## Tue Nov 12 06:15:26 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/M/MMD2_bin.20.fa -m mmseqs --itype genome -o MMD2_bin.20 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/MMD2_bin.20 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
MMD2_k127_1007844_3	1254432.SCE1572_05425	1.787e-88	310.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,42QV3@68525|delta/epsilon subdivisions,2WMT2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
MMD2_k127_1007844_1	1248916.ANFY01000004_gene1771	1.042e-198	645.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,2KD4R@204457|Sphingomonadales	204457|Sphingomonadales	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
MMD2_k127_1007844_11	1101195.Meth11DRAFT_1464	6.202e-25	110.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1007844_9	861299.J421_5704	8.137e-28	125.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
MMD2_k127_1007844_2	1123033.ARNF01000052_gene1018	1.256e-144	469.0	COG0477@1|root,COG2814@2|Bacteria,1NGB4@1224|Proteobacteria,1RZ75@1236|Gammaproteobacteria,3NSX2@468|Moraxellaceae	1236|Gammaproteobacteria	EGP	MFS/sugar transport protein	phlE	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMD2_k127_1007844_7	398527.Bphyt_1723	9.791e-39	151.0	COG1853@1|root,COG1853@2|Bacteria,1PMEZ@1224|Proteobacteria,2W4CH@28216|Betaproteobacteria,1K6GY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
MMD2_k127_1007844_0	357808.RoseRS_2569	4.586e-261	812.0	COG2368@1|root,COG2368@2|Bacteria,2G7XE@200795|Chloroflexi,3764P@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
MMD2_k127_1007844_4	1549858.MC45_01500	9.017e-58	222.0	COG4773@1|root,COG4773@2|Bacteria,1QWUE@1224|Proteobacteria,2UP1W@28211|Alphaproteobacteria,2K3PE@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_1007844_10	1549858.MC45_01500	4.961e-25	114.0	COG4773@1|root,COG4773@2|Bacteria,1QWUE@1224|Proteobacteria,2UP1W@28211|Alphaproteobacteria,2K3PE@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_1007844_6	1114964.L485_02685	6.408e-45	176.0	COG4977@1|root,COG4977@2|Bacteria,1MXZQ@1224|Proteobacteria,2U38S@28211|Alphaproteobacteria,2K5CM@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
MMD2_k127_1007844_8	1242864.D187_000582	3.532e-28	124.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,438XH@68525|delta/epsilon subdivisions,2X42Y@28221|Deltaproteobacteria,2YY4D@29|Myxococcales	28221|Deltaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMD2_k127_1007844_15	1463917.JODC01000004_gene6005	7.828e-05	46.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
MMD2_k127_1007844_12	378806.STAUR_7428	6.071e-20	96.0	COG0789@1|root,COG0789@2|Bacteria,1RGW6@1224|Proteobacteria,431R4@68525|delta/epsilon subdivisions,2WWG9@28221|Deltaproteobacteria,2Z0PM@29|Myxococcales	28221|Deltaproteobacteria	K	MerR, DNA binding	-	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
MMD2_k127_1007844_5	365046.Rta_05370	4.151e-45	165.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,2VHM0@28216|Betaproteobacteria,4ABI5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phenazine biosynthesis protein phzf family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
MMD2_k127_1017536_5	240016.ABIZ01000001_gene1283	2.506e-10	64.0	COG1670@1|root,COG1670@2|Bacteria,46U79@74201|Verrucomicrobia,2IVSC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1017536_4	335283.Neut_1064	5.751e-58	207.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2VTIJ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM TspO MBR family protein	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
MMD2_k127_1017536_1	523791.Kkor_0376	6.226e-113	381.0	COG0654@1|root,COG0654@2|Bacteria,1R7UC@1224|Proteobacteria,1S1B9@1236|Gammaproteobacteria,1XQV5@135619|Oceanospirillales	135619|Oceanospirillales	CH	FAD binding domain	-	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
MMD2_k127_1017536_0	325777.GW15_0207195	4.606e-140	456.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,1X3FQ@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
MMD2_k127_1017536_3	1305737.JAFX01000001_gene2856	3.335e-65	228.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
MMD2_k127_1017536_2	765910.MARPU_15475	6.996e-88	300.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1WVWS@135613|Chromatiales	135613|Chromatiales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
MMD2_k127_1030439_4	519989.ECTPHS_00929	5.183e-103	342.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales	135613|Chromatiales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
MMD2_k127_1030439_14	1415779.JOMH01000001_gene1231	7.476e-21	100.0	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1X7RJ@135614|Xanthomonadales	135614|Xanthomonadales	S	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
MMD2_k127_1030439_6	1121943.KB899998_gene1609	2.101e-97	325.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XI77@135619|Oceanospirillales	135619|Oceanospirillales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMD2_k127_1030439_12	1266909.AUAG01000004_gene2119	3.106e-38	146.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,1WYD9@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
MMD2_k127_1030439_1	857087.Metme_0891	1.945e-192	609.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1XE7G@135618|Methylococcales	135618|Methylococcales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
MMD2_k127_1030439_5	1049564.TevJSym_at00460	1.066e-98	332.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1J4JX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMD2_k127_1030439_13	519989.ECTPHS_00894	5.522e-32	142.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1WY2X@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
MMD2_k127_1030439_8	1397528.Q671_00210	3.22e-84	287.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1XHA1@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
MMD2_k127_1030439_0	1158760.AQXP01000055_gene1236	1.697e-233	730.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,1WWBG@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
MMD2_k127_1030439_11	396588.Tgr7_0009	7.4e-66	231.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S27K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,MipZ
MMD2_k127_1030439_9	519989.ECTPHS_07491	2.735e-74	259.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1WY8N@135613|Chromatiales	135613|Chromatiales	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
MMD2_k127_1030439_7	396588.Tgr7_0032	7.748e-85	300.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1WYMY@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
MMD2_k127_1030439_18	1101195.Meth11DRAFT_0916	1.312e-05	54.0	2BCK1@1|root,32662@2|Bacteria,1RHH4@1224|Proteobacteria,2VSPG@28216|Betaproteobacteria,2KN8W@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
MMD2_k127_1030439_16	243233.MCA2138	4.878e-15	79.0	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1XFG1@135618|Methylococcales	135618|Methylococcales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
MMD2_k127_1030439_2	1333856.L686_01280	2.658e-148	484.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1YZQ3@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	O	Magnesium chelatase, subunit	comM	GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
MMD2_k127_1030439_3	1042377.AFPJ01000051_gene35	2.79e-125	420.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,4642U@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1030439_10	1121935.AQXX01000142_gene2325	7.167e-66	244.0	28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,1XNAN@135619|Oceanospirillales	135619|Oceanospirillales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1030439_17	234267.Acid_3559	6.313e-15	78.0	COG0577@1|root,COG0577@2|Bacteria,3Y3Z1@57723|Acidobacteria	234267.Acid_3559|-	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1035972_5	627192.SLG_05610	2.053e-103	364.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2K3KA@204457|Sphingomonadales	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_1035972_2	1304880.JAGB01000002_gene2119	1.545e-147	478.0	COG0499@1|root,COG0499@2|Bacteria,1TQY0@1239|Firmicutes,248S3@186801|Clostridia	186801|Clostridia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMD2_k127_1035972_3	429009.Adeg_0967	4.469e-127	419.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,42EXU@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMD2_k127_1035972_6	1492922.GY26_15840	1.61e-43	164.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,1J6JG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	menI	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901576,GO:1901661,GO:1901663	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
MMD2_k127_1035972_7	911045.PSE_0921	9.626e-34	135.0	COG3791@1|root,COG3791@2|Bacteria,1REMP@1224|Proteobacteria,2U61P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMD2_k127_1035972_0	1392838.AWNM01000041_gene1362	0.0	1367.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,3T1QU@506|Alcaligenaceae	28216|Betaproteobacteria	U	efflux pump	acrB	-	-	ko:K18138,ko:K18322	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00645,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.41	-	-	ACR_tran
MMD2_k127_1035972_4	1120999.JONM01000008_gene2090	2.505e-115	387.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,2KPHI@206351|Neisseriales	206351|Neisseriales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
MMD2_k127_1035972_9	1123504.JQKD01000002_gene3653	1.376e-22	111.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VVGR@28216|Betaproteobacteria,4AJFU@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD2_k127_1035972_10	1003200.AXXA_28490	1.478e-20	108.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2VR28@28216|Betaproteobacteria	28216|Betaproteobacteria	S	carboxymuconolactone decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMD2_k127_1035972_1	1122603.ATVI01000005_gene3835	2.694e-189	606.0	COG3946@1|root,COG3946@2|Bacteria,1R7R5@1224|Proteobacteria,1RS2B@1236|Gammaproteobacteria,1XBZD@135614|Xanthomonadales	135614|Xanthomonadales	U	Bacterial virulence protein (VirJ)	-	-	-	-	-	-	-	-	-	-	-	-	VirJ
MMD2_k127_1035972_8	653045.Strvi_4559	2.293e-23	111.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_1056999_10	555793.WSK_1941	0.0004406	49.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1056999_9	1117314.PCIT_09689	0.0002281	47.0	2DXAA@1|root,3443N@2|Bacteria,1NMBZ@1224|Proteobacteria,1SIFW@1236|Gammaproteobacteria,2Q3M9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
MMD2_k127_1056999_0	309807.SRU_0446	5.623e-257	818.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1FJYI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
MMD2_k127_1056999_5	1163617.SCD_n00317	1.902e-79	277.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-3 protein	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
MMD2_k127_1056999_3	1163617.SCD_n00316	8.272e-93	334.0	COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria	1224|Proteobacteria	P	Periplasmic solute binding protein	znuA	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
MMD2_k127_1056999_2	1163617.SCD_n00315	7.221e-108	368.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria	28216|Betaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1056999_8	69279.BG36_16585	5.19e-15	84.0	COG4319@1|root,COG4319@2|Bacteria,1PNNX@1224|Proteobacteria,2UKH1@28211|Alphaproteobacteria,43NK7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_1056999_4	1458357.BG58_40540	2.236e-86	299.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,2VR2P@28216|Betaproteobacteria,1K78M@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
MMD2_k127_1056999_6	1472418.BBJC01000004_gene1788	1.056e-65	239.0	2CBAE@1|root,31814@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1056999_1	1121035.AUCH01000007_gene536	8.094e-246	783.0	COG1032@1|root,COG1032@2|Bacteria,1PK5W@1224|Proteobacteria,2VJIN@28216|Betaproteobacteria,2KVTD@206389|Rhodocyclales	206389|Rhodocyclales	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD2_k127_1056999_7	62928.azo1101	8.254e-22	95.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2VQAQ@28216|Betaproteobacteria,2KW2Q@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
MMD2_k127_1065493_2	794903.OPIT5_24040	9.992e-115	378.0	COG0667@1|root,COG0667@2|Bacteria,46SC2@74201|Verrucomicrobia,3K7X7@414999|Opitutae	414999|Opitutae	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD2_k127_1065493_1	1415779.JOMH01000001_gene76	5.622e-121	406.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
MMD2_k127_1065493_0	1231391.AMZF01000039_gene547	1.023e-126	426.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2W8GX@28216|Betaproteobacteria,3T709@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMD2_k127_1065493_3	314254.OA2633_13225	1.815e-92	316.0	COG0627@1|root,COG0627@2|Bacteria,1QIRQ@1224|Proteobacteria,2TUU5@28211|Alphaproteobacteria,43Z22@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
MMD2_k127_1065493_5	675635.Psed_0911	2.276e-43	162.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMD2_k127_1065493_7	404589.Anae109_2821	2.383e-33	133.0	COG3791@1|root,COG3791@2|Bacteria,1N7AZ@1224|Proteobacteria	1224|Proteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMD2_k127_1065493_6	1112217.PPL19_16210	2.814e-35	137.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Translation Initiation Factor	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
MMD2_k127_1065493_8	3055.EDP02662	5.634e-28	123.0	COG0494@1|root,2QT89@2759|Eukaryota,37JK2@33090|Viridiplantae,34MH7@3041|Chlorophyta	3041|Chlorophyta	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMD2_k127_1065493_4	344747.PM8797T_14489	1.842e-67	237.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Acetyltransf_3
MMD2_k127_1112855_11	272560.BPSL3167	2.101e-108	372.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,1K15K@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
MMD2_k127_1112855_7	765914.ThisiDRAFT_0940	2.679e-123	413.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
MMD2_k127_1112855_24	1123261.AXDW01000003_gene1860	1.776e-48	179.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1X6GJ@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
MMD2_k127_1112855_32	1123279.ATUS01000002_gene252	9.265e-13	79.0	COG2831@1|root,COG2831@2|Bacteria,1MWWH@1224|Proteobacteria,1RREH@1236|Gammaproteobacteria,1J65I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	PFAM Ig domain protein, group 1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1
MMD2_k127_1112855_5	1122603.ATVI01000006_gene499	6.458e-207	666.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1X3SF@135614|Xanthomonadales	135614|Xanthomonadales	U	Type II secretory pathway, component HofQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
MMD2_k127_1112855_26	1033802.SSPSH_003542	3.611e-45	169.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	pilus assembly protein pilp	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
MMD2_k127_1112855_21	768671.ThimaDRAFT_2541	9.76e-55	207.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1WXKR@135613|Chromatiales	135613|Chromatiales	NU	Pilus assembly protein PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
MMD2_k127_1112855_25	379731.PST_0554	4.908e-46	172.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1YZYM@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NU	pilus assembly protein PilN	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
MMD2_k127_1112855_9	396588.Tgr7_3023	1.004e-110	368.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
MMD2_k127_1112855_4	1207076.ALAT01000011_gene1480	4.074e-218	704.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1Z247@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	COG5009 Membrane carboxypeptidase penicillin-binding protein	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
MMD2_k127_1112855_28	666685.R2APBS1_3346	1.776e-36	149.0	COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,1S81F@1236|Gammaproteobacteria,1X5UH@135614|Xanthomonadales	135614|Xanthomonadales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1112855_30	765912.Thimo_0079	7.26e-31	125.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1WZ1M@135613|Chromatiales	135613|Chromatiales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
MMD2_k127_1112855_17	1129374.AJE_14725	1.172e-61	222.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,466HT@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212	Ham1p_like
MMD2_k127_1112855_12	857087.Metme_4371	5.649e-104	342.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1XEH9@135618|Methylococcales	135618|Methylococcales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
MMD2_k127_1112855_19	1123354.AUDR01000013_gene656	3.749e-55	201.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,1KS5M@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
MMD2_k127_1112855_16	472759.Nhal_0748	9.127e-68	240.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1WX83@135613|Chromatiales	135613|Chromatiales	S	PFAM YicC-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
MMD2_k127_1112855_18	1123517.JOMR01000001_gene299	1.24e-56	215.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,460JB@72273|Thiotrichales	72273|Thiotrichales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
MMD2_k127_1112855_31	187272.Mlg_2443	2.242e-23	106.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales	135613|Chromatiales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
MMD2_k127_1112855_2	519989.ECTPHS_04239	2.467e-255	806.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
MMD2_k127_1112855_22	1249627.D779_0944	1.416e-50	183.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1WY7E@135613|Chromatiales	135613|Chromatiales	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
MMD2_k127_1112855_3	1123253.AUBD01000005_gene193	3.146e-223	711.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1X42Y@135614|Xanthomonadales	135614|Xanthomonadales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HHH_5,Helicase_C,RecG_wedge
MMD2_k127_1112855_15	472759.Nhal_0761	6.169e-89	327.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1WWA7@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
MMD2_k127_1112855_29	1415780.JPOG01000001_gene190	5.398e-33	138.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1X6Y9@135614|Xanthomonadales	135614|Xanthomonadales	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
MMD2_k127_1112855_6	1122604.JONR01000043_gene3174	5.22e-143	465.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1X3XQ@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
MMD2_k127_1112855_20	243159.AFE_0245	4.426e-55	207.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,2NCH7@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
MMD2_k127_1112855_14	686340.Metal_1807	5.056e-98	329.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1XECZ@135618|Methylococcales	135618|Methylococcales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
MMD2_k127_1112855_0	1260251.SPISAL_01500	1.411e-283	877.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1WWX1@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
MMD2_k127_1112855_23	1236541.BALL01000016_gene2291	1.646e-49	181.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,2Q9TN@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM cytochrome c oxidase assembly protein CtaG Cox11	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
MMD2_k127_1112855_8	713586.KB900536_gene1816	2.741e-121	396.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1WX89@135613|Chromatiales	135613|Chromatiales	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
MMD2_k127_1112855_34	1123504.JQKD01000018_gene2078	0.0005338	52.0	2E53D@1|root,32ZWH@2|Bacteria,1N979@1224|Proteobacteria,2VVRY@28216|Betaproteobacteria,4AFBB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2909)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2909
MMD2_k127_1112855_27	243233.MCA0131	6.623e-41	160.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1XEXY@135618|Methylococcales	135618|Methylococcales	S	SURF1-like protein	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
MMD2_k127_1112855_33	1454202.PPBDW_80186___1	1.799e-09	70.0	COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1S85U@1236|Gammaproteobacteria,1XXWZ@135623|Vibrionales	135623|Vibrionales	S	signal sequence binding	VVA1110	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1112855_13	396588.Tgr7_3001	1.593e-100	338.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1WZSA@135613|Chromatiales	135613|Chromatiales	O	cytochrome oxidase assembly	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
MMD2_k127_1112855_10	1137799.GZ78_22695	1.662e-108	359.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1XI1Y@135619|Oceanospirillales	135619|Oceanospirillales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
MMD2_k127_1112855_1	243233.MCA1037	5.353e-279	874.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XEAI@135618|Methylococcales	135618|Methylococcales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
MMD2_k127_111886_4	412597.AEPN01000019_gene1070	1.495e-80	272.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,2PV2W@265|Paracoccus	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
MMD2_k127_111886_2	1231185.BAMP01000084_gene3609	1.253e-131	425.0	COG0395@1|root,COG0395@2|Bacteria,1MUT9@1224|Proteobacteria,2TRQ0@28211|Alphaproteobacteria,43HJR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K17317	ko02010,map02010	M00207,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
MMD2_k127_111886_3	1192868.CAIU01000029_gene3895	4.165e-123	409.0	COG1175@1|root,COG1175@2|Bacteria,1MU84@1224|Proteobacteria,2TRM5@28211|Alphaproteobacteria,43IWB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	COG1175 ABC-type sugar transport systems permease components	amyD	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
MMD2_k127_111886_1	1122214.AQWH01000012_gene3741	1.547e-185	588.0	COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,2TUCZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1
MMD2_k127_111886_0	264198.Reut_A1185	1.193e-294	932.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VNZQ@28216|Betaproteobacteria,1KGKU@119060|Burkholderiaceae	28216|Betaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMD2_k127_11483_0	686340.Metal_1832	0.0	1365.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1XDT8@135618|Methylococcales	135618|Methylococcales	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMD2_k127_11483_7	1183438.GKIL_4354	2.881e-120	417.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_11483_6	113395.AXAI01000005_gene3909	7.296e-124	399.0	COG0625@1|root,COG0625@2|Bacteria,1NE6Z@1224|Proteobacteria,2TVN6@28211|Alphaproteobacteria,3JVXF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_N
MMD2_k127_11483_11	314270.RB2083_766	1.069e-87	297.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,3ZHH4@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N,GST_N_3
MMD2_k127_11483_17	1206741.BAFX01000075_gene4068	1.538e-50	190.0	COG2764@1|root,COG3153@1|root,COG2764@2|Bacteria,COG3153@2|Bacteria,2IM8Y@201174|Actinobacteria,4G9ZP@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_11483_21	1278073.MYSTI_01581	4.204e-37	159.0	COG0454@1|root,COG0456@2|Bacteria,1RKSW@1224|Proteobacteria	1224|Proteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMD2_k127_11483_13	448385.sce0923	5.76e-72	256.0	COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,43DWE@68525|delta/epsilon subdivisions,2WZ1W@28221|Deltaproteobacteria,2Z153@29|Myxococcales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMD2_k127_11483_8	160492.XF_1730	7.862e-109	361.0	COG0583@1|root,COG0583@2|Bacteria,1MU7H@1224|Proteobacteria,1RPF8@1236|Gammaproteobacteria,1X5FS@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD2_k127_11483_15	682795.AciX8_1124	3.143e-58	205.0	COG2259@1|root,COG2259@2|Bacteria,3Y7UA@57723|Acidobacteria,2JMZW@204432|Acidobacteriia	204432|Acidobacteriia	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
MMD2_k127_11483_22	331869.BAL199_02244	2.664e-28	126.0	COG0454@1|root,COG0456@2|Bacteria,1RIBM@1224|Proteobacteria,2UBNA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMD2_k127_11483_14	1123237.Salmuc_02887	3.182e-61	224.0	COG0697@1|root,COG0697@2|Bacteria,1R81I@1224|Proteobacteria,2VFWV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD2_k127_11483_12	1218076.BAYB01000022_gene3847	3.658e-73	259.0	COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2W14Y@28216|Betaproteobacteria,1K4G8@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMD2_k127_11483_24	211586.SO_2061	2.623e-06	55.0	2AY83@1|root,31QA8@2|Bacteria,1QMYE@1224|Proteobacteria,1TK9K@1236|Gammaproteobacteria,2QCP4@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_11483_16	448385.sce5181	6.867e-51	197.0	COG2706@1|root,COG2706@2|Bacteria,1NG69@1224|Proteobacteria	1224|Proteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
MMD2_k127_11483_10	1384056.N787_06560	7.552e-99	336.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,1X7AT@135614|Xanthomonadales	135614|Xanthomonadales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
MMD2_k127_11483_3	627192.SLG_34920	6.472e-189	626.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2UNZR@28211|Alphaproteobacteria,2KECI@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_11483_2	1260251.SPISAL_07880	2.085e-292	928.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1X078@135613|Chromatiales	135613|Chromatiales	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
MMD2_k127_11483_9	396588.Tgr7_0496	9.978e-103	357.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,1RY02@1236|Gammaproteobacteria,1WXG2@135613|Chromatiales	135613|Chromatiales	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_11483_18	1089552.KI911559_gene2387	6.367e-49	187.0	COG0705@1|root,COG0705@2|Bacteria,1N258@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMD2_k127_11483_20	1090318.ATTI01000001_gene575	1.548e-40	155.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2TRRN@28211|Alphaproteobacteria,2KD23@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
MMD2_k127_11483_23	292415.Tbd_0063	1.228e-17	93.0	2EH48@1|root,338P5@2|Bacteria,1NFS9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_11483_19	1123242.JH636435_gene2942	8.728e-42	169.0	2E79V@1|root,331TF@2|Bacteria,2J35R@203682|Planctomycetes	203682|Planctomycetes	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMD2_k127_11483_4	1095769.CAHF01000011_gene2110	2.279e-186	593.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,2VHJ7@28216|Betaproteobacteria,475RY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	SpoVR like protein	spoVR1	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
MMD2_k127_11483_5	314278.NB231_10398	1.256e-125	414.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,1WWH8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
MMD2_k127_11483_1	314278.NB231_10393	1.867e-303	944.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,1WWXB@135613|Chromatiales	135613|Chromatiales	T	PFAM PrkA AAA	-	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
MMD2_k127_1167945_7	1049564.TevJSym_aj00110	7.017e-127	421.0	COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,1J75U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
MMD2_k127_1167945_26	1117647.M5M_12200	1.369e-50	188.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1J6KV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
MMD2_k127_1167945_21	1049564.TevJSym_aj00080	3.389e-62	220.0	COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,1JADW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
MMD2_k127_1167945_20	349521.HCH_02595	6.633e-70	245.0	COG3807@1|root,COG3807@2|Bacteria,1RE8W@1224|Proteobacteria,1S4BU@1236|Gammaproteobacteria,1XPIQ@135619|Oceanospirillales	135619|Oceanospirillales	S	COG3103 SH3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,SH3_3,SH3_4
MMD2_k127_1167945_1	1049564.TevJSym_aj00060	1.281e-260	832.0	COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,1J98N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
MMD2_k127_1167945_9	1085623.GNIT_3659	2.66e-124	414.0	28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,4667S@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1167945_0	349521.HCH_02592	2.446e-266	849.0	COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,1XN5T@135619|Oceanospirillales	135619|Oceanospirillales	E	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
MMD2_k127_1167945_2	1129794.C427_0636	1.104e-197	629.0	2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,4657P@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1167945_22	861299.J421_2165	8.316e-61	226.0	COG1975@1|root,COG1975@2|Bacteria,1ZTYH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
MMD2_k127_1167945_16	1500894.JQNN01000001_gene1524	1.054e-77	267.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,4723E@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186,ko:K16875	ko00130,ko00365,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R10213,R11225	RC00391,RC00814,RC03086,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
MMD2_k127_1167945_13	1417296.U879_14560	7.863e-94	313.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2TSYJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type molybdate transport system, permease component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
MMD2_k127_1167945_12	314264.ROS217_12646	4.387e-94	320.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,46QMS@74030|Roseovarius	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
MMD2_k127_1167945_19	1157708.KB907450_gene5305	2.339e-73	265.0	COG0346@1|root,COG0346@2|Bacteria,1MVVU@1224|Proteobacteria,2VKDD@28216|Betaproteobacteria,4ABYA@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_1167945_28	1437824.BN940_08551	2.553e-36	141.0	COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,2VQ2B@28216|Betaproteobacteria,3T7IJ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	-	-	1.13.11.8	ko:K04100	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA
MMD2_k127_1167945_8	1121033.AUCF01000026_gene2985	8.202e-127	420.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,2JVBN@204441|Rhodospirillales	204441|Rhodospirillales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigA,LigB
MMD2_k127_1167945_10	1298867.AUES01000012_gene5510	2.605e-123	403.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,3JSFK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	MA20_26630	-	3.1.1.57	ko:K10221	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R04277	RC03110	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
MMD2_k127_1167945_5	1056512.D515_04448	6.149e-142	460.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria,1XW82@135623|Vibrionales	135623|Vibrionales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
MMD2_k127_1167945_3	46429.BV95_03087	1.119e-151	496.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
MMD2_k127_1167945_18	378806.STAUR_1831	1.669e-75	281.0	2EMFP@1|root,33F4E@2|Bacteria,1NH35@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1167945_15	1192124.LIG30_1182	2.155e-79	271.0	COG0500@1|root,COG2226@2|Bacteria,1R42G@1224|Proteobacteria,2W3KQ@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMD2_k127_1167945_17	1280952.HJA_13185	4.321e-77	284.0	COG3394@1|root,COG3394@2|Bacteria,1N6E6@1224|Proteobacteria,2UCEC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	YdjC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
MMD2_k127_1167945_31	1117108.PAALTS15_27774	2.872e-09	64.0	COG2246@1|root,COG2246@2|Bacteria,1VFGI@1239|Firmicutes,4HZ8T@91061|Bacilli,26ZUN@186822|Paenibacillaceae	91061|Bacilli	S	GtrA-like protein	yngA	-	-	-	-	-	-	-	-	-	-	-	GtrA
MMD2_k127_1167945_11	1167006.UWK_01989	1.579e-111	377.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2WJV8@28221|Deltaproteobacteria,2MIJX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
MMD2_k127_1167945_23	378806.STAUR_6079	8.296e-60	214.0	COG2227@1|root,COG2227@2|Bacteria,1QX75@1224|Proteobacteria,43E3D@68525|delta/epsilon subdivisions,2X7AR@28221|Deltaproteobacteria,2Z3ER@29|Myxococcales	28221|Deltaproteobacteria	H	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMD2_k127_1167945_6	1205680.CAKO01000002_gene2811	2.971e-136	443.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	MA20_07800	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMD2_k127_1167945_25	580332.Slit_1021	3.376e-55	198.0	COG2110@1|root,COG2110@2|Bacteria,1MVYN@1224|Proteobacteria,2VH7H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Appr-1-p processing	-	-	-	-	-	-	-	-	-	-	-	-	Macro
MMD2_k127_1167945_4	1056512.D515_04442	6.47e-149	479.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,1XWGM@135623|Vibrionales	135623|Vibrionales	S	PrpF protein	-	-	5.3.2.8	ko:K16514	ko00362,ko01120,map00362,map01120	-	R07839	RC02426	ko00000,ko00001,ko01000	-	-	-	PrpF
MMD2_k127_1167945_14	472759.Nhal_2208	4.434e-88	302.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1WW4N@135613|Chromatiales	135613|Chromatiales	C	PFAM aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD2_k127_1167945_27	264198.Reut_B4908	1.833e-40	173.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2VPBZ@28216|Betaproteobacteria,1K3AW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1167945_24	309801.trd_1433	1.151e-59	222.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_1167945_30	326427.Cagg_2097	2.797e-17	92.0	COG0508@1|root,COG0508@2|Bacteria,2G5TB@200795|Chloroflexi,3759C@32061|Chloroflexia	32061|Chloroflexia	C	catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMD2_k127_119218_0	622637.KE124770_gene148	1.788e-174	554.0	COG1389@1|root,COG1389@2|Bacteria,1R6T0@1224|Proteobacteria	1224|Proteobacteria	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
MMD2_k127_119218_3	1122611.KB903968_gene2329	5.502e-82	292.0	COG0277@1|root,COG0277@2|Bacteria,2GKQR@201174|Actinobacteria,4EFTT@85012|Streptosporangiales	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
MMD2_k127_119218_1	713586.KB900536_gene2819	3.609e-130	449.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
MMD2_k127_119218_2	1123073.KB899244_gene303	4.316e-120	396.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1X46A@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
MMD2_k127_119218_6	1121013.P873_07035	2.571e-53	193.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1X6FA@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
MMD2_k127_119218_9	296591.Bpro_2194	4.318e-10	65.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2VVSP@28216|Betaproteobacteria,4AF4Z@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMD2_k127_119218_5	452637.Oter_0947	1.428e-53	191.0	COG0314@1|root,COG0314@2|Bacteria,46ZD6@74201|Verrucomicrobia,3K9NY@414999|Opitutae	414999|Opitutae	H	PFAM molybdopterin biosynthesis MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
MMD2_k127_119218_8	1223523.H340_09815	6.907e-27	119.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria	201174|Actinobacteria	NU	MobA-related protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
MMD2_k127_119218_7	1123073.KB899241_gene1978	3.898e-35	140.0	COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
MMD2_k127_119218_4	1283300.ATXB01000001_gene2306	5.067e-71	249.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XEKU@135618|Methylococcales	135618|Methylococcales	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
MMD2_k127_1258751_5	1123073.KB899243_gene664	1.288e-158	510.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1X4AT@135614|Xanthomonadales	135614|Xanthomonadales	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
MMD2_k127_1258751_15	1209072.ALBT01000032_gene2092	6.981e-33	134.0	2CK8Q@1|root,31PVK@2|Bacteria,1RIRH@1224|Proteobacteria,1SD2E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1258751_16	570952.ATVH01000015_gene1207	3.887e-25	110.0	2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2UH5V@28211|Alphaproteobacteria,2JU5C@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1258751_17	666685.R2APBS1_3221	9.089e-24	108.0	COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria,1S5BT@1236|Gammaproteobacteria,1XAZ6@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMD2_k127_1258751_10	365046.Rta_32130	6.019e-65	229.0	COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,2VT03@28216|Betaproteobacteria,4AHAF@80864|Comamonadaceae	28216|Betaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMD2_k127_1258751_8	365046.Rta_32140	6.048e-93	317.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,2VSN1@28216|Betaproteobacteria,4AH3E@80864|Comamonadaceae	28216|Betaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
MMD2_k127_1258751_14	1215092.PA6_034_00060	1.633e-35	144.0	28IAG@1|root,2Z8D2@2|Bacteria,1P5EH@1224|Proteobacteria,1RYCA@1236|Gammaproteobacteria,1YCYG@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
MMD2_k127_1258751_12	365046.Rta_32160	1.09e-47	181.0	28IAG@1|root,33XQD@2|Bacteria,1NWD8@1224|Proteobacteria,2W2ST@28216|Betaproteobacteria,4AHXC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
MMD2_k127_1258751_13	1157708.KB907463_gene717	4.377e-41	173.0	COG3064@1|root,COG3064@2|Bacteria,1PUUY@1224|Proteobacteria,2VXQ4@28216|Betaproteobacteria,4AGHJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
MMD2_k127_1258751_7	1157708.KB907463_gene716	1.35e-124	407.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,4AG8Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
MMD2_k127_1258751_6	1157708.KB907463_gene715	3.033e-131	437.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,2WFR3@28216|Betaproteobacteria,4AGSU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMD2_k127_1258751_18	595537.Varpa_4158	2.618e-14	78.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2VKFT@28216|Betaproteobacteria,4ABEC@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator	lytT	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
MMD2_k127_1258751_3	1117379.BABA_03459	2.127e-220	716.0	COG4993@1|root,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli,1ZFCQ@1386|Bacillus	91061|Bacilli	CG	COG4993 Glucose dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_1258751_4	1385511.N783_00010	1.019e-192	618.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli	91061|Bacilli	CG	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_1258751_2	1117379.BABA_03459	1.775e-229	731.0	COG4993@1|root,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli,1ZFCQ@1386|Bacillus	91061|Bacilli	CG	COG4993 Glucose dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_1258751_1	644968.DFW101_0023	2.687e-230	739.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MAGR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
MMD2_k127_1258751_9	1449065.JMLL01000010_gene529	2.16e-65	228.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,43JYP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	methionine sulfoxide reductase	msrB1	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
MMD2_k127_1258751_0	1349767.GJA_1853	3.864e-247	776.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2VJF0@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
MMD2_k127_1258751_11	1217718.ALOU01000032_gene1402	4.924e-57	204.0	COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2VKZ6@28216|Betaproteobacteria,1K04D@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA2	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
MMD2_k127_1344679_28	765913.ThidrDRAFT_3528	1.954e-25	114.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1WX0R@135613|Chromatiales	135613|Chromatiales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
MMD2_k127_1344679_24	1458357.BG58_20390	4.249e-43	162.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,1JZUQ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
MMD2_k127_1344679_15	1384054.N790_06620	2.548e-97	329.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1X2Y9@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
MMD2_k127_1344679_27	1283300.ATXB01000001_gene1314	3.832e-27	119.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1XF7V@135618|Methylococcales	135618|Methylococcales	M	Belongs to the skp family	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
MMD2_k127_1344679_2	697282.Mettu_2893	3.439e-193	637.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XDRZ@135618|Methylococcales	135618|Methylococcales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
MMD2_k127_1344679_10	187272.Mlg_1856	1.249e-127	422.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1WW2V@135613|Chromatiales	135613|Chromatiales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
MMD2_k127_1344679_23	1042375.AFPL01000031_gene755	3.449e-47	180.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,1T63B@1236|Gammaproteobacteria,46DFC@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
MMD2_k127_1344679_22	243233.MCA0570	2.157e-63	233.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1XEV5@135618|Methylococcales	135618|Methylococcales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
MMD2_k127_1344679_12	1260251.SPISAL_04490	1.1e-108	356.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1WX9S@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
MMD2_k127_1344679_17	396588.Tgr7_1160	2.489e-91	311.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales	135613|Chromatiales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
MMD2_k127_1344679_16	1234364.AMSF01000027_gene3466	2.027e-95	338.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1X2XU@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
MMD2_k127_1344679_9	396588.Tgr7_1158	3.799e-129	417.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1WX9V@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMD2_k127_1344679_1	396588.Tgr7_1157	1.175e-278	882.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales	135613|Chromatiales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2
MMD2_k127_1344679_11	396588.Tgr7_1152	1.329e-127	412.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1WVX8@135613|Chromatiales	135613|Chromatiales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
MMD2_k127_1344679_8	1049564.TevJSym_ax00070	1.941e-135	436.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1J56X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMD2_k127_1344679_5	1049564.TevJSym_ax00060	1.481e-175	560.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1J4TU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Domain of unknown function (DUF3333)	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
MMD2_k127_1344679_3	1265505.ATUG01000001_gene3102	1.441e-180	576.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2MHPU@213118|Desulfobacterales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
MMD2_k127_1344679_7	1121403.AUCV01000001_gene703	1.411e-140	456.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,42MJ3@68525|delta/epsilon subdivisions,2WKD5@28221|Deltaproteobacteria,2MHQC@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMD2_k127_1344679_6	1049564.TevJSym_ad00370	2.694e-142	461.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1J4Y7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2485	M20_dimer,Peptidase_M20
MMD2_k127_1344679_25	913325.N799_09680	5.579e-41	163.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,1S6WD@1236|Gammaproteobacteria,1X6GW@135614|Xanthomonadales	135614|Xanthomonadales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
MMD2_k127_1344679_20	1033802.SSPSH_002133	2.279e-79	272.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
MMD2_k127_1344679_14	765914.ThisiDRAFT_2327	8.857e-102	348.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1WWCF@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
MMD2_k127_1344679_18	743721.Psesu_2051	1.251e-89	301.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1X316@135614|Xanthomonadales	135614|Xanthomonadales	KT	Two component response regulator for the phosphate regulon	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_1344679_26	90371.CY43_09295	2.117e-31	140.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,3ZJDC@590|Salmonella	1236|Gammaproteobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
MMD2_k127_1344679_4	396588.Tgr7_1409	3.567e-178	579.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales	135613|Chromatiales	L	Helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
MMD2_k127_1344679_29	1122218.KB893653_gene829	1.317e-08	64.0	COG4719@1|root,COG4719@2|Bacteria,1N3PM@1224|Proteobacteria,2U8UQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1344679_0	1123253.AUBD01000005_gene111	7.736e-283	884.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,1RNGQ@1236|Gammaproteobacteria,1X482@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
MMD2_k127_1344679_21	156889.Mmc1_3142	2.5e-67	240.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc,SnoaL_3
MMD2_k127_1344679_19	765911.Thivi_0229	2.939e-82	282.0	COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1WX5D@135613|Chromatiales	135613|Chromatiales	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMD2_k127_1344679_13	1026882.MAMP_01736	9.282e-106	354.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,45ZR3@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
MMD2_k127_1351438_1	1095769.CAHF01000011_gene2142	6.704e-98	331.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,472S7@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	TonB dependent receptor	yncD	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_1351438_9	627192.SLG_09880	4.417e-52	194.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1351438_13	627192.SLG_09870	1.162e-22	103.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1351438_14	1157708.KB907462_gene1038	6.199e-22	99.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2VK72@28216|Betaproteobacteria,4AC52@80864|Comamonadaceae	28216|Betaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	sorA	-	1.8.2.1	ko:K05301	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528	RC00168	ko00000,ko00001,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
MMD2_k127_1351438_8	234267.Acid_4171	9.121e-59	215.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_1351438_5	1121374.KB891586_gene2544	1.487e-77	261.0	2BDUH@1|root,302AN@2|Bacteria,1RF2Q@1224|Proteobacteria	1224|Proteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMD2_k127_1351438_10	926569.ANT_02560	7.238e-47	175.0	COG1595@1|root,COG1595@2|Bacteria,2G96E@200795|Chloroflexi	200795|Chloroflexi	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_1351438_12	383372.Rcas_2698	5.805e-24	113.0	COG5662@1|root,COG5662@2|Bacteria,2G7G7@200795|Chloroflexi	200795|Chloroflexi	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1351438_2	383372.Rcas_2699	3.588e-91	308.0	COG1131@1|root,COG1131@2|Bacteria,2G69S@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_1351438_11	383372.Rcas_3764	2.85e-46	186.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMD2_k127_1351438_6	1211115.ALIQ01000188_gene639	2.583e-75	261.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,2TUCR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMD2_k127_1351438_0	935863.AWZR01000005_gene2169	6.803e-114	375.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,1XC3M@135614|Xanthomonadales	135614|Xanthomonadales	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD2_k127_1351438_4	1122135.KB893168_gene1873	2.446e-84	290.0	COG0697@1|root,COG0697@2|Bacteria,1RI87@1224|Proteobacteria,2UAJW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	permeases of the drug metabolite transporter (DMT) superfamily	MA20_28970	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD2_k127_1351438_3	1298867.AUES01000001_gene1913	2.392e-90	312.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,3JV8N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
MMD2_k127_1351438_15	266117.Rxyl_2933	2.2e-19	100.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria	201174|Actinobacteria	S	CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
MMD2_k127_1351438_7	1049564.TevJSym_ac01690	2.134e-70	246.0	COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria,1S58J@1236|Gammaproteobacteria,1JA86@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
MMD2_k127_1366549_2	379066.GAU_3131	2.842e-170	541.0	COG2303@1|root,COG2303@2|Bacteria,1ZSZW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMD2_k127_1366549_3	247634.GPB2148_188	1.754e-144	470.0	COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,1RMKA@1236|Gammaproteobacteria,1J8ZT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMD2_k127_1366549_1	450851.PHZ_c2154	3.863e-174	551.0	COG1082@1|root,COG1082@2|Bacteria,1MVSJ@1224|Proteobacteria,2TV5J@28211|Alphaproteobacteria,2KFAP@204458|Caulobacterales	204458|Caulobacterales	G	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
MMD2_k127_1366549_0	1121939.L861_10775	1.181e-176	562.0	COG0477@1|root,COG2814@2|Bacteria,1QWEI@1224|Proteobacteria,1T3J4@1236|Gammaproteobacteria,1XS00@135619|Oceanospirillales	135619|Oceanospirillales	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
MMD2_k127_1366549_4	518766.Rmar_1735	6.741e-35	146.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,1FJUS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMD2_k127_1366549_5	1007104.SUS17_2414	1.561e-21	99.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1424699_2	523791.Kkor_2634	4.411e-38	147.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1XH68@135619|Oceanospirillales	135619|Oceanospirillales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
MMD2_k127_1424699_4	1452718.JBOY01000005_gene3322	4.655e-07	57.0	COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	atp synthase	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
MMD2_k127_1424699_1	314278.NB231_10873	1.002e-90	308.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
MMD2_k127_1424699_0	1123279.ATUS01000001_gene2351	3.564e-109	358.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1J5A9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	ATPases involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMD2_k127_1424699_3	326297.Sama_3654	2.92e-33	138.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,2Q9TG@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
MMD2_k127_1475350_6	326297.Sama_0166	1.68e-05	47.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,2Q9TC@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
MMD2_k127_1475350_7	1541065.JRFE01000034_gene6119	6.484e-05	54.0	COG0265@1|root,COG2730@1|root,COG2931@1|root,COG3209@1|root,COG0265@2|Bacteria,COG2730@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,1GJ0K@1117|Cyanobacteria,3VMAI@52604|Pleurocapsales	1117|Cyanobacteria	MQ	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SdrD_B
MMD2_k127_1475350_2	1267535.KB906767_gene1286	9.129e-33	137.0	COG2010@1|root,COG2010@2|Bacteria,3Y846@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_1475350_0	1267535.KB906767_gene1287	2.585e-169	548.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
MMD2_k127_1475350_1	1198452.Jab_2c18550	7.185e-85	291.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
MMD2_k127_1475350_5	1041147.AUFB01000013_gene170	8.864e-06	48.0	2C7AF@1|root,32RIR@2|Bacteria,1R4XV@1224|Proteobacteria,2UUEN@28211|Alphaproteobacteria,4BJHN@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3223
MMD2_k127_1475350_3	883078.HMPREF9695_01197	1.148e-10	67.0	2C7AF@1|root,32RIR@2|Bacteria,1R4XV@1224|Proteobacteria,2U2N6@28211|Alphaproteobacteria,3K0TK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3223
MMD2_k127_1475350_4	926566.Terro_3184	2.214e-07	57.0	2AMVA@1|root,31CS1@2|Bacteria,3Y7GD@57723|Acidobacteria,2JMJK@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1498183_22	1123023.JIAI01000004_gene8204	6.01e-46	175.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
MMD2_k127_1498183_7	13689.BV96_02932	2.196e-172	557.0	COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,2U5D5@28211|Alphaproteobacteria,2K1C7@204457|Sphingomonadales	204457|Sphingomonadales	C	Protein involved in UDP-N-acetylmuramate dehydrogenase activity and amino sugar metabolic process	-	-	1.17.99.1	ko:K05797	ko00623,ko01100,ko01120,map00623,map01100,map01120	-	R02675,R11194	RC00769	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMD2_k127_1498183_28	13689.BV96_02134	4.304e-18	91.0	COG2010@1|root,COG2010@2|Bacteria,1N9X8@1224|Proteobacteria,2UVSW@28211|Alphaproteobacteria,2KB3M@204457|Sphingomonadales	28211|Alphaproteobacteria	C	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMD2_k127_1498183_31	1122603.ATVI01000007_gene1777	2.208e-13	81.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
MMD2_k127_1498183_2	1245469.S58_09690	3.032e-295	944.0	COG3748@1|root,COG3748@2|Bacteria	2|Bacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
MMD2_k127_1498183_6	1245469.S58_09700	1.715e-174	582.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
MMD2_k127_1498183_19	1121904.ARBP01000013_gene358	5.826e-69	265.0	COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,47MG0@768503|Cytophagia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PSCyt1
MMD2_k127_1498183_24	864051.BurJ1DRAFT_0558	2.589e-28	117.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMD2_k127_1498183_15	570967.JMLV01000008_gene1306	8.254e-89	308.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2JPVS@204441|Rhodospirillales	204441|Rhodospirillales	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
MMD2_k127_1498183_20	1122604.JONR01000049_gene752	1.902e-68	245.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,1S7QH@1236|Gammaproteobacteria,1X5S6@135614|Xanthomonadales	135614|Xanthomonadales	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
MMD2_k127_1498183_18	1163617.SCD_n02027	4.177e-71	249.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase 20 kDa subunit	hyfI	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
MMD2_k127_1498183_8	1454004.AW11_01548	2.051e-170	549.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	hyfG	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
MMD2_k127_1498183_4	1163409.UUA_14704	3.984e-246	766.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,1RPB3@1236|Gammaproteobacteria,1XA5T@135614|Xanthomonadales	135614|Xanthomonadales	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
MMD2_k127_1498183_17	1163617.SCD_n02024	4.401e-76	261.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
MMD2_k127_1498183_10	1122604.JONR01000030_gene1324	3.075e-128	445.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,1RPCY@1236|Gammaproteobacteria,1X98P@135614|Xanthomonadales	135614|Xanthomonadales	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
MMD2_k127_1498183_3	1122604.JONR01000030_gene1323	9.382e-269	842.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,1RM9Q@1236|Gammaproteobacteria,1XA2F@135614|Xanthomonadales	135614|Xanthomonadales	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
MMD2_k127_1498183_29	1122604.JONR01000030_gene1322	4.457e-17	89.0	COG3905@1|root,COG3905@2|Bacteria,1N7D2@1224|Proteobacteria,1SCP8@1236|Gammaproteobacteria,1X919@135614|Xanthomonadales	135614|Xanthomonadales	K	copG family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1498183_0	62928.azo0820	0.0	1056.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,2KV5X@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
MMD2_k127_1498183_11	207954.MED92_14148	5.497e-115	377.0	COG3384@1|root,COG3384@2|Bacteria,1MWNC@1224|Proteobacteria,1RPH7@1236|Gammaproteobacteria,1XI23@135619|Oceanospirillales	135619|Oceanospirillales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.15	ko:K00455	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R03303	RC00643	ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
MMD2_k127_1498183_13	404589.Anae109_0481	7.684e-111	368.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,42WB3@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Alpha beta hydrolase	dehH	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMD2_k127_1498183_14	1297742.A176_06754	6.611e-102	345.0	COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria,433T9@68525|delta/epsilon subdivisions,2X3CY@28221|Deltaproteobacteria,2YTTY@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD2_k127_1498183_27	1283300.ATXB01000001_gene78	1.597e-22	105.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1XFKE@135618|Methylococcales	135618|Methylococcales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
MMD2_k127_1498183_23	859657.RPSI07_mp1323	1.921e-29	127.0	COG4967@1|root,COG4967@2|Bacteria,1NBNT@1224|Proteobacteria,2VWJN@28216|Betaproteobacteria,1KDNR@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	pilV	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
MMD2_k127_1498183_21	859657.RPSI07_mp1322	2.98e-46	175.0	COG4966@1|root,COG4966@2|Bacteria,1N06H@1224|Proteobacteria,2VVD9@28216|Betaproteobacteria,1KDGK@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	type 4 fimbrial biogenesis transmembrane	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
MMD2_k127_1498183_25	859657.RPSI07_mp1321	6.55e-26	124.0	COG4726@1|root,COG4726@2|Bacteria,1N5S6@1224|Proteobacteria,2VVF4@28216|Betaproteobacteria,1KDKQ@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX,PilX_N
MMD2_k127_1498183_1	267608.RSp1288	0.0	1046.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,1KBUP@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
MMD2_k127_1498183_26	977880.RALTA_A2324	6.876e-26	121.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,2VW3E@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	pilus assembly protein PilE	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
MMD2_k127_1498183_12	243090.RB13271	1.697e-111	385.0	COG1181@1|root,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
MMD2_k127_1498183_16	595460.RRSWK_02466	3.893e-81	283.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
MMD2_k127_1498183_30	1449976.KALB_7082	3.535e-16	91.0	COG1819@1|root,COG1819@2|Bacteria,2GJMF@201174|Actinobacteria,4DX4R@85010|Pseudonocardiales	201174|Actinobacteria	CG	lipid glycosylation	-	-	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
MMD2_k127_1498183_9	1449976.KALB_7082	1.721e-144	469.0	COG1819@1|root,COG1819@2|Bacteria,2GJMF@201174|Actinobacteria,4DX4R@85010|Pseudonocardiales	201174|Actinobacteria	CG	lipid glycosylation	-	-	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
MMD2_k127_1498183_33	1267533.KB906737_gene1860	9.179e-07	55.0	COG0383@1|root,COG0383@2|Bacteria,3Y2RJ@57723|Acidobacteria,2JI5W@204432|Acidobacteriia	204432|Acidobacteriia	G	glycoside hydrolase family 38	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
MMD2_k127_1498183_32	392499.Swit_4873	7.074e-13	76.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2UBV3@28211|Alphaproteobacteria,2K32E@204457|Sphingomonadales	204457|Sphingomonadales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LysM,RHS_repeat
MMD2_k127_1498183_5	697282.Mettu_0587	1.594e-179	576.0	COG4716@1|root,COG4716@2|Bacteria,1MVTV@1224|Proteobacteria,1RQMG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Myosin-crossreactive antigen	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
MMD2_k127_1498183_34	194867.ALBQ01000011_gene384	3.664e-05	51.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
MMD2_k127_1585304_3	545264.KB898746_gene964	9.909e-11	70.0	COG3901@1|root,COG3901@2|Bacteria,1R0U7@1224|Proteobacteria,1T4PH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
MMD2_k127_1585304_1	311424.DhcVS_881	4.498e-30	133.0	COG0348@1|root,COG0348@2|Bacteria,2GB0I@200795|Chloroflexi,34DPT@301297|Dehalococcoidia	301297|Dehalococcoidia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
MMD2_k127_1585304_4	1088721.NSU_2830	8.558e-09	64.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1585304_2	443143.GM18_1329	1.889e-12	71.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
MMD2_k127_1585304_5	469371.Tbis_0946	0.0002357	51.0	COG1309@1|root,COG1309@2|Bacteria,2GM0B@201174|Actinobacteria,4E5FT@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMD2_k127_1585304_0	709797.CSIRO_1946	1.703e-61	218.0	COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,2U5JQ@28211|Alphaproteobacteria,3JY1B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	pcaC	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMD2_k127_1589031_25	396588.Tgr7_3156	2.72e-41	156.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
MMD2_k127_1589031_27	234267.Acid_4171	2.27e-39	159.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_1589031_13	1157708.KB907460_gene1359	1.459e-95	323.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2VJM3@28216|Betaproteobacteria,4AC1Z@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Methyltransferase type 11	ubiE_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMD2_k127_1589031_20	794846.AJQU01000114_gene4891	1.911e-57	207.0	28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2TU05@28211|Alphaproteobacteria,4BC3I@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	MA20_08580	-	-	-	-	-	-	-	-	-	-	-	Endostatin
MMD2_k127_1589031_34	344747.PM8797T_12478	1.833e-07	63.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
MMD2_k127_1589031_5	1265313.HRUBRA_01849	3.169e-175	572.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ_2
MMD2_k127_1589031_19	715451.ambt_12010	3.758e-62	228.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1589031_33	861299.J421_1875	1.62e-14	80.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
MMD2_k127_1589031_30	644282.Deba_0543	4.459e-29	121.0	2E451@1|root,32Z13@2|Bacteria,1N0RY@1224|Proteobacteria,42UM1@68525|delta/epsilon subdivisions,2WQAD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1589031_14	118005.AWNK01000011_gene94	7.586e-94	316.0	COG5266@1|root,COG5266@2|Bacteria	2|Bacteria	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	DUF4198
MMD2_k127_1589031_12	1419583.V466_30340	3.963e-107	359.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,1RY8W@1236|Gammaproteobacteria,1YPQ7@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
MMD2_k127_1589031_16	526222.Desal_0993	4.013e-71	249.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42UDG@68525|delta/epsilon subdivisions,2WQAB@28221|Deltaproteobacteria,2MAG3@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
MMD2_k127_1589031_11	1121451.DESAM_20780	1.675e-107	367.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2X2BP@28221|Deltaproteobacteria,2M9TC@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
MMD2_k127_1589031_24	1419583.V466_30325	6.154e-48	194.0	COG0803@1|root,COG0803@2|Bacteria,1N69A@1224|Proteobacteria,1SAUM@1236|Gammaproteobacteria,1YM7W@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	P	Zinc-uptake complex component A periplasmic	VPA0165	-	-	-	-	-	-	-	-	-	-	-	ZnuA
MMD2_k127_1589031_8	420662.Mpe_A1451	5.362e-120	400.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2VH8S@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Twin-arginine translocation pathway signal sequence	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,TAT_signal
MMD2_k127_1589031_1	420662.Mpe_A1450	3.498e-205	653.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VJ7P@28216|Betaproteobacteria,1KJDD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
MMD2_k127_1589031_22	1121939.L861_01760	1.289e-54	206.0	COG2128@1|root,COG2128@2|Bacteria,1NDTM@1224|Proteobacteria	1224|Proteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMD2_k127_1589031_18	42345.XP_008792606.1	2.725e-69	249.0	COG3491@1|root,KOG0143@2759|Eukaryota,37JYU@33090|Viridiplantae,3G8XN@35493|Streptophyta,3KUPH@4447|Liliopsida	35493|Streptophyta	Q	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
MMD2_k127_1589031_0	1300345.LF41_3143	4.147e-217	697.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X393@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	-	-	-	-	-	-	-	-	-	-	PALP
MMD2_k127_1589031_2	1121939.L861_01755	8.058e-189	634.0	COG3629@1|root,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria	1224|Proteobacteria	K	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD
MMD2_k127_1589031_31	1121939.L861_01750	1.099e-22	111.0	2C1W2@1|root,31MWG@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
MMD2_k127_1589031_15	1040982.AXAL01000029_gene4286	3.108e-78	276.0	COG1765@1|root,COG1765@2|Bacteria,1RBJN@1224|Proteobacteria,2VF54@28211|Alphaproteobacteria,43MJG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMD2_k127_1589031_4	1298863.AUEP01000004_gene2260	3.527e-178	572.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4DQ11@85009|Propionibacteriales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
MMD2_k127_1589031_21	78579.XP_003661026.1	5.267e-56	216.0	2EBD3@1|root,2SHGJ@2759|Eukaryota,39TQZ@33154|Opisthokonta,3NZP0@4751|Fungi,3QR77@4890|Ascomycota,218S5@147550|Sordariomycetes,3UABU@5139|Sordariales,3HAHA@35718|Chaetomiaceae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1589031_32	926550.CLDAP_19560	4.232e-16	87.0	2EB0S@1|root,3351M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1589031_23	1384056.N787_09940	2.849e-50	184.0	COG1247@1|root,COG1247@2|Bacteria,1QUGY@1224|Proteobacteria,1T1YJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yhhY	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
MMD2_k127_1589031_6	1123020.AUIE01000005_gene4241	1.801e-168	544.0	COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,1RNNT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD linked oxidase domain protein	-	-	1.17.99.1	ko:K05797	ko00623,ko01100,ko01120,map00623,map01100,map01120	-	R02675,R11194	RC00769	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMD2_k127_1589031_10	1122604.JONR01000003_gene1528	1.275e-107	358.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,1SC01@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
MMD2_k127_1589031_9	685778.AORL01000021_gene797	2.235e-110	363.0	COG2133@1|root,COG2133@2|Bacteria,1R6DX@1224|Proteobacteria,2U562@28211|Alphaproteobacteria,2K1D2@204457|Sphingomonadales	204457|Sphingomonadales	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
MMD2_k127_1589031_17	991905.SL003B_3169	7.624e-70	246.0	COG3473@1|root,COG3473@2|Bacteria,1RA2D@1224|Proteobacteria,2U5UC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Asp Glu hydantoin racemase	-	-	4.1.1.76,5.2.1.1	ko:K01799,ko:K06033	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
MMD2_k127_1589031_28	1173021.ALWA01000032_gene1085	2.993e-32	142.0	COG2885@1|root,COG2885@2|Bacteria,1G8PB@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMD2_k127_1589031_3	1095769.CAHF01000011_gene2568	5.177e-183	608.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS,PAS_3
MMD2_k127_1589031_26	247633.GP2143_17796	4.902e-40	166.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1616233_8	1238182.C882_2899	5.676e-149	479.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,2TWD4@28211|Alphaproteobacteria,2JPB7@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
MMD2_k127_1616233_49	316067.Geob_2596	7.907e-08	61.0	COG2133@1|root,COG3292@1|root,COG4733@1|root,COG2133@2|Bacteria,COG3292@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	CHB_HEX_C_1,DUF1906,Malectin,fn3
MMD2_k127_1616233_23	589865.DaAHT2_1412	2.818e-101	342.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2MIA7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
MMD2_k127_1616233_44	1216007.AOPM01000073_gene1348	5.411e-22	104.0	COG0747@1|root,COG3637@1|root,COG4625@1|root,COG0747@2|Bacteria,COG3637@2|Bacteria,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,1T3XP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	outer membrane autotransporter barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
MMD2_k127_1616233_35	323261.Noc_1987	5.93e-66	253.0	COG0457@1|root,COG5010@1|root,COG0457@2|Bacteria,COG5010@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1WX0E@135613|Chromatiales	135613|Chromatiales	U	PEP-CTERM system TPR-repeat lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
MMD2_k127_1616233_2	396588.Tgr7_2339	1.014e-211	665.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1WX6X@135613|Chromatiales	135613|Chromatiales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMD2_k127_1616233_17	472759.Nhal_3271	2.125e-124	413.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1WWWA@135613|Chromatiales	135613|Chromatiales	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
MMD2_k127_1616233_16	765910.MARPU_05390	3.699e-125	426.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,1WWAJ@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c
MMD2_k127_1616233_38	1380394.JADL01000008_gene3654	1.222e-60	216.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2U835@28211|Alphaproteobacteria,2JS6A@204441|Rhodospirillales	204441|Rhodospirillales	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
MMD2_k127_1616233_24	519989.ECTPHS_06357	5.186e-95	331.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria,1WWGP@135613|Chromatiales	135613|Chromatiales	M	Polysaccharide chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
MMD2_k127_1616233_34	765910.MARPU_05410	4.504e-66	241.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1WWGG@135613|Chromatiales	135613|Chromatiales	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
MMD2_k127_1616233_46	519989.ECTPHS_06367	4.067e-14	85.0	COG5338@1|root,COG5338@2|Bacteria,1RHNA@1224|Proteobacteria,1SBMV@1236|Gammaproteobacteria,1WWU4@135613|Chromatiales	135613|Chromatiales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
MMD2_k127_1616233_22	1158762.KB898054_gene71	1.184e-101	340.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,1WWEV@135613|Chromatiales	135613|Chromatiales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
MMD2_k127_1616233_39	1000565.METUNv1_03757	1.09e-58	226.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VMAH@28216|Betaproteobacteria,2KUGS@206389|Rhodocyclales	206389|Rhodocyclales	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
MMD2_k127_1616233_15	765911.Thivi_4253	3.86e-127	417.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,1T22W@1236|Gammaproteobacteria,1X2NU@135613|Chromatiales	135613|Chromatiales	V	TIGRFAM FemAB-related protein, PEP-CTERM system-associated	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
MMD2_k127_1616233_1	1454004.AW11_02201	1.187e-224	713.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
MMD2_k127_1616233_10	62928.azo3270	7.291e-145	471.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,2KUCI@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4
MMD2_k127_1616233_5	62928.azo3269	1.904e-166	533.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VMX7@28216|Betaproteobacteria,2KYAE@206389|Rhodocyclales	206389|Rhodocyclales	C	UDP binding domain	algD	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMD2_k127_1616233_12	757424.Hsero_2750	7.975e-134	437.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VHM2@28216|Betaproteobacteria,473I4@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMD2_k127_1616233_18	85643.Tmz1t_3273	4.517e-116	387.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,2KUXN@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMD2_k127_1616233_0	1454004.AW11_02203	2.095e-307	955.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Asparagine synthase	asnB1	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
MMD2_k127_1616233_21	1288494.EBAPG3_29310	6.724e-105	358.0	COG0438@1|root,COG0438@2|Bacteria,1R2WM@1224|Proteobacteria,2VKPJ@28216|Betaproteobacteria,372ND@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMD2_k127_1616233_32	1158762.KB898049_gene744	2.921e-74	257.0	COG2227@1|root,COG2227@2|Bacteria,1NN8A@1224|Proteobacteria,1SGKE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMD2_k127_1616233_26	62928.azo3266	1.391e-93	317.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2VIWN@28216|Betaproteobacteria,2KVT6@206389|Rhodocyclales	206389|Rhodocyclales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMD2_k127_1616233_37	879212.DespoDRAFT_01657	1.344e-61	227.0	COG3919@1|root,COG3919@2|Bacteria	2|Bacteria	E	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
MMD2_k127_1616233_33	291112.PAU_00141	1.627e-68	243.0	2DWN5@1|root,3414V@2|Bacteria	2|Bacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
MMD2_k127_1616233_31	1219084.AP014508_gene878	4.338e-76	276.0	COG0367@1|root,COG0367@2|Bacteria,2GE6X@200918|Thermotogae	200918|Thermotogae	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	-
MMD2_k127_1616233_47	1120953.AUBH01000016_gene2839	1.489e-08	63.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,46729@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
MMD2_k127_1616233_11	879212.DespoDRAFT_01658	1.027e-143	470.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2MJBU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
MMD2_k127_1616233_4	323848.Nmul_A2668	5.553e-171	556.0	COG0367@1|root,COG0367@2|Bacteria,1PRFK@1224|Proteobacteria,2VJKQ@28216|Betaproteobacteria,371T9@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Asparagine synthase	asnB2	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
MMD2_k127_1616233_25	76114.ebA4291	1.184e-93	314.0	COG2227@1|root,COG2227@2|Bacteria,1QVIA@1224|Proteobacteria,2VWHZ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMD2_k127_1616233_50	1123250.KB908383_gene1380	7.07e-07	55.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	2.3.3.1	ko:K01647,ko:K02078	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PP-binding
MMD2_k127_1616233_28	1307759.JOMJ01000003_gene1984	5.734e-90	321.0	COG3882@1|root,COG3882@2|Bacteria,1PNPC@1224|Proteobacteria,42QNY@68525|delta/epsilon subdivisions,2WU41@28221|Deltaproteobacteria,2M7S2@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	HAD-superfamily phosphatase subfamily IIIC	-	-	-	-	-	-	-	-	-	-	-	-	NIF
MMD2_k127_1616233_41	113395.AXAI01000006_gene1550	1.135e-43	171.0	COG2746@1|root,COG2746@2|Bacteria,1NBKU@1224|Proteobacteria,2UKEP@28211|Alphaproteobacteria,3K22A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
MMD2_k127_1616233_27	1121451.DESAM_20915	1.849e-91	319.0	COG1028@1|root,COG2030@1|root,COG1028@2|Bacteria,COG2030@2|Bacteria,1Q55V@1224|Proteobacteria,430M5@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMD2_k127_1616233_36	335283.Neut_0902	3.709e-62	226.0	COG0726@1|root,COG0726@2|Bacteria,1RAPZ@1224|Proteobacteria,2WFKR@28216|Betaproteobacteria,374PZ@32003|Nitrosomonadales	28216|Betaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1616233_13	1415778.JQMM01000001_gene319	1.831e-128	424.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,1SZKU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMD2_k127_1616233_14	1248760.ANFZ01000018_gene664	2.031e-127	424.0	COG1524@1|root,COG1524@2|Bacteria,1MV1X@1224|Proteobacteria,2UP59@28211|Alphaproteobacteria,2K9CY@204457|Sphingomonadales	204457|Sphingomonadales	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1616233_29	864051.BurJ1DRAFT_3163	3.278e-88	306.0	COG0438@1|root,COG0438@2|Bacteria,1PVZ8@1224|Proteobacteria,2VPK3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4
MMD2_k127_1616233_42	1198452.Jab_2c08280	2.751e-36	147.0	COG0457@1|root,COG0457@2|Bacteria,1RIHH@1224|Proteobacteria,2VTBB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2
MMD2_k127_1616233_20	1192034.CAP_6852	1.692e-109	374.0	2DBH8@1|root,2Z982@2|Bacteria,1MXUE@1224|Proteobacteria	1224|Proteobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
MMD2_k127_1616233_43	324602.Caur_3440	6.956e-24	112.0	COG2227@1|root,COG2227@2|Bacteria,2GAEK@200795|Chloroflexi,376X5@32061|Chloroflexia	32061|Chloroflexia	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMD2_k127_1616233_19	338969.Rfer_0691	5.117e-114	384.0	COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,2WEWR@28216|Betaproteobacteria,4AJNX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
MMD2_k127_1616233_40	316067.Geob_2959	6.95e-50	192.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	lpsE	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glyphos_transf
MMD2_k127_1616233_3	670307.HYPDE_29643	5.333e-183	596.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,3N7HK@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
MMD2_k127_1616233_7	1286093.C266_25085	2.374e-158	522.0	COG3882@1|root,COG3882@2|Bacteria,1PNPC@1224|Proteobacteria,2VQVT@28216|Betaproteobacteria,1K0JQ@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	HAD-superfamily phosphatase subfamily IIIC	-	-	-	-	-	-	-	-	-	-	-	-	NIF
MMD2_k127_1616233_45	682795.AciX8_1166	1.457e-14	76.0	COG0236@1|root,COG0236@2|Bacteria,3Y5X4@57723|Acidobacteria,2JK2V@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	-
MMD2_k127_1616233_6	1500894.JQNN01000001_gene783	4.889e-164	533.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2VISD@28216|Betaproteobacteria,475GY@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	MBOAT, membrane-bound O-acyltransferase family	pacA	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
MMD2_k127_1616233_9	1095769.CAHF01000010_gene1300	5.259e-147	470.0	COG1216@1|root,COG1216@2|Bacteria,1N0WW@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD2_k127_1616233_48	33876.JNXY01000006_gene920	5.371e-08	64.0	COG0463@1|root,COG0463@2|Bacteria,2I0YU@201174|Actinobacteria,4D8W1@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD2_k127_1616233_30	1095769.CAHF01000010_gene1301	1.956e-80	273.0	2ART5@1|root,31H4G@2|Bacteria,1R86P@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1626999_3	1035191.HMPREF0185_00026	1.969e-117	386.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,2KF9Z@204458|Caulobacterales	204458|Caulobacterales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMD2_k127_1626999_0	1234364.AMSF01000013_gene668	7.28e-207	657.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1X3KZ@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
MMD2_k127_1626999_7	290397.Adeh_1979	7.081e-74	254.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42QN7@68525|delta/epsilon subdivisions,2WP27@28221|Deltaproteobacteria,2YVXG@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
MMD2_k127_1626999_2	383372.Rcas_1546	8.938e-126	422.0	COG0473@1|root,COG0473@2|Bacteria,2G63C@200795|Chloroflexi,3755M@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMD2_k127_1626999_8	666685.R2APBS1_1363	1.096e-28	117.0	COG4496@1|root,COG4496@2|Bacteria,1NAAX@1224|Proteobacteria,1SG3S@1236|Gammaproteobacteria,1X7DY@135614|Xanthomonadales	135614|Xanthomonadales	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
MMD2_k127_1626999_5	1123073.KB899242_gene1406	6.677e-95	319.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1X4SF@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
MMD2_k127_1626999_1	1500893.JQNB01000001_gene2016	3.321e-147	492.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1X4GX@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
MMD2_k127_1626999_6	1163408.UU9_15822	2.771e-82	295.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1X3SR@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_1626999_4	1234364.AMSF01000016_gene1670	1.131e-102	347.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1X38F@135614|Xanthomonadales	135614|Xanthomonadales	E	Histidine biosynthesis bifunctional protein HisB	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
MMD2_k127_1637345_16	452637.Oter_4159	9.144e-55	206.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_1637345_17	67356.KL575637_gene5307	2.381e-52	198.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
MMD2_k127_1637345_4	1535287.JP74_04850	3.144e-144	465.0	COG3836@1|root,COG3836@2|Bacteria,1P861@1224|Proteobacteria	1224|Proteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
MMD2_k127_1637345_23	525257.HMPREF0204_13314	6.811e-26	115.0	COG3548@1|root,COG3548@2|Bacteria,4NSYF@976|Bacteroidetes,1I6GM@117743|Flavobacteriia,3ZQ2D@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
MMD2_k127_1637345_30	1336235.JAEG01000002_gene300	0.0003561	48.0	2DPG2@1|root,32UM0@2|Bacteria,1N4US@1224|Proteobacteria,2UX1A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1637345_6	1156937.MFUM_290002	1.445e-130	436.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,37G39@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine protease	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMD2_k127_1637345_1	187272.Mlg_0596	3.272e-164	529.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1WVW6@135613|Chromatiales	135613|Chromatiales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
MMD2_k127_1637345_12	1437882.AZRU01000006_gene1579	6.939e-87	301.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1YDPR@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
MMD2_k127_1637345_24	1283300.ATXB01000001_gene1611	4.003e-25	114.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1XF0Z@135618|Methylococcales	135618|Methylococcales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
MMD2_k127_1637345_3	396588.Tgr7_2048	7.288e-160	518.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1WWGZ@135613|Chromatiales	135613|Chromatiales	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
MMD2_k127_1637345_27	1453501.JELR01000001_gene3016	1.709e-15	88.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,4689I@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	rodZ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
MMD2_k127_1637345_18	1026882.MAMP_00049	6.057e-49	184.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,460N9@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_2,TPR_8
MMD2_k127_1637345_7	472759.Nhal_1092	3.889e-124	410.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1WWD4@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
MMD2_k127_1637345_13	243233.MCA2886	8.215e-69	235.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1XEZG@135618|Methylococcales	135618|Methylococcales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
MMD2_k127_1637345_20	747.DR93_1094	5.215e-41	153.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1Y8WG@135625|Pasteurellales	135625|Pasteurellales	C	Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
MMD2_k127_1637345_29	334545.CCMG01000007_gene267	3.644e-06	54.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2TU34@28211|Alphaproteobacteria,47F8P@766|Rickettsiales	766|Rickettsiales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMD2_k127_1637345_9	864051.BurJ1DRAFT_1010	1.805e-113	385.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,1KJQM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
MMD2_k127_1637345_14	519989.ECTPHS_12788	5.97e-67	237.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1WVWE@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
MMD2_k127_1637345_10	765911.Thivi_3149	5.818e-93	317.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales	135613|Chromatiales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
MMD2_k127_1637345_0	1283300.ATXB01000001_gene1856	2.562e-175	570.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1XDXB@135618|Methylococcales	135618|Methylococcales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
MMD2_k127_1637345_22	1300345.LF41_555	8.425e-30	123.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1X7J1@135614|Xanthomonadales	135614|Xanthomonadales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
MMD2_k127_1637345_2	519989.ECTPHS_05521	1.651e-160	516.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1WWQ8@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
MMD2_k127_1637345_5	519989.ECTPHS_05526	7.731e-134	434.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales	135613|Chromatiales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
MMD2_k127_1637345_26	1123073.KB899241_gene1794	2.22e-23	111.0	COG0265@1|root,COG0265@2|Bacteria,1PCJA@1224|Proteobacteria,1SXM8@1236|Gammaproteobacteria,1X6DM@135614|Xanthomonadales	135614|Xanthomonadales	O	PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
MMD2_k127_1637345_21	1123253.AUBD01000005_gene128	1.252e-35	142.0	COG1595@1|root,COG1595@2|Bacteria,1QDHS@1224|Proteobacteria,1SS07@1236|Gammaproteobacteria,1X6DE@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_1637345_25	288000.BBta_2401	5.695e-25	115.0	COG2259@1|root,COG2259@2|Bacteria,1RCKY@1224|Proteobacteria,2U6KP@28211|Alphaproteobacteria,3JYKN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
MMD2_k127_1637345_11	472759.Nhal_3599	2.496e-92	309.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,1WY65@135613|Chromatiales	135613|Chromatiales	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
MMD2_k127_1637345_15	1123257.AUFV01000010_gene3293	7.461e-56	214.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1X3T4@135614|Xanthomonadales	135614|Xanthomonadales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
MMD2_k127_1637345_8	911239.CF149_00912	3.682e-118	387.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	recombinase XerD	xerD	GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMD2_k127_1637345_19	388051.AUFE01000051_gene3017	6.997e-42	163.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,1KG5N@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	amp-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,Acyltransferase,PP-binding
MMD2_k127_1647297_3	1279017.AQYJ01000022_gene2618	4.927e-16	92.0	2C612@1|root,32RGH@2|Bacteria,1RGYZ@1224|Proteobacteria,1S8MM@1236|Gammaproteobacteria,46BBZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1647297_0	1280949.HAD_14109	7.58e-284	883.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	MA20_01050	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Fer4_7,NADH_4Fe-4S,Pyr_redox_2,Pyr_redox_3
MMD2_k127_1647297_1	1280953.HOC_18124	5.593e-272	848.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,43Z43@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	pyruvate flavodoxin ferredoxin oxidoreductase	MA20_01045	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
MMD2_k127_1647297_2	1379270.AUXF01000003_gene3543	2.806e-144	470.0	COG1013@1|root,COG1013@2|Bacteria,1ZSWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMD2_k127_165436_14	357808.RoseRS_1962	5.259e-102	338.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,3753Z@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMD2_k127_165436_10	715226.ABI_27820	6.234e-132	429.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,2KF0A@204458|Caulobacterales	204458|Caulobacterales	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
MMD2_k127_165436_25	1331060.RLDS_10585	1.006e-65	228.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,2K3WE@204457|Sphingomonadales	204457|Sphingomonadales	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
MMD2_k127_165436_19	518766.Rmar_0188	1.431e-84	289.0	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes	976|Bacteroidetes	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
MMD2_k127_165436_6	1123073.KB899241_gene2699	2.158e-149	483.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1X32P@135614|Xanthomonadales	135614|Xanthomonadales	E	aminotransferase	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_165436_22	1123257.AUFV01000002_gene2640	3.79e-72	273.0	COG3857@1|root,COG3857@2|Bacteria,1QUQD@1224|Proteobacteria,1T20Z@1236|Gammaproteobacteria,1X7NW@135614|Xanthomonadales	135614|Xanthomonadales	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
MMD2_k127_165436_2	1123261.AXDW01000006_gene2409	2.125e-225	737.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1X3M3@135614|Xanthomonadales	135614|Xanthomonadales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
MMD2_k127_165436_46	323850.Shew_3609	1.741e-12	77.0	2CBG9@1|root,32RTB@2|Bacteria,1R86M@1224|Proteobacteria,1RNNN@1236|Gammaproteobacteria,2QB1Y@267890|Shewanellaceae	1236|Gammaproteobacteria	S	type II secretion system protein N	gspN	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSN
MMD2_k127_165436_48	1123257.AUFV01000001_gene1930	6.264e-11	75.0	COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1T8T9@1236|Gammaproteobacteria,1X7ZW@135614|Xanthomonadales	135614|Xanthomonadales	U	Type II secretion system (T2SS), protein M	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM
MMD2_k127_165436_47	2340.JV46_18960	5.03e-11	75.0	COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,1JB3D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	gspL	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
MMD2_k127_165436_27	395493.BegalDRAFT_3088	3.41e-64	240.0	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,460PF@72273|Thiotrichales	72273|Thiotrichales	U	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
MMD2_k127_165436_38	1049564.TevJSym_av00310	3.959e-34	140.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1J79H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	General secretion pathway protein J	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
MMD2_k127_165436_45	653733.Selin_0057	2.135e-15	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	lspI	-	-	ko:K02246,ko:K02456,ko:K02457,ko:K02458	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
MMD2_k127_165436_43	1499686.BN1079_02666	1.106e-19	98.0	COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein h	gspH	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
MMD2_k127_165436_33	765914.ThisiDRAFT_1920	2.934e-45	173.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1WY8U@135613|Chromatiales	135613|Chromatiales	U	general secretion pathway protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
MMD2_k127_165436_40	391615.ABSJ01000050_gene1175	1.534e-30	136.0	COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMD2_k127_165436_16	1123399.AQVE01000013_gene284	7.008e-90	312.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,45ZWN@72273|Thiotrichales	72273|Thiotrichales	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMD2_k127_165436_41	1268635.Loa_01127	1.967e-30	123.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1JEY0@118969|Legionellales	118969|Legionellales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
MMD2_k127_165436_4	1163407.UU7_02852	7.051e-183	580.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1X3AN@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMD2_k127_165436_23	472759.Nhal_3120	1.453e-70	247.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1WXUQ@135613|Chromatiales	135613|Chromatiales	EH	PFAM Aminotransferase, class IV	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
MMD2_k127_165436_15	1049564.TevJSym_bc00190	1.154e-99	335.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1J56S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
MMD2_k127_165436_26	1049564.TevJSym_bc00200	6.542e-65	228.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1J5UI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c13120,ic_1306.c1370	Thymidylate_kin
MMD2_k127_165436_37	380358.XALC_0632	1.172e-34	151.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1X34V@135614|Xanthomonadales	135614|Xanthomonadales	L	the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
MMD2_k127_165436_31	1123257.AUFV01000001_gene1911	2.312e-48	177.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1X6W7@135614|Xanthomonadales	135614|Xanthomonadales	NU	Pilus assembly protein PilZ	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
MMD2_k127_165436_13	391615.ABSJ01000026_gene110	4.724e-105	351.0	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	PT	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
MMD2_k127_165436_3	1283300.ATXB01000002_gene3073	2.269e-208	667.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XEFK@135618|Methylococcales	135618|Methylococcales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1
MMD2_k127_165436_20	1121405.dsmv_2076	5.316e-80	277.0	COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,42QPA@68525|delta/epsilon subdivisions,2WMPU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
MMD2_k127_165436_44	203119.Cthe_2456	2.774e-17	87.0	arCOG06471@1|root,32BPX@2|Bacteria,1VD13@1239|Firmicutes,24M2I@186801|Clostridia	186801|Clostridia	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
MMD2_k127_165436_18	1225785.CM001983_gene3276	7.556e-87	297.0	COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,2JD7V@204037|Dickeya	1236|Gammaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119	GDPD
MMD2_k127_165436_29	1415780.JPOG01000001_gene116	1.173e-54	203.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1X48E@135614|Xanthomonadales	135614|Xanthomonadales	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
MMD2_k127_165436_51	1268635.Loa_02891	4.836e-05	53.0	2C256@1|root,2Z7SY@2|Bacteria,1Q75P@1224|Proteobacteria,1RPCR@1236|Gammaproteobacteria,1JDVJ@118969|Legionellales	118969|Legionellales	M	Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors	pagP	-	2.3.1.251	ko:K12973	ko01503,ko05133,map01503,map05133	M00724	R11223	RC00037,RC00041	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PagP
MMD2_k127_165436_0	314278.NB231_14788	4.027e-235	744.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
MMD2_k127_165436_17	1254432.SCE1572_09255	8.025e-88	307.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
MMD2_k127_165436_11	349521.HCH_02013	5.51e-126	409.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
MMD2_k127_165436_39	1122603.ATVI01000005_gene3013	9.756e-33	140.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1X3KB@135614|Xanthomonadales	135614|Xanthomonadales	O	Cytochrome C biogenesis	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19,TPR_2
MMD2_k127_165436_36	1042375.AFPL01000017_gene358	2.629e-35	145.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,467TB@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	subunit of a heme lyase	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567	-	ko:K02200,ko:K04017	-	-	-	-	ko00000	-	-	-	CcmH
MMD2_k127_165436_30	1049564.TevJSym_ad01650	8.149e-52	192.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1J634@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
MMD2_k127_165436_1	640081.Dsui_1172	5.914e-229	729.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,2KUNW@206389|Rhodocyclales	206389|Rhodocyclales	O	Cytochrome c	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
MMD2_k127_165436_32	420662.Mpe_A1212	1.713e-46	174.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,1KKY8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
MMD2_k127_165436_52	1504981.KO116_0245	0.0001185	49.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,1SGGH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmD	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735	CcmD
MMD2_k127_165436_21	323261.Noc_0946	9.534e-77	264.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1WX10@135613|Chromatiales	135613|Chromatiales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
MMD2_k127_165436_28	1301098.PKB_1698	7.922e-55	209.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECO111_1330.ECO111_2936,iYL1228.KPN_02080	CcmB
MMD2_k127_165436_35	1380391.JIAS01000018_gene899	6.717e-39	155.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,2JRQJ@204441|Rhodospirillales	204441|Rhodospirillales	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
MMD2_k127_165436_50	1121035.AUCH01000003_gene1191	2.09e-07	63.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VMD2@28216|Betaproteobacteria,2KVQP@206389|Rhodocyclales	206389|Rhodocyclales	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
MMD2_k127_165436_49	1123487.KB892840_gene99	7.103e-09	68.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMD2_k127_165436_34	1033802.SSPSH_002140	2.632e-41	162.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_165436_5	1038859.AXAU01000001_gene2708	7.067e-162	516.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,3JV8Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
MMD2_k127_165436_9	861299.J421_5942	4.259e-135	441.0	COG0709@1|root,COG0709@2|Bacteria	2|Bacteria	E	selenide, water dikinase activity	selD	GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	iPC815.YPO2164,iSFV_1184.SFV_1453,iSF_1195.SF1459,iSFxv_1172.SFxv_1645,iS_1188.S1574	AIRS,AIRS_C
MMD2_k127_165436_24	1028801.RG1141_PA00180	2.307e-66	238.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2USHI@28211|Alphaproteobacteria,4BBXA@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMD2_k127_165436_12	1342301.JASD01000008_gene2691	3.627e-120	407.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,3ZV2R@60136|Sulfitobacter	28211|Alphaproteobacteria	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
MMD2_k127_165436_8	1096546.WYO_1945	2.21e-137	464.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,2TUFY@28211|Alphaproteobacteria,1JT30@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
MMD2_k127_165436_42	1028800.RG540_PA00200	8.882e-20	92.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,4BBRG@82115|Rhizobiaceae	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMD2_k127_165436_7	935840.JAEQ01000020_gene2336	3.141e-142	464.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMD2_k127_1686517_27	349124.Hhal_2328	6.686e-24	103.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1WY2S@135613|Chromatiales	135613|Chromatiales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
MMD2_k127_1686517_4	1122138.AQUZ01000002_gene2132	2.074e-161	548.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DSSQ@85009|Propionibacteriales	201174|Actinobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8,fn3_5
MMD2_k127_1686517_17	879212.DespoDRAFT_02506	6.871e-77	263.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MJGI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
MMD2_k127_1686517_15	187272.Mlg_2825	1.177e-82	285.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1WW5V@135613|Chromatiales	135613|Chromatiales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
MMD2_k127_1686517_11	246197.MXAN_3558	1.414e-104	376.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2YVGD@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMD2_k127_1686517_6	187272.Mlg_2534	4.128e-155	501.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMD2_k127_1686517_2	1049564.TevJSym_ak00380	6.328e-218	700.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1J572@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Oligopeptidase A	prlC	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
MMD2_k127_1686517_13	684949.ATTJ01000003_gene3235	1.185e-98	329.0	COG0708@1|root,COG0708@2|Bacteria,1WMBY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
MMD2_k127_1686517_16	391615.ABSJ01000026_gene121	8.79e-82	285.0	2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria,1J8X1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1686517_26	136993.KB900627_gene391	8.121e-32	129.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1686517_28	247633.GP2143_18121	1.244e-23	111.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1686517_0	467661.RKLH11_3654	0.0	2636.0	COG4625@1|root,COG4625@2|Bacteria,1N4H5@1224|Proteobacteria,2TT5A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	outer membrane autotransporter barrel	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
MMD2_k127_1686517_7	639283.Snov_1592	4.013e-130	441.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria,3EZS5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMD2_k127_1686517_19	1121939.L861_23570	1.632e-66	233.0	COG1309@1|root,COG1309@2|Bacteria,1RFK1@1224|Proteobacteria,1S5KJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMD2_k127_1686517_12	1395571.TMS3_0113540	3.824e-103	346.0	COG1566@1|root,COG1566@2|Bacteria,1RBK7@1224|Proteobacteria,1S241@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	multidrug resistance efflux pump	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMD2_k127_1686517_8	1215092.PA6_005_01120	2.4e-128	432.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1YFAZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ybhF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_1686517_5	1121939.L861_23585	2.551e-157	514.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1XHBH@135619|Oceanospirillales	135619|Oceanospirillales	U	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMD2_k127_1686517_23	342113.DM82_4181	3.846e-42	161.0	COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,2VV7K@28216|Betaproteobacteria,1KHF4@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_1686517_10	1254432.SCE1572_28155	1.244e-109	363.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,42RC6@68525|delta/epsilon subdivisions,2WN72@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	transcription activator, effector binding	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
MMD2_k127_1686517_18	330214.NIDE0757	2.534e-71	247.0	COG0770@1|root,COG0770@2|Bacteria,3J0PW@40117|Nitrospirae	40117|Nitrospirae	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMD2_k127_1686517_14	330214.NIDE0757	8.24e-86	293.0	COG0770@1|root,COG0770@2|Bacteria,3J0PW@40117|Nitrospirae	40117|Nitrospirae	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMD2_k127_1686517_3	1242864.D187_009651	1.107e-161	523.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria,2YWE7@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N,Glyco_hydro_2
MMD2_k127_1686517_24	404589.Anae109_0599	9.661e-42	174.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase	pgl	-	2.7.1.12,3.1.1.31	ko:K00851,ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R01737,R02035	RC00002,RC00017,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
MMD2_k127_1686517_29	640511.BC1002_4150	1.31e-23	117.0	COG2010@1|root,COG2010@2|Bacteria,1N9X8@1224|Proteobacteria,2W3XT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMD2_k127_1686517_1	1123020.AUIE01000005_gene4241	4.539e-280	870.0	COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,1RNNT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD linked oxidase domain protein	-	-	1.17.99.1	ko:K05797	ko00623,ko01100,ko01120,map00623,map01100,map01120	-	R02675,R11194	RC00769	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMD2_k127_1686517_9	290400.Jann_3479	4.313e-116	386.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	EHN
MMD2_k127_1686517_25	1395571.TMS3_0100965	3.235e-37	143.0	COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
MMD2_k127_1686517_32	1108045.GORHZ_055_00470	1.784e-09	63.0	2FJQ4@1|root,34BD5@2|Bacteria,2GU4Y@201174|Actinobacteria,4GF3N@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
MMD2_k127_1686517_31	1121013.P873_09570	2.54e-16	90.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
MMD2_k127_1686517_21	1122604.JONR01000010_gene3877	1.719e-55	198.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,1X72V@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMD2_k127_1686517_22	1297742.A176_06772	1.35e-48	181.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,434AF@68525|delta/epsilon subdivisions,2X23S@28221|Deltaproteobacteria,2YVSR@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
MMD2_k127_1686517_20	443143.GM18_1301	1.024e-56	210.0	2B64P@1|root,31Z1K@2|Bacteria,1RGUR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1686517_33	293826.Amet_2241	4.08e-08	59.0	COG3981@1|root,COG3981@2|Bacteria,1VA6C@1239|Firmicutes,24HZ2@186801|Clostridia,36INJ@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMD2_k127_1690724_2	1340493.JNIF01000003_gene3475	7.729e-110	372.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_1690724_4	1123242.JH636436_gene366	1.733e-51	187.0	COG5649@1|root,COG5649@2|Bacteria,2IYNG@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
MMD2_k127_1690724_0	251221.35211765	2.452e-169	562.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_1690724_3	279238.Saro_1865	4.232e-59	211.0	COG0346@1|root,COG0346@2|Bacteria,1MWHG@1224|Proteobacteria,2U1WR@28211|Alphaproteobacteria,2K70M@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
MMD2_k127_1690724_5	1085623.GNIT_0678	8.284e-35	141.0	29XEE@1|root,30J4K@2|Bacteria,1P813@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1690724_1	640081.Dsui_1429	4.879e-124	419.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV9J@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,dCache_1
MMD2_k127_1690724_6	234267.Acid_4830	3.121e-06	59.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1732280_0	1292034.OR37_03450	2.829e-311	975.0	COG4772@1|root,COG4772@2|Bacteria,1MXJU@1224|Proteobacteria,2TRYT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_1732280_2	671143.DAMO_0410	4.272e-260	816.0	COG2060@1|root,COG2060@2|Bacteria,2NP13@2323|unclassified Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAPECO1_1312.APECO1_1369,iECUMN_1333.ECUMN_0780,iYL1228.KPN_00717	KdpA
MMD2_k127_1732280_1	93220.LV28_04765	3.988e-293	919.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,2VH26@28216|Betaproteobacteria,1K1X1@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
MMD2_k127_1732280_4	267608.RSc3384	4.138e-64	227.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,2VQ72@28216|Betaproteobacteria,1K3NK@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
MMD2_k127_1732280_3	1209072.ALBT01000078_gene384	8.898e-109	364.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,1FI82@10|Cellvibrio	1236|Gammaproteobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008152,GO:0009593,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031668,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051606,GO:0051716,GO:0065007,GO:0071214,GO:0071470,GO:0071472,GO:0071496,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
MMD2_k127_1762792_13	1452718.JBOY01000005_gene3322	3.14e-05	48.0	COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	atp synthase	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
MMD2_k127_1762792_5	1278307.KB907012_gene3547	8.566e-86	292.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,2QHM8@267894|Psychromonadaceae	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	ATP-synt_A
MMD2_k127_1762792_12	321846.PS417_28490	1.119e-27	113.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
MMD2_k127_1762792_9	1469245.JFBG01000013_gene1947	3.636e-38	148.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1WYT5@135613|Chromatiales	135613|Chromatiales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
MMD2_k127_1762792_10	1335757.SPICUR_09505	4.913e-38	149.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1WY1N@135613|Chromatiales	135613|Chromatiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
MMD2_k127_1762792_0	765914.ThisiDRAFT_2274	1.292e-257	803.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1WVYR@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
MMD2_k127_1762792_3	349521.HCH_07072	1.497e-112	386.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1XHVC@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
MMD2_k127_1762792_1	870187.Thini_3033	3.141e-240	748.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,46017@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
MMD2_k127_1762792_11	1198232.CYCME_2521	7.595e-38	146.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,460V2@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
MMD2_k127_1762792_8	479434.Sthe_3411	4.907e-49	186.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	MetW,Methyltransf_11,Methyltransf_25,Methyltransf_31
MMD2_k127_1762792_7	861299.J421_0843	4.57e-52	199.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	pqqC	-	1.3.3.11	ko:K06137,ko:K06138	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,PqqD,Radical_SAM,SPASM,TENA_THI-4
MMD2_k127_1762792_6	479434.Sthe_3410	1.977e-54	205.0	COG0500@1|root,COG2890@1|root,COG2226@2|Bacteria,COG2890@2|Bacteria,2G9F9@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1762792_2	1500893.JQNB01000001_gene2146	1.358e-205	651.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,1RPZX@1236|Gammaproteobacteria,1X8CV@135614|Xanthomonadales	135614|Xanthomonadales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD2_k127_1762792_4	1163409.UUA_15233	3.055e-112	374.0	COG0438@1|root,COG0438@2|Bacteria,1MWTJ@1224|Proteobacteria,1S1VB@1236|Gammaproteobacteria,1X59W@135614|Xanthomonadales	135614|Xanthomonadales	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMD2_k127_1762792_14	443143.GM18_1647	3.408e-05	53.0	COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,42PP5@68525|delta/epsilon subdivisions,2WMQR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
MMD2_k127_1836125_2	697282.Mettu_2105	2.028e-131	435.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,1XECF@135618|Methylococcales	135618|Methylococcales	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
MMD2_k127_1836125_5	1458357.BG58_18700	2.156e-60	227.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,1K29G@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_1836125_4	1049564.TevJSym_at00270	2.788e-72	258.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1J4S5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	COG4942 Membrane-bound metallopeptidase	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMD2_k127_1836125_15	555793.WSK_4047	1.882e-14	84.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1836125_16	1340493.JNIF01000003_gene2122	1.882e-14	79.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1836125_3	1415779.JOMH01000001_gene3264	5.694e-97	331.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1X36C@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
MMD2_k127_1836125_7	1123257.AUFV01000011_gene3064	1.44e-54	204.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1XAQ5@135614|Xanthomonadales	135614|Xanthomonadales	S	Divergent polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_2
MMD2_k127_1836125_6	56780.SYN_02005	3.012e-60	228.0	COG2199@1|root,COG3706@2|Bacteria,1RCC4@1224|Proteobacteria,43AED@68525|delta/epsilon subdivisions,2WQS7@28221|Deltaproteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMD2_k127_1836125_14	1123366.TH3_18168	8.44e-15	76.0	2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,2UXGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3012
MMD2_k127_1836125_17	56107.Cylst_2548	8.171e-07	61.0	2E3GU@1|root,32YFI@2|Bacteria,1G9HI@1117|Cyanobacteria,1HP28@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1836125_10	1033802.SSPSH_000617	2.813e-33	131.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMD2_k127_1836125_1	1265313.HRUBRA_01849	1.13e-172	573.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ_2
MMD2_k127_1836125_12	1123072.AUDH01000005_gene1609	3.372e-24	108.0	COG3193@1|root,COG3193@2|Bacteria,1REF5@1224|Proteobacteria,2U5M2@28211|Alphaproteobacteria,2JUF6@204441|Rhodospirillales	204441|Rhodospirillales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
MMD2_k127_1836125_0	935261.JAGL01000001_gene1821	7.767e-258	805.0	COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminomethyltransferase folate-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
MMD2_k127_1836125_11	1198232.CYCME_0404	6.002e-26	113.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,4618P@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMD2_k127_1836125_8	1209072.ALBT01000032_gene2094	2.232e-49	190.0	COG1917@1|root,COG1917@2|Bacteria,1QEE2@1224|Proteobacteria	1224|Proteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,DUF4437
MMD2_k127_1836125_9	247633.GP2143_17796	2.537e-37	155.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1836125_18	1267535.KB906767_gene1181	3.012e-05	50.0	COG0577@1|root,COG0577@2|Bacteria,3Y321@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_1952778_53	1049564.TevJSym_aa02290	1.462e-45	168.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1J58G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
MMD2_k127_1952778_66	768671.ThimaDRAFT_1771	8.432e-23	100.0	COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1WZ9Q@135613|Chromatiales	135613|Chromatiales	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
MMD2_k127_1952778_77	158500.BV97_02459	1.529e-05	52.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
MMD2_k127_1952778_2	748280.NH8B_1377	0.0	1275.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KQCR@206351|Neisseriales	206351|Neisseriales	C	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
MMD2_k127_1952778_34	1288963.ADIS_4363	5.574e-81	284.0	COG1835@1|root,COG1835@2|Bacteria,4NHPE@976|Bacteroidetes,47JWZ@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
MMD2_k127_1952778_48	1267533.KB906738_gene2159	1.886e-55	205.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria,2JJIJ@204432|Acidobacteriia	204432|Acidobacteriia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
MMD2_k127_1952778_35	1198452.Jab_2c14080	5.005e-77	276.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VRIK@28216|Betaproteobacteria,475SI@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
MMD2_k127_1952778_32	1502852.FG94_01363	4.433e-88	311.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2VVN2@28216|Betaproteobacteria,475FY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
MMD2_k127_1952778_10	754476.Q7A_2535	5.145e-167	532.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,460E7@72273|Thiotrichales	72273|Thiotrichales	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD2_k127_1952778_20	765912.Thimo_2640	2.055e-119	401.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales	135613|Chromatiales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
MMD2_k127_1952778_27	1224318.DT73_06230	4.017e-101	340.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	cysB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
MMD2_k127_1952778_28	1163408.UU9_11014	2.186e-95	319.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,1X4PS@135614|Xanthomonadales	135614|Xanthomonadales	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
MMD2_k127_1952778_33	551275.KB899544_gene886	3.202e-83	299.0	COG1231@1|root,COG1231@2|Bacteria,1MWPH@1224|Proteobacteria,2U05G@28211|Alphaproteobacteria,43YUX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMD2_k127_1952778_23	344747.PM8797T_16917	1.311e-112	387.0	COG0276@1|root,COG0276@2|Bacteria,2IX75@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
MMD2_k127_1952778_39	926550.CLDAP_19070	1.06e-70	256.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
MMD2_k127_1952778_29	604331.AUHY01000020_gene1908	2.698e-94	319.0	COG0407@1|root,COG0407@2|Bacteria,1WIHR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
MMD2_k127_1952778_36	1122222.AXWR01000028_gene940	9.892e-76	265.0	COG0745@1|root,COG0745@2|Bacteria	1122222.AXWR01000028_gene940|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_54	526227.Mesil_2987	6.848e-38	154.0	COG0642@1|root,COG2205@2|Bacteria,1WM7D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMD2_k127_1952778_15	1236959.BAMT01000007_gene2677	6.887e-129	440.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,2KKPE@206350|Nitrosomonadales	206350|Nitrosomonadales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMD2_k127_1952778_24	644966.Tmar_1259	6.326e-107	359.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,3WCFQ@538999|Clostridiales incertae sedis	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
MMD2_k127_1952778_74	1382356.JQMP01000001_gene829	3.757e-12	79.0	COG1587@1|root,COG1587@2|Bacteria,2GBWA@200795|Chloroflexi,27Z62@189775|Thermomicrobia	189775|Thermomicrobia	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
MMD2_k127_1952778_47	604331.AUHY01000020_gene1913	1.011e-55	215.0	COG0181@1|root,COG0181@2|Bacteria,1WM2C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
MMD2_k127_1952778_56	1122222.AXWR01000028_gene945	5.98e-37	156.0	COG0373@1|root,COG0373@2|Bacteria,1WIN9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
MMD2_k127_1952778_50	1385517.N800_13135	5.958e-49	181.0	2B4XH@1|root,32REP@2|Bacteria,1RJ9F@1224|Proteobacteria,1T0SV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_6	443143.GM18_4034	1.144e-202	664.0	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,42Z0Q@68525|delta/epsilon subdivisions,2WU0G@28221|Deltaproteobacteria,43T6R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_4	1232410.KI421425_gene1549	1.6e-322	1032.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,43CT2@68525|delta/epsilon subdivisions,2X80K@28221|Deltaproteobacteria,43TUA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
MMD2_k127_1952778_52	443143.GM18_4032	1.388e-45	173.0	COG0457@1|root,COG0457@2|Bacteria,1N1J2@1224|Proteobacteria,42ZHG@68525|delta/epsilon subdivisions,2WV2W@28221|Deltaproteobacteria,43UR6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_70	1453501.JELR01000002_gene347	1.299e-16	83.0	2EQ5T@1|root,32ZV0@2|Bacteria,1NFTI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_41	443144.GM21_0442	2.72e-70	245.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2WQK7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
MMD2_k127_1952778_58	1049564.TevJSym_au00050	4.902e-33	134.0	COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,1JAY5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
MMD2_k127_1952778_62	1049564.TevJSym_au00060	7.257e-31	136.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,1JAUR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
MMD2_k127_1952778_37	1385517.N800_13175	1.01e-74	268.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,1X6T0@135614|Xanthomonadales	135614|Xanthomonadales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_1	1385517.N800_13180	0.0	1444.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1QZFW@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
MMD2_k127_1952778_0	1232410.KI421425_gene1552	0.0	1935.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMD2_k127_1952778_75	313606.M23134_07898	2.332e-09	71.0	COG1716@1|root,COG1716@2|Bacteria,4NXUF@976|Bacteroidetes,47WHW@768503|Cytophagia	976|Bacteroidetes	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMD2_k127_1952778_78	105425.BBPL01000013_gene1689	4.073e-05	54.0	2EDJG@1|root,337FB@2|Bacteria,2GTK4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_44	1217718.ALOU01000021_gene2428	6.996e-66	244.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,2VK3I@28216|Betaproteobacteria,1K148@119060|Burkholderiaceae	28216|Betaproteobacteria	P	CBS domain containing protein	clcA_1	-	-	-	-	-	-	-	-	-	-	-	CBS,Voltage_CLC
MMD2_k127_1952778_5	1380394.JADL01000002_gene1729	1.483e-240	777.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2JUZD@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
MMD2_k127_1952778_46	1380394.JADL01000002_gene1730	5.695e-56	201.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2UREX@28211|Alphaproteobacteria,2JWIA@204441|Rhodospirillales	204441|Rhodospirillales	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
MMD2_k127_1952778_26	1123368.AUIS01000033_gene1370	2.49e-103	341.0	COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria	1224|Proteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_1952778_59	290397.Adeh_2888	1.672e-32	135.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_1952778_40	502025.Hoch_5808	1.625e-70	260.0	COG2334@1|root,COG2334@2|Bacteria,1Q18Y@1224|Proteobacteria,42PIW@68525|delta/epsilon subdivisions,2WK5A@28221|Deltaproteobacteria,2YWIH@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMD2_k127_1952778_72	685778.AORL01000024_gene189	1.78e-14	80.0	2EQ70@1|root,33HT9@2|Bacteria,1NIHT@1224|Proteobacteria,2UK3J@28211|Alphaproteobacteria,2K5XI@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_73	1517416.IDAT_09145	2.599e-12	81.0	COG5339@1|root,COG5339@2|Bacteria,1QJ4M@1224|Proteobacteria,1THAV@1236|Gammaproteobacteria,2QGU2@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF945)	-	-	-	-	-	-	-	-	-	-	-	-	DUF945
MMD2_k127_1952778_30	1403819.BATR01000022_gene804	1.022e-90	332.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
MMD2_k127_1952778_9	1121015.N789_06345	1.625e-170	570.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
MMD2_k127_1952778_21	1123261.AXDW01000007_gene2239	7.452e-116	385.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,1RRH7@1236|Gammaproteobacteria,1X430@135614|Xanthomonadales	135614|Xanthomonadales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_1952778_22	1123257.AUFV01000005_gene1321	5.187e-114	381.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,1RPZF@1236|Gammaproteobacteria,1X3MX@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_1952778_25	1122604.JONR01000006_gene2747	7.723e-105	346.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,1X3CK@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	tptC	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_1952778_19	1122604.JONR01000006_gene2746	3.363e-120	400.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,1X3ST@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrE	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMD2_k127_1952778_11	1088721.NSU_3752	4.745e-144	464.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2K3NJ@204457|Sphingomonadales	204457|Sphingomonadales	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
MMD2_k127_1952778_45	1033802.SSPSH_000090	1.003e-58	215.0	COG0730@1|root,COG0730@2|Bacteria,1MVBS@1224|Proteobacteria,1S62V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD2_k127_1952778_18	1121405.dsmv_1218	6.08e-121	391.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,42MR4@68525|delta/epsilon subdivisions,2WM3M@28221|Deltaproteobacteria,2MMW9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
MMD2_k127_1952778_31	411474.COPEUT_02209	2.403e-90	329.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,24DU3@186801|Clostridia	186801|Clostridia	P	TIGRFAM anion transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
MMD2_k127_1952778_17	1128421.JAGA01000003_gene2811	1.439e-121	415.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD2_k127_1952778_14	488538.SAR116_0893	1.173e-129	420.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,4BQDS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	MA20_23235	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
MMD2_k127_1952778_61	313603.FB2170_05370	6.905e-31	127.0	2DNGD@1|root,32XCZ@2|Bacteria,4NSM2@976|Bacteroidetes,1I4Q7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_3	292415.Tbd_0502	0.0	1042.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KS0K@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMD2_k127_1952778_16	292415.Tbd_0501	5.55e-122	399.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,2VMK4@28216|Betaproteobacteria,1KT9E@119069|Hydrogenophilales	119069|Hydrogenophilales	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	-
MMD2_k127_1952778_68	1088721.NSU_2823	2.08e-18	95.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,2KCBM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_8	1049564.TevJSym_cl00010	2.855e-180	576.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1J5GM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
MMD2_k127_1952778_69	640081.Dsui_3382	9.472e-17	91.0	COG0589@1|root,COG0589@2|Bacteria,1PE08@1224|Proteobacteria,2VNHV@28216|Betaproteobacteria,2KVV6@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD2_k127_1952778_65	522306.CAP2UW1_3847	2.566e-24	107.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD2_k127_1952778_12	44251.PDUR_01510	1.438e-142	468.0	COG3118@1|root,COG3118@2|Bacteria,1UI3G@1239|Firmicutes,4ISC1@91061|Bacilli,2770Y@186822|Paenibacillaceae	91061|Bacilli	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
MMD2_k127_1952778_76	1123279.ATUS01000001_gene1708	1.146e-06	58.0	COG5517@1|root,COG5517@2|Bacteria,1N2EN@1224|Proteobacteria,1SDP9@1236|Gammaproteobacteria,1JBPY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_1952778_51	290318.Cvib_1055	1.289e-45	182.0	COG0500@1|root,COG2226@2|Bacteria,1FEKH@1090|Chlorobi	1090|Chlorobi	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMD2_k127_1952778_43	748247.AZKH_4387	6.561e-66	240.0	COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,2VVGP@28216|Betaproteobacteria,2KX6M@206389|Rhodocyclales	206389|Rhodocyclales	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
MMD2_k127_1952778_55	1267535.KB906767_gene227	1.316e-37	150.0	COG1881@1|root,COG1881@2|Bacteria,3Y5UH@57723|Acidobacteria,2JNWC@204432|Acidobacteriia	204432|Acidobacteriia	S	Phosphatidylethanolamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP
MMD2_k127_1952778_57	1223521.BBJX01000019_gene613	2.045e-34	141.0	COG0716@1|root,COG0716@2|Bacteria,1NANK@1224|Proteobacteria,2VW78@28216|Betaproteobacteria,4AHHR@80864|Comamonadaceae	28216|Betaproteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
MMD2_k127_1952778_42	1248916.ANFY01000007_gene2565	6.472e-68	244.0	COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2V788@28211|Alphaproteobacteria,2KBJW@204457|Sphingomonadales	204457|Sphingomonadales	S	hydrolases or acyltransferases, alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_49	870187.Thini_2210	4.26e-52	194.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,1S7MT@1236|Gammaproteobacteria,462U1@72273|Thiotrichales	72273|Thiotrichales	K	Putative FMN-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind_2
MMD2_k127_1952778_13	234267.Acid_5561	1.22e-141	467.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
MMD2_k127_1952778_67	555793.WSK_4047	3.422e-22	111.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_64	1340493.JNIF01000003_gene2122	1.087e-25	111.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_63	136993.KB900627_gene392	1.033e-25	117.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1952778_7	886293.Sinac_1153	3.504e-191	635.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_1952778_38	1267535.KB906767_gene765	3.33e-74	267.0	COG2960@1|root,COG2960@2|Bacteria,3Y7EA@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_1957302_4	1123229.AUBC01000003_gene2010	4.583e-163	519.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2TQJD@28211|Alphaproteobacteria,3JRWI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	yejB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
MMD2_k127_1957302_5	1121033.AUCF01000011_gene1792	6.427e-161	513.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2TR1Y@28211|Alphaproteobacteria,2JPAS@204441|Rhodospirillales	204441|Rhodospirillales	P	transport system, permease component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
MMD2_k127_1957302_1	717785.HYPMC_0625	2.942e-220	695.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,3N6DD@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	yejF	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
MMD2_k127_1957302_19	1045009.AFXQ01000009_gene784	4.602e-06	56.0	COG5517@1|root,COG5517@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_1957302_3	748280.NH8B_1141	7.852e-199	627.0	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2VMQM@28216|Betaproteobacteria,2KSBR@206351|Neisseriales	206351|Neisseriales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_1957302_15	1040982.AXAL01000006_gene381	1.733e-25	108.0	2CYEB@1|root,32T42@2|Bacteria,1MVVN@1224|Proteobacteria,2U2YY@28211|Alphaproteobacteria,43PWX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1957302_16	46234.ANA_C10777	9.095e-11	71.0	COG3751@1|root,COG3751@2|Bacteria,1GHDG@1117|Cyanobacteria	1117|Cyanobacteria	O	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5
MMD2_k127_1957302_12	713586.KB900536_gene2827	5.144e-41	158.0	COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMD2_k127_1957302_11	1131814.JAFO01000001_gene2716	1.889e-42	164.0	COG3932@1|root,COG3932@2|Bacteria,1MZD5@1224|Proteobacteria,2U77X@28211|Alphaproteobacteria,3EZ7J@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
MMD2_k127_1957302_2	1085623.GNIT_3493	4.773e-214	692.0	COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,1RMGX@1236|Gammaproteobacteria,465E9@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG2943 Membrane glycosyltransferase	mdoH	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009628,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016740,GO:0016757,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:1901576	-	ko:K03669	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.3.1.1	GT2	-	Glyco_trans_2_3,Glycos_transf_2
MMD2_k127_1957302_6	1085623.GNIT_3492	2.924e-146	479.0	COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,1RMEB@1236|Gammaproteobacteria,4654Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)	mdoG	GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:1901576	-	ko:K03670	-	-	-	-	ko00000	-	-	-	MdoG
MMD2_k127_1957302_0	1207063.P24_03830	0.0	1256.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,2JP8A@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
MMD2_k127_1957302_10	306281.AJLK01000102_gene3405	1.645e-50	188.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_1957302_9	1280953.HOC_08634	1.484e-63	224.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,43XK1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N,GST_N_2,GST_N_3
MMD2_k127_1957302_7	134676.ACPL_2188	1.815e-142	460.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMD2_k127_1957302_8	134676.ACPL_2189	3.742e-109	372.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4DE6Q@85008|Micromonosporales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMD2_k127_1957302_17	436229.JOEH01000016_gene7280	1.567e-07	63.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,2NHEX@228398|Streptacidiphilus	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMD2_k127_1973602_3	1003200.AXXA_27015	1.921e-110	365.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VPVX@28216|Betaproteobacteria,3T3CX@506|Alcaligenaceae	28216|Betaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase
MMD2_k127_1973602_1	3988.XP_002536891.1	1.616e-119	392.0	COG0329@1|root,2QQ8M@2759|Eukaryota	2759|Eukaryota	EM	4-hydroxy-tetrahydrodipicolinate synthase	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS,Saccharop_dh_N
MMD2_k127_1973602_5	1502851.FG93_00844	1.923e-31	128.0	COG3232@1|root,COG3232@2|Bacteria,1RB8A@1224|Proteobacteria,2U5N5@28211|Alphaproteobacteria,3JYAP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	5-carboxymethyl-2-hydroxymuconate isomerase	hpcD	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	CHMI
MMD2_k127_1973602_0	319795.Dgeo_2416	3.12e-229	724.0	COG1012@1|root,COG1012@2|Bacteria,1WJ63@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.60	ko:K00151	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04418	RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMD2_k127_1973602_4	398578.Daci_0104	8.996e-35	135.0	2DPNC@1|root,32UMG@2|Bacteria,1N0XW@1224|Proteobacteria,2W38B@28216|Betaproteobacteria,4AI49@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Extradiol ring-cleavage dioxygenase LigAB LigA subunit	-	-	-	-	-	-	-	-	-	-	-	-	LigA
MMD2_k127_1973602_2	398578.Daci_0103	2.351e-119	416.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VTUV@28216|Betaproteobacteria,4AET5@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B	-	-	1.13.11.16,1.13.11.8	ko:K04101,ko:K05713	ko00360,ko00362,ko00624,ko00627,ko01120,ko01220,map00360,map00362,map00624,map00627,map01120,map01220	M00545	R01632,R03550,R04280,R04376,R06788,R09565	RC00233,RC00387,RC00535,RC01140,RC01364,RC02567,RC02694	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
MMD2_k127_2002249_4	622637.KE124770_gene148	6.259e-93	308.0	COG1389@1|root,COG1389@2|Bacteria,1R6T0@1224|Proteobacteria	1224|Proteobacteria	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
MMD2_k127_2002249_2	622637.KE124770_gene147	1.911e-196	617.0	COG1697@1|root,COG1697@2|Bacteria,1NBFJ@1224|Proteobacteria	1224|Proteobacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
MMD2_k127_2002249_7	28444.JODQ01000019_gene7031	1.724e-20	94.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMD2_k127_2002249_6	95619.PM1_0212355	2.011e-40	156.0	COG0454@1|root,COG0457@1|root,COG0456@2|Bacteria,COG0457@2|Bacteria,1N00B@1224|Proteobacteria,1SBF7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMD2_k127_2002249_0	1121423.JONT01000029_gene2389	9.253e-230	724.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,2607A@186807|Peptococcaceae	186801|Clostridia	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
MMD2_k127_2002249_1	483219.LILAB_23465	7.777e-198	640.0	COG2133@1|root,COG2133@2|Bacteria,1PER7@1224|Proteobacteria,4399G@68525|delta/epsilon subdivisions,2X4GV@28221|Deltaproteobacteria,2YYZS@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
MMD2_k127_2002249_3	472759.Nhal_2573	5.229e-148	486.0	COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WZYU@135613|Chromatiales	135613|Chromatiales	S	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16
MMD2_k127_2002249_8	439235.Dalk_4366	1.112e-05	54.0	COG0457@1|root,COG3087@1|root,COG0457@2|Bacteria,COG3087@2|Bacteria,1N5M0@1224|Proteobacteria,42U23@68525|delta/epsilon subdivisions,2WQ2H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_8
MMD2_k127_2002249_5	1234364.AMSF01000015_gene3114	1.53e-91	314.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1X5HG@135614|Xanthomonadales	135614|Xanthomonadales	H	molybdopterin biosynthesis	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
MMD2_k127_2003098_14	1283300.ATXB01000001_gene1865	8.187e-50	181.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1XF3V@135618|Methylococcales	135618|Methylococcales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
MMD2_k127_2003098_16	1163408.UU9_16176	1.3e-31	133.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1X6H0@135614|Xanthomonadales	135614|Xanthomonadales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
MMD2_k127_2003098_10	1158760.AQXP01000036_gene2386	5.706e-62	219.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMD2_k127_2003098_5	498211.CJA_0452	6.153e-82	288.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1FGH0@10|Cellvibrio	1236|Gammaproteobacteria	L	DNA polymerase III, delta subunit	holA	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
MMD2_k127_2003098_18	1045855.DSC_12360	6.325e-18	85.0	COG2835@1|root,COG2835@2|Bacteria,1P6IM@1224|Proteobacteria,1SV7D@1236|Gammaproteobacteria,1X7IE@135614|Xanthomonadales	135614|Xanthomonadales	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
MMD2_k127_2003098_17	546274.EIKCOROL_02381	6.509e-25	108.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,2KS03@206351|Neisseriales	206351|Neisseriales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
MMD2_k127_2003098_2	1122604.JONR01000020_gene514	2.042e-193	614.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1X2ZK@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
MMD2_k127_2003098_9	344747.PM8797T_09624	3.14e-71	248.0	COG0139@1|root,COG0139@2|Bacteria,2J07K@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
MMD2_k127_2003098_1	1297863.APJF01000013_gene3959	4.533e-234	742.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
MMD2_k127_2003098_15	1276756.AUEX01000040_gene346	6.152e-49	183.0	COG2346@1|root,COG2346@2|Bacteria,1PTR2@1224|Proteobacteria,2VVD1@28216|Betaproteobacteria,4AI2B@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
MMD2_k127_2003098_11	1500257.JQNM01000016_gene3105	6.264e-59	220.0	COG0580@1|root,COG0580@2|Bacteria,1PPTN@1224|Proteobacteria,2TW8M@28211|Alphaproteobacteria,4B92I@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	aqpZ	-	-	-	-	-	-	-	-	-	-	-	MIP
MMD2_k127_2003098_8	1408418.JNJH01000106_gene2663	2.575e-73	250.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2TU1U@28211|Alphaproteobacteria,2JS9P@204441|Rhodospirillales	204441|Rhodospirillales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	1.20.4.1	ko:K03741,ko:K03892	-	-	-	-	ko00000,ko01000,ko03000	-	-	-	HTH_20,LMWPc
MMD2_k127_2003098_13	1123399.AQVE01000007_gene1097	9.334e-52	188.0	2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,462HH@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2003098_19	1033802.SSPSH_000243	2.307e-17	91.0	COG2980@1|root,COG2980@2|Bacteria,1PC90@1224|Proteobacteria,1S9NZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
MMD2_k127_2003098_7	1298863.AUEP01000004_gene2264	1.856e-74	269.0	COG1832@1|root,COG1832@2|Bacteria,2HNAY@201174|Actinobacteria,4DVHA@85009|Propionibacteriales	201174|Actinobacteria	S	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2
MMD2_k127_2003098_0	1121946.AUAX01000028_gene5814	3.698e-239	765.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4DMJF@85008|Micromonosporales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
MMD2_k127_2003098_4	1240350.AMZE01000012_gene3608	2.047e-98	336.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1YV6F@136845|Pseudomonas putida group	1236|Gammaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metX	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMD2_k127_2003098_6	1121939.L861_01745	6.259e-79	268.0	COG1765@1|root,COG1765@2|Bacteria,1QUE7@1224|Proteobacteria,1S84Z@1236|Gammaproteobacteria,1XKED@135619|Oceanospirillales	135619|Oceanospirillales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMD2_k127_2003098_3	298655.KI912266_gene4283	1.81e-187	595.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4EV42@85013|Frankiales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
MMD2_k127_2003098_12	3067.XP_002948892.1	2.225e-57	201.0	COG0495@1|root,KOG0435@2759|Eukaryota,37NXR@33090|Viridiplantae,34GSR@3041|Chlorophyta	3041|Chlorophyta	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
MMD2_k127_2040128_4	765911.Thivi_2239	2.405e-92	311.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1WW9Z@135613|Chromatiales	135613|Chromatiales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
MMD2_k127_2040128_12	314278.NB231_05776	4.222e-35	138.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1WYWY@135613|Chromatiales	135613|Chromatiales	J	Sigma 54 modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
MMD2_k127_2040128_2	870187.Thini_1210	6.359e-122	407.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,46003@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
MMD2_k127_2040128_3	207954.MED92_01589	2.386e-102	345.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1XI7T@135619|Oceanospirillales	135619|Oceanospirillales	S	ABC transporter ATP-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
MMD2_k127_2040128_18	1123368.AUIS01000022_gene1051	0.0004705	50.0	COG1934@1|root,COG1934@2|Bacteria,1QCR4@1224|Proteobacteria,1T8HA@1236|Gammaproteobacteria,2NCWA@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
MMD2_k127_2040128_17	1001585.MDS_0961	2.77e-07	63.0	COG3117@1|root,COG3117@2|Bacteria,1PRBD@1224|Proteobacteria,1RW72@1236|Gammaproteobacteria,1YI2R@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
MMD2_k127_2040128_14	1385515.N791_13675	1.158e-22	99.0	COG5007@1|root,COG5007@2|Bacteria,1R3MK@1224|Proteobacteria,1SE4M@1236|Gammaproteobacteria,1X7EE@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the BolA IbaG family	SN15_13775	-	-	-	-	-	-	-	-	-	-	-	BolA
MMD2_k127_2040128_0	765910.MARPU_01745	6.946e-191	603.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1WXB6@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
MMD2_k127_2040128_6	314278.NB231_05696	9.523e-85	293.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	degS	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
MMD2_k127_2040128_9	396588.Tgr7_0749	3.052e-72	248.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1WWVC@135613|Chromatiales	135613|Chromatiales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
MMD2_k127_2040128_1	697282.Mettu_0174	3.545e-186	589.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1XECN@135618|Methylococcales	135618|Methylococcales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
MMD2_k127_2040128_11	1049564.TevJSym_ag00070	6.751e-71	252.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,1J7JW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
MMD2_k127_2040128_8	870187.Thini_1049	1.209e-77	265.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,460HZ@72273|Thiotrichales	72273|Thiotrichales	O	Stringent starvation protein A	-	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_N_3
MMD2_k127_2040128_13	349521.HCH_10003	4.286e-35	144.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1XKFH@135619|Oceanospirillales	135619|Oceanospirillales	S	Stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
MMD2_k127_2040128_7	1452718.JBOY01000066_gene2385	2.648e-78	266.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271,ko:K12961	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005,ko03036	-	-	-	SIS_2
MMD2_k127_2040128_15	472759.Nhal_0474	1.093e-21	98.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1WZJZ@135613|Chromatiales	135613|Chromatiales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
MMD2_k127_2040128_10	314278.NB231_05651	5.68e-71	263.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1WX80@135613|Chromatiales	135613|Chromatiales	M	PFAM LppC	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
MMD2_k127_2040128_5	935863.AWZR01000009_gene45	3.503e-88	302.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1X4QV@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
MMD2_k127_2040128_16	1111728.ATYS01000013_gene4926	4.646e-12	68.0	2E9J1@1|root,333RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2062829_1	497321.C664_10398	1.844e-252	790.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJ5E@28216|Betaproteobacteria,2KVS8@206389|Rhodocyclales	206389|Rhodocyclales	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMD2_k127_2062829_5	1151119.KB895489_gene649	7.558e-136	441.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria	201174|Actinobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMD2_k127_2062829_4	1957.JODX01000030_gene6042	4.213e-150	488.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMD2_k127_2062829_7	1088721.NSU_0072	3.964e-109	370.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,2K0EK@204457|Sphingomonadales	28211|Alphaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMD2_k127_2062829_24	1288494.EBAPG3_2180	2.822e-13	82.0	COG0236@1|root,COG0236@2|Bacteria,1NHIC@1224|Proteobacteria,2VWCN@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
MMD2_k127_2062829_13	693986.MOC_4620	7.444e-66	236.0	COG0412@1|root,COG0412@2|Bacteria,1R6AF@1224|Proteobacteria,2U0YG@28211|Alphaproteobacteria,1JUW3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMD2_k127_2062829_12	1123393.KB891326_gene72	2.11e-72	256.0	COG2187@1|root,COG2187@2|Bacteria,1R98V@1224|Proteobacteria,2VM22@28216|Betaproteobacteria,1KSS9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2062829_6	243233.MCA0563	2.581e-129	422.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1XEG6@135618|Methylococcales	135618|Methylococcales	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
MMD2_k127_2062829_9	243090.RB5429	2.002e-87	308.0	COG4287@1|root,COG4287@2|Bacteria,2IYKE@203682|Planctomycetes	203682|Planctomycetes	S	PhoPQ-activated pathogenicity-related protein	-	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
MMD2_k127_2062829_22	287.DR97_1504	2.163e-19	100.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1YF68@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Universal stress protein family	ydaA	-	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
MMD2_k127_2062829_2	1089552.KI911559_gene1738	1.373e-194	646.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2U2BT@28211|Alphaproteobacteria,2JRCV@204441|Rhodospirillales	204441|Rhodospirillales	Q	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
MMD2_k127_2062829_20	1240350.AMZE01000014_gene4149	1.07e-31	145.0	COG0454@1|root,COG0454@2|Bacteria,1QWI2@1224|Proteobacteria,1T2VH@1236|Gammaproteobacteria,1YY91@136845|Pseudomonas putida group	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMD2_k127_2062829_21	1238182.C882_0029	1.981e-21	104.0	COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,2UCCK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_2062829_15	323850.Shew_3240	7.006e-63	223.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	nodW	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMD2_k127_2062829_11	983545.Glaag_2166	2.099e-79	295.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,465JT@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	fixL	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd,Response_reg
MMD2_k127_2062829_17	1452718.JBOY01000002_gene468	3.103e-50	191.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	universal stress protein	ydaA	-	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
MMD2_k127_2062829_3	1122194.AUHU01000013_gene731	7.3e-189	600.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,469FI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	sqr	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMD2_k127_2062829_14	1122604.JONR01000009_gene2465	1.854e-65	241.0	COG1538@1|root,COG1538@2|Bacteria,1N23P@1224|Proteobacteria,1RMXN@1236|Gammaproteobacteria,1X8EQ@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD2_k127_2062829_8	765914.ThisiDRAFT_0633	4.065e-94	321.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1WX31@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMD2_k127_2062829_0	396588.Tgr7_1129	0.0	1323.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWJ6@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMD2_k127_2062829_19	1114964.L485_09235	8.296e-37	146.0	arCOG05203@1|root,31A0K@2|Bacteria,1RHZR@1224|Proteobacteria,2U9JR@28211|Alphaproteobacteria,2KB6H@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2062829_10	864702.OsccyDRAFT_4705	4.225e-85	297.0	COG3174@1|root,COG3174@2|Bacteria,1G4HU@1117|Cyanobacteria	1117|Cyanobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
MMD2_k127_2062829_18	1231185.BAMP01000062_gene167	5.351e-46	186.0	COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,2U9F0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	DsrE/DsrF-like family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
MMD2_k127_2062829_16	1317124.DW2_00405	5.374e-59	216.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2U3PI@28211|Alphaproteobacteria,2XPCM@285107|Thioclava	28211|Alphaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
MMD2_k127_2062829_23	857087.Metme_0188	1.161e-16	84.0	2DPP8@1|root,332V3@2|Bacteria,1NJM6@1224|Proteobacteria,1SIP1@1236|Gammaproteobacteria,1XFGW@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF3240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3240
MMD2_k127_2171087_10	479432.Sros_0431	1.908e-37	145.0	COG0596@1|root,COG0596@2|Bacteria,2I32Y@201174|Actinobacteria,4ER3J@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMD2_k127_2171087_6	404589.Anae109_0580	1.148e-69	250.0	COG3795@1|root,COG3795@2|Bacteria,1Q42B@1224|Proteobacteria,439VS@68525|delta/epsilon subdivisions,2X59V@28221|Deltaproteobacteria,2Z0B4@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMD2_k127_2171087_1	1157708.KB907453_gene4073	7.981e-179	569.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2VKYD@28216|Betaproteobacteria,4AAJ6@80864|Comamonadaceae	28216|Betaproteobacteria	K	RNA polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_2171087_7	1380394.JADL01000010_gene4296	9.819e-49	187.0	COG3386@1|root,COG3386@2|Bacteria,1RHPS@1224|Proteobacteria,2UBD9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2171087_14	627192.SLG_36720	0.0008692	46.0	COG4319@1|root,COG4319@2|Bacteria,1QUR3@1224|Proteobacteria,2TW48@28211|Alphaproteobacteria,2K85Y@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_2171087_8	247633.GP2143_17796	7.314e-44	181.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2171087_5	247633.GP2143_17791	2.54e-73	276.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2171087_9	247633.GP2143_18131	6.317e-38	146.0	2C42J@1|root,3359Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2171087_2	365046.Rta_17940	3.567e-177	566.0	COG1249@1|root,COG1249@2|Bacteria,1QW6X@1224|Proteobacteria,2WHCB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
MMD2_k127_2171087_0	1279009.ADICEAN_01147	0.0	1064.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,47K8A@768503|Cytophagia	976|Bacteroidetes	C	Monomeric isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
MMD2_k127_2171087_4	1123504.JQKD01000003_gene667	3.69e-123	402.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria	1224|Proteobacteria	G	fructose-bisphosphate aldolase	fda	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
MMD2_k127_2171087_11	479431.Namu_1448	2.146e-23	104.0	COG1396@1|root,COG1396@2|Bacteria,2GPQW@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMD2_k127_2171087_3	469371.Tbis_2867	9.118e-177	586.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E06H@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMD2_k127_2177061_24	234267.Acid_6434	3.459e-98	329.0	COG1721@1|root,COG1721@2|Bacteria,3Y5XW@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMD2_k127_2177061_13	1267534.KB906756_gene97	4.456e-136	442.0	COG0714@1|root,COG0714@2|Bacteria,3Y3BH@57723|Acidobacteria,2JP47@204432|Acidobacteriia	204432|Acidobacteriia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
MMD2_k127_2177061_10	1267535.KB906767_gene907	9.675e-144	496.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,TPR_16,TPR_19,TPR_8
MMD2_k127_2177061_41	234267.Acid_6437	4.436e-46	183.0	COG4249@1|root,COG4249@2|Bacteria,3Y6DQ@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
MMD2_k127_2177061_9	1267535.KB906767_gene905	6.15e-166	547.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,3Y6YC@57723|Acidobacteria	57723|Acidobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
MMD2_k127_2177061_30	1340493.JNIF01000003_gene4787	3.339e-86	293.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
MMD2_k127_2177061_14	1442599.JAAN01000005_gene1025	8.66e-134	454.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,1RZ17@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMD2_k127_2177061_52	1122134.KB893650_gene1679	5.606e-17	94.0	COG3658@1|root,COG3658@2|Bacteria,1N6Y9@1224|Proteobacteria,1SCBR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PgaD-like protein	-	-	-	ko:K11937	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	PgaD
MMD2_k127_2177061_8	1122134.KB893650_gene1680	1.377e-171	569.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,1RMS4@1236|Gammaproteobacteria,1XIIB@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyl transferase family 21	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3
MMD2_k127_2177061_7	338963.Pcar_2791	3.261e-173	568.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,42PMY@68525|delta/epsilon subdivisions,2WPU5@28221|Deltaproteobacteria,43SS0@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1
MMD2_k127_2177061_25	666681.M301_0049	3.154e-95	342.0	COG0457@1|root,COG0457@2|Bacteria,1RA3P@1224|Proteobacteria,2VRWC@28216|Betaproteobacteria,2KNR7@206350|Nitrosomonadales	28216|Betaproteobacteria	S	Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA	pgaA	-	-	ko:K11935	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	TPR_15,TPR_16,TPR_19
MMD2_k127_2177061_40	402626.Rpic_0855	1.27e-56	214.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2VN9Y@28216|Betaproteobacteria,1K6AS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
MMD2_k127_2177061_49	627192.SLG_25060	7.137e-32	132.0	COG1309@1|root,COG1309@2|Bacteria,1RIG0@1224|Proteobacteria,2VFM1@28211|Alphaproteobacteria,2KA9F@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMD2_k127_2177061_16	627192.SLG_26390	9.539e-116	411.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1QU0Y@1224|Proteobacteria,2TW5W@28211|Alphaproteobacteria,2KEBP@204457|Sphingomonadales	204457|Sphingomonadales	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_2177061_29	314285.KT71_05632	8.303e-90	304.0	COG1917@1|root,COG1917@2|Bacteria,1QU6U@1224|Proteobacteria,1T1P4@1236|Gammaproteobacteria,1J7FW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
MMD2_k127_2177061_35	999141.GME_09219	2.333e-73	252.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,1S2I8@1236|Gammaproteobacteria,1XJ5Z@135619|Oceanospirillales	135619|Oceanospirillales	O	Maleylacetoacetate isomerase	-	-	5.2.1.4	ko:K01801	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	GST_C_2,GST_C_3,GST_N,GST_N_3
MMD2_k127_2177061_36	83406.HDN1F_20850	6.43e-69	240.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1J5ZZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.7.13,2.7.7.99	ko:K00966,ko:K00992	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMD2_k127_2177061_11	105559.Nwat_1394	1.915e-143	481.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales	135613|Chromatiales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
MMD2_k127_2177061_23	765912.Thimo_3266	3.548e-99	339.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1WVWN@135613|Chromatiales	135613|Chromatiales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N
MMD2_k127_2177061_20	1122604.JONR01000006_gene2540	1.889e-106	357.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1X2ZP@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
MMD2_k127_2177061_33	421052.F945_00555	8.463e-79	285.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,3NK8E@468|Moraxellaceae	1236|Gammaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
MMD2_k127_2177061_44	247633.GP2143_17801	4.216e-42	159.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2177061_34	247633.GP2143_17791	4.334e-78	270.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2177061_28	1007104.SUS17_2461	1.751e-90	317.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales	204457|Sphingomonadales	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
MMD2_k127_2177061_39	247633.GP2143_18126	1.277e-63	230.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2177061_43	247633.GP2143_17796	3.03e-44	177.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2177061_38	765914.ThisiDRAFT_2710	3.357e-64	224.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1WXKW@135613|Chromatiales	135613|Chromatiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMD2_k127_2177061_3	396588.Tgr7_1907	6.789e-230	727.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
MMD2_k127_2177061_5	1384054.N790_03185	3.651e-186	593.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,1RRMM@1236|Gammaproteobacteria,1X2YX@135614|Xanthomonadales	135614|Xanthomonadales	E	phospho-2-dehydro-3-deoxyheptonate aldolase	dhs1	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
MMD2_k127_2177061_59	1385515.N791_02970	4.194e-05	54.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1X3VR@135614|Xanthomonadales	135614|Xanthomonadales	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
MMD2_k127_2177061_1	349124.Hhal_1388	2.517e-311	1002.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1WWGW@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM ATP-dependent helicase HrpA	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
MMD2_k127_2177061_32	1049564.TevJSym_be00360	2.136e-83	295.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,1J5VV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction histidine kinase	phoQ	-	2.7.13.3	ko:K07637	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,PhoQ_Sensor
MMD2_k127_2177061_26	1500890.JQNL01000001_gene2661	5.553e-95	316.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1X2XT@135614|Xanthomonadales	135614|Xanthomonadales	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07660	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_2177061_50	187272.Mlg_2507	6.323e-30	126.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,1X1Q9@135613|Chromatiales	135613|Chromatiales	S	17 kDa surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
MMD2_k127_2177061_31	69395.JQLZ01000005_gene3874	8.234e-85	288.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2KFIN@204458|Caulobacterales	204458|Caulobacterales	S	TIGRFAM MazG family protein	-	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
MMD2_k127_2177061_48	1122603.ATVI01000007_gene1650	1.418e-36	156.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,1X3T9@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA mismatch repair protein MutT	-	-	-	-	-	-	-	-	-	-	-	-	DUF1289,NUDIX
MMD2_k127_2177061_4	1122604.JONR01000001_gene1738	9.49e-208	655.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales	135614|Xanthomonadales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
MMD2_k127_2177061_6	1123073.KB899242_gene1426	8.997e-176	562.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1X3E0@135614|Xanthomonadales	135614|Xanthomonadales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
MMD2_k127_2177061_51	1001585.MDS_2364	9.321e-20	95.0	COG2153@1|root,COG2153@2|Bacteria,1N7TN@1224|Proteobacteria,1SCI6@1236|Gammaproteobacteria,1YFZC@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	protein acetylation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2177061_42	713586.KB900536_gene654	1.932e-44	166.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,1S970@1236|Gammaproteobacteria,1X18A@135613|Chromatiales	135613|Chromatiales	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMD2_k127_2177061_15	1279017.AQYJ01000029_gene3825	3.963e-121	405.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,464B7@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
MMD2_k127_2177061_0	1211114.ALIP01000115_gene1477	0.0	1185.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1X3SP@135614|Xanthomonadales	135614|Xanthomonadales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMD2_k127_2177061_19	717774.Marme_3084	3.603e-111	369.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,1XH81@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
MMD2_k127_2177061_27	1123377.AUIV01000002_gene1193	1.114e-91	304.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,1S3QT@1236|Gammaproteobacteria,1X68E@135614|Xanthomonadales	135614|Xanthomonadales	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
MMD2_k127_2177061_37	1123242.JH636436_gene594	1.37e-68	239.0	COG1611@1|root,COG1611@2|Bacteria,2IZK9@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMD2_k127_2177061_45	1380391.JIAS01000015_gene114	5.477e-42	166.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1MWTF@1224|Proteobacteria,2TTWC@28211|Alphaproteobacteria,2JU61@204441|Rhodospirillales	204441|Rhodospirillales	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652,ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
MMD2_k127_2177061_17	450851.PHZ_c2571	6.88e-115	390.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,2KFNJ@204458|Caulobacterales	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMD2_k127_2177061_47	414684.RC1_2329	1.085e-37	162.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,2JRW7@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_2,GST_N_3
MMD2_k127_2177061_55	1318628.MARLIPOL_06034	4.595e-08	65.0	COG1040@1|root,COG1040@2|Bacteria,1REX9@1224|Proteobacteria,1S568@1236|Gammaproteobacteria,4671D@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2177061_46	517417.Cpar_0675	1.682e-39	156.0	COG1451@1|root,COG1451@2|Bacteria,1FE2Z@1090|Chlorobi	1090|Chlorobi	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
MMD2_k127_2177061_57	379066.GAU_2337	5.196e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1ZUV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2177061_22	1300345.LF41_1397	8.408e-101	335.0	COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria,1X3N8@135614|Xanthomonadales	135614|Xanthomonadales	L	Preprotein translocase subunit TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
MMD2_k127_2177061_56	1112217.PPL19_06896	1.349e-06	57.0	COG0551@1|root,COG0551@2|Bacteria,1PZFI@1224|Proteobacteria,1RQ64@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0551 Zn-finger domain associated with topoisomerase type I	-	-	-	-	-	-	-	-	-	-	-	-	NERD,zf-C4_Topoisom
MMD2_k127_2177061_12	1121015.N789_00780	1.392e-140	458.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1X541@135614|Xanthomonadales	135614|Xanthomonadales	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
MMD2_k127_2177061_2	309807.SRU_0691	2.329e-262	831.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1FIND@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	homoserine dehydrogenase	-	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3
MMD2_k127_2177061_21	1121013.P873_03670	6.817e-105	345.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1X3J3@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
MMD2_k127_2177061_18	926550.CLDAP_36930	1.559e-112	377.0	COG0477@1|root,COG0477@2|Bacteria,2GA8P@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMD2_k127_219478_8	400682.PAC_15705797	4.178e-17	80.0	COG0050@1|root,KOG0460@2759|Eukaryota,38BHM@33154|Opisthokonta,3BE5J@33208|Metazoa	33208|Metazoa	J	translation elongation factor activity	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMD2_k127_219478_9	1408445.JHXP01000047_gene1751	9.229e-06	49.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1JECV@118969|Legionellales	118969|Legionellales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
MMD2_k127_219478_7	765913.ThidrDRAFT_1724	3.061e-28	117.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1X2GF@135613|Chromatiales	135613|Chromatiales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
MMD2_k127_219478_3	396588.Tgr7_2336	2.826e-90	300.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1WWG3@135613|Chromatiales	135613|Chromatiales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
MMD2_k127_219478_4	1158760.AQXP01000016_gene1866	9.025e-69	235.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,1WXZD@135613|Chromatiales	135613|Chromatiales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
MMD2_k127_219478_2	519989.ECTPHS_13238	1.746e-97	323.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1WW17@135613|Chromatiales	135613|Chromatiales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
MMD2_k127_219478_5	1286106.MPL1_05317	2.805e-48	178.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,460IU@72273|Thiotrichales	72273|Thiotrichales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
MMD2_k127_219478_6	400682.PAC_15704540	1.729e-39	150.0	COG0222@1|root,KOG1715@2759|Eukaryota,3A6HQ@33154|Opisthokonta,3BTPK@33208|Metazoa	33208|Metazoa	J	Ribosomal protein L7/L12 dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L12,Ribosomal_L12_N
MMD2_k127_219478_0	713586.KB900536_gene1177	0.0	2163.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
MMD2_k127_219478_1	765914.ThisiDRAFT_0951	0.0	1585.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMD2_k127_2249978_0	234267.Acid_6432	8.051e-165	565.0	COG0497@1|root,COG3266@1|root,COG0497@2|Bacteria,COG3266@2|Bacteria,3Y6KC@57723|Acidobacteria	57723|Acidobacteria	L	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2249978_1	1267534.KB906756_gene95	7.166e-87	312.0	COG1240@1|root,COG1240@2|Bacteria,3Y655@57723|Acidobacteria	57723|Acidobacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
MMD2_k127_235888_30	663610.JQKO01000012_gene3076	2.497e-88	306.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_235888_13	551789.ATVJ01000001_gene1519	4.056e-151	494.0	COG1073@1|root,COG1073@2|Bacteria,1QTY2@1224|Proteobacteria,2TX8W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tannase and feruloyl esterase	-	-	3.1.1.102	ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	Tannase
MMD2_k127_235888_32	234267.Acid_1170	6.544e-77	267.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	2|Bacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
MMD2_k127_235888_34	351607.Acel_1040	1.386e-74	259.0	COG1028@1|root,COG1028@2|Bacteria,2I6UQ@201174|Actinobacteria,4EVQ5@85013|Frankiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
MMD2_k127_235888_35	1463917.JODC01000007_gene7463	2.421e-70	252.0	COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD2_k127_235888_40	1134912.AJTV01000002_gene1748	3.45e-51	197.0	2AC8B@1|root,311T0@2|Bacteria,1NK0P@1224|Proteobacteria,2VD5M@28211|Alphaproteobacteria,3713U@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_235888_22	378806.STAUR_6905	6.941e-110	358.0	COG0625@1|root,COG0625@2|Bacteria,1PENB@1224|Proteobacteria,43828@68525|delta/epsilon subdivisions,2X3CE@28221|Deltaproteobacteria,2YVE3@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
MMD2_k127_235888_25	395965.Msil_1617	2.823e-104	359.0	COG0596@1|root,COG0596@2|Bacteria,1QXD5@1224|Proteobacteria,2UNNR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_235888_4	1380394.JADL01000002_gene1394	1.153e-199	631.0	COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria,2JT4J@204441|Rhodospirillales	204441|Rhodospirillales	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
MMD2_k127_235888_8	469371.Tbis_2867	2.163e-172	580.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E06H@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMD2_k127_235888_43	365044.Pnap_0570	8.262e-32	139.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2VK61@28216|Betaproteobacteria,4ABNM@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM SMP-30 Gluconolaconase LRE domain protein	gnl1	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
MMD2_k127_235888_53	1122963.AUHB01000005_gene2930	1.815e-18	93.0	COG0346@1|root,COG0346@2|Bacteria,1PJ3N@1224|Proteobacteria,2UF0Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_235888_47	627192.SLG_36710	1.148e-25	122.0	COG4319@1|root,COG4319@2|Bacteria,1QUR3@1224|Proteobacteria,2TW48@28211|Alphaproteobacteria,2K85Y@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_235888_48	675635.Psed_2486	3.757e-25	113.0	COG3871@1|root,COG3871@2|Bacteria,2HDER@201174|Actinobacteria	201174|Actinobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_235888_44	1298867.AUES01000006_gene279	4.194e-30	134.0	COG2128@1|root,COG2128@2|Bacteria,1MVWP@1224|Proteobacteria,2VGCN@28211|Alphaproteobacteria,3K3SE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMD2_k127_235888_51	1429916.X566_16385	2.356e-21	107.0	COG2128@1|root,COG2128@2|Bacteria,1MVWP@1224|Proteobacteria,2VGCN@28211|Alphaproteobacteria,3K3SE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMD2_k127_235888_54	404589.Anae109_2978	1.487e-10	70.0	2DSZ0@1|root,33HZS@2|Bacteria,1NHUW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_235888_9	247633.GP2143_17871	1.527e-166	539.0	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,1RR5H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0793 Periplasmic protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
MMD2_k127_235888_11	1110502.TMO_0244	3.828e-161	526.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2JQGA@204441|Rhodospirillales	204441|Rhodospirillales	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
MMD2_k127_235888_42	1110502.TMO_0243	9.41e-34	136.0	COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,2TU4N@28211|Alphaproteobacteria,2JRAM@204441|Rhodospirillales	204441|Rhodospirillales	G	TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
MMD2_k127_235888_24	1110502.TMO_0242	1.112e-105	353.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TS46@28211|Alphaproteobacteria,2JQRM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	dctP	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
MMD2_k127_235888_14	1172188.KB911828_gene4082	1.622e-147	475.0	COG1071@1|root,COG1071@2|Bacteria,2HFTI@201174|Actinobacteria,4FIZS@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
MMD2_k127_235888_12	675812.VHA_002641	2.17e-154	492.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,1XZWA@135623|Vibrionales	135623|Vibrionales	C	Transketolase, pyrimidine binding domain	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMD2_k127_235888_19	1313172.YM304_29650	6.224e-120	401.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4CMW0@84992|Acidimicrobiia	84992|Acidimicrobiia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMD2_k127_235888_20	1380394.JADL01000002_gene1393	1.083e-114	384.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2U2X9@28211|Alphaproteobacteria,2JTJW@204441|Rhodospirillales	204441|Rhodospirillales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
MMD2_k127_235888_55	1283300.ATXB01000001_gene1279	5.776e-09	64.0	2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SHAU@1236|Gammaproteobacteria,1XFBV@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_235888_1	292415.Tbd_0058	2.856e-220	699.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,1KSBS@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
MMD2_k127_235888_0	631454.N177_1753	1.131e-257	803.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,1JNGM@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	-	-	-	-	-	-	-	-	-	Cpn60_TCP1
MMD2_k127_235888_15	396588.Tgr7_2073	3.531e-138	453.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
MMD2_k127_235888_23	1267535.KB906767_gene4866	1.942e-107	360.0	COG2863@1|root,COG2863@2|Bacteria	2|Bacteria	C	cytochrome	-	-	-	ko:K17230	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001	-	-	-	Cytochrom_C,Cytochrome_CBB3,DUF1566
MMD2_k127_235888_16	1123060.JONP01000012_gene2827	5.455e-130	424.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMD2_k127_235888_18	247633.GP2143_01745	3.578e-120	406.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1J4KZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
MMD2_k127_235888_52	627192.SLG_25160	4.594e-21	106.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_235888_27	523791.Kkor_2302	4.517e-98	346.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin-like,DUF3494,TIG
MMD2_k127_235888_41	795797.C497_13081	2.912e-44	174.0	COG3243@1|root,arCOG06234@1|root,arCOG06234@2157|Archaea,arCOG06344@2157|Archaea,2XSZS@28890|Euryarchaeota,23SX8@183963|Halobacteria	183963|Halobacteria	I	poly(R)-hydroxyalkanoic acid synthase subunit PhaC	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,HHH_5
MMD2_k127_235888_26	1297570.MESS4_830366	3.898e-103	340.0	COG1028@1|root,COG1028@2|Bacteria,1MU3W@1224|Proteobacteria,2TT5X@28211|Alphaproteobacteria,43IC2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Short chain dehydrogenase	linC	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMD2_k127_235888_31	1123256.KB907944_gene405	3.3e-87	301.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,1RPR3@1236|Gammaproteobacteria,1X5E0@135614|Xanthomonadales	135614|Xanthomonadales	FL	Methyltransferase	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
MMD2_k127_235888_10	666685.R2APBS1_2334	6.934e-164	522.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1X493@135614|Xanthomonadales	135614|Xanthomonadales	P	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
MMD2_k127_235888_60	105559.Nwat_0789	5.825e-05	53.0	2DR6H@1|root,33ADR@2|Bacteria,1NHEA@1224|Proteobacteria,1SW2J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_235888_5	234267.Acid_6269	4.805e-188	615.0	COG0577@1|root,COG0577@2|Bacteria,3Y6MX@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_235888_58	388739.RSK20926_02272	1.175e-06	55.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
MMD2_k127_235888_46	305700.B447_20503	1.502e-27	114.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
MMD2_k127_235888_57	1100720.ALKN01000028_gene2468	1.116e-07	53.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,2VTY4@28216|Betaproteobacteria,4AFP7@80864|Comamonadaceae	28216|Betaproteobacteria	K	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
MMD2_k127_235888_50	83406.HDN1F_31300	8.388e-23	105.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,1J81D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
MMD2_k127_235888_28	392499.Swit_0807	2.007e-94	321.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,2K0SR@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
MMD2_k127_235888_33	391625.PPSIR1_41814	7.927e-77	274.0	COG1109@1|root,COG1482@1|root,COG1109@2|Bacteria,COG1482@2|Bacteria	2|Bacteria	G	cell wall glycoprotein biosynthetic process	manA	GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.14.13.81,1.6.5.5,2.7.7.13,5.3.1.8,5.4.2.10,5.4.2.2,5.4.2.8	ko:K00344,ko:K01809,ko:K01840,ko:K03431,ko:K04035,ko:K15778,ko:K16881	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko00860,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map00860,map01100,map01110,map01120,map01130	M00114,M00362	R00885,R00959,R01057,R01818,R01819,R02060,R06265,R06266,R06267,R08639,R10068	RC00002,RC00376,RC00408,RC00741,RC01491,RC01492,RC03042	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178,iAPECO1_1312.APECO1_696,iECOK1_1307.ECOK1_1731,iECS88_1305.ECS88_1659,iSFV_1184.SFV_1629,iSF_1195.SF1636,iSFxv_1172.SFxv_1833,iS_1188.S1767,iUMN146_1321.UM146_09090,iUTI89_1310.UTI89_C1801	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PMI_typeI
MMD2_k127_235888_37	1005395.CSV86_09862	6.244e-66	232.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1YWH7@136845|Pseudomonas putida group	1236|Gammaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718	BPL_LplA_LipB
MMD2_k127_235888_56	1123393.KB891330_gene832	4.695e-08	65.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,1KTD2@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF493)	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
MMD2_k127_235888_21	765910.MARPU_16695	5.361e-112	389.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1WWCM@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
MMD2_k127_235888_39	713586.KB900536_gene2644	4.503e-53	200.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1WW9X@135613|Chromatiales	135613|Chromatiales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
MMD2_k127_235888_29	1042377.AFPJ01000030_gene453	1.456e-89	304.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,4659R@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Lytic murein transglycosylase	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
MMD2_k127_235888_17	396588.Tgr7_2710	3.391e-129	426.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
MMD2_k127_235888_7	765910.MARPU_16675	2.885e-176	572.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1WWAT@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMD2_k127_235888_45	1158182.KB905021_gene709	2.211e-28	128.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1WYH2@135613|Chromatiales	135613|Chromatiales	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
MMD2_k127_235888_36	768671.ThimaDRAFT_3990	3.255e-68	243.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1WWKS@135613|Chromatiales	135613|Chromatiales	M	Involved in formation and maintenance of cell shape	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
MMD2_k127_235888_6	243233.MCA0100	1.194e-179	567.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1XESQ@135618|Methylococcales	135618|Methylococcales	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMD2_k127_235888_49	1121374.KB891579_gene1738	2.609e-24	105.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
MMD2_k127_235888_3	83406.HDN1F_06160	4.645e-205	647.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1J4IG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMD2_k127_235888_2	519989.ECTPHS_09268	8.1e-216	679.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
MMD2_k127_235888_38	713586.KB900536_gene1600	4.128e-56	221.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1WWKK@135613|Chromatiales	135613|Chromatiales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
MMD2_k127_2365683_7	1340493.JNIF01000004_gene600	1.165e-62	232.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
MMD2_k127_2365683_11	1267534.KB906758_gene2405	5.233e-49	188.0	COG0491@1|root,COG0491@2|Bacteria,3Y48F@57723|Acidobacteria,2JIRT@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_2365683_2	357808.RoseRS_3704	7.785e-141	482.0	COG0281@1|root,COG0281@2|Bacteria,2G65R@200795|Chloroflexi,376YS@32061|Chloroflexia	32061|Chloroflexia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
MMD2_k127_2365683_20	1088721.NSU_2830	1.83e-17	94.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2365683_18	1236959.BAMT01000015_gene2850	2.947e-27	121.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2365683_3	1500897.JQNA01000002_gene5027	1.227e-130	432.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2W1H3@28216|Betaproteobacteria,1K1F5@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMD2_k127_2365683_14	497964.CfE428DRAFT_1821	3.858e-42	173.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD2_k127_2365683_9	497964.CfE428DRAFT_3322	2.249e-59	222.0	COG0715@1|root,COG0715@2|Bacteria,46U6U@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
MMD2_k127_2365683_17	316055.RPE_3044	2.132e-27	124.0	2919Q@1|root,32TZW@2|Bacteria,1R3DM@1224|Proteobacteria,2U015@28211|Alphaproteobacteria,3K71Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2365683_16	396588.Tgr7_2791	2.813e-33	139.0	COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria,1RN4J@1236|Gammaproteobacteria,1WZ1V@135613|Chromatiales	135613|Chromatiales	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
MMD2_k127_2365683_12	1229172.JQFA01000002_gene3797	1.462e-47	175.0	COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMD2_k127_2365683_8	391735.Veis_1528	1.241e-62	216.0	COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,2VY6Q@28216|Betaproteobacteria,4AFUM@80864|Comamonadaceae	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
MMD2_k127_2365683_22	1123277.KB893194_gene5878	0.0002209	47.0	COG0531@1|root,COG0531@2|Bacteria,4NJPZ@976|Bacteroidetes,47MX2@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMD2_k127_2365683_21	468059.AUHA01000006_gene2985	1.994e-13	72.0	COG0531@1|root,COG0531@2|Bacteria,4NJPZ@976|Bacteroidetes,1IRQU@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMD2_k127_2365683_6	1318628.MARLIPOL_09214	1.757e-89	305.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,465IU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS116/IS110/IS902 family	Z012_08285	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
MMD2_k127_2365683_10	1340493.JNIF01000003_gene3476	5.722e-57	218.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
MMD2_k127_2365683_15	180281.CPCC7001_367	2.303e-37	152.0	COG0491@1|root,COG0491@2|Bacteria,1G400@1117|Cyanobacteria	1117|Cyanobacteria	S	Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_2365683_4	886293.Sinac_1154	6.301e-107	363.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_2365683_0	886293.Sinac_1153	3.25e-167	556.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_2365683_5	1454004.AW11_00593	1.104e-105	351.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,1KQCM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMD2_k127_2365683_19	1123279.ATUS01000001_gene1570	1.512e-18	91.0	2EQ70@1|root,33HT9@2|Bacteria,1NIHT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2365683_1	1038860.AXAP01000018_gene3108	2.728e-163	534.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_2365683_13	157783.LK03_20435	2.882e-43	169.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2393783_0	1267534.KB906757_gene1130	5.437e-136	445.0	COG0671@1|root,COG0671@2|Bacteria,3Y8DY@57723|Acidobacteria	57723|Acidobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
MMD2_k127_2393783_1	1121952.ATXT01000011_gene3025	8.34e-117	411.0	COG2909@1|root,COG3710@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,2GJAR@201174|Actinobacteria,4FMKW@85023|Microbacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
MMD2_k127_2393783_6	470.IX87_12725	3.23e-12	76.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,3NKKZ@468|Moraxellaceae	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
MMD2_k127_2393783_9	876044.IMCC3088_699	4.486e-09	61.0	COG0399@1|root,COG0399@2|Bacteria,1N3NC@1224|Proteobacteria,1SAHP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
MMD2_k127_2393783_5	172088.AUGA01000018_gene2074	1.206e-14	86.0	28PP7@1|root,2ZCBP@2|Bacteria,1R53H@1224|Proteobacteria,2VGU9@28211|Alphaproteobacteria,3JUCR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2393783_7	1101195.Meth11DRAFT_1464	1.765e-11	70.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2393783_3	157783.LK03_20435	3.088e-26	119.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2393783_2	1168034.FH5T_02255	1.928e-49	188.0	COG1506@1|root,COG1506@2|Bacteria,4PN2U@976|Bacteroidetes	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2419662_5	396588.Tgr7_2922	1.036e-31	131.0	2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1WZKG@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4426
MMD2_k127_2419662_6	1265313.HRUBRA_00305	7.794e-23	108.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1J702@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
MMD2_k127_2419662_3	1123368.AUIS01000011_gene1188	1.558e-45	176.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S4MG@1236|Gammaproteobacteria,2NBWE@225057|Acidithiobacillales	225057|Acidithiobacillales	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Peptidase_S15
MMD2_k127_2419662_0	1137799.GZ78_08570	1.242e-225	715.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1XHR3@135619|Oceanospirillales	135619|Oceanospirillales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
MMD2_k127_2419662_2	396588.Tgr7_0189	1.55e-69	245.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
MMD2_k127_2419662_1	1122604.JONR01000035_gene351	1.16e-185	592.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1X3RE@135614|Xanthomonadales	135614|Xanthomonadales	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
MMD2_k127_2419662_4	644076.SCH4B_0425	1.886e-36	141.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2TS2U@28211|Alphaproteobacteria,4NC3T@97050|Ruegeria	28211|Alphaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMD2_k127_2427166_10	1122185.N792_13380	1.368e-17	86.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,1X3QH@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the DnaA family. HdA subfamily	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA,IstB_IS21
MMD2_k127_2427166_4	1123253.AUBD01000016_gene1963	2.172e-69	244.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1X4PZ@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the WrbA family	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
MMD2_k127_2427166_9	396588.Tgr7_2243	1.15e-22	103.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
MMD2_k127_2427166_7	247633.GP2143_10127	8.67e-53	194.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,1J5TG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
MMD2_k127_2427166_5	1128912.GMES_4111	3.639e-69	258.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,4645F@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
MMD2_k127_2427166_3	243233.MCA2276	2.36e-79	280.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1XF2F@135618|Methylococcales	135618|Methylococcales	L	Phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMD2_k127_2427166_8	1500893.JQNB01000001_gene3561	2.575e-48	179.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales	135614|Xanthomonadales	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
MMD2_k127_2427166_0	1397528.Q671_02870	9.9e-229	731.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1XHRK@135619|Oceanospirillales	135619|Oceanospirillales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
MMD2_k127_2427166_1	1122603.ATVI01000005_gene3516	1.709e-127	440.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1X3BD@135614|Xanthomonadales	135614|Xanthomonadales	E	Transglutaminase/protease-like homologues	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
MMD2_k127_2427166_6	1122603.ATVI01000005_gene3517	9.43e-65	233.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,1X33K@135614|Xanthomonadales	135614|Xanthomonadales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMD2_k127_2427166_2	631362.Thi970DRAFT_03646	6.286e-84	284.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,1WXIF@135613|Chromatiales	135613|Chromatiales	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
MMD2_k127_2432285_5	1220583.GOACH_01_01850	2.223e-19	97.0	COG1062@1|root,COG1062@2|Bacteria,2H5QJ@201174|Actinobacteria	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_2432285_0	1380391.JIAS01000013_gene3696	1.682e-72	257.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
MMD2_k127_2432285_1	1349767.GJA_2515	1.771e-55	202.0	COG1309@1|root,COG1309@2|Bacteria,1N4J6@1224|Proteobacteria,2WFDX@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
MMD2_k127_2432285_8	521674.Plim_2781	3.796e-05	55.0	COG4099@1|root,COG4099@2|Bacteria,2IYJQ@203682|Planctomycetes	203682|Planctomycetes	S	allantoin biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
MMD2_k127_2432285_4	551275.KB899546_gene2355	6.696e-20	102.0	COG0251@1|root,COG0251@2|Bacteria,1RH8Y@1224|Proteobacteria,2U9P4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
MMD2_k127_2432285_6	351160.RCIX849	6.514e-15	80.0	COG4430@1|root,arCOG10241@2157|Archaea	351160.RCIX849|-	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2432285_3	740709.A10D4_10441	7.237e-21	107.0	2DBBZ@1|root,2Z8BC@2|Bacteria,1QVUC@1224|Proteobacteria,1T2J3@1236|Gammaproteobacteria,2QFX1@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
MMD2_k127_2432285_2	247633.GP2143_17796	5.923e-38	156.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2432285_7	627192.SLG_26300	7.136e-15	74.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2450673_6	196367.JNFG01000008_gene6597	3.019e-147	480.0	COG1082@1|root,COG1082@2|Bacteria,1NHXC@1224|Proteobacteria,2VRSG@28216|Betaproteobacteria,1K889@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMD2_k127_2450673_14	698761.RTCIAT899_CH14965	2.106e-74	261.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2U255@28211|Alphaproteobacteria,4BGI8@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMD2_k127_2450673_15	1120956.JHZK01000002_gene1025	4.852e-63	240.0	COG0673@1|root,COG0673@2|Bacteria,1PGFP@1224|Proteobacteria,2V8DN@28211|Alphaproteobacteria,1JQA3@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMD2_k127_2450673_11	745014.OMB55_00023870	9.368e-93	313.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_2450673_2	1297742.A176_04241	1.463e-203	663.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_2450673_20	663610.JQKO01000003_gene1499	1.281e-33	135.0	COG1917@1|root,COG1917@2|Bacteria,1QEE2@1224|Proteobacteria,2UDNV@28211|Alphaproteobacteria,3NCT7@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4437
MMD2_k127_2450673_5	395964.KE386496_gene2650	1.305e-155	503.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,3NC4T@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
MMD2_k127_2450673_17	318996.AXAZ01000107_gene3754	3.245e-52	190.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2TWPT@28211|Alphaproteobacteria,3JXB2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_2450673_9	1254432.SCE1572_09415	9.487e-119	394.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2YUZM@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
MMD2_k127_2450673_10	1254432.SCE1572_09420	1.632e-116	386.0	COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria,42SJI@68525|delta/epsilon subdivisions,2WPX2@28221|Deltaproteobacteria,2YV2D@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
MMD2_k127_2450673_3	627192.SLG_12400	3.373e-201	659.0	COG1629@1|root,COG4771@2|Bacteria,1R8R0@1224|Proteobacteria,2TTH0@28211|Alphaproteobacteria,2K0E8@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_2450673_18	1245469.S58_72080	2.248e-50	191.0	COG4403@1|root,COG4403@2|Bacteria,1NCPK@1224|Proteobacteria,2UJSZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2450673_16	261292.Nit79A3_2080	8.242e-55	199.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,373DM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
MMD2_k127_2450673_1	1278307.KB907015_gene3524	1.258e-212	676.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,2QIUB@267894|Psychromonadaceae	1236|Gammaproteobacteria	V	ABC transporter transmembrane region	draA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMD2_k127_2450673_7	1123253.AUBD01000001_gene1904	1.325e-125	409.0	COG0491@1|root,COG0491@2|Bacteria,1R4FA@1224|Proteobacteria,1S1QD@1236|Gammaproteobacteria,1X36I@135614|Xanthomonadales	135614|Xanthomonadales	S	metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_2450673_13	1068980.ARVW01000001_gene6963	3.048e-78	281.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria,4DYSS@85010|Pseudonocardiales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Laminin_G_3
MMD2_k127_2450673_21	1288494.EBAPG3_2760	8.356e-30	132.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria,371X2@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2450673_4	1297865.APJD01000003_gene6495	2.371e-182	589.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,3JX83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMD2_k127_2450673_22	234267.Acid_6849	6.978e-13	73.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,DHC
MMD2_k127_2450673_8	1121939.L861_07930	2.644e-120	402.0	COG1234@1|root,COG1234@2|Bacteria,1PPRD@1224|Proteobacteria,1RRV8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	CLP1_P,Lactamase_B,Lactamase_B_2
MMD2_k127_2450673_0	472759.Nhal_1958	5.654e-238	752.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,1TK7U@1236|Gammaproteobacteria,1X089@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8
MMD2_k127_2450673_12	543913.D521_2055	1.159e-79	277.0	COG0500@1|root,COG0500@2|Bacteria,1REJ2@1224|Proteobacteria,2VQ90@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMD2_k127_2450673_19	1298867.AUES01000001_gene1607	4.456e-40	152.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,3JQU4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD2_k127_2455324_0	1244869.H261_07588	2.452e-251	801.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2TU7G@28211|Alphaproteobacteria,2JQT9@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
MMD2_k127_2455324_3	865861.AZSU01000007_gene1119	6.684e-05	55.0	COG1752@1|root,COG1752@2|Bacteria,1UBYN@1239|Firmicutes,247V3@186801|Clostridia,36WRU@31979|Clostridiaceae	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMD2_k127_2455324_1	627192.SLG_27450	2.526e-14	75.0	2DBU1@1|root,2ZB3C@2|Bacteria,1NB4B@1224|Proteobacteria,2U0ZG@28211|Alphaproteobacteria,2K9YB@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2455324_2	627192.SLG_27450	2.037e-11	66.0	2DBU1@1|root,2ZB3C@2|Bacteria,1NB4B@1224|Proteobacteria,2U0ZG@28211|Alphaproteobacteria,2K9YB@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2466511_1	627192.SLG_27450	2.728e-87	308.0	2DBU1@1|root,2ZB3C@2|Bacteria,1NB4B@1224|Proteobacteria,2U0ZG@28211|Alphaproteobacteria,2K9YB@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2466511_0	649638.Trad_0190	2.207e-210	675.0	COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1WMCG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
MMD2_k127_2466511_2	401053.AciPR4_1212	3.55e-62	226.0	COG3303@1|root,COG3303@2|Bacteria,3Y999@57723|Acidobacteria,2JP5G@204432|Acidobacteriia	204432|Acidobacteriia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD2_k127_2466511_4	234267.Acid_7895	7.725e-11	76.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2466511_3	247633.GP2143_17796	2.012e-22	108.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2526915_5	1463917.JODC01000020_gene9238	1.66e-31	144.0	2AAD4@1|root,30ZP1@2|Bacteria,2HPD2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2526915_3	1215092.PA6_046_00220	1.772e-103	337.0	2DB76@1|root,2Z7JZ@2|Bacteria,1R41X@1224|Proteobacteria,1S1J8@1236|Gammaproteobacteria,1YIS6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
MMD2_k127_2526915_0	1234364.AMSF01000098_gene2648	2.513e-213	673.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,1RQUU@1236|Gammaproteobacteria,1X4D6@135614|Xanthomonadales	135614|Xanthomonadales	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
MMD2_k127_2526915_8	323261.Noc_1880	2.6e-06	52.0	2EKYG@1|root,33EMZ@2|Bacteria,1NJ4M@1224|Proteobacteria,1SH0U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2526915_2	522306.CAP2UW1_3680	4.022e-106	363.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KQCV@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD2_k127_2526915_4	1304885.AUEY01000002_gene343	6.561e-34	141.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria,2MJZ5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMD2_k127_2526915_1	1144305.PMI02_00293	5.599e-150	492.0	COG5297@1|root,COG5297@2|Bacteria,1NNDR@1224|Proteobacteria,2U2XN@28211|Alphaproteobacteria,2K31U@204457|Sphingomonadales	204457|Sphingomonadales	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
MMD2_k127_2526915_6	1396418.BATQ01000050_gene314	1.246e-18	97.0	2EMN6@1|root,33FAI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2526915_7	450851.PHZ_c3077	4.552e-15	83.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2569894_1	1500890.JQNL01000001_gene2091	1.031e-140	460.0	28WRE@1|root,2ZIR3@2|Bacteria,1QDI8@1224|Proteobacteria,1SMDH@1236|Gammaproteobacteria,1X4JH@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
MMD2_k127_2569894_5	316273.XCV2949	1.345e-43	160.0	COG0640@1|root,COG0640@2|Bacteria,1MZ5G@1224|Proteobacteria,1SEWK@1236|Gammaproteobacteria,1X80E@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMD2_k127_2569894_0	1144312.PMI09_03647	1.855e-190	597.0	COG2141@1|root,COG2141@2|Bacteria,1N899@1224|Proteobacteria,2TTZ7@28211|Alphaproteobacteria,4BBF8@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	MA20_21690	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMD2_k127_2569894_7	555793.WSK_1442	9.419e-14	82.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2569894_8	555793.WSK_3324	4.227e-11	74.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2569894_2	251221.35213336	1.275e-107	355.0	COG1718@1|root,COG1718@2|Bacteria,1G3HN@1117|Cyanobacteria	1117|Cyanobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2569894_4	272134.KB731324_gene5504	3.8e-48	176.0	2CP0Z@1|root,32SI8@2|Bacteria,1G5TF@1117|Cyanobacteria,1HB85@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
MMD2_k127_2569894_6	555793.WSK_1442	3.816e-14	85.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2569894_3	1254432.SCE1572_03845	8.069e-98	327.0	COG3570@1|root,COG3570@2|Bacteria,1MW4R@1224|Proteobacteria	1224|Proteobacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	str	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
MMD2_k127_2587703_5	472759.Nhal_1884	7.258e-77	263.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WZYK@135613|Chromatiales	135613|Chromatiales	H	Belongs to the RtcB family	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
MMD2_k127_2587703_10	1123354.AUDR01000015_gene351	1.085e-51	186.0	COG1371@1|root,COG1371@2|Bacteria	2|Bacteria	J	PFAM Archease protein family (DUF101 UPF0211)	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease
MMD2_k127_2587703_7	357804.Ping_2701	1.39e-62	226.0	COG1278@1|root,COG1544@1|root,COG1278@2|Bacteria,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,1S5AA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	PFAM Cold-shock protein, DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
MMD2_k127_2587703_12	314278.NB231_01194	8.912e-27	113.0	2E600@1|root,3315C@2|Bacteria,1NB48@1224|Proteobacteria,1SD2Y@1236|Gammaproteobacteria,1X1WR@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2587703_13	435908.IDSA_09690	1.04e-22	107.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,2QGEF@267893|Idiomarinaceae	1236|Gammaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
MMD2_k127_2587703_4	2340.JV46_19800	1.009e-92	314.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,1RRQ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Helix-hairpin-helix domain	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_5,HHH_8
MMD2_k127_2587703_15	1280947.HY30_05255	3.294e-21	98.0	298YE@1|root,2ZW29@2|Bacteria,1N9JF@1224|Proteobacteria,2UHRA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2587703_11	311402.Avi_7426	1.046e-32	146.0	COG2079@1|root,COG2079@2|Bacteria,1PMKJ@1224|Proteobacteria,2V07A@28211|Alphaproteobacteria,4BDIS@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMD2_k127_2587703_6	113395.AXAI01000013_gene6737	4.85e-68	261.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2TRBF@28211|Alphaproteobacteria,3JXPV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4
MMD2_k127_2587703_17	396588.Tgr7_1585	9.208e-17	88.0	COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMD2_k127_2587703_14	713586.KB900536_gene2827	3.16e-22	104.0	COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMD2_k127_2587703_2	251221.35211907	1.351e-190	614.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1G4JM@1117|Cyanobacteria	1117|Cyanobacteria	P	TrkA-N domain	-	-	-	ko:K11745	-	-	-	-	ko00000,ko02000	2.A.37.1.1	-	-	Na_H_Exchanger,TrkA_N
MMD2_k127_2587703_9	1396141.BATP01000025_gene923	4.757e-60	213.0	COG2249@1|root,COG2249@2|Bacteria,46VHD@74201|Verrucomicrobia,2IUV1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
MMD2_k127_2587703_1	234267.Acid_7735	7.841e-223	701.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD2_k127_2587703_0	1267535.KB906767_gene491	3.276e-237	749.0	COG0367@1|root,COG0367@2|Bacteria,3Y6CC@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
MMD2_k127_2587703_8	627192.SLG_31390	2.313e-61	228.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
MMD2_k127_260130_1	1121937.AUHJ01000002_gene3600	3.101e-250	785.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4664R@72275|Alteromonadaceae	1236|Gammaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
MMD2_k127_260130_0	518766.Rmar_1656	2.989e-291	918.0	COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	2.7.2.4,4.1.1.20	ko:K00928,ko:K12526	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00451,R00480	RC00002,RC00043,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC
MMD2_k127_260130_3	702113.PP1Y_AT12375	1.075e-101	346.0	COG4188@1|root,COG4188@2|Bacteria,1NAS2@1224|Proteobacteria,2UPBC@28211|Alphaproteobacteria,2K3SY@204457|Sphingomonadales	204457|Sphingomonadales	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_260130_7	1104324.P186_2420	1.38e-18	91.0	COG0140@1|root,arCOG02677@2157|Archaea,2XRAD@28889|Crenarchaeota	28889|Crenarchaeota	E	phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
MMD2_k127_260130_2	767434.Fraau_1741	9.359e-112	366.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1X39D@135614|Xanthomonadales	135614|Xanthomonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMD2_k127_260130_4	1384054.N790_03510	4.514e-68	239.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1X3ZJ@135614|Xanthomonadales	135614|Xanthomonadales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMD2_k127_260130_5	1234364.AMSF01000016_gene1669	1.178e-64	231.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1X5IB@135614|Xanthomonadales	135614|Xanthomonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMD2_k127_260130_6	666685.R2APBS1_1367	2.486e-43	159.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1X38F@135614|Xanthomonadales	135614|Xanthomonadales	E	Histidine biosynthesis bifunctional protein HisB	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
MMD2_k127_2637466_1	234267.Acid_7271	1.378e-102	347.0	COG0421@1|root,COG0421@2|Bacteria,3Y6UP@57723|Acidobacteria	57723|Acidobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
MMD2_k127_2637466_2	1123248.KB893316_gene4659	1.526e-80	275.0	COG2249@1|root,COG2249@2|Bacteria,4NMQV@976|Bacteroidetes,1IRT3@117747|Sphingobacteriia	976|Bacteroidetes	S	Flavodoxin-like fold	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
MMD2_k127_2637466_0	748247.AZKH_3902	1.179e-260	818.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,2KVA6@206389|Rhodocyclales	206389|Rhodocyclales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
MMD2_k127_2685683_19	1439940.BAY1663_04857	1.951e-18	87.0	COG2085@1|root,COG2085@2|Bacteria,1RCXR@1224|Proteobacteria,1S463@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NADP oxidoreductase, coenzyme f420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
MMD2_k127_2685683_16	446470.Snas_6367	1.688e-68	250.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4EY23@85014|Glycomycetales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF
MMD2_k127_2685683_14	575540.Isop_2778	5.539e-77	274.0	COG1519@1|root,COG1519@2|Bacteria,2IYCJ@203682|Planctomycetes	203682|Planctomycetes	M	transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
MMD2_k127_2685683_6	1313301.AUGC01000003_gene2099	1.893e-132	426.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the KdsA family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
MMD2_k127_2685683_7	313606.M23134_07710	2.712e-132	430.0	COG0176@1|root,COG2905@1|root,COG0176@2|Bacteria,COG2905@2|Bacteria,4NIUX@976|Bacteroidetes,47KKQ@768503|Cytophagia	976|Bacteroidetes	GT	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,TAL_FSA
MMD2_k127_2685683_17	313606.M23134_07460	6.188e-63	223.0	COG1778@1|root,COG1778@2|Bacteria,4NMFZ@976|Bacteroidetes,47PAE@768503|Cytophagia	976|Bacteroidetes	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	-
MMD2_k127_2685683_5	472759.Nhal_3504	2.665e-134	449.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1WX73@135613|Chromatiales	135613|Chromatiales	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N,Kdo
MMD2_k127_2685683_0	323848.Nmul_A1487	1.622e-243	780.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VIAP@28216|Betaproteobacteria,37259@32003|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMD2_k127_2685683_15	1340493.JNIF01000003_gene3476	1.397e-75	276.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
MMD2_k127_2685683_8	472759.Nhal_3357	8.664e-124	426.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1WXK2@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_2685683_9	1265313.HRUBRA_00800	2.616e-117	400.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5FS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_2685683_12	1121403.AUCV01000036_gene2936	2.122e-84	286.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42NBA@68525|delta/epsilon subdivisions,2X5CP@28221|Deltaproteobacteria,2MJJB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_2685683_10	472759.Nhal_3354	1.012e-116	387.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1WXMI@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
MMD2_k127_2685683_3	1469245.JFBG01000070_gene44	2.224e-141	457.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMD2_k127_2685683_1	85643.Tmz1t_1473	2.316e-182	595.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
MMD2_k127_2685683_2	1510531.JQJJ01000008_gene4081	6.571e-176	562.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,3JQS8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.96	ko:K16871	ko00250,ko00650,ko01100,ko01120,map00250,map00650,map01100,map01120	M00027	R10178	RC00008,RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_3
MMD2_k127_2685683_11	452637.Oter_2237	1.601e-101	342.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMD2_k127_2685683_20	452637.Oter_2236	8.445e-16	79.0	COG4877@1|root,COG4877@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
MMD2_k127_2685683_18	234267.Acid_1337	9.218e-57	210.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
MMD2_k127_2685683_4	5671.XP_001469133.1	5.83e-136	450.0	COG0626@1|root,KOG0053@2759|Eukaryota,3XT9E@5653|Kinetoplastida	5653|Kinetoplastida	E	cystathione gamma lyase	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
MMD2_k127_2685683_13	550540.Fbal_2581	2.16e-80	282.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	mdeA	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMD2_k127_2689883_1	903818.KI912268_gene3208	6.147e-105	352.0	COG1472@1|root,COG1472@2|Bacteria,3Y2YR@57723|Acidobacteria	57723|Acidobacteria	G	PFAM glycoside hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
MMD2_k127_2689883_5	639030.JHVA01000001_gene1885	1.753e-11	70.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2689883_4	911045.PSE_1792	7.096e-19	93.0	COG1846@1|root,COG1846@2|Bacteria,1RFUJ@1224|Proteobacteria,2U84N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMD2_k127_2689883_2	1379270.AUXF01000004_gene2917	7.247e-50	196.0	COG1228@1|root,COG1228@2|Bacteria,1ZUSA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD2_k127_2689883_3	267608.RSc2495	1.472e-48	187.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2VN9Y@28216|Betaproteobacteria,1K6AS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
MMD2_k127_2689883_0	243231.GSU2758	0.0	1427.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42P3V@68525|delta/epsilon subdivisions,2WKWV@28221|Deltaproteobacteria,43TF0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMD2_k127_270084_57	1254432.SCE1572_16030	1.122e-07	54.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMD2_k127_270084_1	1122137.AQXF01000004_gene1584	8.241e-255	805.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U1C8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_270084_54	931627.MycrhDRAFT_6044	1.053e-11	73.0	COG4319@1|root,COG4319@2|Bacteria,2INEA@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMD2_k127_270084_9	1415778.JQMM01000001_gene260	5.621e-174	557.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
MMD2_k127_270084_22	1238450.VIBNISOn1_280040	1.887e-86	295.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1XT4A@135623|Vibrionales	135623|Vibrionales	G	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
MMD2_k127_270084_26	697281.Mahau_1312	2.286e-76	262.0	COG0637@1|root,COG0637@2|Bacteria,1V1NW@1239|Firmicutes,24G37@186801|Clostridia,42G6E@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,HAD_2
MMD2_k127_270084_32	1232453.BAIF02000008_gene2985	1.413e-55	206.0	COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia	186801|Clostridia	S	Dihydroxyacetone kinase, L subunit	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
MMD2_k127_270084_13	1121924.ATWH01000011_gene250	1.801e-141	467.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4FRC5@85023|Microbacteriaceae	201174|Actinobacteria	G	Dak1 domain	dhaK2	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
MMD2_k127_270084_35	765912.Thimo_3651	1.372e-42	172.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1WWPE@135613|Chromatiales	135613|Chromatiales	G	HAD-superfamily hydrolase, subfamily IA, variant 3	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMD2_k127_270084_33	247633.GP2143_17796	4.681e-44	175.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_3	234267.Acid_4918	5.261e-209	672.0	COG4993@1|root,COG4993@2|Bacteria,3Y6BH@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
MMD2_k127_270084_15	504472.Slin_1529	1.057e-121	409.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,47MRG@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
MMD2_k127_270084_38	247633.GP2143_17796	2.324e-39	164.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_7	627192.SLG_04410	2.502e-184	600.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K1V6@204457|Sphingomonadales	204457|Sphingomonadales	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
MMD2_k127_270084_28	247633.GP2143_18121	9.661e-74	259.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_40	551789.ATVJ01000001_gene1039	2.249e-37	146.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_10	1207063.P24_16487	3.046e-160	515.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,2JPXJ@204441|Rhodospirillales	204441|Rhodospirillales	C	Cysteine-rich domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
MMD2_k127_270084_24	1121033.AUCF01000008_gene5740	3.525e-82	299.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2TRA7@28211|Alphaproteobacteria,2JPFB@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
MMD2_k127_270084_2	392499.Swit_0991	5.77e-222	699.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSG6@28211|Alphaproteobacteria,2K2GG@204457|Sphingomonadales	204457|Sphingomonadales	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMD2_k127_270084_21	2340.JV46_24970	2.613e-90	310.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RQGQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
MMD2_k127_270084_46	1121937.AUHJ01000009_gene1477	6.185e-32	132.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,1SZWN@1236|Gammaproteobacteria,46CZV@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
MMD2_k127_270084_42	671143.DAMO_1116	2.024e-36	151.0	COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria	2|Bacteria	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
MMD2_k127_270084_18	1123073.KB899241_gene2783	4.621e-98	339.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1T1KQ@1236|Gammaproteobacteria,1XDAK@135614|Xanthomonadales	135614|Xanthomonadales	T	Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
MMD2_k127_270084_29	1123073.KB899241_gene2782	1.889e-72	252.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RPNH@1236|Gammaproteobacteria,1X4VA@135614|Xanthomonadales	135614|Xanthomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_270084_47	396588.Tgr7_2924	1.11e-23	103.0	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the bacterial histone-like protein family	VL23_14575	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
MMD2_k127_270084_30	998674.ATTE01000001_gene3092	2.355e-66	236.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
MMD2_k127_270084_0	1442599.JAAN01000005_gene951	4.569e-261	815.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1X3WE@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
MMD2_k127_270084_20	1123253.AUBD01000016_gene1970	1.072e-92	309.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1X3EF@135614|Xanthomonadales	135614|Xanthomonadales	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
MMD2_k127_270084_51	999141.GME_00130	9.104e-13	69.0	COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria,1XMQT@135619|Oceanospirillales	135619|Oceanospirillales	O	Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
MMD2_k127_270084_19	1033802.SSPSH_002860	4.096e-96	324.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	iJN746.PP_4253	Cytochrome_CBB3,FixP_N
MMD2_k127_270084_52	1045855.DSC_08250	1.931e-12	72.0	2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria,1SGKH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_5	187272.Mlg_1877	2.479e-187	595.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM cytochrome c oxidase accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
MMD2_k127_270084_49	292415.Tbd_0638	9.466e-14	85.0	COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,2VTYE@28216|Betaproteobacteria,1KRV3@119069|Hydrogenophilales	119069|Hydrogenophilales	S	FixH	-	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
MMD2_k127_270084_6	1415780.JPOG01000001_gene2437	2.89e-187	624.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X32B@135614|Xanthomonadales	135614|Xanthomonadales	P	COG2217 Cation transport ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
MMD2_k127_270084_56	1415780.JPOG01000001_gene2436	2.075e-10	73.0	COG3197@1|root,COG3197@2|Bacteria,1QSIT@1224|Proteobacteria,1RW0B@1236|Gammaproteobacteria,1X8QU@135614|Xanthomonadales	135614|Xanthomonadales	P	Cytochrome oxidase maturation protein	-	-	-	-	-	-	-	-	-	-	-	-	FixS
MMD2_k127_270084_43	545276.KB898734_gene2345	3.694e-36	147.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1WXWD@135613|Chromatiales	135613|Chromatiales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
MMD2_k127_270084_58	1123279.ATUS01000001_gene1570	9.638e-07	58.0	2EQ70@1|root,33HT9@2|Bacteria,1NIHT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_4	627192.SLG_31810	1.65e-194	644.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2K3KA@204457|Sphingomonadales	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_270084_25	485918.Cpin_3132	1.228e-81	291.0	COG3182@1|root,COG3182@2|Bacteria,4NIWJ@976|Bacteroidetes,1IS7U@117747|Sphingobacteriia	976|Bacteroidetes	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
MMD2_k127_270084_27	1163617.SCD_n01106	3.583e-76	265.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the MtfA family	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
MMD2_k127_270084_12	1054213.HMPREF9946_03253	7.359e-144	461.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,2JS0P@204441|Rhodospirillales	204441|Rhodospirillales	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMD2_k127_270084_45	1071679.BG57_28960	3.774e-32	133.0	2B41E@1|root,31WRS@2|Bacteria,1P8VA@1224|Proteobacteria,2VSE9@28216|Betaproteobacteria,1K0YA@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_14	471857.Svir_23590	3.471e-141	461.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4E0JF@85010|Pseudonocardiales	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMD2_k127_270084_59	420324.KI911965_gene668	0.0009658	51.0	2CBFC@1|root,32RYI@2|Bacteria,1N0T4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_50	702113.PP1Y_Mpl6566	1.536e-13	82.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,2KCBM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_11	1038859.AXAU01000001_gene3142	3.42e-156	499.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,3JV4V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMD2_k127_270084_39	247633.GP2143_17796	2.748e-39	166.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_55	1144275.COCOR_03911	1.747e-10	74.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SA7@68525|delta/epsilon subdivisions,2WNRU@28221|Deltaproteobacteria,2YU91@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
MMD2_k127_270084_34	1116472.MGMO_58c00080	3.172e-43	171.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,1RP40@1236|Gammaproteobacteria,1XEQI@135618|Methylococcales	135618|Methylococcales	G	Arylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMD2_k127_270084_48	555793.WSK_2000	9.854e-20	94.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_270084_23	330214.NIDE3764	2.954e-83	286.0	28PNA@1|root,2ZCB3@2|Bacteria	2|Bacteria	S	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
MMD2_k127_270084_44	485918.Cpin_5772	4.595e-35	139.0	COG2259@1|root,31BQE@2|Bacteria,4NQH2@976|Bacteroidetes,1ITDX@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
MMD2_k127_270084_17	290397.Adeh_2184	9.124e-102	336.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2YW96@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMD2_k127_270084_41	1397528.Q671_06585	4.155e-37	145.0	COG1226@1|root,31669@2|Bacteria,1RIW0@1224|Proteobacteria,1S6HC@1236|Gammaproteobacteria,1XMBE@135619|Oceanospirillales	135619|Oceanospirillales	P	Kef-type K transport systems	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
MMD2_k127_270084_36	742159.HMPREF0004_1855	3.289e-41	160.0	2DMP1@1|root,32SS8@2|Bacteria,1N0XZ@1224|Proteobacteria,2VRVN@28216|Betaproteobacteria,3T3V1@506|Alcaligenaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
MMD2_k127_270084_16	159087.Daro_3911	3.636e-107	353.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KV15@206389|Rhodocyclales	206389|Rhodocyclales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
MMD2_k127_270084_31	379066.GAU_3132	5.38e-63	222.0	2CDAN@1|root,3134Z@2|Bacteria,1ZU58@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
MMD2_k127_270084_8	379066.GAU_3131	2.162e-180	571.0	COG2303@1|root,COG2303@2|Bacteria,1ZSZW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMD2_k127_2726551_4	1333998.M2A_0825	1.515e-166	534.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,4BPBI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMD2_k127_2726551_8	1150626.PHAMO_320029	1.764e-138	451.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,2JPD3@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
MMD2_k127_2726551_17	1158756.AQXQ01000007_gene269	2.735e-46	172.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,1WXGS@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
MMD2_k127_2726551_1	1122604.JONR01000025_gene4590	3.895e-281	877.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1X45G@135614|Xanthomonadales	135614|Xanthomonadales	E	Acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMD2_k127_2726551_5	402881.Plav_0033	3.31e-165	530.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,1JN20@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class-III	bioA	-	2.6.1.18,2.6.1.62	ko:K00822,ko:K00833	ko00280,ko00410,ko00640,ko00780,ko01100,map00280,map00410,map00640,map00780,map01100	M00123,M00573,M00577	R00907,R03231,R04187	RC00006,RC00008,RC00062,RC00160,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMD2_k127_2726551_24	1158292.JPOE01000002_gene1941	2.177e-25	108.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2726551_3	1123279.ATUS01000006_gene3366	5.83e-200	639.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1J51M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG1109 Phosphomannomutase	xanA	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMD2_k127_2726551_10	1123392.AQWL01000007_gene1007	3.028e-117	412.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,1KRY7@119069|Hydrogenophilales	119069|Hydrogenophilales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
MMD2_k127_2726551_0	883078.HMPREF9695_00636	7.461e-316	986.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2U0IK@28211|Alphaproteobacteria,3JTMI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMD2_k127_2726551_30	83406.HDN1F_17280	0.0003037	48.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,1J81D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
MMD2_k127_2726551_25	1217710.F969_01164	8.443e-18	84.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,3NKKZ@468|Moraxellaceae	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
MMD2_k127_2726551_23	883126.HMPREF9710_03036	4.098e-29	121.0	2CKE6@1|root,32ZEV@2|Bacteria,1NBRM@1224|Proteobacteria,2VX50@28216|Betaproteobacteria,477T3@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Family of unknown function (DUF5329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5329
MMD2_k127_2726551_28	1121123.AUAO01000002_gene403	5.922e-15	79.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_2726551_29	1124780.ANNU01000002_gene1502	7.658e-10	61.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	spoIVFA	-	-	ko:K06194,ko:K06401,ko:K21472,ko:K21473	-	-	-	-	ko00000,ko01000,ko01002,ko01011	1.A.34.1.2	-	-	LysM,Peptidase_M23
MMD2_k127_2726551_19	1211114.ALIP01000061_gene2392	1.966e-36	147.0	COG0739@1|root,COG0739@2|Bacteria,1N6IQ@1224|Proteobacteria	1224|Proteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMD2_k127_2726551_22	639030.JHVA01000001_gene3130	7.599e-30	126.0	2BIJA@1|root,32CS2@2|Bacteria,3Y9DG@57723|Acidobacteria	57723|Acidobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
MMD2_k127_2726551_9	395964.KE386496_gene1447	1.692e-137	448.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TTAK@28211|Alphaproteobacteria,3NAEJ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_2726551_16	1220535.IMCC14465_03800	7.837e-48	186.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2U5AJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.197,6.3.3.3	ko:K01935,ko:K02169	ko00780,ko01100,map00780,map01100	M00123,M00572,M00573,M00577	R03182,R09543	RC00003,RC00460,RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
MMD2_k127_2726551_26	1117647.M5M_19030	8.678e-18	93.0	COG2885@1|root,COG2885@2|Bacteria,1RIG3@1224|Proteobacteria,1S5WW@1236|Gammaproteobacteria,1JAQP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
MMD2_k127_2726551_14	1265313.HRUBRA_00927	1.045e-61	221.0	COG0811@1|root,COG0811@2|Bacteria,1NXZ9@1224|Proteobacteria,1S154@1236|Gammaproteobacteria,1J4YC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0811 Biopolymer transport proteins	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
MMD2_k127_2726551_12	566466.NOR53_416	1.239e-83	293.0	COG2304@1|root,COG2304@2|Bacteria,1QBPM@1224|Proteobacteria,1RQIU@1236|Gammaproteobacteria,1J4PZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Secreted protein, containing von Willebrand factor (VWF) type	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2726551_11	1121937.AUHJ01000017_gene3005	9.285e-85	294.0	COG1196@1|root,COG1196@2|Bacteria,1R4BS@1224|Proteobacteria,1S13B@1236|Gammaproteobacteria,466JA@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
MMD2_k127_2726551_31	29306.JOBE01000001_gene2600	0.0003548	53.0	COG1716@1|root,COG1716@2|Bacteria,2HPF7@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,FHA
MMD2_k127_2726551_20	1415778.JQMM01000001_gene1137	1.8e-33	147.0	2ASXF@1|root,31ID0@2|Bacteria,1RM30@1224|Proteobacteria,1S8I2@1236|Gammaproteobacteria,1JAB6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2726551_7	1415778.JQMM01000001_gene1140	1.584e-155	524.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,1J55S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
MMD2_k127_2726551_15	1415778.JQMM01000001_gene1141	1.815e-55	213.0	COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,1J5XV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
MMD2_k127_2726551_27	38727.Pavir.J20020.1.p	8.625e-16	89.0	KOG0198@1|root,KOG0198@2759|Eukaryota,37M7U@33090|Viridiplantae,3G85M@35493|Streptophyta,3KT6Y@4447|Liliopsida,3I7Z2@38820|Poales	35493|Streptophyta	T	belongs to the protein kinase superfamily	-	-	-	ko:K20716	ko04016,map04016	-	-	-	ko00000,ko00001,ko01001	-	-	-	Pkinase
MMD2_k127_2726551_13	1415779.JOMH01000001_gene183	3.43e-73	263.0	28MBM@1|root,2ZAQ2@2|Bacteria,1R5V6@1224|Proteobacteria,1S0K0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_2726551_18	1245471.PCA10_03110	3.951e-44	166.0	2CD0I@1|root,32RWS@2|Bacteria,1N0MC@1224|Proteobacteria,1SABW@1236|Gammaproteobacteria,1YG8G@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
MMD2_k127_2726551_6	460265.Mnod_2756	1.344e-156	499.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,1JRZF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	cysB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD2_k127_2726551_21	523791.Kkor_1591	2.204e-30	132.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,1XS8J@135619|Oceanospirillales	135619|Oceanospirillales	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
MMD2_k127_2726551_2	338963.Pcar_0355	6.546e-272	851.0	COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,42Q4W@68525|delta/epsilon subdivisions,2WJ9H@28221|Deltaproteobacteria,43UJ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Squalene-hopene cyclase C-terminal domain	shc-1	-	4.2.1.129,5.4.99.17,5.4.99.7	ko:K01852,ko:K06045	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	M00101	R03199,R07322,R07323	RC00874,RC01850,RC01851	ko00000,ko00001,ko00002,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
MMD2_k127_2786593_2	1122604.JONR01000004_gene814	3.34e-69	236.0	COG3791@1|root,COG3791@2|Bacteria,1RCYS@1224|Proteobacteria,1S3X0@1236|Gammaproteobacteria,1X6FP@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMD2_k127_2786593_0	1449076.JOOE01000002_gene955	7.647e-156	502.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,2K18M@204457|Sphingomonadales	204457|Sphingomonadales	C	Dehydrogenase	lldD	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
MMD2_k127_2786593_1	1380394.JADL01000012_gene841	3.703e-110	382.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2U10C@28211|Alphaproteobacteria,2JVTY@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
MMD2_k127_2786593_3	1380394.JADL01000004_gene5989	3.143e-52	197.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2TSUU@28211|Alphaproteobacteria,2JWNR@204441|Rhodospirillales	204441|Rhodospirillales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
MMD2_k127_280662_3	1121033.AUCF01000013_gene1632	3.415e-70	256.0	COG0642@1|root,COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria,2JR29@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,dCache_1
MMD2_k127_280662_2	754476.Q7A_2721	6.553e-80	284.0	COG0642@1|root,COG0642@2|Bacteria,1R514@1224|Proteobacteria,1T1FM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMD2_k127_280662_1	1384054.N790_08670	2.239e-88	297.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1X41P@135614|Xanthomonadales	135614|Xanthomonadales	KT	XRE family transcriptional regulator	VL23_03445	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_280662_4	754476.Q7A_2723	9.026e-52	199.0	COG1538@1|root,COG1538@2|Bacteria,1RDXS@1224|Proteobacteria,1SZYV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD2_k127_280662_5	768671.ThimaDRAFT_2524	1.968e-40	171.0	COG0845@1|root,COG0845@2|Bacteria,1QN99@1224|Proteobacteria,1S0F7@1236|Gammaproteobacteria,1WXIQ@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMD2_k127_280662_0	243233.MCA2720	0.0	1290.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XEBY@135618|Methylococcales	135618|Methylococcales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
MMD2_k127_3027543_2	472759.Nhal_1884	3.956e-177	561.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WZYK@135613|Chromatiales	135613|Chromatiales	H	Belongs to the RtcB family	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
MMD2_k127_3027543_13	261292.Nit79A3_2700	1.347e-24	112.0	COG1531@1|root,COG1531@2|Bacteria,1N7PM@1224|Proteobacteria,2W6WU@28216|Betaproteobacteria,374JG@32003|Nitrosomonadales	28216|Betaproteobacteria	AJ	Protein of unknown function (DUF504)	-	-	-	-	-	-	-	-	-	-	-	-	DUF504
MMD2_k127_3027543_12	589865.DaAHT2_2130	1.799e-26	118.0	COG0517@1|root,COG0517@2|Bacteria,1QQRM@1224|Proteobacteria,42TVT@68525|delta/epsilon subdivisions,2WQBQ@28221|Deltaproteobacteria,2MNSD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMD2_k127_3027543_5	472759.Nhal_2962	1.863e-86	302.0	COG0462@1|root,COG0462@2|Bacteria,1QHJ7@1224|Proteobacteria,1RZJH@1236|Gammaproteobacteria,1WZXT@135613|Chromatiales	135613|Chromatiales	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
MMD2_k127_3027543_7	941449.dsx2_1908	8.107e-59	212.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,42N60@68525|delta/epsilon subdivisions,2WQCI@28221|Deltaproteobacteria,2MBPS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
MMD2_k127_3027543_4	1123354.AUDR01000015_gene349	1.002e-157	511.0	COG1488@1|root,COG1488@2|Bacteria,1PNWY@1224|Proteobacteria,2W9DN@28216|Betaproteobacteria,1KS4Z@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	-	-	-	-	-	-	-	-	-	-	-	-	NAPRTase
MMD2_k127_3027543_6	314278.NB231_02593	6.517e-85	286.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,1RZBF@1236|Gammaproteobacteria,1X0F6@135613|Chromatiales	135613|Chromatiales	Q	PFAM isochorismatase hydrolase	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
MMD2_k127_3027543_0	1123256.KB907927_gene1628	1.121e-231	732.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RQ2G@1236|Gammaproteobacteria,1X3JK@135614|Xanthomonadales	135614|Xanthomonadales	O	Peptidase family M41	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMD2_k127_3027543_16	1446473.JHWH01000008_gene135	1.901e-07	64.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,2TT29@28211|Alphaproteobacteria,2PWKV@265|Paracoccus	28211|Alphaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.13.9,3.5.4.44	ko:K01271,ko:K15783	ko00260,ko01100,map00260,map01100	-	R09800	RC02661	ko00000,ko00001,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMD2_k127_3027543_9	1463857.JOFZ01000001_gene5318	3.73e-47	185.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	-	-	3.4.11.9,3.4.13.9,3.5.3.3,3.5.4.44	ko:K01262,ko:K01271,ko:K08688,ko:K15783	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566,R09800	RC00548,RC00549,RC02661	ko00000,ko00001,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMD2_k127_3027543_3	1356854.N007_10715	5.277e-176	569.0	COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,4HBKB@91061|Bacilli	91061|Bacilli	EQ	COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMD2_k127_3027543_14	1356854.N007_10720	8.26e-24	117.0	COG0146@1|root,COG0146@2|Bacteria	2|Bacteria	EQ	ligase activity	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMD2_k127_3027543_1	935840.JAEQ01000004_gene641	1.449e-201	648.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,43HM4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMD2_k127_3027543_8	1550073.JROH01000003_gene2362	2.606e-52	212.0	COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1R8HM@1224|Proteobacteria,2U3RH@28211|Alphaproteobacteria,2KCYK@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_3027543_11	1472418.BBJC01000004_gene1788	2.083e-31	137.0	2CBAE@1|root,31814@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3027543_18	316056.RPC_0328	0.0009606	50.0	28JYF@1|root,2Z9NQ@2|Bacteria,1MXUQ@1224|Proteobacteria,2TS50@28211|Alphaproteobacteria,3JV8F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	MA20_24600	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3027543_15	1125863.JAFN01000001_gene3142	1.224e-18	98.0	COG0671@1|root,COG0671@2|Bacteria,1QUKE@1224|Proteobacteria,42XAW@68525|delta/epsilon subdivisions,2WSJV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
MMD2_k127_3027543_10	312309.VF_0040	2.482e-32	138.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1SN55@1236|Gammaproteobacteria,1XSZP@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD2_k127_3027543_17	76114.ebA1369	3.075e-07	52.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK32@28216|Betaproteobacteria,2KZRT@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD2_k127_3084186_13	1123261.AXDW01000001_gene1485	1.348e-35	137.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XCD8@135614|Xanthomonadales	135614|Xanthomonadales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
MMD2_k127_3084186_2	1415778.JQMM01000001_gene335	3.335e-184	587.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4KR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	prsR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD2_k127_3084186_4	383372.Rcas_0781	8.69e-133	434.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi,3772V@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMD2_k127_3084186_16	1121396.KB892946_gene2941	3.097e-08	67.0	COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,42SEP@68525|delta/epsilon subdivisions,2WPUA@28221|Deltaproteobacteria,2MK7X@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMD2_k127_3084186_12	290633.GOX0444	2.285e-36	151.0	COG0746@1|root,COG1977@1|root,COG0746@2|Bacteria,COG1977@2|Bacteria,1RKCH@1224|Proteobacteria	1224|Proteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,ThiS
MMD2_k127_3084186_15	1408444.JHYC01000008_gene1427	6.586e-12	66.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3084186_17	1158182.KB905020_gene2168	3.307e-07	54.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1WW94@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMD2_k127_3084186_11	272134.KB731324_gene1963	3.164e-63	223.0	COG2120@1|root,COG2120@2|Bacteria,1G3DM@1117|Cyanobacteria,1H7V9@1150|Oscillatoriales	1117|Cyanobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMD2_k127_3084186_7	1286631.X805_32130	2.227e-99	331.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VIQG@28216|Betaproteobacteria	28216|Betaproteobacteria	JM	Glucose-1-phosphate cytidylyltransferase	rfbF	-	2.7.7.33,2.7.7.71	ko:K00978,ko:K15669	ko00500,ko00520,ko00540,ko01100,map00500,map00520,map00540,map01100	-	R00956,R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
MMD2_k127_3084186_3	1510531.JQJJ01000008_gene3998	1.757e-145	469.0	COG0451@1|root,COG0451@2|Bacteria,1MV73@1224|Proteobacteria,2TU81@28211|Alphaproteobacteria,3JV3N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Polysaccharide biosynthesis protein	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMD2_k127_3084186_1	1095769.CAHF01000010_gene1298	1.569e-205	647.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria	1224|Proteobacteria	H	amine oxidase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
MMD2_k127_3084186_0	1095769.CAHF01000010_gene1297	5.287e-215	675.0	COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,2VQM9@28216|Betaproteobacteria	28216|Betaproteobacteria	E	homoserine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_3
MMD2_k127_3084186_9	1095769.CAHF01000010_gene1296	3.749e-76	258.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,472YX@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
MMD2_k127_3084186_10	1095769.CAHF01000010_gene1303	3.347e-65	231.0	28Q55@1|root,2ZCN6@2|Bacteria,1P7CW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3084186_6	338969.Rfer_0691	2.117e-110	376.0	COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,2WEWR@28216|Betaproteobacteria,4AJNX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
MMD2_k127_3084186_14	1500894.JQNN01000001_gene3729	3.256e-14	85.0	2DPDG@1|root,331M7@2|Bacteria,1NJ43@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3084186_8	324602.Caur_1781	2.549e-79	275.0	2AJKK@1|root,31A7Q@2|Bacteria	2|Bacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,Methyltransf_22
MMD2_k127_3084186_5	1095769.CAHF01000010_gene1301	6.505e-111	362.0	2ART5@1|root,31H4G@2|Bacteria,1R86P@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3139999_33	1095769.CAHF01000005_gene1540	1.709e-12	77.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2VR28@28216|Betaproteobacteria,475GE@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	carboxymuconolactone decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMD2_k127_3139999_27	1038860.AXAP01000082_gene501	2.87e-29	135.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria,3JUX0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMD2_k127_3139999_17	519989.ECTPHS_09273	6.021e-73	267.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1WWEI@135613|Chromatiales	135613|Chromatiales	H	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
MMD2_k127_3139999_24	640081.Dsui_0119	3.941e-54	209.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,2KW1H@206389|Rhodocyclales	206389|Rhodocyclales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
MMD2_k127_3139999_5	1453501.JELR01000002_gene176	2.29e-147	490.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,464HV@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMD2_k127_3139999_18	648996.Theam_1220	5.452e-72	252.0	COG3264@1|root,COG3264@2|Bacteria	2|Bacteria	M	cellular water homeostasis	mscS	-	-	ko:K03442,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.2,1.A.23.3	-	-	MS_channel,TM_helix
MMD2_k127_3139999_20	1033802.SSPSH_001261	8.965e-63	244.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
MMD2_k127_3139999_30	1384054.N790_14370	7.664e-16	92.0	COG3017@1|root,COG3017@2|Bacteria,1PW07@1224|Proteobacteria,1RVWS@1236|Gammaproteobacteria,1X72U@135614|Xanthomonadales	135614|Xanthomonadales	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
MMD2_k127_3139999_6	765912.Thimo_3135	4.69e-140	451.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1WWSB@135613|Chromatiales	135613|Chromatiales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
MMD2_k127_3139999_22	396588.Tgr7_0528	9.659e-58	209.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1WYEN@135613|Chromatiales	135613|Chromatiales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
MMD2_k127_3139999_23	767434.Fraau_0603	2.661e-55	199.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1X40M@135614|Xanthomonadales	135614|Xanthomonadales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
MMD2_k127_3139999_4	1158146.KB907121_gene901	7.215e-150	481.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1WWWF@135613|Chromatiales	135613|Chromatiales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
MMD2_k127_3139999_28	1379270.AUXF01000002_gene1370	1.101e-27	124.0	COG0652@1|root,COG0652@2|Bacteria,1ZUVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
MMD2_k127_3139999_11	926550.CLDAP_03770	6.574e-106	355.0	COG0176@1|root,COG0176@2|Bacteria,2GA93@200795|Chloroflexi	200795|Chloroflexi	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
MMD2_k127_3139999_0	323261.Noc_2717	0.0	1270.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RPSW@1236|Gammaproteobacteria,1WVZE@135613|Chromatiales	135613|Chromatiales	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
MMD2_k127_3139999_12	105559.Nwat_2807	3.728e-105	355.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,1WWEE@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
MMD2_k127_3139999_16	1307759.JOMJ01000004_gene3107	8.171e-74	265.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,42RV4@68525|delta/epsilon subdivisions,2WP4W@28221|Deltaproteobacteria,2MBIY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMD2_k127_3139999_2	1232410.KI421421_gene3797	2.766e-299	947.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,43T5A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
MMD2_k127_3139999_15	215803.DB30_8825	5.708e-79	280.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2YVAF@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD2_k127_3139999_9	1123261.AXDW01000006_gene2406	1.334e-113	384.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RSEC@1236|Gammaproteobacteria,1X44S@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
MMD2_k127_3139999_10	288000.BBta_1794	6.196e-106	359.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2TSFB@28211|Alphaproteobacteria,3JRCB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1501)	MA20_05265	-	-	-	-	-	-	-	-	-	-	-	DUF1501
MMD2_k127_3139999_25	247633.GP2143_18126	3.318e-40	162.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3139999_13	509190.Cseg_0673	4.022e-105	373.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2KFCI@204458|Caulobacterales	204458|Caulobacterales	E	Prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
MMD2_k127_3139999_29	1279015.KB908470_gene207	7.83e-21	93.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,1SEIJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
MMD2_k127_3139999_8	1267535.KB906767_gene1411	1.123e-120	407.0	COG1506@1|root,COG1506@2|Bacteria,3Y357@57723|Acidobacteria,2JIKY@204432|Acidobacteriia	204432|Acidobacteriia	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
MMD2_k127_3139999_3	1267535.KB906767_gene5326	3.943e-176	561.0	COG2010@1|root,COG2010@2|Bacteria,3Y650@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3,Paired_CXXCH_1
MMD2_k127_3139999_14	391038.Bphy_5138	7.831e-85	291.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VKAX@28216|Betaproteobacteria,1K3UW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Chromate resistance	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
MMD2_k127_3139999_21	322710.Avin_33890	1.69e-59	217.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,1RPXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	yfjR	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
MMD2_k127_3139999_1	234267.Acid_3297	1.217e-317	993.0	COG0577@1|root,COG0577@2|Bacteria,3Y41Z@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_3139999_31	1121930.AQXG01000002_gene2218	2.996e-15	82.0	COG5615@1|root,COG5615@2|Bacteria,4P6NC@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	CopD
MMD2_k127_3139999_7	204669.Acid345_0768	3.433e-131	454.0	COG0457@1|root,COG0457@2|Bacteria,3Y3D1@57723|Acidobacteria,2JM3V@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3139999_19	234267.Acid_3334	4.672e-71	259.0	COG3391@1|root,COG3391@2|Bacteria,3Y3R3@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
MMD2_k127_3139999_34	1056512.D515_01071	9.837e-06	57.0	COG4319@1|root,COG4319@2|Bacteria,1RIGF@1224|Proteobacteria,1S69W@1236|Gammaproteobacteria,1XXUP@135623|Vibrionales	135623|Vibrionales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMD2_k127_3139999_26	472759.Nhal_3186	2.297e-39	156.0	COG5502@1|root,COG5502@2|Bacteria,1NB8V@1224|Proteobacteria,1SETZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
MMD2_k127_3139999_35	402881.Plav_0741	9.693e-05	53.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD2_k127_3154088_4	1123023.JIAI01000004_gene8204	7.589e-95	316.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
MMD2_k127_3154088_17	28258.KP05_00265	2.092e-06	58.0	COG3637@1|root,COG3637@2|Bacteria,1RJMJ@1224|Proteobacteria,1S7PC@1236|Gammaproteobacteria,1XQHX@135619|Oceanospirillales	135619|Oceanospirillales	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_membrane
MMD2_k127_3154088_7	269799.Gmet_2594	2.24e-76	267.0	COG3240@1|root,COG3240@2|Bacteria,1MWDI@1224|Proteobacteria,42WSP@68525|delta/epsilon subdivisions,2WS6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
MMD2_k127_3154088_16	634499.EpC_16050	4.144e-07	53.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,3X5EA@551|Erwinia	1236|Gammaproteobacteria	EH	Para-aminobenzoate synthase component	pabB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_1977	Anth_synt_I_N,Chorismate_bind
MMD2_k127_3154088_8	1267535.KB906767_gene904	6.532e-62	222.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
MMD2_k127_3154088_13	298386.PBPRB0932	1.827e-32	140.0	COG1011@1|root,COG1011@2|Bacteria,1PGNF@1224|Proteobacteria,1RRDC@1236|Gammaproteobacteria,1XVRH@135623|Vibrionales	135623|Vibrionales	S	hydrolase (HAD superfamily)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
MMD2_k127_3154088_2	1179778.PMM47T1_12618	3.484e-126	412.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMD2_k127_3154088_9	1340493.JNIF01000003_gene4709	1.747e-60	228.0	2EQTB@1|root,33ID2@2|Bacteria	2|Bacteria	S	Lytic polysaccharide mono-oxygenase, cellulose-degrading	-	-	-	-	-	-	-	-	-	-	-	-	LPMO_10
MMD2_k127_3154088_12	682795.AciX8_3052	2.167e-35	151.0	COG3595@1|root,COG3595@2|Bacteria,3Y4HG@57723|Acidobacteria,2JJ7G@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
MMD2_k127_3154088_14	1144275.COCOR_03665	4.499e-28	132.0	COG5492@1|root,COG5492@2|Bacteria,1PBEQ@1224|Proteobacteria	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3154088_6	344747.PM8797T_05050	1.096e-79	273.0	COG3836@1|root,COG3836@2|Bacteria,2IX9H@203682|Planctomycetes	2|Bacteria	G	Belongs to the HpcH HpaI aldolase family	MA20_09190	-	2.7.7.38,4.1.2.20,4.1.2.52	ko:K00979,ko:K01630,ko:K02510	ko00053,ko00350,ko00540,ko01100,ko01120,map00053,map00350,map00540,map01100,map01120	M00063	R01645,R01647,R02754,R03277,R03351,R11396	RC00152,RC00307,RC00435,RC00572,RC00574,RC00910,RC03057	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HpcH_HpaI
MMD2_k127_3154088_1	670292.JH26_07495	1.731e-157	504.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2TTR7@28211|Alphaproteobacteria,1JS3T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM Luciferase-like monooxygenase	MA20_21365	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMD2_k127_3154088_11	1038858.AXBA01000023_gene446	2.677e-51	191.0	COG3531@1|root,COG3531@2|Bacteria,1RA76@1224|Proteobacteria,2U6DU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	DSBA-like thioredoxin domain	-	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	DSBA
MMD2_k127_3154088_0	713586.KB900536_gene124	0.0	1225.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
MMD2_k127_3154088_10	1500894.JQNN01000001_gene1627	1.192e-58	211.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,473C9@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
MMD2_k127_3154088_3	765912.Thimo_0732	5.007e-107	359.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales	135613|Chromatiales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
MMD2_k127_3154088_5	1123399.AQVE01000027_gene35	1.046e-81	276.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,4605I@72273|Thiotrichales	72273|Thiotrichales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
MMD2_k127_3154470_5	243233.MCA1804	1.245e-142	458.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XE5H@135618|Methylococcales	135618|Methylococcales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
MMD2_k127_3154470_8	1122604.JONR01000001_gene1846	5.071e-77	276.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1X3XY@135614|Xanthomonadales	135614|Xanthomonadales	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
MMD2_k127_3154470_1	396588.Tgr7_1182	8.116e-258	805.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
MMD2_k127_3154470_6	1049564.TevJSym_au00500	2.742e-123	407.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1J4QY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
MMD2_k127_3154470_2	1122604.JONR01000019_gene1192	8.506e-185	586.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1X2YM@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMD2_k127_3154470_14	935567.JAES01000034_gene1720	3.003e-18	88.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1X7C1@135614|Xanthomonadales	135614|Xanthomonadales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
MMD2_k127_3154470_7	472759.Nhal_2432	2.097e-98	334.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales	135613|Chromatiales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
MMD2_k127_3154470_9	396588.Tgr7_1433	4.058e-75	263.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1WX9P@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
MMD2_k127_3154470_10	314278.NB231_01424	5.799e-46	184.0	COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1WW55@135613|Chromatiales	135613|Chromatiales	DM	peptidase	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
MMD2_k127_3154470_15	349124.Hhal_0127	1.304e-14	79.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,1SD91@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
MMD2_k127_3154470_4	1121935.AQXX01000068_gene5863	1.305e-158	506.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1XHPA@135619|Oceanospirillales	135619|Oceanospirillales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMD2_k127_3154470_3	497321.C664_03485	1.119e-184	589.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,2KVEX@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMD2_k127_3154470_11	314278.NB231_01074	1.005e-35	151.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
MMD2_k127_3154470_16	1121861.KB899932_gene25	4.594e-07	62.0	COG5508@1|root,COG5508@2|Bacteria,1Q2RE@1224|Proteobacteria,2V9Z4@28211|Alphaproteobacteria,2JUM0@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1674)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1674
MMD2_k127_3154470_13	1304275.C41B8_09000	1.775e-28	118.0	COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,1SBDX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	succinate dehydrogenase	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMD2_k127_3154470_12	1415779.JOMH01000001_gene2984	2.184e-31	127.0	COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,1SAC6@1236|Gammaproteobacteria,1X7KQ@135614|Xanthomonadales	135614|Xanthomonadales	C	succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sdh_cyt
MMD2_k127_3154470_0	519989.ECTPHS_11050	5.414e-308	958.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales	135613|Chromatiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMD2_k127_3169201_6	134676.ACPL_6118	6.818e-65	229.0	COG2133@1|root,COG2133@2|Bacteria,2IDZQ@201174|Actinobacteria	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	gdhB	-	-	-	-	-	-	-	-	-	-	-	GSDH
MMD2_k127_3169201_1	1037409.BJ6T_30140	1.714e-161	529.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,3JTE8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	MA20_02675	-	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
MMD2_k127_3169201_3	1088721.NSU_4113	1.132e-74	263.0	KOG2391@1|root,3279X@2|Bacteria,1RHDJ@1224|Proteobacteria,2U9SJ@28211|Alphaproteobacteria,2KBN3@204457|Sphingomonadales	204457|Sphingomonadales	O	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3169201_8	627192.SLG_25160	5.998e-52	207.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3169201_7	1346791.M529_07235	4.962e-52	207.0	COG1917@1|root,COG1917@2|Bacteria,1NTJ5@1224|Proteobacteria,2UP17@28211|Alphaproteobacteria,2K9RX@204457|Sphingomonadales	204457|Sphingomonadales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD2_k127_3169201_5	113395.AXAI01000015_gene538	1.087e-65	237.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,3JW83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
MMD2_k127_3169201_4	1082931.KKY_82	5.093e-73	269.0	COG0596@1|root,COG0596@2|Bacteria,1QXD5@1224|Proteobacteria,2UNNR@28211|Alphaproteobacteria,3N93S@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3169201_2	313612.L8106_14825	5.409e-123	405.0	COG3239@1|root,COG3239@2|Bacteria,1G2GY@1117|Cyanobacteria,1H9RP@1150|Oscillatoriales	1117|Cyanobacteria	I	Fatty acid desaturase	desD	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	iJN678.desD_des6_	FA_desaturase
MMD2_k127_3169201_11	285535.JOEY01000127_gene5836	0.0003508	50.0	2DVJ7@1|root,33W53@2|Bacteria,2IJAU@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_3169201_10	1045009.AFXQ01000009_gene782	7.096e-07	59.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_3169201_0	1472716.KBK24_0109945	1.149e-186	597.0	COG1409@1|root,COG1409@2|Bacteria,1RHP4@1224|Proteobacteria,2WAH2@28216|Betaproteobacteria,1K35K@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
MMD2_k127_3178383_5	523791.Kkor_0247	4.514e-169	541.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XHUY@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
MMD2_k127_3178383_3	1384054.N790_08055	1.288e-188	606.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1X3IH@135614|Xanthomonadales	135614|Xanthomonadales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
MMD2_k127_3178383_18	754476.Q7A_131	1.106e-20	95.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,461ER@72273|Thiotrichales	72273|Thiotrichales	KL	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters	-	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
MMD2_k127_3178383_20	1234364.AMSF01000053_gene1323	3.327e-17	93.0	COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1X70Z@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4
MMD2_k127_3178383_11	768671.ThimaDRAFT_4018	1.133e-64	231.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1WX2W@135613|Chromatiales	135613|Chromatiales	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
MMD2_k127_3178383_1	631362.Thi970DRAFT_01167	2.094e-233	731.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1WWPY@135613|Chromatiales	135613|Chromatiales	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
MMD2_k127_3178383_14	590409.Dd586_0259	3.565e-44	172.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,2JDWA@204037|Dickeya	1236|Gammaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iYL1228.KPN_03664	Biotin_lipoyl
MMD2_k127_3178383_12	28258.KP05_03090	8.927e-53	191.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1XJM2@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
MMD2_k127_3178383_17	1260251.SPISAL_00615	6.706e-25	113.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,1WYFK@135613|Chromatiales	135613|Chromatiales	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
MMD2_k127_3178383_4	631362.Thi970DRAFT_01171	1.719e-185	608.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales	135613|Chromatiales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
MMD2_k127_3178383_16	497321.C664_19111	2.657e-28	119.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,2KX0I@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in tolerance to divalent cations	cutA1	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
MMD2_k127_3178383_15	396595.TK90_0291	5.833e-43	158.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1WYJ2@135613|Chromatiales	135613|Chromatiales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
MMD2_k127_3178383_0	395493.BegalDRAFT_0278	3.845e-267	831.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMD2_k127_3178383_2	713586.KB900536_gene1654	1.868e-227	738.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales	135613|Chromatiales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
MMD2_k127_3178383_19	1385515.N791_07955	2.306e-20	93.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria,1X821@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	VL23_05015	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
MMD2_k127_3178383_6	472759.Nhal_3503	9.582e-121	399.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,1X02A@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
MMD2_k127_3178383_8	76114.ebA3998	1.3e-108	366.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KVNC@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMD2_k127_3178383_13	1158165.KB898871_gene2107	4.585e-50	187.0	COG3642@1|root,COG3642@2|Bacteria,1QWT7@1224|Proteobacteria,1T2XM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
MMD2_k127_3178383_9	1255043.TVNIR_0563	3.326e-72	261.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1WVUX@135613|Chromatiales	135613|Chromatiales	M	Lipid A biosynthesis	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMD2_k127_3178383_10	713586.KB900536_gene1643	1.36e-67	242.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1WVUX@135613|Chromatiales	135613|Chromatiales	M	Lipid A biosynthesis	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMD2_k127_3178383_7	228410.NE1421	1.371e-114	377.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,372AH@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMD2_k127_3186307_9	1440052.EAKF1_ch1016	1.047e-17	88.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,3XQ1J@561|Escherichia	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
MMD2_k127_3186307_2	391615.ABSJ01000027_gene186	1.463e-94	323.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S1T4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,cNMP_binding
MMD2_k127_3186307_7	519989.ECTPHS_05831	1.254e-34	150.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1WY89@135613|Chromatiales	135613|Chromatiales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
MMD2_k127_3186307_3	1045855.DSC_02810	1.626e-87	303.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1X3WP@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMD2_k127_3186307_8	1265502.KB905943_gene2725	2.26e-32	130.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria,4ACUC@80864|Comamonadaceae	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
MMD2_k127_3186307_5	472759.Nhal_2446	2.081e-57	204.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1WX65@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
MMD2_k127_3186307_0	1123257.AUFV01000007_gene286	1.213e-143	465.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1X31N@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
MMD2_k127_3186307_6	1304275.C41B8_07582	4.5e-56	204.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
MMD2_k127_3186307_1	765912.Thimo_0344	6.535e-117	387.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales	135613|Chromatiales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
MMD2_k127_3186307_4	1117647.M5M_09875	5.02e-62	217.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1J5U0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
MMD2_k127_3280898_12	266264.Rmet_6425	9.26e-05	49.0	2AH8R@1|root,317IT@2|Bacteria,1PYVZ@1224|Proteobacteria,2WE0H@28216|Betaproteobacteria,1KBCY@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3280898_6	317025.Tcr_1409	1.749e-58	206.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,460KD@72273|Thiotrichales	72273|Thiotrichales	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
MMD2_k127_3280898_9	1266909.AUAG01000007_gene2318	8.364e-33	140.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1WY06@135613|Chromatiales	135613|Chromatiales	I	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
MMD2_k127_3280898_11	265072.Mfla_0776	2.703e-21	97.0	COG2913@1|root,COG3087@1|root,COG2913@2|Bacteria,COG3087@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,2KMV2@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA,SnoaL_3
MMD2_k127_3280898_7	236097.ADG881_1266	1.429e-55	197.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1XJKE@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMD2_k127_3280898_2	396588.Tgr7_0968	6.467e-143	477.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1WW15@135613|Chromatiales	135613|Chromatiales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
MMD2_k127_3280898_5	1123257.AUFV01000001_gene1954	1.213e-70	249.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1X4HU@135614|Xanthomonadales	135614|Xanthomonadales	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	ppnK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
MMD2_k127_3280898_3	1260251.SPISAL_04555	7.786e-110	366.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1WXB7@135613|Chromatiales	135613|Chromatiales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
MMD2_k127_3280898_8	1033802.SSPSH_002333	1.757e-33	138.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
MMD2_k127_3280898_0	472759.Nhal_3453	9e-323	997.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales	135613|Chromatiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
MMD2_k127_3280898_1	765910.MARPU_09850	9.482e-162	517.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1WWEM@135613|Chromatiales	135613|Chromatiales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMD2_k127_3280898_4	395494.Galf_2152	8.749e-105	346.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,44VID@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
MMD2_k127_3280898_10	580332.Slit_1052	6.944e-25	106.0	COG0515@1|root,COG0515@2|Bacteria,1NN82@1224|Proteobacteria,2VXXH@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3323841_22	748247.AZKH_p0281	1.073e-08	60.0	2E4CR@1|root,32Z86@2|Bacteria,1N7UZ@1224|Proteobacteria,2VVR1@28216|Betaproteobacteria,2KZJP@206389|Rhodocyclales	206389|Rhodocyclales	S	NADH-dependant formate dehydrogenase delta subunit FdsD	-	-	1.17.1.9	ko:K00126	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	FdsD
MMD2_k127_3323841_0	686340.Metal_1451	0.0	1518.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1XEFY@135618|Methylococcales	135618|Methylococcales	C	Formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMD2_k127_3323841_3	795666.MW7_2876	3.278e-238	746.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIGR@28216|Betaproteobacteria,1K3B8@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	fdsB	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMD2_k127_3323841_16	1283300.ATXB01000001_gene1026	2.085e-58	207.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,1XF7D@135618|Methylococcales	135618|Methylococcales	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	2Fe-2S_thioredx
MMD2_k127_3323841_19	1519464.HY22_08985	1.071e-25	114.0	2E6K6@1|root,3316Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3323841_5	1033802.SSPSH_000812	7.268e-160	526.0	COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	synthase	-	-	2.3.3.10	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
MMD2_k127_3323841_20	323848.Nmul_A2559	9.213e-24	109.0	COG2854@1|root,COG2854@2|Bacteria,1N275@1224|Proteobacteria,2WBHZ@28216|Betaproteobacteria,3735V@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	MlaC protein	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
MMD2_k127_3323841_18	396588.Tgr7_2685	4.986e-42	165.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1S92A@1236|Gammaproteobacteria,1WZ2D@135613|Chromatiales	135613|Chromatiales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
MMD2_k127_3323841_10	322710.Avin_20620	1.875e-103	349.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,1RZY2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
MMD2_k127_3323841_4	767434.Fraau_3204	8.451e-185	593.0	COG0535@1|root,COG0535@2|Bacteria,1MXM1@1224|Proteobacteria,1RNQ1@1236|Gammaproteobacteria,1X9IK@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_14,Radical_SAM
MMD2_k127_3323841_14	1122603.ATVI01000011_gene2110	2.819e-65	228.0	COG1443@1|root,COG1443@2|Bacteria,1R9YJ@1224|Proteobacteria,1S6ZT@1236|Gammaproteobacteria,1X6I1@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
MMD2_k127_3323841_2	1122604.JONR01000001_gene1872	4.487e-319	994.0	COG1257@1|root,COG1577@1|root,COG1257@2|Bacteria,COG1577@2|Bacteria,1MXVE@1224|Proteobacteria,1RS9R@1236|Gammaproteobacteria,1X8RF@135614|Xanthomonadales	135614|Xanthomonadales	I	Hydroxymethylglutaryl-coenzyme A reductase	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,HMG-CoA_red
MMD2_k127_3323841_17	666685.R2APBS1_3946	4.104e-46	179.0	COG1577@1|root,COG1577@2|Bacteria,1N400@1224|Proteobacteria,1SC29@1236|Gammaproteobacteria,1XAB2@135614|Xanthomonadales	135614|Xanthomonadales	I	GHMP kinases N terminal domain	-	-	2.7.4.2	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R03245	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
MMD2_k127_3323841_8	1122604.JONR01000001_gene1870	4.055e-113	376.0	COG3407@1|root,COG3407@2|Bacteria,1N5EZ@1224|Proteobacteria,1S19T@1236|Gammaproteobacteria,1X9HF@135614|Xanthomonadales	135614|Xanthomonadales	I	GHMP kinases N terminal domain	-	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
MMD2_k127_3323841_6	314278.NB231_00235	1.15e-118	392.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X0BB@135613|Chromatiales	135613|Chromatiales	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
MMD2_k127_3323841_21	472759.Nhal_1308	5.054e-18	94.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1WZQ1@135613|Chromatiales	135613|Chromatiales	F	other phosphorylase family 1	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMD2_k127_3323841_7	105559.Nwat_1203	3.222e-116	386.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,1RS93@1236|Gammaproteobacteria,1X0KC@135613|Chromatiales	135613|Chromatiales	I	Squalene phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
MMD2_k127_3323841_12	243233.MCA0818	2.232e-81	282.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XDRY@135618|Methylococcales	135618|Methylococcales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMD2_k127_3323841_15	1122604.JONR01000001_gene1847	1.152e-59	211.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S2N9@1236|Gammaproteobacteria,1X6DC@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
MMD2_k127_3323841_11	316067.Geob_2302	7.067e-93	319.0	COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria,42Z3E@68525|delta/epsilon subdivisions,2WU93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
MMD2_k127_3323841_1	765914.ThisiDRAFT_1157	0.0	1034.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW0R@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
MMD2_k127_3323841_13	396588.Tgr7_0703	1.298e-65	237.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1WWA8@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
MMD2_k127_3323841_9	861299.J421_5987	1.581e-106	352.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria	2|Bacteria	L	DNA ligase (ATP) activity	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
MMD2_k127_3427375_24	1323663.AROI01000016_gene488	7.718e-28	123.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA	hda	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
MMD2_k127_3427375_23	472759.Nhal_0875	1.233e-38	152.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,1WY27@135613|Chromatiales	135613|Chromatiales	I	PFAM CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMD2_k127_3427375_25	550540.Fbal_1257	2.987e-26	126.0	COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	VV2512	-	-	ko:K09938	-	-	-	-	ko00000	-	-	-	DUF2066
MMD2_k127_3427375_7	269482.Bcep1808_0721	1.774e-127	417.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1K2VU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMD2_k127_3427375_16	870187.Thini_0531	4.145e-65	244.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,460KB@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
MMD2_k127_3427375_26	1469245.JFBG01000075_gene158	3.998e-14	81.0	COG3170@1|root,COG3170@2|Bacteria,1R0PU@1224|Proteobacteria	1224|Proteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
MMD2_k127_3427375_13	391615.ABSJ01000022_gene280	6.184e-100	347.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,1J5D8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO1525	DCD,dUTPase
MMD2_k127_3427375_8	1123261.AXDW01000007_gene2145	1.634e-123	407.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1X4VI@135614|Xanthomonadales	135614|Xanthomonadales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
MMD2_k127_3427375_2	713586.KB900536_gene2577	1.788e-218	705.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1WX6D@135613|Chromatiales	135613|Chromatiales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
MMD2_k127_3427375_4	713586.KB900536_gene2578	6.68e-165	525.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
MMD2_k127_3427375_6	519989.ECTPHS_06817	4.873e-130	424.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMD2_k127_3427375_1	472759.Nhal_2751	1.138e-254	810.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1WWU6@135613|Chromatiales	135613|Chromatiales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
MMD2_k127_3427375_18	314285.KT71_19263	2.235e-58	208.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J832@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
MMD2_k127_3427375_9	768671.ThimaDRAFT_0934	1.828e-116	393.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
MMD2_k127_3427375_10	396588.Tgr7_2629	2.077e-113	376.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
MMD2_k127_3427375_21	323261.Noc_1171	9.351e-43	164.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WVYN@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
MMD2_k127_3427375_19	395493.BegalDRAFT_1826	3.094e-51	190.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,45ZVS@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
MMD2_k127_3427375_14	1415780.JPOG01000001_gene1976	1.075e-95	327.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1X340@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
MMD2_k127_3427375_27	1318628.MARLIPOL_15944	1.145e-12	74.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,1SZ3G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMD2_k127_3427375_22	1082933.MEA186_05551	3.238e-39	156.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
MMD2_k127_3427375_3	1122218.KB893653_gene1376	2.659e-218	709.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,1JTBI@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
MMD2_k127_3427375_5	1502852.FG94_03698	6.129e-153	512.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,4733P@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	1.8.1.4,2.3.1.12	ko:K00382,ko:K00627	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R02569,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMD2_k127_3427375_0	1260251.SPISAL_00215	0.0	1257.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
MMD2_k127_3427375_11	1123228.AUIH01000038_gene2751	9.422e-110	375.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1XH34@135619|Oceanospirillales	1236|Gammaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M17
MMD2_k127_3427375_15	1033802.SSPSH_001221	2.911e-80	274.0	COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis	rnt	GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K03683	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_T
MMD2_k127_3427375_20	686340.Metal_1492	5.63e-43	160.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1XFF2@135618|Methylococcales	135618|Methylococcales	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
MMD2_k127_3427375_17	1469245.JFBG01000039_gene1774	7.702e-62	218.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1X0P1@135613|Chromatiales	135613|Chromatiales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
MMD2_k127_3427375_12	1123401.JHYQ01000013_gene716	5.823e-101	338.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,45ZNU@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
MMD2_k127_3473376_40	298654.FraEuI1c_3545	1.818e-05	50.0	COG0111@1|root,COG0111@2|Bacteria,2GKTT@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA4	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMD2_k127_3473376_35	1187851.A33M_1047	5.418e-31	128.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMD2_k127_3473376_20	402881.Plav_0822	3.192e-85	293.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2TTFG@28211|Alphaproteobacteria,1JP6D@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD2_k127_3473376_10	1205680.CAKO01000002_gene2536	3.487e-112	377.0	COG0596@1|root,COG0596@2|Bacteria,1NDHC@1224|Proteobacteria,2UPRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMD2_k127_3473376_29	765869.BDW_13440	4.65e-63	231.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,42QRG@68525|delta/epsilon subdivisions,2WJ5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
MMD2_k127_3473376_21	316056.RPC_0743	3.548e-85	300.0	COG2220@1|root,COG2220@2|Bacteria,1MVP2@1224|Proteobacteria,2U2W2@28211|Alphaproteobacteria,3JUDF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
MMD2_k127_3473376_1	1415780.JPOG01000001_gene1992	0.0	1015.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1X34U@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMD2_k127_3473376_33	187272.Mlg_2696	4.251e-36	140.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1WYU9@135613|Chromatiales	135613|Chromatiales	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
MMD2_k127_3473376_7	396588.Tgr7_2945	2.985e-131	428.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1WW1U@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM A G-specific adenine glycosylase	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX_4
MMD2_k127_3473376_16	105559.Nwat_2097	2.435e-91	327.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1WXRZ@135613|Chromatiales	135613|Chromatiales	M	PFAM AsmA family protein	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
MMD2_k127_3473376_19	1120983.KB894575_gene528	4.432e-86	299.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,1JPNG@119043|Rhodobiaceae	28211|Alphaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Response_reg,sCache_2
MMD2_k127_3473376_15	765910.MARPU_06270	9.206e-94	322.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1T2H7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
MMD2_k127_3473376_25	713587.THITH_01190	4.816e-75	259.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1WY2P@135613|Chromatiales	135613|Chromatiales	J	catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
MMD2_k127_3473376_3	1522072.IL54_1262	1.52e-179	572.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2TTD2@28211|Alphaproteobacteria,2K1E8@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
MMD2_k127_3473376_14	396588.Tgr7_0109	2.59e-95	330.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Exodeoxyribonuclease III	crc	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
MMD2_k127_3473376_23	717774.Marme_0505	3.084e-77	277.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XHYH@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
MMD2_k127_3473376_36	396588.Tgr7_0105	1.955e-20	100.0	COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1S7FF@1236|Gammaproteobacteria,1WYCM@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
MMD2_k127_3473376_28	1122603.ATVI01000006_gene121	1.027e-69	240.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,1X61M@135614|Xanthomonadales	135614|Xanthomonadales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
MMD2_k127_3473376_6	314278.NB231_11229	1.041e-140	458.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
MMD2_k127_3473376_27	1177179.A11A3_09080	9.126e-72	253.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1XI72@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
MMD2_k127_3473376_34	1354303.M917_0409	4.233e-34	132.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,3NNZ1@468|Moraxellaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
MMD2_k127_3473376_37	393595.ABO_0216	1.688e-19	88.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1XMCR@135619|Oceanospirillales	135619|Oceanospirillales	J	there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
MMD2_k127_3473376_8	314278.NB231_13841	4.032e-118	392.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RSN1@1236|Gammaproteobacteria,1WVUQ@135613|Chromatiales	135613|Chromatiales	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
MMD2_k127_3473376_13	1265313.HRUBRA_01216	1.235e-97	325.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1J5A0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
MMD2_k127_3473376_5	1173027.Mic7113_4587	4.195e-157	522.0	COG0405@1|root,COG0405@2|Bacteria,1G14N@1117|Cyanobacteria,1H83V@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMD2_k127_3473376_30	292415.Tbd_0380	8.566e-62	221.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,1KRNG@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMD2_k127_3473376_32	203122.Sde_3598	3.9e-41	159.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,467AQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	rsmD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
MMD2_k127_3473376_12	713586.KB900536_gene1798	6.083e-100	334.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1WW5G@135613|Chromatiales	135613|Chromatiales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
MMD2_k127_3473376_22	1286106.MPL1_06999	1.128e-82	293.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,4604Q@72273|Thiotrichales	72273|Thiotrichales	D	TIGRFAM Cell division ATP-binding protein FtsE	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
MMD2_k127_3473376_26	349521.HCH_00574	4.52e-72	253.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1XHHT@135619|Oceanospirillales	135619|Oceanospirillales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
MMD2_k127_3473376_11	519989.ECTPHS_06597	2.717e-111	366.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1WWRE@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
MMD2_k127_3473376_24	187272.Mlg_0328	3.215e-77	264.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1WWRS@135613|Chromatiales	135613|Chromatiales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
MMD2_k127_3473376_18	1042377.AFPJ01000029_gene551	2.791e-88	297.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,465DT@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	chvI	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K02483,ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_3473376_0	314230.DSM3645_15695	0.0	2235.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2IXKD@203682|Planctomycetes	203682|Planctomycetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
MMD2_k127_3473376_2	530564.Psta_0200	1.017e-240	751.0	COG0493@1|root,COG0493@2|Bacteria,2IXFM@203682|Planctomycetes	203682|Planctomycetes	C	COG0493 NADPH-dependent glutamate synthase beta chain and	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
MMD2_k127_3473376_17	321327.CYA_0467	8.072e-91	304.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1GYT4@1129|Synechococcus	1117|Cyanobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
MMD2_k127_3473376_31	1437425.CSEC_1842	5.113e-57	209.0	COG0121@1|root,COG0121@2|Bacteria,2JG9A@204428|Chlamydiae	204428|Chlamydiae	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
MMD2_k127_3473376_9	1121937.AUHJ01000003_gene3229	1.783e-116	400.0	COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,1T311@1236|Gammaproteobacteria,46D2F@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,HATPase_c,HisKA
MMD2_k127_3473376_38	292415.Tbd_0149	6.148e-09	63.0	COG5608@1|root,COG5608@2|Bacteria	2|Bacteria	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
MMD2_k127_3473376_4	1304275.C41B8_10043	2.064e-168	542.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed	fadI	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMD2_k127_349699_4	349124.Hhal_0860	1.883e-17	82.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1WWIK@135613|Chromatiales	135613|Chromatiales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMD2_k127_349699_0	472759.Nhal_2382	1.199e-289	904.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1WW0N@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMD2_k127_349699_3	1049564.TevJSym_bu00020	3.26e-61	220.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1J5QN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
MMD2_k127_349699_2	105559.Nwat_2163	2.513e-63	218.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,1WYAY@135613|Chromatiales	135613|Chromatiales	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
MMD2_k127_349699_1	90813.JQMT01000001_gene208	1.435e-185	592.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMD2_k127_3592477_20	314285.KT71_04940	6.023e-11	67.0	2EITU@1|root,33CJ4@2|Bacteria,1NMF7@1224|Proteobacteria,1SI8Z@1236|Gammaproteobacteria,1JARU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3592477_6	243231.GSU0946	3.448e-130	444.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43SWK@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	sensor diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0700	EAL,GGDEF,HAMP,PAS_4,PAS_9
MMD2_k127_3592477_10	96561.Dole_0172	8.164e-96	328.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42S0M@68525|delta/epsilon subdivisions,2WNYE@28221|Deltaproteobacteria,2MMEA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
MMD2_k127_3592477_22	349741.Amuc_1454	0.0001752	49.0	COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia,2IUPK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMD2_k127_3592477_18	1232410.KI421412_gene22	8.522e-15	78.0	2EKQ7@1|root,33EDZ@2|Bacteria,1NHK0@1224|Proteobacteria,42WYF@68525|delta/epsilon subdivisions,2WSKJ@28221|Deltaproteobacteria,43VUS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2845
MMD2_k127_3592477_3	472759.Nhal_3173	1.17e-150	493.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1WWFZ@135613|Chromatiales	135613|Chromatiales	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
MMD2_k127_3592477_5	296591.Bpro_5300	1.467e-130	428.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2VJSV@28216|Betaproteobacteria,4AAZZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AIF_C,Pyr_redox_2,Reductase_C
MMD2_k127_3592477_7	404589.Anae109_2985	2.946e-123	404.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2YWUY@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
MMD2_k127_3592477_15	472759.Nhal_0366	5.928e-39	153.0	2DKHM@1|root,309GY@2|Bacteria,1RFJ6@1224|Proteobacteria,1S4EG@1236|Gammaproteobacteria,1X1R5@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3592477_14	105559.Nwat_3039	5.412e-40	156.0	2AI7D@1|root,33HQ0@2|Bacteria,1P2AB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3592477_4	1469245.JFBG01000057_gene2370	2.79e-136	447.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1WWU0@135613|Chromatiales	135613|Chromatiales	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMD2_k127_3592477_11	251229.Chro_4898	2.883e-82	289.0	COG0604@1|root,COG0604@2|Bacteria,1G241@1117|Cyanobacteria,3VMDF@52604|Pleurocapsales	1117|Cyanobacteria	C	COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_3592477_0	765911.Thivi_3675	3.244e-210	664.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
MMD2_k127_3592477_21	580332.Slit_2306	1.271e-10	67.0	2DRTJ@1|root,33CZM@2|Bacteria,1QF7V@1224|Proteobacteria,2VXR2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
MMD2_k127_3592477_17	1101190.ARWB01000001_gene1542	1.019e-23	110.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2TURT@28211|Alphaproteobacteria,36X6H@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
MMD2_k127_3592477_13	1158760.AQXP01000042_gene2331	9.854e-50	181.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1WYBE@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
MMD2_k127_3592477_12	1095769.CAHF01000013_gene3262	1.613e-59	213.0	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,2VQ9D@28216|Betaproteobacteria,47414@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1415)	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
MMD2_k127_3592477_16	1207063.P24_15831	3.549e-30	138.0	2DM5E@1|root,31SVN@2|Bacteria,1MYKR@1224|Proteobacteria,2U9KT@28211|Alphaproteobacteria,2JSXH@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
MMD2_k127_3592477_1	1001585.MDS_3349	4.725e-161	527.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,1YFFN@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
MMD2_k127_3592477_9	1123073.KB899242_gene1477	1.267e-103	347.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMD2_k127_3592477_8	1123073.KB899242_gene1478	7.222e-116	381.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1X3JY@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_3592477_2	518766.Rmar_0089	3.072e-153	495.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMD2_k127_35970_2	1397527.Q670_13740	1.473e-259	816.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XH4B@135619|Oceanospirillales	135619|Oceanospirillales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
MMD2_k127_35970_16	1415780.JPOG01000001_gene1981	2.455e-76	263.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,1X67H@135614|Xanthomonadales	135614|Xanthomonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMD2_k127_35970_32	314278.NB231_12576	2.267e-39	150.0	COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1WZ3B@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF1820)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1820
MMD2_k127_35970_29	1122194.AUHU01000003_gene2294	5.606e-45	181.0	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1T0B8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	conserved protein, contains FHA domain	-	-	-	ko:K11894,ko:K11913	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko02044	3.A.23.1	-	-	FHA
MMD2_k127_35970_23	595460.RRSWK_04882	3.439e-56	208.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
MMD2_k127_35970_15	756272.Plabr_2883	2.056e-89	312.0	COG0515@1|root,COG0515@2|Bacteria,2J2D5@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMD2_k127_35970_10	1120956.JHZK01000023_gene1143	5.194e-116	382.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,1JNAG@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
MMD2_k127_35970_3	644968.DFW101_0023	8.121e-218	702.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MAGR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
MMD2_k127_35970_36	375286.mma_2598	3.512e-33	137.0	COG3126@1|root,COG3895@1|root,COG3126@2|Bacteria,COG3895@2|Bacteria,1N8AF@1224|Proteobacteria,2VXB0@28216|Betaproteobacteria,476TJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	MliC,YscW
MMD2_k127_35970_4	59538.XP_005973739.1	7.026e-158	511.0	COG0624@1|root,KOG2275@2759|Eukaryota,39RWD@33154|Opisthokonta,3BEKC@33208|Metazoa,3CSZJ@33213|Bilateria,4818N@7711|Chordata,493PC@7742|Vertebrata,3J52B@40674|Mammalia,4IYI2@91561|Cetartiodactyla	33208|Metazoa	E	Carboxypeptidase	-	-	3.5.1.14	ko:K14677	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00669,R10553	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMD2_k127_35970_42	1177179.A11A3_14827	1.009e-07	62.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,1SZWA@1236|Gammaproteobacteria,1XQVW@135619|Oceanospirillales	135619|Oceanospirillales	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMD2_k127_35970_5	1316936.K678_15556	3.849e-142	465.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,2JPKJ@204441|Rhodospirillales	204441|Rhodospirillales	C	COG0277 FAD FMN-containing dehydrogenases	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMD2_k127_35970_40	2074.JNYD01000007_gene2076	2.33e-11	76.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4E8J0@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_35970_1	452637.Oter_1368	2.406e-270	858.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_35970_34	1535422.ND16A_0698	1.347e-34	140.0	COG0457@1|root,COG0457@2|Bacteria,1RESK@1224|Proteobacteria,1S41N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_8
MMD2_k127_35970_13	1122137.AQXF01000001_gene2558	7.984e-98	325.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2TSR6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the pirin family	MA20_06040	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
MMD2_k127_35970_27	864051.BurJ1DRAFT_1894	1.742e-48	178.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
MMD2_k127_35970_24	296591.Bpro_3704	5.051e-54	192.0	2DQ60@1|root,334WQ@2|Bacteria,1NADI@1224|Proteobacteria,2VUFT@28216|Betaproteobacteria,4AFA4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
MMD2_k127_35970_9	35754.JNYJ01000040_gene1504	3.296e-122	404.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4D9FK@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMD2_k127_35970_22	1313172.YM304_42520	4.211e-57	223.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
MMD2_k127_35970_7	1385517.N800_08795	2.423e-136	447.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,1RYUQ@1236|Gammaproteobacteria,1X5KG@135614|Xanthomonadales	135614|Xanthomonadales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_35970_18	913325.N799_13100	8.323e-69	243.0	COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1RQ3M@1236|Gammaproteobacteria,1X6AP@135614|Xanthomonadales	135614|Xanthomonadales	P	Co Zn Cd efflux system component	czcD1	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
MMD2_k127_35970_31	1267533.KB906741_gene406	2.483e-40	158.0	2B4PH@1|root,31XFS@2|Bacteria,3Y8X7@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
MMD2_k127_35970_37	1230476.C207_02620	2.255e-31	126.0	COG2010@1|root,COG2010@2|Bacteria,1NK3D@1224|Proteobacteria,2UN55@28211|Alphaproteobacteria,3K3Y7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMD2_k127_35970_0	1230476.C207_02619	4.37e-283	889.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,3JX83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMD2_k127_35970_38	882082.SaccyDRAFT_5082	9.078e-25	107.0	COG3801@1|root,COG3801@2|Bacteria,2HRAA@201174|Actinobacteria,4E53W@85010|Pseudonocardiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
MMD2_k127_35970_25	329726.AM1_5487	8.554e-52	188.0	COG0346@1|root,COG0346@2|Bacteria,1GGSQ@1117|Cyanobacteria	1117|Cyanobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_35970_11	1521187.JPIM01000098_gene3786	2.402e-113	385.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,375DB@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMD2_k127_35970_14	1235457.C404_26515	3.793e-95	320.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria,1K5U4@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD2_k127_35970_19	379066.GAU_1374	1.331e-68	243.0	28NKC@1|root,2ZBM7@2|Bacteria,1ZUHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_35970_20	1336208.JADY01000020_gene3414	1.31e-60	228.0	COG0235@1|root,COG0235@2|Bacteria,1RB5Z@1224|Proteobacteria,2U0PK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Class II aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
MMD2_k127_35970_8	1123023.JIAI01000001_gene6612	3.443e-127	429.0	COG1960@1|root,COG1960@2|Bacteria,2IAYB@201174|Actinobacteria,4E0DQ@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
MMD2_k127_35970_17	1242864.D187_000771	4.944e-72	248.0	COG0625@1|root,COG0625@2|Bacteria,1RA05@1224|Proteobacteria,4380E@68525|delta/epsilon subdivisions,2X3AG@28221|Deltaproteobacteria,2YV4P@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N
MMD2_k127_35970_6	1320556.AVBP01000007_gene615	1.838e-139	454.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMD2_k127_35970_35	765911.Thivi_2512	1.443e-34	144.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1WX3V@135613|Chromatiales	135613|Chromatiales	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
MMD2_k127_35970_28	879212.DespoDRAFT_01673	2.899e-48	176.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42VJU@68525|delta/epsilon subdivisions,2WRA4@28221|Deltaproteobacteria,2MP0R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
MMD2_k127_35970_30	1247726.MIM_c02580	1.574e-40	158.0	COG3556@1|root,COG3556@2|Bacteria,1N3XH@1224|Proteobacteria,2VRQ4@28216|Betaproteobacteria,3T4VJ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2214)	-	-	-	ko:K08983	-	-	-	-	ko00000	-	-	-	DUF2214
MMD2_k127_35970_21	1114970.PSF113_2577	9.251e-60	223.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_7
MMD2_k127_35970_33	1279017.AQYJ01000028_gene2525	2.844e-39	167.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_35970_12	1500894.JQNN01000001_gene4007	6.885e-98	327.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,4794W@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_3645920_3	1286106.MPL1_01856	4.617e-156	510.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,45ZSG@72273|Thiotrichales	72273|Thiotrichales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
MMD2_k127_3645920_0	1304275.C41B8_01340	4.12e-243	766.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMD2_k127_3645920_4	627192.SLG_27600	1.705e-146	477.0	COG2271@1|root,COG2271@2|Bacteria,1P24P@1224|Proteobacteria,2URTW@28211|Alphaproteobacteria,2KCKR@204457|Sphingomonadales	204457|Sphingomonadales	G	Sugar (and other) transporter	-	-	-	ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1
MMD2_k127_3645920_17	1028800.RG540_PA00200	3.129e-21	97.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,4BBRG@82115|Rhizobiaceae	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMD2_k127_3645920_5	935840.JAEQ01000020_gene2336	6.034e-138	452.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMD2_k127_3645920_20	1056820.KB900634_gene1940	9.608e-16	83.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,2PNRB@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Protein of unknown function (DUF423)	ygdD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF423
MMD2_k127_3645920_15	1042326.AZNV01000003_gene3944	2.127e-42	164.0	COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,2U57Q@28211|Alphaproteobacteria,4B899@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
MMD2_k127_3645920_14	1333856.L686_08995	1.676e-46	175.0	COG5608@1|root,COG5608@2|Bacteria,1N15F@1224|Proteobacteria,1SC93@1236|Gammaproteobacteria,1Z4G9@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Water Stress and Hypersensitive response	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
MMD2_k127_3645920_7	471852.Tcur_3455	9.555e-120	395.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4EI19@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
MMD2_k127_3645920_1	1085623.GNIT_2631	6.357e-213	693.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_3645920_12	1121015.N789_12060	1.59e-77	262.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,1X610@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the glutathione peroxidase family	gpo	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
MMD2_k127_3645920_2	861299.J421_2420	4.338e-180	583.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
MMD2_k127_3645920_21	861299.J421_2419	5.904e-06	56.0	2C4I0@1|root,32SKD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD2_k127_3645920_8	861299.J421_2418	7.86e-119	400.0	COG2303@1|root,COG2303@2|Bacteria,1ZUUJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C
MMD2_k127_3645920_18	216591.BCAL2634a	1.574e-17	89.0	COG5430@1|root,COG5430@2|Bacteria,1N6IV@1224|Proteobacteria,2WG63@28216|Betaproteobacteria,1KG24@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Spore Coat Protein U domain	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
MMD2_k127_3645920_19	1424334.W822_04150	1.015e-16	89.0	COG3121@1|root,COG3121@2|Bacteria,1R4RJ@1224|Proteobacteria,2WAQZ@28216|Betaproteobacteria,3T4VR@506|Alcaligenaceae	28216|Betaproteobacteria	NU	COG3121 P pilus assembly protein, chaperone PapD	-	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
MMD2_k127_3645920_10	1163408.UU9_16341	7.412e-107	377.0	COG0860@1|root,COG3188@1|root,COG0860@2|Bacteria,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,1RNWK@1236|Gammaproteobacteria,1X3RZ@135614|Xanthomonadales	135614|Xanthomonadales	NU	outer membrane usher protein	fasD	-	-	ko:K07347	ko05133,map05133	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.B.11.3	-	-	PapC_C,Usher
MMD2_k127_3645920_16	452662.SJA_C1-07070	1.615e-21	107.0	COG5430@1|root,COG5430@2|Bacteria,1N5AX@1224|Proteobacteria,2UD10@28211|Alphaproteobacteria,2K70Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Spore Coat Protein U domain	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
MMD2_k127_3645920_9	1040983.AXAE01000023_gene3	5.863e-112	379.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2U2ES@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
MMD2_k127_3645920_6	1267005.KB911255_gene2483	8.607e-133	444.0	COG4591@1|root,COG4591@2|Bacteria,1Q2BY@1224|Proteobacteria,2TVP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
MMD2_k127_3645920_11	316055.RPE_3952	1.341e-99	330.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,3JWVM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD1	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
MMD2_k127_3645920_13	666685.R2APBS1_0174	1.901e-55	203.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1X46E@135614|Xanthomonadales	135614|Xanthomonadales	L	Helicase	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMD2_k127_3699029_0	190650.CC_2105	9.766e-139	463.0	COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,2U2RD@28211|Alphaproteobacteria,2KFJC@204458|Caulobacterales	204458|Caulobacterales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMD2_k127_3706961_9	861299.J421_4151	3.022e-95	325.0	COG3182@1|root,COG3182@2|Bacteria,1ZUQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
MMD2_k127_3706961_18	1209072.ALBT01000033_gene1619	7.464e-10	67.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,1FH9W@10|Cellvibrio	1236|Gammaproteobacteria	S	Glycine zipper 2TM domain	ycfJ	GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
MMD2_k127_3706961_10	1207076.ALAT01000036_gene4218	2.288e-44	167.0	COG0727@1|root,COG0727@2|Bacteria,1N027@1224|Proteobacteria,1S949@1236|Gammaproteobacteria,1Z2QP@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Fe-S-cluster oxidoreductase	ykgJ	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
MMD2_k127_3706961_0	113395.AXAI01000053_gene2640	7.003e-308	988.0	COG0507@1|root,COG1112@1|root,COG2251@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,3JQNN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
MMD2_k127_3706961_11	713586.KB900536_gene1532	3.3e-39	153.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1X2HD@135613|Chromatiales	135613|Chromatiales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
MMD2_k127_3706961_17	589873.EP13_13630	5.943e-14	83.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3706961_6	243233.MCA1608	5.302e-106	362.0	COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,1T3FR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
MMD2_k127_3706961_8	314285.KT71_02512	3.596e-105	355.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1J8R1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
MMD2_k127_3706961_21	477641.MODMU_5086	0.000417	49.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMD2_k127_3706961_13	1210045.ALNP01000033_gene2509	9.219e-25	115.0	COG2085@1|root,COG2085@2|Bacteria,2I8W4@201174|Actinobacteria	201174|Actinobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
MMD2_k127_3706961_15	1158762.KB898039_gene1641	2.503e-19	103.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,1SE9G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4
MMD2_k127_3706961_7	886293.Sinac_1154	1.1e-105	359.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_3706961_1	234267.Acid_5827	3.999e-215	696.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_3706961_12	234267.Acid_5517	2.985e-32	132.0	COG0657@1|root,COG0657@2|Bacteria,3Y44Z@57723|Acidobacteria	57723|Acidobacteria	I	Alpha beta hydrolase fold-3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMD2_k127_3706961_5	1298867.AUES01000002_gene1481	3.958e-116	385.0	COG3391@1|root,COG3391@2|Bacteria,1MXRF@1224|Proteobacteria,2U1E9@28211|Alphaproteobacteria,3JTTY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD2_k127_3706961_2	1037409.BJ6T_40350	9.818e-213	679.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3JUB5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
MMD2_k127_3706961_3	509635.N824_10830	1.011e-177	572.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,1IQQB@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
MMD2_k127_3706961_14	1266909.AUAG01000025_gene1846	7.624e-20	96.0	COG2405@1|root,COG2405@2|Bacteria,1PVSE@1224|Proteobacteria,1SVJK@1236|Gammaproteobacteria,1X1K9@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
MMD2_k127_3706961_16	1184267.A11Q_1141	1.257e-18	90.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria	1224|Proteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMD2_k127_3706961_19	3694.POPTR_0009s07030.1	1.039e-09	63.0	KOG0118@1|root,KOG0118@2759|Eukaryota,37MFE@33090|Viridiplantae,3GCQV@35493|Streptophyta,4JMNX@91835|fabids	35493|Streptophyta	A	30S ribosomal protein 2	-	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009651,GO:0009941,GO:0010029,GO:0010035,GO:0016020,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042221,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0047484,GO:0048519,GO:0048580,GO:0048583,GO:0048585,GO:0050789,GO:0050793,GO:0050896,GO:0051239,GO:0055035,GO:0065007,GO:0080134,GO:0080148,GO:0097159,GO:1900140,GO:1901000,GO:1901001,GO:1901363,GO:1901700,GO:2000026,GO:2000070	-	ko:K13126	ko03013,ko03015,ko03018,map03013,map03015,map03018	-	-	-	ko00000,ko00001,ko03019,ko03041	-	-	-	RRM_1
MMD2_k127_3706961_20	1380390.JIAT01000001_gene5102	1.286e-05	55.0	COG2128@1|root,COG2128@2|Bacteria,2IB85@201174|Actinobacteria,4CSN3@84995|Rubrobacteria	84995|Rubrobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMD2_k127_3733395_2	396588.Tgr7_0483	7.871e-85	303.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1WVXZ@135613|Chromatiales	135613|Chromatiales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
MMD2_k127_3733395_4	264198.Reut_A0750	1.55e-27	115.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria,1K7NH@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM Rhodanese domain protein	pspE2	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMD2_k127_3733395_3	396588.Tgr7_0485	7.036e-58	211.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1WX4D@135613|Chromatiales	135613|Chromatiales	O	PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
MMD2_k127_3733395_0	1123368.AUIS01000023_gene933	6.192e-164	546.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_4
MMD2_k127_3733395_1	391615.ABSJ01000026_gene133	1.803e-120	411.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J4C2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
MMD2_k127_3775884_7	136993.KB900627_gene392	4.096e-26	117.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3775884_8	247633.GP2143_17801	2.559e-22	101.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3775884_5	627192.SLG_09880	1.235e-28	126.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3775884_6	639030.JHVA01000001_gene1885	2.343e-26	113.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3775884_2	1238450.VIBNISOn1_30232	4.899e-63	228.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1XWW1@135623|Vibrionales	135623|Vibrionales	O	SelR domain	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
MMD2_k127_3775884_1	1532558.JL39_07180	5.567e-91	305.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,4B9SN@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
MMD2_k127_3775884_0	1122604.JONR01000007_gene2812	0.0	1185.0	COG0841@1|root,COG0841@2|Bacteria,1QXYC@1224|Proteobacteria,1T3KA@1236|Gammaproteobacteria,1XDE0@135614|Xanthomonadales	135614|Xanthomonadales	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
MMD2_k127_3775884_3	1163617.SCD_n02730	4.8e-61	219.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0502 family	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
MMD2_k127_3775884_4	861299.J421_1876	2.997e-53	204.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
MMD2_k127_3775884_9	566466.NOR53_2998	3.2e-06	51.0	2919Q@1|root,32TZW@2|Bacteria,1Q71M@1224|Proteobacteria,1SIND@1236|Gammaproteobacteria,1J87S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3865509_5	1122137.AQXF01000002_gene562	4.887e-27	113.0	COG3658@1|root,COG3658@2|Bacteria	2|Bacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	DHC,Ni_hydr_CYTB
MMD2_k127_3865509_1	1123242.JH636434_gene5626	5.219e-64	231.0	COG4886@1|root,COG5426@1|root,COG4886@2|Bacteria,COG5426@2|Bacteria	2|Bacteria	D	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,Flg_new,LRR_5,LRR_6
MMD2_k127_3865509_0	136993.KB900627_gene392	5.372e-66	245.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3865509_4	1335760.ASTG01000003_gene1751	1.108e-27	129.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3865509_3	136993.KB900627_gene391	6.577e-30	123.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3865509_2	1144305.PMI02_01782	2.089e-53	198.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,2TVDN@28211|Alphaproteobacteria,2K2S7@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_3874877_13	1265313.HRUBRA_01524	5.914e-09	67.0	2C612@1|root,32RGH@2|Bacteria,1RGYZ@1224|Proteobacteria,1S8MM@1236|Gammaproteobacteria,1J6RN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3874877_6	1385515.N791_01060	4.429e-122	404.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria,1X3K1@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA repair photolyase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMD2_k127_3874877_10	318161.Sden_3461	6.567e-67	236.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,2Q9KR@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Two component transcriptional regulator, winged helix family	cpxR	GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010810,GO:0019219,GO:0019222,GO:0030155,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07662,ko:K19610	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728,M00770	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_3874877_8	323261.Noc_0675	1.213e-69	253.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1T1JX@1236|Gammaproteobacteria,1X2Q8@135613|Chromatiales	135613|Chromatiales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMD2_k127_3874877_1	765912.Thimo_1930	2.178e-175	561.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWT4@135613|Chromatiales	135613|Chromatiales	U	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMD2_k127_3874877_12	225937.HP15_275	1.133e-52	187.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,467D0@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
MMD2_k127_3874877_5	1121013.P873_02290	4.513e-127	415.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,1X3VH@135614|Xanthomonadales	135614|Xanthomonadales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
MMD2_k127_3874877_11	1249627.D779_2556	4.115e-56	202.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1WYDE@135613|Chromatiales	135613|Chromatiales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
MMD2_k127_3874877_14	1122604.JONR01000021_gene618	2.289e-05	54.0	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1X7KU@135614|Xanthomonadales	135614|Xanthomonadales	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
MMD2_k127_3874877_7	323261.Noc_2682	5.977e-74	275.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9
MMD2_k127_3874877_4	261292.Nit79A3_0718	3.953e-133	445.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2WGNM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K06714,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	HTH_8,PAS_4,Sigma54_activat
MMD2_k127_3874877_9	111780.Sta7437_3987	1.804e-68	259.0	COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,3VHRB@52604|Pleurocapsales	1117|Cyanobacteria	Q	Phospholipase/Carboxylesterase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMD2_k127_3874877_2	2340.JV46_14610	6.746e-164	526.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
MMD2_k127_3874877_3	1265313.HRUBRA_00272	2.469e-143	460.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1J5A8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
MMD2_k127_3874877_0	518766.Rmar_0089	8.108e-245	772.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMD2_k127_3923483_22	247634.GPB2148_2608	4.352e-44	167.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria	1224|Proteobacteria	L	Hydrolase	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMD2_k127_3923483_4	518766.Rmar_2567	1.189e-169	557.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
MMD2_k127_3923483_32	1042375.AFPL01000019_gene231	3.692e-08	57.0	COG1918@1|root,COG1918@2|Bacteria,1Q29C@1224|Proteobacteria,1TCA4@1236|Gammaproteobacteria,4694M@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
MMD2_k127_3923483_3	391615.ABSJ01000055_gene1354	2.181e-176	564.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1J4X6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889	Adenylsucc_synt
MMD2_k127_3923483_31	1415780.JPOG01000001_gene1809	2.181e-10	63.0	COG3242@1|root,COG3242@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	yjeT	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
MMD2_k127_3923483_17	582744.Msip34_1689	3.885e-85	293.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,2KM4X@206350|Nitrosomonadales	206350|Nitrosomonadales	O	HflC and HflK could regulate a protease	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
MMD2_k127_3923483_13	396588.Tgr7_0899	5.497e-100	338.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1WWWJ@135613|Chromatiales	135613|Chromatiales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
MMD2_k127_3923483_11	713587.THITH_13450	7.377e-135	442.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1WVYW@135613|Chromatiales	135613|Chromatiales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
MMD2_k127_3923483_24	1249627.D779_0209	1.501e-34	136.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1WYTY@135613|Chromatiales	135613|Chromatiales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
MMD2_k127_3923483_15	187272.Mlg_0572	5.029e-96	325.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1WWI0@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
MMD2_k127_3923483_2	713586.KB900536_gene2956	1.563e-197	632.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1WWKZ@135613|Chromatiales	135613|Chromatiales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
MMD2_k127_3923483_12	287.DR97_2300	2.064e-117	392.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1YD5A@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
MMD2_k127_3923483_27	768671.ThimaDRAFT_3776	2.455e-22	109.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1WYI3@135613|Chromatiales	135613|Chromatiales	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
MMD2_k127_3923483_10	314278.NB231_15443	1.214e-138	456.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1WW1V@135613|Chromatiales	135613|Chromatiales	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
MMD2_k127_3923483_7	472759.Nhal_3427	6.616e-148	486.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1WWZ4@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
MMD2_k127_3923483_16	1123261.AXDW01000002_gene1665	1.357e-95	322.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1X42V@135614|Xanthomonadales	135614|Xanthomonadales	H	polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
MMD2_k127_3923483_20	1226994.AMZB01000138_gene5797	2.618e-69	247.0	COG2199@1|root,COG3706@2|Bacteria,1REIE@1224|Proteobacteria,1SPFU@1236|Gammaproteobacteria,1YEC1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,cNMP_binding
MMD2_k127_3923483_18	870187.Thini_4282	2.806e-78	283.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,460GY@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
MMD2_k127_3923483_14	1415780.JPOG01000001_gene1836	4.748e-98	329.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1X3R8@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	-	-	-	-	-	-	-	-	-	-	-	-	Pantoate_transf
MMD2_k127_3923483_19	713586.KB900536_gene2943	2.306e-76	267.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,1X2ET@135613|Chromatiales	135613|Chromatiales	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
MMD2_k127_3923483_9	572477.Alvin_2758	4.078e-147	479.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1WWHC@135613|Chromatiales	135613|Chromatiales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
MMD2_k127_3923483_33	1197906.CAJQ02000046_gene3843	0.0006648	44.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
MMD2_k127_3923483_29	555793.WSK_2874	3.173e-17	86.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3923483_28	661367.LLO_1867	5.12e-19	90.0	COG2388@1|root,COG2608@1|root,COG2388@2|Bacteria,COG2608@2|Bacteria,1QW3C@1224|Proteobacteria,1T2R9@1236|Gammaproteobacteria,1JGQ2@118969|Legionellales	118969|Legionellales	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_3923483_5	622637.KE124774_gene286	2.958e-159	517.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,36XH9@31993|Methylocystaceae	28211|Alphaproteobacteria	L	DNA photolyase	phrB	GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
MMD2_k127_3923483_8	1122185.N792_06425	3.17e-147	482.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria,1X3GK@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16
MMD2_k127_3923483_1	722419.PH505_bc00130	2.842e-199	647.0	COG4773@1|root,COG4773@2|Bacteria,1QURT@1224|Proteobacteria,1SM3F@1236|Gammaproteobacteria,2PZVJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_3923483_25	472759.Nhal_3016	2.043e-31	129.0	COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1WYQZ@135613|Chromatiales	135613|Chromatiales	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMD2_k127_3923483_23	765914.ThisiDRAFT_2647	8.825e-44	182.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1WWXY@135613|Chromatiales	135613|Chromatiales	S	Permease YjgP YjgQ	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
MMD2_k127_3923483_21	349124.Hhal_0680	6.199e-64	239.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1WWGT@135613|Chromatiales	135613|Chromatiales	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
MMD2_k127_3923483_6	666681.M301_0276	1.811e-149	490.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,2KKR5@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
MMD2_k127_3923483_26	105559.Nwat_0389	2.162e-29	136.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1WYQ1@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III, chi subunit	-	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
MMD2_k127_3923483_0	519989.ECTPHS_04920	7.277e-263	821.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales	135613|Chromatiales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
MMD2_k127_395091_20	1101195.Meth11DRAFT_1464	1.134e-31	130.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_395091_19	136993.KB900627_gene392	4.219e-35	147.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_395091_13	136993.KB900627_gene392	2.674e-51	194.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_395091_9	1267533.KB906734_gene4311	4.501e-72	260.0	COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria,2JMEC@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD2_k127_395091_10	1248916.ANFY01000010_gene336	1.647e-71	261.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,2K7GT@204457|Sphingomonadales	204457|Sphingomonadales	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD2_k127_395091_6	234267.Acid_5491	2.999e-78	276.0	COG2333@1|root,COG2333@2|Bacteria,3Y323@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_395091_29	1101195.Meth11DRAFT_1464	2.059e-12	73.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_395091_15	107636.JQNK01000009_gene1854	4.594e-48	184.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_395091_32	589873.EP13_13630	8.934e-07	60.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_395091_0	861299.J421_0317	3.914e-225	719.0	28JZZ@1|root,2Z9PZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_395091_25	114615.BRADO3117	7.587e-20	105.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2U2S9@28211|Alphaproteobacteria,3JX6E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
MMD2_k127_395091_5	234267.Acid_5749	1.054e-91	329.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
MMD2_k127_395091_17	1395516.PMO01_19055	6.182e-43	162.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,1S3RV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD2_k127_395091_27	1502852.FG94_02922	1.47e-12	76.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2VR28@28216|Betaproteobacteria,475GE@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	carboxymuconolactone decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMD2_k127_395091_4	330084.JNYZ01000047_gene2941	3.739e-96	332.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMD2_k127_395091_12	487316.BBNM01000005_gene299	3.251e-53	203.0	COG0583@1|root,COG0583@2|Bacteria,1Q8UG@1224|Proteobacteria,1S05A@1236|Gammaproteobacteria,3NKV9@468|Moraxellaceae	1236|Gammaproteobacteria	K	LysR substrate binding domain	hcaR	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K05817	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
MMD2_k127_395091_1	287986.DV20_42940	7.289e-146	473.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4E0VY@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMD2_k127_395091_33	247490.KSU1_C0461	3.397e-06	60.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,2J22H@203682|Planctomycetes	203682|Planctomycetes	EI	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
MMD2_k127_395091_3	1522072.IL54_1965	3.615e-115	385.0	COG1775@1|root,COG1775@2|Bacteria,1R4FZ@1224|Proteobacteria,2U405@28211|Alphaproteobacteria,2K3JG@204457|Sphingomonadales	204457|Sphingomonadales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
MMD2_k127_395091_26	316055.RPE_2200	1.839e-13	84.0	COG2271@1|root,COG2271@2|Bacteria,1MUEK@1224|Proteobacteria,2TS60@28211|Alphaproteobacteria,3JWWC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K13021	-	-	-	-	ko00000,ko02000	2.A.1.14.3	-	-	MFS_1
MMD2_k127_395091_7	1254432.SCE1572_28410	1.066e-77	286.0	COG4099@1|root,COG4099@2|Bacteria	2|Bacteria	F	phospholipase Carboxylesterase	gbpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Abhydrolase_8,Peptidase_S9
MMD2_k127_395091_8	702113.PP1Y_Mpl283	6.072e-74	259.0	COG0657@1|root,COG0657@2|Bacteria,1RGFY@1224|Proteobacteria	1224|Proteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMD2_k127_395091_28	512565.AMIS_58830	1.615e-12	76.0	COG4188@1|root,COG4188@2|Bacteria,2GMYW@201174|Actinobacteria,4DMCX@85008|Micromonosporales	201174|Actinobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
MMD2_k127_395091_18	509190.Cseg_2356	8.021e-43	164.0	COG1506@1|root,COG1506@2|Bacteria,1R0PB@1224|Proteobacteria,2TYSM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_395091_21	1123276.KB893301_gene4134	6.341e-31	131.0	2DMP1@1|root,32SS8@2|Bacteria,4NQY9@976|Bacteroidetes,47QNE@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
MMD2_k127_395091_16	69395.JQLZ01000005_gene3645	4.07e-44	175.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_395091_11	247634.GPB2148_2019	5.093e-65	229.0	COG0386@1|root,COG0386@2|Bacteria,1RDR8@1224|Proteobacteria,1S3WV@1236|Gammaproteobacteria,1J6RY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione peroxidase	gpwA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
MMD2_k127_395091_31	1038860.AXAP01000084_gene475	1.27e-09	63.0	COG4219@1|root,COG4219@2|Bacteria,1R8I7@1224|Proteobacteria,2U1KK@28211|Alphaproteobacteria,3JS1Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	DUF3471,Peptidase_M56
MMD2_k127_395091_22	1116472.MGMO_103c00040	5.448e-30	126.0	COG4319@1|root,COG4319@2|Bacteria,1RF3P@1224|Proteobacteria,1T94E@1236|Gammaproteobacteria,1XGJI@135618|Methylococcales	135618|Methylococcales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMD2_k127_395091_30	1415780.JPOG01000001_gene601	5.268e-12	69.0	COG5606@1|root,COG5606@2|Bacteria,1NA3S@1224|Proteobacteria,1SAMC@1236|Gammaproteobacteria,1X8MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
MMD2_k127_395091_24	702113.PP1Y_Mpl6642	3.377e-24	107.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_395091_34	160799.PBOR_02950	6.187e-06	53.0	COG1359@1|root,COG1359@2|Bacteria,1VQPZ@1239|Firmicutes,4IPI3@91061|Bacilli,27608@186822|Paenibacillaceae	91061|Bacilli	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
MMD2_k127_4043454_20	1000565.METUNv1_01183	3.484e-40	165.0	COG4520@1|root,COG4520@2|Bacteria,1RIHU@1224|Proteobacteria,2VTAT@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	17kDa_Anti_2,Rick_17kDa_Anti
MMD2_k127_4043454_26	448385.sce5418	9.382e-11	71.0	COG0727@1|root,COG0727@2|Bacteria,1N683@1224|Proteobacteria,42TJ1@68525|delta/epsilon subdivisions,2WQ91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
MMD2_k127_4043454_6	1502724.FF80_02268	1.411e-171	552.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K18926	-	M00715	-	-	ko00000,ko00002,ko02000	2.A.1.3.30	-	-	MFS_1
MMD2_k127_4043454_28	555793.WSK_4186	1.013e-06	59.0	2C42J@1|root,336T0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4043454_21	1267534.KB906758_gene2405	2.582e-39	158.0	COG0491@1|root,COG0491@2|Bacteria,3Y48F@57723|Acidobacteria,2JIRT@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_4043454_5	886293.Sinac_1153	7.549e-175	578.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_4043454_9	627192.SLG_31400	2.294e-104	354.0	COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_4043454_14	627192.SLG_31390	1.39e-61	232.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
MMD2_k127_4043454_27	439235.Dalk_0219	1.403e-09	64.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMD2_k127_4043454_7	1286093.C266_05414	3.202e-169	544.0	COG0477@1|root,COG2814@2|Bacteria,1MUDA@1224|Proteobacteria,2VI2I@28216|Betaproteobacteria,1K0FU@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_4043454_23	1333507.AUTQ01000193_gene4528	3.329e-28	128.0	COG0491@1|root,COG0491@2|Bacteria,1PBS8@1224|Proteobacteria,1RS4P@1236|Gammaproteobacteria,2Q09T@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_4043454_8	396588.Tgr7_2963	2.895e-137	450.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1WW8U@135613|Chromatiales	135613|Chromatiales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
MMD2_k127_4043454_17	1144305.PMI02_01782	5.624e-50	193.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,2TVDN@28211|Alphaproteobacteria,2K2S7@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_4043454_16	1047013.AQSP01000128_gene418	1.009e-51	192.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
MMD2_k127_4043454_18	1415780.JPOG01000001_gene1646	1.315e-42	160.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1X5YX@135614|Xanthomonadales	135614|Xanthomonadales	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
MMD2_k127_4043454_4	396588.Tgr7_1002	3.472e-221	695.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales	135613|Chromatiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
MMD2_k127_4043454_2	396588.Tgr7_1003	1.939e-291	917.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales	135613|Chromatiales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
MMD2_k127_4043454_24	519989.ECTPHS_07252	6.318e-19	90.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales	135613|Chromatiales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
MMD2_k127_4043454_11	1123400.KB904758_gene2378	1.371e-81	281.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,460E5@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
MMD2_k127_4043454_22	713586.KB900536_gene3063	3.394e-32	126.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1WYZR@135613|Chromatiales	135613|Chromatiales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
MMD2_k127_4043454_1	519989.ECTPHS_07267	1.749e-320	995.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
MMD2_k127_4043454_12	62928.azo0745	3.131e-80	276.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,2KV7X@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
MMD2_k127_4043454_15	1265313.HRUBRA_02692	1.49e-52	197.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1J63Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
MMD2_k127_4043454_13	1255043.TVNIR_1418	2.294e-68	233.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1TJD2@1236|Gammaproteobacteria,1WYEP@135613|Chromatiales	135613|Chromatiales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
MMD2_k127_4043454_0	396588.Tgr7_2026	0.0	1041.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1WW7V@135613|Chromatiales	135613|Chromatiales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
MMD2_k127_4043454_25	105559.Nwat_1432	1.211e-12	78.0	COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1WZA1@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
MMD2_k127_4043454_3	388051.AUFE01000007_gene1443	3.14e-236	749.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1K0GW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMD2_k127_4047735_6	349163.Acry_2179	4.629e-28	117.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,2JR9I@204441|Rhodospirillales	204441|Rhodospirillales	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_4047735_3	1163617.SCD_n01434	3.342e-72	266.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1MUAK@1224|Proteobacteria,2WGJC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMD2_k127_4047735_4	935261.JAGL01000040_gene2631	2.044e-56	206.0	COG3473@1|root,COG3473@2|Bacteria,1RC29@1224|Proteobacteria,2U5CE@28211|Alphaproteobacteria,43KBU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	COG3473, Maleate cis-trans isomerase	-	-	4.1.1.76,5.2.1.1	ko:K01799,ko:K06033	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
MMD2_k127_4047735_2	1134474.O59_003941	1.355e-90	308.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,1S0NW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Superoxide dismutase	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
MMD2_k127_4047735_5	1415779.JOMH01000001_gene1473	1.158e-45	169.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1SYIJ@1236|Gammaproteobacteria,1X7E5@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, mercury resistance	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
MMD2_k127_4047735_0	1415779.JOMH01000001_gene1474	9.544e-310	968.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales	135614|Xanthomonadales	P	Heavy metal translocating P-type atpase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
MMD2_k127_4047735_1	1097668.BYI23_B013350	1.792e-108	354.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2VJM3@28216|Betaproteobacteria,1K5G7@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Methionine biosynthesis protein MetW	ubiE_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMD2_k127_4049822_1	1380394.JADL01000001_gene1962	0.0	1274.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2JRJG@204441|Rhodospirillales	204441|Rhodospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07789	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
MMD2_k127_4049822_0	1380394.JADL01000001_gene1963	0.0	1376.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2JQ03@204441|Rhodospirillales	204441|Rhodospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07788	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
MMD2_k127_4049822_6	1218076.BAYB01000019_gene3666	4.81e-114	384.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2VHQP@28216|Betaproteobacteria,1K3XT@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMD2_k127_4049822_9	983917.RGE_16520	2.342e-84	294.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2WF83@28216|Betaproteobacteria,1KP9X@119065|unclassified Burkholderiales	1224|Proteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_4049822_8	1218075.BAYA01000003_gene787	2.27e-89	320.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,1KG4B@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,dCache_1
MMD2_k127_4049822_7	1288826.MSNKSG1_18115	2.343e-106	356.0	COG0438@1|root,COG0438@2|Bacteria,1PDW1@1224|Proteobacteria,1RZIK@1236|Gammaproteobacteria,469U7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMD2_k127_4049822_11	1304275.C41B8_09968	2.165e-68	248.0	COG0438@1|root,COG0438@2|Bacteria,1R7VT@1224|Proteobacteria,1SYK1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMD2_k127_4049822_4	1410628.JNKS01000035_gene1733	1.466e-137	456.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,27JQE@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Asparagine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Asn_synthase,GATase_7
MMD2_k127_4049822_3	1124983.PFLCHA0_c19710	1.095e-179	568.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,1YSEM@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis protein	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMD2_k127_4049822_5	882.DVU_0090	1.258e-129	438.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2WIJX@28221|Deltaproteobacteria,2M7SU@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
MMD2_k127_4049822_10	324602.Caur_1781	4.213e-84	286.0	2AJKK@1|root,31A7Q@2|Bacteria	2|Bacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,Methyltransf_22
MMD2_k127_4049822_13	585394.RHOM_12035	7.033e-05	54.0	2DMX9@1|root,32U7V@2|Bacteria,1W0SU@1239|Firmicutes,24QVG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4049822_2	1207063.P24_15374	8.402e-254	797.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,2JR6D@204441|Rhodospirillales	204441|Rhodospirillales	V	COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMD2_k127_4077641_10	399739.Pmen_3176	3.199e-51	189.0	COG2085@1|root,COG2085@2|Bacteria,1RCXR@1224|Proteobacteria,1S463@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NADP oxidoreductase, coenzyme f420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
MMD2_k127_4077641_8	543728.Vapar_0038	1.43e-72	248.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2W2AU@28216|Betaproteobacteria,4AHNI@80864|Comamonadaceae	28216|Betaproteobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
MMD2_k127_4077641_13	765912.Thimo_2969	5.969e-43	166.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1WY1E@135613|Chromatiales	135613|Chromatiales	O	Thiol disulfide interchange protein	-	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA
MMD2_k127_4077641_2	1123278.KB893444_gene1710	4.725e-176	567.0	COG0624@1|root,COG0624@2|Bacteria,4NEHJ@976|Bacteroidetes,47MC5@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMD2_k127_4077641_11	697282.Mettu_1211	3.457e-47	181.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria,1XDV0@135618|Methylococcales	135618|Methylococcales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD2_k127_4077641_21	1396141.BATP01000018_gene1546	5.287e-06	59.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM,DUF3225,DUF4440,SnoaL_2,SnoaL_3
MMD2_k127_4077641_1	991905.SL003B_2024	1.724e-194	616.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,1MUDV@1224|Proteobacteria,2TRXZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
MMD2_k127_4077641_0	991905.SL003B_2026	1.584e-232	732.0	COG4986@1|root,COG4986@2|Bacteria,1MV85@1224|Proteobacteria,2TTRP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
MMD2_k127_4077641_7	338969.Rfer_1387	2.467e-81	279.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2VQSG@28216|Betaproteobacteria,4AEAD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
MMD2_k127_4077641_20	1395516.PMO01_10150	8.795e-07	59.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1S67S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_4077641_5	344747.PM8797T_08574	5.836e-93	327.0	COG4225@1|root,COG4225@2|Bacteria,2IZFK@203682|Planctomycetes	203682|Planctomycetes	S	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
MMD2_k127_4077641_3	686340.Metal_1984	7.46e-168	554.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T23Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMD2_k127_4077641_6	349521.HCH_00946	3.015e-92	308.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RRT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	response regulator	phoP_1	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_4077641_14	1116472.MGMO_26c00030	1.822e-31	132.0	COG1842@1|root,COG1842@2|Bacteria	2|Bacteria	KT	Phage shock protein A	-	-	-	ko:K03615,ko:K03969,ko:K09749,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,PspA_IM30
MMD2_k127_4077641_15	768671.ThimaDRAFT_1459	3.436e-25	118.0	2CFV2@1|root,32UMX@2|Bacteria,1N3YD@1224|Proteobacteria,1SABG@1236|Gammaproteobacteria,1WZ2C@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4077641_4	768671.ThimaDRAFT_1458	1.1e-132	445.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,1RXGJ@1236|Gammaproteobacteria,1WX7E@135613|Chromatiales	135613|Chromatiales	S	von Willebrand factor, type A	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	VWA_2
MMD2_k127_4077641_18	1007104.SUS17_2414	3.07e-09	69.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4077641_19	555793.WSK_4047	8.659e-09	66.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4077641_16	1007104.SUS17_2415	1.31e-21	105.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,2KCBM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4077641_17	555793.WSK_1435	8.634e-11	68.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4077641_12	1348657.M622_03410	3.076e-46	177.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,2KVZE@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
MMD2_k127_4077641_9	1424334.W822_22580	1.227e-66	245.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
MMD2_k127_4078572_4	420662.Mpe_A1427	1.297e-141	470.0	COG0312@1|root,COG0312@2|Bacteria,1QM7I@1224|Proteobacteria,2VNXI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
MMD2_k127_4078572_1	420662.Mpe_A1428	8.525e-193	612.0	COG0312@1|root,COG0312@2|Bacteria,1NSH6@1224|Proteobacteria,2VJRT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
MMD2_k127_4078572_0	246200.SPO3153	1.267e-239	752.0	COG0654@1|root,COG5274@1|root,COG0654@2|Bacteria,COG5274@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	nah	-	1.14.13.1	ko:K00480	ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R05632,R06915,R06936,R06939	RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8
MMD2_k127_4078572_18	1267533.KB906734_gene3858	1.109e-73	261.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,MetW,Methyltransf_2
MMD2_k127_4078572_15	497964.CfE428DRAFT_1264	4.478e-83	280.0	COG1584@1|root,COG1584@2|Bacteria,46T3N@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM GPR1 FUN34 yaaH family protein	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
MMD2_k127_4078572_25	697282.Mettu_3684	2.46e-21	99.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,1SF7K@1236|Gammaproteobacteria,1XGMP@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4078572_16	1175306.GWL_45930	3.44e-76	259.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,474AV@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
MMD2_k127_4078572_20	234267.Acid_0694	1.587e-57	204.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
MMD2_k127_4078572_8	522306.CAP2UW1_2002	1.332e-113	374.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KQC9@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMD2_k127_4078572_11	1123256.KB907926_gene814	1.234e-98	345.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1X3SH@135614|Xanthomonadales	135614|Xanthomonadales	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMD2_k127_4078572_6	1380394.JADL01000012_gene872	3.716e-125	408.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2TQU1@28211|Alphaproteobacteria,2JQK1@204441|Rhodospirillales	204441|Rhodospirillales	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
MMD2_k127_4078572_3	717785.HYPMC_0592	9.17e-143	461.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2TTJA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMD2_k127_4078572_7	278963.ATWD01000001_gene4210	8.823e-115	387.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
MMD2_k127_4078572_19	1122604.JONR01000025_gene4602	1.268e-67	254.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
MMD2_k127_4078572_26	1230476.C207_06865	4.626e-13	77.0	COG1917@1|root,COG1917@2|Bacteria,1RGZB@1224|Proteobacteria,2U8ED@28211|Alphaproteobacteria,3JZ4I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD2_k127_4078572_14	301.JNHE01000010_gene3468	6.027e-84	289.0	COG0526@1|root,COG0526@2|Bacteria,1NCXZ@1224|Proteobacteria,1RZ3D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
MMD2_k127_4078572_21	247633.GP2143_17796	1.636e-49	190.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4078572_17	247633.GP2143_17791	1.016e-75	269.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4078572_23	247633.GP2143_17801	8.842e-37	143.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4078572_27	1144312.PMI09_02968	2.298e-12	78.0	COG0662@1|root,COG0662@2|Bacteria,1N5XM@1224|Proteobacteria,2VG9U@28211|Alphaproteobacteria,4BNHZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
MMD2_k127_4078572_22	566466.NOR53_677	1.22e-46	183.0	COG0526@1|root,COG0526@2|Bacteria,1N6UU@1224|Proteobacteria,1SEIM@1236|Gammaproteobacteria,1J8D8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_2
MMD2_k127_4078572_12	1442599.JAAN01000037_gene1	1.538e-98	334.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,1RWHH@1236|Gammaproteobacteria,1X5CF@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD2_k127_4078572_2	251221.35213265	5.322e-148	480.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD2_k127_4078572_9	1267535.KB906767_gene904	5.088e-110	363.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
MMD2_k127_4078572_10	266117.Rxyl_2556	8.041e-106	362.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria,4CT9Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Helix-turn-helix domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
MMD2_k127_4078572_5	266117.Rxyl_2557	9.458e-127	415.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria,4CPP8@84995|Rubrobacteria	84995|Rubrobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMD2_k127_4078572_13	1211115.ALIQ01000212_gene3293	3.188e-85	291.0	COG0697@1|root,COG0697@2|Bacteria,1PHRI@1224|Proteobacteria,2TUAQ@28211|Alphaproteobacteria,3NB3U@45404|Beijerinckiaceae	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	MA20_39710	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD2_k127_4078572_24	247634.GPB2148_156	1.458e-24	104.0	COG0620@1|root,COG0620@2|Bacteria,1QJ82@1224|Proteobacteria,1TH64@1236|Gammaproteobacteria,1J9IH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	E COG0620 Methionine synthase II (cobalamin-independent)	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
MMD2_k127_4118765_5	627192.SLG_26300	1.368e-139	452.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4118765_3	1217720.ALOX01000065_gene3924	6.047e-143	465.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,2JU43@204441|Rhodospirillales	204441|Rhodospirillales	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
MMD2_k127_4118765_7	1209072.ALBT01000032_gene2078	1.667e-40	157.0	2DYRQ@1|root,34ATV@2|Bacteria,1PQUZ@1224|Proteobacteria,1ST19@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cytochrome C'	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
MMD2_k127_4118765_6	396588.Tgr7_0552	1.988e-99	338.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WWAK@135613|Chromatiales	135613|Chromatiales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMD2_k127_4118765_10	1276920.ADIAG_00362	0.0001366	53.0	COG0404@1|root,COG0404@2|Bacteria,2GPU4@201174|Actinobacteria,1W8JS@1268|Micrococcaceae	201174|Actinobacteria	E	Aminomethyltransferase folate-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
MMD2_k127_4118765_8	460265.Mnod_2760	1.091e-36	160.0	COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2U1JI@28211|Alphaproteobacteria,1JZC1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM extracellular solute-binding protein family 1	-	-	5.3.3.7	ko:K02020,ko:K22003	ko00660,ko02010,map00660,map02010	M00189	R02244	RC00668	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	SBP_bac_11
MMD2_k127_4118765_0	395964.KE386496_gene2969	2.294e-241	756.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,3NASQ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	F	formate-tetrahydrofolate ligase activity	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
MMD2_k127_4118765_1	107635.AZUO01000001_gene140	1.695e-214	674.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,36XCW@31993|Methylocystaceae	28211|Alphaproteobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMD2_k127_4118765_4	395493.BegalDRAFT_3524	5.381e-140	465.0	COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,460BF@72273|Thiotrichales	72273|Thiotrichales	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMD2_k127_4118765_2	697282.Mettu_1619	5.422e-192	604.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1XEHS@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
MMD2_k127_4118765_9	1122135.KB893141_gene58	7.025e-32	129.0	COG0685@1|root,COG0685@2|Bacteria,1MVWT@1224|Proteobacteria,2TTSF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0685 5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
MMD2_k127_4206544_22	626887.J057_20740	7.97e-24	102.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,463XQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMD2_k127_4206544_21	1134474.O59_002379	8.507e-26	117.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S7A2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4206544_16	1396858.Q666_13125	3.046e-48	184.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S5IS@1236|Gammaproteobacteria,46B06@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4206544_19	765912.Thimo_0967	1.417e-43	172.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,1WW5A@135613|Chromatiales	135613|Chromatiales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
MMD2_k127_4206544_20	1205753.A989_16223	4.611e-31	130.0	COG0271@1|root,COG0271@2|Bacteria,1QCDM@1224|Proteobacteria,1RTFD@1236|Gammaproteobacteria,1X7ES@135614|Xanthomonadales	135614|Xanthomonadales	T	Belongs to the BolA IbaG family	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
MMD2_k127_4206544_18	1283300.ATXB01000002_gene3128	3.397e-45	169.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1XF33@135618|Methylococcales	135618|Methylococcales	D	probably involved in intracellular septation	-	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
MMD2_k127_4206544_9	1123279.ATUS01000001_gene912	3.213e-87	292.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1J4HA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the SUA5 family	yciO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
MMD2_k127_4206544_12	870187.Thini_0535	3.465e-67	235.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,460HE@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
MMD2_k127_4206544_7	396588.Tgr7_2013	2.913e-101	338.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1WW4R@135613|Chromatiales	135613|Chromatiales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
MMD2_k127_4206544_11	713586.KB900536_gene604	1.394e-67	239.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1WW3N@135613|Chromatiales	135613|Chromatiales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
MMD2_k127_4206544_13	768671.ThimaDRAFT_2021	5.37e-63	227.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1WW93@135613|Chromatiales	135613|Chromatiales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMD2_k127_4206544_15	1445613.JALM01000025_gene294	6.72e-55	204.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4E2RZ@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
MMD2_k127_4206544_14	111781.Lepto7376_2197	1.104e-56	201.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria	1117|Cyanobacteria	J	translation initiation inhibitor, yjgF family	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
MMD2_k127_4206544_2	1117379.BABA_03459	3.264e-211	673.0	COG4993@1|root,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli,1ZFCQ@1386|Bacillus	91061|Bacilli	CG	COG4993 Glucose dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_4206544_10	582744.Msip34_2408	3.727e-76	265.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VPAG@28216|Betaproteobacteria,2KMJ2@206350|Nitrosomonadales	206350|Nitrosomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD2_k127_4206544_5	452637.Oter_1901	5.334e-114	383.0	COG0845@1|root,COG0845@2|Bacteria,46UK7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4206544_6	240015.ACP_2502	6.653e-114	372.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_4206544_4	452637.Oter_1814	6.658e-165	550.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_4206544_1	234267.Acid_3297	1.256e-244	781.0	COG0577@1|root,COG0577@2|Bacteria,3Y41Z@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_4206544_3	234267.Acid_5729	7.105e-204	662.0	COG0577@1|root,COG0577@2|Bacteria,3Y3HB@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_4206544_0	861299.J421_5876	2.452e-251	801.0	COG0577@1|root,COG0577@2|Bacteria,1ZUI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_4206544_8	215803.DB30_8369	2.741e-89	302.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2X429@28221|Deltaproteobacteria,2YY1P@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMD2_k127_4206544_17	1340493.JNIF01000003_gene4408	3.309e-47	173.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD2_k127_4235346_18	903818.KI912268_gene3208	2.297e-78	284.0	COG1472@1|root,COG1472@2|Bacteria,3Y2YR@57723|Acidobacteria	57723|Acidobacteria	G	PFAM glycoside hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
MMD2_k127_4235346_25	136993.KB900627_gene392	1.42e-24	113.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4235346_24	639030.JHVA01000001_gene1885	5.508e-25	115.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4235346_11	357808.RoseRS_2741	1.377e-126	439.0	COG0388@1|root,COG0388@2|Bacteria,2G6KM@200795|Chloroflexi,375XY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
MMD2_k127_4235346_3	335283.Neut_2188	3.583e-212	677.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,2VNM0@28216|Betaproteobacteria,37405@32003|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Orn DAP Arg decarboxylase 2	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
MMD2_k127_4235346_6	357808.RoseRS_1218	6.94e-170	537.0	COG1899@1|root,COG1899@2|Bacteria,2G7R7@200795|Chloroflexi,374VZ@32061|Chloroflexia	32061|Chloroflexia	O	PFAM deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
MMD2_k127_4235346_12	518766.Rmar_1511	3.198e-125	421.0	COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
MMD2_k127_4235346_23	351607.Acel_1704	4.941e-29	125.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4ESYT@85013|Frankiales	201174|Actinobacteria	K	Uncharacterized ACR, COG1678	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
MMD2_k127_4235346_14	1123242.JH636434_gene4996	5.035e-100	333.0	COG1432@1|root,COG1432@2|Bacteria,2IY4C@203682|Planctomycetes	203682|Planctomycetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
MMD2_k127_4235346_19	76114.ebA6983	8.332e-65	231.0	COG3931@1|root,COG3931@2|Bacteria,1PWF0@1224|Proteobacteria,2VZYZ@28216|Betaproteobacteria,2KXSX@206389|Rhodocyclales	206389|Rhodocyclales	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
MMD2_k127_4235346_10	1232410.KI421415_gene2974	6.057e-127	419.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria,43UJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
MMD2_k127_4235346_8	314230.DSM3645_13895	5.708e-159	514.0	COG0189@1|root,COG0189@2|Bacteria,2J2AV@203682|Planctomycetes	203682|Planctomycetes	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RLAN,RimK
MMD2_k127_4235346_17	589865.DaAHT2_0310	1.019e-78	272.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria,2MNBG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
MMD2_k127_4235346_22	96561.Dole_1891	2.738e-37	150.0	COG0454@1|root,COG1181@1|root,COG0456@2|Bacteria,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2MHWK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
MMD2_k127_4235346_16	1121405.dsmv_1837	1.94e-83	293.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2MHWK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
MMD2_k127_4235346_13	1121374.KB891575_gene1185	3.112e-113	374.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,1SKJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
MMD2_k127_4235346_4	1121374.KB891575_gene1184	1.661e-180	575.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1S5FN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Radical SAM superfamily	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
MMD2_k127_4235346_7	1121017.AUFG01000010_gene1661	9.079e-168	537.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4FEQ1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMD2_k127_4235346_15	1128421.JAGA01000002_gene123	1.624e-94	329.0	COG0297@1|root,COG0297@2|Bacteria,2NP1F@2323|unclassified Bacteria	2|Bacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	iLJ478.TM0895	Glyco_transf_5,Glycos_transf_1
MMD2_k127_4235346_9	713587.THITH_10055	4.613e-147	481.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1WWBR@135613|Chromatiales	135613|Chromatiales	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
MMD2_k127_4235346_5	396588.Tgr7_2073	5.015e-171	548.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
MMD2_k127_4235346_0	519989.ECTPHS_08101	2.461e-302	943.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1SYH1@1236|Gammaproteobacteria,1X2II@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
MMD2_k127_4235346_21	1408164.MOLA814_00021	6.016e-51	186.0	2E7KN@1|root,3322N@2|Bacteria,1N6FH@1224|Proteobacteria,2WFF2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1097
MMD2_k127_4235346_20	41431.PCC8801_3978	1.811e-62	226.0	COG0564@1|root,COG0564@2|Bacteria,1G1W7@1117|Cyanobacteria,3KGM7@43988|Cyanothece	1117|Cyanobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
MMD2_k127_4235346_2	1049564.TevJSym_ac00500	3.091e-226	751.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1J77P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.41,3.2.1.68	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
MMD2_k127_4235346_1	1288494.EBAPG3_21170	3.193e-282	893.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria,372UR@32003|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
MMD2_k127_42392_8	1121935.AQXX01000119_gene4775	4.162e-82	281.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1XI47@135619|Oceanospirillales	135619|Oceanospirillales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMD2_k127_42392_4	1123033.ARNF01000052_gene1018	2.032e-147	478.0	COG0477@1|root,COG2814@2|Bacteria,1NGB4@1224|Proteobacteria,1RZ75@1236|Gammaproteobacteria,3NSX2@468|Moraxellaceae	1236|Gammaproteobacteria	EGP	MFS/sugar transport protein	phlE	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMD2_k127_42392_1	627192.SLG_20060	2.673e-207	664.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2K3Q1@204457|Sphingomonadales	204457|Sphingomonadales	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
MMD2_k127_42392_16	627192.SLG_20050	1.109e-17	86.0	2FHPP@1|root,349H9@2|Bacteria,1NC8W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_42392_12	1408164.MOLA814_00003	4.236e-40	156.0	COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,2VIDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome c oxidase (Subunit II)	coxM	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
MMD2_k127_42392_15	314287.GB2207_11253	4.071e-27	120.0	COG3038@1|root,COG3038@2|Bacteria,1NFHR@1224|Proteobacteria	1224|Proteobacteria	C	Prokaryotic cytochrome b561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
MMD2_k127_42392_7	502025.Hoch_5285	1.058e-103	348.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42MQV@68525|delta/epsilon subdivisions,2X1WZ@28221|Deltaproteobacteria,2YZ4N@29|Myxococcales	28221|Deltaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
MMD2_k127_42392_17	575588.ACPN01000134_gene1945	0.0003912	43.0	2A2R8@1|root,30R45@2|Bacteria,1QBY9@1224|Proteobacteria,1T7JH@1236|Gammaproteobacteria,3NSE4@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_42392_2	477228.YO5_10210	6.876e-193	612.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1Z1W2@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	clsC	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
MMD2_k127_42392_5	323848.Nmul_A0164	2.113e-120	396.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMD2_k127_42392_14	1449049.JONW01000006_gene3277	1.012e-28	119.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2UDEK@28211|Alphaproteobacteria,2KGZA@204458|Caulobacterales	204458|Caulobacterales	S	PFAM Membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
MMD2_k127_42392_10	509190.Cseg_2093	1.67e-47	187.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2UH72@28211|Alphaproteobacteria,2KK54@204458|Caulobacterales	204458|Caulobacterales	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
MMD2_k127_42392_11	426355.Mrad2831_5225	1.449e-40	156.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2TYMV@28211|Alphaproteobacteria,1JUMR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD2_k127_42392_9	426355.Mrad2831_5224	2.864e-69	259.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TSPY@28211|Alphaproteobacteria,1JR17@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_9
MMD2_k127_42392_6	743299.Acife_1337	1.632e-105	363.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
MMD2_k127_42392_3	627192.SLG_31420	1.475e-184	604.0	COG0551@1|root,COG0551@2|Bacteria,1NU8S@1224|Proteobacteria,2TWWM@28211|Alphaproteobacteria,2K3KC@204457|Sphingomonadales	204457|Sphingomonadales	L	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
MMD2_k127_42392_13	627192.SLG_31400	3.292e-36	159.0	COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_4283430_7	247633.GP2143_17671	2.114e-69	237.0	COG4101@1|root,COG4101@2|Bacteria,1RB8W@1224|Proteobacteria	1224|Proteobacteria	G	Cupin 2, conserved barrel domain protein	MA20_44940	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD2_k127_4283430_0	234267.Acid_2813	5.847e-174	580.0	COG0577@1|root,COG0577@2|Bacteria,3Y6QF@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_4283430_4	99598.Cal7507_4386	6.154e-94	321.0	COG0477@1|root,COG2814@2|Bacteria,1G2J6@1117|Cyanobacteria,1HRV6@1161|Nostocales	1117|Cyanobacteria	EGP	PFAM Major facilitator superfamily MFS-1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMD2_k127_4283430_1	1348657.M622_14795	4.623e-161	518.0	COG0075@1|root,COG0075@2|Bacteria,1PM38@1224|Proteobacteria,2VHNM@28216|Betaproteobacteria,2KVAR@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMD2_k127_4283430_6	40571.JOEA01000003_gene3591	7.932e-75	258.0	COG3647@1|root,COG3647@2|Bacteria,2IATE@201174|Actinobacteria,4E3YF@85010|Pseudonocardiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
MMD2_k127_4283430_12	1384056.N787_03385	8.057e-24	103.0	29E9B@1|root,3017D@2|Bacteria,1QCYG@1224|Proteobacteria,1T8SH@1236|Gammaproteobacteria,1XB63@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4283430_8	331869.BAL199_24899	7.861e-65	233.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,2VGIH@28211|Alphaproteobacteria,4BQJK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
MMD2_k127_4283430_14	1545915.JROG01000004_gene1689	7.82e-13	74.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K18E@204457|Sphingomonadales	204457|Sphingomonadales	CG	Dehydrogenase	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
MMD2_k127_4283430_13	1042377.AFPJ01000032_gene2774	1.572e-15	85.0	COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,1SF8E@1236|Gammaproteobacteria,46CD6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4283430_2	1122599.AUGR01000010_gene1046	1.468e-159	512.0	28JVF@1|root,2Z9KD@2|Bacteria,1MXZ6@1224|Proteobacteria,1RY7E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4283430_5	323261.Noc_1208	3.906e-82	282.0	28HJ1@1|root,2Z7UB@2|Bacteria,1R3FN@1224|Proteobacteria,1S37A@1236|Gammaproteobacteria,1WXEJ@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4283430_9	1122169.AREN01000004_gene424	2.898e-63	235.0	COG1196@1|root,COG1196@2|Bacteria,1MXPN@1224|Proteobacteria,1S0WY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4283430_10	1161401.ASJA01000001_gene341	2.178e-36	157.0	COG3764@1|root,COG3764@2|Bacteria,1P806@1224|Proteobacteria,2U0A5@28211|Alphaproteobacteria,43YMI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
MMD2_k127_4283430_3	1117647.M5M_19015	9.586e-121	407.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,1J5IX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
MMD2_k127_4381638_8	392500.Swoo_3378	1.998e-21	104.0	2C3X5@1|root,32RCX@2|Bacteria,1RKW4@1224|Proteobacteria,1S73W@1236|Gammaproteobacteria,2QC0X@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4381638_7	1385935.N836_17780	2.894e-32	130.0	COG2153@1|root,COG2153@2|Bacteria,1G6TQ@1117|Cyanobacteria,1HBVA@1150|Oscillatoriales	1117|Cyanobacteria	S	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
MMD2_k127_4381638_1	1123393.KB891318_gene2177	5.62e-96	322.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2VH8U@28216|Betaproteobacteria,1KSBU@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
MMD2_k127_4381638_0	1121948.AUAC01000008_gene821	3.613e-134	432.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,43WME@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMD2_k127_4381638_2	69395.JQLZ01000003_gene51	2.91e-87	297.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,2TRDF@28211|Alphaproteobacteria,2KIIH@204458|Caulobacterales	204458|Caulobacterales	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
MMD2_k127_4381638_5	686340.Metal_1207	4.15e-67	246.0	COG3637@1|root,COG3637@2|Bacteria,1R64D@1224|Proteobacteria,1S325@1236|Gammaproteobacteria,1XDN4@135618|Methylococcales	135618|Methylococcales	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
MMD2_k127_4381638_3	1198452.Jab_1c17820	1.855e-79	270.0	COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,2VQNM@28216|Betaproteobacteria,474VF@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Redoxin	bcp_2	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
MMD2_k127_4381638_6	159087.Daro_0623	1.257e-43	163.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,2KX2P@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMD2_k127_4381638_4	414684.RC1_0028	1.911e-75	266.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2JPVS@204441|Rhodospirillales	204441|Rhodospirillales	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
MMD2_k127_4386765_10	1121124.JNIX01000009_gene2943	1.73e-127	417.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMD2_k127_4386765_24	1095769.CAHF01000015_gene2793	4.182e-64	222.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2VRD4@28216|Betaproteobacteria,477DK@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	gloA3	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_4386765_5	187272.Mlg_1302	8.648e-183	583.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1WW94@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMD2_k127_4386765_7	1254432.SCE1572_08525	2.425e-158	518.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42MPR@68525|delta/epsilon subdivisions,2WNM3@28221|Deltaproteobacteria,2Z06N@29|Myxococcales	28221|Deltaproteobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
MMD2_k127_4386765_32	234267.Acid_2001	2.957e-27	117.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
MMD2_k127_4386765_41	754027.HMPREF9554_02099	1.135e-08	62.0	COG1585@1|root,COG1585@2|Bacteria,2J89B@203691|Spirochaetes	203691|Spirochaetes	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
MMD2_k127_4386765_11	290397.Adeh_0881	3.937e-127	416.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WKYT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
MMD2_k127_4386765_21	580332.Slit_2316	4.12e-73	257.0	COG4912@1|root,COG4912@2|Bacteria,1PX21@1224|Proteobacteria,2WCJR@28216|Betaproteobacteria,44W8K@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
MMD2_k127_4386765_22	1496688.ER33_12165	1.532e-72	251.0	COG0438@1|root,COG0438@2|Bacteria,1GA3P@1117|Cyanobacteria,22TYE@167375|Cyanobium	1117|Cyanobacteria	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
MMD2_k127_4386765_28	1298593.TOL_3644	3.373e-44	170.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1XKC3@135619|Oceanospirillales	135619|Oceanospirillales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
MMD2_k127_4386765_0	713586.KB900536_gene112	0.0	1051.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1WWU3@135613|Chromatiales	135613|Chromatiales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
MMD2_k127_4386765_38	1449049.JONW01000010_gene3544	2.398e-13	76.0	2FFPQ@1|root,33DCS@2|Bacteria,1NM7U@1224|Proteobacteria,2VGJ2@28211|Alphaproteobacteria,2KK6H@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4386765_33	1117319.PSPO_08104	7.279e-25	106.0	COG1476@1|root,COG1476@2|Bacteria,1N7BB@1224|Proteobacteria,1SCG8@1236|Gammaproteobacteria,2Q3A7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
MMD2_k127_4386765_30	234267.Acid_2858	8.296e-37	146.0	COG3797@1|root,COG3797@2|Bacteria,3Y5RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
MMD2_k127_4386765_34	314345.SPV1_08761	5.572e-19	90.0	2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
MMD2_k127_4386765_19	234267.Acid_2431	1.162e-79	276.0	2F63Z@1|root,33YN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4386765_40	765910.MARPU_00350	6.22e-10	63.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1WZ7B@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMD2_k127_4386765_17	768671.ThimaDRAFT_0706	6.284e-88	301.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1WX0P@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMD2_k127_4386765_31	1304275.C41B8_11810	6.855e-29	123.0	COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,1RQPX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	rimJ	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
MMD2_k127_4386765_25	1177179.A11A3_03544	1.435e-61	219.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,1XJSJ@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
MMD2_k127_4386765_3	1123400.KB904764_gene2458	1.405e-230	726.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,461XX@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMD2_k127_4386765_6	266117.Rxyl_0238	6.621e-169	546.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4CPJR@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMD2_k127_4386765_4	1123242.JH636435_gene3071	8.4e-216	677.0	COG0436@1|root,COG0436@2|Bacteria,2IXM3@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_4386765_29	1121015.N789_02320	4.393e-43	178.0	COG0346@1|root,COG0346@2|Bacteria,1N1D4@1224|Proteobacteria,1S7IY@1236|Gammaproteobacteria,1X7V3@135614|Xanthomonadales	135614|Xanthomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_4386765_8	105559.Nwat_2038	1.531e-156	507.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales	135613|Chromatiales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
MMD2_k127_4386765_35	1121015.N789_07710	8.652e-16	85.0	COG1846@1|root,COG1846@2|Bacteria,1RJ2M@1224|Proteobacteria,1S63D@1236|Gammaproteobacteria,1XAD8@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMD2_k127_4386765_20	391735.Veis_4833	2.098e-76	270.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,4AAUQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMD2_k127_4386765_1	402626.Rpic_4543	0.0	1025.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1K39R@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
MMD2_k127_4386765_13	1123276.KB893245_gene1060	6.963e-116	386.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,47N08@768503|Cytophagia	976|Bacteroidetes	EGP	Major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
MMD2_k127_4386765_9	1336208.JADY01000001_gene936	2.785e-149	489.0	COG1506@1|root,COG1506@2|Bacteria,1R968@1224|Proteobacteria,2TXT1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
MMD2_k127_4386765_16	870187.Thini_3452	2.327e-101	340.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,460V0@72273|Thiotrichales	72273|Thiotrichales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
MMD2_k127_4386765_23	1121921.KB898709_gene315	2.552e-69	244.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,1RZ89@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	belongs to the bacterial solute-binding protein 3 family	fliY	-	-	ko:K02030,ko:K02424,ko:K10036	ko02010,map02010	M00227,M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.2	-	-	SBP_bac_3
MMD2_k127_4386765_42	626887.J057_04331	1.594e-08	62.0	COG5662@1|root,COG5662@2|Bacteria,1NGBV@1224|Proteobacteria,1SGXN@1236|Gammaproteobacteria,46BR4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMD2_k127_4386765_43	1049564.TevJSym_ad01050	1.874e-07	63.0	COG0810@1|root,COG0810@2|Bacteria,1NH16@1224|Proteobacteria	1224|Proteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMD2_k127_4386765_39	55601.VANGNB10_cI1313c	8.743e-12	77.0	COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,1RQPV@1236|Gammaproteobacteria,1XTNF@135623|Vibrionales	135623|Vibrionales	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMD2_k127_4386765_27	1123261.AXDW01000025_gene1759	1.879e-50	193.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S1WE@1236|Gammaproteobacteria,1X9QR@135614|Xanthomonadales	135614|Xanthomonadales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD2_k127_4386765_18	1122604.JONR01000004_gene764	2.024e-86	309.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1X3Y5@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMD2_k127_4386765_12	195250.CM001776_gene3588	1.635e-126	411.0	COG0037@1|root,COG0037@2|Bacteria,1G2S7@1117|Cyanobacteria	1117|Cyanobacteria	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	-	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
MMD2_k127_4386765_26	614083.AWQR01000001_gene3031	1.817e-51	198.0	COG0515@1|root,COG0745@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912,ko:K12132	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	HAMP,Pkinase
MMD2_k127_4386765_36	551275.KB899545_gene2689	8.367e-15	82.0	COG2867@1|root,COG2867@2|Bacteria,1P2TF@1224|Proteobacteria,2UUFJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
MMD2_k127_4386765_14	335659.S23_20060	6.276e-104	354.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria,3JVFH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
MMD2_k127_4386765_2	1238182.C882_1247	2.612e-288	899.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,2JQ7K@204441|Rhodospirillales	204441|Rhodospirillales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
MMD2_k127_4386765_15	402881.Plav_1578	2.257e-103	342.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria,1JNV9@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
MMD2_k127_4386765_37	323261.Noc_0214	1.733e-14	76.0	292KW@1|root,2ZQ4T@2|Bacteria,1PAY1@1224|Proteobacteria,1SVTB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
MMD2_k127_4386765_44	1234364.AMSF01000082_gene2971	0.0003851	45.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1X32G@135614|Xanthomonadales	135614|Xanthomonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
MMD2_k127_441849_36	555793.WSK_1442	3.08e-14	79.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_17	646529.Desaci_3593	7.183e-64	237.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,2610Z@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_441849_24	1236959.BAMT01000015_gene2850	2.89e-25	117.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_32	1040989.AWZU01000029_gene4335	8.015e-17	85.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,3K43P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_20	1205680.CAKO01000006_gene3271	5.316e-54	193.0	COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein possibly involved in utilization of glycolate and propanediol	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
MMD2_k127_441849_10	1089552.KI911559_gene2762	4.715e-118	387.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TRG7@28211|Alphaproteobacteria,2JRQR@204441|Rhodospirillales	204441|Rhodospirillales	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
MMD2_k127_441849_22	1173029.JH980292_gene2278	1.301e-31	127.0	COG3788@1|root,COG3788@2|Bacteria,1G73Q@1117|Cyanobacteria,1HB5A@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM MAPEG family	-	GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016740,GO:0016765,GO:0042221,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	MAPEG
MMD2_k127_441849_21	555793.WSK_1989	3.274e-35	139.0	2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2UH5V@28211|Alphaproteobacteria,2K5Y7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_30	1472418.BBJC01000004_gene1789	2.549e-19	94.0	2CBAE@1|root,31814@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_7	796606.BMMGA3_12815	4.43e-157	509.0	COG2031@1|root,COG2031@2|Bacteria,1TPCQ@1239|Firmicutes,4HAQF@91061|Bacilli,1ZECR@1386|Bacillus	91061|Bacilli	I	Short chain fatty acid transporter	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
MMD2_k127_441849_29	861299.J421_5905	6.669e-20	98.0	2AC8C@1|root,311T1@2|Bacteria,1ZU75@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_13	1134474.O59_000780	5.356e-79	274.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,1FH13@10|Cellvibrio	1236|Gammaproteobacteria	S	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
MMD2_k127_441849_0	349124.Hhal_1070	2.433e-229	719.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,1WWIP@135613|Chromatiales	135613|Chromatiales	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
MMD2_k127_441849_9	395493.BegalDRAFT_1700	1.479e-120	406.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,46076@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
MMD2_k127_441849_31	686340.Metal_3991	1.875e-18	100.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1XG7Q@135618|Methylococcales	135618|Methylococcales	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
MMD2_k127_441849_15	1163617.SCD_n01660	5.812e-70	243.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
MMD2_k127_441849_25	1340493.JNIF01000003_gene3475	1.081e-24	108.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_441849_35	379066.GAU_2319	1.498e-14	84.0	COG2010@1|root,COG2010@2|Bacteria,1ZV02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMD2_k127_441849_34	627192.SLG_09870	4.014e-16	85.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_23	627192.SLG_09880	3.145e-26	117.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_38	1340493.JNIF01000003_gene2122	3.133e-12	74.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_27	1335760.ASTG01000003_gene1750	7.492e-23	114.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_26	1346791.M529_07045	2.421e-24	113.0	2919Q@1|root,2ZNWS@2|Bacteria,1NAF5@1224|Proteobacteria,2U3AC@28211|Alphaproteobacteria,2KEWN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_1	1082931.KKY_2582	3.265e-202	645.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
MMD2_k127_441849_4	383372.Rcas_3335	4.767e-180	576.0	COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi,376IG@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1,6.2.1.3	ko:K01897,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMD2_k127_441849_5	1040989.AWZU01000035_gene1778	3.705e-176	565.0	COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,3JW76@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMD2_k127_441849_11	1050202.KB913024_gene1462	1.349e-115	385.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,4084I@622450|Actinopolysporales	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE2	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMD2_k127_441849_2	1038860.AXAP01000018_gene3108	1.096e-188	609.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_441849_14	926549.KI421517_gene3983	3.216e-75	263.0	COG0715@1|root,COG0715@2|Bacteria,4NETN@976|Bacteroidetes,47JG1@768503|Cytophagia	976|Bacteroidetes	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
MMD2_k127_441849_28	1101195.Meth11DRAFT_1464	4.47e-21	97.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_33	1040989.AWZU01000029_gene4334	2.753e-16	90.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,3K390@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_40	555793.WSK_1990	1.865e-05	53.0	2CBFC@1|root,32RYI@2|Bacteria,1N0T4@1224|Proteobacteria,2UEZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_441849_39	234267.Acid_6849	2.054e-11	70.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,DHC
MMD2_k127_441849_6	234267.Acid_6848	1.854e-163	536.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	mdlC	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMD2_k127_441849_16	402626.Rpic_4126	1.738e-69	250.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VQ62@28216|Betaproteobacteria,1K2D4@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
MMD2_k127_441849_18	1163408.UU9_06809	1.194e-63	241.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1X55J@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_4,Response_reg
MMD2_k127_441849_37	401053.AciPR4_1659	8.926e-14	85.0	COG1846@1|root,COG1846@2|Bacteria,3Y97P@57723|Acidobacteria,2JNFY@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMD2_k127_441849_3	1232437.KL661978_gene3781	1.078e-182	613.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,1RJUD@1224|Proteobacteria,42P27@68525|delta/epsilon subdivisions,2WK9Y@28221|Deltaproteobacteria,2MJZE@213118|Desulfobacterales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_8,TonB_dep_Rec,zinc_ribbon_4
MMD2_k127_441849_8	933262.AXAM01000021_gene459	1.048e-147	495.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MJZH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
MMD2_k127_441849_19	1380394.JADL01000009_gene3112	3.259e-57	208.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria,2JSP4@204441|Rhodospirillales	204441|Rhodospirillales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMD2_k127_441849_12	519989.ECTPHS_03592	1.095e-109	379.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1WX8V@135613|Chromatiales	135613|Chromatiales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
MMD2_k127_4481157_9	94624.Bpet0412	1.593e-109	361.0	COG1116@1|root,COG1116@2|Bacteria,1MUYG@1224|Proteobacteria,2VHDU@28216|Betaproteobacteria,3T2MF@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
MMD2_k127_4481157_8	94624.Bpet0411	1.827e-115	380.0	COG0600@1|root,COG0600@2|Bacteria,1PC26@1224|Proteobacteria,2VJ97@28216|Betaproteobacteria,3T3G2@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
MMD2_k127_4481157_12	639030.JHVA01000001_gene2163	2.22e-52	189.0	COG2080@1|root,COG2080@2|Bacteria,3Y4U1@57723|Acidobacteria,2JMWP@204432|Acidobacteriia	204432|Acidobacteriia	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMD2_k127_4481157_4	1380394.JADL01000013_gene573	4.22e-145	506.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2JPB3@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
MMD2_k127_4481157_21	627192.SLG_09880	2.893e-18	96.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4481157_6	234267.Acid_2032	2.65e-125	415.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_4481157_10	886293.Sinac_1155	1.2e-74	270.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
MMD2_k127_4481157_3	472759.Nhal_0144	1.531e-146	477.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RSN1@1236|Gammaproteobacteria,1WVUQ@135613|Chromatiales	135613|Chromatiales	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
MMD2_k127_4481157_7	309807.SRU_2005	3.858e-117	391.0	COG0627@1|root,COG0627@2|Bacteria,4NIU8@976|Bacteroidetes	976|Bacteroidetes	E	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
MMD2_k127_4481157_19	1415779.JOMH01000001_gene1464	2.249e-38	153.0	293ZC@1|root,2ZREC@2|Bacteria,1RDYU@1224|Proteobacteria,1S4U7@1236|Gammaproteobacteria,1X7U5@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4481157_0	234267.Acid_4983	8.629e-193	626.0	COG1620@1|root,COG1620@2|Bacteria,3Y2ZA@57723|Acidobacteria	57723|Acidobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
MMD2_k127_4481157_14	330214.NIDE0156	3.704e-47	176.0	COG2154@1|root,COG2154@2|Bacteria	2|Bacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
MMD2_k127_4481157_2	1469607.KK073768_gene4791	2.338e-156	503.0	COG1409@1|root,COG1409@2|Bacteria,1G4KM@1117|Cyanobacteria,1HNI0@1161|Nostocales	1117|Cyanobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
MMD2_k127_4481157_18	472759.Nhal_2115	4.47e-41	157.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMD2_k127_4481157_11	314278.NB231_04625	1.958e-53	192.0	COG0664@1|root,COG0664@2|Bacteria,1NI7I@1224|Proteobacteria,1SP73@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
MMD2_k127_4481157_1	472759.Nhal_0109	4.963e-164	527.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1WZVM@135613|Chromatiales	135613|Chromatiales	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
MMD2_k127_4481157_5	225937.HP15_1322	1.019e-125	415.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMD2_k127_4481157_20	765913.ThidrDRAFT_0731	4.032e-22	104.0	COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,1WZDM@135613|Chromatiales	135613|Chromatiales	K	MerR HTH family regulatory protein	-	-	-	ko:K18997	-	-	-	-	ko00000,ko03036	-	-	-	MerR_2
MMD2_k127_4481157_17	765914.ThisiDRAFT_0925	1.325e-42	159.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1WX0B@135613|Chromatiales	135613|Chromatiales	O	heat shock protein DnaJ	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
MMD2_k127_4484682_0	765914.ThisiDRAFT_1157	0.0	1056.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW0R@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
MMD2_k127_4484682_13	1121013.P873_11245	2.003e-96	331.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1XCGD@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
MMD2_k127_4484682_16	1187851.A33M_3230	1.302e-79	275.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	PDZ DHR GLGF domain protein	MA20_20705	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
MMD2_k127_4484682_46	1530186.JQEY01000011_gene2730	6.006e-18	89.0	COG3909@1|root,COG3909@2|Bacteria,1N1E5@1224|Proteobacteria,2U9A1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
MMD2_k127_4484682_28	1123229.AUBC01000011_gene2326	5.326e-44	174.0	COG1988@1|root,COG1988@2|Bacteria,1QK5N@1224|Proteobacteria,2U680@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
MMD2_k127_4484682_41	644968.DFW101_0020	8.933e-23	110.0	2AHM7@1|root,317Z3@2|Bacteria,1PZHH@1224|Proteobacteria,435Z7@68525|delta/epsilon subdivisions,2X0GI@28221|Deltaproteobacteria,2MC94@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4484682_24	596151.DesfrDRAFT_1000	6.85e-50	186.0	29XVI@1|root,30JMT@2|Bacteria,1R14U@1224|Proteobacteria,43D69@68525|delta/epsilon subdivisions,2X8D0@28221|Deltaproteobacteria,2MA0G@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Cytochrome b	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
MMD2_k127_4484682_9	596152.DesU5LDRAFT_2640	1.609e-128	418.0	COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2M9BS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Molybdopterin dehydrogenase, FAD-binding	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMD2_k127_4484682_18	941449.dsx2_3134	7.578e-71	246.0	COG2080@1|root,COG2080@2|Bacteria,1N1KQ@1224|Proteobacteria,42UD3@68525|delta/epsilon subdivisions,2WPH9@28221|Deltaproteobacteria,2M9N0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	2Fe-2S -binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
MMD2_k127_4484682_7	702113.PP1Y_AT11378	1.748e-134	460.0	COG1629@1|root,COG4771@2|Bacteria,1NS8W@1224|Proteobacteria,2UNRM@28211|Alphaproteobacteria,2K8WE@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	TonB_dep_Rec
MMD2_k127_4484682_20	498211.CJA_1597	4.131e-60	212.0	29A26@1|root,2ZX3K@2|Bacteria,1RFE8@1224|Proteobacteria,1S7AB@1236|Gammaproteobacteria,1FI97@10|Cellvibrio	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4484682_34	1236959.BAMT01000015_gene2851	2.959e-34	150.0	2BUPI@1|root,32Q0I@2|Bacteria,1PJP2@1224|Proteobacteria,2W82W@28216|Betaproteobacteria,2KNJ8@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4484682_14	1217720.ALOX01000034_gene336	3.042e-84	303.0	COG1506@1|root,COG1506@2|Bacteria,1R968@1224|Proteobacteria,2TXT1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
MMD2_k127_4484682_8	243365.CV_1007	2.445e-130	424.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,2KQPE@206351|Neisseriales	206351|Neisseriales	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
MMD2_k127_4484682_31	1123023.JIAI01000001_gene6179	4.069e-38	154.0	COG0702@1|root,COG0702@2|Bacteria,2IH9U@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
MMD2_k127_4484682_43	670307.HYPDE_26878	2.339e-21	105.0	COG2197@1|root,COG2197@2|Bacteria,1NC01@1224|Proteobacteria,2URU3@28211|Alphaproteobacteria,3N8EV@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4484682_3	1267533.KB906735_gene4667	1.295e-155	506.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
MMD2_k127_4484682_1	272630.MexAM1_META1p1858	7.481e-295	925.0	COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria,2TVIW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	glucan 1,4-alpha-glucosidase	cga	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_N,Glyco_hydro_15
MMD2_k127_4484682_35	1101192.KB910516_gene210	1.601e-33	141.0	COG2084@1|root,COG2084@2|Bacteria,1MV27@1224|Proteobacteria,2TTCZ@28211|Alphaproteobacteria,1JTTQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
MMD2_k127_4484682_6	1207063.P24_04035	1.15e-138	467.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2TS7J@28211|Alphaproteobacteria,2JQWQ@204441|Rhodospirillales	204441|Rhodospirillales	P	PhoD-like phosphatase, N-terminal domain	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
MMD2_k127_4484682_38	526225.Gobs_2976	6.184e-28	119.0	COG3427@1|root,COG3427@2|Bacteria,2ISBF@201174|Actinobacteria,4EWI5@85013|Frankiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMD2_k127_4484682_39	1492737.FEM08_21710	3.527e-26	119.0	COG1714@1|root,COG1714@2|Bacteria,4NWCH@976|Bacteroidetes,1IBYF@117743|Flavobacteriia	976|Bacteroidetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMD2_k127_4484682_4	502025.Hoch_6664	1.76e-150	489.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,433Y1@68525|delta/epsilon subdivisions,2X41I@28221|Deltaproteobacteria,2YXYJ@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMD2_k127_4484682_2	391625.PPSIR1_22471	5.237e-170	561.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YXKT@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMD2_k127_4484682_45	1297863.APJF01000021_gene180	8.273e-19	94.0	COG4944@1|root,COG4944@2|Bacteria,1RD4P@1224|Proteobacteria,2U8EX@28211|Alphaproteobacteria,3K3T5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
MMD2_k127_4484682_25	420324.KI912063_gene6835	9.62e-50	183.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2UA8J@28211|Alphaproteobacteria,1JVKM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_4484682_33	1297863.APJF01000021_gene171	1.706e-37	143.0	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2UJ9X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Predicted integral membrane protein (DUF2282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
MMD2_k127_4484682_10	1297863.APJF01000021_gene170	9.344e-111	370.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2TRZJ@28211|Alphaproteobacteria,3JR0V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
MMD2_k127_4484682_22	420324.KI912063_gene6832	1.585e-53	199.0	COG3219@1|root,COG3219@2|Bacteria,1PSSN@1224|Proteobacteria,2UVBT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
MMD2_k127_4484682_23	1297863.APJF01000021_gene169	5.233e-51	185.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2TVZ9@28211|Alphaproteobacteria,3JRVF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
MMD2_k127_4484682_37	1087481.AGFX01000041_gene924	1.322e-29	131.0	COG1748@1|root,COG1748@2|Bacteria,1V1T1@1239|Firmicutes,4HG5Q@91061|Bacilli,26SRA@186822|Paenibacillaceae	91061|Bacilli	E	Saccharopine dehydrogenase	lyS1	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
MMD2_k127_4484682_52	390235.PputW619_3100	0.0005026	49.0	COG1422@1|root,COG1422@2|Bacteria,1RJ93@1224|Proteobacteria,1SHF0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1090)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4484682_36	1396858.Q666_10415	1.884e-33	132.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,1SAPM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4484682_5	1280948.HY36_06075	3.057e-140	461.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TURI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Multi-copper	-	-	1.3.3.5	ko:K08100	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
MMD2_k127_4484682_29	1041146.ATZB01000034_gene561	2.605e-41	155.0	COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,2V9XZ@28211|Alphaproteobacteria,4BKA0@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
MMD2_k127_4484682_44	665571.STHERM_c14960	4.59e-19	95.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4484682_49	1042326.AZNV01000018_gene1733	5.358e-13	75.0	COG2372@1|root,COG2372@2|Bacteria,1N8SS@1224|Proteobacteria,2UFW5@28211|Alphaproteobacteria,4BGCK@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	CopC domain	-	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
MMD2_k127_4484682_27	1229204.AMYY01000015_gene2114	1.906e-46	186.0	COG1276@1|root,COG1276@2|Bacteria,1MXGC@1224|Proteobacteria,2TVGX@28211|Alphaproteobacteria,4BR56@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Copper resistance protein D	ycnJ	-	-	ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	CopC,CopD
MMD2_k127_4484682_12	1380394.JADL01000004_gene5761	2.772e-102	344.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2TTI6@28211|Alphaproteobacteria,2JQC6@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMD2_k127_4484682_51	439235.Dalk_3992	2.006e-07	64.0	2EPTW@1|root,33HED@2|Bacteria,1NK6N@1224|Proteobacteria,4312Q@68525|delta/epsilon subdivisions,2WWWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4484682_11	765910.MARPU_09265	1.246e-110	370.0	COG1524@1|root,COG1524@2|Bacteria,1R2II@1224|Proteobacteria,1RQDZ@1236|Gammaproteobacteria,1X2CP@135613|Chromatiales	135613|Chromatiales	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
MMD2_k127_4484682_21	234267.Acid_7801	4.605e-54	198.0	COG4430@1|root,COG4430@2|Bacteria,3Y5HF@57723|Acidobacteria	57723|Acidobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
MMD2_k127_4484682_15	388413.ALPR1_16933	1.004e-81	276.0	COG3548@1|root,COG3548@2|Bacteria,4NPIF@976|Bacteroidetes,47R96@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
MMD2_k127_4484682_32	644282.Deba_1624	1.117e-37	159.0	COG0546@1|root,COG0546@2|Bacteria,1RKX9@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
MMD2_k127_4484682_17	269084.syc1328_d	5.126e-73	261.0	COG2890@1|root,COG2890@2|Bacteria,1G6DS@1117|Cyanobacteria	1117|Cyanobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMD2_k127_4484682_26	765911.Thivi_3024	6.889e-49	180.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,1S6K5@1236|Gammaproteobacteria,1X0TT@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
MMD2_k127_4484682_30	234267.Acid_6639	7.189e-39	156.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMD2_k127_4484682_40	1535422.ND16A_1911	1.036e-23	111.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMD2_k127_4484682_42	1487953.JMKF01000016_gene2551	1.247e-22	102.0	COG4994@1|root,COG4994@2|Bacteria,1GAWR@1117|Cyanobacteria,1HFH1@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
MMD2_k127_4484682_19	1123393.KB891317_gene2209	3.593e-68	235.0	COG0662@1|root,COG0662@2|Bacteria,1QW6S@1224|Proteobacteria	1224|Proteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD2_k127_4484682_47	1304275.C41B8_00145	2.181e-14	77.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
MMD2_k127_45456_30	1121004.ATVC01000034_gene2252	1.722e-13	70.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_45456_23	314285.KT71_15496	1.79e-37	142.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1J6K6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMD2_k127_45456_0	395493.BegalDRAFT_2469	0.0	1124.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMD2_k127_45456_3	1177154.Y5S_00915	2.212e-212	666.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XH3A@135619|Oceanospirillales	135619|Oceanospirillales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
MMD2_k127_45456_9	998674.ATTE01000001_gene673	3.63e-100	329.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,45ZYA@72273|Thiotrichales	72273|Thiotrichales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMD2_k127_45456_7	187272.Mlg_2289	2.426e-106	360.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1WWKF@135613|Chromatiales	135613|Chromatiales	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
MMD2_k127_45456_13	1123053.AUDG01000004_gene3492	2.51e-86	300.0	COG0747@1|root,COG2982@1|root,COG3637@1|root,COG4547@1|root,COG5184@1|root,COG0747@2|Bacteria,COG2982@2|Bacteria,COG3637@2|Bacteria,COG4547@2|Bacteria,COG5184@2|Bacteria,1QVUE@1224|Proteobacteria,1T2J5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,fn3
MMD2_k127_45456_29	452662.SJA_C1-07730	4.985e-20	94.0	COG2105@1|root,COG2105@2|Bacteria,1N80E@1224|Proteobacteria,2U5YU@28211|Alphaproteobacteria,2K78W@204457|Sphingomonadales	204457|Sphingomonadales	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
MMD2_k127_45456_5	745411.B3C1_01600	1.546e-123	413.0	COG1629@1|root,COG1629@2|Bacteria,1NWW8@1224|Proteobacteria,1RNKZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
MMD2_k127_45456_28	745411.B3C1_01595	8.461e-21	99.0	2EM2B@1|root,33ERT@2|Bacteria,1NNEQ@1224|Proteobacteria,1SIRE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_45456_27	1033802.SSPSH_003756	3.303e-25	118.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,1RQE3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the addition of the first glucose residue to the LPS core	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMD2_k127_45456_36	1223523.H340_18861	0.0003166	44.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMD2_k127_45456_35	1121355.KB903379_gene745	6.165e-06	53.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
MMD2_k127_45456_10	204669.Acid345_4424	2.19e-98	333.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JIT2@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMD2_k127_45456_21	1123354.AUDR01000017_gene83	2.08e-50	185.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1KSZ7@119069|Hydrogenophilales	119069|Hydrogenophilales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
MMD2_k127_45456_19	1384054.N790_06400	3.671e-69	244.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1X5K2@135614|Xanthomonadales	135614|Xanthomonadales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
MMD2_k127_45456_22	1209072.ALBT01000032_gene2033	2.459e-43	164.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1FIIU@10|Cellvibrio	1236|Gammaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase,RyR,TPR_10,TPR_12
MMD2_k127_45456_31	614083.AWQR01000001_gene3031	5.623e-13	77.0	COG0515@1|root,COG0745@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912,ko:K12132	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	HAMP,Pkinase
MMD2_k127_45456_2	243233.MCA2489	2.335e-216	682.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1XETA@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
MMD2_k127_45456_26	1384056.N787_05785	2.992e-25	113.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1X6XU@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane protein, required for colicin V production	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
MMD2_k127_45456_32	519989.ECTPHS_05380	3.187e-12	75.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,1WZEE@135613|Chromatiales	135613|Chromatiales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
MMD2_k127_45456_11	1442599.JAAN01000032_gene1509	9.476e-95	326.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1X32Z@135614|Xanthomonadales	135614|Xanthomonadales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
MMD2_k127_45456_6	765914.ThisiDRAFT_2021	8.865e-119	388.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1WW2U@135613|Chromatiales	135613|Chromatiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMD2_k127_45456_17	765912.Thimo_2651	1.906e-75	262.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1WX2M@135613|Chromatiales	135613|Chromatiales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
MMD2_k127_45456_34	1049564.TevJSym_ar00120	6.768e-07	63.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
MMD2_k127_45456_20	1123257.AUFV01000001_gene1581	9.659e-61	240.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1X4MQ@135614|Xanthomonadales	135614|Xanthomonadales	NU	Tfp pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	TPR_19
MMD2_k127_45456_4	1396858.Q666_14700	3.522e-171	545.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,46517@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518	Chorismate_synt
MMD2_k127_45456_16	396588.Tgr7_1236	2.088e-76	276.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
MMD2_k127_45456_24	713586.KB900536_gene83	4.709e-32	142.0	COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,1WZ46@135613|Chromatiales	135613|Chromatiales	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
MMD2_k127_45456_18	314278.NB231_00900	3.306e-69	246.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1WWNF@135613|Chromatiales	135613|Chromatiales	I	Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
MMD2_k127_45456_14	713586.KB900536_gene85	1.842e-85	295.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1WW5X@135613|Chromatiales	135613|Chromatiales	J	Elongation factor P--(R)-beta-lysine ligase	-	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
MMD2_k127_45456_12	396588.Tgr7_1232	2.238e-94	313.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1WX8C@135613|Chromatiales	135613|Chromatiales	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
MMD2_k127_45456_8	1123256.KB907937_gene1890	1.515e-102	344.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1X3RU@135614|Xanthomonadales	135614|Xanthomonadales	E	lysine 2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
MMD2_k127_45456_15	1122604.JONR01000016_gene4373	2.393e-85	309.0	COG2199@1|root,COG5001@1|root,COG2199@2|Bacteria,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg
MMD2_k127_45456_1	1177179.A11A3_00915	3.495e-307	960.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XH5U@135619|Oceanospirillales	135619|Oceanospirillales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMD2_k127_45456_25	349521.HCH_05734	1.125e-28	115.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1XHCG@135619|Oceanospirillales	135619|Oceanospirillales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMD2_k127_4559472_45	640511.BC1002_4151	3.439e-18	84.0	COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,2VJ02@28216|Betaproteobacteria,1K2C2@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	1.17.99.1	ko:K05797	ko00623,ko01100,ko01120,map00623,map01100,map01120	-	R02675,R11194	RC00769	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMD2_k127_4559472_43	237609.PSAKL28_30920	5.243e-19	94.0	COG2010@1|root,COG2010@2|Bacteria,1PZI6@1224|Proteobacteria,1SI5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMD2_k127_4559472_12	296591.Bpro_3022	3.063e-116	382.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VMVX@28216|Betaproteobacteria,4A9VB@80864|Comamonadaceae	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_4559472_15	234267.Acid_5052	8.494e-103	350.0	COG4948@1|root,COG4948@2|Bacteria,3Y6GX@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMD2_k127_4559472_16	1123023.JIAI01000004_gene8204	5.733e-100	341.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
MMD2_k127_4559472_23	1469245.JFBG01000037_gene1851	5.359e-75	255.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,1S43F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	dehydratase	-	-	4.2.1.56	ko:K18290	ko00660,map00660	-	R02491	RC00730	ko00000,ko00001,ko01000	-	-	-	MaoC_dehydratas
MMD2_k127_4559472_7	1205680.CAKO01000002_gene2170	1.545e-146	475.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2TR7D@28211|Alphaproteobacteria,2JPZ3@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMD2_k127_4559472_6	1458357.BG58_12490	4.807e-150	502.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VMYW@28216|Betaproteobacteria,1K1RG@119060|Burkholderiaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMD2_k127_4559472_1	1205680.CAKO01000002_gene2168	2.755e-202	639.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JR65@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMD2_k127_4559472_27	247633.GP2143_17796	1.652e-49	191.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_11	1007104.SUS17_2461	8.653e-118	392.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales	204457|Sphingomonadales	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
MMD2_k127_4559472_4	1082931.KKY_2582	4.796e-195	627.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
MMD2_k127_4559472_25	1472418.BBJC01000004_gene1788	2.934e-59	222.0	2CBAE@1|root,31814@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_30	83406.HDN1F_22740	4.511e-39	152.0	COG1846@1|root,COG1846@2|Bacteria,1MZY5@1224|Proteobacteria,1SXNP@1236|Gammaproteobacteria,1JAWR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_19	1121403.AUCV01000001_gene999	1.812e-94	323.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42NIC@68525|delta/epsilon subdivisions,2WKV5@28221|Deltaproteobacteria,2MK7B@213118|Desulfobacterales	28221|Deltaproteobacteria	V	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMD2_k127_4559472_3	1177928.TH2_09119	2.198e-197	628.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,2JQ5F@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_4559472_29	1123060.JONP01000061_gene2440	1.861e-43	169.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,2JPRY@204441|Rhodospirillales	204441|Rhodospirillales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
MMD2_k127_4559472_18	1340493.JNIF01000003_gene1475	3.058e-96	330.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_4559472_2	886293.Sinac_1153	5.251e-201	653.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_4559472_28	627192.SLG_31390	1.198e-44	183.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
MMD2_k127_4559472_38	1088721.NSU_4113	1.121e-23	111.0	KOG2391@1|root,3279X@2|Bacteria,1RHDJ@1224|Proteobacteria,2U9SJ@28211|Alphaproteobacteria,2KBN3@204457|Sphingomonadales	204457|Sphingomonadales	O	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_22	682795.AciX8_2650	1.251e-75	269.0	COG0596@1|root,COG0596@2|Bacteria,3Y7W6@57723|Acidobacteria,2JMYQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMD2_k127_4559472_14	502025.Hoch_5169	1.681e-105	351.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
MMD2_k127_4559472_17	75379.Tint_1847	2.201e-97	333.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria,1KK4Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Glucose sorbosone	yliI	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
MMD2_k127_4559472_35	136993.KB900627_gene391	4.498e-28	122.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_41	1165096.ARWF01000001_gene440	6.472e-22	107.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_9	1116369.KB890024_gene2927	9.874e-137	458.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,43HHC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	ABC transporter	hndI	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_4559472_10	335659.S23_17420	2.025e-122	402.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,3JRRG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	transport, permease protein	yadH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMD2_k127_4559472_48	231434.JQJH01000002_gene2359	5.384e-14	86.0	COG0834@1|root,COG3258@1|root,COG0834@2|Bacteria,COG3258@2|Bacteria,1R7UM@1224|Proteobacteria,2VGP6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CET	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,SBP_bac_3
MMD2_k127_4559472_5	935840.JAEQ01000001_gene3216	8.607e-151	501.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
MMD2_k127_4559472_44	247633.GP2143_17791	5.889e-19	96.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_51	555793.WSK_2306	6.541e-08	59.0	2CBFC@1|root,32RYI@2|Bacteria,1N0T4@1224|Proteobacteria,2UEZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_42	1254432.SCE1572_07160	3.768e-19	97.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42VGM@68525|delta/epsilon subdivisions,2WRJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Excinuclease ABC C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
MMD2_k127_4559472_32	1082931.KKY_123	5.303e-33	134.0	2CBAE@1|root,3343U@2|Bacteria,1Q6VU@1224|Proteobacteria,2UJ1K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_46	589873.EP13_13630	3.969e-18	90.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_8	1265505.ATUG01000002_gene1318	4.264e-139	456.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,42U9J@68525|delta/epsilon subdivisions,2WQ39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	ko:K05548,ko:K05819,ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4
MMD2_k127_4559472_39	555793.WSK_2875	7.884e-23	110.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_36	136993.KB900627_gene391	3.684e-26	113.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_40	136993.KB900627_gene392	1.308e-22	109.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_37	1340493.JNIF01000004_gene918	1.055e-24	113.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
MMD2_k127_4559472_0	1007104.SUS17_2413	2.582e-222	710.0	COG4206@1|root,COG4206@2|Bacteria,1N71E@1224|Proteobacteria,2TU7B@28211|Alphaproteobacteria,2K23K@204457|Sphingomonadales	204457|Sphingomonadales	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_4559472_24	1268068.PG5_60570	3.471e-62	216.0	COG3791@1|root,COG3791@2|Bacteria,1RCYS@1224|Proteobacteria,1S3X0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMD2_k127_4559472_13	379066.GAU_1743	8.655e-114	383.0	COG0534@1|root,COG0534@2|Bacteria,1ZUAU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
MMD2_k127_4559472_50	869210.Marky_1416	4.182e-13	77.0	2CP7W@1|root,32MRP@2|Bacteria,1WKBJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4559472_49	762983.HMPREF9444_02038	1.738e-13	78.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HIT
MMD2_k127_4559472_52	1168289.AJKI01000002_gene2477	4.293e-07	59.0	2CJWB@1|root,32P4S@2|Bacteria,4NQ5Z@976|Bacteroidetes,2FXKX@200643|Bacteroidia,3XK2X@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi
MMD2_k127_4559472_33	1209072.ALBT01000025_gene3730	3.157e-32	130.0	COG1725@1|root,COG1725@2|Bacteria,1N23D@1224|Proteobacteria,1S9NK@1236|Gammaproteobacteria,1FHGJ@10|Cellvibrio	1236|Gammaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
MMD2_k127_4559472_20	498211.CJA_0599	1.241e-79	275.0	COG1131@1|root,COG1131@2|Bacteria,1R9P3@1224|Proteobacteria,1S39R@1236|Gammaproteobacteria,1FGNK@10|Cellvibrio	1236|Gammaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_4559472_21	639030.JHVA01000001_gene3382	4.412e-79	282.0	COG1680@1|root,COG1680@2|Bacteria,3Y3WB@57723|Acidobacteria,2JJDH@204432|Acidobacteriia	204432|Acidobacteriia	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
MMD2_k127_4559472_26	1140.Synpcc7942_0085	1.559e-55	205.0	COG0637@1|root,COG0637@2|Bacteria,1G7W5@1117|Cyanobacteria	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMD2_k127_4559472_31	388467.A19Y_2734	1.66e-37	147.0	COG1186@1|root,COG1186@2|Bacteria,1G5Y2@1117|Cyanobacteria,1HB61@1150|Oscillatoriales	1117|Cyanobacteria	J	Protein chain release factor B	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
MMD2_k127_4559472_34	1007104.SUS17_2461	5.551e-32	128.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales	204457|Sphingomonadales	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
MMD2_k127_4561413_20	344747.PM8797T_14941	2.378e-118	406.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
MMD2_k127_4561413_33	266265.Bxe_B2157	8.877e-90	302.0	COG1028@1|root,COG1028@2|Bacteria,1MUWC@1224|Proteobacteria,2W95J@28216|Betaproteobacteria,1K97M@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMD2_k127_4561413_5	234267.Acid_5827	7.394e-232	743.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_4561413_1	1163407.UU7_09370	0.0	1201.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1X5I0@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMD2_k127_4561413_37	983917.RGE_04600	2.28e-86	293.0	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,2VPFP@28216|Betaproteobacteria,1KKPF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	branched-chain amino acid permease (azaleucine resistance)	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
MMD2_k127_4561413_62	864051.BurJ1DRAFT_4294	1.164e-33	150.0	COG4392@1|root,COG4392@2|Bacteria,1N0X2@1224|Proteobacteria,2VTY9@28216|Betaproteobacteria,1KMAM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM branched-chain amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
MMD2_k127_4561413_72	76114.ebA299	8.155e-21	108.0	COG2010@1|root,COG2010@2|Bacteria,1N9X8@1224|Proteobacteria,2W3XT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMD2_k127_4561413_10	1123020.AUIE01000005_gene4241	2.177e-168	554.0	COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,1RNNT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD linked oxidase domain protein	-	-	1.17.99.1	ko:K05797	ko00623,ko01100,ko01120,map00623,map01100,map01120	-	R02675,R11194	RC00769	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMD2_k127_4561413_82	76114.ebA302	2.227e-11	70.0	2F729@1|root,33ZHV@2|Bacteria,1NYCP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_6	1379270.AUXF01000002_gene1148	1.133e-218	701.0	COG4993@1|root,COG4993@2|Bacteria,1ZSSJ@142182|Gemmatimonadetes	2|Bacteria	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
MMD2_k127_4561413_32	172088.AUGA01000023_gene748	7.475e-90	311.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3JRVC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMD2_k127_4561413_16	1123072.AUDH01000007_gene1128	5.171e-138	460.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2JZPA@204441|Rhodospirillales	204441|Rhodospirillales	E	Cobalamin-independent synthase, Catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
MMD2_k127_4561413_54	113395.AXAI01000036_gene354	4.233e-46	175.0	COG0723@1|root,COG0723@2|Bacteria,1R42I@1224|Proteobacteria,2U0F3@28211|Alphaproteobacteria,3JTUR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Rieske [2Fe-2S] domain	MA20_34340	-	-	-	-	-	-	-	-	-	-	-	Rieske
MMD2_k127_4561413_76	398525.KB900701_gene2396	1.087e-16	89.0	2919Q@1|root,32TZW@2|Bacteria,1R3DM@1224|Proteobacteria,2U015@28211|Alphaproteobacteria,3K71Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_68	860228.Ccan_20840	1.733e-24	116.0	COG0671@1|root,COG0671@2|Bacteria,4NMKG@976|Bacteroidetes,1I896@117743|Flavobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
MMD2_k127_4561413_46	517418.Ctha_0220	1.737e-56	211.0	COG0451@1|root,COG0451@2|Bacteria,1FDUB@1090|Chlorobi	1090|Chlorobi	M	3-beta hydroxysteroid dehydrogenase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMD2_k127_4561413_24	483219.LILAB_26910	3.307e-102	349.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_13	944479.JQLX01000011_gene928	1.485e-144	470.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2M6TU@213113|Desulfurellales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	bioF1	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_4561413_44	1266925.JHVX01000002_gene1009	6.767e-60	214.0	COG2345@1|root,COG2345@2|Bacteria,1PW50@1224|Proteobacteria,2VVBN@28216|Betaproteobacteria,37323@32003|Nitrosomonadales	28216|Betaproteobacteria	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_5
MMD2_k127_4561413_43	748280.NH8B_1812	3.862e-60	215.0	2A8Q5@1|root,30XSS@2|Bacteria,1RGZW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_29	1122194.AUHU01000004_gene1416	1.672e-97	325.0	COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,1T268@1236|Gammaproteobacteria,466KQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG0421 Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
MMD2_k127_4561413_67	926554.KI912664_gene1577	2.534e-25	121.0	29XYR@1|root,30JRD@2|Bacteria,1WNBY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
MMD2_k127_4561413_80	1111069.TCCBUS3UF1_11860	1.901e-12	76.0	COG2197@1|root,COG2197@2|Bacteria,1WJUW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
MMD2_k127_4561413_56	192952.MM_1338	2.903e-45	175.0	arCOG07611@1|root,arCOG07611@2157|Archaea,2Y4YS@28890|Euryarchaeota	28890|Euryarchaeota	CM	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11
MMD2_k127_4561413_7	627192.SLG_05610	2.671e-211	694.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2K3KA@204457|Sphingomonadales	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_4561413_4	420662.Mpe_A0363	4.197e-235	744.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,1KK5N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	PQQ enzyme repeat	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
MMD2_k127_4561413_26	1121033.AUCF01000001_gene2206	2.966e-101	336.0	COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,2TWFW@28211|Alphaproteobacteria,2JQWG@204441|Rhodospirillales	204441|Rhodospirillales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMD2_k127_4561413_69	555793.WSK_3236	9.045e-24	106.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_78	1040989.AWZU01000029_gene4334	7.549e-16	88.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,3K390@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_11	1340493.JNIF01000003_gene4160	1.224e-155	508.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
MMD2_k127_4561413_61	1267535.KB906767_gene1286	2.241e-34	141.0	COG2010@1|root,COG2010@2|Bacteria,3Y846@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_4561413_63	1226994.AMZB01000136_gene5216	4.819e-31	130.0	2DBDT@1|root,2Z8NY@2|Bacteria,1N7S2@1224|Proteobacteria,1RTZE@1236|Gammaproteobacteria,1YGWI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_25	864069.MicloDRAFT_00052660	2.669e-101	344.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TSKV@28211|Alphaproteobacteria,1JT9A@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD2_k127_4561413_3	1123269.NX02_05230	8.023e-276	869.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2UQNF@28211|Alphaproteobacteria,2KEEA@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_4561413_39	1198452.Jab_1c23870	2.511e-74	269.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VRVE@28216|Betaproteobacteria,475TS@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD2_k127_4561413_31	1041142.ATTP01000006_gene5614	1.131e-92	324.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,4B89I@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	gst7	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N,GST_N_3
MMD2_k127_4561413_74	555793.WSK_3236	7.297e-20	102.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_48	29581.BW37_00469	3.402e-52	203.0	COG5528@1|root,COG5528@2|Bacteria,1RDUE@1224|Proteobacteria,2VRK8@28216|Betaproteobacteria,474GK@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
MMD2_k127_4561413_18	29581.BW37_00470	2.337e-126	414.0	COG1748@1|root,COG1748@2|Bacteria,1P35E@1224|Proteobacteria,2VPXY@28216|Betaproteobacteria,476ZE@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
MMD2_k127_4561413_60	627192.SLG_25160	6.733e-37	160.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria,2KE01@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_40	234267.Acid_6895	6.076e-68	238.0	COG0745@1|root,COG0745@2|Bacteria,3Y4J9@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_4561413_22	234267.Acid_6896	2.96e-113	390.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,3Y97Y@57723|Acidobacteria	57723|Acidobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMD2_k127_4561413_0	1380355.JNIJ01000040_gene5198	0.0	1287.0	COG0841@1|root,COG0841@2|Bacteria,1R93M@1224|Proteobacteria,2UP7I@28211|Alphaproteobacteria,3K354@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMD2_k127_4561413_59	172088.AUGA01000002_gene6136	3.23e-37	164.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2U105@28211|Alphaproteobacteria,3JV31@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Biotin-lipoyl like	ragD	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMD2_k127_4561413_49	243090.RB183	9.589e-52	201.0	COG1538@1|root,COG1538@2|Bacteria,2IWU5@203682|Planctomycetes	203682|Planctomycetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD2_k127_4561413_70	555793.WSK_2875	1.336e-23	109.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_83	715451.ambt_12010	1.446e-09	71.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_30	483219.LILAB_34455	1.365e-93	329.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
MMD2_k127_4561413_86	1343158.SACS_1421	6.916e-06	54.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2JS47@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
MMD2_k127_4561413_15	76114.ebA5068	1.616e-142	459.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,2KV68@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the radical SAM superfamily. RlmN family	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
MMD2_k127_4561413_50	365046.Rta_13530	3.601e-50	194.0	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,2VV1E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
MMD2_k127_4561413_12	1458427.BAWN01000013_gene757	3.683e-148	485.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,4AAFR@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART transcription factor jumonji jmjC	ycfD	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
MMD2_k127_4561413_9	717774.Marme_2942	3.025e-188	609.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMD2_k127_4561413_55	251221.35212002	1.307e-45	167.0	COG0640@1|root,COG0640@2|Bacteria,1GFKP@1117|Cyanobacteria	1117|Cyanobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMD2_k127_4561413_47	319003.Bra1253DRAFT_06407	5.006e-54	196.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria,3JSA3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
MMD2_k127_4561413_51	379066.GAU_3468	1.022e-49	183.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	AHSA1
MMD2_k127_4561413_35	1353531.AZNX01000010_gene1071	1.337e-88	306.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,4BA0J@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
MMD2_k127_4561413_52	240016.ABIZ01000001_gene965	4.425e-47	180.0	COG0760@1|root,COG0760@2|Bacteria,46VUP@74201|Verrucomicrobia,2IVK4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
MMD2_k127_4561413_17	1121033.AUCF01000001_gene2554	1.218e-127	425.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2JQVG@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMD2_k127_4561413_85	1442599.JAAN01000036_gene551	9.386e-07	59.0	2EIBG@1|root,33C2W@2|Bacteria,1NM4U@1224|Proteobacteria,1SIM3@1236|Gammaproteobacteria,1X72G@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_27	349163.Acry_0450	5.524e-101	332.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,2JQ2Y@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_4561413_19	1249627.D779_1262	1.043e-125	417.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,1RQPH@1236|Gammaproteobacteria,1WX21@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMD2_k127_4561413_45	1123393.KB891327_gene304	5.255e-58	213.0	COG3663@1|root,COG3663@2|Bacteria,1REPV@1224|Proteobacteria,2VRAT@28216|Betaproteobacteria,1KSZ9@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
MMD2_k127_4561413_41	519989.ECTPHS_09732	3.525e-61	220.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1WWMW@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
MMD2_k127_4561413_23	1123279.ATUS01000001_gene2455	2.11e-103	344.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RZ5E@1236|Gammaproteobacteria,1J8I4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	ApbE family	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMD2_k127_4561413_34	1123279.ATUS01000001_gene2453	2.982e-89	314.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,1JC29@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
MMD2_k127_4561413_71	1122603.ATVI01000005_gene3689	4.012e-23	100.0	2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,1X8IM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
MMD2_k127_4561413_57	3988.XP_002536756.1	2.246e-40	155.0	2BGJX@1|root,2S19K@2759|Eukaryota,380MM@33090|Viridiplantae	33090|Viridiplantae	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
MMD2_k127_4561413_8	335543.Sfum_1859	9.103e-208	669.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,42Q50@68525|delta/epsilon subdivisions,2WJN7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_66	1121920.AUAU01000010_gene27	1.714e-27	129.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
MMD2_k127_4561413_58	1123073.KB899242_gene1160	5.935e-39	152.0	COG1876@1|root,COG1876@2|Bacteria,1N1CQ@1224|Proteobacteria,1SASN@1236|Gammaproteobacteria,1X577@135614|Xanthomonadales	135614|Xanthomonadales	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
MMD2_k127_4561413_28	1384054.N790_12970	3.264e-100	348.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
MMD2_k127_4561413_53	1541065.JRFE01000003_gene5429	2.995e-46	173.0	COG0625@1|root,COG0625@2|Bacteria,1G5YJ@1117|Cyanobacteria,3VJXZ@52604|Pleurocapsales	1117|Cyanobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
MMD2_k127_4561413_73	351348.Maqu_0685	2.254e-20	104.0	COG0457@1|root,COG0457@2|Bacteria,1N8R8@1224|Proteobacteria,1SITK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2,TPR_16
MMD2_k127_4561413_87	225937.HP15_344	0.0008015	48.0	2AYIH@1|root,31QN9@2|Bacteria,1QN8E@1224|Proteobacteria,1SH36@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4561413_81	1415780.JPOG01000001_gene815	2.862e-12	76.0	COG5662@1|root,COG5662@2|Bacteria,1NGBV@1224|Proteobacteria,1SGXN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMD2_k127_4561413_65	1396858.Q666_15390	4.679e-28	123.0	COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria,468VM@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_4561413_64	1380387.JADM01000023_gene1845	5.289e-29	130.0	2DKFZ@1|root,309D6@2|Bacteria,1REQQ@1224|Proteobacteria,1S796@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
MMD2_k127_4561413_2	187272.Mlg_0941	1.476e-282	879.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1WW7K@135613|Chromatiales	135613|Chromatiales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
MMD2_k127_4561413_21	663610.JQKO01000016_gene1628	2.754e-115	378.0	COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,2VEUG@28211|Alphaproteobacteria,3NB3G@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD2_k127_4561413_36	614083.AWQR01000038_gene1385	2.468e-88	295.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2VKQ8@28216|Betaproteobacteria,4AFYK@80864|Comamonadaceae	28216|Betaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
MMD2_k127_4561413_42	1304877.KI519399_gene4750	1.975e-60	225.0	COG3964@1|root,COG3964@2|Bacteria,1MVC7@1224|Proteobacteria,2TSUD@28211|Alphaproteobacteria,3JSBJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
MMD2_k127_4561413_14	991905.SL003B_1085	6.153e-143	464.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,4BQ89@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
MMD2_k127_4561413_38	991905.SL003B_1084	3.15e-76	263.0	COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,2TTKB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMD2_k127_4594674_19	1415780.JPOG01000001_gene2985	1.03e-44	186.0	COG2816@1|root,COG2816@2|Bacteria,1REUJ@1224|Proteobacteria,1RXWP@1236|Gammaproteobacteria,1X7AX@135614|Xanthomonadales	135614|Xanthomonadales	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF442,NUDIX
MMD2_k127_4594674_6	1038860.AXAP01000018_gene3108	1.301e-149	494.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_4594674_24	136993.KB900627_gene392	2.68e-22	108.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4594674_26	136993.KB900627_gene391	5.618e-16	82.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4594674_13	536019.Mesop_0598	3.403e-87	296.0	COG2162@1|root,COG2162@2|Bacteria,1RDF3@1224|Proteobacteria,2U7QG@28211|Alphaproteobacteria,43MTI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Belongs to the arylamine N-acetyltransferase family	nat	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
MMD2_k127_4594674_18	446466.Cfla_0507	5.495e-46	177.0	COG0500@1|root,COG2226@2|Bacteria,2GJUF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMD2_k127_4594674_2	1385511.N783_00010	1.097e-217	698.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli	91061|Bacilli	CG	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_4594674_3	566466.NOR53_2004	1.324e-170	540.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	fldW	-	4.1.1.45,4.2.1.83	ko:K03392,ko:K10220	ko00362,ko00380,ko01100,ko01120,map00362,map00380,map01100,map01120	M00038	R04323,R04478	RC00498,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
MMD2_k127_4594674_14	1123073.KB899242_gene1540	1.138e-73	253.0	COG1670@1|root,COG1670@2|Bacteria,1RD77@1224|Proteobacteria,1SZ7D@1236|Gammaproteobacteria,1X62B@135614|Xanthomonadales	135614|Xanthomonadales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMD2_k127_4594674_15	627192.SLG_31380	9.558e-71	248.0	COG4886@1|root,COG4886@2|Bacteria,1N4KB@1224|Proteobacteria	1224|Proteobacteria	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
MMD2_k127_4594674_17	1458357.BG58_28305	1.633e-50	199.0	COG3115@1|root,COG3115@2|Bacteria,1QVM5@1224|Proteobacteria,2WI17@28216|Betaproteobacteria,1KG8X@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
MMD2_k127_4594674_9	1267535.KB906767_gene1576	3.671e-97	330.0	COG2010@1|root,COG2010@2|Bacteria,3Y7CN@57723|Acidobacteria,2JK7I@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMD2_k127_4594674_4	1267535.KB906767_gene1575	1.39e-167	542.0	COG2133@1|root,COG2133@2|Bacteria,3Y6R6@57723|Acidobacteria,2JMHE@204432|Acidobacteriia	204432|Acidobacteriia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4594674_21	864051.BurJ1DRAFT_1919	8.649e-34	138.0	COG4922@1|root,COG4922@2|Bacteria,1MYTU@1224|Proteobacteria,2WG68@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4594674_23	1340493.JNIF01000003_gene2122	1.12e-23	108.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4594674_22	1340493.JNIF01000003_gene2123	4.9e-25	119.0	28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4594674_16	1500890.JQNL01000001_gene2465	7.195e-63	228.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1X3W9@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMD2_k127_4594674_12	1000565.METUNv1_02055	6.419e-90	307.0	COG1215@1|root,COG1215@2|Bacteria,1QTWU@1224|Proteobacteria,2WGWG@28216|Betaproteobacteria,2KZQC@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD2_k127_4594674_10	243365.CV_1161	4.099e-96	331.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VHVR@28216|Betaproteobacteria,2KQNQ@206351|Neisseriales	206351|Neisseriales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT
MMD2_k127_4594674_25	279714.FuraDRAFT_1102	4.706e-21	105.0	COG2246@1|root,COG2246@2|Bacteria,1N6WN@1224|Proteobacteria,2VW0C@28216|Betaproteobacteria,2KS64@206351|Neisseriales	206351|Neisseriales	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
MMD2_k127_4594674_5	1226994.AMZB01000070_gene2377	1.244e-149	483.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1YF8F@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	arnB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363	2.6.1.87	ko:K07806	ko00520,ko01503,ko02020,map00520,map01503,map02020	M00721,M00761	R07659	RC00006,RC01514	ko00000,ko00001,ko00002,ko01000,ko01005,ko01007	-	-	iSFxv_1172.SFxv_2574	DegT_DnrJ_EryC1
MMD2_k127_4594674_8	1121396.KB893024_gene3900	5.314e-105	369.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2WJV8@28221|Deltaproteobacteria,2MN5W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	arnC	-	2.4.2.53	ko:K10012,ko:K20534	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8,4.D.2.1.9	GT2	-	Glycos_transf_2
MMD2_k127_4594674_20	909663.KI867150_gene2393	1.679e-36	160.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase, family 39	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
MMD2_k127_4594674_1	558884.JRGM01000136_gene1091	4.355e-295	919.0	COG0223@1|root,COG0451@1|root,COG0223@2|Bacteria,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,1Y4ZZ@135624|Aeromonadales	135624|Aeromonadales	I	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	arnA	-	1.1.1.305,2.1.2.13	ko:K10011	ko00520,ko01503,map00520,map01503	M00721,M00761	R07658,R07660	RC00026,RC01575,RC01812	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,Formyl_trans_C,Formyl_trans_N
MMD2_k127_4594674_11	95619.PM1_0205975	1.87e-95	332.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,1RQ0R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	arnD	GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896	-	ko:K13014	ko00520,ko01503,map00520,map01503	M00721,M00761	R07662	RC00323,RC01575	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iB21_1397.B21_02141,iBWG_1329.BWG_2029,iEC042_1314.EC042_2499,iECBD_1354.ECBD_1403,iECB_1328.ECB_02182,iECDH10B_1368.ECDH10B_2416,iECDH1ME8569_1439.ECDH1ME8569_2192,iECD_1391.ECD_02182,iECO103_1326.ECO103_2722,iECO111_1330.ECO111_3006,iECO26_1355.ECO26_3246,iECUMN_1333.ECUMN_2597,iECW_1372.ECW_m2447,iEKO11_1354.EKO11_1508,iETEC_1333.ETEC_2390,iEcDH1_1363.EcDH1_1402,iEcHS_1320.EcHS_A2401,iEcolC_1368.EcolC_1393,iJO1366.b2256,iSFV_1184.SFV_2326,iSSON_1240.SSON_2317,iUMNK88_1353.UMNK88_2808,iWFL_1372.ECW_m2447,iY75_1357.Y75_RS11830	Polysacc_deac_1
MMD2_k127_4594674_7	1121396.KB893024_gene3903	1.072e-107	369.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,2MM2H@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
MMD2_k127_4594674_29	243231.GSU1152	4.384e-06	53.0	COG2510@1|root,COG2510@2|Bacteria,1NDZV@1224|Proteobacteria,42V6K@68525|delta/epsilon subdivisions,2WRTX@28221|Deltaproteobacteria,43UXY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD2_k127_4594674_28	1524467.IV04_08735	3.84e-11	72.0	COG2076@1|root,COG2076@2|Bacteria,1N7ZX@1224|Proteobacteria,1SCDW@1236|Gammaproteobacteria,403HI@613|Serratia	1236|Gammaproteobacteria	U	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane	arnF	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K12963	ko01503,map01503	M00721	-	-	ko00000,ko00001,ko00002,ko01005	2.A.7	-	iECUMN_1333.ECUMN_2601,iSF_1195.SF2337,iS_1188.S2471	EamA,Multi_Drug_Res
MMD2_k127_4594674_0	420324.KI911999_gene8064	4.506e-298	932.0	28JZZ@1|root,2Z9PZ@2|Bacteria,1N3C6@1224|Proteobacteria,2TSCX@28211|Alphaproteobacteria,1JTZB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4594674_27	715451.ambt_12010	1.222e-15	90.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4626016_33	555793.WSK_1442	1.18e-09	69.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4626016_27	1210884.HG799466_gene12519	1.144e-34	144.0	COG2819@1|root,COG2819@2|Bacteria,2J320@203682|Planctomycetes	203682|Planctomycetes	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
MMD2_k127_4626016_32	682795.AciX8_3942	6.44e-19	94.0	COG5395@1|root,COG5395@2|Bacteria,3Y9FU@57723|Acidobacteria,2JP81@204432|Acidobacteriia	204432|Acidobacteriia	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
MMD2_k127_4626016_23	1469245.JFBG01000024_gene1212	1.079e-47	179.0	COG4106@1|root,COG4106@2|Bacteria,1QZC8@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMD2_k127_4626016_37	1348114.OM33_01745	0.0001053	53.0	COG0810@1|root,COG0810@2|Bacteria,1RGHP@1224|Proteobacteria,1S54W@1236|Gammaproteobacteria,2Q2E5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
MMD2_k127_4626016_24	251229.Chro_3389	2.634e-41	162.0	2CYFR@1|root,32T44@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
MMD2_k127_4626016_6	653045.Strvi_6071	5.078e-139	459.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMD2_k127_4626016_36	1502852.FG94_01117	2.238e-05	55.0	2DWII@1|root,340HA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4626016_30	1234364.AMSF01000033_gene446	3.651e-25	117.0	arCOG07533@1|root,2ZF5I@2|Bacteria,1RB8D@1224|Proteobacteria,1SBRH@1236|Gammaproteobacteria,1X79G@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
MMD2_k127_4626016_9	234267.Acid_2447	1.705e-120	400.0	COG3391@1|root,COG3391@2|Bacteria,3Y8A0@57723|Acidobacteria	57723|Acidobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD2_k127_4626016_28	1123053.AUDG01000004_gene3541	6.851e-31	141.0	2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2799
MMD2_k127_4626016_14	1283299.AUKG01000003_gene666	5.614e-101	340.0	COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	efe	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
MMD2_k127_4626016_29	1038860.AXAP01000042_gene90	4.501e-28	117.0	COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,2U65K@28211|Alphaproteobacteria,3JY8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_4626016_15	936455.KI421499_gene87	5.109e-100	334.0	COG2084@1|root,COG2084@2|Bacteria,1MWR4@1224|Proteobacteria,2U157@28211|Alphaproteobacteria,3JRTW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	MA20_14105	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMD2_k127_4626016_11	935840.JAEQ01000020_gene2307	2.478e-110	372.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMD2_k127_4626016_35	266779.Meso_2900	3.481e-07	59.0	COG3909@1|root,COG3909@2|Bacteria	2|Bacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
MMD2_k127_4626016_19	1126627.BAWE01000005_gene6046	5.126e-57	203.0	COG0599@1|root,COG0599@2|Bacteria,1RDSG@1224|Proteobacteria,2U72V@28211|Alphaproteobacteria,3JY1A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	MA20_14140	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMD2_k127_4626016_5	1242864.D187_010380	1.536e-148	477.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42UHA@68525|delta/epsilon subdivisions,2WQA0@28221|Deltaproteobacteria,2YUHZ@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMD2_k127_4626016_25	864051.BurJ1DRAFT_1919	3.845e-39	152.0	COG4922@1|root,COG4922@2|Bacteria,1MYTU@1224|Proteobacteria,2WG68@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4626016_0	1211115.ALIQ01000198_gene446	3.872e-233	731.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3NC6F@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMD2_k127_4626016_26	627192.SLG_33430	1.224e-37	146.0	2CHCP@1|root,32S5R@2|Bacteria,1MZ97@1224|Proteobacteria,2U9KI@28211|Alphaproteobacteria,2K5WE@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
MMD2_k127_4626016_21	749927.AMED_0325	1.185e-53	194.0	COG0645@1|root,COG0645@2|Bacteria,2I4UW@201174|Actinobacteria,4E5YW@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,AAA_33,CPT
MMD2_k127_4626016_8	344747.PM8797T_02884	1.035e-124	409.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMD2_k127_4626016_12	1211115.ALIQ01000198_gene447	1.945e-108	357.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,2TRG9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_4626016_16	1380391.JIAS01000001_gene2593	2.41e-87	306.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TR5S@28211|Alphaproteobacteria,2JS6W@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
MMD2_k127_4626016_1	1254432.SCE1572_44265	1.884e-222	706.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2YU3K@29|Myxococcales	28221|Deltaproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
MMD2_k127_4626016_13	1163617.SCD_n00973	3.742e-104	379.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD2_k127_4626016_34	1123399.AQVE01000028_gene171	2.038e-07	65.0	COG1864@1|root,COG3291@1|root,COG3391@1|root,COG1864@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,1R5MU@1224|Proteobacteria,1RZ6G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD,REJ
MMD2_k127_4626016_17	1278309.KB907099_gene2927	1.515e-79	295.0	COG4105@1|root,COG4571@1|root,COG4105@2|Bacteria,COG4571@2|Bacteria,1QWIQ@1224|Proteobacteria,1S1BG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4626016_18	1535422.ND16A_1223	5.351e-74	257.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,1RQ6X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4626016_3	1049564.TevJSym_ar00360	1.316e-168	545.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,1T3FX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD2_k127_4626016_22	1245469.S58_30890	6.389e-48	186.0	COG1142@1|root,COG1142@2|Bacteria,1RIXA@1224|Proteobacteria,2UDYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4626016_38	266264.Rmet_4054	0.0002157	50.0	COG3088@1|root,COG4235@1|root,COG3088@2|Bacteria,COG4235@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria	28216|Betaproteobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH,TPR_16
MMD2_k127_4626016_4	1049564.TevJSym_ar00380	2.047e-161	519.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1QYEW@1224|Proteobacteria,1T3PI@1236|Gammaproteobacteria,1JAK0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Pyr_redox_3
MMD2_k127_4626016_10	234267.Acid_7430	5.442e-119	392.0	COG0604@1|root,COG0604@2|Bacteria,3Y35U@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_4626016_2	240015.ACP_0313	3.503e-204	642.0	COG3508@1|root,COG3508@2|Bacteria,3Y38R@57723|Acidobacteria,2JHM4@204432|Acidobacteriia	204432|Acidobacteriia	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
MMD2_k127_4626016_20	759362.KVU_2272	2.113e-54	203.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2TSZM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD2_k127_4626016_31	519989.ECTPHS_01569	1.357e-21	102.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1WWUD@135613|Chromatiales	135613|Chromatiales	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
MMD2_k127_4646457_2	388413.ALPR1_05685	1.032e-61	220.0	COG4117@1|root,COG4117@2|Bacteria,4NG6M@976|Bacteroidetes,47NBT@768503|Cytophagia	976|Bacteroidetes	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB,Oxidored_molyb
MMD2_k127_4646457_1	388413.ALPR1_05690	7.918e-87	293.0	COG2041@1|root,COG2041@2|Bacteria,4NK0M@976|Bacteroidetes,47P5T@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
MMD2_k127_4646457_3	1382359.JIAL01000001_gene1134	3.774e-28	130.0	COG3182@1|root,COG3182@2|Bacteria,3Y2R7@57723|Acidobacteria,2JIBB@204432|Acidobacteriia	204432|Acidobacteriia	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
MMD2_k127_4646457_0	1144305.PMI02_01867	4.224e-117	393.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VFU5@28211|Alphaproteobacteria,2KDZN@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_4670258_8	543728.Vapar_0124	3.661e-68	253.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2VIK2@28216|Betaproteobacteria,4ACVQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMD2_k127_4670258_9	247633.GP2143_17796	3.615e-61	225.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4670258_0	384676.PSEEN3176	5.446e-245	786.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	ybiT	GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
MMD2_k127_4670258_13	1229485.AMYV01000057_gene2029	2.097e-12	72.0	COG2246@1|root,COG2246@2|Bacteria,1PHDG@1224|Proteobacteria,1RW0H@1236|Gammaproteobacteria,1JBN7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
MMD2_k127_4670258_6	1267534.KB906756_gene691	7.88e-88	313.0	COG1735@1|root,COG1735@2|Bacteria,3Y646@57723|Acidobacteria	57723|Acidobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4670258_1	1122604.JONR01000010_gene3999	2.986e-170	556.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1X4NS@135614|Xanthomonadales	135614|Xanthomonadales	M	Lytic murein transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
MMD2_k127_4670258_2	1380394.JADL01000013_gene573	2.196e-169	564.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2JPB3@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
MMD2_k127_4670258_10	1192868.CAIU01000027_gene3703	3.109e-53	198.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U7NJ@28211|Alphaproteobacteria,43R40@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMD2_k127_4670258_3	485918.Cpin_2522	6.144e-123	404.0	COG0500@1|root,COG2226@2|Bacteria,4NFRD@976|Bacteroidetes,1IVKT@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMD2_k127_4670258_5	1123256.KB907931_gene2764	2.012e-92	317.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,1RPZF@1236|Gammaproteobacteria,1X3MX@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_4670258_7	1123257.AUFV01000005_gene1320	7.518e-86	297.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,1RRH7@1236|Gammaproteobacteria,1X430@135614|Xanthomonadales	135614|Xanthomonadales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_4670258_16	1004785.AMBLS11_16885	1.567e-06	60.0	COG0810@1|root,COG0810@2|Bacteria,1RGHP@1224|Proteobacteria,1S54W@1236|Gammaproteobacteria,46ACR@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
MMD2_k127_4670258_4	627192.SLG_28840	8.453e-110	366.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U4X1@28211|Alphaproteobacteria,2K9G4@204457|Sphingomonadales	204457|Sphingomonadales	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
MMD2_k127_4670258_15	247633.GP2143_15126	4.238e-07	58.0	COG3012@1|root,COG3012@2|Bacteria,1PQ4S@1224|Proteobacteria,1TAC0@1236|Gammaproteobacteria,1JBGW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family (UPF0149)	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C,UPF0149
MMD2_k127_4672753_12	1249627.D779_1070	4.708e-23	115.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1WY2S@135613|Chromatiales	135613|Chromatiales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
MMD2_k127_4672753_0	396588.Tgr7_0191	0.0	1070.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
MMD2_k127_4672753_9	754476.Q7A_246	2.749e-44	168.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,4612G@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
MMD2_k127_4672753_5	765912.Thimo_1249	8.156e-95	323.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1WWKX@135613|Chromatiales	135613|Chromatiales	LU	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
MMD2_k127_4672753_6	754477.Q7C_1938	3.621e-92	316.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,461TR@72273|Thiotrichales	72273|Thiotrichales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
MMD2_k127_4672753_7	1158762.KB898045_gene418	1.043e-60	215.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1WXF4@135613|Chromatiales	135613|Chromatiales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
MMD2_k127_4672753_4	765912.Thimo_1246	9.392e-103	343.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1WWQE@135613|Chromatiales	135613|Chromatiales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
MMD2_k127_4672753_3	187272.Mlg_2626	1.464e-115	387.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1WVWG@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
MMD2_k127_4672753_10	314278.NB231_11619	3.248e-39	156.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,1WYAZ@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
MMD2_k127_4672753_1	187272.Mlg_2624	2.168e-192	624.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
MMD2_k127_4672753_2	1123073.KB899241_gene2690	3.588e-123	418.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1X5SE@135614|Xanthomonadales	135614|Xanthomonadales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD2_k127_4672753_11	519989.ECTPHS_12622	8.204e-37	147.0	COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SWTF@1236|Gammaproteobacteria,1WZTX@135613|Chromatiales	135613|Chromatiales	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
MMD2_k127_4672753_8	187272.Mlg_2496	7.233e-57	203.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales	135613|Chromatiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
MMD2_k127_4749995_2	95619.PM1_0213450	1.879e-58	208.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,1S6J5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
MMD2_k127_4749995_0	869210.Marky_1349	9.219e-151	493.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1WJ1X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
MMD2_k127_4749995_3	1122603.ATVI01000005_gene3042	2.841e-43	169.0	COG0668@1|root,COG0668@2|Bacteria,1N4UN@1224|Proteobacteria,1T9TX@1236|Gammaproteobacteria,1XBUR@135614|Xanthomonadales	135614|Xanthomonadales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
MMD2_k127_4749995_4	1122603.ATVI01000005_gene3041	1.045e-26	126.0	COG2239@1|root,COG2239@2|Bacteria,1NNAQ@1224|Proteobacteria,1SHM4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
MMD2_k127_4749995_1	1415778.JQMM01000001_gene1963	8.121e-118	395.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1J4XQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
MMD2_k127_4764924_3	215803.DB30_2951	1.468e-08	60.0	COG0016@1|root,COG0016@2|Bacteria,1R9QP@1224|Proteobacteria,4378A@68525|delta/epsilon subdivisions,2X3XB@28221|Deltaproteobacteria,2YXFM@29|Myxococcales	28221|Deltaproteobacteria	J	Ferredoxin-fold anticodon binding domain	-	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	FDX-ACB,tRNA-synt_2d
MMD2_k127_4764924_0	1379270.AUXF01000007_gene993	4.542e-89	306.0	COG3391@1|root,COG3391@2|Bacteria,1ZSNC@142182|Gemmatimonadetes	2|Bacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,FlgD_ig,NHL
MMD2_k127_4764924_1	1101195.Meth11DRAFT_1463	1.357e-25	117.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4764924_4	1280954.HPO_17721	5.08e-06	54.0	COG3152@1|root,COG3152@2|Bacteria,1NDNG@1224|Proteobacteria,2TT9F@28211|Alphaproteobacteria,43YRM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
MMD2_k127_4764924_2	935261.JAGL01000002_gene1474	2.403e-13	80.0	2A8ZW@1|root,30Y3S@2|Bacteria,1P55Z@1224|Proteobacteria,2UYJ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4774660_1	52598.EE36_14362	9.357e-39	153.0	COG0685@1|root,COG0685@2|Bacteria,1MVWT@1224|Proteobacteria,2TTSF@28211|Alphaproteobacteria,3ZVTJ@60136|Sulfitobacter	28211|Alphaproteobacteria	E	COG0685 5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
MMD2_k127_4774660_0	991905.SL003B_2672	7.675e-160	517.0	COG0742@1|root,COG0742@2|Bacteria,1MW6A@1224|Proteobacteria,2TQNI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ribosomal rna small subunit methyltransferase	MA20_07810	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4774660_2	1279017.AQYJ01000028_gene2525	7.994e-34	150.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_4774660_3	1120933.ATUY01000002_gene45	2.799e-09	60.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,4D3HF@85005|Actinomycetales	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE2	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMD2_k127_4783292_5	1000565.METUNv1_03838	9.8e-07	53.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,2KU89@206389|Rhodocyclales	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
MMD2_k127_4783292_4	1440052.EAKF1_ch1016	4.723e-14	87.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,3XQ1J@561|Escherichia	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
MMD2_k127_4783292_2	550540.Fbal_1759	6.878e-77	259.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,1S25G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMD2_k127_4783292_1	1249627.D779_3023	3.261e-181	578.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales	135613|Chromatiales	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
MMD2_k127_4783292_3	713586.KB900536_gene2900	1.491e-65	229.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria,1WX78@135613|Chromatiales	135613|Chromatiales	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
MMD2_k127_4783292_0	396588.Tgr7_2123	2.29e-297	924.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMD2_k127_4804105_4	1380391.JIAS01000017_gene634	2.101e-59	216.0	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,2TSPG@28211|Alphaproteobacteria,2JRPX@204441|Rhodospirillales	204441|Rhodospirillales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
MMD2_k127_4804105_7	1379698.RBG1_1C00001G0251	1.587e-19	97.0	2DEGI@1|root,2ZMXA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4804105_3	1255043.TVNIR_3549	2.046e-87	293.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1WWXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
MMD2_k127_4804105_2	395493.BegalDRAFT_3434	1.732e-133	436.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
MMD2_k127_4804105_6	395493.BegalDRAFT_3435	1.268e-42	157.0	COG3288@1|root,COG3288@2|Bacteria,1N0TD@1224|Proteobacteria,1SA8D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NADP transhydrogenase	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
MMD2_k127_4804105_0	395493.BegalDRAFT_3436	2.82e-176	583.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
MMD2_k127_4804105_8	1117647.M5M_03060	1.036e-16	89.0	2BUQS@1|root,32Q1V@2|Bacteria,1PJQ8@1224|Proteobacteria,1T6IW@1236|Gammaproteobacteria,1J77Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
MMD2_k127_4804105_9	1049564.TevJSym_am00570	1.39e-05	52.0	2DU53@1|root,33NYX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4804105_5	243231.GSU0721	1.996e-46	176.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,430GK@68525|delta/epsilon subdivisions,2WVVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-70, region 4	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
MMD2_k127_4804105_1	765912.Thimo_2397	1.076e-164	537.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales	135613|Chromatiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
MMD2_k127_4807203_13	861299.J421_1109	1.243e-66	233.0	COG1132@1|root,COG1132@2|Bacteria,1ZUSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
MMD2_k127_4807203_5	509190.Cseg_0103	7.523e-143	486.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,2KF5V@204458|Caulobacterales	204458|Caulobacterales	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMD2_k127_4807203_12	666685.R2APBS1_0264	1.214e-66	235.0	28ME7@1|root,2ZARX@2|Bacteria,1R90X@1224|Proteobacteria,1SC25@1236|Gammaproteobacteria,1XAFT@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
MMD2_k127_4807203_1	1095769.CAHF01000023_gene501	3.896e-183	589.0	COG2203@1|root,COG2203@2|Bacteria,1PP8V@1224|Proteobacteria,2VKHH@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
MMD2_k127_4807203_19	62928.azo1537	2.617e-34	146.0	COG3576@1|root,COG3576@2|Bacteria,1N8Z5@1224|Proteobacteria,2VVVW@28216|Betaproteobacteria,2KX6P@206389|Rhodocyclales	206389|Rhodocyclales	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4807203_16	670307.HYPDE_23308	1.863e-50	196.0	COG0778@1|root,COG0778@2|Bacteria,1RDJ6@1224|Proteobacteria,2U44Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD2_k127_4807203_3	1265313.HRUBRA_01849	2.8e-168	554.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ_2
MMD2_k127_4807203_29	869210.Marky_0880	1.48e-05	54.0	COG2335@1|root,COG2335@2|Bacteria,1WNHM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	CHRD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
MMD2_k127_4807203_10	1123257.AUFV01000005_gene1409	1.178e-76	264.0	COG1028@1|root,COG1028@2|Bacteria,1N8G3@1224|Proteobacteria,1RZ80@1236|Gammaproteobacteria,1X66T@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMD2_k127_4807203_17	666685.R2APBS1_2870	1.968e-36	156.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1S2ZF@1236|Gammaproteobacteria,1X9DG@135614|Xanthomonadales	135614|Xanthomonadales	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMD2_k127_4807203_24	136993.KB900627_gene392	6.643e-19	101.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4807203_26	555793.WSK_2874	4.343e-12	73.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4807203_21	195250.CM001776_gene1121	2.067e-28	128.0	COG0491@1|root,COG0491@2|Bacteria,1G400@1117|Cyanobacteria,1H175@1129|Synechococcus	1117|Cyanobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_4807203_18	38033.XP_001226990.1	1.69e-34	153.0	COG0666@1|root,COG3250@1|root,KOG0504@2759|Eukaryota,KOG2024@2759|Eukaryota,38HKN@33154|Opisthokonta,3NWJH@4751|Fungi,3QP5T@4890|Ascomycota,214DX@147550|Sordariomycetes,3U7AJ@5139|Sordariales,3HFEP@35718|Chaetomiaceae	4751|Fungi	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
MMD2_k127_4807203_9	627192.SLG_31400	7.679e-89	308.0	COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_4807203_2	886293.Sinac_1153	1.312e-171	568.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_4807203_27	1117647.M5M_04580	6.804e-12	78.0	2C612@1|root,32RGH@2|Bacteria,1RGYZ@1224|Proteobacteria,1S8MM@1236|Gammaproteobacteria,1J6RN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4807203_0	322710.Avin_25380	2.107e-232	745.0	COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,1SISW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3376)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3376,Patatin
MMD2_k127_4807203_23	1448139.AI20_12325	4.451e-27	119.0	COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,1S4XS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4807203_14	234267.Acid_3398	4.639e-60	222.0	COG1228@1|root,COG1228@2|Bacteria,3Y4IP@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD2_k127_4807203_22	1120950.KB892767_gene5169	2.341e-27	116.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria,4DTC9@85009|Propionibacteriales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
MMD2_k127_4807203_4	627192.SLG_05610	4.657e-153	524.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2K3KA@204457|Sphingomonadales	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_4807203_11	156889.Mmc1_3311	3.167e-74	267.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria	1224|Proteobacteria	M	COG0438 Glycosyltransferase	tuaH	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
MMD2_k127_4807203_20	1280948.HY36_14660	6.068e-34	145.0	COG1215@1|root,COG1215@2|Bacteria,1R4P3@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
MMD2_k127_4807203_8	519989.ECTPHS_06477	3.273e-115	389.0	COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,1SYZR@1236|Gammaproteobacteria,1X2JN@135613|Chromatiales	135613|Chromatiales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
MMD2_k127_4807203_28	265072.Mfla_2254	6.352e-11	68.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2VKR6@28216|Betaproteobacteria,2KKID@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
MMD2_k127_4807203_25	1510531.JQJJ01000009_gene505	9.924e-19	91.0	COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,3JQRA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c	cyc	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
MMD2_k127_4807203_7	211586.SO_4266	1.761e-140	457.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria,2QB9N@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046983,GO:0070566,GO:0070733,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
MMD2_k127_4807203_15	869210.Marky_0140	2.131e-52	194.0	COG0566@1|root,COG0566@2|Bacteria,1WID3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylas_C,SpoU_methylase
MMD2_k127_4807203_6	1056820.KB900640_gene290	3.8e-141	466.0	COG3794@1|root,COG3794@2|Bacteria,1R29B@1224|Proteobacteria	1224|Proteobacteria	C	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
MMD2_k127_4825301_3	292459.STH554	8.556e-37	154.0	COG1735@1|root,COG1735@2|Bacteria,1TS8I@1239|Firmicutes,249N0@186801|Clostridia	186801|Clostridia	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
MMD2_k127_4825301_2	84531.JMTZ01000001_gene2231	6.526e-43	163.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1XB4G@135614|Xanthomonadales	135614|Xanthomonadales	K	Integron-associated effector binding protein	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
MMD2_k127_4825301_4	243365.CV_1302	2.226e-18	87.0	COG3449@1|root,COG4977@1|root,COG3449@2|Bacteria,COG4977@2|Bacteria,1QTW6@1224|Proteobacteria,2WH6J@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like
MMD2_k127_4825301_1	485913.Krac_9606	4.996e-59	216.0	COG2267@1|root,COG2267@2|Bacteria,2G8RT@200795|Chloroflexi	200795|Chloroflexi	I	Alpha/beta hydrolase family	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
MMD2_k127_4825301_0	861299.J421_1109	1.279e-221	694.0	COG1132@1|root,COG1132@2|Bacteria,1ZUSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
MMD2_k127_4828951_3	196367.JNFG01000199_gene3405	7.284e-108	351.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2VJXA@28216|Betaproteobacteria,1K051@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM amidohydrolase 2	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMD2_k127_4828951_0	861299.J421_0704	2.093e-217	703.0	COG0577@1|root,COG0577@2|Bacteria,1ZUI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_4828951_1	925409.KI911562_gene2549	1.367e-183	595.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
MMD2_k127_4828951_2	627192.SLG_05610	1.705e-168	573.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2K3KA@204457|Sphingomonadales	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_4828951_4	1254432.SCE1572_04735	1.265e-105	350.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,42SVA@68525|delta/epsilon subdivisions,2WPFH@28221|Deltaproteobacteria,2Z1X4@29|Myxococcales	28221|Deltaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMD2_k127_4828951_6	1121920.AUAU01000006_gene301	1.628e-39	159.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4828951_5	1245469.S58_53950	5.618e-64	236.0	COG3964@1|root,COG3964@2|Bacteria,1MVC7@1224|Proteobacteria,2TSUD@28211|Alphaproteobacteria,3JSBJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
MMD2_k127_4867002_4	331869.BAL199_05144	1.781e-65	230.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,4BPJE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	MA20_23640	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMD2_k127_4867002_1	1379270.AUXF01000005_gene457	6.615e-95	316.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_4867002_2	215803.DB30_3562	1.889e-79	286.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42U6K@68525|delta/epsilon subdivisions,2WQ4K@28221|Deltaproteobacteria,2YZCG@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
MMD2_k127_4867002_3	1411685.U062_00350	1.878e-66	248.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,1S6CX@1236|Gammaproteobacteria,1JA9P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMD2_k127_4867002_0	1122139.KB907865_gene1461	7.285e-102	341.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,1RMTW@1236|Gammaproteobacteria,1XPMH@135619|Oceanospirillales	135619|Oceanospirillales	C	NADPH quinone	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_487664_2	1121957.ATVL01000011_gene3572	2.919e-81	280.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia	976|Bacteroidetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
MMD2_k127_487664_4	627192.SLG_20090	6.15e-42	157.0	COG3631@1|root,COG3631@2|Bacteria,1N5XE@1224|Proteobacteria,2V5KX@28211|Alphaproteobacteria,2K76M@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
MMD2_k127_487664_3	1123020.AUIE01000005_gene4259	4.933e-69	243.0	COG2267@1|root,COG2267@2|Bacteria,1N9CI@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMD2_k127_487664_5	1125863.JAFN01000001_gene3374	4.242e-20	106.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42P1P@68525|delta/epsilon subdivisions,2WJ99@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TAT_signal,TPR_16,TPR_19
MMD2_k127_487664_0	1123393.KB891326_gene153	3.327e-156	506.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VP8B@28216|Betaproteobacteria,1KSE5@119069|Hydrogenophilales	119069|Hydrogenophilales	EH	chorismate binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Anth_synt_I_N,Chorismate_bind
MMD2_k127_487664_8	767029.HMPREF9154_0090	2.192e-06	58.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMD2_k127_487664_7	187303.BN69_3199	2.547e-08	60.0	COG4691@1|root,COG4691@2|Bacteria	2|Bacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	Arc
MMD2_k127_487664_6	215803.DB30_1357	4.099e-09	67.0	COG0666@1|root,COG0666@2|Bacteria,1PEGV@1224|Proteobacteria,43A19@68525|delta/epsilon subdivisions,2X8WZ@28221|Deltaproteobacteria,2Z0SS@29|Myxococcales	28221|Deltaproteobacteria	S	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_4
MMD2_k127_487664_1	713586.KB900536_gene740	6.598e-102	337.0	COG0294@1|root,COG0801@1|root,COG0294@2|Bacteria,COG0801@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1WXND@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
MMD2_k127_4887172_4	32042.PstZobell_12409	3.861e-35	136.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1Z0DW@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
MMD2_k127_4887172_3	227377.CBU_1594	1.5e-42	160.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1JEBS@118969|Legionellales	118969|Legionellales	S	Yqey-like protein	lporfX	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
MMD2_k127_4887172_6	1234364.AMSF01000085_gene2961	1.888e-23	100.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,1X7FD@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
MMD2_k127_4887172_0	765910.MARPU_06210	3.693e-127	415.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1WWRX@135613|Chromatiales	135613|Chromatiales	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
MMD2_k127_4887172_5	1177181.T9A_00502	4.241e-33	131.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
MMD2_k127_4887172_8	1469245.JFBG01000052_gene2157	3.421e-17	87.0	COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK2	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
MMD2_k127_4887172_1	1123399.AQVE01000022_gene358	2.156e-89	301.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,463MH@72273|Thiotrichales	72273|Thiotrichales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMD2_k127_4887172_7	265072.Mfla_0230	1.545e-22	106.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,2KKBV@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
MMD2_k127_4887172_2	439235.Dalk_3909	2.365e-47	178.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QX@1224|Proteobacteria,431N8@68525|delta/epsilon subdivisions,2WWXI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
MMD2_k127_4887172_9	439235.Dalk_3908	5.245e-13	71.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QU@1224|Proteobacteria,431N3@68525|delta/epsilon subdivisions,2WWWX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMD2_k127_4909810_4	1038866.KB902813_gene2034	1.125e-157	518.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_4909810_20	1040989.AWZU01000035_gene1786	2.486e-26	113.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,2UGVG@28211|Alphaproteobacteria,3K235@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
MMD2_k127_4909810_19	1040989.AWZU01000005_gene358	3.037e-42	160.0	COG0071@1|root,COG0071@2|Bacteria,1PSB0@1224|Proteobacteria,2UH0E@28211|Alphaproteobacteria,3K5V7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
MMD2_k127_4909810_18	1177928.TH2_16901	1.346e-42	171.0	290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,2UIQD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4909810_13	114615.BRADO3663	1.703e-66	233.0	COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,2TV0I@28211|Alphaproteobacteria,3JTZ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
MMD2_k127_4909810_2	472759.Nhal_0363	2.713e-174	576.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1X28I@135613|Chromatiales	135613|Chromatiales	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
MMD2_k127_4909810_15	1279019.ARQK01000051_gene1406	1.446e-64	239.0	COG1587@1|root,COG1587@2|Bacteria,1N93T@1224|Proteobacteria,1S367@1236|Gammaproteobacteria,1X0NB@135613|Chromatiales	135613|Chromatiales	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
MMD2_k127_4909810_16	570967.JMLV01000008_gene1314	1.012e-48	179.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2UDH7@28211|Alphaproteobacteria,2JTNM@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial protein of unknown function (DUF934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
MMD2_k127_4909810_1	1177928.TH2_11279	7.748e-233	734.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria,2JSH9@204441|Rhodospirillales	204441|Rhodospirillales	C	Sulfite reductase	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
MMD2_k127_4909810_22	1101190.ARWB01000001_gene3787	4.61e-12	73.0	2EG12@1|root,339T3@2|Bacteria,1NGID@1224|Proteobacteria,2UK0A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2849)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2849
MMD2_k127_4909810_10	344747.PM8797T_31038	1.379e-90	313.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,F5_F8_type_C
MMD2_k127_4909810_14	1120936.KB907215_gene4141	4.966e-66	232.0	COG3558@1|root,COG3558@2|Bacteria,2IFFG@201174|Actinobacteria,4EJ6A@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1348)	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
MMD2_k127_4909810_6	483219.LILAB_29135	7.558e-116	387.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWSR@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_4909810_12	247634.GPB2148_522	9.377e-74	262.0	COG1073@1|root,COG1073@2|Bacteria,1NEVB@1224|Proteobacteria	1224|Proteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4909810_9	43989.cce_4306	1.237e-90	314.0	COG0277@1|root,COG0277@2|Bacteria,1GARH@1117|Cyanobacteria	1117|Cyanobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
MMD2_k127_4909810_0	314278.NB231_07942	8.904e-279	865.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales	135613|Chromatiales	P	Belongs to the sulfate adenylyltransferase family	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
MMD2_k127_4909810_8	322710.Avin_29450	1.129e-91	314.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645,ko:K13935	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
MMD2_k127_4909810_3	518766.Rmar_1842	2.64e-163	533.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1FJQB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	MFS/sugar transport protein	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
MMD2_k127_4909810_21	136993.KB900627_gene392	1.338e-16	89.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4909810_23	604331.AUHY01000095_gene623	3.19e-07	62.0	2CBFC@1|root,32RYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4909810_7	1210884.HG799463_gene10248	4.169e-110	374.0	COG0842@1|root,COG0842@2|Bacteria,2IZDF@203682|Planctomycetes	203682|Planctomycetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMD2_k127_4909810_5	1123508.JH636445_gene6659	4.443e-133	427.0	COG1131@1|root,COG1131@2|Bacteria,2IYFJ@203682|Planctomycetes	203682|Planctomycetes	V	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_4909810_17	309801.trd_1777	4.437e-45	181.0	COG0111@1|root,COG0111@2|Bacteria,2G67B@200795|Chloroflexi,27XG7@189775|Thermomicrobia	189775|Thermomicrobia	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
MMD2_k127_4909810_11	107636.JQNK01000009_gene1854	2.073e-78	274.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_4932622_21	1121015.N789_02730	6.706e-93	313.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1X313@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
MMD2_k127_4932622_12	1216966.BAUC01000017_gene664	8.646e-133	430.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSSON_1240.SSON_1444,iYL1228.KPN_02176	Phe_tRNA-synt_N,tRNA-synt_2d
MMD2_k127_4932622_35	765910.MARPU_05535	2.583e-48	175.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1WYQC@135613|Chromatiales	135613|Chromatiales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
MMD2_k127_4932622_43	686340.Metal_0697	3.183e-19	90.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,1XFG5@135618|Methylococcales	135618|Methylococcales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
MMD2_k127_4932622_30	472759.Nhal_3207	4.142e-69	239.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1WWSS@135613|Chromatiales	135613|Chromatiales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
MMD2_k127_4932622_40	234267.Acid_4087	3.864e-30	137.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Ank_4,Peptidase_M10
MMD2_k127_4932622_38	926550.CLDAP_09390	6.238e-40	160.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
MMD2_k127_4932622_3	519989.ECTPHS_13420	1.666e-317	985.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1WW4U@135613|Chromatiales	135613|Chromatiales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
MMD2_k127_4932622_7	686340.Metal_2799	6.266e-144	466.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XE5B@135618|Methylococcales	135618|Methylococcales	E	PFAM Aminotransferase, class I	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_4932622_20	497964.CfE428DRAFT_0387	4.316e-93	323.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMD2_k127_4932622_19	1267534.KB906758_gene2256	3.34e-94	314.0	COG0745@1|root,COG0745@2|Bacteria,3Y522@57723|Acidobacteria,2JKQX@204432|Acidobacteriia	204432|Acidobacteriia	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_4932622_26	234267.Acid_7567	3.28e-80	284.0	COG1538@1|root,COG1538@2|Bacteria,3Y3JU@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
MMD2_k127_4932622_1	204669.Acid345_1699	0.0	1284.0	COG0841@1|root,COG0841@2|Bacteria,3Y2RX@57723|Acidobacteria,2JIU0@204432|Acidobacteriia	204432|Acidobacteriia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMD2_k127_4932622_0	497964.CfE428DRAFT_0384	0.0	1497.0	COG0841@1|root,COG0841@2|Bacteria,46S7J@74201|Verrucomicrobia	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMD2_k127_4932622_32	497964.CfE428DRAFT_0385	1.63e-67	240.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
MMD2_k127_4932622_24	497964.CfE428DRAFT_0386	9.094e-87	302.0	COG0845@1|root,COG0845@2|Bacteria,46SYN@74201|Verrucomicrobia	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMD2_k127_4932622_25	272134.KB731324_gene6680	9.782e-87	298.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
MMD2_k127_4932622_27	1089545.KB913037_gene6024	1.532e-76	263.0	COG0346@1|root,COG0346@2|Bacteria,2IPGW@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
MMD2_k127_4932622_14	1123256.KB907925_gene1328	4.143e-117	402.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1X4K6@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia	gatAX	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase,Lipocalin_5
MMD2_k127_4932622_37	1007104.SUS17_2415	8.088e-41	166.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,2KCBM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4932622_42	555793.WSK_4046	6.648e-22	103.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4932622_22	1366050.N234_22405	2.968e-91	309.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2W9HD@28216|Betaproteobacteria,1KD5E@119060|Burkholderiaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD2_k127_4932622_18	438753.AZC_3351	1.682e-98	326.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2TTGT@28211|Alphaproteobacteria,3F064@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	Aldolase/RraA	ligK	-	4.1.3.17	ko:K02553,ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000,ko03019	-	-	-	RraA-like
MMD2_k127_4932622_17	867903.ThesuDRAFT_01275	4.219e-109	365.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,3WD6V@538999|Clostridiales incertae sedis	186801|Clostridia	C	acyl-CoA transferase carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
MMD2_k127_4932622_15	243365.CV_3901	2.498e-115	379.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,2KQ12@206351|Neisseriales	206351|Neisseriales	M	Psort location Cytoplasmic, score 8.96	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMD2_k127_4932622_45	743720.Psefu_1920	6.114e-12	69.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,1YVNY@136845|Pseudomonas putida group	1236|Gammaproteobacteria	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comEA	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
MMD2_k127_4932622_29	1056512.D515_01939	6.281e-71	254.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1XU1S@135623|Vibrionales	135623|Vibrionales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19,TPR_7,TPR_8
MMD2_k127_4932622_36	1158762.KB898040_gene1474	6.782e-42	155.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1WYM5@135613|Chromatiales	135613|Chromatiales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMD2_k127_4932622_4	396588.Tgr7_1543	7.455e-272	848.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1WVVK@135613|Chromatiales	135613|Chromatiales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
MMD2_k127_4932622_31	349124.Hhal_0564	8.52e-69	252.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1WXNU@135613|Chromatiales	135613|Chromatiales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
MMD2_k127_4932622_10	396588.Tgr7_1541	6.239e-141	460.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1WX54@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
MMD2_k127_4932622_11	1123253.AUBD01000001_gene1641	6.961e-136	445.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1X4R7@135614|Xanthomonadales	135614|Xanthomonadales	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
MMD2_k127_4932622_6	572477.Alvin_2085	3.329e-157	504.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1WWZH@135613|Chromatiales	135613|Chromatiales	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMD2_k127_4932622_9	396588.Tgr7_1536	1.185e-142	494.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1WWHV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
MMD2_k127_4932622_2	1049564.TevJSym_ad01400	0.0	1199.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1J52I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMD2_k127_4932622_5	396588.Tgr7_1531	1.009e-159	514.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMD2_k127_4932622_23	1397528.Q671_03020	1.661e-87	298.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1XH4S@135619|Oceanospirillales	135619|Oceanospirillales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
MMD2_k127_4932622_34	1122212.AULO01000011_gene429	5.052e-53	204.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1XJMU@135619|Oceanospirillales	135619|Oceanospirillales	S	haloacid dehalogenase-like hydrolase	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMD2_k127_4932622_16	1286106.MPL1_09410	6.845e-113	384.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,46007@72273|Thiotrichales	72273|Thiotrichales	S	DNA recombination protein RmuC	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
MMD2_k127_4932622_33	1177181.T9A_01486	1.416e-66	251.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,1XH47@135619|Oceanospirillales	135619|Oceanospirillales	IQ	reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD2_k127_4932622_41	700598.Niako_2492	2.294e-25	114.0	2EA99@1|root,334DQ@2|Bacteria,4P45M@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4932622_39	1201288.M900_1021	6.887e-32	132.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2MU6W@213481|Bdellovibrionales,2WQKU@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMD2_k127_4932622_44	627192.SLG_26310	1.036e-16	89.0	COG3631@1|root,COG3631@2|Bacteria,1NI1R@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_4932622_28	1267533.KB906734_gene3858	1.359e-74	266.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,MetW,Methyltransf_2
MMD2_k127_4932622_13	452637.Oter_1902	2.84e-126	424.0	COG5000@1|root,COG5000@2|Bacteria,46V9C@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
MMD2_k127_4932622_8	1163407.UU7_14033	8.095e-143	465.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X5K1@135614|Xanthomonadales	135614|Xanthomonadales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD2_k127_4950231_3	765910.MARPU_09370	6.321e-83	286.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria,1WWJG@135613|Chromatiales	135613|Chromatiales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
MMD2_k127_4950231_0	396588.Tgr7_0331	6.87e-159	511.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
MMD2_k127_4950231_2	883126.HMPREF9710_01128	6.235e-87	300.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,476PV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
MMD2_k127_4950231_1	1123229.AUBC01000030_gene1399	8.238e-100	340.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TS6B@28211|Alphaproteobacteria,3JUYU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Trypsin	-	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
MMD2_k127_4990772_4	666685.R2APBS1_2750	5.867e-31	123.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1S28D@1236|Gammaproteobacteria,1X9WT@135614|Xanthomonadales	135614|Xanthomonadales	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
MMD2_k127_4990772_1	1297569.MESS2_1170003	2.114e-80	268.0	COG3791@1|root,COG3791@2|Bacteria,1RH2A@1224|Proteobacteria,2U731@28211|Alphaproteobacteria,43K3W@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMD2_k127_4990772_3	118161.KB235922_gene333	6.56e-64	225.0	COG3917@1|root,COG3917@2|Bacteria,1GE7Z@1117|Cyanobacteria	1117|Cyanobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
MMD2_k127_4990772_6	1463926.JOCA01000006_gene3963	6.938e-07	56.0	COG0662@1|root,COG0662@2|Bacteria,2INXJ@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD2_k127_4990772_2	1380394.JADL01000005_gene5416	2.286e-76	262.0	COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,2TT0U@28211|Alphaproteobacteria,2JRW6@204441|Rhodospirillales	204441|Rhodospirillales	S	DJ-1/PfpI family	-	-	4.2.1.103	ko:K18199	ko00930,map00930	-	R05771	RC01467	ko00000,ko00001,ko01000,ko01002	-	-	-	DJ-1_PfpI
MMD2_k127_4990772_0	926560.KE387023_gene3658	8.288e-95	317.0	COG0500@1|root,COG2226@2|Bacteria,1WMEJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_4998456_18	1328313.DS2_02033	4.043e-42	165.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria,46D27@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	csgA	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD2_k127_4998456_22	629773.AORY01000005_gene2660	3.245e-24	115.0	COG2207@1|root,COG2207@2|Bacteria,1MXT9@1224|Proteobacteria,2U0UP@28211|Alphaproteobacteria,2K7AB@204457|Sphingomonadales	204457|Sphingomonadales	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
MMD2_k127_4998456_16	243233.MCA2459	2.97e-46	177.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,1S0GN@1236|Gammaproteobacteria,1XDV0@135618|Methylococcales	135618|Methylococcales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD2_k127_4998456_14	1123401.JHYQ01000001_gene1701	1.366e-53	192.0	COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,1S77V@1236|Gammaproteobacteria,460U2@72273|Thiotrichales	72273|Thiotrichales	S	CYTH	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
MMD2_k127_4998456_11	522306.CAP2UW1_2475	3.282e-62	222.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,1KQWF@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMD2_k127_4998456_4	396588.Tgr7_1754	5.287e-104	348.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1WXR0@135613|Chromatiales	135613|Chromatiales	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
MMD2_k127_4998456_19	1123256.KB907935_gene2475	1.046e-37	150.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1X3NG@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
MMD2_k127_4998456_9	1123257.AUFV01000002_gene2434	1.248e-63	228.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1X3NA@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine	deoD	-	2.4.2.44	ko:K19696	ko00270,ko01100,map00270,map01100	-	R09668	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
MMD2_k127_4998456_24	1173028.ANKO01000014_gene1006	6.63e-17	92.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H8H6@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
MMD2_k127_4998456_26	1538295.JY96_14190	1.39e-12	79.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,1KMB6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	diguanylate cyclase	pleD	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
MMD2_k127_4998456_25	1198232.CYCME_1744	2.082e-15	85.0	2EC19@1|root,3360G@2|Bacteria,1PBYU@1224|Proteobacteria,1SD34@1236|Gammaproteobacteria,461FP@72273|Thiotrichales	72273|Thiotrichales	S	Peptidoglycan-binding protein, CsiV	-	-	-	-	-	-	-	-	-	-	-	-	CsiV
MMD2_k127_4998456_0	349124.Hhal_1257	0.0	1177.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales	135613|Chromatiales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
MMD2_k127_4998456_1	380358.XALC_0321	5.085e-180	570.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1X34Q@135614|Xanthomonadales	135614|Xanthomonadales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
MMD2_k127_4998456_2	1385515.N791_00730	8.195e-149	481.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1X3G9@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
MMD2_k127_4998456_7	426355.Mrad2831_0802	4.953e-72	250.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TU0N@28211|Alphaproteobacteria,1JSI3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	MA20_23565	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
MMD2_k127_4998456_23	379066.GAU_1445	1.988e-22	101.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_23570	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_34
MMD2_k127_4998456_20	1340493.JNIF01000003_gene1914	3.141e-32	133.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_4998456_28	640513.Entas_1834	6.289e-05	46.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1RRI3@1236|Gammaproteobacteria,3X10G@547|Enterobacter	1236|Gammaproteobacteria	O	Belongs to the GST superfamily	gst	GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0044424,GO:0044464,GO:0046677,GO:0050896,GO:1901700	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_2,GST_N_3
MMD2_k127_4998456_21	1395571.TMS3_0100830	3.952e-29	122.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,1RRI3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the GST superfamily	gst	GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0044424,GO:0044464,GO:0046677,GO:0050896,GO:1901700	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_2,GST_N_3
MMD2_k127_4998456_8	1515746.HR45_06840	9.36e-64	224.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,1S2DE@1236|Gammaproteobacteria,2QB2K@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Uncharacterized protein family, UPF0114	Z012_09380	-	-	-	-	-	-	-	-	-	-	-	UPF0114
MMD2_k127_4998456_17	1223521.BBJX01000004_gene2538	2.539e-45	179.0	COG2199@1|root,COG3706@2|Bacteria,1RDWG@1224|Proteobacteria,2WF41@28216|Betaproteobacteria,4AI37@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMD2_k127_4998456_6	1333998.M2A_2723	4.939e-80	282.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2TU60@28211|Alphaproteobacteria,4BR27@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
MMD2_k127_4998456_15	1038860.AXAP01000097_gene5020	1.064e-48	181.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
MMD2_k127_4998456_3	311402.Avi_5950	1.385e-111	380.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2VCNC@28211|Alphaproteobacteria,4BJVX@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Retinal pigment epithelial membrane protein	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
MMD2_k127_4998456_5	246197.MXAN_5937	1.55e-85	289.0	COG3145@1|root,COG3145@2|Bacteria,1N5HB@1224|Proteobacteria,4352P@68525|delta/epsilon subdivisions,2WZDR@28221|Deltaproteobacteria,2Z1WW@29|Myxococcales	28221|Deltaproteobacteria	L	2OG-Fe(II) oxygenase superfamily	-	-	1.14.11.33	ko:K03919	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	2OG-FeII_Oxy_2
MMD2_k127_4998456_10	187272.Mlg_1616	1.073e-62	224.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S5BM@1236|Gammaproteobacteria,1X29N@135613|Chromatiales	135613|Chromatiales	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
MMD2_k127_4998456_27	1515746.HR45_04290	2.738e-11	67.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1TB3Y@1236|Gammaproteobacteria,2QD5D@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1289
MMD2_k127_5074928_12	1128421.JAGA01000002_gene366	8.375e-55	196.0	COG0796@1|root,COG0796@2|Bacteria,2NP3D@2323|unclassified Bacteria	2|Bacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
MMD2_k127_5074928_28	1101195.Meth11DRAFT_1463	9.162e-28	126.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5074928_31	1340493.JNIF01000003_gene2122	8.345e-22	110.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5074928_14	661478.OP10G_1921	2.383e-53	201.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
MMD2_k127_5074928_9	215803.DB30_6887	8.089e-64	228.0	COG0789@1|root,COG0789@2|Bacteria,1REB7@1224|Proteobacteria,4347C@68525|delta/epsilon subdivisions,2X9UQ@28221|Deltaproteobacteria,2YWCK@29|Myxococcales	28221|Deltaproteobacteria	K	TipAS antibiotic-recognition domain	-	-	-	ko:K21744	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TipAS
MMD2_k127_5074928_3	1116472.MGMO_7c00210	1.507e-182	585.0	COG3211@1|root,COG3211@2|Bacteria,1R7E2@1224|Proteobacteria,1SCSQ@1236|Gammaproteobacteria,1XGF9@135618|Methylococcales	135618|Methylococcales	S	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
MMD2_k127_5074928_27	1265313.HRUBRA_00788	5.652e-28	124.0	2F5HB@1|root,33Y2W@2|Bacteria,1NVRQ@1224|Proteobacteria,1SNZS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5074928_26	582744.Msip34_1485	1.077e-38	162.0	COG1538@1|root,COG1538@2|Bacteria,1RFMJ@1224|Proteobacteria,2W2GG@28216|Betaproteobacteria,2KMD4@206350|Nitrosomonadales	206350|Nitrosomonadales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD2_k127_5074928_30	1267005.KB911262_gene3370	9.575e-25	120.0	COG0845@1|root,COG0845@2|Bacteria,1Q0J0@1224|Proteobacteria,2UEW1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5074928_0	670307.HYPDE_28798	2.451e-315	995.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMD2_k127_5074928_1	1123392.AQWL01000005_gene3146	1.482e-240	770.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,2VK9C@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	-	DUF2156,LPG_synthase_TM
MMD2_k127_5074928_25	861299.J421_0109	8.097e-39	153.0	COG3946@1|root,COG3946@2|Bacteria	2|Bacteria	U	Bacterial virulence protein (VirJ)	acvB	-	-	-	-	-	-	-	-	-	-	-	VirJ
MMD2_k127_5074928_29	1209072.ALBT01000032_gene2078	1.101e-27	120.0	2DYRQ@1|root,34ATV@2|Bacteria,1PQUZ@1224|Proteobacteria,1ST19@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cytochrome C'	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
MMD2_k127_5074928_5	1121272.KB903283_gene5019	9.539e-113	390.0	COG1215@1|root,COG1215@2|Bacteria,2GKFI@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
MMD2_k127_5074928_21	234267.Acid_4171	1.683e-41	166.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_5074928_24	883126.HMPREF9710_03144	4.432e-39	151.0	COG0454@1|root,COG0456@2|Bacteria,1RKFU@1224|Proteobacteria,2VUBE@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMD2_k127_5074928_20	1117318.PRUB_18097	2.284e-43	162.0	COG0454@1|root,COG0456@2|Bacteria,1QTYD@1224|Proteobacteria,1T1S0@1236|Gammaproteobacteria,2Q2SU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
MMD2_k127_5074928_18	1280950.HJO_14382	1.026e-47	181.0	COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U69N@28211|Alphaproteobacteria,43XNX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,PCMT
MMD2_k127_5074928_32	1123073.KB899241_gene2134	3.864e-13	80.0	2DP0A@1|root,3300Q@2|Bacteria,1N78Y@1224|Proteobacteria,1SH09@1236|Gammaproteobacteria,1X7R4@135614|Xanthomonadales	135614|Xanthomonadales	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
MMD2_k127_5074928_23	765912.Thimo_1347	1.022e-39	167.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,1WWDC@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
MMD2_k127_5074928_8	1122194.AUHU01000020_gene3494	3.565e-70	249.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
MMD2_k127_5074928_22	1123377.AUIV01000015_gene276	5.927e-41	159.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1X68Z@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
MMD2_k127_5074928_2	472759.Nhal_2617	1.726e-186	608.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1WWJW@135613|Chromatiales	135613|Chromatiales	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
MMD2_k127_5074928_16	1510531.JQJJ01000010_gene2228	1.804e-50	192.0	COG0614@1|root,COG0614@2|Bacteria,1RAUP@1224|Proteobacteria,2TUB0@28211|Alphaproteobacteria,3JT3Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
MMD2_k127_5074928_6	1333998.M2A_2999	1.564e-104	358.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,4BQ55@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
MMD2_k127_5074928_11	316056.RPC_4255	9.002e-61	219.0	COG1120@1|root,COG1120@2|Bacteria,1QPWJ@1224|Proteobacteria,2U1TK@28211|Alphaproteobacteria,3JUXQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
MMD2_k127_5074928_13	1245469.S58_00300	2.103e-54	199.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,2U5IH@28211|Alphaproteobacteria,3K65Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_2,GST_N_3
MMD2_k127_5074928_19	1304275.C41B8_14445	1.088e-46	176.0	COG0558@1|root,COG0558@2|Bacteria,1P1W5@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMD2_k127_5074928_17	1033802.SSPSH_002496	1.565e-48	190.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4,Sterile
MMD2_k127_5074928_10	246197.MXAN_6765	1.375e-62	222.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,42RPV@68525|delta/epsilon subdivisions,2WNQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_5074928_4	1297742.A176_01884	2.952e-162	541.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,42MX2@68525|delta/epsilon subdivisions,2WIUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_5074928_7	243231.GSU2186	4.061e-93	343.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,42Q9D@68525|delta/epsilon subdivisions,2WK21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
MMD2_k127_5074928_15	1150469.RSPPHO_03261	1.78e-51	183.0	2DP8N@1|root,3311E@2|Bacteria,1NC4X@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5078222_2	382464.ABSI01000010_gene3727	9.379e-42	169.0	COG3243@1|root,COG3243@2|Bacteria	2|Bacteria	I	poly(R)-hydroxyalkanoic acid synthase	phaC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	iJN678.phbC	Abhydrolase_1
MMD2_k127_5078222_1	526225.Gobs_2383	9.039e-54	201.0	COG2267@1|root,COG2267@2|Bacteria,2I0NW@201174|Actinobacteria,4EVDX@85013|Frankiales	201174|Actinobacteria	I	TAP-like protein	-	-	3.1.1.76	ko:K22250	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
MMD2_k127_5078222_0	519989.ECTPHS_08598	2.749e-115	390.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1WWVE@135613|Chromatiales	135613|Chromatiales	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
MMD2_k127_508487_6	1297742.A176_06407	1.226e-69	244.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
MMD2_k127_508487_4	58344.JOEL01000022_gene988	3.356e-83	289.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
MMD2_k127_508487_0	702113.PP1Y_AT12349	4.061e-170	550.0	COG1858@1|root,COG1858@2|Bacteria,1REQ9@1224|Proteobacteria,2U8Q0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_508487_21	935863.AWZR01000004_gene417	1.073e-06	62.0	2BU8Z@1|root,32PIG@2|Bacteria,1NUGX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMD2_k127_508487_2	627192.SLG_34640	1.286e-134	440.0	COG2755@1|root,COG2755@2|Bacteria,1MXBN@1224|Proteobacteria,2U079@28211|Alphaproteobacteria,2K27U@204457|Sphingomonadales	204457|Sphingomonadales	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMD2_k127_508487_10	1166948.JPZL01000001_gene3157	2.985e-42	158.0	COG2140@1|root,COG2140@2|Bacteria,1QZHH@1224|Proteobacteria,1SF0W@1236|Gammaproteobacteria,1XQQB@135619|Oceanospirillales	135619|Oceanospirillales	G	Oxalate decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_508487_12	1192868.CAIU01000035_gene4307	3.079e-35	138.0	COG1695@1|root,COG1695@2|Bacteria,1PMEP@1224|Proteobacteria,2V018@28211|Alphaproteobacteria,43QT4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMD2_k127_508487_20	1088721.NSU_2826	1.045e-06	61.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_508487_8	1131813.AQVT01000001_gene2839	5.199e-61	219.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2UCUE@28211|Alphaproteobacteria,1JTUK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Staphylococcal nuclease homologues	exoI2	-	-	ko:K16561	-	-	-	-	ko00000	-	-	-	SNase
MMD2_k127_508487_9	317025.Tcr_0235	5.003e-44	179.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1S5X2@1236|Gammaproteobacteria,462MH@72273|Thiotrichales	72273|Thiotrichales	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_508487_3	234267.Acid_2447	6.575e-95	325.0	COG3391@1|root,COG3391@2|Bacteria,3Y8A0@57723|Acidobacteria	57723|Acidobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD2_k127_508487_13	1298880.AUEV01000024_gene5278	8.337e-29	130.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
MMD2_k127_508487_14	105425.BBPL01000074_gene3840	1.829e-27	125.0	COG2020@1|root,COG2020@2|Bacteria,2HUDA@201174|Actinobacteria,2NIQ9@228398|Streptacidiphilus	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMD2_k127_508487_16	136993.KB900627_gene391	1.395e-23	105.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_508487_18	627192.SLG_09880	4.244e-16	90.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_508487_7	1163408.UU9_16426	6.438e-64	226.0	COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMD2_k127_508487_1	1267535.KB906767_gene3834	5.651e-147	497.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_508487_5	78579.XP_003661026.1	9.524e-70	252.0	2EBD3@1|root,2SHGJ@2759|Eukaryota,39TQZ@33154|Opisthokonta,3NZP0@4751|Fungi,3QR77@4890|Ascomycota,218S5@147550|Sordariomycetes,3UABU@5139|Sordariales,3HAHA@35718|Chaetomiaceae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_508487_15	1173027.Mic7113_2551	6.206e-27	115.0	COG1396@1|root,COG1396@2|Bacteria,1G7Q5@1117|Cyanobacteria,1HCFQ@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMD2_k127_508487_11	118173.KB235914_gene2725	4.061e-39	149.0	COG4679@1|root,COG4679@2|Bacteria,1G6N5@1117|Cyanobacteria,1HC3R@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
MMD2_k127_508487_22	96561.Dole_2340	0.0006317	43.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2WPHJ@28221|Deltaproteobacteria,2MKC1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
MMD2_k127_508487_17	717785.HYPMC_2741	1.06e-18	92.0	COG3386@1|root,COG3386@2|Bacteria,1MXB7@1224|Proteobacteria,2U2RZ@28211|Alphaproteobacteria,3N98Y@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMD2_k127_5141744_7	378806.STAUR_6729	1.153e-65	235.0	COG2085@1|root,COG2085@2|Bacteria,1RCXR@1224|Proteobacteria,43070@68525|delta/epsilon subdivisions,2WVFX@28221|Deltaproteobacteria,2Z1E9@29|Myxococcales	28221|Deltaproteobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
MMD2_k127_5141744_3	1379270.AUXF01000007_gene1065	6.083e-109	372.0	COG1055@1|root,COG1055@2|Bacteria,1ZU8M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	MatC_N
MMD2_k127_5141744_0	1288494.EBAPG3_22070	1.943e-229	722.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,2VHSM@28216|Betaproteobacteria,372JS@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	rosB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
MMD2_k127_5141744_6	596151.DesfrDRAFT_2051	1.742e-71	247.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MATW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
MMD2_k127_5141744_2	1123269.NX02_29030	5.07e-180	583.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2K2U3@204457|Sphingomonadales	204457|Sphingomonadales	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMD2_k127_5141744_4	1123242.JH636434_gene3417	9.684e-94	321.0	COG3823@1|root,COG3823@2|Bacteria,2IYW4@203682|Planctomycetes	203682|Planctomycetes	O	PFAM Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
MMD2_k127_5141744_9	290398.Csal_2901	4.07e-50	184.0	COG1670@1|root,COG1670@2|Bacteria,1RGKF@1224|Proteobacteria,1S28M@1236|Gammaproteobacteria,1XPBI@135619|Oceanospirillales	135619|Oceanospirillales	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
MMD2_k127_5141744_10	160492.XF_1834	1.566e-16	87.0	COG0526@1|root,COG0526@2|Bacteria,1RHMS@1224|Proteobacteria,1T0EJ@1236|Gammaproteobacteria,1XAAH@135614|Xanthomonadales	135614|Xanthomonadales	M	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
MMD2_k127_5141744_5	375286.mma_2596	2.466e-88	295.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VUIT@28216|Betaproteobacteria,476WJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
MMD2_k127_5141744_11	1121015.N789_10495	3.049e-13	78.0	2BU53@1|root,32PDZ@2|Bacteria,1Q8RD@1224|Proteobacteria,1TEUX@1236|Gammaproteobacteria,1XBUA@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019
MMD2_k127_5141744_8	757424.Hsero_3116	5.812e-56	200.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2VQM1@28216|Betaproteobacteria,474F3@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
MMD2_k127_5141744_1	595494.Tola_3041	2.888e-187	590.0	COG0006@1|root,COG0006@2|Bacteria,1MX9N@1224|Proteobacteria,1RMUP@1236|Gammaproteobacteria,1Y6AD@135624|Aeromonadales	135624|Aeromonadales	E	Creatinase/Prolidase N-terminal domain	-	-	3.5.3.3	ko:K08688	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566	RC00548,RC00549	ko00000,ko00001,ko01000	-	-	-	Creatinase_N,Peptidase_M24
MMD2_k127_51910_2	240015.ACP_3514	2.899e-218	704.0	COG0577@1|root,COG0577@2|Bacteria,3Y6R1@57723|Acidobacteria,2JMKX@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_51910_27	1123060.JONP01000006_gene4770	1.655e-10	72.0	2EPIU@1|root,33H5G@2|Bacteria,1PYWW@1224|Proteobacteria,2UU2V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_51910_10	935261.JAGL01000004_gene864	5.926e-104	353.0	COG0179@1|root,COG0179@2|Bacteria,1NTUI@1224|Proteobacteria,2U2F5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
MMD2_k127_51910_19	686340.Metal_3077	2.917e-32	144.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria,1XF4H@135618|Methylococcales	135618|Methylococcales	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
MMD2_k127_51910_16	1196835.A458_01070	4.627e-42	165.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,1Z0XQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
MMD2_k127_51910_9	1248916.ANFY01000004_gene1770	1.758e-109	372.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales	204457|Sphingomonadales	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
MMD2_k127_51910_18	555793.WSK_3235	1.843e-36	151.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_51910_13	41431.PCC8801_3875	4.346e-62	232.0	28J0M@1|root,2Z8XS@2|Bacteria,1G4XS@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_51910_22	1206733.BAGC01000041_gene2058	6.937e-27	119.0	COG2020@1|root,COG2020@2|Bacteria,2IP2M@201174|Actinobacteria,4G4WC@85025|Nocardiaceae	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMD2_k127_51910_11	264198.Reut_B5506	3.189e-90	308.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2VTG7@28216|Betaproteobacteria,1KGWJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	4.1.1.52	ko:K22213	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_2
MMD2_k127_51910_6	97096.XP_007790920.1	8.057e-129	430.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMD2_k127_51910_3	247634.GPB2148_3875	5.698e-163	538.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
MMD2_k127_51910_0	1366050.N234_20460	2.649e-237	746.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2VI0N@28216|Betaproteobacteria,1K0AQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMD2_k127_51910_17	314278.NB231_13781	1.236e-39	163.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,1WYD7@135613|Chromatiales	135613|Chromatiales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
MMD2_k127_51910_15	1134474.O59_002379	4.548e-47	179.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S7A2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_51910_14	1134474.O59_002380	8.605e-61	228.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1S5X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_51910_26	1340493.JNIF01000003_gene2122	5.917e-11	69.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_51910_25	1236959.BAMT01000015_gene2850	5.888e-24	112.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_51910_21	1123368.AUIS01000004_gene146	1.257e-27	115.0	COG0818@1|root,COG0818@2|Bacteria,1QCW0@1224|Proteobacteria,1T8PN@1236|Gammaproteobacteria,2ND85@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Prokaryotic diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
MMD2_k127_51910_24	1125863.JAFN01000001_gene3142	1.556e-24	114.0	COG0671@1|root,COG0671@2|Bacteria,1QUKE@1224|Proteobacteria,42XAW@68525|delta/epsilon subdivisions,2WSJV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
MMD2_k127_51910_23	349124.Hhal_0376	6.076e-26	117.0	COG2867@1|root,COG2867@2|Bacteria,1QZ93@1224|Proteobacteria,1T41V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_51910_12	1386089.N865_15080	9.52e-67	240.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4FFYW@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD2_k127_51910_5	614083.AWQR01000022_gene106	5.112e-141	455.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2VP80@28216|Betaproteobacteria,4ADEX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	4.1.1.103,4.1.1.46	ko:K07045,ko:K14333,ko:K20941	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R00821,R11353	RC00390,RC00569	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
MMD2_k127_51910_8	1040989.AWZU01000009_gene1068	1.223e-120	404.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2TRBF@28211|Alphaproteobacteria,3JXPV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4
MMD2_k127_51910_1	460265.Mnod_0288	5.24e-221	700.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,1JTP3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	acsf	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMD2_k127_51910_7	395964.KE386496_gene2438	1.906e-121	424.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,3NACS@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Dehydrogenase E1 component	acoA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
MMD2_k127_51910_4	991905.SL003B_1083	3.82e-152	486.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,4BRTY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMD2_k127_51910_20	443598.AUFA01000003_gene2011	4.235e-29	132.0	COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,2TTKB@28211|Alphaproteobacteria,3JWKU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMD2_k127_51910_29	498761.HM1_0137	3.982e-06	53.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
MMD2_k127_5198060_5	1254432.SCE1572_16030	2.497e-97	328.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMD2_k127_5198060_6	1192759.AKIB01000026_gene2158	7.605e-77	269.0	COG1396@1|root,COG1396@2|Bacteria,1MUG2@1224|Proteobacteria,2TR3R@28211|Alphaproteobacteria,2K94Y@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
MMD2_k127_5198060_0	393595.ABO_1267	7.721e-296	925.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1XHJX@135619|Oceanospirillales	135619|Oceanospirillales	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
MMD2_k127_5198060_1	1282361.ABAC402_08860	9.64e-235	750.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2TWA4@28211|Alphaproteobacteria,2KI21@204458|Caulobacterales	204458|Caulobacterales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_5198060_3	1128421.JAGA01000001_gene2449	3.411e-122	413.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2,TOBE_3
MMD2_k127_5198060_2	395495.Lcho_3804	1.996e-139	453.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,1KJR9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
MMD2_k127_5198060_4	498211.CJA_2242	3.568e-101	336.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,1RS0W@1236|Gammaproteobacteria,1FH2Q@10|Cellvibrio	1236|Gammaproteobacteria	O	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iJN746.PP_5170	BPD_transp_1
MMD2_k127_5198060_7	153948.NAL212_2090	1.578e-60	226.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,3729U@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
MMD2_k127_5230936_0	748658.KB907312_gene1638	5.086e-192	616.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,1RRFQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Arsenical pump-driving ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
MMD2_k127_5230936_5	395019.Bmul_5667	1.147e-45	169.0	2BU42@1|root,32PCX@2|Bacteria,1PITZ@1224|Proteobacteria,2W7D7@28216|Betaproteobacteria,1KECK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF2703)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2703
MMD2_k127_5230936_8	1158150.KB906247_gene2320	3.438e-29	128.0	COG1276@1|root,COG1276@2|Bacteria,1RDS9@1224|Proteobacteria,1S6U4@1236|Gammaproteobacteria,1X22N@135613|Chromatiales	135613|Chromatiales	P	Copper resistance protein D	-	-	-	ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	CopD
MMD2_k127_5230936_13	1381751.JAJB01000115_gene2929	1.21e-08	61.0	COG2372@1|root,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria,4F937@85019|Brevibacteriaceae	201174|Actinobacteria	S	CopC domain	-	-	-	ko:K07156,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
MMD2_k127_5230936_1	234267.Acid_1779	3.031e-106	372.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.1.3.15,1.1.3.46	ko:K00104,ko:K16422	ko00261,ko00630,ko01055,ko01100,ko01110,ko01120,ko01130,map00261,map00630,map01055,map01100,map01110,map01120,map01130	-	R00475,R06633	RC00042,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
MMD2_k127_5230936_6	404589.Anae109_2778	1.58e-34	138.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,4399V@68525|delta/epsilon subdivisions,2X4HB@28221|Deltaproteobacteria,2YZ0N@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMD2_k127_5230936_4	765912.Thimo_0453	5.006e-54	196.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1WY9X@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
MMD2_k127_5230936_10	1280947.HY30_12510	1.501e-11	73.0	COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,2UGMI@28211|Alphaproteobacteria,43Y8Q@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
MMD2_k127_5230936_7	1122137.AQXF01000002_gene377	3.395e-33	143.0	COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,2UIQ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5230936_16	450851.PHZ_c2786	5.941e-05	48.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,2TVDN@28211|Alphaproteobacteria,2KJ1A@204458|Caulobacterales	204458|Caulobacterales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_5230936_9	1144305.PMI02_01782	4.263e-22	100.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,2TVDN@28211|Alphaproteobacteria,2K2S7@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_5230936_2	1283300.ATXB01000001_gene2242	6.842e-93	314.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S6JM@1236|Gammaproteobacteria,1XE76@135618|Methylococcales	135618|Methylococcales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
MMD2_k127_5230936_11	472759.Nhal_1509	5.94e-10	66.0	2AAM4@1|root,30ZYM@2|Bacteria,1RGIM@1224|Proteobacteria,1SETC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
MMD2_k127_5230936_3	234267.Acid_7681	1.284e-61	230.0	2DP3Z@1|root,32UK8@2|Bacteria,3Y581@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_527000_23	479432.Sros_4134	5.905e-41	166.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,4EJ5F@85012|Streptosporangiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMD2_k127_527000_18	246197.MXAN_6510	8.536e-54	194.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMD2_k127_527000_32	1121456.ATVA01000011_gene1529	1.738e-05	55.0	2DPQ4@1|root,332Y0@2|Bacteria,1N78P@1224|Proteobacteria,43DJQ@68525|delta/epsilon subdivisions,2X8QZ@28221|Deltaproteobacteria,2MD8T@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
MMD2_k127_527000_26	590998.Celf_0372	2.549e-27	113.0	COG3655@1|root,COG3655@2|Bacteria,2GQZM@201174|Actinobacteria,4F2Y5@85016|Cellulomonadaceae	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
MMD2_k127_527000_30	1261545.MBE-HAL_0567	7.175e-08	64.0	arCOG02709@1|root,arCOG02709@2157|Archaea,2XXZ2@28890|Euryarchaeota,23W35@183963|Halobacteria	183963|Halobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	glo2	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_527000_3	1121015.N789_10885	4.002e-125	412.0	COG1131@1|root,COG1835@1|root,COG1131@2|Bacteria,COG1835@2|Bacteria,1MUX3@1224|Proteobacteria,1SZAD@1236|Gammaproteobacteria,1XCV4@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Acyl_transf_3
MMD2_k127_527000_12	1122223.KB890688_gene1670	7.167e-80	273.0	COG2197@1|root,COG2197@2|Bacteria,1WM1U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
MMD2_k127_527000_17	240015.ACP_1073	3.86e-55	208.0	COG4585@1|root,COG4585@2|Bacteria,3Y42D@57723|Acidobacteria,2JHXY@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
MMD2_k127_527000_11	1123487.KB892865_gene1503	2.232e-83	293.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2VIRJ@28216|Betaproteobacteria,2KYJV@206389|Rhodocyclales	206389|Rhodocyclales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
MMD2_k127_527000_10	158500.BV97_01170	1.314e-93	327.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,2K23S@204457|Sphingomonadales	204457|Sphingomonadales	CH	FAD binding domain	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
MMD2_k127_527000_20	222534.KB893722_gene528	1.84e-47	182.0	COG4188@1|root,COG4188@2|Bacteria,2GMYW@201174|Actinobacteria	201174|Actinobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
MMD2_k127_527000_22	1123073.KB899241_gene3223	8.542e-43	169.0	28IZ5@1|root,2Z8WP@2|Bacteria,1R6WI@1224|Proteobacteria,1S87I@1236|Gammaproteobacteria,1X8SF@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_527000_19	1280950.HJO_02545	8.543e-52	199.0	COG3386@1|root,COG3386@2|Bacteria,1RHPS@1224|Proteobacteria,2UBD9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_527000_28	215803.DB30_0690	6.816e-18	88.0	2CC9P@1|root,331C0@2|Bacteria,1NEFX@1224|Proteobacteria,4385K@68525|delta/epsilon subdivisions,2X9Y9@28221|Deltaproteobacteria,2YVVB@29|Myxococcales	28221|Deltaproteobacteria	S	COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_527000_21	715451.ambt_12010	3.4e-43	177.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_527000_24	517418.Ctha_0623	2.27e-39	154.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2,TPR_16,TPR_19,TPR_2,TPR_8
MMD2_k127_527000_7	452637.Oter_1513	7.205e-106	356.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_527000_4	1396141.BATP01000042_gene1899	6.582e-119	394.0	COG0577@1|root,COG0577@2|Bacteria,46UQN@74201|Verrucomicrobia,2IVBP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_527000_2	1122604.JONR01000006_gene2746	1.202e-126	417.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,1X3ST@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrE	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMD2_k127_527000_8	1122604.JONR01000006_gene2747	1.068e-99	344.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,1X3CK@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	tptC	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_527000_27	861299.J421_1875	2.24e-25	110.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
MMD2_k127_527000_1	595460.RRSWK_04428	6.268e-141	452.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMD2_k127_527000_16	1116472.MGMO_112c00020	8.619e-58	219.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales	135618|Methylococcales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_527000_25	1101195.Meth11DRAFT_1447	1.692e-38	159.0	COG0607@1|root,COG3386@1|root,COG0607@2|Bacteria,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2VHGN@28216|Betaproteobacteria,2KNEV@206350|Nitrosomonadales	206350|Nitrosomonadales	GP	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMD2_k127_527000_15	627192.SLG_25140	3.212e-64	232.0	2EVK9@1|root,33P0C@2|Bacteria,1NDYB@1224|Proteobacteria,2UQHZ@28211|Alphaproteobacteria,2K9N4@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_527000_31	864069.MicloDRAFT_00057010	7.034e-06	55.0	2CBFC@1|root,32RYI@2|Bacteria,1N0T4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_527000_6	682795.AciX8_0859	9.547e-113	376.0	COG2706@1|root,COG2706@2|Bacteria,3Y75S@57723|Acidobacteria,2JKPU@204432|Acidobacteriia	204432|Acidobacteriia	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
MMD2_k127_527000_14	1532558.JL39_08595	4.169e-78	265.0	COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,2U5FW@28211|Alphaproteobacteria,4BA8V@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1348)	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
MMD2_k127_527000_13	536019.Mesop_1592	3.98e-78	265.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,43PV3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMD2_k127_527000_5	380358.XALC_0165	9.667e-114	374.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RTDE@1236|Gammaproteobacteria,1X5AI@135614|Xanthomonadales	135614|Xanthomonadales	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
MMD2_k127_527000_0	1123073.KB899243_gene698	4.582e-183	589.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQRJ@1236|Gammaproteobacteria,1X83S@135614|Xanthomonadales	135614|Xanthomonadales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
MMD2_k127_527000_9	1384056.N787_06630	1.438e-98	330.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,1T613@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
MMD2_k127_5391270_6	715451.ambt_12010	3.508e-56	212.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5391270_4	234267.Acid_3643	2.148e-94	336.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	LpoB,Sel1
MMD2_k127_5391270_0	1260251.SPISAL_05450	6.67e-237	742.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1WVVJ@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
MMD2_k127_5391270_1	243233.MCA0291	1.879e-233	736.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XESH@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
MMD2_k127_5391270_3	519989.ECTPHS_00685	4.894e-128	424.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
MMD2_k127_5391270_7	1254432.SCE1572_25680	3.772e-07	53.0	COG4636@1|root,COG4636@2|Bacteria,1Q8YX@1224|Proteobacteria,4344R@68525|delta/epsilon subdivisions,2X57Z@28221|Deltaproteobacteria,2Z08R@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
MMD2_k127_5391270_2	1121939.L861_05420	2.603e-131	428.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1XHTS@135619|Oceanospirillales	135619|Oceanospirillales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMD2_k127_5391270_5	234267.Acid_2214	1.311e-57	220.0	COG0577@1|root,COG0577@2|Bacteria,3Y6B8@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_5419734_4	1125973.JNLC01000002_gene2080	5.791e-93	314.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2TTSX@28211|Alphaproteobacteria,3JR0A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	MA20_15055	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
MMD2_k127_5419734_3	472759.Nhal_2148	9.015e-116	382.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,1RSFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
MMD2_k127_5419734_2	1144275.COCOR_04407	2.396e-133	434.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42MEY@68525|delta/epsilon subdivisions,2WM0F@28221|Deltaproteobacteria,2YXA9@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
MMD2_k127_5419734_12	1183438.GKIL_3929	8.418e-23	112.0	COG1228@1|root,COG1228@2|Bacteria,1G3PN@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD2_k127_5419734_11	1210884.HG799464_gene11143	6.093e-26	110.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMD2_k127_5419734_1	1340493.JNIF01000003_gene4672	8.782e-231	742.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_5419734_5	1267535.KB906767_gene4988	2.631e-76	276.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
MMD2_k127_5419734_6	1157708.KB907450_gene5321	4.943e-75	262.0	COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2VJ7W@28216|Betaproteobacteria,4ADUX@80864|Comamonadaceae	28216|Betaproteobacteria	P	extracellular solute-binding protein, family 1	-	-	5.3.3.7	ko:K22003	ko00660,map00660	-	R02244	RC00668	ko00000,ko00001,ko01000	-	-	-	SBP_bac_11
MMD2_k127_5419734_0	234267.Acid_2557	2.332e-281	882.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
MMD2_k127_5419734_8	627192.SLG_30730	1.086e-49	182.0	COG4922@1|root,COG4922@2|Bacteria,1RJ34@1224|Proteobacteria,2UT8H@28211|Alphaproteobacteria,2KBC2@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5419734_10	1082931.KKY_100	7.396e-32	132.0	2CBAE@1|root,34691@2|Bacteria,1N1N6@1224|Proteobacteria,2UD3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5419734_9	1082931.KKY_101	1.332e-47	176.0	2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2VCYT@28211|Alphaproteobacteria,3N96R@45401|Hyphomicrobiaceae	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5420342_29	396588.Tgr7_2922	4.977e-30	126.0	2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1WZKG@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4426
MMD2_k127_5420342_30	323261.Noc_3001	4.128e-28	120.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1WXC6@135613|Chromatiales	135613|Chromatiales	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
MMD2_k127_5420342_16	379731.PST_3966	1.303e-65	231.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1Z0N9@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
MMD2_k127_5420342_2	187272.Mlg_0342	8.28e-179	566.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMD2_k127_5420342_4	1122604.JONR01000015_gene102	4.895e-167	532.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1X4F6@135614|Xanthomonadales	135614|Xanthomonadales	NU	twitching motility protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
MMD2_k127_5420342_8	631362.Thi970DRAFT_02480	3.558e-130	424.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX4M@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMD2_k127_5420342_12	472759.Nhal_0207	9.909e-111	364.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,1RQ7W@1236|Gammaproteobacteria,1X286@135613|Chromatiales	135613|Chromatiales	C	Oxidoreductase FAD-binding domain	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind
MMD2_k127_5420342_33	391615.ABSJ01000042_gene2258	7.533e-21	101.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
MMD2_k127_5420342_20	1384054.N790_07705	5.42e-60	215.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1X41Z@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
MMD2_k127_5420342_28	396588.Tgr7_2909	6.354e-31	133.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,1X2IQ@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMD2_k127_5420342_6	519989.ECTPHS_03879	3.035e-130	424.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1WVY1@135613|Chromatiales	135613|Chromatiales	HJ	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
MMD2_k127_5420342_18	519989.ECTPHS_03874	2.021e-61	214.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1WY6S@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
MMD2_k127_5420342_25	314278.NB231_13331	4.809e-42	164.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1WYJQ@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
MMD2_k127_5420342_26	1123257.AUFV01000008_gene684	4.429e-34	143.0	COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1X6ZM@135614|Xanthomonadales	135614|Xanthomonadales	NT	Two component signalling adaptor domain	-	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
MMD2_k127_5420342_9	247633.GP2143_16411	7.54e-116	400.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1J59N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NT	COG0840 Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
MMD2_k127_5420342_1	935863.AWZR01000013_gene1458	2.089e-271	899.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales	135614|Xanthomonadales	T	Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
MMD2_k127_5420342_34	1123257.AUFV01000008_gene682	1.07e-19	95.0	COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,1X71Z@135614|Xanthomonadales	135614|Xanthomonadales	NT	Two component signalling adaptor domain	-	-	-	ko:K06598	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
MMD2_k127_5420342_23	743721.Psesu_2392	2.651e-49	185.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1X36H@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
MMD2_k127_5420342_15	1395571.TMS3_0119875	1.545e-70	243.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Negative regulator of beta-lactamase expression	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K01447,ko:K03806	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560	Amidase_2
MMD2_k127_5420342_17	767434.Fraau_0387	1.497e-63	228.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,1S40D@1236|Gammaproteobacteria,1X50D@135614|Xanthomonadales	135614|Xanthomonadales	S	adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
MMD2_k127_5420342_21	1122599.AUGR01000010_gene981	3.872e-56	207.0	28RZD@1|root,2ZEBA@2|Bacteria,1RBEH@1224|Proteobacteria,1RP8T@1236|Gammaproteobacteria,1XIH6@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5420342_11	1185876.BN8_01704	1.685e-112	398.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
MMD2_k127_5420342_24	1112214.AHIS01000081_gene3581	1.152e-48	181.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2K0J3@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
MMD2_k127_5420342_14	314278.NB231_06516	1.938e-103	344.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,1WXDM@135613|Chromatiales	135613|Chromatiales	S	Serine hydrolase involved in the detoxification of formaldehyde	-	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
MMD2_k127_5420342_7	502025.Hoch_6599	3.248e-130	425.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria,2YW0I@29|Myxococcales	28221|Deltaproteobacteria	E	Prephenate dehydrogenase chorismate mutase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
MMD2_k127_5420342_19	187272.Mlg_0427	3.296e-61	216.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1WXC4@135613|Chromatiales	135613|Chromatiales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
MMD2_k127_5420342_31	1415780.JPOG01000001_gene2828	4.275e-25	115.0	2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,1X665@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5420342_27	395493.BegalDRAFT_1306	5.529e-33	132.0	COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,461BH@72273|Thiotrichales	72273|Thiotrichales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMD2_k127_5420342_22	768671.ThimaDRAFT_0558	8.341e-51	182.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1WYPN@135613|Chromatiales	135613|Chromatiales	C	Iron--sulfur cluster insertion protein erpA	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
MMD2_k127_5420342_5	1260251.SPISAL_05890	2.701e-154	504.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1WWTY@135613|Chromatiales	135613|Chromatiales	FP	Belongs to the GppA Ppx family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
MMD2_k127_5420342_0	1335757.SPICUR_06640	8.574e-288	899.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1WXQF@135613|Chromatiales	135613|Chromatiales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
MMD2_k127_5420342_13	406817.XNC1_1886	5.741e-107	358.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032	AnmK
MMD2_k127_5420342_10	1123261.AXDW01000002_gene1513	5.05e-114	383.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1X3R2@135614|Xanthomonadales	135614|Xanthomonadales	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
MMD2_k127_5420342_3	1255043.TVNIR_3442	7.871e-178	566.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1WX6G@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
MMD2_k127_5420342_36	1382230.ASAP_2763	3.233e-11	65.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5420342_35	702113.PP1Y_AT36159	2.109e-13	69.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_542838_19	1085623.GNIT_3655	2.928e-39	151.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,4677J@72275|Alteromonadaceae	1236|Gammaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
MMD2_k127_542838_15	396588.Tgr7_0544	1.855e-56	203.0	2B4XH@1|root,31XQC@2|Bacteria,1RHJF@1224|Proteobacteria,1S3S1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_542838_6	420662.Mpe_A1224	1.611e-127	430.0	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,2VZB4@28216|Betaproteobacteria,1KN0Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_542838_1	420662.Mpe_A1225	4.228e-234	756.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,2VZ4H@28216|Betaproteobacteria,1KN47@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMD2_k127_542838_22	349521.HCH_02603	1.484e-28	125.0	COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,1XMRE@135619|Oceanospirillales	135619|Oceanospirillales	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_6,TPR_8
MMD2_k127_542838_25	864051.BurJ1DRAFT_1739	1.67e-14	80.0	2AHZN@1|root,318CZ@2|Bacteria,1Q06K@1224|Proteobacteria,2W4WA@28216|Betaproteobacteria,1KNW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_542838_12	396588.Tgr7_0539	4.294e-74	255.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1X07Q@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
MMD2_k127_542838_20	1049564.TevJSym_au00050	9.311e-32	130.0	COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,1JAY5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
MMD2_k127_542838_21	1049564.TevJSym_au00060	7.258e-30	125.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,1JAUR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
MMD2_k127_542838_17	1453501.JELR01000002_gene1323	3.004e-50	197.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_542838_5	1235457.C404_07105	4.299e-130	431.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2W004@28216|Betaproteobacteria,1K00Q@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	transporter	pcaK	-	-	ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4,Sugar_tr
MMD2_k127_542838_11	402881.Plav_1982	5.598e-76	263.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,1JNX0@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Inositol monophosphatase family	hisN	-	3.1.3.15,3.1.3.25,3.1.3.93	ko:K01092,ko:K18649	ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00114,M00131	R01185,R01186,R01187,R03013,R07674	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
MMD2_k127_542838_24	349102.Rsph17025_0944	2.79e-22	104.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,1FC34@1060|Rhodobacter	28211|Alphaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
MMD2_k127_542838_13	1230343.CANP01000021_gene1423	2.02e-67	244.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
MMD2_k127_542838_18	1005048.CFU_4161	4.72e-50	180.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,474CP@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
MMD2_k127_542838_2	1123073.KB899241_gene2530	2.312e-227	711.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1X39P@135614|Xanthomonadales	135614|Xanthomonadales	P	Ammonium transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMD2_k127_542838_8	247633.GP2143_10522	2.388e-96	322.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,1J6JA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
MMD2_k127_542838_26	1173021.ALWA01000036_gene3592	2.691e-11	72.0	2E6Y4@1|root,331HE@2|Bacteria,1GE1Z@1117|Cyanobacteria	1117|Cyanobacteria	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
MMD2_k127_542838_10	525904.Tter_0653	5.358e-81	288.0	COG1119@1|root,COG1119@2|Bacteria	2|Bacteria	P	ATPase activity	ylmA	-	3.6.3.34	ko:K02013,ko:K05776	ko02010,map02010	M00189,M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
MMD2_k127_542838_7	402881.Plav_2488	1.487e-97	329.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,1JN6A@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD2_k127_542838_0	1380394.JADL01000002_gene1193	0.0	1298.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2JQ67@204441|Rhodospirillales	204441|Rhodospirillales	C	COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
MMD2_k127_542838_23	1027273.GZ77_16035	4.926e-23	105.0	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,1SCNZ@1236|Gammaproteobacteria,1XMVA@135619|Oceanospirillales	135619|Oceanospirillales	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
MMD2_k127_542838_14	1210884.HG799465_gene11340	4.397e-62	226.0	COG1801@1|root,COG1801@2|Bacteria,2IYWM@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMD2_k127_542838_16	1123073.KB899242_gene948	2.604e-53	198.0	COG0457@1|root,COG0789@1|root,COG0457@2|Bacteria,COG0789@2|Bacteria,1NP3J@1224|Proteobacteria	1224|Proteobacteria	K	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
MMD2_k127_542838_9	861299.J421_5988	6.484e-85	290.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
MMD2_k127_542838_4	861299.J421_5987	3.974e-142	468.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria	2|Bacteria	L	DNA ligase (ATP) activity	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
MMD2_k127_542838_3	1232410.KI421426_gene1472	2.342e-177	574.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,43U0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
MMD2_k127_5429282_28	194867.ALBQ01000021_gene1962	7.165e-10	60.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,2K0CN@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17
MMD2_k127_5429282_6	1380394.JADL01000008_gene3739	6.946e-133	426.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,2JPYJ@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
MMD2_k127_5429282_27	631362.Thi970DRAFT_00483	4.221e-13	73.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1WZ6Q@135613|Chromatiales	135613|Chromatiales	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
MMD2_k127_5429282_15	187272.Mlg_1339	3.315e-75	258.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1WXBZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_5429282_31	1384056.N787_08625	6.585e-05	52.0	COG5662@1|root,COG5662@2|Bacteria,1NHTQ@1224|Proteobacteria,1T4A7@1236|Gammaproteobacteria,1XD9T@135614|Xanthomonadales	135614|Xanthomonadales	K	Anti sigma-E protein RseA, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RseA_N
MMD2_k127_5429282_18	187272.Mlg_1341	1.18e-52	204.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1WWVY@135613|Chromatiales	135613|Chromatiales	T	PFAM MucB RseB	-	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
MMD2_k127_5429282_29	1244869.H261_01262	1.474e-06	57.0	COG3086@1|root,COG3086@2|Bacteria,1Q49S@1224|Proteobacteria,2UMKW@28211|Alphaproteobacteria,2JXGZ@204441|Rhodospirillales	204441|Rhodospirillales	T	Positive regulator of sigma(E), RseC/MucC	-	-	-	-	-	-	-	-	-	-	-	-	RseC_MucC
MMD2_k127_5429282_26	1123368.AUIS01000017_gene2574	9.827e-14	78.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	DUF836,Thioredoxin,Thioredoxin_3,TraF
MMD2_k127_5429282_0	243233.MCA1466	6.3e-239	747.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1XE1C@135618|Methylococcales	135618|Methylococcales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
MMD2_k127_5429282_22	935567.JAES01000030_gene2874	2.554e-38	144.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1X3UI@135614|Xanthomonadales	135614|Xanthomonadales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
MMD2_k127_5429282_13	323261.Noc_2460	2.185e-80	276.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1WXAU@135613|Chromatiales	135613|Chromatiales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
MMD2_k127_5429282_30	1123261.AXDW01000024_gene2077	1.106e-05	55.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
MMD2_k127_5429282_17	713586.KB900536_gene174	2.638e-55	206.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1WY7U@135613|Chromatiales	135613|Chromatiales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
MMD2_k127_5429282_16	1231391.AMZF01000030_gene316	1.146e-72	255.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,3T2HN@506|Alcaligenaceae	28216|Betaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
MMD2_k127_5429282_21	105559.Nwat_2316	2.848e-45	180.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1WY02@135613|Chromatiales	135613|Chromatiales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
MMD2_k127_5429282_12	1123368.AUIS01000017_gene2581	6.869e-92	314.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,2NBRG@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
MMD2_k127_5429282_24	28258.KP05_02470	6.16e-22	108.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XKU7@135619|Oceanospirillales	135619|Oceanospirillales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
MMD2_k127_5429282_11	393595.ABO_1625	9.535e-99	329.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,1S4HU@1236|Gammaproteobacteria,1XNB9@135619|Oceanospirillales	135619|Oceanospirillales	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
MMD2_k127_5429282_7	1500893.JQNB01000001_gene2359	6.254e-129	425.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1X4IP@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
MMD2_k127_5429282_19	1380394.JADL01000010_gene4296	4.047e-48	186.0	COG3386@1|root,COG3386@2|Bacteria,1RHPS@1224|Proteobacteria,2UBD9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5429282_2	702113.PP1Y_AT5335	5.569e-153	497.0	COG0477@1|root,COG2814@2|Bacteria,1R1JD@1224|Proteobacteria	1224|Proteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_5429282_3	702113.PP1Y_AT5354	2.257e-148	475.0	COG2513@1|root,COG2513@2|Bacteria,1NSNW@1224|Proteobacteria,2UQIU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
MMD2_k127_5429282_9	702113.PP1Y_AT5275	1.221e-112	371.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TTJV@28211|Alphaproteobacteria,2K0IQ@204457|Sphingomonadales	204457|Sphingomonadales	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMD2_k127_5429282_8	702113.PP1Y_AT5282	4.305e-116	378.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TTVF@28211|Alphaproteobacteria,2KCN5@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
MMD2_k127_5429282_5	702113.PP1Y_AT5290	1.07e-134	434.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,2KCXY@204457|Sphingomonadales	204457|Sphingomonadales	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.264	ko:K00098	-	-	R05684	RC00089	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_5429282_25	702113.PP1Y_AT5290	2.461e-15	76.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,2KCXY@204457|Sphingomonadales	204457|Sphingomonadales	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.264	ko:K00098	-	-	R05684	RC00089	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_5429282_23	702113.PP1Y_AT5302	2.949e-38	148.0	2C5AZ@1|root,32RFC@2|Bacteria,1RKP0@1224|Proteobacteria,2UD51@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5429282_4	702113.PP1Y_AT5306	7.445e-143	462.0	COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,2TQM4@28211|Alphaproteobacteria,2KAB0@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K06145	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
MMD2_k127_5429282_10	702113.PP1Y_AT5321	2.102e-110	378.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2U255@28211|Alphaproteobacteria,2K2X3@204457|Sphingomonadales	204457|Sphingomonadales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMD2_k127_5429282_20	702113.PP1Y_AT5326	1.757e-47	188.0	COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,2UBQX@28211|Alphaproteobacteria,2K4M0@204457|Sphingomonadales	204457|Sphingomonadales	G	Gluconokinase	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_33,SKI
MMD2_k127_5429282_1	1121335.Clst_2416	5.216e-204	645.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,248YA@186801|Clostridia	186801|Clostridia	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
MMD2_k127_5429282_14	247633.GP2143_14311	4.703e-76	262.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria,1JAB2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3202 ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
MMD2_k127_5443585_16	627192.SLG_20120	7.569e-80	270.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,2U189@28211|Alphaproteobacteria,2K4PZ@204457|Sphingomonadales	204457|Sphingomonadales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMD2_k127_5443585_6	627192.SLG_20170	1.181e-164	534.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2K0FF@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the GMC oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
MMD2_k127_5443585_11	627192.SLG_20160	3.837e-100	338.0	COG0491@1|root,COG0491@2|Bacteria,1N22F@1224|Proteobacteria,2U2V5@28211|Alphaproteobacteria,2K3EH@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_5443585_9	452637.Oter_1501	3.186e-102	354.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
MMD2_k127_5443585_8	452637.Oter_1502	5.68e-118	385.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,3K7BH@414999|Opitutae	2|Bacteria	V	PFAM ABC transporter related	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_5443585_34	105425.BBPL01000074_gene3840	5.958e-30	135.0	COG2020@1|root,COG2020@2|Bacteria,2HUDA@201174|Actinobacteria,2NIQ9@228398|Streptacidiphilus	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMD2_k127_5443585_14	1122604.JONR01000007_gene2936	1.327e-89	322.0	28P4Q@1|root,2ZBZV@2|Bacteria,1RA48@1224|Proteobacteria,1S347@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5443585_40	886293.Sinac_4805	2.901e-05	56.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,DUF1080,DUF4394,PKD,SdrD_B
MMD2_k127_5443585_35	1122604.JONR01000007_gene2935	1.736e-27	127.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
MMD2_k127_5443585_13	1050202.KB913024_gene1462	1.906e-96	332.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,4084I@622450|Actinopolysporales	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE2	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMD2_k127_5443585_29	925775.XVE_4090	1.81e-43	166.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,1SC6Q@1236|Gammaproteobacteria,1X520@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE4	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
MMD2_k127_5443585_36	382464.ABSI01000010_gene3557	6.591e-21	100.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMD2_k127_5443585_7	1123487.KB892835_gene3313	1.075e-126	437.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VIXC@28216|Betaproteobacteria,2M02Y@206389|Rhodocyclales	28216|Betaproteobacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_3_2,Big_3_3,Peptidase_S8
MMD2_k127_5443585_3	1385511.N783_00010	6.916e-209	671.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli	91061|Bacilli	CG	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_5443585_32	1126627.BAWE01000004_gene2305	5.125e-32	139.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria,3JUHX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_5443585_5	886293.Sinac_1153	9.47e-175	589.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_5443585_12	1340493.JNIF01000003_gene1475	2.048e-99	338.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_5443585_23	627192.SLG_31390	1.725e-61	234.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
MMD2_k127_5443585_30	234267.Acid_1337	4.554e-37	151.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
MMD2_k127_5443585_21	1122604.JONR01000013_gene3226	2.197e-65	232.0	2DMPM@1|root,32SWT@2|Bacteria,1REC9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5443585_10	83406.HDN1F_09510	2.1e-101	352.0	28I8G@1|root,2Z8BA@2|Bacteria,1MWYF@1224|Proteobacteria,1RTN9@1236|Gammaproteobacteria,1J8V5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
MMD2_k127_5443585_1	765912.Thimo_0713	1.013e-233	767.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1WW3V@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
MMD2_k127_5443585_22	634500.EbC_02380	2.846e-65	231.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,3X5AD@551|Erwinia	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
MMD2_k127_5443585_18	1336235.JAEG01000009_gene2646	3.572e-75	257.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VG84@28211|Alphaproteobacteria,4B8Y9@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
MMD2_k127_5443585_27	234267.Acid_4171	2.774e-48	184.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_5443585_20	404589.Anae109_0028	1.636e-67	246.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,4383U@68525|delta/epsilon subdivisions,2X3DT@28221|Deltaproteobacteria,2YVM7@29|Myxococcales	28221|Deltaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD2_k127_5443585_17	987059.RBXJA2T_13269	4.528e-78	266.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria,1KKKC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
MMD2_k127_5443585_15	1000565.METUNv1_02775	6.05e-88	293.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria,2KVCY@206389|Rhodocyclales	206389|Rhodocyclales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
MMD2_k127_5443585_19	1123261.AXDW01000009_gene101	1.579e-68	244.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,1XC3C@135614|Xanthomonadales	135614|Xanthomonadales	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
MMD2_k127_5443585_28	709797.CSIRO_1398	9.984e-45	167.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,3JUPW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	TPM domain	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
MMD2_k127_5443585_4	251221.35213197	4.124e-191	630.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
MMD2_k127_5443585_24	1123247.AUIJ01000001_gene1778	3.89e-59	214.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
MMD2_k127_5443585_0	1121935.AQXX01000131_gene2793	7.71e-253	793.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XIWM@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA helicase	recQ1	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
MMD2_k127_5443585_37	627192.SLG_09880	1.483e-13	80.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5443585_26	754476.Q7A_1942	9.142e-57	200.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S7KX@1236|Gammaproteobacteria,463K7@72273|Thiotrichales	72273|Thiotrichales	S	protein conserved in bacteria	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
MMD2_k127_5443585_2	234267.Acid_3236	4.985e-209	674.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
MMD2_k127_5443585_31	1239962.C943_00079	9.574e-33	136.0	COG5395@1|root,COG5395@2|Bacteria,4NSVW@976|Bacteroidetes	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
MMD2_k127_5443585_33	247633.GP2143_17796	5.572e-30	133.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5443585_39	555793.WSK_2874	4.843e-11	70.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5509297_6	94624.Bpet3498	3.314e-97	347.0	COG0715@1|root,COG0715@2|Bacteria,1MWJF@1224|Proteobacteria,2VKCQ@28216|Betaproteobacteria,3T92X@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
MMD2_k127_5509297_2	1218074.BAXZ01000004_gene991	7.398e-166	533.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VN65@28216|Betaproteobacteria,1K3BE@119060|Burkholderiaceae	28216|Betaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMD2_k127_5509297_3	1403819.BATR01000069_gene2061	4.822e-140	454.0	COG4447@1|root,COG4447@2|Bacteria,46X9A@74201|Verrucomicrobia,2IV3H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5509297_11	1340493.JNIF01000004_gene1068	8.588e-20	92.0	COG1977@1|root,COG1977@2|Bacteria,3Y910@57723|Acidobacteria	57723|Acidobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5509297_7	1278073.MYSTI_00409	1.446e-79	292.0	2C1VH@1|root,2Z7Z3@2|Bacteria,1MY5B@1224|Proteobacteria	1224|Proteobacteria	S	3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase	wbxY	-	-	-	-	-	-	-	-	-	-	-	Kdo_hydroxy
MMD2_k127_5509297_5	1266909.AUAG01000001_gene1479	2.153e-117	400.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1X2HB@135613|Chromatiales	135613|Chromatiales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMD2_k127_5509297_10	1131553.JIBI01000004_gene400	1.721e-32	129.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,3735G@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
MMD2_k127_5509297_4	1198452.Jab_2c00930	4.715e-118	387.0	COG0583@1|root,COG0583@2|Bacteria,1MV06@1224|Proteobacteria,2VHGD@28216|Betaproteobacteria,473DX@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K18900	-	M00698	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	HTH_1,LysR_substrate
MMD2_k127_5509297_8	243365.CV_0435	5.216e-79	279.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,2KPHI@206351|Neisseriales	206351|Neisseriales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
MMD2_k127_5509297_0	1121004.ATVC01000042_gene944	0.0	1150.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KPEV@206351|Neisseriales	206351|Neisseriales	V	Efflux pump membrane transporter	mtrD	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
MMD2_k127_5509297_1	59538.XP_005968334.1	2.351e-189	597.0	COG1960@1|root,KOG0139@2759|Eukaryota,38H6J@33154|Opisthokonta,3BC6X@33208|Metazoa,3CVK7@33213|Bilateria,489NE@7711|Chordata,48VKC@7742|Vertebrata,3J1K7@40674|Mammalia,4J3Z3@91561|Cetartiodactyla	59538.XP_005968334.1|-	I	Short branched chain specific acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5509297_9	401053.AciPR4_0837	2.521e-57	217.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMD2_k127_5509297_12	136273.GY22_12035	4.603e-06	53.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,1W8SE@1268|Micrococcaceae	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMD2_k127_5530062_14	614083.AWQR01000022_gene74	1.093e-53	192.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2VJXA@28216|Betaproteobacteria,4AB8B@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM amidohydrolase 2	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMD2_k127_5530062_2	1244869.H261_12086	9.486e-230	732.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2JPNR@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
MMD2_k127_5530062_13	935863.AWZR01000001_gene1895	1.838e-58	209.0	COG1309@1|root,COG1309@2|Bacteria,1N6P0@1224|Proteobacteria,1T8W9@1236|Gammaproteobacteria,1XBBH@135614|Xanthomonadales	135614|Xanthomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMD2_k127_5530062_15	1101191.KI912577_gene1475	6.03e-53	196.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria,1JQR8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	-
MMD2_k127_5530062_0	1500890.JQNL01000001_gene2476	3.367e-311	964.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1X3IX@135614|Xanthomonadales	135614|Xanthomonadales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
MMD2_k127_5530062_3	472759.Nhal_0506	1.017e-211	664.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1WWG7@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
MMD2_k127_5530062_10	472759.Nhal_0505	2.615e-78	267.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMD2_k127_5530062_11	519989.ECTPHS_09233	8.524e-69	247.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1WZ40@135613|Chromatiales	135613|Chromatiales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
MMD2_k127_5530062_19	857087.Metme_0227	3.034e-10	68.0	2DRM4@1|root,33C8W@2|Bacteria,1NQ8K@1224|Proteobacteria,1SGVH@1236|Gammaproteobacteria,1XFRG@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5530062_5	396588.Tgr7_2447	2.657e-169	552.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1WWVU@135613|Chromatiales	135613|Chromatiales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMD2_k127_5530062_17	519989.ECTPHS_02314	1.262e-43	166.0	COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1SAAZ@1236|Gammaproteobacteria,1WXGU@135613|Chromatiales	135613|Chromatiales	S	peptidase S16, lon	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
MMD2_k127_5530062_18	472759.Nhal_3763	2.326e-25	105.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,1SC8Q@1236|Gammaproteobacteria,1WZ6V@135613|Chromatiales	135613|Chromatiales	C	PFAM Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
MMD2_k127_5530062_16	325777.GW15_0210700	1.234e-49	197.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1X5HS@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
MMD2_k127_5530062_12	314278.NB231_13481	1.699e-66	237.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1WXST@135613|Chromatiales	135613|Chromatiales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
MMD2_k127_5530062_1	765914.ThisiDRAFT_1528	3.674e-274	862.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1WVWH@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
MMD2_k127_5530062_4	1384056.N787_04430	7.066e-172	546.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1X34S@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
MMD2_k127_5530062_7	930169.B5T_00265	6.613e-155	499.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1XH3J@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
MMD2_k127_5530062_9	1121033.AUCF01000030_gene209	2.337e-110	376.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2TQJY@28211|Alphaproteobacteria,2JQ50@204441|Rhodospirillales	204441|Rhodospirillales	G	Domain of unknown function (DUF4147)	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
MMD2_k127_5530062_6	396588.Tgr7_2890	2.858e-163	529.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales	135613|Chromatiales	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
MMD2_k127_5530062_8	187272.Mlg_1761	9.487e-119	394.0	COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,1WYC3@135613|Chromatiales	135613|Chromatiales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMD2_k127_5538116_0	713587.THITH_05400	3.246e-319	999.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1WWFC@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297	ko00071,ko00910,ko01120,map00071,map00910,map01120	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
MMD2_k127_5538116_9	551275.KB899545_gene2986	6.967e-111	372.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,2U1FE@28211|Alphaproteobacteria,43WDC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
MMD2_k127_5538116_2	716928.AJQT01000039_gene1468	1.089e-246	773.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,4BAAI@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC transporter	-	-	-	ko:K02049,ko:K15555,ko:K15578	ko00910,ko00920,ko02010,map00910,map00920,map02010	M00188,M00436,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
MMD2_k127_5538116_7	1244869.H261_07463	6.231e-141	456.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2TQT6@28211|Alphaproteobacteria,2JR63@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050,ko:K15577	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	BPD_transp_1
MMD2_k127_5538116_3	1244869.H261_07458	6.945e-225	715.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria,2JQF7@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K15576,ko:K22067	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
MMD2_k127_5538116_10	1267005.KB911257_gene966	9.393e-97	329.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	nrt	-	-	ko:K15576,ko:K22067	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
MMD2_k127_5538116_13	1211115.ALIQ01000002_gene4358	3.609e-64	241.0	COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2U220@28211|Alphaproteobacteria,3NB3Y@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	ANTAR	nasT	-	-	ko:K07183	-	-	-	-	ko00000,ko02022	-	-	-	ANTAR,Response_reg
MMD2_k127_5538116_12	215803.DB30_2118	2.574e-78	273.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria,42ZUS@68525|delta/epsilon subdivisions,2WVEB@28221|Deltaproteobacteria,2YZB9@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_5538116_11	215803.DB30_2117	1.024e-79	281.0	COG1252@1|root,COG1252@2|Bacteria,1N2QQ@1224|Proteobacteria,438MS@68525|delta/epsilon subdivisions,2X3VZ@28221|Deltaproteobacteria,2YV5Z@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
MMD2_k127_5538116_4	1333998.M2A_2722	1.244e-207	655.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2TQUS@28211|Alphaproteobacteria,4BRU9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
MMD2_k127_5538116_8	215803.DB30_5068	1.388e-128	423.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42QJX@68525|delta/epsilon subdivisions,2WKPN@28221|Deltaproteobacteria,2Z26U@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMD2_k127_5538116_1	631454.N177_2724	1.373e-299	945.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,1JN4S@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMD2_k127_5538116_16	1247963.JPHU01000004_gene470	5.856e-50	190.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	dehydratase	nodN	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMD2_k127_5538116_6	1123060.JONP01000003_gene330	1.046e-146	486.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2TQT2@28211|Alphaproteobacteria,2JQWK@204441|Rhodospirillales	204441|Rhodospirillales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMD2_k127_5538116_5	595536.ADVE02000002_gene4230	3.144e-156	505.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,36YN6@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
MMD2_k127_5538116_15	977880.RALTA_B1994	1.111e-54	199.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2VRNU@28216|Betaproteobacteria,1KG4I@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_5538116_14	913325.N799_01025	3.41e-61	224.0	COG1639@1|root,COG1639@2|Bacteria,1R4X1@1224|Proteobacteria,1RYJJ@1236|Gammaproteobacteria,1X6MI@135614|Xanthomonadales	135614|Xanthomonadales	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
MMD2_k127_5571499_2	269799.Gmet_2580	7.459e-241	754.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42P3V@68525|delta/epsilon subdivisions,2WKWV@28221|Deltaproteobacteria,43TF0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMD2_k127_5571499_27	1449065.JMLL01000011_gene2151	0.0001504	52.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2UCD8@28211|Alphaproteobacteria,43KE9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
MMD2_k127_5571499_21	62928.azo2600	1.225e-19	94.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VHFY@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD2_k127_5571499_16	234267.Acid_1337	7.651e-53	197.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
MMD2_k127_5571499_13	1380355.JNIJ01000025_gene1187	4.161e-78	270.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,3JRP5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	MA20_37085	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMD2_k127_5571499_4	1267535.KB906767_gene2430	7.155e-199	643.0	COG4993@1|root,COG4993@2|Bacteria,3Y6BH@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
MMD2_k127_5571499_24	589924.Ferp_0363	2.366e-12	74.0	COG0071@1|root,arCOG01832@2157|Archaea,2XYW4@28890|Euryarchaeota,246BR@183980|Archaeoglobi	183980|Archaeoglobi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMD2_k127_5571499_12	1038860.AXAP01000023_gene7385	4.645e-97	330.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TU4F@28211|Alphaproteobacteria,3JQPK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	FMN-dependent dehydrogenase	MA20_37755	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FMN_dh
MMD2_k127_5571499_10	483219.LILAB_16345	1.234e-117	414.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,42PBU@68525|delta/epsilon subdivisions,2WKE2@28221|Deltaproteobacteria,2YTT8@29|Myxococcales	28221|Deltaproteobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
MMD2_k127_5571499_8	765910.MARPU_00780	3.099e-143	477.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,1RRKZ@1236|Gammaproteobacteria,1WWQA@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
MMD2_k127_5571499_28	9978.XP_004590684.1	0.0008612	50.0	KOG1695@1|root,KOG1695@2759|Eukaryota,39R3B@33154|Opisthokonta,3BJH6@33208|Metazoa,3D3HE@33213|Bilateria,482XR@7711|Chordata,48YR3@7742|Vertebrata,3J8I2@40674|Mammalia,35G2V@314146|Euarchontoglires	33208|Metazoa	O	prostaglandin-D synthase activity	HPGDS	GO:0000287,GO:0001516,GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0004667,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006518,GO:0006575,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0006749,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008285,GO:0008610,GO:0009058,GO:0009636,GO:0009987,GO:0016053,GO:0016209,GO:0016491,GO:0016684,GO:0016740,GO:0016765,GO:0016853,GO:0016860,GO:0019752,GO:0032787,GO:0033559,GO:0034641,GO:0042127,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043900,GO:0043901,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046456,GO:0046457,GO:0046872,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051239,GO:0051241,GO:0051716,GO:0055114,GO:0065007,GO:0070887,GO:0071704,GO:0072330,GO:0097237,GO:0098754,GO:0098869,GO:1901564,GO:1901568,GO:1901570,GO:1901576,GO:1905936,GO:1905937,GO:1990748,GO:2000241,GO:2000242,GO:2000254,GO:2000255	2.5.1.18,5.3.99.2	ko:K04097	ko00480,ko00590,ko00980,ko00982,ko01100,ko05204,map00480,map00590,map00980,map00982,map01100,map05204	-	R02266,R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409	RC00004,RC00069,RC00672,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000	-	-	-	GST_C_3,GST_N
MMD2_k127_5571499_9	1232683.ADIMK_0084	5.093e-136	454.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
MMD2_k127_5571499_11	1380391.JIAS01000013_gene3736	4.984e-107	361.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,2JPKF@204441|Rhodospirillales	204441|Rhodospirillales	M	COG3264 Small-conductance mechanosensitive channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	DUF3772,MS_channel
MMD2_k127_5571499_15	913325.N799_03225	3.257e-57	207.0	COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,1RNIQ@1236|Gammaproteobacteria,1X4WS@135614|Xanthomonadales	135614|Xanthomonadales	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
MMD2_k127_5571499_3	570952.ATVH01000002_gene950	1.604e-232	736.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2TRMQ@28211|Alphaproteobacteria,2JQKZ@204441|Rhodospirillales	204441|Rhodospirillales	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
MMD2_k127_5571499_7	414684.RC1_3515	1.414e-149	488.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,2JPVA@204441|Rhodospirillales	204441|Rhodospirillales	G	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
MMD2_k127_5571499_18	1121921.KB898706_gene2722	5.376e-38	154.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,2PNZB@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	NU	Pilin (bacterial filament)	pilA	-	-	ko:K02650,ko:K02655	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
MMD2_k127_5571499_26	323261.Noc_1689	9.772e-08	61.0	2EB0T@1|root,3351P@2|Bacteria,1NCHM@1224|Proteobacteria,1SJ6Z@1236|Gammaproteobacteria,1X1WX@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5571499_17	314345.SPV1_12982	2.939e-39	150.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria	1224|Proteobacteria	P	arsenate reductase	arsC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
MMD2_k127_5571499_5	1095769.CAHF01000010_gene1161	1.367e-189	623.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,473KS@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,cNMP_binding
MMD2_k127_5571499_14	84531.JMTZ01000012_gene2947	4.076e-59	215.0	29M6H@1|root,3083Y@2|Bacteria,1RJTC@1224|Proteobacteria,1T7NK@1236|Gammaproteobacteria,1X9GZ@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5571499_23	1229172.JQFA01000005_gene89	4.508e-14	80.0	2DIJ1@1|root,303EZ@2|Bacteria,1GDQS@1117|Cyanobacteria,1HFPY@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5571499_25	1379270.AUXF01000004_gene3193	7.282e-10	68.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
MMD2_k127_5571499_20	450851.PHZ_c3077	1.039e-31	139.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5571499_6	1380394.JADL01000011_gene3844	2.981e-150	491.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2TT6V@28211|Alphaproteobacteria,2JPWF@204441|Rhodospirillales	204441|Rhodospirillales	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
MMD2_k127_5571499_0	768671.ThimaDRAFT_4419	0.0	1119.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WWTA@135613|Chromatiales	135613|Chromatiales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMD2_k127_5571499_19	1123269.NX02_24625	3.977e-33	135.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2UC33@28211|Alphaproteobacteria,2K5EE@204457|Sphingomonadales	204457|Sphingomonadales	P	Nitrite reductase	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
MMD2_k127_5571499_1	545264.KB898753_gene1709	4.092e-300	926.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1WWFC@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297	ko00071,ko00910,ko01120,map00071,map00910,map01120	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
MMD2_k127_5582097_5	629773.AORY01000005_gene2660	4.792e-22	108.0	COG2207@1|root,COG2207@2|Bacteria,1MXT9@1224|Proteobacteria,2U0UP@28211|Alphaproteobacteria,2K7AB@204457|Sphingomonadales	204457|Sphingomonadales	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
MMD2_k127_5582097_3	398579.Spea_3950	2.049e-59	224.0	2B9C3@1|root,322PT@2|Bacteria,1NTUZ@1224|Proteobacteria,1SMH9@1236|Gammaproteobacteria,2QBH3@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5582097_0	1082931.KKY_2582	4.444e-207	661.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
MMD2_k127_5582097_2	381666.H16_B0430	1.059e-77	275.0	COG2271@1|root,COG2271@2|Bacteria,1R3QT@1224|Proteobacteria,2VKW2@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_5582097_1	1082931.KKY_2582	2.457e-196	628.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
MMD2_k127_5582097_4	518766.Rmar_1911	1.007e-23	106.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
MMD2_k127_5582097_6	627192.SLG_09880	2.503e-18	96.0	28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5584097_19	292415.Tbd_1125	1.213e-57	203.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,1KS1U@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Dihydrodipicolinate reductase, C-terminus	-	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
MMD2_k127_5584097_7	1121935.AQXX01000067_gene5845	4.535e-168	535.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XHDH@135619|Oceanospirillales	135619|Oceanospirillales	F	carbamoyl-phosphate synthetase glutamine chain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
MMD2_k127_5584097_0	396588.Tgr7_0977	0.0	1562.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales	135613|Chromatiales	EF	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
MMD2_k127_5584097_18	765914.ThisiDRAFT_1999	4.284e-62	219.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1WY5U@135613|Chromatiales	135613|Chromatiales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
MMD2_k127_5584097_17	1266908.AQPB01000045_gene915	1.953e-62	220.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1WX98@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
MMD2_k127_5584097_1	396588.Tgr7_0981	7.272e-304	945.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales	135613|Chromatiales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMD2_k127_5584097_8	1116472.MGMO_88c00330	2.153e-164	529.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1XEX8@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMD2_k127_5584097_12	396588.Tgr7_0984	7.367e-86	291.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1WW6U@135613|Chromatiales	135613|Chromatiales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
MMD2_k127_5584097_22	1123261.AXDW01000001_gene1230	3.036e-19	94.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1X70B@135614|Xanthomonadales	135614|Xanthomonadales	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
MMD2_k127_5584097_20	1123401.JHYQ01000005_gene294	2.004e-47	174.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,460WP@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
MMD2_k127_5584097_11	1158165.KB898872_gene1066	1.402e-90	306.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMD2_k127_5584097_13	1260251.SPISAL_03105	1.968e-77	275.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,1WWDD@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
MMD2_k127_5584097_3	1469245.JFBG01000086_gene1625	2.102e-249	772.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
MMD2_k127_5584097_15	1469245.JFBG01000086_gene1624	8.678e-71	245.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMD2_k127_5584097_6	396588.Tgr7_0991	1.403e-198	626.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1WWH3@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMD2_k127_5584097_4	396588.Tgr7_0992	8.476e-230	736.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMD2_k127_5584097_10	1123400.KB904758_gene2390	1.104e-139	485.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,45ZQ9@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
MMD2_k127_5584097_14	396588.Tgr7_0994	1.26e-76	259.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria,1WWN9@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
MMD2_k127_5584097_16	1123393.KB891327_gene385	4.046e-63	222.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,1KS7Z@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
MMD2_k127_5584097_21	1255043.TVNIR_3116	3.503e-36	149.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,1WYHG@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMD2_k127_5584097_2	1026882.MAMP_00775	6.842e-277	865.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,45ZMF@72273|Thiotrichales	72273|Thiotrichales	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
MMD2_k127_5584097_5	765912.Thimo_0597	8.835e-228	714.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1WXM2@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
MMD2_k127_5584097_9	396588.Tgr7_0999	3.138e-164	529.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMD2_k127_5584097_23	202952.BBLI01000003_gene293	7.086e-10	61.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria,3NQGN@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5593623_33	1123368.AUIS01000003_gene1841	2.047e-23	103.0	COG4783@1|root,COG4783@2|Bacteria,1N76P@1224|Proteobacteria,1T4CE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMD2_k127_5593623_31	395492.Rleg2_2264	4.648e-33	131.0	COG5605@1|root,COG5605@2|Bacteria,1RH8B@1224|Proteobacteria,2U9FI@28211|Alphaproteobacteria,4BFM4@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Small integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
MMD2_k127_5593623_11	1095769.CAHF01000013_gene3384	2.73e-110	360.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VKKS@28216|Betaproteobacteria,473Y3@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
MMD2_k127_5593623_23	1054213.HMPREF9946_00804	4.49e-58	209.0	COG1845@1|root,COG1845@2|Bacteria,1MXAB@1224|Proteobacteria,2TRFQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c oxidase, subunit III	coxO	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
MMD2_k127_5593623_1	247634.GPB2148_122	8.244e-307	947.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RNUX@1236|Gammaproteobacteria,1J7MA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
MMD2_k127_5593623_4	1121374.KB891577_gene3209	5.486e-168	539.0	COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,1RY2R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
MMD2_k127_5593623_29	745411.B3C1_04630	2.614e-44	165.0	COG3241@1|root,COG3241@2|Bacteria,1RHV2@1224|Proteobacteria,1S6H8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Transfers electrons from cytochrome c551 to cytochrome oxidase	azu	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
MMD2_k127_5593623_26	1279015.KB908459_gene2699	4.972e-49	179.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1Y4IF@135624|Aeromonadales	135624|Aeromonadales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
MMD2_k127_5593623_38	765912.Thimo_1850	8.086e-13	75.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1WZ7B@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMD2_k127_5593623_37	393595.ABO_2251	5.588e-13	74.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1XM56@135619|Oceanospirillales	135619|Oceanospirillales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMD2_k127_5593623_16	243924.LT42_18965	2.152e-84	287.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
MMD2_k127_5593623_3	472759.Nhal_3091	1.44e-217	699.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1WXBI@135613|Chromatiales	135613|Chromatiales	S	oligopeptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
MMD2_k127_5593623_5	1001585.MDS_3760	4.878e-147	482.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1YESF@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Aminotransferase class-V	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_5593623_27	243233.MCA2602	7.815e-47	178.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XEWA@135618|Methylococcales	135618|Methylococcales	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA
MMD2_k127_5593623_22	870187.Thini_3153	2.421e-59	214.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,460ST@72273|Thiotrichales	72273|Thiotrichales	C	PFAM cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_5593623_24	713586.KB900536_gene2342	2.064e-52	193.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1WWX9@135613|Chromatiales	135613|Chromatiales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
MMD2_k127_5593623_0	713586.KB900536_gene2217	0.0	1138.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales	135613|Chromatiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
MMD2_k127_5593623_12	448385.sce1759	5.839e-94	323.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales	28221|Deltaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
MMD2_k127_5593623_18	1144275.COCOR_02389	3.509e-74	259.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
MMD2_k127_5593623_20	518766.Rmar_0946	2.337e-65	235.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1FJUC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMD2_k127_5593623_13	1121920.AUAU01000010_gene42	1.342e-88	305.0	COG4992@1|root,COG4992@2|Bacteria,3Y36P@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMD2_k127_5593623_28	1123008.KB905694_gene1704	1.67e-44	184.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,2FMWZ@200643|Bacteroidia,22WTC@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMD2_k127_5593623_15	246197.MXAN_5109	4.32e-85	295.0	COG0132@1|root,COG0132@2|Bacteria,1MYAE@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611
MMD2_k127_5593623_10	518766.Rmar_0950	6.125e-114	388.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1FJVB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
MMD2_k127_5593623_34	204669.Acid345_4162	4.657e-19	99.0	COG1438@1|root,COG1438@2|Bacteria,3Y551@57723|Acidobacteria,2JJTA@204432|Acidobacteriia	204432|Acidobacteriia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
MMD2_k127_5593623_17	666685.R2APBS1_0116	1.728e-79	274.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1X4YF@135614|Xanthomonadales	135614|Xanthomonadales	S	Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
MMD2_k127_5593623_25	243231.GSU0792	3.185e-51	190.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,42QS8@68525|delta/epsilon subdivisions,2WMV7@28221|Deltaproteobacteria,43SGZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
MMD2_k127_5593623_40	631362.Thi970DRAFT_00343	0.0007529	49.0	2DSD0@1|root,33FKD@2|Bacteria,1NIYS@1224|Proteobacteria,1SWRT@1236|Gammaproteobacteria,1X1QA@135613|Chromatiales	135613|Chromatiales	N	PFAM Flagellar transcriptional activator (FlhC)	-	-	-	-	-	-	-	-	-	-	-	-	FlhC
MMD2_k127_5593623_8	1122201.AUAZ01000015_gene733	6.765e-121	406.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,465BH@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	COG1131 ABC-type multidrug transport system, ATPase component	yadG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_5593623_14	454957.IA64_00715	3.446e-88	301.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1X38I@135614|Xanthomonadales	135614|Xanthomonadales	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMD2_k127_5593623_21	1123368.AUIS01000006_gene572	2.631e-62	221.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,2NCEE@225057|Acidithiobacillales	225057|Acidithiobacillales	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
MMD2_k127_5593623_36	1121013.P873_09000	1.203e-15	86.0	COG5373@1|root,COG5373@2|Bacteria,1QXPS@1224|Proteobacteria,1T5Q2@1236|Gammaproteobacteria,1XDDD@135614|Xanthomonadales	135614|Xanthomonadales	S	Type II secretion system protein B	-	-	-	-	-	-	-	-	-	-	-	-	T2SSB
MMD2_k127_5593623_9	1123073.KB899241_gene2322	4.392e-120	406.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1X4ZI@135614|Xanthomonadales	135614|Xanthomonadales	U	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
MMD2_k127_5593623_30	582899.Hden_1976	1.107e-43	164.0	2CD0I@1|root,32RWS@2|Bacteria,1N0MC@1224|Proteobacteria,2U9CM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
MMD2_k127_5593623_2	1500890.JQNL01000001_gene2756	1.086e-274	866.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1X333@135614|Xanthomonadales	135614|Xanthomonadales	I	converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974
MMD2_k127_5593623_6	519989.ECTPHS_06667	1.465e-146	471.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1WX8X@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMD2_k127_5593623_7	414684.RC1_2513	6.617e-126	412.0	COG2204@1|root,COG2204@2|Bacteria,1MWW5@1224|Proteobacteria,2TXAZ@28211|Alphaproteobacteria,2JQAG@204441|Rhodospirillales	204441|Rhodospirillales	K	Sigma-54 interaction domain	-	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
MMD2_k127_5593623_19	1515746.HR45_05995	3.601e-68	239.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,1RS0G@1236|Gammaproteobacteria,2QA1V@267890|Shewanellaceae	1236|Gammaproteobacteria	KT	PFAM PspA IM30 family protein	pspA	GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
MMD2_k127_5593623_35	1121033.AUCF01000003_gene3238	8.412e-16	79.0	2CJWQ@1|root,32C05@2|Bacteria,1Q6G6@1224|Proteobacteria,2VCM2@28211|Alphaproteobacteria,2JUC8@204441|Rhodospirillales	204441|Rhodospirillales	S	Phage shock protein B	-	-	-	ko:K03970	-	-	-	-	ko00000,ko02048	-	-	-	PspB
MMD2_k127_5593623_32	1163408.UU9_14075	7.3e-26	111.0	COG1983@1|root,COG1983@2|Bacteria,1N085@1224|Proteobacteria,1SY31@1236|Gammaproteobacteria,1XBGH@135614|Xanthomonadales	135614|Xanthomonadales	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
MMD2_k127_5593623_39	1331060.RLDS_15090	1.675e-05	50.0	2DNTE@1|root,32Z25@2|Bacteria,1NK1C@1224|Proteobacteria,2UJRY@28211|Alphaproteobacteria,2K7CU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5594398_2	215803.DB30_6069	5.424e-51	209.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YXT4@29|Myxococcales	28221|Deltaproteobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,Pkinase,WD40
MMD2_k127_5594398_1	1500890.JQNL01000001_gene2632	3.163e-51	192.0	COG0515@1|root,COG0515@2|Bacteria,1NJ1M@1224|Proteobacteria,1SZWI@1236|Gammaproteobacteria,1XCXW@135614|Xanthomonadales	135614|Xanthomonadales	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5594398_3	765912.Thimo_2337	1.26e-07	56.0	2EFZ6@1|root,339RC@2|Bacteria,1P76P@1224|Proteobacteria,1SIDJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5594398_0	349124.Hhal_0079	4.462e-130	433.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1X0QS@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
MMD2_k127_5600565_20	861299.J421_1224	4.918e-64	232.0	COG1629@1|root,COG4771@2|Bacteria,1ZUFR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
MMD2_k127_5600565_8	1267533.KB906735_gene4878	1.459e-180	595.0	COG0577@1|root,COG0577@2|Bacteria,3Y6X9@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_5600565_7	234267.Acid_3297	1.511e-215	698.0	COG0577@1|root,COG0577@2|Bacteria,3Y41Z@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_5600565_5	246197.MXAN_1695	6.277e-227	728.0	COG0577@1|root,COG0577@2|Bacteria,1PIKV@1224|Proteobacteria	1224|Proteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_5600565_11	251221.35211983	1.314e-126	436.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_5600565_30	1183438.GKIL_4503	7.13e-22	107.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_5600565_15	768671.ThimaDRAFT_0934	4.362e-112	387.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
MMD2_k127_5600565_24	713586.KB900536_gene2847	2.083e-44	165.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1S6HB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMD2_k127_5600565_4	861299.J421_5876	2.552e-227	733.0	COG0577@1|root,COG0577@2|Bacteria,1ZUI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_5600565_26	627192.SLG_25140	1.301e-39	164.0	2EVK9@1|root,33P0C@2|Bacteria,1NDYB@1224|Proteobacteria,2UQHZ@28211|Alphaproteobacteria,2K9N4@204457|Sphingomonadales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5600565_21	1279017.AQYJ01000027_gene1846	1.44e-61	236.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,464E9@72275|Alteromonadaceae	1236|Gammaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
MMD2_k127_5600565_28	555793.WSK_3236	4.708e-32	129.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5600565_31	555793.WSK_1442	2.08e-18	95.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5600565_19	1123060.JONP01000032_gene1870	3.985e-75	260.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2TSQ4@28211|Alphaproteobacteria,2JV8X@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMD2_k127_5600565_6	1007104.SUS17_2517	8.428e-220	695.0	COG2234@1|root,COG2234@2|Bacteria,1MWQ0@1224|Proteobacteria,2U1HX@28211|Alphaproteobacteria,2JZUX@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMD2_k127_5600565_27	861299.J421_1254	4.251e-36	140.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMD2_k127_5600565_25	1122603.ATVI01000008_gene2177	4.056e-43	167.0	COG1309@1|root,COG1309@2|Bacteria,1MYYA@1224|Proteobacteria,1SZK2@1236|Gammaproteobacteria,1X6U7@135614|Xanthomonadales	135614|Xanthomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMD2_k127_5600565_16	1122604.JONR01000036_gene3795	1.623e-106	359.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,1X38S@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18298,ko:K19586	-	M00641,M00767	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.47,8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
MMD2_k127_5600565_0	1122604.JONR01000036_gene3794	0.0	1442.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X34J@135614|Xanthomonadales	135614|Xanthomonadales	V	Efflux pump membrane transporter	-	-	-	ko:K18299	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.16	-	-	ACR_tran
MMD2_k127_5600565_10	1292034.OR37_02059	3.029e-141	464.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,2KF2T@204458|Caulobacterales	204458|Caulobacterales	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	ko:K18300	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17	-	-	OEP
MMD2_k127_5600565_17	1123354.AUDR01000015_gene273	6.831e-98	330.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,1KRZ5@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Dihydroorotate dehydrogenase	-	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMD2_k127_5600565_1	396588.Tgr7_2295	0.0	1403.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1WX68@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMD2_k127_5600565_3	1340493.JNIF01000003_gene4672	3.968e-244	818.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_5600565_22	1278309.KB907106_gene1341	9.698e-55	197.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XJHS@135619|Oceanospirillales	135619|Oceanospirillales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
MMD2_k127_5600565_9	1121015.N789_02905	2.275e-180	575.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1X3HB@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
MMD2_k127_5600565_12	243233.MCA1458	1.196e-119	393.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1XE38@135618|Methylococcales	135618|Methylococcales	T	PFAM PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
MMD2_k127_5600565_23	1122603.ATVI01000013_gene1327	2.947e-46	171.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1X6SP@135614|Xanthomonadales	135614|Xanthomonadales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
MMD2_k127_5600565_18	1122603.ATVI01000013_gene1326	1.19e-86	298.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1X3M9@135614|Xanthomonadales	135614|Xanthomonadales	P	Transporter	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
MMD2_k127_5600565_13	1304275.C41B8_14520	3.827e-117	394.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
MMD2_k127_5600565_29	2340.JV46_24410	6.183e-25	122.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.89,4.2.2.3	ko:K01224,ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Big_4,Glyco_hydro_53,PKD,SLH
MMD2_k127_5600565_14	1379270.AUXF01000002_gene1479	3.258e-113	378.0	COG1819@1|root,COG1819@2|Bacteria,1ZV4F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_transf_28,UDPGT
MMD2_k127_5600565_2	1121930.AQXG01000001_gene1181	0.0	1077.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
MMD2_k127_5606036_1	1280947.HY30_15865	4.184e-137	455.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43X6D@69657|Hyphomonadaceae	28211|Alphaproteobacteria	CG	alcohol dehydrogenase	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
MMD2_k127_5606036_4	1151118.KB895808_gene2094	8.896e-05	51.0	COG1846@1|root,COG1846@2|Bacteria,2GUJ6@201174|Actinobacteria,1W9ZG@1268|Micrococcaceae	201174|Actinobacteria	K	Iron dependent repressor, N-terminal DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMD2_k127_5606036_2	926566.Terro_0915	4.897e-40	154.0	2CGTC@1|root,331SF@2|Bacteria,3Y7P6@57723|Acidobacteria,2JMRK@204432|Acidobacteriia	204432|Acidobacteriia	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMD2_k127_5606036_0	234267.Acid_6976	4.206e-154	518.0	28JZQ@1|root,2Z9PN@2|Bacteria,3Y4UW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5606036_3	95619.PM1_0218775	2.012e-11	74.0	COG2199@1|root,COG3706@2|Bacteria,1RDWG@1224|Proteobacteria,1S7W2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMD2_k127_5610952_9	1122164.JHWF01000003_gene2083	3.777e-62	225.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,1JDMK@118969|Legionellales	118969|Legionellales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
MMD2_k127_5610952_19	861299.J421_0735	1.208e-33	139.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_0735|-	S	peptidyl-tyrosine sulfation	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	-
MMD2_k127_5610952_17	864051.BurJ1DRAFT_1919	5.945e-38	151.0	COG4922@1|root,COG4922@2|Bacteria,1MYTU@1224|Proteobacteria,2WG68@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5610952_14	266264.Rmet_2592	6.877e-47	178.0	2EIBB@1|root,33C2R@2|Bacteria,1R3EG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5610952_16	1123261.AXDW01000011_gene481	7.562e-43	161.0	2E92A@1|root,333BE@2|Bacteria,1N8BM@1224|Proteobacteria,1SDV1@1236|Gammaproteobacteria,1X8SN@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5610952_3	1123377.AUIV01000001_gene913	1.037e-150	486.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMD2_k127_5610952_22	223926.28808536	1.705e-31	132.0	COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,1S2SV@1236|Gammaproteobacteria,1XT2Q@135623|Vibrionales	135623|Vibrionales	S	(twin-arginine translocation) pathway signal	VPA0371	-	-	-	-	-	-	-	-	-	-	-	Ysc84
MMD2_k127_5610952_7	640081.Dsui_1131	1.223e-84	297.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2VM5U@28216|Betaproteobacteria,2KWUV@206389|Rhodocyclales	206389|Rhodocyclales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
MMD2_k127_5610952_24	278963.ATWD01000001_gene1258	1.545e-10	68.0	2DPXD@1|root,333T1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
MMD2_k127_5610952_0	1232683.ADIMK_0562	2.196e-211	673.0	COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,1RPZ2@1236|Gammaproteobacteria,465G8@72275|Alteromonadaceae	1236|Gammaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6,4.1.1.75	ko:K01652,ko:K12253	ko00290,ko00330,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00330,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R03178,R04672,R04673,R08648	RC00027,RC00106,RC00506,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMD2_k127_5610952_25	1082931.KKY_123	2.35e-10	69.0	2CBAE@1|root,3343U@2|Bacteria,1Q6VU@1224|Proteobacteria,2UJ1K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5610952_23	240015.ACP_3525	1.807e-31	135.0	COG3182@1|root,COG3182@2|Bacteria,3Y2R7@57723|Acidobacteria,2JIBB@204432|Acidobacteriia	204432|Acidobacteriia	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
MMD2_k127_5610952_8	686340.Metal_2948	2.556e-79	283.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XEB2@135618|Methylococcales	135618|Methylococcales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMD2_k127_5610952_5	536019.Mesop_2279	4.035e-124	408.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,2TQQD@28211|Alphaproteobacteria,43JES@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
MMD2_k127_5610952_6	1122603.ATVI01000005_gene3550	1.01e-118	396.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1XCFT@135614|Xanthomonadales	135614|Xanthomonadales	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
MMD2_k127_5610952_15	1122603.ATVI01000005_gene3549	1.726e-43	167.0	COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,1X6TU@135614|Xanthomonadales	135614|Xanthomonadales	D	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
MMD2_k127_5610952_13	1265313.HRUBRA_01305	1.313e-48	191.0	COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1J575@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_16,TPR_8
MMD2_k127_5610952_21	1415780.JPOG01000001_gene3291	9.313e-33	134.0	COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMD2_k127_5610952_12	1122603.ATVI01000005_gene3553	2.601e-49	186.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria,1X7VH@135614|Xanthomonadales	135614|Xanthomonadales	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
MMD2_k127_5610952_20	1122604.JONR01000015_gene138	3.209e-33	140.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S7FH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
MMD2_k127_5610952_11	1122603.ATVI01000005_gene3551	1.039e-54	198.0	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,1X7KH@135614|Xanthomonadales	135614|Xanthomonadales	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
MMD2_k127_5610952_4	1122603.ATVI01000005_gene3550	1.971e-125	419.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1XCFT@135614|Xanthomonadales	135614|Xanthomonadales	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
MMD2_k127_5610952_10	1122604.JONR01000015_gene141	1.015e-60	219.0	COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,1X6TU@135614|Xanthomonadales	135614|Xanthomonadales	D	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
MMD2_k127_5610952_2	1122604.JONR01000013_gene3263	7.372e-155	509.0	COG2223@1|root,COG2223@2|Bacteria,1MXAA@1224|Proteobacteria,1RMZZ@1236|Gammaproteobacteria,1X56Q@135614|Xanthomonadales	135614|Xanthomonadales	P	Major facilitator superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
MMD2_k127_5610952_26	7222.FBpp0156271	1.063e-08	63.0	KOG1037@1|root,KOG1037@2759|Eukaryota,38B7U@33154|Opisthokonta,3BBUM@33208|Metazoa,3CT5Y@33213|Bilateria,41VRJ@6656|Arthropoda,3SG42@50557|Insecta,44XZH@7147|Diptera,45W02@7214|Drosophilidae	33208|Metazoa	KLO	NAD ADP-ribosyltransferase activity. It is involved in the biological process described with protein ADP-ribosylation	PARP1	GO:0000002,GO:0000003,GO:0000122,GO:0000166,GO:0000228,GO:0000302,GO:0000303,GO:0000305,GO:0000715,GO:0000723,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0000791,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001228,GO:0001817,GO:0001818,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002225,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002791,GO:0002792,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003006,GO:0003254,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005703,GO:0005719,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006302,GO:0006310,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006471,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006963,GO:0006974,GO:0006979,GO:0006996,GO:0006997,GO:0007000,GO:0007005,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007552,GO:0007610,GO:0008069,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009303,GO:0009314,GO:0009408,GO:0009410,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009798,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010212,GO:0010243,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010990,GO:0012501,GO:0012505,GO:0014070,GO:0014742,GO:0014743,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016333,GO:0016334,GO:0016485,GO:0016540,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0017144,GO:0018130,GO:0018193,GO:0018209,GO:0018312,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023019,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030225,GO:0030331,GO:0030534,GO:0030575,GO:0030576,GO:0030707,GO:0030808,GO:0030809,GO:0030855,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031960,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032042,GO:0032101,GO:0032103,GO:0032200,GO:0032204,GO:0032205,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032660,GO:0032700,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0033365,GO:0033554,GO:0033683,GO:0033993,GO:0034248,GO:0034250,GO:0034504,GO:0034599,GO:0034605,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0035079,GO:0035080,GO:0035257,GO:0035258,GO:0035363,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042220,GO:0042221,GO:0042391,GO:0042393,GO:0042493,GO:0042592,GO:0042769,GO:0042802,GO:0042826,GO:0042981,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043279,GO:0043388,GO:0043412,GO:0043434,GO:0043484,GO:0043502,GO:0043504,GO:0043523,GO:0043565,GO:0043900,GO:0043902,GO:0043933,GO:0044030,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045087,GO:0045185,GO:0045595,GO:0045597,GO:0045739,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0045980,GO:0046034,GO:0046332,GO:0046483,GO:0047485,GO:0048037,GO:0048148,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050879,GO:0050881,GO:0050882,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051287,GO:0051385,GO:0051427,GO:0051457,GO:0051604,GO:0051606,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051881,GO:0051900,GO:0051901,GO:0055086,GO:0060249,GO:0060255,GO:0060341,GO:0060359,GO:0060390,GO:0060391,GO:0060429,GO:0062012,GO:0062014,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070212,GO:0070412,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0071214,GO:0071241,GO:0071248,GO:0071294,GO:0071310,GO:0071363,GO:0071375,GO:0071417,GO:0071450,GO:0071451,GO:0071478,GO:0071482,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071824,GO:0071840,GO:0072347,GO:0072521,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090092,GO:0090100,GO:0090257,GO:0090304,GO:0090305,GO:0097159,GO:0097305,GO:0097659,GO:0098687,GO:0098781,GO:0104004,GO:0140096,GO:0140097,GO:0140110,GO:1900180,GO:1900182,GO:1900371,GO:1900372,GO:1900407,GO:1900424,GO:1900426,GO:1900542,GO:1900543,GO:1901135,GO:1901214,GO:1901216,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902175,GO:1902531,GO:1902679,GO:1902680,GO:1902882,GO:1903201,GO:1903203,GO:1903376,GO:1903506,GO:1903507,GO:1903508,GO:1903516,GO:1903518,GO:1903530,GO:1903531,GO:1903578,GO:1903579,GO:1903827,GO:1903829,GO:1904044,GO:1904181,GO:1904356,GO:1904357,GO:1904645,GO:1904646,GO:1904760,GO:1904762,GO:1904950,GO:1905076,GO:1905077,GO:1990404,GO:1990837,GO:1990966,GO:2000112,GO:2000113,GO:2000677,GO:2000679,GO:2001020,GO:2001022,GO:2001141,GO:2001169,GO:2001170,GO:2001233,GO:2001242,GO:2001251	2.4.2.30	ko:K10798	ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400	-	-	-	BRCT,PADR1,PARP,PARP_reg,WGR,zf-PARP
MMD2_k127_5610952_1	1382356.JQMP01000001_gene950	1.091e-179	578.0	COG2368@1|root,COG2368@2|Bacteria,2GAH7@200795|Chloroflexi,27XER@189775|Thermomicrobia	189775|Thermomicrobia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
MMD2_k127_5610952_18	247633.GP2143_17796	6.323e-38	158.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5616575_6	1408224.SAMCCGM7_c3418	0.0001697	46.0	COG0508@1|root,COG0508@2|Bacteria,1R0J5@1224|Proteobacteria,2U28K@28211|Alphaproteobacteria,4BATY@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMD2_k127_5616575_5	1192759.AKIB01000088_gene2299	1.407e-05	57.0	COG3946@1|root,COG3946@2|Bacteria,1R7R5@1224|Proteobacteria,2U5U1@28211|Alphaproteobacteria,2K8RW@204457|Sphingomonadales	204457|Sphingomonadales	U	Bacterial virulence protein (VirJ)	-	-	-	-	-	-	-	-	-	-	-	-	VirJ
MMD2_k127_5616575_1	1117647.M5M_17200	1.705e-132	435.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1J4WQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Aspartate tyrosine aromatic aminotransferase	aspC	-	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_5616575_2	243231.GSU2637	2.704e-120	395.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,43TCD@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_5616575_4	130081.XP_005708634.1	3.693e-76	265.0	COG2301@1|root,2QQPK@2759|Eukaryota	2759|Eukaryota	G	regulation of cobalamin metabolic process	CLYBL	GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401	-	ko:K11390	-	-	-	-	ko00000,ko01000	-	-	-	HpcH_HpaI
MMD2_k127_5616575_0	1316936.K678_05101	9.076e-263	837.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,2JPN7@204441|Rhodospirillales	204441|Rhodospirillales	L	ATP-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
MMD2_k127_5616575_3	768671.ThimaDRAFT_1997	7.728e-113	372.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN3T@1236|Gammaproteobacteria,1WXD8@135613|Chromatiales	135613|Chromatiales	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
MMD2_k127_5648_0	864051.BurJ1DRAFT_4700	4.651e-264	827.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2VKQG@28216|Betaproteobacteria,1KIXH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the glutamate synthase family	glt	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
MMD2_k127_5648_11	2002.JOEQ01000021_gene6780	6.942e-20	100.0	COG3393@1|root,COG3393@2|Bacteria,2GN6B@201174|Actinobacteria,4EIYC@85012|Streptosporangiales	201174|Actinobacteria	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
MMD2_k127_5648_8	595537.Varpa_4074	4.961e-39	157.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,4ADKX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0307 family	yjgA	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
MMD2_k127_5648_13	1232437.KL662047_gene5183	0.0004608	48.0	COG2900@1|root,COG2900@2|Bacteria,1QQRC@1224|Proteobacteria,437AB@68525|delta/epsilon subdivisions,2X9YC@28221|Deltaproteobacteria,2MMBN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SlyX	-	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
MMD2_k127_5648_4	926569.ANT_25340	1.795e-73	250.0	COG0652@1|root,COG0652@2|Bacteria,2G69B@200795|Chloroflexi	200795|Chloroflexi	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
MMD2_k127_5648_2	1123073.KB899242_gene1091	1.309e-133	432.0	COG0451@1|root,COG0451@2|Bacteria,1QP8J@1224|Proteobacteria,1RP88@1236|Gammaproteobacteria,1X5KQ@135614|Xanthomonadales	135614|Xanthomonadales	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMD2_k127_5648_3	234267.Acid_4996	2.29e-91	323.0	COG0726@1|root,COG0726@2|Bacteria,3Y51E@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMD2_k127_5648_7	1340493.JNIF01000003_gene4244	1.118e-48	180.0	2ANK7@1|root,31DJB@2|Bacteria,3Y7J7@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
MMD2_k127_5648_6	1165096.ARWF01000001_gene1148	1.607e-56	208.0	COG2193@1|root,COG2193@2|Bacteria,1RF3C@1224|Proteobacteria,2VRIX@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the Dps family	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
MMD2_k127_5648_12	388413.ALPR1_15839	1.33e-15	85.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes,47V7E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5648_5	1121957.ATVL01000001_gene3550	5.697e-69	252.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,47PB1@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_5648_9	1123279.ATUS01000001_gene2643	2.056e-27	118.0	COG3453@1|root,COG3453@2|Bacteria,1QSGD@1224|Proteobacteria,1TKD2@1236|Gammaproteobacteria,1J791@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
MMD2_k127_5648_1	365046.Rta_05370	1.055e-143	460.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,2VHM0@28216|Betaproteobacteria,4ABI5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phenazine biosynthesis protein phzf family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
MMD2_k127_5679222_2	187303.BN69_1463	3.445e-115	381.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,FAD_oxidored,HI0933_like,Lycopene_cycl
MMD2_k127_5679222_13	298654.FraEuI1c_3042	2.242e-33	132.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria	201174|Actinobacteria	K	arsR family	-	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
MMD2_k127_5679222_9	288000.BBta_5247	5.227e-58	214.0	COG0625@1|root,COG0625@2|Bacteria,1RC4Y@1224|Proteobacteria,2U6JK@28211|Alphaproteobacteria,3JVU5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
MMD2_k127_5679222_11	1320556.AVBP01000007_gene621	6.798e-54	197.0	COG3832@1|root,COG3832@2|Bacteria,1RAW4@1224|Proteobacteria,2UI5Z@28211|Alphaproteobacteria,43P5K@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMD2_k127_5679222_15	629773.AORY01000005_gene2660	8.196e-26	121.0	COG2207@1|root,COG2207@2|Bacteria,1MXT9@1224|Proteobacteria,2U0UP@28211|Alphaproteobacteria,2K7AB@204457|Sphingomonadales	204457|Sphingomonadales	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
MMD2_k127_5679222_8	1254432.SCE1572_19530	2.199e-60	215.0	COG4122@1|root,COG4122@2|Bacteria,1N57D@1224|Proteobacteria,437H4@68525|delta/epsilon subdivisions,2WYJM@28221|Deltaproteobacteria,2Z0SM@29|Myxococcales	28221|Deltaproteobacteria	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
MMD2_k127_5679222_17	1046714.AMRX01000008_gene895	6.217e-10	67.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,464EV@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
MMD2_k127_5679222_12	1122201.AUAZ01000001_gene2229	6.955e-38	146.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,464EV@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
MMD2_k127_5679222_4	366602.Caul_1136	6.919e-82	302.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3JH@28211|Alphaproteobacteria,2KK80@204458|Caulobacterales	204458|Caulobacterales	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_5679222_3	357808.RoseRS_0328	2.064e-89	305.0	COG1893@1|root,COG1893@2|Bacteria,2G9PB@200795|Chloroflexi,3772C@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMD2_k127_5679222_1	113395.AXAI01000016_gene4943	6.783e-138	455.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3JS0R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	repeat protein	MA20_04930	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5679222_0	883080.HMPREF9697_01453	1.901e-153	494.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,3JQU4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD2_k127_5679222_16	1296416.JACB01000070_gene72	3.487e-10	72.0	2EQFK@1|root,33I1K@2|Bacteria,4P4HB@976|Bacteroidetes,1I9J6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5679222_6	639030.JHVA01000001_gene2808	1.191e-69	256.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria,2JM9F@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_5679222_10	1337936.IJ00_09305	4.45e-55	196.0	COG0454@1|root,COG0454@2|Bacteria,1G5EA@1117|Cyanobacteria,1HSMP@1161|Nostocales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
MMD2_k127_5679222_7	981369.JQMJ01000004_gene293	8.507e-63	225.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,2NHK8@228398|Streptacidiphilus	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
MMD2_k127_5679222_5	1133849.O3I_017225	2.073e-71	247.0	COG0451@1|root,COG0451@2|Bacteria,2IIE9@201174|Actinobacteria,4G8XR@85025|Nocardiaceae	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
MMD2_k127_5679222_14	522306.CAP2UW1_1692	1.027e-26	111.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2W9C4@28216|Betaproteobacteria,1KQ5B@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
MMD2_k127_5703584_18	883078.HMPREF9695_04926	1.748e-26	113.0	2DQCB@1|root,335WZ@2|Bacteria,1N06Y@1224|Proteobacteria,2UCE4@28211|Alphaproteobacteria,3K020@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Family of unknown function (DUF5335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5335
MMD2_k127_5703584_4	266117.Rxyl_0206	1.023e-149	487.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4CR1A@84995|Rubrobacteria	84995|Rubrobacteria	F	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD2_k127_5703584_22	1120983.KB894577_gene3669	9.236e-15	88.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,2TUVZ@28211|Alphaproteobacteria,1JQH6@119043|Rhodobiaceae	28211|Alphaproteobacteria	Q	Isochorismatase family	rutB	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
MMD2_k127_5703584_11	935567.JAES01000007_gene1860	1.18e-61	235.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria,1XDC3@135614|Xanthomonadales	135614|Xanthomonadales	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5703584_12	338969.Rfer_0087	7.463e-46	173.0	COG0526@1|root,COG0526@2|Bacteria,1RAW3@1224|Proteobacteria,2VP3Z@28216|Betaproteobacteria,4AEFP@80864|Comamonadaceae	28216|Betaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
MMD2_k127_5703584_5	456442.Mboo_0427	2.019e-114	383.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N95K@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMD2_k127_5703584_9	456442.Mboo_0426	3.595e-74	258.0	COG0842@1|root,arCOG01467@2157|Archaea,2XU41@28890|Euryarchaeota,2N9R3@224756|Methanomicrobia	224756|Methanomicrobia	V	TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMD2_k127_5703584_2	926549.KI421517_gene1092	5.212e-168	552.0	COG3420@1|root,COG3420@2|Bacteria,4P1XP@976|Bacteroidetes,47UIA@768503|Cytophagia	976|Bacteroidetes	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5703584_23	44454.NF84_09475	1.692e-12	80.0	COG3340@1|root,COG3340@2|Bacteria,2IC7Y@201174|Actinobacteria,234WT@1762|Mycobacteriaceae	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
MMD2_k127_5703584_14	378806.STAUR_0538	9.976e-43	173.0	COG1541@1|root,COG1541@2|Bacteria,1NRF7@1224|Proteobacteria,438AI@68525|delta/epsilon subdivisions,2X3JY@28221|Deltaproteobacteria,2YWCX@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
MMD2_k127_5703584_8	667632.KB890169_gene5038	1.055e-83	295.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,1K09J@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Cysteine desulfurase	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
MMD2_k127_5703584_7	1254432.SCE1572_14460	1.822e-91	310.0	COG1720@1|root,COG2026@1|root,COG1720@2|Bacteria,COG2026@2|Bacteria,1MUF0@1224|Proteobacteria,42T7R@68525|delta/epsilon subdivisions,2WNQ2@28221|Deltaproteobacteria,2Z1S5@29|Myxococcales	28221|Deltaproteobacteria	DJ	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
MMD2_k127_5703584_3	1234364.AMSF01000048_gene2039	2.14e-150	505.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X2Z4@135614|Xanthomonadales	135614|Xanthomonadales	T	phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
MMD2_k127_5703584_13	397945.Aave_4293	2.258e-44	169.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,2VSJJ@28216|Betaproteobacteria,4AEGW@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5703584_10	1336233.JAEH01000018_gene3100	8.227e-62	236.0	2C8CD@1|root,2Z9AD@2|Bacteria,1N17D@1224|Proteobacteria,1RRIP@1236|Gammaproteobacteria,2QAV5@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5703584_21	925409.KI911562_gene682	4.711e-19	94.0	COG2940@1|root,COG2940@2|Bacteria	2|Bacteria	K	SET domain	-	-	-	-	-	-	-	-	-	-	-	-	Ank,SET
MMD2_k127_5703584_0	1210884.HG799462_gene8667	0.0	1377.0	COG0110@1|root,COG1020@1|root,COG0110@2|Bacteria,COG1020@2|Bacteria,2IZDX@203682|Planctomycetes	203682|Planctomycetes	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
MMD2_k127_5703584_17	246197.MXAN_5220	1.355e-33	139.0	COG0122@1|root,COG5483@1|root,COG0122@2|Bacteria,COG5483@2|Bacteria,1PERA@1224|Proteobacteria,435TA@68525|delta/epsilon subdivisions,2X08G@28221|Deltaproteobacteria,2Z18M@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMD2_k127_5703584_19	246197.MXAN_5220	1.001e-22	108.0	COG0122@1|root,COG5483@1|root,COG0122@2|Bacteria,COG5483@2|Bacteria,1PERA@1224|Proteobacteria,435TA@68525|delta/epsilon subdivisions,2X08G@28221|Deltaproteobacteria,2Z18M@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMD2_k127_5703584_15	1123368.AUIS01000035_gene82	5.376e-42	159.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,1S9PQ@1236|Gammaproteobacteria,2ND29@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
MMD2_k127_5703584_25	716928.AJQT01000094_gene4420	0.0001591	47.0	28VY6@1|root,2ZHZE@2|Bacteria,1P9ZV@1224|Proteobacteria,2VE8T@28211|Alphaproteobacteria,4BHGG@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5703584_1	1122164.JHWF01000031_gene2289	0.0	1096.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,1JCFA@118969|Legionellales	118969|Legionellales	P	Cytochrome C and Quinol oxidase polypeptide I	norB	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
MMD2_k127_5703584_16	555793.WSK_3235	5.43e-35	146.0	2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5703584_24	589873.EP13_13630	7.713e-08	60.0	2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5703584_6	748247.AZKH_0594	8.238e-100	342.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,2KWP5@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMD2_k127_5741011_42	247633.GP2143_17796	2.401e-37	145.0	28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5741011_58	649349.Lbys_1338	2.997e-07	55.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,47RIT@768503|Cytophagia	976|Bacteroidetes	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
MMD2_k127_5741011_2	2340.JV46_03050	1.936e-220	706.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1J4SW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
MMD2_k127_5741011_29	406818.XBJ1_0328	3.545e-68	241.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
MMD2_k127_5741011_39	1123517.JOMR01000001_gene1118	7.353e-45	167.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,460SS@72273|Thiotrichales	72273|Thiotrichales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
MMD2_k127_5741011_45	1397528.Q671_03635	1.52e-36	139.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,1XKJ3@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
MMD2_k127_5741011_59	713586.KB900536_gene2975	1.55e-05	56.0	2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1RY97@1236|Gammaproteobacteria,1WXMV@135613|Chromatiales	135613|Chromatiales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
MMD2_k127_5741011_33	1255043.TVNIR_3257	5.815e-54	193.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1WYD2@135613|Chromatiales	135613|Chromatiales	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
MMD2_k127_5741011_4	1123401.JHYQ01000021_gene1067	1.45e-177	567.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales	72273|Thiotrichales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
MMD2_k127_5741011_30	1000565.METUNv1_02453	1.359e-65	232.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMD2_k127_5741011_20	1122604.JONR01000001_gene1978	1.316e-83	288.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1RQUV@1236|Gammaproteobacteria,1X4AA@135614|Xanthomonadales	135614|Xanthomonadales	T	phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
MMD2_k127_5741011_17	1000565.METUNv1_02451	4.487e-101	356.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
MMD2_k127_5741011_6	1122603.ATVI01000005_gene3329	3.203e-170	547.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1X3DQ@135614|Xanthomonadales	135614|Xanthomonadales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
MMD2_k127_5741011_12	314278.NB231_05030	8.877e-137	448.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1WWQM@135613|Chromatiales	135613|Chromatiales	P	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
MMD2_k127_5741011_10	1122207.MUS1_03610	2.095e-146	477.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1XIPR@135619|Oceanospirillales	135619|Oceanospirillales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
MMD2_k127_5741011_48	2340.JV46_04240	2.358e-31	126.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,1J6MP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
MMD2_k127_5741011_37	686340.Metal_0946	3.008e-50	186.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1XFCM@135618|Methylococcales	135618|Methylococcales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
MMD2_k127_5741011_18	701347.Entcl_1115	1e-90	304.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,3X1ZR@547|Enterobacter	1236|Gammaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
MMD2_k127_5741011_36	857087.Metme_3964	8.936e-52	185.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1XFFD@135618|Methylococcales	135618|Methylococcales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
MMD2_k127_5741011_28	580332.Slit_0818	1.505e-72	255.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,2VWPY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
MMD2_k127_5741011_22	1265505.ATUG01000001_gene4659	1.06e-80	287.0	COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria,2MJCH@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
MMD2_k127_5741011_50	1121918.ARWE01000001_gene965	2.465e-29	123.0	COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,42TZJ@68525|delta/epsilon subdivisions,2WQB8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Tripartite ATP-independent periplasmic transporter, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
MMD2_k127_5741011_9	1298593.TOL_3421	2.652e-153	497.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XIS2@135619|Oceanospirillales	135619|Oceanospirillales	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
MMD2_k127_5741011_11	1121374.KB891586_gene2496	1.139e-143	477.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OU	Signal peptide peptidase	sppA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
MMD2_k127_5741011_53	519989.ECTPHS_00265	3.837e-25	109.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1WYI6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the HSP15 family	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
MMD2_k127_5741011_47	1232410.KI421421_gene3305	3.12e-34	144.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,42TJ0@68525|delta/epsilon subdivisions,2WSKD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
MMD2_k127_5741011_25	380358.XALC_0475	3.762e-76	259.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales	135614|Xanthomonadales	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
MMD2_k127_5741011_38	1283300.ATXB01000001_gene922	9.766e-49	178.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1XF3J@135618|Methylococcales	135618|Methylococcales	C	TIGRFAM SUF system FeS	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMD2_k127_5741011_7	1348657.M622_02535	1.252e-163	531.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,2KUXB@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
MMD2_k127_5741011_21	1255043.TVNIR_1840	5.482e-83	291.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,1WWK5@135613|Chromatiales	135613|Chromatiales	O	FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
MMD2_k127_5741011_14	948106.AWZT01000053_gene1578	1.02e-110	362.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2VNGT@28216|Betaproteobacteria,1K5H7@119060|Burkholderiaceae	28216|Betaproteobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMD2_k127_5741011_1	472759.Nhal_0688	4.038e-271	840.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1WWT1@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
MMD2_k127_5741011_44	1163408.UU9_16301	1.436e-36	143.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X6CG@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMD2_k127_5741011_19	1304275.C41B8_15932	9.326e-88	308.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	bepA	GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
MMD2_k127_5741011_32	243233.MCA0664	4.661e-55	196.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XF8T@135618|Methylococcales	135618|Methylococcales	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMD2_k127_5741011_35	349124.Hhal_2199	1.692e-53	193.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1WWJB@135613|Chromatiales	135613|Chromatiales	E	PFAM Amino acid-binding ACT	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
MMD2_k127_5741011_16	396588.Tgr7_0827	1.225e-101	338.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1WWMV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMD2_k127_5741011_13	1121033.AUCF01000001_gene2160	1.032e-131	434.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TS80@28211|Alphaproteobacteria,2JR07@204441|Rhodospirillales	204441|Rhodospirillales	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
MMD2_k127_5741011_23	880072.Desac_0027	5.642e-79	281.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMD2_k127_5741011_15	1341181.FLJC2902T_31040	5.652e-108	361.0	COG0702@1|root,COG0702@2|Bacteria,4NICI@976|Bacteroidetes,1IIU7@117743|Flavobacteriia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
MMD2_k127_5741011_57	1197906.CAJQ02000027_gene1525	1.835e-09	61.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
MMD2_k127_5741011_8	396588.Tgr7_1073	2.147e-157	512.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1WX0K@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
MMD2_k127_5741011_46	1532557.JL37_11530	2.463e-36	141.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,3T46T@506|Alcaligenaceae	28216|Betaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
MMD2_k127_5741011_26	247633.GP2143_07229	1.322e-75	258.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1J58W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
MMD2_k127_5741011_43	1121346.KB899816_gene3353	3.059e-37	144.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,26Y4P@186822|Paenibacillaceae	91061|Bacilli	FG	HIT family	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
MMD2_k127_5741011_27	1122951.ATUE01000005_gene1744	6.759e-75	262.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,3NIIC@468|Moraxellaceae	1236|Gammaproteobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
MMD2_k127_5741011_41	765912.Thimo_3491	1.214e-38	153.0	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1WY3A@135613|Chromatiales	135613|Chromatiales	T	SH3 domain	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
MMD2_k127_5741011_52	1304275.C41B8_12170	2.627e-25	111.0	COG3151@1|root,COG3151@2|Bacteria,1NAPI@1224|Proteobacteria,1SEY8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1249)	-	-	-	ko:K09920	-	-	-	-	ko00000	-	-	-	DUF1249
MMD2_k127_5741011_5	880073.Calab_0516	4.793e-171	561.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,PDZ_2,Peptidase_S41
MMD2_k127_5741011_55	378806.STAUR_3351	5.899e-13	82.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	FHA,Yop-YscD_cpl
MMD2_k127_5741011_34	1279017.AQYJ01000022_gene2606	1.228e-53	197.0	29B18@1|root,2ZY02@2|Bacteria,1REMG@1224|Proteobacteria,1S4B1@1236|Gammaproteobacteria,46AUF@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5741011_49	1279017.AQYJ01000022_gene2607	5.415e-30	128.0	2C5F4@1|root,31I7F@2|Bacteria,1RHUH@1224|Proteobacteria,1S7M2@1236|Gammaproteobacteria,46BAF@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5741011_51	1282360.ABAC460_18665	2.029e-27	120.0	COG4625@1|root,COG4625@2|Bacteria,1N0QY@1224|Proteobacteria,2UFXU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5741011_54	1123257.AUFV01000015_gene3589	2.271e-24	111.0	COG2353@1|root,COG2353@2|Bacteria,1N3P9@1224|Proteobacteria,1SDBE@1236|Gammaproteobacteria,1XAHR@135614|Xanthomonadales	135614|Xanthomonadales	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
MMD2_k127_5741011_24	1382356.JQMP01000003_gene2316	2.48e-76	279.0	COG1680@1|root,COG1680@2|Bacteria,2G6IE@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMD2_k127_5741011_56	1112274.KI911560_gene1492	1.521e-12	71.0	COG2879@1|root,COG2879@2|Bacteria,1NQ41@1224|Proteobacteria,2WFEQ@28216|Betaproteobacteria,2KN8N@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Selenoprotein, putative	-	-	-	-	-	-	-	-	-	-	-	-	Sel_put
MMD2_k127_5741011_0	1123368.AUIS01000004_gene116	0.0	1094.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,1RMG4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Carbon starvation protein	cstA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
MMD2_k127_5741011_3	1123504.JQKD01000024_gene294	1.65e-208	660.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,4AA9X@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
MMD2_k127_5741011_40	1121937.AUHJ01000010_gene1633	5.815e-42	171.0	COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria,46DCA@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8,Transglut_core
MMD2_k127_5932054_26	381666.H16_A0623	2.599e-17	83.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2VIK2@28216|Betaproteobacteria,1K4R8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMD2_k127_5932054_21	1415754.JQMK01000002_gene2476	3.951e-34	138.0	2F9VU@1|root,3425C@2|Bacteria,1NXNW@1224|Proteobacteria,1SPVX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
MMD2_k127_5932054_29	316067.Geob_0079	4.01e-11	68.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD2_k127_5932054_8	378806.STAUR_6676	1.321e-143	460.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YXF2@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
MMD2_k127_5932054_13	349163.Acry_1425	7.921e-93	320.0	COG1028@1|root,COG1028@2|Bacteria,1MWJQ@1224|Proteobacteria,2TSQ1@28211|Alphaproteobacteria,2JRQ3@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD2_k127_5932054_19	1207063.P24_11400	1.008e-50	190.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2TUR9@28211|Alphaproteobacteria,2JSEA@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD2_k127_5932054_30	1517416.IDAT_02300	6.308e-06	52.0	2ETTY@1|root,33MBB@2|Bacteria,1NHWU@1224|Proteobacteria,1SW84@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5932054_32	1000565.METUNv1_01134	0.0008	48.0	2EGUY@1|root,33AM4@2|Bacteria,1NGGE@1224|Proteobacteria,2VY4M@28216|Betaproteobacteria,2KXIC@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5932054_27	1209072.ALBT01000033_gene1619	1.041e-13	78.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,1FH9W@10|Cellvibrio	1236|Gammaproteobacteria	S	Glycine zipper 2TM domain	ycfJ	GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
MMD2_k127_5932054_31	1122194.AUHU01000005_gene813	0.0007884	49.0	2E5T6@1|root,330HH@2|Bacteria,1N7RC@1224|Proteobacteria,1SE9V@1236|Gammaproteobacteria,468A0@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5932054_28	870187.Thini_3951	3.232e-12	69.0	COG5487@1|root,COG5487@2|Bacteria,1NCF3@1224|Proteobacteria,1SCWG@1236|Gammaproteobacteria,461H8@72273|Thiotrichales	72273|Thiotrichales	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
MMD2_k127_5932054_23	1123054.KB907723_gene2840	5.134e-33	137.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Periplasmic or secreted lipoprotein	osmY	GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
MMD2_k127_5932054_9	349521.HCH_04929	3.856e-131	432.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRR1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD2_k127_5932054_22	269799.Gmet_2811	3.339e-33	148.0	COG2770@1|root,COG4251@1|root,COG2770@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42QPS@68525|delta/epsilon subdivisions,2WMWT@28221|Deltaproteobacteria,43T94@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase, Cache_1, HAMP and PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,dCache_1
MMD2_k127_5932054_12	575540.Isop_0300	1.467e-98	341.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
MMD2_k127_5932054_20	1173024.KI912151_gene2025	2.856e-43	162.0	COG1764@1|root,COG1764@2|Bacteria,1G767@1117|Cyanobacteria	1117|Cyanobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
MMD2_k127_5932054_0	666509.RCA23_c08390	8.315e-253	784.0	COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	2.1.1.341	ko:K15066	ko00627,ko01120,map00627,map01120	-	R09271,R10136	RC00113,RC00392	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
MMD2_k127_5932054_10	1502852.FG94_02327	8.986e-131	432.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2VH58@28216|Betaproteobacteria,472E9@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_5932054_15	626418.bglu_1g30320	9.314e-59	214.0	COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,2VQDM@28216|Betaproteobacteria,1K24W@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_5932054_6	1122603.ATVI01000006_gene327	1.759e-196	623.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,1X30H@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
MMD2_k127_5932054_5	266117.Rxyl_1565	5.194e-198	627.0	COG0404@1|root,COG0404@2|Bacteria,2GPU4@201174|Actinobacteria,4CRTT@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM glycine cleavage T protein (aminomethyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
MMD2_k127_5932054_1	935840.JAEQ01000003_gene279	2.508e-223	701.0	COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminomethyltransferase folate-binding domain	-	-	2.1.1.341	ko:K15066	ko00627,ko01120,map00627,map01120	-	R09271,R10136	RC00113,RC00392	ko00000,ko00001,ko01000	-	-	-	GCV_T,GCV_T_C
MMD2_k127_5932054_2	1356854.N007_02090	6.461e-217	688.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli	91061|Bacilli	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
MMD2_k127_5932054_3	234267.Acid_2557	9.098e-216	693.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
MMD2_k127_5932054_18	1300345.LF41_589	1.104e-54	210.0	2EVET@1|root,33NV8@2|Bacteria,1NMPW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5932054_4	1340493.JNIF01000003_gene4672	4.475e-206	681.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMD2_k127_5932054_24	234267.Acid_3123	4.384e-27	121.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_5932054_7	1267535.KB906767_gene3664	8.662e-156	520.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
MMD2_k127_5932054_16	743719.PaelaDRAFT_4208	1.661e-58	217.0	COG1960@1|root,COG1960@2|Bacteria,1UXYJ@1239|Firmicutes,4HD52@91061|Bacilli,26S4I@186822|Paenibacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2
MMD2_k127_5932054_17	502025.Hoch_5491	6.974e-56	206.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,437RC@68525|delta/epsilon subdivisions,2X304@28221|Deltaproteobacteria,2YTVQ@29|Myxococcales	28221|Deltaproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PCMT
MMD2_k127_5932054_14	3885.XP_007161375.1	3.371e-88	302.0	COG0115@1|root,KOG0975@2759|Eukaryota,37N35@33090|Viridiplantae,3G9PH@35493|Streptophyta,4JJUG@91835|fabids	35493|Streptophyta	E	Branched-chain-amino-acid aminotransferase-like protein 3	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008153,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046482,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.3.38	ko:K18482	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
MMD2_k127_5932054_11	76114.ebA6730	4.364e-126	413.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2W0ZB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5932054_25	1384056.N787_06630	2.253e-26	109.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,1T613@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
MMD2_k127_5932158_1	105559.Nwat_2894	1.01e-196	644.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg
MMD2_k127_5932158_8	1125863.JAFN01000001_gene1654	3.589e-87	329.0	2A6A4@1|root,30V2R@2|Bacteria,1RENE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
MMD2_k127_5932158_12	1424334.W822_03610	2.132e-62	218.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2WF7W@28216|Betaproteobacteria,3T4A4@506|Alcaligenaceae	28216|Betaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMD2_k127_5932158_10	1122135.KB893134_gene3890	3.111e-70	248.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
MMD2_k127_5932158_6	55529.EKX46932	3.199e-106	362.0	KOG1406@1|root,KOG1406@2759|Eukaryota	2759|Eukaryota	I	propanoyl-CoA C-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
MMD2_k127_5932158_20	1121935.AQXX01000005_gene681	1.423e-32	131.0	2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5932158_7	1122611.KB903940_gene1706	7.765e-92	305.0	28N0F@1|root,2ZB6V@2|Bacteria,2I31F@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_5932158_13	314278.NB231_15073	1.12e-58	213.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	yfhC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD2_k127_5932158_5	59538.XP_005970471.1	1.001e-122	406.0	COG0579@1|root,KOG2665@2759|Eukaryota,397NY@33154|Opisthokonta,3BCE7@33208|Metazoa,3CXG5@33213|Bilateria,48AID@7711|Chordata,490X2@7742|Vertebrata,3JCWX@40674|Mammalia,4J11X@91561|Cetartiodactyla	33208|Metazoa	S	L-2-hydroxyglutarate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMD2_k127_5932158_11	1124780.ANNU01000078_gene755	3.403e-68	248.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
MMD2_k127_5932158_19	1532558.JL39_05985	3.376e-34	144.0	COG3963@1|root,COG3963@2|Bacteria,1R904@1224|Proteobacteria,2VGE8@28211|Alphaproteobacteria,4BNJ3@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
MMD2_k127_5932158_14	1095769.CAHF01000021_gene943	7.38e-53	194.0	COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2VVC1@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
MMD2_k127_5932158_16	396588.Tgr7_3233	2.898e-39	152.0	COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,1SAXA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	belongs to the Fur family	-	-	-	ko:K09826	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMD2_k127_5932158_24	153948.NAL212_2900	2.695e-17	89.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,2VVPQ@28216|Betaproteobacteria,37394@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Type II transport protein GspH	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
MMD2_k127_5932158_26	1226994.AMZB01000138_gene5749	3.643e-09	66.0	COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,1SGGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG4970 Tfp pilus assembly protein FimT	fimT	-	-	ko:K08084,ko:K08085	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
MMD2_k127_5932158_25	1283300.ATXB01000001_gene79	3.652e-16	88.0	COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,1XFI4@135618|Methylococcales	135618|Methylococcales	NU	TIGRFAM Pilus modification type IV, PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
MMD2_k127_5932158_22	1415779.JOMH01000001_gene2672	2.325e-20	104.0	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1X8AT@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type IV Pilus-assembly protein W	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
MMD2_k127_5932158_27	443152.MDG893_12914	0.0001184	53.0	COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria,1SGXT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
MMD2_k127_5932158_2	351348.Maqu_0871	2.525e-189	635.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
MMD2_k127_5932158_23	95619.PM1_0205645	9.234e-18	88.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG4968 Tfp pilus assembly protein PilE	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
MMD2_k127_5932158_15	1232683.ADIMK_0976	2.343e-42	171.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,467DX@72275|Alteromonadaceae	1236|Gammaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
MMD2_k127_5932158_0	1469245.JFBG01000019_gene1125	0.0	1466.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales	135613|Chromatiales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
MMD2_k127_5932158_9	159087.Daro_3047	1.437e-74	274.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,2KVAZ@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
MMD2_k127_5932158_3	1046724.KB889919_gene201	2.618e-168	545.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,4663F@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	iECO103_1326.ECO103_1114	MVIN
MMD2_k127_5932158_21	1121923.GPUN_0281	1.124e-20	94.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,467QN@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
MMD2_k127_5932158_4	396588.Tgr7_3208	1.258e-133	435.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1WX4T@135613|Chromatiales	135613|Chromatiales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
MMD2_k127_5932158_18	740709.A10D4_03070	2.158e-34	135.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,2QGB8@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
MMD2_k127_5932158_17	754477.Q7C_2169	1.481e-35	137.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,460ZR@72273|Thiotrichales	72273|Thiotrichales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
MMD2_k127_5944004_2	395493.BegalDRAFT_0930	4.617e-114	378.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
MMD2_k127_5944004_4	1158182.KB905021_gene708	2.139e-33	138.0	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria,1WYYF@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1244)	-	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
MMD2_k127_5944004_3	43989.cce_4269	6.316e-105	357.0	KOG1584@1|root,31CAG@2|Bacteria,1G8T0@1117|Cyanobacteria,3KFWM@43988|Cyanothece	1117|Cyanobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
MMD2_k127_5944004_5	1122222.AXWR01000009_gene714	4.809e-29	122.0	2CBAE@1|root,32YK1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5944004_0	452637.Oter_3042	2.258e-270	846.0	COG0405@1|root,COG0405@2|Bacteria,46SGY@74201|Verrucomicrobia,3K9NS@414999|Opitutae	414999|Opitutae	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMD2_k127_5944004_1	1123229.AUBC01000029_gene3538	4.898e-125	440.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2TQVF@28211|Alphaproteobacteria,3JSFI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	AAA C-terminal domain	rarA	GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
MMD2_k127_5944004_7	360910.BAV2137	1.615e-10	65.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,3T295@506|Alcaligenaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMD2_k127_5976599_1	572477.Alvin_2064	5.238e-223	709.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales	135613|Chromatiales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
MMD2_k127_5976599_7	338963.Pcar_1475	2.661e-50	191.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,42SMK@68525|delta/epsilon subdivisions,2WSC2@28221|Deltaproteobacteria,43TI9@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMD2_k127_5976599_9	247634.GPB2148_1594	1.693e-29	122.0	2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_5976599_0	112098.XP_008606431.1	3.209e-228	749.0	COG0265@1|root,KOG1421@2759|Eukaryota	2759|Eukaryota	O	serine-type endopeptidase activity	NMA111	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006508,GO:0006629,GO:0006807,GO:0006915,GO:0006950,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009642,GO:0009644,GO:0009892,GO:0009987,GO:0010109,GO:0010205,GO:0012501,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0033554,GO:0034605,GO:0042548,GO:0043155,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043467,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051603,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1905156	-	-	-	-	-	-	-	-	-	-	PDZ,PDZ_1,PDZ_2,Trypsin_2
MMD2_k127_5976599_4	768671.ThimaDRAFT_1410	3.309e-83	306.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1WVWX@135613|Chromatiales	135613|Chromatiales	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R08768	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
MMD2_k127_5976599_3	314278.NB231_13206	3.156e-94	339.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales	135613|Chromatiales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
MMD2_k127_5976599_2	396588.Tgr7_2764	1.769e-178	571.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales	135613|Chromatiales	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
MMD2_k127_5976599_11	1123368.AUIS01000005_gene378	5.439e-18	92.0	COG3079@1|root,COG3079@2|Bacteria	2|Bacteria	S	Belongs to the UPF0149 family	ygfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09895	-	-	-	-	ko00000	-	-	-	UPF0149
MMD2_k127_5976599_10	713586.KB900536_gene2593	3.174e-23	106.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1WZF3@135613|Chromatiales	135613|Chromatiales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
MMD2_k127_5976599_8	1469245.JFBG01000015_gene1013	3.944e-38	151.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1WYDB@135613|Chromatiales	135613|Chromatiales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
MMD2_k127_5976599_6	1121918.ARWE01000001_gene12	2.021e-65	231.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,43UP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
MMD2_k127_5976599_5	1129794.C427_0936	6.215e-81	277.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,46422@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
MMD2_k127_6003959_28	1323663.AROI01000051_gene4001	1.116e-22	102.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	rhodanese-related sulfurtransferase	yibN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
MMD2_k127_6003959_27	314265.R2601_14890	5.437e-29	117.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
MMD2_k127_6003959_26	472759.Nhal_0026	9.289e-38	152.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1WY33@135613|Chromatiales	135613|Chromatiales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
MMD2_k127_6003959_13	1304275.C41B8_14450	4.532e-104	352.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iJN746.PP_4169,iSFV_1184.SFV_3923	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
MMD2_k127_6003959_23	767434.Fraau_3109	6.464e-62	223.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1X643@135614|Xanthomonadales	135614|Xanthomonadales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
MMD2_k127_6003959_8	472759.Nhal_3461	5.789e-153	488.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1WW5T@135613|Chromatiales	135613|Chromatiales	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMD2_k127_6003959_21	1184267.A11Q_918	3.443e-69	256.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2MT1S@213481|Bdellovibrionales,2WJVP@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
MMD2_k127_6003959_16	338963.Pcar_1256	5.67e-88	312.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
MMD2_k127_6003959_6	572477.Alvin_2997	3.217e-173	560.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WW4B@135613|Chromatiales	135613|Chromatiales	T	response regulator	glnG	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD2_k127_6003959_15	1122604.JONR01000009_gene2415	3.032e-97	338.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1X3AZ@135614|Xanthomonadales	135614|Xanthomonadales	T	Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
MMD2_k127_6003959_31	398579.Spea_3928	6.868e-19	93.0	2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,2QBX8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,DUF4124
MMD2_k127_6003959_2	243233.MCA1677	1.635e-247	769.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1XEEH@135618|Methylococcales	135618|Methylococcales	F	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
MMD2_k127_6003959_3	575540.Isop_3259	1.092e-204	649.0	COG0423@1|root,COG0423@2|Bacteria,2IY4R@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
MMD2_k127_6003959_24	637389.Acaty_c2233	3.306e-56	201.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,2NBS8@225057|Acidithiobacillales	225057|Acidithiobacillales	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
MMD2_k127_6003959_20	105559.Nwat_2728	4.904e-71	251.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1WXP3@135613|Chromatiales	135613|Chromatiales	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMD2_k127_6003959_0	713586.KB900536_gene2143	0.0	1116.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMD2_k127_6003959_22	935567.JAES01000008_gene1936	2.348e-65	237.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1X3R9@135614|Xanthomonadales	135614|Xanthomonadales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
MMD2_k127_6003959_11	1121013.P873_06110	1.1e-124	409.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1X3F0@135614|Xanthomonadales	135614|Xanthomonadales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
MMD2_k127_6003959_5	187272.Mlg_0001	1.633e-186	604.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales	135613|Chromatiales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
MMD2_k127_6003959_32	713586.KB900536_gene2139	1.105e-15	79.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
MMD2_k127_6003959_30	1278971.AOGF01000004_gene1221	4.335e-20	96.0	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1Y8T1@135625|Pasteurellales	135625|Pasteurellales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
MMD2_k127_6003959_9	472759.Nhal_3959	4.707e-135	450.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales	135613|Chromatiales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
MMD2_k127_6003959_10	1121013.P873_06135	9.403e-129	425.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1X3DW@135614|Xanthomonadales	135614|Xanthomonadales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
MMD2_k127_6003959_29	573370.DMR_44430	1.743e-22	106.0	COG2199@1|root,COG3706@2|Bacteria,1MVCZ@1224|Proteobacteria,42S7D@68525|delta/epsilon subdivisions,2WNIU@28221|Deltaproteobacteria,2M9Q2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
MMD2_k127_6003959_18	1121013.P873_06145	7.233e-76	273.0	COG1668@1|root,COG1668@2|Bacteria,1NK4G@1224|Proteobacteria,1RMMK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CP	COG1668 ABC-type Na efflux pump, permease component	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3
MMD2_k127_6003959_17	1234364.AMSF01000061_gene2120	3.326e-80	278.0	COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,1RY2V@1236|Gammaproteobacteria,1X307@135614|Xanthomonadales	135614|Xanthomonadales	CP	abc transporter atp-binding protein	-	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
MMD2_k127_6003959_14	1056820.KB900631_gene2323	3.557e-101	347.0	COG0400@1|root,COG0596@1|root,COG0400@2|Bacteria,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,2PND2@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
MMD2_k127_6003959_1	519989.ECTPHS_08773	1.146e-270	861.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1WXBH@135613|Chromatiales	135613|Chromatiales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
MMD2_k127_6003959_7	1122604.JONR01000006_gene2654	3.508e-168	572.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1X48I@135614|Xanthomonadales	135614|Xanthomonadales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
MMD2_k127_6003959_19	3659.XP_004151599.1	5.898e-74	274.0	COG1173@1|root,2SK3C@2759|Eukaryota	2759|Eukaryota	EP	nitrogen compound transport	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
MMD2_k127_6003959_12	1121935.AQXX01000140_gene1032	6.044e-119	395.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1XH9S@135619|Oceanospirillales	135619|Oceanospirillales	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
MMD2_k127_6003959_4	1280948.HY36_01935	5.132e-188	619.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,43X7Z@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMD2_k127_6003959_25	391615.ABSJ01000033_gene698	1.404e-48	181.0	COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,1SBJR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
MMD2_k127_6024864_6	661478.OP10G_0311	1.819e-90	308.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
MMD2_k127_6024864_1	864051.BurJ1DRAFT_0013	4.408e-215	676.0	COG0654@1|root,COG0654@2|Bacteria,1MXEW@1224|Proteobacteria,2VIVN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.218	ko:K20940	ko00405,ko01130,map00405,map01130	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
MMD2_k127_6024864_0	1340493.JNIF01000004_gene47	9.616e-225	702.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMD2_k127_6024864_7	1380355.JNIJ01000068_gene5658	2.348e-56	209.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria,3JTPW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TIR_2
MMD2_k127_6024864_3	627192.SLG_14350	5.315e-147	477.0	COG2271@1|root,COG2271@2|Bacteria,1P24P@1224|Proteobacteria,2URTW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major facilitator superfamily	-	-	-	ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4
MMD2_k127_6024864_2	627192.SLG_14250	1.161e-168	532.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TRG7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
MMD2_k127_6024864_4	1245471.PCA10_25710	9.099e-118	387.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,1YF1Q@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
MMD2_k127_6024864_5	627192.SLG_14340	1.542e-109	361.0	COG2197@1|root,COG2197@2|Bacteria,1R17I@1224|Proteobacteria,2UJU1@28211|Alphaproteobacteria,2KEP5@204457|Sphingomonadales	28211|Alphaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
MMD2_k127_6028512_0	1123368.AUIS01000023_gene933	8.673e-188	629.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_4
MMD2_k127_6028512_5	523791.Kkor_2302	8.844e-19	92.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin-like,DUF3494,TIG
MMD2_k127_6028512_1	396588.Tgr7_2340	1.268e-145	468.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1WWNR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMD2_k127_6028512_2	1123368.AUIS01000005_gene447	4.721e-104	356.0	COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,1RP34@1236|Gammaproteobacteria,2NBSM@225057|Acidithiobacillales	225057|Acidithiobacillales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
MMD2_k127_6028512_4	713586.KB900536_gene1280	1.085e-45	170.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WVVT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K07713,ko:K07715	ko02020,ko02024,map02020,map02024	M00499,M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD2_k127_6028512_3	1123487.KB892867_gene892	4.997e-87	293.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KVE6@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Sigma54_activat
MMD2_k127_6035747_1	740709.A10D4_11289	2.482e-97	323.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,2QFDF@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSFV_1184.SFV_1868	GAD,tRNA-synt_2,tRNA_anti-codon
MMD2_k127_6035747_2	1158150.KB906241_gene1299	7.851e-67	237.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria,1X29U@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
MMD2_k127_6035747_3	1500893.JQNB01000001_gene309	1.675e-26	113.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1X86G@135614|Xanthomonadales	135614|Xanthomonadales	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMD2_k127_6035747_0	765910.MARPU_07835	4.774e-290	900.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMD2_k127_6036307_6	519989.ECTPHS_03592	1.276e-119	402.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1WX8V@135613|Chromatiales	135613|Chromatiales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
MMD2_k127_6036307_10	566466.NOR53_3183	1.377e-91	327.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria	1224|Proteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_6036307_4	936455.KI421499_gene4673	2.229e-133	439.0	COG0654@1|root,COG0654@2|Bacteria,1N6PD@1224|Proteobacteria,2U19F@28211|Alphaproteobacteria,3JVN9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
MMD2_k127_6036307_0	1532558.JL39_16605	1.302e-220	697.0	COG0129@1|root,COG0129@2|Bacteria,1N6EG@1224|Proteobacteria,2U0FX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
MMD2_k127_6036307_11	1346791.M529_05385	4.426e-55	207.0	COG1786@1|root,COG1786@2|Bacteria,1RH5T@1224|Proteobacteria,2VGP4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
MMD2_k127_6036307_2	1346791.M529_05390	1.99e-173	554.0	COG1679@1|root,COG1679@2|Bacteria,1NFH4@1224|Proteobacteria,2TTR6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
MMD2_k127_6036307_9	420662.Mpe_A0906	7.044e-98	325.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,1KIXU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799,ko:K11209	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
MMD2_k127_6036307_1	1244869.H261_20210	8.846e-196	626.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JPZI@204441|Rhodospirillales	204441|Rhodospirillales	C	belongs to the aldehyde dehydrogenase family	puuC	-	1.2.1.54,1.2.1.99	ko:K09472,ko:K12254	ko00330,ko01100,map00330,map01100	M00136	R02549,R03177,R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMD2_k127_6036307_12	1452718.JBOY01000030_gene63	8.576e-18	95.0	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,1SDNA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K18301	-	M00642	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	TetR_C_7,TetR_N
MMD2_k127_6036307_5	378806.STAUR_6531	9.292e-125	417.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMD2_k127_6036307_3	880073.Calab_0510	1.041e-149	492.0	COG4992@1|root,COG4992@2|Bacteria,2NS3R@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-III	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
MMD2_k127_6036307_7	1128421.JAGA01000002_gene206	2.144e-119	396.0	COG1092@1|root,COG1092@2|Bacteria,2NPFM@2323|unclassified Bacteria	2|Bacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.191,2.1.1.264	ko:K06969,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
MMD2_k127_6036307_8	765911.Thivi_4167	4.445e-113	374.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1WWFG@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
MMD2_k127_6036307_13	47839.CCAU010000016_gene4434	6.555e-09	66.0	COG1309@1|root,COG1309@2|Bacteria,2HF0Z@201174|Actinobacteria,235MI@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMD2_k127_6049279_1	1121015.N789_13250	2.749e-123	401.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,1RSNG@1236|Gammaproteobacteria,1X6B5@135614|Xanthomonadales	135614|Xanthomonadales	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
MMD2_k127_6049279_3	1395516.PMO01_27645	1.105e-76	268.0	COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,1RZEY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	copper resistance	copB	-	-	ko:K07233	-	-	-	-	ko00000	-	-	-	CopB
MMD2_k127_6049279_0	1123020.AUIE01000001_gene2409	2.315e-239	752.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,1YCZP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Multicopper oxidase	copA	-	-	-	-	-	-	-	-	-	-	-	CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
MMD2_k127_6049279_2	713586.KB900536_gene2015	2.693e-102	356.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
MMD2_k127_6049279_4	1336233.JAEH01000055_gene4125	2.727e-28	126.0	COG0491@1|root,COG0491@2|Bacteria,1PBSA@1224|Proteobacteria,1SWGM@1236|Gammaproteobacteria,2QE2R@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_6056593_40	1298867.AUES01000002_gene1527	9.925e-26	125.0	COG0657@1|root,COG0657@2|Bacteria,1NA4A@1224|Proteobacteria,2U2SJ@28211|Alphaproteobacteria,3JX7P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMD2_k127_6056593_30	627192.SLG_31390	4.143e-58	220.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
MMD2_k127_6056593_16	234267.Acid_2032	1.3e-112	381.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_6056593_3	886293.Sinac_1153	2.321e-194	633.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_6056593_34	113395.AXAI01000001_gene3170	7.621e-46	179.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria,3JUHX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_6056593_4	1207063.P24_03835	1.746e-191	603.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,2JQ78@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
MMD2_k127_6056593_15	311402.Avi_5950	8.73e-123	412.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2VCNC@28211|Alphaproteobacteria,4BJVX@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Retinal pigment epithelial membrane protein	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
MMD2_k127_6056593_2	1117379.BABA_03459	1.542e-205	671.0	COG4993@1|root,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli,1ZFCQ@1386|Bacillus	91061|Bacilli	CG	COG4993 Glucose dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMD2_k127_6056593_1	1101191.KI912577_gene3112	1.636e-249	779.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,1JRY8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
MMD2_k127_6056593_47	105559.Nwat_1440	6.8e-06	53.0	295HK@1|root,2ZSV6@2|Bacteria,1P9TQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6056593_36	882.DVU_1585	9.786e-35	145.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2M9R7@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Methionine synthase B12-binding module cap domain protein	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
MMD2_k127_6056593_45	627192.SLG_27840	4.269e-14	85.0	COG4922@1|root,COG4922@2|Bacteria,1MYTU@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMD2_k127_6056593_39	864051.BurJ1DRAFT_1919	7.924e-28	128.0	COG4922@1|root,COG4922@2|Bacteria,1MYTU@1224|Proteobacteria,2WG68@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6056593_22	1120956.JHZK01000006_gene615	8.125e-95	317.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,1JPKX@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
MMD2_k127_6056593_14	400668.Mmwyl1_2755	8.704e-134	440.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XIU0@135619|Oceanospirillales	135619|Oceanospirillales	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
MMD2_k127_6056593_38	1144319.PMI16_00807	1.026e-28	126.0	COG1622@1|root,COG1622@2|Bacteria,1NEC9@1224|Proteobacteria,2VWA0@28216|Betaproteobacteria,477JR@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Cupredoxin-like domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1
MMD2_k127_6056593_13	1005048.CFU_1840	1.376e-134	439.0	COG1409@1|root,COG1409@2|Bacteria,1MUQJ@1224|Proteobacteria,2VJNP@28216|Betaproteobacteria,475EI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
MMD2_k127_6056593_32	1169143.KB911035_gene2398	1.616e-49	184.0	COG1595@1|root,COG1595@2|Bacteria,1PT8E@1224|Proteobacteria,2W1XX@28216|Betaproteobacteria,1K2WI@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_6056593_29	485913.Krac_10225	1.16e-58	213.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMD2_k127_6056593_25	1209072.ALBT01000046_gene2593	1.041e-83	288.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_6056593_21	640511.BC1002_5978	1.931e-96	326.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2VKR0@28216|Betaproteobacteria,1K2I8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
MMD2_k127_6056593_9	1216976.AX27061_5207	1.36e-145	498.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2VHIZ@28216|Betaproteobacteria,3T9KQ@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMD2_k127_6056593_8	1120983.KB894574_gene927	4.207e-152	503.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TRM1@28211|Alphaproteobacteria,1JQMN@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
MMD2_k127_6056593_18	1120983.KB894574_gene926	3.227e-112	373.0	COG1638@1|root,COG1638@2|Bacteria,1MUJY@1224|Proteobacteria,2TQNU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
MMD2_k127_6056593_12	648757.Rvan_1614	1.221e-142	479.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,3N642@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
MMD2_k127_6056593_17	1123073.KB899244_gene445	1.921e-112	372.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1X33N@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMD2_k127_6056593_20	1042377.AFPJ01000051_gene33	3.78e-97	339.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_6056593_49	1479235.KK366039_gene2934	0.0002844	47.0	COG3630@1|root,COG3630@2|Bacteria,1NHYS@1224|Proteobacteria,1SGS8@1236|Gammaproteobacteria,1XM8S@135619|Oceanospirillales	135619|Oceanospirillales	C	Lyase and sodium transporter	oadG	-	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
MMD2_k127_6056593_0	349521.HCH_05202	1.372e-254	798.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XIFS@135619|Oceanospirillales	135619|Oceanospirillales	CI	Oxaloacetate decarboxylase	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
MMD2_k127_6056593_6	765910.MARPU_07645	1.549e-167	535.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1WVXS@135613|Chromatiales	135613|Chromatiales	C	decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
MMD2_k127_6056593_42	1236959.BAMT01000015_gene2850	7.383e-23	113.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6056593_41	1165096.ARWF01000001_gene441	1.447e-25	112.0	2BUQD@1|root,32Q1F@2|Bacteria,1PJPP@1224|Proteobacteria,2W83R@28216|Betaproteobacteria,2KNSW@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6056593_33	1121939.L861_08755	6.575e-48	189.0	COG0457@1|root,COG0457@2|Bacteria,1PEMT@1224|Proteobacteria,1S5W3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
MMD2_k127_6056593_26	1042375.AFPL01000008_gene3328	3.957e-78	272.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,1RTD3@1236|Gammaproteobacteria,468ZK@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein F	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
MMD2_k127_6056593_19	644801.Psest_2618	6.604e-99	332.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S1QN@1236|Gammaproteobacteria,1YZYE@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	U	Flp pilus assembly protein TadB	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
MMD2_k127_6056593_5	644801.Psest_2619	1.432e-183	591.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1Z180@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	U	pilus assembly protein, ATPase CpaF	tadA	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
MMD2_k127_6056593_27	1232683.ADIMK_0481	1.448e-76	276.0	COG2199@1|root,COG4963@1|root,COG3706@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,1S6CE@1236|Gammaproteobacteria,469IJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
MMD2_k127_6056593_37	477228.YO5_15620	3.917e-29	125.0	COG4961@1|root,COG4961@2|Bacteria,1N2QC@1224|Proteobacteria,1TC3C@1236|Gammaproteobacteria,1Z320@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
MMD2_k127_6056593_35	472759.Nhal_1423	1.908e-37	145.0	COG4961@1|root,COG4961@2|Bacteria,1NCGE@1224|Proteobacteria,1SDQ1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
MMD2_k127_6056593_23	1318628.MARLIPOL_12729	4.177e-90	313.0	COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria,46AQ4@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
MMD2_k127_6056593_10	472759.Nhal_1420	1.777e-145	479.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,1X10W@135613|Chromatiales	135613|Chromatiales	U	Pilus formation protein N terminal region	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Secretin,T2SS-T3SS_pil_N
MMD2_k127_6056593_28	1215092.PA6_007_00040	5.297e-66	233.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,1S6EP@1236|Gammaproteobacteria,1YKM0@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	U	Flp pilus assembly protein RcpC/CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
MMD2_k127_6056593_11	1163398.AJJP01000169_gene1161	1.209e-143	473.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,1RZBX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6056593_43	1136138.JH604623_gene3261	5.724e-17	89.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	cpaA	-	3.4.23.43	ko:K02278,ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
MMD2_k127_6056593_46	644801.Psest_2629	7.952e-09	59.0	2BKJY@1|root,32F16@2|Bacteria,1QDSQ@1224|Proteobacteria,1T9W3@1236|Gammaproteobacteria,1Z3NR@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	-	-	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
MMD2_k127_6056593_31	472759.Nhal_1415	7.509e-51	190.0	COG2204@1|root,COG2207@1|root,COG2204@2|Bacteria,COG2207@2|Bacteria,1N1CY@1224|Proteobacteria,1SBMK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,PocR,Response_reg,Sigma54_activ_2
MMD2_k127_6056593_7	1123257.AUFV01000003_gene875	1.128e-153	497.0	COG2133@1|root,COG3474@1|root,COG2133@2|Bacteria,COG3474@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1X59I@135614|Xanthomonadales	135614|Xanthomonadales	CG	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH
MMD2_k127_6056593_48	1134912.AJTV01000029_gene2048	9.489e-06	59.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,36ZA7@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_612370_13	157783.LK03_09990	2.387e-57	203.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
MMD2_k127_612370_11	1211114.ALIP01000091_gene2865	1.549e-65	226.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1X61V@135614|Xanthomonadales	135614|Xanthomonadales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
MMD2_k127_612370_12	267608.RSc2854	3.233e-60	216.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,1K1RC@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
MMD2_k127_612370_9	523791.Kkor_0153	5.678e-81	275.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1XH7Z@135619|Oceanospirillales	135619|Oceanospirillales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
MMD2_k127_612370_15	314278.NB231_11669	7.212e-53	198.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1WY9S@135613|Chromatiales	135613|Chromatiales	O	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host	djlA	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
MMD2_k127_612370_3	572477.Alvin_2538	1.751e-121	399.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1WVZH@135613|Chromatiales	135613|Chromatiales	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
MMD2_k127_612370_6	748658.KB907313_gene2292	1.362e-98	339.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales	135613|Chromatiales	K	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
MMD2_k127_612370_2	314278.NB231_05806	4.462e-139	454.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1WWPA@135613|Chromatiales	135613|Chromatiales	S	modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMD2_k127_612370_10	309801.trd_0646	5.665e-69	237.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi,27YJ0@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
MMD2_k127_612370_4	589865.DaAHT2_1509	5.784e-113	375.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,42PQI@68525|delta/epsilon subdivisions,2WKZR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp
MMD2_k127_612370_7	396588.Tgr7_2396	2.514e-95	328.0	COG1716@1|root,COG3267@1|root,COG1716@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1WWX7@135613|Chromatiales	135613|Chromatiales	U	Type II secretory pathway component ExeA	-	-	-	ko:K02450,ko:K12283	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
MMD2_k127_612370_0	1384056.N787_10090	4.547e-193	613.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1X3N2@135614|Xanthomonadales	135614|Xanthomonadales	S	Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMD2_k127_612370_8	713586.KB900536_gene1089	2.467e-83	288.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1WW30@135613|Chromatiales	135613|Chromatiales	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
MMD2_k127_612370_5	1121015.N789_05830	1.558e-110	400.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1X37J@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
MMD2_k127_612370_1	713586.KB900536_gene1092	3.94e-190	614.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
MMD2_k127_612370_14	1042876.PPS_0966	5.693e-54	196.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1YVEB@136845|Pseudomonas putida group	1236|Gammaproteobacteria	D	Maf-like protein	yhdE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
MMD2_k127_6166009_1	1095769.CAHF01000011_gene2142	1.24e-122	407.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,472S7@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	TonB dependent receptor	yncD	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_6166009_3	929556.Solca_2079	3.38e-18	100.0	28PD0@1|root,2ZC53@2|Bacteria,4NM6X@976|Bacteroidetes,1IRX2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6166009_2	1094184.KWO_0119915	1.348e-29	130.0	COG2207@1|root,COG2207@2|Bacteria,1MXT9@1224|Proteobacteria,1SYHU@1236|Gammaproteobacteria,1X86Y@135614|Xanthomonadales	135614|Xanthomonadales	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
MMD2_k127_6166009_0	1522072.IL54_1423	1.149e-175	578.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_6210730_0	583355.Caka_2558	2.261e-227	717.0	COG0442@1|root,COG0442@2|Bacteria,46SE3@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
MMD2_k127_6210730_4	682795.AciX8_0601	5.343e-48	183.0	COG2095@1|root,COG2095@2|Bacteria,3Y429@57723|Acidobacteria,2JI6F@204432|Acidobacteriia	204432|Acidobacteriia	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
MMD2_k127_6210730_7	1267534.KB906755_gene4131	2.946e-24	106.0	COG3801@1|root,COG3801@2|Bacteria	2|Bacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
MMD2_k127_6210730_5	323848.Nmul_A1375	8.435e-33	143.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VU64@28216|Betaproteobacteria,3738I@32003|Nitrosomonadales	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
MMD2_k127_6210730_2	391625.PPSIR1_41609	1.068e-60	222.0	KOG1584@1|root,32BW5@2|Bacteria,1PW91@1224|Proteobacteria,42YNQ@68525|delta/epsilon subdivisions,2WTQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
MMD2_k127_6210730_1	396588.Tgr7_0241	3.963e-150	500.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,1RQYX@1236|Gammaproteobacteria,1X2PP@135613|Chromatiales	135613|Chromatiales	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_6210730_3	1197906.CAJQ02000020_gene409	1.409e-60	215.0	COG0861@1|root,COG0861@2|Bacteria,1PN8B@1224|Proteobacteria,2TUV5@28211|Alphaproteobacteria,3JTV7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Integral membrane protein TerC family	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
MMD2_k127_6210730_6	550540.Fbal_0105	2.215e-27	118.0	COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,1T1K4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
MMD2_k127_6210730_8	765910.MARPU_10495	2.943e-06	53.0	2DQWF@1|root,3392H@2|Bacteria,1N93V@1224|Proteobacteria,1SFNS@1236|Gammaproteobacteria,1WZ6Y@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
MMD2_k127_6210730_9	118168.MC7420_3147	0.0003014	47.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1H71S@1150|Oscillatoriales	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
MMD2_k127_6231575_1	748658.KB907312_gene1816	4.1e-97	325.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales	135613|Chromatiales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
MMD2_k127_6231575_2	1380394.JADL01000017_gene488	3.231e-65	247.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,2JPM6@204441|Rhodospirillales	204441|Rhodospirillales	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMD2_k127_6231575_5	1238182.C882_2255	2.079e-34	144.0	COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,2VGN6@28211|Alphaproteobacteria,2JUV4@204441|Rhodospirillales	204441|Rhodospirillales	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
MMD2_k127_6231575_7	267608.RSc0939	2.741e-16	91.0	2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,2VX2T@28216|Betaproteobacteria,1K8JC@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
MMD2_k127_6231575_3	1121445.ATUZ01000015_gene1751	8.721e-56	205.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,2M9V0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
MMD2_k127_6231575_0	555778.Hneap_1159	2.226e-137	451.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1WW9F@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD2_k127_6231575_6	760568.Desku_1853	1.274e-32	134.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,2623G@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
MMD2_k127_6231575_4	404589.Anae109_0373	6.816e-46	177.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,2YV8U@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
MMD2_k127_625840_3	396588.Tgr7_3031	1.08e-129	422.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
MMD2_k127_625840_8	395961.Cyan7425_1987	7.807e-70	245.0	COG0284@1|root,COG0284@2|Bacteria,1G2ED@1117|Cyanobacteria,3KGCY@43988|Cyanothece	1117|Cyanobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
MMD2_k127_625840_6	861299.J421_3829	3.264e-82	298.0	COG2733@1|root,COG2733@2|Bacteria,1ZTAK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
MMD2_k127_625840_2	1442599.JAAN01000021_gene2306	8.598e-207	659.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X3W8@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Activates fatty acids by binding to coenzyme A	rpfB	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMD2_k127_625840_10	1122139.KB907869_gene936	3.602e-56	207.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1XJIV@135619|Oceanospirillales	135619|Oceanospirillales	E	COG2755 Lysophospholipase L1 and related esterases	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
MMD2_k127_625840_7	1300345.LF41_2553	4.012e-82	278.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1X508@135614|Xanthomonadales	135614|Xanthomonadales	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_625840_5	713586.KB900536_gene98	1.498e-92	314.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1WW4Q@135613|Chromatiales	135613|Chromatiales	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMD2_k127_625840_11	926569.ANT_10560	6.288e-55	198.0	COG2983@1|root,COG2983@2|Bacteria	2|Bacteria	S	Putative zinc- or iron-chelating domain	MA20_15575	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
MMD2_k127_625840_0	743721.Psesu_0497	1.536e-257	822.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1X4MI@135614|Xanthomonadales	135614|Xanthomonadales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
MMD2_k127_625840_1	1232410.KI421415_gene3088	1.647e-247	779.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,42PQK@68525|delta/epsilon subdivisions,2WJCT@28221|Deltaproteobacteria,43T12@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMD2_k127_625840_4	292459.STH1407	4.524e-122	407.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
MMD2_k127_625840_9	264732.Moth_1341	2.561e-67	246.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,42G1H@68295|Thermoanaerobacterales	186801|Clostridia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMD2_k127_625840_12	562970.Btus_1721	4.871e-45	180.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,2781D@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
MMD2_k127_625840_13	3659.XP_004152482.1	5.922e-15	77.0	COG0547@1|root,KOG1438@2759|Eukaryota,37KW6@33090|Viridiplantae,3GDTU@35493|Streptophyta,4JK8E@91835|fabids	35493|Streptophyta	E	Anthranilate phosphoribosyltransferase	-	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0031967,GO:0031975,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
MMD2_k127_6260344_42	118161.KB235922_gene4646	1.851e-71	252.0	COG1028@1|root,COG1028@2|Bacteria,1G2ZD@1117|Cyanobacteria,3VM8E@52604|Pleurocapsales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMD2_k127_6260344_81	522373.Smlt0551	8.097e-11	65.0	COG2199@1|root,COG2200@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2J6@1236|Gammaproteobacteria,1X540@135614|Xanthomonadales	135614|Xanthomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_8
MMD2_k127_6260344_56	426355.Mrad2831_4100	4.649e-54	203.0	COG0671@1|root,COG0671@2|Bacteria,1RJT1@1224|Proteobacteria,2U99G@28211|Alphaproteobacteria,1JSQS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM phosphoesterase PA-phosphatase related	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.1.3.2	ko:K09474	ko00740,ko01100,ko02020,map00740,map01100,map02020	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	PAP2
MMD2_k127_6260344_66	1109445.AGSX01000078_gene656	4.04e-30	128.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,1T06D@1236|Gammaproteobacteria,1Z1W0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
MMD2_k127_6260344_31	1158292.JPOE01000005_gene1060	5.878e-90	301.0	COG2755@1|root,COG2755@2|Bacteria,1RDVJ@1224|Proteobacteria,2VHK1@28216|Betaproteobacteria	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMD2_k127_6260344_76	1380394.JADL01000001_gene3007	1.618e-13	79.0	COG2350@1|root,COG2350@2|Bacteria,1PUAX@1224|Proteobacteria,2VC91@28211|Alphaproteobacteria,2JY6D@204441|Rhodospirillales	204441|Rhodospirillales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMD2_k127_6260344_8	279714.FuraDRAFT_0071	2.991e-171	559.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,2KPED@206351|Neisseriales	206351|Neisseriales	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
MMD2_k127_6260344_57	1279019.ARQK01000041_gene479	5.038e-53	193.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1X0ZV@135613|Chromatiales	135613|Chromatiales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
MMD2_k127_6260344_74	391625.PPSIR1_17550	4.407e-14	78.0	2E6K6@1|root,3316Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6260344_27	1244869.H261_19913	4.818e-98	328.0	COG0437@1|root,COG0437@2|Bacteria,1R6XQ@1224|Proteobacteria	1224|Proteobacteria	C	Pyrogallol hydroxytransferase	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Fer4_11
MMD2_k127_6260344_2	1244869.H261_19918	0.0	1362.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TSAP@28211|Alphaproteobacteria,2JRAB@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
MMD2_k127_6260344_3	1244869.H261_05239	0.0	1113.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VF1V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NAD_binding_1
MMD2_k127_6260344_0	243233.MCA0335	0.0	1656.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1PE6F@1224|Proteobacteria,1RWQP@1236|Gammaproteobacteria,1XDNM@135618|Methylococcales	135618|Methylococcales	CEH	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
MMD2_k127_6260344_7	497321.C664_15668	3.064e-175	559.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VI4U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B	ligB	-	1.13.11.57	ko:K04099	ko00627,ko01120,map00627,map01120	-	R03550,R04280,R09565	RC00233,RC00535,RC02567,RC02694	ko00000,ko00001,ko01000	-	-	-	LigA,LigB
MMD2_k127_6260344_14	266117.Rxyl_2476	3.935e-140	458.0	COG2271@1|root,COG2271@2|Bacteria,2GIS1@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_6260344_22	1234364.AMSF01000024_gene3824	4.608e-101	334.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,1RS0R@1236|Gammaproteobacteria,1XC7H@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative vitamin uptake transporter	-	-	-	-	-	-	-	-	-	-	-	-	Vut_1
MMD2_k127_6260344_6	395493.BegalDRAFT_0778	1.496e-207	698.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4607X@72273|Thiotrichales	72273|Thiotrichales	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
MMD2_k127_6260344_60	745411.B3C1_07304	2.152e-50	186.0	COG1047@1|root,COG1047@2|Bacteria,1RGXG@1224|Proteobacteria,1S6XS@1236|Gammaproteobacteria,1J661@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2	slyD1	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
MMD2_k127_6260344_83	1184267.A11Q_1141	2.913e-09	62.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria	1224|Proteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMD2_k127_6260344_47	349521.HCH_03562	1.511e-63	230.0	28MWZ@1|root,2ZB46@2|Bacteria,1R7K6@1224|Proteobacteria,1SQ6M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6260344_52	1123277.KB893179_gene3151	3.201e-60	226.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47XN3@768503|Cytophagia	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMD2_k127_6260344_16	1411123.JQNH01000001_gene3657	1.154e-133	456.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	MA20_17495	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
MMD2_k127_6260344_50	1121374.KB891578_gene3269	1.325e-61	241.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2K9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_6260344_9	1499689.CCNN01000007_gene2233	6.133e-163	525.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,36H5G@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	sucD	-	1.2.1.76,1.2.1.87	ko:K13922,ko:K18119	ko00640,ko00650,ko01100,ko01200,map00640,map00650,map01100,map01200	-	R09097,R09280	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMD2_k127_6260344_36	1238182.C882_3470	7.527e-80	274.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2TUFR@28211|Alphaproteobacteria,2JRU5@204441|Rhodospirillales	204441|Rhodospirillales	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMD2_k127_6260344_82	322710.Avin_33810	1.518e-09	66.0	2E94M@1|root,333DG@2|Bacteria,1ND0P@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6260344_84	1081640.AGFU01000005_gene1127	1.742e-08	63.0	COG0346@1|root,COG1073@1|root,COG0346@2|Bacteria,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2TVHP@28211|Alphaproteobacteria,2K0QE@204457|Sphingomonadales	204457|Sphingomonadales	E	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Peptidase_S9
MMD2_k127_6260344_25	1088721.NSU_3344	9.888e-100	337.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2VFRT@28211|Alphaproteobacteria,2KDYK@204457|Sphingomonadales	204457|Sphingomonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMD2_k127_6260344_73	1411685.U062_00937	1.341e-20	101.0	COG0625@1|root,COG0625@2|Bacteria,1MWUG@1224|Proteobacteria	1224|Proteobacteria	O	Glutathione S-transferase	gst	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_3
MMD2_k127_6260344_35	234267.Acid_7390	2.032e-84	286.0	COG1028@1|root,COG1028@2|Bacteria,3Y6I4@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
MMD2_k127_6260344_88	32057.KB217483_gene9377	0.0004812	53.0	COG2133@1|root,COG2133@2|Bacteria,1G2QD@1117|Cyanobacteria,1HP83@1161|Nostocales	1117|Cyanobacteria	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
MMD2_k127_6260344_79	118173.KB235914_gene835	1.191e-12	69.0	COG2133@1|root,COG2133@2|Bacteria,1G2QD@1117|Cyanobacteria,1H7CA@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
MMD2_k127_6260344_72	1134912.AJTV01000029_gene2048	8.612e-22	110.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,36ZA7@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_6260344_4	335283.Neut_2269	1.213e-243	777.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,373XP@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
MMD2_k127_6260344_37	1380394.JADL01000001_gene2053	1.108e-79	279.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,2TR82@28211|Alphaproteobacteria,2JQNP@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
MMD2_k127_6260344_44	768671.ThimaDRAFT_3322	2.739e-69	246.0	COG1985@1|root,COG1985@2|Bacteria,1RES9@1224|Proteobacteria,1S3BT@1236|Gammaproteobacteria,1WYR6@135613|Chromatiales	135613|Chromatiales	H	RibD C-terminal domain	-	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
MMD2_k127_6260344_80	1122613.ATUP01000001_gene2290	3.735e-12	78.0	COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,2UEEK@28211|Alphaproteobacteria,43XZ3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMD2_k127_6260344_71	1328313.DS2_00280	8.291e-22	102.0	COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria,46CF3@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD2_k127_6260344_48	1266908.AQPB01000048_gene2156	3.465e-62	229.0	COG4123@1|root,COG4123@2|Bacteria,1QYGW@1224|Proteobacteria,1S7AI@1236|Gammaproteobacteria,1WYRD@135613|Chromatiales	135613|Chromatiales	S	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6260344_21	1123504.JQKD01000008_gene5344	3.286e-101	342.0	COG0438@1|root,COG0438@2|Bacteria,1P81Z@1224|Proteobacteria,2VQRF@28216|Betaproteobacteria,4AJ0Z@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMD2_k127_6260344_54	1238182.C882_0778	6.721e-59	207.0	COG0720@1|root,COG0720@2|Bacteria,1RI8E@1224|Proteobacteria,2U8NH@28211|Alphaproteobacteria,2JSU3@204441|Rhodospirillales	204441|Rhodospirillales	H	6-pyruvoyl tetrahydropterin synthase	-	-	-	-	-	-	-	-	-	-	-	-	PTPS
MMD2_k127_6260344_17	768671.ThimaDRAFT_3326	4.571e-126	411.0	COG1063@1|root,COG1063@2|Bacteria,1MW7C@1224|Proteobacteria,1RYJU@1236|Gammaproteobacteria,1WYA7@135613|Chromatiales	135613|Chromatiales	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,NAD_binding_8
MMD2_k127_6260344_64	1348657.M622_06555	3.025e-44	172.0	COG0558@1|root,COG0558@2|Bacteria,1N1AE@1224|Proteobacteria,2W338@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
MMD2_k127_6260344_24	1348657.M622_06510	5.089e-100	347.0	COG0558@1|root,COG0558@2|Bacteria,1QVT7@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6260344_69	1121937.AUHJ01000012_gene2803	4.862e-24	117.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,4653Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD2_k127_6260344_32	448385.sce1808	4.444e-89	302.0	COG2242@1|root,COG2242@2|Bacteria,1RCBZ@1224|Proteobacteria,430EM@68525|delta/epsilon subdivisions,2WW2Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
MMD2_k127_6260344_46	1230343.CANP01000021_gene1428	8.327e-66	236.0	COG0121@1|root,COG0121@2|Bacteria,1QCFK@1224|Proteobacteria,1RPUW@1236|Gammaproteobacteria,1JGIK@118969|Legionellales	118969|Legionellales	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
MMD2_k127_6260344_67	639283.Snov_4052	1.211e-24	108.0	COG2005@1|root,COG2005@2|Bacteria,1P9SX@1224|Proteobacteria,2UC9Q@28211|Alphaproteobacteria,3EZWA@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Bacterial regulatory helix-turn-helix protein, lysR family	modE	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
MMD2_k127_6260344_34	1123393.KB891326_gene101	8.73e-86	290.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
MMD2_k127_6260344_26	335543.Sfum_3898	2.017e-98	334.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42NWJ@68525|delta/epsilon subdivisions,2WKW7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase, class I	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_6260344_12	288000.BBta_7809	1.072e-142	471.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TS6B@28211|Alphaproteobacteria,3JUYU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Trypsin	-	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
MMD2_k127_6260344_61	309807.SRU_1922	4.248e-47	177.0	COG4089@1|root,COG4089@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
MMD2_k127_6260344_49	565033.GACE_0682	5.587e-62	222.0	COG0730@1|root,arCOG09610@2157|Archaea	2157|Archaea	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD2_k127_6260344_65	911045.PSE_2326	2.519e-39	160.0	COG3386@1|root,COG3386@2|Bacteria,1MXB7@1224|Proteobacteria,2U2RZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMD2_k127_6260344_19	1172179.AUKV01000009_gene4494	5.44e-124	412.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6260344_13	243233.MCA3025	2.288e-142	480.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria,1XDVS@135618|Methylococcales	135618|Methylococcales	C	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
MMD2_k127_6260344_86	309798.COPRO5265_1300	3.229e-06	59.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,42FUD@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
MMD2_k127_6260344_15	998674.ATTE01000001_gene4311	2.417e-136	440.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,4621A@72273|Thiotrichales	72273|Thiotrichales	S	MCM2/3/5 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
MMD2_k127_6260344_40	395493.BegalDRAFT_0160	2.975e-74	263.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,460QI@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMD2_k127_6260344_68	857087.Metme_0110	3.804e-24	111.0	COG2304@1|root,COG2304@2|Bacteria,1QVQA@1224|Proteobacteria,1S9W8@1236|Gammaproteobacteria,1XFBG@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4381)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4381
MMD2_k127_6260344_20	697282.Mettu_1929	2.533e-110	370.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XDQK@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
MMD2_k127_6260344_18	697282.Mettu_1928	2.66e-124	423.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XEC7@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_2,VWA_2
MMD2_k127_6260344_41	686340.Metal_0122	4.204e-72	268.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1XEJY@135618|Methylococcales	135618|Methylococcales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
MMD2_k127_6260344_51	1215092.PA6_008_01260	1.761e-61	227.0	COG2199@1|root,COG3706@2|Bacteria,1RDWG@1224|Proteobacteria,1S7W2@1236|Gammaproteobacteria,1YEDJ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMD2_k127_6260344_45	266779.Meso_1734	4.96e-69	235.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,43JP2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	gloA	GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
MMD2_k127_6260344_59	580332.Slit_2150	8.135e-52	195.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6260344_29	1121374.KB891576_gene458	5.888e-93	325.0	COG2885@1|root,COG2885@2|Bacteria,1P1AB@1224|Proteobacteria,1RMCQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	oprF	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMD2_k127_6260344_55	1123519.PSJM300_11555	1.27e-55	200.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1Z0ZG@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
MMD2_k127_6260344_10	1304275.C41B8_13240	5.998e-154	493.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
MMD2_k127_6260344_28	472759.Nhal_2669	1.106e-95	329.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,1WWN7@135613|Chromatiales	135613|Chromatiales	OU	PFAM peptidase	-	-	-	ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49,Peptidase_S49_N
MMD2_k127_6260344_62	342610.Patl_1689	4.739e-47	180.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,1S8IP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Peptidase_M23
MMD2_k127_6260344_33	768671.ThimaDRAFT_0614	2.813e-88	309.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1WXGI@135613|Chromatiales	135613|Chromatiales	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	SPOR,YkuD
MMD2_k127_6260344_38	1121033.AUCF01000009_gene1133	3.46e-77	265.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,2JRGA@204441|Rhodospirillales	204441|Rhodospirillales	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMD2_k127_6260344_53	1521187.JPIM01000011_gene2628	3.284e-59	225.0	COG3497@1|root,COG3497@2|Bacteria,2G7YJ@200795|Chloroflexi,37730@32061|Chloroflexia	32061|Chloroflexia	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
MMD2_k127_6260344_58	292415.Tbd_1055	5.125e-53	196.0	COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria,2VTFD@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMD2_k127_6260344_1	414684.RC1_0628	0.0	1364.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JQPR@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
MMD2_k127_6260344_70	204773.HEAR1950	5.633e-24	107.0	COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,2VUSU@28216|Betaproteobacteria,474ZQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10924	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
MMD2_k127_6260344_23	1215114.BBIU01000007_gene1113	5.192e-101	344.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
MMD2_k127_6260344_87	666685.R2APBS1_3499	1.096e-05	50.0	2AE1E@1|root,313U4@2|Bacteria,1QD5W@1224|Proteobacteria,1T926@1236|Gammaproteobacteria,1XBJV@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_6260344_39	1244869.H261_21581	5.721e-77	271.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2U0CA@28211|Alphaproteobacteria,2JS5Q@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
MMD2_k127_6260344_75	396588.Tgr7_3049	1.476e-13	73.0	COG5481@1|root,COG5481@2|Bacteria	2|Bacteria	S	small protein containing a coiled-coil domain	MA20_03740	-	-	-	-	-	-	-	-	-	-	-	DUF465
MMD2_k127_6260344_30	243233.MCA2983	1.678e-92	316.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XF6C@135618|Methylococcales	135618|Methylococcales	P	Inositol monophosphatase family	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
MMD2_k127_6260344_43	1122201.AUAZ01000006_gene3888	1.055e-69	244.0	COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,466G1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Haloacid dehalogenase-like hydrolase	yrfG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
MMD2_k127_6260344_11	765913.ThidrDRAFT_1567	1.925e-152	495.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales	135613|Chromatiales	L	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
MMD2_k127_6260344_63	1158756.AQXQ01000011_gene661	1.273e-46	172.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1WYTD@135613|Chromatiales	135613|Chromatiales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
MMD2_k127_6260344_5	1260251.SPISAL_08215	1.362e-228	715.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1WW22@135613|Chromatiales	135613|Chromatiales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
MMD2_k127_673513_0	46429.BV95_03612	1.159e-73	276.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3JH@28211|Alphaproteobacteria,2K1GK@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
MMD2_k127_673513_3	1150599.MPHLEI_19784	1.587e-16	93.0	COG5517@1|root,COG5517@2|Bacteria,2GR5G@201174|Actinobacteria,236F8@1762|Mycobacteriaceae	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_673513_2	1172185.KB911512_gene5041	7.104e-27	121.0	COG5517@1|root,COG5517@2|Bacteria,2GR5G@201174|Actinobacteria,4G0XR@85025|Nocardiaceae	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_673513_1	314287.GB2207_03045	9.678e-67	244.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria,1JAB2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3202 ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
MMD2_k127_803700_4	765910.MARPU_07835	3.829e-173	548.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMD2_k127_803700_15	765912.Thimo_2185	1.063e-69	258.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1WX0I@135613|Chromatiales	135613|Chromatiales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
MMD2_k127_803700_11	83406.HDN1F_03400	2.676e-112	371.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1J54T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	PseudoU_synth_2,S4
MMD2_k127_803700_18	1469245.JFBG01000098_gene1361	2.155e-54	205.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1WX6S@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
MMD2_k127_803700_3	519989.ECTPHS_01999	3.186e-192	622.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1WWS1@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
MMD2_k127_803700_9	396588.Tgr7_0810	1.707e-135	445.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1WW8G@135613|Chromatiales	135613|Chromatiales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
MMD2_k127_803700_8	713586.KB900536_gene1350	8.202e-151	495.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales	135613|Chromatiales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
MMD2_k127_803700_12	472759.Nhal_0597	1.558e-111	382.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X2Q0@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
MMD2_k127_803700_5	472759.Nhal_0598	3.863e-168	540.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WVVT@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD2_k127_803700_20	1121921.KB898706_gene2722	2.184e-45	169.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,2PNZB@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	NU	Pilin (bacterial filament)	pilA	-	-	ko:K02650,ko:K02655	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
MMD2_k127_803700_23	1121921.KB898706_gene2722	1.312e-17	93.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,2PNZB@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	NU	Pilin (bacterial filament)	pilA	-	-	ko:K02650,ko:K02655	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
MMD2_k127_803700_1	314278.NB231_05511	2.51e-233	734.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
MMD2_k127_803700_7	1116472.MGMO_45c00640	8.329e-156	501.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1XE3Q@135618|Methylococcales	135618|Methylococcales	U	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
MMD2_k127_803700_13	1049564.TevJSym_ai00310	6.501e-98	329.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1J5E9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02464,ko:K02654	ko03070,map03070	M00331	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
MMD2_k127_803700_19	1121035.AUCH01000016_gene2149	3.564e-47	189.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,2KW4Z@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
MMD2_k127_803700_17	472759.Nhal_3851	8.056e-56	206.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1WWH6@135613|Chromatiales	135613|Chromatiales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
MMD2_k127_803700_22	1112217.PPL19_21685	6.389e-30	128.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	belongs to the nudix hydrolase family	mutT	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129	NUDIX,NUDIX_4,TMP-TENI
MMD2_k127_803700_0	472759.Nhal_0500	0.0	1145.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
MMD2_k127_803700_14	1121921.KB898706_gene2713	2.692e-82	284.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,2PMP4@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMD2_k127_803700_10	1215092.PA6_020_00960	1.752e-119	393.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1YE1N@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECS88_1305.ECS88_0100	LpxC
MMD2_k127_803700_6	713586.KB900536_gene1367	3.321e-160	512.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMD2_k127_803700_2	396588.Tgr7_0774	5.47e-203	638.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales	135613|Chromatiales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
MMD2_k127_803700_21	1226994.AMZB01000100_gene1011	5.185e-39	159.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1YEMS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
MMD2_k127_803700_16	396588.Tgr7_0771	2.132e-62	218.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
MMD2_k127_823457_5	935261.JAGL01000004_gene867	2.836e-24	106.0	COG3384@1|root,COG3384@2|Bacteria	2|Bacteria	S	3-carboxyethylcatechol 2,3-dioxygenase activity	-	-	1.13.11.8	ko:K04100	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA
MMD2_k127_823457_0	935261.JAGL01000004_gene868	1.44e-107	361.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,43J3C@69277|Phyllobacteriaceae	1224|Proteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
MMD2_k127_823457_2	114615.BRADO5603	1.033e-86	294.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2TRJT@28211|Alphaproteobacteria,3JW10@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	MA20_02555	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
MMD2_k127_823457_1	566466.NOR53_3709	6.93e-106	351.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RS05@1236|Gammaproteobacteria,1J4JW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMD2_k127_823457_7	279714.FuraDRAFT_3733	4.156e-11	71.0	COG3103@1|root,COG3103@2|Bacteria,1QVCP@1224|Proteobacteria	1224|Proteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_823457_3	1254432.SCE1572_04735	4.97e-74	260.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,42SVA@68525|delta/epsilon subdivisions,2WPFH@28221|Deltaproteobacteria,2Z1X4@29|Myxococcales	28221|Deltaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMD2_k127_823457_4	1380394.JADL01000011_gene3905	1.095e-65	227.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JPPV@204441|Rhodospirillales	204441|Rhodospirillales	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMD2_k127_851183_32	1121924.ATWH01000004_gene2312	4.617e-41	164.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4FRRA@85023|Microbacteriaceae	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMD2_k127_851183_30	357808.RoseRS_2516	1.437e-42	171.0	COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,377RE@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Methionine synthase, vitamin-B12 independent	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMD2_k127_851183_4	1381123.AYOD01000010_gene294	8.066e-195	624.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRI3@28211|Alphaproteobacteria,43NFB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.67	ko:K21802	ko00627,ko01120,map00627,map01120	-	R05699	RC00075	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMD2_k127_851183_20	565045.NOR51B_1350	9.395e-90	315.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
MMD2_k127_851183_26	1033802.SSPSH_000074	2.502e-54	191.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF1971,DUF3470,Fer4
MMD2_k127_851183_39	1121937.AUHJ01000001_gene423	4.621e-32	128.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1T0DU@1236|Gammaproteobacteria,46CKS@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
MMD2_k127_851183_3	1238182.C882_1234	2.126e-224	714.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,2JSY5@204441|Rhodospirillales	204441|Rhodospirillales	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
MMD2_k127_851183_11	1234595.C725_0898	2.523e-127	429.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	MA20_01040	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
MMD2_k127_851183_12	1282876.BAOK01000002_gene891	2.115e-113	380.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,4BRV7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMD2_k127_851183_2	1279038.KB907341_gene1761	2.297e-262	818.0	COG2807@1|root,COG2807@2|Bacteria,1QU0F@1224|Proteobacteria,2TTB4@28211|Alphaproteobacteria,2JPWW@204441|Rhodospirillales	204441|Rhodospirillales	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_851183_41	713586.KB900536_gene552	4.22e-28	129.0	COG1404@1|root,COG1653@1|root,COG1404@2|Bacteria,COG1653@2|Bacteria,1R5TB@1224|Proteobacteria,1RSBF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
MMD2_k127_851183_29	1121937.AUHJ01000007_gene1807	2.207e-47	183.0	2E62A@1|root,330RE@2|Bacteria,1QYUK@1224|Proteobacteria,1T3VD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
MMD2_k127_851183_42	1207058.L53_06300	8.079e-27	121.0	COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,43XXP@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	COG3474 Cytochrome c2	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0016020,GO:0044237,GO:0044464,GO:0071944	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
MMD2_k127_851183_46	1121405.dsmv_1236	3.29e-10	68.0	2EB0T@1|root,3351P@2|Bacteria,1NJAF@1224|Proteobacteria,431ZP@68525|delta/epsilon subdivisions,2WW83@28221|Deltaproteobacteria,2MNY6@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_851183_0	1033802.SSPSH_002596	0.0	1094.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Dehydrogenase E1 component	sucA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
MMD2_k127_851183_8	768671.ThimaDRAFT_2327	3.096e-148	482.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1WXGA@135613|Chromatiales	135613|Chromatiales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMD2_k127_851183_6	1318628.MARLIPOL_06564	2.088e-176	571.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,463YH@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iE2348C_1286.E2348C_4372,iJN746.PP_4187	Pyr_redox_2,Pyr_redox_dim
MMD2_k127_851183_31	1283300.ATXB01000002_gene3028	4.213e-42	166.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XF1A@135618|Methylococcales	135618|Methylococcales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
MMD2_k127_851183_24	1283300.ATXB01000002_gene3027	1.055e-61	218.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1XEQU@135618|Methylococcales	135618|Methylococcales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
MMD2_k127_851183_7	314278.NB231_11894	4.223e-164	522.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1WWB3@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
MMD2_k127_851183_40	1304275.C41B8_10970	2.315e-31	127.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Thioesterase	ybgC	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790	3.1.2.23	ko:K01075,ko:K07107	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_0747,iSDY_1059.SDY_0684	4HBT
MMD2_k127_851183_21	765912.Thimo_0571	4.444e-73	254.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1WWA0@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
MMD2_k127_851183_37	314278.NB231_15778	1.211e-37	150.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1WY2R@135613|Chromatiales	135613|Chromatiales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
MMD2_k127_851183_45	519989.ECTPHS_02189	1.727e-14	83.0	COG3064@1|root,COG3064@2|Bacteria,1R7WR@1224|Proteobacteria,1SZ86@1236|Gammaproteobacteria,1WWRY@135613|Chromatiales	135613|Chromatiales	M	TonB C terminal	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
MMD2_k127_851183_9	1283300.ATXB01000002_gene3020	1.972e-137	451.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XEH5@135618|Methylococcales	135618|Methylococcales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
MMD2_k127_851183_36	1049564.TevJSym_be00180	2.697e-38	149.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1J6Q8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
MMD2_k127_851183_34	396588.Tgr7_2227	2.215e-39	156.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1WW2G@135613|Chromatiales	135613|Chromatiales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
MMD2_k127_851183_16	1219375.CM002139_gene2581	2.318e-99	328.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1X4FR@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
MMD2_k127_851183_17	1123393.KB891316_gene1511	4.24e-99	331.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,1KS0G@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Queuosine biosynthesis protein QueC	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
MMD2_k127_851183_43	56110.Oscil6304_0111	9.518e-27	126.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
MMD2_k127_851183_5	886293.Sinac_1153	4.291e-185	610.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_851183_13	886293.Sinac_1154	3.051e-111	377.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_851183_33	279238.Saro_1650	2.981e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,1R6FG@1224|Proteobacteria,2U4WA@28211|Alphaproteobacteria,2KB8R@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_851183_22	235985.BBPN01000008_gene4023	1.821e-72	250.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,2NJ2F@228398|Streptacidiphilus	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMD2_k127_851183_27	187272.Mlg_1793	3.281e-49	183.0	COG4195@1|root,COG4195@2|Bacteria,1MZZB@1224|Proteobacteria,1SH88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Poly-gamma-glutamate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Gamma_PGA_hydro
MMD2_k127_851183_28	1125863.JAFN01000001_gene2385	4.21e-48	180.0	COG0494@1|root,COG0494@2|Bacteria,1MYSK@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.17	ko:K01518	ko00230,ko00240,map00230,map00240	-	R00184,R00969,R01232,R02805	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
MMD2_k127_851183_19	622637.KE124774_gene1697	9.684e-91	305.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,P22_AR_N,PriCT_1,Prim-Pol
MMD2_k127_851183_1	1123368.AUIS01000032_gene1395	7.899e-270	855.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMD2_k127_851183_38	1452718.JBOY01000002_gene468	4.298e-37	152.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	universal stress protein	ydaA	-	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
MMD2_k127_851183_44	86416.Clopa_1259	9.446e-22	102.0	COG2905@1|root,COG2905@2|Bacteria,1VW3X@1239|Firmicutes,24MYP@186801|Clostridia,36IUV@31979|Clostridiaceae	186801|Clostridia	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMD2_k127_851183_25	243231.GSU1159	4.014e-59	210.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42SWA@68525|delta/epsilon subdivisions,2WPE1@28221|Deltaproteobacteria,43W0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
MMD2_k127_851183_18	697282.Mettu_0390	5.516e-95	323.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,1S0QR@1236|Gammaproteobacteria,1XFU4@135618|Methylococcales	135618|Methylococcales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMD2_k127_851183_23	627192.SLG_20080	2.696e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,1R4GG@1224|Proteobacteria,2TV1Y@28211|Alphaproteobacteria,2KCNM@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMD2_k127_851183_10	627192.SLG_20070	8.656e-131	429.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VFM0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMD2_k127_851183_15	1211112.ALJC01000006_gene148	8.898e-107	361.0	COG2271@1|root,COG2271@2|Bacteria,1QWH9@1224|Proteobacteria,1T3YV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMD2_k127_851183_35	314275.MADE_1018500	1.69e-38	166.0	COG0810@1|root,COG0810@2|Bacteria,1RGHP@1224|Proteobacteria,1S54W@1236|Gammaproteobacteria,46ACR@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
MMD2_k127_851183_14	627192.SLG_20120	3.596e-110	360.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,2U189@28211|Alphaproteobacteria,2K4PZ@204457|Sphingomonadales	204457|Sphingomonadales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMD2_k127_869497_10	314278.NB231_05586	1.197e-48	182.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
MMD2_k127_869497_1	1123400.KB904780_gene1823	2.353e-174	577.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,45ZR5@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMD2_k127_869497_4	323261.Noc_2861	3.964e-116	392.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1WWB9@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
MMD2_k127_869497_7	247633.GP2143_10887	7.156e-102	344.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1J5FI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan polymerase that is essential for cell division	ftsW	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
MMD2_k127_869497_5	396588.Tgr7_0767	4.322e-116	393.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
MMD2_k127_869497_3	1085623.GNIT_2699	5.245e-123	415.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,465NF@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
MMD2_k127_869497_6	1415780.JPOG01000001_gene534	1.265e-106	362.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1X3IV@135614|Xanthomonadales	135614|Xanthomonadales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMD2_k127_869497_2	1123257.AUFV01000017_gene3754	1.402e-127	430.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1X488@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMD2_k127_869497_0	396588.Tgr7_0763	2.18e-183	592.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
MMD2_k127_869497_11	314278.NB231_05631	4.596e-13	80.0	COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SGSB@1236|Gammaproteobacteria,1WZ00@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
MMD2_k127_869497_8	1123256.KB907929_gene3335	7.367e-98	329.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1X2YP@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
MMD2_k127_869497_9	1335757.SPICUR_07680	6.345e-58	206.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1WYVR@135613|Chromatiales	135613|Chromatiales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
MMD2_k127_870239_13	1283300.ATXB01000001_gene2306	1.069e-28	115.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XEKU@135618|Methylococcales	135618|Methylococcales	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
MMD2_k127_870239_2	458817.Shal_2461	7.509e-174	569.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2NX@1236|Gammaproteobacteria,2Q91E@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
MMD2_k127_870239_10	1121937.AUHJ01000014_gene2676	2.191e-55	201.0	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,467GF@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
MMD2_k127_870239_14	1144343.PMI41_00873	5.748e-14	85.0	COG0510@1|root,COG0510@2|Bacteria,1MVBB@1224|Proteobacteria,2TT5Z@28211|Alphaproteobacteria,43J57@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Choline kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
MMD2_k127_870239_4	648757.Rvan_0900	5.168e-125	409.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,3N6GY@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	MA20_25935	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMD2_k127_870239_6	1121918.ARWE01000001_gene49	1.876e-110	363.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,42NB1@68525|delta/epsilon subdivisions,2WM1K@28221|Deltaproteobacteria,43U87@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
MMD2_k127_870239_8	234267.Acid_5600	1.774e-94	321.0	COG3391@1|root,COG3391@2|Bacteria,3Y48Y@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_870239_3	1121033.AUCF01000026_gene2977	3.993e-141	452.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,2JWA9@204441|Rhodospirillales	204441|Rhodospirillales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
MMD2_k127_870239_12	62928.azo2523	4.908e-46	170.0	COG3384@1|root,COG3384@2|Bacteria,1RIBC@1224|Proteobacteria,2VSU2@28216|Betaproteobacteria,2KYSN@206389|Rhodocyclales	206389|Rhodocyclales	S	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	-	-	1.13.11.8	ko:K04100	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA
MMD2_k127_870239_11	159087.Daro_2740	7.177e-53	191.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,2KW50@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
MMD2_k127_870239_7	584708.Apau_0766	6.898e-100	334.0	COG0588@1|root,COG0588@2|Bacteria,3TA2G@508458|Synergistetes	508458|Synergistetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
MMD2_k127_870239_9	1267534.KB906759_gene1718	6.251e-88	305.0	COG3483@1|root,COG3483@2|Bacteria,3Y9FJ@57723|Acidobacteria,2JP7W@204432|Acidobacteriia	204432|Acidobacteriia	E	Tryptophan 2,3-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_dioxygenase
MMD2_k127_870239_5	187272.Mlg_0334	1.977e-124	408.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,1WW2P@135613|Chromatiales	135613|Chromatiales	D	Reduces the stability of FtsZ polymers in the presence of ATP	zapE	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
MMD2_k127_870239_0	472759.Nhal_2509	1.738e-264	834.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1WW8N@135613|Chromatiales	135613|Chromatiales	I	Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMD2_k127_870239_1	322710.Avin_16430	1.693e-218	692.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	etfD	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8
MMD2_k127_876015_3	1238182.C882_1028	7.752e-42	160.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2UD5T@28211|Alphaproteobacteria,2JX90@204441|Rhodospirillales	204441|Rhodospirillales	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_876015_6	519989.ECTPHS_08106	8.33e-33	134.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
MMD2_k127_876015_7	1238182.C882_0029	3.76e-20	96.0	COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,2UCCK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_876015_2	1226994.AMZB01000120_gene3356	6.692e-53	198.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1YF68@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Universal stress protein family	ydaA	-	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
MMD2_k127_876015_5	1121918.ARWE01000001_gene103	1.34e-34	138.0	COG0517@1|root,COG0517@2|Bacteria,1QQRM@1224|Proteobacteria,42TVT@68525|delta/epsilon subdivisions,2WQBQ@28221|Deltaproteobacteria,43VA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMD2_k127_876015_4	1163409.UUA_13145	4.224e-36	146.0	COG3439@1|root,COG3439@2|Bacteria,1RHJQ@1224|Proteobacteria,1S5ZG@1236|Gammaproteobacteria,1XB3Y@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
MMD2_k127_876015_8	243160.BMAA2024	2.981e-16	88.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,2VY9Z@28216|Betaproteobacteria,1K93R@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM zinc finger DksA TraR C4-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
MMD2_k127_876015_0	1121374.KB891586_gene2542	1.191e-232	752.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
MMD2_k127_876015_1	1123368.AUIS01000019_gene1213	3.957e-59	211.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales	225057|Acidithiobacillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMD2_k127_876015_9	420324.KI911999_gene8065	4.754e-05	45.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,1JQQ0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM Glucose Sorbosone dehydrogenase	yliI	-	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH
MMD2_k127_885080_2	1280950.HJO_14382	1.662e-51	192.0	COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U69N@28211|Alphaproteobacteria,43XNX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,PCMT
MMD2_k127_885080_5	1122603.ATVI01000006_gene524	5.606e-05	56.0	COG2133@1|root,COG3386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,1R2KP@1224|Proteobacteria,1T5SI@1236|Gammaproteobacteria,1XB12@135614|Xanthomonadales	2|Bacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
MMD2_k127_885080_0	1122604.JONR01000007_gene2934	6.95e-172	563.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,1MY07@1224|Proteobacteria	1224|Proteobacteria	O	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_885080_4	1384054.N790_14190	7.636e-18	90.0	COG5455@1|root,COG5455@2|Bacteria,1RJVB@1224|Proteobacteria	1224|Proteobacteria	D	Nickel/cobalt transporter regulator	-	-	-	-	-	-	-	-	-	-	-	-	RcnB
MMD2_k127_885080_3	1454004.AW11_01909	5.906e-26	123.0	2DFFT@1|root,2ZRPJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_885080_1	234267.Acid_2106	2.612e-158	520.0	COG2272@1|root,COG2272@2|Bacteria,3Y3ME@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
MMD2_k127_885080_6	406818.XBJ1_1232	0.0001006	53.0	2DTB2@1|root,33JHD@2|Bacteria,1NNE4@1224|Proteobacteria,1SHWV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_895170_12	627192.SLG_31400	1.055e-89	302.0	COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_895170_7	627192.SLG_31390	1.498e-123	416.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
MMD2_k127_895170_13	883080.HMPREF9697_01644	2.057e-81	282.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2TREP@28211|Alphaproteobacteria,3JWVC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	dehH	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMD2_k127_895170_4	765420.OSCT_3161	8.771e-155	497.0	COG0451@1|root,COG0451@2|Bacteria,2G5PB@200795|Chloroflexi,37576@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMD2_k127_895170_14	1188256.BASI01000003_gene2898	1.602e-71	255.0	2DBS0@1|root,2ZANT@2|Bacteria,1R8Y3@1224|Proteobacteria,2U146@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_895170_6	1123257.AUFV01000005_gene1303	1.887e-136	449.0	COG1262@1|root,COG1262@2|Bacteria,1R59H@1224|Proteobacteria	1224|Proteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
MMD2_k127_895170_5	1123256.KB907931_gene2742	8.162e-153	514.0	2C4HX@1|root,2Z9XP@2|Bacteria,1MY22@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_895170_11	397945.Aave_0064	1.244e-111	377.0	COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria,4AD46@80864|Comamonadaceae	28216|Betaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
MMD2_k127_895170_10	1122604.JONR01000039_gene3778	1.135e-112	371.0	COG2521@1|root,COG2521@2|Bacteria,1Q0VI@1224|Proteobacteria,1S18J@1236|Gammaproteobacteria,1XC99@135614|Xanthomonadales	135614|Xanthomonadales	S	Methyl-transferase	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_30
MMD2_k127_895170_15	797209.ZOD2009_20687	4.487e-55	221.0	COG1501@1|root,arCOG03663@2157|Archaea,2XV49@28890|Euryarchaeota,23V0G@183963|Halobacteria	183963|Halobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
MMD2_k127_895170_1	1122603.ATVI01000011_gene2004	3.191e-217	691.0	COG4178@1|root,COG4178@2|Bacteria,1MW09@1224|Proteobacteria,1RPQA@1236|Gammaproteobacteria,1XAD4@135614|Xanthomonadales	135614|Xanthomonadales	S	SbmA/BacA-like family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane_2
MMD2_k127_895170_8	395965.Msil_0405	1.153e-121	407.0	COG3387@1|root,COG3387@2|Bacteria,1R65A@1224|Proteobacteria,2U210@28211|Alphaproteobacteria,3NA5M@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 15	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
MMD2_k127_895170_2	543728.Vapar_5524	5.068e-216	679.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,2VI7H@28216|Betaproteobacteria,4AD7E@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
MMD2_k127_895170_0	1122603.ATVI01000011_gene2001	6.534e-315	978.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1X4AX@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glycosyl hydrolase 3 family	-	-	-	-	-	-	-	-	-	-	-	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
MMD2_k127_895170_9	398525.KB900701_gene2369	1.253e-113	386.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
MMD2_k127_895170_17	1209072.ALBT01000032_gene2122	1.931e-07	64.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_895170_16	1209072.ALBT01000032_gene2124	2.592e-18	100.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_895170_3	395493.BegalDRAFT_1942	4.042e-207	666.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC-type oligopeptide transport system, periplasmic component	yejA	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
MMD2_k127_898621_4	1283300.ATXB01000001_gene1141	1.185e-122	405.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1XE2N@135618|Methylococcales	135618|Methylococcales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
MMD2_k127_898621_11	426355.Mrad2831_1792	1.376e-15	79.0	COG2337@1|root,COG2337@2|Bacteria,1MZAV@1224|Proteobacteria,2UD15@28211|Alphaproteobacteria,1JVYU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
MMD2_k127_898621_14	1120956.JHZK01000003_gene248	1.543e-09	61.0	2ERYD@1|root,33JHI@2|Bacteria,1NATI@1224|Proteobacteria,2UJAA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein  of unknown function (DUF3018)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3018
MMD2_k127_898621_0	1122604.JONR01000017_gene4318	7.147e-294	911.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1X43R@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
MMD2_k127_898621_2	396588.Tgr7_3303	2.268e-168	540.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1WWG8@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
MMD2_k127_898621_1	666685.R2APBS1_0675	2.521e-187	597.0	COG1032@1|root,COG1032@2|Bacteria,1RCWX@1224|Proteobacteria,1SYF2@1236|Gammaproteobacteria,1X5WI@135614|Xanthomonadales	135614|Xanthomonadales	C	Mg-protoporphyrin IX monomethyl ester oxidative cyclase	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
MMD2_k127_898621_3	479434.Sthe_3412	7.731e-162	525.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD2_k127_898621_8	666685.R2APBS1_0674	2.774e-89	312.0	2EIP2@1|root,33CEF@2|Bacteria,1QSUQ@1224|Proteobacteria,1RWF0@1236|Gammaproteobacteria,1X3GT@135614|Xanthomonadales	135614|Xanthomonadales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
MMD2_k127_898621_12	388467.A19Y_0195	1.814e-15	86.0	COG0275@1|root,COG0275@2|Bacteria	2|Bacteria	J	rRNA processing	noeI	-	-	ko:K21402	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_21,rRNA_methylase
MMD2_k127_898621_6	1144325.PMI22_00139	1.417e-99	352.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMD2_k127_898621_10	56107.Cylst_0436	2.261e-33	143.0	COG1216@1|root,COG1216@2|Bacteria,1G2ZC@1117|Cyanobacteria,1HKUT@1161|Nostocales	1117|Cyanobacteria	S	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD2_k127_898621_13	2002.JOEQ01000010_gene6290	1.918e-13	83.0	COG0615@1|root,COG0615@2|Bacteria,2IC88@201174|Actinobacteria,4EH6N@85012|Streptosporangiales	201174|Actinobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
MMD2_k127_898621_5	1163409.UUA_15238	4.267e-120	413.0	COG0438@1|root,COG0438@2|Bacteria,1PDQY@1224|Proteobacteria,1SE53@1236|Gammaproteobacteria,1X59A@135614|Xanthomonadales	135614|Xanthomonadales	M	Hexosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMD2_k127_898621_9	1163409.UUA_15283	1.565e-69	248.0	COG0467@1|root,COG0467@2|Bacteria,1PC3B@1224|Proteobacteria,1SWVT@1236|Gammaproteobacteria,1X5JX@135614|Xanthomonadales	135614|Xanthomonadales	T	Serine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_898621_7	187272.Mlg_2321	7.96e-92	322.0	COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,1RQDM@1236|Gammaproteobacteria,1X2CT@135613|Chromatiales	135613|Chromatiales	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
MMD2_k127_908665_4	472759.Nhal_3857	4.151e-243	764.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales	135613|Chromatiales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
MMD2_k127_908665_29	76114.ebA4334	5.048e-40	153.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,2KWKI@206389|Rhodocyclales	206389|Rhodocyclales	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
MMD2_k127_908665_28	1123073.KB899241_gene3414	1.363e-43	172.0	COG1073@1|root,COG1073@2|Bacteria,1R1F2@1224|Proteobacteria	1224|Proteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMD2_k127_908665_27	522306.CAP2UW1_3877	1.168e-51	205.0	COG4249@1|root,COG4249@2|Bacteria,1QU7W@1224|Proteobacteria,2VITZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase C13 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C13
MMD2_k127_908665_1	765912.Thimo_2109	1.258e-318	998.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales	135613|Chromatiales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
MMD2_k127_908665_12	1429916.X566_23305	6.347e-111	365.0	COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,2U1U3@28211|Alphaproteobacteria,3JUR6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD2_k127_908665_24	272630.MexAM1_META1p3770	2.275e-57	206.0	COG0212@1|root,COG0212@2|Bacteria,1RAZI@1224|Proteobacteria,2U6UH@28211|Alphaproteobacteria,1JU5Y@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	5-FTHF_cyc-lig
MMD2_k127_908665_26	570967.JMLV01000001_gene2938	1.601e-54	203.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,2JRX8@204441|Rhodospirillales	204441|Rhodospirillales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
MMD2_k127_908665_35	314287.GB2207_07527	1.787e-16	87.0	COG3637@1|root,COG3637@2|Bacteria,1N2TS@1224|Proteobacteria,1SBJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
MMD2_k127_908665_19	1049564.TevJSym_ao00490	1.07e-82	288.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1SZ82@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Protein of unknown function, DUF484	-	-	-	-	-	-	-	-	-	-	-	-	DUF484,GGDEF
MMD2_k127_908665_2	1121948.AUAC01000006_gene651	6.824e-287	894.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,43WW1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN
MMD2_k127_908665_8	394221.Mmar10_0401	1.701e-178	564.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2TS3X@28211|Alphaproteobacteria,43WU8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdF	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
MMD2_k127_908665_31	640512.BC1003_4482	2.372e-36	151.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2VT72@28216|Betaproteobacteria,1K7PJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
MMD2_k127_908665_30	93220.LV28_08690	2.909e-37	145.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2VSDD@28216|Betaproteobacteria,1K8TY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
MMD2_k127_908665_34	313624.NSP_36860	7.533e-28	130.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1HKRU@1161|Nostocales	1117|Cyanobacteria	S	PFAM Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
MMD2_k127_908665_7	234267.Acid_5827	1.891e-206	672.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
MMD2_k127_908665_10	1340493.JNIF01000003_gene1475	1.197e-117	407.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMD2_k127_908665_37	861299.J421_1961	1.115e-08	69.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
MMD2_k127_908665_0	686340.Metal_3778	0.0	1282.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNST@1236|Gammaproteobacteria,1XGZ1@135618|Methylococcales	135618|Methylococcales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
MMD2_k127_908665_22	158500.BV97_05631	1.057e-68	257.0	COG0845@1|root,COG0845@2|Bacteria,1R9MI@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
MMD2_k127_908665_25	158500.BV97_05630	3.981e-55	213.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VEVS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD2_k127_908665_17	158500.BV97_05629	4.858e-89	311.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2TWY4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07644,ko:K07649	ko02020,map02020	M00452,M00457,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
MMD2_k127_908665_38	641149.HMPREF9016_01212	4.589e-06	57.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,2VXX3@28216|Betaproteobacteria,2KS5G@206351|Neisseriales	206351|Neisseriales	C	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	ABM
MMD2_k127_908665_15	1340493.JNIF01000003_gene3965	1.311e-100	342.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMD2_k127_908665_16	402881.Plav_0822	1.806e-93	316.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2TTFG@28211|Alphaproteobacteria,1JP6D@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD2_k127_908665_20	1218074.BAXZ01000019_gene3873	1.047e-73	258.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,2W2Z1@28216|Betaproteobacteria,1KF3H@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMD2_k127_908665_39	1380356.JNIK01000013_gene3980	0.0003264	50.0	2EQU1@1|root,33IDR@2|Bacteria,2I5UM@201174|Actinobacteria,4EWVD@85013|Frankiales	201174|Actinobacteria	Q	Ring hydroxylating beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD2_k127_908665_33	1082933.MEA186_33654	5.915e-28	117.0	COG3254@1|root,COG3254@2|Bacteria,1RIRS@1224|Proteobacteria,2UAT0@28211|Alphaproteobacteria,43QBK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	rhamnose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	ABM
MMD2_k127_908665_23	1230476.C207_05492	3.195e-63	235.0	COG3391@1|root,COG3391@2|Bacteria,1MXRF@1224|Proteobacteria,2U1E9@28211|Alphaproteobacteria,3JTTY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD2_k127_908665_18	1234364.AMSF01000005_gene741	1.682e-86	298.0	2DIWG@1|root,3049N@2|Bacteria,1R88E@1224|Proteobacteria,1T49R@1236|Gammaproteobacteria,1X4QT@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
MMD2_k127_908665_11	504472.Slin_4173	4.013e-117	391.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47M3Z@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMD2_k127_908665_14	1123368.AUIS01000028_gene1327	2.671e-103	342.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	(ABC) transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_908665_3	1085623.GNIT_2958	6.459e-283	890.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria,465XQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD2_k127_908665_9	1085623.GNIT_2957	3.689e-128	421.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria,4665P@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
MMD2_k127_908665_6	204773.HEAR0614	2.417e-230	726.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VH8Z@28216|Betaproteobacteria,4739Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt1	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMD2_k127_908665_36	485913.Krac_4987	1.501e-14	83.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
MMD2_k127_908665_21	234267.Acid_3750	4.565e-73	259.0	COG1131@1|root,COG1131@2|Bacteria,3Y50U@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD2_k127_908665_32	639030.JHVA01000001_gene2678	2.655e-32	130.0	COG1725@1|root,COG1725@2|Bacteria,3Y5VN@57723|Acidobacteria,2JK5T@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
MMD2_k127_908665_13	123899.JPQP01000002_gene883	2.79e-110	364.0	COG3555@1|root,COG3555@2|Bacteria,1MW3M@1224|Proteobacteria,2VIET@28216|Betaproteobacteria,3T3AB@506|Alcaligenaceae	28216|Betaproteobacteria	O	Aspartyl asparaginyl beta-hydroxylase and related dioxygenases	lpxO1	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
MMD2_k127_908665_5	395495.Lcho_0082	1.124e-232	724.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VI7S@28216|Betaproteobacteria,1KJS1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Aminotransferase class I and II	alaC	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD2_k127_93629_1	1120956.JHZK01000010_gene2755	1.458e-79	279.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMD2_k127_93629_3	555793.WSK_2986	4.405e-77	275.0	COG0457@1|root,COG0457@2|Bacteria,1RBEJ@1224|Proteobacteria,2U6X2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_93629_2	1042209.HK44_006025	9.742e-78	271.0	COG4874@1|root,COG4874@2|Bacteria,1N05R@1224|Proteobacteria,1S34T@1236|Gammaproteobacteria,1YN12@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
MMD2_k127_93629_5	1265313.HRUBRA_02744	1.987e-62	226.0	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,1J671@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
MMD2_k127_93629_6	1385515.N791_03520	4.977e-20	94.0	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria,1X82S@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_93629_7	1085623.GNIT_1964	7.689e-10	66.0	COG5126@1|root,COG5126@2|Bacteria,1N188@1224|Proteobacteria,1SAIA@1236|Gammaproteobacteria,467YK@72275|Alteromonadaceae	1236|Gammaproteobacteria	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_1,EF-hand_5,EF-hand_6,EF-hand_7,EF-hand_8
MMD2_k127_93629_4	87626.PTD2_02306	2.822e-71	263.0	COG2807@1|root,COG2807@2|Bacteria,1NXQ2@1224|Proteobacteria,1RXXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_93629_8	580332.Slit_1229	0.0005511	53.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	2.7.11.1	ko:K12132,ko:K20543	-	-	-	-	ko00000,ko01000,ko01001,ko02000	1.B.55.3	-	-	AAA_16,NfrA_C,Pkinase,TPR_10,TPR_12,TPR_14,TPR_16,TPR_19,TPR_8
MMD2_k127_93629_0	399739.Pmen_1002	3.723e-222	711.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1YD67@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
MMD2_k127_964054_51	400682.PAC_15705797	4.178e-17	80.0	COG0050@1|root,KOG0460@2759|Eukaryota,38BHM@33154|Opisthokonta,3BE5J@33208|Metazoa	33208|Metazoa	J	translation elongation factor activity	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMD2_k127_964054_29	1260251.SPISAL_07480	7.769e-52	184.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1WYRW@135613|Chromatiales	135613|Chromatiales	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
MMD2_k127_964054_16	713586.KB900536_gene1170	3.983e-87	293.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1WVZS@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
MMD2_k127_964054_20	1121943.KB900007_gene1965	4.727e-72	251.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XH61@135619|Oceanospirillales	135619|Oceanospirillales	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
MMD2_k127_964054_46	640081.Dsui_0357	3.655e-24	113.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,2KWRX@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
MMD2_k127_964054_8	1415779.JOMH01000001_gene362	1.916e-130	423.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1X3GB@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
MMD2_k127_964054_37	1288494.EBAPG3_29840	5.076e-42	156.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2VSGE@28216|Betaproteobacteria,373AS@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
MMD2_k127_964054_40	1168067.JAGP01000001_gene261	9.459e-39	147.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,460UB@72273|Thiotrichales	72273|Thiotrichales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
MMD2_k127_964054_14	555778.Hneap_0329	7.319e-96	318.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1WVYC@135613|Chromatiales	135613|Chromatiales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
MMD2_k127_964054_22	377629.TERTU_0915	1.278e-68	236.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,2PNFE@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Ribosomal protein L16p/L10e	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
MMD2_k127_964054_55	1382303.JPOM01000001_gene1849	1.207e-11	69.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2UF59@28211|Alphaproteobacteria,2KH8N@204458|Caulobacterales	204458|Caulobacterales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
MMD2_k127_964054_44	1089547.KB913013_gene2127	3.233e-28	116.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,47R6N@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
MMD2_k127_964054_26	1163407.UU7_10835	2.75e-60	209.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1X6K2@135614|Xanthomonadales	135614|Xanthomonadales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
MMD2_k127_964054_39	1249627.D779_3561	9.032e-39	153.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1WYKG@135613|Chromatiales	135613|Chromatiales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
MMD2_k127_964054_18	1385517.N800_05420	8.236e-80	271.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1X3RF@135614|Xanthomonadales	135614|Xanthomonadales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
MMD2_k127_964054_42	519989.ECTPHS_13123	5.728e-34	132.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1WYNJ@135613|Chromatiales	135613|Chromatiales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
MMD2_k127_964054_34	713586.KB900536_gene1156	6.363e-47	173.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1WXYT@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
MMD2_k127_964054_23	396588.Tgr7_2309	7.452e-65	227.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1WXV2@135613|Chromatiales	135613|Chromatiales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
MMD2_k127_964054_21	1122604.JONR01000006_gene2673	6.287e-71	243.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1X5KF@135614|Xanthomonadales	135614|Xanthomonadales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
MMD2_k127_964054_50	1123399.AQVE01000003_gene2026	2.828e-17	84.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,4617P@72273|Thiotrichales	72273|Thiotrichales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
MMD2_k127_964054_36	349124.Hhal_0839	3.854e-43	162.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1WYR5@135613|Chromatiales	135613|Chromatiales	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
MMD2_k127_964054_1	395493.BegalDRAFT_2604	1.163e-198	627.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales	72273|Thiotrichales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
MMD2_k127_964054_54	519989.ECTPHS_13163	4.72e-13	69.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,1WZNA@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
MMD2_k127_964054_32	1123354.AUDR01000018_gene1230	2.964e-49	177.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,1KRQ5@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
MMD2_k127_964054_25	395493.BegalDRAFT_2601	2.826e-61	213.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,460IQ@72273|Thiotrichales	72273|Thiotrichales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
MMD2_k127_964054_17	930169.B5T_03771	2.227e-86	289.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1XI4I@135619|Oceanospirillales	135619|Oceanospirillales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
MMD2_k127_964054_5	553385.JEMF01000006_gene3402	1.44e-144	465.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XH9U@135619|Oceanospirillales	135619|Oceanospirillales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
MMD2_k127_964054_30	1137799.GZ78_25590	2.905e-50	181.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1XJJW@135619|Oceanospirillales	135619|Oceanospirillales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
MMD2_k127_964054_48	1144275.COCOR_07919	7.485e-22	104.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
MMD2_k127_964054_24	1218075.BAYA01000003_gene804	2.624e-63	232.0	COG0583@1|root,COG0583@2|Bacteria,1PEF2@1224|Proteobacteria,2VQ7W@28216|Betaproteobacteria,1K469@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	nodD	-	-	ko:K14657	-	M00664	-	-	ko00000,ko00002,ko03000	-	-	-	HTH_1,LysR_substrate
MMD2_k127_964054_57	627192.SLG_09870	1.474e-07	61.0	2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_964054_52	450851.PHZ_c2572	4.722e-17	93.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_964054_35	1528106.JRJE01000008_gene1527	3.224e-45	177.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,2JWDZ@204441|Rhodospirillales	204441|Rhodospirillales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_964054_45	1349785.BAUG01000022_gene1419	1.838e-25	124.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1HYC1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD2_k127_964054_0	305900.GV64_14145	0.0	1086.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1XH5W@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMD2_k127_964054_19	349124.Hhal_0219	4.563e-78	270.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1WXIR@135613|Chromatiales	135613|Chromatiales	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
MMD2_k127_964054_15	627192.SLG_08140	2.444e-93	331.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,2U1WU@28211|Alphaproteobacteria,2K1HS@204457|Sphingomonadales	204457|Sphingomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
MMD2_k127_964054_28	589865.DaAHT2_1335	4.477e-55	203.0	COG0524@1|root,COG0524@2|Bacteria,1Q1GY@1224|Proteobacteria,42REZ@68525|delta/epsilon subdivisions,2WNHE@28221|Deltaproteobacteria,2MND3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM PfkB	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMD2_k127_964054_13	69395.JQLZ01000004_gene599	3.545e-105	351.0	COG1609@1|root,COG1609@2|Bacteria,1MW7E@1224|Proteobacteria,2TVGC@28211|Alphaproteobacteria,2KHSG@204458|Caulobacterales	204458|Caulobacterales	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
MMD2_k127_964054_10	1134474.O59_003250	6.595e-126	415.0	COG0738@1|root,COG0738@2|Bacteria,1Q64C@1224|Proteobacteria,1RQG1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD2_k127_964054_3	1126627.BAWE01000004_gene1739	2.713e-180	584.0	COG3509@1|root,COG3509@2|Bacteria,1QW8F@1224|Proteobacteria,2TWSR@28211|Alphaproteobacteria,3JWT6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.1.1.102	ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	Tannase
MMD2_k127_964054_7	1292034.OR37_02324	2.334e-134	437.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2U0DE@28211|Alphaproteobacteria,2KH92@204458|Caulobacterales	204458|Caulobacterales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMD2_k127_964054_2	365044.Pnap_0232	4.224e-198	628.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria	1224|Proteobacteria	G	'PFAM Alpha amylase, catalytic	-	GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
MMD2_k127_964054_53	405948.SACE_2796	1.623e-13	79.0	COG1846@1|root,COG1846@2|Bacteria,2IMTS@201174|Actinobacteria,4E5MQ@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMD2_k127_964054_60	67352.JODS01000012_gene4389	0.0003327	52.0	COG0515@1|root,COG0515@2|Bacteria,2GMRN@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like,Pkinase
MMD2_k127_964054_43	349124.Hhal_2346	7.61e-29	124.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMD2_k127_964054_12	1123253.AUBD01000005_gene206	2.017e-118	396.0	COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,1X3Z6@135614|Xanthomonadales	135614|Xanthomonadales	E	Splits dipeptides with a prolyl residue in the C- terminal position	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMD2_k127_964054_33	1379270.AUXF01000001_gene2605	2.747e-47	189.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_964054_58	1265490.JHVY01000030_gene4491	5.358e-07	58.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1S67S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD2_k127_964054_6	686340.Metal_3811	7.624e-135	443.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XDR0@135618|Methylococcales	135618|Methylococcales	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
MMD2_k127_964054_38	1254432.SCE1572_37410	2.455e-41	156.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_37410|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_964054_11	97096.XP_007790920.1	2.608e-121	410.0	COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes	4751|Fungi	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMD2_k127_964054_41	1120972.AUMH01000006_gene1809	2.16e-38	165.0	COG0657@1|root,COG0657@2|Bacteria,1UWRG@1239|Firmicutes,4I9QW@91061|Bacilli,27AB6@186823|Alicyclobacillaceae	91061|Bacilli	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMD2_k127_964054_47	926566.Terro_1070	3.174e-23	106.0	COG1661@1|root,COG1661@2|Bacteria,3Y4JP@57723|Acidobacteria,2JJAA@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
MMD2_k127_964054_27	215803.DB30_5827	1.405e-55	207.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,430ZU@68525|delta/epsilon subdivisions,2WWJB@28221|Deltaproteobacteria,2YV8T@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMD2_k127_964054_49	1260251.SPISAL_02000	7.915e-18	85.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,1WWVB@135613|Chromatiales	135613|Chromatiales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMD2_k127_998704_0	543728.Vapar_0124	2.858e-196	624.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2VIK2@28216|Betaproteobacteria,4ACVQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMD2_k127_998704_9	1415780.JPOG01000001_gene63	2.017e-53	195.0	COG3791@1|root,COG3791@2|Bacteria,1MZTR@1224|Proteobacteria,1S5QB@1236|Gammaproteobacteria,1X8A6@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_998704_2	1385517.N800_12050	1.166e-185	595.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1RMF0@1236|Gammaproteobacteria,1X3W2@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Major facilitator superfamily	yhjE	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMD2_k127_998704_5	627192.SLG_31140	1.014e-162	524.0	COG1113@1|root,COG1113@2|Bacteria,1MUPS@1224|Proteobacteria,2U0PN@28211|Alphaproteobacteria,2KD49@204457|Sphingomonadales	204457|Sphingomonadales	E	Amino acid permease	-	-	-	ko:K11735	-	-	-	-	ko00000,ko02000	2.A.3.1.4,2.A.3.1.5	-	-	AA_permease
MMD2_k127_998704_4	479434.Sthe_3255	7.108e-168	545.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	200795|Chloroflexi	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMD2_k127_998704_1	1340493.JNIF01000003_gene1440	1.05e-188	611.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
MMD2_k127_998704_13	1229204.AMYY01000023_gene2273	1.009e-07	62.0	2EIJE@1|root,33CAQ@2|Bacteria,1NH29@1224|Proteobacteria	1224|Proteobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_998704_10	1479238.JQMZ01000001_gene1013	2.464e-37	147.0	COG1595@1|root,COG1595@2|Bacteria,1RD9G@1224|Proteobacteria,2U92K@28211|Alphaproteobacteria,43Y7E@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
MMD2_k127_998704_12	1123228.AUIH01000012_gene96	5.74e-26	115.0	COG0398@1|root,COG0398@2|Bacteria,1P9BB@1224|Proteobacteria,1SUJE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMD2_k127_998704_8	1283299.AUKG01000003_gene531	3.35e-81	283.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4CQGN@84995|Rubrobacteria	84995|Rubrobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
MMD2_k127_998704_3	861299.J421_1107	1.298e-170	547.0	COG3391@1|root,COG3391@2|Bacteria,1ZSNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD2_k127_998704_7	864051.BurJ1DRAFT_2776	3.562e-115	391.0	COG2010@1|root,COG2010@2|Bacteria,1R1VN@1224|Proteobacteria,2WI66@28216|Betaproteobacteria,1KN79@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
MMD2_k127_998704_6	1396418.BATQ01000125_gene5116	1.035e-119	413.0	COG2091@1|root,COG2091@2|Bacteria,46VE0@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
MMD2_k127_998704_11	1396418.BATQ01000125_gene5116	1.483e-26	116.0	COG2091@1|root,COG2091@2|Bacteria,46VE0@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
## 3806 queries scanned
## Total time (seconds): 269.4226710796356
## Rate: 14.13 q/s