## Fri Nov 15 23:39:33 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin16/MMS_1_bin.5.fa -m mmseqs --itype genome -o MMS_1_bin.5 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/MMS_1_bin.5 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
MMS1_k127_1070097_1	589924.Ferp_0216	4.198e-19	89.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,245UG@183980|Archaeoglobi	183980|Archaeoglobi	O	AAA family ATPase, CDC48 subfamily	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
MMS1_k127_1070097_2	368408.Tpen_0422	4.699e-19	91.0	COG2125@1|root,arCOG01946@2157|Archaea,2XPW1@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
MMS1_k127_1070097_0	647113.Metok_0259	4.054e-109	365.0	COG3276@1|root,arCOG01563@2157|Archaea,2XUKU@28890|Euryarchaeota,23QPD@183939|Methanococci	183939|Methanococci	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2g	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,eIF2_C
MMS1_k127_1070097_3	272557.APE_0124	4.089e-18	96.0	COG2404@1|root,arCOG00423@2157|Archaea,2XQ5M@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM DHHA1 domain	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	DHHA1
MMS1_k127_1107147_3	1365176.N186_04140	1.78e-83	287.0	COG0160@1|root,arCOG00915@2157|Archaea,2XPMC@28889|Crenarchaeota	28889|Crenarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS1_k127_1107147_0	589924.Ferp_1250	7.014e-290	926.0	COG1933@1|root,arCOG04447@2157|Archaea,2XU5S@28890|Euryarchaeota,246MU@183980|Archaeoglobi	183980|Archaeoglobi	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
MMS1_k127_1107147_2	387631.Asulf_01728	3.343e-90	316.0	COG1311@1|root,arCOG04455@2157|Archaea,2XSUG@28890|Euryarchaeota,245U4@183980|Archaeoglobi	183980|Archaeoglobi	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	-	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B,Metallophos
MMS1_k127_1107147_17	420247.Msm_0733	4.256e-11	66.0	COG2163@1|root,arCOG04167@2157|Archaea,2XYTF@28890|Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL14 family	rpl14e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02875	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,Ribosomal_L14e
MMS1_k127_1107147_8	1229909.NSED_01960	3.018e-42	161.0	COG1102@1|root,arCOG01037@2157|Archaea,41SKS@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
MMS1_k127_1107147_15	243232.MJ_0655	4.569e-13	73.0	COG2174@1|root,arCOG04168@2157|Archaea,2Y0IH@28890|Euryarchaeota,23R6M@183939|Methanococci	183939|Methanococci	J	Belongs to the eukaryotic ribosomal protein eL34 family	rpl34e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02915	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34e
MMS1_k127_1107147_13	323259.Mhun_2229	3.608e-19	94.0	COG2019@1|root,arCOG01039@2157|Archaea,2XVK7@28890|Euryarchaeota	28890|Euryarchaeota	F	Belongs to the archaeal adenylate kinase family	adkA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
MMS1_k127_1107147_1	391623.TERMP_02050	7.095e-193	616.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,242UA@183968|Thermococci	183968|Thermococci	O	Belongs to the TCP-1 chaperonin family	ths	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
MMS1_k127_1107147_9	224325.AF_0043	1.344e-40	165.0	COG0438@1|root,arCOG01403@2157|Archaea,2XVUJ@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_1107147_16	1006006.Mcup_0430	3.144e-11	78.0	COG1287@1|root,arCOG02044@2157|Archaea,2XQVE@28889|Crenarchaeota	28889|Crenarchaeota	M	Oligosaccharyl transferase, STT3 subunit	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
MMS1_k127_1107147_10	868131.MSWAN_0290	2.493e-39	160.0	COG0644@1|root,arCOG00570@2157|Archaea,2XUI9@28890|Euryarchaeota,23NUG@183925|Methanobacteria	183925|Methanobacteria	C	Lycopene cyclase protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
MMS1_k127_1107147_5	1237149.C900_04376	1.26e-71	258.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,47KPD@768503|Cytophagia	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
MMS1_k127_1107147_12	469378.Ccur_08920	3.715e-29	119.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4CWAM@84998|Coriobacteriia	84998|Coriobacteriia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
MMS1_k127_1107147_19	523841.HFX_0625	2.461e-05	49.0	COG1996@1|root,arCOG04341@2157|Archaea,2XZUD@28890|Euryarchaeota,23XRR@183963|Halobacteria	183963|Halobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoP	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	DNA_RNApol_7kD
MMS1_k127_1107147_18	273063.STK_16450	2.906e-10	65.0	arCOG07348@1|root,arCOG07348@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1107147_14	342949.PNA2_0520	2.204e-14	75.0	COG1997@1|root,arCOG04208@2157|Archaea,2XYWD@28890|Euryarchaeota,244K8@183968|Thermococci	183968|Thermococci	J	binds to the 23S rRNA	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
MMS1_k127_1107147_7	634498.mru_1352	2.869e-58	211.0	COG2123@1|root,arCOG01574@2157|Archaea,2XWTK@28890|Euryarchaeota,23NYE@183925|Methanobacteria	183925|Methanobacteria	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	-	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
MMS1_k127_1107147_4	1183377.Py04_1444	8.392e-77	264.0	COG0689@1|root,arCOG01575@2157|Archaea,2XVHI@28890|Euryarchaeota,242PZ@183968|Thermococci	183968|Thermococci	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
MMS1_k127_1107147_11	186497.PF1569	6.296e-34	138.0	COG1097@1|root,arCOG00678@2157|Archaea,2XWEN@28890|Euryarchaeota,242IU@183968|Thermococci	183968|Thermococci	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,KH_6
MMS1_k127_1107147_6	439481.Aboo_0184	5.048e-62	220.0	COG1500@1|root,arCOG04187@2157|Archaea,2XTNH@28890|Euryarchaeota,3F2JN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
MMS1_k127_1108176_0	523850.TON_1557	2.814e-92	318.0	COG0621@1|root,arCOG01358@2157|Archaea,2XSVB@28890|Euryarchaeota,243CJ@183968|Thermococci	183968|Thermococci	J	methylthiotransferase activity	-	-	2.8.4.5	ko:K15865	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
MMS1_k127_1116778_0	263820.PTO0139	1.405e-53	201.0	COG0531@1|root,arCOG03649@2157|Archaea,2Y0EG@28890|Euryarchaeota,241ZT@183967|Thermoplasmata	183967|Thermoplasmata	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
MMS1_k127_1119253_2	573063.Metin_0698	7.802e-36	143.0	COG0202@1|root,arCOG04241@2157|Archaea,2XTQB@28890|Euryarchaeota,23QJ9@183939|Methanococci	183939|Methanococci	K	SMART RNA polymerase, RpoA D Rpb3-type	rpoD	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_A_bac,RNA_pol_L
MMS1_k127_1119253_5	272844.PAB0062	1.341e-18	94.0	COG1514@1|root,arCOG01736@2157|Archaea,2XZ2M@28890|Euryarchaeota,242VR@183968|Thermococci	183968|Thermococci	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
MMS1_k127_1119253_3	406327.Mevan_1337	5.865e-25	107.0	COG0143@1|root,arCOG00810@2157|Archaea,2XTG5@28890|Euryarchaeota,23QAZ@183939|Methanococci	183939|Methanococci	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
MMS1_k127_1119253_7	291985.CCSI01000007_gene495	0.0002232	52.0	COG4960@1|root,COG4960@2|Bacteria,1PKF9@1224|Proteobacteria,2UZA6@28211|Alphaproteobacteria,2K8E9@204457|Sphingomonadales	204457|Sphingomonadales	OU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
MMS1_k127_1119253_4	1365176.N186_04890	2.233e-22	104.0	COG1813@1|root,arCOG01863@2157|Archaea,2XQXA@28889|Crenarchaeota	28889|Crenarchaeota	K	PFAM helix-turn-helix domain protein	-	-	-	ko:K03627	-	-	-	-	ko00000	-	-	-	HTH_3
MMS1_k127_1119253_0	673860.AciM339_0552	9.292e-103	344.0	COG0258@1|root,arCOG04050@2157|Archaea,2XTJD@28890|Euryarchaeota,3F2GZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
MMS1_k127_1119253_1	673860.AciM339_0159	1.611e-69	243.0	COG0017@1|root,arCOG00407@2157|Archaea,2XTZJ@28890|Euryarchaeota,3F37W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	class II (D K and N)	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS1_k127_1128839_2	273075.Ta0192m	0.0004688	46.0	COG0500@1|root,arCOG01793@2157|Archaea,2Y1JK@28890|Euryarchaeota,242DW@183967|Thermoplasmata	183967|Thermoplasmata	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS1_k127_1128839_0	877455.Metbo_0198	9.044e-59	218.0	COG1736@1|root,arCOG04112@2157|Archaea,2XSY5@28890|Euryarchaeota,23NUP@183925|Methanobacteria	183925|Methanobacteria	J	Diphthamide	-	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
MMS1_k127_1128839_1	926562.Oweho_3543	1.346e-54	196.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1HXIQ@117743|Flavobacteriia,2PAX6@246874|Cryomorphaceae	976|Bacteroidetes	I	NUDIX domain	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
MMS1_k127_1157209_0	368408.Tpen_1762	1.838e-37	158.0	COG1061@1|root,arCOG00874@2157|Archaea,2XQ1C@28889|Crenarchaeota	28889|Crenarchaeota	K	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
MMS1_k127_1162179_2	69014.TK1328	1.826e-39	154.0	COG2519@1|root,arCOG00978@2157|Archaea,2XTV7@28890|Euryarchaeota,2439X@183968|Thermococci	183968|Thermococci	J	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
MMS1_k127_1162179_0	1343739.PAP_05975	2.178e-151	504.0	COG0550@1|root,arCOG01527@2157|Archaea,2XU6T@28890|Euryarchaeota,242TJ@183968|Thermococci	183968|Thermococci	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Topoisom_bac,Toprim,zf-C4_Topoisom
MMS1_k127_1162179_4	1487923.DP73_03080	6.49e-11	67.0	COG2510@1|root,COG2510@2|Bacteria,1VFXX@1239|Firmicutes,24NK9@186801|Clostridia,262YK@186807|Peptococcaceae	186801|Clostridia	S	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS1_k127_1162179_5	326427.Cagg_0826	1.253e-05	53.0	COG2076@1|root,COG2076@2|Bacteria,2G94V@200795|Chloroflexi,377JZ@32061|Chloroflexia	32061|Chloroflexia	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS1_k127_1162179_1	273116.14324833	7.135e-87	299.0	COG1215@1|root,arCOG01389@2157|Archaea,2Y7AD@28890|Euryarchaeota,24212@183967|Thermoplasmata	183967|Thermoplasmata	M	Glycosyl transferase family 21	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_21
MMS1_k127_1162179_3	490899.DKAM_0677	6.287e-36	149.0	COG0472@1|root,arCOG03199@2157|Archaea,2XPXP@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.15	ko:K01001	ko00510,ko01100,map00510,map01100	M00055	R05969	RC00002	ko00000,ko00001,ko00002,ko01000,ko01003	-	-	-	Glycos_transf_4
MMS1_k127_1165298_0	1459636.NTE_03216	2.722e-198	644.0	COG0525@1|root,arCOG00808@2157|Archaea,41SBK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Anticodon-binding domain of tRNA	-	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
MMS1_k127_121881_0	1227488.C477_10288	7.081e-59	215.0	COG3387@1|root,arCOG03286@2157|Archaea,2XUKJ@28890|Euryarchaeota,23SKS@183963|Halobacteria	183963|Halobacteria	G	COG3387 Glucoamylase and related glycosyl hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
MMS1_k127_1268819_0	693661.Arcve_1359	1.662e-05	58.0	COG3291@1|root,COG3979@1|root,arCOG02499@1|root,arCOG02552@1|root,arCOG03439@1|root,arCOG02499@2157|Archaea,arCOG02552@2157|Archaea,arCOG03439@2157|Archaea,arCOG03504@2157|Archaea,arCOG07581@2157|Archaea,2XXWR@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM periplasmic copper-binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
MMS1_k127_1297111_2	263820.PTO0099	7.535e-08	67.0	arCOG06052@1|root,arCOG06052@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1297111_0	931626.Awo_c14850	2.036e-92	316.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,25VEF@186806|Eubacteriaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMS1_k127_1297111_1	309801.trd_0377	9.53e-09	60.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi,27YGN@189775|Thermomicrobia	189775|Thermomicrobia	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMS1_k127_1299514_5	1120950.KB892750_gene6911	1.198e-21	100.0	COG0703@1|root,COG0703@2|Bacteria,2IHXC@201174|Actinobacteria,4DRQW@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1299514_3	33876.JNXY01000038_gene8104	3.598e-37	150.0	COG0483@1|root,COG0483@2|Bacteria,2H8ZM@201174|Actinobacteria	201174|Actinobacteria	G	Inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
MMS1_k127_1299514_2	1151117.AJLF01000001_gene1719	1.794e-40	158.0	COG0164@1|root,arCOG04121@2157|Archaea,2XWYC@28890|Euryarchaeota,242VW@183968|Thermococci	183968|Thermococci	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
MMS1_k127_1299514_7	1121945.ATXS01000003_gene1473	2.301e-05	49.0	COG1873@1|root,arCOG02155@2157|Archaea,2XYZ2@28890|Euryarchaeota,23WQZ@183963|Halobacteria	183963|Halobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
MMS1_k127_1299514_4	604354.TSIB_1199	2.467e-28	116.0	COG1581@1|root,arCOG01753@2157|Archaea,2XZH4@28890|Euryarchaeota,244BC@183968|Thermococci	183968|Thermococci	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
MMS1_k127_1299514_1	1006006.Mcup_0289	2.456e-53	192.0	COG1839@1|root,arCOG04298@2157|Archaea,2XQ7K@28889|Crenarchaeota	28889|Crenarchaeota	L	PFAM Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
MMS1_k127_1299514_0	1123376.AUIU01000013_gene1803	6.338e-121	400.0	COG1379@1|root,COG1379@2|Bacteria	2|Bacteria	-	-	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
MMS1_k127_1299514_6	1365176.N186_00510	5.629e-12	73.0	COG1750@1|root,arCOG01937@2157|Archaea,2XQAW@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM Lon protease (S16) C-terminal proteolytic domain	-	-	-	ko:K06870	-	-	-	-	ko00000	-	-	-	Lon_C
MMS1_k127_13519_4	573064.Mefer_0564	4.434e-33	131.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,23QHD@183939|Methanococci	183939|Methanococci	K	DEAD DEAH box helicase domain protein	-	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMS1_k127_13519_6	398512.JQKC01000019_gene3450	1.79e-23	114.0	COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,3WGN1@541000|Ruminococcaceae	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
MMS1_k127_13519_3	700598.Niako_1148	4.347e-45	187.0	COG0784@1|root,COG5002@1|root,COG5278@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,4PKV1@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg
MMS1_k127_13519_1	1042877.GQS_08995	9.917e-61	216.0	COG0513@1|root,arCOG00078@2157|Archaea,2XTFM@28890|Euryarchaeota,24333@183968|Thermococci	183968|Thermococci	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
MMS1_k127_13519_0	439481.Aboo_0966	1.783e-162	524.0	COG1690@1|root,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,3F2GK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	tRNA-splicing ligase RtcB	rtcB	GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,LAGLIDADG_3,RtcB
MMS1_k127_13519_8	396588.Tgr7_0574	1.126e-15	86.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1WXN5@135613|Chromatiales	135613|Chromatiales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
MMS1_k127_13519_2	877455.Metbo_0334	4.31e-52	198.0	COG1867@1|root,arCOG01219@2157|Archaea,2XTUF@28890|Euryarchaeota,23NVN@183925|Methanobacteria	183925|Methanobacteria	J	Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups	trm1	-	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
MMS1_k127_13519_9	868131.MSWAN_1780	3.037e-10	66.0	COG1849@1|root,arCOG01224@2157|Archaea,2Y279@28890|Euryarchaeota,23P92@183925|Methanobacteria	183925|Methanobacteria	S	Protein of unknown function (DUF357)	-	-	-	ko:K09728	-	-	-	-	ko00000	-	-	-	DUF357
MMS1_k127_13519_7	5888.CAK59941	9.61e-16	86.0	COG0592@1|root,KOG1636@2759|Eukaryota,3ZBEF@5878|Ciliophora	5878|Ciliophora	L	This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand	-	-	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
MMS1_k127_13519_5	1054217.TALC_01302	3.905e-29	126.0	COG1650@1|root,arCOG01616@2157|Archaea,2XUM0@28890|Euryarchaeota,241QQ@183967|Thermoplasmata	183967|Thermoplasmata	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
MMS1_k127_13519_10	999630.TUZN_0898	3.638e-08	66.0	arCOG03671@1|root,arCOG03672@1|root,arCOG03671@2157|Archaea,arCOG03672@2157|Archaea,2XQXR@28889|Crenarchaeota	28889|Crenarchaeota	E	Thermopsin	-	-	3.4.23.42	ko:K01385	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Thermopsin
MMS1_k127_1359404_2	251221.35213026	1.481e-45	190.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Kelch_1,Kelch_6
MMS1_k127_1359404_3	190486.XAC4199	1.229e-30	142.0	COG1520@1|root,COG1520@2|Bacteria,1QU2U@1224|Proteobacteria,1S1NX@1236|Gammaproteobacteria,1X7G8@135614|Xanthomonadales	135614|Xanthomonadales	S	dehydrogenase	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
MMS1_k127_1359404_0	1459636.NTE_03097	5.102e-62	229.0	arCOG03664@1|root,arCOG03664@2157|Archaea	2157|Archaea	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3
MMS1_k127_1359404_1	877455.Metbo_1812	2.588e-56	202.0	COG1704@1|root,arCOG04574@2157|Archaea,2XXB9@28890|Euryarchaeota,23PHV@183925|Methanobacteria	183925|Methanobacteria	S	PFAM LemA	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
MMS1_k127_1427277_4	673860.AciM339_0368	2.012e-16	87.0	COG1293@1|root,arCOG01695@2157|Archaea,2XTMF@28890|Euryarchaeota,3F2HS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
MMS1_k127_1427277_0	572546.Arcpr_0988	5.613e-86	291.0	COG1646@1|root,arCOG01085@2157|Archaea,2XTEC@28890|Euryarchaeota	28890|Euryarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	pcrB	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
MMS1_k127_1427277_3	1123326.JFBL01000004_gene2097	3.764e-22	108.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,43AN9@68525|delta/epsilon subdivisions,2YNUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS1_k127_1427277_5	171693.BN988_01657	1.228e-07	62.0	COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,23INT@182709|Oceanobacillus	91061|Bacilli	E	Proline dehydrogenase	fadM	GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
MMS1_k127_1427277_1	406327.Mevan_1488	1.295e-43	175.0	COG0585@1|root,arCOG04252@2157|Archaea,2XUTK@28890|Euryarchaeota,23Q6G@183939|Methanococci	183939|Methanococci	J	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
MMS1_k127_1427277_2	656024.FsymDg_4426	6.425e-26	109.0	COG1162@1|root,COG1162@2|Bacteria,2GU32@201174|Actinobacteria,4EWKA@85013|Frankiales	201174|Actinobacteria	S	RNHCP domain	-	-	-	-	-	-	-	-	-	-	-	-	RNHCP
MMS1_k127_1427277_6	273063.STK_08870	0.0002017	55.0	arCOG07351@1|root,arCOG07351@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1432830_3	373903.Hore_17190	2.686e-49	190.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,3WAPF@53433|Halanaerobiales	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_1432830_1	339860.Msp_0281	2.361e-86	301.0	COG1782@1|root,arCOG00543@2157|Archaea,2XTIM@28890|Euryarchaeota,23NSS@183925|Methanobacteria	183925|Methanobacteria	S	Beta-Casp domain	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_7,Lactamase_B_6,RMMBL
MMS1_k127_1432830_10	153721.MYP_4858	1.83e-08	65.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
MMS1_k127_1432830_6	313598.MED152_05425	4.124e-13	78.0	COG0204@1|root,COG0560@1|root,COG2937@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,COG2937@2|Bacteria,4NW8D@976|Bacteroidetes,1I6XY@117743|Flavobacteriia,3VV8T@52959|Polaribacter	976|Bacteroidetes	EI	haloacid dehalogenase-like hydrolase	-	-	2.3.1.51,3.1.3.3	ko:K00655,ko:K15781	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,HAD
MMS1_k127_1432830_9	880073.Calab_3490	8.059e-09	60.0	COG1254@1|root,COG1254@2|Bacteria,2NQ47@2323|unclassified Bacteria	2|Bacteria	C	Acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
MMS1_k127_1432830_7	1094980.Mpsy_2745	7.859e-10	65.0	arCOG05152@1|root,arCOG05152@2157|Archaea,2XZHZ@28890|Euryarchaeota,2N9VI@224756|Methanomicrobia	224756|Methanomicrobia	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_5
MMS1_k127_1432830_4	865861.AZSU01000003_gene2090	6.469e-22	102.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,36IQB@31979|Clostridiaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
MMS1_k127_1432830_0	386456.JQKN01000012_gene1035	8.142e-240	755.0	COG0443@1|root,arCOG03060@2157|Archaea,2XT86@28890|Euryarchaeota,23NSE@183925|Methanobacteria	183925|Methanobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
MMS1_k127_1432830_2	339860.Msp_1516	1.661e-76	269.0	COG0484@1|root,arCOG02846@2157|Archaea,2XV5D@28890|Euryarchaeota,23NRW@183925|Methanobacteria	183925|Methanobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS1_k127_1432830_8	69014.TK0031	1.32e-09	63.0	COG2023@1|root,arCOG04345@2157|Archaea,2XYX0@28890|Euryarchaeota,244AW@183968|Thermococci	183968|Thermococci	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp4	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rpr2
MMS1_k127_1432830_5	694440.JOMF01000006_gene409	2.448e-17	89.0	COG0693@1|root,arCOG00769@2157|Archaea,2XTPH@28890|Euryarchaeota,2N9U0@224756|Methanomicrobia	224756|Methanomicrobia	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
MMS1_k127_1453098_0	671065.MetMK1DRAFT_00015180	0.0002494	54.0	arCOG06052@1|root,arCOG06052@2157|Archaea,2XSHA@28889|Crenarchaeota	28889|Crenarchaeota	S	parallel beta-helix repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1469479_3	1236689.MMALV_00680	6.646e-09	60.0	COG2888@1|root,arCOG01989@2157|Archaea,2Y6XW@28890|Euryarchaeota,3F2UA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Domain of unknown function (DUF1610)	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	DUF1610
MMS1_k127_1469479_4	521011.Mpal_2591	0.0009201	45.0	COG2092@1|root,arCOG01988@2157|Archaea,2XYNW@28890|Euryarchaeota,2NA09@224756|Methanomicrobia	224756|Methanomicrobia	J	Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA	ef1b	-	-	ko:K03232	-	-	-	-	ko00000,ko03012	-	-	-	EF1_GNE
MMS1_k127_1469479_2	529709.PYCH_06190	4e-30	139.0	COG0419@1|root,arCOG00368@2157|Archaea,2XTC7@28890|Euryarchaeota,242NP@183968|Thermococci	183968|Thermococci	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex	rad50	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15,AAA_21,AAA_23,Rad50_zn_hook,SMC_N
MMS1_k127_1469479_0	1343739.PAP_07045	2.189e-121	412.0	COG0018@1|root,arCOG00487@2157|Archaea,2XTWP@28890|Euryarchaeota,24339@183968|Thermococci	183968|Thermococci	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
MMS1_k127_1469479_1	1006006.Mcup_1244	5.115e-38	155.0	COG0063@1|root,arCOG00018@2157|Archaea,2XPXN@28889|Crenarchaeota	28889|Crenarchaeota	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
MMS1_k127_1481692_0	1380355.JNIJ01000009_gene1635	2.769e-61	224.0	COG1389@1|root,COG1389@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
MMS1_k127_1519666_0	589924.Ferp_0902	1.715e-22	100.0	COG1308@1|root,arCOG04061@2157|Archaea,2XXYV@28890|Euryarchaeota,2476E@183980|Archaeoglobi	183980|Archaeoglobi	K	Contacts the emerging nascent chain on the ribosome	nac	-	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC
MMS1_k127_1519666_2	1230457.C476_13278	1.012e-06	55.0	COG2412@1|root,arCOG04051@2157|Archaea,2XYQK@28890|Euryarchaeota,23WV5@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
MMS1_k127_1519666_1	330779.Saci_1051	2.085e-20	106.0	COG1215@1|root,arCOG01391@2157|Archaea,2XQ2X@28889|Crenarchaeota	28889|Crenarchaeota	M	Glycosyl transferase family 21	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_tranf_2_3,Glyco_trans_2_3
MMS1_k127_1528854_2	511062.GU3_14820	5.598e-18	92.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1Y3UT@135624|Aeromonadales	135624|Aeromonadales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2
MMS1_k127_1528854_1	273057.SSO2568	1.666e-30	132.0	COG1814@1|root,arCOG01096@2157|Archaea,2XQFK@28889|Crenarchaeota	28889|Crenarchaeota	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
MMS1_k127_1528854_0	1459636.NTE_00421	1.82e-33	130.0	COG0760@1|root,arCOG07441@2157|Archaea,41SSK@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
MMS1_k127_152922_0	401526.TcarDRAFT_1926	1.182e-151	493.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H2FJ@909932|Negativicutes	909932|Negativicutes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
MMS1_k127_1575863_2	456442.Mboo_0667	3.731e-22	103.0	COG1047@1|root,arCOG00981@2157|Archaea,2XXFW@28890|Euryarchaeota,2NAZY@224756|Methanomicrobia	224756|Methanomicrobia	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
MMS1_k127_1575863_3	335543.Sfum_0412	3.458e-14	83.0	COG1575@1|root,COG1575@2|Bacteria,1PWVZ@1224|Proteobacteria,4349B@68525|delta/epsilon subdivisions,2X2PW@28221|Deltaproteobacteria,2MRJX@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
MMS1_k127_1575863_0	1288484.APCS01000119_gene779	6.62e-32	134.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMS1_k127_1575863_1	1416760.AYMS01000051_gene143	1.312e-26	117.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1HX52@117743|Flavobacteriia,47H4B@76831|Myroides	976|Bacteroidetes	Q	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMS1_k127_1593410_1	648996.Theam_0743	4.074e-56	216.0	COG1009@1|root,COG1009@2|Bacteria,2G3IY@200783|Aquificae	200783|Aquificae	CP	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L	nuoL1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
MMS1_k127_1593410_0	696369.KI912183_gene843	3.686e-56	213.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMS1_k127_1621944_7	523845.AQXV01000025_gene1487	2.458e-30	123.0	COG1990@1|root,arCOG04228@2157|Archaea,2XYRE@28890|Euryarchaeota,23QZN@183939|Methanococci	183939|Methanococci	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
MMS1_k127_1621944_2	673860.AciM339_1321	1.255e-46	183.0	COG1467@1|root,arCOG04110@2157|Archaea,2XUZF@28890|Euryarchaeota,3F2IZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priS	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02683	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_S
MMS1_k127_1621944_3	604354.TSIB_1186	6.45e-43	162.0	COG1632@1|root,arCOG04209@2157|Archaea,2XTJJ@28890|Euryarchaeota,242MQ@183968|Thermococci	183968|Thermococci	J	Belongs to the eukaryotic ribosomal protein eL15 family	rpl15e	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
MMS1_k127_1621944_0	1220534.B655_1960	1.786e-75	264.0	COG0087@1|root,arCOG04070@2157|Archaea,2XT9B@28890|Euryarchaeota,23NMA@183925|Methanobacteria	183925|Methanobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl3	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
MMS1_k127_1621944_4	358396.C445_11267	3.637e-40	159.0	COG0469@1|root,arCOG04071@2157|Archaea,2XTXX@28890|Euryarchaeota,23SFS@183963|Halobacteria	183963|Halobacteria	J	Forms part of the polypeptide exit tunnel	rpl4lp	-	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
MMS1_k127_1621944_11	374847.Kcr_1489	4.815e-16	81.0	COG0089@1|root,arCOG04072@2157|Archaea	2157|Archaea	J	Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome	rpl23	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
MMS1_k127_1621944_1	523850.TON_0069	3.453e-68	239.0	COG0090@1|root,arCOG04067@2157|Archaea,2XTCS@28890|Euryarchaeota,242MT@183968|Thermococci	183968|Thermococci	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rpl2	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
MMS1_k127_1621944_6	273063.STK_04260	1.538e-30	124.0	COG0185@1|root,arCOG04099@2157|Archaea,2XQBR@28889|Crenarchaeota	28889|Crenarchaeota	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rps19p	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
MMS1_k127_1621944_10	579137.Metvu_0227	2.982e-17	91.0	COG0091@1|root,arCOG04098@2157|Archaea,2XWGN@28890|Euryarchaeota,23QU0@183939|Methanococci	183939|Methanococci	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rpl22	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
MMS1_k127_1621944_5	1151117.AJLF01000002_gene49	3.425e-34	139.0	COG0092@1|root,arCOG04097@2157|Archaea,2XTHR@28890|Euryarchaeota,243EH@183968|Thermococci	183968|Thermococci	J	Binds the lower part of the 30S subunit head	rps3	GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
MMS1_k127_1621944_13	573063.Metin_0630	0.0006373	44.0	COG0255@1|root,arCOG00785@2157|Archaea,2Y1DQ@28890|Euryarchaeota	28890|Euryarchaeota	J	Belongs to the universal ribosomal protein uL29 family	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
MMS1_k127_1621944_8	386456.JQKN01000001_gene1755	1.668e-24	108.0	COG0023@1|root,arCOG04223@2157|Archaea,2XXW5@28890|Euryarchaeota,23PKF@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the SUI1 family	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
MMS1_k127_1621944_12	1459636.NTE_00654	7.501e-05	53.0	arCOG08773@1|root,arCOG08773@2157|Archaea,41SNY@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1621944_9	1338011.BD94_1214	2.48e-23	107.0	COG2755@1|root,COG2755@2|Bacteria,4NPMA@976|Bacteroidetes,1I2G1@117743|Flavobacteriia,34QEZ@308865|Elizabethkingia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMS1_k127_1669240_0	379066.GAU_3916	1.084e-17	89.0	COG0494@1|root,COG0494@2|Bacteria,1ZTQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
MMS1_k127_1669240_1	374847.Kcr_0622	2.685e-07	59.0	COG5340@1|root,arCOG04793@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
MMS1_k127_1716086_5	698757.Pogu_0885	1.948e-13	77.0	COG1430@1|root,arCOG03115@2157|Archaea	2157|Archaea	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
MMS1_k127_1716086_7	1459636.NTE_00627	0.0001589	49.0	COG0031@1|root,arCOG01430@2157|Archaea,41SYY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS1_k127_1716086_6	709991.Odosp_1431	1.697e-07	60.0	COG0237@1|root,COG0237@2|Bacteria	2|Bacteria	H	dephospho-CoA kinase activity	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,3.2.2.23,4.2.99.18	ko:K00859,ko:K08309,ko:K10563	ko00770,ko01100,ko03410,map00770,map01100,map03410	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01011,ko03400	-	GH23	iIT341.HP0831	CoaE
MMS1_k127_1716086_4	192952.MM_2218	8.039e-17	93.0	COG0438@1|root,arCOG01403@2157|Archaea,2XVZZ@28890|Euryarchaeota	28890|Euryarchaeota	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS1_k127_1716086_3	1293048.CBMB010000003_gene854	4.756e-23	114.0	COG3379@1|root,arCOG01377@2157|Archaea,2XUWW@28890|Euryarchaeota,23RZ5@183963|Halobacteria	183963|Halobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
MMS1_k127_1716086_2	289376.THEYE_A0693	1.235e-52	193.0	COG0177@1|root,COG0177@2|Bacteria,3J0K6@40117|Nitrospirae	40117|Nitrospirae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS1_k127_1716086_1	404589.Anae109_2770	4.193e-84	291.0	COG1697@1|root,COG1697@2|Bacteria,1NBFJ@1224|Proteobacteria,4314R@68525|delta/epsilon subdivisions,2WWNC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
MMS1_k127_1716086_0	70601.3256855	1.385e-154	499.0	COG0466@1|root,COG1372@1|root,arCOG02160@2157|Archaea,arCOG03158@2157|Archaea,2Y2YB@28890|Euryarchaeota,242YP@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
MMS1_k127_1736930_4	1163730.FFONT_0232	7.043e-13	73.0	COG4818@1|root,arCOG04344@2157|Archaea	2157|Archaea	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1736930_2	926692.AZYG01000007_gene1350	7.565e-101	343.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WB5Z@53433|Halanaerobiales	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
MMS1_k127_1736930_1	1387312.BAUS01000004_gene1626	4.53e-109	361.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,2KM0H@206350|Nitrosomonadales	206350|Nitrosomonadales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS1_k127_1736930_0	1121382.JQKG01000001_gene2289	1.365e-147	479.0	COG0821@1|root,COG0821@2|Bacteria,1WJ94@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
MMS1_k127_1736930_3	543734.LCABL_02270	1.92e-22	105.0	COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,3F4X7@33958|Lactobacillaceae	91061|Bacilli	G	Dehydrogenase	gntZ	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
MMS1_k127_173818_2	368408.Tpen_0748	6.663e-30	126.0	COG2078@1|root,arCOG01336@2157|Archaea,2XQG0@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
MMS1_k127_173818_0	269797.Mbar_A2765	2.698e-80	280.0	COG0389@1|root,arCOG04582@2157|Archaea,2XTZZ@28890|Euryarchaeota,2NAE4@224756|Methanomicrobia	224756|Methanomicrobia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis	dbh	-	2.7.7.7	ko:K04479	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
MMS1_k127_173818_1	351160.RCIX579	1.591e-32	137.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,2N9SR@224756|Methanomicrobia	224756|Methanomicrobia	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
MMS1_k127_173818_3	926561.KB900620_gene2882	6.446e-20	95.0	COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,24JZG@186801|Clostridia,3WASW@53433|Halanaerobiales	186801|Clostridia	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
MMS1_k127_1740849_7	931627.MycrhDRAFT_0732	7.175e-28	128.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,2HFES@201174|Actinobacteria,23E1D@1762|Mycobacteriaceae	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1740849_6	593117.TGAM_0904	1.066e-35	146.0	COG0030@1|root,arCOG04131@2157|Archaea,2XU1Q@28890|Euryarchaeota,242SR@183968|Thermococci	183968|Thermococci	J	Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
MMS1_k127_1740849_3	795359.TOPB45_0317	1.523e-51	190.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
MMS1_k127_1740849_0	1459636.NTE_02266	1.058e-119	406.0	COG0008@1|root,arCOG04302@2157|Archaea,41S5V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
MMS1_k127_1740849_5	1163730.FFONT_1027	1.927e-39	155.0	COG1047@1|root,arCOG00980@2157|Archaea,2XQ07@28889|Crenarchaeota	28889|Crenarchaeota	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
MMS1_k127_1740849_11	436308.Nmar_1236	3.406e-10	62.0	COG2093@1|root,arCOG04077@2157|Archaea,41SVE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
MMS1_k127_1740849_4	523845.AQXV01000046_gene850	3.058e-47	176.0	COG1095@1|root,arCOG00675@2157|Archaea,2XT6U@28890|Euryarchaeota,23Q1F@183939|Methanococci	183939|Methanococci	K	RNA binding S1 domain protein	-	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
MMS1_k127_1740849_8	926550.CLDAP_20380	1.447e-24	107.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi	200795|Chloroflexi	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMS1_k127_1740849_2	1379698.RBG1_1C00001G0708	8.044e-59	216.0	COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria	2|Bacteria	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS1_k127_1740849_10	742765.HMPREF9457_00322	3.149e-17	91.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,27UYR@189330|Dorea	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
MMS1_k127_1740849_1	439481.Aboo_1161	1.188e-60	218.0	COG1208@1|root,arCOG00666@2157|Archaea,2XUA6@28890|Euryarchaeota,3F2XH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Nucleotidyl transferase	graD	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
MMS1_k127_1749341_4	517418.Ctha_2646	2.738e-06	58.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	cdu2	-	-	ko:K05564,ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6,2.A.63.1	-	-	Na_H_Exchanger,Usp
MMS1_k127_1749341_2	406327.Mevan_1069	2.869e-26	115.0	COG2890@1|root,arCOG00109@2157|Archaea,2XWJZ@28890|Euryarchaeota,23QUN@183939|Methanococci	183939|Methanococci	J	PFAM methyltransferase small	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,PrmA
MMS1_k127_1749341_0	1459636.NTE_02652	9.422e-130	426.0	COG0520@1|root,arCOG00065@2157|Archaea,41SCV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
MMS1_k127_1749341_1	1122602.ATXP01000004_gene1865	8.334e-74	256.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,1W7E7@1268|Micrococcaceae	201174|Actinobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMS1_k127_1749341_3	1122212.AULO01000006_gene1669	1.813e-15	89.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,1XINT@135619|Oceanospirillales	135619|Oceanospirillales	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
MMS1_k127_1761019_0	1122919.KB905573_gene3565	3.805e-40	164.0	COG0464@1|root,COG0464@2|Bacteria,1UBVM@1239|Firmicutes,4ITDB@91061|Bacilli,277CY@186822|Paenibacillaceae	91061|Bacilli	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
MMS1_k127_17662_4	195522.BD01_1951	1.776e-15	86.0	COG1675@1|root,arCOG04270@2157|Archaea,2XSWK@28890|Euryarchaeota,2438P@183968|Thermococci	183968|Thermococci	K	Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes	tfe	-	-	ko:K03136	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIE_alpha
MMS1_k127_17662_3	1459636.NTE_02210	4.985e-49	187.0	COG0010@1|root,arCOG01700@2157|Archaea,41T23@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS1_k127_17662_1	2325.TKV_c00090	6.642e-219	696.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,42EPA@68295|Thermoanaerobacterales	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMS1_k127_17662_0	598659.NAMH_0664	6.258e-227	728.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2YMS4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMS1_k127_17662_2	304371.MCP_0129	1.517e-164	550.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,2N90P@224756|Methanomicrobia	224756|Methanomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMS1_k127_177099_0	671065.MetMK1DRAFT_00007870	9.058e-65	235.0	COG0477@1|root,arCOG02691@2157|Archaea	2157|Archaea	EGP	Major facilitator superfamily	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
MMS1_k127_180040_1	273075.Ta0351	1.711e-32	126.0	COG0183@1|root,arCOG01280@2157|Archaea,2Y85P@28890|Euryarchaeota,241YR@183967|Thermoplasmata	183967|Thermoplasmata	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS1_k127_180040_0	263820.PTO0737	1.164e-61	222.0	COG0451@1|root,arCOG03016@2157|Archaea,2Y6ZK@28890|Euryarchaeota,2428Z@183967|Thermoplasmata	183967|Thermoplasmata	M	NAD(P)H-binding	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
MMS1_k127_1804054_1	537007.BLAHAN_04834	9.432e-123	407.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
MMS1_k127_1804054_6	456320.Mvol_1025	9.764e-21	96.0	COG1911@1|root,arCOG01752@2157|Archaea,2Y0CU@28890|Euryarchaeota,23R1G@183939|Methanococci	183939|Methanococci	J	Belongs to the eukaryotic ribosomal protein eL30 family	rpl30e	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02908	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
MMS1_k127_1804054_4	70601.3257969	1.446e-42	160.0	COG0048@1|root,arCOG04255@2157|Archaea,2XX4A@28890|Euryarchaeota,243D7@183968|Thermococci	183968|Thermococci	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
MMS1_k127_1804054_3	391623.TERMP_00247	7.498e-48	180.0	COG0049@1|root,arCOG04254@2157|Archaea,2XTDC@28890|Euryarchaeota,242SU@183968|Thermococci	183968|Thermococci	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
MMS1_k127_1804054_0	69014.TK0309	2.151e-243	771.0	COG0480@1|root,arCOG01559@2157|Archaea,2XUMQ@28890|Euryarchaeota,243B9@183968|Thermococci	183968|Thermococci	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS1_k127_1804054_5	1459636.NTE_01204	2.615e-33	135.0	COG1358@1|root,arCOG01751@2157|Archaea,41SMS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs	rpl7ae	-	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
MMS1_k127_1804054_7	523850.TON_0953	3.546e-13	73.0	COG2053@1|root,arCOG04314@2157|Archaea,2XYMV@28890|Euryarchaeota,244JE@183968|Thermococci	183968|Thermococci	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
MMS1_k127_1804054_8	272557.APE_2379a	1.171e-06	52.0	COG2075@1|root,arCOG01950@2157|Archaea,2XREK@28889|Crenarchaeota	28889|Crenarchaeota	J	Binds to the 23S rRNA	rpl24e	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
MMS1_k127_1804054_2	986075.CathTA2_1277	1.342e-58	218.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli	91061|Bacilli	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
MMS1_k127_1804054_9	644281.MFS40622_0104	2.283e-05	49.0	COG2036@1|root,arCOG02144@2157|Archaea,2XZYK@28890|Euryarchaeota,23R9F@183939|Methanococci	183939|Methanococci	L	PFAM Transcription factor CBF NF-Y	-	-	-	-	-	-	-	-	-	-	-	-	CBFD_NFYB_HMF
MMS1_k127_1850546_5	266117.Rxyl_1197	1.362e-16	84.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4CQRQ@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
MMS1_k127_1850546_2	387631.Asulf_01803	9.422e-50	190.0	COG1005@1|root,arCOG01546@2157|Archaea,2XT7N@28890|Euryarchaeota,245YW@183980|Archaeoglobi	28890|Euryarchaeota	C	NADH ubiquinone oxidoreductase subunit 1 (chain H)	nuoH	-	1.5.98.3,1.6.5.3	ko:K00337,ko:K22163	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	NADHdh
MMS1_k127_1850546_0	387631.Asulf_01802	5.265e-96	326.0	COG0649@1|root,arCOG01548@2157|Archaea,2XTWF@28890|Euryarchaeota,245Y0@183980|Archaeoglobi	28890|Euryarchaeota	C	NADH ubiquinone oxidoreductase 49 kD subunit 7	nuoCD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
MMS1_k127_1850546_6	1225785.CM001983_gene2369	1.183e-08	61.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,2JCJT@204037|Dickeya	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iECDH10B_1368.ECDH10B_2448,iECDH1ME8569_1439.ECDH1ME8569_2223,iETEC_1333.ETEC_2421,iEcDH1_1363.EcDH1_1371,iPC815.YPO2553,iUMNK88_1353.UMNK88_2836	Complex1_30kDa,Complex1_49kDa
MMS1_k127_1850546_1	326427.Cagg_1630	1.224e-51	188.0	COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi,374UM@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB2	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMS1_k127_1850546_7	673860.AciM339_0379	1.105e-06	51.0	arCOG06415@1|root,arCOG06415@2157|Archaea	2157|Archaea	L	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	zf-HIT
MMS1_k127_1850546_8	490899.DKAM_1126	2.377e-05	55.0	arCOG05924@1|root,arCOG05924@2157|Archaea,2XRA9@28889|Crenarchaeota	28889|Crenarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1850546_4	868131.MSWAN_1852	6.44e-17	88.0	COG1936@1|root,arCOG01038@2157|Archaea,2XX2A@28890|Euryarchaeota,23P4V@183925|Methanobacteria	183925|Methanobacteria	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
MMS1_k127_1850546_3	1229909.NSED_09545	1.966e-23	110.0	COG1746@1|root,arCOG04249@2157|Archaea,41S76@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
MMS1_k127_1882217_1	273075.Ta1414	1.394e-21	96.0	COG0425@1|root,arCOG02062@2157|Archaea,2XZUG@28890|Euryarchaeota	28890|Euryarchaeota	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	TusA
MMS1_k127_1882217_3	1068980.ARVW01000001_gene6271	3.932e-12	70.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4DXX5@85010|Pseudonocardiales	201174|Actinobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
MMS1_k127_1882217_2	273075.Ta0563	6.096e-15	74.0	COG2452@1|root,arCOG03164@2157|Archaea,2XW65@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM Resolvase domain	-	GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K07450	-	-	-	-	ko00000	-	-	-	HTH_17,Resolvase
MMS1_k127_1882217_0	1138822.PL11_03815	1.577e-25	114.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,3F41F@33958|Lactobacillaceae	91061|Bacilli	Q	Isochorismatase family	pncA	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
MMS1_k127_1890739_2	309799.DICTH_0616	8.65e-69	240.0	COG1793@1|root,COG1793@2|Bacteria	2|Bacteria	L	dna ligase	lig	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
MMS1_k127_1890739_1	573063.Metin_0058	2.225e-98	332.0	COG0206@1|root,arCOG02201@2157|Archaea,2XSV8@28890|Euryarchaeota,23QJU@183939|Methanococci	183939|Methanococci	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMS1_k127_1890739_0	573063.Metin_0058	3.568e-100	336.0	COG0206@1|root,arCOG02201@2157|Archaea,2XSV8@28890|Euryarchaeota,23QJU@183939|Methanococci	183939|Methanococci	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMS1_k127_1890739_4	579137.Metvu_0875	2.883e-35	139.0	COG0231@1|root,arCOG04277@2157|Archaea,2XX3E@28890|Euryarchaeota,23R14@183939|Methanococci	183939|Methanococci	J	Functions by promoting the formation of the first peptide bond	eif5a	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	EFP_N,eIF-5a
MMS1_k127_1890739_7	374847.Kcr_1337	0.0002345	49.0	COG2004@1|root,arCOG04182@2157|Archaea	2157|Archaea	J	Belongs to the eukaryotic ribosomal protein eS24 family	rps24e	-	-	ko:K02974,ko:K09735	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S24e
MMS1_k127_1890739_6	456442.Mboo_0241	7.736e-08	54.0	COG1998@1|root,arCOG04183@2157|Archaea,2XZZ0@28890|Euryarchaeota,2NA60@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
MMS1_k127_1890739_5	545697.HMPREF0216_00728	3.593e-08	63.0	COG1266@1|root,COG1266@2|Bacteria,1V822@1239|Firmicutes,24CBM@186801|Clostridia,36KB1@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,Abi
MMS1_k127_1890739_3	644281.MFS40622_0975	9.367e-36	145.0	COG0565@1|root,arCOG01018@2157|Archaea,2XUIY@28890|Euryarchaeota,23QQD@183939|Methanococci	183939|Methanococci	J	TIGRFAM RNA methyltransferase, TrmH family, group 1	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
MMS1_k127_1890739_8	1343739.PAP_01465	0.0003462	48.0	COG2450@1|root,arCOG02263@2157|Archaea,2Y3YU@28890|Euryarchaeota,2449H@183968|Thermococci	183968|Thermococci	D	Pfam:DUF552	-	-	-	ko:K09152	-	-	-	-	ko00000	-	-	-	SepF
MMS1_k127_1927502_4	243164.DET0400	6.447e-42	165.0	COG0337@1|root,COG0337@2|Bacteria,2G5K8@200795|Chloroflexi,34D03@301297|Dehalococcoidia	301297|Dehalococcoidia	H	3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
MMS1_k127_1927502_0	1198449.ACAM_0865	9.138e-104	372.0	COG0464@1|root,arCOG01308@2157|Archaea,2XPXJ@28889|Crenarchaeota	28889|Crenarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
MMS1_k127_1927502_1	717231.Flexsi_0211	1.015e-60	227.0	COG1008@1|root,COG1008@2|Bacteria,2GF24@200930|Deferribacteres	200930|Deferribacteres	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMS1_k127_1927502_7	224324.aq_1542	8.127e-08	63.0	COG0170@1|root,COG0170@2|Bacteria,2G5BD@200783|Aquificae	200783|Aquificae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1927502_5	224719.Abm4_1285	2.452e-25	122.0	COG3356@1|root,arCOG04351@2157|Archaea,2XVEY@28890|Euryarchaeota,23NN7@183925|Methanobacteria	183925|Methanobacteria	S	Predicted membrane protein (DUF2070)	-	-	-	ko:K08979	-	-	-	-	ko00000	-	-	-	DUF2070
MMS1_k127_1927502_3	1449080.JQMV01000003_gene233	8.918e-51	188.0	COG0020@1|root,COG0020@2|Bacteria,1WI97@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
MMS1_k127_1927502_2	484019.THA_138	2.716e-59	210.0	COG0503@1|root,COG0503@2|Bacteria,2GCSE@200918|Thermotogae	200918|Thermotogae	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
MMS1_k127_1927502_6	565033.GACE_0907	1.084e-13	72.0	COG2101@1|root,arCOG01764@2157|Archaea,2XTTR@28890|Euryarchaeota,246U8@183980|Archaeoglobi	183980|Archaeoglobi	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	tbp	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
MMS1_k127_1935005_0	273075.Ta0959	2.823e-141	462.0	COG1007@1|root,arCOG01540@2157|Archaea,2XSY7@28890|Euryarchaeota,241P2@183967|Thermoplasmata	183967|Thermoplasmata	C	Proton-conducting membrane transporter	-	-	1.5.98.3,1.6.5.3	ko:K00343,ko:K22169	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	Proton_antipo_M
MMS1_k127_1954588_0	1365176.N186_00990	1.324e-53	202.0	COG0436@1|root,arCOG01131@2157|Archaea	2157|Archaea	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS1_k127_1973651_2	593117.TGAM_1606	2.609e-09	59.0	COG0124@1|root,arCOG00404@2157|Archaea,2XVRC@28890|Euryarchaeota,243YF@183968|Thermococci	183968|Thermococci	J	Histidyl-tRNA synthetase	-	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
MMS1_k127_1973651_1	273116.14325275	1.351e-30	124.0	COG3439@1|root,arCOG02761@2157|Archaea,2Y7BY@28890|Euryarchaeota,242F7@183967|Thermoplasmata	183967|Thermoplasmata	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
MMS1_k127_1973651_0	263820.PTO0832	7.301e-55	201.0	arCOG06968@1|root,arCOG06968@2157|Archaea,2Y3RN@28890|Euryarchaeota,24294@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1973651_3	710696.Intca_3543	0.0009594	44.0	COG0599@1|root,COG0599@2|Bacteria,2IRPW@201174|Actinobacteria,4FJCM@85021|Intrasporangiaceae	201174|Actinobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS1_k127_1979787_0	673860.AciM339_0619	5.524e-106	353.0	COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,3F2HE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Intein_splicing,Rad51
MMS1_k127_1983325_0	273116.14324581	1.272e-117	389.0	COG0348@1|root,arCOG03697@2157|Archaea	2157|Archaea	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2020108_1	273116.14325669	1.282e-11	70.0	COG0500@1|root,arCOG01793@2157|Archaea,2Y1JK@28890|Euryarchaeota,242DW@183967|Thermoplasmata	183967|Thermoplasmata	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS1_k127_2020108_0	529709.PYCH_16390	4.359e-28	123.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y7MQ@28890|Euryarchaeota,243HH@183968|Thermococci	183968|Thermococci	T	KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
MMS1_k127_2020108_2	1280390.CBQR020000114_gene2977	4.776e-07	64.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS1_k127_2022402_1	1343739.PAP_02715	3.147e-197	629.0	COG0086@1|root,arCOG04257@2157|Archaea,2XTBZ@28890|Euryarchaeota,242YY@183968|Thermococci	183968|Thermococci	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA1	-	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMS1_k127_2022402_0	877455.Metbo_2397	1.386e-197	634.0	COG0085@1|root,arCOG01762@2157|Archaea,2XU1X@28890|Euryarchaeota,23NMQ@183925|Methanobacteria	183925|Methanobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB1	-	2.7.7.6	ko:K03044,ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
MMS1_k127_2022402_2	523845.AQXV01000027_gene1197	6.824e-80	275.0	COG0085@1|root,arCOG01762@2157|Archaea,2XU9Q@28890|Euryarchaeota,23Q3N@183939|Methanococci	183939|Methanococci	K	Belongs to the RNA polymerase beta chain family	rpoB2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03045	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3
MMS1_k127_2036830_0	1123386.AUIW01000005_gene1549	1.049e-163	544.0	COG0209@1|root,COG0209@2|Bacteria,1WJ14@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
MMS1_k127_2036830_8	1232430.CAVG010000064_gene653	8.364e-39	150.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,4GXFP@90964|Staphylococcaceae	91061|Bacilli	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
MMS1_k127_2036830_6	604354.TSIB_1503	2.441e-60	219.0	COG0024@1|root,arCOG01001@2157|Archaea,2XT8G@28890|Euryarchaeota,242WX@183968|Thermococci	183968|Thermococci	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMS1_k127_2036830_1	342949.PNA2_0859	1.983e-152	511.0	COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,242Z2@183968|Thermococci	183968|Thermococci	L	DNA polymerase	pol	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1,Intein_splicing,LAGLIDADG_3
MMS1_k127_2036830_10	386456.JQKN01000008_gene1364	7.912e-16	82.0	COG0864@1|root,arCOG01008@2157|Archaea,2XWHW@28890|Euryarchaeota	28890|Euryarchaeota	K	Transcriptional regulator	nikR1	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
MMS1_k127_2036830_2	671065.MetMK1DRAFT_00025640	3.188e-111	368.0	arCOG06008@1|root,arCOG06008@2157|Archaea,2XRQ9@28889|Crenarchaeota	28889|Crenarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2036830_9	614083.AWQR01000040_gene757	3.63e-19	90.0	COG0350@1|root,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,2VRTX@28216|Betaproteobacteria,4AE2A@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
MMS1_k127_2036830_4	868131.MSWAN_1447	1.89e-80	286.0	COG5253@1|root,arCOG04169@2157|Archaea,2XT9A@28890|Euryarchaeota,23NV1@183925|Methanobacteria	183925|Methanobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
MMS1_k127_2036830_7	511051.CSE_09380	8.292e-56	216.0	COG4986@1|root,COG4986@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	opuAB	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
MMS1_k127_2036830_5	515635.Dtur_0768	2.062e-71	249.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria	2|Bacteria	P	C-terminal AAA-associated domain	abcT3	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
MMS1_k127_2036830_11	515635.Dtur_0768	7.601e-10	66.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria	2|Bacteria	P	C-terminal AAA-associated domain	abcT3	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
MMS1_k127_2036830_3	273075.Ta0343	1.407e-94	319.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota	28890|Euryarchaeota	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2,5.1.3.20	ko:K01784,ko:K03274	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	M00064,M00361,M00362,M00632	R00291,R02984,R05176	RC00289,RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF692.Mbar_A0021	Epimerase,GDP_Man_Dehyd
MMS1_k127_2058012_3	1220534.B655_2241	2.128e-11	65.0	COG3585@1|root,arCOG00228@2157|Archaea,2Y1B5@28890|Euryarchaeota,23PTM@183925|Methanobacteria	183925|Methanobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	TOBE
MMS1_k127_2058012_2	673860.AciM339_1383	1.429e-12	75.0	COG1714@1|root,arCOG03633@2157|Archaea,2Y6YZ@28890|Euryarchaeota,3F2YA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMS1_k127_2058012_1	880072.Desac_1106	5.805e-24	103.0	2E32K@1|root,32Y2U@2|Bacteria,1NJTE@1224|Proteobacteria,42WY3@68525|delta/epsilon subdivisions,2WSR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2058012_0	264732.Moth_1651	2.355e-28	117.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,42GNH@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM FeS cluster assembly scaffold protein NifU	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMS1_k127_2087401_2	573063.Metin_1442	7.374e-69	236.0	COG5256@1|root,arCOG01561@2157|Archaea,2XTNM@28890|Euryarchaeota,23Q4E@183939|Methanococci	183939|Methanococci	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMS1_k127_2087401_3	768679.TTX_0012	2.052e-31	125.0	COG0051@1|root,arCOG01758@2157|Archaea,2XQTY@28889|Crenarchaeota	28889|Crenarchaeota	J	Involved in the binding of tRNA to the ribosomes	rps10	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
MMS1_k127_2087401_0	572546.Arcpr_0357	1.284e-103	346.0	COG1899@1|root,arCOG04142@2157|Archaea,2XSTD@28890|Euryarchaeota,2461M@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	dys	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
MMS1_k127_2087401_1	877455.Metbo_2336	6.99e-102	341.0	COG1405@1|root,arCOG01981@2157|Archaea,2XT0Z@28890|Euryarchaeota,23NWZ@183925|Methanobacteria	183925|Methanobacteria	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
MMS1_k127_2109799_0	1042877.GQS_09950	7.953e-30	123.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,242KT@183968|Thermococci	183968|Thermococci	D	Cell division protein 48 (CDC48) N-terminal domain	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
MMS1_k127_2121825_1	1158602.I590_01679	2.987e-09	63.0	2BM4Y@1|root,32FNE@2|Bacteria,1TZWU@1239|Firmicutes,4I96A@91061|Bacilli,4B3TF@81852|Enterococcaceae	91061|Bacilli	S	Helix-turn-helix of insertion element transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1_2
MMS1_k127_2121825_0	1041142.ATTP01000043_gene5298	7.223e-36	143.0	COG5565@1|root,COG5565@2|Bacteria,1R6R3@1224|Proteobacteria,2U1P9@28211|Alphaproteobacteria,4BDQ9@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	DNA packaging protein gp2	gp2	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
MMS1_k127_2128730_15	1123508.JH636443_gene5018	6.011e-19	92.0	COG3324@1|root,COG3324@2|Bacteria,2J3W8@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
MMS1_k127_2128730_5	1131269.AQVV01000007_gene1068	2.732e-78	267.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	yagB	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
MMS1_k127_2128730_12	273063.STK_05500	9.313e-33	141.0	COG1524@1|root,arCOG01378@2157|Archaea,2XQRC@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
MMS1_k127_2128730_14	671065.MetMK1DRAFT_00018210	5.274e-25	112.0	COG2020@1|root,arCOG03580@2157|Archaea	2157|Archaea	O	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
MMS1_k127_2128730_18	439481.Aboo_1149	3.305e-10	68.0	COG1499@1|root,arCOG04149@2157|Archaea,2XUAI@28890|Euryarchaeota,3F2MW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	NMD3 family	nmd3	-	-	ko:K07562	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko03009	-	-	-	NMD3
MMS1_k127_2128730_9	186497.PF0174	1.877e-47	191.0	COG0342@1|root,arCOG03055@2157|Archaea,2XU5A@28890|Euryarchaeota,243BT@183968|Thermococci	183968|Thermococci	U	Protein-export membrane protein SecD	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMS1_k127_2128730_13	1220534.B655_0962	2.312e-32	140.0	COG0341@1|root,arCOG03054@2157|Archaea,2XTMX@28890|Euryarchaeota,23NZ5@183925|Methanobacteria	183925|Methanobacteria	U	Involved in protein export	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMS1_k127_2128730_0	243232.MJ_1332	2.818e-101	342.0	COG0012@1|root,arCOG00357@2157|Archaea,2XTZG@28890|Euryarchaeota,23Q3F@183939|Methanococci	183939|Methanococci	J	GTP-binding protein HSR1-related	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
MMS1_k127_2128730_7	1151119.KB895493_gene1475	5.788e-51	188.0	COG1215@1|root,COG1215@2|Bacteria,2GP1D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS1_k127_2128730_16	868131.MSWAN_1947	3.564e-16	90.0	COG2064@1|root,arCOG01811@2157|Archaea,2Y71N@28890|Euryarchaeota,23P0K@183925|Methanobacteria	183925|Methanobacteria	N	Type II secretion system	gspF2	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
MMS1_k127_2128730_17	342949.PNA2_1270	1.323e-15	89.0	COG2064@1|root,arCOG01812@2157|Archaea,2Y671@28890|Euryarchaeota,242WY@183968|Thermococci	183968|Thermococci	N	Type II secretion system (T2SS), protein F	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
MMS1_k127_2128730_8	1123368.AUIS01000003_gene1806	1.637e-50	186.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,LUD_dom,SnoaL_3,SnoaL_4
MMS1_k127_2128730_6	1123405.AUMM01000004_gene701	7.152e-78	273.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,26NC6@186821|Sporolactobacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS1_k127_2128730_1	273068.TTE0549	3.707e-100	340.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,42EVW@68295|Thermoanaerobacterales	186801|Clostridia	I	Belongs to the thiolase family	thlA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS1_k127_2128730_11	1121289.JHVL01000016_gene718	5.399e-46	175.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS1_k127_2128730_10	224324.aq_1660	3.521e-46	172.0	COG0663@1|root,COG0663@2|Bacteria,2G3ZR@200783|Aquificae	200783|Aquificae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
MMS1_k127_2128730_4	1210884.HG799467_gene13470	3.99e-80	282.0	COG1960@1|root,COG1960@2|Bacteria,2IXMD@203682|Planctomycetes	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_2128730_19	796606.BMMGA3_08295	4.534e-07	57.0	COG3427@1|root,COG3427@2|Bacteria,1V6I3@1239|Firmicutes,4HJJD@91061|Bacilli	91061|Bacilli	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
MMS1_k127_2128730_3	666510.ASAC_1488	2.962e-84	299.0	COG1290@1|root,arCOG01721@2157|Archaea	2157|Archaea	C	Cytochrome b subunit of the bc complex	petB2	-	-	ko:K00412,ko:K15879	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
MMS1_k127_2128730_2	263820.PTO1483	2.105e-87	299.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota	28890|Euryarchaeota	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
MMS1_k127_2130682_1	1123386.AUIW01000001_gene324	5.526e-32	127.0	COG1694@1|root,COG1694@2|Bacteria,1WK7E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
MMS1_k127_2130682_0	604354.TSIB_0089	3.447e-35	142.0	COG0466@1|root,COG1372@1|root,arCOG02160@2157|Archaea,arCOG03158@2157|Archaea,2Y2YB@28890|Euryarchaeota,242YP@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
MMS1_k127_214598_2	351160.RRC93	3.982e-06	53.0	arCOG01059@1|root,arCOG01059@2157|Archaea,2Y0H1@28890|Euryarchaeota,2N9Y0@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_214598_1	323259.Mhun_1437	1.166e-22	102.0	COG0328@1|root,arCOG02942@2157|Archaea,2XT22@28890|Euryarchaeota	28890|Euryarchaeota	L	COG0328 Ribonuclease HI	rnhA2	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
MMS1_k127_214598_0	700598.Niako_0694	1.126e-67	248.0	COG0457@1|root,COG1222@1|root,COG0457@2|Bacteria,COG1222@2|Bacteria,4NGR6@976|Bacteroidetes,1IWHT@117747|Sphingobacteriia	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA,TPR_19,TPR_8
MMS1_k127_2192290_1	272557.APE_0900.1	5.766e-13	71.0	COG2388@1|root,arCOG06090@2157|Archaea,2XQY0@28889|Crenarchaeota	28889|Crenarchaeota	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
MMS1_k127_2192290_2	647113.Metok_0573	0.000121	53.0	COG0681@1|root,arCOG01739@2157|Archaea,2XYJI@28890|Euryarchaeota,23R22@183939|Methanococci	183939|Methanococci	U	PFAM Peptidase S24 S26A S26B, conserved region	-	GO:0003674,GO:0003824,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
MMS1_k127_2192290_0	523845.AQXV01000054_gene1652	5.676e-102	370.0	COG1196@1|root,arCOG00371@2157|Archaea,2XSVK@28890|Euryarchaeota,23Q4M@183939|Methanococci	183939|Methanococci	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
MMS1_k127_2192942_0	604354.TSIB_1965	9.721e-92	311.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,242W1@183968|Thermococci	183968|Thermococci	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2,Succ_CoA_lig
MMS1_k127_2192942_2	387631.Asulf_01085	1.329e-33	138.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,246Y6@183980|Archaeoglobi	183980|Archaeoglobi	C	CoA binding domain	-	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
MMS1_k127_2192942_1	243232.MJ_0047	2.532e-90	312.0	COG1236@1|root,arCOG00541@2157|Archaea,2XTIU@28890|Euryarchaeota,23Q9Q@183939|Methanococci	183939|Methanococci	J	PFAM beta-lactamase domain protein	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
MMS1_k127_2192942_3	304371.MCP_2990	2.346e-06	54.0	COG1599@1|root,arCOG01510@2157|Archaea,2XTJP@28890|Euryarchaeota,2N93V@224756|Methanomicrobia	224756|Methanomicrobia	L	PFAM nucleic acid binding, OB-fold, tRNA helicase-type	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
MMS1_k127_2231215_4	246969.TAM4_949	6.042e-27	115.0	COG0081@1|root,arCOG04289@2157|Archaea,2XTJF@28890|Euryarchaeota,242ZJ@183968|Thermococci	183968|Thermococci	J	Binds directly to 23S rRNA. Probably involved in E site tRNA release	rpl1	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
MMS1_k127_2231215_3	572546.Arcpr_1735	1.09e-31	135.0	COG0244@1|root,arCOG04288@2157|Archaea,2XU7C@28890|Euryarchaeota,245X9@183980|Archaeoglobi	183980|Archaeoglobi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
MMS1_k127_2231215_5	573063.Metin_1010	2.346e-16	82.0	COG2058@1|root,arCOG04287@2157|Archaea,2XYQ9@28890|Euryarchaeota,23R5H@183939|Methanococci	183939|Methanococci	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl12	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02869	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s
MMS1_k127_2231215_6	1265505.ATUG01000002_gene2770	0.0003352	48.0	COG4231@1|root,COG4231@2|Bacteria,1N6WI@1224|Proteobacteria,42V3I@68525|delta/epsilon subdivisions,2WRKA@28221|Deltaproteobacteria,2MKZT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
MMS1_k127_2231215_1	1151117.AJLF01000001_gene1738	2.444e-53	199.0	COG2520@1|root,arCOG00033@2157|Archaea,2XTSI@28890|Euryarchaeota,242WN@183968|Thermococci	183968|Thermococci	J	Met-10+ like-protein	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
MMS1_k127_2231215_2	693661.Arcve_1306	9.731e-46	181.0	COG2237@1|root,arCOG04151@2157|Archaea,2XTV5@28890|Euryarchaeota,2463A@183980|Archaeoglobi	183980|Archaeoglobi	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
MMS1_k127_2231215_7	1538295.JY96_11040	0.00062	50.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,1KKN6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
MMS1_k127_2231215_0	1343739.PAP_00410	3.25e-92	322.0	COG4962@1|root,arCOG01819@2157|Archaea,2Y8F5@28890|Euryarchaeota,242XB@183968|Thermococci	183968|Thermococci	U	type II secretion system protein	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Intein_splicing,LAGLIDADG_3,T2SSE
MMS1_k127_2236411_0	309803.CTN_0163	1.435e-05	52.0	COG2110@1|root,COG2256@1|root,COG2110@2|Bacteria,COG2256@2|Bacteria,2GC7M@200918|Thermotogae	200918|Thermotogae	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,Macro,MgsA_C,RuvB_N
MMS1_k127_2237019_1	1070774.J07HN4v3_02154	9.509e-25	109.0	COG1094@1|root,arCOG04150@2157|Archaea,2XUHX@28890|Euryarchaeota,23S45@183963|Halobacteria	183963|Halobacteria	J	RNA-binding protein (contains KH domains)	dim2	-	-	ko:K06961	-	-	-	-	ko00000,ko03009	-	-	-	KH_1
MMS1_k127_2237019_0	70601.3257993	5.886e-131	436.0	COG1389@1|root,arCOG01165@2157|Archaea,2XTZQ@28890|Euryarchaeota,242PK@183968|Thermococci	183968|Thermococci	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
MMS1_k127_2237019_2	453591.Igni_0221	1.932e-09	70.0	COG0433@1|root,arCOG00286@2157|Archaea,2XSPP@28889|Crenarchaeota	28889|Crenarchaeota	L	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
MMS1_k127_2263875_1	1379698.RBG1_1C00001G0542	1.233e-138	454.0	COG0504@1|root,COG0504@2|Bacteria,2NNVG@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iNJ661.Rv1699,iPC815.YPO3377	CTP_synth_N,GATase
MMS1_k127_2263875_5	186497.PF0058	9.245e-31	130.0	COG0463@1|root,arCOG00894@2157|Archaea,2XWXA@28890|Euryarchaeota,242RY@183968|Thermococci	183968|Thermococci	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
MMS1_k127_2263875_9	490899.DKAM_0506	2.13e-08	67.0	COG2244@1|root,arCOG02209@2157|Archaea,2XQBN@28889|Crenarchaeota	28889|Crenarchaeota	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
MMS1_k127_2263875_3	269797.Mbar_A2493	2.059e-39	169.0	arCOG03981@1|root,arCOG03981@2157|Archaea,2Y4K9@28890|Euryarchaeota,2NB6J@224756|Methanomicrobia	224756|Methanomicrobia	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2263875_12	1459636.NTE_01688	8.661e-05	49.0	COG3269@1|root,arCOG01641@2157|Archaea	2157|Archaea	J	RNA-binding protein contains TRAM domain	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
MMS1_k127_2263875_2	406327.Mevan_1573	2.784e-52	192.0	COG0638@1|root,arCOG00970@2157|Archaea,2XUIZ@28890|Euryarchaeota,23QK3@183939|Methanococci	183939|Methanococci	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
MMS1_k127_2263875_0	386456.JQKN01000019_gene1316	2.082e-185	599.0	COG1782@1|root,arCOG00543@2157|Archaea,2XTIM@28890|Euryarchaeota,23NSS@183925|Methanobacteria	183925|Methanobacteria	S	Beta-Casp domain	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_7,Lactamase_B_6,RMMBL
MMS1_k127_2263875_7	502558.EGYY_24900	5.387e-17	84.0	2EG6W@1|root,339YS@2|Bacteria,2HW59@201174|Actinobacteria,4CY0M@84998|Coriobacteriia	84998|Coriobacteriia	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
MMS1_k127_2263875_6	1280685.AUKC01000005_gene2083	1.377e-21	98.0	COG4997@1|root,COG4997@2|Bacteria,1VEG6@1239|Firmicutes,24QRF@186801|Clostridia	186801|Clostridia	S	phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,MazG-like
MMS1_k127_2263875_4	1123073.KB899245_gene121	4.442e-38	146.0	2B1QU@1|root,31U6H@2|Bacteria,1N3JH@1224|Proteobacteria,1S7B4@1236|Gammaproteobacteria,1X7EM@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
MMS1_k127_2263875_8	1283284.AZUK01000002_gene2775	9.348e-12	72.0	COG1443@1|root,COG1443@2|Bacteria,1P8AM@1224|Proteobacteria,1RQA3@1236|Gammaproteobacteria,1Y4NG@135624|Aeromonadales	135624|Aeromonadales	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS1_k127_2263875_11	552811.Dehly_0115	4.621e-05	50.0	COG0337@1|root,COG0337@2|Bacteria,2G5K8@200795|Chloroflexi,34D03@301297|Dehalococcoidia	301297|Dehalococcoidia	H	3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
MMS1_k127_2272322_0	565033.GACE_1731	1.513e-145	468.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,246Y7@183980|Archaeoglobi	183980|Archaeoglobi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
MMS1_k127_2282641_5	272844.PAB0777	7.322e-14	76.0	COG5378@1|root,arCOG02121@2157|Archaea,2XZRH@28890|Euryarchaeota,244UG@183968|Thermococci	183968|Thermococci	V	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_2
MMS1_k127_2282641_6	391623.TERMP_02109	0.0003575	48.0	arCOG07235@1|root,arCOG07235@2157|Archaea,2Y3YM@28890|Euryarchaeota,244IE@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2282641_0	985053.VMUT_0434	7.184e-154	495.0	COG0538@1|root,arCOG01164@2157|Archaea,2XPUT@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM isocitrate dehydrogenase, NADP-dependent	idh	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS1_k127_2282641_2	869210.Marky_1069	4.84e-106	356.0	COG0372@1|root,COG0372@2|Bacteria,1WI65@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS1_k127_2282641_4	420247.Msm_0214	4.657e-52	197.0	COG0498@1|root,arCOG01434@2157|Archaea,2XT84@28890|Euryarchaeota,23NPP@183925|Methanobacteria	183925|Methanobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS1_k127_2282641_1	102125.Xen7305DRAFT_00052760	2.126e-108	366.0	COG0579@1|root,COG0579@2|Bacteria,1G4FU@1117|Cyanobacteria,3VITJ@52604|Pleurocapsales	1117|Cyanobacteria	C	Malate:quinone oxidoreductase (Mqo)	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
MMS1_k127_2282641_3	265729.GS18_0205410	4.165e-100	334.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus	91061|Bacilli	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	citB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06730	Aconitase,Aconitase_C
MMS1_k127_2296974_0	1132509.C447_06351	6.732e-06	54.0	COG1591@1|root,arCOG00919@2157|Archaea,2XTHF@28890|Euryarchaeota,23TR3@183963|Halobacteria	183963|Halobacteria	L	A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products	hjc	-	3.1.22.4	ko:K03552	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Hjc
MMS1_k127_2301341_1	406327.Mevan_0837	9.477e-25	107.0	COG0341@1|root,arCOG03054@2157|Archaea,2XTMX@28890|Euryarchaeota,23Q46@183939|Methanococci	183939|Methanococci	U	Involved in protein export	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMS1_k127_2301341_0	868131.MSWAN_1297	2.541e-47	187.0	COG0342@1|root,arCOG03055@2157|Archaea,2XU5A@28890|Euryarchaeota,23NSV@183925|Methanobacteria	183925|Methanobacteria	U	Protein-export membrane protein SecD	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMS1_k127_2303128_0	273075.Ta1060m	2.656e-47	175.0	COG0402@1|root,arCOG00695@2157|Archaea,2XTJS@28890|Euryarchaeota,241JE@183967|Thermoplasmata	183967|Thermoplasmata	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMS1_k127_2319895_4	649639.Bcell_0837	6.63e-05	50.0	COG1670@1|root,COG1670@2|Bacteria,1TQS3@1239|Firmicutes,4HDCG@91061|Bacilli,1ZETV@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS1_k127_2319895_2	1194526.A284_11580	2.266e-10	64.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,4GYUN@90964|Staphylococcaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	ydaF	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
MMS1_k127_2319895_0	1408422.JHYF01000004_gene1588	6.11e-71	251.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia,36F1A@31979|Clostridiaceae	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS1_k127_2319895_3	936596.HMPREF1495_0572	7.365e-08	63.0	COG4587@1|root,COG4587@2|Bacteria,1UZTC@1239|Firmicutes,24E7Q@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
MMS1_k127_2319895_1	1034769.KB910518_gene2977	1.062e-16	89.0	COG3694@1|root,COG3694@2|Bacteria,1UZ6K@1239|Firmicutes,4HCYU@91061|Bacilli,26VHX@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
MMS1_k127_2325940_2	176946.XP_007426007.1	3.033e-05	53.0	COG1796@1|root,KOG2534@2759|Eukaryota,39ENV@33154|Opisthokonta,3BCKK@33208|Metazoa,3CWDE@33213|Bilateria,47ZXN@7711|Chordata,48ZBV@7742|Vertebrata	33208|Metazoa	L	Polymerase (DNA directed), lambda	POLL	GO:0000724,GO:0000725,GO:0000726,GO:0002200,GO:0002376,GO:0002377,GO:0002440,GO:0002520,GO:0002566,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006284,GO:0006287,GO:0006289,GO:0006302,GO:0006303,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016445,GO:0016446,GO:0016740,GO:0016772,GO:0016779,GO:0016829,GO:0016835,GO:0018130,GO:0019438,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0048731,GO:0048856,GO:0050896,GO:0051575,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K03512	ko03410,ko03450,map03410,map03450	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	BRCT_2,DNA_pol_B_palm,DNA_pol_B_thumb,DNA_pol_lambd_f,HHH_8
MMS1_k127_2325940_1	1121468.AUBR01000099_gene3089	9.068e-22	103.0	2CDFK@1|root,2Z8BH@2|Bacteria,1V43D@1239|Firmicutes,24KG0@186801|Clostridia	186801|Clostridia	H	DNA N-6-adenine-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dam
MMS1_k127_2325940_0	1122173.AXVL01000018_gene452	2.739e-46	183.0	COG0863@1|root,COG0863@2|Bacteria,37A63@32066|Fusobacteria	32066|Fusobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
MMS1_k127_2341247_1	273116.14325565	9.148e-103	350.0	COG0513@1|root,arCOG00558@2157|Archaea,2XUS4@28890|Euryarchaeota,241NG@183967|Thermoplasmata	183967|Thermoplasmata	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
MMS1_k127_2341247_2	273075.Ta0147	2.888e-80	282.0	COG3408@1|root,arCOG03287@2157|Archaea,2XU8W@28890|Euryarchaeota	28890|Euryarchaeota	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
MMS1_k127_2341247_3	1174528.JH992898_gene2587	1.053e-37	159.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria,1JHRU@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_2341247_0	891968.Anamo_1586	6.423e-228	728.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,3TA4P@508458|Synergistetes	508458|Synergistetes	G	PFAM glycosyl transferase family 20	-	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
MMS1_k127_2392458_1	1046627.BZARG_812	5.682e-05	53.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,1HWW9@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
MMS1_k127_2392458_0	666510.ASAC_0068	2.996e-09	62.0	COG0472@1|root,arCOG03199@2157|Archaea,2XPXP@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.15	ko:K01001	ko00510,ko01100,map00510,map01100	M00055	R05969	RC00002	ko00000,ko00001,ko00002,ko01000,ko01003	-	-	-	Glycos_transf_4
MMS1_k127_2397679_0	273116.14324307	5.029e-192	616.0	COG0038@1|root,arCOG02569@2157|Archaea,2XW6N@28890|Euryarchaeota,24226@183967|Thermoplasmata	183967|Thermoplasmata	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
MMS1_k127_2397679_1	1122182.KB903833_gene5326	2.408e-10	67.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4D8Y3@85008|Micromonosporales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS1_k127_240132_0	591019.Shell_1101	4.972e-219	704.0	COG1201@1|root,arCOG00557@2157|Archaea,2XQ43@28889|Crenarchaeota	28889|Crenarchaeota	L	DEAD DEAH box helicase	-	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMS1_k127_240132_5	868131.MSWAN_0770	6.448e-39	154.0	COG1407@1|root,arCOG01150@2157|Archaea,2XU3W@28890|Euryarchaeota,23PJA@183925|Methanobacteria	183925|Methanobacteria	S	Phosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
MMS1_k127_240132_1	436308.Nmar_0658	2.944e-143	469.0	COG0008@1|root,arCOG00402@2157|Archaea,41SFI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
MMS1_k127_240132_6	880073.Calab_1294	1.249e-15	84.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
MMS1_k127_240132_3	1229909.NSED_08125	1.229e-54	201.0	COG0506@1|root,arCOG06322@2157|Archaea,41SY1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
MMS1_k127_240132_4	1128398.Curi_c15480	1.124e-40	166.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,267UQ@186813|unclassified Clostridiales	186801|Clostridia	S	Peptidase M16 inactive domain	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS1_k127_240132_8	386043.lwe1275	2.829e-06	55.0	COG1051@1|root,COG1051@2|Bacteria,1VGSW@1239|Firmicutes,4HM0W@91061|Bacilli,26KNU@186820|Listeriaceae	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS1_k127_240132_2	374847.Kcr_1079	1.746e-82	286.0	COG0142@1|root,arCOG01726@2157|Archaea	2157|Archaea	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS1_k127_2424261_1	579137.Metvu_1545	2.181e-11	68.0	COG1460@1|root,arCOG01016@2157|Archaea,2XXZX@28890|Euryarchaeota,23R3J@183939|Methanococci	183939|Methanococci	K	PFAM RNA polymerase Rpb4	-	-	2.7.7.6	ko:K03051	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb4
MMS1_k127_2424261_0	70601.3258258	8.346e-48	178.0	COG1491@1|root,arCOG04130@2157|Archaea,2XXAI@28890|Euryarchaeota,242KI@183968|Thermococci	183968|Thermococci	J	Protein of unknown function (DUF655)	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
MMS1_k127_24251_3	374847.Kcr_0621	5.033e-15	83.0	COG2253@1|root,arCOG03839@2157|Archaea	2157|Archaea	K	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	ko:K09144	-	-	-	-	ko00000	-	-	-	AbiEii
MMS1_k127_24251_1	743525.TSC_c17890	3.353e-46	171.0	COG1225@1|root,COG1225@2|Bacteria,1WI9E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS1_k127_24251_0	1229909.NSED_05490	4.107e-174	575.0	COG0308@1|root,arCOG02969@2157|Archaea,41SJH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256,ko:K13722	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
MMS1_k127_24251_2	608538.HTH_1226	3.576e-29	126.0	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	FAD_binding_6,Fer2,HTH_8,NAD_binding_1,PAS_8,Sigma54_activat
MMS1_k127_2426431_2	573063.Metin_0253	2.899e-65	238.0	COG0470@1|root,arCOG00470@2157|Archaea,2XT81@28890|Euryarchaeota,23Q03@183939|Methanococci	183939|Methanococci	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcL	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,Rad17
MMS1_k127_2426431_0	573063.Metin_1118	1.001e-97	339.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,23QRD@183939|Methanococci	183939|Methanococci	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,tRNA-synt_2d
MMS1_k127_2426431_1	386456.JQKN01000002_gene2422	2.921e-91	318.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,23NUT@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
MMS1_k127_2434295_4	326427.Cagg_1361	4.519e-20	99.0	COG0467@1|root,COG0467@2|Bacteria,2G8TX@200795|Chloroflexi,376XI@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Circadian clock protein KaiC central region	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
MMS1_k127_2434295_5	1041930.Mtc_2137	2.349e-17	95.0	COG1107@1|root,arCOG06880@1|root,arCOG00429@2157|Archaea,arCOG06880@2157|Archaea,2XTZ2@28890|Euryarchaeota,2N92F@224756|Methanomicrobia	224756|Methanomicrobia	L	acid binding OB-fold tRNA helicase-type	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHH,DnaJ_CXXCXGXG,S1,tRNA_anti-codon
MMS1_k127_2434295_0	224325.AF_2316	1.175e-175	571.0	COG1964@1|root,arCOG00933@2157|Archaea,2XTMK@28890|Euryarchaeota,245R2@183980|Archaeoglobi	183980|Archaeoglobi	L	Radical SAM domain protein	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
MMS1_k127_2434295_2	608538.HTH_1195	1.323e-69	252.0	COG0064@1|root,COG0064@2|Bacteria,2G3P7@200783|Aquificae	200783|Aquificae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
MMS1_k127_2434295_1	330779.Saci_1330	9.545e-80	282.0	COG0154@1|root,arCOG01717@2157|Archaea,2XPYP@28889|Crenarchaeota	28889|Crenarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS1_k127_2434295_6	1123354.AUDR01000012_gene1906	5.738e-05	49.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,1KRUT@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Glu-tRNAGln amidotransferase C subunit	-	-	-	-	-	-	-	-	-	-	-	-	Glu-tRNAGln
MMS1_k127_2434295_3	399550.Smar_1256	3.546e-40	157.0	COG1498@1|root,arCOG01923@2157|Archaea,2XPYC@28889|Crenarchaeota	28889|Crenarchaeota	J	PFAM Pre-mRNA processing ribonucleoprotein, binding	-	-	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Nop
MMS1_k127_2436146_0	439481.Aboo_0717	4.643e-34	146.0	COG0477@1|root,arCOG00130@2157|Archaea,2Y719@28890|Euryarchaeota,3F34W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2441058_1	1294142.CINTURNW_3989	5.207e-10	62.0	COG4974@1|root,COG4974@2|Bacteria,1V4TR@1239|Firmicutes,24C07@186801|Clostridia,36DGH@31979|Clostridiaceae	186801|Clostridia	L	site-specific recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
MMS1_k127_2441058_0	1206732.BAGD01000280_gene6507	5.216e-16	78.0	2AFEW@1|root,315EW@2|Bacteria,2HJS6@201174|Actinobacteria,4G79Z@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2493343_1	374847.Kcr_1200	9.1e-112	374.0	COG0017@1|root,arCOG00406@2157|Archaea	2157|Archaea	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K09759,ko:K22503	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS1_k127_2493343_2	273075.Ta0056	1.179e-43	165.0	COG0461@1|root,arCOG00029@2157|Archaea,2XVNG@28890|Euryarchaeota,241R4@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
MMS1_k127_2493343_4	36080.S2J0Q3	1.667e-31	130.0	COG0494@1|root,2S254@2759|Eukaryota,39ZYW@33154|Opisthokonta,3P53K@4751|Fungi,1GU9K@112252|Fungi incertae sedis	4751|Fungi	L	NUDIX domain	-	-	3.6.1.55,3.6.1.56	ko:K03574,ko:K17816	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
MMS1_k127_2493343_0	930945.SiRe_0937	4.527e-134	442.0	arCOG00144@1|root,arCOG00144@2157|Archaea,2XQ4R@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2493343_6	1297742.A176_06772	1.421e-10	70.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,434AF@68525|delta/epsilon subdivisions,2X23S@28221|Deltaproteobacteria,2YVSR@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
MMS1_k127_2493343_3	1444712.BN1013_00717	1.315e-41	162.0	COG1986@1|root,COG1986@2|Bacteria	2|Bacteria	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	yjjX	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	iECO111_1330.ECO111_5255	NTPase_I-T
MMS1_k127_2493343_5	1455608.JDTH01000001_gene3009	3.13e-19	97.0	COG0455@1|root,arCOG00589@2157|Archaea,2XT20@28890|Euryarchaeota,23SDD@183963|Halobacteria	183963|Halobacteria	D	COG0455 ATPases involved in chromosome partitioning	-	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,ParA
MMS1_k127_2493746_0	742767.HMPREF9456_02233	8.341e-102	345.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,2FPZR@200643|Bacteroidia,22WPN@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 15	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
MMS1_k127_2510890_0	273116.14325562	6.826e-148	482.0	COG0591@1|root,arCOG01316@2157|Archaea,2Y79Y@28890|Euryarchaeota,241YE@183967|Thermoplasmata	183967|Thermoplasmata	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	-
MMS1_k127_2510890_11	666510.ASAC_0133	1.454e-15	79.0	arCOG03694@1|root,arCOG03694@2157|Archaea,2XRJF@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
MMS1_k127_2510890_12	1280706.AUJE01000025_gene1168	3.319e-08	61.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4H4B2@909932|Negativicutes	909932|Negativicutes	F	Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
MMS1_k127_2510890_3	497964.CfE428DRAFT_4783	2.104e-84	295.0	COG3214@1|root,COG3214@2|Bacteria,46UTW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
MMS1_k127_2510890_4	1121085.AUCI01000006_gene1440	2.11e-61	220.0	COG2132@1|root,COG2132@2|Bacteria,1TS46@1239|Firmicutes,4ITAE@91061|Bacilli,1ZG10@1386|Bacillus	91061|Bacilli	Q	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
MMS1_k127_2510890_9	273057.SSO0014	5.715e-31	126.0	COG4272@1|root,arCOG05396@2157|Archaea,2XS2W@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function (DUF1634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
MMS1_k127_2510890_2	273116.14325418	4.718e-90	304.0	COG0730@1|root,arCOG02050@2157|Archaea,2XYUE@28890|Euryarchaeota,241RV@183967|Thermoplasmata	183967|Thermoplasmata	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS1_k127_2510890_6	485913.Krac_1995	4.093e-42	160.0	COG5649@1|root,COG5649@2|Bacteria	2|Bacteria	E	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
MMS1_k127_2510890_5	1123073.KB899242_gene1305	8.151e-47	171.0	COG5646@1|root,COG5646@2|Bacteria,1QB2A@1224|Proteobacteria,1T6JI@1236|Gammaproteobacteria,1X7N4@135614|Xanthomonadales	135614|Xanthomonadales	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
MMS1_k127_2510890_10	1380390.JIAT01000011_gene2283	1.029e-22	102.0	COG0346@1|root,COG0346@2|Bacteria,2II8J@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS1_k127_2510890_7	1459636.NTE_01931	3.028e-32	130.0	COG1846@1|root,arCOG03182@2157|Archaea	2157|Archaea	K	Regulatory protein MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2,Methyltransf_11
MMS1_k127_2510890_1	1249627.D779_1354	5.666e-93	323.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,1S5ET@1236|Gammaproteobacteria,1WYQP@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
MMS1_k127_2510890_8	1459636.NTE_00446	2.566e-31	125.0	COG0640@1|root,arCOG01681@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS1_k127_2515615_0	1205753.A989_19553	0.0007844	42.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1X3AP@135614|Xanthomonadales	135614|Xanthomonadales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
MMS1_k127_2521829_0	263820.PTO1483	2.296e-90	308.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota	28890|Euryarchaeota	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
MMS1_k127_2521829_1	1006006.Mcup_0824	1.642e-07	59.0	COG0456@1|root,arCOG00833@2157|Archaea,2XRDG@28889|Crenarchaeota	28889|Crenarchaeota	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS1_k127_2567537_0	8479.XP_005286770.1	8.216e-29	129.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,48B0V@7711|Chordata,499U9@7742|Vertebrata,4CK8P@8459|Testudines	33208|Metazoa	L	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
MMS1_k127_2588310_0	1459636.NTE_02653	5.31e-11	63.0	COG0822@1|root,arCOG02077@2157|Archaea,41SPT@651137|Thaumarchaeota	651137|Thaumarchaeota	C	SUF system FeS assembly protein	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMS1_k127_2603372_8	1151117.AJLF01000002_gene46	6.187e-20	91.0	COG0186@1|root,arCOG04096@2157|Archaea,2XYPE@28890|Euryarchaeota,2446S@183968|Thermococci	183968|Thermococci	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
MMS1_k127_2603372_5	1151117.AJLF01000002_gene45	3.457e-29	121.0	COG0093@1|root,arCOG04095@2157|Archaea,2XWM6@28890|Euryarchaeota,2441V@183968|Thermococci	183968|Thermococci	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
MMS1_k127_2603372_6	1041930.Mtc_1334	7.507e-23	102.0	COG0198@1|root,arCOG04094@2157|Archaea,2XXV4@28890|Euryarchaeota,2N9XR@224756|Methanomicrobia	224756|Methanomicrobia	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl24	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,Ribosomal_L26
MMS1_k127_2603372_7	572478.Vdis_1522	1.642e-22	106.0	COG1471@1|root,arCOG04093@2157|Archaea,2XPPZ@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the eukaryotic ribosomal protein eS4 family	rps4e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
MMS1_k127_2603372_2	565033.GACE_2234	2.144e-33	135.0	COG0094@1|root,arCOG04092@2157|Archaea,2XTRN@28890|Euryarchaeota,24640@183980|Archaeoglobi	183980|Archaeoglobi	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
MMS1_k127_2603372_10	6334.EFV57357	3.311e-10	63.0	COG0199@1|root,KOG3506@2759|Eukaryota,3A8G0@33154|Opisthokonta,3BUAG@33208|Metazoa,3DAJH@33213|Bilateria	33208|Metazoa	J	ribosomal protein S29	RPS29	GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0010941,GO:0010942,GO:0012505,GO:0015031,GO:0015833,GO:0015935,GO:0016020,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022626,GO:0022627,GO:0030867,GO:0031090,GO:0031974,GO:0031981,GO:0031984,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042175,GO:0042788,GO:0042886,GO:0042981,GO:0043043,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046872,GO:0046907,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0065007,GO:0070013,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0098552,GO:0098554,GO:0098556,GO:0098562,GO:0098588,GO:0098827,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02980	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
MMS1_k127_2603372_3	634498.mru_0867	3.194e-30	123.0	COG0096@1|root,arCOG04091@2157|Archaea,2XWMU@28890|Euryarchaeota,23P1I@183925|Methanobacteria	183925|Methanobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rps8	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
MMS1_k127_2603372_1	386456.JQKN01000001_gene1746	6.576e-35	141.0	COG0097@1|root,arCOG04090@2157|Archaea,2XTIS@28890|Euryarchaeota,23PAC@183925|Methanobacteria	183925|Methanobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
MMS1_k127_2603372_11	4899.EPX71633	0.0009234	48.0	COG1717@1|root,KOG0878@2759|Eukaryota,3A0DJ@33154|Opisthokonta,3P2W4@4751|Fungi,3QV38@4890|Ascomycota,3MCPU@451866|Taphrinomycotina	4751|Fungi	J	60S ribosomal protein L32	RPL32	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L32e
MMS1_k127_2603372_9	1163730.FFONT_0502	5.092e-12	72.0	COG2147@1|root,arCOG04089@2157|Archaea,2XQXG@28889|Crenarchaeota	28889|Crenarchaeota	J	Binds to the 23S rRNA	rpl19e	-	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
MMS1_k127_2603372_4	573064.Mefer_0677	3.917e-30	126.0	COG0256@1|root,arCOG04088@2157|Archaea,2XTWT@28890|Euryarchaeota,23Q3R@183939|Methanococci	183939|Methanococci	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rpl18	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18_c,Ribosomal_L5e
MMS1_k127_2603372_0	1041930.Mtc_1343	6.222e-53	192.0	COG0098@1|root,arCOG04087@2157|Archaea,2XUQU@28890|Euryarchaeota,2N954@224756|Methanomicrobia	224756|Methanomicrobia	J	With S4 and S12 plays an important role in translational accuracy	rps5	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
MMS1_k127_2642157_1	694429.Pyrfu_0169	1.68e-05	47.0	COG1491@1|root,arCOG04130@2157|Archaea,2XQPC@28889|Crenarchaeota	28889|Crenarchaeota	J	Protein of unknown function (DUF655)	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
MMS1_k127_2642157_0	529709.PYCH_05980	2.164e-07	56.0	COG2139@1|root,arCOG04129@2157|Archaea,2XXZB@28890|Euryarchaeota,244BJ@183968|Thermococci	183968|Thermococci	J	Belongs to the eukaryotic ribosomal protein eL21 family	rpl21e	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02889	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21e
MMS1_k127_2642712_1	1122128.AUEE01000005_gene925	6.927e-56	200.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,4GXSF@90964|Staphylococcaceae	91061|Bacilli	J	asparaginyl-tRNA	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS1_k127_2642712_4	671065.MetMK1DRAFT_00017820	2.957e-09	67.0	COG0288@1|root,arCOG02860@2157|Archaea	2157|Archaea	P	carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
MMS1_k127_2642712_5	868131.MSWAN_0123	7.993e-06	53.0	COG1145@1|root,arCOG02180@2157|Archaea,2XV84@28890|Euryarchaeota,23PCF@183925|Methanobacteria	183925|Methanobacteria	C	4Fe-4S dicluster domain	fwdF	-	-	ko:K00205	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002	-	-	-	Fer4
MMS1_k127_2642712_2	1325130.HFN_2292	6.193e-27	117.0	COG3545@1|root,COG3545@2|Bacteria,1RKTI@1224|Proteobacteria,42TNI@68525|delta/epsilon subdivisions,2YQ2R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
MMS1_k127_2642712_6	720554.Clocl_3933	1.065e-05	58.0	COG5305@1|root,COG5305@2|Bacteria,1UM1P@1239|Firmicutes,25G8T@186801|Clostridia	186801|Clostridia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS1_k127_2642712_0	5932.XP_004029845.1	5.107e-85	293.0	COG0162@1|root,KOG2144@2759|Eukaryota,3ZBI3@5878|Ciliophora	5878|Ciliophora	J	tRNA synthetases class I (W and Y)	-	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
MMS1_k127_26916_5	1120977.JHUX01000003_gene1632	3.482e-09	64.0	28V22@1|root,2ZH5I@2|Bacteria,1P9G0@1224|Proteobacteria,1SUBS@1236|Gammaproteobacteria,3NP6K@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_26916_4	339860.Msp_1154	4.893e-32	134.0	COG1994@1|root,arCOG00614@2157|Archaea,2XX7B@28890|Euryarchaeota,23P2G@183925|Methanobacteria	183925|Methanobacteria	S	PFAM Peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_26916_0	694429.Pyrfu_0250	1.728e-207	677.0	COG0495@1|root,arCOG00809@2157|Archaea,2XPP2@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
MMS1_k127_26916_3	767817.Desgi_1547	1.885e-34	148.0	COG0438@1|root,COG0438@2|Bacteria,1UYSU@1239|Firmicutes	1239|Firmicutes	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_26916_1	69014.TK0549	1.921e-83	298.0	COG2192@1|root,arCOG01188@2157|Archaea,2XVCE@28890|Euryarchaeota,242ZR@183968|Thermococci	183968|Thermococci	O	carbamoyl transferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
MMS1_k127_26916_2	1499967.BAYZ01000090_gene4943	1.87e-57	211.0	COG0535@1|root,COG0535@2|Bacteria,2NPKA@2323|unclassified Bacteria	2|Bacteria	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
MMS1_k127_2692848_0	243231.GSU2351	4.206e-106	354.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6	ko:K01535,ko:K12955	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.24,3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMS1_k127_269611_3	273075.Ta0027	1.232e-77	270.0	COG0656@1|root,arCOG01619@2157|Archaea	2157|Archaea	S	COG0656 Aldo keto reductases, related to diketogulonate reductase	yafB	-	1.1.1.346	ko:K06222	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
MMS1_k127_269611_4	933801.Ahos_1018	4.805e-40	158.0	COG1226@1|root,arCOG01958@2157|Archaea	2157|Archaea	P	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
MMS1_k127_269611_5	29540.C481_05695	1.828e-32	139.0	COG1537@1|root,arCOG01741@2157|Archaea,2XTQ4@28890|Euryarchaeota,23RY3@183963|Halobacteria	183963|Halobacteria	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	-	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_2,eRF1_3
MMS1_k127_269611_2	573064.Mefer_0206	4.844e-102	342.0	COG0206@1|root,arCOG02201@2157|Archaea,2XSV8@28890|Euryarchaeota,23QJU@183939|Methanococci	183939|Methanococci	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMS1_k127_269611_1	269797.Mbar_A1642	2.589e-152	500.0	COG1796@1|root,arCOG00305@2157|Archaea,2XT14@28890|Euryarchaeota,2N90T@224756|Methanomicrobia	224756|Methanomicrobia	L	Helix-hairpin-helix domain	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
MMS1_k127_269611_0	273075.Ta0776	1.187e-160	516.0	COG0334@1|root,arCOG01352@2157|Archaea,2XU0F@28890|Euryarchaeota,241PE@183967|Thermoplasmata	183967|Thermoplasmata	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
MMS1_k127_269611_6	1343739.PAP_09655	1.23e-05	52.0	COG1992@1|root,arCOG00021@2157|Archaea,2XT4Y@28890|Euryarchaeota,243AG@183968|Thermococci	183968|Thermococci	H	Thiamine-phosphate synthase	-	-	-	ko:K22206	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,Terminase_5,ThiP_synth
MMS1_k127_269611_7	397948.Cmaq_1945	0.0006524	42.0	COG4830@1|root,arCOG04305@2157|Archaea,2XQSV@28889|Crenarchaeota	28889|Crenarchaeota	J	Ribosomal protein S26e	rps26e	-	-	ko:K02976	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S26e
MMS1_k127_269919_0	368408.Tpen_0288	2.771e-50	190.0	COG0423@1|root,arCOG00405@2157|Archaea,2XPSF@28889|Crenarchaeota	28889|Crenarchaeota	J	PFAM tRNA synthetase, class II (G, H, P and S)	glyS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
MMS1_k127_269919_1	642492.Clole_3334	2.926e-44	172.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
MMS1_k127_269919_3	573064.Mefer_0741	1.06e-17	90.0	COG2178@1|root,arCOG04318@2157|Archaea,2XXNP@28890|Euryarchaeota,23QXW@183939|Methanococci	183939|Methanococci	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	Translin
MMS1_k127_269919_6	1504981.KO116_0756	0.0006041	51.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,1RXZ7@1236|Gammaproteobacteria,1XKVB@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
MMS1_k127_269919_4	1177154.Y5S_02572	8.28e-05	54.0	COG0433@1|root,COG0433@2|Bacteria,1NRBN@1224|Proteobacteria,1RU1X@1236|Gammaproteobacteria,1XIPD@135619|Oceanospirillales	135619|Oceanospirillales	D	Domain of unknown function DUF87	-	-	-	ko:K19175	-	-	-	-	ko00000,ko02048	-	-	-	DUF87
MMS1_k127_269919_2	868131.MSWAN_0692	9.723e-35	146.0	COG0517@1|root,arCOG00607@2157|Archaea,2XTE5@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the peptidase M50B family	-	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
MMS1_k127_269919_5	273075.Ta0537m	0.0002588	50.0	COG1407@1|root,arCOG01150@2157|Archaea,2XU3W@28890|Euryarchaeota,241SF@183967|Thermoplasmata	183967|Thermoplasmata	S	Calcineurin-like phosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
MMS1_k127_2701554_0	1121422.AUMW01000037_gene2865	1.054e-12	80.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,CagE_TrbE_VirB,DUF87
MMS1_k127_2739532_0	192952.MM_0259	2.336e-106	353.0	COG0129@1|root,arCOG04045@2157|Archaea,2XSW2@28890|Euryarchaeota,2N992@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2069	ILVD_EDD
MMS1_k127_2739532_1	1033743.CAES01000046_gene268	3.324e-35	142.0	COG0491@1|root,COG0491@2|Bacteria,1V4VK@1239|Firmicutes,4I071@91061|Bacilli	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS1_k127_2749369_0	263820.PTO1020	2.687e-67	241.0	COG0494@1|root,COG1573@1|root,arCOG00905@2157|Archaea,arCOG01078@2157|Archaea,2XUVI@28890|Euryarchaeota,242GY@183967|Thermoplasmata	183967|Thermoplasmata	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS1_k127_2749369_3	1293047.CBMA010000014_gene833	5.471e-11	70.0	COG0346@1|root,arCOG02708@2157|Archaea,2XYB6@28890|Euryarchaeota,23WDX@183963|Halobacteria	183963|Halobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
MMS1_k127_2749369_2	1051632.TPY_3219	2.104e-11	75.0	2DGGT@1|root,2ZVX8@2|Bacteria,1V6AM@1239|Firmicutes	1239|Firmicutes	S	Peptidase A4 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A4
MMS1_k127_2749369_4	673862.BABL1_1004	2.608e-07	65.0	COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,42ZEZ@68525|delta/epsilon subdivisions,2WT5G@28221|Deltaproteobacteria	1224|Proteobacteria	M	Immunoglobulin-like repeats containing protein domain	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Big_3_5,DUF4347,He_PIG,RHS_repeat
MMS1_k127_2749369_1	1172185.KB911513_gene4635	2.776e-40	174.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4G0TI@85025|Nocardiaceae	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
MMS1_k127_2752187_0	1041930.Mtc_0628	7.165e-116	383.0	COG1089@1|root,arCOG01373@2157|Archaea,2XUVY@28890|Euryarchaeota,2N9AM@224756|Methanomicrobia	224756|Methanomicrobia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS1_k127_2752187_1	706587.Desti_4858	2.225e-96	327.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
MMS1_k127_2752187_2	1380394.JADL01000007_gene4586	1.246e-81	286.0	COG2227@1|root,COG2227@2|Bacteria,1QU62@1224|Proteobacteria,2TW17@28211|Alphaproteobacteria,2JYYK@204441|Rhodospirillales	204441|Rhodospirillales	H	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
MMS1_k127_2752187_3	589924.Ferp_1910	9.884e-21	100.0	COG3379@1|root,arCOG01377@2157|Archaea,2XUWW@28890|Euryarchaeota,2468N@183980|Archaeoglobi	183980|Archaeoglobi	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
MMS1_k127_2766657_6	386456.JQKN01000007_gene3245	5.114e-58	218.0	COG4962@1|root,arCOG01819@2157|Archaea,2Y8F5@28890|Euryarchaeota,23NT6@183925|Methanobacteria	183925|Methanobacteria	U	secretion system protein	gspE	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
MMS1_k127_2766657_0	1056495.Calag_0990	1.805e-219	696.0	COG1053@1|root,arCOG00571@2157|Archaea,2XPP3@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS1_k127_2766657_5	1056495.Calag_0993	1.254e-72	258.0	COG0479@1|root,arCOG00962@2157|Archaea,2XQDR@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
MMS1_k127_2766657_1	1121091.AUMP01000002_gene2230	3.512e-134	441.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli	91061|Bacilli	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
MMS1_k127_2766657_4	70601.3258098	8.481e-79	279.0	COG0552@1|root,arCOG01227@2157|Archaea,2XUBI@28890|Euryarchaeota,242QW@183968|Thermococci	183968|Thermococci	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
MMS1_k127_2766657_13	195522.BD01_0864	1.32e-06	56.0	COG1730@1|root,arCOG01341@2157|Archaea,2Y1IQ@28890|Euryarchaeota,2446C@183968|Thermococci	183968|Thermococci	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04797	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin
MMS1_k127_2766657_7	439481.Aboo_0028	1.254e-35	143.0	COG1976@1|root,arCOG04176@2157|Archaea,2XU7N@28890|Euryarchaeota,3F2QF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
MMS1_k127_2766657_3	555079.Toce_0364	8.246e-84	285.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,42EWQ@68295|Thermoanaerobacterales	186801|Clostridia	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	mtaP	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMS1_k127_2766657_10	985053.VMUT_1610	2.515e-18	98.0	COG1361@1|root,arCOG02089@2157|Archaea,2XRI8@28889|Crenarchaeota	28889|Crenarchaeota	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2766657_11	1437425.CSEC_2423	2.345e-14	85.0	COG0842@1|root,COG0842@2|Bacteria,2JGI3@204428|Chlamydiae	204428|Chlamydiae	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS1_k127_2766657_2	1183377.Py04_1391	6.197e-85	292.0	COG1131@1|root,arCOG00196@2157|Archaea,2Y7M5@28890|Euryarchaeota,245M5@183968|Thermococci	183968|Thermococci	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS1_k127_2766657_14	1408433.JHXV01000019_gene1947	0.0007801	47.0	COG1695@1|root,COG1695@2|Bacteria,4NQBA@976|Bacteroidetes,1I39C@117743|Flavobacteriia,2PB1S@246874|Cryomorphaceae	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS1_k127_2766657_8	272844.PAB1411	3.632e-31	134.0	COG0463@1|root,arCOG00894@2157|Archaea,2XUJ6@28890|Euryarchaeota,242XZ@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS1_k127_2766657_9	573063.Metin_1389	1.845e-30	126.0	COG0197@1|root,arCOG04113@2157|Archaea,2XTHT@28890|Euryarchaeota,23QNQ@183939|Methanococci	183939|Methanococci	J	Belongs to the universal ribosomal protein uL16 family	rpl10e	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
MMS1_k127_2840266_0	269799.Gmet_1156	3.333e-59	216.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,43T22@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMS1_k127_2840266_1	1131266.ARWQ01000006_gene220	4.306e-21	102.0	COG1938@1|root,arCOG00347@2157|Archaea,41SSA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
MMS1_k127_2840266_2	593750.Metfor_2881	2.721e-19	91.0	arCOG12677@1|root,arCOG12677@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_285640_1	340099.Teth39_2063	8.697e-06	50.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,248YA@186801|Clostridia,42FIC@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
MMS1_k127_285640_0	665950.HMPREF1025_01738	4.479e-06	59.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia	186801|Clostridia	S	Secondary thiamine-phosphate synthase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
MMS1_k127_324909_1	273116.14325521	1.027e-18	95.0	COG1545@1|root,arCOG01287@2157|Archaea,2Y7AV@28890|Euryarchaeota,2427M@183967|Thermoplasmata	183967|Thermoplasmata	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS1_k127_324909_0	273075.Ta0351	1.297e-50	189.0	COG0183@1|root,arCOG01280@2157|Archaea,2Y85P@28890|Euryarchaeota,241YR@183967|Thermoplasmata	183967|Thermoplasmata	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS1_k127_391048_1	1261545.MBE-HAL_2181	5.287e-05	50.0	COG1992@1|root,arCOG00021@2157|Archaea,2XTP7@28890|Euryarchaeota,23SNG@183963|Halobacteria	183963|Halobacteria	H	Transcriptional regulator	thiN2	-	-	ko:K22206	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,ThiP_synth
MMS1_k127_391048_0	436308.Nmar_0495	3.515e-188	598.0	COG0719@1|root,arCOG01715@2157|Archaea,41S5W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
MMS1_k127_414982_1	697281.Mahau_0412	1.708e-16	91.0	COG0167@1|root,COG1149@1|root,COG0167@2|Bacteria,COG1149@2|Bacteria,1TRPI@1239|Firmicutes,24A0Z@186801|Clostridia,42FY6@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM dihydroorotate dehydrogenase family protein	-	-	1.3.1.1,1.3.98.1	ko:K00226,ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4,Fer4_21
MMS1_k127_414982_0	706587.Desti_2244	5.73e-71	246.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,42YBR@68525|delta/epsilon subdivisions,2WU33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
MMS1_k127_426017_8	1450694.BTS2_2929	2.468e-32	138.0	COG2267@1|root,COG2267@2|Bacteria,1TP59@1239|Firmicutes,4HBHV@91061|Bacilli,1ZSJG@1386|Bacillus	91061|Bacilli	I	Ndr family	yugF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS1_k127_426017_4	1121451.DESAM_21130	1.054e-59	216.0	COG0631@1|root,COG0631@2|Bacteria,1R84Y@1224|Proteobacteria,42MVE@68525|delta/epsilon subdivisions,2WK9T@28221|Deltaproteobacteria,2MAS9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
MMS1_k127_426017_3	399549.Msed_1011	4.923e-67	238.0	COG1968@1|root,arCOG04761@2157|Archaea,2XRRZ@28889|Crenarchaeota	28889|Crenarchaeota	I	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
MMS1_k127_426017_1	529709.PYCH_16290	6.5e-111	368.0	COG0470@1|root,arCOG00469@2157|Archaea,2XTC8@28890|Euryarchaeota,2433R@183968|Thermococci	183968|Thermococci	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcS	GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,DNA_pol3_delta2,HTH_3,Intein_splicing,LAGLIDADG_3,Rep_fac_C,RuvB_N
MMS1_k127_426017_2	1209989.TepiRe1_0713	2.834e-76	273.0	COG1109@1|root,COG1109@2|Bacteria,1TS6S@1239|Firmicutes,2491F@186801|Clostridia,42FFK@68295|Thermoanaerobacterales	186801|Clostridia	G	alpha beta alpha domain I	manB	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS1_k127_426017_5	633148.Tagg_1395	3.261e-50	183.0	COG0100@1|root,arCOG04240@2157|Archaea,2XQCR@28889|Crenarchaeota	28889|Crenarchaeota	J	Located on the platform of the 30S subunit	rps11	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
MMS1_k127_426017_7	195522.BD01_2186	1.464e-38	151.0	COG0522@1|root,arCOG04239@2157|Archaea,2XXYX@28890|Euryarchaeota,242UM@183968|Thermococci	183968|Thermococci	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
MMS1_k127_426017_9	272557.APE_1737.1	3.773e-32	132.0	COG0099@1|root,arCOG01722@2157|Archaea,2XQBF@28889|Crenarchaeota	28889|Crenarchaeota	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
MMS1_k127_426017_0	1449080.JQMV01000003_gene890	1.842e-147	481.0	COG1190@1|root,COG1190@2|Bacteria,1WI4Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS1_k127_426017_6	1041930.Mtc_1898	4.823e-48	183.0	COG0095@1|root,arCOG01939@2157|Archaea,2XUJ0@28890|Euryarchaeota	28890|Euryarchaeota	H	COG0095 Lipoate-protein ligase A	lpl	GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
MMS1_k127_426017_11	1163730.FFONT_1312	3.74e-06	53.0	COG0095@1|root,arCOG03837@2157|Archaea,2XRCT@28889|Crenarchaeota	28889|Crenarchaeota	H	Bacterial lipoate protein ligase C-terminus	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	Lip_prot_lig_C
MMS1_k127_426017_10	572546.Arcpr_0880	4.964e-27	116.0	COG0250@1|root,arCOG01920@2157|Archaea,2XWGQ@28890|Euryarchaeota,24688@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
MMS1_k127_428785_0	1041930.Mtc_1305	2.474e-99	334.0	COG1602@1|root,arCOG04269@2157|Archaea,2XTEQ@28890|Euryarchaeota,2NADJ@224756|Methanomicrobia	224756|Methanomicrobia	S	Pfam:DUF650	-	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
MMS1_k127_434828_0	671143.DAMO_0955	6.733e-09	67.0	293FI@1|root,2ZQXY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_524384_2	1122138.AQUZ01000098_gene7764	2.056e-17	87.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
MMS1_k127_524384_0	525909.Afer_0227	1.486e-46	179.0	arCOG03842@1|root,30WW9@2|Bacteria,2IDJ1@201174|Actinobacteria,4CNKU@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function (DUF929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF929
MMS1_k127_524384_1	933801.Ahos_1018	2.418e-34	140.0	COG1226@1|root,arCOG01958@2157|Archaea	2157|Archaea	P	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
MMS1_k127_536700_0	351160.RCIX1696	4.393e-19	103.0	arCOG03561@1|root,arCOG03561@2157|Archaea	2157|Archaea	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_53958_0	273063.STK_10050	2.316e-05	57.0	COG5650@1|root,arCOG03701@2157|Archaea,2XSSS@28889|Crenarchaeota	28889|Crenarchaeota	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_543197_0	56780.SYN_01167	6.304e-78	267.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,43B2Q@68525|delta/epsilon subdivisions,2WK38@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS1_k127_543197_1	439235.Dalk_2835	2.402e-40	155.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42M7J@68525|delta/epsilon subdivisions,2WK1N@28221|Deltaproteobacteria,2MMW5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
MMS1_k127_547220_2	397948.Cmaq_1472	2.491e-14	80.0	COG0463@1|root,arCOG01381@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS1_k127_547220_1	273063.STK_19640	3.45e-24	114.0	COG0500@1|root,arCOG01400@2157|Archaea,2XRAC@28889|Crenarchaeota	28889|Crenarchaeota	Q	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
MMS1_k127_547220_0	272562.CA_C0536	9.027e-65	231.0	COG3967@1|root,COG3967@2|Bacteria,1VA08@1239|Firmicutes,24II3@186801|Clostridia,36J69@31979|Clostridiaceae	186801|Clostridia	M	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K14189	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
MMS1_k127_548218_0	1459636.NTE_01283	8.166e-183	599.0	COG0013@1|root,arCOG01255@2157|Archaea,41SBJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
MMS1_k127_548218_1	65393.PCC7424_3586	1.944e-28	121.0	COG0494@1|root,COG0494@2|Bacteria,1G60V@1117|Cyanobacteria,3KHUQ@43988|Cyanothece	1117|Cyanobacteria	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS1_k127_548218_2	7918.ENSLOCP00000005482	5.298e-17	91.0	KOG4760@1|root,KOG4760@2759|Eukaryota,38GGP@33154|Opisthokonta,3BAJ9@33208|Metazoa,3D522@33213|Bilateria,485T4@7711|Chordata,494EX@7742|Vertebrata,49ZMN@7898|Actinopterygii	33208|Metazoa	L	Exonuclease 5	EXO5	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008409,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0031974,GO:0031981,GO:0033554,GO:0034641,GO:0035312,GO:0036297,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045145,GO:0046483,GO:0046983,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K17815	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exo5
MMS1_k127_550713_0	1121920.AUAU01000017_gene1221	8.191e-41	158.0	COG0605@1|root,COG0605@2|Bacteria	2|Bacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
MMS1_k127_591845_3	591019.Shell_1214	5.346e-20	95.0	COG1042@1|root,arCOG01340@2157|Archaea,2XPR9@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
MMS1_k127_591845_4	573063.Metin_0814	2.216e-16	91.0	COG0420@1|root,arCOG00397@2157|Archaea,2XT7A@28890|Euryarchaeota	28890|Euryarchaeota	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity	mre11	GO:0000217,GO:0000403,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004527,GO:0005488,GO:0005515,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0030145,GO:0033554,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045027,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:1901360,GO:1901363	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
MMS1_k127_591845_0	1183377.Py04_0236	1.89e-75	268.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,242PQ@183968|Thermococci	183968|Thermococci	L	Involved in regulation of DNA replication	cdc6	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA,AAA_16,Cdc6_C
MMS1_k127_591845_2	573063.Metin_0119	6.85e-57	207.0	COG0489@1|root,arCOG00585@2157|Archaea,2XTU2@28890|Euryarchaeota,23QCR@183939|Methanococci	183939|Methanococci	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
MMS1_k127_591845_1	589924.Ferp_0299	2.161e-57	207.0	COG0638@1|root,arCOG00971@2157|Archaea,2XUKA@28890|Euryarchaeota,246RW@183980|Archaeoglobi	183980|Archaeoglobi	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmA	GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
MMS1_k127_605192_0	795797.C497_04282	1.331e-10	68.0	28I58@1|root,2N65W@2157|Archaea,2Y5QR@28890|Euryarchaeota,240Q4@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_605192_1	1196324.A374_13695	0.0001317	49.0	COG2411@1|root,COG2411@2|Bacteria,1V6QX@1239|Firmicutes,4HIQQ@91061|Bacilli	91061|Bacilli	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
MMS1_k127_632722_0	709991.Odosp_0822	1.983e-32	131.0	2BVF9@1|root,32QUP@2|Bacteria,4NS32@976|Bacteroidetes,2FSIF@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_633972_1	192952.MM_0963	1.14e-18	87.0	COG3476@1|root,arCOG04434@2157|Archaea,2XYQD@28890|Euryarchaeota,2NAZX@224756|Methanomicrobia	224756|Methanomicrobia	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
MMS1_k127_633972_2	1006006.Mcup_0824	6.745e-07	57.0	COG0456@1|root,arCOG00833@2157|Archaea,2XRDG@28889|Crenarchaeota	28889|Crenarchaeota	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS1_k127_633972_0	263820.PTO1483	7.225e-37	143.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota	28890|Euryarchaeota	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
MMS1_k127_737993_7	1216007.AOPM01000101_gene695	5.601e-11	73.0	COG2199@1|root,COG2199@2|Bacteria,1R4JZ@1224|Proteobacteria,1RW5E@1236|Gammaproteobacteria,2Q0U1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K20961	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS,PAS_8
MMS1_k127_737993_1	1392486.JIAF01000004_gene1655	9.017e-37	145.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,2FQJ0@200643|Bacteroidia	976|Bacteroidetes	S	ATP cob(I)alamin adenosyltransferase	cobO	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
MMS1_k127_737993_5	1041930.Mtc_0990	4.665e-17	87.0	COG1386@1|root,arCOG02613@2157|Archaea,2XZ7Q@28890|Euryarchaeota,2N9UX@224756|Methanomicrobia	224756|Methanomicrobia	K	Segregation and condensation complex subunit ScpB	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
MMS1_k127_737993_6	269797.Mbar_A0593	2.221e-15	85.0	COG1354@1|root,arCOG02610@2157|Archaea,2XT0N@28890|Euryarchaeota,2N9X2@224756|Methanomicrobia	224756|Methanomicrobia	L	Segregation and condensation protein ScpA	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
MMS1_k127_737993_0	1459636.NTE_03539	1.425e-135	449.0	COG1012@1|root,arCOG01252@2157|Archaea,41T12@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMS1_k127_737993_4	1459636.NTE_03024	3.423e-19	92.0	COG1430@1|root,arCOG03116@2157|Archaea	2157|Archaea	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
MMS1_k127_737993_2	1094980.Mpsy_0887	1.111e-34	144.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,2N97R@224756|Methanomicrobia	224756|Methanomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS1_k127_737993_3	1235813.JCM10003_1282	4.757e-34	141.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,2FMI3@200643|Bacteroidia,4AKW0@815|Bacteroidaceae	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMS1_k127_737993_8	1041930.Mtc_2034	1.793e-07	59.0	COG1371@1|root,arCOG04055@2157|Archaea,2XXRX@28890|Euryarchaeota,2NA1Z@224756|Methanomicrobia	224756|Methanomicrobia	S	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	-	-	-	-	-	-	-	-	-	-	-	Archease
MMS1_k127_793026_2	186497.PF1461	6.086e-112	376.0	COG0252@1|root,arCOG01924@2157|Archaea,2XTN1@28890|Euryarchaeota,2439K@183968|Thermococci	183968|Thermococci	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
MMS1_k127_793026_1	267377.MMP1265	2.439e-127	430.0	COG2511@1|root,arCOG01719@2157|Archaea,2XT73@28890|Euryarchaeota,23QDW@183939|Methanococci	183939|Methanococci	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
MMS1_k127_793026_4	1267535.KB906767_gene4264	3.168e-41	160.0	COG2013@1|root,COG2013@2|Bacteria,3Y2XF@57723|Acidobacteria,2JIE5@204432|Acidobacteriia	204432|Acidobacteriia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
MMS1_k127_793026_5	926567.TheveDRAFT_0774	3.194e-29	123.0	COG0494@1|root,COG0494@2|Bacteria,3TB4E@508458|Synergistetes	508458|Synergistetes	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
MMS1_k127_793026_7	696369.KI912183_gene2778	3.12e-21	102.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,2626V@186807|Peptococcaceae	186801|Clostridia	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
MMS1_k127_793026_0	604354.TSIB_0532	5.599e-163	531.0	COG0532@1|root,arCOG01560@2157|Archaea,2XU09@28890|Euryarchaeota,243N1@183968|Thermococci	183968|Thermococci	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D4,IF-2,Intein_splicing,LAGLIDADG_3
MMS1_k127_793026_3	768679.TTX_0564	2.161e-46	173.0	COG0105@1|root,arCOG04313@2157|Archaea,2XQEV@28889|Crenarchaeota	28889|Crenarchaeota	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
MMS1_k127_793026_6	309803.CTN_0184	1.201e-26	112.0	COG2151@1|root,COG2151@2|Bacteria,2GDA3@200918|Thermotogae	200918|Thermotogae	S	metal-sulfur cluster biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
MMS1_k127_793026_8	877455.Metbo_1615	5.895e-09	70.0	COG3420@1|root,arCOG02497@1|root,arCOG07611@1|root,arCOG02497@2157|Archaea,arCOG02519@2157|Archaea,arCOG07611@2157|Archaea,2Y7RN@28890|Euryarchaeota	28890|Euryarchaeota	P	Domain present in carbohydrate binding proteins and sugar hydrolses	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
MMS1_k127_817413_0	1131730.BAVI_09656	1.13e-43	161.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli,1ZAY4@1386|Bacillus	91061|Bacilli	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	acoA	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
MMS1_k127_817413_1	180281.CPCC7001_1235	0.0007132	48.0	COG1808@1|root,COG1808@2|Bacteria,1GCU0@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
MMS1_k127_84483_1	273063.STK_02260	1.233e-39	154.0	COG0717@1|root,arCOG04048@2157|Archaea,2XQDF@28889|Crenarchaeota	28889|Crenarchaeota	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
MMS1_k127_84483_5	410358.Mlab_0758	1.929e-05	51.0	COG1873@1|root,arCOG02155@2157|Archaea,2XZ54@28890|Euryarchaeota,2N9Y7@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
MMS1_k127_84483_4	1094980.Mpsy_0954	1.003e-17	95.0	COG1676@1|root,arCOG01701@2157|Archaea,2XTKB@28890|Euryarchaeota,2N92W@224756|Methanomicrobia	224756|Methanomicrobia	J	sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp	endA	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
MMS1_k127_84483_3	1382306.JNIM01000001_gene724	5.864e-18	95.0	COG0392@1|root,COG0392@2|Bacteria,2G6EN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
MMS1_k127_84483_2	1220534.B655_1691	4.058e-36	147.0	COG1798@1|root,arCOG04161@2157|Archaea,2XV63@28890|Euryarchaeota,23NX5@183925|Methanobacteria	183925|Methanobacteria	J	S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis	dphB	-	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	-	TP_methylase
MMS1_k127_84483_0	1343739.PAP_10275	6.269e-107	356.0	COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,242UY@183968|Thermococci	183968|Thermococci	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Intein_splicing,LAGLIDADG_3,Rad51
MMS1_k127_879036_2	1236976.JCM16418_1531	6.389e-31	128.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,26Y5Y@186822|Paenibacillaceae	91061|Bacilli	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	dfrA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
MMS1_k127_879036_1	1121396.KB893101_gene475	8.132e-122	398.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,42PY3@68525|delta/epsilon subdivisions,2WV23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	-	-	-	-	-	-	-	-	-	-	Thymidylat_synt
MMS1_k127_879036_0	1410632.JHWW01000011_gene2362	9.275e-132	435.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,27I79@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
MMS1_k127_879036_3	693661.Arcve_0508	2.258e-24	109.0	COG2433@1|root,arCOG04219@2157|Archaea,2XT3D@28890|Euryarchaeota,245WA@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function (DUF460)	-	-	-	ko:K09150	-	-	-	-	ko00000	-	-	-	DUF460
MMS1_k127_895571_1	552811.Dehly_0623	6.234e-55	206.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
MMS1_k127_895571_0	706587.Desti_1918	4.111e-176	557.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	bamH	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K05587,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_2080	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
MMS1_k127_902253_0	70601.3257481	1.696e-207	683.0	COG0060@1|root,arCOG00807@2157|Archaea,2XTIX@28890|Euryarchaeota,242NA@183968|Thermococci	183968|Thermococci	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
MMS1_k127_911488_2	267377.MMP0522	9.172e-10	68.0	COG1361@1|root,arCOG02079@2157|Archaea,2XTX8@28890|Euryarchaeota,23QFC@183939|Methanococci	183939|Methanococci	M	COG1361 S-layer domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_911488_0	1094980.Mpsy_1357	4.754e-89	309.0	COG0577@1|root,arCOG02312@2157|Archaea,2XUEE@28890|Euryarchaeota,2NAGX@224756|Methanomicrobia	224756|Methanomicrobia	P	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS1_k127_911488_1	1295642.H839_16738	4.065e-53	204.0	COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4H9YA@91061|Bacilli,1WEW9@129337|Geobacillus	91061|Bacilli	P	Fungal trichothecene efflux pump (TRI12)	yusP	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_913054_3	485913.Krac_10289	5.643e-19	98.0	COG2933@1|root,COG2933@2|Bacteria,2G6K6@200795|Chloroflexi	200795|Chloroflexi	J	FtsJ-like methyltransferase	-	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,THUMP
MMS1_k127_913054_2	273075.Ta0008	2.788e-54	213.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota,241UP@183967|Thermoplasmata	183967|Thermoplasmata	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
MMS1_k127_913054_5	263820.PTO0494	1.593e-14	75.0	COG0636@1|root,arCOG02455@2157|Archaea,2Y1B9@28890|Euryarchaeota,242DV@183967|Thermoplasmata	183967|Thermoplasmata	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
MMS1_k127_913054_7	655812.HMPREF0061_1480	1.131e-07	64.0	COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,4HD5K@91061|Bacilli,27ERF@186827|Aerococcaceae	91061|Bacilli	C	ATP synthase (C/AC39) subunit	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
MMS1_k127_913054_4	439481.Aboo_1263	3.157e-15	80.0	COG1436@1|root,arCOG04102@2157|Archaea,2Y1TB@28890|Euryarchaeota,3F3EN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
MMS1_k127_913054_0	1408322.JHYK01000009_gene2307	3.036e-216	685.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,27IS3@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
MMS1_k127_913054_1	673860.AciM339_1305	1.488e-102	342.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,3F2FK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
MMS1_k127_937556_4	565033.GACE_1465	5.859e-54	200.0	COG0086@1|root,arCOG04257@2157|Archaea,2XTBZ@28890|Euryarchaeota,245UU@183980|Archaeoglobi	183980|Archaeoglobi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMS1_k127_937556_1	644281.MFS40622_1660	6.691e-80	278.0	COG0086@1|root,arCOG04256@2157|Archaea,2XTJ6@28890|Euryarchaeota,23Q5X@183939|Methanococci	183939|Methanococci	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	-	2.7.7.6	ko:K03042	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_5
MMS1_k127_937556_7	572546.Arcpr_0994	9.444e-17	81.0	COG1958@1|root,arCOG00998@2157|Archaea,2XZTF@28890|Euryarchaeota,246DE@183980|Archaeoglobi	183980|Archaeoglobi	K	Belongs to the snRNP Sm proteins family	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
MMS1_k127_937556_6	273116.14324887	5.407e-22	100.0	COG0393@1|root,arCOG02287@2157|Archaea,2XYRF@28890|Euryarchaeota,2429W@183967|Thermoplasmata	183967|Thermoplasmata	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
MMS1_k127_937556_5	1041930.Mtc_1209	6.087e-35	137.0	COG0393@1|root,arCOG02287@2157|Archaea,2XYRF@28890|Euryarchaeota,2NAUZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
MMS1_k127_937556_3	273063.STK_09040	8.942e-67	243.0	COG0577@1|root,arCOG02312@2157|Archaea,2XQ0N@28889|Crenarchaeota	28889|Crenarchaeota	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS1_k127_937556_8	671065.MetMK1DRAFT_00010760	0.0003281	53.0	COG1361@1|root,arCOG02089@2157|Archaea,2XR0S@28889|Crenarchaeota	28889|Crenarchaeota	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_937556_2	484019.THA_432	2.31e-68	240.0	COG1136@1|root,COG1136@2|Bacteria,2GCNV@200918|Thermotogae	200918|Thermotogae	P	PFAM ABC transporter	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS1_k127_937556_0	273075.Ta0228	6.863e-86	291.0	COG0412@1|root,arCOG01659@2157|Archaea,2Y6XB@28890|Euryarchaeota,2422E@183967|Thermoplasmata	183967|Thermoplasmata	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS1_k127_950106_4	467661.RKLH11_646	3.119e-05	51.0	2DX1G@1|root,342Z1@2|Bacteria,1NYIP@1224|Proteobacteria,2USYV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_950106_3	1355368.JART01000020_gene1168	4.394e-17	94.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2YMFD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Heme d1 biosynthesis protein NirJ	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
MMS1_k127_950106_1	589924.Ferp_2110	2.309e-58	226.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,245QA@183980|Archaeoglobi	183980|Archaeoglobi	G	PFAM Pyruvate phosphate dikinase, PEP	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS1_k127_950106_2	123214.PERMA_1687	5.485e-27	115.0	COG1586@1|root,COG1586@2|Bacteria,2G4Q4@200783|Aquificae	200783|Aquificae	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
MMS1_k127_950106_0	1041930.Mtc_2490	3.097e-152	505.0	COG1204@1|root,arCOG00553@2157|Archaea,2XSV4@28890|Euryarchaeota,2N9A8@224756|Methanomicrobia	224756|Methanomicrobia	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
MMS1_k127_952924_0	273116.14325210	8.979e-05	54.0	COG5650@1|root,arCOG03701@2157|Archaea,2Y3VN@28890|Euryarchaeota,2429C@183967|Thermoplasmata	183967|Thermoplasmata	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_95698_2	342949.PNA2_1518	2.509e-21	107.0	COG1041@1|root,arCOG00047@2157|Archaea,2Y2EJ@28890|Euryarchaeota,2432J@183968|Thermococci	183968|Thermococci	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
MMS1_k127_95698_3	399549.Msed_0771	1.111e-07	55.0	COG0517@1|root,arCOG00606@2157|Archaea,2XR8I@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMS1_k127_95698_1	273063.STK_24330	4.106e-128	415.0	COG1013@1|root,arCOG01599@2157|Archaea,2XPQG@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
MMS1_k127_95698_0	273063.STK_24350	5.472e-253	794.0	COG0674@1|root,arCOG01606@2157|Archaea	2157|Archaea	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	korA	-	1.2.7.1,1.2.7.11,1.2.7.3	ko:K00169,ko:K00174	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00307,M00374,M00620	R01196,R01197,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
MMS1_k127_959838_0	439235.Dalk_4614	2.105e-17	89.0	COG1196@1|root,COG1196@2|Bacteria,1R09G@1224|Proteobacteria,43CSI@68525|delta/epsilon subdivisions,2X805@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	DNA N-6-adenine-methyltransferase (Dam)	-	-	-	-	-	-	-	-	-	-	-	-	Dam
MMS1_k127_988100_2	391623.TERMP_02121	2.75e-18	100.0	COG1287@1|root,arCOG02044@2157|Archaea,2XU59@28890|Euryarchaeota,242T3@183968|Thermococci	183968|Thermococci	M	Oligosaccharyl transferase, STT3 subunit	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
MMS1_k127_988100_1	868131.MSWAN_2343	4.832e-27	126.0	COG0750@1|root,arCOG04064@2157|Archaea,2XSZP@28890|Euryarchaeota,23NP1@183925|Methanobacteria	183925|Methanobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
MMS1_k127_988100_0	647113.Metok_0824	4.507e-33	134.0	COG0575@1|root,arCOG04106@2157|Archaea,2XWNR@28890|Euryarchaeota,23QZ6@183939|Methanococci	183939|Methanococci	I	Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids	carS	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
## 576 queries scanned
## Total time (seconds): 102.24677038192749
## Rate: 5.63 q/s