## Fri Oct 18 03:00:37 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/MMS1_bin.61.fa -m mmseqs --itype genome -o MMS1_bin.61 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/MMS1_bin.61 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
MMS1_k127_1037810_3	1172180.KB911776_gene751	5.109e-65	246.0	2EKY7@1|root,33EMR@2|Bacteria,2IBEG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1037810_8	1121877.JQKF01000112_gene1255	2.11e-19	92.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1037810_4	1449976.KALB_79	8.593e-44	171.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K15257	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Methyltransf_23,Methyltransf_31,Methyltransf_9
MMS1_k127_1037810_0	1463856.JOHY01000029_gene2697	3.216e-113	385.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
MMS1_k127_1037810_2	1197130.BAFM01000008_gene1583	1.397e-65	236.0	COG0119@1|root,arCOG02092@2157|Archaea,2XUF5@28890|Euryarchaeota,23U7Z@183963|Halobacteria	183963|Halobacteria	E	COG0119 Isopropylmalate homocitrate citramalate synthases	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
MMS1_k127_1037810_7	1144310.PMI07_001616	9.059e-29	125.0	COG2186@1|root,COG2186@2|Bacteria,1MV83@1224|Proteobacteria,2UDPS@28211|Alphaproteobacteria,4B9ID@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS1_k127_1037810_1	525909.Afer_0279	1.718e-74	255.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1037810_6	526225.Gobs_0606	1.092e-34	143.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,4EVSI@85013|Frankiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS1_k127_1037810_5	1289387.AUKW01000001_gene5354	4.155e-37	145.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class v	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS1_k127_1047074_2	1437605.BACT_0926	4.837e-17	83.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CZKG@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
MMS1_k127_1047074_0	1343740.M271_03650	8.151e-91	321.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
MMS1_k127_1047074_1	1313172.YM304_23990	7.259e-36	149.0	COG2267@1|root,COG2267@2|Bacteria,2GYP0@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
MMS1_k127_1047074_3	1123251.ATWM01000007_gene2430	1.602e-06	51.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4FF0S@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
MMS1_k127_1055911_0	469383.Cwoe_5611	2.091e-317	1004.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,2GKBW@201174|Actinobacteria,4CPFA@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
MMS1_k127_1055911_2	1449080.JQMV01000003_gene2114	1.071e-40	159.0	COG3437@1|root,COG3437@2|Bacteria,1WJ00@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Metal dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD,HD_5,PAS_3,PAS_4,PAS_8
MMS1_k127_1055911_1	1382303.JPOM01000001_gene100	2.455e-104	345.0	COG1024@1|root,COG1024@2|Bacteria,1MVPQ@1224|Proteobacteria,2TTJ4@28211|Alphaproteobacteria,2KG1I@204458|Caulobacterales	204458|Caulobacterales	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS1_k127_1055911_4	1229780.BN381_10276	2.367e-17	95.0	COG1466@1|root,COG1466@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	holA	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
MMS1_k127_1055911_3	525909.Afer_1304	7.466e-20	91.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4CNF4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
MMS1_k127_1071397_3	479432.Sros_1747	3.064e-55	210.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4EGXF@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
MMS1_k127_1071397_5	543632.JOJL01000067_gene1393	1.096e-33	139.0	2B8ZY@1|root,322AK@2|Bacteria,2H6NN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1071397_2	1380390.JIAT01000009_gene1049	1.575e-90	307.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4CQ7M@84995|Rubrobacteria	84995|Rubrobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS1_k127_1071397_4	211114.JOEF01000016_gene3812	1.022e-34	140.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4DZG7@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
MMS1_k127_1071397_0	1313172.YM304_20840	3.404e-174	558.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CMW7@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
MMS1_k127_1071397_1	525909.Afer_1659	2.522e-118	386.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CNB6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the argininosuccinate synthase family. Type	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
MMS1_k127_1072288_0	525909.Afer_1286	3.162e-199	629.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CMRX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS1_k127_1072288_1	1121877.JQKF01000022_gene2291	2.655e-41	164.0	COG2365@1|root,COG2365@2|Bacteria,2HGPQ@201174|Actinobacteria,4CNS5@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
MMS1_k127_1074524_5	1123023.JIAI01000021_gene2406	4.425e-34	148.0	COG2508@1|root,COG2508@2|Bacteria,2IEDJ@201174|Actinobacteria	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
MMS1_k127_1074524_1	1123024.AUII01000011_gene4470	2.934e-147	483.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4DZY3@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
MMS1_k127_1074524_4	926560.KE387023_gene1789	1.631e-67	242.0	COG0604@1|root,COG0604@2|Bacteria,1WMA1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS1_k127_1074524_6	1229780.BN381_250082	0.000611	46.0	COG0535@1|root,COG0535@2|Bacteria,2GQQT@201174|Actinobacteria	201174|Actinobacteria	S	Mycofactocin system	mftB	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1074524_2	1229780.BN381_250081	4.073e-132	433.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	pqqE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
MMS1_k127_1074524_3	1157638.KB892174_gene329	6.661e-108	374.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GMB6@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	NAD_binding_8,Oxidored_FMN,Pyr_redox,Pyr_redox_2
MMS1_k127_1074524_0	1157638.KB892174_gene328	1.97e-232	736.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	FAD_oxidored,Oxidored_FMN,Pyr_redox_2
MMS1_k127_1079986_0	1379698.RBG1_1C00001G0808	2.367e-99	343.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NQNK@2323|unclassified Bacteria	2|Bacteria	EU	Peptidase S9 prolyl oligopeptidase active site	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
MMS1_k127_1080734_2	1313172.YM304_33370	1.659e-103	348.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CNNX@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
MMS1_k127_1080734_3	1380356.JNIK01000019_gene406	2.203e-94	319.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4ERZB@85013|Frankiales	201174|Actinobacteria	S	PFAM ATPase associated with various cellular activities AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
MMS1_k127_1080734_1	525909.Afer_1568	1.127e-107	355.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CMQN@84992|Acidimicrobiia	84992|Acidimicrobiia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMS1_k127_1080734_0	1121877.JQKF01000003_gene1486	7.851e-147	469.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CMWW@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS1_k127_109008_3	1120934.KB894426_gene3600	8.246e-92	317.0	COG0530@1|root,COG0530@2|Bacteria,2GP6H@201174|Actinobacteria,4E18G@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
MMS1_k127_109008_8	479432.Sros_1705	1.495e-32	136.0	COG1102@1|root,COG1102@2|Bacteria,2I8J3@201174|Actinobacteria,4EJ4B@85012|Streptosporangiales	201174|Actinobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
MMS1_k127_109008_5	1123024.AUII01000052_gene3915	3.906e-75	259.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4E0T5@85010|Pseudonocardiales	201174|Actinobacteria	KP	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
MMS1_k127_109008_7	1121877.JQKF01000014_gene43	2.361e-60	216.0	COG0671@1|root,COG0671@2|Bacteria,2GNBT@201174|Actinobacteria,4CNQX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
MMS1_k127_109008_2	1394178.AWOO02000033_gene8472	1.9e-104	345.0	COG2872@1|root,COG2872@2|Bacteria,2I8P6@201174|Actinobacteria,4ENHQ@85012|Streptosporangiales	201174|Actinobacteria	S	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
MMS1_k127_109008_0	326424.FRAAL3996	6.555e-216	687.0	COG0477@1|root,COG0477@2|Bacteria,2GJSC@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_109008_1	290399.Arth_1074	4.073e-135	444.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
MMS1_k127_109008_11	1173264.KI913949_gene541	5.65e-09	63.0	COG0484@1|root,COG0484@2|Bacteria,1G5UK@1117|Cyanobacteria,1H9H6@1150|Oscillatoriales	1117|Cyanobacteria	O	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_2
MMS1_k127_109008_10	1211815.CBYP010000063_gene1880	1.064e-21	96.0	2EK1R@1|root,33DS7@2|Bacteria,2GWKM@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
MMS1_k127_109008_9	1121924.ATWH01000005_gene2655	8.289e-23	115.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,Big_3_5,Calx-beta,CarboxypepD_reg,DUF11,DUF3616,DUF3859,Prenyltrans,SLH
MMS1_k127_109008_4	635013.TherJR_2186	1.726e-81	284.0	COG3621@1|root,COG3621@2|Bacteria,1UYFU@1239|Firmicutes,25DW4@186801|Clostridia	186801|Clostridia	S	PFAM Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
MMS1_k127_109008_6	1158050.KB895453_gene1012	4.435e-65	227.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria	201174|Actinobacteria	IQ	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS1_k127_1092701_0	1229780.BN381_40071	1.85e-128	420.0	COG1625@1|root,COG1625@2|Bacteria,2H3RR@201174|Actinobacteria	201174|Actinobacteria	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
MMS1_k127_1092701_1	1229780.BN381_40070	1.363e-121	400.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,3UW8T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS1_k127_1092701_2	1121877.JQKF01000026_gene2440	6.037e-50	186.0	COG0204@1|root,COG0204@2|Bacteria,2HG51@201174|Actinobacteria,4CN6X@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS1_k127_1100698_1	994479.GL877878_gene3249	9.793e-26	112.0	2DBRY@1|root,2ZANS@2|Bacteria,2I81X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1100698_0	1524467.IV04_19395	3.901e-79	278.0	COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,1RMXR@1236|Gammaproteobacteria,4002J@613|Serratia	1236|Gammaproteobacteria	EGP	Sugar (and other) transporter	ygaY	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS1_k127_1100698_2	1206726.BAFV01000123_gene6318	3.484e-19	94.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,4FU6N@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
MMS1_k127_11015_2	1121877.JQKF01000009_gene572	2.148e-137	445.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4CMPU@84992|Acidimicrobiia	84992|Acidimicrobiia	CP	protein synonym multiple resistance and pH homeostasis protein A	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
MMS1_k127_11015_5	1121877.JQKF01000009_gene573	1.875e-35	144.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CN4N@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMS1_k127_11015_4	1121877.JQKF01000009_gene574	3.334e-37	150.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4CN8Y@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
MMS1_k127_11015_3	1121877.JQKF01000009_gene575	4.369e-114	370.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4CMPP@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
MMS1_k127_11015_1	1121877.JQKF01000009_gene576	8.625e-179	569.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4CMTV@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
MMS1_k127_11015_0	1229780.BN381_160007	9.119e-186	612.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,3UWBF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMS1_k127_11015_6	1121877.JQKF01000009_gene578	0.0008741	42.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4CMQ2@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S
MMS1_k127_1111641_2	351607.Acel_1463	1.538e-20	105.0	COG1835@1|root,COG1835@2|Bacteria,2GMY0@201174|Actinobacteria,4ET71@85013|Frankiales	201174|Actinobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1111641_0	1313172.YM304_37400	3.929e-98	332.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4CMXY@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS1_k127_1111641_1	1229780.BN381_90077	2.912e-26	121.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMS1_k127_1111641_3	525909.Afer_0472	6.868e-19	93.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4CNKK@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMS1_k127_1112187_0	1068978.AMETH_4017	1.312e-251	802.0	COG0439@1|root,COG4770@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4770@2|Bacteria,COG4799@2|Bacteria,2GIZP@201174|Actinobacteria,4EE6U@85010|Pseudonocardiales	201174|Actinobacteria	I	Pfam:CPSase_L_chain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
MMS1_k127_1112187_1	1120948.KB903218_gene1996	4.006e-163	522.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E27I@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_1114218_3	457425.XNR_0328	8.783e-90	306.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
MMS1_k127_1114218_1	525909.Afer_0163	1.285e-141	460.0	COG0446@1|root,COG0446@2|Bacteria,2IB5R@201174|Actinobacteria	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS1_k127_1114218_2	1313172.YM304_12950	6.634e-118	393.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMRN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
MMS1_k127_1114218_0	479434.Sthe_0360	1.518e-239	751.0	COG0318@1|root,COG0318@2|Bacteria,2G5SX@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_1114218_4	1394178.AWOO02000053_gene8146	2.062e-75	265.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4EFV0@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
MMS1_k127_1114218_6	1121877.JQKF01000064_gene2334	4.129e-31	132.0	COG2267@1|root,COG2267@2|Bacteria,2I5RV@201174|Actinobacteria,4CNT3@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMS1_k127_1114218_5	1246995.AFR_37970	1.212e-62	224.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4DAGY@85008|Micromonosporales	201174|Actinobacteria	C	dehydrogenase, E1 component	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
MMS1_k127_1124121_3	1121877.JQKF01000024_gene2410	6.745e-46	171.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CNMG@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
MMS1_k127_1124121_0	1121877.JQKF01000024_gene2409	2.517e-119	390.0	COG1622@1|root,COG1622@2|Bacteria,2HGN7@201174|Actinobacteria,4CNP4@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
MMS1_k127_1124121_2	525909.Afer_1709	3.264e-84	284.0	arCOG07408@1|root,2ZWPP@2|Bacteria,2HGM2@201174|Actinobacteria,4CNJ3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1124121_5	1121468.AUBR01000094_gene767	1.848e-15	84.0	COG0526@1|root,COG0526@2|Bacteria,1V7JP@1239|Firmicutes,25ET7@186801|Clostridia,42JE2@68295|Thermoanaerobacterales	186801|Clostridia	CO	Thioredoxin-like	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	AhpC-TSA,Redoxin
MMS1_k127_1124121_1	525909.Afer_1711	3.903e-116	381.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4CMQ7@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
MMS1_k127_1124121_4	58123.JOFJ01000001_gene3057	1.024e-31	134.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4EGJ2@85012|Streptosporangiales	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMS1_k127_1141025_5	656024.FsymDg_0417	4.418e-14	80.0	COG0694@1|root,COG2146@1|root,COG0694@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	ko:K05710,ko:K13628	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko03016	-	-	-	NifU,Rieske
MMS1_k127_1141025_4	1108045.GORHZ_135_00750	3.38e-14	81.0	2E9I6@1|root,333R7@2|Bacteria,2H0FR@201174|Actinobacteria,4GGAS@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1141025_1	106370.Francci3_1074	3.948e-67	245.0	COG0457@1|root,COG0457@2|Bacteria,2GNKM@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1141025_6	1150599.MPHLEI_15411	2.429e-08	57.0	28RVZ@1|root,2ZE88@2|Bacteria,2GQTU@201174|Actinobacteria,23BAA@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1141025_7	1123024.AUII01000037_gene4369	7.977e-05	49.0	COG0680@1|root,COG0680@2|Bacteria,2I1SR@201174|Actinobacteria,4E7VW@85010|Pseudonocardiales	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
MMS1_k127_1141025_3	1123024.AUII01000037_gene4369	5.704e-55	198.0	COG0680@1|root,COG0680@2|Bacteria,2I1SR@201174|Actinobacteria,4E7VW@85010|Pseudonocardiales	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
MMS1_k127_1141025_0	1122247.C731_1611	5.131e-311	957.0	COG0374@1|root,COG0374@2|Bacteria,2GKQY@201174|Actinobacteria,236A3@1762|Mycobacteriaceae	201174|Actinobacteria	C	Ni,Fe-hydrogenase I large subunit	hybC	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
MMS1_k127_1141025_2	1184609.KILIM_105_00070	2.654e-59	205.0	COG1740@1|root,COG1740@2|Bacteria,2GKF2@201174|Actinobacteria	201174|Actinobacteria	C	Small subunit	hoxK	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
MMS1_k127_1145433_5	1385519.N801_08655	0.0002404	53.0	2EIY5@1|root,33CPB@2|Bacteria,2I391@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1145433_3	345341.KUTG_07898	1.692e-41	159.0	COG4385@1|root,COG4385@2|Bacteria,2HG1T@201174|Actinobacteria,4E3QS@85010|Pseudonocardiales	201174|Actinobacteria	S	Phage tail protein (Tail_P2_I)	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
MMS1_k127_1145433_0	1133850.SHJG_2419	1.976e-218	695.0	COG3299@1|root,COG3299@2|Bacteria,2GM5C@201174|Actinobacteria	201174|Actinobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
MMS1_k127_1145433_2	1463845.JOIG01000009_gene3137	3.291e-45	167.0	COG3628@1|root,COG3628@2|Bacteria,2IFJ6@201174|Actinobacteria	201174|Actinobacteria	S	GPW gp25 family protein	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
MMS1_k127_1145433_1	479431.Namu_1906	2.523e-69	258.0	COG3500@1|root,COG3501@1|root,COG3500@2|Bacteria,COG3501@2|Bacteria,2GP13@201174|Actinobacteria,4ET67@85013|Frankiales	201174|Actinobacteria	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
MMS1_k127_1145433_4	1463845.JOIG01000009_gene3135	6.979e-40	152.0	COG1652@1|root,COG1652@2|Bacteria,2IAAU@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Peptidoglycan-binding	-	-	-	-	-	-	-	-	-	-	-	-	LysM
MMS1_k127_1145867_2	1123251.ATWM01000004_gene1762	9.009e-12	78.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria,4FI91@85021|Intrasporangiaceae	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
MMS1_k127_1145867_0	1246995.AFR_04305	1.106e-62	234.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1145867_1	859657.RPSI07_mp0509	1.79e-28	124.0	COG1239@1|root,COG1240@1|root,COG1239@2|Bacteria,COG1240@2|Bacteria,1MVD4@1224|Proteobacteria,2VJ2U@28216|Betaproteobacteria,1K2XC@119060|Burkholderiaceae	28216|Betaproteobacteria	H	magnesium chelatase	bchI	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase,VWA_2
MMS1_k127_1151808_8	31964.CMS1959	9.105e-12	68.0	COG0847@1|root,COG0847@2|Bacteria,2I2KI@201174|Actinobacteria,4FN64@85023|Microbacteriaceae	201174|Actinobacteria	L	Exonuclease	dnaQ2	-	2.7.7.7	ko:K02337,ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
MMS1_k127_1151808_1	1068978.AMETH_1911	1.393e-162	521.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,4DXGA@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS1_k127_1151808_0	1211815.CBYP010000068_gene194	3.814e-166	539.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_1151808_6	1206741.BAFX01000061_gene5166	1.23e-45	177.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4FUPK@85025|Nocardiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
MMS1_k127_1151808_7	1051632.TPY_1878	2.254e-27	118.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,24HA8@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790,ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
MMS1_k127_1151808_4	477641.MODMU_4726	1.255e-70	250.0	COG0382@1|root,COG0382@2|Bacteria,2GJ6P@201174|Actinobacteria,4EV3I@85013|Frankiales	201174|Actinobacteria	H	UbiA prenyltransferase family	ubiA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016763,GO:0031224,GO:0031226,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046872,GO:0052636,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.2.45	ko:K14136	-	-	R10095	RC00005	ko00000,ko01000,ko01006	-	-	-	UbiA
MMS1_k127_1151808_2	1120950.KB892742_gene3045	4.906e-160	518.0	COG0277@1|root,COG0277@2|Bacteria,2HZ5X@201174|Actinobacteria,4DNVZ@85009|Propionibacteriales	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	1.1.98.3	ko:K16653	-	-	-	-	ko00000,ko01000	-	-	-	ALO,FAD_binding_4
MMS1_k127_1151808_5	1463909.KL585947_gene5387	1.096e-52	195.0	COG0300@1|root,COG0300@2|Bacteria,2GNPI@201174|Actinobacteria	201174|Actinobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	phbB	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
MMS1_k127_1151808_3	1246995.AFR_04305	6.214e-73	251.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1152058_6	298655.KI912266_gene2064	7.386e-25	108.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4EV2M@85013|Frankiales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
MMS1_k127_1152058_1	1380347.JNII01000006_gene1790	6.667e-108	359.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4EUPQ@85013|Frankiales	201174|Actinobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
MMS1_k127_1152058_0	298655.KI912266_gene2062	2.337e-113	371.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4ES1M@85013|Frankiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	atrC	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
MMS1_k127_1152058_7	1536772.R70723_02480	4.609e-21	104.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,26QCB@186822|Paenibacillaceae	91061|Bacilli	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	mtnU	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
MMS1_k127_1152058_5	1108045.GORHZ_135_00840	4.385e-41	158.0	COG4454@1|root,COG4454@2|Bacteria,2I9JP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SoxE
MMS1_k127_1152058_8	1172185.KB911517_gene1693	4.423e-12	69.0	COG3462@1|root,COG3462@2|Bacteria,2GWIQ@201174|Actinobacteria,4G4YD@85025|Nocardiaceae	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
MMS1_k127_1152058_4	997346.HMPREF9374_2544	2.934e-45	173.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,27BV3@186824|Thermoactinomycetaceae	91061|Bacilli	FJ	MafB19-like deaminase	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
MMS1_k127_1152058_2	589865.DaAHT2_0079	4.471e-65	230.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2WMVB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS1_k127_1152058_3	285535.JOEY01000007_gene8350	1.23e-53	203.0	COG0577@1|root,COG0577@2|Bacteria,2GMH5@201174|Actinobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS1_k127_1154966_4	525909.Afer_0580	2.925e-32	139.0	COG0392@1|root,COG0392@2|Bacteria,2HGNQ@201174|Actinobacteria,4CNQG@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMS1_k127_1154966_0	234267.Acid_7254	1.956e-219	697.0	COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria	57723|Acidobacteria	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
MMS1_k127_1154966_2	525909.Afer_0577	6.448e-53	200.0	COG3336@1|root,COG3336@2|Bacteria,2HG9Q@201174|Actinobacteria,4CN83@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
MMS1_k127_1154966_3	1121019.AUMN01000002_gene272	4.617e-38	163.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,1W8EM@1268|Micrococcaceae	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
MMS1_k127_1154966_1	58344.JOEL01000003_gene1434	2.262e-82	278.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria	201174|Actinobacteria	Q	Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS1_k127_1158096_2	1229780.BN381_80287	1.361e-20	96.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,3UW7X@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Type II/IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
MMS1_k127_1158096_0	1120950.KB892708_gene4199	3.963e-205	653.0	COG0477@1|root,COG0477@2|Bacteria,2GJSC@201174|Actinobacteria,4DN0Z@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
MMS1_k127_1158096_1	1211815.CBYP010000050_gene580	6.645e-65	233.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4ESQS@85013|Frankiales	201174|Actinobacteria	S	beta-lactamase domain protein	pksB_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS1_k127_1158219_5	1380393.JHVP01000012_gene2773	8.328e-22	100.0	COG4339@1|root,COG4339@2|Bacteria,2IQ60@201174|Actinobacteria,4ETC4@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF4031)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031
MMS1_k127_1158219_1	1121877.JQKF01000002_gene1662	2.937e-107	352.0	COG1018@1|root,COG1018@2|Bacteria,2HGIT@201174|Actinobacteria,4CNH9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
MMS1_k127_1158219_4	1229780.BN381_140045	4.906e-22	97.0	2ES7R@1|root,33JSG@2|Bacteria,2I1DU@201174|Actinobacteria,3UXPZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1158219_3	1229780.BN381_140046	1.453e-64	242.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,3UWMB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	GIY-YIG type nucleases (URI domain)	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
MMS1_k127_1158219_2	1068978.AMETH_5128	4.898e-85	293.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4DYFX@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
MMS1_k127_1158219_0	1504319.GM45_1635	1.372e-156	511.0	COG0001@1|root,COG0001@2|Bacteria,2HBVS@201174|Actinobacteria,3UXSC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS1_k127_1158219_6	1229780.BN381_170006	1.529e-06	50.0	2CC1Y@1|root,32YV9@2|Bacteria,2HGFB@201174|Actinobacteria,3UXMX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Transcription factor WhiB	-	-	-	-	-	-	-	-	-	-	-	-	Whib
MMS1_k127_1163573_0	525909.Afer_0396	1.068e-205	642.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CMSE@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMS1_k127_1163573_3	525909.Afer_0397	2.425e-45	166.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4CN6W@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
MMS1_k127_1163573_1	1121877.JQKF01000009_gene548	2.052e-80	275.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CMZP@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
MMS1_k127_1163573_2	1229780.BN381_450096	3.962e-50	183.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,3UWGH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
MMS1_k127_1167334_3	512565.AMIS_14200	4.376e-36	146.0	COG3336@1|root,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4D95Z@85008|Micromonosporales	201174|Actinobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG
MMS1_k127_1167334_2	1278073.MYSTI_07208	2.124e-51	186.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,2YV5F@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS1_k127_1167334_1	1121877.JQKF01000069_gene1265	4.741e-79	272.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4CMYW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS1_k127_1167334_0	1348338.ADILRU_0468	2.326e-95	318.0	COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,2IA5J@201174|Actinobacteria,4FQY1@85023|Microbacteriaceae	201174|Actinobacteria	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
MMS1_k127_1170456_5	1206735.BAGG01000035_gene1622	2.129e-09	64.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,4FU6N@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
MMS1_k127_1170456_3	1122609.AUGT01000003_gene2171	3.468e-38	150.0	COG0454@1|root,COG0456@2|Bacteria,2GQGN@201174|Actinobacteria,4DS9Y@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS1_k127_1170456_1	1122138.AQUZ01000067_gene4316	1.877e-136	444.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4DPBM@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMS1_k127_1170456_0	1333998.M2A_1597	8.754e-188	600.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TRRZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	MA20_06755	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS1_k127_1170456_2	1380390.JIAT01000011_gene2397	4.03e-128	424.0	COG4097@1|root,COG4097@2|Bacteria,2GKWX@201174|Actinobacteria,4CRXT@84995|Rubrobacteria	84995|Rubrobacteria	P	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
MMS1_k127_1170456_4	436229.JOEH01000011_gene5482	4.725e-11	72.0	COG3976@1|root,COG3976@2|Bacteria,2GTTI@201174|Actinobacteria,2NJ3B@228398|Streptacidiphilus	201174|Actinobacteria	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
MMS1_k127_1180969_3	1463856.JOHY01000039_gene1594	5.246e-21	106.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	oppA	GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0022857,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043295,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072341,GO:1900750,GO:1901681,GO:1904680	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS1_k127_1180969_2	1121877.JQKF01000028_gene2137	1.33e-23	102.0	COG1314@1|root,COG1314@2|Bacteria,2HGDT@201174|Actinobacteria,4CNCC@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
MMS1_k127_1180969_1	1313172.YM304_21690	5.428e-88	300.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CMZ0@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
MMS1_k127_1180969_0	525909.Afer_0850	2.938e-105	349.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CMV0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
MMS1_k127_1187420_0	525909.Afer_1903	0.0	1161.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CMPF@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS1_k127_1187420_3	1121877.JQKF01000035_gene1970	1.018e-74	264.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CMZ7@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Polyprenyl synthetase	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS1_k127_1187420_5	1121877.JQKF01000003_gene1563	7.892e-47	173.0	COG2246@1|root,COG2246@2|Bacteria,2HGRJ@201174|Actinobacteria,4CNUB@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
MMS1_k127_1187420_2	1121877.JQKF01000003_gene1564	2.146e-120	392.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4CMRR@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Thioesterase-like superfamily	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
MMS1_k127_1187420_1	525909.Afer_1835	2.41e-232	723.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CMS9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS1_k127_1187420_4	28444.JODQ01000006_gene106	2.252e-49	185.0	2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4EJ8Z@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1187420_7	1434325.AZQN01000004_gene1625	5.183e-17	87.0	2E08S@1|root,32VWE@2|Bacteria,4P394@976|Bacteroidetes,47UXB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1201389_1	1121877.JQKF01000020_gene2487	7.869e-175	561.0	COG0477@1|root,COG0477@2|Bacteria,2I5UB@201174|Actinobacteria,4CNH7@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_1201389_0	1229780.BN381_70063	6.537e-216	681.0	COG4108@1|root,COG4108@2|Bacteria,2GKQA@201174|Actinobacteria,3UX1H@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Class II release factor RF3, C-terminal domain	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
MMS1_k127_1227357_2	1173027.Mic7113_5936	2.211e-111	370.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
MMS1_k127_1227357_3	1179773.BN6_15500	1.197e-29	120.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4E5KZ@85010|Pseudonocardiales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
MMS1_k127_1227357_1	1179773.BN6_15510	7.291e-149	484.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4DX5F@85010|Pseudonocardiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
MMS1_k127_1227357_0	1380390.JIAT01000009_gene939	2.442e-184	583.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4CPEP@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_1237863_6	1229780.BN381_10220	4.313e-85	294.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,3UX9M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
MMS1_k127_1237863_4	1313172.YM304_23510	3.616e-102	344.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4CMT3@84992|Acidimicrobiia	84992|Acidimicrobiia	O	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
MMS1_k127_1237863_3	246194.CHY_0383	5.663e-132	433.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,42FGQ@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS1_k127_1237863_5	1229780.BN381_10208	8.34e-93	320.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,3UWHH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
MMS1_k127_1237863_2	1313172.YM304_23430	4.323e-135	442.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CMVB@84992|Acidimicrobiia	84992|Acidimicrobiia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
MMS1_k127_1237863_9	525909.Afer_0772	1.539e-31	124.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CN91@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
MMS1_k127_1237863_10	1451189.CFAL_03300	1.105e-25	109.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,22NEX@1653|Corynebacteriaceae	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
MMS1_k127_1237863_1	188626.HMPREF0321_2191	2.73e-138	460.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,1ZVK2@145357|Dermacoccaceae	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
MMS1_k127_1237863_0	1121877.JQKF01000001_gene1385	1.388e-235	747.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CMYJ@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMS1_k127_1237863_11	525909.Afer_0768	8.32e-20	97.0	2EQHK@1|root,33I3K@2|Bacteria,2HGHC@201174|Actinobacteria,4CNEQ@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
MMS1_k127_1237863_8	1121877.JQKF01000001_gene1383	7.436e-59	214.0	COG1792@1|root,COG1792@2|Bacteria,2HGG4@201174|Actinobacteria,4CNDF@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
MMS1_k127_1237863_7	1121877.JQKF01000001_gene1382	6.45e-65	224.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS1_k127_1258774_1	471852.Tcur_1288	2.531e-77	271.0	COG1492@1|root,COG1492@2|Bacteria,2GJ1W@201174|Actinobacteria,4EHX5@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
MMS1_k127_1258774_0	266117.Rxyl_0635	1.246e-246	790.0	COG1429@1|root,COG1429@2|Bacteria,2GK0U@201174|Actinobacteria,4CPSC@84995|Rubrobacteria	84995|Rubrobacteria	H	CobN/Magnesium Chelatase	-	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel
MMS1_k127_1275350_3	525909.Afer_0477	1.036e-66	237.0	COG0500@1|root,COG2226@2|Bacteria,2HGMM@201174|Actinobacteria,4CNKY@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS1_k127_1275350_2	452652.KSE_04140	1.146e-106	361.0	COG2239@1|root,COG2239@2|Bacteria,2IAC3@201174|Actinobacteria,2M2K2@2063|Kitasatospora	201174|Actinobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
MMS1_k127_1275350_0	675635.Psed_0041	4.06e-160	514.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4E050@85010|Pseudonocardiales	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
MMS1_k127_1275350_1	1121877.JQKF01000013_gene269	2.505e-128	424.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria,4CMVF@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
MMS1_k127_1275350_4	1463855.JOHV01000033_gene1332	2.751e-64	228.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS1_k127_1275350_5	1313172.YM304_09250	9.319e-12	66.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria,4CN1W@84992|Acidimicrobiia	84992|Acidimicrobiia	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1277462_2	1220582.RRU01S_06_00520___1	9.58e-06	53.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2U51V@28211|Alphaproteobacteria,4BCAM@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS1_k127_1277462_1	67267.JNXT01000029_gene2815	1.424e-49	196.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS1_k127_1277462_0	1828.JOKB01000001_gene46	4.709e-69	239.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,4FVAH@85025|Nocardiaceae	201174|Actinobacteria	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
MMS1_k127_1284421_3	765912.Thimo_2029	1.124e-07	53.0	COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,1S5XP@1236|Gammaproteobacteria,1X0ZD@135613|Chromatiales	135613|Chromatiales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
MMS1_k127_1284421_1	1121406.JAEX01000016_gene1873	3.52e-40	162.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_3_5,Polysacc_deac_1
MMS1_k127_1284421_0	1120970.AUBZ01000003_gene173	3.234e-101	336.0	COG3914@1|root,COG3914@2|Bacteria	2|Bacteria	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,Sulfotransfer_3
MMS1_k127_1284421_2	329726.AM1_1906	7.111e-11	70.0	COG0438@1|root,COG0438@2|Bacteria,1G2DD@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_1294729_2	1179773.BN6_30190	2.972e-119	390.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4DYZJ@85010|Pseudonocardiales	201174|Actinobacteria	I	Dehydrogenase	fadB2	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS1_k127_1294729_4	292414.TM1040_1076	6.982e-27	112.0	COG5470@1|root,COG5470@2|Bacteria,1N08K@1224|Proteobacteria,2UCKA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
MMS1_k127_1294729_0	1121877.JQKF01000042_gene1925	3.681e-279	880.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CNJI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS1_k127_1294729_1	469371.Tbis_2805	4.183e-138	453.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4E00Y@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMS1_k127_1294729_3	525904.Tter_0376	1.406e-38	151.0	COG1434@1|root,COG1434@2|Bacteria	2|Bacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
MMS1_k127_130069_2	1120973.AQXL01000127_gene2681	6.4e-47	175.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,278DT@186823|Alicyclobacillaceae	91061|Bacilli	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
MMS1_k127_130069_0	1121877.JQKF01000002_gene1746	1.223e-124	417.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CN74@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
MMS1_k127_130069_1	1382304.JNIL01000001_gene1438	1.973e-96	335.0	COG4262@1|root,COG4262@2|Bacteria,1UYRF@1239|Firmicutes,4I6Q1@91061|Bacilli,279DP@186823|Alicyclobacillaceae	91061|Bacilli	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_133183_4	525909.Afer_1248	2e-07	52.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CMYF@84992|Acidimicrobiia	84992|Acidimicrobiia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
MMS1_k127_133183_2	525909.Afer_1247	6.668e-67	245.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CN07@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
MMS1_k127_133183_1	1121877.JQKF01000014_gene28	2.117e-71	258.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CN6S@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
MMS1_k127_133183_0	1121017.AUFG01000006_gene1184	1.718e-225	707.0	COG3033@1|root,COG3033@2|Bacteria,2GKH3@201174|Actinobacteria,4FIY8@85021|Intrasporangiaceae	201174|Actinobacteria	E	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
MMS1_k127_133183_3	1121877.JQKF01000007_gene1026	3.01e-26	108.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CMQN@84992|Acidimicrobiia	201174|Actinobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	iNJ661.Rv0375c	CO_deh_flav_C,FAD_binding_5
MMS1_k127_1372450_0	1313172.YM304_22260	4.36e-240	764.0	COG0560@1|root,COG3320@1|root,COG0560@2|Bacteria,COG3320@2|Bacteria,2GJVX@201174|Actinobacteria,4CMQQ@84992|Acidimicrobiia	84992|Acidimicrobiia	EQ	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4
MMS1_k127_1372450_1	512565.AMIS_54740	3.456e-38	166.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,2H31X@201174|Actinobacteria,4DJAU@85008|Micromonosporales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
MMS1_k127_1388751_1	944435.AXAJ01000011_gene3043	5.666e-41	166.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,2VM05@28216|Betaproteobacteria,1K2YR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	glycosyl transferase	wcaI	-	-	ko:K03208	-	-	-	-	ko00000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
MMS1_k127_1388751_0	319795.Dgeo_2646	2.609e-103	340.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.10,5.1.3.2	ko:K01784,ko:K12454	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984,R04266	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS1_k127_1391898_0	83332.Rv3432c	3.71e-163	526.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,236S2@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the group II decarboxylase family	gadB	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3432c	Pyridoxal_deC
MMS1_k127_1397982_0	926560.KE387023_gene2049	1.778e-110	384.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
MMS1_k127_1400611_0	1449068.JMLQ01000004_gene1310	3.745e-127	422.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria,4G9F9@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS1_k127_1400611_2	644283.Micau_2282	2.362e-21	101.0	COG3226@1|root,COG3226@2|Bacteria,2IN3D@201174|Actinobacteria,4DDQ0@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
MMS1_k127_1400611_3	926566.Terro_0451	0.0001391	53.0	COG2318@1|root,COG2318@2|Bacteria,3Y501@57723|Acidobacteria,2JJGU@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS1_k127_1400611_1	1160718.SU9_33223	7.193e-55	194.0	COG3324@1|root,COG3324@2|Bacteria,2IKX6@201174|Actinobacteria	201174|Actinobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS1_k127_1404974_5	1463853.JOHW01000037_gene6440	2.766e-82	283.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
MMS1_k127_1404974_3	525909.Afer_1880	3.163e-137	443.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4CMPJ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMS1_k127_1404974_0	1121877.JQKF01000035_gene1958	2.717e-210	660.0	COG0538@1|root,COG0538@2|Bacteria,2IBM8@201174|Actinobacteria,4CNHG@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS1_k127_1404974_6	326424.FRAAL2163	5.578e-64	230.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4ERKZ@85013|Frankiales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
MMS1_k127_1404974_4	1048339.KB913029_gene2830	7.939e-91	308.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4ERQ0@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMS1_k127_1404974_1	649638.Trad_0076	1.227e-155	508.0	COG0138@1|root,COG0138@2|Bacteria,1WIVC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
MMS1_k127_1404974_8	1229780.BN381_130059	3.036e-56	204.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,3UWRP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
MMS1_k127_1404974_2	1121877.JQKF01000016_gene138	1.881e-148	474.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CMSK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
MMS1_k127_1404974_7	1121877.JQKF01000016_gene137	7.567e-63	220.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CMVM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
MMS1_k127_1426467_1	457425.XNR_4476	3.144e-62	226.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS1_k127_1426467_2	455632.SGR_3584	3.274e-40	158.0	COG1040@1|root,COG1040@2|Bacteria,2IRD2@201174|Actinobacteria	201174|Actinobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
MMS1_k127_1426467_0	1449355.JQNR01000002_gene6201	2.567e-102	342.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria	201174|Actinobacteria	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
MMS1_k127_1427999_0	1121877.JQKF01000029_gene2111	1.168e-206	659.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CNF1@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_1428515_6	471852.Tcur_3121	1.349e-05	57.0	COG0265@1|root,COG0265@2|Bacteria,2GJ15@201174|Actinobacteria,4EICZ@85012|Streptosporangiales	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	sprJ	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
MMS1_k127_1428515_2	1313172.YM304_07800	2.086e-50	194.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4CNC4@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
MMS1_k127_1428515_4	1313172.YM304_07670	1.606e-26	113.0	2FBA6@1|root,343GA@2|Bacteria,2H78Y@201174|Actinobacteria,4CN8Z@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1428515_3	1313172.YM304_07660	1.513e-26	111.0	2CC1Y@1|root,32TCV@2|Bacteria,2HGD4@201174|Actinobacteria,4CNAQ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
MMS1_k127_1428515_1	525909.Afer_0329	8.324e-68	241.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CNR1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD_N
MMS1_k127_1428515_5	1203605.HMPREF1531_01727	6.736e-25	106.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4DRN7@85009|Propionibacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
MMS1_k127_1428515_0	1313172.YM304_07620	2.483e-117	390.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4CMU5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_144648_4	103733.JNYO01000039_gene4437	4.759e-52	190.0	COG5646@1|root,COG5646@2|Bacteria,2IINN@201174|Actinobacteria,4E4XD@85010|Pseudonocardiales	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
MMS1_k127_144648_2	196162.Noca_2053	1.843e-74	256.0	COG2514@1|root,COG2514@2|Bacteria,2I4TW@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS1_k127_144648_0	525909.Afer_0284	8.006e-111	387.0	COG1289@1|root,COG1289@2|Bacteria,2GN5P@201174|Actinobacteria,4CNS3@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
MMS1_k127_144648_5	216594.MMAR_3395	8.555e-43	169.0	COG0500@1|root,COG2226@2|Bacteria,2IJ1Q@201174|Actinobacteria,239N6@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS1_k127_144648_3	1003195.SCAT_2733	1.643e-70	246.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
MMS1_k127_144648_6	1122138.AQUZ01000026_gene2970	8.384e-28	115.0	COG0640@1|root,COG0640@2|Bacteria,2IKUI@201174|Actinobacteria,4DRSJ@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
MMS1_k127_144648_1	697303.Thewi_2495	1.612e-93	315.0	COG0249@1|root,COG0249@2|Bacteria,1UVM0@1239|Firmicutes,24ETT@186801|Clostridia	186801|Clostridia	L	PFAM DNA mismatch repair protein MutS	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
MMS1_k127_145164_3	1229780.BN381_10021	2.043e-26	114.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,3UWRW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
MMS1_k127_145164_4	762211.BSTEL_2015	3.223e-12	74.0	COG1432@1|root,COG1432@2|Bacteria,2GUD1@201174|Actinobacteria	201174|Actinobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	NYN
MMS1_k127_145164_1	1120948.KB903244_gene2943	1.445e-109	372.0	COG0531@1|root,COG0531@2|Bacteria,2GIWQ@201174|Actinobacteria,4EB58@85010|Pseudonocardiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS1_k127_145164_0	1370120.AUWR01000008_gene527	1.394e-139	458.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,23CIC@1762|Mycobacteriaceae	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.11,4.1.1.25,4.1.2.27	ko:K01634,ko:K18933	ko00350,ko00410,ko00600,ko00680,ko00770,ko01100,ko01110,ko04071,map00350,map00410,map00600,map00680,map00770,map01100,map01110,map04071	M00100	R00489,R00736,R02464,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
MMS1_k127_145164_2	58123.JOFJ01000021_gene3964	1.667e-101	342.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4EPGJ@85012|Streptosporangiales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17,2.7.1.215,2.7.1.53	ko:K00854,ko:K00862,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00014	R01639,R01901,R07127,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
MMS1_k127_1462061_10	525909.Afer_0052	4.178e-72	251.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4CMXC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
MMS1_k127_1462061_6	1370121.AUWS01000020_gene6705	2.25e-102	349.0	COG2267@1|root,COG2267@2|Bacteria,2I6RV@201174|Actinobacteria,23FF1@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS1_k127_1462061_4	1206731.BAGB01000047_gene5255	1.426e-124	406.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4FYMF@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS1_k127_1462061_13	234621.RER_58640	2.869e-54	201.0	COG0596@1|root,COG0596@2|Bacteria,2I9EM@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS1_k127_1462061_9	710696.Intca_1828	2.355e-74	255.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	nicF	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0044237,GO:0044248	3.5.1.107	ko:K13995	ko00760,ko01120,map00760,map01120	M00622	R03540	RC00950	ko00000,ko00001,ko00002,ko01000	-	-	-	Isochorismatase
MMS1_k127_1462061_0	710696.Intca_1829	0.0	1178.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4FE8A@85021|Intrasporangiaceae	201174|Actinobacteria	EQ	Hydantoinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS1_k127_1462061_1	1464048.JNZS01000003_gene1148	3e-323	1001.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4DGZR@85008|Micromonosporales	201174|Actinobacteria	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS1_k127_1462061_2	1386089.N865_02520	1.289e-203	641.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FFC4@85021|Intrasporangiaceae	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.20	ko:K07749,ko:K18313	-	-	R10640,R10641	RC00014	ko00000,ko01000	-	-	-	CoA_transf_3
MMS1_k127_1462061_12	1464048.JNZS01000003_gene1146	7.343e-60	214.0	COG1802@1|root,COG1802@2|Bacteria,2GMI2@201174|Actinobacteria,4DM6C@85008|Micromonosporales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS1_k127_1462061_5	2002.JOEQ01000005_gene3713	4.467e-108	360.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4EFX0@85012|Streptosporangiales	201174|Actinobacteria	E	HMGL-like	-	-	4.1.3.4,4.1.3.46	ko:K01640,ko:K18314	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090,R10674	RC00502,RC00503,RC01118,RC01205,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
MMS1_k127_1462061_8	1108045.GORHZ_125_01170	2.956e-83	290.0	COG1172@1|root,COG1172@2|Bacteria,2GMJW@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
MMS1_k127_1462061_14	929712.KI912613_gene632	5.197e-29	134.0	COG1879@1|root,COG1879@2|Bacteria,2H2QJ@201174|Actinobacteria	201174|Actinobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
MMS1_k127_1462061_3	1150398.JIBJ01000012_gene2165	6.695e-128	426.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
MMS1_k127_1462061_7	326427.Cagg_1110	5.897e-100	346.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi,375IW@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS1_k127_1462061_11	243159.AFE_0617	1.174e-67	238.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,2NC3G@225057|Acidithiobacillales	225057|Acidithiobacillales	P	ABC transporter, transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
MMS1_k127_146263_1	525909.Afer_1615	7.5e-68	241.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CN02@84992|Acidimicrobiia	84992|Acidimicrobiia	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
MMS1_k127_146263_3	760568.Desku_3094	4.59e-09	67.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,266U0@186807|Peptococcaceae	186801|Clostridia	C	Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubredoxin
MMS1_k127_146263_2	1032480.MLP_23000	2.568e-37	144.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4DR10@85009|Propionibacteriales	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
MMS1_k127_146263_0	926569.ANT_07690	7.31e-101	339.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
MMS1_k127_1494677_0	1121877.JQKF01000008_gene622	4.85e-108	358.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4CMYN@84992|Acidimicrobiia	84992|Acidimicrobiia	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
MMS1_k127_1494677_1	405948.SACE_3049	4.709e-82	292.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4E1BH@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS1_k127_1494677_2	1123023.JIAI01000001_gene7046	9.775e-70	256.0	COG0531@1|root,COG0531@2|Bacteria,2GNUF@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS1_k127_149932_0	1120972.AUMH01000003_gene3036	5.68e-156	506.0	COG0477@1|root,COG0477@2|Bacteria,1VQVW@1239|Firmicutes,4HW7A@91061|Bacilli	91061|Bacilli	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
MMS1_k127_149932_1	105425.BBPL01000026_gene436	1.099e-71	253.0	COG1295@1|root,COG1295@2|Bacteria,2HMQ0@201174|Actinobacteria,2NGCJ@228398|Streptacidiphilus	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
MMS1_k127_149932_4	479431.Namu_2002	1.238e-35	145.0	COG1277@1|root,COG1277@2|Bacteria,2GSIR@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
MMS1_k127_149932_2	479431.Namu_2001	1.816e-66	239.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria,4ESB1@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,PLDc_N
MMS1_k127_149932_5	68170.KL590477_gene2634	2.581e-17	84.0	2ASXR@1|root,31IDA@2|Bacteria,2GWS7@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
MMS1_k127_149932_3	1206733.BAGC01000114_gene7148	5.1e-60	213.0	COG0640@1|root,COG0640@2|Bacteria,2IIA5@201174|Actinobacteria,4G1J7@85025|Nocardiaceae	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS1_k127_149932_6	263358.VAB18032_13595	9.59e-13	77.0	COG0392@1|root,COG0671@1|root,COG3642@1|root,COG0392@2|Bacteria,COG0671@2|Bacteria,COG3642@2|Bacteria,2GMAV@201174|Actinobacteria,4DFJ3@85008|Micromonosporales	201174|Actinobacteria	IT	Lysylphosphatidylglycerol synthase TM region	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2
MMS1_k127_1501443_2	1283299.AUKG01000001_gene1300	3.287e-107	358.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CQZN@84995|Rubrobacteria	84995|Rubrobacteria	V	Domain of unknown function (DUF4162)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,DUF4162
MMS1_k127_1501443_0	1211815.CBYP010000066_gene1586	5.208e-169	538.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4ESG3@85013|Frankiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
MMS1_k127_1501443_4	1313172.YM304_27520	2.585e-54	202.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CN5T@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS1_k127_1501443_3	1121877.JQKF01000004_gene1136	1.041e-93	314.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4CMYZ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS1_k127_1501443_1	1229780.BN381_330051	6.658e-108	354.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,3UWBA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
MMS1_k127_1509660_3	1169161.KB897728_gene660	2.28e-09	70.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
MMS1_k127_1509660_1	1121877.JQKF01000085_gene485	1.016e-56	207.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4CN5Z@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
MMS1_k127_1509660_0	1194972.MVAC_24176	6.312e-146	471.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,234A3@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS1_k127_1509660_2	479432.Sros_7917	4.047e-32	128.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,4EM54@85012|Streptosporangiales	201174|Actinobacteria	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
MMS1_k127_1515267_5	1382359.JIAL01000001_gene212	9.421e-50	181.0	COG1397@1|root,COG1397@2|Bacteria,3Y94D@57723|Acidobacteria	57723|Acidobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
MMS1_k127_1515267_1	1121946.AUAX01000016_gene4739	2.714e-93	315.0	COG1357@1|root,COG1357@2|Bacteria,2GN74@201174|Actinobacteria,4DB8R@85008|Micromonosporales	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,Pentapeptide
MMS1_k127_1515267_0	436229.JOEH01000015_gene5924	2.004e-182	596.0	COG0577@1|root,COG0577@2|Bacteria,2GKF3@201174|Actinobacteria,2NHDH@228398|Streptacidiphilus	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
MMS1_k127_1515267_2	105422.BBPM01000001_gene4814	1.063e-92	312.0	COG1136@1|root,COG1136@2|Bacteria,2GM25@201174|Actinobacteria,2NI20@228398|Streptacidiphilus	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS1_k127_1515267_3	1449347.JQLN01000003_gene5819	1.352e-78	267.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,2M1TZ@2063|Kitasatospora	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS1_k127_1515267_6	234621.RER_36000	6.803e-37	145.0	2B1QU@1|root,31U6H@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
MMS1_k127_1515267_4	1449353.JQMQ01000004_gene6152	9.646e-67	247.0	COG0596@1|root,COG0596@2|Bacteria,2I3WE@201174|Actinobacteria,2NJJC@228398|Streptacidiphilus	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS1_k127_1515267_7	1206731.BAGB01000026_gene3061	2.269e-20	95.0	COG3324@1|root,COG3324@2|Bacteria,2GP30@201174|Actinobacteria,4G93E@85025|Nocardiaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMS1_k127_1524650_4	43759.JNWK01000031_gene6093	3.325e-12	68.0	COG1215@1|root,COG1215@2|Bacteria,2GP1D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS1_k127_1524650_0	266117.Rxyl_0357	5.855e-107	363.0	COG2079@1|root,COG2079@2|Bacteria,2I8CW@201174|Actinobacteria,4CT8P@84995|Rubrobacteria	84995|Rubrobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMS1_k127_1524650_3	266117.Rxyl_0356	7.281e-41	160.0	COG4126@1|root,COG4126@2|Bacteria,2INMJ@201174|Actinobacteria	201174|Actinobacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1525137_3	1122609.AUGT01000009_gene3448	7.452e-30	130.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4DPSE@85009|Propionibacteriales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
MMS1_k127_1525137_2	1121877.JQKF01000009_gene522	2.847e-41	155.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4CN4I@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
MMS1_k127_1525137_0	525909.Afer_0426	3.881e-125	408.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CMSV@84992|Acidimicrobiia	84992|Acidimicrobiia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
MMS1_k127_1525137_1	525909.Afer_0425	2.603e-76	261.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CN4S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
MMS1_k127_1525137_4	1401328.P856_124	4.408e-07	51.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2U717@28211|Alphaproteobacteria,2JS4T@204441|Rhodospirillales	204441|Rhodospirillales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
MMS1_k127_1532839_13	1121877.JQKF01000002_gene1672	1.255e-33	132.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CMXX@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
MMS1_k127_1532839_15	1050202.KB913024_gene1012	2.552e-10	69.0	COG1862@1|root,COG1862@2|Bacteria,2I29T@201174|Actinobacteria,4099Y@622450|Actinopolysporales	201174|Actinobacteria	U	Preprotein translocase subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
MMS1_k127_1532839_3	1229780.BN381_50115	7.719e-123	404.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,3UWHB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
MMS1_k127_1532839_4	405948.SACE_3516	2.778e-122	399.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4DXHC@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	gctA	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
MMS1_k127_1532839_6	591158.SSMG_01474	1.197e-110	370.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria	201174|Actinobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	catJ	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
MMS1_k127_1532839_5	33876.JNXY01000020_gene4364	1.058e-115	383.0	COG0599@1|root,COG2267@1|root,COG0599@2|Bacteria,COG2267@2|Bacteria,2GITB@201174|Actinobacteria	201174|Actinobacteria	I	decarboxylase	pcaC	-	3.1.1.24,4.1.1.44	ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
MMS1_k127_1532839_10	525909.Afer_1645	4.509e-58	207.0	COG1738@1|root,COG1738@2|Bacteria,2IGCP@201174|Actinobacteria	201174|Actinobacteria	S	Putative vitamin uptake transporter	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
MMS1_k127_1532839_12	1121877.JQKF01000027_gene2479	9.092e-52	188.0	COG0780@1|root,COG0780@2|Bacteria,2GS82@201174|Actinobacteria,4CNEJ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
MMS1_k127_1532839_8	1121877.JQKF01000056_gene855	7.619e-89	298.0	COG0603@1|root,COG0603@2|Bacteria,2I8NZ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
MMS1_k127_1532839_0	1382304.JNIL01000001_gene3288	6.892e-247	789.0	COG2366@1|root,COG2366@2|Bacteria,1VQX0@1239|Firmicutes,4HTG2@91061|Bacilli,279FZ@186823|Alicyclobacillaceae	91061|Bacilli	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
MMS1_k127_1532839_7	1229780.BN381_50114	2.714e-90	308.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria	201174|Actinobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
MMS1_k127_1532839_1	1236902.ANAS01000008_gene2372	4.774e-201	641.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4EFFB@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS1_k127_1532839_2	1463900.JOIX01000057_gene3085	1.247e-168	540.0	COG0160@1|root,COG0160@2|Bacteria,2GKVH@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS1_k127_1532839_9	211114.JOEF01000004_gene6523	9.024e-87	303.0	COG1167@1|root,COG1167@2|Bacteria,2GM6I@201174|Actinobacteria,4DYS8@85010|Pseudonocardiales	201174|Actinobacteria	EK	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
MMS1_k127_1532839_14	1487923.DP73_02230	2.808e-22	104.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia,261ZT@186807|Peptococcaceae	186801|Clostridia	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMS1_k127_1532839_11	1394178.AWOO02000038_gene9062	9.574e-57	202.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4EKUA@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS1_k127_1536340_2	1385519.N801_08575	6.319e-50	184.0	28RC2@1|root,2ZDRH@2|Bacteria,2GNI9@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
MMS1_k127_1536340_0	867903.ThesuDRAFT_02331	2.296e-109	369.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3WCZC@538999|Clostridiales incertae sedis	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS1_k127_1536340_3	1121877.JQKF01000009_gene519	1.607e-40	158.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CN72@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
MMS1_k127_1536340_1	471852.Tcur_4284	1.464e-60	212.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4EIMC@85012|Streptosporangiales	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
MMS1_k127_1543440_13	1121877.JQKF01000002_gene1617	2.42e-38	143.0	COG1141@1|root,COG1141@2|Bacteria,2IKKX@201174|Actinobacteria,4CN8X@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
MMS1_k127_1543440_0	525909.Afer_0907	5.149e-267	832.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CMRU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Proteasomal ATPase OB/ID domain	arc	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
MMS1_k127_1543440_3	1121877.JQKF01000002_gene1619	1.951e-197	627.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CMSZ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pup-ligase protein	dop	-	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
MMS1_k127_1543440_15	1121877.JQKF01000002_gene1620	8.685e-18	85.0	2E9C2@1|root,333JS@2|Bacteria,2HGHP@201174|Actinobacteria,4CNEV@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
MMS1_k127_1543440_6	1121877.JQKF01000002_gene1621	5.308e-92	310.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4CMX8@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
MMS1_k127_1543440_5	1121877.JQKF01000002_gene1622	2.347e-101	335.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4CMY5@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
MMS1_k127_1543440_1	1313172.YM304_26020	6.489e-231	721.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CMS0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
MMS1_k127_1543440_10	1121877.JQKF01000002_gene1624	2.604e-54	196.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CNAZ@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
MMS1_k127_1543440_14	525909.Afer_0914	7.61e-26	111.0	2ANEI@1|root,31DD5@2|Bacteria,2HGZX@201174|Actinobacteria,4CP05@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1543440_12	44060.JODL01000025_gene147	5.991e-48	179.0	COG0406@1|root,COG0406@2|Bacteria,2INQD@201174|Actinobacteria	201174|Actinobacteria	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
MMS1_k127_1543440_19	1313172.YM304_25990	0.000334	50.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS1_k127_1543440_8	525909.Afer_0917	3.333e-79	272.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CN3F@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
MMS1_k127_1543440_2	1229780.BN381_400030	9.277e-211	685.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,3UWB3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
MMS1_k127_1543440_4	1229780.BN381_400026	8.943e-124	416.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
MMS1_k127_1543440_17	1121877.JQKF01000002_gene1631	4.046e-14	79.0	2DDS5@1|root,2ZJ1Y@2|Bacteria,2HDMP@201174|Actinobacteria,4CP3T@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1543440_18	525909.Afer_0921	3.206e-11	72.0	2AN5U@1|root,31D3R@2|Bacteria,2HGRH@201174|Actinobacteria,4CNU6@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1543440_7	1280950.HJO_03060	1.241e-79	278.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRIH@28211|Alphaproteobacteria,43WPX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
MMS1_k127_1543440_9	1121877.JQKF01000002_gene1635	2.609e-77	276.0	2F1PM@1|root,33UPX@2|Bacteria,2H4R3@201174|Actinobacteria,4CN41@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1543440_16	935840.JAEQ01000017_gene1870	1.028e-15	83.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2U7H0@28211|Alphaproteobacteria,43K5Q@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Aminoacyl-tRNA editing domain	ybaK	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
MMS1_k127_1543440_11	1121877.JQKF01000002_gene1636	8.704e-52	194.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CNRZ@84992|Acidimicrobiia	84992|Acidimicrobiia	L	AP endonuclease family 2	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
MMS1_k127_1544080_4	312284.A20C1_13366	1.51e-26	111.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,3UXJK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Peptidase C26	-	-	-	-	-	-	-	-	-	-	-	-	GATase
MMS1_k127_1544080_1	68260.JOAY01000027_gene4171	3.082e-94	330.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_1544080_0	290340.AAur_pTC20183	2.037e-165	529.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,1W8BI@1268|Micrococcaceae	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS1_k127_1544080_2	1121877.JQKF01000002_gene1731	5.661e-69	242.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4CNHE@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
MMS1_k127_1544080_3	1223545.GS4_20_01920	8.284e-30	128.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,4GBVB@85026|Gordoniaceae	201174|Actinobacteria	S	Beta-lactamase superfamily domain	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMS1_k127_1544080_5	1229780.BN381_40081	1.658e-13	79.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,3UWTG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS1_k127_1544203_2	1313172.YM304_20490	2.698e-42	162.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CN5V@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Guanylate kinase homologues.	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
MMS1_k127_1544203_3	525909.Afer_1694	1.045e-21	99.0	COG1758@1|root,COG1758@2|Bacteria,2HG9P@201174|Actinobacteria,4CN82@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
MMS1_k127_1544203_1	1229780.BN381_50149	3.555e-116	387.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,3UWCS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
MMS1_k127_1544203_0	1157637.KB892156_gene3971	2.046e-131	425.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
MMS1_k127_154436_4	479432.Sros_2956	1.932e-79	276.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4EMYR@85012|Streptosporangiales	201174|Actinobacteria	E	Receptor family ligand binding region	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS1_k127_154436_1	469371.Tbis_1470	1.105e-105	352.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4DYKY@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMS1_k127_154436_0	561175.KB894098_gene5334	1.206e-137	449.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4EHK7@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMS1_k127_154436_2	1246995.AFR_10405	7.554e-97	323.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DA7P@85008|Micromonosporales	201174|Actinobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMS1_k127_154436_3	1283287.KB822576_gene3729	4.851e-85	287.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DQD4@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid amide ABC transporter ATP-binding protein 2, HAAT family	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMS1_k127_154436_7	68170.KL590535_gene3738	7.322e-14	76.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,4E5PE@85010|Pseudonocardiales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
MMS1_k127_154436_6	1869.MB27_21030	6.484e-24	107.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS1_k127_154436_5	1206729.BAFZ01000036_gene4774	7.952e-58	216.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4FX0X@85025|Nocardiaceae	201174|Actinobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
MMS1_k127_1550273_8	1229780.BN381_150069	7.902e-19	87.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,3UX6U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	B12 binding domain	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
MMS1_k127_1550273_4	1229780.BN381_100132	1.37e-105	349.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,3UX97@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS1_k127_1550273_7	1229780.BN381_100131	1.351e-47	179.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
MMS1_k127_1550273_5	1313172.YM304_36860	6.508e-70	241.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4CN2J@84992|Acidimicrobiia	84992|Acidimicrobiia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
MMS1_k127_1550273_6	1184607.AUCHE_16_01430	1.379e-63	232.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4F6UE@85018|Dermatophilaceae	201174|Actinobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
MMS1_k127_1550273_0	525909.Afer_0111	5.373e-188	595.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CMX1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ACT domain	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
MMS1_k127_1550273_3	66875.JODY01000015_gene720	4.03e-119	391.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
MMS1_k127_1550273_1	500153.JOEK01000001_gene3995	8.413e-147	474.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	dapC	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS1_k127_1550273_2	1121877.JQKF01000020_gene2504	1.268e-145	468.0	COG0641@1|root,COG0641@2|Bacteria,2GMTV@201174|Actinobacteria	201174|Actinobacteria	V	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Radical_SAM,SEC-C,SPASM
MMS1_k127_1555348_4	1121877.JQKF01000001_gene1322	8.232e-65	228.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CNFZ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS1_k127_1555348_12	525909.Afer_0565	9.118e-22	95.0	COG1141@1|root,COG1141@2|Bacteria,2HH2S@201174|Actinobacteria,4CP2W@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Divergent 4Fe-4S mono-cluster	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
MMS1_k127_1555348_6	1380390.JIAT01000010_gene4179	6.416e-62	231.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4CPPA@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS1_k127_1555348_3	579138.Zymop_0784	7.241e-69	242.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,2K0E3@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMS1_k127_1555348_8	525909.Afer_0562	8.758e-30	121.0	COG2146@1|root,COG2146@2|Bacteria,2HGVU@201174|Actinobacteria,4CNWW@84992|Acidimicrobiia	84992|Acidimicrobiia	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
MMS1_k127_1555348_7	479434.Sthe_1524	2.423e-50	196.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
MMS1_k127_1555348_5	1125971.ASJB01000028_gene7741	3.56e-64	229.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4E086@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase carnithine racemase	echA21	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS1_k127_1555348_9	1229780.BN381_210073	5.323e-28	116.0	2FF8Q@1|root,3476J@2|Bacteria,2H7PN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1555348_0	525909.Afer_0559	4.923e-94	328.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CN3Q@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
MMS1_k127_1555348_2	1121877.JQKF01000001_gene1309	2.344e-84	287.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CMX9@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS1_k127_1555348_1	1121877.JQKF01000001_gene1308	4.32e-92	323.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4CN2H@84992|Acidimicrobiia	84992|Acidimicrobiia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMS1_k127_1555348_10	298655.KI912266_gene5647	3.36e-24	113.0	COG3550@1|root,COG3550@2|Bacteria,2I2QD@201174|Actinobacteria	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
MMS1_k127_1555348_11	525909.Afer_0543	3.44e-22	96.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CMQU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
MMS1_k127_1565374_3	1187851.A33M_3618	2.828e-67	238.0	COG0391@1|root,COG0391@2|Bacteria,1NK78@1224|Proteobacteria,2TUUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LPPG Fo 2-phospho-L-lactate transferase	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
MMS1_k127_1565374_2	1229780.BN381_10186	4.662e-72	250.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,3UXCJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	F420-0:Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
MMS1_k127_1565374_0	1121877.JQKF01000001_gene1358	1.195e-85	301.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS1_k127_1565374_1	1121877.JQKF01000001_gene1357	3.614e-84	291.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CMYG@84992|Acidimicrobiia	84992|Acidimicrobiia	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS1_k127_1565374_4	1121877.JQKF01000001_gene1356	1.184e-41	163.0	2968S@1|root,2ZTIT@2|Bacteria,2HEBZ@201174|Actinobacteria,4CNCH@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1568360_2	235985.BBPN01000001_gene1299	1.63e-42	163.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,2NE8R@228398|Streptacidiphilus	201174|Actinobacteria	L	Ribonuclease HII	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
MMS1_k127_1568360_0	1121877.JQKF01000001_gene1337	3.653e-197	625.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CMT7@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS1_k127_1568360_1	1121877.JQKF01000001_gene1338	1.119e-156	509.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4CMW0@84992|Acidimicrobiia	84992|Acidimicrobiia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS1_k127_1568360_3	525909.Afer_0719	5.229e-39	150.0	COG0320@1|root,COG0321@1|root,COG0320@2|Bacteria,COG0321@2|Bacteria,2GKD4@201174|Actinobacteria,4CMR4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
MMS1_k127_1568692_5	489825.LYNGBM3L_67840	3.929e-24	108.0	COG0615@1|root,COG0615@2|Bacteria,1G8Q0@1117|Cyanobacteria,1HH3Q@1150|Oscillatoriales	1117|Cyanobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
MMS1_k127_1568692_2	663610.JQKO01000001_gene1068	1.611e-45	175.0	COG4976@1|root,COG4976@2|Bacteria,1QZZ0@1224|Proteobacteria,2TYH1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1568692_0	926550.CLDAP_21470	1.397e-105	355.0	COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
MMS1_k127_1568692_4	768670.Calni_1969	1.336e-40	166.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pimB	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_1568692_3	1001585.MDS_3746	5.777e-44	172.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS1_k127_1568692_1	290318.Cvib_0631	1.289e-59	219.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1FEDE@1090|Chlorobi	1090|Chlorobi	H	May be the GTPase, regulating ATP sulfurylase activity	-	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
MMS1_k127_1579996_2	1121877.JQKF01000003_gene1451	6.327e-53	190.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CN6V@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
MMS1_k127_1579996_4	690850.Desaf_2867	4.478e-33	132.0	COG3324@1|root,COG3324@2|Bacteria,1PV0A@1224|Proteobacteria,4367N@68525|delta/epsilon subdivisions,2X9GI@28221|Deltaproteobacteria,2MD8H@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMS1_k127_1579996_1	590998.Celf_2991	4.569e-144	476.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	lldD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iNJ661.Rv1872c	FMN_dh
MMS1_k127_1579996_0	1312954.KI914849_gene1987	2.674e-168	533.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria	201174|Actinobacteria	C	Acetamidase formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
MMS1_k127_1579996_3	525909.Afer_1536	1.027e-49	181.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CMRK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS1_k127_1580741_0	1121877.JQKF01000003_gene1540	7.934e-166	537.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CNAI@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
MMS1_k127_1580741_1	391625.PPSIR1_06983	3.116e-131	431.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2YUK3@29|Myxococcales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
MMS1_k127_1580741_2	1229780.BN381_90009	8.116e-130	432.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,3UWHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_1580741_3	2074.JNYD01000005_gene3000	0.0003204	50.0	COG1309@1|root,COG1309@2|Bacteria,2IC64@201174|Actinobacteria,4E5TE@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS1_k127_1580870_3	1246995.AFR_04305	6.047e-20	90.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1580870_4	287986.DV20_26085	1.967e-17	91.0	COG4544@1|root,COG4544@2|Bacteria,2IIXE@201174|Actinobacteria,4E9QW@85010|Pseudonocardiales	201174|Actinobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1580870_2	298654.FraEuI1c_2357	3.139e-72	265.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,4ES7K@85013|Frankiales	201174|Actinobacteria	L	impB/mucB/samB family	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
MMS1_k127_1580870_1	65497.JODV01000026_gene1851	6.054e-101	337.0	COG2513@1|root,COG2513@2|Bacteria,2GJZZ@201174|Actinobacteria,4E0PY@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
MMS1_k127_1580870_0	521098.Aaci_0799	8.683e-142	466.0	COG2079@1|root,COG2079@2|Bacteria,1TRR8@1239|Firmicutes,4HAUS@91061|Bacilli	91061|Bacilli	S	2-methylcitrate dehydratase	prpD	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
MMS1_k127_1580870_5	1449976.KALB_8083	2.343e-06	51.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DYKC@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
MMS1_k127_1603247_1	635013.TherJR_2593	3.325e-71	250.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,26144@186807|Peptococcaceae	186801|Clostridia	S	PFAM PHP domain	-	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
MMS1_k127_1603247_2	329726.AM1_3889	9.819e-32	126.0	COG2329@1|root,COG2329@2|Bacteria,1G7DQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
MMS1_k127_1603247_0	1229780.BN381_130019	1.166e-251	797.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,3UWF7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS1_k127_1603345_5	1121877.JQKF01000018_gene2571	3.779e-42	156.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CMZF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	sigR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS1_k127_1603345_6	525909.Afer_1917	2.035e-19	90.0	29XP9@1|root,30JEV@2|Bacteria,2HGER@201174|Actinobacteria,4CNCS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMS1_k127_1603345_2	1229780.BN381_110020	2.564e-69	248.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,3UXC9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
MMS1_k127_1603345_3	1313172.YM304_37680	3.501e-65	234.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CN76@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
MMS1_k127_1603345_1	525909.Afer_1913	1.533e-69	240.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CNRA@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
MMS1_k127_1603345_4	1176165.CAJD01000011_gene525	7.223e-45	169.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4F9DC@85019|Brevibacteriaceae	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
MMS1_k127_1603345_0	525909.Afer_1911	6.314e-83	283.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CNEH@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
MMS1_k127_1603345_7	1229780.BN381_110027	4.463e-14	76.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,3UWX7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
MMS1_k127_1607819_4	350058.Mvan_3264	3.82e-43	163.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,2377M@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	rve
MMS1_k127_1607819_0	1288826.MSNKSG1_03515	2.37e-136	447.0	COG4974@1|root,COG4974@2|Bacteria,1R72R@1224|Proteobacteria,1S8CW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS1_k127_1607819_3	1097668.BYI23_A001790	1.234e-81	282.0	COG4974@1|root,COG4974@2|Bacteria,1R63X@1224|Proteobacteria,2VT3A@28216|Betaproteobacteria,1K0IA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
MMS1_k127_1607819_1	237609.PSAKL28_30590	1.032e-99	340.0	COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,1S4Y0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS1_k127_1607819_2	350058.Mvan_3264	2.663e-83	282.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,2377M@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	rve
MMS1_k127_1613046_4	1121367.AQXC01000009_gene264	1.6e-67	248.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,22KQX@1653|Corynebacteriaceae	201174|Actinobacteria	L	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
MMS1_k127_1613046_3	525909.Afer_1925	3.016e-85	290.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4CN1K@84992|Acidimicrobiia	84992|Acidimicrobiia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
MMS1_k127_1613046_5	1380390.JIAT01000011_gene2844	2.708e-51	192.0	COG2050@1|root,COG2050@2|Bacteria,2HPRC@201174|Actinobacteria,4CR4I@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
MMS1_k127_1613046_2	1229780.BN381_100019	6.735e-155	494.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdD	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS1_k127_1613046_1	1121438.JNJA01000022_gene411	1.958e-161	527.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,2M96K@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
MMS1_k127_1613046_0	525909.Afer_0243	2.695e-238	743.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CMV7@84992|Acidimicrobiia	2|Bacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
MMS1_k127_1618174_2	1121877.JQKF01000012_gene342	6.544e-61	213.0	COG0683@1|root,COG0683@2|Bacteria,2HFKF@201174|Actinobacteria,4CP0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS1_k127_1618174_0	2074.JNYD01000016_gene4185	9.988e-150	489.0	COG2368@1|root,COG2368@2|Bacteria,2GKIQ@201174|Actinobacteria,4DYKH@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase	-	-	1.14.13.166,1.14.13.29,1.14.14.9	ko:K00483,ko:K21726	ko00350,ko00627,ko01120,ko01220,map00350,map00627,map01120,map01220	-	R02698,R03023,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
MMS1_k127_1618174_1	2074.JNYD01000016_gene4189	3.526e-84	294.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_161851_3	1385520.N802_08380	1.531e-73	253.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4FE5C@85021|Intrasporangiaceae	201174|Actinobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
MMS1_k127_161851_5	710696.Intca_2806	3.568e-66	229.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,4FFNF@85021|Intrasporangiaceae	201174|Actinobacteria	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS1_k127_161851_4	1160137.KB907307_gene2716	1.108e-67	239.0	COG1414@1|root,COG1414@2|Bacteria,2I3TP@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMS1_k127_161851_2	285535.JOEY01000003_gene10501	1.186e-95	320.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
MMS1_k127_161851_1	1394178.AWOO02000014_gene7675	3.79e-101	337.0	COG1028@1|root,COG1028@2|Bacteria,2IAGY@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS1_k127_161851_0	285514.JNWO01000001_gene4232	1.337e-151	482.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria	201174|Actinobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
MMS1_k127_1630272_1	1121877.JQKF01000009_gene527	3.315e-98	329.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CN1I@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMS1_k127_1630272_5	525909.Afer_0419	2.018e-70	244.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CMZ1@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMS1_k127_1630272_0	1121877.JQKF01000009_gene529	3.264e-189	599.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CMWZ@84992|Acidimicrobiia	84992|Acidimicrobiia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
MMS1_k127_1630272_9	525909.Afer_0417	3.852e-55	198.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CN1G@84992|Acidimicrobiia	84992|Acidimicrobiia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
MMS1_k127_1630272_16	1313172.YM304_08430	1.211e-21	96.0	COG1841@1|root,COG1841@2|Bacteria,2HGDQ@201174|Actinobacteria,4CNC3@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
MMS1_k127_1630272_7	1121877.JQKF01000009_gene532	1.762e-69	239.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CN34@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
MMS1_k127_1630272_11	525909.Afer_0414	3.097e-39	149.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4CNBZ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
MMS1_k127_1630272_4	1203605.HMPREF1531_00167	6.288e-71	244.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4DNFZ@85009|Propionibacteriales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
MMS1_k127_1630272_10	1313172.YM304_08390	2.133e-54	193.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4CN3X@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
MMS1_k127_1630272_15	1043205.AFYF01000076_gene1604	2.617e-23	104.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4FH9A@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
MMS1_k127_1630272_3	1121877.JQKF01000009_gene536	4.485e-84	282.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CMX7@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
MMS1_k127_1630272_13	443254.Marpi_0869	2.367e-28	117.0	COG0198@1|root,COG0198@2|Bacteria,2GD31@200918|Thermotogae	200918|Thermotogae	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
MMS1_k127_1630272_8	1121877.JQKF01000009_gene538	2.143e-65	226.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CMZN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
MMS1_k127_1630272_14	1121877.JQKF01000009_gene539	3.103e-27	113.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4CN9S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
MMS1_k127_1630272_17	1121440.AUMA01000007_gene1314	2.985e-11	66.0	COG0255@1|root,COG0255@2|Bacteria,1Q1R3@1224|Proteobacteria,42WYX@68525|delta/epsilon subdivisions,2WSTS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
MMS1_k127_1630272_6	525909.Afer_0405	7.22e-70	238.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4CN0S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
MMS1_k127_1630272_2	1121877.JQKF01000009_gene542	1.448e-93	316.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CMU9@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
MMS1_k127_1630272_12	1229780.BN381_450092	7.31e-29	122.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,3UWV3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
MMS1_k127_1639860_2	1463917.JODC01000007_gene7648	6.647e-58	214.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
MMS1_k127_1639860_6	1082931.KKY_2542	3.543e-34	142.0	COG0600@1|root,COG0600@2|Bacteria,1PGJI@1224|Proteobacteria,2V8ZB@28211|Alphaproteobacteria,3N91H@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15554	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	BPD_transp_1
MMS1_k127_1639860_5	1449976.KALB_3536	2.058e-49	186.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4DY5P@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K15554	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	BPD_transp_1
MMS1_k127_1639860_1	1151118.KB895787_gene1326	2.519e-72	257.0	COG1116@1|root,COG1116@2|Bacteria,2GM73@201174|Actinobacteria,1WCHY@1268|Micrococcaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
MMS1_k127_1639860_0	330084.JNYZ01000025_gene2629	6.731e-171	554.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria,4DXG7@85010|Pseudonocardiales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS1_k127_1639860_3	105425.BBPL01000074_gene3840	7.54e-56	202.0	COG2020@1|root,COG2020@2|Bacteria,2HUDA@201174|Actinobacteria,2NIQ9@228398|Streptacidiphilus	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMS1_k127_1639860_4	298655.KI912266_gene6054	2.266e-55	204.0	COG0500@1|root,COG2226@2|Bacteria,2GNVG@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS1_k127_1646941_3	1445613.JALM01000056_gene3981	2.139e-48	175.0	COG0365@1|root,COG0365@2|Bacteria,2GJSQ@201174|Actinobacteria,4DZ57@85010|Pseudonocardiales	201174|Actinobacteria	I	synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_1646941_5	469378.Ccur_09490	8.483e-35	147.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CUWJ@84998|Coriobacteriia	84998|Coriobacteriia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
MMS1_k127_1646941_1	446468.Ndas_0898	7.056e-105	357.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4EG2K@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS1_k127_1646941_2	525909.Afer_1243	2.243e-85	294.0	COG0812@1|root,COG0812@2|Bacteria,2HG0Y@201174|Actinobacteria,4CMXR@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
MMS1_k127_1646941_7	1123065.ATWL01000002_gene1762	4.289e-07	61.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria	201174|Actinobacteria	D	cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
MMS1_k127_1646941_0	1160718.SU9_23210	3.418e-140	454.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMS1_k127_1646941_6	471855.Shel_08900	1.656e-17	91.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CUPU@84998|Coriobacteriia	84998|Coriobacteriia	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
MMS1_k127_1646941_4	525909.Afer_1239	1.676e-38	154.0	COG0325@1|root,COG0325@2|Bacteria,2HGAF@201174|Actinobacteria,4CN9H@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
MMS1_k127_1653744_1	1229780.BN381_600007	7.706e-93	312.0	28PS2@1|root,2ZCDQ@2|Bacteria,2IGPK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1653744_0	1048339.KB913029_gene1708	2.09e-187	601.0	COG0827@1|root,COG0827@2|Bacteria,2I8PF@201174|Actinobacteria,4EUQW@85013|Frankiales	201174|Actinobacteria	L	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
MMS1_k127_1653744_2	1297742.A176_03136	7.361e-41	163.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,42N51@68525|delta/epsilon subdivisions,2WKBV@28221|Deltaproteobacteria,2YUYZ@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS1_k127_1657767_0	1121013.P873_11090	1.742e-178	576.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,1PXMG@1224|Proteobacteria,1SMYY@1236|Gammaproteobacteria,1XABQ@135614|Xanthomonadales	135614|Xanthomonadales	L	Domain of unknown function DUF83	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
MMS1_k127_1657767_1	1173020.Cha6605_3531	1.043e-13	74.0	COG2161@1|root,COG2161@2|Bacteria,1G97A@1117|Cyanobacteria	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
MMS1_k127_1662883_1	1443125.Z962_08455	0.0002695	50.0	2EM6R@1|root,33EVY@2|Bacteria,1VYH2@1239|Firmicutes,24YVF@186801|Clostridia,36QAV@31979|Clostridiaceae	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
MMS1_k127_1662883_0	1443665.JACA01000048_gene5369	1.261e-18	92.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	Z012_08285	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
MMS1_k127_1680077_2	1380763.BG53_10660	5.011e-38	152.0	COG1414@1|root,COG1414@2|Bacteria,1TQH9@1239|Firmicutes,4HCMT@91061|Bacilli,26XEU@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMS1_k127_1680077_1	1121377.KB906421_gene3709	5.992e-71	253.0	COG2301@1|root,COG2301@2|Bacteria,1WM1N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
MMS1_k127_1680077_0	926560.KE387025_gene4093	1.104e-128	417.0	COG1804@1|root,COG1804@2|Bacteria,1WKYE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS1_k127_1680102_0	1380393.JHVP01000002_gene1696	1.709e-65	243.0	COG1680@1|root,COG2385@1|root,COG1680@2|Bacteria,COG2385@2|Bacteria,2HEYF@201174|Actinobacteria,4ESKX@85013|Frankiales	201174|Actinobacteria	D	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIID
MMS1_k127_1680102_4	1121877.JQKF01000053_gene463	4.01e-27	124.0	2AQYZ@1|root,31G7P@2|Bacteria,2HGVJ@201174|Actinobacteria,4CNWG@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1680102_2	1121877.JQKF01000053_gene464	1.016e-50	195.0	COG0438@1|root,COG0438@2|Bacteria,2HGNS@201174|Actinobacteria,4CNQP@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS1_k127_1680102_1	1121877.JQKF01000053_gene465	2.922e-52	204.0	COG0438@1|root,COG0438@2|Bacteria,2HGMK@201174|Actinobacteria,4CNKW@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1680102_3	1047013.AQSP01000140_gene2464	1.04e-28	131.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
MMS1_k127_1683342_3	106370.Francci3_2247	5.505e-87	296.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4ERC3@85013|Frankiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_1683342_2	1230476.C207_00116	5e-91	312.0	COG1804@1|root,COG1804@2|Bacteria,1Q3F3@1224|Proteobacteria,2TRN2@28211|Alphaproteobacteria,3K2V4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS1_k127_1683342_0	675635.Psed_5277	1.815e-245	766.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DZT6@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
MMS1_k127_1683342_1	1123023.JIAI01000010_gene8488	5.923e-207	661.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4DZ8S@85010|Pseudonocardiales	201174|Actinobacteria	I	Biotin carboxylase	accBC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3285	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
MMS1_k127_1683342_4	1115632.JAFW01000001_gene2482	2.164e-64	227.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
MMS1_k127_1683342_5	525909.Afer_0067	9.917e-20	90.0	COG2963@1|root,COG2963@2|Bacteria,2IPC7@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
MMS1_k127_169808_3	525909.Afer_0205	2.941e-09	69.0	COG0433@1|root,COG0433@2|Bacteria,2I2FI@201174|Actinobacteria,4CNRI@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
MMS1_k127_169808_2	1121877.JQKF01000025_gene833	9.122e-32	126.0	2E3QT@1|root,31FNG@2|Bacteria,2HGTF@201174|Actinobacteria,4CNV3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_169808_1	1229780.BN381_30043	1.042e-69	249.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,3UWMA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
MMS1_k127_169808_0	1313172.YM304_07750	3.289e-81	280.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS1_k127_1708942_4	525909.Afer_1134	5.072e-08	57.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4CNBA@84992|Acidimicrobiia	84992|Acidimicrobiia	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
MMS1_k127_1708942_1	545276.KB898724_gene1906	1.34e-65	235.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1WW40@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS1_k127_1708942_3	258052.JNYV01000003_gene4574	1.245e-14	81.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,2M2NZ@2063|Kitasatospora	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
MMS1_k127_1708942_2	525909.Afer_1132	1.959e-41	164.0	COG1994@1|root,COG1994@2|Bacteria,2GM8E@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase M50	rip2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
MMS1_k127_1708942_0	1348338.ADILRU_1946	2.065e-90	303.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FM0U@85023|Microbacteriaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.60,1.2.1.8	ko:K00130,ko:K00151	ko00260,ko00350,ko01100,ko01120,ko01220,map00260,map00350,map01100,map01120,map01220	M00533,M00555	R02565,R02566,R04418	RC00080,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS1_k127_1756385_1	1313172.YM304_33890	3.501e-45	175.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria	201174|Actinobacteria	S	Esterase	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
MMS1_k127_1756385_3	1313172.YM304_12650	4.415e-30	124.0	COG3255@1|root,COG3255@2|Bacteria,2HGCC@201174|Actinobacteria,4CNAG@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1756385_0	1121877.JQKF01000003_gene1467	3.945e-88	316.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CNMC@84992|Acidimicrobiia	84992|Acidimicrobiia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	PASTA,Pkinase
MMS1_k127_1756385_2	1128421.JAGA01000002_gene1815	2.344e-35	141.0	COG0272@1|root,COG0272@2|Bacteria,2NNSW@2323|unclassified Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMS1_k127_1758342_3	435838.HMPREF0786_00221	1.487e-06	57.0	COG0584@1|root,COG0584@2|Bacteria,1TQ3Y@1239|Firmicutes,4HAI9@91061|Bacilli,4GX6I@90964|Staphylococcaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
MMS1_k127_1758342_1	1121877.JQKF01000016_gene168	7.774e-110	374.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CMRV@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Histidine kinase	-	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2
MMS1_k127_1758342_0	525909.Afer_0351	1.368e-115	378.0	COG1387@1|root,COG1387@2|Bacteria,2IR14@201174|Actinobacteria,4CNF5@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Histidinol phosphate phosphatase, HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
MMS1_k127_1758342_2	1229780.BN381_310066	8.806e-92	310.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria	201174|Actinobacteria	D	anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
MMS1_k127_175927_0	1476876.JOJO01000030_gene3181	1.164e-100	338.0	COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
MMS1_k127_175927_1	1121877.JQKF01000038_gene1819	3.02e-97	330.0	COG0451@1|root,COG0451@2|Bacteria,2GP01@201174|Actinobacteria	201174|Actinobacteria	GM	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS1_k127_175927_2	118168.MC7420_634	1.022e-13	73.0	COG2114@1|root,COG2202@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,1G3XH@1117|Cyanobacteria,1H73M@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,Guanylate_cyc,HATPase_c,HisKA,PAS,PAS_4,Response_reg
MMS1_k127_1759670_0	1463887.KL589973_gene1372	4.765e-57	206.0	COG4291@1|root,COG4291@2|Bacteria,2GIW8@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
MMS1_k127_1759670_2	751945.Theos_1825	3.401e-18	97.0	COG0500@1|root,COG2226@2|Bacteria,1WJ5U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS1_k127_1759670_1	1121877.JQKF01000038_gene1821	1.681e-40	167.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CNA1@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
MMS1_k127_1776585_3	1449976.KALB_4230	1.853e-21	98.0	COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria,4E4AM@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
MMS1_k127_1776585_1	350054.Mflv_4204	1.119e-48	179.0	COG2801@1|root,COG2801@2|Bacteria,2HBU8@201174|Actinobacteria,236HP@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM Integrase, catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
MMS1_k127_1776585_0	1121877.JQKF01000002_gene1700	0.0	1273.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
MMS1_k127_1776585_2	1121877.JQKF01000002_gene1699	3.289e-48	179.0	COG0463@1|root,COG0463@2|Bacteria,2GM44@201174|Actinobacteria,4CNK5@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS1_k127_1786095_2	1382306.JNIM01000001_gene2642	7.838e-53	197.0	COG0672@1|root,COG0672@2|Bacteria	2|Bacteria	P	high-affinity ferrous iron transmembrane transporter activity	efeU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1,Peptidase_M75
MMS1_k127_1786095_1	408672.NBCG_04207	6.36e-111	378.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,4DNC6@85009|Propionibacteriales	201174|Actinobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
MMS1_k127_1786095_0	525909.Afer_1296	2.319e-298	924.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CMUT@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
MMS1_k127_1786095_4	1121877.JQKF01000022_gene2300	7.812e-21	94.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4CNBN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
MMS1_k127_1786095_3	1246995.AFR_04305	7.619e-52	209.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1786095_5	1144305.PMI02_03816	3.09e-07	55.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2K2DM@204457|Sphingomonadales	204457|Sphingomonadales	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
MMS1_k127_1788304_1	1304888.ATWF01000002_gene31	1.052e-38	154.0	COG1192@1|root,COG1192@2|Bacteria,2GGAI@200930|Deferribacteres	200930|Deferribacteres	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
MMS1_k127_1788304_3	290315.Clim_1269	5.138e-07	63.0	COG5607@1|root,COG5607@2|Bacteria,1FEUG@1090|Chlorobi	1090|Chlorobi	S	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
MMS1_k127_1788304_0	929712.KI912613_gene2249	4.724e-65	240.0	COG0420@1|root,COG0420@2|Bacteria,2HPQA@201174|Actinobacteria,4CR36@84995|Rubrobacteria	84995|Rubrobacteria	L	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
MMS1_k127_1788304_2	1242864.D187_001519	7.69e-13	83.0	COG0419@1|root,COG4717@1|root,COG0419@2|Bacteria,COG4717@2|Bacteria,1MVAW@1224|Proteobacteria,42MYC@68525|delta/epsilon subdivisions,2WJXA@28221|Deltaproteobacteria,2Z2A3@29|Myxococcales	28221|Deltaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_27
MMS1_k127_1808940_0	1121877.JQKF01000022_gene2267	0.0	1239.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4CMX0@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS1_k127_1808940_2	1229780.BN381_300043	3.545e-18	95.0	COG5012@1|root,COG5012@2|Bacteria,2GKAY@201174|Actinobacteria	201174|Actinobacteria	S	Cobalamin B12-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
MMS1_k127_1808940_1	1229780.BN381_330110	2.873e-110	368.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,3UWAA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
MMS1_k127_1818659_9	926554.KI912652_gene4108	0.0003521	45.0	COG0613@1|root,COG0613@2|Bacteria,1WM4D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
MMS1_k127_1818659_0	1121877.JQKF01000003_gene1456	5.411e-147	478.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4CMSI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS1_k127_1818659_7	1385519.N801_03150	8.485e-23	107.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4FHSS@85021|Intrasporangiaceae	201174|Actinobacteria	S	FmdB family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS1_k127_1818659_2	1229780.BN381_90066	4.124e-106	353.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria,3UWE1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS1_k127_1818659_3	1121877.JQKF01000013_gene290	2.078e-99	338.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4CMP8@84992|Acidimicrobiia	84992|Acidimicrobiia	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
MMS1_k127_1818659_1	1313172.YM304_11040	1.438e-127	416.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4CMV8@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
MMS1_k127_1818659_6	525909.Afer_1854	2.209e-80	270.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CMYS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
MMS1_k127_1818659_4	35754.JNYJ01000078_gene7855	4.601e-88	297.0	COG1028@1|root,COG1028@2|Bacteria,2I9YJ@201174|Actinobacteria,4DHIC@85008|Micromonosporales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
MMS1_k127_1818659_5	467200.ACFA01000004_gene1804	3.179e-81	278.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
MMS1_k127_1818659_8	1380393.JHVP01000014_gene4764	3.578e-06	49.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ES16@85013|Frankiales	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS1_k127_1819760_14	525909.Afer_1971	5.61e-62	238.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,2HG1R@201174|Actinobacteria,4CMYI@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
MMS1_k127_1819760_15	710111.FraQA3DRAFT_2107	1.268e-05	57.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,Methyltransf_11,Methyltransf_23
MMS1_k127_1819760_2	1121877.JQKF01000006_gene942	1.624e-194	632.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS1_k127_1819760_7	1121877.JQKF01000006_gene943	2.241e-126	414.0	COG1609@1|root,COG1609@2|Bacteria,2HF8N@201174|Actinobacteria,4CNUU@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Periplasmic binding protein domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
MMS1_k127_1819760_6	285535.JOEY01000038_gene2767	1.636e-127	418.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Hydrolase_4
MMS1_k127_1819760_8	1121877.JQKF01000006_gene945	3.96e-121	398.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4CNXT@84992|Acidimicrobiia	84992|Acidimicrobiia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
MMS1_k127_1819760_5	1449353.JQMQ01000004_gene5925	6.37e-132	434.0	COG0683@1|root,COG0683@2|Bacteria,2HERM@201174|Actinobacteria,2NFKM@228398|Streptacidiphilus	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMS1_k127_1819760_9	1449353.JQMQ01000004_gene5926	1.882e-102	340.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,2NIFA@228398|Streptacidiphilus	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMS1_k127_1819760_11	1121877.JQKF01000006_gene948	1.252e-94	321.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4CNYD@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMS1_k127_1819760_12	1121877.JQKF01000006_gene949	2.08e-94	324.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CMZ8@84992|Acidimicrobiia	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
MMS1_k127_1819760_10	1121877.JQKF01000006_gene950	1.853e-101	336.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CN2Y@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
MMS1_k127_1819760_13	1121877.JQKF01000006_gene951	3.335e-62	226.0	COG2159@1|root,COG2159@2|Bacteria,2HEB4@201174|Actinobacteria	201174|Actinobacteria	CH	amidohydrolase	-	-	4.1.1.103,4.1.1.45,4.1.1.46,4.1.1.52	ko:K03392,ko:K07045,ko:K14333,ko:K20941,ko:K22213	ko00362,ko00380,ko00627,ko01100,ko01120,map00362,map00380,map00627,map01100,map01120	M00038	R00821,R04323,R11353	RC00390,RC00569,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
MMS1_k127_1819760_0	1121877.JQKF01000006_gene952	1.064e-232	723.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
MMS1_k127_1819760_3	1121877.JQKF01000006_gene953	2.683e-158	505.0	COG1071@1|root,COG1071@2|Bacteria,2HFTJ@201174|Actinobacteria,4CNQW@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
MMS1_k127_1819760_4	1172188.KB911828_gene4081	2.397e-141	464.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4FIX9@85021|Intrasporangiaceae	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMS1_k127_1819760_1	196162.Noca_4473	1.496e-220	692.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DPE3@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS1_k127_1829000_5	1229780.BN381_330016	1.617e-19	91.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
MMS1_k127_1829000_2	1121877.JQKF01000004_gene1074	3.651e-26	115.0	COG1399@1|root,COG1399@2|Bacteria,2HGH0@201174|Actinobacteria,4CNEE@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
MMS1_k127_1829000_4	67275.JOAP01000028_gene202	1.459e-20	98.0	COG0711@1|root,COG0711@2|Bacteria,2GNBF@201174|Actinobacteria	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1829000_0	525909.Afer_1514	1.294e-62	218.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CN4E@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS1_k127_1829000_1	194439.CT0964	1.552e-27	120.0	COG0742@1|root,COG0742@2|Bacteria,1FE59@1090|Chlorobi	1090|Chlorobi	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
MMS1_k127_1829000_3	1121877.JQKF01000004_gene1078	4.086e-24	105.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CMPC@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
MMS1_k127_1857426_8	110662.Syncc9605_1319	1.502e-05	48.0	COG0637@1|root,COG0637@2|Bacteria,1G2T2@1117|Cyanobacteria,1GZ2D@1129|Synechococcus	1117|Cyanobacteria	S	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS1_k127_1857426_5	1121877.JQKF01000033_gene2024	2.406e-52	197.0	COG3409@1|root,COG3409@2|Bacteria,2HGVD@201174|Actinobacteria,4CNW7@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Transglycosylase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglycosylas
MMS1_k127_1857426_3	235985.BBPN01000014_gene5440	1.829e-90	307.0	COG0580@1|root,COG0580@2|Bacteria,2IG6C@201174|Actinobacteria,2NIZF@228398|Streptacidiphilus	201174|Actinobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
MMS1_k127_1857426_0	562970.Btus_1730	5.224e-227	713.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,2793Y@186823|Alicyclobacillaceae	91061|Bacilli	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
MMS1_k127_1857426_2	1121422.AUMW01000020_gene1757	1.096e-96	336.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes	1239|Firmicutes	IQ	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS1_k127_1857426_1	867903.ThesuDRAFT_01010	5.923e-130	428.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WCDK@538999|Clostridiales incertae sedis	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_1857426_7	525909.Afer_0299	9.434e-40	158.0	COG4227@1|root,COG4227@2|Bacteria,2I2PD@201174|Actinobacteria,4CNSA@84992|Acidimicrobiia	84992|Acidimicrobiia	L	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
MMS1_k127_1857426_6	219305.MCAG_03266	5.125e-41	154.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4DFRP@85008|Micromonosporales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
MMS1_k127_1857426_4	66377.JOBH01000011_gene2209	2.641e-88	299.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
MMS1_k127_1898480_1	1121877.JQKF01000003_gene1501	2.394e-118	394.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CMR2@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
MMS1_k127_1898480_3	525909.Afer_1782	6.602e-58	220.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,MFS_1,MFS_3,PP-binding,Thioesterase
MMS1_k127_1898480_4	1313172.YM304_10710	1.889e-46	191.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2HF92@201174|Actinobacteria,4CNT6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
MMS1_k127_1898480_2	1343740.M271_01805	6.019e-69	245.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	garR	-	1.1.1.31,1.1.1.411,1.1.1.60	ko:K00020,ko:K00042,ko:K08319	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMS1_k127_1898480_5	287986.DV20_04745	4.393e-41	157.0	COG1733@1|root,COG1733@2|Bacteria,2GMQG@201174|Actinobacteria,4E3G4@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
MMS1_k127_1898480_0	1206732.BAGD01000043_gene1415	8.98e-164	537.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4FV2M@85025|Nocardiaceae	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
MMS1_k127_19346_7	1121877.JQKF01000002_gene1651	1.689e-14	74.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CMY7@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMS1_k127_19346_2	525909.Afer_1218	5.982e-45	169.0	COG1225@1|root,COG1225@2|Bacteria,2IJVV@201174|Actinobacteria,4CN6R@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS1_k127_19346_3	479431.Namu_3396	4.451e-34	137.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4ESJZ@85013|Frankiales	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
MMS1_k127_19346_4	1112217.PPL19_09857	9.012e-26	114.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
MMS1_k127_19346_0	479437.Elen_0974	1.382e-128	421.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CUPG@84998|Coriobacteriia	84998|Coriobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
MMS1_k127_19346_5	525909.Afer_0046	1.474e-25	115.0	28SZC@1|root,2ZF8S@2|Bacteria,2HBRK@201174|Actinobacteria,4CNUV@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_19346_1	68170.KL590485_gene8363	1.447e-75	260.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4E26W@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS1_k127_19346_6	585531.HMPREF0063_12886	2.55e-19	90.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4DN5F@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS1_k127_1938720_2	1525715.IX54_06475	2.223e-94	316.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,2TSA1@28211|Alphaproteobacteria,2PUIW@265|Paracoccus	28211|Alphaproteobacteria	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
MMS1_k127_1938720_3	266264.Rmet_5045	5.4e-74	259.0	COG0010@1|root,COG0010@2|Bacteria,1NCRN@1224|Proteobacteria,2VNBY@28216|Betaproteobacteria,1K6CD@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	hutG	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS1_k127_1938720_4	585529.HMPREF0291_11728	3.45e-49	182.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,22N58@1653|Corynebacteriaceae	201174|Actinobacteria	S	Appr-1'-p processing enzyme	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
MMS1_k127_1938720_0	479432.Sros_1787	1.964e-140	476.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4EFUU@85012|Streptosporangiales	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
MMS1_k127_1938720_5	679197.HMPREF9336_00250	5.097e-44	162.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the P(II) protein family	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
MMS1_k127_1938720_1	298655.KI912266_gene5385	4.983e-135	439.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4ERCB@85013|Frankiales	201174|Actinobacteria	P	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMS1_k127_1941240_3	1121877.JQKF01000028_gene2125	8.171e-60	211.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4CN24@84992|Acidimicrobiia	84992|Acidimicrobiia	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMS1_k127_1941240_0	504728.K649_10090	2.581e-80	276.0	COG2326@1|root,COG2326@2|Bacteria,1WKEJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
MMS1_k127_1941240_9	525909.Afer_0841	3.782e-14	73.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,MaoC_dehydratas,OB_aCoA_assoc
MMS1_k127_1941240_10	43759.JNWK01000007_gene1797	8.517e-13	79.0	COG0789@1|root,COG0789@2|Bacteria,2GKSZ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMS1_k127_1941240_4	1229780.BN381_430047	1.503e-56	205.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,3UWJ4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMS1_k127_1941240_5	1122611.KB904018_gene7033	6.756e-42	170.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4EH22@85012|Streptosporangiales	201174|Actinobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
MMS1_k127_1941240_1	351607.Acel_0145	6.694e-72	259.0	COG2146@1|root,COG2259@1|root,COG2146@2|Bacteria,COG2259@2|Bacteria,2IKSY@201174|Actinobacteria,4ETHF@85013|Frankiales	201174|Actinobacteria	P	PFAM Rieske 2Fe-2S	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	Rieske
MMS1_k127_1941240_12	42256.RradSPS_1234	0.0004386	50.0	COG0746@1|root,COG0746@2|Bacteria,2HPDS@201174|Actinobacteria,4CQRT@84995|Rubrobacteria	84995|Rubrobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
MMS1_k127_1941240_2	1463936.JOJI01000062_gene4935	2.106e-60	227.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
MMS1_k127_1941240_7	525909.Afer_0833	2.253e-37	143.0	2CC1Y@1|root,331E8@2|Bacteria,2HGFA@201174|Actinobacteria,4CNY6@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
MMS1_k127_1941240_11	1206741.BAFX01000195_gene3672	3.065e-12	76.0	COG0596@1|root,COG0596@2|Bacteria,2GMKY@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
MMS1_k127_1941240_8	105422.BBPM01000007_gene6605	8.606e-17	91.0	COG0697@1|root,COG0697@2|Bacteria,2GRXH@201174|Actinobacteria,2NH1Y@228398|Streptacidiphilus	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1941240_6	298654.FraEuI1c_3799	2.173e-37	148.0	COG0707@1|root,COG0707@2|Bacteria,2GREI@201174|Actinobacteria,4EWT3@85013|Frankiales	201174|Actinobacteria	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glyco_trans_1_4,MGDG_synth
MMS1_k127_194336_0	292.DM42_910	1.456e-107	364.0	28MGB@1|root,2ZATK@2|Bacteria,1R4PG@1224|Proteobacteria,2VZY0@28216|Betaproteobacteria,1KDDF@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_194336_2	1340434.AXVA01000012_gene3017	5.906e-18	98.0	2F3T7@1|root,33WJM@2|Bacteria,1VWCR@1239|Firmicutes,4HWJG@91061|Bacilli,1ZG2R@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_194336_1	1144275.COCOR_03669	3.536e-59	228.0	COG1401@1|root,COG1401@2|Bacteria,1NX8Q@1224|Proteobacteria,42UEK@68525|delta/epsilon subdivisions,2WRQ1@28221|Deltaproteobacteria,2YUGX@29|Myxococcales	28221|Deltaproteobacteria	LV	GTPase subunit of restriction	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_1954107_1	525909.Afer_1960	4.171e-263	813.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CMVI@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
MMS1_k127_1954107_2	1304275.C41B8_15260	1.663e-84	285.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,1RNCX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
MMS1_k127_1954107_6	326424.FRAAL1809	0.000224	53.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	pyr6	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
MMS1_k127_1954107_4	525909.Afer_0050	2.691e-40	158.0	COG4315@1|root,COG4315@2|Bacteria,2HGNM@201174|Actinobacteria,4CNQ2@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
MMS1_k127_1954107_5	1229780.BN381_60087	1.689e-27	116.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	GGDEF,HTH_Crp_2,cNMP_binding
MMS1_k127_1954107_3	1229780.BN381_60056	2.285e-40	156.0	COG1670@1|root,COG1670@2|Bacteria,2IS6V@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS1_k127_1954107_0	1121877.JQKF01000007_gene967	2.578e-292	910.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4CMWD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
MMS1_k127_1955408_1	1122604.JONR01000018_gene1097	9.067e-74	253.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1X3SP@135614|Xanthomonadales	135614|Xanthomonadales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMS1_k127_1955408_0	886293.Sinac_6659	1.933e-207	680.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,2IX0I@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
MMS1_k127_1973654_3	479435.Kfla_4843	1.667e-74	261.0	COG0626@1|root,COG0626@2|Bacteria,2GMD8@201174|Actinobacteria,4DPBS@85009|Propionibacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS1_k127_1973654_2	1206729.BAFZ01000165_gene5664	2.818e-81	281.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4FUF1@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS1_k127_1973654_1	525909.Afer_1450	1.138e-122	413.0	COG0493@1|root,COG0716@1|root,COG1146@1|root,COG0493@2|Bacteria,COG0716@2|Bacteria,COG1146@2|Bacteria,2GJ0A@201174|Actinobacteria,4CNNR@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
MMS1_k127_1973654_0	1121877.JQKF01000015_gene80	8.554e-181	580.0	COG0348@1|root,COG0348@2|Bacteria,2HGM0@201174|Actinobacteria,4CNIT@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
MMS1_k127_1973654_4	1121877.JQKF01000015_gene79	6.366e-42	159.0	COG1959@1|root,COG1959@2|Bacteria,2GS0E@201174|Actinobacteria,4CNRF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMS1_k127_1973654_5	553207.HMPREF0299_7524	7.366e-25	105.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,22JNG@1653|Corynebacteriaceae	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
MMS1_k127_1974921_4	926561.KB900617_gene1489	1.798e-73	256.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3WA6K@53433|Halanaerobiales	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMS1_k127_1974921_2	419947.MRA_0942	1.703e-109	366.0	COG0226@1|root,COG0226@2|Bacteria,2IDU5@201174|Actinobacteria,23CM7@1762|Mycobacteriaceae	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS1	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015698,GO:0016020,GO:0016036,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042301,GO:0042594,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071496,GO:0071944	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMS1_k127_1974921_1	487521.OCU_40930	2.343e-110	368.0	COG0573@1|root,COG0573@2|Bacteria,2ISS5@201174|Actinobacteria,23CM1@1762|Mycobacteriaceae	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS1_k127_1974921_3	487521.OCU_40940	7.051e-87	300.0	COG0581@1|root,COG0581@2|Bacteria,2H3XE@201174|Actinobacteria,23D51@1762|Mycobacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	pstA2	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS1_k127_1974921_0	1313172.YM304_21340	7.612e-133	436.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4CMPZ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
MMS1_k127_1994996_5	525909.Afer_0627	1.32e-88	300.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CMXN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
MMS1_k127_1994996_4	1121877.JQKF01000004_gene1133	4.474e-91	306.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CMRF@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
MMS1_k127_1994996_7	1313172.YM304_27460	3.3e-54	196.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CN2Z@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
MMS1_k127_1994996_6	1121877.JQKF01000004_gene1131	7.768e-56	214.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4CN3S@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
MMS1_k127_1994996_1	1229780.BN381_330056	2.496e-116	387.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,3UWAE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
MMS1_k127_1994996_2	525909.Afer_0632	1.007e-113	381.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CMZX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
MMS1_k127_1994996_0	525909.Afer_0633	7.244e-190	600.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CMRA@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
MMS1_k127_1994996_3	525909.Afer_0634	5.789e-95	321.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CMX4@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Aminoacyl-tRNA editing domain	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
MMS1_k127_2011324_4	1229780.BN381_310066	4.591e-19	89.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria	201174|Actinobacteria	D	anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
MMS1_k127_2011324_1	1229780.BN381_310065	5.652e-86	295.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria	201174|Actinobacteria	D	Pfam Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
MMS1_k127_2011324_6	58123.JOFJ01000005_gene1558	1.487e-07	61.0	COG2864@1|root,COG2864@2|Bacteria,2GNYK@201174|Actinobacteria	201174|Actinobacteria	C	Prokaryotic cytochrome b561	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
MMS1_k127_2011324_3	1214242.B446_08695	1.248e-48	183.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria	201174|Actinobacteria	M	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
MMS1_k127_2011324_2	1121877.JQKF01000011_gene424	3.587e-54	207.0	COG2755@1|root,COG2755@2|Bacteria,2GYQF@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMS1_k127_2011324_0	525909.Afer_0347	1.606e-111	372.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4CMV4@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
MMS1_k127_2014421_3	1121380.JNIW01000064_gene951	8.102e-60	216.0	COG2301@1|root,COG2301@2|Bacteria	2|Bacteria	G	Belongs to the HpcH HpaI aldolase family	citE	GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046872,GO:0071704	4.1.3.25,4.1.3.34	ko:K01644,ko:K18292	ko00660,ko01100,ko02020,map00660,map01100,map02020	-	R00237,R00362	RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS12480,iSFxv_1172.SFxv_0589	HpcH_HpaI
MMS1_k127_2014421_2	1037409.BJ6T_15770	4.031e-68	245.0	COG1335@1|root,COG1335@2|Bacteria,1NZJ1@1224|Proteobacteria,2TV8X@28211|Alphaproteobacteria,3JXI8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
MMS1_k127_2014421_0	675635.Psed_4175	1.132e-97	329.0	COG0726@1|root,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria,4E3UJ@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS1_k127_2014421_4	1121946.AUAX01000023_gene4183	3.337e-12	76.0	2EB5Z@1|root,3356Q@2|Bacteria,2IBJM@201174|Actinobacteria,4DBBN@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2014421_1	525909.Afer_1990	8.056e-75	258.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CNDB@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
MMS1_k127_2016446_4	1273125.Rrhod_3523	1.01e-10	65.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4FUS0@85025|Nocardiaceae	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034355,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
MMS1_k127_2016446_1	1121877.JQKF01000003_gene1472	3.174e-92	310.0	COG0682@1|root,COG0682@2|Bacteria,2HGGR@201174|Actinobacteria,4CNDX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
MMS1_k127_2016446_2	439235.Dalk_0528	1.44e-79	273.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,42S4A@68525|delta/epsilon subdivisions,2WNE7@28221|Deltaproteobacteria,2MNNY@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
MMS1_k127_2016446_0	637390.AFOH01000047_gene2001	2.922e-124	416.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,2NCMW@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
MMS1_k127_2016446_3	469383.Cwoe_0785	9.518e-76	265.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CRRX@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
MMS1_k127_2016446_5	196162.Noca_3124	1.476e-08	57.0	COG0791@1|root,COG1196@1|root,COG0791@2|Bacteria,COG1196@2|Bacteria,2GIWB@201174|Actinobacteria,4DQU1@85009|Propionibacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
MMS1_k127_2024053_0	1146883.BLASA_4626	3.867e-186	595.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EUG9@85013|Frankiales	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	fadD13_1	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_2024053_1	83332.Rv0230c	5.515e-130	422.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria,2360H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phosphotriesterase	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
MMS1_k127_2024053_2	1394178.AWOO02000085_gene993	2.707e-43	173.0	COG1216@1|root,COG1216@2|Bacteria,2I176@201174|Actinobacteria,4EM9E@85012|Streptosporangiales	201174|Actinobacteria	S	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS1_k127_2030158_6	40571.JOEA01000015_gene172	3.301e-14	74.0	COG1831@1|root,COG1831@2|Bacteria,2GM9F@201174|Actinobacteria,4DZYC@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2030158_4	1869.MB27_21925	5.618e-25	108.0	COG3795@1|root,COG3795@2|Bacteria,2IKXM@201174|Actinobacteria,4DE0G@85008|Micromonosporales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMS1_k127_2030158_5	330084.JNYZ01000029_gene94	1.805e-17	89.0	2BWPS@1|root,345TK@2|Bacteria,2H99A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2030158_3	330084.JNYZ01000029_gene94	3.711e-37	143.0	2BWPS@1|root,345TK@2|Bacteria,2H99A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2030158_1	105422.BBPM01000014_gene3231	3.805e-78	271.0	COG1668@1|root,COG1668@2|Bacteria,2GQE9@201174|Actinobacteria,2NKHU@228398|Streptacidiphilus	201174|Actinobacteria	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS1_k127_2030158_0	105422.BBPM01000014_gene3232	2.756e-120	403.0	COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria,2NKKH@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS1_k127_2030158_2	697303.Thewi_2496	2.607e-56	209.0	COG0249@1|root,COG0249@2|Bacteria,1UYBJ@1239|Firmicutes,249T9@186801|Clostridia,42HQ4@68295|Thermoanaerobacterales	186801|Clostridia	L	SMART DNA mismatch repair protein MutS, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
MMS1_k127_203186_7	1206731.BAGB01000148_gene4079	5.537e-29	119.0	COG2169@1|root,COG2169@2|Bacteria,2IQMA@201174|Actinobacteria,4G3ZH@85025|Nocardiaceae	201174|Actinobacteria	F	Metal binding domain of Ada	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding
MMS1_k127_203186_8	1449347.JQLN01000001_gene515	5.236e-21	102.0	2E39M@1|root,32Y96@2|Bacteria,2IITE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_203186_4	1121877.JQKF01000009_gene593	2.771e-61	214.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4CN73@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Nickel-containing superoxide dismutase	sodN	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
MMS1_k127_203186_10	479432.Sros_8300	4.96e-12	77.0	COG0681@1|root,COG0681@2|Bacteria,2IFS4@201174|Actinobacteria,4EKR1@85012|Streptosporangiales	201174|Actinobacteria	U	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
MMS1_k127_203186_9	405948.SACE_7115	6.35e-14	79.0	2DP8R@1|root,32UKH@2|Bacteria,2IFBP@201174|Actinobacteria,4E378@85010|Pseudonocardiales	201174|Actinobacteria	-	-	amfC	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_203186_2	1313172.YM304_37900	2.109e-95	326.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4CMYV@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_203186_6	1206731.BAGB01000068_gene6999	3.762e-48	182.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4FVV6@85025|Nocardiaceae	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
MMS1_k127_203186_11	1540221.JQNI01000002_gene2535	0.0001366	53.0	COG1648@1|root,COG1648@2|Bacteria	2|Bacteria	H	precorrin-2 dehydrogenase activity	cysG	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.76,2.1.1.107,2.1.1.131,3.7.1.12,4.99.1.4	ko:K02302,ko:K02303,ko:K02304,ko:K13541	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947,R05180,R05809,R07772	RC00003,RC00871,RC01012,RC01034,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iJN746.PP_3999,iPC815.YPO0158	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
MMS1_k127_203186_5	1121877.JQKF01000009_gene589	1.468e-57	216.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CN61@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
MMS1_k127_203186_3	1121877.JQKF01000009_gene588	7.787e-70	252.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4CN1F@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
MMS1_k127_203186_1	525909.Afer_0251	5.787e-120	404.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GK3B@201174|Actinobacteria,4CMZM@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
MMS1_k127_203186_0	1313172.YM304_37800	1.268e-121	398.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4CMV9@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
MMS1_k127_2032873_4	1313172.YM304_22710	1.147e-126	415.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CMW2@84992|Acidimicrobiia	84992|Acidimicrobiia	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
MMS1_k127_2032873_11	1313172.YM304_22730	2.104e-25	116.0	COG0354@1|root,COG0354@2|Bacteria,2HGHB@201174|Actinobacteria,4CNEP@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Aminomethyltransferase folate-binding domain	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T
MMS1_k127_2032873_8	494419.ALPM01000054_gene2794	1.81e-54	201.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,1W89R@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
MMS1_k127_2032873_7	525909.Afer_1096	1.783e-61	220.0	COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4CN2A@84992|Acidimicrobiia	84992|Acidimicrobiia	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
MMS1_k127_2032873_2	1121877.JQKF01000021_gene2208	3.717e-162	532.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4CMR9@84992|Acidimicrobiia	84992|Acidimicrobiia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS1_k127_2032873_5	1313172.YM304_24320	7.279e-77	265.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4CMZW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
MMS1_k127_2032873_9	58123.JOFJ01000014_gene5034	2.813e-49	185.0	29JD5@1|root,306AN@2|Bacteria,2I9J8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2032873_14	926569.ANT_17870	9.549e-05	48.0	COG0298@1|root,COG0298@2|Bacteria,2G7GW@200795|Chloroflexi	200795|Chloroflexi	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
MMS1_k127_2032873_13	123214.PERMA_0845	4.163e-10	70.0	COG0068@1|root,COG0068@2|Bacteria,2G3JK@200783|Aquificae	200783|Aquificae	O	Belongs to the carbamoyltransferase HypF family	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,zf-HYPF
MMS1_k127_2032873_10	944547.ABLL_1906	1.06e-33	136.0	COG0680@1|root,COG0680@2|Bacteria,1N3AS@1224|Proteobacteria,43AZK@68525|delta/epsilon subdivisions,2YP7W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
MMS1_k127_2032873_6	123214.PERMA_0697	6.496e-73	253.0	COG1969@1|root,COG1969@2|Bacteria,2G49X@200783|Aquificae	200783|Aquificae	C	Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
MMS1_k127_2032873_0	478741.JAFS01000001_gene2056	4.348e-260	812.0	COG0374@1|root,COG0374@2|Bacteria,46UEU@74201|Verrucomicrobia,37GFV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
MMS1_k127_2032873_3	1249480.B649_09620	5.418e-154	498.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2YMAS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Small subunit	hydA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
MMS1_k127_2032873_12	1123489.AUAN01000006_gene1766	2.399e-11	69.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,4H581@909932|Negativicutes	909932|Negativicutes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
MMS1_k127_2032873_1	1121877.JQKF01000021_gene2202	2.498e-213	674.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMUC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
MMS1_k127_2038410_3	216594.MMAR_4512	4.417e-54	196.0	COG0388@1|root,COG0388@2|Bacteria,2IFF1@201174|Actinobacteria,239QM@1762|Mycobacteriaceae	201174|Actinobacteria	S	hydrolytic enzyme probably involved in cellular metabolism	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
MMS1_k127_2038410_2	521096.Tpau_2797	8.222e-81	278.0	COG1305@1|root,COG1305@2|Bacteria,2GN5D@201174|Actinobacteria	201174|Actinobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
MMS1_k127_2038410_1	543632.JOJL01000037_gene6473	2.063e-83	289.0	COG2307@1|root,COG2307@2|Bacteria,2GN0T@201174|Actinobacteria,4DC5X@85008|Micromonosporales	201174|Actinobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
MMS1_k127_2038410_0	222534.KB893783_gene5275	8.271e-93	311.0	COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4ES9X@85013|Frankiales	201174|Actinobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2
MMS1_k127_2054673_1	525909.Afer_1286	2.577e-78	263.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CMRX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS1_k127_2054673_4	1463856.JOHY01000001_gene525	9.917e-61	216.0	COG1584@1|root,COG1584@2|Bacteria,2IIIX@201174|Actinobacteria	201174|Actinobacteria	S	PFAM GPR1 FUN34 yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
MMS1_k127_2054673_2	1313172.YM304_21150	3.981e-76	270.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CNTM@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS1_k127_2054673_6	1121877.JQKF01000022_gene2296	1.097e-48	180.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria,4CN5U@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMS1_k127_2054673_7	195105.CN97_10165	4.476e-13	78.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
MMS1_k127_2054673_0	1121877.JQKF01000022_gene2298	2.875e-128	420.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CMQ3@84992|Acidimicrobiia	84992|Acidimicrobiia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS1_k127_2054673_3	1313172.YM304_21110	2.226e-71	256.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CN2R@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
MMS1_k127_2054673_5	1121946.AUAX01000029_gene1996	2.893e-51	194.0	COG0463@1|root,COG2244@1|root,COG0463@2|Bacteria,COG2244@2|Bacteria,2I7M5@201174|Actinobacteria,4DFBM@85008|Micromonosporales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Polysacc_synt_3
MMS1_k127_2056953_1	1283287.KB822578_gene2324	3.43e-125	409.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4DV93@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMS1_k127_2056953_3	1283287.KB822578_gene2323	2.171e-110	362.0	COG1878@1|root,COG1878@2|Bacteria,2GUSA@201174|Actinobacteria	201174|Actinobacteria	S	cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMS1_k127_2056953_0	263358.VAB18032_20655	7.526e-184	582.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4D936@85008|Micromonosporales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
MMS1_k127_2056953_5	1283287.KB822578_gene2328	1.465e-94	326.0	COG2079@1|root,COG2079@2|Bacteria,2I8CW@201174|Actinobacteria	201174|Actinobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMS1_k127_2056953_6	2002.JOEQ01000005_gene3805	5.231e-88	297.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4EP9K@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMS1_k127_2056953_7	675635.Psed_4172	7.871e-81	283.0	COG1879@1|root,COG1879@2|Bacteria,2GNSF@201174|Actinobacteria,4ECTV@85010|Pseudonocardiales	201174|Actinobacteria	P	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
MMS1_k127_2056953_4	1150398.JIBJ01000012_gene2164	1.492e-97	331.0	COG1172@1|root,COG1172@2|Bacteria,2GMJW@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
MMS1_k127_2056953_2	675635.Psed_4171	8.474e-114	386.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4EA8T@85010|Pseudonocardiales	201174|Actinobacteria	G	SMART ATPase, AAA type, core	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
MMS1_k127_2063627_3	1206730.BAGA01000140_gene3393	4.427e-22	103.0	COG1235@1|root,COG2087@1|root,COG1235@2|Bacteria,COG2087@2|Bacteria,2GM8Q@201174|Actinobacteria,4FYZ7@85025|Nocardiaceae	201174|Actinobacteria	H	Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU,Lactamase_B_2
MMS1_k127_2063627_1	1121877.JQKF01000001_gene1429	2.26e-72	252.0	COG2109@1|root,COG2109@2|Bacteria,2GNJQ@201174|Actinobacteria,4CN3K@84992|Acidimicrobiia	84992|Acidimicrobiia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
MMS1_k127_2063627_0	1155718.KB891910_gene1284	3.784e-89	312.0	COG1797@1|root,COG1797@2|Bacteria,2GJ3R@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source	cobB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2,CbiA,GATase_3
MMS1_k127_2063627_2	28042.GU90_09250	8.752e-43	168.0	COG2243@1|root,COG2243@2|Bacteria,2GUI0@201174|Actinobacteria,4EA61@85010|Pseudonocardiales	201174|Actinobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
MMS1_k127_2063627_4	526225.Gobs_3862	1.644e-08	64.0	COG2199@1|root,COG3706@2|Bacteria,2I6MR@201174|Actinobacteria	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMS1_k127_2067548_6	1121877.JQKF01000060_gene1946	2.059e-41	162.0	COG2141@1|root,COG2141@2|Bacteria,2HG01@201174|Actinobacteria,4CNXD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS1_k127_2067548_1	1121877.JQKF01000060_gene1947	2.849e-133	436.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.4,1.3.8.7	ko:K00249,ko:K00253	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_2067548_0	1121877.JQKF01000060_gene1948	3.986e-210	672.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K04116,ko:K12507	ko00362,ko01120,map00362,map01120	M00540	R05620	RC00004,RC01438	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_2067548_3	1121877.JQKF01000060_gene1949	3.552e-129	419.0	COG1024@1|root,COG1024@2|Bacteria,2HG19@201174|Actinobacteria,4CNYE@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS1_k127_2067548_2	1089544.KB912942_gene7287	1.591e-131	431.0	COG1960@1|root,COG1960@2|Bacteria,2GK1M@201174|Actinobacteria,4DZ7D@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_2067548_4	1121877.JQKF01000060_gene1951	9.366e-100	331.0	COG1028@1|root,COG1028@2|Bacteria,2HFKT@201174|Actinobacteria,4CNUQ@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS1_k127_2067548_5	1380390.JIAT01000012_gene3179	1.209e-45	177.0	COG1024@1|root,COG1024@2|Bacteria,2HG16@201174|Actinobacteria,4CTMW@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS1_k127_2081021_0	525909.Afer_1846	2.348e-229	714.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CNG0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMS1_k127_2081021_4	1229780.BN381_150094	1.378e-28	117.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,3UXHU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS1_k127_2081021_1	525909.Afer_1848	3.531e-173	552.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria	201174|Actinobacteria	E	Threonine synthase	thrC3	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS1_k127_2081021_3	1380347.JNII01000007_gene76	1.032e-67	243.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	garK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
MMS1_k127_2081021_2	1896.JOAU01000038_gene2252	6.328e-94	324.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria	201174|Actinobacteria	G	synthase	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
MMS1_k127_2081021_5	1380346.JNIH01000010_gene2943	3.247e-19	98.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
MMS1_k127_2116551_3	351607.Acel_1286	1.025e-60	214.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4ESI6@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
MMS1_k127_2116551_0	525909.Afer_0575	4.581e-237	739.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4CNF6@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
MMS1_k127_2116551_1	1380390.JIAT01000012_gene3163	1.87e-124	416.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CRJZ@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K12429	-	-	-	-	ko00000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_2116551_4	1333998.M2A_2573	5.997e-47	179.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,4BQ72@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase carnithine racemase	-	-	4.1.1.41,4.2.1.17	ko:K01692,ko:K11264	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R00923,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00097,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS1_k127_2116551_2	525909.Afer_0586	3.319e-93	316.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4CNH6@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS1_k127_2124628_6	1313172.YM304_19590	1.719e-15	81.0	COG1959@1|root,COG1959@2|Bacteria,2HG5V@201174|Actinobacteria,4CN2Q@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMS1_k127_2124628_0	1229780.BN381_430074	9.094e-87	302.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,3UWWP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
MMS1_k127_2124628_4	298655.KI912266_gene1470	3.49e-43	162.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4ESN9@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
MMS1_k127_2124628_3	1229780.BN381_80386	7.781e-48	175.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,3UWPM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
MMS1_k127_2124628_2	1121877.JQKF01000038_gene1833	2.287e-51	196.0	COG4188@1|root,COG4188@2|Bacteria,2HGN0@201174|Actinobacteria,4CNNA@84992|Acidimicrobiia	84992|Acidimicrobiia	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2124628_1	1121877.JQKF01000038_gene1832	1.093e-70	254.0	COG0154@1|root,COG0154@2|Bacteria,2GSBS@201174|Actinobacteria,4CNRJ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS1_k127_2124628_5	856793.MICA_1890	7.641e-22	102.0	KOG2524@1|root,2ZJ84@2|Bacteria,1NCHA@1224|Proteobacteria	1224|Proteobacteria	S	Potential Queuosine, Q, salvage protein family	-	-	-	-	-	-	-	-	-	-	-	-	Q_salvage
MMS1_k127_2125918_11	1246995.AFR_04305	0.0009772	47.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2125918_7	1121877.JQKF01000025_gene820	2.402e-46	170.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,4CNSJ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMS1_k127_2125918_5	1121877.JQKF01000025_gene821	3.992e-52	188.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria,4CNSQ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMS1_k127_2125918_0	525909.Afer_0190	2e-163	525.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CMQR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Seryl-tRNA synthetase N-terminal domain	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
MMS1_k127_2125918_3	525909.Afer_0191	2.87e-81	280.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4CNG5@84992|Acidimicrobiia	84992|Acidimicrobiia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS1_k127_2125918_4	525909.Afer_0192	1.609e-61	221.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4CNIF@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS1_k127_2125918_1	1121877.JQKF01000025_gene825	4.514e-103	344.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4CN5J@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
MMS1_k127_2125918_8	2055.JNXA01000001_gene2171	9.594e-29	118.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4GEYN@85026|Gordoniaceae	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
MMS1_k127_2125918_9	28444.JODQ01000011_gene3474	1.576e-16	85.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4EJ1I@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
MMS1_k127_2125918_6	1121272.KB903250_gene2872	1.368e-50	192.0	COG2267@1|root,COG2267@2|Bacteria,2IGKW@201174|Actinobacteria,4DIAN@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
MMS1_k127_2125918_2	1121272.KB903250_gene2873	1.353e-83	292.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2I98G@201174|Actinobacteria,4DA46@85008|Micromonosporales	201174|Actinobacteria	JPQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2134462_5	288000.BBta_0469	9.184e-25	107.0	COG0694@1|root,COG2146@1|root,COG0694@2|Bacteria,COG2146@2|Bacteria,1PEZF@1224|Proteobacteria,2U24J@28211|Alphaproteobacteria,3JU84@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	OP	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU,Rieske
MMS1_k127_2134462_3	350058.Mvan_2370	4.95e-126	414.0	COG3391@1|root,COG3391@2|Bacteria,2GMGG@201174|Actinobacteria,236E8@1762|Mycobacteriaceae	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMS1_k127_2134462_6	1440774.Y900_003905	7.97e-24	102.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria,239ZW@1762|Mycobacteriaceae	201174|Actinobacteria	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
MMS1_k127_2134462_1	309801.trd_1867	5.718e-154	496.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi	200795|Chloroflexi	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
MMS1_k127_2134462_2	1089548.KI783301_gene288	3.49e-127	415.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,4HB74@91061|Bacilli	91061|Bacilli	O	hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
MMS1_k127_2134462_4	35754.JNYJ01000040_gene1508	4.427e-25	108.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4DEW0@85008|Micromonosporales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
MMS1_k127_2134462_0	479434.Sthe_2958	1.179e-178	566.0	COG4447@1|root,COG4447@2|Bacteria,2G5ZD@200795|Chloroflexi	200795|Chloroflexi	S	BNR/Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR
MMS1_k127_2134462_8	298654.FraEuI1c_2450	2.95e-10	70.0	2DF97@1|root,2ZQZA@2|Bacteria	2|Bacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS1_k127_2134462_7	656024.FsymDg_2923	2.901e-10	68.0	2DF97@1|root,2ZQZA@2|Bacteria	2|Bacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS1_k127_2134462_9	1107311.Q767_15620	1.066e-05	55.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
MMS1_k127_2136566_0	1246995.AFR_04305	8.706e-27	110.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2136566_1	1463934.JOCF01000077_gene6520	4.31e-21	104.0	COG0500@1|root,COG2226@2|Bacteria,2H1GK@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS1_k127_2136566_2	1033743.CAES01000049_gene486	0.0009203	51.0	COG4447@1|root,COG4447@2|Bacteria,1V10R@1239|Firmicutes,4IPNU@91061|Bacilli,27614@186822|Paenibacillaceae	91061|Bacilli	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR,Sortilin-Vps10
MMS1_k127_2136753_4	468556.AQYG01000051_gene2449	8.102e-60	216.0	COG1309@1|root,COG1309@2|Bacteria,2IDV2@201174|Actinobacteria,4GBWN@85026|Gordoniaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS1_k127_2136753_2	487521.OCU_46490	2.621e-91	308.0	COG1028@1|root,COG1028@2|Bacteria,2GJW1@201174|Actinobacteria,232H3@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Dehydrogenase	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS1_k127_2136753_0	1206720.BAFQ01000025_gene635	7.46e-238	746.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FV41@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS1_k127_2136753_1	547163.BN979_05017	9.203e-128	414.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,232A4@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA15	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS1_k127_2136753_3	1121877.JQKF01000020_gene2496	7.372e-68	239.0	COG4565@1|root,COG4565@2|Bacteria,2GK16@201174|Actinobacteria,4CNEZ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,Response_reg
MMS1_k127_2138340_0	105420.BBPO01000040_gene803	1.512e-195	615.0	COG0451@1|root,COG0451@2|Bacteria,2GJJG@201174|Actinobacteria,2NKTW@228398|Streptacidiphilus	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	sqdB	-	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	-	Epimerase
MMS1_k127_2138340_2	1121877.JQKF01000010_gene695	2.276e-74	267.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4CN19@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2138340_3	298655.KI912266_gene5278	6.691e-66	229.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4EVCG@85013|Frankiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	gca	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep
MMS1_k127_2138340_1	395019.Bmul_1064	9.288e-127	415.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2VMYU@28216|Betaproteobacteria,1K2AM@119060|Burkholderiaceae	28216|Betaproteobacteria	C	aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
MMS1_k127_2138340_4	350058.Mvan_2087	7.893e-58	211.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,235YF@1762|Mycobacteriaceae	201174|Actinobacteria	P	ABC transporter	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
MMS1_k127_2138340_5	2074.JNYD01000001_gene6185	6.377e-26	120.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,2I2RA@201174|Actinobacteria,4E9MN@85010|Pseudonocardiales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
MMS1_k127_2138426_4	1051632.TPY_3390	1.208e-05	48.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	dpp4	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
MMS1_k127_2138426_1	479434.Sthe_1877	1.455e-68	237.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi,27Y8S@189775|Thermomicrobia	189775|Thermomicrobia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMS1_k127_2138426_0	525909.Afer_0087	1.061e-154	511.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CMUZ@84992|Acidimicrobiia	84992|Acidimicrobiia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
MMS1_k127_2138426_2	1121877.JQKF01000011_gene361	2.139e-27	113.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CMY4@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
MMS1_k127_2140621_2	1313172.YM304_08920	6.589e-54	201.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CN11@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
MMS1_k127_2140621_3	1229780.BN381_130028	4.349e-47	188.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,3UXFU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Carbohydrate kinase	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
MMS1_k127_2140621_4	309801.trd_0814	7.971e-17	87.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi,27YDS@189775|Thermomicrobia	189775|Thermomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
MMS1_k127_2140621_0	319795.Dgeo_2840	1.319e-61	223.0	COG0583@1|root,COG0583@2|Bacteria,1WIJI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS1_k127_2140621_1	1357275.AVEL02000044_gene421	9.69e-61	224.0	COG1275@1|root,COG1275@2|Bacteria,1MXP2@1224|Proteobacteria,1RR76@1236|Gammaproteobacteria,1Z6HE@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	P	C4-dicarboxylate transporter malic acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
MMS1_k127_2144983_0	1121877.JQKF01000016_gene124	2.406e-106	347.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CMRQ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_2144983_1	1283287.KB822575_gene535	3.139e-102	339.0	COG0788@1|root,COG0788@2|Bacteria,2GM0G@201174|Actinobacteria,4DP82@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,ACT_6,Formyl_trans_N
MMS1_k127_2144983_2	1229780.BN381_310040	1.928e-41	162.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,3UWW4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS1_k127_2144983_3	439235.Dalk_2073	2.742e-07	54.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,42RTA@68525|delta/epsilon subdivisions,2WNCA@28221|Deltaproteobacteria,2MMZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS1_k127_215326_0	1121877.JQKF01000027_gene2474	0.0	1416.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CMWT@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA polymerase alpha chain like domain	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
MMS1_k127_215326_1	1120936.KB907209_gene1600	6.218e-154	506.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_215326_2	1007105.PT7_0052	0.0006046	44.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJ63@28216|Betaproteobacteria,3T2FS@506|Alcaligenaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	caiD	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS1_k127_2173931_2	1121877.JQKF01000001_gene1378	9.922e-102	334.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CMUY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS1_k127_2173931_0	525909.Afer_0763	1.882e-195	616.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CMS8@84992|Acidimicrobiia	84992|Acidimicrobiia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
MMS1_k127_2173931_3	1313172.YM304_18330	1.821e-75	269.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CNAR@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
MMS1_k127_2173931_4	525909.Afer_0765	5.138e-46	177.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4CN6F@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
MMS1_k127_2173931_1	1121877.JQKF01000001_gene1382	1.451e-111	363.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS1_k127_2175321_4	1198452.Jab_1c14720	7.117e-27	119.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,2VNHN@28216|Betaproteobacteria,476YE@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	UTRA	-	-	-	ko:K03486,ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
MMS1_k127_2175321_3	1229780.BN381_150047	3.82e-52	188.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,3UWVQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
MMS1_k127_2175321_0	1121877.JQKF01000011_gene377	3.05e-223	699.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4CMSB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Zinc-binding dehydrogenase	-	-	1.3.1.86	ko:K17829	ko00650,ko01120,ko01130,ko01200,map00650,map01120,map01130,map01200	-	R09738	RC00076	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS1_k127_2175321_1	1121877.JQKF01000011_gene378	8.66e-169	539.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTP@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS1_k127_2175321_2	1229780.BN381_150040	9.725e-99	344.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,3UWAK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
MMS1_k127_2179514_9	408672.NBCG_02085	1.11e-06	51.0	COG0626@1|root,COG0626@2|Bacteria,2GMD8@201174|Actinobacteria,4DPBS@85009|Propionibacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS1_k127_2179514_6	1120950.KB892769_gene5386	1.959e-34	138.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4DR0E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
MMS1_k127_2179514_4	525909.Afer_1497	8.618e-52	187.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CN2N@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
MMS1_k127_2179514_2	1313172.YM304_18760	1.419e-82	284.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CMZ9@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
MMS1_k127_2179514_5	1313172.YM304_18750	4.057e-35	140.0	COG0806@1|root,COG0806@2|Bacteria,2HGD9@201174|Actinobacteria,4CNBG@84992|Acidimicrobiia	84992|Acidimicrobiia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	RimM
MMS1_k127_2179514_8	1209989.TepiRe1_1310	1.686e-09	65.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,42H76@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
MMS1_k127_2179514_7	1229780.BN381_330035	1.327e-30	126.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,3UWU1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
MMS1_k127_2179514_0	1121877.JQKF01000047_gene1186	1.458e-168	540.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CMPN@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
MMS1_k127_2179514_1	1313172.YM304_18700	4.403e-93	318.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CMY6@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54
MMS1_k127_2179514_3	1229780.BN381_330023	4.704e-61	231.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,3UWCX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
MMS1_k127_2179868_7	525909.Afer_1723	2.258e-31	126.0	COG0694@1|root,COG0694@2|Bacteria,2HGAJ@201174|Actinobacteria,4CN9Q@84992|Acidimicrobiia	84992|Acidimicrobiia	O	NifU-like domain	-	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	NifU
MMS1_k127_2179868_8	561175.KB894103_gene1317	6.509e-27	116.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4EJU5@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMS1_k127_2179868_1	326424.FRAAL5497	8.305e-127	430.0	COG3266@1|root,COG3266@2|Bacteria,2I302@201174|Actinobacteria,4EUA2@85013|Frankiales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2179868_4	1313172.YM304_37950	5.349e-43	169.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4CNVE@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
MMS1_k127_2179868_3	1454010.JEOE01000001_gene616	3.617e-50	187.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4F1IU@85016|Cellulomonadaceae	201174|Actinobacteria	NOU	Type IV leader peptidase family	pppA	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
MMS1_k127_2179868_13	645127.ckrop_3007	8.057e-09	58.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria,22P4W@1653|Corynebacteriaceae	201174|Actinobacteria	K	DNA binding domain, excisionase family	xis	-	-	-	-	-	-	-	-	-	-	-	HTH_17
MMS1_k127_2179868_9	590998.Celf_1996	3.736e-20	106.0	COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria	201174|Actinobacteria	NU	pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
MMS1_k127_2179868_14	401526.TcarDRAFT_1552	2.943e-05	54.0	COG3167@1|root,COG3167@2|Bacteria,1VHP1@1239|Firmicutes,4H5NS@909932|Negativicutes	909932|Negativicutes	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
MMS1_k127_2179868_0	1121877.JQKF01000024_gene2399	1.276e-174	556.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CMPX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
MMS1_k127_2179868_10	13689.BV96_01563	1.07e-18	94.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,2K4PP@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
MMS1_k127_2179868_2	1229780.BN381_50134	9.604e-90	312.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,3UWGT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829,ko:K16020	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R02412,R03083,R06592	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
MMS1_k127_2179868_6	1229780.BN381_50135	7.911e-39	149.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,3UWWA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786,ko:K16021	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R03084,R06593	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
MMS1_k127_2179868_11	525909.Afer_1715	1.117e-16	88.0	2A6BK@1|root,30V4C@2|Bacteria,2HGQ3@201174|Actinobacteria,4CNSP@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2179868_5	234267.Acid_6266	1.327e-42	162.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
MMS1_k127_2179868_12	330084.JNYZ01000014_gene6241	2.135e-16	85.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4E3S8@85010|Pseudonocardiales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
MMS1_k127_2180375_1	408672.NBCG_04758	2.456e-45	175.0	COG1595@1|root,COG1595@2|Bacteria,2GTCV@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
MMS1_k127_2180375_2	1449976.KALB_3823	6.712e-45	178.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4E8VE@85010|Pseudonocardiales	201174|Actinobacteria	CG	Glycosyltransferase family 28 C-terminal domain	-	-	-	ko:K16039	ko01051,ko01130,map01051,map01130	-	R09857	RC00005,RC02843	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C,UDPGT
MMS1_k127_2180375_0	1121877.JQKF01000009_gene498	5.621e-178	560.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
MMS1_k127_2199254_0	525909.Afer_1141	2.681e-249	783.0	COG0747@1|root,COG0747@2|Bacteria,2GZTR@201174|Actinobacteria,4CNEY@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS1_k127_2199254_1	1313172.YM304_34270	2.264e-102	337.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4CMXQ@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
MMS1_k127_2199254_2	1035308.AQYY01000002_gene110	8.322e-44	171.0	COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,24AXN@186801|Clostridia,262AV@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
MMS1_k127_2199254_3	118161.KB235922_gene3620	9.302e-26	114.0	COG1309@1|root,COG1309@2|Bacteria,1GD6S@1117|Cyanobacteria	1117|Cyanobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
MMS1_k127_2204697_7	246196.MSMEI_1964	1.173e-12	72.0	2ETCD@1|root,33KW9@2|Bacteria,2GWP0@201174|Actinobacteria	201174|Actinobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
MMS1_k127_2204697_6	926560.KE387023_gene2836	5.23e-24	113.0	COG0287@1|root,COG0287@2|Bacteria,1WII2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
MMS1_k127_2204697_4	1121877.JQKF01000029_gene2108	3.938e-73	258.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CNJ6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	PDT
MMS1_k127_2204697_8	471856.Jden_0752	8.764e-12	70.0	COG1396@1|root,COG1396@2|Bacteria,2H1EJ@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMS1_k127_2204697_1	1562701.BBOF01000022_gene685	5.941e-126	421.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2VMN6@28216|Betaproteobacteria,1K4VE@119060|Burkholderiaceae	28216|Betaproteobacteria	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
MMS1_k127_2204697_0	1380356.JNIK01000016_gene3735	1.786e-138	470.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4ERI9@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX2	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
MMS1_k127_2204697_3	134676.ACPL_759	1.24e-104	346.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria,4D93S@85008|Micromonosporales	201174|Actinobacteria	P	Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
MMS1_k127_2204697_5	1380347.JNII01000007_gene292	7.007e-60	222.0	COG1277@1|root,COG1277@2|Bacteria,2GM0N@201174|Actinobacteria,4EVKG@85013|Frankiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS1_k127_2204697_2	1306174.JODP01000009_gene6296	1.7e-117	385.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS1_k127_2207902_2	1121877.JQKF01000009_gene582	3.373e-90	299.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4CMXA@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMS1_k127_2207902_4	1313172.YM304_04080	2.033e-52	189.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CN4G@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
MMS1_k127_2207902_0	1121877.JQKF01000009_gene580	5.901e-221	692.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CMP9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
MMS1_k127_2207902_3	525909.Afer_0367	1.118e-78	268.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4CN1U@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMS1_k127_2207902_1	1121877.JQKF01000009_gene578	3.688e-196	624.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4CMQ2@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S
MMS1_k127_2218794_1	525909.Afer_1061	7.255e-156	503.0	COG0477@1|root,COG2814@2|Bacteria,2I2ZF@201174|Actinobacteria,4CNM3@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2218794_6	604331.AUHY01000009_gene415	1.142e-12	75.0	COG1959@1|root,COG1959@2|Bacteria,1WIBU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Transcriptional regulator, BadM Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMS1_k127_2218794_5	411474.COPEUT_02533	3.61e-21	106.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMS1_k127_2218794_3	941449.dsx2_3360	9.376e-75	283.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,Response_reg,dCache_2
MMS1_k127_2218794_2	1121877.JQKF01000009_gene570	4.864e-115	390.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CMT6@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMS1_k127_2218794_0	1121877.JQKF01000009_gene571	3.167e-166	537.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4CMUB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Protein synonym NADH dehydrogenase I subunit M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMS1_k127_2218794_4	1121877.JQKF01000009_gene572	9.56e-73	254.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4CMPU@84992|Acidimicrobiia	84992|Acidimicrobiia	CP	protein synonym multiple resistance and pH homeostasis protein A	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
MMS1_k127_2223594_1	1236902.ANAS01000040_gene5008	5.906e-75	253.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4EH1A@85012|Streptosporangiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMS1_k127_2223594_0	298654.FraEuI1c_5630	1.564e-86	303.0	COG0277@1|root,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4ESN2@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS1_k127_2223594_3	383372.Rcas_1084	1.161e-63	236.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2223594_5	1192034.CAP_5386	3.186e-09	68.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria,2YW4H@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
MMS1_k127_2223594_4	1211815.CBYP010000061_gene34	1.126e-50	190.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4EVH7@85013|Frankiales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS1_k127_2223594_2	665577.JH993790_gene5529	3.475e-73	255.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria	201174|Actinobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
MMS1_k127_2231172_4	1121877.JQKF01000016_gene157	6.541e-10	64.0	COG2332@1|root,COG2332@2|Bacteria,2GZPB@201174|Actinobacteria,4CNCV@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
MMS1_k127_2231172_1	1121877.JQKF01000016_gene155	1.252e-88	299.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria,4CN1E@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
MMS1_k127_2231172_3	1229780.BN381_310050	1.238e-41	161.0	COG2386@1|root,COG2386@2|Bacteria,2GUCP@201174|Actinobacteria	201174|Actinobacteria	O	heme exporter protein CcmB	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
MMS1_k127_2231172_2	1313172.YM304_09600	1.804e-50	187.0	COG1131@1|root,COG1131@2|Bacteria,2HG8W@201174|Actinobacteria,4CN6P@84992|Acidimicrobiia	84992|Acidimicrobiia	V	ATPases associated with a variety of cellular activities	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
MMS1_k127_2231172_0	357808.RoseRS_3928	4.945e-161	512.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,375CR@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS1_k127_223836_2	1313172.YM304_19760	9.053e-09	58.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4CN56@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
MMS1_k127_223836_0	351607.Acel_1959	1.213e-132	438.0	COG0477@1|root,COG0477@2|Bacteria,2I8QU@201174|Actinobacteria,4ETQP@85013|Frankiales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_223836_1	1313172.YM304_19780	2.198e-50	187.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CN3N@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
MMS1_k127_2279519_2	1221522.B723_15055	2.367e-05	46.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria,1YRNH@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
MMS1_k127_2279519_0	717605.Theco_3116	7.088e-49	196.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,4HDFR@91061|Bacilli,26ZRA@186822|Paenibacillaceae	91061|Bacilli	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
MMS1_k127_2279519_1	1125863.JAFN01000001_gene3206	7.555e-44	168.0	COG2159@1|root,COG2159@2|Bacteria,1QZ3W@1224|Proteobacteria,42PKB@68525|delta/epsilon subdivisions,2WM59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
MMS1_k127_22846_2	323098.Nwi_0553	1.084e-58	211.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2U1D1@28211|Alphaproteobacteria,3JRGI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	haloacid dehalogenase-like hydrolase	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS1_k127_22846_0	1211815.CBYP010000061_gene53	1.032e-183	589.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EUU3@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_22846_1	345341.KUTG_02107	1.135e-62	219.0	COG1960@1|root,COG1960@2|Bacteria,2GVSU@201174|Actinobacteria,4DYFB@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_2286392_2	1121877.JQKF01000018_gene2550	3.351e-93	314.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CNQZ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
MMS1_k127_2286392_0	298654.FraEuI1c_5186	2.352e-147	487.0	COG1178@1|root,COG1178@2|Bacteria,2IN5Y@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
MMS1_k127_2286392_1	436229.JOEH01000045_gene7427	1.245e-134	437.0	COG1840@1|root,COG1840@2|Bacteria,2HN57@201174|Actinobacteria,2NHAS@228398|Streptacidiphilus	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
MMS1_k127_2286392_3	67332.FM21_29860	1.479e-36	146.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
MMS1_k127_2296875_2	525909.Afer_1142	1.411e-99	332.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4CNGS@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS1_k127_2296875_1	525909.Afer_1143	4.032e-108	359.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CN2T@84992|Acidimicrobiia	84992|Acidimicrobiia	U	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS1_k127_2296875_0	525909.Afer_1147	1.896e-291	908.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CP5D@84992|Acidimicrobiia	84992|Acidimicrobiia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMS1_k127_2296875_3	1121946.AUAX01000022_gene3837	5.853e-80	281.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	lpqI	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
MMS1_k127_2296875_4	1382304.JNIL01000001_gene2287	1.954e-08	64.0	COG1287@1|root,COG1287@2|Bacteria,1VT5G@1239|Firmicutes	1239|Firmicutes	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2312436_2	1121877.JQKF01000060_gene1945	1.835e-08	55.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_2312436_0	1121877.JQKF01000060_gene1944	3.537e-86	294.0	COG1309@1|root,COG1309@2|Bacteria,2IDV2@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS1_k127_2312436_1	443152.MDG893_15050	2.527e-74	264.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,1RR4Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Cyclodeaminase	ocd2	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	iJN746.PP_4431	OCD_Mu_crystall
MMS1_k127_2324439_1	525909.Afer_1545	3.649e-153	490.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CMV2@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
MMS1_k127_2324439_2	1121877.JQKF01000003_gene1460	6.387e-58	214.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4CN3W@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
MMS1_k127_2324439_0	1121877.JQKF01000003_gene1461	8.091e-212	665.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CMWQ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS1_k127_2331121_3	1108045.GORHZ_118_00010	3.168e-45	172.0	COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria,4GAY6@85026|Gordoniaceae	201174|Actinobacteria	H	biotin lipoate A B protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
MMS1_k127_2331121_0	1108045.GORHZ_118_00020	1.06e-141	457.0	COG1856@1|root,COG1856@2|Bacteria,2H3RG@201174|Actinobacteria	201174|Actinobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
MMS1_k127_2331121_4	1562701.BBOF01000068_gene2206	2.762e-12	72.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria,1K7VA@119060|Burkholderiaceae	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
MMS1_k127_2331121_2	882083.SacmaDRAFT_1926	2.752e-57	212.0	COG0095@1|root,COG0095@2|Bacteria,2H716@201174|Actinobacteria	201174|Actinobacteria	H	PFAM Biotin lipoate A B protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2331121_1	1121877.JQKF01000008_gene605	7.004e-106	346.0	COG0247@1|root,COG0247@2|Bacteria,2H2WJ@201174|Actinobacteria,4CNGI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_9
MMS1_k127_2331452_2	1957.JODX01000017_gene1856	9.071e-54	192.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
MMS1_k127_2331452_0	882083.SacmaDRAFT_5159	0.0	1448.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DZUH@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMS1_k127_2331452_3	593907.Celgi_0542	4.656e-45	177.0	29YYI@1|root,30KVC@2|Bacteria,2IGN9@201174|Actinobacteria	201174|Actinobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
MMS1_k127_2331452_1	479432.Sros_6336	2.592e-65	227.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4EK0J@85012|Streptosporangiales	201174|Actinobacteria	I	MaoC like domain	-	-	4.2.1.56	ko:K18290	ko00660,map00660	-	R02491	RC00730	ko00000,ko00001,ko01000	-	-	-	MaoC_dehydratas
MMS1_k127_2331452_4	47716.JOFH01000019_gene4945	1.641e-36	139.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_2332565_0	1121877.JQKF01000039_gene1850	1.517e-155	497.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4CMQC@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Alanine dehydrogenase/PNT, N-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
MMS1_k127_2332565_5	1123023.JIAI01000007_gene1977	1.09e-33	143.0	COG1975@1|root,COG1975@2|Bacteria,2I8ZS@201174|Actinobacteria,4E9UH@85010|Pseudonocardiales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
MMS1_k127_2332565_2	1121877.JQKF01000039_gene1847	1.468e-79	275.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS1_k127_2332565_1	479435.Kfla_5154	1.24e-88	302.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4DPD1@85009|Propionibacteriales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS1_k127_2332565_3	298654.FraEuI1c_4032	3.118e-60	229.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4EVAJ@85013|Frankiales	201174|Actinobacteria	M	Exporter of polyketide	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
MMS1_k127_2332565_4	1340434.AXVA01000008_gene3530	2.368e-42	158.0	COG1028@1|root,COG1028@2|Bacteria,1TT3M@1239|Firmicutes,4HTB6@91061|Bacilli,1ZMBY@1386|Bacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS1_k127_2344474_1	316274.Haur_3529	1.024e-136	456.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2G64D@200795|Chloroflexi,374WF@32061|Chloroflexia	32061|Chloroflexia	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
MMS1_k127_2344474_4	555079.Toce_2252	3.131e-33	133.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,42GRT@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
MMS1_k127_2344474_5	561175.KB894093_gene3817	4.317e-26	111.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4EJZ9@85012|Streptosporangiales	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
MMS1_k127_2344474_3	1121877.JQKF01000007_gene976	2.548e-50	182.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CN4R@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
MMS1_k127_2344474_6	1229780.BN381_100143	2.407e-25	110.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,3UWQU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
MMS1_k127_2344474_2	525909.Afer_0040	3.372e-100	333.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4CNSX@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
MMS1_k127_2344474_7	43354.JOIJ01000001_gene414	4.159e-23	104.0	2CQNK@1|root,32SMG@2|Bacteria,2IIJ7@201174|Actinobacteria,4E3ED@85010|Pseudonocardiales	201174|Actinobacteria	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
MMS1_k127_2344474_8	521096.Tpau_4194	5.082e-12	74.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
MMS1_k127_2344474_0	1121877.JQKF01000017_gene209	1.716e-190	602.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CNE8@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
MMS1_k127_2352580_0	1121877.JQKF01000008_gene608	4.631e-224	706.0	COG0247@1|root,COG0247@2|Bacteria,2H3F2@201174|Actinobacteria,4CNI3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
MMS1_k127_2352580_2	1121877.JQKF01000008_gene607	3.672e-101	338.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CNP3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
MMS1_k127_2352580_3	525909.Afer_0969	7.479e-87	294.0	COG2086@1|root,COG2086@2|Bacteria,2H4H4@201174|Actinobacteria,4CNJD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
MMS1_k127_2352580_1	525909.Afer_1052	4.078e-166	529.0	COG2516@1|root,COG2516@2|Bacteria,2H2JZ@201174|Actinobacteria	201174|Actinobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
MMS1_k127_2352580_4	882083.SacmaDRAFT_1929	2.254e-13	75.0	COG0095@1|root,COG0095@2|Bacteria,2HW3P@201174|Actinobacteria,4ECVC@85010|Pseudonocardiales	201174|Actinobacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
MMS1_k127_2358390_0	1121877.JQKF01000024_gene2381	0.0	1075.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CMWS@84992|Acidimicrobiia	84992|Acidimicrobiia	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
MMS1_k127_2366080_1	525909.Afer_0391	0.0	1555.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CMVP@84992|Acidimicrobiia	84992|Acidimicrobiia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
MMS1_k127_2366080_0	525909.Afer_0392	0.0	1918.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CMT4@84992|Acidimicrobiia	84992|Acidimicrobiia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMS1_k127_2366080_4	525909.Afer_0393	6.214e-66	226.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4CN6J@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
MMS1_k127_2366080_3	1229780.BN381_180002	5.992e-71	243.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,3UWK1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
MMS1_k127_2366080_2	1121877.JQKF01000009_gene551	0.0	1119.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CMTM@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS1_k127_2366080_5	1121877.JQKF01000009_gene550	1.156e-39	149.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CMSE@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMS1_k127_236676_1	631362.Thi970DRAFT_03960	8.146e-53	203.0	COG2206@1|root,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,1S4K4@1236|Gammaproteobacteria,1X2BG@135613|Chromatiales	135613|Chromatiales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,PAS_4
MMS1_k127_236676_0	420324.KI912037_gene2397	1.504e-71	260.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,1QWKB@1224|Proteobacteria,2TX0H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE,Guanylate_cyc,Hydrolase_4
MMS1_k127_236676_5	33898.JRHJ01000011_gene4922	8.88e-11	74.0	COG2909@1|root,COG2909@2|Bacteria,2GM1B@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
MMS1_k127_236676_2	1158050.KB895456_gene2018	2.28e-50	186.0	COG2808@1|root,COG2808@2|Bacteria,2IEXV@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
MMS1_k127_236676_3	1157640.AQWO01000028_gene6615	5.325e-26	111.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
MMS1_k127_2373901_14	1184607.AUCHE_26_00220	7.601e-27	117.0	COG2198@1|root,COG2198@2|Bacteria,2I45J@201174|Actinobacteria,4F7T4@85018|Dermatophilaceae	201174|Actinobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
MMS1_k127_2373901_9	525909.Afer_1069	9.015e-50	185.0	2EFBW@1|root,3394U@2|Bacteria,2H758@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2373901_11	1380390.JIAT01000010_gene4351	1.837e-38	157.0	COG3511@1|root,COG3511@2|Bacteria,2II4P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
MMS1_k127_2373901_10	1121877.JQKF01000013_gene260	1.323e-43	172.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	scrK	-	2.7.1.2,2.7.1.4	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMS1_k127_2373901_2	469383.Cwoe_2511	5.383e-149	479.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4CPEH@84995|Rubrobacteria	84995|Rubrobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
MMS1_k127_2373901_1	1123024.AUII01000031_gene517	2.976e-155	496.0	COG1237@1|root,COG1237@2|Bacteria,2I8H7@201174|Actinobacteria,4DZYW@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
MMS1_k127_2373901_3	164757.Mjls_3416	3.797e-126	412.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,237XV@1762|Mycobacteriaceae	201174|Actinobacteria	S	alcohol dehydrogenase	sadh	-	1.1.1.1	ko:K13953,ko:K18382	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS1_k127_2373901_0	1123320.KB889675_gene4050	6.824e-163	528.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS1_k127_2373901_5	404589.Anae109_0474	2.993e-68	240.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,43A9Z@68525|delta/epsilon subdivisions,2X37W@28221|Deltaproteobacteria,2YV2G@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
MMS1_k127_2373901_6	543632.JOJL01000034_gene5129	2.713e-59	217.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4DINJ@85008|Micromonosporales	201174|Actinobacteria	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
MMS1_k127_2373901_12	1306174.JODP01000006_gene2899	5.943e-36	151.0	COG2310@1|root,COG2310@2|Bacteria,2IE9A@201174|Actinobacteria	201174|Actinobacteria	T	stress, protein	-	-	-	-	-	-	-	-	-	-	-	-	TerD
MMS1_k127_2373901_7	1136417.AZWE01000058_gene293	2.945e-54	193.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4DDTU@85008|Micromonosporales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS1_k127_2373901_8	1120950.KB892746_gene3541	8.691e-53	189.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4DS49@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
MMS1_k127_2373901_13	1120950.KB892746_gene3542	1.205e-27	118.0	COG1846@1|root,COG1846@2|Bacteria,2II5E@201174|Actinobacteria,4DVTU@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMS1_k127_2373901_4	675635.Psed_0584	1.981e-95	321.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJD@85010|Pseudonocardiales	201174|Actinobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990,ko:K18232	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC_tran,DUF4162
MMS1_k127_2375272_6	981369.JQMJ01000001_gene6910	4.139e-30	127.0	COG1409@1|root,COG1409@2|Bacteria,2GK31@201174|Actinobacteria	201174|Actinobacteria	M	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
MMS1_k127_2375272_3	1121877.JQKF01000008_gene642	7.977e-70	252.0	COG0477@1|root,COG2814@2|Bacteria,2IFXN@201174|Actinobacteria,4CN8C@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2375272_1	525909.Afer_0507	6.837e-106	351.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4CN5E@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMS1_k127_2375272_0	525909.Afer_0506	3.496e-128	418.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4CN85@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMS1_k127_2375272_2	525909.Afer_0505	3.355e-92	309.0	COG0411@1|root,COG0411@2|Bacteria,2I3Z1@201174|Actinobacteria,4CP54@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
MMS1_k127_2375272_4	388401.RB2150_11686	1.168e-55	205.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria,3ZGQ2@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	E	amino acid	livF2	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
MMS1_k127_2375272_5	525909.Afer_0503	1.492e-44	166.0	COG0683@1|root,COG0683@2|Bacteria,2HGK2@201174|Actinobacteria,4CNIP@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS1_k127_2379027_0	1313172.YM304_02490	8.874e-78	275.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CN0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
MMS1_k127_2379027_3	298654.FraEuI1c_0111	1.813e-52	194.0	COG1691@1|root,COG1691@2|Bacteria,2IAKU@201174|Actinobacteria,4EU7Y@85013|Frankiales	201174|Actinobacteria	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
MMS1_k127_2379027_1	1463856.JOHY01000088_gene2417	2.696e-74	264.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
MMS1_k127_2379027_2	1121877.JQKF01000011_gene373	6.991e-55	196.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS1_k127_2389245_0	1121877.JQKF01000001_gene1333	3.028e-214	679.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4CMQ1@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
MMS1_k127_2389245_3	1122182.KB903814_gene3192	5.29e-59	213.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria,4DBSC@85008|Micromonosporales	201174|Actinobacteria	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
MMS1_k127_2389245_4	316278.SynRCC307_1737	8.555e-52	194.0	COG0352@1|root,COG0352@2|Bacteria,1G1VB@1117|Cyanobacteria,1GYVT@1129|Synechococcus	1117|Cyanobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.thiE	TMP-TENI
MMS1_k127_2389245_8	1313172.YM304_30260	3.365e-20	100.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
MMS1_k127_2389245_5	525909.Afer_0707	5.087e-36	140.0	COG0599@1|root,COG0599@2|Bacteria,2IRPW@201174|Actinobacteria,4CNXZ@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS1_k127_2389245_1	1229780.BN381_210093	1.475e-134	454.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,3UXCB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_2389245_2	1229780.BN381_210088	2.88e-84	284.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,3UXGK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS1_k127_2389245_7	402881.Plav_2674	2.51e-32	134.0	COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,2U5MZ@28211|Alphaproteobacteria,1JP43@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS1_k127_2389245_6	469383.Cwoe_5398	1.368e-32	129.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CPSF@84995|Rubrobacteria	84995|Rubrobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMS1_k127_240246_9	1214101.BN159_2369	1.604e-28	125.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria	201174|Actinobacteria	H	Pyrimidine reductase, riboflavin biosynthesis	-	-	1.1.1.193	ko:K00082	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R03458	RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
MMS1_k127_240246_2	479431.Namu_2606	1.487e-87	300.0	COG1881@1|root,COG1881@2|Bacteria,2IRRV@201174|Actinobacteria	201174|Actinobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
MMS1_k127_240246_0	1445613.JALM01000064_gene1368	3.344e-89	306.0	COG1485@1|root,COG1485@2|Bacteria,2GNQA@201174|Actinobacteria,4DZR8@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM AFG1-like ATPase	-	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
MMS1_k127_240246_1	351607.Acel_0516	6.707e-89	306.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4EXC4@85013|Frankiales	201174|Actinobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
MMS1_k127_240246_3	525909.Afer_0752	1.543e-87	301.0	COG1085@1|root,COG1085@2|Bacteria,2HGHY@201174|Actinobacteria,4CNFK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	galactose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_240246_11	1304865.JAGF01000001_gene1532	5.587e-21	103.0	COG4097@1|root,COG4097@2|Bacteria	2|Bacteria	P	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Ferric_reduct,NAD_binding_1
MMS1_k127_240246_8	1304865.JAGF01000001_gene1531	7.197e-33	141.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMS1_k127_240246_5	1278078.G419_07199	3.194e-63	226.0	COG4221@1|root,COG4221@2|Bacteria,2I2DY@201174|Actinobacteria,4FV05@85025|Nocardiaceae	201174|Actinobacteria	S	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS1_k127_240246_6	1121877.JQKF01000001_gene1372	8.11e-58	207.0	COG1651@1|root,COG1651@2|Bacteria,2IT6U@201174|Actinobacteria,4CNRR@84992|Acidimicrobiia	84992|Acidimicrobiia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
MMS1_k127_240246_10	369723.Strop_1261	7.537e-26	115.0	COG0406@1|root,COG0494@1|root,COG0406@2|Bacteria,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4DB83@85008|Micromonosporales	201174|Actinobacteria	GL	Nudix hydrolase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
MMS1_k127_240246_7	1121877.JQKF01000001_gene1373	2.232e-33	135.0	COG0671@1|root,COG0671@2|Bacteria,2HGAE@201174|Actinobacteria,4CN9F@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
MMS1_k127_240246_4	1229780.BN381_80226	7.934e-70	246.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,3UWVT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
MMS1_k127_2415832_5	1313172.YM304_19200	1.896e-22	98.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	sdaAB	-	2.7.6.5,3.1.7.2,4.3.1.17,4.3.1.19	ko:K01139,ko:K01752,ko:K01754	ko00230,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00336,R00429,R00590,R00996	RC00002,RC00078,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	ACT,HD_4,PALP,RelA_SpoT,SDH_beta
MMS1_k127_2415832_0	1713.JOFV01000001_gene2097	2.78e-183	580.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	-	-	2.6.1.1,2.6.1.83	ko:K00812,ko:K08969,ko:K10206,ko:K14261	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00034,M00527	R00355,R00694,R00734,R00896,R02433,R02619,R05052,R07396,R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS1_k127_2415832_4	1313172.YM304_19170	1.027e-41	167.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CNH1@84992|Acidimicrobiia	201174|Actinobacteria	G	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMS1_k127_2415832_3	525909.Afer_0938	7.967e-43	162.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria,4CN9D@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
MMS1_k127_2415832_1	1313172.YM304_19140	3.318e-84	293.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4CN28@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_2415832_2	1229780.BN381_140043	2.438e-59	216.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
MMS1_k127_242365_0	1121877.JQKF01000011_gene411	9.049e-252	793.0	COG1298@1|root,COG1298@2|Bacteria,2IB5S@201174|Actinobacteria,4CNFA@84992|Acidimicrobiia	84992|Acidimicrobiia	N	FHIPEP family	-	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
MMS1_k127_242365_1	525909.Afer_0208	3.947e-86	302.0	COG1256@1|root,COG1256@2|Bacteria,2GNXQ@201174|Actinobacteria,4CNM2@84992|Acidimicrobiia	84992|Acidimicrobiia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
MMS1_k127_242365_3	525909.Afer_0209	7.183e-49	197.0	COG1344@1|root,COG1344@2|Bacteria,2IA40@201174|Actinobacteria,4CNMZ@84992|Acidimicrobiia	84992|Acidimicrobiia	N	Bacterial flagellin N-terminal helical region	-	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_N
MMS1_k127_242365_4	1121877.JQKF01000025_gene841	3.967e-26	113.0	COG1699@1|root,COG1699@2|Bacteria,2HGUT@201174|Actinobacteria,4CNVC@84992|Acidimicrobiia	84992|Acidimicrobiia	N	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
MMS1_k127_242365_5	1121877.JQKF01000025_gene842	6.419e-15	78.0	COG1551@1|root,COG1551@2|Bacteria,2GRPH@201174|Actinobacteria,4CNZ8@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
MMS1_k127_242365_2	398767.Glov_1832	2.781e-79	279.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2WIX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
MMS1_k127_242365_6	525909.Afer_0150	9.47e-13	76.0	COG1868@1|root,COG1868@2|Bacteria,2ICP2@201174|Actinobacteria,4CNKM@84992|Acidimicrobiia	84992|Acidimicrobiia	N	Flagellar motor switch protein FliM	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
MMS1_k127_2434762_3	235985.BBPN01000009_gene3788	4.103e-31	126.0	COG0477@1|root,COG0477@2|Bacteria,2GK8M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2434762_0	471852.Tcur_0107	3.961e-176	567.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
MMS1_k127_2434762_1	1123023.JIAI01000001_gene6257	3.976e-146	478.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4E1ZB@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS1_k127_2434762_2	1121877.JQKF01000020_gene2504	1.741e-57	204.0	COG0641@1|root,COG0641@2|Bacteria,2GMTV@201174|Actinobacteria	201174|Actinobacteria	V	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Radical_SAM,SEC-C,SPASM
MMS1_k127_2437630_4	525909.Afer_1080	1.845e-19	90.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CMR0@84992|Acidimicrobiia	84992|Acidimicrobiia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
MMS1_k127_2437630_1	1229780.BN381_80408	1.624e-191	606.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,3UW6D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Ribosomal protein S1-like RNA-binding domain	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
MMS1_k127_2437630_3	1463921.JODF01000012_gene332	5.404e-34	147.0	COG1432@1|root,COG1432@2|Bacteria,2GKS5@201174|Actinobacteria	201174|Actinobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
MMS1_k127_2437630_2	1944.JOAZ01000005_gene1928	1.236e-49	183.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,418Q3@629295|Streptomyces griseus group	201174|Actinobacteria	H	Dephospho-CoA kinase	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
MMS1_k127_2437630_0	1121877.JQKF01000021_gene2185	3.521e-262	816.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CMWE@84992|Acidimicrobiia	84992|Acidimicrobiia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
MMS1_k127_2464810_3	1121877.JQKF01000003_gene1461	1.935e-49	177.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CMWQ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS1_k127_2464810_0	525909.Afer_1548	1.801e-254	796.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CMQ6@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
MMS1_k127_2464810_2	1313172.YM304_33800	1.281e-144	473.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CMV1@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
MMS1_k127_2464810_1	1313172.YM304_33810	2.457e-176	567.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CMQJ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS1_k127_2464810_4	1122919.KB905603_gene4704	5.915e-15	77.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,26ZAP@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
MMS1_k127_246635_2	398767.Glov_0244	3.969e-60	212.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
MMS1_k127_246635_3	2074.JNYD01000014_gene7037	3.427e-53	192.0	COG0678@1|root,COG0678@2|Bacteria,2IP2N@201174|Actinobacteria	201174|Actinobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
MMS1_k127_246635_1	525909.Afer_1003	4.287e-147	481.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CMWK@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
MMS1_k127_246635_0	711393.AYRX01000017_gene2775	2.334e-202	649.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
MMS1_k127_2469947_4	743718.Isova_2723	3.367e-80	271.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4F382@85017|Promicromonosporaceae	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
MMS1_k127_2469947_3	525909.Afer_1991	4.236e-98	330.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4CNHS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS1_k127_2469947_1	525909.Afer_1572	1.58e-123	402.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CMZ4@84992|Acidimicrobiia	84992|Acidimicrobiia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMS1_k127_2469947_5	593117.TGAM_1902	8.576e-05	51.0	COG1030@1|root,arCOG01910@2157|Archaea,2XW1R@28890|Euryarchaeota,242U5@183968|Thermococci	183968|Thermococci	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
MMS1_k127_2469947_2	1121877.JQKF01000020_gene2482	2.268e-102	344.0	29BBV@1|root,2ZCHD@2|Bacteria,2I82W@201174|Actinobacteria,4CNI8@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2469947_0	1313172.YM304_13880	6.594e-148	486.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CNIJ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
MMS1_k127_2471993_2	525909.Afer_1749	2.287e-59	208.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4CN0W@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS1_k127_2471993_1	1894.JOER01000028_gene5863	9.446e-63	224.0	COG0511@1|root,COG0511@2|Bacteria,2GMCA@201174|Actinobacteria	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
MMS1_k127_2471993_0	1313172.YM304_27740	1.275e-129	420.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CMZT@84992|Acidimicrobiia	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
MMS1_k127_2471993_5	1122182.KB903813_gene2757	1.099e-25	108.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4DE3Z@85008|Micromonosporales	201174|Actinobacteria	H	ThiS family	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS1_k127_2471993_4	525909.Afer_1753	2.129e-34	137.0	COG1310@1|root,COG1310@2|Bacteria,2HG96@201174|Actinobacteria,4CN7H@84992|Acidimicrobiia	84992|Acidimicrobiia	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
MMS1_k127_2471993_3	1121877.JQKF01000008_gene674	1.169e-44	167.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CN4T@84992|Acidimicrobiia	84992|Acidimicrobiia	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
MMS1_k127_2471993_6	1151122.AQYD01000007_gene740	0.0008914	51.0	2ENWQ@1|root,33GHN@2|Bacteria,2GX0I@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4232
MMS1_k127_247344_0	530564.Psta_3074	1.332e-192	619.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,2IWWG@203682|Planctomycetes	203682|Planctomycetes	T	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K02487,ko:K03407,ko:K06596	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
MMS1_k127_247344_5	1123242.JH636434_gene4224	2.708e-45	168.0	COG0835@1|root,COG0835@2|Bacteria,2IZN1@203682|Planctomycetes	203682|Planctomycetes	NT	CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
MMS1_k127_247344_4	525909.Afer_0753	7.644e-78	282.0	COG0840@1|root,COG0840@2|Bacteria,2GP45@201174|Actinobacteria	201174|Actinobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
MMS1_k127_247344_1	28042.GU90_07435	1.318e-114	379.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4DX45@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS1_k127_247344_7	1869.MB27_39495	1.363e-19	94.0	2E77D@1|root,331R6@2|Bacteria,2I2XP@201174|Actinobacteria,4DF3H@85008|Micromonosporales	201174|Actinobacteria	S	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
MMS1_k127_247344_6	2045.KR76_05375	1.462e-30	130.0	COG0745@1|root,COG0745@2|Bacteria,2I3KP@201174|Actinobacteria,4DUEM@85009|Propionibacteriales	201174|Actinobacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
MMS1_k127_247344_3	1048339.KB913029_gene889	6.047e-78	270.0	COG1352@1|root,COG1352@2|Bacteria,2HHZ1@201174|Actinobacteria,4ESM3@85013|Frankiales	201174|Actinobacteria	NT	PFAM MCP methyltransferase CheR-type	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
MMS1_k127_247344_2	526225.Gobs_5003	5.896e-96	329.0	COG2201@1|root,COG2201@2|Bacteria,2GMBC@201174|Actinobacteria,4ES6U@85013|Frankiales	201174|Actinobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
MMS1_k127_2487222_4	1313172.YM304_38910	5.841e-22	100.0	2A58G@1|root,30TXM@2|Bacteria,2HG9Z@201174|Actinobacteria,4CN8R@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2487222_2	666686.B1NLA3E_01565	1.499e-72	252.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,1ZB9C@1386|Bacillus	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
MMS1_k127_2487222_5	555079.Toce_1504	1.424e-11	68.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,24R3W@186801|Clostridia,42H8G@68295|Thermoanaerobacterales	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
MMS1_k127_2487222_1	1229780.BN381_130013	5.181e-82	282.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,3UWES@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
MMS1_k127_2487222_0	1313172.YM304_38920	9.18e-139	458.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4CMWU@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
MMS1_k127_2487222_3	1121877.JQKF01000006_gene933	2.072e-70	247.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CMZB@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
MMS1_k127_2489364_1	134676.ACPL_418	4.848e-105	355.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4D8GJ@85008|Micromonosporales	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
MMS1_k127_2489364_3	1121877.JQKF01000010_gene702	2.533e-54	206.0	2CC95@1|root,31D2W@2|Bacteria,2HGQY@201174|Actinobacteria,4CNT8@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2489364_0	1121877.JQKF01000045_gene1211	5.742e-177	568.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CMU6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS1_k127_2489364_2	1304275.C41B8_06792	8.958e-69	242.0	COG1028@1|root,COG1028@2|Bacteria,1RBU3@1224|Proteobacteria,1S5MG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	short-chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS1_k127_2489364_6	526225.Gobs_4186	3.293e-25	117.0	COG3153@1|root,COG3153@2|Bacteria,2I3D1@201174|Actinobacteria,4EXH9@85013|Frankiales	201174|Actinobacteria	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS1_k127_2489364_4	1332071.L581_3758	5.013e-50	184.0	COG1670@1|root,COG1670@2|Bacteria,1RDXV@1224|Proteobacteria,1SCX8@1236|Gammaproteobacteria,400K6@613|Serratia	1236|Gammaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS1_k127_2489364_5	1120948.KB903218_gene1996	1.493e-40	154.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E27I@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_2505684_0	263358.VAB18032_27931	3.045e-102	347.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DCDB@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
MMS1_k127_2505684_1	1089549.AZUQ01000001_gene356	3.675e-102	345.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	tnpA	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
MMS1_k127_2513524_4	1121877.JQKF01000023_gene2230	6.345e-71	251.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,4CMUN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
MMS1_k127_2513524_2	1121877.JQKF01000023_gene2231	1.546e-122	406.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CMPG@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
MMS1_k127_2513524_8	1283283.ATXA01000053_gene4187	2.058e-51	191.0	COG2227@1|root,COG2227@2|Bacteria,2GU8A@201174|Actinobacteria	201174|Actinobacteria	H	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2513524_13	1157490.EL26_22515	2.662e-43	169.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,278S4@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
MMS1_k127_2513524_12	196164.23493351	1.509e-44	164.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,22MY1@1653|Corynebacteriaceae	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
MMS1_k127_2513524_16	525245.HMPREF0044_0519	8.214e-13	71.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,4D6F8@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
MMS1_k127_2513524_5	525909.Afer_1678	4.241e-69	240.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CMZR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
MMS1_k127_2513524_17	525909.Afer_1680	3.198e-07	57.0	2BAT3@1|root,3248B@2|Bacteria,2HH2N@201174|Actinobacteria,4CP2P@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2513524_1	1121877.JQKF01000023_gene2237	9.632e-123	400.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CMTS@84992|Acidimicrobiia	84992|Acidimicrobiia	F	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
MMS1_k127_2513524_10	1313172.YM304_20590	2.605e-48	177.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4CN1Q@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMS1_k127_2513524_3	1229780.BN381_50158	2.736e-94	322.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,3UWIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
MMS1_k127_2513524_11	515620.EUBELI_20111	7.03e-46	170.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,25W25@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
MMS1_k127_2513524_0	1121877.JQKF01000023_gene2239	1.642e-176	561.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4CN1A@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
MMS1_k127_2513524_9	358823.DF19_05430	4.067e-49	182.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
MMS1_k127_2513524_6	1229780.BN381_50155	3.08e-63	230.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,3UWIG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
MMS1_k127_2513524_7	1229780.BN381_50154	2.761e-53	192.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,3UWS7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
MMS1_k127_2513524_15	1078020.KEK_01665	1.78e-14	80.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria,233QA@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2514886_3	1313172.YM304_18530	8.351e-40	155.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CMPC@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
MMS1_k127_2514886_0	1121877.JQKF01000004_gene1079	1.372e-103	357.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CMTA@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
MMS1_k127_2514886_4	656024.FsymDg_3695	1.341e-21	97.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4ETC7@85013|Frankiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
MMS1_k127_2514886_1	882082.SaccyDRAFT_2954	1.354e-89	306.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,4DZFZ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
MMS1_k127_2514886_2	1246995.AFR_27275	9.319e-48	177.0	COG1670@1|root,COG1670@2|Bacteria,2IFNY@201174|Actinobacteria,4DEEQ@85008|Micromonosporales	201174|Actinobacteria	J	Gcn5-related n-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS1_k127_2514886_5	436229.JOEH01000011_gene5513	1.204e-07	63.0	2EUNJ@1|root,33N4E@2|Bacteria,2GZIG@201174|Actinobacteria,2NIXF@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function (DUF4232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4232
MMS1_k127_2520607_3	1121946.AUAX01000008_gene7362	8.316e-131	430.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4D9VG@85008|Micromonosporales	201174|Actinobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
MMS1_k127_2520607_0	1121934.AUDX01000004_gene2663	1.212e-155	514.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FK8K@85023|Microbacteriaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2520607_7	1306406.ASHX01000001_gene3927	5.08e-41	163.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter DMT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS1_k127_2520607_4	196162.Noca_2053	1.733e-59	208.0	COG2514@1|root,COG2514@2|Bacteria,2I4TW@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS1_k127_2520607_6	479433.Caci_1911	9.474e-44	164.0	COG4420@1|root,COG4420@2|Bacteria,2IHZA@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2520607_1	525909.Afer_0308	2.84e-155	504.0	COG1914@1|root,COG1914@2|Bacteria,2HGJ6@201174|Actinobacteria	201174|Actinobacteria	P	Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
MMS1_k127_2520607_2	1229780.BN381_350032	1.57e-137	450.0	COG1106@1|root,COG1106@2|Bacteria,2GMVX@201174|Actinobacteria	201174|Actinobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
MMS1_k127_2520607_5	1229780.BN381_350031	6.277e-47	178.0	2DNYB@1|root,32ZS8@2|Bacteria	2|Bacteria	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
MMS1_k127_2520607_8	929712.KI912613_gene1793	4.824e-08	56.0	COG0388@1|root,COG0388@2|Bacteria,2IFF1@201174|Actinobacteria	201174|Actinobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
MMS1_k127_2523040_3	225117.XP_009372155.1	4.001e-53	193.0	COG0152@1|root,KOG2835@2759|Eukaryota,37SAJ@33090|Viridiplantae,3GC4Z@35493|Streptophyta,4JIPK@91835|fabids	35493|Streptophyta	F	Phosphoribosylaminoimidazole carboxylase	-	-	4.1.1.21	ko:K11808	ko00230,ko01100,ko01110,map00230,map01100,map01110	M00048	R04209	RC00590	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,ATP-grasp
MMS1_k127_2523040_1	1128421.JAGA01000001_gene2276	1.147e-79	280.0	COG0026@1|root,COG0026@2|Bacteria	2|Bacteria	F	5-(carboxyamino)imidazole ribonucleotide synthase activity	purK	GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477	ATP-grasp
MMS1_k127_2523040_2	1313172.YM304_19020	7.099e-77	276.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4CMTY@84992|Acidimicrobiia	201174|Actinobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
MMS1_k127_2523040_0	1229780.BN381_170034	1.626e-94	330.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,3UWFB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
MMS1_k127_2524369_2	1313172.YM304_02170	9.126e-42	161.0	COG1716@1|root,COG1716@2|Bacteria,2HG8X@201174|Actinobacteria,4CN6T@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
MMS1_k127_2524369_3	1968.JOEV01000002_gene7297	4.01e-37	148.0	COG2128@1|root,COG2128@2|Bacteria,2IKUZ@201174|Actinobacteria	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMS1_k127_2524369_1	543632.JOJL01000035_gene5071	4.344e-86	291.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2524369_0	1435356.Y013_05145	3.975e-87	303.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4FWK9@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
MMS1_k127_2527259_1	1229780.BN381_150139	7.815e-262	826.0	COG0550@1|root,COG0550@2|Bacteria,2GJU7@201174|Actinobacteria,3UW7H@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
MMS1_k127_2527259_2	525909.Afer_1922	5.826e-226	725.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4CNMX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS1_k127_2527259_4	1463934.JOCF01000065_gene4286	1.171e-65	231.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria	201174|Actinobacteria	P	PFAM TrkA-N domain protein	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
MMS1_k127_2527259_3	525909.Afer_1924	3.5e-76	262.0	COG0569@1|root,COG0569@2|Bacteria,2HH1S@201174|Actinobacteria,4CP21@84992|Acidimicrobiia	84992|Acidimicrobiia	C	TrkA-C domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
MMS1_k127_2527259_5	1304275.C41B8_18191	4.721e-06	57.0	COG3381@1|root,COG3381@2|Bacteria	2|Bacteria	S	protein complex oligomerization	dmsD	GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
MMS1_k127_2527259_0	525909.Afer_1020	0.0	1422.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMS1_k127_2532564_1	525909.Afer_0948	9.367e-204	648.0	COG1113@1|root,COG1113@2|Bacteria,2I5YG@201174|Actinobacteria	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS1_k127_2532564_0	1121877.JQKF01000004_gene1119	4.584e-245	768.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CMSF@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,S1
MMS1_k127_2536936_0	1121877.JQKF01000037_gene1793	6.29e-49	184.0	COG0483@1|root,COG0483@2|Bacteria,2HGA4@201174|Actinobacteria,4CN94@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
MMS1_k127_2536936_1	1157634.KB913010_gene778	8.363e-40	158.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria	201174|Actinobacteria	Q	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
MMS1_k127_2536936_3	525909.Afer_0613	7.852e-11	70.0	2ANHR@1|root,31DGH@2|Bacteria,2HH3Q@201174|Actinobacteria,4CP3V@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2536936_2	1380391.JIAS01000018_gene945	1.059e-35	147.0	COG0561@1|root,COG0561@2|Bacteria,1MXIH@1224|Proteobacteria,2TTNZ@28211|Alphaproteobacteria,2JV1M@204441|Rhodospirillales	204441|Rhodospirillales	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
MMS1_k127_2536936_4	1380354.JIAN01000007_gene285	1.436e-08	58.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4F0J8@85016|Cellulomonadaceae	201174|Actinobacteria	M	PFAM MscS Mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
MMS1_k127_2543552_0	292.DM42_910	1.236e-96	331.0	28MGB@1|root,2ZATK@2|Bacteria,1R4PG@1224|Proteobacteria,2VZY0@28216|Betaproteobacteria,1KDDF@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2555083_0	469371.Tbis_3171	7.829e-131	428.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4E07J@85010|Pseudonocardiales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
MMS1_k127_2555083_1	582515.KR51_00012140	6.817e-50	188.0	COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
MMS1_k127_2558033_10	637390.AFOH01000047_gene2003	6.874e-40	153.0	COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,1RP6K@1236|Gammaproteobacteria,2NCK9@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.11	ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
MMS1_k127_2558033_12	235985.BBPN01000009_gene3761	7.952e-09	59.0	COG1290@1|root,COG1290@2|Bacteria,2GTS3@201174|Actinobacteria,2NK48@228398|Streptacidiphilus	201174|Actinobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2558033_1	525909.Afer_1523	2.008e-201	643.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria,4CNNI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2558033_11	446468.Ndas_2259	1.691e-12	73.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4EJS7@85012|Streptosporangiales	201174|Actinobacteria	K	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
MMS1_k127_2558033_9	1121877.JQKF01000010_gene689	6.809e-46	174.0	COG0704@1|root,COG0704@2|Bacteria,2HGEH@201174|Actinobacteria,4CNCK@84992|Acidimicrobiia	84992|Acidimicrobiia	P	PhoU domain	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
MMS1_k127_2558033_2	525909.Afer_1444	2.364e-138	446.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4CMRY@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS1_k127_2558033_5	525909.Afer_1443	3.344e-75	263.0	COG0583@1|root,COG0583@2|Bacteria,2HF8Y@201174|Actinobacteria,4CN2C@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
MMS1_k127_2558033_3	1206735.BAGG01000003_gene248	1.2e-91	316.0	COG0769@1|root,COG0769@2|Bacteria,2I2TV@201174|Actinobacteria,4FUN3@85025|Nocardiaceae	201174|Actinobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
MMS1_k127_2558033_8	679197.HMPREF9336_04092	1.32e-53	198.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria	201174|Actinobacteria	S	glutamine amidotransferase	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
MMS1_k127_2558033_7	525909.Afer_1409	1.732e-68	241.0	COG2188@1|root,COG2188@2|Bacteria,2HF8W@201174|Actinobacteria,4CN6C@84992|Acidimicrobiia	84992|Acidimicrobiia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
MMS1_k127_2558033_6	525909.Afer_1429	1.556e-68	244.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria,4CN1J@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
MMS1_k127_2558033_0	1121877.JQKF01000015_gene84	5.779e-271	841.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria,4CMV3@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
MMS1_k127_2558033_4	525909.Afer_1431	9.785e-89	307.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,4CMYA@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS1_k127_2565113_0	1408418.JNJH01000061_gene1195	1.756e-74	267.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2TUFG@28211|Alphaproteobacteria,2JQVA@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_2565113_2	103690.17134333	3.109e-55	208.0	COG0438@1|root,COG0438@2|Bacteria,1G271@1117|Cyanobacteria,1HPCT@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	icsA	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMS1_k127_2565113_1	743299.Acife_1002	2.339e-66	245.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,2NC3G@225057|Acidithiobacillales	225057|Acidithiobacillales	P	ABC transporter, transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
MMS1_k127_2587731_6	118166.JH976537_gene1696	1.494e-12	70.0	COG0169@1|root,COG0169@2|Bacteria,1G0CS@1117|Cyanobacteria,1H8SN@1150|Oscillatoriales	1117|Cyanobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
MMS1_k127_2587731_4	525909.Afer_0953	4.04e-63	231.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CN7T@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
MMS1_k127_2587731_5	234267.Acid_7012	2.21e-19	93.0	COG0816@1|root,COG0816@2|Bacteria,3Y59A@57723|Acidobacteria	57723|Acidobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
MMS1_k127_2587731_0	1121877.JQKF01000002_gene1677	4.011e-298	937.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CMTK@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
MMS1_k127_2587731_1	1121877.JQKF01000045_gene1208	2.145e-233	735.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CMU8@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
MMS1_k127_2587731_3	525909.Afer_0533	3.976e-71	254.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CMYY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
MMS1_k127_2587731_2	1454010.JEOE01000001_gene572	2.315e-101	338.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4F0M3@85016|Cellulomonadaceae	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
MMS1_k127_2592805_2	311424.DhcVS_255	3.814e-50	182.0	COG3727@1|root,COG3727@2|Bacteria,2G92F@200795|Chloroflexi	200795|Chloroflexi	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	-	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
MMS1_k127_2592805_0	1051632.TPY_0067	0.0	1059.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WCQQ@538999|Clostridiales incertae sedis	186801|Clostridia	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C,UvrD_C_2
MMS1_k127_2592805_1	1051632.TPY_0066	4.223e-121	403.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,2490C@186801|Clostridia	186801|Clostridia	H	PFAM C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
MMS1_k127_2631846_1	525909.Afer_0503	2.235e-102	340.0	COG0683@1|root,COG0683@2|Bacteria,2HGK2@201174|Actinobacteria,4CNIP@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS1_k127_2631846_2	211165.AJLN01000137_gene1503	1.291e-32	141.0	COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,1JI27@1189|Stigonemataceae	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2631846_0	765420.OSCT_1907	5.737e-249	780.0	COG0365@1|root,COG0365@2|Bacteria,2G653@200795|Chloroflexi	200795|Chloroflexi	I	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_2634299_1	1121877.JQKF01000002_gene1692	1.309e-29	124.0	COG2246@1|root,COG2246@2|Bacteria,2HGV5@201174|Actinobacteria,4CNVR@84992|Acidimicrobiia	84992|Acidimicrobiia	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2634299_0	1122138.AQUZ01000007_gene3234	9.602e-71	249.0	COG0451@1|root,COG0451@2|Bacteria,2IAAT@201174|Actinobacteria	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS1_k127_2644302_2	317936.Nos7107_5285	1.237e-99	333.0	COG0667@1|root,COG0667@2|Bacteria,1G3WV@1117|Cyanobacteria,1HMPK@1161|Nostocales	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
MMS1_k127_2644302_0	1121877.JQKF01000002_gene1720	1.479e-206	653.0	COG1003@1|root,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4CMXT@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Glycine cleavage system P-protein	-	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
MMS1_k127_2644302_1	1121877.JQKF01000002_gene1721	1.573e-143	469.0	COG0403@1|root,COG0403@2|Bacteria,2IBH2@201174|Actinobacteria,4CNJP@84992|Acidimicrobiia	84992|Acidimicrobiia	C	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
MMS1_k127_2644302_3	1313172.YM304_25740	5.635e-11	65.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CMQS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Glycine cleavage T-protein C-terminal barrel domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
MMS1_k127_2663534_5	525909.Afer_0850	6.343e-15	76.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CMV0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
MMS1_k127_2663534_0	1121877.JQKF01000028_gene2134	1.13e-147	474.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CMQP@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
MMS1_k127_2663534_4	645127.ckrop_0971	7.242e-50	190.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,22JIQ@1653|Corynebacteriaceae	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
MMS1_k127_2663534_2	58123.JOFJ01000006_gene129	6.608e-80	280.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4EGVC@85012|Streptosporangiales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
MMS1_k127_2663534_3	1313172.YM304_21650	5.054e-76	264.0	COG0500@1|root,COG2226@2|Bacteria,2HG5Z@201174|Actinobacteria,4CN2W@84992|Acidimicrobiia	84992|Acidimicrobiia	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS1_k127_2663534_1	1229780.BN381_50096	1.761e-90	305.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,3UWEG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
MMS1_k127_2664285_2	1246995.AFR_33480	7.189e-37	150.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,4DBY4@85008|Micromonosporales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMS1_k127_2664285_0	525909.Afer_0999	2.736e-59	219.0	COG4097@1|root,COG4097@2|Bacteria,2GQH2@201174|Actinobacteria	201174|Actinobacteria	P	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
MMS1_k127_2664285_1	105420.BBPO01000004_gene1524	9.707e-38	156.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria,2NF9E@228398|Streptacidiphilus	201174|Actinobacteria	H	ApbE family	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMS1_k127_2664584_2	1027371.GOALK_005_00180	9.232e-28	113.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria,4GC5Y@85026|Gordoniaceae	201174|Actinobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
MMS1_k127_2664584_4	1120934.KB894457_gene1422	1.874e-13	76.0	COG3472@1|root,COG3472@2|Bacteria,2IQWS@201174|Actinobacteria,4EF1Z@85010|Pseudonocardiales	201174|Actinobacteria	S	conserved protein (DUF2081)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2664584_3	882083.SacmaDRAFT_3107	1.984e-25	121.0	2DU40@1|root,33NV5@2|Bacteria,2GTWE@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
MMS1_k127_2664584_0	1121877.JQKF01000014_gene55	1.846e-133	436.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria,4CNHB@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMS1_k127_2664584_1	1121877.JQKF01000014_gene56	1.326e-70	241.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CNG3@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
MMS1_k127_2684281_2	525909.Afer_0728	6.63e-114	371.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CMRS@84992|Acidimicrobiia	84992|Acidimicrobiia	HP	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
MMS1_k127_2684281_0	1121877.JQKF01000001_gene1345	1.146e-242	760.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CMX5@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
MMS1_k127_2684281_1	1229780.BN381_10137	5.591e-190	602.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,3UWDW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS1_k127_2684281_3	1132441.KI519455_gene3317	1.349e-110	370.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria,1W8HX@1268|Micrococcaceae	201174|Actinobacteria	S	Peptidase family M20/M25/M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS1_k127_2684281_4	1235755.ANAM01000001_gene572	2.129e-79	277.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,4GXEP@90964|Staphylococcaceae	91061|Bacilli	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	-	-	-	-	-	-	-	-	-	-	PALP
MMS1_k127_2684281_5	1229780.BN381_10171	1.237e-19	91.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,3UWDD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
MMS1_k127_2702173_1	525904.Tter_1680	1.765e-121	403.0	COG1331@1|root,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
MMS1_k127_2702173_2	1121946.AUAX01000005_gene5552	2.775e-77	266.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4DANW@85008|Micromonosporales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS1_k127_2702173_3	1229780.BN381_430061	6.979e-74	262.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,3UWTY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	AMP-binding enzyme	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_2702173_0	1121877.JQKF01000027_gene2463	7.42e-145	464.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4CMXU@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS1_k127_2711225_5	1397666.RS24_00355	2.674e-17	89.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	ahpD	-	-	ko:K04756	-	-	-	-	ko00000	-	-	-	CMD
MMS1_k127_2711225_6	42256.RradSPS_0794	6.509e-11	73.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4CQ0Q@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS1_k127_2711225_0	246194.CHY_2360	4.37e-85	293.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,42FC3@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
MMS1_k127_2711225_1	1246626.BleG1_4023	4.834e-85	294.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	M00239,M00566	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.2	-	-	ABC_tran,oligo_HPY
MMS1_k127_2711225_2	639283.Snov_4270	5.075e-82	282.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2TUCW@28211|Alphaproteobacteria,3EZGX@335928|Xanthobacteraceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	MA20_22700	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS1_k127_2711225_3	1168059.KB899087_gene2086	4.91e-71	255.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,3EYAS@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	MA20_22705	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS1_k127_2711225_4	1089548.KI783301_gene1338	4.572e-43	172.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,3WG5M@539002|Bacillales incertae sedis	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS1_k127_2711569_1	1229780.BN381_290106	1.202e-94	338.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,3UW69@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
MMS1_k127_2711569_0	479433.Caci_3299	3.185e-139	457.0	COG0531@1|root,COG0531@2|Bacteria,2GJ1D@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
MMS1_k127_271399_5	1108045.GORHZ_064_00080	3.593e-08	61.0	2E6D0@1|root,3310N@2|Bacteria,2GQP8@201174|Actinobacteria,4GEC3@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3054)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3054
MMS1_k127_271399_2	1120950.KB892731_gene3810	3.966e-103	353.0	COG0154@1|root,COG0154@2|Bacteria,2GSDB@201174|Actinobacteria,4DPCU@85009|Propionibacteriales	201174|Actinobacteria	J	Amidase	gatA_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS1_k127_271399_4	1313172.YM304_13050	5.32e-22	101.0	2F7CY@1|root,33ZTZ@2|Bacteria,2H76P@201174|Actinobacteria,4CNCM@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_271399_0	525909.Afer_1538	2.907e-201	643.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CMUV@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMS1_k127_271399_1	525909.Afer_1537	8.609e-131	423.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CMVG@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS1_k127_271399_3	525909.Afer_1536	2.377e-24	104.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CMRK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS1_k127_2714615_0	1121877.JQKF01000014_gene15	0.0	1326.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CMSP@84992|Acidimicrobiia	84992|Acidimicrobiia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
MMS1_k127_2714615_2	1121877.JQKF01000014_gene14	1.755e-36	145.0	COG1734@1|root,COG1734@2|Bacteria,2HH4M@201174|Actinobacteria,4CP4R@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2714615_3	1121877.JQKF01000014_gene13	3.639e-30	126.0	COG0597@1|root,COG0597@2|Bacteria,2HGGT@201174|Actinobacteria,4CNE4@84992|Acidimicrobiia	84992|Acidimicrobiia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
MMS1_k127_2714615_1	1229780.BN381_430078	1.966e-67	241.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,3UWB2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMS1_k127_2714615_4	1121877.JQKF01000014_gene11	6.237e-14	72.0	COG0568@1|root,COG0568@2|Bacteria,2H445@201174|Actinobacteria,4CNJ9@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS1_k127_2738138_0	390989.JOEG01000012_gene3435	1.319e-110	368.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4D8P5@85008|Micromonosporales	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
MMS1_k127_2738138_2	1089544.KB912942_gene6704	1.039e-23	113.0	COG2227@1|root,COG2227@2|Bacteria,2I6J5@201174|Actinobacteria,4EE6Q@85010|Pseudonocardiales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS1_k127_2738138_3	1713.JOFV01000006_gene2787	5.847e-08	62.0	COG3402@1|root,COG3402@2|Bacteria,2I2JX@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
MMS1_k127_2738138_1	1121877.JQKF01000037_gene1816	4.563e-76	263.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CN7S@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
MMS1_k127_2740758_0	1246995.AFR_01255	1.07e-144	477.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4DAD5@85008|Micromonosporales	201174|Actinobacteria	E	Oligopeptidase b	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
MMS1_k127_2740758_7	1121877.JQKF01000001_gene1304	7.138e-12	77.0	2AN61@1|root,31D3Y@2|Bacteria,2HGRS@201174|Actinobacteria,4CNUM@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115
MMS1_k127_2740758_1	446466.Cfla_0444	5.931e-124	418.0	COG0465@1|root,COG0465@2|Bacteria,2I9X7@201174|Actinobacteria,4F320@85016|Cellulomonadaceae	201174|Actinobacteria	O	PFAM AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
MMS1_k127_2740758_4	525909.Afer_0540	4.157e-70	242.0	COG1898@1|root,COG1898@2|Bacteria,2HG63@201174|Actinobacteria,4CN7N@84992|Acidimicrobiia	84992|Acidimicrobiia	M	dTDP-4-dehydrorhamnose 3,5-epimerase	rmlC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
MMS1_k127_2740758_6	1313172.YM304_14700	3.342e-47	181.0	COG1235@1|root,COG1235@2|Bacteria,2IJCH@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMS1_k127_2740758_5	1382306.JNIM01000001_gene1862	2.228e-67	242.0	COG0524@1|root,COG0524@2|Bacteria,2G9FA@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
MMS1_k127_2740758_2	749927.AMED_8995	1.015e-118	400.0	COG1457@1|root,COG1457@2|Bacteria,2GJ6B@201174|Actinobacteria,4E0TT@85010|Pseudonocardiales	201174|Actinobacteria	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
MMS1_k127_2740758_3	351607.Acel_0550	6.483e-107	358.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria,4EUA1@85013|Frankiales	201174|Actinobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMS1_k127_2740758_8	29581.BW37_04042	0.0002294	44.0	COG5001@1|root,COG5001@2|Bacteria,1PZR0@1224|Proteobacteria,2VNJ8@28216|Betaproteobacteria,472TX@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
MMS1_k127_275579_2	1121877.JQKF01000004_gene1112	3.958e-37	146.0	COG0558@1|root,COG0558@2|Bacteria,2HGCB@201174|Actinobacteria,4CNAE@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS1_k127_275579_0	1469245.JFBG01000054_gene2100	1.255e-134	441.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1T236@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
MMS1_k127_275579_1	525909.Afer_0653	1.282e-69	239.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CMRW@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
MMS1_k127_2797711_4	390989.JOEG01000018_gene3588	4.193e-16	86.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS1_k127_2797711_1	981369.JQMJ01000004_gene4711	3.134e-191	610.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,2NKEM@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2797711_2	1121877.JQKF01000044_gene1227	5.602e-86	300.0	COG0477@1|root,COG2814@2|Bacteria,2HGMG@201174|Actinobacteria,4CNKA@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2797711_0	322710.Avin_10490	1.064e-234	737.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RMM7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	ybaL	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
MMS1_k127_2797711_3	351607.Acel_1097	1.237e-16	80.0	COG4689@1|root,COG4689@2|Bacteria,2I55Y@201174|Actinobacteria	201174|Actinobacteria	Q	acetoacetate decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	ADC
MMS1_k127_2805581_2	485913.Krac_5515	6.586e-20	100.0	COG0697@1|root,COG0697@2|Bacteria,2G7RS@200795|Chloroflexi	200795|Chloroflexi	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS1_k127_2805581_0	43354.JOIJ01000033_gene2377	5.485e-165	536.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4DY8C@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
MMS1_k127_2805581_1	1211815.CBYP010000061_gene56	5.572e-74	253.0	COG1960@1|root,COG1960@2|Bacteria,2GVSU@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_2814728_4	981369.JQMJ01000004_gene4967	4.544e-21	95.0	2C05E@1|root,3499W@2|Bacteria,2GTF4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2814728_0	1121877.JQKF01000001_gene1416	1.121e-117	394.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,4CP4Y@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_2814728_1	1246995.AFR_26970	1.156e-110	389.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DAB5@85008|Micromonosporales	201174|Actinobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
MMS1_k127_2814728_3	1380393.JHVP01000012_gene2707	7.297e-23	109.0	COG3916@1|root,COG3916@2|Bacteria,2IS03@201174|Actinobacteria	201174|Actinobacteria	QT	Acyl-homoserine-lactone synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2814728_2	1146883.BLASA_0333	1.8e-40	157.0	2F9A4@1|root,341M7@2|Bacteria,2ISUU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
MMS1_k127_2818977_4	1121877.JQKF01000019_gene2579	1.165e-49	190.0	COG0707@1|root,COG0707@2|Bacteria,2GREI@201174|Actinobacteria,4CNGT@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,MGDG_synth
MMS1_k127_2818977_3	298654.FraEuI1c_3800	3.92e-58	210.0	COG0726@1|root,COG0726@2|Bacteria,2GMC2@201174|Actinobacteria,4EVH6@85013|Frankiales	201174|Actinobacteria	G	PFAM Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
MMS1_k127_2818977_1	1121877.JQKF01000019_gene2581	6.559e-68	244.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CNDI@84992|Acidimicrobiia	84992|Acidimicrobiia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMS1_k127_2818977_0	1121877.JQKF01000019_gene2583	6.117e-88	305.0	COG0392@1|root,COG0392@2|Bacteria,2HG5A@201174|Actinobacteria,4CN1V@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
MMS1_k127_2818977_2	518766.Rmar_1244	2.349e-60	225.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,1FIST@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
MMS1_k127_282629_2	469371.Tbis_2123	6.625e-26	113.0	COG2334@1|root,COG2334@2|Bacteria,2GXZI@201174|Actinobacteria,4E5SH@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS1_k127_282629_1	1267533.KB906736_gene1235	3.07e-33	133.0	COG1970@1|root,COG1970@2|Bacteria,3Y58F@57723|Acidobacteria,2JJRP@204432|Acidobacteriia	204432|Acidobacteriia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
MMS1_k127_282629_0	446462.Amir_6075	2.653e-233	738.0	COG0296@1|root,COG3170@1|root,COG0296@2|Bacteria,COG3170@2|Bacteria,2GJ5C@201174|Actinobacteria,4E0S6@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
MMS1_k127_282629_3	1278308.KB907075_gene1244	2.534e-09	63.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4FMJM@85023|Microbacteriaceae	201174|Actinobacteria	G	protein, probably involved in trehalose biosynthesis	mak	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
MMS1_k127_2829925_0	68170.KL590498_gene6842	8.828e-87	312.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4DXMZ@85010|Pseudonocardiales	201174|Actinobacteria	L	helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
MMS1_k127_2829925_3	1229780.BN381_10319	1.092e-41	162.0	COG2050@1|root,COG2050@2|Bacteria,2I11Y@201174|Actinobacteria,3UXR4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS1_k127_2829925_1	1313172.YM304_23330	9.403e-87	293.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4CN0I@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
MMS1_k127_2829925_2	1313172.YM304_21280	5.291e-55	195.0	COG0764@1|root,COG0764@2|Bacteria,2GQWT@201174|Actinobacteria,4CN5K@84992|Acidimicrobiia	84992|Acidimicrobiia	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
MMS1_k127_2829925_4	1121877.JQKF01000024_gene2381	9.509e-21	93.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CMWS@84992|Acidimicrobiia	84992|Acidimicrobiia	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
MMS1_k127_283866_0	1121877.JQKF01000011_gene365	6.333e-173	558.0	COG1001@1|root,COG1001@2|Bacteria,2GNKZ@201174|Actinobacteria,4CN05@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
MMS1_k127_283866_2	543632.JOJL01000027_gene2801	1.353e-35	142.0	2DMC7@1|root,32J0V@2|Bacteria,2I81N@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
MMS1_k127_283866_3	105422.BBPM01000097_gene5227	2.229e-28	122.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria,2NIDX@228398|Streptacidiphilus	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
MMS1_k127_283866_1	1123013.AUIC01000003_gene778	5.861e-99	337.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4FKPA@85023|Microbacteriaceae	201174|Actinobacteria	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
MMS1_k127_2839572_2	1313172.YM304_19690	4.545e-13	73.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,4CN3R@84992|Acidimicrobiia	84992|Acidimicrobiia	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
MMS1_k127_2839572_0	1121877.JQKF01000002_gene1639	3.397e-103	341.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4CMWN@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS1_k127_2839572_1	351607.Acel_0515	4.799e-16	85.0	2BM3X@1|root,33KY1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2839572_4	1184607.AUCHE_05_02300	2.121e-05	55.0	2E4WR@1|root,32ZQT@2|Bacteria,2IP6G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2839572_3	1313172.YM304_18820	1.562e-07	57.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4CNQE@84992|Acidimicrobiia	84992|Acidimicrobiia	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
MMS1_k127_2850495_1	298655.KI912266_gene2207	2.953e-81	277.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4ES40@85013|Frankiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS1_k127_2850495_0	1122939.ATUD01000008_gene2443	1.323e-87	295.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4CQ49@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
MMS1_k127_2850495_4	351607.Acel_0042	6.742e-35	142.0	COG1765@1|root,COG1765@2|Bacteria,2HA74@201174|Actinobacteria	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS1_k127_2850495_5	1089544.KB912942_gene3511	4.837e-21	100.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	DUF2202
MMS1_k127_2850495_3	56107.Cylst_0426	8.913e-42	176.0	COG0823@1|root,COG5276@1|root,COG0823@2|Bacteria,COG5276@2|Bacteria,1GQ7S@1117|Cyanobacteria,1HRXM@1161|Nostocales	1117|Cyanobacteria	Q	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,HemolysinCabind,LVIVD
MMS1_k127_2850495_2	1246995.AFR_04305	4.367e-58	227.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2874115_4	1123024.AUII01000007_gene4815	7.471e-63	222.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4E3XB@85010|Pseudonocardiales	201174|Actinobacteria	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMS1_k127_2874115_0	351607.Acel_0233	9.132e-107	372.0	COG3391@1|root,COG3391@2|Bacteria,2I1IX@201174|Actinobacteria,4EVVE@85013|Frankiales	2|Bacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,DUF4114,Lactonase,Phage-tail_3
MMS1_k127_2874115_10	627192.SLG_30700	6.746e-10	67.0	COG0454@1|root,COG0456@2|Bacteria,1N3QU@1224|Proteobacteria,2UDPY@28211|Alphaproteobacteria,2K5CS@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS1_k127_2874115_7	1160718.SU9_18014	8.34e-36	148.0	COG0346@1|root,COG0346@2|Bacteria,2II17@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS1_k127_2874115_6	309801.trd_0741	6.467e-43	169.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi,27YEQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
MMS1_k127_2874115_1	1260251.SPISAL_01440	1.461e-88	298.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1WW0F@135613|Chromatiales	135613|Chromatiales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
MMS1_k127_2874115_2	1313172.YM304_27710	6.154e-76	263.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CN3V@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
MMS1_k127_2874115_5	1122611.KB903969_gene2370	1.077e-59	222.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4EM4H@85012|Streptosporangiales	201174|Actinobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3,1.1.3.46,1.13.12.4	ko:K00101,ko:K00467,ko:K16422	ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130	-	R00196,R00319,R06633	RC00044,RC00240,RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
MMS1_k127_2874115_11	666681.M301_2005	7.162e-09	63.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,2KMNR@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMS1_k127_2874115_3	985053.VMUT_0103	2.608e-65	235.0	arCOG06008@1|root,arCOG06008@2157|Archaea,2XRQ9@28889|Crenarchaeota	28889|Crenarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_2874115_8	1449355.JQNR01000004_gene2012	1.356e-23	106.0	COG0454@1|root,COG0456@2|Bacteria,2IHU4@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS1_k127_310909_2	397278.JOJN01000009_gene3682	5.576e-91	302.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DNGV@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS1_k127_310909_0	1048339.KB913029_gene3544	4.889e-166	532.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,4ERVR@85013|Frankiales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS1_k127_310909_1	1283283.ATXA01000002_gene2574	1.008e-144	471.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria,4ERU4@85013|Frankiales	201174|Actinobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS1_k127_323321_1	1268303.RHODMAR_0454	2.724e-45	171.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,4FWJ0@85025|Nocardiaceae	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMS1_k127_323321_3	525909.Afer_0997	2.034e-12	71.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
MMS1_k127_323321_0	1121877.JQKF01000002_gene1741	1.138e-95	327.0	COG0477@1|root,COG2814@2|Bacteria,2IFXN@201174|Actinobacteria,4CN8C@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_323321_2	471852.Tcur_0354	2.612e-39	162.0	COG4987@1|root,COG4987@2|Bacteria,2H79B@201174|Actinobacteria,4EFXJ@85012|Streptosporangiales	201174|Actinobacteria	V	TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	cydC	-	-	ko:K06148,ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
MMS1_k127_325778_0	1089545.KB913037_gene4795	1.725e-204	657.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4DXBK@85010|Pseudonocardiales	201174|Actinobacteria	I	TIGRFAM Acetoacetyl-CoA synthase	acsA1	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS1_k127_333424_1	272942.RCAP_rcc03532	2.326e-52	197.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,1FAVS@1060|Rhodobacter	28211|Alphaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
MMS1_k127_333424_2	1193181.BN10_40008	5.52e-37	152.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4FE8K@85021|Intrasporangiaceae	201174|Actinobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
MMS1_k127_333424_3	525909.Afer_1510	4.056e-28	117.0	COG0236@1|root,COG0236@2|Bacteria,2HG9V@201174|Actinobacteria,4CN8D@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
MMS1_k127_333424_0	1313172.YM304_18650	1.29e-100	337.0	COG0416@1|root,COG0416@2|Bacteria,2I8WT@201174|Actinobacteria,4CMRM@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
MMS1_k127_340778_1	266117.Rxyl_1165	2.184e-134	446.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMS1_k127_340778_0	351607.Acel_1322	1.946e-182	587.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria,4ES0V@85013|Frankiales	201174|Actinobacteria	NU	General secretory system II, protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
MMS1_k127_350059_1	1121877.JQKF01000042_gene1917	1.288e-136	441.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
MMS1_k127_350059_2	367299.JOEE01000003_gene3014	3.747e-70	254.0	COG3434@1|root,COG3434@2|Bacteria,2IDSK@201174|Actinobacteria	201174|Actinobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
MMS1_k127_350059_0	1449347.JQLN01000007_gene2154	6.336e-317	982.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,2M1WP@2063|Kitasatospora	201174|Actinobacteria	C	Aconitase C-terminal domain	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMS1_k127_354941_1	637390.AFOH01000047_gene2003	1.432e-57	207.0	COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,1RP6K@1236|Gammaproteobacteria,2NCK9@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.11	ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
MMS1_k127_354941_4	383372.Rcas_3775	3.593e-13	76.0	COG0589@1|root,COG0589@2|Bacteria,2G7ET@200795|Chloroflexi	200795|Chloroflexi	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS1_k127_354941_0	436229.JOEH01000010_gene5144	1.167e-84	285.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,2NF0X@228398|Streptacidiphilus	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS1_k127_354941_2	525909.Afer_1447	2.948e-32	131.0	COG0589@1|root,COG0589@2|Bacteria,2HF8Z@201174|Actinobacteria,4CNUZ@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS1_k127_354941_3	1246484.D479_12258	4.913e-22	100.0	COG1670@1|root,COG1670@2|Bacteria,1V75T@1239|Firmicutes,4HJBK@91061|Bacilli	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS1_k127_367930_3	1229780.BN381_20106	1.982e-35	145.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,3UW8A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
MMS1_k127_367930_2	1313172.YM304_33110	5.71e-44	170.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CN75@84992|Acidimicrobiia	84992|Acidimicrobiia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
MMS1_k127_367930_4	1121877.JQKF01000008_gene657	6.689e-22	102.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CNB1@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	rplY	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
MMS1_k127_367930_0	525909.Afer_1597	2.031e-154	495.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CMVQ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
MMS1_k127_367930_1	1121877.JQKF01000008_gene655	1.67e-86	299.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CMZA@84992|Acidimicrobiia	84992|Acidimicrobiia	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
MMS1_k127_370463_1	1094558.ME5_01118	1.071e-77	264.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,48TCM@772|Bartonellaceae	28211|Alphaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMS1_k127_370463_2	1313172.YM304_33140	5.556e-73	264.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CN31@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG
MMS1_k127_370463_3	1121877.JQKF01000008_gene660	8.043e-43	169.0	COG0760@1|root,COG0760@2|Bacteria,2HGN4@201174|Actinobacteria,4CNNU@84992|Acidimicrobiia	84992|Acidimicrobiia	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
MMS1_k127_370463_0	1229780.BN381_20106	1.012e-256	818.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,3UW8A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
MMS1_k127_381373_6	525909.Afer_1828	2.431e-61	215.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4CNAV@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
MMS1_k127_381373_0	1229780.BN381_100026	1.455e-134	456.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,3UX0X@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C_2,Viral_helicase1
MMS1_k127_381373_1	1229780.BN381_100025	1.526e-111	370.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria,3UWFA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
MMS1_k127_381373_5	1122611.KB903954_gene5681	3.229e-77	276.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,4EFNQ@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMS1_k127_381373_2	1463887.KL589992_gene369	1.635e-97	325.0	COG2013@1|root,COG2013@2|Bacteria,2I9XC@201174|Actinobacteria	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
MMS1_k127_381373_4	525909.Afer_1902	2.561e-93	318.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4CMYP@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DisA bacterial checkpoint controller linker region	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N
MMS1_k127_381373_3	644282.Deba_1135	7.398e-94	326.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
MMS1_k127_381373_7	1121877.JQKF01000035_gene1969	3.104e-28	116.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CMPF@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS1_k127_385120_0	525909.Afer_0723	2.774e-195	620.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CN9K@84992|Acidimicrobiia	84992|Acidimicrobiia	H	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
MMS1_k127_385120_2	525909.Afer_0722	1e-59	212.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,4CNRB@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
MMS1_k127_385120_1	1121877.JQKF01000001_gene1343	9.832e-110	372.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CMUJ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
MMS1_k127_385120_4	1313172.YM304_29090	2.428e-24	111.0	2BJWW@1|root,32E9A@2|Bacteria,2HGG7@201174|Actinobacteria,4CNDN@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_385120_3	263358.VAB18032_06650	9.536e-33	133.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,4DBUU@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS1_k127_399821_6	525909.Afer_0386	7.198e-38	146.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CMZG@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
MMS1_k127_399821_11	1121877.JQKF01000009_gene561	4.17e-10	65.0	COG0690@1|root,COG0690@2|Bacteria,2IK5W@201174|Actinobacteria,4CNX8@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
MMS1_k127_399821_9	1237149.C900_05058	6.221e-18	91.0	COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,47P7T@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS1_k127_399821_8	525909.Afer_0383	8.915e-22	94.0	COG0267@1|root,COG0267@2|Bacteria,2HH2Z@201174|Actinobacteria,4CP34@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L33	-	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
MMS1_k127_399821_5	1229780.BN381_190004	2.795e-48	179.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria,3UXM9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
MMS1_k127_399821_7	1396141.BATP01000032_gene4413	2.726e-30	128.0	COG0122@1|root,COG0122@2|Bacteria,46V2J@74201|Verrucomicrobia	74201|Verrucomicrobia	L	endonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
MMS1_k127_399821_2	525909.Afer_0380	3.384e-71	260.0	2AMJ0@1|root,31CER@2|Bacteria,2I3ZG@201174|Actinobacteria,4CNHF@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_399821_1	525909.Afer_0107	1.305e-159	541.0	COG0030@1|root,COG0438@1|root,COG0030@2|Bacteria,COG0438@2|Bacteria,2HGIU@201174|Actinobacteria,4CNHI@84992|Acidimicrobiia	84992|Acidimicrobiia	JM	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS1_k127_399821_4	1121877.JQKF01000009_gene567	2.147e-51	187.0	COG1666@1|root,COG1666@2|Bacteria,2IFIU@201174|Actinobacteria,4CN1Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
MMS1_k127_399821_10	981369.JQMJ01000004_gene3971	5.472e-17	87.0	COG5083@1|root,COG5083@2|Bacteria,2IFC7@201174|Actinobacteria,2NKQI@228398|Streptacidiphilus	201174|Actinobacteria	S	phosphatidylinositol transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
MMS1_k127_399821_0	35754.JNYJ01000011_gene731	2.859e-166	559.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria,4DBVQ@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
MMS1_k127_399821_3	471852.Tcur_2561	7.631e-54	196.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4EPGJ@85012|Streptosporangiales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17,2.7.1.215,2.7.1.53	ko:K00854,ko:K00862,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00014	R01639,R01901,R07127,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
MMS1_k127_437745_0	525909.Afer_0166	1.784e-211	681.0	COG0021@1|root,COG1494@1|root,COG0021@2|Bacteria,COG1494@2|Bacteria,2GJ1K@201174|Actinobacteria,4CNKC@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX,Transket_pyr,Transketolase_C,Transketolase_N
MMS1_k127_437745_4	1313172.YM304_23000	2.026e-74	261.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CMZI@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
MMS1_k127_437745_5	1110697.NCAST_05_04430	1.02e-72	259.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS1_k127_437745_3	675635.Psed_6246	5.751e-77	273.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4E9TW@85010|Pseudonocardiales	201174|Actinobacteria	T	GAF domain	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
MMS1_k127_437745_2	525909.Afer_0177	9.625e-114	377.0	COG3588@1|root,COG3588@2|Bacteria,2GJ0D@201174|Actinobacteria,4CNJ7@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Fructose-bisphosphate aldolase class-I	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
MMS1_k127_437745_6	525909.Afer_0176	1.606e-51	195.0	COG0583@1|root,COG0583@2|Bacteria,2HF8G@201174|Actinobacteria,4CNGB@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS1_k127_437745_1	105559.Nwat_2772	2.957e-190	601.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1X0B1@135613|Chromatiales	135613|Chromatiales	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
MMS1_k127_440523_4	58123.JOFJ01000001_gene3258	2.012e-28	122.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4EN4W@85012|Streptosporangiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
MMS1_k127_440523_3	649764.HMPREF0762_00225	4.719e-45	167.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CVRY@84998|Coriobacteriia	84998|Coriobacteriia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
MMS1_k127_440523_1	525909.Afer_0864	1.217e-78	271.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4CN03@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
MMS1_k127_440523_2	1229780.BN381_450038	7.775e-59	211.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,3UWI4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
MMS1_k127_440523_0	1394178.AWOO02000100_gene8296	6.274e-158	513.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EHI3@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_442375_2	1121877.JQKF01000001_gene1426	1.415e-78	270.0	COG1903@1|root,COG1903@2|Bacteria,2GM41@201174|Actinobacteria,4CNII@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
MMS1_k127_442375_7	42256.RradSPS_0820	2.067e-39	162.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,2GM8G@201174|Actinobacteria,4CPF4@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,PrmA,TP_methylase
MMS1_k127_442375_0	67315.JOBD01000034_gene4386	6.537e-121	408.0	COG1010@1|root,COG2073@1|root,COG1010@2|Bacteria,COG2073@2|Bacteria,2GMIR@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the precorrin methyltransferase family	cobJ	-	2.1.1.131,3.7.1.12	ko:K13541	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R07772	RC00003,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,TP_methylase
MMS1_k127_442375_9	356851.JOAN01000014_gene2045	4.95e-09	66.0	COG1036@1|root,COG1036@2|Bacteria,2GXHI@201174|Actinobacteria,4DGIY@85008|Micromonosporales	201174|Actinobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
MMS1_k127_442375_8	266117.Rxyl_0645	7.207e-30	126.0	COG2082@1|root,COG2082@2|Bacteria,2GK0B@201174|Actinobacteria,4CQ19@84995|Rubrobacteria	84995|Rubrobacteria	H	Precorrin-8X methylmutase	-	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
MMS1_k127_442375_3	1157638.KB892169_gene6454	7.391e-64	239.0	COG2138@1|root,COG2138@2|Bacteria,2GS51@201174|Actinobacteria	201174|Actinobacteria	P	cobalamin (vitamin B12) biosynthesis CbiX protein	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX,NAD_binding_7
MMS1_k127_442375_1	1157635.KB892024_gene575	1.107e-119	391.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS1_k127_442375_5	1313172.YM304_40420	6.998e-54	199.0	COG2188@1|root,COG2188@2|Bacteria,2HF90@201174|Actinobacteria,4CNBB@84992|Acidimicrobiia	84992|Acidimicrobiia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
MMS1_k127_442375_4	1121877.JQKF01000005_gene900	7.056e-58	212.0	COG1737@1|root,COG1737@2|Bacteria,2GMN2@201174|Actinobacteria,4CNRG@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
MMS1_k127_442375_6	1121877.JQKF01000037_gene1803	2.834e-52	195.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4CNTE@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
MMS1_k127_476676_0	1121877.JQKF01000022_gene2268	1.102e-143	460.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CMWI@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
MMS1_k127_476676_2	1313172.YM304_24220	1.898e-45	173.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CN8K@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
MMS1_k127_476676_1	1121877.JQKF01000022_gene2271	1.422e-107	354.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
MMS1_k127_476676_3	1078020.KEK_03727	1.822e-17	86.0	COG4044@1|root,COG4044@2|Bacteria,2IJGW@201174|Actinobacteria,238KG@1762|Mycobacteriaceae	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
MMS1_k127_479591_2	1121877.JQKF01000012_gene342	5.48e-141	452.0	COG0683@1|root,COG0683@2|Bacteria,2HFKF@201174|Actinobacteria,4CP0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS1_k127_479591_3	1121877.JQKF01000012_gene341	5.689e-141	454.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
MMS1_k127_479591_1	1121877.JQKF01000012_gene340	1.023e-166	529.0	COG4177@1|root,COG4177@2|Bacteria,2H4RR@201174|Actinobacteria	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
MMS1_k127_479591_5	1121877.JQKF01000012_gene339	8.166e-108	359.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CMZ8@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMS1_k127_479591_4	1121877.JQKF01000012_gene338	7.963e-114	371.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CN2Y@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
MMS1_k127_479591_0	1121877.JQKF01000012_gene337	1.42e-251	782.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
MMS1_k127_479591_7	1121877.JQKF01000012_gene336	5.167e-57	206.0	COG1024@1|root,COG1024@2|Bacteria,2GWBT@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS1_k127_479591_6	1121877.JQKF01000012_gene335	7.947e-69	241.0	COG1802@1|root,COG1802@2|Bacteria,2GKH7@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS1_k127_479591_8	1121877.JQKF01000012_gene334	1.39e-44	166.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,4CN6Z@84992|Acidimicrobiia	201174|Actinobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF2437,FAA_hydrolase
MMS1_k127_502249_3	1313172.YM304_05090	8.504e-19	98.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
MMS1_k127_502249_0	1121877.JQKF01000016_gene120	1.807e-304	962.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CMW1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
MMS1_k127_502249_2	1417296.U879_09205	9.734e-120	396.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	ydcT	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
MMS1_k127_502249_1	298654.FraEuI1c_0033	6.7e-121	401.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria,4ESHI@85013|Frankiales	201174|Actinobacteria	E	PFAM extracellular solute-binding protein family 1	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
MMS1_k127_522207_3	222534.KB893783_gene5229	8.683e-66	232.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4ESQ9@85013|Frankiales	201174|Actinobacteria	S	Methyltransferase small domain	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
MMS1_k127_522207_4	405948.SACE_4098	7.569e-51	186.0	COG1595@1|root,COG1595@2|Bacteria,2II47@201174|Actinobacteria,4E3P8@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS1_k127_522207_2	679197.HMPREF9336_01344	3.295e-68	241.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
MMS1_k127_522207_5	1463920.JOGB01000003_gene2757	1.143e-26	116.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
MMS1_k127_522207_0	926564.KI911756_gene6027	1.372e-86	296.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria	201174|Actinobacteria	Q	catechol 1,2-dioxygenase	-	-	1.13.11.1,1.13.11.37	ko:K03381,ko:K04098	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R03891,R04061,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01016,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
MMS1_k127_522207_6	1123023.JIAI01000004_gene8009	0.0003365	45.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4E1U6@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catechol dioxygenase N terminus	chqB	-	1.13.11.1,1.13.11.37	ko:K03381,ko:K04098	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R03891,R04061,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01016,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
MMS1_k127_522207_1	525909.Afer_1816	1.125e-72	254.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CNID@84992|Acidimicrobiia	84992|Acidimicrobiia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	-	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS1_k127_52959_0	1121877.JQKF01000008_gene670	7.258e-292	913.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CMVS@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
MMS1_k127_52959_1	525909.Afer_1762	3.265e-125	410.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CMPD@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMS1_k127_535140_1	525909.Afer_0340	2.734e-91	305.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4CNCZ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
MMS1_k127_535140_2	525909.Afer_0339	5.868e-29	129.0	COG3088@1|root,COG3088@2|Bacteria,2GXH0@201174|Actinobacteria,4CNRN@84992|Acidimicrobiia	84992|Acidimicrobiia	P	subunit of a heme lyase	-	-	-	-	-	-	-	-	-	-	-	-	CcmH
MMS1_k127_535140_3	1121877.JQKF01000016_gene159	3.708e-22	103.0	COG1225@1|root,COG1225@2|Bacteria,2HGRA@201174|Actinobacteria,4CNTT@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Redoxin	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
MMS1_k127_535140_0	1121877.JQKF01000016_gene158	4.943e-106	359.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria,4CMX6@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
MMS1_k127_547630_0	591159.ACEZ01000001_gene6022	1.115e-195	626.0	COG0318@1|root,COG0318@2|Bacteria,2GMWA@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS1_k127_547630_1	1121877.JQKF01000066_gene883	2.703e-68	242.0	COG3064@1|root,COG3064@2|Bacteria,2IPMP@201174|Actinobacteria	201174|Actinobacteria	M	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_558156_2	1121877.JQKF01000003_gene1520	5.212e-175	551.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CMWB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
MMS1_k127_558156_7	1089548.KI783301_gene3087	3.318e-21	100.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,3WEVV@539002|Bacillales incertae sedis	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
MMS1_k127_558156_8	1449353.JQMQ01000005_gene3761	1.384e-09	69.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria,2NIP8@228398|Streptacidiphilus	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
MMS1_k127_558156_4	1223543.GP2_015_01000	4.618e-129	419.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4GBQE@85026|Gordoniaceae	201174|Actinobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
MMS1_k127_558156_0	298654.FraEuI1c_0981	3.238e-210	684.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4ES7U@85013|Frankiales	201174|Actinobacteria	G	PFAM glycosyl transferase, family 35	glgP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
MMS1_k127_558156_5	710111.FraQA3DRAFT_4021	6.578e-43	165.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,4EW28@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
MMS1_k127_558156_6	1123023.JIAI01000002_gene5839	5.215e-30	124.0	COG0346@1|root,COG0346@2|Bacteria,2IHU2@201174|Actinobacteria,4E3VG@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_558156_3	1101188.KI912155_gene2036	7.578e-172	547.0	COG1804@1|root,COG1804@2|Bacteria,2GNF4@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	5.4.1.3	ko:K14470	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09283	RC02480	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
MMS1_k127_558156_1	1108045.GORHZ_183_00270	1.134e-178	565.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4GFX1@85026|Gordoniaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS1_k127_564074_1	2074.JNYD01000024_gene2883	2.577e-39	150.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4E1HQ@85010|Pseudonocardiales	201174|Actinobacteria	E	branched-chain amino acid	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMS1_k127_564074_0	326424.FRAAL2180	0.0	1131.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4ERJ2@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
MMS1_k127_575639_0	1121946.AUAX01000015_gene6095	5.031e-106	368.0	COG0464@1|root,COG0464@2|Bacteria,2I8CR@201174|Actinobacteria,4DBTN@85008|Micromonosporales	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
MMS1_k127_575639_1	1173029.JH980292_gene2247	7.444e-11	70.0	COG5465@1|root,COG5465@2|Bacteria,1G3IY@1117|Cyanobacteria,1HAA9@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
MMS1_k127_580110_3	1313172.YM304_10630	3.965e-06	49.0	COG0712@1|root,COG0712@2|Bacteria,2HGFG@201174|Actinobacteria,4CND3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
MMS1_k127_580110_0	1121877.JQKF01000003_gene1522	8.257e-236	739.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CMTI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
MMS1_k127_580110_1	1313172.YM304_10650	1.237e-68	243.0	COG0224@1|root,COG3743@1|root,COG0224@2|Bacteria,COG3743@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CN1H@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
MMS1_k127_580110_2	525909.Afer_1795	4.251e-66	228.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CMWB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
MMS1_k127_587479_3	1298863.AUEP01000006_gene3218	1.824e-06	53.0	2DMQ5@1|root,32SZ1@2|Bacteria,2I3N2@201174|Actinobacteria,4DQG5@85009|Propionibacteriales	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
MMS1_k127_587479_1	1206730.BAGA01000183_gene3140	1.181e-53	197.0	COG2761@1|root,COG2761@2|Bacteria,2H7YD@201174|Actinobacteria,4FZ5C@85025|Nocardiaceae	201174|Actinobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
MMS1_k127_587479_0	1313172.YM304_21250	2.516e-125	421.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMQK@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
MMS1_k127_587479_2	760192.Halhy_2965	5.213e-37	154.0	COG1232@1|root,COG1232@2|Bacteria,4NEPC@976|Bacteroidetes,1IX8H@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMS1_k127_591376_4	383372.Rcas_3807	7.35e-44	167.0	COG0378@1|root,COG0378@2|Bacteria,2G6EP@200795|Chloroflexi,3760V@32061|Chloroflexia	32061|Chloroflexia	KO	TIGRFAM hydrogenase accessory protein HypB	-	-	-	ko:K03189,ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
MMS1_k127_591376_5	1463909.KL585946_gene1279	1.879e-26	112.0	COG0375@1|root,COG0375@2|Bacteria,2IMJK@201174|Actinobacteria	201174|Actinobacteria	S	Hydrogenase nickel incorporation protein hypA	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
MMS1_k127_591376_7	326427.Cagg_0467	4.836e-16	85.0	COG2427@1|root,COG2427@2|Bacteria,2GAQY@200795|Chloroflexi,3773J@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1641
MMS1_k127_591376_3	675635.Psed_6359	8.231e-69	247.0	COG2207@1|root,COG2207@2|Bacteria,2IBP1@201174|Actinobacteria,4E2SX@85010|Pseudonocardiales	201174|Actinobacteria	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
MMS1_k127_591376_8	882082.SaccyDRAFT_0927	5.081e-15	79.0	COG0298@1|root,COG0298@2|Bacteria,2IRJ9@201174|Actinobacteria,4E5W4@85010|Pseudonocardiales	201174|Actinobacteria	O	Hydrogenase assembly chaperone hypC hupF	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
MMS1_k127_591376_0	309801.trd_1863	5.932e-204	659.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
MMS1_k127_591376_6	1206725.BAFU01000058_gene778	4.725e-22	98.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria,4G2DV@85025|Nocardiaceae	201174|Actinobacteria	O	HupF/HypC family	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
MMS1_k127_591376_1	1283299.AUKG01000001_gene3305	2.543e-91	316.0	COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria,2IIRA@201174|Actinobacteria	201174|Actinobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2
MMS1_k127_591376_9	146922.JOFU01000009_gene959	1.197e-07	55.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
MMS1_k127_591376_2	266940.Krad_2010	2.729e-81	289.0	COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria,2I5QD@201174|Actinobacteria	2|Bacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,HATPase_c,HisKA,PAS,SpoIIE
MMS1_k127_594013_0	1142394.PSMK_24350	8.203e-104	351.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2IX1D@203682|Planctomycetes	203682|Planctomycetes	H	May be the GTPase, regulating ATP sulfurylase activity	cysN	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
MMS1_k127_594013_3	313624.NSP_42900	1.01e-17	94.0	COG2242@1|root,COG2242@2|Bacteria,1G8N2@1117|Cyanobacteria,1HQ5T@1161|Nostocales	1117|Cyanobacteria	H	Methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
MMS1_k127_594013_2	1194165.CAJF01000009_gene819	5.555e-19	101.0	COG2244@1|root,COG2244@2|Bacteria,2H55P@201174|Actinobacteria,4FM0V@85023|Microbacteriaceae	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	ko:K16695	-	-	-	-	ko00000,ko02000	2.A.66.2.7	-	-	Polysacc_synt_3
MMS1_k127_594013_1	1403819.BATR01000002_gene49	1.076e-20	105.0	COG0438@1|root,COG0438@2|Bacteria,46W4S@74201|Verrucomicrobia,2IUTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS1_k127_604032_3	191610.CATYP_08795	3.471e-78	271.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,22JIC@1653|Corynebacteriaceae	201174|Actinobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS1_k127_604032_5	1121877.JQKF01000006_gene957	3.773e-44	168.0	COG0461@1|root,COG0461@2|Bacteria,2HG8J@201174|Actinobacteria,4CN64@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
MMS1_k127_604032_0	1156919.QWC_00115	4.975e-163	525.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,2VNCF@28216|Betaproteobacteria,3T2MP@506|Alcaligenaceae	28216|Betaproteobacteria	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
MMS1_k127_604032_6	1206744.BAGL01000035_gene398	6.918e-23	102.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4G2E5@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
MMS1_k127_604032_4	1027371.GOALK_105_00040	3.213e-52	188.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4GDYG@85026|Gordoniaceae	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03325,ko:K03741	-	-	-	-	ko00000,ko01000,ko02000	2.A.59	-	-	LMWPc
MMS1_k127_604032_1	479434.Sthe_3476	2.256e-105	370.0	COG0022@1|root,COG0022@2|Bacteria,2GAAM@200795|Chloroflexi,27YTG@189775|Thermomicrobia	189775|Thermomicrobia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMS1_k127_604032_2	1169144.KB910946_gene3647	6.578e-104	365.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,1ZCCJ@1386|Bacillus	91061|Bacilli	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	bfmBAA	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07640	E1_dh
MMS1_k127_606070_1	319003.Bra1253DRAFT_05342	8.096e-47	188.0	COG1401@1|root,COG1401@2|Bacteria,1MYQM@1224|Proteobacteria,2TT5S@28211|Alphaproteobacteria,3JUBB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	AAA domain (dynein-related subfamily)	-	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5,DUF4357
MMS1_k127_606070_4	1172180.KB911788_gene2610	4.63e-07	62.0	COG4268@1|root,COG4268@2|Bacteria,2GKET@201174|Actinobacteria	201174|Actinobacteria	V	5-methylcytosine restriction system	-	-	-	ko:K19147	-	-	-	-	ko00000,ko02048	-	-	-	McrBC
MMS1_k127_606070_3	716544.wcw_0183	2.56e-13	76.0	COG2801@1|root,COG2801@2|Bacteria,2JHEV@204428|Chlamydiae	204428|Chlamydiae	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
MMS1_k127_606070_2	1123052.AUDF01000005_gene1101	2.56e-43	171.0	2BKIQ@1|root,32EZW@2|Bacteria,2GY76@201174|Actinobacteria,4FT6W@85023|Microbacteriaceae	201174|Actinobacteria	S	FRG domain	-	-	-	-	-	-	-	-	-	-	-	-	FRG
MMS1_k127_606070_0	530564.Psta_3422	1.215e-82	288.0	COG0210@1|root,COG2026@1|root,COG0210@2|Bacteria,COG2026@2|Bacteria,2IXFN@203682|Planctomycetes	203682|Planctomycetes	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
MMS1_k127_611681_5	1123073.KB899242_gene1238	1.89e-18	96.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1X313@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
MMS1_k127_611681_3	1313172.YM304_20790	2.829e-85	294.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CMY2@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMS1_k127_611681_2	525909.Afer_1664	4.812e-90	311.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4CN30@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
MMS1_k127_611681_1	1313172.YM304_20800	2.071e-96	325.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CMYC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
MMS1_k127_611681_0	1313172.YM304_20810	9.919e-106	362.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CMTH@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS1_k127_611681_4	1123267.JONN01000002_gene84	2.569e-36	143.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2TR81@28211|Alphaproteobacteria,2K0CM@204457|Sphingomonadales	204457|Sphingomonadales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMS1_k127_627326_3	525909.Afer_1162	1.942e-13	78.0	2B87Q@1|root,321GA@2|Bacteria,2HGVA@201174|Actinobacteria,4CNW4@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_627326_1	525909.Afer_1161	1.901e-64	238.0	COG0644@1|root,COG0644@2|Bacteria,2GMH9@201174|Actinobacteria,4CNQ0@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
MMS1_k127_627326_2	525909.Afer_1159	1.027e-51	190.0	COG0431@1|root,COG0431@2|Bacteria,2HH4J@201174|Actinobacteria,4CP4P@84992|Acidimicrobiia	84992|Acidimicrobiia	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
MMS1_k127_627326_0	525909.Afer_1130	1.085e-137	453.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,4CP4Y@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_628278_1	886293.Sinac_0262	2.754e-23	103.0	COG1089@1|root,COG1089@2|Bacteria,2IZEA@203682|Planctomycetes	203682|Planctomycetes	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS1_k127_628278_0	1121877.JQKF01000001_gene1365	1.904e-69	265.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4CN7G@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
MMS1_k127_636194_7	928724.SacglDRAFT_03036	2.548e-14	73.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4E0AX@85010|Pseudonocardiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaC	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS1_k127_636194_5	285535.JOEY01000030_gene6986	1.016e-31	134.0	COG1309@1|root,COG1309@2|Bacteria,2IA24@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,TetR_N
MMS1_k127_636194_0	1121877.JQKF01000097_gene2311	2.836e-206	651.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_636194_4	582515.KR51_00032820	9.171e-35	149.0	COG1451@1|root,COG1451@2|Bacteria,1G6GG@1117|Cyanobacteria	1117|Cyanobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
MMS1_k127_636194_1	1242864.D187_009653	2.163e-203	652.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,42Z4I@68525|delta/epsilon subdivisions,2WUEY@28221|Deltaproteobacteria,2YW9D@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
MMS1_k127_636194_2	1121877.JQKF01000038_gene1826	4.693e-104	362.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2IBIC@201174|Actinobacteria,4CNJT@84992|Acidimicrobiia	84992|Acidimicrobiia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMS1_k127_636194_3	909613.UO65_2559	1.292e-77	268.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4DZX7@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	rifO	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS1_k127_636194_6	882083.SacmaDRAFT_2578	5.556e-28	117.0	COG0640@1|root,COG0640@2|Bacteria,2IKPW@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
MMS1_k127_636194_8	58344.JOEL01000023_gene1115	1.396e-05	57.0	COG4447@1|root,COG4447@2|Bacteria,2GMJN@201174|Actinobacteria	201174|Actinobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
MMS1_k127_639413_1	525909.Afer_1846	5.708e-59	206.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CNG0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMS1_k127_639413_0	675635.Psed_6538	3.148e-155	510.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4DZME@85010|Pseudonocardiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
MMS1_k127_647006_3	1157637.KB892092_gene6927	6.181e-67	234.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMS1_k127_647006_2	1146883.BLASA_0455	4.516e-67	241.0	COG4177@1|root,COG4177@2|Bacteria,2I8MK@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMS1_k127_647006_0	1157637.KB892092_gene6925	3.234e-115	387.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	ilvJ	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMS1_k127_647006_1	1121877.JQKF01000001_gene1293	4.702e-78	270.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4CN0C@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
MMS1_k127_647006_4	1121877.JQKF01000001_gene1294	6.509e-27	116.0	COG3255@1|root,COG3255@2|Bacteria,2HGRI@201174|Actinobacteria,4CNUA@84992|Acidimicrobiia	84992|Acidimicrobiia	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
MMS1_k127_666820_0	525909.Afer_0444	5.601e-129	415.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CMU0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMS1_k127_666820_3	1121877.JQKF01000009_gene506	1.149e-45	167.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CN66@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
MMS1_k127_666820_1	1229780.BN381_130036	2.961e-104	348.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,3UWA4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
MMS1_k127_666820_4	867903.ThesuDRAFT_02301	1.852e-38	151.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WDCE@538999|Clostridiales incertae sedis	186801|Clostridia	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
MMS1_k127_666820_2	1121017.AUFG01000025_gene183	1.692e-83	293.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4FFX8@85021|Intrasporangiaceae	201174|Actinobacteria	V	Multidrug transporter MatE	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
MMS1_k127_666820_6	1007096.BAGW01000010_gene2210	4.855e-06	57.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,2N6PW@216572|Oscillospiraceae	186801|Clostridia	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
MMS1_k127_666820_5	176090.SSIN_1429	6.617e-29	123.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli	91061|Bacilli	M	ATPase or kinase	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
MMS1_k127_669470_5	1313172.YM304_15380	3.323e-54	201.0	COG3394@1|root,COG3394@2|Bacteria,2HG9M@201174|Actinobacteria,4CN7Z@84992|Acidimicrobiia	84992|Acidimicrobiia	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
MMS1_k127_669470_0	1121877.JQKF01000001_gene1297	1.557e-274	858.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CMRD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS1_k127_669470_6	1121877.JQKF01000001_gene1298	9.803e-41	160.0	COG1266@1|root,COG1266@2|Bacteria,2H0BD@201174|Actinobacteria,4CNBE@84992|Acidimicrobiia	84992|Acidimicrobiia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS1_k127_669470_3	1229780.BN381_10199	1.295e-119	414.0	COG5617@1|root,COG5617@2|Bacteria,2H32H@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_669470_2	525909.Afer_1768	1.745e-183	587.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CMU2@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS1_k127_669470_7	1229780.BN381_10201	1.406e-17	84.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
MMS1_k127_669470_4	1121877.JQKF01000008_gene667	9.24e-99	335.0	COG2222@1|root,COG2222@2|Bacteria,2IN5A@201174|Actinobacteria,4CNJ1@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
MMS1_k127_669470_1	1121877.JQKF01000008_gene668	1.457e-197	623.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4CMTB@84992|Acidimicrobiia	84992|Acidimicrobiia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMS1_k127_680757_0	1108045.GORHZ_168_00390	1.547e-26	114.0	28XNX@1|root,2ZJJV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_680757_1	367299.JOEE01000010_gene3375	1.276e-24	107.0	COG3450@1|root,COG3450@2|Bacteria,2IHPC@201174|Actinobacteria,4FJSH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
MMS1_k127_701194_1	981369.JQMJ01000004_gene1671	3.045e-122	400.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,2NH2M@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_701194_2	1449068.JMLQ01000010_gene3884	1.47e-27	121.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4FUQR@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
MMS1_k127_701194_0	525909.Afer_0479	4.56e-236	747.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CMS4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
MMS1_k127_71029_7	1227352.C173_29996	6.155e-14	73.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HEJ8@91061|Bacilli,274PV@186822|Paenibacillaceae	91061|Bacilli	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS1_k127_71029_3	1121877.JQKF01000002_gene1746	1.877e-93	327.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CN74@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
MMS1_k127_71029_0	525909.Afer_0493	1.542e-211	686.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CMSA@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family M1 domain	-	-	-	ko:K08776	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
MMS1_k127_71029_4	1007104.SUS17_2920	1.232e-63	230.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2K0DX@204457|Sphingomonadales	204457|Sphingomonadales	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
MMS1_k127_71029_5	1111479.AXAR01000001_gene389	7.346e-42	165.0	COG0584@1|root,COG0584@2|Bacteria,1TQ3Y@1239|Firmicutes,4HAI9@91061|Bacilli,279TU@186823|Alicyclobacillaceae	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
MMS1_k127_71029_2	1229780.BN381_10079	6.989e-99	334.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,3UW6U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
MMS1_k127_71029_1	1313172.YM304_12590	4.446e-164	532.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CMSH@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMS1_k127_714383_0	28042.GU90_16820	1.059e-239	766.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E2BB@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	cutL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS1_k127_714383_1	868864.Dester_0768	7.542e-54	192.0	COG0148@1|root,COG0148@2|Bacteria,2G3N8@200783|Aquificae	200783|Aquificae	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMS1_k127_75404_0	1229780.BN381_150069	4.731e-254	796.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,3UX6U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	B12 binding domain	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
MMS1_k127_75404_2	1121877.JQKF01000018_gene2526	4.841e-36	146.0	COG2199@1|root,COG3706@2|Bacteria,2H9Y8@201174|Actinobacteria,4CNRT@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMS1_k127_75404_1	525909.Afer_0231	1.244e-56	198.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMPB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMS1_k127_758129_0	314345.SPV1_00345	6.073e-236	759.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria	1224|Proteobacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
MMS1_k127_758129_1	479432.Sros_6003	2.55e-143	467.0	COG1012@1|root,COG1012@2|Bacteria,2GMNB@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde dehydrogenase	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMS1_k127_761416_3	644548.SCNU_14916	3.003e-57	209.0	28HG7@1|root,2Z7S3@2|Bacteria,2GMJK@201174|Actinobacteria,4GCQV@85026|Gordoniaceae	201174|Actinobacteria	S	DinB superfamily	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MDMPI_N,Wyosine_form
MMS1_k127_761416_0	369723.Strop_2599	6.858e-153	492.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DBBX@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS1_k127_761416_4	1120950.KB892756_gene6676	4.788e-18	97.0	2DT0G@1|root,33I5Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_761416_2	1408224.SAMCCGM7_c1794	2.739e-68	254.0	COG1984@1|root,COG2049@1|root,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU9H@1224|Proteobacteria,2U0J4@28211|Alphaproteobacteria,4BBA7@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	COG2049 Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B,CT_C_D
MMS1_k127_761416_1	1150399.AQYK01000002_gene3030	2.043e-72	253.0	COG1540@1|root,COG1540@2|Bacteria,2GJA1@201174|Actinobacteria,4FNFE@85023|Microbacteriaceae	201174|Actinobacteria	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
MMS1_k127_761416_5	1121468.AUBR01000001_gene448	0.000307	45.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42GQK@68295|Thermoanaerobacterales	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS1_k127_790236_2	469371.Tbis_2123	4.5e-76	258.0	COG2334@1|root,COG2334@2|Bacteria,2GXZI@201174|Actinobacteria,4E5SH@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS1_k127_790236_5	68260.JOAY01000017_gene3521	8.964e-65	227.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS1_k127_790236_3	1157637.KB892090_gene6163	1.161e-68	248.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS1_k127_790236_6	869210.Marky_0363	3.18e-13	73.0	COG0607@1|root,COG0607@2|Bacteria,1WJ03@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS1_k127_790236_1	351607.Acel_1472	6.451e-91	313.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS1_k127_790236_4	1313172.YM304_12550	1.177e-65	238.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4CN5Q@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
MMS1_k127_790236_7	1121877.JQKF01000013_gene256	1.051e-07	59.0	2ARDU@1|root,31GPX@2|Bacteria,2HGXA@201174|Actinobacteria,4CNXG@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_790236_0	1121877.JQKF01000013_gene255	5.309e-130	424.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CMT9@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Protein of unknown function (DUF933)	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
MMS1_k127_790414_4	525909.Afer_0074	1.244e-56	213.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4CNDE@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMS1_k127_790414_9	211114.JOEF01000009_gene1744	6.564e-16	83.0	COG1846@1|root,COG1846@2|Bacteria,2IQNM@201174|Actinobacteria,4E61C@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS1_k127_790414_3	450851.PHZ_p0309	9.148e-93	321.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2KJZ0@204458|Caulobacterales	204458|Caulobacterales	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS1_k127_790414_2	525909.Afer_0076	1.195e-174	558.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4CN9X@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
MMS1_k127_790414_5	521011.Mpal_1435	5.831e-37	143.0	COG0537@1|root,arCOG00419@2157|Archaea,2Y0J5@28890|Euryarchaeota,2NA21@224756|Methanomicrobia	224756|Methanomicrobia	F	PFAM histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
MMS1_k127_790414_8	1116232.AHBF01000031_gene6546	4.004e-25	108.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS1_k127_790414_6	653045.Strvi_5942	3.308e-33	135.0	COG1846@1|root,COG1846@2|Bacteria,2IBDP@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMS1_k127_790414_7	525909.Afer_1887	4.665e-31	132.0	COG2385@1|root,COG2385@2|Bacteria,2HGNA@201174|Actinobacteria,4CNPA@84992|Acidimicrobiia	84992|Acidimicrobiia	D	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_790414_1	1240349.ANGC01000021_gene3492	1.931e-209	664.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4FWBE@85025|Nocardiaceae	201174|Actinobacteria	E	glutamate synthase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
MMS1_k127_790414_0	298655.KI912267_gene7175	0.0	1899.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4ERS2@85013|Frankiales	201174|Actinobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
MMS1_k127_792659_3	1121877.JQKF01000002_gene1764	2.055e-11	71.0	COG1259@1|root,COG1259@2|Bacteria,2HH49@201174|Actinobacteria,4CP4A@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bifunctional nuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNase-RNase
MMS1_k127_792659_1	1120950.KB892741_gene2668	6.318e-78	272.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4DNYY@85009|Propionibacteriales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	pdxB	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS1_k127_792659_2	1463853.JOHW01000008_gene818	8.6e-51	186.0	COG0491@1|root,COG0491@2|Bacteria,2GJ6X@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS1_k127_792659_0	340177.Cag_0847	1.226e-193	618.0	COG0507@1|root,COG0507@2|Bacteria,1FEYG@1090|Chlorobi	1090|Chlorobi	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
MMS1_k127_798975_3	1121877.JQKF01000016_gene124	2.946e-92	305.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CMRQ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_798975_2	1183377.Py04_1117	1.326e-95	332.0	COG0215@1|root,arCOG00486@2157|Archaea,2XTRY@28890|Euryarchaeota,243CK@183968|Thermococci	183968|Thermococci	J	Cysteinyl-tRNA synthetase	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
MMS1_k127_798975_0	269800.Tfu_1936	4.255e-311	979.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4EIDQ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
MMS1_k127_798975_1	1121877.JQKF01000007_gene1050	3.732e-142	465.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4CNMY@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS1_k127_798975_4	1906.SFRA_32250	1.975e-20	92.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMS1_k127_799574_3	272562.CA_C1304	1.097e-05	56.0	COG1579@1|root,COG1579@2|Bacteria,1VKTP@1239|Firmicutes,24JFI@186801|Clostridia,36JGI@31979|Clostridiaceae	186801|Clostridia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
MMS1_k127_799574_0	626939.HMPREF9443_01651	3.295e-96	341.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
MMS1_k127_799574_1	525909.Afer_1492	3.238e-29	120.0	COG0694@1|root,COG0694@2|Bacteria,2HGE4@201174|Actinobacteria,4CNCF@84992|Acidimicrobiia	84992|Acidimicrobiia	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
MMS1_k127_799574_2	525909.Afer_1491	8.308e-26	108.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4CN6U@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
MMS1_k127_801939_0	1219581.HMPREF1628_07010	3.849e-262	816.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4D5D0@85005|Actinomycetales	201174|Actinobacteria	C	Pyridine nucleotide-disulfide oxidoreductase	preT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,NAD_binding_8,Pyr_redox_2,Pyr_redox_3
MMS1_k127_801939_1	345341.KUTG_00476	3.112e-166	529.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS1_k127_801939_2	1123487.KB892840_gene75	8.683e-155	502.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria,2KVEF@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyruvate:ferredoxin oxidoreductase core domain II	padG	-	1.2.1.58	ko:K18355	ko00360,map00360	-	R02450	RC00004,RC02860	br01601,ko00000,ko00001,ko01000	-	-	-	PFOR_II,POR_N
MMS1_k127_801939_3	864051.BurJ1DRAFT_4544	3.427e-69	241.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2VQ8C@28216|Betaproteobacteria,1KKPN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.1.58,1.2.7.1	ko:K00172,ko:K18357	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
MMS1_k127_827206_2	1229780.BN381_100153	5.566e-08	63.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_827206_0	525909.Afer_0027	4.724e-115	391.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CN0A@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMS1_k127_827206_1	1313172.YM304_42740	7.615e-59	215.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4CN2K@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
MMS1_k127_836886_2	1313172.YM304_07620	7.118e-51	194.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4CMU5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_836886_1	1313172.YM304_07520	1.675e-162	524.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4CMSG@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mg-chelatase subunit ChlI	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
MMS1_k127_836886_0	1121877.JQKF01000016_gene131	1.247e-201	631.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CN0E@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS1_k127_837046_0	1121877.JQKF01000063_gene2339	4.325e-144	468.0	COG1879@1|root,COG1879@2|Bacteria,2GKZB@201174|Actinobacteria	201174|Actinobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
MMS1_k127_837046_2	1121877.JQKF01000063_gene2340	1.21e-109	367.0	COG1172@1|root,COG1172@2|Bacteria,2HFVN@201174|Actinobacteria,4CP1T@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10561	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	BPD_transp_2
MMS1_k127_837046_1	675635.Psed_5473	7.942e-140	456.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4DZJ7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	cyp	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
MMS1_k127_837046_3	263358.VAB18032_29821	4.011e-15	85.0	COG3469@1|root,COG3469@2|Bacteria,2GJH0@201174|Actinobacteria,4DABE@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	chiA	-	-	-	-	-	-	-	-	-	-	-	CBM_2,CBM_4_9,CBM_5_12,Glyco_hydro_18,fn3
MMS1_k127_837250_0	502025.Hoch_4258	8.717e-130	438.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,437TW@68525|delta/epsilon subdivisions,2X33B@28221|Deltaproteobacteria,2YU23@29|Myxococcales	28221|Deltaproteobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
MMS1_k127_83949_0	1121877.JQKF01000003_gene1445	9.892e-224	704.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CNJW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMS1_k127_83949_1	1121877.JQKF01000003_gene1446	3.88e-202	643.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CMQA@84992|Acidimicrobiia	84992|Acidimicrobiia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS1_k127_83949_4	1463858.JOHR01000014_gene5277	6.811e-28	119.0	COG3152@1|root,COG3152@2|Bacteria,2IQHK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
MMS1_k127_83949_2	235985.BBPN01000023_gene2615	1.269e-172	553.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,2NHQV@228398|Streptacidiphilus	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS1_k127_83949_3	1246448.ANAZ01000024_gene2905	1.629e-31	128.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4EID9@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
MMS1_k127_848812_0	253839.SSNG_00695	4.463e-113	376.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
MMS1_k127_848812_1	1028800.RG540_CH13520	2.381e-63	228.0	COG0500@1|root,COG2226@2|Bacteria,1REVA@1224|Proteobacteria,2U929@28211|Alphaproteobacteria,4BC95@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS1_k127_848812_2	585531.HMPREF0063_11853	1.155e-15	79.0	2CAFG@1|root,32ZDZ@2|Bacteria,2I800@201174|Actinobacteria,4DRHQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
MMS1_k127_848812_3	557599.MKAN_20275	3.327e-08	58.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,2336F@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
MMS1_k127_855930_11	67281.JNZZ01000034_gene757	5.502e-14	82.0	COG0464@1|root,COG0464@2|Bacteria,2I8CR@201174|Actinobacteria,41A69@629295|Streptomyces griseus group	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
MMS1_k127_855930_10	1209984.BN978_01820	4.541e-29	121.0	COG1219@1|root,COG1219@2|Bacteria,2IQUB@201174|Actinobacteria,23A9N@1762|Mycobacteriaceae	201174|Actinobacteria	O	but contains zinc binding domain found at the N-terminus of the ClpX protein. ClpX is an ATPase which functions both as a substrate specificity component of the ClpXP protease and as a molecular chaperone	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	zf-C4_ClpX
MMS1_k127_855930_5	110319.CF8_0548	1.807e-55	197.0	COG1373@1|root,COG1373@2|Bacteria,2GK4E@201174|Actinobacteria,4DU99@85009|Propionibacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS1_k127_855930_9	110319.CF8_0548	1.669e-34	134.0	COG1373@1|root,COG1373@2|Bacteria,2GK4E@201174|Actinobacteria,4DU99@85009|Propionibacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS1_k127_855930_0	1120950.KB892790_gene2051	2.67e-182	589.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,2GYM5@201174|Actinobacteria,4DSZ1@85009|Propionibacteriales	201174|Actinobacteria	C	Nickel-dependent hydrogenase	hycE	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
MMS1_k127_855930_2	1120950.KB892790_gene2050	1.129e-143	471.0	COG0651@1|root,COG0651@2|Bacteria,2HAC7@201174|Actinobacteria,4DTN6@85009|Propionibacteriales	201174|Actinobacteria	CP	Proton-conducting membrane transporter	hycQ	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
MMS1_k127_855930_7	1120950.KB892790_gene2049	1.468e-51	190.0	COG4237@1|root,COG4237@2|Bacteria,2HQ3P@201174|Actinobacteria,4DUPZ@85009|Propionibacteriales	201174|Actinobacteria	C	Hydrogenase 4 membrane	hycP	GO:0008150,GO:0040007	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
MMS1_k127_855930_3	40571.JOEA01000003_gene3516	2.28e-83	295.0	COG0650@1|root,COG0650@2|Bacteria,2GJFM@201174|Actinobacteria,4E09J@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH dehydrogenase	hycD	-	-	ko:K12138	-	-	-	-	ko00000,ko01000	-	-	-	NADHdh
MMS1_k127_855930_1	345341.KUTG_09509	1.787e-181	590.0	COG0651@1|root,COG0651@2|Bacteria,2HAC7@201174|Actinobacteria,4E1K9@85010|Pseudonocardiales	201174|Actinobacteria	CP	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
MMS1_k127_855930_6	419947.MRA_0086	1.561e-52	193.0	COG3260@1|root,COG3260@2|Bacteria,2IDTD@201174|Actinobacteria,238TU@1762|Mycobacteriaceae	201174|Actinobacteria	C	oxidoreductase	hycG	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
MMS1_k127_855930_8	1133850.SHJG_1516	5.158e-36	141.0	COG0640@1|root,COG0640@2|Bacteria,2IKK2@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
MMS1_k127_855930_4	1306990.BARG01000034_gene4088	2.476e-57	208.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	lipN	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
MMS1_k127_859154_4	469383.Cwoe_2510	8.591e-10	62.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CR38@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
MMS1_k127_859154_0	1121877.JQKF01000023_gene2247	4.08e-52	205.0	COG1999@1|root,COG1999@2|Bacteria,2HGIC@201174|Actinobacteria,4CNGE@84992|Acidimicrobiia	84992|Acidimicrobiia	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_859154_2	1246995.AFR_04305	1.13e-23	118.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_859154_5	1463887.KL589982_gene4677	3.792e-09	70.0	COG1572@1|root,COG3391@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,DUF4842,Peptidase_S8,VCBS,fn3
MMS1_k127_859154_3	1100721.ALKO01000022_gene1900	6.058e-14	86.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Endotoxin_C,HemolysinCabind,Lectin_C
MMS1_k127_859154_1	298653.Franean1_6014	1.57e-45	174.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4ET5U@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS1_k127_860621_6	1089544.KB912942_gene1783	1.639e-32	137.0	COG1073@1|root,COG1073@2|Bacteria,2IFI1@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS1_k127_860621_3	105425.BBPL01000059_gene5044	2.561e-58	214.0	arCOG03842@1|root,30WW9@2|Bacteria,2IDJ1@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF929
MMS1_k127_860621_4	1229780.BN381_100119	1.793e-49	188.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,3UXHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
MMS1_k127_860621_1	1229780.BN381_100120	6.347e-85	296.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,3UX1R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
MMS1_k127_860621_9	1313172.YM304_41120	5.085e-26	114.0	COG0745@1|root,COG0745@2|Bacteria	1313172.YM304_41120|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_860621_10	436229.JOEH01000009_gene4564	0.0004185	44.0	COG1609@1|root,COG1609@2|Bacteria,2GSWK@201174|Actinobacteria,2NJKA@228398|Streptacidiphilus	201174|Actinobacteria	K	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Phage_int_SAM_3,Phage_integrase
MMS1_k127_860621_8	263820.PTO0102	4.782e-27	128.0	COG3420@1|root,arCOG02519@2157|Archaea	2157|Archaea	P	Nitrous oxidase accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CarboxypepD_reg,NosD,PKD,Pectate_lyase_3,Peptidase_S8
MMS1_k127_860621_2	1246995.AFR_04305	6.666e-74	271.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_860621_5	1121877.JQKF01000008_gene623	2.896e-46	175.0	COG1802@1|root,COG1802@2|Bacteria,2GMI2@201174|Actinobacteria,4CNUN@84992|Acidimicrobiia	84992|Acidimicrobiia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS1_k127_860621_0	1394178.AWOO02000076_gene1954	1.496e-160	522.0	COG0318@1|root,COG0318@2|Bacteria,2IBYI@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS1_k127_860621_7	1121877.JQKF01000014_gene5	5.028e-29	126.0	COG2345@1|root,COG2345@2|Bacteria,2HGTI@201174|Actinobacteria,4CNV8@84992|Acidimicrobiia	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS1_k127_863671_1	1089544.KB912942_gene1056	5.25e-267	833.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4DX6T@85010|Pseudonocardiales	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
MMS1_k127_863671_2	1123320.KB889723_gene7516	8.489e-207	668.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
MMS1_k127_863671_0	711393.AYRX01000017_gene3081	4.481e-298	941.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria	201174|Actinobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
MMS1_k127_863671_5	1449069.JMLO01000001_gene1588	5.871e-17	88.0	COG1993@1|root,COG1993@2|Bacteria,2IM7J@201174|Actinobacteria,4G1XZ@85025|Nocardiaceae	201174|Actinobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
MMS1_k127_863671_4	235985.BBPN01000030_gene1984	6.087e-26	113.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,2NIHG@228398|Streptacidiphilus	201174|Actinobacteria	D	CrcB-like protein, Camphor Resistance (CrcB)	crcB1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
MMS1_k127_863671_7	1463857.JOFZ01000014_gene1141	1.41e-10	71.0	COG1993@1|root,COG1993@2|Bacteria,2IM7J@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
MMS1_k127_863671_3	1288083.AUKR01000017_gene2485	7.929e-33	131.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB2	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
MMS1_k127_863671_6	357808.RoseRS_1743	3.545e-15	85.0	COG4932@1|root,COG4932@2|Bacteria,2G7MG@200795|Chloroflexi,376NW@32061|Chloroflexia	32061|Chloroflexia	M	PFAM Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_915869_1	414996.IL38_09685	4.934e-37	149.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,407MU@622450|Actinopolysporales	201174|Actinobacteria	H	AIR synthase related protein, N-terminal domain	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
MMS1_k127_915869_0	469383.Cwoe_4211	4.904e-202	636.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
MMS1_k127_919087_0	1283287.KB822586_gene859	2.526e-241	756.0	COG0531@1|root,COG0531@2|Bacteria,2GIWQ@201174|Actinobacteria,4DNNH@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS1_k127_919087_1	2002.JOEQ01000024_gene195	3.849e-45	174.0	COG2186@1|root,COG2186@2|Bacteria,2GKJM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS1_k127_919087_2	1476876.JOJO01000011_gene3421	1.141e-07	58.0	COG2186@1|root,COG2186@2|Bacteria,2IAQ9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
MMS1_k127_940631_2	479433.Caci_7870	1.646e-38	153.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
MMS1_k127_940631_0	1123501.KB902297_gene3616	2.208e-65	235.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
MMS1_k127_940631_1	68199.JNZO01000004_gene1609	9.934e-39	155.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	bioH	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS1_k127_96106_2	1313172.YM304_19350	3.707e-27	113.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CNPK@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS1_k127_96106_4	1379270.AUXF01000001_gene2453	8.114e-09	61.0	2FKCY@1|root,34C0C@2|Bacteria,1ZU3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS1_k127_96106_1	1121877.JQKF01000004_gene1085	9.395e-61	213.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CN5M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
MMS1_k127_96106_0	75379.Tint_1179	2.206e-88	319.0	COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria,1RA51@1224|Proteobacteria,2VQRX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,Protoglobin
MMS1_k127_96106_3	525909.Afer_1254	5.068e-11	69.0	COG0095@1|root,COG0095@2|Bacteria,2HG9N@201174|Actinobacteria,4CN81@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
MMS1_k127_978512_3	443144.GM21_0500	6.618e-60	218.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
MMS1_k127_978512_0	1121877.JQKF01000014_gene32	7.086e-123	417.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CN0Q@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
MMS1_k127_978512_2	1121472.AQWN01000005_gene2387	3.716e-99	342.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS1_k127_978512_1	1121877.JQKF01000014_gene30	1.445e-101	343.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CMYF@84992|Acidimicrobiia	84992|Acidimicrobiia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
## 1611 queries scanned
## Total time (seconds): 31.671960592269897
## Rate: 50.87 q/s