## Fri Nov 15 20:35:37 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin17/MMS_3_bin.57.fa -m mmseqs --itype genome -o MMS_3_bin.57 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/MMS_3_bin.57 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
MMS3_k127_101086_2	1267535.KB906767_gene1544	2.926e-71	247.0	COG0436@1|root,COG0436@2|Bacteria,3Y3DG@57723|Acidobacteria,2JMAM@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
MMS3_k127_101086_3	402881.Plav_1338	2.062e-36	141.0	COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,2UEV4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
MMS3_k127_101086_1	1267535.KB906767_gene3285	4.165e-115	383.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,3Y4AH@57723|Acidobacteria,2JJ4R@204432|Acidobacteriia	204432|Acidobacteriia	K	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
MMS3_k127_101086_0	1340493.JNIF01000003_gene2373	4.12e-149	489.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
MMS3_k127_107004_1	335543.Sfum_3563	1.934e-58	212.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_107004_2	639030.JHVA01000001_gene3458	3.5e-45	182.0	COG2856@1|root,COG2856@2|Bacteria,3Y3ZJ@57723|Acidobacteria,2JIJ0@204432|Acidobacteriia	204432|Acidobacteriia	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_107004_0	204669.Acid345_4656	1.588e-248	783.0	COG0272@1|root,COG0272@2|Bacteria,3Y2UR@57723|Acidobacteria,2JHN1@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMS3_k127_108463_2	4565.Traes_5DL_5F4977E85.2	8.963e-05	47.0	KOG1721@1|root,KOG1721@2759|Eukaryota,37PT4@33090|Viridiplantae,3G78N@35493|Streptophyta,3M3P5@4447|Liliopsida,3IGBJ@38820|Poales	35493|Streptophyta	S	Protein TRANSPARENT TESTA	-	GO:0000003,GO:0000902,GO:0000904,GO:0001709,GO:0003006,GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009653,GO:0009791,GO:0009812,GO:0009813,GO:0009826,GO:0009856,GO:0009860,GO:0009889,GO:0009908,GO:0009932,GO:0009987,GO:0010154,GO:0010468,GO:0010500,GO:0010556,GO:0016043,GO:0016049,GO:0019219,GO:0019222,GO:0022414,GO:0030154,GO:0031323,GO:0031326,GO:0032501,GO:0032502,GO:0032989,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0044706,GO:0045165,GO:0048367,GO:0048438,GO:0048467,GO:0048468,GO:0048588,GO:0048589,GO:0048608,GO:0048731,GO:0048856,GO:0048868,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051704,GO:0060255,GO:0060560,GO:0061458,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090567,GO:0140110,GO:1901576,GO:1903506,GO:1990058,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-C2H2
MMS3_k127_108463_0	1267535.KB906767_gene1634	1.639e-150	495.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene1634|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_108463_1	639030.JHVA01000001_gene101	4.685e-20	105.0	COG0457@1|root,COG0457@2|Bacteria,3Y4E6@57723|Acidobacteria,2JKG2@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2
MMS3_k127_1090399_6	1267535.KB906767_gene630	1.835e-104	344.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria,2JHYU@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_1090399_5	452637.Oter_1900	7.785e-111	362.0	COG1136@1|root,COG1136@2|Bacteria,46TVQ@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1090399_0	1267533.KB906736_gene1071	3.006e-263	836.0	COG0577@1|root,COG0577@2|Bacteria,3Y6B8@57723|Acidobacteria,2JK7N@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1090399_7	234267.Acid_5354	7.056e-91	315.0	COG2204@1|root,COG2208@1|root,COG2204@2|Bacteria,COG2208@2|Bacteria,3Y49J@57723|Acidobacteria	57723|Acidobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
MMS3_k127_1090399_3	1183438.GKIL_2517	3.429e-131	430.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMS3_k127_1090399_8	278963.ATWD01000002_gene371	2.503e-80	291.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NZ@57723|Acidobacteria,2JI75@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_1090399_4	234267.Acid_5935	3.354e-125	419.0	COG1414@1|root,COG1879@1|root,COG1414@2|Bacteria,COG1879@2|Bacteria,3Y3RJ@57723|Acidobacteria	57723|Acidobacteria	K	IclR helix-turn-helix domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	HTH_IclR,Peripla_BP_4
MMS3_k127_1090399_2	234267.Acid_5958	2.108e-178	566.0	COG4952@1|root,COG4952@2|Bacteria,3Y3J5@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Xylose isomerase	-	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
MMS3_k127_1090399_1	682795.AciX8_1115	1.534e-253	796.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,3Y3GI@57723|Acidobacteria,2JIKQ@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Rhamnulose-1-phosphate aldolase alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
MMS3_k127_1092075_3	1172188.KB911820_gene2672	3.008e-45	167.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4FHED@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
MMS3_k127_1092075_1	234267.Acid_2381	2.343e-163	519.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.303	ko:K20421	ko01059,ko01130,map01059,map01130	M00830	R10963	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25
MMS3_k127_1092075_0	1267534.KB906756_gene343	1.957e-188	599.0	COG0412@1|root,COG0412@2|Bacteria,3Y2PZ@57723|Acidobacteria,2JKJA@204432|Acidobacteriia	204432|Acidobacteriia	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1092075_2	234267.Acid_0953	1.881e-73	255.0	COG0639@1|root,COG0639@2|Bacteria,3Y3U2@57723|Acidobacteria	57723|Acidobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_1092075_5	1267535.KB906767_gene4974	1.374e-16	85.0	2DNWY@1|root,32UJU@2|Bacteria,3Y584@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
MMS3_k127_1092075_4	278963.ATWD01000001_gene3596	4.001e-43	159.0	COG0312@1|root,COG0312@2|Bacteria,3Y39N@57723|Acidobacteria,2JIHC@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMS3_k127_1094171_0	240015.ACP_1416	1.067e-53	205.0	COG1538@1|root,COG1538@2|Bacteria,3Y5F3@57723|Acidobacteria,2JK84@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_1094171_1	1379698.RBG1_1C00001G0563	3.118e-29	121.0	COG0640@1|root,COG0640@2|Bacteria,2NQ74@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
MMS3_k127_1094171_2	391625.PPSIR1_32477	9.939e-09	64.0	COG0515@1|root,COG0515@2|Bacteria	391625.PPSIR1_32477|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1094417_0	1283300.ATXB01000001_gene875	9.893e-94	312.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1XEMR@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
MMS3_k127_1094417_1	1120973.AQXL01000133_gene1794	2.309e-86	291.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli,27907@186823|Alicyclobacillaceae	91061|Bacilli	E	Aconitase C-terminal domain	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
MMS3_k127_1094417_2	1267535.KB906767_gene394	1.395e-33	136.0	COG0705@1|root,COG0705@2|Bacteria,3Y4GU@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
MMS3_k127_110003_1	204669.Acid345_3439	2.149e-93	317.0	COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
MMS3_k127_110003_2	391623.TERMP_01541	2.382e-61	220.0	COG0274@1|root,arCOG04320@2157|Archaea,2XT2D@28890|Euryarchaeota,242NJ@183968|Thermococci	183968|Thermococci	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
MMS3_k127_110003_5	1047013.AQSP01000012_gene262	8.665e-22	100.0	COG3824@1|root,COG3824@2|Bacteria,2NPZF@2323|unclassified Bacteria	2|Bacteria	S	Zincin-like metallopeptidase	MA20_43655	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Zincin_1
MMS3_k127_110003_6	1423734.JCM14202_1819	4.172e-18	93.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,3F3WV@33958|Lactobacillaceae	91061|Bacilli	O	Universal bacterial protein YeaZ	yeaZ	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
MMS3_k127_110003_4	633697.EubceDRAFT1_1748	3.135e-22	103.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,25XAS@186806|Eubacteriaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
MMS3_k127_110003_3	401053.AciPR4_3654	5.136e-43	160.0	COG1695@1|root,COG1695@2|Bacteria,3Y7Y6@57723|Acidobacteria,2JMXG@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_110003_0	234267.Acid_6252	4.026e-196	638.0	COG0577@1|root,COG0577@2|Bacteria,3Y6YF@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1100387_1	1267535.KB906767_gene2363	3.428e-167	536.0	COG3345@1|root,COG3345@2|Bacteria,3Y3GU@57723|Acidobacteria,2JP5Z@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
MMS3_k127_1100387_4	240015.ACP_2463	4.53e-35	147.0	COG1266@1|root,COG1266@2|Bacteria,3Y4ED@57723|Acidobacteria,2JJ3Q@204432|Acidobacteriia	204432|Acidobacteriia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_1100387_3	234267.Acid_7366	1.103e-42	168.0	2D61V@1|root,32TKB@2|Bacteria,3Y5CF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1100387_0	1267535.KB906767_gene4535	1.554e-195	617.0	COG4941@1|root,COG4941@2|Bacteria,3Y6IY@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1100387_2	1267535.KB906767_gene4533	1.555e-52	188.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMS3_k127_1111048_0	1234364.AMSF01000025_gene3675	5.411e-145	481.0	arCOG05967@1|root,2Z8PR@2|Bacteria,1QSXZ@1224|Proteobacteria,1RWJW@1236|Gammaproteobacteria,1X3YX@135614|Xanthomonadales	135614|Xanthomonadales	S	Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A	-	-	-	-	-	-	-	-	-	-	-	-	PNGaseA
MMS3_k127_1111048_1	319225.Plut_0105	2.314e-42	162.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
MMS3_k127_1111405_2	1267535.KB906767_gene889	9.307e-24	102.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	ermC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
MMS3_k127_1111405_0	1267533.KB906737_gene1500	1.358e-259	813.0	2DUQS@1|root,33RT2@2|Bacteria,3Y6EQ@57723|Acidobacteria,2JMHN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1111405_1	234267.Acid_0089	7.144e-90	312.0	COG2755@1|root,COG2755@2|Bacteria,3Y61E@57723|Acidobacteria	57723|Acidobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMS3_k127_1118879_18	1267535.KB906767_gene2452	2.466e-39	150.0	COG4948@1|root,COG4948@2|Bacteria,3Y6CG@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_1118879_19	1101191.KI912577_gene3851	4.298e-33	142.0	COG0451@1|root,COG0451@2|Bacteria,1MVGI@1224|Proteobacteria,2VFSD@28211|Alphaproteobacteria,1JTN1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
MMS3_k127_1118879_6	234267.Acid_1065	1.376e-186	586.0	COG2876@1|root,COG2876@2|Bacteria,3Y64W@57723|Acidobacteria	57723|Acidobacteria	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
MMS3_k127_1118879_3	234267.Acid_5781	1.351e-204	649.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_1118879_11	502025.Hoch_4295	3.361e-119	392.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YYA3@29|Myxococcales	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_1118879_5	1267535.KB906767_gene2792	7.268e-190	597.0	COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria,2JIQ4@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1118879_4	1267535.KB906767_gene2791	1.566e-194	613.0	COG0156@1|root,COG0156@2|Bacteria,3Y3J2@57723|Acidobacteria,2JI0H@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_1118879_14	1267535.KB906767_gene1126	3.156e-104	347.0	COG0709@1|root,COG0709@2|Bacteria,3Y6V3@57723|Acidobacteria	57723|Acidobacteria	E	AIR synthase related protein, C-terminal domain	-	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
MMS3_k127_1118879_15	326427.Cagg_0266	4.472e-102	345.0	COG1364@1|root,COG1364@2|Bacteria,2G64K@200795|Chloroflexi,37529@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	-	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
MMS3_k127_1118879_17	219305.MCAG_00296	4.413e-76	274.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
MMS3_k127_1118879_8	278963.ATWD01000002_gene751	7.551e-166	537.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
MMS3_k127_1118879_2	1382359.JIAL01000001_gene1544	9.167e-262	820.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
MMS3_k127_1118879_10	1198114.AciX9_1936	1.449e-163	546.0	COG2091@1|root,COG2091@2|Bacteria,3Y46J@57723|Acidobacteria,2JHWP@204432|Acidobacteriia	204432|Acidobacteriia	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1118879_13	234267.Acid_1085	1.464e-111	369.0	COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
MMS3_k127_1118879_16	204669.Acid345_0159	3.629e-98	332.0	COG1606@1|root,COG1606@2|Bacteria,3Y30C@57723|Acidobacteria,2JKD3@204432|Acidobacteriia	204432|Acidobacteriia	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
MMS3_k127_1118879_0	234267.Acid_3975	0.0	1058.0	COG0188@1|root,COG0188@2|Bacteria,3Y2G5@57723|Acidobacteria	57723|Acidobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMS3_k127_1118879_1	880072.Desac_0486	3.512e-273	861.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MQ5F@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMS3_k127_1118879_12	234267.Acid_0002	5.917e-114	378.0	COG0592@1|root,COG0592@2|Bacteria,3Y2WE@57723|Acidobacteria	57723|Acidobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
MMS3_k127_1118879_9	204669.Acid345_0001	1.123e-164	529.0	COG0593@1|root,COG0593@2|Bacteria,3Y2HA@57723|Acidobacteria,2JHN7@204432|Acidobacteriia	204432|Acidobacteriia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
MMS3_k127_1118879_20	937777.Deipe_3527	9.983e-22	110.0	COG2512@1|root,COG2865@1|root,COG2512@2|Bacteria,COG2865@2|Bacteria,1WIVH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	transcriptional regulator	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
MMS3_k127_1118879_7	1267533.KB906733_gene3362	1.496e-171	559.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
MMS3_k127_1119304_1	1379698.RBG1_1C00001G0140	3.206e-17	83.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD,Excalibur
MMS3_k127_1119304_0	1382359.JIAL01000001_gene703	2.655e-143	464.0	COG3408@1|root,COG3408@2|Bacteria,3Y7ET@57723|Acidobacteria,2JNVJ@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C
MMS3_k127_1120799_2	682795.AciX8_4387	5.642e-102	348.0	COG1538@1|root,COG1538@2|Bacteria,3Y54R@57723|Acidobacteria,2JM71@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_1120799_1	240015.ACP_1203	2.277e-178	573.0	COG0845@1|root,COG0845@2|Bacteria,3Y49U@57723|Acidobacteria,2JM3N@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,YtkA
MMS3_k127_1120799_0	682795.AciX8_4389	0.0	1259.0	COG3696@1|root,COG3696@2|Bacteria,3Y3AQ@57723|Acidobacteria,2JKZY@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
MMS3_k127_1122625_4	1267535.KB906767_gene4177	8.219e-08	62.0	COG2885@1|root,COG2885@2|Bacteria,3Y310@57723|Acidobacteria	57723|Acidobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMS3_k127_1122625_2	1123368.AUIS01000004_gene128	1.119e-39	160.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,1RP8E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
MMS3_k127_1122625_3	240015.ACP_0904	9.824e-30	125.0	COG0797@1|root,COG0797@2|Bacteria,3Y58C@57723|Acidobacteria,2JJUS@204432|Acidobacteriia	204432|Acidobacteriia	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
MMS3_k127_1122625_1	234267.Acid_4469	8.059e-74	254.0	COG2227@1|root,COG2227@2|Bacteria,3Y2SJ@57723|Acidobacteria	57723|Acidobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_1122625_0	204669.Acid345_0176	4.402e-104	351.0	COG0535@1|root,COG0535@2|Bacteria,3Y3TY@57723|Acidobacteria,2JHZQ@204432|Acidobacteriia	204432|Acidobacteriia	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
MMS3_k127_1122956_2	234267.Acid_3524	1.85e-113	374.0	COG4948@1|root,COG4948@2|Bacteria,3Y403@57723|Acidobacteria	57723|Acidobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_1122956_1	390989.JOEG01000002_gene4164	1.808e-132	433.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4D8TB@85008|Micromonosporales	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_1122956_0	620914.JH621250_gene2310	3.985e-167	539.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1I031@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS3_k127_1122956_3	1123508.JH636441_gene3316	3.644e-21	108.0	2E1DD@1|root,32WSP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_112397_1	227377.CBU_1928	6.966e-140	460.0	COG0204@1|root,COG0236@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1JCGB@118969|Legionellales	118969|Legionellales	IQ	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
MMS3_k127_112397_2	502025.Hoch_3248	4.908e-87	307.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
MMS3_k127_112397_3	1267535.KB906767_gene3789	3.113e-66	232.0	COG0558@1|root,COG0558@2|Bacteria,3Y427@57723|Acidobacteria,2JID7@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_112397_0	471223.GWCH70_1487	1.824e-144	472.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1WE4Y@129337|Geobacillus	91061|Bacilli	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
MMS3_k127_1125941_1	649638.Trad_0147	4.685e-273	851.0	COG1048@1|root,COG1048@2|Bacteria,1WIMG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acn	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMS3_k127_1125941_2	1123023.JIAI01000032_gene4146	1.559e-32	135.0	29J5I@1|root,3062Y@2|Bacteria,2I9N8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1125941_0	215803.DB30_4199	0.0	1112.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria,2YWJW@29|Myxococcales	28221|Deltaproteobacteria	P	Cytochrome C and Quinol oxidase polypeptide I	norZ	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
MMS3_k127_1125941_4	797302.Halru_0571	0.0001377	52.0	COG1506@1|root,arCOG03383@1|root,arCOG01646@2157|Archaea,arCOG03383@2157|Archaea,2XVEA@28890|Euryarchaeota,23SDU@183963|Halobacteria	183963|Halobacteria	E	Peptidase S9 prolyl oligopeptidase active site	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
MMS3_k127_1125941_3	756272.Plabr_2578	1.979e-10	62.0	COG0388@1|root,COG0388@2|Bacteria,2IXKW@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
MMS3_k127_1130849_2	479435.Kfla_1477	4.011e-09	59.0	COG1028@1|root,COG1028@2|Bacteria,2IBUE@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1130849_0	1499967.BAYZ01000136_gene45	9.142e-223	708.0	COG1154@1|root,COG1154@2|Bacteria,2NNNA@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527	DXP_synthase_N,Transket_pyr,Transketolase_C
MMS3_k127_1130849_1	1267535.KB906767_gene4165	3.251e-88	299.0	COG0142@1|root,COG0142@2|Bacteria,3Y2HS@57723|Acidobacteria,2JIPK@204432|Acidobacteriia	204432|Acidobacteriia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS3_k127_113859_5	1267534.KB906757_gene1034	1.77e-26	119.0	COG0526@1|root,COG0526@2|Bacteria,3Y4MM@57723|Acidobacteria,2JJCE@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMS3_k127_113859_2	204669.Acid345_1901	1.068e-71	247.0	COG0491@1|root,COG0491@2|Bacteria,3Y4DN@57723|Acidobacteria,2JJ36@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_113859_3	84531.JMTZ01000009_gene3330	2.286e-60	221.0	COG0500@1|root,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,1T2EV@1236|Gammaproteobacteria,1XD5B@135614|Xanthomonadales	135614|Xanthomonadales	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
MMS3_k127_113859_4	204669.Acid345_0669	8.902e-52	190.0	COG1335@1|root,COG1335@2|Bacteria,3Y5W2@57723|Acidobacteria	57723|Acidobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
MMS3_k127_113859_0	1267533.KB906741_gene553	6.13e-322	1010.0	COG4354@1|root,COG4354@2|Bacteria,3Y2ZY@57723|Acidobacteria,2JHZE@204432|Acidobacteriia	204432|Acidobacteriia	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
MMS3_k127_113859_1	1267535.KB906767_gene820	2.244e-131	424.0	COG0214@1|root,COG0214@2|Bacteria,3Y3ST@57723|Acidobacteria,2JKN5@204432|Acidobacteriia	204432|Acidobacteriia	H	Belongs to the PdxS SNZ family	-	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
MMS3_k127_1139353_4	234267.Acid_1278	1.982e-16	81.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria	57723|Acidobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMS3_k127_1139353_3	1499967.BAYZ01000074_gene2162	2.128e-19	93.0	COG1862@1|root,COG1862@2|Bacteria,2NPY3@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase, YajC	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
MMS3_k127_1139353_1	273068.TTE1183	1.32e-133	436.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,42EMN@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
MMS3_k127_1139353_2	234267.Acid_1121	9.448e-34	140.0	2BRBT@1|root,32KAC@2|Bacteria,3Y4U0@57723|Acidobacteria	57723|Acidobacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
MMS3_k127_1139353_0	204669.Acid345_4296	8.736e-137	437.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_1140415_1	1267535.KB906767_gene984	1.001e-29	121.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
MMS3_k127_1140415_0	204669.Acid345_1196	0.0	1049.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y2P5@57723|Acidobacteria,2JMA3@204432|Acidobacteriia	204432|Acidobacteriia	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS3_k127_11475_2	234267.Acid_4486	6.529e-211	668.0	COG0595@1|root,COG0595@2|Bacteria,3Y2NH@57723|Acidobacteria	57723|Acidobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
MMS3_k127_11475_0	204669.Acid345_1757	5.949e-230	737.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria,2JHRN@204432|Acidobacteriia	204432|Acidobacteriia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
MMS3_k127_11475_1	344747.PM8797T_16213	5.169e-217	683.0	COG2217@1|root,COG2217@2|Bacteria,2IXE1@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
MMS3_k127_1155178_6	555079.Toce_0137	7.597e-53	190.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
MMS3_k127_1155178_14	553175.POREN0001_0220	8.272e-08	60.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,2FUJQ@200643|Bacteroidia	976|Bacteroidetes	J	50S ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
MMS3_k127_1155178_3	1120971.AUCA01000013_gene2622	4.194e-62	217.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,278WX@186823|Alicyclobacillaceae	91061|Bacilli	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
MMS3_k127_1155178_10	246194.CHY_2293	2.804e-37	144.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,42GIE@68295|Thermoanaerobacterales	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
MMS3_k127_1155178_5	1267535.KB906767_gene2690	1.354e-56	203.0	COG0097@1|root,COG0097@2|Bacteria,3Y496@57723|Acidobacteria	57723|Acidobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
MMS3_k127_1155178_7	1340493.JNIF01000003_gene3221	2.905e-51	184.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
MMS3_k127_1155178_13	1379698.RBG1_1C00001G1583	5.33e-23	98.0	COG0199@1|root,COG0199@2|Bacteria,2NPW7@2323|unclassified Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
MMS3_k127_1155178_1	234267.Acid_5106	6.212e-79	270.0	COG0094@1|root,COG0094@2|Bacteria,3Y3PS@57723|Acidobacteria	57723|Acidobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
MMS3_k127_1155178_11	240015.ACP_1440	1.333e-32	131.0	COG0198@1|root,COG0198@2|Bacteria,3Y56T@57723|Acidobacteria,2JJQ2@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
MMS3_k127_1155178_4	1267535.KB906767_gene2694	4.495e-58	205.0	COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria,2JJ86@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
MMS3_k127_1155178_12	648996.Theam_0266	1.099e-25	108.0	COG0186@1|root,COG0186@2|Bacteria,2G49I@200783|Aquificae	200783|Aquificae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
MMS3_k127_1155178_15	345341.KUTG_05858	1.608e-05	50.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4E5RB@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
MMS3_k127_1155178_2	204669.Acid345_1233	1.166e-67	231.0	COG0197@1|root,COG0197@2|Bacteria,3Y4EG@57723|Acidobacteria,2JJ2G@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
MMS3_k127_1155178_0	880072.Desac_1450	1.115e-85	289.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,2MQ8I@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
MMS3_k127_1155178_9	234267.Acid_5113	1.051e-39	151.0	COG0091@1|root,COG0091@2|Bacteria,3Y4KH@57723|Acidobacteria	57723|Acidobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
MMS3_k127_1155178_8	234267.Acid_5114	3.688e-40	151.0	COG0185@1|root,COG0185@2|Bacteria,3Y560@57723|Acidobacteria	57723|Acidobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
MMS3_k127_1156053_6	1121439.dsat_1282	3.167e-75	284.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,439Z2@68525|delta/epsilon subdivisions,2X1YW@28221|Deltaproteobacteria,2M834@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1156053_10	1121439.dsat_1281	5.235e-54	217.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2WPW2@28221|Deltaproteobacteria,2MG3X@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1156053_11	1307759.JOMJ01000004_gene2492	2.466e-51	198.0	COG1215@1|root,COG1215@2|Bacteria,1PU38@1224|Proteobacteria,42UXK@68525|delta/epsilon subdivisions,2WQNC@28221|Deltaproteobacteria,2MAIF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
MMS3_k127_1156053_15	883.DvMF_0679	1.408e-17	96.0	COG3307@1|root,COG3307@2|Bacteria,1NGAP@1224|Proteobacteria,42XF9@68525|delta/epsilon subdivisions,2X5BY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_1156053_16	1123073.KB899243_gene608	4.702e-09	67.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1X4AM@135614|Xanthomonadales	135614|Xanthomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
MMS3_k127_1156053_7	1234364.AMSF01000010_gene547	3.538e-65	241.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1X5B9@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C_2
MMS3_k127_1156053_3	1121439.dsat_1279	1.618e-86	303.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria,2MATU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
MMS3_k127_1156053_4	525897.Dbac_2217	6.02e-84	289.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,42P7W@68525|delta/epsilon subdivisions,2WMHU@28221|Deltaproteobacteria,2M9ER@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
MMS3_k127_1156053_0	401053.AciPR4_0582	2.836e-122	406.0	COG2148@1|root,COG2148@2|Bacteria,3Y4JY@57723|Acidobacteria,2JJ8R@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
MMS3_k127_1156053_9	1382359.JIAL01000001_gene941	1.591e-56	209.0	COG0489@1|root,COG0489@2|Bacteria,3Y59M@57723|Acidobacteria,2JJS6@204432|Acidobacteriia	204432|Acidobacteriia	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
MMS3_k127_1156053_2	639030.JHVA01000001_gene3247	1.743e-87	300.0	COG3267@1|root,COG3267@2|Bacteria,3Y6P4@57723|Acidobacteria,2JKNX@204432|Acidobacteriia	204432|Acidobacteriia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
MMS3_k127_1156053_1	1267534.KB906757_gene891	3.531e-97	337.0	COG3206@1|root,COG3206@2|Bacteria,3Y3JI@57723|Acidobacteria,2JI13@204432|Acidobacteriia	204432|Acidobacteriia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
MMS3_k127_1156053_14	1382359.JIAL01000001_gene944	5.272e-36	154.0	2EF70@1|root,33901@2|Bacteria,3Y5Q5@57723|Acidobacteria,2JJZV@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1156053_8	1382359.JIAL01000001_gene945	1.026e-57	207.0	COG1596@1|root,COG1596@2|Bacteria,3Y51C@57723|Acidobacteria,2JJMM@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
MMS3_k127_1156053_12	215803.DB30_1938	1.396e-48	186.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,439C6@68525|delta/epsilon subdivisions,2X4KA@28221|Deltaproteobacteria,2YZ6R@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_1156053_5	1267534.KB906757_gene894	6.198e-76	265.0	COG1269@1|root,COG1269@2|Bacteria,3Y7E1@57723|Acidobacteria,2JKI6@204432|Acidobacteriia	204432|Acidobacteriia	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
MMS3_k127_1156053_13	278963.ATWD01000001_gene2192	3.074e-48	180.0	COG1269@1|root,COG1269@2|Bacteria,3Y565@57723|Acidobacteria,2JMUB@204432|Acidobacteriia	204432|Acidobacteriia	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
MMS3_k127_1156053_18	234267.Acid_3324	1.824e-06	53.0	COG0457@1|root,COG0457@2|Bacteria,3Y7CG@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMS3_k127_1160482_1	357808.RoseRS_1236	6.953e-93	315.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,376BU@32061|Chloroflexia	2|Bacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1160482_2	383372.Rcas_3764	9.048e-56	205.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_1160482_0	1382359.JIAL01000001_gene442	1.688e-262	818.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060,Glyco_hydro_115
MMS3_k127_1175811_0	671143.DAMO_1938	2.446e-143	461.0	COG0731@1|root,COG0731@2|Bacteria,2NPIJ@2323|unclassified Bacteria	2|Bacteria	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
MMS3_k127_1175811_1	290397.Adeh_1894	2.499e-19	91.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,42XUW@68525|delta/epsilon subdivisions,2WSV8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
MMS3_k127_1175855_1	204669.Acid345_1460	2.405e-41	160.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FecR,LysM,fn3
MMS3_k127_1175855_0	240015.ACP_1060	1.38e-81	295.0	COG0760@1|root,COG0760@2|Bacteria,3Y3BW@57723|Acidobacteria,2JIP1@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
MMS3_k127_1175855_3	293826.Amet_3687	2.179e-19	93.0	COG2128@1|root,COG2128@2|Bacteria,1VQME@1239|Firmicutes,24V56@186801|Clostridia	186801|Clostridia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_1175855_2	1382359.JIAL01000001_gene29	7.341e-24	103.0	COG2128@1|root,COG2128@2|Bacteria,3Y8IA@57723|Acidobacteria,2JNES@204432|Acidobacteriia	204432|Acidobacteriia	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_1175855_4	378806.STAUR_0766	5.704e-15	75.0	COG0667@1|root,COG0667@2|Bacteria,1R8HH@1224|Proteobacteria	1224|Proteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_1178055_3	497964.CfE428DRAFT_0868	2.716e-35	139.0	COG2808@1|root,COG2808@2|Bacteria	2|Bacteria	K	Putative FMN-binding domain	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
MMS3_k127_1178055_1	234267.Acid_7194	5.855e-79	271.0	COG0024@1|root,COG0024@2|Bacteria	2|Bacteria	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMS3_k127_1178055_4	573413.Spirs_2362	1.623e-24	121.0	COG0457@1|root,COG0457@2|Bacteria,2J5NB@203691|Spirochaetes	203691|Spirochaetes	S	tetratricopeptide repeat	lmp1	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
MMS3_k127_1178055_6	96561.Dole_2626	3.15e-09	70.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_2,TPR_7,TPR_8
MMS3_k127_1178055_5	452637.Oter_3198	1.775e-15	91.0	COG0457@1|root,COG0457@2|Bacteria,46V1N@74201|Verrucomicrobia,3KA0R@414999|Opitutae	74201|Verrucomicrobia	M	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_11,TPR_16,TPR_2,TPR_8
MMS3_k127_1178055_2	639030.JHVA01000001_gene2045	1.323e-60	211.0	COG1960@1|root,COG1960@2|Bacteria,3Y32R@57723|Acidobacteria,2JIRM@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1180951_8	330214.NIDE3354	5.986e-10	61.0	COG0005@1|root,COG0005@2|Bacteria,3J0HC@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_1180951_4	869210.Marky_1204	1.22e-75	262.0	COG0491@1|root,COG0491@2|Bacteria,1WISH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_1180951_7	342949.PNA2_0788	1.288e-38	150.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,24458@183968|Thermococci	183968|Thermococci	E	Glyoxalase-like domain	-	GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
MMS3_k127_1180951_2	204669.Acid345_2365	1.328e-94	320.0	COG1703@1|root,COG1703@2|Bacteria,3Y40X@57723|Acidobacteria,2JHW8@204432|Acidobacteriia	204432|Acidobacteriia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
MMS3_k127_1180951_0	1382359.JIAL01000001_gene2614	4.513e-164	524.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1180951_9	926566.Terro_2901	2.652e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,3Y2Q7@57723|Acidobacteria,2JIH1@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_11,TPR_16,TPR_2,TPR_8
MMS3_k127_1180951_1	204669.Acid345_2367	1.598e-138	449.0	COG2008@1|root,COG2008@2|Bacteria,3Y472@57723|Acidobacteria,2JIUS@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
MMS3_k127_1180951_3	204669.Acid345_2366	3.509e-87	302.0	COG0635@1|root,COG0635@2|Bacteria,3Y2ZB@57723|Acidobacteria,2JHUT@204432|Acidobacteriia	204432|Acidobacteriia	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
MMS3_k127_1180951_5	243274.THEMA_04810	3.251e-42	160.0	COG0432@1|root,COG0432@2|Bacteria,2GD2P@200918|Thermotogae	200918|Thermotogae	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
MMS3_k127_1180951_6	204669.Acid345_2181	5.928e-39	153.0	COG4365@1|root,COG4365@2|Bacteria,3Y4D6@57723|Acidobacteria,2JKER@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
MMS3_k127_1190617_3	1033806.HTIA_0901	3.019e-05	51.0	COG0477@1|root,arCOG00132@2157|Archaea,2Y8EM@28890|Euryarchaeota,2419S@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1190617_1	335541.Swol_1667	2.29e-33	140.0	COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,24DU6@186801|Clostridia,42KKD@68298|Syntrophomonadaceae	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
MMS3_k127_1190617_2	882.DVU_3344	2.561e-13	82.0	COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
MMS3_k127_1190617_4	1297742.A176_03201	0.0002572	51.0	2DN5Z@1|root,32VR7@2|Bacteria,1RI34@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
MMS3_k127_1190617_0	1382359.JIAL01000001_gene86	1.118e-46	171.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1193339_8	204669.Acid345_3851	1.865e-30	131.0	COG5662@1|root,COG5662@2|Bacteria,3Y4JS@57723|Acidobacteria,2JJ7U@204432|Acidobacteriia	204432|Acidobacteriia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMS3_k127_1193339_5	1267533.KB906733_gene3238	3.485e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria,2JJ89@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1193339_9	937777.Deipe_0695	5.189e-20	91.0	COG0695@1|root,COG0695@2|Bacteria,1WKDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	PFAM glutaredoxin	grxA	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
MMS3_k127_1193339_7	204669.Acid345_4331	1.463e-31	128.0	COG0355@1|root,COG0355@2|Bacteria,3Y515@57723|Acidobacteria,2JJJV@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
MMS3_k127_1193339_0	204669.Acid345_4332	6.205e-246	767.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
MMS3_k127_1193339_4	671143.DAMO_2963	5.548e-83	284.0	COG0224@1|root,COG0224@2|Bacteria,2NP76@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
MMS3_k127_1193339_1	234267.Acid_0463	2.952e-245	766.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
MMS3_k127_1193339_6	1382359.JIAL01000001_gene2066	2.728e-38	149.0	COG0712@1|root,COG0712@2|Bacteria,3Y4Z4@57723|Acidobacteria,2JJM8@204432|Acidobacteriia	204432|Acidobacteriia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
MMS3_k127_1193339_11	234267.Acid_0461	1.239e-08	64.0	COG0711@1|root,COG0711@2|Bacteria,3Y4UJ@57723|Acidobacteria	57723|Acidobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
MMS3_k127_1193339_10	234267.Acid_0460	1.178e-10	68.0	COG0711@1|root,COG0711@2|Bacteria,3Y4WK@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the ATPase B chain family	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
MMS3_k127_1193339_3	313624.NSP_14580	8.184e-103	350.0	COG0277@1|root,COG0277@2|Bacteria,1G6C2@1117|Cyanobacteria,1HIC7@1161|Nostocales	1117|Cyanobacteria	C	FAD binding domain	-	-	1.1.3.8,1.5.99.12	ko:K00103,ko:K00279	ko00053,ko00908,ko01100,map00053,map00908,map01100	M00129	R00647,R03184,R05708,R10053	RC00121,RC00195,RC00346,RC00869,RC01455	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,Cytokin-bind,FAD_binding_4
MMS3_k127_1193339_2	639030.JHVA01000001_gene2436	2.122e-144	469.0	COG1249@1|root,COG1249@2|Bacteria,3Y2M8@57723|Acidobacteria,2JIAI@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_1193961_3	240015.ACP_1387	1.287e-15	77.0	COG0493@1|root,COG0493@2|Bacteria,3Y3EA@57723|Acidobacteria,2JJCC@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	M00046	R00093,R00114,R00248,R00977,R01414,R10159,R11026	RC00006,RC00010,RC00072,RC00123,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
MMS3_k127_1193961_0	278963.ATWD01000001_gene2921	1.512e-297	949.0	COG0383@1|root,COG0383@2|Bacteria,3Y3ID@57723|Acidobacteria,2JINT@204432|Acidobacteriia	2|Bacteria	G	Glycosyl hydrolase 38 domain protein	ams1	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
MMS3_k127_1193961_2	402777.KB235898_gene5013	1.232e-39	159.0	COG2971@1|root,COG2971@2|Bacteria,1G3SA@1117|Cyanobacteria,1H9RT@1150|Oscillatoriales	1117|Cyanobacteria	G	BadF BadG BcrA BcrD	-	-	2.7.1.59	ko:K00884,ko:K02616	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000,ko03000	-	-	-	BcrAD_BadFG
MMS3_k127_1193961_1	234267.Acid_7026	2.926e-165	543.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y7F9@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1213440_4	1499967.BAYZ01000154_gene1466	1.085e-57	220.0	COG0699@1|root,COG0699@2|Bacteria	2|Bacteria	T	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
MMS3_k127_1213440_2	1033732.CAHI01000007_gene2094	9.947e-208	672.0	COG2010@1|root,COG3533@1|root,COG2010@2|Bacteria,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes	976|Bacteroidetes	C	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Big_4,DUF4986,Glyco_hydro_127,Laminin_G_3
MMS3_k127_1213440_1	1382359.JIAL01000001_gene618	6.498e-212	687.0	COG2844@1|root,COG2844@2|Bacteria,3Y2FJ@57723|Acidobacteria,2JI19@204432|Acidobacteriia	204432|Acidobacteriia	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
MMS3_k127_1213440_3	1121396.KB892950_gene2992	6.484e-85	290.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WMXZ@28221|Deltaproteobacteria,2MJS0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
MMS3_k127_1213440_0	886293.Sinac_7544	1.18e-215	705.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2J4YH@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
MMS3_k127_1241491_8	234267.Acid_5841	1.254e-29	120.0	COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
MMS3_k127_1241491_6	204669.Acid345_0137	6.516e-51	188.0	COG3468@1|root,COG3468@2|Bacteria,3Y4NE@57723|Acidobacteria,2JJBC@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1241491_2	204669.Acid345_0136	3.127e-95	318.0	COG1521@1|root,COG1521@2|Bacteria,3Y398@57723|Acidobacteria,2JI76@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
MMS3_k127_1241491_4	204669.Acid345_0135	5.416e-82	284.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,3Y4PB@57723|Acidobacteria,2JJAU@204432|Acidobacteriia	204432|Acidobacteriia	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
MMS3_k127_1241491_3	1089553.Tph_c26610	4.995e-85	291.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,42F8G@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
MMS3_k127_1241491_0	204669.Acid345_0132	1.254e-296	937.0	COG0525@1|root,COG0525@2|Bacteria,3Y2JY@57723|Acidobacteria,2JIBS@204432|Acidobacteriia	204432|Acidobacteriia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
MMS3_k127_1241491_5	234267.Acid_3192	2.634e-60	226.0	COG4105@1|root,COG4105@2|Bacteria,3Y36S@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6,YfiO
MMS3_k127_1241491_7	1185653.A1A1_03887	3.09e-44	169.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26DNF@186818|Planococcaceae	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
MMS3_k127_1241491_10	1173027.Mic7113_5925	6.684e-11	71.0	COG2204@1|root,COG2204@2|Bacteria,1G623@1117|Cyanobacteria,1HFTT@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_8
MMS3_k127_1241491_1	391625.PPSIR1_15000	3.25e-105	349.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2WQU9@28221|Deltaproteobacteria,2YXHW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
MMS3_k127_1260214_1	1238182.C882_0987	1.987e-107	367.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,2JREK@204441|Rhodospirillales	204441|Rhodospirillales	G	Maltogenic Amylase, C-terminal domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
MMS3_k127_1260214_2	1267535.KB906767_gene1717	4.651e-63	229.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y8N8@57723|Acidobacteria,2JNIX@204432|Acidobacteriia	1267535.KB906767_gene1717|-	EG	L-rhamnose-proton symport protein (RhaT)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1260214_0	1267535.KB906767_gene1452	4.001e-173	549.0	COG1501@1|root,COG1501@2|Bacteria,3Y35Y@57723|Acidobacteria,2JI95@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, clan GH-D	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
MMS3_k127_1272481_2	1267535.KB906767_gene3317	2.201e-166	547.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_1272481_1	1267534.KB906759_gene1742	6.864e-182	580.0	COG1457@1|root,COG1457@2|Bacteria,3Y6MB@57723|Acidobacteria,2JKYN@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	ko:K10974	-	-	-	-	ko00000,ko02000	2.A.39.1	-	-	Transp_cyt_pur
MMS3_k127_1272481_7	1267535.KB906767_gene4335	2.35e-20	100.0	2F1JK@1|root,33UK0@2|Bacteria,3Y7KY@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1272481_0	1232410.KI421413_gene539	9.272e-184	587.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43RZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Glutamine amidotransferases class-II	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
MMS3_k127_1272481_6	1267535.KB906767_gene3062	6.089e-56	205.0	COG0681@1|root,COG0681@2|Bacteria,3Y40D@57723|Acidobacteria,2JHWM@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
MMS3_k127_1272481_3	240015.ACP_1372	9.696e-107	358.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_1272481_4	234267.Acid_6723	9.683e-76	258.0	COG0299@1|root,COG0299@2|Bacteria,3Y49G@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
MMS3_k127_1272481_5	1340493.JNIF01000003_gene1786	2.047e-58	205.0	COG0162@1|root,COG0162@2|Bacteria,3Y2NC@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
MMS3_k127_1273639_3	204669.Acid345_0476	2.149e-100	344.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,3Y2NX@57723|Acidobacteria	57723|Acidobacteria	O	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
MMS3_k127_1273639_4	204669.Acid345_0468	1.89e-76	268.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
MMS3_k127_1273639_0	204669.Acid345_0471	5.076e-182	582.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1273639_2	204669.Acid345_0472	5.668e-145	467.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
MMS3_k127_1276967_3	204669.Acid345_1477	3.116e-99	332.0	COG0583@1|root,COG0583@2|Bacteria,3Y4EH@57723|Acidobacteria,2JJ60@204432|Acidobacteriia	204432|Acidobacteriia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_1276967_2	926550.CLDAP_10210	3.506e-125	416.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the aspartokinase family	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
MMS3_k127_1276967_1	204669.Acid345_1480	1.94e-126	420.0	COG0498@1|root,COG0498@2|Bacteria,3Y3G4@57723|Acidobacteria,2JINC@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_1276967_0	1120973.AQXL01000134_gene1536	8.363e-175	580.0	COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli,278RF@186823|Alicyclobacillaceae	91061|Bacilli	C	Phosphoenolpyruvate carboxylase	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
MMS3_k127_1276967_4	204669.Acid345_1478	1.967e-85	293.0	COG0345@1|root,COG0345@2|Bacteria,3Y41B@57723|Acidobacteria,2JITZ@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
MMS3_k127_1276967_5	264732.Moth_1350	2.394e-59	208.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,42EVA@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
MMS3_k127_1277864_0	682795.AciX8_1908	2.996e-111	375.0	COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria,2JI79@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
MMS3_k127_1277864_2	1267535.KB906767_gene5329	2.545e-55	205.0	COG1940@1|root,COG1940@2|Bacteria,3Y62I@57723|Acidobacteria	57723|Acidobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMS3_k127_1277864_1	1121430.JMLG01000009_gene430	2.81e-72	252.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,2616Z@186807|Peptococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
MMS3_k127_1284932_0	1166018.FAES_5143	4.181e-71	253.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1284932_1	1237149.C900_04940	2.761e-67	245.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1285144_2	518766.Rmar_1923	8.411e-77	273.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1FISB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
MMS3_k127_1285144_3	234267.Acid_3369	1.463e-42	173.0	2E93F@1|root,333CD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1285144_0	1340493.JNIF01000004_gene816	7.708e-214	675.0	COG0043@1|root,COG0043@2|Bacteria,3Y3BY@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
MMS3_k127_1285144_1	1121378.KB899728_gene4132	9.098e-95	315.0	COG1249@1|root,COG1249@2|Bacteria,1WI3A@1297|Deinococcus-Thermus	2|Bacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	sthA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_1290_2	234267.Acid_6173	3.792e-63	218.0	COG1741@1|root,COG1741@2|Bacteria,3Y367@57723|Acidobacteria	57723|Acidobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMS3_k127_1290_1	1173023.KE650771_gene1232	1.418e-77	267.0	COG2227@1|root,COG2227@2|Bacteria,1G3TD@1117|Cyanobacteria,1JJVY@1189|Stigonemataceae	1117|Cyanobacteria	H	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_1290_0	639030.JHVA01000001_gene2827	1.068e-132	437.0	COG0405@1|root,COG0405@2|Bacteria,3Y2N0@57723|Acidobacteria,2JHK2@204432|Acidobacteriia	204432|Acidobacteriia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_1290911_2	1038867.AXAY01000004_gene2673	1.741e-48	179.0	COG1846@1|root,COG1846@2|Bacteria,1RI74@1224|Proteobacteria,2UAPB@28211|Alphaproteobacteria,3JZYN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_1290911_1	682795.AciX8_2837	5.582e-85	287.0	COG1335@1|root,COG1335@2|Bacteria,3Y6WY@57723|Acidobacteria,2JKMH@204432|Acidobacteriia	204432|Acidobacteriia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
MMS3_k127_1290911_3	395963.Bind_2951	3.155e-46	170.0	2CC1B@1|root,32RUI@2|Bacteria,1N1T2@1224|Proteobacteria,2U9AM@28211|Alphaproteobacteria,3NBJH@45404|Beijerinckiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1290911_0	682795.AciX8_2839	8.412e-103	339.0	COG0477@1|root,COG2814@2|Bacteria,3Y6RJ@57723|Acidobacteria,2JM8P@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_1296485_0	1380394.JADL01000003_gene4961	9.937e-131	425.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,2JP95@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS3_k127_1296485_1	309807.SRU_2708	5.53e-122	403.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_1296485_2	742817.HMPREF9449_02993	5.867e-55	208.0	COG1626@1|root,COG1626@2|Bacteria,4PC3G@976|Bacteroidetes,2FQQD@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 63 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
MMS3_k127_1296485_3	1267535.KB906767_gene3858	8.198e-25	114.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3858|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1298787_20	441620.Mpop_3217	3.182e-15	80.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,1JR0D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_1298787_1	335543.Sfum_0972	3.074e-157	505.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,2MQTT@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_1298787_8	1382359.JIAL01000001_gene928	2.368e-74	253.0	COG0110@1|root,COG0110@2|Bacteria,3Y5CT@57723|Acidobacteria,2JNBI@204432|Acidobacteriia	204432|Acidobacteriia	JM	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
MMS3_k127_1298787_0	335543.Sfum_0974	1.138e-158	506.0	COG0673@1|root,COG0673@2|Bacteria,1QW91@1224|Proteobacteria,42S01@68525|delta/epsilon subdivisions,2X7Q1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_1298787_3	335543.Sfum_0975	1.051e-102	347.0	COG2148@1|root,COG2199@1|root,COG2148@2|Bacteria,COG3706@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria,2MRYR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Undecaprenyl-phosphate galactose phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
MMS3_k127_1298787_7	682795.AciX8_1492	4.154e-82	303.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,3Y2V7@57723|Acidobacteria,2JIYH@204432|Acidobacteriia	57723|Acidobacteria	D	G-rich domain on putative tyrosine kinase	-	-	2.7.10.1	ko:K08252,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
MMS3_k127_1298787_14	1267535.KB906767_gene2207	4.336e-47	184.0	COG1596@1|root,COG1596@2|Bacteria,3Y57H@57723|Acidobacteria,2JJNS@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
MMS3_k127_1298787_12	1267534.KB906755_gene4130	1.835e-53	195.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601,ko:K05785	-	-	-	-	ko00000,ko03000,ko03009,ko03021	-	-	-	KOW,NusG
MMS3_k127_1298787_11	1382359.JIAL01000001_gene922	5.404e-60	221.0	COG2204@1|root,COG2204@2|Bacteria,3Y4B7@57723|Acidobacteria,2JJ5G@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Sigma54_activat
MMS3_k127_1298787_9	1382359.JIAL01000001_gene922	1.209e-63	231.0	COG2204@1|root,COG2204@2|Bacteria,3Y4B7@57723|Acidobacteria,2JJ5G@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Sigma54_activat
MMS3_k127_1298787_2	1160137.KB907307_gene779	4.434e-123	401.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria,4FU8E@85025|Nocardiaceae	201174|Actinobacteria	T	STAS domain	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
MMS3_k127_1298787_16	1206739.BAGJ01000099_gene1976	3.564e-41	154.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria,4G0GD@85025|Nocardiaceae	201174|Actinobacteria	T	STAS domain	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
MMS3_k127_1298787_17	1380356.JNIK01000021_gene4648	6.979e-40	152.0	COG1595@1|root,COG2172@1|root,COG1595@2|Bacteria,COG2172@2|Bacteria,2IKM9@201174|Actinobacteria,4EWC7@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
MMS3_k127_1298787_15	667632.KB890164_gene2209	2.719e-45	171.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria	1224|Proteobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K05518	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
MMS3_k127_1298787_13	525904.Tter_0301	6.448e-49	192.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
MMS3_k127_1298787_10	1128421.JAGA01000002_gene1765	1.98e-60	215.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
MMS3_k127_1298787_18	234267.Acid_1603	8.477e-32	128.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria	57723|Acidobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1298787_6	1267535.KB906767_gene4015	5.225e-84	285.0	COG5424@1|root,COG5424@2|Bacteria,3Y718@57723|Acidobacteria,2JKMM@204432|Acidobacteriia	204432|Acidobacteriia	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
MMS3_k127_1298787_19	65393.PCC7424_4631	5.001e-29	124.0	COG1592@1|root,COG1592@2|Bacteria,1G5YD@1117|Cyanobacteria,3KJBD@43988|Cyanothece	1117|Cyanobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMS3_k127_1298787_4	97139.C824_01928	7.947e-93	316.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_1298787_5	1121481.AUAS01000011_gene5113	1.44e-90	308.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,4NFYC@976|Bacteroidetes,47K38@768503|Cytophagia	976|Bacteroidetes	K	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
MMS3_k127_130995_0	575540.Isop_3510	4.781e-63	229.0	COG1801@1|root,COG1801@2|Bacteria,2IYWM@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMS3_k127_130995_6	404589.Anae109_4101	2.394e-08	56.0	COG2227@1|root,COG2227@2|Bacteria,1RIMR@1224|Proteobacteria,43CQM@68525|delta/epsilon subdivisions,2X7Y3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_130995_1	404589.Anae109_4101	9.189e-42	156.0	COG2227@1|root,COG2227@2|Bacteria,1RIMR@1224|Proteobacteria,43CQM@68525|delta/epsilon subdivisions,2X7Y3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_130995_5	1267533.KB906743_gene818	8.901e-22	98.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_130995_4	366602.Caul_4595	1.118e-23	107.0	2ES6B@1|root,33JR3@2|Bacteria,1R6RW@1224|Proteobacteria,2U2FS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_130995_3	1218076.BAYB01000026_gene4417	1.626e-31	125.0	COG1846@1|root,COG1846@2|Bacteria,1RJ4D@1224|Proteobacteria	1224|Proteobacteria	K	TRANSCRIPTIONal	MA20_05735	-	-	-	-	-	-	-	-	-	-	-	HTH_34
MMS3_k127_130995_2	485916.Dtox_4336	1.447e-41	156.0	2C82G@1|root,32RK9@2|Bacteria,1VZ8X@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
MMS3_k127_1315708_3	395019.Bmul_0700	3.301e-104	350.0	COG0524@1|root,COG0524@2|Bacteria,1NF0X@1224|Proteobacteria,2VIH7@28216|Betaproteobacteria,1K672@119060|Burkholderiaceae	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	scrK	-	2.7.1.101,2.7.1.4	ko:K00847,ko:K21621	ko00051,ko00052,ko00500,ko00520,ko01100,map00051,map00052,map00500,map00520,map01100	-	R00760,R00867,R02927,R03920	RC00002,RC00017,RC00810	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_1315708_1	234267.Acid_4055	1.892e-147	485.0	COG0823@1|root,COG0823@2|Bacteria,3Y2NB@57723|Acidobacteria	57723|Acidobacteria	U	Oligogalacturonate lyase	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase22
MMS3_k127_1315708_6	469383.Cwoe_4585	3.971e-69	244.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS3_k127_1315708_4	1123261.AXDW01000005_gene2667	3.4e-97	327.0	COG1682@1|root,COG1682@2|Bacteria,1QXTH@1224|Proteobacteria,1SPS5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
MMS3_k127_1315708_2	404589.Anae109_1617	3.245e-107	354.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42ZGK@68525|delta/epsilon subdivisions,2WUTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1315708_5	240015.ACP_1056	1.606e-85	291.0	COG1295@1|root,COG1295@2|Bacteria,3Y3RZ@57723|Acidobacteria,2JIYV@204432|Acidobacteriia	204432|Acidobacteriia	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
MMS3_k127_1315708_7	1382359.JIAL01000001_gene698	9.603e-33	136.0	2B5NQ@1|root,31YI3@2|Bacteria,3Y9FC@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
MMS3_k127_1315708_0	1267535.KB906767_gene4662	1.122e-184	587.0	COG0477@1|root,COG2814@2|Bacteria,3Y9FM@57723|Acidobacteria,2JP7Y@204432|Acidobacteriia	2|Bacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K02100	-	-	-	-	ko00000,ko02000	2.A.1.1.2	-	-	Sugar_tr
MMS3_k127_1321815_0	1267535.KB906767_gene2437	3.241e-59	220.0	COG1506@1|root,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria,2JHN3@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
MMS3_k127_1321815_1	935845.JADQ01000006_gene1815	8.818e-25	120.0	2CABP@1|root,2Z7KZ@2|Bacteria,1VY63@1239|Firmicutes,4HXQM@91061|Bacilli,275VV@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1324524_6	1123020.AUIE01000002_gene1690	1.936e-66	241.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,1YFDC@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Trp_halogenase
MMS3_k127_1324524_1	745411.B3C1_04455	3.288e-232	737.0	28IH4@1|root,2Z8IE@2|Bacteria,1N4IS@1224|Proteobacteria,1RNXT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	GO:0001716,GO:0001906,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016641,GO:0031640,GO:0033736,GO:0035821,GO:0043900,GO:0043901,GO:0044364,GO:0044419,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051704,GO:0055114,GO:0065007,GO:1900190,GO:1900191	1.4.3.20	ko:K17831	-	-	-	-	ko00000,ko01000	-	-	-	-
MMS3_k127_1324524_3	1120999.JONM01000034_gene3996	3.137e-107	360.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,2VH6J@28216|Betaproteobacteria,2KPKS@206351|Neisseriales	206351|Neisseriales	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
MMS3_k127_1324524_0	1463934.JOCF01000007_gene1330	0.0	1054.0	COG0753@1|root,COG0753@2|Bacteria,2I4NI@201174|Actinobacteria	201174|Actinobacteria	P	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1324524_8	1449063.JMLS01000009_gene2180	1.399e-14	79.0	COG4977@1|root,COG4977@2|Bacteria,1VZ1V@1239|Firmicutes,4HYKF@91061|Bacilli,26SST@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
MMS3_k127_1324524_2	616991.JPOO01000003_gene1738	2.169e-158	514.0	COG2730@1|root,COG2730@2|Bacteria,4NF3J@976|Bacteroidetes,1I1P4@117743|Flavobacteriia	976|Bacteroidetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
MMS3_k127_1324524_5	1343740.M271_40275	2.064e-76	266.0	COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria	201174|Actinobacteria	EM	Belongs to the DapA family	dapA_1	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_1324524_4	1123368.AUIS01000005_gene309	8.742e-102	348.0	COG2271@1|root,COG2271@2|Bacteria,1QV3V@1224|Proteobacteria	1224|Proteobacteria	G	response to oxidative stress	yaaU	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K08368	-	-	-	-	ko00000,ko02000	2.A.1	-	-	Sugar_tr
MMS3_k127_1324524_7	1267535.KB906767_gene1816	5.812e-60	220.0	COG3395@1|root,COG3395@2|Bacteria	2|Bacteria	S	kinase activity	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
MMS3_k127_1341672_1	204669.Acid345_4296	1.011e-104	351.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_1341672_0	1382359.JIAL01000001_gene1018	6.537e-121	408.0	COG0358@1|root,COG0358@2|Bacteria,3Y366@57723|Acidobacteria,2JIHT@204432|Acidobacteriia	204432|Acidobacteriia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
MMS3_k127_134710_1	1267534.KB906757_gene1073	1.192e-147	481.0	COG0457@1|root,COG0457@2|Bacteria,3Y6WQ@57723|Acidobacteria,2JKRM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2
MMS3_k127_134710_0	1267535.KB906767_gene4330	2.136e-172	549.0	COG3119@1|root,COG3119@2|Bacteria,3Y2QE@57723|Acidobacteria,2JKHV@204432|Acidobacteriia	204432|Acidobacteriia	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_134710_2	1267534.KB906757_gene1071	3.037e-129	427.0	28MYB@1|root,2ZB57@2|Bacteria,3Y32P@57723|Acidobacteria,2JMJR@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_134710_3	1267534.KB906757_gene1073	1.506e-35	145.0	COG0457@1|root,COG0457@2|Bacteria,3Y6WQ@57723|Acidobacteria,2JKRM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2
MMS3_k127_1348743_3	1382359.JIAL01000001_gene2722	3.791e-19	90.0	COG2152@1|root,COG2152@2|Bacteria,3Y2JA@57723|Acidobacteria,2JJ9E@204432|Acidobacteriia	204432|Acidobacteriia	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	3.2.1.197	ko:K21065	-	-	R11544	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
MMS3_k127_1348743_0	204669.Acid345_0153	6.517e-192	612.0	COG0439@1|root,COG0439@2|Bacteria,3Y3FH@57723|Acidobacteria,2JKRD@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
MMS3_k127_1348743_2	234267.Acid_1859	1.316e-22	104.0	COG4770@1|root,COG4770@2|Bacteria,3Y5QJ@57723|Acidobacteria	57723|Acidobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
MMS3_k127_1348743_1	204669.Acid345_0157	4.195e-75	267.0	COG0760@1|root,COG0760@2|Bacteria,3Y42Z@57723|Acidobacteria,2JHQ4@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
MMS3_k127_1348743_4	682795.AciX8_0504	1.67e-14	80.0	COG0227@1|root,COG0227@2|Bacteria,3Y5KC@57723|Acidobacteria,2JJYY@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
MMS3_k127_135283_3	234267.Acid_1283	3.341e-08	56.0	COG0848@1|root,COG0848@2|Bacteria,3Y5AP@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
MMS3_k127_135283_1	1382359.JIAL01000001_gene981	2.195e-57	209.0	COG0457@1|root,COG0457@2|Bacteria,3Y3N5@57723|Acidobacteria,2JISD@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
MMS3_k127_135283_0	1382359.JIAL01000001_gene1097	6.358e-292	911.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria,2JIN0@204432|Acidobacteriia	204432|Acidobacteriia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
MMS3_k127_135283_2	401053.AciPR4_0433	7.366e-25	105.0	COG0227@1|root,COG0227@2|Bacteria,3Y5KC@57723|Acidobacteria,2JJYY@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
MMS3_k127_135525_1	518766.Rmar_1007	8.337e-27	120.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1FJR9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_135525_2	255470.cbdbA34	1.676e-15	83.0	COG0589@1|root,COG0589@2|Bacteria,2G7D7@200795|Chloroflexi,34DAT@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_135525_4	658187.LDG_5860	1.554e-05	50.0	2ENCP@1|root,33G06@2|Bacteria,1P756@1224|Proteobacteria,1SU1K@1236|Gammaproteobacteria,1JF0F@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_135525_3	1121861.KB899919_gene2739	8.662e-15	78.0	2DRFR@1|root,33BIP@2|Bacteria,1NNWC@1224|Proteobacteria,2UXP8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
MMS3_k127_135525_0	330214.NIDE1491	2.084e-53	204.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
MMS3_k127_1367706_2	1449126.JQKL01000070_gene3530	1.684e-37	151.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
MMS3_k127_1367706_1	1267535.KB906767_gene3022	4.371e-70	243.0	COG2197@1|root,COG2197@2|Bacteria,3Y4RA@57723|Acidobacteria,2JMRJ@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1367706_0	1267535.KB906767_gene3021	4.732e-86	302.0	COG4585@1|root,COG4585@2|Bacteria,3Y3UD@57723|Acidobacteria,2JKVP@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
MMS3_k127_139706_2	935845.JADQ01000007_gene1676	2.171e-58	209.0	COG0329@1|root,COG0329@2|Bacteria,1U034@1239|Firmicutes,4I9D8@91061|Bacilli,271D2@186822|Paenibacillaceae	91061|Bacilli	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
MMS3_k127_139706_5	1267535.KB906767_gene1664	8.024e-19	93.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria,2JITG@204432|Acidobacteriia	2|Bacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
MMS3_k127_139706_1	1267533.KB906737_gene1819	1.245e-175	558.0	COG3288@1|root,COG3288@2|Bacteria,3Y2S0@57723|Acidobacteria,2JM52@204432|Acidobacteriia	204432|Acidobacteriia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
MMS3_k127_139706_4	1382359.JIAL01000001_gene95	9.722e-40	149.0	COG3288@1|root,COG3288@2|Bacteria,3Y5PH@57723|Acidobacteria,2JNMU@204432|Acidobacteriia	204432|Acidobacteriia	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
MMS3_k127_139706_0	1267533.KB906737_gene1821	3.815e-214	673.0	COG1282@1|root,COG1282@2|Bacteria,3Y42H@57723|Acidobacteria,2JM1F@204432|Acidobacteriia	204432|Acidobacteriia	C	NAD(P) transhydrogenase beta subunit	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
MMS3_k127_139706_3	1267535.KB906767_gene3595	1.052e-41	164.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMS3_k127_1397997_4	1267535.KB906767_gene3595	4.698e-43	168.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMS3_k127_1397997_2	1382359.JIAL01000001_gene2527	1.424e-90	300.0	COG1945@1|root,COG1945@2|Bacteria,3Y3KR@57723|Acidobacteria,2JIBD@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	-	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
MMS3_k127_1397997_0	1379698.RBG1_1C00001G0709	1.106e-117	389.0	COG1899@1|root,COG1899@2|Bacteria,2NR8I@2323|unclassified Bacteria	2|Bacteria	O	Deoxyhypusine synthase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
MMS3_k127_1397997_1	1340493.JNIF01000003_gene1313	2.694e-99	339.0	COG0673@1|root,COG0673@2|Bacteria,3Y4RG@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_1397997_3	234267.Acid_5201	2.585e-46	174.0	COG1477@1|root,COG1477@2|Bacteria,3Y4B0@57723|Acidobacteria	57723|Acidobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMS3_k127_143221_0	204669.Acid345_2032	6.534e-149	485.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
MMS3_k127_143221_2	1382359.JIAL01000001_gene2062	6.127e-112	380.0	COG0265@1|root,COG0265@2|Bacteria,3Y2SD@57723|Acidobacteria,2JI16@204432|Acidobacteriia	204432|Acidobacteriia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_143221_4	314262.MED193_12698	6.092e-07	57.0	COG3409@1|root,COG3409@2|Bacteria,1QVVX@1224|Proteobacteria,2UMGA@28211|Alphaproteobacteria,2P4DI@2433|Roseobacter	28211|Alphaproteobacteria	M	Type VI secretion system VasI, EvfG, VC_A0118	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
MMS3_k127_143221_3	234267.Acid_4988	3.347e-62	224.0	COG2930@1|root,COG2930@2|Bacteria,3Y2F0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
MMS3_k127_143221_1	1379698.RBG1_1C00001G0471	9.548e-126	407.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_1451887_0	452637.Oter_1878	1.752e-138	469.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1451887_1	1267535.KB906767_gene4697	1.396e-117	386.0	COG1082@1|root,COG1082@2|Bacteria,3Y88X@57723|Acidobacteria,2JP34@204432|Acidobacteriia	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_1451887_2	1267535.KB906767_gene3577	2.283e-109	372.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMS3_k127_1481664_1	1267535.KB906767_gene2857	6.07e-108	362.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Peptidase_S9
MMS3_k127_1481664_0	204669.Acid345_4120	4.042e-167	540.0	COG0147@1|root,COG0147@2|Bacteria,3Y2UX@57723|Acidobacteria,2JIMP@204432|Acidobacteriia	204432|Acidobacteriia	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
MMS3_k127_1481664_2	240015.ACP_1704	3.736e-75	256.0	COG0668@1|root,COG0668@2|Bacteria,3Y4K3@57723|Acidobacteria,2JJAD@204432|Acidobacteriia	57723|Acidobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
MMS3_k127_152350_0	247490.KSU1_C0704	1.713e-165	529.0	COG0841@1|root,COG0841@2|Bacteria,2IY6W@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07788	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
MMS3_k127_152350_1	269799.Gmet_1651	2.209e-110	368.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,43US6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMS3_k127_152350_4	1463909.KL585964_gene3846	0.0001212	54.0	COG0449@1|root,COG0449@2|Bacteria,2GP4W@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
MMS3_k127_152350_2	204669.Acid345_0267	2.842e-16	82.0	COG1396@1|root,COG1396@2|Bacteria,3Y52W@57723|Acidobacteria,2JJE1@204432|Acidobacteriia	204432|Acidobacteriia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMS3_k127_152350_3	1123057.P872_21400	1.244e-07	57.0	COG0673@1|root,COG0673@2|Bacteria,4NGTW@976|Bacteroidetes,47MX9@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_1625607_2	234267.Acid_6712	2.508e-22	98.0	COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria	57723|Acidobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
MMS3_k127_1625607_4	1267534.KB906759_gene1642	2.038e-10	70.0	COG0810@1|root,COG0810@2|Bacteria,3Y6C7@57723|Acidobacteria,2JKQM@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
MMS3_k127_1625607_3	639030.JHVA01000001_gene1123	1.585e-11	76.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
MMS3_k127_1625607_1	234267.Acid_2809	2.457e-67	237.0	COG0566@1|root,COG0566@2|Bacteria,3Y3XM@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
MMS3_k127_1625607_0	204669.Acid345_0051	5.585e-168	542.0	COG0008@1|root,COG0008@2|Bacteria,3Y465@57723|Acidobacteria,2JHZW@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMS3_k127_1625607_5	204669.Acid345_3120	5.415e-09	68.0	COG3409@1|root,COG3409@2|Bacteria,3Y4NB@57723|Acidobacteria,2JIBG@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1643154_0	234267.Acid_7504	1.69e-207	655.0	COG1032@1|root,COG1032@2|Bacteria,3Y2QU@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_1643154_4	861299.J421_4501	8.091e-30	131.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_4501|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1643154_3	1382359.JIAL01000001_gene2202	5.419e-122	402.0	COG0761@1|root,COG0761@2|Bacteria,3Y40M@57723|Acidobacteria,2JIXC@204432|Acidobacteriia	204432|Acidobacteriia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS3_k127_1643154_1	1303518.CCALI_01615	1.538e-203	653.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
MMS3_k127_1643154_2	575540.Isop_2284	2.869e-147	473.0	COG0535@1|root,COG0535@2|Bacteria,2IWZK@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Fer4_14,Radical_SAM
MMS3_k127_1645021_2	573413.Spirs_3098	3.432e-105	361.0	COG0535@1|root,COG0535@2|Bacteria,2J83E@203691|Spirochaetes	203691|Spirochaetes	S	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
MMS3_k127_1645021_1	1499967.BAYZ01000179_gene4631	3.436e-110	368.0	COG0153@1|root,COG0153@2|Bacteria,2NNYM@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
MMS3_k127_1645021_3	663278.Ethha_0759	6.692e-105	350.0	COG1085@1|root,COG1085@2|Bacteria,1TS3F@1239|Firmicutes,249P3@186801|Clostridia,3WHA1@541000|Ruminococcaceae	186801|Clostridia	H	galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
MMS3_k127_1645021_0	204669.Acid345_2881	3.42e-160	510.0	COG1060@1|root,COG1060@2|Bacteria,3Y2IA@57723|Acidobacteria,2JIBR@204432|Acidobacteriia	204432|Acidobacteriia	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
MMS3_k127_1645021_4	204669.Acid345_3342	6.867e-71	248.0	COG1427@1|root,COG1427@2|Bacteria,3Y3PU@57723|Acidobacteria,2JIWB@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
MMS3_k127_1645021_5	1267533.KB906734_gene4201	1.256e-54	198.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
MMS3_k127_1645635_5	204669.Acid345_0035	7.216e-67	233.0	COG0313@1|root,COG0313@2|Bacteria,3Y32N@57723|Acidobacteria,2JIGR@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
MMS3_k127_1645635_7	204669.Acid345_0034	2.942e-21	106.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria,2JJW0@204432|Acidobacteriia	204432|Acidobacteriia	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_1645635_6	756272.Plabr_4030	1.787e-64	225.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_1645635_2	234267.Acid_1043	5.118e-112	368.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_1645635_3	1267535.KB906767_gene399	1.664e-110	368.0	COG0533@1|root,COG0533@2|Bacteria,3Y2PN@57723|Acidobacteria,2JHJ0@204432|Acidobacteriia	204432|Acidobacteriia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
MMS3_k127_1645635_1	204669.Acid345_2039	1.645e-183	599.0	COG0145@1|root,COG0145@2|Bacteria,3Y6D5@57723|Acidobacteria,2JKXC@204432|Acidobacteriia	204432|Acidobacteriia	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_1645635_0	204669.Acid345_3921	2.033e-211	669.0	COG0146@1|root,COG0146@2|Bacteria,3Y6W2@57723|Acidobacteria,2JKCE@204432|Acidobacteriia	204432|Acidobacteriia	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_1645635_4	1303518.CCALI_00462	7.303e-75	262.0	COG1446@1|root,COG1446@2|Bacteria	2|Bacteria	E	asparaginase	asnA2	-	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
MMS3_k127_1649948_2	204669.Acid345_3631	1.779e-109	372.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_1649948_1	204669.Acid345_3630	4.716e-115	381.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
MMS3_k127_1649948_4	204669.Acid345_3629	1.62e-81	285.0	COG0707@1|root,COG0707@2|Bacteria,3Y48B@57723|Acidobacteria,2JIYA@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
MMS3_k127_1649948_0	1232410.KI421421_gene3865	1.176e-153	499.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,43T1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	UDP-N-acetylmuramate-L-alanine ligase activity	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_1649948_5	926566.Terro_3440	4.683e-42	166.0	COG1589@1|root,COG1589@2|Bacteria,3Y3BQ@57723|Acidobacteria,2JIZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
MMS3_k127_1649948_3	204669.Acid345_3452	5.476e-105	355.0	COG0849@1|root,COG0849@2|Bacteria,3Y432@57723|Acidobacteria,2JI1Q@204432|Acidobacteriia	204432|Acidobacteriia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
MMS3_k127_1649948_6	1267533.KB906733_gene3388	1.779e-25	107.0	COG0206@1|root,COG0206@2|Bacteria,3Y2WG@57723|Acidobacteria,2JHRJ@204432|Acidobacteriia	204432|Acidobacteriia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMS3_k127_1653538_0	1267535.KB906767_gene2916	1.005e-211	666.0	COG0277@1|root,COG0277@2|Bacteria,3Y36Q@57723|Acidobacteria	57723|Acidobacteria	C	PFAM FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
MMS3_k127_1653538_1	1042377.AFPJ01000028_gene2288	3.174e-178	576.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,466AY@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_7
MMS3_k127_1653538_2	794903.OPIT5_07060	6.428e-26	108.0	COG2120@1|root,COG2120@2|Bacteria,46TIV@74201|Verrucomicrobia,3K78W@414999|Opitutae	414999|Opitutae	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_1655087_6	234267.Acid_0298	4.908e-108	367.0	COG1570@1|root,COG1570@2|Bacteria,3Y3DP@57723|Acidobacteria	57723|Acidobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
MMS3_k127_1655087_8	338966.Ppro_1650	1.698e-13	76.0	COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,42WU5@68525|delta/epsilon subdivisions,2WRRS@28221|Deltaproteobacteria,43SRB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
MMS3_k127_1655087_7	234267.Acid_0682	1.992e-85	293.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	glkA	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMS3_k127_1655087_4	1267535.KB906767_gene191	9.528e-160	518.0	COG1231@1|root,COG1231@2|Bacteria,3Y895@57723|Acidobacteria,2JNAN@204432|Acidobacteriia	204432|Acidobacteriia	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMS3_k127_1655087_1	639030.JHVA01000001_gene1923	8.533e-223	717.0	COG0457@1|root,COG0457@2|Bacteria,3Y93T@57723|Acidobacteria	57723|Acidobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_8
MMS3_k127_1655087_0	1267534.KB906757_gene1074	0.0	1254.0	COG1629@1|root,COG1629@2|Bacteria,3Y72I@57723|Acidobacteria,2JKKK@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
MMS3_k127_1655087_5	1267534.KB906757_gene1073	1.463e-141	463.0	COG0457@1|root,COG0457@2|Bacteria,3Y6WQ@57723|Acidobacteria,2JKRM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2
MMS3_k127_1655087_3	204669.Acid345_3257	9.523e-183	580.0	COG4867@1|root,COG4867@2|Bacteria,3Y2VU@57723|Acidobacteria,2JHSR@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
MMS3_k127_1655087_2	1382359.JIAL01000001_gene2230	1.063e-200	636.0	COG1239@1|root,COG1239@2|Bacteria,3Y3FM@57723|Acidobacteria,2JHY2@204432|Acidobacteriia	204432|Acidobacteriia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Sigma54_activat
MMS3_k127_1657686_7	1267533.KB906738_gene2273	2.489e-31	129.0	COG2172@1|root,COG2172@2|Bacteria,3Y4TY@57723|Acidobacteria,2JJGJ@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
MMS3_k127_1657686_5	1382359.JIAL01000001_gene2134	1.985e-46	169.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
MMS3_k127_1657686_4	204669.Acid345_1637	1.881e-59	218.0	COG1191@1|root,COG1191@2|Bacteria,3Y4Q5@57723|Acidobacteria,2JI2A@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_1657686_8	765698.Mesci_4870	4.136e-06	57.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MW8M@1224|Proteobacteria,2TUSJ@28211|Alphaproteobacteria,43HYF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Histidine kinase	ragB	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1657686_1	204669.Acid345_1658	1.276e-84	285.0	COG0745@1|root,COG0745@2|Bacteria,3Y522@57723|Acidobacteria,2JP4G@204432|Acidobacteriia	204432|Acidobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1657686_0	404380.Gbem_3819	2.66e-124	414.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U2Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_1657686_2	671143.DAMO_2838	2.682e-83	295.0	COG4191@1|root,COG4191@2|Bacteria,2NQ9P@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1657686_3	504472.Slin_3895	2.628e-76	269.0	COG1312@1|root,COG1312@2|Bacteria,4NF30@976|Bacteroidetes,47N1H@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
MMS3_k127_1657686_6	1267535.KB906767_gene1399	2.313e-45	166.0	COG0684@1|root,COG0684@2|Bacteria,3Y7HG@57723|Acidobacteria	57723|Acidobacteria	M	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
MMS3_k127_1658326_0	644966.Tmar_1638	5.138e-203	642.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WCWS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
MMS3_k127_1658326_6	1267534.KB906759_gene1736	0.0004606	51.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_1658326_1	439235.Dalk_3095	5.713e-78	265.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MJGI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
MMS3_k127_1658326_4	1082931.KKY_2436	2.181e-10	63.0	2EFVW@1|root,339N3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1658326_5	1382359.JIAL01000001_gene1562	4.649e-08	61.0	29ITM@1|root,305QZ@2|Bacteria,3Y4F3@57723|Acidobacteria,2JJ2C@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1660972_0	1267535.KB906767_gene5352	0.0	1157.0	COG0841@1|root,COG0841@2|Bacteria,3Y3F4@57723|Acidobacteria,2JIHS@204432|Acidobacteriia	204432|Acidobacteriia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMS3_k127_1660972_2	1183438.GKIL_0711	2.063e-41	158.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS3_k127_1660972_3	240015.ACP_2093	3.584e-11	70.0	COG1826@1|root,COG1826@2|Bacteria,3Y5GD@57723|Acidobacteria,2JJZP@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_1660972_1	1121904.ARBP01000003_gene6571	2.907e-66	239.0	COG1820@1|root,COG1820@2|Bacteria,4NJ35@976|Bacteroidetes,47KJ5@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMS3_k127_1669767_2	234267.Acid_6299	9.526e-28	118.0	COG0130@1|root,COG0130@2|Bacteria,3Y3PG@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
MMS3_k127_1669767_3	28444.JODQ01000007_gene5583	8.255e-05	53.0	COG1280@1|root,COG1280@2|Bacteria,2INXA@201174|Actinobacteria,4EPSU@85012|Streptosporangiales	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
MMS3_k127_1669767_1	1379698.RBG1_1C00001G1008	3.141e-141	458.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
MMS3_k127_1669767_0	204669.Acid345_1286	7.014e-200	634.0	COG1190@1|root,COG1190@2|Bacteria,3Y3N0@57723|Acidobacteria,2JI1W@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS3_k127_1675973_1	743836.AYNA01000104_gene2059	3.18e-44	171.0	COG1215@1|root,COG1215@2|Bacteria,1R8UT@1224|Proteobacteria,2TVQT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21
MMS3_k127_1675973_2	886293.Sinac_2356	3.55e-43	173.0	COG1215@1|root,COG1215@2|Bacteria,2J02Q@203682|Planctomycetes	203682|Planctomycetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1675973_0	1047013.AQSP01000112_gene393	4.849e-104	355.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	cpsE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3,STAS
MMS3_k127_1691513_3	1267535.KB906767_gene3160	3.089e-21	94.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria,2JHJM@204432|Acidobacteriia	204432|Acidobacteriia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
MMS3_k127_1691513_2	717231.Flexsi_0985	1.207e-21	102.0	COG1544@1|root,COG1544@2|Bacteria,2GFDP@200930|Deferribacteres	200930|Deferribacteres	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
MMS3_k127_1691513_0	234267.Acid_7397	3.409e-165	532.0	COG1508@1|root,COG1508@2|Bacteria,3Y2M0@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
MMS3_k127_1691513_1	1340493.JNIF01000003_gene2837	2.586e-108	355.0	COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
MMS3_k127_1691513_4	644282.Deba_1959	2.104e-08	67.0	COG1934@1|root,COG1934@2|Bacteria,1RM28@1224|Proteobacteria,42V9N@68525|delta/epsilon subdivisions,2WRB1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM lipopolysaccharide transport periplasmic protein LptA	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
MMS3_k127_1693198_0	1047013.AQSP01000139_gene2322	1.049e-98	331.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
MMS3_k127_1693198_3	1125863.JAFN01000001_gene2206	8.262e-62	222.0	COG0730@1|root,COG0730@2|Bacteria,1NJ47@1224|Proteobacteria,42P2D@68525|delta/epsilon subdivisions,2WKSQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_1693198_2	682795.AciX8_3935	5.004e-64	228.0	2905E@1|root,2ZMVA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
MMS3_k127_1693198_6	221288.JH992901_gene1687	2.796e-35	138.0	COG1695@1|root,COG1695@2|Bacteria,1GDRG@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_1693198_7	1434929.X946_1407	2.098e-31	131.0	2BTYX@1|root,32P7E@2|Bacteria,1PIJH@1224|Proteobacteria,2W763@28216|Betaproteobacteria,1KDWY@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1693198_4	1434929.X946_1406	6.375e-51	187.0	2A7IH@1|root,30WG9@2|Bacteria,1PI5A@1224|Proteobacteria,2W6RE@28216|Betaproteobacteria,1KCEP@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1693198_5	234267.Acid_0436	2.087e-38	151.0	COG2010@1|root,COG2010@2|Bacteria,3Y5EA@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMS3_k127_1693198_8	1283300.ATXB01000001_gene715	3.337e-28	117.0	COG0662@1|root,COG0662@2|Bacteria,1N7Q4@1224|Proteobacteria,1SEVR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_1693198_1	485913.Krac_2918	1.484e-80	284.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1400,PAF-AH_p_II
MMS3_k127_1693198_11	1499967.BAYZ01000123_gene2558	1.05e-05	53.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
MMS3_k127_1693198_9	234267.Acid_6264	1.262e-25	109.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_1693198_10	204669.Acid345_0335	3.651e-16	78.0	COG0308@1|root,COG0308@2|Bacteria,3Y3ZS@57723|Acidobacteria,2JK79@204432|Acidobacteriia	204432|Acidobacteriia	E	Phospholipase B	-	-	-	-	-	-	-	-	-	-	-	-	Phospholip_B
MMS3_k127_170909_1	56107.Cylst_1796	2.042e-99	332.0	COG1063@1|root,COG1063@2|Bacteria,1G360@1117|Cyanobacteria,1HJDW@1161|Nostocales	2|Bacteria	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_170909_0	1210884.HG799478_gene15504	4.779e-107	359.0	COG0451@1|root,COG0451@2|Bacteria,2IYKN@203682|Planctomycetes	203682|Planctomycetes	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_170909_2	635013.TherJR_1929	5.061e-60	216.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,260JN@186807|Peptococcaceae	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
MMS3_k127_1710095_2	204669.Acid345_0915	1.939e-78	274.0	COG0457@1|root,COG0457@2|Bacteria,3Y4MA@57723|Acidobacteria,2JJBW@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
MMS3_k127_1710095_7	5911.EAR95020	0.0002697	54.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
MMS3_k127_1710095_6	525904.Tter_1985	1.255e-08	68.0	COG5588@1|root,COG5588@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
MMS3_k127_1710095_3	661478.OP10G_4122	1.01e-73	263.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
MMS3_k127_1710095_0	234267.Acid_1990	1.4e-322	1024.0	COG1629@1|root,COG4771@2|Bacteria,3Y3YH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_1710095_1	204669.Acid345_0920	2.385e-245	772.0	COG0457@1|root,COG0457@2|Bacteria,3Y3HT@57723|Acidobacteria,2JHSD@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
MMS3_k127_1710095_4	926566.Terro_2597	1.077e-61	235.0	COG0457@1|root,COG0457@2|Bacteria,3Y4S2@57723|Acidobacteria,2JM74@204432|Acidobacteriia	204432|Acidobacteriia	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_6,TPR_8
MMS3_k127_1710095_9	3885.XP_007161683.1	0.0004876	49.0	KOG1862@1|root,KOG1862@2759|Eukaryota,37IX9@33090|Viridiplantae,3G73F@35493|Streptophyta,4JJUP@91835|fabids	35493|Streptophyta	S	GYF domain	-	-	-	ko:K18730	-	-	-	-	ko00000,ko03019	-	-	-	GYF
MMS3_k127_1710095_8	1449050.JNLE01000003_gene2600	0.0002798	43.0	COG1626@1|root,COG1626@2|Bacteria	2|Bacteria	G	alpha,alpha-trehalase activity	-	-	-	ko:K03931	-	-	-	-	ko00000	-	GH63	-	Glyco_hydro_63,Trehalase
MMS3_k127_1710095_5	1267533.KB906734_gene4379	2.319e-53	192.0	COG3118@1|root,COG3118@2|Bacteria,3Y69N@57723|Acidobacteria,2JMI3@204432|Acidobacteriia	204432|Acidobacteriia	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
MMS3_k127_1711829_2	240015.ACP_3534	1.568e-48	181.0	COG3408@1|root,COG3408@2|Bacteria,3Y6CR@57723|Acidobacteria,2JM5B@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1711829_0	1038860.AXAP01000018_gene3108	6.4e-161	527.0	COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
MMS3_k127_1711829_1	234267.Acid_0720	3.434e-95	325.0	COG2333@1|root,COG2333@2|Bacteria,3Y323@57723|Acidobacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_1711829_4	211165.AJLN01000047_gene6155	6.789e-10	68.0	COG4976@1|root,COG4976@2|Bacteria,1G290@1117|Cyanobacteria,1JJRS@1189|Stigonemataceae	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_1711829_3	861299.J421_3348	2.268e-15	81.0	COG0500@1|root,COG2226@2|Bacteria,1ZTCQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_171328_9	945713.IALB_2664	4.924e-33	137.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMS3_k127_171328_3	204669.Acid345_4495	1.276e-129	434.0	COG2027@1|root,COG2027@2|Bacteria,3Y3WF@57723|Acidobacteria,2JIBN@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
MMS3_k127_171328_2	161156.JQKW01000013_gene123	2.371e-135	439.0	COG0113@1|root,COG0113@2|Bacteria,2GH7X@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
MMS3_k127_171328_5	1267535.KB906767_gene1489	3.426e-116	406.0	COG1452@1|root,COG1452@2|Bacteria,3Y37B@57723|Acidobacteria,2JHPP@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
MMS3_k127_171328_11	204669.Acid345_0161	2.337e-07	63.0	COG1714@1|root,COG1714@2|Bacteria,3Y5I9@57723|Acidobacteria,2JJVV@204432|Acidobacteriia	204432|Acidobacteriia	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMS3_k127_171328_6	661478.OP10G_0723	6.704e-102	340.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19	ko:K01751,ko:K01754,ko:K06016,ko:K17989	ko00240,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00240,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00046,M00570	R00220,R00590,R00905,R00996,R04666	RC00096,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_171328_0	240015.ACP_3430	4.373e-255	797.0	COG3664@1|root,COG3664@2|Bacteria,3Y3B7@57723|Acidobacteria,2JKTF@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolases family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
MMS3_k127_171328_1	1267535.KB906767_gene1348	1.111e-214	681.0	COG3534@1|root,COG3534@2|Bacteria,3Y48A@57723|Acidobacteria,2JKQ1@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
MMS3_k127_171328_10	879305.HMPREF9290_1323	1.437e-28	117.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,22HNF@1570339|Peptoniphilaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
MMS3_k127_171328_8	639030.JHVA01000001_gene2413	1.33e-37	143.0	COG0211@1|root,COG0211@2|Bacteria,3Y5D8@57723|Acidobacteria,2JJPG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
MMS3_k127_171328_4	234267.Acid_3160	2.74e-129	422.0	COG0536@1|root,COG0536@2|Bacteria,3Y2J7@57723|Acidobacteria	57723|Acidobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
MMS3_k127_171328_7	204669.Acid345_0021	3.932e-47	177.0	COG1057@1|root,COG1057@2|Bacteria,3Y5D2@57723|Acidobacteria,2JJNT@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS3_k127_1718281_0	1088868.CIN_17220	2.488e-315	1001.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,2U26V@28211|Alphaproteobacteria,2JYCC@204441|Rhodospirillales	204441|Rhodospirillales	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
MMS3_k127_1721513_1	177437.HRM2_24220	0.0001089	49.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MK6F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1721513_0	1347369.CCAD010000081_gene2579	3.23e-264	835.0	COG0457@1|root,COG0457@2|Bacteria,1TPP8@1239|Firmicutes,4HCXY@91061|Bacilli,1ZE7M@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
MMS3_k127_1723481_10	1297742.A176_02245	1.969e-10	72.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,42TB9@68525|delta/epsilon subdivisions,2WXEF@28221|Deltaproteobacteria,2YW3Y@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
MMS3_k127_1723481_3	204669.Acid345_4211	1.578e-57	212.0	COG0454@1|root,COG0456@2|Bacteria,3Y3VJ@57723|Acidobacteria,2JHZ9@204432|Acidobacteriia	204432|Acidobacteriia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_1723481_2	926566.Terro_3283	2.467e-68	234.0	COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria,2JJC7@204432|Acidobacteriia	204432|Acidobacteriia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
MMS3_k127_1723481_6	234267.Acid_0794	1.2e-38	158.0	COG0392@1|root,COG0392@2|Bacteria,3Y3SG@57723|Acidobacteria	57723|Acidobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMS3_k127_1723481_4	234267.Acid_4964	4.939e-57	216.0	COG0671@1|root,COG0671@2|Bacteria,3Y6IG@57723|Acidobacteria	57723|Acidobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
MMS3_k127_1723481_0	234267.Acid_2600	9.748e-119	392.0	COG2404@1|root,COG2404@2|Bacteria,3Y98M@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1723481_8	234267.Acid_6361	1.378e-21	102.0	COG4818@1|root,COG4818@2|Bacteria,3Y5MZ@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870,zinc_ribbon_2
MMS3_k127_1723481_7	290397.Adeh_2888	1.737e-37	147.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1723481_1	1108045.GORHZ_040_00180	2.905e-91	308.0	COG0426@1|root,COG0426@2|Bacteria,2GJT6@201174|Actinobacteria	201174|Actinobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
MMS3_k127_1724239_4	913865.DOT_1368	0.0001803	47.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,262YN@186807|Peptococcaceae	186801|Clostridia	KT	Stress-responsive transcriptional regulator	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
MMS3_k127_1724239_1	234267.Acid_0789	1.082e-52	205.0	COG3595@1|root,COG3595@2|Bacteria,3Y3K3@57723|Acidobacteria	57723|Acidobacteria	C	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
MMS3_k127_1724239_0	234267.Acid_7333	1.683e-140	458.0	COG0128@1|root,COG0128@2|Bacteria,3Y3RH@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
MMS3_k127_1724239_2	526227.Mesil_0281	4.353e-09	59.0	COG0604@1|root,COG0604@2|Bacteria,1WIQ2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1724239_3	1121019.AUMN01000002_gene442	0.0001024	46.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,1W8P6@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_17414_4	234267.Acid_0438	2.206e-135	445.0	COG0664@1|root,COG4191@1|root,COG0664@2|Bacteria,COG4191@2|Bacteria,3Y99Q@57723|Acidobacteria	57723|Acidobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
MMS3_k127_17414_1	1469607.KK073768_gene4661	7.067e-245	768.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1HMXM@1161|Nostocales	1117|Cyanobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
MMS3_k127_17414_0	1267535.KB906767_gene887	1.047e-275	863.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,DUF5054,Glyco_hydro_38,Glyco_hydro_38C
MMS3_k127_17414_2	1267535.KB906767_gene3795	1.57e-219	688.0	COG0477@1|root,COG2814@2|Bacteria,3Y34C@57723|Acidobacteria,2JHZ7@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
MMS3_k127_17414_5	1267535.KB906767_gene893	1.411e-75	264.0	COG0524@1|root,COG0524@2|Bacteria,3Y4R5@57723|Acidobacteria,2JMR1@204432|Acidobacteriia	204432|Acidobacteriia	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_17414_3	1267535.KB906767_gene894	2.594e-185	593.0	COG1621@1|root,COG1621@2|Bacteria,3Y45X@57723|Acidobacteria,2JIFB@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolases family 32	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
MMS3_k127_1742481_1	204669.Acid345_1870	1.983e-100	341.0	COG0672@1|root,COG0672@2|Bacteria,3Y3XB@57723|Acidobacteria,2JI3D@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Iron permease FTR1	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318,FTR1
MMS3_k127_1742481_0	204669.Acid345_1869	1.086e-105	358.0	COG0577@1|root,COG0577@2|Bacteria,3Y36A@57723|Acidobacteria,2JIYT@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1742481_2	204669.Acid345_1868	1.336e-47	186.0	COG0577@1|root,COG0577@2|Bacteria	204669.Acid345_1868|-	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
MMS3_k127_1755369_4	926556.Echvi_1781	0.0008146	43.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1755369_2	1191523.MROS_1971	8.227e-68	232.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
MMS3_k127_1755369_1	1379270.AUXF01000004_gene3128	1.109e-113	377.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMS3_k127_1755369_0	671143.DAMO_1597	2.846e-147	474.0	COG0022@1|root,COG0022@2|Bacteria,2NNQZ@2323|unclassified Bacteria	2|Bacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2753	Biotin_lipoyl,Transket_pyr,Transketolase_C
MMS3_k127_1755369_3	671143.DAMO_1596	6.872e-53	195.0	COG0508@1|root,COG0508@2|Bacteria,2NNYD@2323|unclassified Bacteria	2|Bacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	pdhC	-	1.2.4.1,2.3.1.12	ko:K00162,ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R02569,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_1772716_0	401053.AciPR4_2736	3.766e-121	397.0	COG2133@1|root,COG2133@2|Bacteria,3Y6QT@57723|Acidobacteria,2JKW8@204432|Acidobacteriia	204432|Acidobacteriia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
MMS3_k127_1772716_2	401053.AciPR4_2731	4.606e-115	381.0	COG1609@1|root,COG1609@2|Bacteria,3Y6B3@57723|Acidobacteria,2JMEZ@204432|Acidobacteriia	204432|Acidobacteriia	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
MMS3_k127_1772716_1	1267535.KB906767_gene2182	3.122e-118	387.0	COG0657@1|root,COG0657@2|Bacteria,3Y2TC@57723|Acidobacteria,2JIM8@204432|Acidobacteriia	204432|Acidobacteriia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMS3_k127_1772716_3	215803.DB30_1157	3.773e-72	250.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,439ZV@68525|delta/epsilon subdivisions,2X2Y1@28221|Deltaproteobacteria,2YWXH@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
MMS3_k127_1772716_4	472759.Nhal_1647	1.893e-56	203.0	COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,1T3Z1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
MMS3_k127_1783869_3	1340493.JNIF01000003_gene3800	2.535e-11	74.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
MMS3_k127_1783869_1	1267535.KB906767_gene1397	3.183e-95	329.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
MMS3_k127_1783869_0	1267535.KB906767_gene4183	4.762e-110	367.0	COG0552@1|root,COG0552@2|Bacteria,3Y3JQ@57723|Acidobacteria,2JIXJ@204432|Acidobacteriia	204432|Acidobacteriia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
MMS3_k127_1783869_2	204669.Acid345_3335	5.931e-81	275.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMS3_k127_1784172_0	204669.Acid345_2654	1.342e-31	128.0	COG1051@1|root,COG1051@2|Bacteria,3Y98X@57723|Acidobacteria,2JJQ8@204432|Acidobacteriia	204432|Acidobacteriia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
MMS3_k127_1784172_2	5145.XP_001911590.1	3.952e-24	115.0	KOG0266@1|root,KOG0266@2759|Eukaryota,38B6D@33154|Opisthokonta,3NYUK@4751|Fungi,3QKYQ@4890|Ascomycota,21RM6@147550|Sordariomycetes	4751|Fungi	S	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,PNP_UDP_1,WD40
MMS3_k127_1784172_1	682795.AciX8_1212	1.284e-26	109.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
MMS3_k127_1790973_1	748280.NH8B_0056	2.526e-54	198.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1MUBE@1224|Proteobacteria,2VPRG@28216|Betaproteobacteria,2KSUP@206351|Neisseriales	206351|Neisseriales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
MMS3_k127_1790973_0	671143.DAMO_2385	3.102e-111	371.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
MMS3_k127_1790973_2	1267535.KB906767_gene707	2.137e-28	118.0	COG3536@1|root,COG3536@2|Bacteria,3Y4UI@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
MMS3_k127_1790973_3	1340493.JNIF01000003_gene1798	2.618e-10	64.0	COG3391@1|root,COG3391@2|Bacteria,3Y62F@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome D1 heme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
MMS3_k127_1811965_1	1267535.KB906767_gene3207	4.421e-146	485.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria	2|Bacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1811965_0	1267535.KB906767_gene1400	3.981e-280	884.0	COG0577@1|root,COG0577@2|Bacteria,3Y3V2@57723|Acidobacteria,2JM9M@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1811965_3	204669.Acid345_3459	1.943e-06	49.0	COG0577@1|root,COG0577@2|Bacteria,3Y6B8@57723|Acidobacteria,2JK7N@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1813085_2	314345.SPV1_10019	1.006e-89	334.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
MMS3_k127_1813085_3	575540.Isop_2636	3.023e-78	298.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,PAS_9,Response_reg,SpoIIE
MMS3_k127_1813085_4	575540.Isop_2637	3.885e-29	119.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
MMS3_k127_1813085_0	671143.DAMO_0738	0.0	1072.0	COG0058@1|root,COG0058@2|Bacteria,2NP1W@2323|unclassified Bacteria	2|Bacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
MMS3_k127_1813085_1	1123393.KB891326_gene92	6.332e-299	933.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2VH8E@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1813085_6	742727.HMPREF9447_04497	6.764e-11	64.0	COG3250@1|root,COG3507@1|root,COG3250@2|Bacteria,COG3507@2|Bacteria,4NGZD@976|Bacteroidetes,2G08E@200643|Bacteroidia,4ANAP@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
MMS3_k127_1835777_1	1403819.BATR01000150_gene5080	6.9e-158	503.0	COG0620@1|root,COG0620@2|Bacteria,46W8R@74201|Verrucomicrobia,2IWM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cobalamin-independent synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
MMS3_k127_1835777_3	234267.Acid_2865	1.075e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,3Y801@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1835777_0	1267535.KB906767_gene3474	1.444e-190	601.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_1835777_4	268407.PWYN_04630	5.642e-61	219.0	COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,4HCR4@91061|Bacilli,26R77@186822|Paenibacillaceae	91061|Bacilli	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
MMS3_k127_1835777_2	234267.Acid_2864	2.237e-95	324.0	COG1940@1|root,COG1940@2|Bacteria,3Y7MC@57723|Acidobacteria	57723|Acidobacteria	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMS3_k127_1835777_6	204669.Acid345_0082	2.377e-26	111.0	COG0776@1|root,COG0776@2|Bacteria,3Y5E1@57723|Acidobacteria,2JJN0@204432|Acidobacteriia	204432|Acidobacteriia	L	Bacterial DNA-binding protein	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMS3_k127_1835777_5	204669.Acid345_3770	8.776e-61	215.0	COG1201@1|root,COG1201@2|Bacteria,3Y348@57723|Acidobacteria,2JIVQ@204432|Acidobacteriia	204432|Acidobacteriia	L	dead deah	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMS3_k127_1839032_1	1267535.KB906767_gene4155	9.522e-43	168.0	2DPEK@1|root,331S2@2|Bacteria,3Y55A@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1839032_0	204669.Acid345_0650	1.807e-289	905.0	COG1501@1|root,COG1501@2|Bacteria,3Y3EQ@57723|Acidobacteria,2JIBM@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
MMS3_k127_1839724_3	234267.Acid_6087	6.705e-59	211.0	COG0457@1|root,COG0457@2|Bacteria,3Y4E6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_8
MMS3_k127_1839724_2	595460.RRSWK_02091	7.604e-95	326.0	COG1609@1|root,COG4977@1|root,COG1609@2|Bacteria,COG4977@2|Bacteria,2IXTX@203682|Planctomycetes	203682|Planctomycetes	K	Xylose operon regulatory protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
MMS3_k127_1839724_0	1267535.KB906767_gene228	3.269e-194	628.0	COG3420@1|root,COG3420@2|Bacteria,3Y67Z@57723|Acidobacteria	57723|Acidobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
MMS3_k127_1839724_1	379066.GAU_3552	1.94e-130	430.0	COG0473@1|root,COG0473@2|Bacteria,1ZTDX@142182|Gemmatimonadetes	2|Bacteria	C	Isocitrate/isopropylmalate dehydrogenase	ttuC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006108,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009027,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046553,GO:0046872,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_1288,ic_1306.c2207	Iso_dh
MMS3_k127_1839724_4	118173.KB235914_gene1774	1.081e-14	86.0	COG2771@1|root,COG2771@2|Bacteria,1GEA5@1117|Cyanobacteria	1117|Cyanobacteria	K	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019
MMS3_k127_1913034_4	234267.Acid_5242	2.138e-69	249.0	COG0557@1|root,COG0557@2|Bacteria,3Y3TF@57723|Acidobacteria	57723|Acidobacteria	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
MMS3_k127_1913034_2	273057.SSO1863	7.798e-106	356.0	COG0477@1|root,arCOG00132@2157|Archaea,2XRR4@28889|Crenarchaeota	28889|Crenarchaeota	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1913034_0	1173026.Glo7428_1784	0.0	1358.0	COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria	1117|Cyanobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
MMS3_k127_1913034_3	1121423.JONT01000009_gene1501	1.996e-89	305.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24GQP@186801|Clostridia,266UQ@186807|Peptococcaceae	186801|Clostridia	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1913034_1	682795.AciX8_0101	5.671e-167	531.0	COG3669@1|root,COG3669@2|Bacteria,3Y43P@57723|Acidobacteria,2JJ93@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
MMS3_k127_1915897_3	401526.TcarDRAFT_1542	5.982e-112	365.0	COG2221@1|root,COG2221@2|Bacteria,1TZD2@1239|Firmicutes	1239|Firmicutes	C	TIGRFAM sulfite reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
MMS3_k127_1915897_7	666510.ASAC_1286	1.842e-05	54.0	arCOG00022@1|root,arCOG00022@2157|Archaea,2XQTH@28889|Crenarchaeota	28889|Crenarchaeota	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMS3_k127_1915897_1	331678.Cphamn1_1855	6.923e-174	561.0	COG0493@1|root,COG0493@2|Bacteria,1FDFY@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2
MMS3_k127_1915897_4	706587.Desti_1118	6.413e-55	193.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,42SN5@68525|delta/epsilon subdivisions,2WP28@28221|Deltaproteobacteria,2MS2U@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	DsrC like protein	dsrC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
MMS3_k127_1915897_5	871963.Desdi_0245	2.125e-26	114.0	2CDHP@1|root,32RXU@2|Bacteria,1VQ7W@1239|Firmicutes,251NF@186801|Clostridia,265N8@186807|Peptococcaceae	186801|Clostridia	S	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
MMS3_k127_1915897_2	768706.Desor_1698	2.592e-120	397.0	COG2181@1|root,COG2181@2|Bacteria,1UYRK@1239|Firmicutes,24FM8@186801|Clostridia,266ZT@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitrate reductase gamma subunit	hmeC	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
MMS3_k127_1915897_0	264732.Moth_1606	2.566e-238	741.0	COG0247@1|root,COG0247@2|Bacteria,1TSC1@1239|Firmicutes,24B10@186801|Clostridia,42FPP@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	hmeD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
MMS3_k127_193532_1	1297742.A176_03595	0.0002597	54.0	COG3325@1|root,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,PA14,fn3
MMS3_k127_193532_0	1267533.KB906733_gene3362	2.333e-86	308.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
MMS3_k127_1947467_0	204669.Acid345_3659	4.47e-125	410.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,3Y40V@57723|Acidobacteria,2JI0P@204432|Acidobacteriia	204432|Acidobacteriia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
MMS3_k127_1947467_1	234267.Acid_6303	1.027e-25	118.0	COG1426@1|root,COG1426@2|Bacteria,3Y5KP@57723|Acidobacteria	57723|Acidobacteria	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
MMS3_k127_1947467_2	1254432.SCE1572_22045	8.783e-14	79.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1949888_4	1449049.JONW01000008_gene319	1.679e-41	163.0	COG4948@1|root,COG4948@2|Bacteria,1QVFR@1224|Proteobacteria,2U0VN@28211|Alphaproteobacteria,2KHK8@204458|Caulobacterales	204458|Caulobacterales	M	Alpha-glucosidase	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
MMS3_k127_1949888_3	1340493.JNIF01000003_gene4280	4.114e-48	181.0	COG1451@1|root,COG1451@2|Bacteria,3Y2SM@57723|Acidobacteria	57723|Acidobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1949888_0	204669.Acid345_2022	0.0	1274.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria,2JISM@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMS3_k127_1949888_7	926566.Terro_2470	1.444e-11	67.0	COG5660@1|root,COG5660@2|Bacteria,3Y5KK@57723|Acidobacteria,2JJW4@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMS3_k127_1949888_1	1267535.KB906767_gene3226	1.998e-58	209.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1949888_2	929562.Emtol_1742	1.608e-48	189.0	COG0122@1|root,COG0122@2|Bacteria,4NJHK@976|Bacteroidetes,47XRZ@768503|Cytophagia	976|Bacteroidetes	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
MMS3_k127_1949888_5	760192.Halhy_4503	5.366e-39	151.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
MMS3_k127_1949888_6	1382359.JIAL01000001_gene1146	3.633e-12	79.0	2DCQR@1|root,2ZEZD@2|Bacteria,3Y8W1@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
MMS3_k127_1951111_0	234267.Acid_7274	1.695e-146	473.0	COG0436@1|root,COG0436@2|Bacteria,3Y2IZ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_1951111_2	1304880.JAGB01000002_gene1921	3.74e-64	233.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,2487K@186801|Clostridia	186801|Clostridia	G	mannose-6-phosphate isomerase, class I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS19425	PMI_typeI
MMS3_k127_1951111_1	234267.Acid_4553	6.964e-93	318.0	COG0836@1|root,COG0836@2|Bacteria,3Y2W2@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
MMS3_k127_1951111_3	1267533.KB906733_gene3435	5.975e-39	151.0	COG1109@1|root,COG1109@2|Bacteria,3Y2F7@57723|Acidobacteria,2JHIV@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha beta alpha domain I	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_1954007_3	251221.35214601	4.147e-72	252.0	COG0845@1|root,COG0845@2|Bacteria,1G49W@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
MMS3_k127_1954007_0	247490.KSU1_C0704	0.0	1166.0	COG0841@1|root,COG0841@2|Bacteria,2IY6W@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07788	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
MMS3_k127_1954007_4	639030.JHVA01000001_gene2115	7.733e-36	143.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y8N8@57723|Acidobacteria,2JNIX@204432|Acidobacteriia	204432|Acidobacteriia	EG	L-rhamnose-proton symport protein (RhaT)	-	-	-	-	-	-	-	-	-	-	-	-	RhaT
MMS3_k127_1954007_1	1267535.KB906767_gene3753	1.891e-247	784.0	28J51@1|root,2Z90X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1954007_2	639030.JHVA01000001_gene1607	1.08e-122	403.0	2DBF9@1|root,2Z8X9@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4434,DUF5109,F5_F8_type_C
MMS3_k127_195568_3	1408473.JHXO01000012_gene437	1.073e-76	265.0	COG3408@1|root,COG3408@2|Bacteria,4NHHR@976|Bacteroidetes,2FQXQ@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
MMS3_k127_195568_5	234267.Acid_2835	1.252e-10	72.0	COG1322@1|root,COG1322@2|Bacteria,3Y3JC@57723|Acidobacteria	57723|Acidobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_195568_0	204669.Acid345_1744	1.094e-128	421.0	COG1063@1|root,COG1063@2|Bacteria,3Y30Y@57723|Acidobacteria,2JIRR@204432|Acidobacteriia	204432|Acidobacteriia	E	Zinc-binding dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_195568_1	1340493.JNIF01000003_gene3886	1.841e-119	396.0	COG1063@1|root,COG1063@2|Bacteria,3Y2H8@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_195568_4	765912.Thimo_3445	1.1e-12	78.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1WZQ1@135613|Chromatiales	135613|Chromatiales	F	other phosphorylase family 1	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_195568_2	1303518.CCALI_00062	4.608e-108	361.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
MMS3_k127_196223_0	1340493.JNIF01000003_gene2896	1.642e-147	477.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_196223_2	1267535.KB906767_gene587	3.537e-110	377.0	COG5002@1|root,COG5002@2|Bacteria,3Y3AX@57723|Acidobacteria,2JI3A@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_7
MMS3_k127_196223_3	56780.SYN_00981	2.215e-69	242.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657,ko:K07659,ko:K07664,ko:K11329	ko02020,ko02026,map02020,map02026	M00434,M00445,M00450,M00467,M00645,M00646,M00648,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_196223_1	204669.Acid345_3531	4.34e-115	381.0	COG0845@1|root,COG0845@2|Bacteria,3Y2F6@57723|Acidobacteria,2JI56@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
MMS3_k127_1970377_2	234267.Acid_1725	2.09e-88	299.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1970377_1	1382359.JIAL01000001_gene2865	3.44e-110	361.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1970377_0	234267.Acid_7936	3.437e-112	380.0	COG1566@1|root,COG1566@2|Bacteria,3Y9B7@57723|Acidobacteria	57723|Acidobacteria	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
MMS3_k127_1998178_18	1340493.JNIF01000003_gene3893	3.554e-38	146.0	COG0247@1|root,COG0247@2|Bacteria,3Y6NT@57723|Acidobacteria	57723|Acidobacteria	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
MMS3_k127_1998178_12	671143.DAMO_3172	5.047e-69	252.0	COG0277@1|root,COG0277@2|Bacteria,2NP55@2323|unclassified Bacteria	2|Bacteria	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_1998178_1	234267.Acid_1055	3.054e-174	558.0	COG0277@1|root,COG0277@2|Bacteria,3Y68N@57723|Acidobacteria	57723|Acidobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_1998178_13	706587.Desti_0005	1.235e-61	220.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2MRXV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
MMS3_k127_1998178_19	1406840.Q763_08585	4.508e-25	116.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia,2NSYZ@237|Flavobacterium	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS3_k127_1998178_3	204669.Acid345_3834	7.438e-136	442.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria,2JITG@204432|Acidobacteriia	2|Bacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
MMS3_k127_1998178_14	278963.ATWD01000002_gene684	4.171e-52	193.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_1998178_11	198467.NP92_14165	2.372e-69	244.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,21V90@150247|Anoxybacillus	91061|Bacilli	S	MazG nucleotide pyrophosphohydrolase domain	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
MMS3_k127_1998178_22	667014.Thein_1529	3.08e-14	79.0	2EAFJ@1|root,334IY@2|Bacteria,2GHZR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
MMS3_k127_1998178_8	234267.Acid_1840	1.197e-92	310.0	COG1235@1|root,COG1235@2|Bacteria,3Y40S@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
MMS3_k127_1998178_10	204669.Acid345_2631	2.765e-83	287.0	COG0196@1|root,COG0196@2|Bacteria,3Y34N@57723|Acidobacteria,2JIGD@204432|Acidobacteriia	204432|Acidobacteriia	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
MMS3_k127_1998178_0	644282.Deba_2444	5.351e-188	602.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,42NEJ@68525|delta/epsilon subdivisions,2WM86@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS3_k127_1998178_21	443143.GM18_3141	1.168e-14	76.0	2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
MMS3_k127_1998178_4	246194.CHY_1776	1.072e-132	434.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,42FDK@68295|Thermoanaerobacterales	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
MMS3_k127_1998178_6	204669.Acid345_1420	3.256e-106	359.0	COG0750@1|root,COG0750@2|Bacteria,3Y2KN@57723|Acidobacteria,2JI1B@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
MMS3_k127_1998178_5	1267533.KB906733_gene3586	2.753e-122	404.0	COG0743@1|root,COG0743@2|Bacteria,3Y30J@57723|Acidobacteria,2JI5H@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
MMS3_k127_1998178_17	717606.PaecuDRAFT_0605	2.775e-39	157.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,4IV81@91061|Bacilli,26SEC@186822|Paenibacillaceae	91061|Bacilli	I	Phosphatidate cytidylyltransferase	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
MMS3_k127_1998178_9	1267535.KB906767_gene2288	5.943e-90	302.0	COG0020@1|root,COG0020@2|Bacteria,3Y485@57723|Acidobacteria,2JI0B@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
MMS3_k127_1998178_7	401053.AciPR4_2495	1.897e-93	314.0	COG1692@1|root,COG1692@2|Bacteria,3Y3YJ@57723|Acidobacteria,2JIAY@204432|Acidobacteriia	204432|Acidobacteriia	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
MMS3_k127_1998178_20	926566.Terro_0665	3.709e-17	85.0	COG3027@1|root,COG3027@2|Bacteria,3Y5IJ@57723|Acidobacteria,2JJZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
MMS3_k127_1998178_2	204669.Acid345_0718	5.194e-158	522.0	COG0072@1|root,COG0072@2|Bacteria,3Y353@57723|Acidobacteria,2JIM2@204432|Acidobacteriia	204432|Acidobacteriia	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB
MMS3_k127_1998178_16	1178482.BJB45_16080	2.629e-40	150.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1XHW3@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
MMS3_k127_2001857_4	290340.AAur_2908	0.0001855	52.0	COG4961@1|root,COG4961@2|Bacteria,2GWMA@201174|Actinobacteria	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
MMS3_k127_2001857_3	1077972.ARGLB_078_00060	1.705e-05	54.0	COG4961@1|root,COG4961@2|Bacteria,2IS3K@201174|Actinobacteria	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
MMS3_k127_2001857_1	234267.Acid_1417	1.693e-86	295.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
MMS3_k127_2001857_2	234267.Acid_1416	3.722e-31	135.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C
MMS3_k127_2001857_0	1267535.KB906767_gene1397	4.207e-100	343.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
MMS3_k127_2016841_3	234267.Acid_2400	6.411e-101	341.0	COG0322@1|root,COG0758@1|root,COG0322@2|Bacteria,COG0758@2|Bacteria,3Y42M@57723|Acidobacteria	57723|Acidobacteria	LU	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
MMS3_k127_2016841_0	671143.DAMO_0060	1.068e-282	889.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168,ko:K07479	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
MMS3_k127_2016841_5	661478.OP10G_3800	1.723e-23	103.0	2DNQD@1|root,32YJR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
MMS3_k127_2016841_1	1267535.KB906767_gene3917	2.068e-139	451.0	COG3386@1|root,COG3386@2|Bacteria,3Y6Z4@57723|Acidobacteria,2JP1A@204432|Acidobacteriia	204432|Acidobacteriia	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMS3_k127_2016841_2	682795.AciX8_1043	5.912e-101	331.0	COG0110@1|root,COG0110@2|Bacteria,3Y68H@57723|Acidobacteria,2JMA4@204432|Acidobacteriia	204432|Acidobacteriia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
MMS3_k127_2016841_4	1382359.JIAL01000001_gene444	3.344e-75	263.0	COG2021@1|root,COG2021@2|Bacteria,3Y4JM@57723|Acidobacteria,2JJBE@204432|Acidobacteriia	204432|Acidobacteriia	E	alpha/beta hydrolase fold	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMS3_k127_20499_3	926550.CLDAP_15490	1.328e-122	401.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_20499_9	234267.Acid_7919	7.836e-48	183.0	COG2834@1|root,COG2834@2|Bacteria,3Y4A1@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
MMS3_k127_20499_5	204669.Acid345_0559	2.941e-103	347.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,LolA_like,MacB_PCD
MMS3_k127_20499_6	411463.EUBVEN_00936	8.415e-69	241.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,25V30@186806|Eubacteriaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_20499_13	204669.Acid345_0393	4.12e-33	138.0	COG2834@1|root,COG2834@2|Bacteria,3Y51N@57723|Acidobacteria,2JJJ7@204432|Acidobacteriia	204432|Acidobacteriia	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA,LolA_like
MMS3_k127_20499_0	204669.Acid345_2766	2.043e-139	450.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
MMS3_k127_20499_10	240015.ACP_0538	2.644e-47	179.0	COG0565@1|root,COG0565@2|Bacteria,3Y4F6@57723|Acidobacteria,2JJ6S@204432|Acidobacteriia	204432|Acidobacteriia	J	PFAM tRNA rRNA methyltransferase, SpoU	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
MMS3_k127_20499_7	204669.Acid345_4197	1.716e-65	241.0	28M4B@1|root,2ZAI9@2|Bacteria,3Y3NA@57723|Acidobacteria,2JI3J@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_20499_15	204669.Acid345_1693	1.41e-18	93.0	2E81U@1|root,332FW@2|Bacteria,3Y5IC@57723|Acidobacteria,2JJWT@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_20499_4	401053.AciPR4_2744	7.534e-118	386.0	COG1082@1|root,COG1082@2|Bacteria,3Y4ZI@57723|Acidobacteria,2JMF1@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_20499_18	1123373.ATXI01000009_gene374	3.692e-08	57.0	COG2331@1|root,COG2331@2|Bacteria,2GI34@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_20499_11	368408.Tpen_1785	4.835e-47	179.0	COG3375@1|root,arCOG04215@2157|Archaea,2XQCZ@28889|Crenarchaeota	28889|Crenarchaeota	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_20499_14	1158318.ATXC01000001_gene581	3.024e-19	93.0	COG1502@1|root,COG1502@2|Bacteria,2G44G@200783|Aquificae	200783|Aquificae	I	SMART phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
MMS3_k127_20499_12	886293.Sinac_5337	5.65e-34	137.0	COG2062@1|root,COG2062@2|Bacteria,2J1GK@203682|Planctomycetes	203682|Planctomycetes	T	phosphohistidine phosphatase, SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
MMS3_k127_20499_1	1123368.AUIS01000041_gene7	5.025e-136	443.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,2NDNG@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
MMS3_k127_20499_16	1267534.KB906756_gene335	1.545e-18	94.0	COG2010@1|root,COG2010@2|Bacteria,3Y8FR@57723|Acidobacteria,2JNE2@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMS3_k127_20499_2	357808.RoseRS_1785	1.938e-125	411.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMS3_k127_20499_8	234267.Acid_6996	4.201e-53	190.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,3Y415@57723|Acidobacteria	57723|Acidobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
MMS3_k127_2051768_0	1267535.KB906767_gene3394	1.215e-231	737.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria,2JIK1@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
MMS3_k127_2051768_1	84531.JMTZ01000028_gene92	1.22e-213	680.0	COG1874@1|root,COG1874@2|Bacteria,1NDQP@1224|Proteobacteria,1SDV3@1236|Gammaproteobacteria,1X5CP@135614|Xanthomonadales	135614|Xanthomonadales	G	beta-galactosidase	bga2	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
MMS3_k127_206846_0	204669.Acid345_3201	2.201e-123	405.0	COG0714@1|root,COG0714@2|Bacteria,3Y4G8@57723|Acidobacteria,2JKTE@204432|Acidobacteriia	204432|Acidobacteriia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
MMS3_k127_206846_2	1120965.AUBV01000004_gene940	2.111e-10	68.0	COG4194@1|root,COG4194@2|Bacteria,4NPYY@976|Bacteroidetes,47SM3@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
MMS3_k127_206846_1	234267.Acid_3785	3.238e-31	134.0	COG2823@1|root,COG2823@2|Bacteria,3Y4KR@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
MMS3_k127_2098239_20	1454004.AW11_02438	1.158e-13	74.0	COG2246@1|root,COG2246@2|Bacteria,1N87E@1224|Proteobacteria	1224|Proteobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
MMS3_k127_2098239_0	204669.Acid345_1991	8.007e-258	815.0	COG4206@1|root,COG4206@2|Bacteria,3Y3DX@57723|Acidobacteria,2JI30@204432|Acidobacteriia	204432|Acidobacteriia	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_2098239_1	204669.Acid345_0604	1.13e-133	461.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_8
MMS3_k127_2098239_11	234267.Acid_7677	8.582e-65	227.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
MMS3_k127_2098239_14	665571.STHERM_c03350	2.01e-51	190.0	COG2078@1|root,COG2078@2|Bacteria,2J7B9@203691|Spirochaetes	203691|Spirochaetes	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
MMS3_k127_2098239_16	234267.Acid_6304	6.197e-45	171.0	COG0558@1|root,COG0558@2|Bacteria,3Y520@57723|Acidobacteria	57723|Acidobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_2098239_3	240015.ACP_1034	3.873e-111	373.0	COG2262@1|root,COG2262@2|Bacteria,3Y2FK@57723|Acidobacteria,2JI0F@204432|Acidobacteriia	204432|Acidobacteriia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
MMS3_k127_2098239_19	204669.Acid345_4341	1.056e-23	102.0	COG1923@1|root,COG1923@2|Bacteria,3Y59T@57723|Acidobacteria,2JJSQ@204432|Acidobacteriia	204432|Acidobacteriia	S	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
MMS3_k127_2098239_7	204669.Acid345_4559	2.276e-89	308.0	COG0324@1|root,COG0324@2|Bacteria,3Y3CE@57723|Acidobacteria,2JICH@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
MMS3_k127_2098239_17	1382359.JIAL01000001_gene1780	3.398e-37	154.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria,2JHKT@204432|Acidobacteriia	204432|Acidobacteriia	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
MMS3_k127_2098239_5	401053.AciPR4_0101	4.167e-94	319.0	COG0673@1|root,COG0673@2|Bacteria,3Y3ET@57723|Acidobacteria,2JHRR@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_2098239_9	1382359.JIAL01000001_gene993	2.383e-83	286.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria,2JIMV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
MMS3_k127_2098239_8	204669.Acid345_0235	9.387e-85	293.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria,2JI06@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
MMS3_k127_2098239_13	1379270.AUXF01000006_gene300	2.014e-52	191.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
MMS3_k127_2098239_2	234267.Acid_4780	1.65e-115	381.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMS3_k127_2098239_15	234267.Acid_4781	7.833e-46	176.0	COG0237@1|root,COG0237@2|Bacteria,3Y4R2@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
MMS3_k127_2098239_4	1123073.KB899241_gene3460	4.634e-96	324.0	COG3291@1|root,COG3291@2|Bacteria,1QUTU@1224|Proteobacteria,1SNTI@1236|Gammaproteobacteria,1XDC9@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
MMS3_k127_2098239_18	1121875.KB907550_gene729	1.274e-34	143.0	2ET8I@1|root,33KSM@2|Bacteria,4NZEX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2098239_10	2340.JV46_27810	4.728e-80	274.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,1J6RV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
MMS3_k127_2098239_12	1123023.JIAI01000003_gene3051	8.412e-64	230.0	COG1090@1|root,COG1090@2|Bacteria,2I3Q5@201174|Actinobacteria,4EEAQ@85010|Pseudonocardiales	201174|Actinobacteria	S	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
MMS3_k127_2098239_6	234267.Acid_2876	1.327e-92	306.0	COG3509@1|root,COG3509@2|Bacteria,3Y3SY@57723|Acidobacteria	2|Bacteria	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
MMS3_k127_2174034_3	1267533.KB906735_gene5066	1.5e-15	85.0	COG1729@1|root,COG1729@2|Bacteria,3Y4ME@57723|Acidobacteria,2JJA9@204432|Acidobacteriia	204432|Acidobacteriia	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
MMS3_k127_2174034_0	204669.Acid345_3065	7.941e-210	666.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
MMS3_k127_2174034_1	278963.ATWD01000001_gene3268	4.749e-39	155.0	COG2020@1|root,COG2020@2|Bacteria,3Y53B@57723|Acidobacteria,2JJHM@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMS3_k127_2174034_2	472759.Nhal_2071	1.89e-17	87.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SEZZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
MMS3_k127_2186342_4	1356852.N008_08475	0.0004976	51.0	COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes,47NT5@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
MMS3_k127_2186342_2	278963.ATWD01000001_gene4313	4.136e-26	120.0	COG3103@1|root,COG3103@2|Bacteria,3Y3S0@57723|Acidobacteria,2JIYP@204432|Acidobacteriia	204432|Acidobacteriia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_8
MMS3_k127_2186342_1	1382306.JNIM01000001_gene3896	3.583e-57	206.0	COG2945@1|root,COG2945@2|Bacteria,2G9MQ@200795|Chloroflexi	200795|Chloroflexi	S	hydrolase of the alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
MMS3_k127_2186342_0	379066.GAU_2797	2.253e-272	854.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
MMS3_k127_2186391_1	1267535.KB906767_gene284	1.092e-80	277.0	COG0159@1|root,COG0159@2|Bacteria,3Y3X2@57723|Acidobacteria,2JI7C@204432|Acidobacteriia	204432|Acidobacteriia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
MMS3_k127_2186391_3	518766.Rmar_2267	2.505e-23	102.0	COG1605@1|root,COG1605@2|Bacteria,4PJAN@976|Bacteroidetes,1FKAA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Chorismate mutase type II	-	-	-	-	-	-	-	-	-	-	-	-	CM_2
MMS3_k127_2186391_0	240015.ACP_1767	1.059e-143	464.0	COG2876@1|root,COG2876@2|Bacteria,3Y2SV@57723|Acidobacteria,2JHNF@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
MMS3_k127_2186391_2	204669.Acid345_1162	2.812e-36	143.0	COG0287@1|root,COG0287@2|Bacteria,3Y4CK@57723|Acidobacteria,2JJ49@204432|Acidobacteriia	204432|Acidobacteriia	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
MMS3_k127_2196430_2	204669.Acid345_1209	4.874e-44	161.0	2DIW1@1|root,32UBV@2|Bacteria,3Y5BC@57723|Acidobacteria,2JJSS@204432|Acidobacteriia	204432|Acidobacteriia	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
MMS3_k127_2196430_0	204669.Acid345_1211	2.504e-123	409.0	COG0621@1|root,COG0621@2|Bacteria,3Y41R@57723|Acidobacteria,2JKPA@204432|Acidobacteriia	204432|Acidobacteriia	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
MMS3_k127_2196430_4	1267535.KB906767_gene688	4.289e-13	72.0	2EVWN@1|root,33PAB@2|Bacteria,3Y5UR@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2196430_1	234267.Acid_5924	1.17e-54	206.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,3Y3S3@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	NHL
MMS3_k127_2196430_3	1046625.AFQY01000007_gene107	1.5e-17	85.0	2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,1SDU5@1236|Gammaproteobacteria,3NP71@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2198313_5	1047013.AQSP01000043_gene53	2.415e-21	96.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMS3_k127_2198313_3	240015.ACP_0530	8.142e-48	193.0	COG4254@1|root,COG4254@2|Bacteria,3Y58Q@57723|Acidobacteria,2JJSD@204432|Acidobacteriia	204432|Acidobacteriia	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
MMS3_k127_2198313_2	204669.Acid345_3359	3.24e-81	278.0	COG1355@1|root,COG1355@2|Bacteria,3Y5Z0@57723|Acidobacteria,2JNSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
MMS3_k127_2198313_6	1340493.JNIF01000003_gene2471	5.493e-18	87.0	2EE2F@1|root,337X5@2|Bacteria,3Y5GQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2198313_0	340099.Teth39_0902	6.146e-224	705.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
MMS3_k127_2198313_1	1502770.JQMG01000001_gene1691	1.929e-148	484.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,2KKTT@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
MMS3_k127_2199117_6	204669.Acid345_3525	1.037e-12	70.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria,2JHYW@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_2199117_4	468556.AQYG01000050_gene3177	2.293e-30	127.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	ICMT,PEMT
MMS3_k127_2199117_0	240015.ACP_1982	6.078e-270	861.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6GN@57723|Acidobacteria,2JMDS@204432|Acidobacteriia	204432|Acidobacteriia	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_2199117_2	204669.Acid345_1604	1.965e-91	315.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_92,Metallophos,PA14
MMS3_k127_2199117_1	41431.PCC8801_0005	9.353e-94	316.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
MMS3_k127_2199117_3	1221522.B723_12260	1.629e-45	173.0	COG4977@1|root,COG4977@2|Bacteria,1RC4M@1224|Proteobacteria,1T209@1236|Gammaproteobacteria,1YUQQ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	K	AraC family transcriptional regulator	-	-	-	ko:K18991	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	Cupin_6,HTH_18
MMS3_k127_21996_4	1379698.RBG1_1C00001G0655	5.841e-103	347.0	COG0380@1|root,COG0380@2|Bacteria,2NPDG@2323|unclassified Bacteria	2|Bacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135	ko:K00697,ko:K13057,ko:K20436	ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130	M00815	R02737,R08946,R10525,R11239,R11250,R11306,R11497	RC00005,RC00049,RC02748,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT20,GT4	-	Glyco_transf_20
MMS3_k127_21996_10	1267534.KB906754_gene3396	1.759e-45	173.0	COG4221@1|root,COG4221@2|Bacteria,3Y6ZB@57723|Acidobacteria,2JKUG@204432|Acidobacteriia	204432|Acidobacteriia	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_21996_1	234267.Acid_7215	1.59e-185	590.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_21996_0	1267535.KB906767_gene5052	4.751e-275	861.0	COG3591@1|root,COG3591@2|Bacteria,3Y2TU@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
MMS3_k127_21996_11	1267533.KB906735_gene5102	2.878e-41	157.0	COG0203@1|root,COG0203@2|Bacteria,3Y4JF@57723|Acidobacteria,2JJ8Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
MMS3_k127_21996_3	1267533.KB906735_gene5103	1.211e-156	501.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
MMS3_k127_21996_6	204669.Acid345_1254	5.843e-82	277.0	COG0522@1|root,COG0522@2|Bacteria,3Y2I1@57723|Acidobacteria,2JHR6@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
MMS3_k127_21996_8	234267.Acid_5092	8.794e-56	198.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria	57723|Acidobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
MMS3_k127_21996_9	1267535.KB906767_gene2681	1.505e-55	198.0	COG0099@1|root,COG0099@2|Bacteria,3Y4KC@57723|Acidobacteria,2JJAF@204432|Acidobacteriia	204432|Acidobacteriia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
MMS3_k127_21996_13	694431.DESACE_01960	6.714e-11	64.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2M7HN@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
MMS3_k127_21996_12	204669.Acid345_1249	3.396e-34	132.0	COG0361@1|root,COG0361@2|Bacteria,3Y55Z@57723|Acidobacteria,2JJUQ@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
MMS3_k127_21996_5	56780.SYN_01596	6.803e-99	328.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2MQB2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMS3_k127_21996_7	580340.Tlie_0667	8.947e-69	239.0	COG0563@1|root,COG0563@2|Bacteria,3TA8N@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMS3_k127_21996_2	204669.Acid345_1246	3.538e-176	564.0	COG0201@1|root,COG0201@2|Bacteria,3Y38D@57723|Acidobacteria,2JISZ@204432|Acidobacteriia	204432|Acidobacteriia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
MMS3_k127_2201924_3	768671.ThimaDRAFT_3205	9.706e-78	265.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
MMS3_k127_2201924_7	768671.ThimaDRAFT_3206	5.819e-44	171.0	COG2084@1|root,COG2084@2|Bacteria,1MV27@1224|Proteobacteria,1SEKT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
MMS3_k127_2201924_6	487521.OCU_39710	1.031e-47	188.0	COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria,237YQ@1762|Mycobacteriaceae	201174|Actinobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
MMS3_k127_2201924_2	1163408.UU9_16893	7.077e-82	288.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1X4P8@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
MMS3_k127_2201924_0	1121423.JONT01000002_gene2186	2.774e-106	354.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,260F1@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
MMS3_k127_2201924_5	1238450.VIBNISOn1_490007	3.283e-52	197.0	COG4122@1|root,COG4122@2|Bacteria,1Q4CK@1224|Proteobacteria,1SW6D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
MMS3_k127_2201924_1	1267533.KB906735_gene4474	9.926e-90	307.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
MMS3_k127_2201924_4	1267533.KB906735_gene4475	3.14e-69	244.0	COG1215@1|root,COG1215@2|Bacteria,3Y7RU@57723|Acidobacteria,2JMZ6@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_2201924_8	690850.Desaf_0734	1.678e-31	131.0	COG0438@1|root,COG0438@2|Bacteria,1PERD@1224|Proteobacteria,42VK8@68525|delta/epsilon subdivisions,2WSBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_2201954_3	742743.HMPREF9453_00532	1.263e-14	83.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
MMS3_k127_2201954_1	234267.Acid_5390	5.877e-96	323.0	COG0053@1|root,COG0053@2|Bacteria,3Y6ZG@57723|Acidobacteria	57723|Acidobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
MMS3_k127_2201954_0	1267533.KB906735_gene4569	3.203e-103	346.0	COG2133@1|root,COG2133@2|Bacteria,3Y7A7@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
MMS3_k127_2201954_2	639030.JHVA01000001_gene1888	3.967e-32	129.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	betC	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,DUF4976,Sulfatase
MMS3_k127_2202153_0	1340493.JNIF01000003_gene2936	2.852e-163	522.0	COG1012@1|root,COG1012@2|Bacteria,3Y3V5@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.28	ko:K00141,ko:K22187	ko00040,ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00040,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667,R11768	RC00075,RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_2202153_2	1122915.AUGY01000023_gene375	2.959e-111	367.0	COG0826@1|root,COG0826@2|Bacteria,1TT8S@1239|Firmicutes,4HCNE@91061|Bacilli,26WCR@186822|Paenibacillaceae	91061|Bacilli	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
MMS3_k127_2202153_3	1267534.KB906754_gene3274	5.164e-98	351.0	COG0265@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
MMS3_k127_2202153_1	1267535.KB906767_gene4790	4.964e-117	381.0	COG5285@1|root,COG5285@2|Bacteria,3Y7AJ@57723|Acidobacteria	57723|Acidobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
MMS3_k127_2204595_1	457570.Nther_0302	1.451e-47	175.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
MMS3_k127_2204595_2	1267534.KB906760_gene1554	1.624e-15	80.0	2DD3Z@1|root,2ZGDH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2204595_0	909663.KI867150_gene786	8.295e-134	449.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,42T3U@68525|delta/epsilon subdivisions,2WPDH@28221|Deltaproteobacteria,2MRV1@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_2211457_3	1267533.KB906738_gene2297	1.587e-17	86.0	COG0531@1|root,COG0531@2|Bacteria,3Y2RG@57723|Acidobacteria,2JHMH@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_2211457_1	240015.ACP_1356	3.109e-162	524.0	COG4409@1|root,COG4409@2|Bacteria,3Y8VS@57723|Acidobacteria	57723|Acidobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2211457_0	234267.Acid_3443	1.119e-208	668.0	COG3975@1|root,COG3975@2|Bacteria,3Y411@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
MMS3_k127_2211457_2	240015.ACP_2718	2.304e-103	338.0	COG3511@1|root,COG3511@2|Bacteria,3Y2N8@57723|Acidobacteria,2JIT8@204432|Acidobacteriia	204432|Acidobacteriia	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
MMS3_k127_2219752_4	278963.ATWD01000001_gene2062	2.473e-113	375.0	COG2896@1|root,COG2896@2|Bacteria,3Y30D@57723|Acidobacteria,2JIKJ@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Mob_synth_C,Radical_SAM
MMS3_k127_2219752_3	204669.Acid345_4317	1.99e-153	492.0	COG0379@1|root,COG0379@2|Bacteria,3Y328@57723|Acidobacteria,2JHY8@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
MMS3_k127_2219752_14	234267.Acid_1194	1.541e-30	125.0	COG4911@1|root,COG4911@2|Bacteria,3Y4VB@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
MMS3_k127_2219752_0	1267535.KB906767_gene2652	6.52e-228	714.0	COG0422@1|root,COG0422@2|Bacteria,3Y2TX@57723|Acidobacteria,2JHMC@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
MMS3_k127_2219752_6	1267535.KB906767_gene2341	1.846e-85	292.0	COG1968@1|root,COG1968@2|Bacteria,3Y6B6@57723|Acidobacteria,2JKDH@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
MMS3_k127_2219752_16	43354.JOIJ01000011_gene2726	5.788e-25	113.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4E3IH@85010|Pseudonocardiales	201174|Actinobacteria	I	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_2219752_12	797209.ZOD2009_00415	1.351e-37	150.0	arCOG01781@1|root,arCOG01781@2157|Archaea,2XSY0@28890|Euryarchaeota,23RWZ@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	scm	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2219752_11	1278073.MYSTI_02455	1.589e-42	176.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMS3_k127_2219752_15	330214.NIDE2482	1.378e-27	114.0	COG2146@1|root,COG2146@2|Bacteria,3J1E7@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
MMS3_k127_2219752_7	1123242.JH636436_gene522	1.307e-64	232.0	COG1878@1|root,COG1878@2|Bacteria,2IZXG@203682|Planctomycetes	203682|Planctomycetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMS3_k127_2219752_9	941449.dsx2_1032	2.234e-62	225.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,42R8W@68525|delta/epsilon subdivisions,2WMZU@28221|Deltaproteobacteria,2M8M3@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
MMS3_k127_2219752_1	204669.Acid345_3233	6.223e-222	701.0	COG0606@1|root,COG0606@2|Bacteria,3Y3JA@57723|Acidobacteria,2JI3F@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
MMS3_k127_2219752_8	63737.Npun_F5939	3.283e-64	227.0	COG1051@1|root,COG1051@2|Bacteria,1G4H7@1117|Cyanobacteria,1HMRB@1161|Nostocales	1117|Cyanobacteria	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
MMS3_k127_2219752_13	404589.Anae109_1443	3.563e-34	132.0	COG2924@1|root,COG2924@2|Bacteria,1Q2JG@1224|Proteobacteria,433U0@68525|delta/epsilon subdivisions,2X9ZA@28221|Deltaproteobacteria,2YVYI@29|Myxococcales	28221|Deltaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
MMS3_k127_2219752_5	234267.Acid_0476	6.206e-107	362.0	COG1181@1|root,COG1181@2|Bacteria,3Y7GI@57723|Acidobacteria	57723|Acidobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
MMS3_k127_2219752_10	485913.Krac_10541	2.546e-50	188.0	COG2043@1|root,COG2043@2|Bacteria	2|Bacteria	C	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
MMS3_k127_2219752_2	1128421.JAGA01000002_gene1399	1.999e-169	543.0	COG1032@1|root,COG1032@2|Bacteria,2NQJQ@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_2219752_17	270374.MELB17_15162	0.0004167	46.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,464W3@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	iJN746.PP_4253	Cytochrome_CBB3,FixP_N
MMS3_k127_2220133_4	204669.Acid345_3357	1.522e-158	514.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
MMS3_k127_2220133_3	234267.Acid_1645	1.66e-162	525.0	COG2204@1|root,COG2204@2|Bacteria,3Y3T2@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_2220133_0	204669.Acid345_0776	0.0	1314.0	COG0178@1|root,COG0178@2|Bacteria,3Y3G9@57723|Acidobacteria,2JI80@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMS3_k127_2220133_1	1267535.KB906767_gene3187	0.0	1023.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,CarbopepD_reg_2,Plug
MMS3_k127_2220133_2	204669.Acid345_3525	1.474e-228	740.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria,2JHYW@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_2220133_6	1382359.JIAL01000001_gene2077	4.365e-67	244.0	COG0250@1|root,COG0250@2|Bacteria,3Y3I1@57723|Acidobacteria,2JHYX@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in transcription elongation, termination and antitermination	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2220133_8	1120948.KB903224_gene366	1.934e-09	67.0	2AVNR@1|root,31MFR@2|Bacteria,2HBMC@201174|Actinobacteria	1120948.KB903224_gene366|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2226996_1	1340493.JNIF01000003_gene1900	6.702e-100	338.0	COG0141@1|root,COG0141@2|Bacteria,3Y2N7@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
MMS3_k127_2226996_2	234267.Acid_3894	2.136e-62	221.0	COG1611@1|root,COG1611@2|Bacteria,3Y4RU@57723|Acidobacteria	57723|Acidobacteria	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMS3_k127_2226996_0	234267.Acid_3856	4.837e-134	436.0	COG0040@1|root,COG0040@2|Bacteria,3Y31Q@57723|Acidobacteria	57723|Acidobacteria	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
MMS3_k127_2226996_3	573370.DMR_00650	6.317e-38	146.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2WP2B@28221|Deltaproteobacteria,2MBKZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1897	PRA-CH,PRA-PH
MMS3_k127_2230457_2	204669.Acid345_3959	4.416e-38	155.0	2E2K5@1|root,32XPI@2|Bacteria,3Y59K@57723|Acidobacteria,2JP1H@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2230457_1	204669.Acid345_0062	2.798e-66	244.0	COG0037@1|root,COG0037@2|Bacteria,3Y2F2@57723|Acidobacteria,2JHX8@204432|Acidobacteriia	204432|Acidobacteriia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
MMS3_k127_2230457_0	278963.ATWD01000002_gene231	5.508e-170	541.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_2236771_7	1232410.KI421416_gene2608	5.121e-06	49.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43S4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_2236771_1	1382359.JIAL01000001_gene2945	2e-146	496.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
MMS3_k127_2236771_2	234267.Acid_0264	6.672e-101	351.0	COG1044@1|root,COG1044@2|Bacteria,3Y4K5@57723|Acidobacteria	57723|Acidobacteria	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
MMS3_k127_2236771_0	234267.Acid_0265	5.696e-166	549.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
MMS3_k127_2236771_3	204669.Acid345_2486	5.072e-77	263.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2236771_6	435908.IDSA_10925	2.027e-15	87.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,2QG24@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
MMS3_k127_2236771_5	123214.PERMA_1404	3.898e-35	140.0	COG0703@1|root,COG0703@2|Bacteria,2G46N@200783|Aquificae	200783|Aquificae	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
MMS3_k127_2236771_4	882.DVU_0327	5.621e-76	271.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria,2MA09@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
MMS3_k127_2241044_3	204669.Acid345_1515	1.508e-81	288.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
MMS3_k127_2241044_0	204669.Acid345_1516	2.714e-196	636.0	COG1449@1|root,COG1449@2|Bacteria,3Y36M@57723|Acidobacteria,2JM7G@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
MMS3_k127_2241044_4	1267533.KB906736_gene1266	4.851e-28	127.0	COG3391@1|root,COG3391@2|Bacteria,3Y3R3@57723|Acidobacteria,2JHUC@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
MMS3_k127_2241044_2	234267.Acid_5984	3.038e-85	292.0	COG0648@1|root,COG0648@2|Bacteria,3Y35C@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
MMS3_k127_2241044_1	289376.THEYE_A1204	2.87e-183	583.0	COG0495@1|root,COG0495@2|Bacteria,3J0F8@40117|Nitrospirae	40117|Nitrospirae	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
MMS3_k127_2247837_0	204669.Acid345_4231	8.811e-215	690.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
MMS3_k127_2247837_1	234267.Acid_7297	4.917e-76	270.0	COG0322@1|root,COG0322@2|Bacteria,3Y3HU@57723|Acidobacteria	57723|Acidobacteria	L	excinuclease ABC activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2247837_2	401053.AciPR4_0187	2e-75	267.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria,2JMBM@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
MMS3_k127_2253945_3	1121918.ARWE01000001_gene1379	2.869e-07	55.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,43TES@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	integrase domain protein SAM domain protein	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_2253945_1	926566.Terro_1648	1.57e-38	154.0	COG2197@1|root,COG2197@2|Bacteria,3Y40U@57723|Acidobacteria,2JHRE@204432|Acidobacteriia	204432|Acidobacteriia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_2253945_2	639030.JHVA01000001_gene560	8.333e-10	64.0	2E21T@1|root,32X9H@2|Bacteria,3Y5D6@57723|Acidobacteria,2JJQA@204432|Acidobacteriia	204432|Acidobacteriia	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
MMS3_k127_2253945_0	278963.ATWD01000002_gene371	9.031e-93	329.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NZ@57723|Acidobacteria,2JI75@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_2256413_0	240015.ACP_2445	3.035e-133	442.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_2256413_2	443143.GM18_0223	1.917e-08	61.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
MMS3_k127_2256413_1	1121116.KB894765_gene645	2.132e-09	65.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,2WEAK@28216|Betaproteobacteria,4AA7D@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM response regulator receiver	qseB	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_2256948_1	1267535.KB906767_gene4766	4.208e-121	395.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
MMS3_k127_2256948_2	234267.Acid_3576	6.013e-93	320.0	COG1600@1|root,COG1600@2|Bacteria,3Y3TQ@57723|Acidobacteria	57723|Acidobacteria	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
MMS3_k127_2256948_4	204669.Acid345_2954	4.62e-37	146.0	COG1846@1|root,COG1846@2|Bacteria,3Y5EQ@57723|Acidobacteria,2JJWZ@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_2256948_3	234267.Acid_5030	2.253e-62	223.0	COG2353@1|root,COG2353@2|Bacteria,3Y4PV@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
MMS3_k127_2256948_0	1267535.KB906767_gene2168	6.481e-198	629.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria,2JMHB@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K00256	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_2262050_4	381666.H16_A2194	3.259e-43	165.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VZ53@28216|Betaproteobacteria,1K5YJ@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Elongation factor P	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
MMS3_k127_2262050_5	234267.Acid_4520	4.167e-42	161.0	COG1335@1|root,COG1335@2|Bacteria,3Y7ZP@57723|Acidobacteria	57723|Acidobacteria	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
MMS3_k127_2262050_1	247490.KSU1_C0752	7.768e-134	441.0	COG1488@1|root,COG1488@2|Bacteria,2IXDA@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
MMS3_k127_2262050_2	1173028.ANKO01000056_gene2161	4.098e-98	342.0	COG0745@1|root,COG2202@1|root,COG4251@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG4251@2|Bacteria,1G2QC@1117|Cyanobacteria,1H7Q7@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
MMS3_k127_2262050_3	1173026.Glo7428_2204	9.968e-54	193.0	COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM response regulator receiveR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMS3_k127_2262050_0	330214.NIDE0222	5.593e-136	453.0	COG0745@1|root,COG0784@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
MMS3_k127_2262050_6	394503.Ccel_1237	4.148e-09	57.0	COG3345@1|root,COG3345@2|Bacteria,1U52C@1239|Firmicutes,25FA2@186801|Clostridia,36EVC@31979|Clostridiaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	CBM_6,Dockerin_1,Melibiase_2,Melibiase_2_C
MMS3_k127_2266162_0	1267533.KB906747_gene22	1.334e-291	902.0	COG0649@1|root,COG0649@2|Bacteria,3Y3N1@57723|Acidobacteria,2JIDU@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
MMS3_k127_2266162_2	1267535.KB906767_gene56	2.93e-101	333.0	COG0377@1|root,COG0377@2|Bacteria,3Y475@57723|Acidobacteria,2JHSW@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMS3_k127_2266162_3	1267533.KB906747_gene24	5.114e-42	157.0	COG0838@1|root,COG0838@2|Bacteria	2|Bacteria	C	NADH dehydrogenase (ubiquinone) activity	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
MMS3_k127_2266162_1	204669.Acid345_0695	2.256e-120	404.0	COG1232@1|root,COG1232@2|Bacteria,3Y2X5@57723|Acidobacteria,2JI03@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMS3_k127_2266162_4	234267.Acid_5203	7.977e-28	115.0	COG0276@1|root,COG0276@2|Bacteria,3Y3B0@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
MMS3_k127_2271486_2	1234664.AMRO01000005_gene2144	1.503e-70	260.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1WEE2@129337|Geobacillus	91061|Bacilli	L	Exodeoxyribonuclease V, gamma subunit	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
MMS3_k127_2271486_0	204669.Acid345_1070	1.684e-193	611.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria,2JI6Q@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMS3_k127_2271486_1	1267535.KB906767_gene2426	1.86e-187	599.0	COG0696@1|root,COG0696@2|Bacteria,3Y2YH@57723|Acidobacteria,2JIZ0@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
MMS3_k127_2271486_3	204669.Acid345_4251	4.642e-23	102.0	COG3209@1|root,COG3209@2|Bacteria,3Y5MY@57723|Acidobacteria,2JJXY@204432|Acidobacteriia	204432|Acidobacteriia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2274778_3	525254.HMPREF0072_0936	6.371e-12	69.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_2274778_1	204669.Acid345_0362	2.401e-49	184.0	COG0664@1|root,COG0664@2|Bacteria,3Y4WU@57723|Acidobacteria,2JMTC@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_2274778_2	234267.Acid_1042	1.591e-43	162.0	COG1146@1|root,COG1146@2|Bacteria,3Y59N@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4
MMS3_k127_2274778_0	204669.Acid345_4718	1.33e-56	209.0	COG1519@1|root,COG1519@2|Bacteria,3Y3X5@57723|Acidobacteria,2JI61@204432|Acidobacteriia	204432|Acidobacteriia	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
MMS3_k127_2275655_8	289376.THEYE_A1450	8.188e-35	135.0	COG0049@1|root,COG0049@2|Bacteria,3J0HK@40117|Nitrospirae	40117|Nitrospirae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
MMS3_k127_2275655_4	682795.AciX8_0568	1.101e-65	226.0	COG0048@1|root,COG0048@2|Bacteria,3Y4JQ@57723|Acidobacteria,2JJ7D@204432|Acidobacteriia	204432|Acidobacteriia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
MMS3_k127_2275655_3	234267.Acid_0903	7.766e-70	241.0	COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
MMS3_k127_2275655_1	1121468.AUBR01000029_gene1586	2.821e-95	317.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,42EJV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
MMS3_k127_2275655_2	1382359.JIAL01000001_gene1356	2.31e-72	249.0	COG0264@1|root,COG0264@2|Bacteria,3Y3BT@57723|Acidobacteria,2JIX3@204432|Acidobacteriia	204432|Acidobacteriia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
MMS3_k127_2275655_0	204669.Acid345_0563	3.325e-111	368.0	COG0052@1|root,COG0052@2|Bacteria,3Y3K2@57723|Acidobacteria,2JI0A@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
MMS3_k127_2275655_6	234267.Acid_0907	7.075e-45	166.0	COG0103@1|root,COG0103@2|Bacteria,3Y4IK@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
MMS3_k127_2275655_7	240015.ACP_2944	9.191e-43	162.0	COG0102@1|root,COG0102@2|Bacteria,3Y4U5@57723|Acidobacteria,2JJGG@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
MMS3_k127_2275655_9	397948.Cmaq_1393	2.537e-11	73.0	COG0491@1|root,arCOG00504@2157|Archaea,2XRY0@28889|Crenarchaeota	28889|Crenarchaeota	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_2275655_5	35841.BT1A1_3284	2.211e-51	194.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,1ZBZD@1386|Bacillus	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
MMS3_k127_2276063_0	1123508.JH636439_gene1853	2.152e-140	469.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
MMS3_k127_2276063_1	1123508.JH636448_gene7561	1.202e-08	59.0	COG2421@1|root,COG2421@2|Bacteria,2J06T@203682|Planctomycetes	203682|Planctomycetes	C	acetamidase formamidase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
MMS3_k127_2279108_2	234267.Acid_3617	3.772e-40	155.0	COG4758@1|root,COG4758@2|Bacteria,3Y7Z2@57723|Acidobacteria	57723|Acidobacteria	S	N-terminal domain of toast_rack, DUF2154	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
MMS3_k127_2279108_0	1382359.JIAL01000001_gene1365	8.022e-203	640.0	COG2309@1|root,COG2309@2|Bacteria,3Y2Z6@57723|Acidobacteria,2JIPZ@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase, M29 (Aminopeptidase	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
MMS3_k127_2279108_1	234267.Acid_6934	5.093e-140	458.0	COG1132@1|root,COG1132@2|Bacteria,3Y452@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
MMS3_k127_2282851_1	1267534.KB906757_gene1065	4.154e-142	458.0	COG3250@1|root,COG3250@2|Bacteria,3Y455@57723|Acidobacteria,2JHYM@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
MMS3_k127_2282851_0	1097668.BYI23_C003260	4.397e-154	498.0	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2VMA4@28216|Betaproteobacteria,1JZYG@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2285409_8	671143.DAMO_1931	1.844e-18	88.0	COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_2285409_3	443143.GM18_4283	9.692e-72	256.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,43UXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMS3_k127_2285409_0	671143.DAMO_1933	0.0	1255.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMS3_k127_2285409_6	1230457.C476_03743	1.853e-22	110.0	COG0589@1|root,arCOG00449@2157|Archaea,2XVPB@28890|Euryarchaeota,23SHQ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2285409_7	234267.Acid_4150	1.508e-20	93.0	COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
MMS3_k127_2285409_1	234267.Acid_5526	2.253e-139	458.0	COG1032@1|root,COG1032@2|Bacteria,3Y2NI@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
MMS3_k127_2285409_9	452637.Oter_0385	5.509e-10	65.0	COG0810@1|root,COG0810@2|Bacteria,46WNS@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMS3_k127_2285409_10	344747.PM8797T_15566	3.341e-06	55.0	COG2204@1|root,COG2204@2|Bacteria,2IY95@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_2285409_5	1122604.JONR01000031_gene1253	2.132e-63	234.0	COG0477@1|root,COG2814@2|Bacteria,1QYFY@1224|Proteobacteria	1224|Proteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2285409_4	886293.Sinac_7535	5.51e-71	253.0	COG5434@1|root,COG5434@2|Bacteria,2IX4K@203682|Planctomycetes	2|Bacteria	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
MMS3_k127_2288473_0	1267535.KB906767_gene3933	4.761e-154	499.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria,2JI4A@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_2288473_1	1120949.KB903298_gene5782	1.854e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4DD5F@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
MMS3_k127_2288473_2	1267535.KB906767_gene3114	8.616e-07	54.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
MMS3_k127_2289130_1	204669.Acid345_0972	6.556e-83	281.0	COG2197@1|root,COG2197@2|Bacteria,3Y2WY@57723|Acidobacteria,2JIR0@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_2289130_0	204669.Acid345_0973	6.841e-138	459.0	COG4585@1|root,COG4585@2|Bacteria,3Y8CF@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
MMS3_k127_2292859_4	208444.JNYY01000010_gene2718	1.05e-05	53.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4DYCY@85010|Pseudonocardiales	201174|Actinobacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
MMS3_k127_2292859_0	936455.KI421499_gene4490	1.403e-143	468.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2TRBF@28211|Alphaproteobacteria,3JXPV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	benK	-	-	ko:K05548,ko:K08178,ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.12,2.A.1.15	-	-	MFS_1,MFS_4,Sugar_tr
MMS3_k127_2292859_1	1340493.JNIF01000003_gene2611	2.999e-86	294.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_2292859_2	234267.Acid_6971	5.5e-85	292.0	COG2930@1|root,COG2930@2|Bacteria,3Y4GG@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
MMS3_k127_2292859_3	234267.Acid_7653	4.34e-56	198.0	COG4101@1|root,COG4101@2|Bacteria,3Y7NQ@57723|Acidobacteria	57723|Acidobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_2293750_0	643473.KB235930_gene4348	4.216e-129	425.0	COG2124@1|root,COG2124@2|Bacteria,1G3SX@1117|Cyanobacteria,1HMP2@1161|Nostocales	1117|Cyanobacteria	Q	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2293750_2	887062.HGR_14759	4.995e-06	55.0	COG0745@1|root,COG0745@2|Bacteria	887062.HGR_14759|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2293750_1	344747.PM8797T_06847	4.712e-83	293.0	COG0657@1|root,COG3458@1|root,COG0657@2|Bacteria,COG3458@2|Bacteria,2J1TC@203682|Planctomycetes	203682|Planctomycetes	Q	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2295420_4	1028800.RG540_CH26290	1.497e-19	99.0	2EFHI@1|root,339A3@2|Bacteria,1P7AX@1224|Proteobacteria	1224|Proteobacteria	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C70
MMS3_k127_2295420_3	1173029.JH980292_gene3212	1.244e-20	100.0	COG2253@1|root,COG2253@2|Bacteria,1G952@1117|Cyanobacteria,1HGRG@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
MMS3_k127_2295420_2	1340493.JNIF01000003_gene3403	2.806e-31	132.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	AbiEi_4
MMS3_k127_2295420_0	240015.ACP_3302	1.835e-130	428.0	COG2211@1|root,COG2211@2|Bacteria,3Y75A@57723|Acidobacteria,2JKQE@204432|Acidobacteriia	204432|Acidobacteriia	G	Major facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	-
MMS3_k127_2295420_1	1267535.KB906767_gene4240	5.258e-112	376.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Trans_reg_C
MMS3_k127_2295975_6	335543.Sfum_0922	9.554e-24	107.0	COG2890@1|root,COG2890@2|Bacteria,1QUYS@1224|Proteobacteria,42UV8@68525|delta/epsilon subdivisions,2WQQU@28221|Deltaproteobacteria,2MRUR@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_2295975_0	204669.Acid345_2524	2.117e-182	586.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,3Y3QY@57723|Acidobacteria,2JHPJ@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
MMS3_k127_2295975_3	1237149.C900_04939	1.168e-89	314.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_2295975_4	330214.NIDE3730	5.548e-77	276.0	COG0612@1|root,COG0612@2|Bacteria,3J0I5@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_2295975_5	1267533.KB906733_gene3226	8.522e-44	173.0	COG1266@1|root,COG1266@2|Bacteria,3Y6E3@57723|Acidobacteria	57723|Acidobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
MMS3_k127_2295975_2	240015.ACP_0790	5.008e-102	346.0	COG1686@1|root,COG1686@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11,SPOR
MMS3_k127_2295975_1	316067.Geob_1755	3.599e-141	462.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2X6YF@28221|Deltaproteobacteria,43TQ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1,cNMP_binding
MMS3_k127_2298287_6	204669.Acid345_1473	1.991e-70	251.0	COG4796@1|root,COG4796@2|Bacteria,3Y98D@57723|Acidobacteria	57723|Acidobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
MMS3_k127_2298287_4	234267.Acid_7433	2.458e-91	314.0	COG0006@1|root,COG0006@2|Bacteria,3Y3IN@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_2298287_8	1121430.JMLG01000003_gene572	4.456e-37	147.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,260JY@186807|Peptococcaceae	186801|Clostridia	CI	Acetyl-CoA carboxylase, biotin carboxyl carrier protein	pycB	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
MMS3_k127_2298287_1	391600.ABRU01000025_gene1255	2.418e-165	531.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2KFCN@204458|Caulobacterales	204458|Caulobacterales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
MMS3_k127_2298287_7	204669.Acid345_3286	3.988e-43	168.0	COG0352@1|root,COG0352@2|Bacteria,3Y4Y5@57723|Acidobacteria,2JJM3@204432|Acidobacteriia	204432|Acidobacteriia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
MMS3_k127_2298287_2	234267.Acid_4943	1.507e-164	530.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMS3_k127_2298287_0	379066.GAU_1432	3.628e-168	541.0	COG0531@1|root,COG0531@2|Bacteria,1ZSUB@142182|Gemmatimonadetes	2|Bacteria	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMS3_k127_2298287_3	1267533.KB906736_gene1274	3.542e-106	370.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,3Y2P9@57723|Acidobacteria,2JIVP@204432|Acidobacteriia	204432|Acidobacteriia	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
MMS3_k127_2298287_5	204669.Acid345_3283	1.525e-82	287.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,3Y4K4@57723|Acidobacteria,2JMIM@204432|Acidobacteriia	204432|Acidobacteriia	P	TrkA-C domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
MMS3_k127_2298287_9	234267.Acid_2158	9.117e-36	141.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,3Y3XN@57723|Acidobacteria	57723|Acidobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
MMS3_k127_2301358_3	222534.KB893783_gene5328	3.938e-06	59.0	2DXGG@1|root,32V3F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2301358_1	56107.Cylst_5960	1.347e-45	180.0	COG0438@1|root,COG0438@2|Bacteria,1G0EH@1117|Cyanobacteria,1HKD7@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2301358_0	326424.FRAAL2051	2.032e-51	192.0	COG0702@1|root,COG2265@1|root,COG0702@2|Bacteria,COG2265@2|Bacteria,2IQ0Z@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Methyltransf_21,NAD_binding_10
MMS3_k127_2301358_2	1217718.ALOU01000069_gene4838	1.945e-06	55.0	COG0438@1|root,COG0438@2|Bacteria,1R8CX@1224|Proteobacteria,2WF7X@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2304890_1	867903.ThesuDRAFT_02082	8.785e-49	179.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3WDHI@538999|Clostridiales incertae sedis	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_2304890_3	1278073.MYSTI_06620	3.969e-42	161.0	COG0251@1|root,COG0251@2|Bacteria,1RES6@1224|Proteobacteria,435VN@68525|delta/epsilon subdivisions,2X0B9@28221|Deltaproteobacteria,2Z1FV@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
MMS3_k127_2304890_0	234267.Acid_2796	1.397e-116	396.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
MMS3_k127_2304890_4	756272.Plabr_1950	1.605e-13	83.0	COG1413@1|root,COG3391@1|root,COG1413@2|Bacteria,COG3391@2|Bacteria,2IXTT@203682|Planctomycetes	203682|Planctomycetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
MMS3_k127_2304890_2	596151.DesfrDRAFT_2607	1.663e-46	177.0	COG1011@1|root,COG1011@2|Bacteria,1Q2A2@1224|Proteobacteria,42WDV@68525|delta/epsilon subdivisions,2WRQS@28221|Deltaproteobacteria,2MA67@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMS3_k127_2307820_0	401053.AciPR4_4204	1.897e-249	784.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria,2JHV7@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
MMS3_k127_2307820_2	278963.ATWD01000001_gene2081	4.338e-52	192.0	COG0290@1|root,COG0290@2|Bacteria,3Y3VP@57723|Acidobacteria,2JIGK@204432|Acidobacteriia	204432|Acidobacteriia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
MMS3_k127_2307820_4	1267533.KB906734_gene4197	1.811e-14	75.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
MMS3_k127_2307820_3	1382359.JIAL01000001_gene595	3.443e-34	136.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
MMS3_k127_2307820_1	1047013.AQSP01000119_gene1303	2.738e-80	278.0	COG0016@1|root,COG0016@2|Bacteria,2NNNT@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
MMS3_k127_2313811_6	1267533.KB906735_gene4570	5.233e-43	163.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria,2JI4A@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_2313811_3	240015.ACP_3370	5.571e-76	274.0	COG1807@1|root,COG1807@2|Bacteria,3Y2UV@57723|Acidobacteria,2JIS6@204432|Acidobacteriia	204432|Acidobacteriia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_2313811_1	1123242.JH636434_gene4913	3.718e-150	486.0	COG0667@1|root,COG0667@2|Bacteria,2IYAG@203682|Planctomycetes	203682|Planctomycetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_2313811_4	1267535.KB906767_gene3216	2.09e-46	177.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
MMS3_k127_2313811_5	234267.Acid_4408	4.288e-43	164.0	COG0394@1|root,COG0394@2|Bacteria,3Y5NY@57723|Acidobacteria	57723|Acidobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
MMS3_k127_2313811_0	1033743.CAES01000022_gene1569	5.959e-164	523.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,4HC8A@91061|Bacilli,26SFW@186822|Paenibacillaceae	91061|Bacilli	P	Sodium Bile acid symporter family	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
MMS3_k127_2313811_2	648757.Rvan_3533	6.988e-121	393.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
MMS3_k127_2326340_1	247490.KSU1_C0714	5.565e-90	328.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
MMS3_k127_2326340_2	105425.BBPL01000058_gene4984	2.51e-26	127.0	COG1874@1|root,COG5434@1|root,COG1874@2|Bacteria,COG5434@2|Bacteria,2GKCR@201174|Actinobacteria,2NGMR@228398|Streptacidiphilus	201174|Actinobacteria	GM	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Beta_helix,CARDB,DUF1573,F5_F8_type_C,Pectate_lyase_3
MMS3_k127_2326340_0	204669.Acid345_1469	2.255e-113	376.0	COG4972@1|root,COG4972@2|Bacteria,3Y804@57723|Acidobacteria	57723|Acidobacteria	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
MMS3_k127_2326340_3	204669.Acid345_1470	1.582e-13	78.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
MMS3_k127_2326340_4	314292.VAS14_21377	1.246e-09	66.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1XVAF@135623|Vibrionales	135623|Vibrionales	NU	assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
MMS3_k127_2327196_6	518766.Rmar_0669	6.877e-47	178.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1FJ16@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
MMS3_k127_2327196_4	1449126.JQKL01000011_gene3570	8.093e-64	231.0	COG0329@1|root,COG0329@2|Bacteria,1TPSG@1239|Firmicutes,24H6N@186801|Clostridia,26BBJ@186813|unclassified Clostridiales	186801|Clostridia	EM	Dihydrodipicolinate synthetase family	-	-	4.1.3.16	ko:K18123	ko00330,ko00630,ko01100,map00330,map00630,map01100	-	R00470,R00471	RC00307,RC00308	ko00000,ko00001,ko01000	-	-	-	DHDPS
MMS3_k127_2327196_0	1267535.KB906767_gene717	0.0	1398.0	COG0458@1|root,COG0458@2|Bacteria,3Y3GG@57723|Acidobacteria,2JIJZ@204432|Acidobacteriia	204432|Acidobacteriia	F	TIGRFAM carbamoyl-phosphate synthase, large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
MMS3_k127_2327196_1	1382359.JIAL01000001_gene2523	7.285e-170	540.0	COG0505@1|root,COG0505@2|Bacteria,3Y31Y@57723|Acidobacteria,2JIB8@204432|Acidobacteriia	204432|Acidobacteriia	F	TIGRFAM Carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
MMS3_k127_2327196_5	1382359.JIAL01000001_gene451	2.083e-54	198.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria,2JJ4I@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
MMS3_k127_2327196_3	237368.SCABRO_03425	2.866e-64	228.0	COG0463@1|root,COG0463@2|Bacteria,2IZV0@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_2327196_8	1283300.ATXB01000001_gene2443	5.404e-12	75.0	COG3637@1|root,COG3637@2|Bacteria,1NHDI@1224|Proteobacteria	1224|Proteobacteria	M	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
MMS3_k127_2327196_2	234267.Acid_0734	4.456e-125	411.0	COG0484@1|root,COG0484@2|Bacteria,3Y33I@57723|Acidobacteria	57723|Acidobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS3_k127_2327196_7	234267.Acid_0733	4.856e-36	144.0	COG0576@1|root,COG0576@2|Bacteria,3Y54K@57723|Acidobacteria	57723|Acidobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
MMS3_k127_2341660_1	240015.ACP_2653	1.485e-65	237.0	COG1957@1|root,COG1957@2|Bacteria,3Y97V@57723|Acidobacteria,2JMFV@204432|Acidobacteriia	204432|Acidobacteriia	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
MMS3_k127_2341660_0	671143.DAMO_0568	1.052e-220	703.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_2356167_2	1340493.JNIF01000003_gene4121	4.696e-28	117.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2356167_1	1267535.KB906767_gene4227	4.635e-31	140.0	COG3485@1|root,COG3485@2|Bacteria,3Y44E@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_2356167_0	204669.Acid345_3357	1.086e-125	417.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
MMS3_k127_2367330_7	1382359.JIAL01000001_gene1340	3.82e-07	58.0	COG1520@1|root,COG1520@2|Bacteria,3Y3UP@57723|Acidobacteria	57723|Acidobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
MMS3_k127_2367330_4	204669.Acid345_0088	4.528e-41	158.0	COG0328@1|root,COG0328@2|Bacteria,3Y4EY@57723|Acidobacteria,2JJ1U@204432|Acidobacteriia	204432|Acidobacteriia	L	Reverse transcriptase-like	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
MMS3_k127_2367330_6	1232437.KL661986_gene3637	1.447e-25	116.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WKVG@28221|Deltaproteobacteria,2MJ11@213118|Desulfobacterales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
MMS3_k127_2367330_5	1089550.ATTH01000001_gene1029	2.896e-37	147.0	COG1437@1|root,COG1437@2|Bacteria,4NQQK@976|Bacteroidetes	976|Bacteroidetes	F	CYTH domain	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
MMS3_k127_2367330_0	1382306.JNIM01000001_gene3339	2.681e-258	809.0	COG0129@1|root,COG0129@2|Bacteria,2G67Z@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
MMS3_k127_2367330_3	204669.Acid345_1284	1.817e-42	158.0	COG1695@1|root,COG1695@2|Bacteria,3Y5C5@57723|Acidobacteria,2JNCX@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_2367330_1	251221.35211765	1.891e-172	574.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_2367330_2	1242864.D187_005861	2.522e-85	289.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YVB7@29|Myxococcales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_2372039_1	234267.Acid_7670	3.458e-66	236.0	COG0115@1|root,COG0115@2|Bacteria,3Y6HY@57723|Acidobacteria	57723|Acidobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_2372039_3	404589.Anae109_2317	2.032e-23	111.0	COG0622@1|root,COG0622@2|Bacteria,1N8BH@1224|Proteobacteria,43BGF@68525|delta/epsilon subdivisions,2X6UQ@28221|Deltaproteobacteria,2Z0CD@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
MMS3_k127_2372039_0	429009.Adeg_0526	9.187e-138	452.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMS3_k127_2372039_2	309807.SRU_1233	2.15e-35	143.0	COG0665@1|root,COG0665@2|Bacteria,4PEB4@976|Bacteroidetes,1FIQR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_239494_1	1499967.BAYZ01000147_gene694	1.311e-73	259.0	COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria	2|Bacteria	H	Flavin containing amine oxidoreductase	-	-	1.3.3.15,1.3.3.4,5.4.99.9	ko:K00231,ko:K01854	ko00052,ko00520,ko00860,ko01100,ko01110,map00052,map00520,map00860,map01100,map01110	M00121	R00505,R03222,R04178,R09009	RC00317,RC00885,RC02396	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Glyco_trans_1_4,NAD_binding_8
MMS3_k127_239494_2	1307436.PBF_07953	3.7e-72	253.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus	91061|Bacilli	M	UTP-glucose-1-phosphate uridylyltransferase	yngB	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_239494_0	1408164.MOLA814_00704	4.425e-81	286.0	COG0279@1|root,COG0279@2|Bacteria	2|Bacteria	G	D-glycero-D-manno-heptose 7-phosphate metabolic process	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
MMS3_k127_239494_3	446466.Cfla_3602	5.711e-37	155.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83,5.3.1.28	ko:K03271,ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05645,R05647,R09768,R09769,R09771	RC00017,RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,NTP_transferase,PNK3P
MMS3_k127_2404213_7	1267535.KB906767_gene1432	6.107e-06	49.0	COG2835@1|root,COG2835@2|Bacteria,3Y8VE@57723|Acidobacteria	57723|Acidobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
MMS3_k127_2404213_0	517418.Ctha_0907	8.269e-151	511.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
MMS3_k127_2404213_1	575540.Isop_1915	1.862e-97	332.0	COG0624@1|root,COG0624@2|Bacteria,2IZ39@203682|Planctomycetes	203682|Planctomycetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_2404213_4	1266908.AQPB01000012_gene1545	2.809e-38	145.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales	135613|Chromatiales	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
MMS3_k127_2404213_3	234267.Acid_7407	2.25e-40	160.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,3Y4FC@57723|Acidobacteria	57723|Acidobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
MMS3_k127_2404213_5	1267535.KB906767_gene394	8.582e-36	148.0	COG0705@1|root,COG0705@2|Bacteria,3Y4GU@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
MMS3_k127_2404213_2	1120973.AQXL01000133_gene1794	5.729e-86	289.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli,27907@186823|Alicyclobacillaceae	91061|Bacilli	E	Aconitase C-terminal domain	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
MMS3_k127_2404213_6	530564.Psta_3946	3.204e-10	60.0	COG0065@1|root,COG0065@2|Bacteria,2IXHR@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
MMS3_k127_2412060_2	1382306.JNIM01000001_gene3887	2.357e-100	334.0	COG1028@1|root,COG1028@2|Bacteria	1382306.JNIM01000001_gene3887|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2412060_12	448385.sce0302	1.567e-07	63.0	COG5549@1|root,COG5549@2|Bacteria,1PC02@1224|Proteobacteria,433UB@68525|delta/epsilon subdivisions,2X3H4@28221|Deltaproteobacteria,2YW2B@29|Myxococcales	28221|Deltaproteobacteria	O	Matrixin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
MMS3_k127_2412060_9	1297742.A176_06884	3.305e-11	73.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2412060_13	204669.Acid345_0451	4.377e-07	61.0	COG5492@1|root,COG5492@2|Bacteria,3Y7YW@57723|Acidobacteria,2JN4C@204432|Acidobacteriia	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Polysacc_lyase,SLH
MMS3_k127_2412060_7	204669.Acid345_1580	4.797e-29	128.0	2DRPK@1|root,32URD@2|Bacteria,3Y4UQ@57723|Acidobacteria,2JJGZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2412060_10	204669.Acid345_1577	2.135e-08	63.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria,2JJG9@204432|Acidobacteriia	204432|Acidobacteriia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
MMS3_k127_2412060_8	1198114.AciX9_0946	2e-15	87.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria,2JKII@204432|Acidobacteriia	204432|Acidobacteriia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
MMS3_k127_2412060_1	204669.Acid345_1576	1.098e-229	724.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
MMS3_k127_2412060_3	234267.Acid_0044	6.022e-94	322.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria	57723|Acidobacteria	NU	type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
MMS3_k127_2412060_6	204669.Acid345_1999	4.592e-39	150.0	COG2165@1|root,COG2165@2|Bacteria,3Y4ZX@57723|Acidobacteria,2JJN5@204432|Acidobacteriia	204432|Acidobacteriia	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
MMS3_k127_2412060_5	1267535.KB906767_gene847	9.239e-47	175.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria,2JJB4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
MMS3_k127_2412060_4	1267533.KB906733_gene3613	1.898e-91	323.0	COG4796@1|root,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria,2JHZH@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
MMS3_k127_2412060_11	1166018.FAES_0139	2.713e-08	57.0	COG5466@1|root,COG5466@2|Bacteria,4NVUX@976|Bacteroidetes,47SA9@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
MMS3_k127_2412060_0	1449049.JONW01000005_gene1138	1.49e-297	930.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,2U0Q9@28211|Alphaproteobacteria,2KFEI@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
MMS3_k127_2415421_2	1267533.KB906747_gene19	4.781e-155	492.0	COG1034@1|root,COG1034@2|Bacteria,3Y9EE@57723|Acidobacteria,2JP7T@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
MMS3_k127_2415421_1	1267533.KB906747_gene20	1.452e-220	690.0	COG1894@1|root,COG1894@2|Bacteria,3Y2NM@57723|Acidobacteria,2JI09@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMS3_k127_2415421_3	1267535.KB906767_gene58	7.732e-70	239.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMS3_k127_2415421_0	1267533.KB906747_gene22	3.26e-300	929.0	COG0649@1|root,COG0649@2|Bacteria,3Y3N1@57723|Acidobacteria,2JIDU@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
MMS3_k127_2415421_4	323261.Noc_1126	5.786e-44	161.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMS3_k127_2429700_0	1210884.HG799462_gene8047	1.869e-153	491.0	COG1914@1|root,COG1914@2|Bacteria,2J0SG@203682|Planctomycetes	203682|Planctomycetes	P	Natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
MMS3_k127_2429700_7	861299.J421_4362	8.088e-35	138.0	COG0589@1|root,COG0589@2|Bacteria,1ZTUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2429700_2	3218.PP1S46_300V6.1	7.484e-96	326.0	COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta	35493|Streptophyta	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_2429700_4	204669.Acid345_3529	1.007e-87	297.0	COG1912@1|root,COG1912@2|Bacteria,3Y50E@57723|Acidobacteria,2JMWN@204432|Acidobacteriia	204432|Acidobacteriia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
MMS3_k127_2429700_3	204669.Acid345_3532	1.706e-90	315.0	COG1253@1|root,COG1253@2|Bacteria,3Y2KE@57723|Acidobacteria,2JHJ4@204432|Acidobacteriia	204432|Acidobacteriia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
MMS3_k127_2429700_6	243231.GSU1756	5.386e-51	193.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
MMS3_k127_2429700_1	234267.Acid_4402	1.352e-105	356.0	COG0167@1|root,COG0167@2|Bacteria,3Y2K1@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMS3_k127_2429700_10	1449351.RISW2_15220	3.12e-12	77.0	COG2227@1|root,COG2227@2|Bacteria,1PSNI@1224|Proteobacteria,2TV3H@28211|Alphaproteobacteria,4KK0X@93682|Roseivivax	28211|Alphaproteobacteria	H	3-demethylubiquinone-9 3-methyltransferase	ubiG1	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
MMS3_k127_2429700_5	886293.Sinac_0214	8.183e-69	259.0	COG3119@1|root,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
MMS3_k127_2429700_8	1380356.JNIK01000004_gene175	8.164e-30	127.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,Methyltransf_11,Methyltransf_23
MMS3_k127_2429700_9	1267535.KB906767_gene1575	3.628e-21	95.0	COG2133@1|root,COG2133@2|Bacteria,3Y6R6@57723|Acidobacteria,2JMHE@204432|Acidobacteriia	204432|Acidobacteriia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2443748_5	240015.ACP_2350	2.49e-123	406.0	COG0513@1|root,COG0513@2|Bacteria,3Y2M6@57723|Acidobacteria,2JHVB@204432|Acidobacteriia	204432|Acidobacteriia	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
MMS3_k127_2443748_0	234267.Acid_7693	1.431e-284	885.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
MMS3_k127_2443748_1	1267534.KB906754_gene3783	6.279e-163	519.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
MMS3_k127_2443748_7	69279.BG36_08325	2.326e-77	272.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2TT4K@28211|Alphaproteobacteria,43H3Z@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	GM	biosynthesis protein	capD	-	-	ko:K13013	-	-	-	-	ko00000,ko01005	-	-	-	CoA_binding_3,Polysacc_synt_2
MMS3_k127_2443748_2	1382359.JIAL01000001_gene1313	8.955e-161	514.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	neuC	GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016787,GO:0016798,GO:0044238,GO:0071704,GO:1901576	3.2.1.184,5.1.3.14	ko:K01791,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
MMS3_k127_2443748_3	1382359.JIAL01000001_gene1312	7.199e-133	434.0	COG0399@1|root,COG0399@2|Bacteria,3Y2QT@57723|Acidobacteria,2JKCR@204432|Acidobacteriia	204432|Acidobacteriia	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_2443748_6	1267535.KB906767_gene4255	1.858e-87	294.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria,2JHQM@204432|Acidobacteriia	204432|Acidobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
MMS3_k127_2443748_8	1408254.T458_25850	3.917e-25	107.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26Y4X@186822|Paenibacillaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
MMS3_k127_2443748_4	234267.Acid_3165	5.117e-128	429.0	COG2812@1|root,COG2812@2|Bacteria,3Y3C4@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
MMS3_k127_2443748_9	234267.Acid_1169	2.548e-08	62.0	COG2823@1|root,COG2823@2|Bacteria,3Y7GR@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2445953_0	234267.Acid_2421	6.971e-83	280.0	COG1319@1|root,COG1319@2|Bacteria,3Y3NU@57723|Acidobacteria	57723|Acidobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMS3_k127_2445953_5	1192034.CAP_6379	8.59e-07	55.0	2BHQP@1|root,32BTZ@2|Bacteria,1QA9D@1224|Proteobacteria,434X3@68525|delta/epsilon subdivisions,2X92E@28221|Deltaproteobacteria,2Z1J1@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2445953_1	234267.Acid_2426	3.558e-58	209.0	COG5588@1|root,COG5588@2|Bacteria,3Y7RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
MMS3_k127_2445953_2	234267.Acid_7948	9.324e-29	124.0	2E6AH@1|root,330YD@2|Bacteria,3Y8MQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2445953_3	1267534.KB906754_gene2846	5.211e-21	95.0	COG3391@1|root,COG3391@2|Bacteria,3Y66Q@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2482445_2	204669.Acid345_0444	1.56e-125	411.0	COG1879@1|root,COG1879@2|Bacteria,3Y36B@57723|Acidobacteria,2JHWG@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
MMS3_k127_2482445_0	1267534.KB906757_gene1074	0.0	1078.0	COG1629@1|root,COG1629@2|Bacteria,3Y72I@57723|Acidobacteria,2JKKK@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
MMS3_k127_2482445_1	1267533.KB906735_gene4787	9.769e-147	476.0	COG5520@1|root,COG5520@2|Bacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.46	ko:K01202	ko00600,ko01100,ko04142,map00600,map01100,map04142	-	R03617	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH59	-	Glyco_hydro_59,Glyco_hydro_59M,Laminin_G_3,RicinB_lectin_2,Ricin_B_lectin
MMS3_k127_2547959_13	1267535.KB906767_gene2843	5.644e-05	45.0	COG0004@1|root,COG0004@2|Bacteria,3Y2MU@57723|Acidobacteria,2JJ1F@204432|Acidobacteriia	204432|Acidobacteriia	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMS3_k127_2547959_12	351160.RCIX2687	5.201e-06	55.0	COG0457@1|root,arCOG03038@2157|Archaea	2157|Archaea	KLT	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
MMS3_k127_2547959_6	867903.ThesuDRAFT_02248	1.211e-84	296.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia	186801|Clostridia	P	Transporter, CPA2 family	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
MMS3_k127_2547959_8	1382359.JIAL01000001_gene617	4.121e-45	166.0	COG0347@1|root,COG0347@2|Bacteria,3Y4TF@57723|Acidobacteria,2JJHW@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
MMS3_k127_2547959_5	357808.RoseRS_3609	1.488e-102	343.0	COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
MMS3_k127_2547959_0	211165.AJLN01000042_gene530	2.865e-320	1004.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1JKQM@1189|Stigonemataceae	1117|Cyanobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
MMS3_k127_2547959_9	1123388.AQWU01000072_gene1326	8.864e-34	135.0	COG0517@1|root,COG0517@2|Bacteria,1WK09@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMS3_k127_2547959_11	314230.DSM3645_21362	2.927e-07	57.0	2BRMF@1|root,32KKV@2|Bacteria,2J49V@203682|Planctomycetes	203682|Planctomycetes	S	Winged helix-turn-helix domain (DUF2582)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2582
MMS3_k127_2547959_7	1123250.KB908379_gene1160	5.299e-60	218.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4H272@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
MMS3_k127_2547959_10	330214.NIDE1818	6.825e-26	111.0	COG1977@1|root,COG1977@2|Bacteria,3J0T2@40117|Nitrospirae	40117|Nitrospirae	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS3_k127_2547959_2	247490.KSU1_D0389	1.966e-156	504.0	COG0498@1|root,COG0498@2|Bacteria,2IXWR@203682|Planctomycetes	203682|Planctomycetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_2547959_1	1267535.KB906767_gene581	8.756e-274	854.0	COG2936@1|root,COG2936@2|Bacteria	2|Bacteria	V	dipeptidyl-peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_2547959_4	234267.Acid_2255	4.793e-123	402.0	COG3618@1|root,COG3618@2|Bacteria,3Y4FF@57723|Acidobacteria	57723|Acidobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2565932_1	639030.JHVA01000001_gene810	2.972e-214	679.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
MMS3_k127_2565932_2	682795.AciX8_4253	8.688e-166	536.0	COG3119@1|root,COG3119@2|Bacteria,3Y6DU@57723|Acidobacteria,2JM3W@204432|Acidobacteriia	204432|Acidobacteriia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
MMS3_k127_2565932_0	929713.NIASO_20845	3.47e-272	859.0	COG3250@1|root,COG3250@2|Bacteria,4NHRH@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
MMS3_k127_2565932_6	582402.Hbal_2742	4.384e-06	53.0	COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2VFFD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
MMS3_k127_2565932_7	264198.Reut_B4430	0.0001043	51.0	COG2010@1|root,COG2010@2|Bacteria,1RDVX@1224|Proteobacteria	1224|Proteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
MMS3_k127_2565932_3	269799.Gmet_1812	1.228e-152	496.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
MMS3_k127_2565932_4	269799.Gmet_1811	5.324e-96	319.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,43TY6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMS3_k127_2565932_5	479434.Sthe_2164	1.78e-55	203.0	COG0243@1|root,COG0243@2|Bacteria,2G844@200795|Chloroflexi,27XFA@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
MMS3_k127_2570736_9	240015.ACP_2680	4.326e-47	173.0	COG1028@1|root,COG1028@2|Bacteria,3Y3CD@57723|Acidobacteria,2JHIF@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_2570736_12	269797.Mbar_A3643	3.993e-20	107.0	COG0457@1|root,arCOG05195@1|root,arCOG03038@2157|Archaea,arCOG05195@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAF9@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
MMS3_k127_2570736_10	1123377.AUIV01000015_gene235	1.313e-36	151.0	2F845@1|root,31I6D@2|Bacteria,1QFVM@1224|Proteobacteria,1TD69@1236|Gammaproteobacteria,1XA7M@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2570736_1	243231.GSU1456	6.469e-122	426.0	COG0457@1|root,COG0457@2|Bacteria,1NU49@1224|Proteobacteria,42YQH@68525|delta/epsilon subdivisions,2WU55@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2570736_0	56780.SYN_00856	1.891e-135	446.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,42MRD@68525|delta/epsilon subdivisions,2X5MW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
MMS3_k127_2570736_16	1005048.CFU_2668	0.0001022	55.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2VNIJ@28216|Betaproteobacteria,475WJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
MMS3_k127_2570736_3	204669.Acid345_0799	3.116e-112	381.0	COG0607@1|root,COG1651@1|root,COG3266@1|root,COG4243@1|root,COG0607@2|Bacteria,COG1651@2|Bacteria,COG3266@2|Bacteria,COG4243@2|Bacteria,3Y5CK@57723|Acidobacteria,2JJU9@204432|Acidobacteriia	204432|Acidobacteriia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
MMS3_k127_2570736_6	335543.Sfum_1692	1.805e-82	284.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2WK2V@28221|Deltaproteobacteria,2MRFM@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI,ThiP_synth
MMS3_k127_2570736_14	1267535.KB906767_gene2388	4.177e-15	83.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
MMS3_k127_2570736_13	472759.Nhal_2626	7.538e-18	86.0	2DPU9@1|root,333E7@2|Bacteria,1N6Y7@1224|Proteobacteria,1SW3Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2570736_5	1267535.KB906767_gene5244	2.849e-90	315.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
MMS3_k127_2570736_8	1382359.JIAL01000001_gene804	1.597e-56	207.0	COG1136@1|root,COG1136@2|Bacteria,3Y3JD@57723|Acidobacteria,2JIHH@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2570736_7	240015.ACP_1853	1.951e-58	216.0	COG0577@1|root,COG0577@2|Bacteria,3Y32V@57723|Acidobacteria,2JI59@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_2570736_11	1382359.JIAL01000001_gene2643	8.388e-24	107.0	COG1396@1|root,COG1396@2|Bacteria,3Y52W@57723|Acidobacteria,2JJE1@204432|Acidobacteriia	204432|Acidobacteriia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMS3_k127_2570736_2	4432.XP_010252517.1	1.536e-120	394.0	COG0458@1|root,KOG0370@2759|Eukaryota,37MJ1@33090|Viridiplantae,3GGQ1@35493|Streptophyta	35493|Streptophyta	EF	Belongs to the ATCase OTCase family	PYRB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009267,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009987,GO:0009991,GO:0016036,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0034654,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMS3_k127_2570736_4	204669.Acid345_2498	1.056e-101	344.0	COG3437@1|root,COG3437@2|Bacteria,3Y2TI@57723|Acidobacteria,2JHKC@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
MMS3_k127_2570736_15	435591.BDI_3207	1.438e-14	79.0	COG0535@1|root,COG0535@2|Bacteria,4PA9R@976|Bacteroidetes,2FWDR@200643|Bacteroidia	976|Bacteroidetes	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
MMS3_k127_2616284_1	1267535.KB906767_gene2175	8.426e-141	463.0	COG2303@1|root,COG2303@2|Bacteria	1267535.KB906767_gene2175|-	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2616284_0	204669.Acid345_0944	1.381e-265	841.0	COG3291@1|root,COG3345@1|root,COG3291@2|Bacteria,COG3345@2|Bacteria,3Y3KH@57723|Acidobacteria,2JIU6@204432|Acidobacteriia	204432|Acidobacteriia	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase,PKD
MMS3_k127_2616284_2	234267.Acid_4914	3.873e-133	439.0	COG0531@1|root,COG0531@2|Bacteria,3Y3Z8@57723|Acidobacteria	2|Bacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
MMS3_k127_2616284_3	760568.Desku_1534	1.301e-66	242.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,260FM@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
MMS3_k127_262848_1	926550.CLDAP_05980	2.786e-65	233.0	COG3842@1|root,COG3842@2|Bacteria,2G6S3@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE_2
MMS3_k127_262848_0	251221.35214857	2.843e-66	240.0	COG4149@1|root,COG4149@2|Bacteria,1G08P@1117|Cyanobacteria	1117|Cyanobacteria	P	molybdate ABC transporter, permease protein	modB	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1
MMS3_k127_262848_2	880072.Desac_1060	4.071e-61	221.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42MZE@68525|delta/epsilon subdivisions,2WKJB@28221|Deltaproteobacteria,2MQEW@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iAF987.Gmet_0512	SBP_bac_11
MMS3_k127_262848_5	240015.ACP_0227	1.599e-38	149.0	COG3585@1|root,COG3585@2|Bacteria,3Y50T@57723|Acidobacteria,2JJMJ@204432|Acidobacteriia	204432|Acidobacteriia	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,TOBE
MMS3_k127_262848_3	876269.ARWA01000001_gene502	2.489e-59	208.0	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,2U0S6@28211|Alphaproteobacteria,3NCGV@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
MMS3_k127_262848_4	1267535.KB906767_gene5023	1.585e-56	200.0	COG3644@1|root,COG3644@2|Bacteria	2|Bacteria	M	Uncharacterized protein conserved in bacteria (DUF2239)	-	-	-	ko:K09965	-	-	-	-	ko00000	-	-	-	DUF2239
MMS3_k127_2672_4	1144275.COCOR_03742	2.502e-19	88.0	COG0667@1|root,COG0667@2|Bacteria,1R77F@1224|Proteobacteria,42Y4Z@68525|delta/epsilon subdivisions,2WTTZ@28221|Deltaproteobacteria,2YYIM@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_2672_5	1123368.AUIS01000003_gene1732	1.604e-11	72.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,2NCVA@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS3_k127_2672_2	697303.Thewi_1772	2.274e-46	177.0	COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,24DU6@186801|Clostridia,42G65@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM alpha beta hydrolase	aroD	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
MMS3_k127_2672_1	1191523.MROS_1008	2.113e-49	185.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
MMS3_k127_2672_3	1191523.MROS_1007	2.489e-28	133.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2672_0	1191523.MROS_1006	3.81e-253	801.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	ybaT	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009268,GO:0009628,GO:0010035,GO:0010038,GO:0016020,GO:0042221,GO:0044464,GO:0046688,GO:0050896,GO:0071944,GO:0097501,GO:1990169	-	ko:K03322,ko:K07076,ko:K09944,ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13,2.A.55.2.6,2.A.55.3	-	-	AA_permease_2,Usp
MMS3_k127_2720452_6	240015.ACP_0485	1.046e-16	83.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria,2JJAP@204432|Acidobacteriia	204432|Acidobacteriia	CO	Glutathione peroxidase	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
MMS3_k127_2720452_3	234267.Acid_0471	1.822e-35	136.0	COG1193@1|root,COG1193@2|Bacteria,3Y8PZ@57723|Acidobacteria	57723|Acidobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
MMS3_k127_2720452_2	926550.CLDAP_30490	2.258e-60	214.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
MMS3_k127_2720452_5	867845.KI911784_gene3184	3.431e-24	104.0	COG0425@1|root,COG0425@2|Bacteria,2G7DF@200795|Chloroflexi,377DX@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
MMS3_k127_2720452_0	644966.Tmar_0252	8.136e-136	443.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,25CRT@186801|Clostridia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
MMS3_k127_2720452_7	686340.Metal_2588	6.421e-15	78.0	2C6B2@1|root,335GA@2|Bacteria,1NG8G@1224|Proteobacteria,1SHZ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2720452_4	686340.Metal_2587	4.19e-28	115.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,1SESI@1236|Gammaproteobacteria,1XGQR@135618|Methylococcales	135618|Methylococcales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
MMS3_k127_2720452_1	1163408.UU9_01814	2.001e-68	235.0	COG4760@1|root,COG4760@2|Bacteria,1REUF@1224|Proteobacteria,1T1EH@1236|Gammaproteobacteria,1XD49@135614|Xanthomonadales	135614|Xanthomonadales	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
MMS3_k127_2721506_2	289376.THEYE_A1750	7.709e-92	307.0	COG1690@1|root,COG1690@2|Bacteria,3J0X0@40117|Nitrospirae	40117|Nitrospirae	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
MMS3_k127_2721506_6	1340493.JNIF01000004_gene559	5.791e-47	175.0	COG2193@1|root,COG2193@2|Bacteria,3Y56Z@57723|Acidobacteria	57723|Acidobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
MMS3_k127_2721506_8	1242864.D187_008636	8.336e-05	54.0	COG4191@1|root,COG4191@2|Bacteria,1NQWQ@1224|Proteobacteria,42TV1@68525|delta/epsilon subdivisions,2WVT9@28221|Deltaproteobacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HDOD,PAS_4
MMS3_k127_2721506_7	234267.Acid_4337	1.077e-19	93.0	COG1983@1|root,COG1983@2|Bacteria,3Y5HA@57723|Acidobacteria	57723|Acidobacteria	KT	Phage shock protein C, PspC	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC,zinc_ribbon_2
MMS3_k127_2721506_1	1047013.AQSP01000125_gene2615	5.198e-129	426.0	COG2252@1|root,COG2252@2|Bacteria,2NNZ2@2323|unclassified Bacteria	2|Bacteria	S	Permease family	pbuG	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	iECH74115_1262.ECH74115_5145,iECOK1_1307.ECOK1_4117,iECSP_1301.ECSP_4762,iECUMN_1333.ECUMN_4191,iECs_1301.ECs4651,iG2583_1286.G2583_4505,iJO1366.b3714,iUTI89_1310.UTI89_C4220,iY75_1357.Y75_RS18500,iYO844.BSU06370,iZ_1308.Z5209	Xan_ur_permease
MMS3_k127_2721506_0	1124780.ANNU01000044_gene487	3.026e-136	447.0	COG1063@1|root,COG1063@2|Bacteria,4P3W3@976|Bacteroidetes	976|Bacteroidetes	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
MMS3_k127_2721506_3	639030.JHVA01000001_gene635	7.265e-80	278.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria,2JI98@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
MMS3_k127_2721506_5	1382359.JIAL01000001_gene880	2.111e-60	212.0	COG0782@1|root,COG0782@2|Bacteria,3Y49X@57723|Acidobacteria,2JJ1A@204432|Acidobacteriia	204432|Acidobacteriia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
MMS3_k127_2721506_4	204669.Acid345_4380	3.617e-72	274.0	COG0457@1|root,COG2956@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,3Y89N@57723|Acidobacteria	57723|Acidobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
MMS3_k127_2721520_5	682795.AciX8_3425	1.078e-19	91.0	COG1629@1|root,COG1629@2|Bacteria,3Y6YE@57723|Acidobacteria,2JM5Z@204432|Acidobacteriia	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_2721520_0	1120950.KB892744_gene2734	1.664e-153	504.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
MMS3_k127_2721520_4	761193.Runsl_1916	7.807e-25	121.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	dexB	-	2.4.1.7,3.2.1.20,3.2.1.51,3.2.1.70,3.2.1.93,3.2.1.97	ko:K00690,ko:K01187,ko:K01206,ko:K01215,ko:K01226,ko:K17624	ko00052,ko00500,ko00511,ko01100,map00052,map00500,map00511,map01100	-	R00028,R00801,R00802,R00803,R00837,R06087,R06088,R06113	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000,ko04147	-	GH101,GH13,GH29,GH31	-	Alpha-amylase,Alpha_L_fucos,CBM_35,F5_F8_type_C,NPCBM_assoc,SLH
MMS3_k127_2721520_2	749414.SBI_01309	2.121e-101	342.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_2721520_1	1382304.JNIL01000001_gene2460	7.845e-104	344.0	COG3618@1|root,COG3618@2|Bacteria,1URZE@1239|Firmicutes,4HAYX@91061|Bacilli	91061|Bacilli	S	amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
MMS3_k127_2721520_3	1123508.JH636441_gene3473	4.456e-78	272.0	COG0673@1|root,COG0673@2|Bacteria,2J1RX@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_2721520_6	1158292.JPOE01000002_gene2056	4.474e-13	75.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
MMS3_k127_2722282_0	706587.Desti_1443	1.836e-245	764.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,42PSJ@68525|delta/epsilon subdivisions,2WJDD@28221|Deltaproteobacteria,2MQTR@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
MMS3_k127_2722282_2	349161.Dred_0636	1.439e-67	232.0	COG1146@1|root,COG1146@2|Bacteria,1V59C@1239|Firmicutes,24J64@186801|Clostridia,261U8@186807|Peptococcaceae	186801|Clostridia	C	reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_7,Fer4_9
MMS3_k127_2722282_1	706587.Desti_1640	2.207e-125	419.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
MMS3_k127_2722282_3	204669.Acid345_2486	3.393e-50	188.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2722282_4	1541065.JRFE01000024_gene886	1.432e-07	56.0	COG3829@1|root,COG3920@1|root,COG3829@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HATPase_c_2,H_kinase_N,HisKA,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_9
MMS3_k127_2725042_2	1267535.KB906767_gene2166	1.13e-33	132.0	COG1609@1|root,COG1609@2|Bacteria,3Y49N@57723|Acidobacteria,2JKAT@204432|Acidobacteriia	204432|Acidobacteriia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
MMS3_k127_2725042_0	240015.ACP_1143	6.621e-311	968.0	COG3534@1|root,COG3534@2|Bacteria,3Y2MY@57723|Acidobacteria,2JKIM@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	-
MMS3_k127_2725042_1	204669.Acid345_0898	2.082e-220	708.0	COG1501@1|root,COG1501@2|Bacteria,3Y4C8@57723|Acidobacteria,2JKE9@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of unknown function (DUF4968)	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
MMS3_k127_2725042_3	204669.Acid345_3246	5.36e-17	81.0	COG1472@1|root,COG1472@2|Bacteria,3Y3H7@57723|Acidobacteria,2JKHJ@204432|Acidobacteriia	204432|Acidobacteriia	G	PA14 domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
MMS3_k127_2727725_2	1382359.JIAL01000001_gene1014	3.689e-111	368.0	COG0038@1|root,COG0038@2|Bacteria,3Y2G4@57723|Acidobacteria,2JIJC@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
MMS3_k127_2727725_3	1267533.KB906735_gene4555	1.236e-39	163.0	COG0457@1|root,COG0457@2|Bacteria,3Y7BQ@57723|Acidobacteria,2JMD5@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
MMS3_k127_2727725_1	240015.ACP_0460	2.193e-174	564.0	COG0038@1|root,COG0038@2|Bacteria,3Y7TT@57723|Acidobacteria,2JMYW@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
MMS3_k127_2727725_4	1408473.JHXO01000007_gene928	6.686e-30	127.0	COG4122@1|root,COG4122@2|Bacteria,4NNYP@976|Bacteroidetes	976|Bacteroidetes	M	tRNA methyltransferase complex GCD14 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
MMS3_k127_2727725_5	88036.EFJ09839	5.975e-27	116.0	COG2453@1|root,KOG1716@2759|Eukaryota,37JIZ@33090|Viridiplantae,3GE9F@35493|Streptophyta	35493|Streptophyta	V	Phosphoglucan phosphatase LSF2	-	GO:0000272,GO:0001871,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009507,GO:0009536,GO:0009987,GO:0016052,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0030246,GO:0030247,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046838,GO:0050308,GO:0071704,GO:1901575,GO:2001070	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	DSPc
MMS3_k127_2727725_0	1267533.KB906733_gene3579	0.0	1021.0	COG0466@1|root,COG0466@2|Bacteria,3Y2QB@57723|Acidobacteria,2JHMJ@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMS3_k127_2736849_8	1267535.KB906767_gene4232	2.17e-09	58.0	COG1082@1|root,COG1082@2|Bacteria,3Y7IK@57723|Acidobacteria,2JMV7@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_2736849_4	1267535.KB906767_gene4233	5.753e-140	452.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
MMS3_k127_2736849_0	1267535.KB906767_gene4234	2.905e-209	661.0	COG0673@1|root,COG0673@2|Bacteria,3Y6RB@57723|Acidobacteria,2JKWU@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_2736849_3	204669.Acid345_0343	2.256e-159	508.0	COG1085@1|root,COG1085@2|Bacteria,3Y41K@57723|Acidobacteria,2JMKJ@204432|Acidobacteriia	204432|Acidobacteriia	C	Domain of unknown function (DUF4921)	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C
MMS3_k127_2736849_7	204669.Acid345_3985	4.393e-19	93.0	COG0792@1|root,COG0792@2|Bacteria,3Y56J@57723|Acidobacteria,2JJU6@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
MMS3_k127_2736849_2	1382359.JIAL01000001_gene464	2.535e-172	551.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_2736849_1	1340493.JNIF01000003_gene1856	4.97e-176	565.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
MMS3_k127_2736849_5	204669.Acid345_3908	3.217e-91	307.0	COG1349@1|root,COG1349@2|Bacteria,3Y3E1@57723|Acidobacteria,2JHXF@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator, DeoR	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
MMS3_k127_2736849_6	1210884.HG799466_gene12661	3.926e-23	100.0	COG4191@1|root,COG4191@2|Bacteria	1210884.HG799466_gene12661|-	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2738851_0	1123023.JIAI01000001_gene6305	1.4e-121	402.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_25
MMS3_k127_2738851_3	118163.Ple7327_3142	2.532e-55	202.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,3VN4P@52604|Pleurocapsales	1117|Cyanobacteria	G	Raf kinase inhibitor-like protein, YbhB YbcL family	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
MMS3_k127_2738851_5	401053.AciPR4_1224	7.42e-27	127.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,3Y310@57723|Acidobacteria,2JI18@204432|Acidobacteriia	57723|Acidobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMS3_k127_2738851_7	323259.Mhun_3001	0.0004058	53.0	arCOG03264@1|root,arCOG03264@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
MMS3_k127_2738851_4	204669.Acid345_1569	8.787e-30	126.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
MMS3_k127_2738851_1	1267533.KB906733_gene3549	1.326e-115	377.0	COG0450@1|root,COG0450@2|Bacteria,3Y444@57723|Acidobacteria,2JIZK@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
MMS3_k127_2738851_6	1289387.AUKW01000004_gene1542	2.998e-13	83.0	COG3525@1|root,COG3525@2|Bacteria,2GK90@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase family 20, catalytic	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
MMS3_k127_2741996_3	1183438.GKIL_2797	5.687e-15	84.0	COG0457@1|root,COG0457@2|Bacteria,1G193@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,Glycos_transf_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
MMS3_k127_2741996_2	1267535.KB906767_gene3544	2.052e-26	117.0	COG2834@1|root,COG2834@2|Bacteria,3Y4XE@57723|Acidobacteria	57723|Acidobacteria	M	outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
MMS3_k127_2741996_1	204669.Acid345_4036	8.57e-46	177.0	COG0561@1|root,COG0561@2|Bacteria,3Y4J5@57723|Acidobacteria,2JJB7@204432|Acidobacteriia	204432|Acidobacteriia	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
MMS3_k127_2741996_0	204669.Acid345_2676	7.551e-170	550.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
MMS3_k127_2743224_0	1267533.KB906733_gene3429	1.462e-161	515.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
MMS3_k127_2743224_3	204669.Acid345_3450	1.347e-83	290.0	COG0768@1|root,COG0768@2|Bacteria,3Y3EP@57723|Acidobacteria,2JI45@204432|Acidobacteriia	204432|Acidobacteriia	M	penicillin-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
MMS3_k127_2743224_2	313624.NSP_30490	4.636e-114	372.0	COG0175@1|root,COG0175@2|Bacteria,1G1RY@1117|Cyanobacteria,1HJD0@1161|Nostocales	1117|Cyanobacteria	EH	Reduction of activated sulfate into sulfite	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
MMS3_k127_2743224_4	1341151.ASZU01000004_gene628	2.611e-37	151.0	COG0730@1|root,COG0730@2|Bacteria,1TQFD@1239|Firmicutes,4HG35@91061|Bacilli	91061|Bacilli	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_2743224_1	247490.KSU1_C0350	1.754e-147	478.0	COG2046@1|root,COG2046@2|Bacteria,2J517@203682|Planctomycetes	203682|Planctomycetes	H	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
MMS3_k127_2746265_6	234267.Acid_5909	2.015e-20	94.0	COG0483@1|root,COG0483@2|Bacteria,3Y3GD@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
MMS3_k127_2746265_4	1267535.KB906767_gene672	1.633e-62	223.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,3Y519@57723|Acidobacteria	57723|Acidobacteria	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
MMS3_k127_2746265_2	671143.DAMO_2354	7.111e-102	339.0	COG1090@1|root,COG1090@2|Bacteria,2NPHC@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
MMS3_k127_2746265_0	1121440.AUMA01000005_gene2707	3.313e-138	448.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2WNAF@28221|Deltaproteobacteria,2M9I9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
MMS3_k127_2746265_1	240015.ACP_1745	4.458e-128	420.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria,2JI2H@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
MMS3_k127_2746265_3	234267.Acid_1248	6.28e-75	260.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria	57723|Acidobacteria	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
MMS3_k127_2746265_7	1267535.KB906767_gene561	1.409e-09	60.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia	204432|Acidobacteriia	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
MMS3_k127_2746265_5	700598.Niako_5523	4.236e-28	114.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_2749390_4	1267533.KB906745_gene70	1.526e-15	83.0	COG3218@1|root,COG3218@2|Bacteria	2|Bacteria	Q	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
MMS3_k127_2749390_5	1282876.BAOK01000001_gene2361	0.000672	51.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2UCHU@28211|Alphaproteobacteria,4BQI6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	MlaD protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
MMS3_k127_2749390_0	1499967.BAYZ01000135_gene85	3.13e-93	313.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
MMS3_k127_2749390_1	1499967.BAYZ01000135_gene84	8.233e-67	240.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE_1	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
MMS3_k127_2749390_3	1430440.MGMSRv2_1737	1.344e-16	85.0	COG1366@1|root,COG1366@2|Bacteria,1N6U1@1224|Proteobacteria,2UFPK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
MMS3_k127_2749390_2	335543.Sfum_2452	1.484e-18	92.0	COG2172@1|root,COG2172@2|Bacteria,1N9EJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
MMS3_k127_2751339_12	880073.Calab_3403	1.129e-20	93.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria	2|Bacteria	C	Malic enzyme, NAD binding domain	maeB	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.38,1.1.1.40,2.3.1.8	ko:K00027,ko:K00029,ko:K00625,ko:K04020,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020	M00169,M00172,M00357,M00579	R00214,R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
MMS3_k127_2751339_13	1267535.KB906767_gene2388	1.127e-11	72.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
MMS3_k127_2751339_9	1232410.KI421428_gene1074	2.299e-40	154.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,43SIE@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
MMS3_k127_2751339_11	1267535.KB906767_gene571	1.796e-27	123.0	COG1729@1|root,COG1729@2|Bacteria,3Y3H6@57723|Acidobacteria,2JIES@204432|Acidobacteriia	204432|Acidobacteriia	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
MMS3_k127_2751339_5	234267.Acid_0513	6.497e-70	246.0	COG2885@1|root,COG2885@2|Bacteria,3Y3ZY@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
MMS3_k127_2751339_2	1382359.JIAL01000001_gene2342	5.809e-126	418.0	COG0823@1|root,COG0823@2|Bacteria,3Y2RC@57723|Acidobacteria,2JIV3@204432|Acidobacteriia	204432|Acidobacteriia	U	WD40-like Beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
MMS3_k127_2751339_10	204669.Acid345_0593	1.469e-38	157.0	COG0810@1|root,COG0810@2|Bacteria,3Y4WH@57723|Acidobacteria,2JJSC@204432|Acidobacteriia	204432|Acidobacteriia	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
MMS3_k127_2751339_8	204669.Acid345_0594	1.335e-43	164.0	COG0848@1|root,COG0848@2|Bacteria,3Y4QV@57723|Acidobacteria,2JJ9P@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
MMS3_k127_2751339_6	204669.Acid345_0595	1.476e-65	231.0	COG0811@1|root,COG0811@2|Bacteria,3Y2T8@57723|Acidobacteria,2JIN7@204432|Acidobacteriia	204432|Acidobacteriia	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
MMS3_k127_2751339_1	204669.Acid345_0596	6.156e-140	464.0	COG0497@1|root,COG0497@2|Bacteria,3Y2J4@57723|Acidobacteria,2JI9C@204432|Acidobacteriia	204432|Acidobacteriia	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
MMS3_k127_2751339_0	234267.Acid_6704	7.64e-176	569.0	COG0621@1|root,COG0621@2|Bacteria,3Y2GT@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
MMS3_k127_2751339_3	234267.Acid_6705	2.332e-79	268.0	COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria	57723|Acidobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
MMS3_k127_2751339_4	1047013.AQSP01000134_gene1378	2.117e-76	264.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMS3_k127_2751339_7	1047013.AQSP01000134_gene1379	8.92e-54	200.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
MMS3_k127_2757873_0	502025.Hoch_5119	3.562e-217	686.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales	28221|Deltaproteobacteria	C	Sulfite reductase	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
MMS3_k127_2758275_0	204669.Acid345_0704	4.534e-182	575.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMS3_k127_2758275_1	234267.Acid_5573	7.666e-134	433.0	COG0115@1|root,COG0115@2|Bacteria,3Y32X@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_2758275_4	234267.Acid_0793	7.6e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2758275_3	1267535.KB906767_gene3357	1.327e-104	345.0	COG0842@1|root,COG0842@2|Bacteria,3Y2S4@57723|Acidobacteria,2JISC@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_2758275_2	1267535.KB906767_gene3358	6.009e-119	391.0	COG1131@1|root,COG1131@2|Bacteria,3Y697@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2758275_5	240016.ABIZ01000001_gene3063	9.236e-35	142.0	COG1309@1|root,COG1309@2|Bacteria,46VBW@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2758372_0	240015.ACP_1399	6.433e-301	940.0	COG3537@1|root,COG3537@2|Bacteria,3Y2Z1@57723|Acidobacteria,2JIFF@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
MMS3_k127_2758372_3	754476.Q7A_2464	0.0005631	49.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,460TZ@72273|Thiotrichales	72273|Thiotrichales	G	Phosphoheptose isomerase	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
MMS3_k127_2758372_1	208444.JNYY01000010_gene2837	5.039e-207	670.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria,4DZET@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
MMS3_k127_2758372_2	1267534.KB906755_gene4817	1.497e-30	134.0	COG0457@1|root,COG0457@2|Bacteria,3Y78J@57723|Acidobacteria,2JMMI@204432|Acidobacteriia	204432|Acidobacteriia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMS3_k127_2758497_1	267608.RSc0196	2.302e-100	343.0	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2VJJF@28216|Betaproteobacteria,1K17Y@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2758497_2	234267.Acid_4384	8.367e-59	218.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria	57723|Acidobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_2758497_4	1121382.JQKG01000067_gene2612	3.021e-06	54.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMS3_k127_2758497_3	401053.AciPR4_1215	1.586e-38	151.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
MMS3_k127_2758497_0	401053.AciPR4_1216	3.13e-154	501.0	COG1290@1|root,COG1290@2|Bacteria,3Y4F0@57723|Acidobacteria,2JKSY@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C
MMS3_k127_2767_3	463191.SSEG_04672	2.397e-05	49.0	COG2819@1|root,COG2819@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
MMS3_k127_2767_2	391587.KAOT1_03712	1.062e-18	94.0	2CII3@1|root,32S83@2|Bacteria,4NT5V@976|Bacteroidetes,1I4AI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2767_0	584708.Apau_0054	3.209e-107	371.0	COG2984@1|root,COG2984@2|Bacteria,3TBSS@508458|Synergistetes	508458|Synergistetes	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
MMS3_k127_2767_1	929703.KE386491_gene1938	2.723e-67	232.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47NPG@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_2774271_2	234267.Acid_3330	3.024e-15	84.0	COG2948@1|root,COG2948@2|Bacteria	2|Bacteria	U	multi-organism process	-	-	-	ko:K03195	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbI
MMS3_k127_2774271_0	204669.Acid345_3344	4.688e-85	292.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
MMS3_k127_2774271_1	204669.Acid345_0705	7.352e-79	277.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria,2JI8N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
MMS3_k127_2778652_2	1408473.JHXO01000005_gene1607	2.288e-18	94.0	28RK7@1|root,2ZDZ1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2778652_1	1267533.KB906738_gene2336	6.82e-20	94.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
MMS3_k127_2778652_3	35754.JNYJ01000030_gene7744	0.0002224	51.0	COG1396@1|root,COG1396@2|Bacteria,2GNTQ@201174|Actinobacteria,4DDA1@85008|Micromonosporales	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
MMS3_k127_2778652_0	1384054.N790_10720	2.531e-60	221.0	arCOG08211@1|root,2ZBM3@2|Bacteria,1RIRV@1224|Proteobacteria,1SFXN@1236|Gammaproteobacteria,1X59H@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2785253_1	1340493.JNIF01000003_gene2882	2.036e-26	113.0	COG0004@1|root,COG0004@2|Bacteria,3Y2VR@57723|Acidobacteria	57723|Acidobacteria	P	TIGRFAM Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMS3_k127_2785253_0	401053.AciPR4_0496	3.323e-121	402.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria,2JM5G@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_2785253_2	1453500.AT05_02625	1.658e-07	55.0	COG0279@1|root,COG0279@2|Bacteria,4NKHI@976|Bacteroidetes	976|Bacteroidetes	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
MMS3_k127_2803767_2	1123372.AUIT01000006_gene1349	1.161e-30	121.0	COG0172@1|root,COG0172@2|Bacteria,2GGY4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
MMS3_k127_2803767_0	204669.Acid345_4476	9.719e-74	258.0	COG1230@1|root,COG1230@2|Bacteria,3Y32W@57723|Acidobacteria,2JIVH@204432|Acidobacteriia	204432|Acidobacteriia	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
MMS3_k127_2803767_1	1340493.JNIF01000003_gene3849	5.556e-52	199.0	COG2304@1|root,COG2304@2|Bacteria,3Y6QE@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
MMS3_k127_2809551_0	234267.Acid_4564	2.537e-55	217.0	COG1629@1|root,COG4771@2|Bacteria,3Y6A1@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_2809551_1	926566.Terro_4314	9.865e-06	59.0	COG1629@1|root,COG4771@2|Bacteria,3Y6CE@57723|Acidobacteria,2JK7M@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_2819504_3	794903.OPIT5_23815	1.813e-101	349.0	COG0591@1|root,COG0591@2|Bacteria,46UEN@74201|Verrucomicrobia,3K9NP@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
MMS3_k127_2819504_8	314230.DSM3645_18581	1.178e-66	242.0	COG4409@1|root,COG4409@2|Bacteria,2J286@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
MMS3_k127_2819504_7	485917.Phep_3567	1.295e-69	244.0	COG1028@1|root,COG1028@2|Bacteria,4NJK5@976|Bacteroidetes,1ITT3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_2819504_14	1047013.AQSP01000144_gene779	9.614e-36	148.0	COG0673@1|root,COG0673@2|Bacteria,2NRJY@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	ptmF	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_2819504_10	1248916.ANFY01000006_gene2004	4.33e-46	175.0	COG1802@1|root,COG1802@2|Bacteria,1P2DT@1224|Proteobacteria,2TSI4@28211|Alphaproteobacteria,2K6YI@204457|Sphingomonadales	204457|Sphingomonadales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS3_k127_2819504_11	211114.JOEF01000004_gene6388	8.388e-44	172.0	COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4E1YH@85010|Pseudonocardiales	201174|Actinobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_2819504_1	1267535.KB906767_gene5164	6.232e-143	475.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene5164|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2819504_6	485917.Phep_3584	2.439e-78	284.0	COG4409@1|root,COG4409@2|Bacteria,4NT25@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
MMS3_k127_2819504_5	344747.PM8797T_16028	9.665e-79	276.0	COG4409@1|root,COG4409@2|Bacteria,2J3X6@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
MMS3_k127_2819504_13	742735.HMPREF9467_04260	1.519e-36	149.0	COG0491@1|root,COG0491@2|Bacteria,1UZUA@1239|Firmicutes,24CIA@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_2819504_4	485917.Phep_3574	2.829e-85	294.0	COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1ITTX@117747|Sphingobacteriia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_2819504_2	1123508.JH636441_gene3382	3.152e-122	408.0	COG5476@1|root,COG5476@2|Bacteria,2IY2W@203682|Planctomycetes	203682|Planctomycetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
MMS3_k127_2819504_12	196164.23494622	8.922e-44	169.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,22KSK@1653|Corynebacteriaceae	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	idnO	-	1.1.1.100,1.1.1.69	ko:K00046,ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_2819504_9	314256.OG2516_00894	2.915e-47	182.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,2TSVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	succinylglutamate desuccinylase aspartoacylase	eutE	-	3.5.1.125	ko:K06987,ko:K15784	ko00260,ko01100,map00260,map01100	-	R09801	RC00064,RC00300	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
MMS3_k127_2819504_16	592316.Pat9b_1911	2.938e-14	84.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,3VYS1@53335|Pantoea	1236|Gammaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_2819504_15	509191.AEDB02000017_gene133	9.958e-18	94.0	COG3055@1|root,COG3055@2|Bacteria,1V5WF@1239|Firmicutes,24H47@186801|Clostridia,3WP75@541000|Ruminococcaceae	186801|Clostridia	N	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1
MMS3_k127_2819504_0	1340493.JNIF01000003_gene2004	5.481e-161	518.0	COG0001@1|root,COG0001@2|Bacteria,3Y3GA@57723|Acidobacteria	57723|Acidobacteria	H	PFAM Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_2819734_7	231434.JQJH01000022_gene1435	2.367e-13	70.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,2TUNB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG1335 Amidases related to nicotinamidase	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
MMS3_k127_2819734_4	231434.JQJH01000022_gene1436	4.176e-113	381.0	COG0174@1|root,COG0174@2|Bacteria,1MXPK@1224|Proteobacteria,2TUHR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
MMS3_k127_2819734_6	231434.JQJH01000022_gene1437	2.098e-70	256.0	COG0174@1|root,COG0174@2|Bacteria,1MXPK@1224|Proteobacteria,2TUHR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
MMS3_k127_2819734_1	1131814.JAFO01000001_gene3286	1.719e-154	501.0	COG0531@1|root,COG0531@2|Bacteria,1NQTH@1224|Proteobacteria,2TUFW@28211|Alphaproteobacteria,3F12X@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
MMS3_k127_2819734_5	234267.Acid_6731	8.428e-83	278.0	COG1309@1|root,COG1309@2|Bacteria,3Y4GK@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2819734_0	682795.AciX8_2349	2.385e-162	524.0	COG1028@1|root,COG1028@2|Bacteria,3Y3DK@57723|Acidobacteria,2JMNB@204432|Acidobacteriia	204432|Acidobacteriia	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2819734_2	1267534.KB906756_gene146	6.723e-140	455.0	COG0667@1|root,COG0667@2|Bacteria,3Y30P@57723|Acidobacteria,2JI04@204432|Acidobacteriia	204432|Acidobacteriia	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
MMS3_k127_2819734_3	876269.ARWA01000001_gene3143	6.242e-121	395.0	COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,2TSDE@28211|Alphaproteobacteria,3NA80@45404|Beijerinckiaceae	28211|Alphaproteobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_2828769_1	204669.Acid345_2952	2.932e-72	247.0	COG0015@1|root,COG0015@2|Bacteria,3Y2QW@57723|Acidobacteria,2JIAC@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
MMS3_k127_2828769_0	234267.Acid_7127	3.705e-91	309.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria	57723|Acidobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
MMS3_k127_2828769_2	1198114.AciX9_1356	1.626e-62	222.0	COG0163@1|root,COG0163@2|Bacteria,3Y2S8@57723|Acidobacteria,2JI3S@204432|Acidobacteriia	204432|Acidobacteriia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
MMS3_k127_2828769_3	1121447.JONL01000001_gene735	0.0001348	45.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2830387_3	1449063.JMLS01000020_gene5296	1.582e-09	59.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HB2V@91061|Bacilli,26SFU@186822|Paenibacillaceae	91061|Bacilli	G	Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
MMS3_k127_2830387_0	1408473.JHXO01000004_gene181	8.423e-163	520.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
MMS3_k127_2830387_1	1267535.KB906767_gene1164	1.982e-144	464.0	COG3386@1|root,COG3386@2|Bacteria,3Y5XH@57723|Acidobacteria,2JJAX@204432|Acidobacteriia	204432|Acidobacteriia	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMS3_k127_2830387_2	1267535.KB906767_gene1399	3.403e-78	268.0	COG0684@1|root,COG0684@2|Bacteria,3Y7HG@57723|Acidobacteria	57723|Acidobacteria	M	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
MMS3_k127_2838297_4	868131.MSWAN_1494	0.0002177	44.0	arCOG08232@1|root,arCOG08232@2157|Archaea,2Y5Y6@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2838297_1	639030.JHVA01000001_gene3444	1.009e-172	554.0	COG4289@1|root,COG4289@2|Bacteria,3Y462@57723|Acidobacteria,2JM7R@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterized protein conserved in bacteria (DUF2264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2264,TAT_signal
MMS3_k127_2838297_2	1340493.JNIF01000003_gene1829	3.371e-28	127.0	28IJE@1|root,2Z8KB@2|Bacteria,3Y46I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2838297_0	1382306.JNIM01000001_gene1354	1.098e-211	670.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMS3_k127_2838297_3	1198114.AciX9_3510	1.985e-10	68.0	2C0SZ@1|root,32R7J@2|Bacteria,3Y4ZA@57723|Acidobacteria,2JJII@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2852912_2	234267.Acid_0035	6.503e-112	381.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_0035|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2852912_1	1267535.KB906767_gene2751	5.75e-153	511.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2852912_3	204669.Acid345_0082	4.442e-26	111.0	COG0776@1|root,COG0776@2|Bacteria,3Y5E1@57723|Acidobacteria,2JJN0@204432|Acidobacteriia	204432|Acidobacteriia	L	Bacterial DNA-binding protein	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMS3_k127_2852912_0	313612.L8106_10192	2.516e-291	905.0	COG3387@1|root,COG3387@2|Bacteria,1G3VS@1117|Cyanobacteria,1H860@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
MMS3_k127_2855461_5	278963.ATWD01000001_gene2116	2.472e-15	75.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS3_k127_2855461_2	1198114.AciX9_0889	1.12e-50	192.0	COG1792@1|root,COG1792@2|Bacteria,3Y3CK@57723|Acidobacteria,2JIBI@204432|Acidobacteriia	204432|Acidobacteriia	M	Rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
MMS3_k127_2855461_4	234267.Acid_3813	6.729e-24	107.0	2CM1I@1|root,32SDF@2|Bacteria,3Y571@57723|Acidobacteria	57723|Acidobacteria	S	shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
MMS3_k127_2855461_0	234267.Acid_4180	5.216e-166	542.0	COG0768@1|root,COG0768@2|Bacteria,3Y3MX@57723|Acidobacteria	57723|Acidobacteria	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMS3_k127_2855461_1	204669.Acid345_1466	1.448e-103	347.0	COG0772@1|root,COG0772@2|Bacteria,3Y3DZ@57723|Acidobacteria,2JINX@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
MMS3_k127_2855461_3	1267535.KB906767_gene758	1.864e-29	127.0	COG1530@1|root,COG1530@2|Bacteria,3Y40K@57723|Acidobacteria,2JHQU@204432|Acidobacteriia	204432|Acidobacteriia	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
MMS3_k127_2858882_5	448385.sce7110	3.495e-93	310.0	COG0454@1|root,COG0456@2|Bacteria,1PWDA@1224|Proteobacteria,43586@68525|delta/epsilon subdivisions,2WZJ8@28221|Deltaproteobacteria,2Z296@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_2858882_3	204669.Acid345_4575	1.249e-124	409.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,3Y65Z@57723|Acidobacteria,2JM5S@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_2858882_2	204669.Acid345_4576	3.316e-127	414.0	COG1131@1|root,COG1131@2|Bacteria,3Y3PY@57723|Acidobacteria,2JIQU@204432|Acidobacteriia	204432|Acidobacteriia	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2858882_7	204669.Acid345_4577	9.072e-55	209.0	COG1566@1|root,COG1566@2|Bacteria,3Y6U1@57723|Acidobacteria,2JKUF@204432|Acidobacteriia	204432|Acidobacteriia	V	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_D23
MMS3_k127_2858882_9	1267533.KB906740_gene155	2.268e-27	119.0	COG1309@1|root,COG1309@2|Bacteria,3Y8NY@57723|Acidobacteria,2JNEU@204432|Acidobacteriia	204432|Acidobacteriia	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
MMS3_k127_2858882_1	1382306.JNIM01000001_gene3774	1.297e-129	424.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
MMS3_k127_2858882_4	1382359.JIAL01000001_gene624	2.572e-114	376.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_2858882_0	1267535.KB906767_gene5021	5.638e-203	640.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria,2JI7K@204432|Acidobacteriia	204432|Acidobacteriia	J	class II (D K	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS3_k127_2858882_6	234267.Acid_2806	1.563e-72	254.0	COG1082@1|root,COG1082@2|Bacteria,3Y4EN@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_2858882_8	1173028.ANKO01000035_gene3696	3.425e-43	161.0	COG0405@1|root,COG0405@2|Bacteria,1G14N@1117|Cyanobacteria,1H83V@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_2874525_2	1123373.ATXI01000017_gene268	6.774e-13	73.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_4,Phage_integrase
MMS3_k127_2874525_0	1267535.KB906767_gene1958	1.13e-200	662.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480,ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
MMS3_k127_2874525_1	1267535.KB906767_gene1959	3.151e-68	238.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_2881479_7	1410666.JHXG01000001_gene939	1.551e-20	92.0	COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,2FN5N@200643|Bacteroidia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	3.2.1.197	ko:K21065	-	-	R11544	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
MMS3_k127_2881479_0	234267.Acid_1492	2.423e-260	809.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria	57723|Acidobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMS3_k127_2881479_9	204669.Acid345_0179	2.115e-12	74.0	2EN0M@1|root,337VJ@2|Bacteria,3Y5R9@57723|Acidobacteria,2JNZF@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2881479_6	1198114.AciX9_0423	1.533e-27	126.0	COG4733@1|root,COG4733@2|Bacteria,3Y53H@57723|Acidobacteria,2JJMD@204432|Acidobacteriia	204432|Acidobacteriia	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2881479_1	234267.Acid_7339	3.275e-219	691.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria	57723|Acidobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
MMS3_k127_2881479_3	234267.Acid_7340	3.344e-79	268.0	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria	57723|Acidobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
MMS3_k127_2881479_8	1382359.JIAL01000001_gene1901	2.682e-20	101.0	2A6XZ@1|root,30VSX@2|Bacteria,3Y4RH@57723|Acidobacteria,2JJCB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2881479_4	1379698.RBG1_1C00001G1640	4.009e-72	251.0	COG1028@1|root,COG1028@2|Bacteria,2NP4D@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_2881479_5	234267.Acid_5659	6.661e-54	199.0	COG0204@1|root,COG0204@2|Bacteria,3Y4EM@57723|Acidobacteria	57723|Acidobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS3_k127_2881479_2	671143.DAMO_1989	2.23e-94	325.0	COG0285@1|root,COG0285@2|Bacteria,2NP60@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the folylpolyglutamate synthase family	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0166,iSB619.SA_RS08370	Mur_ligase_C,Mur_ligase_M
MMS3_k127_2887596_2	234267.Acid_0167	2.242e-103	342.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,3Y2Q1@57723|Acidobacteria	57723|Acidobacteria	CJ	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
MMS3_k127_2887596_0	240015.ACP_3070	9.559e-221	695.0	COG1506@1|root,COG1506@2|Bacteria,3Y9BP@57723|Acidobacteria,2JP0C@204432|Acidobacteriia	204432|Acidobacteriia	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2887596_1	685778.AORL01000010_gene2678	1.25e-107	353.0	COG2755@1|root,COG2755@2|Bacteria,1MXBN@1224|Proteobacteria,2U079@28211|Alphaproteobacteria,2K27U@204457|Sphingomonadales	204457|Sphingomonadales	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMS3_k127_2898704_2	1125863.JAFN01000001_gene1761	9.43e-98	327.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
MMS3_k127_2898704_0	1125863.JAFN01000001_gene1760	6.751e-110	371.0	COG3581@1|root,COG3581@2|Bacteria,1PDHS@1224|Proteobacteria,43DP1@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
MMS3_k127_2898704_1	405948.SACE_5173	4.466e-98	339.0	COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria,4DZVQ@85010|Pseudonocardiales	201174|Actinobacteria	G	Altronate dehydratase	-	-	4.2.1.42,4.2.1.7	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00631	R01540,R05608	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
MMS3_k127_2917708_2	1173024.KI912149_gene6404	6.486e-73	259.0	COG1404@1|root,COG1404@2|Bacteria,1G2F0@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
MMS3_k127_2917708_0	941449.dsx2_2455	4.912e-213	670.0	COG0160@1|root,COG0160@2|Bacteria,1QTZ3@1224|Proteobacteria,43D42@68525|delta/epsilon subdivisions,2X8AU@28221|Deltaproteobacteria,2MHF9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_2917708_5	438753.AZC_3989	2.001e-41	165.0	COG4359@1|root,COG4359@2|Bacteria,1REUD@1224|Proteobacteria,2U9HY@28211|Alphaproteobacteria,3F1D6@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
MMS3_k127_2917708_3	521045.Kole_0623	7.964e-53	203.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
MMS3_k127_2917708_4	1009370.ALO_01205	1.945e-43	174.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4H2TU@909932|Negativicutes	1239|Firmicutes	M	Monogalactosyldiacylglycerol synthase, C-terminal domain protein	ypfP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
MMS3_k127_2917708_1	1163407.UU7_01117	2.074e-126	416.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1X3GS@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	ko:K14660	-	-	-	-	ko00000,ko01000	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMS3_k127_2917708_6	1340493.JNIF01000003_gene2927	7.603e-14	75.0	COG0236@1|root,COG0236@2|Bacteria,3Y8JV@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
MMS3_k127_2933670_3	204669.Acid345_3766	1.039e-12	68.0	COG0312@1|root,COG0312@2|Bacteria,3Y7SM@57723|Acidobacteria	57723|Acidobacteria	L	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
MMS3_k127_2933670_2	1318628.MARLIPOL_16209	9.593e-24	111.0	COG0589@1|root,COG0589@2|Bacteria,1N31F@1224|Proteobacteria,1S903@1236|Gammaproteobacteria,46BDD@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2933670_0	266117.Rxyl_1929	1.337e-314	982.0	COG1067@1|root,COG1067@2|Bacteria,2H2TE@201174|Actinobacteria	201174|Actinobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
MMS3_k127_2933670_1	240292.Ava_4088	3.843e-48	177.0	COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,1HRYE@1161|Nostocales	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2945569_4	404589.Anae109_1572	3.28e-74	261.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,43AKP@68525|delta/epsilon subdivisions,2X60N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
MMS3_k127_2945569_0	278963.ATWD01000001_gene2872	3.633e-160	516.0	COG4975@1|root,COG4975@2|Bacteria,3Y2SZ@57723|Acidobacteria,2JITY@204432|Acidobacteriia	204432|Acidobacteriia	G	Sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_transport
MMS3_k127_2945569_1	234267.Acid_4072	4.927e-130	424.0	KOG1573@1|root,2Z822@2|Bacteria,3Y3AN@57723|Acidobacteria	57723|Acidobacteria	S	Myo-inositol oxygenase	-	-	1.13.99.1	ko:K00469	ko00053,ko00562,map00053,map00562	-	R01184	RC00465	ko00000,ko00001,ko01000	-	-	-	MIOX
MMS3_k127_2945569_3	234267.Acid_2678	8.258e-118	391.0	COG1940@1|root,COG1940@2|Bacteria,3Y3B2@57723|Acidobacteria	57723|Acidobacteria	GK	PFAM ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
MMS3_k127_2945569_2	1267535.KB906767_gene4432	4.703e-127	424.0	COG1629@1|root,COG1629@2|Bacteria,3Y620@57723|Acidobacteria,2JKZX@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_2945619_1	204669.Acid345_0660	1.669e-93	314.0	COG0524@1|root,COG0524@2|Bacteria,3Y44M@57723|Acidobacteria,2JIAD@204432|Acidobacteriia	204432|Acidobacteriia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
MMS3_k127_2945619_2	401053.AciPR4_1443	1.276e-87	301.0	COG2222@1|root,COG2222@2|Bacteria,3Y7AN@57723|Acidobacteria,2JKS7@204432|Acidobacteriia	204432|Acidobacteriia	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
MMS3_k127_2945619_0	1454007.JAUG01000047_gene512	1.19e-127	417.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1ISF7@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_2945619_3	234267.Acid_4808	2.238e-66	233.0	COG0524@1|root,COG0524@2|Bacteria,3Y659@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.184	ko:K18478	-	-	R10970	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
MMS3_k127_2950137_1	1267535.KB906767_gene582	3.004e-28	115.0	COG0704@1|root,COG0704@2|Bacteria,3Y4DI@57723|Acidobacteria,2JJ5M@204432|Acidobacteriia	204432|Acidobacteriia	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
MMS3_k127_2950137_0	234267.Acid_0103	8.652e-160	520.0	COG0477@1|root,COG2814@2|Bacteria,3Y2YV@57723|Acidobacteria	57723|Acidobacteria	EGP	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
MMS3_k127_2950137_3	1122243.KB903793_gene1839	1.138e-26	110.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,3NPC2@468|Moraxellaceae	1236|Gammaproteobacteria	K	'Cold-shock' DNA-binding domain	capB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_2950137_2	240015.ACP_2535	5.303e-28	121.0	COG0071@1|root,COG0071@2|Bacteria,3Y8FE@57723|Acidobacteria,2JNDQ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934,HSP20
MMS3_k127_2951574_2	1267535.KB906767_gene2136	5.251e-38	147.0	COG0673@1|root,COG0673@2|Bacteria,3Y78W@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_2951574_1	1089551.KE386572_gene3635	3.516e-50	186.0	COG0684@1|root,COG0684@2|Bacteria,1MUWV@1224|Proteobacteria,2TU1X@28211|Alphaproteobacteria,4BS14@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
MMS3_k127_2951574_0	1111479.AXAR01000004_gene2231	2.316e-106	359.0	COG2271@1|root,COG2271@2|Bacteria,1TS8X@1239|Firmicutes,4HE0A@91061|Bacilli	91061|Bacilli	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2951574_3	880074.BARVI_00295	6.11e-23	106.0	COG0351@1|root,COG0351@2|Bacteria,4NE0F@976|Bacteroidetes,2FNNE@200643|Bacteroidia,22XEP@171551|Porphyromonadaceae	976|Bacteroidetes	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
MMS3_k127_2958371_2	278963.ATWD01000001_gene2701	1.173e-21	101.0	COG2963@1|root,COG2963@2|Bacteria,3Y86N@57723|Acidobacteria,2JN5S@204432|Acidobacteriia	204432|Acidobacteriia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
MMS3_k127_2958371_1	869210.Marky_1959	1.27e-53	201.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,1WIAB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
MMS3_k127_2958371_3	278963.ATWD01000001_gene1073	0.0002065	44.0	COG2963@1|root,COG2963@2|Bacteria,3Y86J@57723|Acidobacteria,2JN6K@204432|Acidobacteriia	204432|Acidobacteriia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
MMS3_k127_2958371_0	1123248.KB893381_gene946	1.308e-212	691.0	COG1073@1|root,COG1073@2|Bacteria,4NG6A@976|Bacteroidetes	976|Bacteroidetes	G	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,BAAT_C,Hydrolase_4
MMS3_k127_2965416_3	204669.Acid345_3370	1.71e-131	438.0	COG2366@1|root,COG2366@2|Bacteria,3Y2PX@57723|Acidobacteria,2JHKH@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
MMS3_k127_2965416_1	234267.Acid_4336	1.848e-153	505.0	COG4805@1|root,COG4805@2|Bacteria,3Y47D@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
MMS3_k127_2965416_4	204669.Acid345_0628	2.145e-42	163.0	COG0586@1|root,COG0586@2|Bacteria,3Y7VY@57723|Acidobacteria,2JMWT@204432|Acidobacteriia	204432|Acidobacteriia	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
MMS3_k127_2965416_2	644966.Tmar_1299	3.506e-144	468.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WD3X@538999|Clostridiales incertae sedis	186801|Clostridia	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_2965416_5	1267535.KB906767_gene2672	5.675e-37	144.0	COG1610@1|root,COG1610@2|Bacteria,3Y4VF@57723|Acidobacteria,2JJJH@204432|Acidobacteriia	204432|Acidobacteriia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
MMS3_k127_2965416_0	1047013.AQSP01000071_gene1939	3.19e-200	646.0	COG1297@1|root,COG1297@2|Bacteria,2NP0C@2323|unclassified Bacteria	2|Bacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
MMS3_k127_2970908_8	204669.Acid345_2374	1.641e-27	117.0	COG1648@1|root,COG1648@2|Bacteria,3Y4XH@57723|Acidobacteria,2JJKI@204432|Acidobacteriia	204432|Acidobacteriia	H	Sirohaem biosynthesis protein central	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
MMS3_k127_2970908_7	330214.NIDE3895	1.055e-28	121.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	ymaD	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
MMS3_k127_2970908_5	1121405.dsmv_0235	8.526e-43	167.0	COG1102@1|root,COG1102@2|Bacteria,1R1X4@1224|Proteobacteria,43DC5@68525|delta/epsilon subdivisions,2X8I5@28221|Deltaproteobacteria,2MPI3@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
MMS3_k127_2970908_1	1303518.CCALI_01334	3.318e-94	316.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	yxaA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_2970908_3	1303518.CCALI_01334	6.733e-82	280.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	yxaA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_2970908_6	1121918.ARWE01000001_gene3348	3.595e-40	160.0	COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2WJS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
MMS3_k127_2970908_9	56107.Cylst_2697	5.702e-22	99.0	COG4272@1|root,COG4272@2|Bacteria,1G77S@1117|Cyanobacteria,1HNTC@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
MMS3_k127_2970908_2	1303518.CCALI_01334	4.544e-94	316.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	yxaA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_2970908_4	1122223.KB890688_gene1888	2.184e-81	280.0	COG0730@1|root,COG0730@2|Bacteria,1WJ2X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_2970908_0	335543.Sfum_1046	1.254e-174	556.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2MR3M@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
MMS3_k127_2970908_10	1517681.HW45_24820	1.47e-05	54.0	COG3303@1|root,COG3303@2|Bacteria,1REFF@1224|Proteobacteria,1S5HC@1236|Gammaproteobacteria,1XSAS@135623|Vibrionales	135623|Vibrionales	C	Cytochrome c554 and c-prime	nrfB	-	-	ko:K04013	-	-	-	-	ko00000	-	-	-	Cytochrome_C554,Paired_CXXCH_1
MMS3_k127_2971560_5	756272.Plabr_3042	2.833e-56	201.0	COG3476@1|root,COG3476@2|Bacteria,2J03F@203682|Planctomycetes	203682|Planctomycetes	T	PFAM TspO MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
MMS3_k127_2971560_3	330214.NIDE0204	4.921e-104	355.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,3J13F@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
MMS3_k127_2971560_1	344747.PM8797T_16917	2.247e-139	450.0	COG0276@1|root,COG0276@2|Bacteria,2IX75@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
MMS3_k127_2971560_4	204669.Acid345_4513	1.435e-96	331.0	COG1668@1|root,COG1668@2|Bacteria,3Y2XV@57723|Acidobacteria,2JIQK@204432|Acidobacteriia	204432|Acidobacteriia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_2971560_2	204669.Acid345_4512	1.487e-118	394.0	COG4152@1|root,COG4152@2|Bacteria,3Y2NV@57723|Acidobacteria,2JHVX@204432|Acidobacteriia	204432|Acidobacteriia	S	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_2971560_0	682795.AciX8_3829	3.502e-289	893.0	COG2723@1|root,COG2723@2|Bacteria,3Y484@57723|Acidobacteria,2JIKZ@204432|Acidobacteriia	2|Bacteria	G	PFAM glycoside hydrolase family 1	blgA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
MMS3_k127_29935_3	34506.g2012	1.26e-06	54.0	COG1232@1|root,2QQ27@2759|Eukaryota,38NWR@33154|Opisthokonta,3BJ2A@33208|Metazoa,3CW61@33213|Bilateria,40BH8@6231|Nematoda,1KTMK@119089|Chromadorea,40UJ4@6236|Rhabditida	33208|Metazoa	H	Flavin containing amine oxidoreductase	-	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008767,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044464,GO:0071704,GO:1901576	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMS3_k127_29935_0	401526.TcarDRAFT_0348	4.635e-31	140.0	COG0726@1|root,COG0726@2|Bacteria,1U25I@1239|Firmicutes,4H25P@909932|Negativicutes	909932|Negativicutes	G	Polysaccharide deacetylase	pgaB_2	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_29935_1	1122222.AXWR01000002_gene2154	8.153e-30	136.0	COG1216@1|root,COG1216@2|Bacteria,1WM2W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
MMS3_k127_29935_2	891968.Anamo_1233	2.442e-12	79.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	rfbE	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
MMS3_k127_2999013_1	234267.Acid_1175	6.079e-81	274.0	COG0531@1|root,COG0531@2|Bacteria,3Y2R3@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMS3_k127_2999013_3	468059.AUHA01000002_gene29	1.089e-44	176.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1IPV1@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
MMS3_k127_2999013_2	1463845.JOIG01000012_gene248	8.756e-64	233.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add2	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
MMS3_k127_2999013_4	671143.DAMO_0482	2.313e-29	126.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
MMS3_k127_2999013_0	1382359.JIAL01000001_gene1341	2.215e-229	738.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_3011215_2	204669.Acid345_1473	0.0002124	53.0	COG4796@1|root,COG4796@2|Bacteria,3Y98D@57723|Acidobacteria	57723|Acidobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
MMS3_k127_3011215_0	478741.JAFS01000001_gene2211	6.361e-82	277.0	COG1225@1|root,COG1225@2|Bacteria,46SWU@74201|Verrucomicrobia,37GJJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
MMS3_k127_3011215_1	706587.Desti_3270	1.911e-73	269.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
MMS3_k127_3044975_5	671143.DAMO_0768	2.213e-24	111.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
MMS3_k127_3044975_1	269799.Gmet_2119	2.495e-79	274.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria,43UCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome b(N-terminal)/b6/petB	pcmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
MMS3_k127_3044975_4	247490.KSU1_D0608	7.482e-25	111.0	COG0723@1|root,COG0723@2|Bacteria,2J2T1@203682|Planctomycetes	203682|Planctomycetes	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
MMS3_k127_3044975_0	671143.DAMO_0766	3.864e-186	603.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,2NNUW@2323|unclassified Bacteria	2|Bacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	pcmB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9	ko:K03388,ko:K12527	ko00450,ko00680,ko01100,ko01120,ko01200,map00450,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R07229,R11928,R11931,R11943,R11944	RC00011,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,FlpD,Pyr_redox_2,Pyr_redox_3
MMS3_k127_3044975_3	247490.KSU1_B0256	1.653e-44	169.0	COG3794@1|root,COG3794@2|Bacteria,2J29W@203682|Planctomycetes	203682|Planctomycetes	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_3044975_6	330214.NIDE3793	3.145e-20	105.0	29W26@1|root,30HKR@2|Bacteria,3J1BV@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3044975_2	1120999.JONM01000003_gene2723	1.857e-47	175.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,2KQ5T@206351|Neisseriales	206351|Neisseriales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMS3_k127_3048963_1	1047013.AQSP01000139_gene2392	7.383e-111	366.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_3048963_4	13333.ERN12645	1.114e-14	75.0	COG0372@1|root,KOG2617@2759|Eukaryota,37JED@33090|Viridiplantae,3GF4T@35493|Streptophyta	35493|Streptophyta	C	Belongs to the citrate synthase family	-	GO:0000166,GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009507,GO:0009536,GO:0009987,GO:0010035,GO:0010038,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0019752,GO:0030312,GO:0030554,GO:0031974,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036440,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046686,GO:0046872,GO:0046912,GO:0046914,GO:0050896,GO:0055114,GO:0070013,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_3048963_3	159087.Daro_0648	4.513e-30	126.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,2KWBK@206389|Rhodocyclales	206389|Rhodocyclales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
MMS3_k127_3048963_5	316274.Haur_2366	0.0006758	48.0	COG2204@1|root,COG2204@2|Bacteria,2G5ZP@200795|Chloroflexi	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714,ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	M00500	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat,TPR_12
MMS3_k127_3048963_0	880073.Calab_3529	2.826e-165	532.0	COG0677@1|root,COG0677@2|Bacteria,2NNQ1@2323|unclassified Bacteria	2|Bacteria	M	UDP binding domain	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_3048963_2	1340493.JNIF01000003_gene3506	4.881e-56	204.0	COG2362@1|root,COG2362@2|Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
MMS3_k127_3072154_0	1267533.KB906734_gene3857	7.016e-133	451.0	COG3525@1|root,COG3525@2|Bacteria,3Y77I@57723|Acidobacteria,2JKDD@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
MMS3_k127_3072154_1	204669.Acid345_2377	7.225e-23	104.0	COG1228@1|root,COG1228@2|Bacteria,3Y2MZ@57723|Acidobacteria,2JI4B@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_3072154_3	384765.SIAM614_24667	3.496e-13	80.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidylprolyl isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
MMS3_k127_3072154_2	240015.ACP_1006	1.193e-21	96.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_3077311_3	234267.Acid_1921	2.32e-84	295.0	COG3852@1|root,COG3852@2|Bacteria,3Y9A1@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMS3_k127_3077311_1	234267.Acid_1922	5.612e-181	577.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3077311_4	795359.TOPB45_1098	1.216e-30	131.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	recB	-	3.6.4.12	ko:K03657,ko:K16898	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF3799,PDDEXK_1,UvrD-helicase,UvrD_C
MMS3_k127_3077311_2	1340493.JNIF01000004_gene649	5.031e-102	362.0	COG3266@1|root,COG3266@2|Bacteria,3Y4N4@57723|Acidobacteria	57723|Acidobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
MMS3_k127_3077311_0	452637.Oter_1004	2.128e-244	769.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3,Sugar_tr
MMS3_k127_3077311_5	111781.Lepto7376_0290	2.806e-11	73.0	COG0457@1|root,COG0457@2|Bacteria,1G1G9@1117|Cyanobacteria,1H889@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
MMS3_k127_3078238_1	234267.Acid_1175	6.823e-95	317.0	COG0531@1|root,COG0531@2|Bacteria,3Y2R3@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMS3_k127_3078238_3	278963.ATWD01000001_gene3812	4.704e-06	52.0	2EKUV@1|root,33EIF@2|Bacteria,3Y5VB@57723|Acidobacteria,2JK46@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3078238_2	398512.JQKC01000008_gene949	6.839e-26	115.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,3WKSE@541000|Ruminococcaceae	186801|Clostridia	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
MMS3_k127_3078238_0	234267.Acid_1174	9.126e-222	709.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria	57723|Acidobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
MMS3_k127_3081222_1	1047013.AQSP01000142_gene235	3.094e-69	241.0	COG1063@1|root,COG1063@2|Bacteria,2NPFX@2323|unclassified Bacteria	2|Bacteria	E	Glucose dehydrogenase C-terminus	ydjJ	-	1.1.1.14,1.1.1.9	ko:K00008,ko:K05351	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3081222_0	240015.ACP_0738	5.744e-97	325.0	COG3823@1|root,COG3823@2|Bacteria,3Y4G6@57723|Acidobacteria,2JMG7@204432|Acidobacteriia	204432|Acidobacteriia	M	Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
MMS3_k127_3081222_2	868131.MSWAN_1494	4.231e-18	91.0	arCOG08232@1|root,arCOG08232@2157|Archaea,2Y5Y6@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3085352_2	1195236.CTER_0563	1.694e-46	177.0	COG0145@1|root,COG0145@2|Bacteria,1V3GN@1239|Firmicutes,25DNJ@186801|Clostridia,3WPEF@541000|Ruminococcaceae	186801|Clostridia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
MMS3_k127_3085352_3	1313172.YM304_41760	1.425e-10	65.0	COG0646@1|root,COG0646@2|Bacteria,2IEWZ@201174|Actinobacteria	201174|Actinobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
MMS3_k127_3085352_4	1267535.KB906767_gene4331	1.685e-07	64.0	28MYB@1|root,2ZB57@2|Bacteria,3Y32P@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3085352_1	240015.ACP_0069	8.708e-72	258.0	COG3119@1|root,COG3119@2|Bacteria,3Y2QE@57723|Acidobacteria,2JKHV@204432|Acidobacteriia	204432|Acidobacteriia	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3085352_0	1267535.KB906767_gene1401	5.425e-198	631.0	COG3664@1|root,COG3664@2|Bacteria	2|Bacteria	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39
MMS3_k127_3094561_3	240015.ACP_3135	4.865e-60	216.0	COG0337@1|root,COG0337@2|Bacteria,3Y2T4@57723|Acidobacteria,2JI0C@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
MMS3_k127_3094561_0	1340493.JNIF01000003_gene3112	1.833e-152	500.0	COG0029@1|root,COG0029@2|Bacteria,3Y39F@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_3094561_1	1267535.KB906767_gene4620	1.78e-84	290.0	COG2234@1|root,COG2234@2|Bacteria,3Y406@57723|Acidobacteria,2JIRZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_3094561_2	1267533.KB906733_gene3515	1.289e-80	277.0	COG0805@1|root,COG0805@2|Bacteria,3Y3UC@57723|Acidobacteria,2JISU@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
MMS3_k127_3094561_4	234267.Acid_2827	5.64e-09	65.0	COG1826@1|root,COG1826@2|Bacteria,3Y5TY@57723|Acidobacteria	57723|Acidobacteria	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_31417_1	216596.RL2873	2.161e-41	166.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TUKX@28211|Alphaproteobacteria,4BAF2@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	-
MMS3_k127_31417_0	204669.Acid345_2812	8.587e-204	647.0	COG0364@1|root,COG0364@2|Bacteria,3Y2JZ@57723|Acidobacteria,2JHKE@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
MMS3_k127_31417_3	338963.Pcar_0549	1.366e-07	63.0	COG1704@1|root,COG1704@2|Bacteria,1RF5E@1224|Proteobacteria,42S8B@68525|delta/epsilon subdivisions,2WNYZ@28221|Deltaproteobacteria,43U7E@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	E3 Ubiquitin ligase	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
MMS3_k127_31417_2	338963.Pcar_0548	7.735e-24	104.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42S15@68525|delta/epsilon subdivisions,2WNI1@28221|Deltaproteobacteria,43T5E@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
MMS3_k127_3241150_2	886293.Sinac_5803	2.367e-123	398.0	COG0667@1|root,COG0667@2|Bacteria,2IXBS@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_3241150_7	1144325.PMI22_03109	1.604e-59	223.0	COG3659@1|root,COG3659@2|Bacteria,1R591@1224|Proteobacteria,1RRM9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
MMS3_k127_3241150_6	1382359.JIAL01000001_gene2053	3.748e-67	232.0	COG1942@1|root,COG4334@1|root,COG1942@2|Bacteria,COG4334@2|Bacteria,3Y8F4@57723|Acidobacteria,2JNSH@204432|Acidobacteriia	204432|Acidobacteriia	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
MMS3_k127_3241150_5	1198114.AciX9_0562	4.73e-69	235.0	COG1917@1|root,COG1917@2|Bacteria,3Y4HX@57723|Acidobacteria,2JJ92@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_3241150_9	1192868.CAIU01000023_gene3455	6.428e-26	108.0	COG1942@1|root,COG1942@2|Bacteria,1PUKM@1224|Proteobacteria,2V676@28211|Alphaproteobacteria,43QS1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Tautomerase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Tautomerase
MMS3_k127_3241150_0	1382359.JIAL01000001_gene2052	7.439e-200	625.0	COG1064@1|root,COG1064@2|Bacteria,3Y33B@57723|Acidobacteria,2JI1P@204432|Acidobacteriia	204432|Acidobacteriia	S	Zinc-binding dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3241150_8	1117943.SFHH103_02561	7.686e-42	159.0	COG0599@1|root,COG0599@2|Bacteria,1NN7W@1224|Proteobacteria,2TVCR@28211|Alphaproteobacteria,4BEUK@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	homolog of gamma-carboxymuconolactone decarboxylase subunit	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMS3_k127_3241150_1	706587.Desti_1960	4.007e-125	408.0	COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,43CQR@68525|delta/epsilon subdivisions,2X7Y7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
MMS3_k127_3241150_4	1267535.KB906767_gene473	1.093e-70	255.0	28JXN@1|root,30T38@2|Bacteria,3Y61P@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
MMS3_k127_3241150_3	290512.Paes_1239	1.365e-87	293.0	COG1249@1|root,COG1249@2|Bacteria,1FER2@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_3280846_6	1128421.JAGA01000002_gene1841	4.617e-20	98.0	COG3429@1|root,COG3429@2|Bacteria	2|Bacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem,PG_binding_1
MMS3_k127_3280846_4	314278.NB231_12536	1.77e-59	215.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1SYT9@1236|Gammaproteobacteria,1X25R@135613|Chromatiales	135613|Chromatiales	G	PFAM glucosamine galactosamine-6-phosphate isomerase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
MMS3_k127_3280846_3	1382306.JNIM01000001_gene770	2.67e-81	277.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
MMS3_k127_3280846_1	1206741.BAFX01000183_gene7615	6.163e-128	423.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4FUYT@85025|Nocardiaceae	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	algD	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_3280846_5	267748.MMOB6010	4.662e-50	190.0	COG1004@1|root,COG1004@2|Bacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_3280846_0	479434.Sthe_2758	5.167e-128	419.0	COG0399@1|root,COG0399@2|Bacteria,2G5QG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_3280846_2	330214.NIDE3419	2.226e-83	293.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,Glyco_trans_1_4,NAD_binding_8
MMS3_k127_3283200_3	471854.Dfer_4598	7.84e-11	73.0	COG2244@1|root,COG2244@2|Bacteria,4NHJV@976|Bacteroidetes,47QGQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt,Polysacc_synt_C
MMS3_k127_3283200_0	682795.AciX8_1493	4.184e-55	210.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_3283200_1	682795.AciX8_1491	1.136e-45	183.0	COG2956@1|root,COG2956@2|Bacteria	2|Bacteria	G	lipopolysaccharide metabolic process	-	-	-	ko:K08309,ko:K19804	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
MMS3_k127_3283200_2	941824.TCEL_01632	5.765e-31	129.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,36DN2@31979|Clostridiaceae	186801|Clostridia	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA
MMS3_k127_3284617_3	1267535.KB906767_gene1828	3.872e-147	476.0	COG3518@1|root,COG3518@2|Bacteria	2|Bacteria	S	anti-sigma factor antagonist activity	iraD	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033554,GO:0042176,GO:0042177,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11897,ko:K21637	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
MMS3_k127_3284617_5	1382359.JIAL01000001_gene1593	4.471e-11	68.0	COG1629@1|root,COG4771@2|Bacteria,3Y2R5@57723|Acidobacteria,2JIK7@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_3284617_2	1267535.KB906767_gene4514	6.647e-150	489.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_3284617_0	1267535.KB906767_gene4515	1.133e-227	715.0	COG1012@1|root,COG1012@2|Bacteria,3Y384@57723|Acidobacteria,2JIA8@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K00138,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_3284617_1	1267535.KB906767_gene4516	3.634e-161	519.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA1	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
MMS3_k127_3284617_4	1297742.A176_05165	1.55e-54	196.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42MBY@68525|delta/epsilon subdivisions,2WIR5@28221|Deltaproteobacteria,2YUKC@29|Myxococcales	28221|Deltaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.61	ko:K00043	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
MMS3_k127_3287734_2	234267.Acid_5485	3.727e-26	110.0	COG0841@1|root,COG0841@2|Bacteria,3Y3F4@57723|Acidobacteria	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMS3_k127_3287734_0	1267535.KB906767_gene5351	3.39e-102	346.0	COG0845@1|root,COG0845@2|Bacteria,3Y3C9@57723|Acidobacteria,2JIN9@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
MMS3_k127_3287734_1	1267535.KB906767_gene5350	4.826e-66	233.0	COG1538@1|root,COG1538@2|Bacteria,3Y3PX@57723|Acidobacteria,2JHUZ@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_3291249_0	1499967.BAYZ01000030_gene1163	2.661e-57	205.0	COG0755@1|root,COG0755@2|Bacteria,2NPG8@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
MMS3_k127_3291249_2	552811.Dehly_0439	4.552e-47	178.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
MMS3_k127_3291249_1	717231.Flexsi_2161	1.487e-49	185.0	COG1131@1|root,COG1131@2|Bacteria,2GERZ@200930|Deferribacteres	200930|Deferribacteres	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
MMS3_k127_3291249_3	204669.Acid345_3204	9.196e-15	87.0	28K54@1|root,2Z9TW@2|Bacteria,3Y3Z7@57723|Acidobacteria,2JHS9@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3291249_5	234267.Acid_4234	2.129e-11	70.0	2EFR0@1|root,339H2@2|Bacteria,3Y5M9@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3291249_4	1487923.DP73_10870	1.79e-11	68.0	COG3088@1|root,COG3088@2|Bacteria,1VETA@1239|Firmicutes,24TPT@186801|Clostridia,265EA@186807|Peptococcaceae	186801|Clostridia	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
MMS3_k127_3305063_0	234267.Acid_6681	6.093e-164	527.0	COG1271@1|root,COG1271@2|Bacteria,3Y44V@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
MMS3_k127_3305063_1	635013.TherJR_0853	2.544e-84	290.0	COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,24CPA@186801|Clostridia,261EQ@186807|Peptococcaceae	186801|Clostridia	C	oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
MMS3_k127_3305063_2	204669.Acid345_1498	3.268e-24	110.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_3312049_4	264732.Moth_1809	1.512e-244	769.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,42FTG@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459
MMS3_k127_3312049_1	264732.Moth_1810	0.0	1026.0	COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,42HS1@68295|Thermoanaerobacterales	186801|Clostridia	G	Domain of unknown function (DUF3536)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
MMS3_k127_3312049_2	880072.Desac_0214	1.485e-281	895.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,42MEW@68525|delta/epsilon subdivisions,2WJX1@28221|Deltaproteobacteria,2MQXA@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM alpha amylase, catalytic	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
MMS3_k127_3312049_13	525904.Tter_1585	1.438e-13	76.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
MMS3_k127_3312049_9	1128421.JAGA01000003_gene2879	1.751e-64	228.0	COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria	2|Bacteria	C	cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
MMS3_k127_3312049_3	1123242.JH636434_gene3641	4.45e-272	845.0	COG0843@1|root,COG0843@2|Bacteria,2IXCQ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
MMS3_k127_3312049_6	234267.Acid_0497	1.425e-110	365.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
MMS3_k127_3312049_8	234267.Acid_0496	5.686e-75	263.0	COG1999@1|root,COG1999@2|Bacteria,3Y3XH@57723|Acidobacteria	57723|Acidobacteria	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
MMS3_k127_3312049_12	1340493.JNIF01000004_gene147	3.484e-15	81.0	2EJZ3@1|root,33DPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3312049_7	1128421.JAGA01000003_gene2874	9.473e-101	340.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3312049_10	204669.Acid345_3000	9.154e-64	226.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria,2JI6T@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMS3_k127_3312049_11	661478.OP10G_2183	4.818e-63	220.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
MMS3_k127_3312049_5	1128421.JAGA01000003_gene2871	4.019e-199	630.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
MMS3_k127_3312049_0	1128421.JAGA01000003_gene2870	0.0	1114.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
MMS3_k127_3320283_0	204669.Acid345_3215	4.156e-128	426.0	COG0501@1|root,COG0501@2|Bacteria,3Y3FX@57723|Acidobacteria,2JHYR@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
MMS3_k127_3320283_1	1382359.JIAL01000001_gene2600	1.88e-34	147.0	COG0810@1|root,COG0810@2|Bacteria,3Y58J@57723|Acidobacteria,2JJPH@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
MMS3_k127_3320283_2	880072.Desac_2171	2.611e-29	124.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
MMS3_k127_3324749_7	485913.Krac_4635	1.41e-40	156.0	COG3408@1|root,COG3408@2|Bacteria,2G7KB@200795|Chloroflexi	200795|Chloroflexi	G	PFAM alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
MMS3_k127_3324749_1	234267.Acid_5762	9.346e-141	465.0	COG1139@1|root,COG1139@2|Bacteria,3Y3R8@57723|Acidobacteria	57723|Acidobacteria	C	cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
MMS3_k127_3324749_3	1196323.ALKF01000201_gene2851	5.085e-81	276.0	COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,26T56@186822|Paenibacillaceae	91061|Bacilli	C	Fe-S oxidoreductase	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
MMS3_k127_3324749_8	248742.XP_005645179.1	2.762e-11	68.0	COG1028@1|root,KOG0725@2759|Eukaryota,37J0M@33090|Viridiplantae	33090|Viridiplantae	Q	short-chain dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3324749_6	1267535.KB906767_gene3932	1.342e-59	222.0	COG1408@1|root,COG1408@2|Bacteria,3Y5PS@57723|Acidobacteria,2JP4E@204432|Acidobacteriia	204432|Acidobacteriia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
MMS3_k127_3324749_0	204669.Acid345_2559	2.158e-154	499.0	COG0477@1|root,COG2814@2|Bacteria,3Y2RQ@57723|Acidobacteria,2JHZK@204432|Acidobacteriia	204432|Acidobacteriia	EGP	PFAM Major facilitator superfamily	-	-	-	ko:K08178	-	-	-	-	ko00000,ko02000	2.A.1.12	-	-	Sugar_tr
MMS3_k127_3324749_5	204669.Acid345_4645	8.16e-60	220.0	COG0457@1|root,COG0457@2|Bacteria,3Y3BD@57723|Acidobacteria,2JHJR@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TPR_16,TPR_2
MMS3_k127_3324749_2	945713.IALB_0290	2.558e-92	310.0	COG0603@1|root,COG0603@2|Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
MMS3_k127_3324749_4	671143.DAMO_3114	9.281e-72	248.0	COG0602@1|root,COG0602@2|Bacteria,2NPEM@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100	-	R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
MMS3_k127_3326355_0	204669.Acid345_4676	0.0	2116.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria,2JIQM@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
MMS3_k127_3326355_1	204669.Acid345_4677	3.005e-45	167.0	COG0222@1|root,COG0222@2|Bacteria,3Y50J@57723|Acidobacteria,2JJHE@204432|Acidobacteriia	204432|Acidobacteriia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
MMS3_k127_3327109_0	1267535.KB906767_gene3744	1.641e-213	682.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,CBM-like,Glyco_hydro_38,Glyco_hydro_38C
MMS3_k127_3327109_2	1267535.KB906767_gene1722	1.653e-117	388.0	COG1028@1|root,COG1028@2|Bacteria,3Y7GE@57723|Acidobacteria,2JM48@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3327109_1	1088721.NSU_3180	1.601e-158	515.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,2KCQN@204457|Sphingomonadales	28211|Alphaproteobacteria	P	Domain of unknown function (DUF4976)	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
MMS3_k127_3327109_3	1123278.KB893499_gene388	1.304e-114	382.0	COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,47JHU@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMS3_k127_3329205_4	1267534.KB906754_gene2972	3.205e-06	51.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
MMS3_k127_3329205_5	1297865.APJD01000002_gene4114	1.182e-05	53.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,3JSZR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
MMS3_k127_3329205_1	1267535.KB906767_gene3888	2.731e-120	402.0	COG0642@1|root,COG2205@2|Bacteria,3Y2W3@57723|Acidobacteria,2JIDP@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
MMS3_k127_3329205_2	234267.Acid_0071	4.982e-85	290.0	COG0745@1|root,COG0745@2|Bacteria,3Y4Q8@57723|Acidobacteria	57723|Acidobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_3329205_0	1191523.MROS_1006	1.06e-260	823.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	ybaT	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009268,GO:0009628,GO:0010035,GO:0010038,GO:0016020,GO:0042221,GO:0044464,GO:0046688,GO:0050896,GO:0071944,GO:0097501,GO:1990169	-	ko:K03322,ko:K07076,ko:K09944,ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13,2.A.55.2.6,2.A.55.3	-	-	AA_permease_2,Usp
MMS3_k127_3329205_3	1191523.MROS_1007	1.263e-26	127.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_3336145_2	998674.ATTE01000001_gene2627	2.026e-24	106.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,45ZRV@72273|Thiotrichales	72273|Thiotrichales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
MMS3_k127_3336145_3	1267533.KB906736_gene1130	6.504e-06	51.0	COG1874@1|root,COG1874@2|Bacteria,3Y31W@57723|Acidobacteria,2JIYQ@204432|Acidobacteriia	204432|Acidobacteriia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_35,Glyco_hydro_42
MMS3_k127_3336145_1	1267535.KB906767_gene331	2.416e-131	436.0	COG5368@1|root,COG5368@2|Bacteria,3Y2MM@57723|Acidobacteria,2JI52@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
MMS3_k127_3336145_0	1382359.JIAL01000001_gene838	1.646e-213	694.0	COG3459@1|root,COG3459@2|Bacteria,3Y3E9@57723|Acidobacteria,2JHM2@204432|Acidobacteriia	204432|Acidobacteriia	G	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
MMS3_k127_3336649_2	760568.Desku_1709	2.221e-17	89.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,2605U@186807|Peptococcaceae	186801|Clostridia	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN,Polysacc_synt_3,Polysacc_synt_C
MMS3_k127_3336649_0	234267.Acid_4123	1.135e-51	201.0	COG3307@1|root,COG3307@2|Bacteria,3Y67G@57723|Acidobacteria	57723|Acidobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_3336649_1	234267.Acid_6760	6.933e-38	148.0	COG1399@1|root,COG1399@2|Bacteria,3Y4KJ@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
MMS3_k127_3341918_7	1184267.A11Q_79	2.659e-47	178.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3341918_1	1128427.KB904821_gene205	1.362e-177	576.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
MMS3_k127_3341918_5	243233.MCA0471	8.156e-78	283.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,1XGYK@135618|Methylococcales	135618|Methylococcales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_3341918_6	1125863.JAFN01000001_gene685	1.313e-70	248.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,43BKJ@68525|delta/epsilon subdivisions,2WIZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3341918_8	234267.Acid_2701	2.768e-33	143.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
MMS3_k127_3341918_9	485913.Krac_11387	8.698e-24	107.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	2_5_RNA_ligase2,CPDase
MMS3_k127_3341918_4	1267535.KB906767_gene2449	4.26e-100	335.0	COG0346@1|root,COG0346@2|Bacteria,3Y4RM@57723|Acidobacteria,2JJCV@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_3341918_0	1382359.JIAL01000001_gene859	8.714e-202	641.0	COG3011@1|root,COG3011@2|Bacteria,3Y78A@57723|Acidobacteria,2JKGF@204432|Acidobacteriia	204432|Acidobacteriia	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
MMS3_k127_3341918_2	926550.CLDAP_36400	9.356e-173	576.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
MMS3_k127_3341918_3	234267.Acid_3616	1.164e-166	533.0	COG0436@1|root,COG0436@2|Bacteria,3Y2TF@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_3345967_0	1125863.JAFN01000001_gene663	2.075e-193	612.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
MMS3_k127_3345967_3	357808.RoseRS_0947	1.498e-08	66.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2G7FA@200795|Chloroflexi,375SS@32061|Chloroflexia	32061|Chloroflexia	FP	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH,HD
MMS3_k127_3345967_1	485913.Krac_9227	2.177e-78	271.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
MMS3_k127_3345967_2	485913.Krac_9228	9.335e-60	210.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
MMS3_k127_3353332_9	204669.Acid345_2341	3.887e-55	207.0	COG0815@1|root,COG0815@2|Bacteria,3Y4FZ@57723|Acidobacteria,2JKVC@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
MMS3_k127_3353332_13	926566.Terro_3770	0.0002404	51.0	COG3147@1|root,COG3147@2|Bacteria,3Y98V@57723|Acidobacteria,2JP5C@204432|Acidobacteriia	204432|Acidobacteriia	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
MMS3_k127_3353332_6	1267535.KB906767_gene610	2.946e-95	320.0	COG0330@1|root,COG0330@2|Bacteria,3Y33E@57723|Acidobacteria,2JHPX@204432|Acidobacteriia	204432|Acidobacteriia	O	SMART band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMS3_k127_3353332_4	204669.Acid345_2529	2.775e-112	377.0	COG1030@1|root,COG1030@2|Bacteria,3Y31N@57723|Acidobacteria,2JHS7@204432|Acidobacteriia	204432|Acidobacteriia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
MMS3_k127_3353332_10	1267534.KB906759_gene1995	2.641e-49	196.0	COG0457@1|root,COG0457@2|Bacteria,3Y2VC@57723|Acidobacteria,2JHR2@204432|Acidobacteriia	204432|Acidobacteriia	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
MMS3_k127_3353332_11	1267535.KB906767_gene2408	6.522e-46	179.0	COG0457@1|root,COG0457@2|Bacteria,3Y5A8@57723|Acidobacteria,2JNC1@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
MMS3_k127_3353332_0	1267535.KB906767_gene2487	1.243e-218	707.0	COG0744@1|root,COG0744@2|Bacteria,3Y42I@57723|Acidobacteria,2JI7Q@204432|Acidobacteriia	57723|Acidobacteria	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
MMS3_k127_3353332_1	1340493.JNIF01000003_gene2993	3.429e-205	652.0	COG0442@1|root,COG0442@2|Bacteria,3Y329@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
MMS3_k127_3353332_8	240015.ACP_3435	2.197e-76	272.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	cdu2	-	-	ko:K05564,ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6,2.A.63.1	-	-	Na_H_Exchanger,Usp
MMS3_k127_3353332_5	926566.Terro_1521	1.528e-99	333.0	COG2107@1|root,COG2107@2|Bacteria,3Y31U@57723|Acidobacteria,2JIDE@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
MMS3_k127_3353332_7	671143.DAMO_0948	2.293e-89	309.0	COG0477@1|root,COG2814@2|Bacteria,2NQYI@2323|unclassified Bacteria	2|Bacteria	EGP	Sugar (and other) transporter	yajR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_3353332_3	1267533.KB906735_gene4867	2.149e-119	392.0	COG3391@1|root,COG3391@2|Bacteria,3Y2SU@57723|Acidobacteria,2JKB8@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
MMS3_k127_3353332_2	574087.Acear_0212	1.255e-201	642.0	COG0119@1|root,COG0119@2|Bacteria,1TRIK@1239|Firmicutes,249Q4@186801|Clostridia,3WACK@53433|Halanaerobiales	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMS3_k127_3394150_5	1313301.AUGC01000006_gene85	5.75e-20	90.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_3394150_4	1173264.KI913949_gene745	6.205e-58	212.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1H8P0@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
MMS3_k127_3394150_3	204669.Acid345_3436	2.794e-63	224.0	COG4122@1|root,COG4122@2|Bacteria,3Y4X9@57723|Acidobacteria,2JMCH@204432|Acidobacteriia	204432|Acidobacteriia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
MMS3_k127_3394150_0	1267535.KB906767_gene4918	6.855e-179	578.0	COG1233@1|root,COG1233@2|Bacteria,3Y9B4@57723|Acidobacteria	57723|Acidobacteria	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
MMS3_k127_3394150_1	1134912.AJTV01000037_gene2441	1.722e-165	527.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,3710S@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic,Fic_N,HTH_24
MMS3_k127_3394150_2	452637.Oter_4342	3.922e-144	466.0	COG1312@1|root,COG1312@2|Bacteria,46UDP@74201|Verrucomicrobia,3K8B6@414999|Opitutae	414999|Opitutae	G	Catalyzes the dehydration of D-mannonate	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
MMS3_k127_3400101_6	204669.Acid345_4302	4.663e-07	51.0	COG0346@1|root,COG0346@2|Bacteria,3Y8DH@57723|Acidobacteria,2JNIW@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
MMS3_k127_3400101_1	330214.NIDE2980	1.539e-156	499.0	COG1830@1|root,COG1830@2|Bacteria,3J1DE@40117|Nitrospirae	40117|Nitrospirae	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
MMS3_k127_3400101_4	234267.Acid_2964	1.177e-57	209.0	COG2930@1|root,COG2930@2|Bacteria,3Y6Q0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
MMS3_k127_3400101_2	1267535.KB906767_gene2323	3.994e-78	270.0	28J3W@1|root,2Z900@2|Bacteria,3Y47Q@57723|Acidobacteria	57723|Acidobacteria	S	pfam nipsnap	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
MMS3_k127_3400101_3	1267535.KB906767_gene2323	1.22e-72	254.0	28J3W@1|root,2Z900@2|Bacteria,3Y47Q@57723|Acidobacteria	57723|Acidobacteria	S	pfam nipsnap	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
MMS3_k127_3400101_5	477974.Daud_0494	2.353e-15	81.0	arCOG08693@1|root,339YK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3400101_0	1382359.JIAL01000001_gene892	6.974e-172	549.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria,2JIAE@204432|Acidobacteriia	204432|Acidobacteriia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS3_k127_3407016_2	247490.KSU1_C1363	1.268e-24	106.0	COG1071@1|root,COG1071@2|Bacteria,2IXGM@203682|Planctomycetes	203682|Planctomycetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMS3_k127_3407016_0	234267.Acid_0353	7.773e-156	496.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMS3_k127_3407016_1	234267.Acid_0914	1.145e-122	407.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_3419054_2	1267534.KB906755_gene4113	2.891e-76	280.0	2DMDG@1|root,32PV1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
MMS3_k127_3419054_1	880072.Desac_2196	3.945e-140	454.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,2MQS7@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
MMS3_k127_3419054_6	1169143.KB911037_gene3911	2.452e-19	98.0	COG2227@1|root,COG2227@2|Bacteria,1R0P8@1224|Proteobacteria,2WI0S@28216|Betaproteobacteria,1K6G7@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
MMS3_k127_3419054_0	1267534.KB906755_gene4114	2.129e-140	464.0	COG2244@1|root,COG2244@2|Bacteria,3Y5SE@57723|Acidobacteria,2JJXB@204432|Acidobacteriia	204432|Acidobacteriia	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3
MMS3_k127_3419054_4	1267534.KB906755_gene4116	3.487e-64	237.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
MMS3_k127_3419054_3	443144.GM21_3185	4.637e-70	249.0	COG1215@1|root,COG1215@2|Bacteria,1QN3N@1224|Proteobacteria	1224|Proteobacteria	M	glycosyl transferase family	exoM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16556	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
MMS3_k127_3419054_5	394221.Mmar10_1686	1.193e-39	159.0	COG0726@1|root,COG0726@2|Bacteria,1R881@1224|Proteobacteria,2U1Y9@28211|Alphaproteobacteria,43Y0H@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_3442810_0	1267535.KB906767_gene423	7.307e-132	425.0	COG1649@1|root,COG1649@2|Bacteria,3Y6SC@57723|Acidobacteria,2JM8G@204432|Acidobacteriia	204432|Acidobacteriia	S	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
MMS3_k127_3442810_1	509635.N824_20400	2.021e-70	248.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.21.96	ko:K01361,ko:K13277,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Amidase_2,Big_2,CBM_X2,DUF1983,DUF2961,Glucosaminidase,LRR_5,Laminin_G_3,PA,Peptidase_S8,Phage-tail_3,SLH,fn3_5
MMS3_k127_34767_1	1267535.KB906767_gene4432	1.257e-118	391.0	COG1629@1|root,COG1629@2|Bacteria,3Y620@57723|Acidobacteria,2JKZX@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_34767_2	401053.AciPR4_2731	2.537e-94	321.0	COG1609@1|root,COG1609@2|Bacteria,3Y6B3@57723|Acidobacteria,2JMEZ@204432|Acidobacteriia	204432|Acidobacteriia	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
MMS3_k127_34767_0	1267535.KB906767_gene4121	1.106e-240	764.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
MMS3_k127_3480788_3	1267535.KB906767_gene1432	7.099e-21	93.0	COG2835@1|root,COG2835@2|Bacteria,3Y8VE@57723|Acidobacteria	57723|Acidobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
MMS3_k127_3480788_2	401526.TcarDRAFT_0347	4.786e-36	151.0	COG0859@1|root,COG0859@2|Bacteria,1UZZI@1239|Firmicutes,4H2VC@909932|Negativicutes	909932|Negativicutes	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
MMS3_k127_3480788_1	671143.DAMO_0267	4.725e-63	228.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
MMS3_k127_3480788_4	1382359.JIAL01000001_gene622	2.669e-13	75.0	2B50C@1|root,31XTG@2|Bacteria,3Y4VH@57723|Acidobacteria,2JJMH@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3480788_0	1267535.KB906767_gene835	7.008e-92	308.0	COG1028@1|root,COG1028@2|Bacteria,3Y7BE@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3493448_3	344747.PM8797T_23049	1.042e-09	68.0	2CBIH@1|root,33WXG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3493448_1	861299.J421_0663	2.226e-93	311.0	COG1707@1|root,COG1707@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	ACT
MMS3_k127_3493448_2	472759.Nhal_1889	1.547e-52	192.0	COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,1T0ZH@1236|Gammaproteobacteria,1X0TI@135613|Chromatiales	135613|Chromatiales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_3493448_0	1267533.KB906739_gene2747	0.0	1221.0	COG4447@1|root,COG4447@2|Bacteria,3Y2SN@57723|Acidobacteria,2JIF7@204432|Acidobacteriia	204432|Acidobacteriia	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_3508121_2	234267.Acid_6488	1.936e-123	426.0	COG1629@1|root,COG4771@2|Bacteria,3Y7F9@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_3508121_1	234267.Acid_1002	1.081e-200	636.0	COG0457@1|root,COG0457@2|Bacteria,3Y69Y@57723|Acidobacteria	57723|Acidobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3508121_0	1382359.JIAL01000001_gene2689	1.578e-266	839.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3NT@57723|Acidobacteria,2JIBK@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
MMS3_k127_3508121_6	1267535.KB906767_gene3248	2.25e-54	203.0	COG1082@1|root,COG1082@2|Bacteria,3Y6ZA@57723|Acidobacteria	57723|Acidobacteria	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
MMS3_k127_3508121_4	1123261.AXDW01000002_gene1666	9.662e-109	365.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1X5GT@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
MMS3_k127_3508121_9	1382359.JIAL01000001_gene1466	3.08e-36	159.0	COG2982@1|root,COG2982@2|Bacteria,3Y3Z4@57723|Acidobacteria,2JIBU@204432|Acidobacteriia	204432|Acidobacteriia	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
MMS3_k127_3508121_5	240015.ACP_2039	1.388e-64	231.0	COG0681@1|root,COG0681@2|Bacteria,3Y40D@57723|Acidobacteria,2JHWM@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
MMS3_k127_3508121_7	1125863.JAFN01000001_gene557	1.173e-46	177.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
MMS3_k127_3508121_14	1340493.JNIF01000003_gene4495	9.283e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,3Y5WJ@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3508121_3	401053.AciPR4_1260	3.039e-117	392.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_3508121_8	1267535.KB906767_gene290	1.107e-45	176.0	COG2948@1|root,COG2948@2|Bacteria,3Y6SY@57723|Acidobacteria	57723|Acidobacteria	U	multi-organism process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3508121_10	240015.ACP_2938	5.035e-27	112.0	2BYAI@1|root,315Y9@2|Bacteria,3Y52S@57723|Acidobacteria,2JJJK@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3508121_11	452637.Oter_0807	3.822e-26	113.0	COG2010@1|root,COG2010@2|Bacteria,46TBB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
MMS3_k127_3508121_12	292459.STH2474	6.029e-15	83.0	COG1266@1|root,COG1266@2|Bacteria,1VHVC@1239|Firmicutes	1239|Firmicutes	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
MMS3_k127_3508121_13	761193.Runsl_0007	5.788e-13	69.0	28HIE@1|root,2Z7TW@2|Bacteria,4NJBE@976|Bacteroidetes,47M5B@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3520061_5	240015.ACP_3283	1.721e-35	138.0	COG3669@1|root,COG3669@2|Bacteria,3Y36K@57723|Acidobacteria,2JIX7@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-fucosidase C-terminal domain	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
MMS3_k127_3520061_1	1303518.CCALI_01938	1.347e-128	430.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	fucA1	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
MMS3_k127_3520061_0	1267535.KB906767_gene4851	2.821e-174	559.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
MMS3_k127_3520061_6	1123269.NX02_17325	4.27e-17	85.0	COG2721@1|root,COG2721@2|Bacteria,1NASV@1224|Proteobacteria,2UGED@28211|Alphaproteobacteria,2K719@204457|Sphingomonadales	204457|Sphingomonadales	G	SAF	-	-	-	-	-	-	-	-	-	-	-	-	SAF
MMS3_k127_3520061_2	583355.Caka_0518	1.441e-127	419.0	COG2721@1|root,COG2721@2|Bacteria,46UHM@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM D-galactarate dehydratase Altronate hydrolase domain protein	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
MMS3_k127_3520061_3	1380391.JIAS01000011_gene4706	2.926e-89	302.0	COG3618@1|root,COG3618@2|Bacteria,1P5PT@1224|Proteobacteria,2U3BR@28211|Alphaproteobacteria,2JTDV@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_3520061_4	1267535.KB906767_gene5162	2.998e-39	147.0	COG3254@1|root,COG3254@2|Bacteria,3Y5KE@57723|Acidobacteria,2JNUN@204432|Acidobacteriia	57723|Acidobacteria	S	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
MMS3_k127_3558106_1	1267533.KB906734_gene3899	4.917e-19	101.0	2DXMA@1|root,345IN@2|Bacteria,3Y8DJ@57723|Acidobacteria,2JNF0@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3558106_3	1304875.JAFZ01000001_gene826	2.784e-05	57.0	2DPUT@1|root,333G8@2|Bacteria,3TBKX@508458|Synergistetes	508458|Synergistetes	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234,zinc_ribbon_2
MMS3_k127_3558106_0	1267534.KB906754_gene2813	5.117e-43	173.0	2A5Z5@1|root,30URA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
MMS3_k127_355980_1	195253.Syn6312_0213	1.057e-65	231.0	COG0518@1|root,COG0518@2|Bacteria,1G5SC@1117|Cyanobacteria,1GZE5@1129|Synechococcus	1117|Cyanobacteria	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
MMS3_k127_355980_3	1384054.N790_01760	1.473e-41	158.0	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,1RR6A@1236|Gammaproteobacteria,1X6KZ@135614|Xanthomonadales	135614|Xanthomonadales	M	acetyltransferase	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
MMS3_k127_355980_4	42256.RradSPS_2764	5.147e-20	95.0	COG3071@1|root,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	hemY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_2
MMS3_k127_355980_0	1382359.JIAL01000001_gene579	2.233e-79	274.0	COG1611@1|root,COG1611@2|Bacteria,3Y2MR@57723|Acidobacteria,2JHUP@204432|Acidobacteriia	204432|Acidobacteriia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMS3_k127_355980_2	1340493.JNIF01000003_gene2784	6.714e-45	170.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_3575101_1	404589.Anae109_4490	1.604e-64	235.0	COG0520@1|root,COG0520@2|Bacteria,1QU0N@1224|Proteobacteria,42YS3@68525|delta/epsilon subdivisions,2WU59@28221|Deltaproteobacteria,2YTT1@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_3575101_2	1267533.KB906737_gene1604	1.106e-23	107.0	COG0454@1|root,COG0456@2|Bacteria,3Y5GV@57723|Acidobacteria,2JJZU@204432|Acidobacteriia	204432|Acidobacteriia	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
MMS3_k127_3575101_0	234267.Acid_2705	1.22e-221	713.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_3583926_0	1408473.JHXO01000001_gene1972	2.877e-259	829.0	COG2133@1|root,COG3391@1|root,COG3511@1|root,COG2133@2|Bacteria,COG3391@2|Bacteria,COG3511@2|Bacteria,4NER2@976|Bacteroidetes,2FQ0E@200643|Bacteroidia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3583926_1	234267.Acid_5940	2.898e-122	412.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMS3_k127_3595410_1	1415779.JOMH01000001_gene2856	2.555e-30	122.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,1S9WR@1236|Gammaproteobacteria,1X7YI@135614|Xanthomonadales	135614|Xanthomonadales	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
MMS3_k127_3595410_2	269799.Gmet_2972	6.1e-30	121.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WRF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
MMS3_k127_3595410_0	1267535.KB906767_gene361	8.995e-134	440.0	COG0673@1|root,COG0673@2|Bacteria,3Y6Q3@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_3644621_0	234267.Acid_7763	1.02e-224	717.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria	57723|Acidobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
MMS3_k127_3644621_2	234267.Acid_5783	9.769e-103	355.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_3644621_1	204669.Acid345_2904	3.562e-201	640.0	COG1215@1|root,COG1215@2|Bacteria,3Y31I@57723|Acidobacteria,2JIKW@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
MMS3_k127_3644621_3	426117.M446_4899	7.887e-27	120.0	COG1216@1|root,COG1216@2|Bacteria,1R06Z@1224|Proteobacteria,2VGUR@28211|Alphaproteobacteria,1JUBY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS3_k127_3664350_2	278963.ATWD01000001_gene3188	6.134e-44	162.0	COG0112@1|root,COG0112@2|Bacteria,3Y2JB@57723|Acidobacteria,2JI87@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
MMS3_k127_3664350_0	240015.ACP_0812	9.344e-77	274.0	COG3349@1|root,COG3349@2|Bacteria,3Y3PB@57723|Acidobacteria,2JIW6@204432|Acidobacteriia	204432|Acidobacteriia	C	FAD dependent oxidoreductase	-	-	1.3.5.6	ko:K00514	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04798,R04800,R07511,R09656,R09658	RC01214,RC01959	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMS3_k127_3664350_1	1123368.AUIS01000001_gene2032	1.245e-68	244.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,1S3EY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Squalene/phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
MMS3_k127_3723271_0	1267535.KB906767_gene2552	1.286e-199	630.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria,2JMMF@204432|Acidobacteriia	204432|Acidobacteriia	M	Tricorn protease PDZ domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
MMS3_k127_3811446_2	167555.NATL1_00731	3.129e-24	117.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1GMXH@1117|Cyanobacteria,1MNCP@1212|Prochloraceae	1117|Cyanobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_8
MMS3_k127_3811446_1	234267.Acid_7539	1.199e-33	133.0	COG0724@1|root,COG0724@2|Bacteria,3Y59V@57723|Acidobacteria	57723|Acidobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMS3_k127_3811446_0	1313304.CALK_1497	2.246e-118	391.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_3822864_3	204669.Acid345_1020	7.702e-62	218.0	COG0448@1|root,COG0448@2|Bacteria,3Y35M@57723|Acidobacteria,2JIZF@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_3822864_0	204669.Acid345_4602	2.004e-134	438.0	COG0232@1|root,COG0232@2|Bacteria,3Y2S2@57723|Acidobacteria,2JIHE@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
MMS3_k127_3822864_1	330214.NIDE4168	2.049e-121	410.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria,3J0Y7@40117|Nitrospirae	40117|Nitrospirae	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
MMS3_k127_3822864_2	525897.Dbac_0762	1.538e-82	291.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2M7ZK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMS3_k127_3822864_4	1492737.FEM08_36160	5.7e-39	150.0	COG3507@1|root,COG3507@2|Bacteria,4PKZY@976|Bacteroidetes,1HZ0G@117743|Flavobacteriia,2NV00@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
MMS3_k127_3832394_3	1382359.JIAL01000001_gene2530	4.398e-35	135.0	COG1201@1|root,COG1201@2|Bacteria,3Y348@57723|Acidobacteria,2JIVQ@204432|Acidobacteriia	204432|Acidobacteriia	L	dead deah	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMS3_k127_3832394_2	575540.Isop_2265	2.849e-57	212.0	COG1305@1|root,COG1305@2|Bacteria,2IYAD@203682|Planctomycetes	203682|Planctomycetes	E	transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
MMS3_k127_3832394_1	118163.Ple7327_1203	2.926e-73	259.0	COG2307@1|root,COG2307@2|Bacteria,1G05F@1117|Cyanobacteria,3VIVV@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Bacterial domain of	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
MMS3_k127_3832394_0	1303518.CCALI_00998	5.734e-181	578.0	COG2308@1|root,COG2308@2|Bacteria	2|Bacteria	S	glutamate-cysteine ligase activity	gcs2	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_1,CP_ATPgrasp_2
MMS3_k127_3832394_4	525904.Tter_0923	1.001e-24	119.0	COG0582@1|root,COG0582@2|Bacteria,2NRA8@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	int	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS3_k127_3839625_3	1121957.ATVL01000008_gene4432	1.566e-70	252.0	COG1874@1|root,COG1874@2|Bacteria,4NE2P@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 35 family	-	-	-	-	-	-	-	-	-	-	-	-	BetaGal_dom2,Glyco_hydro_35
MMS3_k127_3839625_2	794903.OPIT5_15610	9.216e-81	296.0	COG3250@1|root,COG3250@2|Bacteria,46Y7Z@74201|Verrucomicrobia,3K934@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
MMS3_k127_3839625_4	682795.AciX8_3516	1.321e-67	237.0	COG2197@1|root,COG2197@2|Bacteria,3Y4RP@57723|Acidobacteria,2JKVK@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_3839625_1	234267.Acid_2684	5.798e-221	721.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,3Y2FS@57723|Acidobacteria	57723|Acidobacteria	T	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,Y_Y_Y
MMS3_k127_3839625_0	349163.Acry_0895	8.83e-308	972.0	COG3391@1|root,COG3391@2|Bacteria,1R6BZ@1224|Proteobacteria,2U2WX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
MMS3_k127_3839625_5	1262915.BN574_01532	1.91e-08	60.0	COG3875@1|root,COG3875@2|Bacteria,1VUKE@1239|Firmicutes,4H7HX@909932|Negativicutes	909932|Negativicutes	S	lactate racemase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3857106_1	234267.Acid_7677	2.811e-65	231.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
MMS3_k127_3857106_2	1121413.JMKT01000001_gene1686	9.997e-35	138.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2X245@28221|Deltaproteobacteria,2MFSC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMS3_k127_3857106_0	580332.Slit_2572	2.01e-74	256.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3859054_0	234267.Acid_6983	4.999e-137	444.0	COG0136@1|root,COG0136@2|Bacteria,3Y346@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMS3_k127_3859054_3	234267.Acid_6981	7.259e-64	226.0	COG0289@1|root,COG0289@2|Bacteria,3Y50R@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
MMS3_k127_3859054_2	234267.Acid_6980	1.159e-102	343.0	COG0329@1|root,COG0329@2|Bacteria,3Y3V8@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_3859054_1	1267535.KB906767_gene2122	3.52e-114	374.0	COG2171@1|root,COG2171@2|Bacteria,3Y2Z3@57723|Acidobacteria,2JIDV@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_N_2
MMS3_k127_3859054_4	1232410.KI421412_gene336	1.297e-19	89.0	29SGJ@1|root,2ZKKB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3859054_5	1146883.BLASA_2870	6.493e-10	63.0	2C59E@1|root,2ZDAY@2|Bacteria	2|Bacteria	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS3_k127_3861944_7	1196324.A374_13215	0.0001496	44.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,4HDII@91061|Bacilli	91061|Bacilli	S	ABC transporter (Permease	M1-957	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
MMS3_k127_3861944_3	713587.THITH_03715	9.142e-27	110.0	COG2442@1|root,COG2442@2|Bacteria,1N96I@1224|Proteobacteria,1SHY0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
MMS3_k127_3861944_4	1123399.AQVE01000001_gene562	2.892e-14	75.0	COG4634@1|root,COG4634@2|Bacteria,1N9QC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
MMS3_k127_3861944_1	595460.RRSWK_06956	2.852e-99	336.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K18831,ko:K21498	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,HTH_31,Peptidase_M78
MMS3_k127_3861944_2	882378.RBRH_01177	9.697e-32	130.0	2CV9G@1|root,32SX7@2|Bacteria,1N1QV@1224|Proteobacteria,2VXDN@28216|Betaproteobacteria,1KBG0@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3861944_6	671143.DAMO_1330	2.676e-09	62.0	2EUJ6@1|root,33N15@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3861944_0	240015.ACP_3127	3.96e-157	504.0	COG0082@1|root,COG0082@2|Bacteria,3Y2Z8@57723|Acidobacteria,2JINW@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
MMS3_k127_3861944_5	1163409.UUA_00325	2.574e-10	64.0	COG3391@1|root,COG3391@2|Bacteria,1R9A0@1224|Proteobacteria,1S4GC@1236|Gammaproteobacteria,1X55E@135614|Xanthomonadales	135614|Xanthomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3866989_0	1267534.KB906760_gene1597	4.005e-51	184.0	COG0756@1|root,COG0756@2|Bacteria,3Y5NF@57723|Acidobacteria,2JK1V@204432|Acidobacteriia	204432|Acidobacteriia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	-	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
MMS3_k127_3866989_1	583345.Mmol_1191	1.3e-38	149.0	COG2731@1|root,COG2731@2|Bacteria,1RJ5F@1224|Proteobacteria,2VTSG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
MMS3_k127_38685_6	639030.JHVA01000001_gene3949	5.895e-52	191.0	2E19M@1|root,2ZCDB@2|Bacteria,3Y4DH@57723|Acidobacteria,2JJ2T@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_38685_12	385682.AFSL01000008_gene2603	9.492e-13	74.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,3XK7D@558415|Marinilabiliaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMS3_k127_38685_5	1340493.JNIF01000003_gene2685	5.919e-68	240.0	COG1475@1|root,COG1475@2|Bacteria,3Y40Y@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
MMS3_k127_38685_2	234267.Acid_0016	3.271e-101	336.0	COG1192@1|root,COG1192@2|Bacteria,3Y2Y2@57723|Acidobacteria	57723|Acidobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMS3_k127_38685_10	401053.AciPR4_4153	1.187e-33	139.0	COG0357@1|root,COG0357@2|Bacteria,3Y4W7@57723|Acidobacteria,2JJG7@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
MMS3_k127_38685_3	497964.CfE428DRAFT_4312	2.023e-91	311.0	COG1994@1|root,COG1994@2|Bacteria,46VEB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
MMS3_k127_38685_8	234267.Acid_5591	4.924e-40	156.0	COG1845@1|root,COG1845@2|Bacteria,3Y2KJ@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
MMS3_k127_38685_4	1267535.KB906767_gene1277	2.498e-84	289.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria,2JIRB@204432|Acidobacteriia	204432|Acidobacteriia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
MMS3_k127_38685_9	1254432.SCE1572_38930	2.406e-34	136.0	COG2322@1|root,COG2322@2|Bacteria,1N3YI@1224|Proteobacteria,430G9@68525|delta/epsilon subdivisions,2WVW0@28221|Deltaproteobacteria,2YV26@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
MMS3_k127_38685_13	545276.KB898725_gene666	1.786e-09	65.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,1X154@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
MMS3_k127_38685_11	234267.Acid_5312	1.58e-27	113.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
MMS3_k127_38685_1	1173024.KI912149_gene5493	8.056e-269	844.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,1JK2F@1189|Stigonemataceae	1117|Cyanobacteria	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
MMS3_k127_38685_0	671143.DAMO_0621	0.0	1344.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
MMS3_k127_38685_7	1267534.KB906757_gene1028	2.961e-44	165.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_3871241_3	204669.Acid345_4301	1.89e-38	147.0	COG1846@1|root,COG1846@2|Bacteria,3Y97P@57723|Acidobacteria,2JNFY@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMS3_k127_3871241_0	1267535.KB906767_gene4234	5.116e-202	639.0	COG0673@1|root,COG0673@2|Bacteria,3Y6RB@57723|Acidobacteria,2JKWU@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_3871241_2	935948.KE386495_gene1929	1.182e-53	199.0	COG1082@1|root,COG1082@2|Bacteria,1UZYH@1239|Firmicutes,24I07@186801|Clostridia,42IHM@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_3871241_4	187272.Mlg_1220	3.097e-18	90.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1T1K1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	CBS domain	hrp1	-	-	-	-	-	-	-	-	-	-	-	CBS
MMS3_k127_3871241_1	240015.ACP_0082	2.003e-124	410.0	COG0038@1|root,COG0038@2|Bacteria,3Y2G4@57723|Acidobacteria,2JIJC@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
MMS3_k127_3872213_4	234267.Acid_4250	9.192e-88	304.0	COG0644@1|root,COG0644@2|Bacteria,3Y5JJ@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Pyr_redox_2
MMS3_k127_3872213_1	1200792.AKYF01000009_gene3002	6.319e-172	549.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,26QYR@186822|Paenibacillaceae	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS08395	Aminotran_3
MMS3_k127_3872213_3	338966.Ppro_2692	1.526e-108	366.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
MMS3_k127_3872213_9	1267535.KB906767_gene1384	1.339e-23	106.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
MMS3_k127_3872213_5	1267533.KB906738_gene2056	2.7e-65	234.0	COG2064@1|root,COG2064@2|Bacteria,3Y4FI@57723|Acidobacteria,2JJ6X@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
MMS3_k127_3872213_6	1267535.KB906767_gene1386	2.149e-61	224.0	COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria,2JJ91@204432|Acidobacteriia	204432|Acidobacteriia	U	Type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
MMS3_k127_3872213_0	240015.ACP_1108	1.188e-174	557.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria,2JHVJ@204432|Acidobacteriia	204432|Acidobacteriia	U	secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
MMS3_k127_3872213_8	756272.Plabr_1526	4.693e-36	152.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,2IYFX@203682|Planctomycetes	203682|Planctomycetes	KTU	Flp pilus assembly protein, ATPase CpaE	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,Response_reg
MMS3_k127_3872213_2	1267535.KB906767_gene1378	1.34e-113	382.0	COG4964@1|root,COG4964@2|Bacteria,3Y3DF@57723|Acidobacteria,2JHJ6@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
MMS3_k127_3872213_7	234267.Acid_1409	2.248e-48	184.0	COG3745@1|root,COG3745@2|Bacteria,3Y4HR@57723|Acidobacteria	57723|Acidobacteria	U	PFAM SAF domain	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
MMS3_k127_3874389_1	608538.HTH_1822	1.503e-28	122.0	COG1502@1|root,COG1502@2|Bacteria,2G44G@200783|Aquificae	200783|Aquificae	I	SMART phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
MMS3_k127_3874389_0	1301098.PKB_3068	1.015e-274	867.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,1MVPR@1224|Proteobacteria,1RRTD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	estB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_38992_2	234267.Acid_3160	2.051e-55	198.0	COG0536@1|root,COG0536@2|Bacteria,3Y2J7@57723|Acidobacteria	57723|Acidobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
MMS3_k127_38992_3	204669.Acid345_0021	2.787e-46	175.0	COG1057@1|root,COG1057@2|Bacteria,3Y5D2@57723|Acidobacteria,2JJNT@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS3_k127_38992_4	204669.Acid345_0022	2.556e-31	126.0	COG0799@1|root,COG0799@2|Bacteria,3Y5SD@57723|Acidobacteria,2JJ9Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
MMS3_k127_38992_5	269799.Gmet_3202	8.409e-26	112.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria,43UX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
MMS3_k127_38992_1	204669.Acid345_4702	2.341e-80	271.0	COG2109@1|root,COG2109@2|Bacteria,3Y4DE@57723|Acidobacteria,2JJ2Y@204432|Acidobacteriia	204432|Acidobacteriia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
MMS3_k127_38992_0	204669.Acid345_4701	7.169e-111	366.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria,2JI81@204432|Acidobacteriia	204432|Acidobacteriia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMS3_k127_3912707_0	1267535.KB906767_gene4274	9.864e-180	572.0	COG2706@1|root,COG2706@2|Bacteria,3Y612@57723|Acidobacteria	57723|Acidobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
MMS3_k127_3912707_1	204669.Acid345_2396	1.18e-83	291.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TIG,Transglut_core
MMS3_k127_3912707_2	234267.Acid_4026	3.936e-14	75.0	2C5I9@1|root,33FY2@2|Bacteria,3Y5UQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3912707_4	1267535.KB906767_gene2165	7.774e-05	45.0	COG0591@1|root,COG0591@2|Bacteria,3Y3G7@57723|Acidobacteria,2JIY5@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
MMS3_k127_3917264_4	196367.JNFG01000011_gene6012	2.807e-57	205.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,1K3KP@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS3_k127_3917264_1	204669.Acid345_0583	1.773e-114	402.0	COG0457@1|root,COG2199@1|root,COG2203@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	MA20_13010	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,Lactamase_B_2,PAS_4
MMS3_k127_3917264_0	1382359.JIAL01000001_gene807	2.705e-291	903.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
MMS3_k127_3917264_2	1267535.KB906767_gene1009	1.93e-66	239.0	COG1266@1|root,COG1266@2|Bacteria,3Y4Q7@57723|Acidobacteria,2JJ77@204432|Acidobacteriia	204432|Acidobacteriia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_3917264_3	1499967.BAYZ01000147_gene697	2.994e-59	208.0	COG1839@1|root,COG1839@2|Bacteria,2NPAQ@2323|unclassified Bacteria	2|Bacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
MMS3_k127_3923910_1	1047013.AQSP01000043_gene53	5.87e-83	280.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMS3_k127_3923910_3	697282.Mettu_0544	5.553e-34	134.0	COG3439@1|root,COG3439@2|Bacteria,1RHJQ@1224|Proteobacteria,1S5ZG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
MMS3_k127_3923910_2	1267533.KB906735_gene5073	1.251e-56	209.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria,2JK7Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
MMS3_k127_3923910_0	471854.Dfer_4373	1.879e-115	381.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMS3_k127_3924683_1	1267535.KB906767_gene5447	9.423e-113	367.0	COG2303@1|root,COG2303@2|Bacteria,3Y6UA@57723|Acidobacteria	57723|Acidobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMS3_k127_3924683_13	478741.JAFS01000002_gene410	0.0002104	51.0	2CK2Q@1|root,329IJ@2|Bacteria,46ZCM@74201|Verrucomicrobia,37GU0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3924683_5	234267.Acid_5255	2.419e-52	197.0	2B11W@1|root,31TFA@2|Bacteria,3Y4Z8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3924683_7	1232410.KI421413_gene484	5.788e-38	146.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,437CT@68525|delta/epsilon subdivisions,2XA0U@28221|Deltaproteobacteria,43VKC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
MMS3_k127_3924683_2	1340493.JNIF01000003_gene3102	4.954e-112	369.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
MMS3_k127_3924683_3	880073.Calab_1751	1.502e-72	254.0	COG3264@1|root,COG3264@2|Bacteria,2NPZR@2323|unclassified Bacteria	2|Bacteria	M	Mechanosensitive ion channel	kefA	-	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	MS_channel
MMS3_k127_3924683_12	1296990.H845_3184	9.613e-05	48.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,2UFJJ@28211|Alphaproteobacteria,2JTVG@204441|Rhodospirillales	204441|Rhodospirillales	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
MMS3_k127_3924683_4	204669.Acid345_1299	6.679e-56	204.0	COG0356@1|root,COG0356@2|Bacteria,3Y4CM@57723|Acidobacteria,2JJ5W@204432|Acidobacteriia	204432|Acidobacteriia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
MMS3_k127_3924683_8	1198114.AciX9_2413	2.04e-25	109.0	COG0636@1|root,COG0636@2|Bacteria,3Y5G6@57723|Acidobacteria,2JJZ6@204432|Acidobacteriia	204432|Acidobacteriia	P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
MMS3_k127_3924683_9	1122613.ATUP01000001_gene234	8.024e-15	80.0	COG2022@1|root,COG2022@2|Bacteria,1QYPA@1224|Proteobacteria,2TXU5@28211|Alphaproteobacteria,440TJ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
MMS3_k127_3924683_0	204669.Acid345_4032	2.723e-115	387.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria,2JHT4@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,His_kinase
MMS3_k127_3924683_11	760568.Desku_0323	3.822e-07	57.0	COG0599@1|root,COG0599@2|Bacteria,1VFY0@1239|Firmicutes,25CIE@186801|Clostridia,2631D@186807|Peptococcaceae	186801|Clostridia	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_3924683_6	391625.PPSIR1_17125	1.92e-45	180.0	COG0477@1|root,COG2814@2|Bacteria,1PATR@1224|Proteobacteria,437WJ@68525|delta/epsilon subdivisions,2WYPZ@28221|Deltaproteobacteria,2YUGK@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	mmrA	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_3924908_3	1210884.HG799463_gene9569	1.413e-18	90.0	COG3356@1|root,COG3356@2|Bacteria,2IXKA@203682|Planctomycetes	203682|Planctomycetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
MMS3_k127_3924908_1	1088721.NSU_3180	5.532e-167	539.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,2KCQN@204457|Sphingomonadales	28211|Alphaproteobacteria	P	Domain of unknown function (DUF4976)	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
MMS3_k127_3924908_0	156889.Mmc1_1605	2.677e-194	631.0	COG3347@1|root,COG4221@1|root,COG3347@2|Bacteria,COG4221@2|Bacteria,1QVWU@1224|Proteobacteria,2TWVU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
MMS3_k127_3924908_2	1121015.N789_12710	5.678e-22	98.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1X3J3@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
MMS3_k127_3927024_0	204669.Acid345_4521	4.343e-113	374.0	COG1921@1|root,COG1921@2|Bacteria,3Y39V@57723|Acidobacteria,2JKCB@204432|Acidobacteriia	204432|Acidobacteriia	E	Selenocysteine synthase N terminal	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
MMS3_k127_3927024_1	1267535.KB906767_gene5075	4.978e-41	157.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	fur	-	-	ko:K03711,ko:K09823,ko:K09825	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
MMS3_k127_3927024_2	204669.Acid345_1870	5.513e-07	51.0	COG0672@1|root,COG0672@2|Bacteria,3Y3XB@57723|Acidobacteria,2JI3D@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Iron permease FTR1	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318,FTR1
MMS3_k127_3932423_2	234267.Acid_3965	1.807e-18	100.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Beta_helix,CUB,Calx-beta,DUF3739,Haemagg_act,SdrD_B
MMS3_k127_3932423_1	1391647.AVSV01000022_gene2477	2.529e-68	263.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,36DBS@31979|Clostridiaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
MMS3_k127_3932423_0	584708.Apau_0054	6.379e-115	395.0	COG2984@1|root,COG2984@2|Bacteria,3TBSS@508458|Synergistetes	508458|Synergistetes	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
MMS3_k127_3932423_3	794903.OPIT5_07145	3.835e-13	72.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
MMS3_k127_3932554_0	1121957.ATVL01000007_gene1566	2.257e-276	878.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,47J9V@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
MMS3_k127_3932554_1	525904.Tter_2460	3.974e-73	256.0	COG1349@1|root,COG1349@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	agaR	-	-	ko:K02081,ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
MMS3_k127_3934982_2	278963.ATWD01000001_gene1500	1.92e-105	347.0	COG1060@1|root,COG1060@2|Bacteria,3Y331@57723|Acidobacteria,2JITB@204432|Acidobacteriia	204432|Acidobacteriia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
MMS3_k127_3934982_13	1267535.KB906767_gene4265	1.263e-14	77.0	2FHRB@1|root,349IU@2|Bacteria,3Y8GP@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3934982_4	1382359.JIAL01000001_gene2314	2.817e-97	326.0	COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria,2JIHD@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
MMS3_k127_3934982_12	471852.Tcur_3882	4.492e-18	93.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4EHUG@85012|Streptosporangiales	201174|Actinobacteria	K	Uncharacterized ACR, COG1678	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
MMS3_k127_3934982_8	204669.Acid345_4517	3.384e-81	282.0	COG1463@1|root,COG1463@2|Bacteria,3Y3SX@57723|Acidobacteria,2JIP6@204432|Acidobacteriia	204432|Acidobacteriia	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
MMS3_k127_3934982_9	204669.Acid345_2891	5.25e-75	261.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
MMS3_k127_3934982_6	234267.Acid_0582	5.012e-87	294.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria	57723|Acidobacteria	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
MMS3_k127_3934982_10	1382359.JIAL01000001_gene3047	2.348e-74	259.0	COG4464@1|root,COG4464@2|Bacteria,3Y4AS@57723|Acidobacteria,2JJ14@204432|Acidobacteriia	204432|Acidobacteriia	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
MMS3_k127_3934982_11	639030.JHVA01000001_gene3323	8.461e-19	91.0	2CGTB@1|root,343WT@2|Bacteria,3Y8D9@57723|Acidobacteria,2JNEN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3934982_0	1379698.RBG1_1C00001G0688	1.951e-213	679.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
MMS3_k127_3934982_3	1267534.KB906754_gene3348	6.095e-105	348.0	COG0300@1|root,COG0300@2|Bacteria,3Y4AK@57723|Acidobacteria	57723|Acidobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3934982_1	1380394.JADL01000003_gene4961	9.715e-124	404.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,2JP95@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS3_k127_3934982_7	1121918.ARWE01000001_gene3175	5.041e-87	291.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42M21@68525|delta/epsilon subdivisions,2WK4G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
MMS3_k127_3934982_5	933262.AXAM01000015_gene69	9.361e-93	308.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42M21@68525|delta/epsilon subdivisions,2WK4G@28221|Deltaproteobacteria,2MKV8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
MMS3_k127_3935173_0	404589.Anae109_3071	1.188e-113	376.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,42PE5@68525|delta/epsilon subdivisions,2WK7C@28221|Deltaproteobacteria,2YU9Z@29|Myxococcales	28221|Deltaproteobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
MMS3_k127_3935173_1	1340493.JNIF01000003_gene1688	1.647e-61	217.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3944527_3	1267535.KB906767_gene1558	2.276e-27	112.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria,2JIG8@204432|Acidobacteriia	204432|Acidobacteriia	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
MMS3_k127_3944527_1	237368.SCABRO_00762	7.354e-67	239.0	28I4Y@1|root,2Z88D@2|Bacteria,2J2FV@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3944527_2	1173024.KI912148_gene4370	2.459e-34	135.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Ferric_reduct,Rieske,Rieske_2
MMS3_k127_3944527_5	1123278.KB893603_gene1843	2.396e-15	88.0	COG4783@1|root,COG4783@2|Bacteria,4NHD8@976|Bacteroidetes,47JAG@768503|Cytophagia	976|Bacteroidetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
MMS3_k127_3944527_0	986075.CathTA2_1452	4.049e-113	372.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,4H9SW@91061|Bacilli	91061|Bacilli	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
MMS3_k127_3944527_6	1033810.HLPCO_002949	1.539e-14	78.0	COG2128@1|root,COG2128@2|Bacteria,2NS09@2323|unclassified Bacteria	2|Bacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_3944527_4	926550.CLDAP_02880	4.216e-18	87.0	COG2128@1|root,COG2128@2|Bacteria,2G7D8@200795|Chloroflexi	200795|Chloroflexi	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_395308_3	518766.Rmar_1007	3.719e-39	157.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1FJR9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_395308_2	204669.Acid345_2941	1.283e-46	179.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria,2JK6C@204432|Acidobacteriia	204432|Acidobacteriia	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_395308_0	1121019.AUMN01000032_gene3082	2.416e-76	276.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,1W8V7@1268|Micrococcaceae	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,Sulfatase
MMS3_k127_395308_1	797209.ZOD2009_13491	1.133e-69	246.0	COG0580@1|root,arCOG04431@2157|Archaea,2XT1N@28890|Euryarchaeota,23YGU@183963|Halobacteria	183963|Halobacteria	G	Major intrinsic protein	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
MMS3_k127_395308_4	1191523.MROS_1976	7.359e-24	104.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
MMS3_k127_3987067_4	234267.Acid_4177	3.257e-19	101.0	COG3137@1|root,COG3137@2|Bacteria,3Y380@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
MMS3_k127_3987067_3	682795.AciX8_2362	3.166e-63	224.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria,2JN06@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
MMS3_k127_3987067_1	204669.Acid345_2474	1.14e-125	447.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
MMS3_k127_3987067_5	1267534.KB906754_gene3069	2.004e-13	79.0	COG0760@1|root,COG0760@2|Bacteria,3Y4KY@57723|Acidobacteria,2JJDJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
MMS3_k127_3987067_0	204669.Acid345_2476	1.189e-171	575.0	COG0729@1|root,COG4775@1|root,COG0729@2|Bacteria,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
MMS3_k127_3987067_2	1210884.HG799463_gene9554	5.065e-64	229.0	COG2120@1|root,COG2120@2|Bacteria,2IYPC@203682|Planctomycetes	203682|Planctomycetes	S	LmbE homologs	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_3987067_6	204669.Acid345_1594	4.342e-12	71.0	COG0457@1|root,COG0457@2|Bacteria,3Y4VN@57723|Acidobacteria,2JJG5@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
MMS3_k127_3991034_9	583345.Mmol_0780	2.304e-08	63.0	COG2197@1|root,COG2197@2|Bacteria,1N8MU@1224|Proteobacteria,2VV2P@28216|Betaproteobacteria,2KMXU@206350|Nitrosomonadales	206350|Nitrosomonadales	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
MMS3_k127_3991034_6	227882.SAV_5406	3.617e-36	151.0	COG3468@1|root,COG3468@2|Bacteria,2HCJX@201174|Actinobacteria	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
MMS3_k127_3991034_7	246197.MXAN_6408	3.787e-36	153.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
MMS3_k127_3991034_0	926566.Terro_1262	8.391e-167	537.0	COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria,2JIIN@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_3991034_5	118163.Ple7327_0607	2.867e-39	157.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,3VJUZ@52604|Pleurocapsales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
MMS3_k127_3991034_1	1267533.KB906735_gene4473	2.288e-140	460.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3991034_2	639030.JHVA01000001_gene2933	1.276e-106	354.0	COG1215@1|root,COG1215@2|Bacteria,3Y7RU@57723|Acidobacteria,2JMZ6@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3991034_4	690850.Desaf_0734	2.223e-87	308.0	COG0438@1|root,COG0438@2|Bacteria,1PERD@1224|Proteobacteria,42VK8@68525|delta/epsilon subdivisions,2WSBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_3991034_3	1123024.AUII01000008_gene1901	6.961e-101	345.0	COG3919@1|root,COG3919@2|Bacteria	2|Bacteria	E	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,CPSase_L_D2,Polysacc_deac_1
MMS3_k127_3991034_8	1049564.TevJSym_ay00040	1.159e-27	118.0	COG0189@1|root,COG0189@2|Bacteria,1MVN2@1224|Proteobacteria,1RS1C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HJ	GNAT family acetyltransferase	cphA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,RimK
MMS3_k127_3991277_0	1267535.KB906767_gene789	6.012e-137	442.0	COG2303@1|root,COG2303@2|Bacteria,3Y6UA@57723|Acidobacteria	57723|Acidobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMS3_k127_3991277_2	234267.Acid_6083	6.936e-20	103.0	COG0683@1|root,COG0683@2|Bacteria,3Y8RR@57723|Acidobacteria	57723|Acidobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMS3_k127_3991277_1	234267.Acid_6083	3.698e-64	229.0	COG0683@1|root,COG0683@2|Bacteria,3Y8RR@57723|Acidobacteria	57723|Acidobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMS3_k127_3997153_0	234267.Acid_3661	4.663e-187	616.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
MMS3_k127_3999071_0	234267.Acid_2158	1.711e-110	370.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,3Y3XN@57723|Acidobacteria	57723|Acidobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
MMS3_k127_3999071_9	1267535.KB906767_gene5183	7.55e-33	134.0	COG0802@1|root,COG0802@2|Bacteria,3Y4WF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0079, ATPase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
MMS3_k127_3999071_11	1499967.BAYZ01000017_gene6214	1.175e-20	101.0	COG3218@1|root,COG3218@2|Bacteria	2|Bacteria	Q	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
MMS3_k127_3999071_3	671143.DAMO_2491	4.407e-90	304.0	COG1028@1|root,COG1028@2|Bacteria,2NQBD@2323|unclassified Bacteria	2|Bacteria	IQ	NAD(P)H binding domain of trans-2-enoyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3999071_5	204669.Acid345_1954	5.147e-80	274.0	COG0177@1|root,COG0177@2|Bacteria,3Y3QD@57723|Acidobacteria,2JI6M@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_3999071_1	330214.NIDE3081	2.61e-102	341.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
MMS3_k127_3999071_8	240015.ACP_1242	3.93e-38	153.0	COG2885@1|root,COG2885@2|Bacteria,3Y425@57723|Acidobacteria,2JHR8@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMS3_k127_3999071_7	234267.Acid_7724	1.176e-53	196.0	COG0127@1|root,COG0127@2|Bacteria,3Y7Z7@57723|Acidobacteria	57723|Acidobacteria	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
MMS3_k127_3999071_4	204669.Acid345_1616	7.681e-87	294.0	COG0689@1|root,COG0689@2|Bacteria,3Y2FP@57723|Acidobacteria,2JHM3@204432|Acidobacteriia	204432|Acidobacteriia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
MMS3_k127_3999071_14	264732.Moth_0516	2.003e-09	66.0	COG5401@1|root,COG5401@2|Bacteria,1V64H@1239|Firmicutes,25JII@186801|Clostridia,42HD7@68295|Thermoanaerobacterales	186801|Clostridia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
MMS3_k127_3999071_12	1123355.JHYO01000018_gene1654	1.323e-15	90.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,36XV8@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
MMS3_k127_3999071_6	935948.KE386493_gene2375	1.31e-66	248.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,248NM@186801|Clostridia,42HXG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3999071_2	234267.Acid_7390	7.177e-100	334.0	COG1028@1|root,COG1028@2|Bacteria,3Y6I4@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
MMS3_k127_3999071_16	639030.JHVA01000001_gene3195	4.035e-06	51.0	COG1501@1|root,COG1501@2|Bacteria,3Y35Y@57723|Acidobacteria,2JI95@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, clan GH-D	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
MMS3_k127_3999071_17	411479.BACUNI_00253	7.782e-05	54.0	COG0860@1|root,COG0860@2|Bacteria,4NEZ9@976|Bacteroidetes,2FMX1@200643|Bacteroidia,4AM77@815|Bacteroidaceae	976|Bacteroidetes	M	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
MMS3_k127_3999071_13	1120965.AUBV01000006_gene2349	2.188e-13	81.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,47MMU@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
MMS3_k127_4015484_1	1267535.KB906767_gene62	4.219e-77	259.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2281,iAF1260.b2281,iAPECO1_1312.APECO1_4284,iB21_1397.B21_02166,iBWG_1329.BWG_2055,iE2348C_1286.E2348C_2421,iEC042_1314.EC042_2522,iEC55989_1330.EC55989_2525,iECABU_c1320.ECABU_c26130,iECBD_1354.ECBD_1380,iECB_1328.ECB_02206,iECDH10B_1368.ECDH10B_2443,iECDH1ME8569_1439.ECDH1ME8569_2218,iECD_1391.ECD_02206,iECED1_1282.ECED1_2745,iECH74115_1262.ECH74115_3420,iECIAI1_1343.ECIAI1_2355,iECIAI39_1322.ECIAI39_2428,iECNA114_1301.ECNA114_2371,iECO103_1326.ECO103_2745,iECO111_1330.ECO111_3029,iECO26_1355.ECO26_3269,iECOK1_1307.ECOK1_2514,iECP_1309.ECP_2320,iECS88_1305.ECS88_2428,iECSE_1348.ECSE_2538,iECSF_1327.ECSF_2158,iECSP_1301.ECSP_3155,iECUMN_1333.ECUMN_2620,iECW_1372.ECW_m2469,iECs_1301.ECs3165,iEKO11_1354.EKO11_1486,iETEC_1333.ETEC_2416,iEcDH1_1363.EcDH1_1376,iEcE24377_1341.EcE24377A_2574,iEcHS_1320.EcHS_A2430,iEcSMS35_1347.EcSMS35_2435,iEcolC_1368.EcolC_1371,iG2583_1286.G2583_2818,iJO1366.b2281,iJR904.b2281,iLF82_1304.LF82_1546,iNRG857_1313.NRG857_11550,iPC815.YPO2548,iSBO_1134.SBO_2314,iSFV_1184.SFV_2348,iSF_1195.SF2357,iSFxv_1172.SFxv_2601,iS_1188.S2492,iSbBS512_1146.SbBS512_E2657,iUMN146_1321.UM146_05410,iUMNK88_1353.UMNK88_2831,iUTI89_1310.UTI89_C2561,iWFL_1372.ECW_m2469,iY75_1357.Y75_RS11960,iZ_1308.Z3540,ic_1306.c2822	Fer4
MMS3_k127_4015484_0	1267533.KB906747_gene18	3.972e-151	482.0	COG1005@1|root,COG1005@2|Bacteria,3Y3VS@57723|Acidobacteria,2JHQZ@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
MMS3_k127_4015484_2	1123368.AUIS01000006_gene660	2.596e-27	114.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,2NBWZ@225057|Acidithiobacillales	225057|Acidithiobacillales	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
MMS3_k127_4018100_2	204669.Acid345_4115	1.762e-69	239.0	COG0334@1|root,COG0334@2|Bacteria,3Y3B4@57723|Acidobacteria,2JI4Q@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
MMS3_k127_4018100_3	204669.Acid345_2759	1.656e-32	132.0	2E5J5@1|root,330AF@2|Bacteria,3Y5HZ@57723|Acidobacteria,2JJVY@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
MMS3_k127_4018100_0	234267.Acid_3577	6.237e-177	572.0	COG0249@1|root,COG0249@2|Bacteria,3Y48T@57723|Acidobacteria	57723|Acidobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
MMS3_k127_4018100_1	28072.Nos7524_4745	8.792e-97	321.0	COG1902@1|root,COG1902@2|Bacteria,1G2EB@1117|Cyanobacteria,1HIRC@1161|Nostocales	1117|Cyanobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
MMS3_k127_4026018_1	204669.Acid345_0553	1.077e-47	176.0	COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia	204432|Acidobacteriia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
MMS3_k127_4026018_0	234267.Acid_1665	1.662e-278	868.0	COG0209@1|root,COG0209@2|Bacteria,3Y3Q1@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
MMS3_k127_4028371_1	1267535.KB906767_gene4971	8.679e-12	77.0	29QWH@1|root,30BWY@2|Bacteria,3Y4SG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4028371_0	204669.Acid345_1153	1.446e-132	449.0	COG0860@1|root,COG0860@2|Bacteria,3Y3M0@57723|Acidobacteria,2JI9V@204432|Acidobacteriia	204432|Acidobacteriia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
MMS3_k127_4064571_0	234267.Acid_4582	6.433e-286	891.0	COG2234@1|root,COG2234@2|Bacteria,3Y435@57723|Acidobacteria	57723|Acidobacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
MMS3_k127_4064571_4	525904.Tter_0838	1.521e-33	138.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria	2|Bacteria	Q	AAA domain	prpA1	-	3.1.3.16,6.5.1.3	ko:K01090,ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
MMS3_k127_4064571_2	1303518.CCALI_00534	1.287e-131	426.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_4064571_3	864702.OsccyDRAFT_1671	4.51e-37	144.0	COG1310@1|root,COG1310@2|Bacteria,1G7SZ@1117|Cyanobacteria,1HBJU@1150|Oscillatoriales	1117|Cyanobacteria	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
MMS3_k127_4064571_5	1267533.KB906734_gene3944	4.862e-33	131.0	COG1977@1|root,COG1977@2|Bacteria,3Y546@57723|Acidobacteria,2JJNC@204432|Acidobacteriia	204432|Acidobacteriia	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS3_k127_4064571_1	266117.Rxyl_0743	1.376e-177	564.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
MMS3_k127_4099788_3	1089544.KB912942_gene5755	1.516e-48	182.0	COG0726@1|root,COG0726@2|Bacteria,2I4TA@201174|Actinobacteria,4EE0Y@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
MMS3_k127_4099788_1	401053.AciPR4_2703	7.295e-67	248.0	2DVRE@1|root,33WVZ@2|Bacteria,3Y60B@57723|Acidobacteria,2JMWX@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4099788_0	1267535.KB906767_gene2478	1.362e-149	487.0	COG0591@1|root,COG0591@2|Bacteria,3Y9FD@57723|Acidobacteria,2JP7P@204432|Acidobacteriia	204432|Acidobacteriia	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
MMS3_k127_4099788_2	1157490.EL26_15620	2.088e-51	198.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4IQ9G@91061|Bacilli,27A01@186823|Alicyclobacillaceae	91061|Bacilli	M	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM
MMS3_k127_4110398_2	234267.Acid_6384	7.721e-37	145.0	COG2020@1|root,COG2020@2|Bacteria,3Y4P4@57723|Acidobacteria	57723|Acidobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMS3_k127_4110398_0	1382359.JIAL01000001_gene2675	1.415e-40	161.0	2DBU8@1|root,2ZB4S@2|Bacteria,3Y31B@57723|Acidobacteria,2JIT7@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
MMS3_k127_4110398_3	1382359.JIAL01000001_gene2676	2.043e-18	87.0	2EA3B@1|root,3348D@2|Bacteria,3Y5J1@57723|Acidobacteria,2JJZE@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4110398_1	234267.Acid_6424	2.358e-38	158.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,3Y3VQ@57723|Acidobacteria	57723|Acidobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
MMS3_k127_4123307_2	1340493.JNIF01000004_gene505	7.658e-64	227.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
MMS3_k127_4123307_0	401053.AciPR4_0954	5.637e-182	583.0	COG0138@1|root,COG0138@2|Bacteria,3Y2QI@57723|Acidobacteria,2JHSU@204432|Acidobacteriia	204432|Acidobacteriia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
MMS3_k127_4123307_3	204669.Acid345_0269	3.504e-29	124.0	2ENGH@1|root,33G40@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4123307_1	309798.COPRO5265_0230	1.068e-101	342.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,42F61@68295|Thermoanaerobacterales	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1,4.3.1.29	ko:K01042,ko:K17468	ko00030,ko00450,ko00970,ko01120,map00030,map00450,map00970,map01120	-	R08219,R10408	RC00544,RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
MMS3_k127_4193039_4	204669.Acid345_2341	3.921e-100	342.0	COG0815@1|root,COG0815@2|Bacteria,3Y4FZ@57723|Acidobacteria,2JKVC@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
MMS3_k127_4193039_3	1267533.KB906738_gene2294	4.869e-146	470.0	COG1186@1|root,COG1186@2|Bacteria,3Y2ZM@57723|Acidobacteria,2JIGW@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMS3_k127_4193039_5	1081640.AGFU01000014_gene2111	2.296e-28	115.0	2E48M@1|root,32Z4G@2|Bacteria,1N6NZ@1224|Proteobacteria,2UH8Q@28211|Alphaproteobacteria,2K7KB@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4193039_2	635013.TherJR_1806	8.423e-163	520.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,2608H@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
MMS3_k127_4193039_1	240015.ACP_2455	2.464e-204	645.0	COG0499@1|root,COG0499@2|Bacteria,3Y2J2@57723|Acidobacteria,2JIFV@204432|Acidobacteriia	204432|Acidobacteriia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMS3_k127_4193039_0	204669.Acid345_3767	8.712e-210	662.0	COG0312@1|root,COG0312@2|Bacteria,3Y6TF@57723|Acidobacteria	57723|Acidobacteria	L	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMS3_k127_4193039_6	204669.Acid345_3766	0.0001282	51.0	COG0312@1|root,COG0312@2|Bacteria,3Y7SM@57723|Acidobacteria	57723|Acidobacteria	L	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
MMS3_k127_4201711_3	1123389.ATXJ01000012_gene2082	4.024e-13	69.0	COG0230@1|root,COG0230@2|Bacteria,1WKP1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
MMS3_k127_4201711_2	935845.JADQ01000032_gene1328	5.839e-28	125.0	COG0664@1|root,COG0664@2|Bacteria,1V5MZ@1239|Firmicutes,4HUY4@91061|Bacilli,26SDY@186822|Paenibacillaceae	91061|Bacilli	K	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_4201711_1	234267.Acid_6078	9.735e-54	208.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PD40,SdrD_B
MMS3_k127_4201711_0	234267.Acid_6079	2.033e-69	244.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_6079|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4231983_0	886293.Sinac_1624	2.22e-113	374.0	COG0546@1|root,COG0546@2|Bacteria,2IYT6@203682|Planctomycetes	203682|Planctomycetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS3_k127_4231983_1	583355.Caka_0526	2.553e-91	314.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23	ko:K01186,ko:K01197,ko:K05988,ko:K11931,ko:K18197	ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,ko04142,map00500,map00511,map00531,map00600,map01100,map02026,map04142	M00076,M00077	R04018,R07824,R07825,R10905,R11309	RC00028,RC00077	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	GH33,GH66,PL11	-	DUF1349,GHL10,Glyco_hydro_20b,Laminin_G_3,NAGidase,fn3
MMS3_k127_4231983_3	1267533.KB906738_gene2437	4.386e-07	55.0	COG3026@1|root,COG3026@2|Bacteria,3Y8M1@57723|Acidobacteria	57723|Acidobacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4231983_2	1267534.KB906754_gene2869	1.667e-40	158.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	VP1287	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	LolA_like
MMS3_k127_4279536_2	404589.Anae109_1654	6.029e-28	115.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,42SN0@68525|delta/epsilon subdivisions,2WPY6@28221|Deltaproteobacteria,2Z0UJ@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
MMS3_k127_4279536_0	1379698.RBG1_1C00001G0493	5.972e-165	538.0	COG1387@1|root,COG1387@2|Bacteria,2NNNK@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase X family	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
MMS3_k127_4279536_1	671143.DAMO_1544	2.321e-44	181.0	COG4191@1|root,COG4191@2|Bacteria,2NPGF@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_451981_1	204669.Acid345_1498	1.2e-74	256.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_451981_3	1254432.SCE1572_25840	0.000359	49.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJ9@29|Myxococcales	28221|Deltaproteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_451981_0	330214.NIDE0029	1.237e-171	548.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
MMS3_k127_48120_5	234267.Acid_6551	4.561e-09	58.0	COG0298@1|root,COG0298@2|Bacteria,3Y5NM@57723|Acidobacteria	57723|Acidobacteria	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
MMS3_k127_48120_1	682795.AciX8_4211	8.727e-180	569.0	COG0409@1|root,COG0409@2|Bacteria,3Y405@57723|Acidobacteria,2JIK0@204432|Acidobacteriia	204432|Acidobacteriia	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
MMS3_k127_48120_2	682795.AciX8_4212	1.799e-152	490.0	COG0309@1|root,COG0309@2|Bacteria,3Y3UH@57723|Acidobacteria,2JK96@204432|Acidobacteriia	204432|Acidobacteriia	O	AIR synthase related protein, C-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
MMS3_k127_48120_4	247490.KSU1_A0079	2.445e-20	95.0	2DCC8@1|root,2ZDND@2|Bacteria	2|Bacteria	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	-	-	-	-	-	-	-	-	-	HypA
MMS3_k127_48120_3	247490.KSU1_A0078	5.507e-35	139.0	COG0680@1|root,COG0680@2|Bacteria,2J190@203682|Planctomycetes	203682|Planctomycetes	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
MMS3_k127_48120_0	247490.KSU1_A0077	3.912e-207	652.0	COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes	203682|Planctomycetes	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
MMS3_k127_485092_1	105559.Nwat_1724	9.611e-29	129.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1WWF7@135613|Chromatiales	135613|Chromatiales	H	TonB-dependent Receptor Plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
MMS3_k127_485092_2	1120963.KB894498_gene2309	3.896e-27	117.0	2CBKC@1|root,32RTJ@2|Bacteria,1N5I0@1224|Proteobacteria,1SACI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_485092_0	324602.Caur_3128	2.673e-152	495.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi,375C1@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
MMS3_k127_52841_1	234267.Acid_2377	4.312e-135	433.0	COG0388@1|root,COG0388@2|Bacteria,3Y7FJ@57723|Acidobacteria	57723|Acidobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
MMS3_k127_52841_0	204669.Acid345_3525	8.775e-221	721.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria,2JHYW@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_52841_5	1343739.PAP_08620	8.222e-16	84.0	COG0500@1|root,arCOG01791@2157|Archaea,2XW4Y@28890|Euryarchaeota	28890|Euryarchaeota	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_52841_7	265072.Mfla_2595	0.0001669	51.0	2EJFZ@1|root,33D6Y@2|Bacteria,1P0SY@1224|Proteobacteria,2W56Y@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_52841_3	32057.KB217478_gene4665	2.818e-36	144.0	COG1716@1|root,COG1716@2|Bacteria,1G7WQ@1117|Cyanobacteria	1117|Cyanobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_52841_4	1267534.KB906754_gene3444	4.519e-36	143.0	COG4319@1|root,COG4319@2|Bacteria,3Y5FP@57723|Acidobacteria,2JN7M@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
MMS3_k127_52841_6	1056816.JAFQ01000004_gene1091	1.215e-09	66.0	COG1280@1|root,COG1280@2|Bacteria,2HRC6@201174|Actinobacteria,4FYBP@85025|Nocardiaceae	201174|Actinobacteria	E	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
MMS3_k127_53450_0	204669.Acid345_1052	1.44e-180	590.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
MMS3_k127_53450_1	1267535.KB906767_gene5290	1.291e-52	194.0	COG0288@1|root,COG0288@2|Bacteria,3Y7V2@57723|Acidobacteria,2JMYT@204432|Acidobacteriia	204432|Acidobacteriia	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
MMS3_k127_53450_2	240015.ACP_1951	1.273e-44	167.0	COG1018@1|root,COG1018@2|Bacteria,3Y4SB@57723|Acidobacteria,2JJAW@204432|Acidobacteriia	204432|Acidobacteriia	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
MMS3_k127_553268_1	1267534.KB906758_gene2092	2.13e-73	261.0	COG0457@1|root,COG0457@2|Bacteria	1267534.KB906758_gene2092|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_553268_3	1231057.AMGD01000041_gene750	1.262e-20	100.0	COG1309@1|root,COG1309@2|Bacteria,1V2VM@1239|Firmicutes,4HFPG@91061|Bacilli,26HEE@186818|Planococcaceae	91061|Bacilli	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
MMS3_k127_553268_0	1340493.JNIF01000003_gene2941	1.17e-92	317.0	COG0820@1|root,COG0820@2|Bacteria,3Y3HQ@57723|Acidobacteria	57723|Acidobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
MMS3_k127_553268_2	204669.Acid345_4103	5.536e-48	179.0	COG1496@1|root,COG1496@2|Bacteria,3Y3J1@57723|Acidobacteria,2JHKU@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
MMS3_k127_554081_0	266117.Rxyl_3008	8.65e-140	455.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria,4CT8G@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM Mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_554081_9	237368.SCABRO_02222	5.831e-16	91.0	2DN50@1|root,32VJ4@2|Bacteria,2J04A@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
MMS3_k127_554081_1	1382359.JIAL01000001_gene1267	4.987e-109	368.0	COG3225@1|root,COG3225@2|Bacteria,3Y6WR@57723|Acidobacteria	57723|Acidobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
MMS3_k127_554081_5	234267.Acid_4516	5.467e-68	240.0	COG1277@1|root,COG1277@2|Bacteria,3Y6D0@57723|Acidobacteria	57723|Acidobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_554081_2	234267.Acid_4515	6.801e-108	359.0	COG1131@1|root,COG1131@2|Bacteria,3Y6FZ@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_554081_4	266117.Rxyl_3007	1.478e-77	267.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4CT7G@84995|Rubrobacteria	84995|Rubrobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_554081_3	1267535.KB906767_gene2661	6.039e-80	273.0	COG1573@1|root,COG1573@2|Bacteria,3Y4AT@57723|Acidobacteria,2JJ4U@204432|Acidobacteriia	204432|Acidobacteriia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_554081_6	324602.Caur_3390	6.196e-46	169.0	COG2947@1|root,COG2947@2|Bacteria,2G93S@200795|Chloroflexi,375T3@32061|Chloroflexia	32061|Chloroflexia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
MMS3_k127_554081_8	999541.bgla_2g02470	2.701e-27	114.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,1K48E@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
MMS3_k127_554081_7	682795.AciX8_2751	4.253e-30	132.0	COG1322@1|root,COG1322@2|Bacteria,3Y3JC@57723|Acidobacteria,2JHYC@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_554081_10	525897.Dbac_0347	3.134e-08	60.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,42V1I@68525|delta/epsilon subdivisions,2WRH0@28221|Deltaproteobacteria,2MD3V@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
MMS3_k127_560572_3	316067.Geob_3538	2.308e-106	352.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
MMS3_k127_560572_10	1267535.KB906767_gene4057	1.095e-56	217.0	COG1807@1|root,COG1807@2|Bacteria,3Y3BJ@57723|Acidobacteria,2JI9B@204432|Acidobacteriia	204432|Acidobacteriia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_560572_8	370438.PTH_1800	6.768e-63	228.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,260JZ@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
MMS3_k127_560572_6	1121920.AUAU01000022_gene2498	1.138e-74	258.0	COG2518@1|root,COG2518@2|Bacteria,3Y5EB@57723|Acidobacteria	57723|Acidobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	PCMT
MMS3_k127_560572_12	1156937.MFUM_1010089	3.161e-49	184.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
MMS3_k127_560572_1	1267535.KB906767_gene890	2.93e-134	442.0	COG0531@1|root,COG0531@2|Bacteria,3Y7AX@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMS3_k127_560572_4	204669.Acid345_2619	3.595e-93	329.0	COG3975@1|root,COG3975@2|Bacteria,3Y411@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
MMS3_k127_560572_15	278963.ATWD01000001_gene3709	1.224e-42	165.0	COG0204@1|root,COG0204@2|Bacteria,3Y49D@57723|Acidobacteria,2JJ6K@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS3_k127_560572_2	682795.AciX8_2419	1.079e-126	413.0	COG1044@1|root,COG1044@2|Bacteria,3Y2JC@57723|Acidobacteria,2JI2Y@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
MMS3_k127_560572_5	1382359.JIAL01000001_gene2444	1.185e-75	263.0	COG0101@1|root,COG0101@2|Bacteria,3Y2MS@57723|Acidobacteria,2JIWS@204432|Acidobacteriia	204432|Acidobacteriia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
MMS3_k127_560572_14	1267535.KB906767_gene3397	4.001e-43	159.0	COG1977@1|root,COG1977@2|Bacteria,3Y5J3@57723|Acidobacteria,2JJVU@204432|Acidobacteriia	204432|Acidobacteriia	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_560572_17	933262.AXAM01000172_gene934	3.405e-25	108.0	COG2337@1|root,COG2337@2|Bacteria,1N1DE@1224|Proteobacteria,42WAI@68525|delta/epsilon subdivisions,2WRAJ@28221|Deltaproteobacteria,2MNJZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
MMS3_k127_560572_0	1382359.JIAL01000001_gene657	3.1e-225	702.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
MMS3_k127_560572_11	1510531.JQJJ01000008_gene4101	1.297e-51	186.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2U735@28211|Alphaproteobacteria,3JY2H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YCII-related domain	MA20_04055	-	-	-	-	-	-	-	-	-	-	-	YCII
MMS3_k127_560572_13	316055.RPE_4736	5.215e-49	178.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2U5A4@28211|Alphaproteobacteria,3JZY1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	MA20_04095	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
MMS3_k127_560572_9	1267535.KB906767_gene4248	3.003e-57	209.0	COG2318@1|root,COG2318@2|Bacteria,3Y82J@57723|Acidobacteria,2JN4W@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_560572_7	1382359.JIAL01000001_gene658	7.597e-64	223.0	COG1733@1|root,COG1733@2|Bacteria,3Y7XV@57723|Acidobacteria,2JN1Y@204432|Acidobacteriia	204432|Acidobacteriia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
MMS3_k127_560572_16	1267535.KB906767_gene5119	4.416e-41	156.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria,2JI4V@204432|Acidobacteriia	204432|Acidobacteriia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
MMS3_k127_564498_0	1382359.JIAL01000001_gene611	1.397e-95	329.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria,2JM5G@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_564498_1	1267535.KB906767_gene4100	4.648e-82	283.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
MMS3_k127_564498_2	1123277.KB893243_gene138	1.355e-41	158.0	COG1082@1|root,COG1082@2|Bacteria,4NFKF@976|Bacteroidetes,47P9Y@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
MMS3_k127_565912_2	929703.KE386491_gene3506	2.562e-33	141.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,47N0C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
MMS3_k127_565912_1	1089550.ATTH01000001_gene1359	3.868e-37	155.0	COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,1FK2Q@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
MMS3_k127_565912_3	1121104.AQXH01000001_gene1377	2.315e-31	138.0	2CIUH@1|root,32S8I@2|Bacteria,4NWAC@976|Bacteroidetes,1IYW7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_565912_0	204669.Acid345_0115	8.386e-158	513.0	COG1052@1|root,COG1052@2|Bacteria,3Y2MD@57723|Acidobacteria,2JHYI@204432|Acidobacteriia	204432|Acidobacteriia	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
MMS3_k127_567588_0	278963.ATWD01000003_gene12	0.0	1056.0	COG1554@1|root,COG1554@2|Bacteria,3Y8FW@57723|Acidobacteria,2JNF8@204432|Acidobacteriia	204432|Acidobacteriia	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_567588_4	552811.Dehly_0392	1.02e-51	192.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
MMS3_k127_567588_5	665029.EAMY_3190	2.547e-06	58.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,3X5M2@551|Erwinia	1236|Gammaproteobacteria	E	asparagine synthetase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
MMS3_k127_567588_2	682795.AciX8_1464	2.63e-222	697.0	COG0364@1|root,COG0364@2|Bacteria,3Y627@57723|Acidobacteria,2JKTN@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
MMS3_k127_567588_6	204669.Acid345_3709	1.094e-05	49.0	COG1023@1|root,COG1023@2|Bacteria,3Y2ZP@57723|Acidobacteria,2JJT6@204432|Acidobacteriia	204432|Acidobacteriia	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
MMS3_k127_567588_1	1038860.AXAP01000029_gene683	1.506e-296	919.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,3JWSI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Phosphoglucose isomerase	pgi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
MMS3_k127_567588_3	278963.ATWD01000001_gene1097	8.986e-55	194.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,3Y7AG@57723|Acidobacteria,2JKC5@204432|Acidobacteriia	204432|Acidobacteriia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_32,rve,rve_3
MMS3_k127_571761_3	1340493.JNIF01000004_gene57	5.162e-29	126.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria	57723|Acidobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
MMS3_k127_571761_2	945713.IALB_1744	6.758e-50	182.0	COG0691@1|root,COG0691@2|Bacteria	2|Bacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
MMS3_k127_571761_1	234267.Acid_0699	3.254e-57	215.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMS3_k127_571761_0	247490.KSU1_B0467	1.031e-128	419.0	COG0500@1|root,COG2226@2|Bacteria,2IYB6@203682|Planctomycetes	203682|Planctomycetes	Q	Methylase involved in ubiquinone menaquinone	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
MMS3_k127_574538_2	1125863.JAFN01000001_gene2493	8.506e-56	200.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	denitrification pathway	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
MMS3_k127_574538_0	234267.Acid_0432	4.746e-172	554.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
MMS3_k127_574538_1	756067.MicvaDRAFT_4707	6.396e-92	309.0	COG0282@1|root,COG0282@2|Bacteria,1G214@1117|Cyanobacteria,1H897@1150|Oscillatoriales	1117|Cyanobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
MMS3_k127_575559_1	401053.AciPR4_2842	8.32e-251	791.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria,2JIGT@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_575559_0	1267533.KB906735_gene4765	2.737e-312	976.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Trehalase
MMS3_k127_575559_2	1122604.JONR01000040_gene4058	8.43e-66	241.0	COG3115@1|root,COG3115@2|Bacteria,1QR19@1224|Proteobacteria,1S736@1236|Gammaproteobacteria,1X6RG@135614|Xanthomonadales	135614|Xanthomonadales	D	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
MMS3_k127_57934_2	1267535.KB906767_gene3933	4.777e-119	391.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria,2JI4A@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_57934_1	1292034.OR37_02327	8.705e-146	482.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2TTHT@28211|Alphaproteobacteria,2KHUT@204458|Caulobacterales	204458|Caulobacterales	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
MMS3_k127_57934_0	1267535.KB906767_gene4724	8.573e-206	670.0	COG0577@1|root,COG0577@2|Bacteria	1267535.KB906767_gene4724|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_57934_4	234267.Acid_4795	5.087e-31	124.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_57934_3	1267533.KB906734_gene4365	3.471e-49	177.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_581992_0	525904.Tter_2038	7.87e-195	619.0	COG2407@1|root,COG2407@2|Bacteria,2NR9P@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the conversion of L-arabinose to L-ribulose	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
MMS3_k127_581992_1	1267535.KB906767_gene1717	6.8e-79	274.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y8N8@57723|Acidobacteria,2JNIX@204432|Acidobacteriia	1267535.KB906767_gene1717|-	EG	L-rhamnose-proton symport protein (RhaT)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_586133_3	1340493.JNIF01000003_gene3658	1.861e-30	135.0	COG1240@1|root,COG1240@2|Bacteria,3Y474@57723|Acidobacteria	57723|Acidobacteria	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
MMS3_k127_586133_2	204669.Acid345_4310	1.434e-63	229.0	COG1082@1|root,COG1082@2|Bacteria,3Y2PT@57723|Acidobacteria,2JI9Z@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_586133_0	204669.Acid345_2288	1.523e-116	387.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria,2JI77@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
MMS3_k127_586133_1	886293.Sinac_1892	7.703e-71	260.0	COG0407@1|root,COG0407@2|Bacteria,2IXZG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,URO-D
MMS3_k127_587296_6	441620.Mpop_3217	7.637e-17	82.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,1JR0D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_587296_2	682795.AciX8_3594	4.148e-116	407.0	COG1629@1|root,COG4771@2|Bacteria,3Y461@57723|Acidobacteria,2JHPM@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_587296_1	234267.Acid_0085	1.998e-119	407.0	COG1132@1|root,COG1132@2|Bacteria,3Y6PT@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
MMS3_k127_587296_4	13690.CP98_04528	5.885e-34	140.0	COG0500@1|root,COG0726@1|root,COG1215@1|root,COG0500@2|Bacteria,COG0726@2|Bacteria,COG1215@2|Bacteria,1RIMV@1224|Proteobacteria,2TW81@28211|Alphaproteobacteria,2KECZ@204457|Sphingomonadales	204457|Sphingomonadales	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	NodS
MMS3_k127_587296_3	886293.Sinac_4404	8.751e-63	231.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_587296_8	926564.KI911764_gene4523	1.83e-08	68.0	2BB39@1|root,324JH@2|Bacteria,2H9FU@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_587296_0	335543.Sfum_3546	2.54e-294	929.0	COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,1R42U@1224|Proteobacteria,42UMM@68525|delta/epsilon subdivisions,2WQVW@28221|Deltaproteobacteria,2MS0N@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
MMS3_k127_587296_5	397278.JOJN01000007_gene3225	2.212e-17	90.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4DNS9@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
MMS3_k127_587296_7	247490.KSU1_C0080	1.202e-13	77.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1822,HEAT_2
MMS3_k127_587296_9	316274.Haur_3379	1.773e-05	54.0	COG1672@1|root,COG1672@2|Bacteria,2GAG9@200795|Chloroflexi,3760S@32061|Chloroflexia	32061|Chloroflexia	S	AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
MMS3_k127_588516_2	1121920.AUAU01000012_gene2703	3.698e-31	123.0	COG2102@1|root,COG2102@2|Bacteria,3Y46Z@57723|Acidobacteria	57723|Acidobacteria	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
MMS3_k127_588516_1	1333998.M2A_1971	4.971e-59	217.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,2U7IG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
MMS3_k127_588516_0	404589.Anae109_1211	3.195e-75	265.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
MMS3_k127_589824_0	1267535.KB906767_gene2004	5.37e-88	298.0	COG3391@1|root,COG3391@2|Bacteria,3Y4CD@57723|Acidobacteria,2JJ1Y@204432|Acidobacteriia	204432|Acidobacteriia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_589824_3	335543.Sfum_3315	3.344e-35	152.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42W4B@68525|delta/epsilon subdivisions,2WP0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMS3_k127_589824_1	204669.Acid345_0180	1.844e-73	254.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
MMS3_k127_589824_2	234267.Acid_5351	6.005e-40	153.0	COG0682@1|root,COG0682@2|Bacteria,3Y4HT@57723|Acidobacteria	57723|Acidobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
MMS3_k127_596216_9	1267535.KB906767_gene3009	4.342e-07	53.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	CBM9_1,NPCBM_assoc,PIG-L
MMS3_k127_596216_8	1530186.JQEY01000024_gene2454	3.515e-11	69.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	dctD	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_596216_6	1267535.KB906767_gene3226	1.72e-27	121.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_596216_1	1279009.ADICEAN_01483	8.614e-95	331.0	COG0668@1|root,COG0668@2|Bacteria,4NFC6@976|Bacteroidetes,47YNQ@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	mscM	-	-	-	-	-	-	-	-	-	-	-	MS_channel
MMS3_k127_596216_0	234267.Acid_5476	9.343e-129	416.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,3Y2H3@57723|Acidobacteria	57723|Acidobacteria	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003,cNMP_binding
MMS3_k127_596216_7	593750.Metfor_1237	7.562e-13	72.0	COG3350@1|root,arCOG04507@2157|Archaea	2157|Archaea	P	PFAM YHS domain	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
MMS3_k127_596216_3	670487.Ocepr_0593	6.655e-66	237.0	COG2041@1|root,COG2041@2|Bacteria,1WI25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
MMS3_k127_596216_5	316067.Geob_2070	3.556e-36	146.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,42VMX@68525|delta/epsilon subdivisions,2WS5W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
MMS3_k127_596216_2	926690.KE386573_gene613	6.629e-68	243.0	COG3173@1|root,arCOG04682@2157|Archaea,2Y2X5@28890|Euryarchaeota,23ZFE@183963|Halobacteria	183963|Halobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_596216_4	1262915.BN574_00279	1.261e-40	153.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4H2GC@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMS3_k127_597390_2	227377.CBU_1788	4.342e-51	188.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
MMS3_k127_597390_3	1173028.ANKO01000009_gene1725	1.206e-33	130.0	COG1598@1|root,COG1598@2|Bacteria,1G8ZQ@1117|Cyanobacteria,1HD3T@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
MMS3_k127_597390_5	118173.KB235914_gene2326	1.038e-18	88.0	COG1724@1|root,COG1724@2|Bacteria,1G890@1117|Cyanobacteria,1HC6J@1150|Oscillatoriales	1117|Cyanobacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
MMS3_k127_597390_7	1123276.KB893248_gene17	8.122e-12	72.0	COG4319@1|root,COG4319@2|Bacteria,4NSA0@976|Bacteroidetes,47RMW@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
MMS3_k127_597390_1	1123252.ATZF01000006_gene706	1.255e-112	375.0	COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,4HDPM@91061|Bacilli,27D7W@186824|Thermoactinomycetaceae	91061|Bacilli	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
MMS3_k127_597390_4	1095769.CAHF01000015_gene2795	8.168e-29	123.0	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,2VSBK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
MMS3_k127_597390_0	1121904.ARBP01000013_gene390	1.496e-160	519.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,47JG2@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase C-terminal domain	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
MMS3_k127_597390_6	502025.Hoch_5099	3.19e-12	66.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_59921_0	671143.DAMO_1669	2.818e-73	271.0	COG0845@1|root,COG2010@1|root,COG0845@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,FIVAR,HlyD_3,PA14,RNA_pol_Rpb1_5
MMS3_k127_59921_1	83406.HDN1F_07940	6.042e-09	64.0	COG2010@1|root,COG2010@2|Bacteria,1N63J@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome c	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
MMS3_k127_600108_2	1267533.KB906736_gene1013	3.819e-112	366.0	COG2936@1|root,COG2936@2|Bacteria,3Y33N@57723|Acidobacteria	57723|Acidobacteria	S	Hydrolase CocE NonD family	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_600108_0	1267535.KB906767_gene4530	8.292e-160	514.0	COG3875@1|root,COG3875@2|Bacteria,3Y6SH@57723|Acidobacteria,2JKUN@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
MMS3_k127_600108_11	655815.ZPR_3498	1.327e-05	53.0	COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1I51S@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
MMS3_k127_600108_1	234267.Acid_7201	4.134e-151	489.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_600108_4	1267533.KB906735_gene4737	1.26e-38	153.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_600108_3	204669.Acid345_4326	2.719e-77	266.0	COG1235@1|root,COG1235@2|Bacteria,3Y3DW@57723|Acidobacteria,2JI3X@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMS3_k127_600108_5	715226.ABI_05250	3.385e-24	104.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria	1224|Proteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
MMS3_k127_600108_8	644282.Deba_2541	2.278e-08	55.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42U5G@68525|delta/epsilon subdivisions,2WQ28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
MMS3_k127_600108_7	1125863.JAFN01000001_gene307	5.285e-11	63.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
MMS3_k127_601004_1	479434.Sthe_0997	7.099e-48	173.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,27XUB@189775|Thermomicrobia	189775|Thermomicrobia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_601004_3	525904.Tter_0786	6.379e-36	139.0	COG2142@1|root,COG2142@2|Bacteria	2|Bacteria	C	succinate dehydrogenase activity	sdhD	-	-	ko:K00242,ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMS3_k127_601004_2	867903.ThesuDRAFT_00391	1.413e-37	145.0	COG2009@1|root,COG2009@2|Bacteria,1VKGI@1239|Firmicutes,24VB1@186801|Clostridia	186801|Clostridia	C	TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMS3_k127_601004_4	1267535.KB906767_gene4385	2.717e-32	131.0	2CK96@1|root,3346F@2|Bacteria,3Y5N2@57723|Acidobacteria,2JJZD@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_601004_0	204669.Acid345_3624	3.019e-132	429.0	COG1633@1|root,COG1633@2|Bacteria,3Y42J@57723|Acidobacteria,2JM0I@204432|Acidobacteriia	204432|Acidobacteriia	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMS3_k127_60570_4	1267535.KB906767_gene1282	7.841e-15	75.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
MMS3_k127_60570_5	1267535.KB906767_gene1282	3.46e-09	61.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
MMS3_k127_60570_2	338966.Ppro_1689	1.111e-57	206.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria,43V0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
MMS3_k127_60570_3	281090.Lxx14470	9.053e-26	116.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4FKTB@85023|Microbacteriaceae	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
MMS3_k127_60570_1	204669.Acid345_1194	1.021e-121	398.0	COG0752@1|root,COG0752@2|Bacteria,3Y3QC@57723|Acidobacteria,2JI3H@204432|Acidobacteriia	204432|Acidobacteriia	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
MMS3_k127_60570_0	240015.ACP_0591	7.807e-165	543.0	COG0751@1|root,COG0751@2|Bacteria,3Y3KN@57723|Acidobacteria,2JIJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
MMS3_k127_60570_6	639282.DEFDS_0235	2.443e-05	47.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GF76@200930|Deferribacteres	200930|Deferribacteres	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS3_k127_621292_13	671143.DAMO_1381	5.154e-10	62.0	COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	ko:K19591,ko:K22491	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR_1
MMS3_k127_621292_5	326427.Cagg_3314	2.064e-45	166.0	COG3254@1|root,COG3254@2|Bacteria,2G9IM@200795|Chloroflexi,3778J@32061|Chloroflexia	32061|Chloroflexia	S	Pfam:DUF718	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
MMS3_k127_621292_7	1382359.JIAL01000001_gene2677	1.881e-35	147.0	2C730@1|root,31C19@2|Bacteria,3Y52Y@57723|Acidobacteria,2JJFD@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_621292_0	204669.Acid345_2146	3.175e-119	411.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
MMS3_k127_621292_4	234267.Acid_1849	2.802e-62	225.0	COG1028@1|root,COG1028@2|Bacteria,3Y6JP@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_621292_12	194439.CT0237	8.752e-11	65.0	COG0695@1|root,COG0695@2|Bacteria,1FEC4@1090|Chlorobi	1090|Chlorobi	O	glutaredoxin 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
MMS3_k127_621292_3	639030.JHVA01000001_gene3951	5.147e-80	274.0	COG2120@1|root,COG2120@2|Bacteria,3Y3NP@57723|Acidobacteria,2JIEH@204432|Acidobacteriia	204432|Acidobacteriia	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
MMS3_k127_621292_2	204669.Acid345_1959	4.263e-82	277.0	COG0586@1|root,COG0586@2|Bacteria,3Y364@57723|Acidobacteria,2JI2N@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_621292_1	639030.JHVA01000001_gene635	2.581e-86	298.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria,2JI98@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
MMS3_k127_621292_8	1382359.JIAL01000001_gene2770	3.485e-21	97.0	COG2952@1|root,COG2952@2|Bacteria,3Y55F@57723|Acidobacteria,2JJNJ@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF507)	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
MMS3_k127_621292_10	926566.Terro_1879	4.171e-13	72.0	COG2952@1|root,COG2952@2|Bacteria,3Y57Q@57723|Acidobacteria,2JJRA@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF507)	-	-	-	-	-	-	-	-	-	-	-	-	DUF507
MMS3_k127_621292_14	1347086.CCBA010000024_gene3046	1.476e-05	48.0	2EJ6D@1|root,33CXK@2|Bacteria,1UB1Y@1239|Firmicutes,4IMEV@91061|Bacilli,1ZJZP@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_621292_9	243231.GSU1153	8.887e-14	79.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,42N70@68525|delta/epsilon subdivisions,2WR7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Polypeptide-transport-associated domain protein ShlB-type	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
MMS3_k127_647725_5	861299.J421_4362	4.918e-11	65.0	COG0589@1|root,COG0589@2|Bacteria,1ZTUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_647725_0	1210884.HG799462_gene8047	3.606e-202	640.0	COG1914@1|root,COG1914@2|Bacteria,2J0SG@203682|Planctomycetes	203682|Planctomycetes	P	Natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
MMS3_k127_647725_4	1340493.JNIF01000003_gene4320	4.753e-66	233.0	COG1321@1|root,COG1321@2|Bacteria,3Y5SN@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
MMS3_k127_647725_3	234267.Acid_5208	7.727e-94	317.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,3Y3HP@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM glutamate formiminotransferase	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
MMS3_k127_647725_2	1144275.COCOR_03556	1.007e-132	444.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,42PUK@68525|delta/epsilon subdivisions,2WIN4@28221|Deltaproteobacteria,2YU7Y@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
MMS3_k127_647725_1	945713.IALB_1068	3.349e-136	453.0	COG1022@1|root,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
MMS3_k127_648956_0	204669.Acid345_1412	2.932e-71	250.0	COG2316@1|root,COG2316@2|Bacteria,3Y4GI@57723|Acidobacteria,2JJBG@204432|Acidobacteriia	204432|Acidobacteriia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMS3_k127_648956_1	105422.BBPM01000003_gene5720	1.253e-32	140.0	COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria,2NEPG@228398|Streptacidiphilus	201174|Actinobacteria	S	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
MMS3_k127_648956_2	1144275.COCOR_01387	1.516e-25	108.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2YWUY@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
MMS3_k127_650811_0	177437.HRM2_08750	1.207e-124	417.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2MPTW@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_650811_1	1499967.BAYZ01000095_gene4278	6.678e-84	291.0	COG0812@1|root,COG0812@2|Bacteria	2|Bacteria	M	UDP-N-acetylmuramate dehydrogenase activity	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
MMS3_k127_659426_4	1382306.JNIM01000001_gene2361	1.102e-49	182.0	COG1472@1|root,COG1472@2|Bacteria,2G639@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
MMS3_k127_659426_2	386456.JQKN01000007_gene3251	2.857e-121	404.0	arCOG02685@1|root,arCOG02685@2157|Archaea,2XV10@28890|Euryarchaeota	28890|Euryarchaeota	G	COG0477 Permeases of the major facilitator superfamily	csbC	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
MMS3_k127_659426_6	426355.Mrad2831_2926	7.119e-21	98.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,1JSNS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve_3
MMS3_k127_659426_5	1112216.JH594426_gene3678	9.871e-27	120.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2K4Q4@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
MMS3_k127_659426_1	234267.Acid_5703	5.374e-122	410.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_5703|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_659426_3	224325.AF_0676	1.88e-55	204.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMS3_k127_659426_0	234267.Acid_7175	1.169e-131	428.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria	57723|Acidobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
MMS3_k127_659426_7	443598.AUFA01000009_gene5715	2.688e-14	74.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2UDW5@28211|Alphaproteobacteria,3K4D3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
MMS3_k127_659426_9	288000.BBta_1538	1.501e-08	58.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2UDW5@28211|Alphaproteobacteria,3K4D3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
MMS3_k127_659426_8	690850.Desaf_3258	6.419e-14	75.0	COG3293@1|root,COG3293@2|Bacteria,1R5NV@1224|Proteobacteria,430FR@68525|delta/epsilon subdivisions,2WVKI@28221|Deltaproteobacteria,2MFEK@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
MMS3_k127_660042_8	1267535.KB906767_gene5117	3.963e-61	220.0	COG1253@1|root,COG1253@2|Bacteria,3Y3MC@57723|Acidobacteria,2JIF9@204432|Acidobacteriia	204432|Acidobacteriia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
MMS3_k127_660042_7	204669.Acid345_3535	7.258e-93	314.0	COG1159@1|root,COG1159@2|Bacteria,3Y2GE@57723|Acidobacteria,2JIIA@204432|Acidobacteriia	204432|Acidobacteriia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
MMS3_k127_660042_10	716928.AJQT01000032_gene2707	1.842e-25	120.0	COG3568@1|root,COG3842@1|root,COG3568@2|Bacteria,COG3842@2|Bacteria,1P2WU@1224|Proteobacteria,2U2FR@28211|Alphaproteobacteria,4BCKJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
MMS3_k127_660042_1	204669.Acid345_1394	9.272e-184	587.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria,2JIIE@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_660042_3	204669.Acid345_1393	3.915e-154	513.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria,2JIN2@204432|Acidobacteriia	204432|Acidobacteriia	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
MMS3_k127_660042_9	247490.KSU1_C0054	1.057e-56	207.0	COG2231@1|root,COG2231@2|Bacteria,2IZ9A@203682|Planctomycetes	203682|Planctomycetes	L	endonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
MMS3_k127_660042_0	1121920.AUAU01000016_gene1339	1.046e-216	687.0	COG2804@1|root,COG2804@2|Bacteria,3Y2IS@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
MMS3_k127_660042_2	204669.Acid345_1391	2.994e-171	544.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMS3_k127_660042_4	204669.Acid345_1390	1.55e-151	488.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	2|Bacteria	NU	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
MMS3_k127_660042_6	204669.Acid345_1389	3.258e-120	407.0	COG3852@1|root,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8
MMS3_k127_660042_5	204669.Acid345_1388	2.383e-127	418.0	COG2204@1|root,COG2204@2|Bacteria,3Y3T2@57723|Acidobacteria,2JIG9@204432|Acidobacteriia	57723|Acidobacteria	T	response regulator, receiver	-	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_673079_2	234267.Acid_5940	1.052e-56	204.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMS3_k127_673079_0	1267533.KB906737_gene1499	3.452e-281	879.0	COG3345@1|root,COG3345@2|Bacteria,3Y6JU@57723|Acidobacteria,2JKCG@204432|Acidobacteriia	204432|Acidobacteriia	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
MMS3_k127_673079_3	1267535.KB906767_gene1609	1.115e-55	207.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
MMS3_k127_673079_1	65393.PCC7424_3523	1.227e-121	418.0	COG2199@1|root,COG3829@1|root,COG4191@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1FZWU@1117|Cyanobacteria,3KHMA@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
MMS3_k127_676267_2	330214.NIDE3895	5.962e-33	134.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	ymaD	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
MMS3_k127_676267_3	497964.CfE428DRAFT_5140	4.307e-22	98.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,46SCB@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Conserved region in glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
MMS3_k127_676267_0	1267535.KB906767_gene5312	8.85e-105	351.0	COG0391@1|root,COG0391@2|Bacteria,3Y3ZE@57723|Acidobacteria,2JITK@204432|Acidobacteriia	204432|Acidobacteriia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
MMS3_k127_676267_4	1382359.JIAL01000001_gene1384	7.944e-22	104.0	COG0457@1|root,COG0457@2|Bacteria,3Y4XQ@57723|Acidobacteria,2JJFK@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMS3_k127_676267_1	234267.Acid_5201	3.338e-44	168.0	COG1477@1|root,COG1477@2|Bacteria,3Y4B0@57723|Acidobacteria	57723|Acidobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMS3_k127_67923_3	234267.Acid_0027	3.518e-82	278.0	COG1082@1|root,COG1082@2|Bacteria,3Y6EB@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
MMS3_k127_67923_1	1267535.KB906767_gene3466	1.156e-92	312.0	COG1122@1|root,COG1122@2|Bacteria,3Y84B@57723|Acidobacteria	57723|Acidobacteria	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
MMS3_k127_67923_4	1267535.KB906767_gene3465	2.004e-81	279.0	COG0310@1|root,COG0619@1|root,COG0310@2|Bacteria,COG0619@2|Bacteria,3Y8I6@57723|Acidobacteria	57723|Acidobacteria	P	Cobalt uptake substrate-specific transmembrane region	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
MMS3_k127_67923_0	1122963.AUHB01000016_gene4361	5.023e-134	437.0	COG0310@1|root,COG0310@2|Bacteria,1NTQK@1224|Proteobacteria,2U0RQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
MMS3_k127_67923_2	1089550.ATTH01000001_gene978	6.547e-87	297.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1FIR3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GK	ROK family	nagC	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
MMS3_k127_67923_5	204669.Acid345_0630	4.963e-77	272.0	COG1721@1|root,COG1721@2|Bacteria,3Y5V9@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMS3_k127_680249_1	204669.Acid345_4765	4.882e-218	685.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria,2JIAE@204432|Acidobacteriia	204432|Acidobacteriia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS3_k127_680249_5	671143.DAMO_2768	3.885e-44	165.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_680249_4	671143.DAMO_2768	7.397e-47	173.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_680249_11	931627.MycrhDRAFT_4159	7.718e-10	63.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,238SJ@1762|Mycobacteriaceae	201174|Actinobacteria	O	Peroxiredoxin	ahpE	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
MMS3_k127_680249_9	266117.Rxyl_1128	7.466e-15	78.0	COG1225@1|root,COG1225@2|Bacteria,2HG0X@201174|Actinobacteria,4CTWJ@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS3_k127_680249_12	73044.JNXP01000003_gene4118	1.481e-09	60.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria	201174|Actinobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpE	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
MMS3_k127_680249_10	82654.Pse7367_0154	4.643e-12	70.0	COG1225@1|root,COG1225@2|Bacteria,1G6V9@1117|Cyanobacteria	1117|Cyanobacteria	O	AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMS3_k127_680249_2	1267533.KB906733_gene3362	6.365e-156	513.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
MMS3_k127_680249_0	671143.DAMO_1249	3.248e-251	804.0	COG1615@1|root,COG1615@2|Bacteria,2NQSF@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
MMS3_k127_680249_6	1267535.KB906767_gene430	2.492e-43	161.0	COG3682@1|root,COG3682@2|Bacteria,3Y8B7@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
MMS3_k127_680249_3	234267.Acid_1032	3.512e-54	210.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,Peptidase_M56,TonB_C
MMS3_k127_680249_7	204669.Acid345_0799	2.144e-32	143.0	COG0607@1|root,COG1651@1|root,COG3266@1|root,COG4243@1|root,COG0607@2|Bacteria,COG1651@2|Bacteria,COG3266@2|Bacteria,COG4243@2|Bacteria,3Y5CK@57723|Acidobacteria,2JJU9@204432|Acidobacteriia	204432|Acidobacteriia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
MMS3_k127_682776_15	471875.RUMLAC_00756	1.465e-07	53.0	2DPDN@1|root,331NP@2|Bacteria,1VFF8@1239|Firmicutes,24S9D@186801|Clostridia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_682776_6	1267533.KB906736_gene1104	1.431e-68	246.0	COG0673@1|root,COG0673@2|Bacteria,3Y32B@57723|Acidobacteria,2JIB3@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_682776_7	204669.Acid345_0096	9.187e-68	238.0	COG0730@1|root,COG0730@2|Bacteria,3Y52Z@57723|Acidobacteria,2JJKT@204432|Acidobacteriia	204432|Acidobacteriia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_682776_13	1267535.KB906767_gene2307	3.686e-14	85.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	asmA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475	-	ko:K07289,ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA,AsmA_2
MMS3_k127_682776_11	1123371.ATXH01000014_gene1580	4.545e-34	139.0	COG0500@1|root,COG0778@1|root,COG0778@2|Bacteria,COG2226@2|Bacteria,2GIDX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_682776_2	204669.Acid345_0708	7.269e-98	322.0	COG1100@1|root,COG1100@2|Bacteria,3Y7CQ@57723|Acidobacteria	57723|Acidobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
MMS3_k127_682776_5	1125863.JAFN01000001_gene724	3.952e-70	244.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_682776_9	269799.Gmet_3382	5.345e-54	208.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1QTV1@1224|Proteobacteria,43BSP@68525|delta/epsilon subdivisions,2X7EK@28221|Deltaproteobacteria,43W43@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_682776_0	240015.ACP_1858	1.858e-167	541.0	COG1032@1|root,COG1032@2|Bacteria,3Y2NI@57723|Acidobacteria,2JIYK@204432|Acidobacteriia	204432|Acidobacteriia	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
MMS3_k127_682776_1	204669.Acid345_3623	7.754e-121	400.0	COG1055@1|root,COG1055@2|Bacteria,3Y5VM@57723|Acidobacteria,2JP3Z@204432|Acidobacteriia	204432|Acidobacteriia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	ArsB
MMS3_k127_682776_14	929712.KI912613_gene4279	1.615e-10	65.0	2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_682776_3	485913.Krac_12208	9.226e-76	257.0	COG0225@1|root,COG0225@2|Bacteria	2|Bacteria	O	peptide-methionine (S)-S-oxide reductase activity	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
MMS3_k127_682776_12	1158146.KB907121_gene1044	8.232e-27	111.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1WZ1M@135613|Chromatiales	135613|Chromatiales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
MMS3_k127_682776_4	1210884.HG799462_gene7991	6.264e-74	258.0	COG1351@1|root,COG1351@2|Bacteria,2J0W9@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	-	-	-	-	-	-	-	-	-	-	Thy1
MMS3_k127_682776_10	1206732.BAGD01000278_gene6376	2.734e-39	154.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,DUF4396
MMS3_k127_682776_8	656024.FsymDg_2257	4.379e-62	224.0	COG2132@1|root,COG2132@2|Bacteria,2HTNT@201174|Actinobacteria,4ETQF@85013|Frankiales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
MMS3_k127_684112_2	204669.Acid345_3215	2.005e-21	96.0	COG0501@1|root,COG0501@2|Bacteria,3Y3FX@57723|Acidobacteria,2JHYR@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
MMS3_k127_684112_1	1121439.dsat_1904	3.876e-66	236.0	COG2227@1|root,COG2227@2|Bacteria,1QY93@1224|Proteobacteria,42VQY@68525|delta/epsilon subdivisions,2WRC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMS3_k127_684112_0	667014.Thein_1737	6.45e-90	308.0	COG0382@1|root,COG0382@2|Bacteria,2GI94@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
MMS3_k127_684112_3	1267534.KB906755_gene4092	1.554e-12	75.0	28P7U@1|root,2ZC21@2|Bacteria,3Y7PG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_689080_2	1267534.KB906757_gene1065	3.115e-49	181.0	COG3250@1|root,COG3250@2|Bacteria,3Y455@57723|Acidobacteria,2JHYM@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
MMS3_k127_689080_0	1267535.KB906767_gene377	4.497e-254	797.0	COG1472@1|root,COG1472@2|Bacteria,3Y3M7@57723|Acidobacteria,2JMBP@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
MMS3_k127_689080_1	1242864.D187_007030	1.202e-132	431.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_690384_0	1492738.FEM21_25670	1.619e-157	503.0	COG0620@1|root,COG0620@2|Bacteria,4PJ3I@976|Bacteroidetes,1IGBI@117743|Flavobacteriia,2NZR0@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_690384_1	1492738.FEM21_25680	1.821e-104	349.0	COG0451@1|root,COG0451@2|Bacteria,4NXEA@976|Bacteroidetes,1I65H@117743|Flavobacteriia	976|Bacteroidetes	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
MMS3_k127_690384_2	391625.PPSIR1_20459	1.653e-15	84.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMS3_k127_693554_3	312153.Pnuc_0082	1.252e-08	59.0	COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,2VXPX@28216|Betaproteobacteria,1KAY6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
MMS3_k127_693554_1	1037409.BJ6T_46260	1.505e-27	113.0	2E48M@1|root,32Z4G@2|Bacteria,1N6NZ@1224|Proteobacteria,2UH8Q@28211|Alphaproteobacteria,3K0JE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	MA20_36460	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_693554_2	456442.Mboo_1601	1.181e-11	78.0	COG3291@1|root,COG3391@1|root,arCOG02510@2157|Archaea,arCOG03563@2157|Archaea	2157|Archaea	P	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,NHL,PKD
MMS3_k127_693554_0	694427.Palpr_1196	1.526e-36	143.0	2EBPI@1|root,335PM@2|Bacteria,4NY9J@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_704631_2	204669.Acid345_4447	3.353e-106	359.0	COG2067@1|root,COG2067@2|Bacteria,3Y3JJ@57723|Acidobacteria,2JJB9@204432|Acidobacteriia	204432|Acidobacteriia	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
MMS3_k127_704631_0	1382359.JIAL01000001_gene2820	1.015e-313	992.0	2EXAB@1|root,33QKZ@2|Bacteria,3Y6WS@57723|Acidobacteria,2JMCR@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_704631_1	1267534.KB906757_gene1101	9.982e-110	368.0	COG2304@1|root,COG2304@2|Bacteria,3Y6RY@57723|Acidobacteria,2JMNT@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
MMS3_k127_70670_2	1121396.KB892907_gene4189	6.039e-31	125.0	COG4190@1|root,COG4190@2|Bacteria,1RDM2@1224|Proteobacteria,42UER@68525|delta/epsilon subdivisions,2WQDC@28221|Deltaproteobacteria,2MNYM@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_70670_3	998674.ATTE01000001_gene1043	1.378e-25	109.0	COG5652@1|root,COG5652@2|Bacteria,1RDK4@1224|Proteobacteria,1SA6N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_70670_0	207559.Dde_2493	0.0	1142.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2M96Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
MMS3_k127_70670_1	159450.NH14_30620	2.15e-45	171.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2VZNG@28216|Betaproteobacteria,1K6IW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	similarity to GP 3192745	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
MMS3_k127_706733_6	234267.Acid_5542	8.191e-25	104.0	COG0221@1|root,COG0221@2|Bacteria,3Y3UZ@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
MMS3_k127_706733_0	234267.Acid_0690	5.265e-214	691.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria	57723|Acidobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
MMS3_k127_706733_4	234267.Acid_5168	1.901e-43	160.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U4@57723|Acidobacteria	57723|Acidobacteria	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMS3_k127_706733_1	204669.Acid345_1186	1.796e-100	329.0	COG0717@1|root,COG0717@2|Bacteria,3Y42N@57723|Acidobacteria,2JIA0@204432|Acidobacteriia	204432|Acidobacteriia	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
MMS3_k127_706733_2	639030.JHVA01000001_gene2923	5.292e-91	320.0	COG0501@1|root,COG0501@2|Bacteria,3Y2PP@57723|Acidobacteria,2JI24@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
MMS3_k127_706733_3	208444.JNYY01000003_gene1734	1.547e-87	300.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4E032@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_706733_5	479434.Sthe_0904	2.208e-34	136.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_706904_0	1267535.KB906767_gene4955	1.541e-190	608.0	COG1501@1|root,COG1501@2|Bacteria,3Y35Y@57723|Acidobacteria,2JI95@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, clan GH-D	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2
MMS3_k127_706904_1	204669.Acid345_1561	1.687e-106	359.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria,2JIVB@204432|Acidobacteriia	204432|Acidobacteriia	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
MMS3_k127_706904_2	240015.ACP_3433	1.708e-82	276.0	COG0740@1|root,COG0740@2|Bacteria,3Y2SY@57723|Acidobacteria,2JHPB@204432|Acidobacteriia	204432|Acidobacteriia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_71343_2	1097668.BYI23_B002570	1.169e-154	499.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VNKT@28216|Betaproteobacteria,1KGZG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_23,Methyltransf_25,Methyltransf_31
MMS3_k127_71343_5	306281.AJLK01000109_gene3129	3.824e-93	312.0	COG1125@1|root,COG1125@2|Bacteria,1G21Q@1117|Cyanobacteria,1JKEV@1189|Stigonemataceae	1117|Cyanobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
MMS3_k127_71343_6	278963.ATWD01000001_gene1432	1.84e-74	257.0	COG1174@1|root,COG1174@2|Bacteria,3Y3BN@57723|Acidobacteria,2JI8U@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
MMS3_k127_71343_4	251229.Chro_2404	4.26e-99	332.0	COG1732@1|root,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,3VKKS@52604|Pleurocapsales	1117|Cyanobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
MMS3_k127_71343_3	479434.Sthe_2057	2.009e-131	433.0	COG0508@1|root,COG0508@2|Bacteria,2G7SG@200795|Chloroflexi,27XXQ@189775|Thermomicrobia	189775|Thermomicrobia	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_71343_0	1128421.JAGA01000003_gene3230	0.0	1027.0	COG0567@1|root,COG0567@2|Bacteria,2NQJV@2323|unclassified Bacteria	2|Bacteria	C	Dehydrogenase E1 component	sucA	GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
MMS3_k127_71343_1	525904.Tter_0267	9.426e-218	681.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_71343_7	386456.JQKN01000002_gene2701	1.32e-53	198.0	COG0500@1|root,arCOG04989@2157|Archaea,2Y796@28890|Euryarchaeota,23PJ6@183925|Methanobacteria	183925|Methanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_729088_7	1035184.HMPREF1042_2372	6.093e-06	48.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,42D2Y@671232|Streptococcus anginosus group	91061|Bacilli	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
MMS3_k127_729088_6	1163671.JAGI01000002_gene3778	1.723e-21	108.0	COG0412@1|root,COG0412@2|Bacteria,1UP2I@1239|Firmicutes,25H5P@186801|Clostridia,36PGN@31979|Clostridiaceae	186801|Clostridia	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_729088_1	1123242.JH636434_gene5547	2.824e-59	215.0	COG3836@1|root,COG3836@2|Bacteria	2|Bacteria	G	2-keto-3-deoxy-L-rhamnonate aldolase activity	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
MMS3_k127_729088_0	639030.JHVA01000001_gene590	1.542e-177	597.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_729088_4	471854.Dfer_3146	2.101e-35	157.0	COG2931@1|root,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
MMS3_k127_729088_5	157072.XP_008873997.1	2.262e-28	132.0	COG3914@1|root,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	OGT	GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
MMS3_k127_729088_3	1267535.KB906767_gene1404	9.083e-39	161.0	COG0457@1|root,COG0457@2|Bacteria,3Y6B0@57723|Acidobacteria	57723|Acidobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
MMS3_k127_729088_2	485917.Phep_3584	1.525e-51	204.0	COG4409@1|root,COG4409@2|Bacteria,4NT25@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
MMS3_k127_730096_9	351627.Csac_1145	5.975e-27	116.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,42EXZ@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMS3_k127_730096_2	1313265.JNIE01000003_gene1349	4.465e-127	417.0	COG0473@1|root,COG0473@2|Bacteria,2G3JN@200783|Aquificae	200783|Aquificae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS3_k127_730096_7	1198114.AciX9_0446	1.679e-29	124.0	COG1664@1|root,COG1664@2|Bacteria,3Y49V@57723|Acidobacteria,2JJ4E@204432|Acidobacteriia	204432|Acidobacteriia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMS3_k127_730096_11	234267.Acid_7804	1.134e-09	69.0	COG2948@1|root,COG2948@2|Bacteria,3Y6SY@57723|Acidobacteria	57723|Acidobacteria	U	multi-organism process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_730096_8	204669.Acid345_1523	1.016e-27	113.0	COG1278@1|root,COG1278@2|Bacteria,3Y57P@57723|Acidobacteria,2JJS8@204432|Acidobacteriia	204432|Acidobacteriia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_730096_6	273068.TTE1310	3.273e-39	152.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05505	NUDIX
MMS3_k127_730096_3	204669.Acid345_1001	1.043e-96	323.0	COG3279@1|root,COG3279@2|Bacteria,3Y3HR@57723|Acidobacteria,2JIXA@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
MMS3_k127_730096_0	42256.RradSPS_1755	2.433e-154	502.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
MMS3_k127_730096_4	1131269.AQVV01000010_gene2451	1.265e-83	288.0	COG0181@1|root,COG0181@2|Bacteria	2|Bacteria	H	hydroxymethylbilane synthase activity	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,2.5.1.61,4.2.1.75	ko:K01749,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iHN637.CLJU_RS15760,iPC815.YPO3849	Porphobil_deam,Porphobil_deamC
MMS3_k127_730096_1	204669.Acid345_2564	7.934e-133	435.0	COG0373@1|root,COG0373@2|Bacteria,3Y3DQ@57723|Acidobacteria,2JHR3@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
MMS3_k127_730096_5	338963.Pcar_3065	7.998e-48	184.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43SCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
MMS3_k127_730096_10	1150864.MILUP08_42229	3.561e-15	76.0	COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4D938@85008|Micromonosporales	201174|Actinobacteria	G	Phosphoglucomutase	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_730980_1	309803.CTN_1492	1.317e-90	317.0	COG0414@1|root,COG0414@2|Bacteria,2GC24@200918|Thermotogae	200918|Thermotogae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
MMS3_k127_730980_0	204669.Acid345_4746	1.782e-106	352.0	COG0413@1|root,COG0413@2|Bacteria,3Y3GX@57723|Acidobacteria,2JI6Y@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
MMS3_k127_730980_2	204669.Acid345_4748	1.636e-63	222.0	COG1428@1|root,COG1428@2|Bacteria,3Y759@57723|Acidobacteria,2JMB9@204432|Acidobacteriia	204432|Acidobacteriia	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
MMS3_k127_735510_0	1267535.KB906767_gene5454	9.858e-276	857.0	COG3408@1|root,COG3408@2|Bacteria,3Y6CR@57723|Acidobacteria,2JM5B@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_735510_1	743720.Psefu_2302	8.106e-25	114.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1YWC1@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	AI-2E family transporter	VP2476	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMS3_k127_748873_9	1267535.KB906767_gene688	5.482e-13	72.0	2EVWN@1|root,33PAB@2|Bacteria,3Y5UR@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_748873_1	204669.Acid345_1211	2.854e-126	418.0	COG0621@1|root,COG0621@2|Bacteria,3Y41R@57723|Acidobacteria,2JKPA@204432|Acidobacteriia	204432|Acidobacteriia	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
MMS3_k127_748873_6	204669.Acid345_1209	3.057e-43	160.0	2DIW1@1|root,32UBV@2|Bacteria,3Y5BC@57723|Acidobacteria,2JJSS@204432|Acidobacteriia	204432|Acidobacteriia	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
MMS3_k127_748873_7	204669.Acid345_1208	6.605e-24	102.0	COG0828@1|root,COG0828@2|Bacteria,3Y5J9@57723|Acidobacteria,2JJWG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
MMS3_k127_748873_4	204669.Acid345_2612	1.779e-47	179.0	COG0009@1|root,COG0009@2|Bacteria,3Y43Z@57723|Acidobacteria,2JI37@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
MMS3_k127_748873_5	204669.Acid345_2611	3.338e-44	168.0	COG1434@1|root,COG1434@2|Bacteria,3Y4FT@57723|Acidobacteria,2JJ4K@204432|Acidobacteriia	204432|Acidobacteriia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
MMS3_k127_748873_2	1157490.EL26_09635	4.754e-109	365.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,4HAYA@91061|Bacilli	91061|Bacilli	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
MMS3_k127_748873_0	1340493.JNIF01000003_gene1545	1.035e-283	899.0	COG0249@1|root,COG0249@2|Bacteria,3Y2J5@57723|Acidobacteria	57723|Acidobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
MMS3_k127_748873_3	1094508.Tsac_0936	3.198e-58	207.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,42G9G@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
MMS3_k127_748873_8	1382359.JIAL01000001_gene2110	6.15e-16	80.0	COG0268@1|root,COG0268@2|Bacteria,3Y5CZ@57723|Acidobacteria,2JJS9@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
MMS3_k127_748873_10	411459.RUMOBE_04030	5.509e-07	60.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3XZ4T@572511|Blautia	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
MMS3_k127_755710_14	1267535.KB906767_gene4101	4.595e-29	121.0	COG0389@1|root,COG0389@2|Bacteria,3Y3NY@57723|Acidobacteria,2JMMW@204432|Acidobacteriia	204432|Acidobacteriia	L	IMS family HHH motif	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
MMS3_k127_755710_1	234267.Acid_4618	6.02e-147	477.0	COG0617@1|root,COG0617@2|Bacteria,3Y3B8@57723|Acidobacteria	57723|Acidobacteria	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
MMS3_k127_755710_6	1356852.N008_01880	6.409e-81	281.0	COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,47JGE@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_755710_11	204669.Acid345_3290	6.493e-46	177.0	COG1322@1|root,COG1322@2|Bacteria	2|Bacteria	S	DNA recombination	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	Apolipoprotein
MMS3_k127_755710_9	204669.Acid345_2311	1.115e-62	236.0	2DKFZ@1|root,309D6@2|Bacteria,3Y5NS@57723|Acidobacteria,2JM02@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
MMS3_k127_755710_13	1267535.KB906767_gene1300	4.27e-32	135.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	CBM_6,Cadherin,DUF1929,HemolysinCabind,Malectin,Metallophos,PA14,Pur_ac_phosph_N
MMS3_k127_755710_8	266117.Rxyl_2624	9.845e-67	246.0	COG5298@1|root,COG5298@2|Bacteria,2GVU1@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334
MMS3_k127_755710_15	1379270.AUXF01000004_gene3040	7.553e-29	132.0	COG0457@1|root,COG0457@2|Bacteria	1379270.AUXF01000004_gene3040|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_755710_0	1121439.dsat_0477	5.408e-164	540.0	COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,43D6S@68525|delta/epsilon subdivisions,2X8DM@28221|Deltaproteobacteria,2MACQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM General secretory system II protein E domain protein	-	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_trans_2_3,T2SSE_N
MMS3_k127_755710_3	926569.ANT_02400	1.195e-137	450.0	COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
MMS3_k127_755710_17	1121007.AUML01000004_gene2496	0.0004827	44.0	COG1961@1|root,COG1961@2|Bacteria,4P6RD@976|Bacteroidetes,1IC2M@117743|Flavobacteriia	976|Bacteroidetes	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_755710_16	671143.DAMO_0141	4.311e-25	111.0	2EQC7@1|root,33HYA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_755710_7	880073.Calab_3149	6.791e-80	282.0	COG0301@1|root,COG0301@2|Bacteria,2NPBT@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
MMS3_k127_755710_5	234267.Acid_7390	3.12e-98	329.0	COG1028@1|root,COG1028@2|Bacteria,3Y6I4@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
MMS3_k127_755710_2	240015.ACP_0049	1.797e-144	474.0	COG1501@1|root,COG1501@2|Bacteria,3Y35Y@57723|Acidobacteria,2JI95@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, clan GH-D	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2,Melibiase_2_C
MMS3_k127_755710_12	1267535.KB906767_gene4838	7.317e-43	178.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
MMS3_k127_755710_4	401053.AciPR4_2256	3.309e-112	371.0	COG4975@1|root,COG4975@2|Bacteria,3Y7C0@57723|Acidobacteria,2JKXT@204432|Acidobacteriia	204432|Acidobacteriia	G	Ureide permease	-	-	-	ko:K05340	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Ureide_permease
MMS3_k127_755710_10	401053.AciPR4_2258	1.196e-49	177.0	COG1262@1|root,COG1262@2|Bacteria,3Y47J@57723|Acidobacteria,2JMIP@204432|Acidobacteriia	204432|Acidobacteriia	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
MMS3_k127_758098_2	234267.Acid_3555	1.022e-76	258.0	COG1915@1|root,COG1915@2|Bacteria,3Y7FB@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_758098_0	234267.Acid_3554	6.049e-111	370.0	COG2870@1|root,COG2870@2|Bacteria,3Y680@57723|Acidobacteria	57723|Acidobacteria	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
MMS3_k127_758098_7	278963.ATWD01000001_gene1623	5.386e-08	62.0	2EGII@1|root,33AAP@2|Bacteria,3Y5ST@57723|Acidobacteria,2JK57@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_758098_5	1005048.CFU_1854	1.687e-23	106.0	2E5QB@1|root,330EW@2|Bacteria,1N890@1224|Proteobacteria,2WC6A@28216|Betaproteobacteria,477UG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2844
MMS3_k127_758098_4	196367.JNFG01000004_gene5570	5.281e-74	267.0	28I2U@1|root,2Z86S@2|Bacteria,1P33F@1224|Proteobacteria,2VP36@28216|Betaproteobacteria,1K0WX@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3443)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3443
MMS3_k127_758098_6	1267533.KB906733_gene2896	5.019e-22	104.0	COG3678@1|root,COG3678@2|Bacteria,3Y5A6@57723|Acidobacteria,2JJQD@204432|Acidobacteriia	204432|Acidobacteriia	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
MMS3_k127_758098_1	234267.Acid_1101	8.246e-77	264.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_758098_3	234267.Acid_1102	4.101e-75	272.0	COG0642@1|root,COG2205@2|Bacteria,3Y4AU@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMS3_k127_762212_0	530564.Psta_2188	2.894e-90	316.0	COG2768@1|root,COG2768@2|Bacteria,2IXTH@203682|Planctomycetes	203682|Planctomycetes	C	conserved protein (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
MMS3_k127_76728_3	204669.Acid345_0644	0.0001356	48.0	COG0383@1|root,COG0383@2|Bacteria,3Y77D@57723|Acidobacteria,2JKQ2@204432|Acidobacteriia	204432|Acidobacteriia	G	Polysaccharide lyase family 4, domain III	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
MMS3_k127_76728_1	219305.MCAG_00296	1.383e-46	179.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
MMS3_k127_76728_0	1382359.JIAL01000001_gene2974	5.375e-71	248.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria,2JKP5@204432|Acidobacteriia	204432|Acidobacteriia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
MMS3_k127_76728_2	682795.AciX8_2702	3.445e-20	100.0	COG1802@1|root,COG1802@2|Bacteria,3Y849@57723|Acidobacteria,2JNAD@204432|Acidobacteriia	204432|Acidobacteriia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS3_k127_767648_0	204669.Acid345_4483	3.187e-86	312.0	COG4206@1|root,COG4206@2|Bacteria,3Y42S@57723|Acidobacteria,2JHUU@204432|Acidobacteriia	204432|Acidobacteriia	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_767648_2	118005.AWNK01000010_gene411	2.742e-07	57.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF4440,SnoaL_2,SnoaL_3,YkuD
MMS3_k127_767648_1	234267.Acid_2217	4.089e-61	219.0	COG0705@1|root,COG0705@2|Bacteria,3Y45U@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMS3_k127_767648_3	1047013.AQSP01000071_gene1939	6.716e-07	54.0	COG1297@1|root,COG1297@2|Bacteria,2NP0C@2323|unclassified Bacteria	2|Bacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
MMS3_k127_798809_0	234267.Acid_7054	5.827e-90	304.0	COG0077@1|root,COG0077@2|Bacteria,3Y49H@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
MMS3_k127_798809_3	378806.STAUR_8157	6.85e-50	186.0	COG1309@1|root,COG1309@2|Bacteria,1N9ZB@1224|Proteobacteria,42VC2@68525|delta/epsilon subdivisions,2WRA9@28221|Deltaproteobacteria,2YWGI@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_798809_5	479434.Sthe_3241	5.006e-14	80.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi,27XVP@189775|Thermomicrobia	189775|Thermomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_798809_2	1267534.KB906755_gene4130	1.096e-52	192.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601,ko:K05785	-	-	-	-	ko00000,ko03000,ko03009,ko03021	-	-	-	KOW,NusG
MMS3_k127_798809_4	1267535.KB906767_gene4038	7.224e-38	156.0	COG1596@1|root,COG1596@2|Bacteria,3Y7Z0@57723|Acidobacteria	57723|Acidobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
MMS3_k127_798809_1	682795.AciX8_1492	1.354e-72	263.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,3Y2V7@57723|Acidobacteria,2JIYH@204432|Acidobacteriia	57723|Acidobacteria	D	G-rich domain on putative tyrosine kinase	-	-	2.7.10.1	ko:K08252,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
MMS3_k127_8151_1	204669.Acid345_0085	1.105e-56	201.0	COG0774@1|root,COG0774@2|Bacteria,3Y40I@57723|Acidobacteria,2JI1R@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
MMS3_k127_8151_0	1267535.KB906767_gene5480	1.838e-220	713.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3Y3X3@57723|Acidobacteria,2JHXN@204432|Acidobacteriia	204432|Acidobacteriia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
MMS3_k127_8151_2	1185876.BN8_04643	1.09e-07	57.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,47S2U@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
MMS3_k127_82793_2	1267535.KB906767_gene2194	1.139e-15	81.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMS3_k127_82793_1	706587.Desti_0758	9.923e-31	135.0	COG0346@1|root,COG0346@2|Bacteria,1MWHG@1224|Proteobacteria,42WFT@68525|delta/epsilon subdivisions,2WRC3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
MMS3_k127_82793_0	240015.ACP_0864	5.638e-99	329.0	COG1874@1|root,COG1874@2|Bacteria,3Y65E@57723|Acidobacteria,2JKUI@204432|Acidobacteriia	204432|Acidobacteriia	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42M
MMS3_k127_83479_2	1267534.KB906757_gene887	4.01e-105	351.0	COG2204@1|root,COG2204@2|Bacteria,3Y4B7@57723|Acidobacteria,2JJ5G@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Sigma54_activat
MMS3_k127_83479_1	278963.ATWD01000001_gene2178	1.206e-121	405.0	COG2204@1|root,COG2204@2|Bacteria,3Y41F@57723|Acidobacteria,2JIZR@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_83479_3	765420.OSCT_1532	4.247e-33	140.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
MMS3_k127_83479_0	1267534.KB906757_gene1068	6.738e-304	945.0	COG1874@1|root,COG1874@2|Bacteria,3Y65E@57723|Acidobacteria,2JKUI@204432|Acidobacteriia	204432|Acidobacteriia	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42M
MMS3_k127_843455_1	926566.Terro_1634	7.646e-101	337.0	COG4591@1|root,COG4591@2|Bacteria,3Y3BU@57723|Acidobacteria,2JIC6@204432|Acidobacteriia	204432|Acidobacteriia	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
MMS3_k127_843455_2	926566.Terro_1489	1.025e-73	255.0	COG1136@1|root,COG1136@2|Bacteria,3Y412@57723|Acidobacteria,2JIJG@204432|Acidobacteriia	204432|Acidobacteriia	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
MMS3_k127_843455_0	234267.Acid_2278	1.23e-127	410.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS3_k127_8506_4	1267535.KB906767_gene2582	2.972e-09	65.0	COG0438@1|root,COG0438@2|Bacteria,3Y68S@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_8506_2	204669.Acid345_3269	3.904e-126	417.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HZ@57723|Acidobacteria,2JI47@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_8506_0	204669.Acid345_3274	4.174e-164	530.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_8506_1	204669.Acid345_3275	1.773e-137	458.0	COG5000@1|root,COG5000@2|Bacteria,3Y32Z@57723|Acidobacteria,2JP5E@204432|Acidobacteriia	204432|Acidobacteriia	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMS3_k127_8506_3	1123503.KB908057_gene2691	6.945e-12	70.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria,2KFD1@204458|Caulobacterales	204458|Caulobacterales	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
MMS3_k127_87505_0	204669.Acid345_4675	0.0	1251.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria,2JIW0@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMS3_k127_87505_6	906968.Trebr_0917	2.362e-21	101.0	2EH48@1|root,33AW7@2|Bacteria,2J921@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_87505_3	1121413.JMKT01000001_gene1686	1.917e-39	151.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2X245@28221|Deltaproteobacteria,2MFSC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMS3_k127_87505_1	204669.Acid345_0501	3.828e-183	584.0	COG0154@1|root,COG0154@2|Bacteria,3Y2PE@57723|Acidobacteria,2JIE0@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_87505_5	204669.Acid345_0499	2.309e-21	98.0	COG0721@1|root,COG0721@2|Bacteria,3Y5QA@57723|Acidobacteria,2JNA0@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
MMS3_k127_87505_7	710696.Intca_0005	6.77e-09	62.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FGYZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
MMS3_k127_87505_2	1267533.KB906740_gene361	2.13e-53	194.0	COG0424@1|root,COG0424@2|Bacteria,3Y4ZU@57723|Acidobacteria,2JJH8@204432|Acidobacteriia	204432|Acidobacteriia	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
MMS3_k127_87505_4	204669.Acid345_4628	4.831e-31	124.0	COG3276@1|root,COG3276@2|Bacteria,3Y6R2@57723|Acidobacteria,2JKPY@204432|Acidobacteriia	204432|Acidobacteriia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,SelB-wing_3
MMS3_k127_878227_2	1128421.JAGA01000001_gene2163	2.903e-20	98.0	COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19,1.4.5.1	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	-	R01374,R07463,R09493	RC00006,RC00025,RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_878227_1	756067.MicvaDRAFT_5190	2.647e-35	144.0	COG0546@1|root,COG0546@2|Bacteria,1G9QT@1117|Cyanobacteria,1HEX3@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMS3_k127_878227_0	234267.Acid_5364	8.546e-40	156.0	2EGFY@1|root,30MEN@2|Bacteria,3Y7VF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_878227_3	525282.HMPREF0391_11569	2.612e-10	64.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,22G2X@1570339|Peptoniphilaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
MMS3_k127_894001_3	204669.Acid345_1951	1.166e-41	154.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria,2JII1@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMS3_k127_894001_4	643473.KB235930_gene3128	1.14e-25	108.0	2CCSR@1|root,32RWC@2|Bacteria,1G8SI@1117|Cyanobacteria,1HP5C@1161|Nostocales	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMS3_k127_894001_2	1162668.LFE_1641	4.661e-64	225.0	COG0652@1|root,COG0652@2|Bacteria,3J18H@40117|Nitrospirae	40117|Nitrospirae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
MMS3_k127_894001_1	1429916.X566_21020	2.627e-74	258.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
MMS3_k127_894001_6	9785.ENSLAFP00000008727	0.0002932	45.0	COG2355@1|root,KOG4127@2759|Eukaryota,38D9H@33154|Opisthokonta,3BCAM@33208|Metazoa,3CRIG@33213|Bilateria,485B5@7711|Chordata,48UW4@7742|Vertebrata,3JDF0@40674|Mammalia,34UKQ@311790|Afrotheria	33208|Metazoa	O	dipeptidase 2	DPEP2	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0016805,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMS3_k127_894001_0	1382359.JIAL01000001_gene176	1.271e-211	664.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria,2JIPN@204432|Acidobacteriia	204432|Acidobacteriia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
MMS3_k127_894001_5	204669.Acid345_2261	5.099e-22	110.0	COG2304@1|root,COG2304@2|Bacteria,3Y98T@57723|Acidobacteria,2JP5A@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_929921_0	204669.Acid345_0762	2.074e-266	838.0	COG1529@1|root,COG1529@2|Bacteria,3Y2ME@57723|Acidobacteria,2JIZI@204432|Acidobacteriia	204432|Acidobacteriia	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_929921_2	1267535.KB906767_gene4795	5.25e-57	205.0	COG2080@1|root,COG2080@2|Bacteria,3Y4DP@57723|Acidobacteria,2JJ2F@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S -binding	-	-	-	ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002	-	-	-	Fer2,Fer2_2,TAT_signal
MMS3_k127_929921_1	243231.GSU1611	6.645e-194	622.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43T46@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K07788,ko:K07789,ko:K18138	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
MMS3_k127_93023_0	204669.Acid345_4390	1.234e-113	377.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
MMS3_k127_93023_1	1300345.LF41_1439	3.677e-17	93.0	2E5BX@1|root,3303Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_935906_4	986075.CathTA2_1711	3.338e-33	133.0	COG0007@1|root,COG0007@2|Bacteria,1TQNH@1239|Firmicutes,4HBB7@91061|Bacilli	91061|Bacilli	H	Belongs to the precorrin methyltransferase family	hemX	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
MMS3_k127_935906_2	682795.AciX8_2515	6.815e-53	188.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
MMS3_k127_935906_1	1267535.KB906767_gene3668	8.623e-131	440.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738,Peptidase_M56
MMS3_k127_935906_3	1267534.KB906758_gene2527	2.946e-48	184.0	COG2027@1|root,COG2027@2|Bacteria,3Y7ZS@57723|Acidobacteria,2JMZE@204432|Acidobacteriia	204432|Acidobacteriia	M	Protein of unknown function (DUF3738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738
MMS3_k127_935906_0	1267535.KB906767_gene3671	2.03e-145	473.0	COG1629@1|root,COG4771@2|Bacteria,3Y6A1@57723|Acidobacteria,2JKK3@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_949712_0	278963.ATWD01000003_gene34	1.302e-283	907.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_949712_3	1122605.KB893625_gene2136	5.441e-107	371.0	COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,1IWFX@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
MMS3_k127_949712_8	946235.CAER01000054_gene2863	4.846e-40	161.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,23IWY@182709|Oceanobacillus	91061|Bacilli	GK	ROK family	glcK	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07790	ROK
MMS3_k127_949712_9	304371.MCP_0275	5.747e-24	112.0	COG2140@1|root,arCOG02602@2157|Archaea,2XWS8@28890|Euryarchaeota,2N9IM@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM Glucose-6-phosphate isomerase	gpi	-	5.3.1.9	ko:K06859	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	GPI
MMS3_k127_949712_7	553973.CLOHYLEM_05709	4.248e-47	177.0	COG1878@1|root,COG1878@2|Bacteria,1V34U@1239|Firmicutes,248XJ@186801|Clostridia,21XGM@1506553|Lachnoclostridium	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMS3_k127_949712_4	697303.Thewi_1630	2.301e-105	351.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia,42ENM@68295|Thermoanaerobacterales	186801|Clostridia	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMS3_k127_949712_5	1449044.JMLE01000018_gene1696	3.189e-100	339.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
MMS3_k127_949712_10	760011.Spico_1653	2.891e-14	75.0	COG0508@1|root,COG0508@2|Bacteria,2J686@203691|Spirochaetes	203691|Spirochaetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_949712_1	697281.Mahau_1207	4.058e-205	655.0	COG2730@1|root,COG2730@2|Bacteria,1V9GI@1239|Firmicutes,24KYA@186801|Clostridia	186801|Clostridia	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
MMS3_k127_949712_6	869213.JCM21142_104195	3.767e-61	224.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,47J9W@768503|Cytophagia	976|Bacteroidetes	EG	PFAM RhaT l-rhamnose-proton symport 2	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
MMS3_k127_949712_2	666509.RCA23_c23460	1.754e-144	470.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2UNXP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	rhmD	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_969994_3	1382359.JIAL01000001_gene1920	4.128e-65	229.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
MMS3_k127_969994_0	240015.ACP_2642	5.888e-137	460.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y6NA@57723|Acidobacteria,2JKSZ@204432|Acidobacteriia	204432|Acidobacteriia	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
MMS3_k127_969994_2	682795.AciX8_4855	7.89e-71	250.0	28JM9@1|root,2Z9DT@2|Bacteria,3Y2S6@57723|Acidobacteria,2JIQX@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_969994_4	240015.ACP_2367	4.71e-30	130.0	28IHN@1|root,2Z8IV@2|Bacteria,3Y3Y5@57723|Acidobacteria,2JIXQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
MMS3_k127_969994_5	404589.Anae109_1578	1.375e-16	81.0	2AG2N@1|root,31670@2|Bacteria,1NNB1@1224|Proteobacteria,437DW@68525|delta/epsilon subdivisions,2X2K1@28221|Deltaproteobacteria,2Z2S0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_969994_6	684949.ATTJ01000001_gene1364	1.39e-05	57.0	2DPH7@1|root,3322P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Imm_superinfect,PG_binding_1
MMS3_k127_969994_1	234267.Acid_0914	4.717e-82	281.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_99665_1	335543.Sfum_1285	2.716e-82	288.0	COG1150@1|root,COG1150@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2MRY0@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
MMS3_k127_99665_0	387631.Asulf_02109	1.004e-274	863.0	COG1148@1|root,COG1908@1|root,arCOG02235@2157|Archaea,arCOG02476@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
MMS3_k127_99665_2	485916.Dtox_3576	2.243e-11	66.0	COG1148@1|root,COG1148@2|Bacteria,1TS8Y@1239|Firmicutes,24CXD@186801|Clostridia,2604G@186807|Peptococcaceae	186801|Clostridia	C	binding domain	-	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,Fer4,Fer4_10,Fer4_7,Fer4_9,NAD_binding_8,Pyr_redox_2
## 2240 queries scanned
## Total time (seconds): 152.77050828933716
## Rate: 14.66 q/s