## Fri Nov 15 21:39:04 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin17/MMS_3_bin.64.fa -m mmseqs --itype genome -o MMS_3_bin.64 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/MMS_3_bin.64 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
MMS3_k127_1018957_9	1449347.JQLN01000005_gene4748	0.0002535	46.0	COG2026@1|root,COG2026@2|Bacteria,2IN19@201174|Actinobacteria,2M3XI@2063|Kitasatospora	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
MMS3_k127_1018957_7	525909.Afer_1166	9.303e-05	49.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	relF	GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141	2.3.1.15	ko:K08591,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	PhdYeFM_antitox
MMS3_k127_1018957_3	1380390.JIAT01000010_gene4371	3.632e-55	200.0	COG0671@1|root,COG0671@2|Bacteria,2HQWJ@201174|Actinobacteria,4CSPJ@84995|Rubrobacteria	84995|Rubrobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
MMS3_k127_1018957_4	929712.KI912613_gene4505	4.357e-53	200.0	COG1376@1|root,COG1376@2|Bacteria,2HQX3@201174|Actinobacteria,4CSPQ@84995|Rubrobacteria	84995|Rubrobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_1018957_5	1229780.BN381_220003	1.899e-29	126.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
MMS3_k127_1018957_2	469383.Cwoe_1890	6.681e-86	300.0	COG1363@1|root,COG1363@2|Bacteria,2I6I7@201174|Actinobacteria	201174|Actinobacteria	G	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_1018957_0	345341.KUTG_03807	2.288e-140	452.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4DY2W@85010|Pseudonocardiales	201174|Actinobacteria	L	Exodeoxyribonuclease III xth	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
MMS3_k127_1018957_1	1306174.JODP01000019_gene4612	9.094e-102	350.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
MMS3_k127_1065713_0	469383.Cwoe_1337	0.0	1089.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CPGY@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_1065713_1	1380390.JIAT01000011_gene2586	2.113e-239	743.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CPE9@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMS3_k127_1065713_19	929712.KI912613_gene4947	6.745e-59	209.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4CQFD@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
MMS3_k127_1065713_8	1380390.JIAT01000011_gene2588	5.763e-95	314.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CPFD@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
MMS3_k127_1065713_17	1283299.AUKG01000001_gene2632	8.104e-66	233.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CPXR@84995|Rubrobacteria	84995|Rubrobacteria	J	50S ribosomal protein L4	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
MMS3_k127_1065713_26	1122939.ATUD01000003_gene3568	1.713e-38	153.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4CQIU@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
MMS3_k127_1065713_4	469383.Cwoe_1343	5.007e-155	492.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CPEQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
MMS3_k127_1065713_24	929712.KI912613_gene4942	1.188e-40	154.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CQEC@84995|Rubrobacteria	84995|Rubrobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
MMS3_k127_1065713_22	469383.Cwoe_1345	2.77e-45	173.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4CQP9@84995|Rubrobacteria	84995|Rubrobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
MMS3_k127_1065713_5	469383.Cwoe_1346	6.927e-127	414.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CPWK@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
MMS3_k127_1065713_15	1380390.JIAT01000011_gene2595	1.929e-70	243.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4CQ15@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
MMS3_k127_1065713_31	1380390.JIAT01000011_gene2596	7.805e-12	76.0	COG0255@1|root,COG0255@2|Bacteria,2HPC6@201174|Actinobacteria,4CQQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
MMS3_k127_1065713_25	469383.Cwoe_1349	2.618e-39	155.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4CQJP@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
MMS3_k127_1065713_18	469383.Cwoe_1350	2.405e-61	216.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CQ56@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
MMS3_k127_1065713_28	469383.Cwoe_1351	2.244e-26	117.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4CQNC@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
MMS3_k127_1065713_12	469383.Cwoe_1352	6.655e-86	290.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CQ45@84995|Rubrobacteria	84995|Rubrobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
MMS3_k127_1065713_27	469383.Cwoe_1353	1.804e-28	115.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CQKA@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
MMS3_k127_1065713_20	1283299.AUKG01000001_gene2645	7.201e-54	192.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4CQGZ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
MMS3_k127_1065713_11	469383.Cwoe_1355	7.887e-87	290.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CQ44@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
MMS3_k127_1065713_23	1283299.AUKG01000001_gene2647	8.244e-43	161.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4CQBN@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
MMS3_k127_1065713_13	469383.Cwoe_1357	3.096e-83	288.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CPMN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
MMS3_k127_1065713_29	469383.Cwoe_1358	7.751e-18	87.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4CQVX@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
MMS3_k127_1065713_14	469383.Cwoe_1359	1.938e-72	249.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CQD8@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
MMS3_k127_1065713_2	1283299.AUKG01000001_gene2652	1.63e-213	669.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CPTT@84995|Rubrobacteria	84995|Rubrobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
MMS3_k127_1065713_9	469383.Cwoe_1361	2.768e-92	308.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CP9X@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMS3_k127_1065713_10	477641.MODMU_4673	6.805e-92	320.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4ESA1@85013|Frankiales	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	tgs3	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_1065713_6	1283299.AUKG01000001_gene2654	2.118e-110	364.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CPA2@84995|Rubrobacteria	84995|Rubrobacteria	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMS3_k127_1065713_30	469383.Cwoe_1363	4.776e-14	72.0	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
MMS3_k127_1065713_21	1122939.ATUD01000003_gene3589	4.398e-53	190.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4CQ8S@84995|Rubrobacteria	84995|Rubrobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
MMS3_k127_1065713_16	1283299.AUKG01000001_gene2656	2.949e-68	233.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4CPZ7@84995|Rubrobacteria	84995|Rubrobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
MMS3_k127_1065713_7	1380390.JIAT01000011_gene2614	4.111e-110	360.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CQ5S@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
MMS3_k127_1065713_3	1380390.JIAT01000011_gene2615	3.492e-174	550.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CPU6@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
MMS3_k127_1071847_19	1283299.AUKG01000002_gene3936	6.717e-143	464.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4CP6W@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
MMS3_k127_1071847_25	469383.Cwoe_4594	4.089e-89	302.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4CU2Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Quinolinate phosphoribosyl transferase, C-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
MMS3_k127_1071847_10	469383.Cwoe_4596	1.44e-164	523.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CPCP@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMS3_k127_1071847_2	390989.JOEG01000026_gene1546	6.548e-262	838.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4D8X2@85008|Micromonosporales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
MMS3_k127_1071847_40	469383.Cwoe_4600	2.049e-30	127.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CQU6@84995|Rubrobacteria	84995|Rubrobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
MMS3_k127_1071847_12	469383.Cwoe_4603	1.152e-155	498.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPY2@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
MMS3_k127_1071847_3	469383.Cwoe_4610	9.024e-261	810.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4CPPC@84995|Rubrobacteria	84995|Rubrobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMS3_k127_1071847_13	1283299.AUKG01000002_gene3901	1.035e-151	497.0	COG2222@1|root,COG2222@2|Bacteria,2IN5A@201174|Actinobacteria,4CP71@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
MMS3_k127_1071847_18	1380390.JIAT01000009_gene330	1.419e-147	479.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPFB@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
MMS3_k127_1071847_5	1380390.JIAT01000009_gene331	7.967e-210	659.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4CPRS@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_1071847_41	1380390.JIAT01000009_gene339	2.342e-29	119.0	COG0355@1|root,COG0355@2|Bacteria,2HPEY@201174|Actinobacteria,4CQTA@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
MMS3_k127_1071847_7	1321778.HMPREF1982_04479	9.193e-205	648.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,268HM@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
MMS3_k127_1071847_22	1283299.AUKG01000002_gene3889	5.745e-109	362.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CPD1@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
MMS3_k127_1071847_1	469383.Cwoe_4620	1.282e-270	842.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CP6C@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
MMS3_k127_1071847_29	1283299.AUKG01000002_gene3887	9.676e-70	246.0	COG0712@1|root,COG0712@2|Bacteria,2HNXP@201174|Actinobacteria,4CQ6B@84995|Rubrobacteria	84995|Rubrobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
MMS3_k127_1071847_38	1380390.JIAT01000009_gene344	1.577e-44	170.0	COG0711@1|root,COG0711@2|Bacteria,2HGFF@201174|Actinobacteria,4CQKE@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
MMS3_k127_1071847_43	929712.KI912613_gene2876	3.418e-24	104.0	COG0636@1|root,COG0636@2|Bacteria,2HPGR@201174|Actinobacteria,4CQV2@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
MMS3_k127_1071847_28	929712.KI912613_gene2875	5.431e-74	265.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CR6B@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase A chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_A
MMS3_k127_1071847_37	1449347.JQLN01000007_gene1859	2.106e-46	179.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,2M24A@2063|Kitasatospora	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
MMS3_k127_1071847_31	1380390.JIAT01000015_gene5725	1.294e-59	216.0	COG0726@1|root,COG0726@2|Bacteria,2GMC2@201174|Actinobacteria,4CQU1@84995|Rubrobacteria	84995|Rubrobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
MMS3_k127_1071847_32	1380390.JIAT01000015_gene5724	1.607e-56	209.0	2B721@1|root,3202S@2|Bacteria,2HRGC@201174|Actinobacteria,4CTFP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1071847_33	469383.Cwoe_1550	5.839e-55	216.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
MMS3_k127_1071847_39	929712.KI912613_gene3385	8.646e-32	146.0	2DKYN@1|root,30WXH@2|Bacteria,2HQHS@201174|Actinobacteria,4CS33@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS3_k127_1071847_16	1283299.AUKG01000002_gene3868	1.094e-149	486.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CQIN@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase, family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
MMS3_k127_1071847_4	1380390.JIAT01000009_gene366	1.76e-210	663.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4CPC6@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
MMS3_k127_1071847_34	1380390.JIAT01000009_gene368	8.067e-53	194.0	COG0009@1|root,COG0009@2|Bacteria,2HPE4@201174|Actinobacteria,4CQS7@84995|Rubrobacteria	84995|Rubrobacteria	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
MMS3_k127_1071847_27	1380390.JIAT01000009_gene369	7.896e-79	273.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CQFI@84995|Rubrobacteria	84995|Rubrobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
MMS3_k127_1071847_9	1283299.AUKG01000002_gene3861	5.901e-171	542.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CP8A@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMS3_k127_1071847_20	1283299.AUKG01000002_gene3860	9.09e-143	466.0	COG3872@1|root,COG3872@2|Bacteria,2IIWY@201174|Actinobacteria,4CPJY@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
MMS3_k127_1071847_42	469383.Cwoe_4636	1.448e-28	116.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CQSQ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
MMS3_k127_1071847_44	1283299.AUKG01000002_gene3858	1.182e-11	73.0	COG1572@1|root,COG1572@2|Bacteria,2HPER@201174|Actinobacteria,4CQSZ@84995|Rubrobacteria	84995|Rubrobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
MMS3_k127_1071847_0	469383.Cwoe_4638	1.505e-317	978.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,2HQ59@201174|Actinobacteria,4CRNF@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2
MMS3_k127_1071847_17	1380390.JIAT01000009_gene375	2.567e-148	478.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CPAU@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
MMS3_k127_1071847_21	469383.Cwoe_4640	1.46e-135	434.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4CPQ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
MMS3_k127_1071847_30	469383.Cwoe_4641	7.796e-69	237.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4CQ6D@84995|Rubrobacteria	84995|Rubrobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
MMS3_k127_1071847_26	469383.Cwoe_4644	2.63e-88	299.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4CRTI@84995|Rubrobacteria	84995|Rubrobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
MMS3_k127_1071847_6	1380390.JIAT01000009_gene387	1.552e-206	651.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CPNX@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_1071847_11	469383.Cwoe_4642	3.796e-159	516.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CPVK@84995|Rubrobacteria	84995|Rubrobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
MMS3_k127_1071847_8	469383.Cwoe_0232	1.205e-200	631.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4CPRK@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1071847_36	710685.MycrhN_4941	1.358e-46	177.0	COG3000@1|root,COG3000@2|Bacteria,2HR3N@201174|Actinobacteria,234PY@1762|Mycobacteriaceae	201174|Actinobacteria	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
MMS3_k127_1071847_35	101510.RHA1_ro11052	2.162e-50	190.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,4G388@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_1071847_15	469383.Cwoe_4647	3.141e-150	481.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CQB3@84995|Rubrobacteria	84995|Rubrobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
MMS3_k127_1071847_24	1283299.AUKG01000002_gene3826	1.082e-92	315.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CR4C@84995|Rubrobacteria	84995|Rubrobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
MMS3_k127_1071847_14	469383.Cwoe_4653	1.853e-150	496.0	COG1543@1|root,COG1543@2|Bacteria,2GKTI@201174|Actinobacteria,4CRV4@84995|Rubrobacteria	84995|Rubrobacteria	G	Domain of unknown function (DUF1957)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1957,Glyco_hydro_57
MMS3_k127_1071847_23	469383.Cwoe_4654	4.139e-99	329.0	COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,4CP67@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMS3_k127_1080306_6	235985.BBPN01000014_gene5373	2.045e-55	201.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,2NGCN@228398|Streptacidiphilus	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
MMS3_k127_1080306_8	1283299.AUKG01000002_gene5287	3.021e-49	180.0	COG0393@1|root,COG0393@2|Bacteria,2IHTU@201174|Actinobacteria,4CTA5@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
MMS3_k127_1080306_11	882083.SacmaDRAFT_1458	3.205e-29	129.0	COG1309@1|root,COG1309@2|Bacteria,2IP2Y@201174|Actinobacteria,4E5PB@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1080306_0	1380390.JIAT01000009_gene1397	9.633e-166	569.0	COG0433@1|root,COG0433@2|Bacteria,2HPNI@201174|Actinobacteria,4CR0S@84995|Rubrobacteria	84995|Rubrobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1080306_10	469383.Cwoe_3789	1.174e-44	176.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CS4E@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1080306_7	1123252.ATZF01000007_gene276	2.881e-52	207.0	COG0433@1|root,COG0433@2|Bacteria,1UY1K@1239|Firmicutes,4INNW@91061|Bacilli,27D69@186824|Thermoactinomycetaceae	91061|Bacilli	S	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
MMS3_k127_1080306_4	1283299.AUKG01000004_gene1228	3.781e-59	209.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4CSAG@84995|Rubrobacteria	84995|Rubrobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
MMS3_k127_1080306_9	469383.Cwoe_2841	1.999e-47	173.0	COG2030@1|root,COG2030@2|Bacteria,2HR1S@201174|Actinobacteria,4CSW6@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMS3_k127_1080306_2	1380390.JIAT01000016_gene5635	2.614e-119	393.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CP6H@84995|Rubrobacteria	84995|Rubrobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
MMS3_k127_1080306_1	1380390.JIAT01000016_gene5634	7.587e-152	489.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CP6R@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS3_k127_1080306_3	469383.Cwoe_2844	2.291e-77	276.0	COG2264@1|root,COG2264@2|Bacteria,2GW3S@201174|Actinobacteria,4CP8H@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
MMS3_k127_1080306_5	1122939.ATUD01000005_gene2788	2.105e-56	210.0	COG2159@1|root,COG2159@2|Bacteria,2HJ7X@201174|Actinobacteria,4CPK2@84995|Rubrobacteria	84995|Rubrobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS3_k127_1098395_7	1283299.AUKG01000001_gene2962	1.073e-60	213.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4CQHT@84995|Rubrobacteria	84995|Rubrobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
MMS3_k127_1098395_1	469383.Cwoe_1691	2.276e-185	594.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CP99@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
MMS3_k127_1098395_6	469383.Cwoe_1692	3.504e-76	263.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CPWF@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
MMS3_k127_1098395_3	1380390.JIAT01000014_gene6270	2.063e-108	356.0	COG1595@1|root,COG1595@2|Bacteria,2HQ0U@201174|Actinobacteria,4CRGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1098395_14	1463820.JOGW01000008_gene1348	1.573e-07	61.0	COG3247@1|root,COG3247@2|Bacteria,2GP9Y@201174|Actinobacteria	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
MMS3_k127_1098395_0	710111.FraQA3DRAFT_4077	8.877e-217	684.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4EU4R@85013|Frankiales	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1098395_9	1283299.AUKG01000001_gene2476	7.934e-53	190.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1098395_4	1380390.JIAT01000011_gene2334	9.513e-97	333.0	28MY8@1|root,32YD0@2|Bacteria,2HR9A@201174|Actinobacteria,4CT5U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1098395_2	1382356.JQMP01000003_gene1765	5.847e-129	432.0	COG3118@1|root,COG3118@2|Bacteria,2G8FS@200795|Chloroflexi	200795|Chloroflexi	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
MMS3_k127_1098395_8	1229780.BN381_130166	1.556e-55	201.0	2DCZU@1|root,2ZFYS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1098395_5	1380390.JIAT01000014_gene6257	1.217e-83	281.0	COG1595@1|root,COG1595@2|Bacteria,2HG39@201174|Actinobacteria,4CP8K@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1098395_12	1380390.JIAT01000014_gene6256	5.865e-26	110.0	2AWQX@1|root,31NMV@2|Bacteria,2HR6S@201174|Actinobacteria,4CT2Q@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1098395_11	1283299.AUKG01000001_gene3040	8.165e-30	119.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CQ6Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
MMS3_k127_110493_6	1380390.JIAT01000009_gene2062	3.958e-135	438.0	COG3481@1|root,COG3481@2|Bacteria,2IRFS@201174|Actinobacteria,4CPMU@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD
MMS3_k127_110493_9	118173.KB235914_gene1739	1.207e-91	315.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,SEFIR,TIR_2
MMS3_k127_110493_1	1380390.JIAT01000009_gene2059	2.919e-314	979.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4CPJ7@84995|Rubrobacteria	84995|Rubrobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
MMS3_k127_110493_16	469383.Cwoe_4246	3.162e-17	86.0	COG1734@1|root,COG1734@2|Bacteria,2HRXB@201174|Actinobacteria,4CU0F@84995|Rubrobacteria	84995|Rubrobacteria	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
MMS3_k127_110493_4	76636.JOEC01000004_gene1338	1.085e-164	528.0	COG0017@1|root,COG0017@2|Bacteria,2I2KQ@201174|Actinobacteria,4FKWR@85023|Microbacteriaceae	201174|Actinobacteria	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS3_k127_110493_0	471852.Tcur_1701	0.0	1065.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4EIDQ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
MMS3_k127_110493_13	1380390.JIAT01000009_gene964	6.137e-28	122.0	COG0776@1|root,COG0776@2|Bacteria,2HN5Q@201174|Actinobacteria,4CT7S@84995|Rubrobacteria	84995|Rubrobacteria	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
MMS3_k127_110493_10	469383.Cwoe_4256	8.35e-90	309.0	COG0715@1|root,COG0715@2|Bacteria,2HPRB@201174|Actinobacteria,4CR4H@84995|Rubrobacteria	84995|Rubrobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
MMS3_k127_110493_2	469383.Cwoe_0843	1.737e-262	821.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
MMS3_k127_110493_7	1382356.JQMP01000003_gene1765	5.042e-128	436.0	COG3118@1|root,COG3118@2|Bacteria,2G8FS@200795|Chloroflexi	200795|Chloroflexi	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
MMS3_k127_110493_17	1120936.KB907218_gene3287	7.852e-13	81.0	COG1309@1|root,COG1309@2|Bacteria,2IP2Y@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_110493_14	1283299.AUKG01000002_gene5038	5.032e-27	127.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_110493_15	1283283.ATXA01000005_gene2099	2.385e-20	101.0	2B189@1|root,31TNP@2|Bacteria,2GSQX@201174|Actinobacteria	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
MMS3_k127_110493_3	1122939.ATUD01000006_gene1796	8.365e-187	598.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4CPEP@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_110493_5	1380390.JIAT01000017_gene5370	9.473e-149	477.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria,4CQ3T@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_110493_12	1123393.KB891326_gene35	1.027e-51	190.0	COG0491@1|root,COG0491@2|Bacteria,1NMU0@1224|Proteobacteria,2WBU4@28216|Betaproteobacteria,1KSJV@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_110493_11	1123023.JIAI01000001_gene7527	2.084e-82	289.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4E93D@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_110493_8	1054213.HMPREF9946_00831	1.759e-125	420.0	COG0174@1|root,COG0174@2|Bacteria,1MXPK@1224|Proteobacteria,2TUHR@28211|Alphaproteobacteria,2JPM1@204441|Rhodospirillales	204441|Rhodospirillales	E	Glutamine synthetase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Gln-synt_C,Gln-synt_N_2
MMS3_k127_110493_18	882083.SacmaDRAFT_2273	6.782e-10	63.0	2EZP7@1|root,33SU8@2|Bacteria,2H4B7@201174|Actinobacteria,4EAP8@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1128080_10	926566.Terro_1722	3.924e-42	176.0	COG0438@1|root,COG0438@2|Bacteria,3Y4F9@57723|Acidobacteria,2JJ5D@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1128080_8	1133849.O3I_014975	1.506e-63	242.0	COG0438@1|root,COG0438@2|Bacteria,2IA7N@201174|Actinobacteria,4FVJ1@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_1128080_4	91464.S7335_5529	8.018e-79	276.0	2EWWG@1|root,33Q7V@2|Bacteria	2|Bacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
MMS3_k127_1128080_12	118161.KB235922_gene3732	2.412e-33	145.0	COG4424@1|root,COG4424@2|Bacteria,1G29K@1117|Cyanobacteria,3VJFW@52604|Pleurocapsales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
MMS3_k127_1128080_16	1380390.JIAT01000011_gene2627	2.33e-26	122.0	COG4733@1|root,COG4733@2|Bacteria,2HNSD@201174|Actinobacteria,4CSA3@84995|Rubrobacteria	84995|Rubrobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1128080_0	468556.AQYG01000042_gene2156	8.733e-227	721.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4GAAD@85026|Gordoniaceae	201174|Actinobacteria	H	Catalyzes the synthesis of activated sulfate	cysN	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
MMS3_k127_1128080_14	1283299.AUKG01000002_gene4060	1.639e-32	133.0	29Z0D@1|root,30KXH@2|Bacteria,2HP8W@201174|Actinobacteria,4CQM4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1128080_2	1283299.AUKG01000002_gene4044	1.631e-90	324.0	COG3511@1|root,COG3511@2|Bacteria,2IC2P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
MMS3_k127_1128080_5	561175.KB894093_gene2983	1.277e-73	258.0	COG0730@1|root,COG0730@2|Bacteria,2GNW8@201174|Actinobacteria,4EGSD@85012|Streptosporangiales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_1128080_3	1160137.KB907308_gene6974	6.722e-86	293.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4FUNV@85025|Nocardiaceae	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
MMS3_k127_1128080_7	1380390.JIAT01000010_gene4805	3.138e-64	234.0	COG0668@1|root,COG0668@2|Bacteria,2IQWA@201174|Actinobacteria,4CSFW@84995|Rubrobacteria	84995|Rubrobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
MMS3_k127_1128080_11	469383.Cwoe_4689	8.179e-34	144.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,4CQFX@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMS3_k127_1128080_15	469383.Cwoe_4713	9.574e-31	124.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria	201174|Actinobacteria	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_1128080_6	1283299.AUKG01000001_gene2557	9.831e-71	260.0	2DKYN@1|root,30WXH@2|Bacteria,2HQHS@201174|Actinobacteria,4CS33@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS3_k127_1128080_13	102125.Xen7305DRAFT_00036350	5.745e-33	138.0	COG1020@1|root,COG1020@2|Bacteria,1G3S2@1117|Cyanobacteria,3VM13@52604|Pleurocapsales	1117|Cyanobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	Condensation,PP-binding,Thioesterase
MMS3_k127_1128080_9	469383.Cwoe_1589	6.646e-49	183.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_1128080_17	469383.Cwoe_4704	4.376e-25	109.0	COG0607@1|root,COG0607@2|Bacteria,2IQ2S@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS3_k127_1128080_1	1380390.JIAT01000009_gene500	1.433e-184	583.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CPP6@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_113543_17	929712.KI912613_gene3029	5.737e-51	190.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS3_k127_113543_6	219305.MCAG_05011	2.567e-173	561.0	COG1233@1|root,COG1233@2|Bacteria,2GP0A@201174|Actinobacteria,4DENF@85008|Micromonosporales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,FAD_binding_6,Fer2,NAD_binding_1
MMS3_k127_113543_22	215803.DB30_6611	1.055e-21	102.0	COG1695@1|root,COG1695@2|Bacteria,1RFWJ@1224|Proteobacteria,42W87@68525|delta/epsilon subdivisions,2WR6P@28221|Deltaproteobacteria,2YX8V@29|Myxococcales	28221|Deltaproteobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
MMS3_k127_113543_7	426114.THI_3114	8.593e-118	394.0	COG1024@1|root,COG1024@2|Bacteria,1MXEN@1224|Proteobacteria	1224|Proteobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS3_k127_113543_5	1101188.KI912155_gene1695	2.075e-179	581.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
MMS3_k127_113543_2	469383.Cwoe_5915	4.053e-224	701.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CPAP@84995|Rubrobacteria	84995|Rubrobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
MMS3_k127_113543_16	929712.KI912613_gene540	1.579e-52	195.0	COG1484@1|root,COG1484@2|Bacteria,2GNJG@201174|Actinobacteria,4CQKR@84995|Rubrobacteria	84995|Rubrobacteria	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
MMS3_k127_113543_3	469383.Cwoe_5914	1.485e-202	641.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CPNU@84995|Rubrobacteria	84995|Rubrobacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
MMS3_k127_113543_15	469383.Cwoe_5913	6.38e-56	205.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4CQHN@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
MMS3_k127_113543_20	1283299.AUKG01000001_gene1817	9.575e-41	153.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4CQW6@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
MMS3_k127_113543_13	469383.Cwoe_5911	2.79e-62	217.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CQAY@84995|Rubrobacteria	84995|Rubrobacteria	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
MMS3_k127_113543_10	469383.Cwoe_5323	3.773e-74	255.0	COG3000@1|root,COG3000@2|Bacteria,2ISSM@201174|Actinobacteria,4CQ11@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
MMS3_k127_113543_23	1380390.JIAT01000009_gene1857	1.003e-16	88.0	COG0360@1|root,COG0360@2|Bacteria,2HPGC@201174|Actinobacteria,4CQUW@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S6	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
MMS3_k127_113543_0	469383.Cwoe_5909	1.707e-261	813.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4CPJV@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl transferase, family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
MMS3_k127_113543_1	1380390.JIAT01000009_gene1860	3.912e-225	703.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4CPFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
MMS3_k127_113543_8	469383.Cwoe_5904	6.871e-113	398.0	COG2234@1|root,COG2234@2|Bacteria,2HNS9@201174|Actinobacteria,4CPZX@84995|Rubrobacteria	84995|Rubrobacteria	S	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_113543_14	1380390.JIAT01000009_gene1865	6.707e-61	228.0	COG3764@1|root,COG3764@2|Bacteria,2HGXP@201174|Actinobacteria,4CRIX@84995|Rubrobacteria	84995|Rubrobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
MMS3_k127_113543_12	469383.Cwoe_5901	1.142e-69	250.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4CQGK@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_113543_21	469383.Cwoe_5900	8.548e-36	136.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4CQCQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
MMS3_k127_113543_4	469383.Cwoe_5899	6.586e-184	598.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
MMS3_k127_113543_9	469383.Cwoe_5897	2.649e-92	336.0	COG5542@1|root,COG5542@2|Bacteria,2HNS4@201174|Actinobacteria,4CPZM@84995|Rubrobacteria	84995|Rubrobacteria	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
MMS3_k127_113543_18	469383.Cwoe_5895	7.509e-51	190.0	COG1266@1|root,COG1266@2|Bacteria,2HRHJ@201174|Actinobacteria,4CTHE@84995|Rubrobacteria	84995|Rubrobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_113543_11	1283299.AUKG01000001_gene1838	2.835e-73	281.0	COG1376@1|root,COG1376@2|Bacteria,2HNPR@201174|Actinobacteria,4CPVE@84995|Rubrobacteria	84995|Rubrobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
MMS3_k127_113543_24	1283299.AUKG01000001_gene1841	5.48e-08	59.0	2AWSW@1|root,31NPW@2|Bacteria,2HR8R@201174|Actinobacteria,4CT52@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_113543_19	469383.Cwoe_5893	3.201e-47	175.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,4CPYW@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
MMS3_k127_1136357_5	1380390.JIAT01000010_gene3615	3.591e-82	280.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4CR9J@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_1136357_2	929712.KI912613_gene1819	5.339e-136	443.0	COG0393@1|root,COG0393@2|Bacteria,2I9NA@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
MMS3_k127_1136357_7	929712.KI912613_gene1820	2.465e-40	161.0	COG0393@1|root,COG0393@2|Bacteria,2I9NA@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
MMS3_k127_1136357_3	1380390.JIAT01000010_gene3616	3.87e-135	437.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
MMS3_k127_1136357_0	867903.ThesuDRAFT_01485	1.04e-203	648.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,24BNG@186801|Clostridia,3WD5E@538999|Clostridiales incertae sedis	186801|Clostridia	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
MMS3_k127_1136357_1	931627.MycrhDRAFT_5190	3.454e-149	487.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,2369H@1762|Mycobacteriaceae	201174|Actinobacteria	J	Belongs to the amidase family	amiB2	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS3_k127_1136357_4	469383.Cwoe_4057	1.525e-82	297.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria,4CT0C@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
MMS3_k127_1136357_6	1283299.AUKG01000002_gene4418	3.617e-54	195.0	2B40Q@1|root,31WQZ@2|Bacteria,2HY8X@201174|Actinobacteria,4CQG9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1136357_11	1116232.AHBF01000125_gene9441	0.000227	53.0	COG4733@1|root,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14
MMS3_k127_1142617_18	1120950.KB892761_gene5806	1.559e-06	53.0	COG1396@1|root,COG1396@2|Bacteria,2I2QT@201174|Actinobacteria	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
MMS3_k127_1142617_3	469383.Cwoe_1846	2.499e-173	553.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CPXX@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_1142617_16	1283299.AUKG01000001_gene3152	3.223e-27	121.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4CQGR@84995|Rubrobacteria	84995|Rubrobacteria	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
MMS3_k127_1142617_14	1283299.AUKG01000001_gene3153	1.355e-34	136.0	2BCFA@1|root,3260X@2|Bacteria,2HBC1@201174|Actinobacteria,4CT3V@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
MMS3_k127_1142617_8	469383.Cwoe_1855	3.748e-97	321.0	COG4293@1|root,COG4293@2|Bacteria,2IG98@201174|Actinobacteria,4CQEX@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
MMS3_k127_1142617_0	469383.Cwoe_1856	1.435e-221	702.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_1142617_1	469383.Cwoe_1857	3.654e-216	690.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CPCB@84995|Rubrobacteria	84995|Rubrobacteria	EQ	Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_1142617_12	469383.Cwoe_1858	7.56e-47	173.0	2B6US@1|root,31ZU9@2|Bacteria,2HRE3@201174|Actinobacteria,4CTC7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1142617_2	469383.Cwoe_1859	4.649e-175	563.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4CPRT@84995|Rubrobacteria	84995|Rubrobacteria	H	Glucose inhibited division protein A	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_1142617_19	1380390.JIAT01000014_gene6106	5.126e-06	59.0	2A2FM@1|root,30QSR@2|Bacteria,2HRCN@201174|Actinobacteria,4CTA4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1142617_13	1283299.AUKG01000001_gene3178	7.784e-38	154.0	2A312@1|root,30RFU@2|Bacteria,2HP4M@201174|Actinobacteria,4CQG7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1142617_9	469383.Cwoe_1863	3.597e-93	316.0	COG0438@1|root,COG0438@2|Bacteria,2I8DC@201174|Actinobacteria,4CR51@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
MMS3_k127_1142617_5	1283299.AUKG01000001_gene3180	1.504e-112	370.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CQ0N@84995|Rubrobacteria	84995|Rubrobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
MMS3_k127_1142617_6	1283299.AUKG01000001_gene3181	4.602e-107	352.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CRUV@84995|Rubrobacteria	84995|Rubrobacteria	J	3' exoribonuclease family, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	RNase_PH,RNase_PH_C
MMS3_k127_1142617_11	469383.Cwoe_1867	7.281e-70	244.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CQ3I@84995|Rubrobacteria	84995|Rubrobacteria	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
MMS3_k127_1142617_15	1283299.AUKG01000001_gene3185	1.301e-31	126.0	COG0776@1|root,COG0776@2|Bacteria,2HRDQ@201174|Actinobacteria,4CTBM@84995|Rubrobacteria	84995|Rubrobacteria	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
MMS3_k127_1142617_7	1283299.AUKG01000001_gene3186	2.358e-101	338.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CQ00@84995|Rubrobacteria	84995|Rubrobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
MMS3_k127_1142617_4	1380390.JIAT01000014_gene6094	5.408e-140	451.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4CQ17@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_1142617_10	469383.Cwoe_5743	1.637e-76	267.0	COG1277@1|root,COG1277@2|Bacteria,2GR00@201174|Actinobacteria,4CQ7Z@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
MMS3_k127_1163329_3	1121946.AUAX01000018_gene6933	8.298e-194	616.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4D94H@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
MMS3_k127_1163329_5	591158.SSMG_05287	2.484e-145	469.0	COG1960@1|root,COG1960@2|Bacteria,2I8DF@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	ko:K04117	ko00362,ko01120,map00362,map01120	M00540	R05619	RC02035	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1163329_8	656024.FsymDg_2021	1.397e-122	398.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4ERHV@85013|Frankiales	201174|Actinobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_1163329_9	1206730.BAGA01000070_gene1577	8.227e-83	287.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4G8JY@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1163329_12	469383.Cwoe_3924	4.348e-60	229.0	COG1216@1|root,COG1216@2|Bacteria,2IIII@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1163329_10	1380390.JIAT01000014_gene6152	1.67e-75	262.0	2AW45@1|root,31MZ2@2|Bacteria,2HNU6@201174|Actinobacteria,4CQ2D@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1163329_2	1283299.AUKG01000001_gene3110	3.137e-232	752.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4CPKY@84995|Rubrobacteria	84995|Rubrobacteria	E	NADH NADPH, small subunit	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
MMS3_k127_1163329_0	1303518.CCALI_01654	0.0	1738.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria	2|Bacteria	E	L-glutamate biosynthetic process	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
MMS3_k127_1163329_4	469383.Cwoe_1805	2.265e-154	518.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4CPD7@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
MMS3_k127_1163329_11	1380390.JIAT01000014_gene6207	1.699e-70	252.0	COG3857@1|root,COG3857@2|Bacteria,2HNUC@201174|Actinobacteria,4CQ2I@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
MMS3_k127_1163329_1	469383.Cwoe_1803	0.0	1100.0	COG0550@1|root,COG0550@2|Bacteria,2GJU7@201174|Actinobacteria,4CPD0@84995|Rubrobacteria	84995|Rubrobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
MMS3_k127_1163329_7	1380390.JIAT01000011_gene2768	6.258e-125	406.0	COG0767@1|root,COG0767@2|Bacteria,2GJ27@201174|Actinobacteria,4CPTC@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
MMS3_k127_1163329_6	929712.KI912613_gene4841	1.557e-125	405.0	COG0767@1|root,COG0767@2|Bacteria,2IAUN@201174|Actinobacteria,4CR2S@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
MMS3_k127_1174562_8	1054860.KB913030_gene4066	5.473e-143	460.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMS3_k127_1174562_2	469383.Cwoe_0911	1.389e-225	706.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS3_k127_1174562_1	469383.Cwoe_5281	2.633e-230	726.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4CPIR@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
MMS3_k127_1174562_11	469383.Cwoe_5283	2.942e-95	325.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4CPHM@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
MMS3_k127_1174562_0	1380390.JIAT01000009_gene801	1.589e-286	887.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CP7M@84995|Rubrobacteria	84995|Rubrobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_1174562_3	1283299.AUKG01000003_gene514	4.118e-182	583.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CPGQ@84995|Rubrobacteria	84995|Rubrobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
MMS3_k127_1174562_6	469383.Cwoe_5286	1.26e-157	515.0	COG2048@1|root,COG2048@2|Bacteria,2H014@201174|Actinobacteria,4CPAS@84995|Rubrobacteria	84995|Rubrobacteria	C	Cysteine-rich domain	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
MMS3_k127_1174562_7	1283299.AUKG01000001_gene1811	2.731e-144	466.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4CPEJ@84995|Rubrobacteria	84995|Rubrobacteria	M	UDP-N-acetylglucosamine 2-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase_2
MMS3_k127_1174562_10	502025.Hoch_0307	1.728e-96	332.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2X9QV@28221|Deltaproteobacteria,2Z1C8@29|Myxococcales	28221|Deltaproteobacteria	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
MMS3_k127_1174562_15	469383.Cwoe_4717	2.87e-28	129.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4CQKG@84995|Rubrobacteria	84995|Rubrobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
MMS3_k127_1174562_16	929712.KI912613_gene20	8.017e-26	115.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria	201174|Actinobacteria	P	Divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
MMS3_k127_1174562_4	1380390.JIAT01000009_gene808	1.888e-179	571.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CPEZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
MMS3_k127_1174562_9	469383.Cwoe_5291	2.321e-97	326.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CQ0D@84995|Rubrobacteria	84995|Rubrobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
MMS3_k127_1174562_14	469383.Cwoe_5292	9.114e-30	125.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4CQFN@84995|Rubrobacteria	84995|Rubrobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
MMS3_k127_1174562_5	1283299.AUKG01000003_gene500	3.374e-173	567.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
MMS3_k127_1174562_12	1380390.JIAT01000009_gene815	4.483e-90	325.0	2AXGW@1|root,31PGJ@2|Bacteria,2HNNC@201174|Actinobacteria,4CPSP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1174562_13	1125971.ASJB01000051_gene5045	1.646e-36	147.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4E3SA@85010|Pseudonocardiales	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
MMS3_k127_1204705_3	469383.Cwoe_5251	2.716e-152	501.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CPJI@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
MMS3_k127_1204705_2	1283299.AUKG01000003_gene570	2.486e-174	559.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CPAI@84995|Rubrobacteria	84995|Rubrobacteria	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
MMS3_k127_1204705_9	1380390.JIAT01000009_gene727	1.885e-61	219.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CQ60@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
MMS3_k127_1204705_7	469383.Cwoe_5242	4.256e-68	239.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CQJ6@84995|Rubrobacteria	84995|Rubrobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
MMS3_k127_1204705_0	1380356.JNIK01000011_gene1622	4.976e-235	769.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4ERK2@85013|Frankiales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
MMS3_k127_1204705_5	1283299.AUKG01000003_gene583	1.458e-92	317.0	COG0760@1|root,COG0760@2|Bacteria,2IRIE@201174|Actinobacteria,4CQM6@84995|Rubrobacteria	84995|Rubrobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
MMS3_k127_1204705_1	1283299.AUKG01000003_gene585	2.956e-210	661.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CPAA@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMS3_k127_1204705_15	469383.Cwoe_5237	6.696e-17	85.0	COG2919@1|root,COG2919@2|Bacteria,2HRVE@201174|Actinobacteria,4CTYU@84995|Rubrobacteria	84995|Rubrobacteria	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
MMS3_k127_1204705_12	1283299.AUKG01000003_gene587	4.058e-33	131.0	2AUU5@1|root,31KH9@2|Bacteria,2HPC7@201174|Actinobacteria,4CQQB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1204705_8	469383.Cwoe_5235	1.35e-62	220.0	COG1278@1|root,COG1278@2|Bacteria,2HR26@201174|Actinobacteria,4CSWY@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock	-	-	-	-	-	-	-	-	-	-	-	-	CSD
MMS3_k127_1204705_13	469383.Cwoe_5234	5.188e-21	94.0	COG1551@1|root,COG1551@2|Bacteria,2GRPH@201174|Actinobacteria	201174|Actinobacteria	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
MMS3_k127_1204705_4	469383.Cwoe_5231	1.71e-137	445.0	COG3892@1|root,COG3892@2|Bacteria,2INPC@201174|Actinobacteria,4CRB8@84995|Rubrobacteria	84995|Rubrobacteria	G	Uncharacterized protein conserved in bacteria (DUF2090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2090
MMS3_k127_1204705_10	469383.Cwoe_5229	2.329e-48	184.0	2BHC2@1|root,32BDR@2|Bacteria,2HQHF@201174|Actinobacteria,4CS2N@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMS3_k127_1204705_6	469383.Cwoe_5227	8.107e-92	307.0	COG2220@1|root,COG2220@2|Bacteria,2HP2V@201174|Actinobacteria,4CQDX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
MMS3_k127_1204705_11	1380390.JIAT01000009_gene704	3.884e-35	139.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4CQQR@84995|Rubrobacteria	84995|Rubrobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
MMS3_k127_121184_7	356851.JOAN01000024_gene4513	1.031e-41	159.0	COG4221@1|root,COG4221@2|Bacteria,2I2DY@201174|Actinobacteria,4D8XM@85008|Micromonosporales	201174|Actinobacteria	S	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_121184_1	1079460.ATTQ01000010_gene140	6.566e-223	696.0	COG1052@1|root,COG1052@2|Bacteria,1PDP1@1224|Proteobacteria,2U0EU@28211|Alphaproteobacteria,4BBBN@82115|Rhizobiaceae	28211|Alphaproteobacteria	CH	Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms	fdh	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_121184_3	1283299.AUKG01000003_gene257	4.704e-126	412.0	COG0392@1|root,COG0392@2|Bacteria,2HNI1@201174|Actinobacteria,4CPH1@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
MMS3_k127_121184_8	469383.Cwoe_1137	7.86e-34	132.0	2A23K@1|root,30QDU@2|Bacteria,2HRA7@201174|Actinobacteria,4CT74@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_121184_9	1380390.JIAT01000009_gene1183	3.942e-33	139.0	2AUIS@1|root,31K7B@2|Bacteria,2HP5N@201174|Actinobacteria,4CQHP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_121184_0	469383.Cwoe_1140	0.0	1055.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CP6D@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS3_k127_121184_6	1089545.KB913037_gene7385	9.308e-43	163.0	COG3742@1|root,COG3742@2|Bacteria,2IS39@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K19686	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
MMS3_k127_121184_10	1122222.AXWR01000027_gene232	1.244e-18	88.0	COG4423@1|root,COG4423@2|Bacteria,1WKIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Rv0623-like transcription factor	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	PSK_trans_fac
MMS3_k127_121184_4	1283299.AUKG01000003_gene284	2.241e-119	391.0	COG1351@1|root,COG1351@2|Bacteria,2HCNJ@201174|Actinobacteria,4CQKC@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
MMS3_k127_121184_5	929712.KI912613_gene4233	9.589e-98	325.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_121184_2	469383.Cwoe_3715	3.171e-163	554.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1222481_17	1380390.JIAT01000009_gene1555	9.672e-63	221.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4CQ70@84995|Rubrobacteria	84995|Rubrobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
MMS3_k127_1222481_10	469383.Cwoe_0773	4.171e-116	387.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,4CQAU@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_1222481_23	1089453.GOSPT_133_00320	3.088e-09	64.0	COG2104@1|root,COG2104@2|Bacteria,2HXEB@201174|Actinobacteria,4GFGC@85026|Gordoniaceae	201174|Actinobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS3_k127_1222481_9	469383.Cwoe_0775	5.662e-118	393.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4CPZT@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
MMS3_k127_1222481_25	1380390.JIAT01000009_gene1547	8.507e-07	59.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,4CTF4@84995|Rubrobacteria	84995|Rubrobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
MMS3_k127_1222481_8	469383.Cwoe_0778	1.838e-119	390.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CPYJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMS3_k127_1222481_3	469383.Cwoe_0782	2.922e-175	577.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CRR6@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
MMS3_k127_1222481_24	1449347.JQLN01000007_gene1388	2.954e-07	62.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,2M414@2063|Kitasatospora	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1222481_26	1380354.JIAN01000008_gene3362	5.437e-05	56.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,Malectin,PKD
MMS3_k127_1222481_7	469383.Cwoe_0785	1.145e-137	443.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CRRX@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
MMS3_k127_1222481_12	469383.Cwoe_0788	2.368e-93	318.0	COG1573@1|root,COG1573@2|Bacteria,2HNTA@201174|Actinobacteria,4CQ1J@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
MMS3_k127_1222481_5	469383.Cwoe_0789	1.679e-157	518.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2HPUE@201174|Actinobacteria,4CR88@84995|Rubrobacteria	84995|Rubrobacteria	M	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
MMS3_k127_1222481_2	469383.Cwoe_0790	5.664e-207	650.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CQZJ@84995|Rubrobacteria	84995|Rubrobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
MMS3_k127_1222481_15	469383.Cwoe_0791	4.668e-79	280.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_1222481_16	469383.Cwoe_0792	1.362e-73	267.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4CRYZ@84995|Rubrobacteria	84995|Rubrobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
MMS3_k127_1222481_14	469383.Cwoe_0793	4.199e-88	317.0	COG1835@1|root,COG1835@2|Bacteria,2GMY0@201174|Actinobacteria,4CRDF@84995|Rubrobacteria	84995|Rubrobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1222481_13	1283299.AUKG01000001_gene1463	1.218e-89	312.0	COG0177@1|root,COG0177@2|Bacteria,2HPSY@201174|Actinobacteria,4CR6E@84995|Rubrobacteria	84995|Rubrobacteria	L	FES	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
MMS3_k127_1222481_11	1380390.JIAT01000017_gene5247	1.023e-115	383.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria,4CP9B@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
MMS3_k127_1222481_0	469383.Cwoe_0798	0.0	1077.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CP69@84995|Rubrobacteria	84995|Rubrobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
MMS3_k127_1222481_19	469383.Cwoe_0799	4.839e-49	181.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CQBV@84995|Rubrobacteria	84995|Rubrobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
MMS3_k127_1222481_6	469383.Cwoe_0800	8.648e-148	476.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CPEG@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS3_k127_1222481_21	469383.Cwoe_0801	8.221e-41	157.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CQCY@84995|Rubrobacteria	84995|Rubrobacteria	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
MMS3_k127_1222481_1	469383.Cwoe_0802	1.033e-321	1004.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CQYD@84995|Rubrobacteria	84995|Rubrobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS3_k127_1222481_20	1380390.JIAT01000009_gene1493	1.982e-43	162.0	COG4274@1|root,COG4274@2|Bacteria,2HR6Q@201174|Actinobacteria,4CT2K@84995|Rubrobacteria	84995|Rubrobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_1222481_4	469383.Cwoe_0807	7.742e-167	535.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CP95@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
MMS3_k127_1222481_18	469383.Cwoe_0808	9.997e-56	199.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CQ7C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
MMS3_k127_1222481_22	469383.Cwoe_0818	1.201e-11	67.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4CPI0@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
MMS3_k127_1250302_19	1380390.JIAT01000001_gene5024	8.229e-12	68.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CPKI@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
MMS3_k127_1250302_18	1380390.JIAT01000001_gene4995	2.676e-17	90.0	2AUSG@1|root,31KFH@2|Bacteria,2HPAB@201174|Actinobacteria,4CQNM@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1250302_16	1380390.JIAT01000009_gene1893	1.106e-26	126.0	COG0526@1|root,COG0526@2|Bacteria,2HP2C@201174|Actinobacteria,4CQDD@84995|Rubrobacteria	84995|Rubrobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
MMS3_k127_1250302_17	525904.Tter_0851	3.576e-19	102.0	COG1999@1|root,COG1999@2|Bacteria,2NQ63@2323|unclassified Bacteria	2|Bacteria	O	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	AhpC-TSA,SCO1-SenC
MMS3_k127_1250302_10	1380390.JIAT01000009_gene1204	3.486e-70	248.0	COG3336@1|root,COG3336@2|Bacteria,2HPY7@201174|Actinobacteria,4CRDE@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
MMS3_k127_1250302_0	469383.Cwoe_4536	1.309e-266	839.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CPMP@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
MMS3_k127_1250302_7	1380390.JIAT01000015_gene5677	4.578e-112	406.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CQY7@84995|Rubrobacteria	84995|Rubrobacteria	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_2
MMS3_k127_1250302_4	1380390.JIAT01000015_gene5679	1.939e-149	482.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CPFY@84995|Rubrobacteria	84995|Rubrobacteria	G	Glyceraldehyde-3-phosphate dehydrogenase, type I	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
MMS3_k127_1250302_5	469383.Cwoe_4529	1.677e-146	476.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CPN6@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
MMS3_k127_1250302_8	469383.Cwoe_4528	2.059e-110	377.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CQ0V@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
MMS3_k127_1250302_1	469383.Cwoe_4527	8.799e-203	657.0	COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CR8U@84995|Rubrobacteria	84995|Rubrobacteria	G	BPG-independent PGAM N-terminus (iPGM_N)	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
MMS3_k127_1250302_13	1380390.JIAT01000015_gene5685	8.917e-44	166.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4CQGU@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMS3_k127_1250302_14	525904.Tter_2070	1.335e-41	161.0	COG0586@1|root,COG0586@2|Bacteria,2NQ0I@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	dedA	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
MMS3_k127_1250302_3	469383.Cwoe_4524	3.05e-166	532.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CPB3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
MMS3_k127_1250302_6	469383.Cwoe_4523	9.295e-124	413.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CPGP@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMS3_k127_1250302_9	469383.Cwoe_4521	1.298e-102	341.0	COG0639@1|root,COG0639@2|Bacteria,2HNQI@201174|Actinobacteria,4CPX1@84995|Rubrobacteria	84995|Rubrobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_1250302_12	469383.Cwoe_4519	1.318e-46	170.0	2AZMM@1|root,31RWC@2|Bacteria,2HTXT@201174|Actinobacteria,4CT9J@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
MMS3_k127_1250302_2	469383.Cwoe_4517	2.029e-195	627.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CP8V@84995|Rubrobacteria	84995|Rubrobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
MMS3_k127_1250302_15	1380390.JIAT01000015_gene5704	1.543e-29	125.0	COG3088@1|root,COG3088@2|Bacteria,2GXH0@201174|Actinobacteria,4CT29@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
MMS3_k127_1250302_11	1380390.JIAT01000015_gene5705	4.771e-47	176.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4CQ9G@84995|Rubrobacteria	84995|Rubrobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMS3_k127_1255416_1	1242864.D187_002003	1.278e-37	146.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,433GE@68525|delta/epsilon subdivisions,2WYHA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Acetyltransferases including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_1255416_2	1123360.thalar_03292	4.247e-32	134.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
MMS3_k127_1255416_0	96561.Dole_0194	1.927e-259	831.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
MMS3_k127_1255416_3	439235.Dalk_1970	9.444e-20	90.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
MMS3_k127_1262824_1	1380390.JIAT01000009_gene2013	1.62e-148	486.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GISS@201174|Actinobacteria,4CPN9@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
MMS3_k127_1262824_3	469383.Cwoe_5822	2.957e-81	283.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4CT3X@84995|Rubrobacteria	84995|Rubrobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
MMS3_k127_1262824_0	1380390.JIAT01000009_gene2017	8.237e-173	551.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4CPSM@84995|Rubrobacteria	84995|Rubrobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
MMS3_k127_1262824_2	469383.Cwoe_1681	2.701e-135	464.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CR5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS3_k127_1262824_4	1304284.L21TH_0212	2.996e-61	218.0	COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae	186801|Clostridia	F	D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit	kamD	-	5.4.3.3	ko:K01844	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	Lys-AminoMut_A
MMS3_k127_1282828_6	469383.Cwoe_3528	2.991e-70	248.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CPKT@84995|Rubrobacteria	84995|Rubrobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMS3_k127_1282828_5	1380390.JIAT01000010_gene4518	1.991e-75	261.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CQ9Q@84995|Rubrobacteria	84995|Rubrobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMS3_k127_1282828_3	1283299.AUKG01000002_gene4909	6.525e-93	308.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CPW7@84995|Rubrobacteria	84995|Rubrobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
MMS3_k127_1282828_1	469383.Cwoe_3531	2.299e-130	432.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4CP7G@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
MMS3_k127_1282828_4	469383.Cwoe_3532	1.326e-89	302.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CPQH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
MMS3_k127_1282828_2	469383.Cwoe_3533	2.611e-118	389.0	COG3705@1|root,COG3705@2|Bacteria,2I6IJ@201174|Actinobacteria,4CQ6U@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidyl-tRNA synthetase	-	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
MMS3_k127_1282828_0	469383.Cwoe_3534	9.869e-201	635.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CPCY@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
MMS3_k127_1282828_10	1122921.KB898189_gene724	4.655e-07	57.0	2BR0X@1|root,32JYC@2|Bacteria,1U1R4@1239|Firmicutes,4IB7I@91061|Bacilli,273UA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1282828_7	1047013.AQSP01000121_gene2707	2.887e-51	183.0	2AU0F@1|root,31JKB@2|Bacteria,2NRBE@2323|unclassified Bacteria	2|Bacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1282828_9	1173021.ALWA01000034_gene4257	5.706e-12	67.0	2CW0Y@1|root,32SYT@2|Bacteria	2|Bacteria	S	the current gene model (or a revised gene model) may contain a premature stop	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1288645_2	1283299.AUKG01000002_gene4954	9.069e-89	301.0	COG0605@1|root,COG0605@2|Bacteria,2GJV8@201174|Actinobacteria,4CQ25@84995|Rubrobacteria	84995|Rubrobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
MMS3_k127_1288645_0	469383.Cwoe_3494	6.929e-167	538.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CS9W@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
MMS3_k127_1288645_3	469383.Cwoe_3493	6.761e-87	294.0	COG0558@1|root,COG0558@2|Bacteria,2HGA5@201174|Actinobacteria,4CR84@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_1288645_6	1283299.AUKG01000002_gene4958	2.184e-31	127.0	2AUU1@1|root,31KH5@2|Bacteria,2HPC3@201174|Actinobacteria,4CQQ6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1288645_5	469383.Cwoe_3491	3.105e-66	235.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4CQ8I@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
MMS3_k127_1288645_1	1283299.AUKG01000002_gene4960	1.515e-98	329.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4CPZY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
MMS3_k127_1288645_4	1380390.JIAT01000010_gene4571	3.418e-67	233.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CQ53@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
MMS3_k127_1288645_7	469383.Cwoe_3488	2.036e-21	100.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
MMS3_k127_1300271_5	1283299.AUKG01000001_gene1939	1.747e-161	535.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CP92@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
MMS3_k127_1300271_0	469383.Cwoe_5571	1.387e-320	1007.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4CPIU@84995|Rubrobacteria	84995|Rubrobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
MMS3_k127_1300271_19	469383.Cwoe_5332	4.274e-71	259.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,4CQ4N@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase family 2	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
MMS3_k127_1300271_15	469383.Cwoe_5567	1.358e-95	321.0	COG0561@1|root,COG0561@2|Bacteria,2HU8Y@201174|Actinobacteria,4CTUW@84995|Rubrobacteria	84995|Rubrobacteria	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1300271_24	1449080.JQMV01000006_gene2273	6.492e-13	72.0	COG5304@1|root,COG5304@2|Bacteria,1WKM9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
MMS3_k127_1300271_21	649638.Trad_1430	2.336e-21	97.0	2E3EN@1|root,32YDN@2|Bacteria,1WKIV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
MMS3_k127_1300271_23	195253.Syn6312_1997	1.336e-15	81.0	2E5P1@1|root,330DP@2|Bacteria,1G84E@1117|Cyanobacteria,1H1KP@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
MMS3_k127_1300271_10	1283299.AUKG01000001_gene2172	1.859e-134	447.0	COG0240@1|root,COG0240@2|Bacteria,2HYHZ@201174|Actinobacteria,4CQSG@84995|Rubrobacteria	84995|Rubrobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
MMS3_k127_1300271_16	419947.MRA_1786	1.254e-86	317.0	COG2234@1|root,COG2234@2|Bacteria,2I9S8@201174|Actinobacteria,237JC@1762|Mycobacteriaceae	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_1300271_22	469383.Cwoe_5564	3.047e-19	92.0	COG1929@1|root,COG1929@2|Bacteria	2|Bacteria	G	organic acid phosphorylation	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
MMS3_k127_1300271_11	469383.Cwoe_3833	4.589e-132	458.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4CS2X@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA primase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
MMS3_k127_1300271_12	469383.Cwoe_5554	1.986e-130	423.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4CR2R@84995|Rubrobacteria	84995|Rubrobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
MMS3_k127_1300271_13	1380390.JIAT01000009_gene2129	3.479e-112	366.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4CRF2@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
MMS3_k127_1300271_8	68170.KL590498_gene6665	1.095e-139	468.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4E0V6@85010|Pseudonocardiales	201174|Actinobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000,ko03000	-	-	-	Aminotran_1_2,GntR
MMS3_k127_1300271_9	1122939.ATUD01000011_gene2258	4.738e-139	458.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
MMS3_k127_1300271_4	929712.KI912613_gene1048	1.473e-186	595.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CPVD@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
MMS3_k127_1300271_14	469383.Cwoe_5542	3.078e-101	333.0	COG0637@1|root,COG0637@2|Bacteria,2I6IT@201174|Actinobacteria,4CRIS@84995|Rubrobacteria	84995|Rubrobacteria	S	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS3_k127_1300271_18	469383.Cwoe_5541	2.482e-71	252.0	COG0491@1|root,COG0491@2|Bacteria,2HPX6@201174|Actinobacteria,4CRW4@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_1300271_3	469383.Cwoe_5538	4.288e-283	883.0	COG0439@1|root,COG4770@1|root,COG0439@2|Bacteria,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
MMS3_k127_1300271_6	469383.Cwoe_5535	1.216e-160	511.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4CRG2@84995|Rubrobacteria	84995|Rubrobacteria	EH	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
MMS3_k127_1300271_17	1380390.JIAT01000009_gene2152	4.401e-83	284.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4CQ9K@84995|Rubrobacteria	84995|Rubrobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
MMS3_k127_1300271_2	469383.Cwoe_5531	5.587e-298	925.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
MMS3_k127_1300271_1	1380390.JIAT01000009_gene2164	5.267e-308	949.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CPHH@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMS3_k127_1300271_20	1283299.AUKG01000001_gene2225	2.948e-29	129.0	2AWNP@1|root,31NJG@2|Bacteria,2HR4I@201174|Actinobacteria,4CSZS@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1300271_7	469383.Cwoe_5289	3.209e-147	471.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CQ0I@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMS3_k127_1311814_40	1122939.ATUD01000003_gene3384	5.921e-23	101.0	COG2114@1|root,COG2114@2|Bacteria,2I900@201174|Actinobacteria,4CU3M@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
MMS3_k127_1311814_43	589924.Ferp_0438	4.379e-18	88.0	COG2361@1|root,arCOG05024@2157|Archaea,2Y6HF@28890|Euryarchaeota,246HB@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
MMS3_k127_1311814_36	882083.SacmaDRAFT_1891	4.822e-34	137.0	COG1396@1|root,COG1669@1|root,COG1396@2|Bacteria,COG1669@2|Bacteria,2HGH4@201174|Actinobacteria,4EDDK@85010|Pseudonocardiales	201174|Actinobacteria	K	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
MMS3_k127_1311814_25	1380390.JIAT01000009_gene980	3.966e-60	218.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4CRXR@84995|Rubrobacteria	84995|Rubrobacteria	P	Carbonic anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	Pro_CA
MMS3_k127_1311814_51	882082.SaccyDRAFT_1231	0.0008956	50.0	COG1309@1|root,COG1309@2|Bacteria,2IP2Y@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1311814_27	1121403.AUCV01000031_gene2838	7.048e-52	213.0	COG1361@1|root,COG3540@1|root,COG4733@1|root,COG1361@2|Bacteria,COG3540@2|Bacteria,COG4733@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA_membrane
MMS3_k127_1311814_6	469383.Cwoe_5342	8.346e-151	520.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1311814_46	1150864.MILUP08_44861	5.548e-13	78.0	2EDJR@1|root,337FI@2|Bacteria,2GIRI@201174|Actinobacteria,4DIZB@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1311814_45	1380390.JIAT01000003_gene5428	5.186e-13	74.0	2B6U0@1|root,31ZTD@2|Bacteria,2HRDT@201174|Actinobacteria,4CTBR@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1311814_23	298653.Franean1_6680	1.046e-61	233.0	COG2971@1|root,COG2971@2|Bacteria,2GKBF@201174|Actinobacteria,4ETJ8@85013|Frankiales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
MMS3_k127_1311814_16	525904.Tter_2402	5.056e-81	287.0	COG4833@1|root,COG4833@2|Bacteria	2|Bacteria	G	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_76
MMS3_k127_1311814_17	469383.Cwoe_2934	9.871e-80	286.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CPWX@84995|Rubrobacteria	84995|Rubrobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD_5
MMS3_k127_1311814_44	1492922.GY26_11115	8.049e-14	83.0	COG5607@1|root,COG5607@2|Bacteria,1Q6AS@1224|Proteobacteria,1T8T5@1236|Gammaproteobacteria,1JBGZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
MMS3_k127_1311814_42	1380390.JIAT01000015_gene5664	3.809e-20	104.0	2AX10@1|root,31NZ1@2|Bacteria,2HRFE@201174|Actinobacteria,4CTE5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1311814_38	656024.FsymDg_2398	5.454e-25	113.0	COG0515@1|root,COG0515@2|Bacteria,2I5IG@201174|Actinobacteria	201174|Actinobacteria	KLT	LppP/LprE lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_21
MMS3_k127_1311814_48	1121929.KB898664_gene1410	9.497e-09	59.0	COG5416@1|root,COG5416@2|Bacteria,1VGMG@1239|Firmicutes,4HQ29@91061|Bacilli,470Z5@74385|Gracilibacillus	91061|Bacilli	S	Pfam:DUF1049	yrvD	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
MMS3_k127_1311814_28	1380390.JIAT01000013_gene63	5.268e-50	187.0	COG0664@1|root,COG0664@2|Bacteria,2HPT0@201174|Actinobacteria,4CR6I@84995|Rubrobacteria	84995|Rubrobacteria	T	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
MMS3_k127_1311814_5	351607.Acel_0041	1.102e-198	638.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4EUUQ@85013|Frankiales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
MMS3_k127_1311814_31	2074.JNYD01000002_gene5467	1.161e-42	161.0	COG1846@1|root,COG1846@2|Bacteria,2IKZU@201174|Actinobacteria,4E50B@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMS3_k127_1311814_15	525909.Afer_0279	1.498e-81	276.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1311814_2	882083.SacmaDRAFT_2575	3.415e-307	962.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMS3_k127_1311814_19	1108045.GORHZ_135_00100	1.333e-77	267.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4GH00@85026|Gordoniaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
MMS3_k127_1311814_4	1108045.GORHZ_135_00090	1.455e-210	687.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
MMS3_k127_1311814_49	1463857.JOFZ01000006_gene3706	5.192e-07	61.0	2B277@1|root,31UQK@2|Bacteria,2GUAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1311814_35	266117.Rxyl_1827	2.979e-37	151.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
MMS3_k127_1311814_50	1227487.C474_02810	7.229e-05	55.0	COG0695@1|root,arCOG02608@2157|Archaea,2XYXV@28890|Euryarchaeota,23X05@183963|Halobacteria	183963|Halobacteria	O	COG0695 Glutaredoxin and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
MMS3_k127_1311814_3	1380390.JIAT01000009_gene649	1.294e-297	932.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_1311814_32	1380390.JIAT01000009_gene648	2.353e-41	154.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
MMS3_k127_1311814_26	1150864.MILUP08_42056	4.846e-56	203.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4DE1D@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_1311814_7	994479.GL877878_gene3047	2.443e-135	443.0	COG1752@1|root,COG1752@2|Bacteria,2IFBM@201174|Actinobacteria	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMS3_k127_1311814_14	1283299.AUKG01000002_gene4966	3.328e-85	301.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_1311814_10	1163408.UU9_07376	6.384e-108	365.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria,1X5H9@135614|Xanthomonadales	135614|Xanthomonadales	S	Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_13
MMS3_k127_1311814_47	1463917.JODC01000015_gene1752	5.121e-10	64.0	COG3905@1|root,COG3905@2|Bacteria,2GWKG@201174|Actinobacteria	201174|Actinobacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	vapB43	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944	-	-	-	-	-	-	-	-	-	-	RHH_1
MMS3_k127_1311814_30	870187.Thini_1711	9.227e-48	179.0	COG1848@1|root,COG1848@2|Bacteria,1N8VX@1224|Proteobacteria,1SP0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_1311814_8	469383.Cwoe_5367	2.033e-130	424.0	COG1469@1|root,COG1469@2|Bacteria,2IBX9@201174|Actinobacteria	201174|Actinobacteria	S	Type I GTP cyclohydrolase folE2	-	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
MMS3_k127_1311814_24	469383.Cwoe_5368	7.5e-61	217.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CQIK@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_1311814_34	1278073.MYSTI_02180	1.699e-39	164.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
MMS3_k127_1311814_12	469383.Cwoe_5374	2.45e-97	320.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CR9W@84995|Rubrobacteria	84995|Rubrobacteria	OU	Clp protease	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_1311814_37	469383.Cwoe_1320	2.958e-25	108.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4CQU8@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
MMS3_k127_1311814_39	1283299.AUKG01000001_gene2599	1.499e-23	108.0	COG0690@1|root,COG0690@2|Bacteria,2HQ1F@201174|Actinobacteria,4CRHK@84995|Rubrobacteria	84995|Rubrobacteria	U	SecE/Sec61-gamma subunits of protein translocation complex	-	-	-	-	-	-	-	-	-	-	-	-	SecE
MMS3_k127_1311814_13	469383.Cwoe_1322	2.447e-88	294.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CQ4I@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
MMS3_k127_1311814_22	1380390.JIAT01000011_gene2555	6.215e-67	229.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4CQ3Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
MMS3_k127_1311814_9	469383.Cwoe_1324	2.549e-119	389.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CPV5@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
MMS3_k127_1311814_21	1380390.JIAT01000011_gene2557	6.106e-69	243.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CQ0J@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
MMS3_k127_1311814_29	469383.Cwoe_1326	3.45e-48	175.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4CQ9X@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
MMS3_k127_1311814_1	469383.Cwoe_1327	0.0	2012.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CPMH@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
MMS3_k127_1311814_0	469383.Cwoe_1328	0.0	2224.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CP97@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMS3_k127_1311814_33	469383.Cwoe_1330	3.019e-41	162.0	29XHR@1|root,30J8F@2|Bacteria,2HU87@201174|Actinobacteria,4CTU4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1311814_11	469383.Cwoe_1331	3.251e-106	352.0	2AVXX@1|root,31MS0@2|Bacteria,2HQEJ@201174|Actinobacteria,4CRZD@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mg_trans_NIPA
MMS3_k127_1311814_20	469383.Cwoe_1335	2.199e-69	238.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4CQ35@84995|Rubrobacteria	84995|Rubrobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
MMS3_k127_1311814_18	469383.Cwoe_1336	1.205e-78	265.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4CQ77@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
MMS3_k127_1328350_6	469383.Cwoe_0998	2.901e-23	108.0	COG0596@1|root,COG0596@2|Bacteria,2GNK7@201174|Actinobacteria,4CQZK@84995|Rubrobacteria	84995|Rubrobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
MMS3_k127_1328350_1	469383.Cwoe_4232	5.485e-227	718.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
MMS3_k127_1328350_4	1122182.KB903833_gene5380	2.07e-29	130.0	2EDJR@1|root,337FI@2|Bacteria,2GIRI@201174|Actinobacteria,4DIZB@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1328350_0	1380390.JIAT01000010_gene3513	1.382e-269	833.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CP7E@84995|Rubrobacteria	84995|Rubrobacteria	E	glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
MMS3_k127_1328350_5	1380390.JIAT01000010_gene3509	6.636e-24	112.0	COG2010@1|root,COG2010@2|Bacteria,2HQZ9@201174|Actinobacteria,4CSSG@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMS3_k127_1328350_3	469383.Cwoe_5741	1.513e-50	194.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
MMS3_k127_1328350_2	469383.Cwoe_5742	2.009e-114	387.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4CU23@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1362234_1	469383.Cwoe_4871	5.607e-113	387.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1362234_2	1122939.ATUD01000013_gene920	9.466e-34	149.0	28K6W@1|root,2Z9V8@2|Bacteria,2GNHU@201174|Actinobacteria,4CSYY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1362234_3	1114922.CIFAM_10_01055	8.697e-06	50.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,1SGD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	ahdIC	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMS3_k127_1362234_0	469383.Cwoe_5792	0.0	1711.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4CPU9@84995|Rubrobacteria	84995|Rubrobacteria	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMS3_k127_1364500_3	469383.Cwoe_3526	1.913e-92	314.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
MMS3_k127_1364500_4	469383.Cwoe_0793	4.372e-86	314.0	COG1835@1|root,COG1835@2|Bacteria,2GMY0@201174|Actinobacteria,4CRDF@84995|Rubrobacteria	84995|Rubrobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1364500_5	1380390.JIAT01000014_gene6048	4.988e-30	132.0	COG0392@1|root,COG0392@2|Bacteria,2HQ3T@201174|Actinobacteria,4CRKA@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
MMS3_k127_1364500_2	469383.Cwoe_1564	8.128e-98	324.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CQ1Q@84995|Rubrobacteria	84995|Rubrobacteria	T	Response regulator receiver	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1364500_1	469383.Cwoe_1565	6.635e-113	390.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07653	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1364500_6	1227352.C173_24627	1.401e-09	63.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSN6@1239|Firmicutes,4HC7D@91061|Bacilli,26TQN@186822|Paenibacillaceae	91061|Bacilli	T	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
MMS3_k127_1364500_0	1380390.JIAT01000016_gene5643	5.867e-117	379.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CP62@84995|Rubrobacteria	84995|Rubrobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
MMS3_k127_1389169_8	743525.TSC_c04750	1.333e-09	68.0	COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1WKRH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	COGs COG3593 ATP-dependent endonuclease of the OLD family	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15
MMS3_k127_1389169_5	953739.SVEN_0849	1.106e-27	121.0	COG0454@1|root,COG0456@2|Bacteria,2IHRD@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	ypeA	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
MMS3_k127_1389169_1	929712.KI912613_gene1442	3.624e-230	728.0	COG1651@1|root,COG3004@1|root,COG1651@2|Bacteria,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4CPMJ@84995|Rubrobacteria	84995|Rubrobacteria	OP	Na+/H+ antiporter 1	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1,Thioredoxin_4
MMS3_k127_1389169_6	929712.KI912613_gene206	4.702e-19	90.0	COG3609@1|root,COG3609@2|Bacteria,2I6Q5@201174|Actinobacteria	201174|Actinobacteria	K	addiction module antidote protein, CC2985 family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1389169_4	1146883.BLASA_3528	4.875e-38	145.0	COG2337@1|root,COG2337@2|Bacteria,2ISBP@201174|Actinobacteria,4EWGR@85013|Frankiales	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	mazF3	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006355,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045927,GO:0045934,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
MMS3_k127_1389169_2	1380370.JIBA01000012_gene3439	6.15e-91	310.0	2CDI5@1|root,2Z7ZQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1389169_3	926560.KE387023_gene1738	2.312e-83	283.0	COG4122@1|root,COG4122@2|Bacteria,1WKHV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
MMS3_k127_1389169_7	935948.KE386494_gene358	1.362e-15	90.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
MMS3_k127_1389169_0	469383.Cwoe_2928	3.9e-239	745.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4CPRA@84995|Rubrobacteria	84995|Rubrobacteria	O	Lon protease (S16) C-terminal proteolytic domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMS3_k127_1430558_2	1283299.AUKG01000001_gene2027	1.248e-70	248.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4CPU9@84995|Rubrobacteria	84995|Rubrobacteria	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMS3_k127_1430558_4	1299327.I546_4012	3.565e-50	180.0	COG2337@1|root,COG2337@2|Bacteria,2IMGQ@201174|Actinobacteria,23B5D@1762|Mycobacteriaceae	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	mazF5	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
MMS3_k127_1430558_7	1108045.GORHZ_053_00430	6.961e-22	96.0	2FDS3@1|root,345T0@2|Bacteria,2GUMT@201174|Actinobacteria	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
MMS3_k127_1430558_10	1286631.X805_30430	2.082e-09	71.0	COG1309@1|root,COG1309@2|Bacteria,1RE7F@1224|Proteobacteria,2VSAW@28216|Betaproteobacteria,1KMSA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1430558_9	469383.Cwoe_3152	8.649e-16	92.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1430558_8	1380390.JIAT01000009_gene2044	7.994e-22	106.0	2B4XQ@1|root,31XQM@2|Bacteria,2HR11@201174|Actinobacteria,4CSV5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1430558_1	1380390.JIAT01000009_gene2041	2.031e-93	311.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CPNY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_1430558_5	469383.Cwoe_5809	4.809e-42	164.0	COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_1430558_3	1380390.JIAT01000009_gene2039	1.02e-61	215.0	COG2411@1|root,COG2411@2|Bacteria,2HNQQ@201174|Actinobacteria,4CPX9@84995|Rubrobacteria	84995|Rubrobacteria	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
MMS3_k127_1430558_6	443906.CMM_2568	6.099e-36	139.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4FP1U@85023|Microbacteriaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
MMS3_k127_1430558_0	469383.Cwoe_5812	2.431e-124	402.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CP8M@84995|Rubrobacteria	84995|Rubrobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMS3_k127_1439183_0	1172179.AUKV01000009_gene4525	9.749e-317	992.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,HAD,Hydrolase,Hydrolase_3
MMS3_k127_1439183_2	215803.DB30_6316	1.783e-163	526.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2YWVW@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
MMS3_k127_1439183_10	222534.KB893728_gene5427	6.839e-60	221.0	COG1105@1|root,COG1105@2|Bacteria,2HNT1@201174|Actinobacteria,4ETRG@85013|Frankiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_1439183_14	929712.KI912613_gene2552	1.603e-34	141.0	COG4464@1|root,COG4464@2|Bacteria,2H0WF@201174|Actinobacteria,4CSZY@84995|Rubrobacteria	84995|Rubrobacteria	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
MMS3_k127_1439183_13	765420.OSCT_1742	4.884e-38	158.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1439183_12	1030157.AFMP01000009_gene3633	9.402e-57	206.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,2K9AK@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1439183_11	1041522.MCOL_V206215	1.409e-59	226.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GM3U@201174|Actinobacteria,23637@1762|Mycobacteriaceae	201174|Actinobacteria	S	AAA domain	-	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
MMS3_k127_1439183_15	1283299.AUKG01000006_gene759	4.72e-30	124.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1439183_3	1283299.AUKG01000001_gene2404	7.149e-145	478.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4CRWF@84995|Rubrobacteria	84995|Rubrobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
MMS3_k127_1439183_7	1380390.JIAT01000010_gene3918	4.599e-83	294.0	COG0446@1|root,COG0446@2|Bacteria,2HQQT@201174|Actinobacteria,4CSDR@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_1439183_9	1157943.KB892706_gene4128	1.444e-71	249.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,235ZG@1762|Mycobacteriaceae	201174|Actinobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMS3_k127_1439183_6	469383.Cwoe_0200	1.382e-94	336.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4CRBY@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
MMS3_k127_1439183_4	469383.Cwoe_0201	1.054e-109	362.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4CR0C@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
MMS3_k127_1439183_1	469383.Cwoe_4509	7.321e-201	651.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,4CQYU@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_1439183_8	685727.REQ_11640	2.603e-74	269.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4FU16@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1439183_5	469383.Cwoe_1565	1.099e-100	345.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07653	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1469507_4	1033739.CAEU01000109_gene872	2.259e-05	49.0	2DRWY@1|root,33DG4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1469507_0	469383.Cwoe_0846	2.533e-166	539.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CR3U@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_1469507_1	469383.Cwoe_4240	4.52e-160	518.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CSBR@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_1469507_2	345341.KUTG_00874	1.489e-30	135.0	COG5421@1|root,COG5421@2|Bacteria,2IEYR@201174|Actinobacteria	201174|Actinobacteria	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
MMS3_k127_1554036_25	479433.Caci_5166	2.926e-09	70.0	COG3534@1|root,COG4733@1|root,COG3534@2|Bacteria,COG4733@2|Bacteria,2GJIN@201174|Actinobacteria	201174|Actinobacteria	G	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_79C,RicinB_lectin_2
MMS3_k127_1554036_2	929712.KI912613_gene2910	6.665e-222	707.0	COG1164@1|root,COG1164@2|Bacteria,2IGPX@201174|Actinobacteria,4CPUP@84995|Rubrobacteria	84995|Rubrobacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
MMS3_k127_1554036_23	1120959.ATXF01000005_gene1021	3.374e-16	85.0	COG1848@1|root,COG1848@2|Bacteria,2IIF6@201174|Actinobacteria,4FSTD@85023|Microbacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_1554036_26	1385521.N803_10965	2.063e-06	53.0	COG2002@1|root,COG2002@2|Bacteria,2HANT@201174|Actinobacteria	201174|Actinobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1554036_5	1380390.JIAT01000009_gene1156	1.187e-184	616.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CPJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMS3_k127_1554036_6	469383.Cwoe_1161	2.746e-181	585.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4CQ12@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMS3_k127_1554036_0	469383.Cwoe_1160	6.584e-292	915.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4CPCM@84995|Rubrobacteria	84995|Rubrobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
MMS3_k127_1554036_18	1283299.AUKG01000003_gene295	2.299e-46	168.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CQIE@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMS3_k127_1554036_16	1380390.JIAT01000009_gene1152	5.313e-63	225.0	COG0839@1|root,COG0839@2|Bacteria,2HNU5@201174|Actinobacteria,4CQ2B@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q3
MMS3_k127_1554036_11	469383.Cwoe_1157	1.784e-91	320.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4CQRQ@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
MMS3_k127_1554036_7	1380390.JIAT01000009_gene1150	2.313e-156	530.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4CQ5K@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
MMS3_k127_1554036_1	469383.Cwoe_1155	1.146e-273	857.0	COG1034@1|root,COG1153@1|root,COG1034@2|Bacteria,COG1153@2|Bacteria,2GJGX@201174|Actinobacteria,4CR3F@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMS3_k127_1554036_3	469383.Cwoe_1154	4.601e-211	673.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4CR2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMS3_k127_1554036_14	1283299.AUKG01000003_gene301	1.661e-68	237.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4CP9Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMS3_k127_1554036_4	1380390.JIAT01000009_gene1146	9.764e-203	645.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CP64@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
MMS3_k127_1554036_15	469383.Cwoe_1151	2.463e-68	237.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CQ8D@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
MMS3_k127_1554036_12	1283299.AUKG01000003_gene304	1.227e-87	301.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4CPGB@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMS3_k127_1554036_19	1283299.AUKG01000003_gene305	3.247e-46	169.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4CQ6Q@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
MMS3_k127_1554036_22	1380390.JIAT01000009_gene1142	4.659e-26	115.0	2BGA2@1|root,32A7H@2|Bacteria,2HTT4@201174|Actinobacteria,4CT2Y@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1554036_21	469383.Cwoe_1146	3.758e-30	132.0	COG2010@1|root,COG2010@2|Bacteria,2HQT0@201174|Actinobacteria,4CSHK@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
MMS3_k127_1554036_8	469383.Cwoe_1145	2.554e-148	484.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CPM3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
MMS3_k127_1554036_24	1122604.JONR01000013_gene3289	1.75e-09	70.0	COG1309@1|root,COG1309@2|Bacteria,1RE7F@1224|Proteobacteria,1STEW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1554036_17	645465.ACUR01000205_gene573	1.892e-56	224.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Peptidase_M6
MMS3_k127_1554036_20	469383.Cwoe_3929	1.551e-43	172.0	2DSVT@1|root,33HM2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
MMS3_k127_1554036_13	469383.Cwoe_2588	1.574e-76	292.0	2DM58@1|root,31S4C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1554036_9	469383.Cwoe_2589	5.914e-114	406.0	COG1971@1|root,COG1971@2|Bacteria,2GUWT@201174|Actinobacteria,4CTGK@84995|Rubrobacteria	84995|Rubrobacteria	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1554036_10	469383.Cwoe_1333	9.108e-96	326.0	COG2508@1|root,COG2508@2|Bacteria,2GNDH@201174|Actinobacteria,4CRKT@84995|Rubrobacteria	84995|Rubrobacteria	QT	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
MMS3_k127_1567160_6	1283299.AUKG01000004_gene1197	1.711e-28	121.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CPNJ@84995|Rubrobacteria	84995|Rubrobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
MMS3_k127_1567160_2	1380390.JIAT01000016_gene5616	2.082e-82	282.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4CQAR@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
MMS3_k127_1567160_3	1283299.AUKG01000003_gene486	1.525e-55	209.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4CSK5@84995|Rubrobacteria	84995|Rubrobacteria	P	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1567160_1	1122939.ATUD01000002_gene1436	3.997e-112	376.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CPY3@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
MMS3_k127_1567160_4	1380390.JIAT01000016_gene5626	3.892e-38	150.0	COG0319@1|root,COG0319@2|Bacteria,2HN3K@201174|Actinobacteria,4CQHV@84995|Rubrobacteria	84995|Rubrobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
MMS3_k127_1567160_0	1380390.JIAT01000016_gene5627	2.986e-162	518.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CPBK@84995|Rubrobacteria	84995|Rubrobacteria	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
MMS3_k127_1567160_5	469383.Cwoe_2848	7.583e-38	152.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,4CQJX@84995|Rubrobacteria	84995|Rubrobacteria	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
MMS3_k127_1567160_7	266117.Rxyl_1073	7.434e-06	53.0	COG2159@1|root,COG2159@2|Bacteria,2HJ7X@201174|Actinobacteria,4CPK2@84995|Rubrobacteria	84995|Rubrobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS3_k127_1607950_8	469383.Cwoe_0081	1.625e-07	56.0	COG1968@1|root,COG1968@2|Bacteria,2HNYX@201174|Actinobacteria,4CTDI@84995|Rubrobacteria	84995|Rubrobacteria	V	Bacitracin resistance protein BacA	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
MMS3_k127_1607950_2	1122939.ATUD01000013_gene869	3.02e-145	479.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMS3_k127_1607950_4	1380390.JIAT01000009_gene1775	7e-105	353.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CPG5@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
MMS3_k127_1607950_0	1380390.JIAT01000009_gene1776	3.433e-161	529.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
MMS3_k127_1607950_1	1380390.JIAT01000009_gene1777	4.081e-157	509.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CP9M@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
MMS3_k127_1607950_3	469383.Cwoe_0014	9.081e-107	372.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
MMS3_k127_1607950_7	1380390.JIAT01000009_gene1780	1.173e-56	209.0	COG1716@1|root,COG1716@2|Bacteria,2HM1E@201174|Actinobacteria,4CQ7B@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMS3_k127_1607950_6	1380390.JIAT01000009_gene1781	5.347e-91	307.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CQB6@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
MMS3_k127_1607950_5	469383.Cwoe_0011	4.926e-95	332.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CR9T@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
MMS3_k127_1610625_1	469383.Cwoe_3663	1.457e-90	302.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4CRH7@84995|Rubrobacteria	84995|Rubrobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
MMS3_k127_1610625_5	1184609.KILIM_001_00420	0.0005263	53.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4F7CZ@85018|Dermatophilaceae	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
MMS3_k127_1610625_3	765952.PUV_18860	2.965e-63	246.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF285,PKD
MMS3_k127_1610625_0	469383.Cwoe_2836	3.66e-189	610.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CQCB@84995|Rubrobacteria	84995|Rubrobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMS3_k127_1610625_4	469383.Cwoe_2835	9.766e-29	117.0	COG0268@1|root,COG0268@2|Bacteria,2HRKP@201174|Actinobacteria,4CTNG@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S20	-	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
MMS3_k127_1610625_2	469383.Cwoe_2834	1.47e-90	308.0	COG1466@1|root,COG1466@2|Bacteria,2HNE7@201174|Actinobacteria,4CP84@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
MMS3_k127_1622704_8	1380390.JIAT01000011_gene2629	3.948e-17	95.0	COG3291@1|root,COG3291@2|Bacteria,2I9UB@201174|Actinobacteria,4CTSN@84995|Rubrobacteria	84995|Rubrobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
MMS3_k127_1622704_6	1283299.AUKG01000003_gene391	8.261e-21	96.0	2B5N1@1|root,31YH9@2|Bacteria,2HR5Y@201174|Actinobacteria,4CT1J@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1622704_2	383372.Rcas_1513	1.409e-107	359.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi,3762T@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
MMS3_k127_1622704_7	1294142.CINTURNW_0526	8.628e-21	98.0	COG2246@1|root,COG2246@2|Bacteria,1VFGI@1239|Firmicutes,24RJP@186801|Clostridia	186801|Clostridia	S	PFAM GtrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
MMS3_k127_1622704_5	317936.Nos7107_0193	1.518e-52	196.0	COG0500@1|root,COG0500@2|Bacteria,1G9SQ@1117|Cyanobacteria,1HR4H@1161|Nostocales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMS3_k127_1622704_4	469383.Cwoe_4172	7.039e-79	269.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2GK7P@201174|Actinobacteria,4CQ80@84995|Rubrobacteria	84995|Rubrobacteria	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
MMS3_k127_1622704_1	469383.Cwoe_4171	8.292e-145	494.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4CPRN@84995|Rubrobacteria	84995|Rubrobacteria	P	Natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
MMS3_k127_1622704_9	1380390.JIAT01000010_gene4255	0.0003625	53.0	2AV79@1|root,31KXW@2|Bacteria,2HPNP@201174|Actinobacteria,4CR12@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1622704_3	1380393.JHVP01000005_gene3675	5.179e-87	304.0	COG0580@1|root,COG0580@2|Bacteria,2IG6C@201174|Actinobacteria,4ESCH@85013|Frankiales	201174|Actinobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
MMS3_k127_1622704_0	1380370.JIBA01000013_gene1327	7.806e-179	578.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4FG51@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
MMS3_k127_162274_18	1283299.AUKG01000002_gene4049	8.97e-79	276.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,4CPSR@84995|Rubrobacteria	84995|Rubrobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS3_k127_162274_20	1283299.AUKG01000002_gene4048	3.465e-70	248.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CQ28@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS3_k127_162274_13	1380393.JHVP01000002_gene2002	4.022e-97	328.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4ERC8@85013|Frankiales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMS3_k127_162274_10	1283299.AUKG01000002_gene4069	4.825e-105	347.0	COG0704@1|root,COG0704@2|Bacteria,2HGEG@201174|Actinobacteria,4CPTJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
MMS3_k127_162274_8	1380390.JIAT01000001_gene4996	1.925e-115	379.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CPSW@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_162274_26	322710.Avin_29020	3.047e-06	55.0	COG2062@1|root,COG2062@2|Bacteria,1NAAE@1224|Proteobacteria,1SD0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	phosphohistidine phosphatase	sixA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
MMS3_k127_162274_3	1183438.GKIL_2776	3.408e-216	692.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
MMS3_k127_162274_24	649638.Trad_2723	3.945e-48	185.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
MMS3_k127_162274_22	1283299.AUKG01000002_gene3714	6.747e-57	204.0	COG1225@1|root,COG1225@2|Bacteria,2IJVV@201174|Actinobacteria,4CRY9@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMS3_k127_162274_7	1267535.KB906767_gene5499	1.323e-126	423.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863,PQQ_2,PQQ_3
MMS3_k127_162274_4	298653.Franean1_5721	6.219e-186	611.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EUE1@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.6	-	-	MMPL
MMS3_k127_162274_12	469383.Cwoe_5454	5.781e-98	351.0	COG3119@1|root,COG3119@2|Bacteria,2HRVJ@201174|Actinobacteria,4CTZ0@84995|Rubrobacteria	84995|Rubrobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_162274_25	469383.Cwoe_4742	9.833e-39	160.0	COG0735@1|root,COG0735@2|Bacteria,2HTHG@201174|Actinobacteria,4CSV2@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMS3_k127_162274_19	1306990.BARG01000083_gene8385	6.3e-71	263.0	COG1108@1|root,COG1108@2|Bacteria	2|Bacteria	P	ABC-type Mn2 Zn2 transport systems permease components	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
MMS3_k127_162274_16	656024.FsymDg_3392	1.059e-87	299.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4ESS7@85013|Frankiales	201174|Actinobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
MMS3_k127_162274_11	479433.Caci_3196	1.214e-99	333.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K02074	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
MMS3_k127_162274_17	351607.Acel_2086	3.364e-83	293.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4ESYH@85013|Frankiales	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
MMS3_k127_162274_2	1380390.JIAT01000013_gene158	1.167e-231	724.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4CPKD@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
MMS3_k127_162274_1	469383.Cwoe_2006	4.423e-283	884.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_162274_6	118163.Ple7327_2930	2.088e-139	463.0	COG4992@1|root,COG4992@2|Bacteria,1G4MC@1117|Cyanobacteria,3VMJX@52604|Pleurocapsales	1117|Cyanobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_162274_5	1283299.AUKG01000001_gene2683	7.712e-165	535.0	COG1752@1|root,COG1752@2|Bacteria,2HPRW@201174|Actinobacteria,4CR58@84995|Rubrobacteria	84995|Rubrobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
MMS3_k127_162274_15	469383.Cwoe_1384	3.469e-88	309.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CQ4E@84995|Rubrobacteria	84995|Rubrobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
MMS3_k127_162274_0	1380390.JIAT01000011_gene2623	2.762e-308	957.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CPFU@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMS3_k127_162274_9	1380390.JIAT01000011_gene2622	2.764e-108	359.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4CQ4H@84995|Rubrobacteria	84995|Rubrobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
MMS3_k127_162274_14	1380390.JIAT01000011_gene2620	5.179e-95	320.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CQ1A@84995|Rubrobacteria	84995|Rubrobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
MMS3_k127_162274_23	1283299.AUKG01000001_gene2659	4.43e-55	196.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4CQ5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
MMS3_k127_162274_21	1283299.AUKG01000001_gene2658	1.883e-59	208.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CPU6@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
MMS3_k127_1707931_6	469383.Cwoe_5490	6.422e-51	186.0	COG0438@1|root,COG0438@2|Bacteria,2HPKT@201174|Actinobacteria,4CQYC@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1707931_1	469383.Cwoe_5496	3.846e-112	376.0	COG0438@1|root,COG0438@2|Bacteria,2GK9J@201174|Actinobacteria,4CS70@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1707931_4	1122939.ATUD01000006_gene1683	4.504e-77	271.0	COG0438@1|root,COG0438@2|Bacteria,2GK9J@201174|Actinobacteria,4CS70@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_1707931_3	98439.AJLL01000028_gene4258	1.422e-88	304.0	2DNEI@1|root,32X43@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1707931_5	1283299.AUKG01000001_gene2267	1.316e-69	257.0	COG2244@1|root,COG2244@2|Bacteria,2HR10@201174|Actinobacteria,4CSV4@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
MMS3_k127_1707931_10	1068980.ARVW01000001_gene3061	8.979e-17	94.0	COG0438@1|root,COG1216@1|root,COG2227@1|root,COG3064@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,COG3064@2|Bacteria,2HEKF@201174|Actinobacteria,4E1MZ@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_31
MMS3_k127_1707931_9	1395513.P343_09495	4.24e-23	108.0	2BNUI@1|root,32HIC@2|Bacteria,1V9B7@1239|Firmicutes,4HW4Y@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Nucleotid_trans
MMS3_k127_1707931_2	1283299.AUKG01000001_gene2265	2.086e-104	355.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.14,2.4.1.250	ko:K00696,ko:K15521	ko00500,ko01100,map00500,map01100	-	R00766	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,HEAT_2
MMS3_k127_1707931_8	1172188.KB911825_gene3539	1.647e-46	179.0	2F8QP@1|root,3412Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1707931_11	1121468.AUBR01000038_gene1959	2.394e-14	81.0	COG1848@1|root,COG1848@2|Bacteria,1V5H5@1239|Firmicutes,24HS5@186801|Clostridia,42GFS@68295|Thermoanaerobacterales	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_1707931_12	1184609.KILIM_033_00510	2.863e-08	58.0	COG4118@1|root,COG4118@2|Bacteria,2GQNI@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
MMS3_k127_1707931_0	656024.FsymDg_4517	7.439e-156	501.0	COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria	201174|Actinobacteria	J	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS3_k127_1707931_7	1160718.SU9_29356	4.265e-49	184.0	COG0524@1|root,COG0524@2|Bacteria,2H514@201174|Actinobacteria	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_1788729_30	1283299.AUKG01000002_gene4681	2.046e-31	139.0	2AX3W@1|root,31P29@2|Bacteria,2HRI6@201174|Actinobacteria,4CTIK@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1788729_27	929712.KI912613_gene1433	7.061e-38	160.0	COG1595@1|root,COG1595@2|Bacteria,2ICFT@201174|Actinobacteria,4CT38@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1788729_19	226899.F0XKG8	9.93e-74	265.0	COG0800@1|root,2RYBC@2759|Eukaryota,3A200@33154|Opisthokonta,3P2VX@4751|Fungi,3QVY6@4890|Ascomycota,21RWP@147550|Sordariomycetes	4751|Fungi	G	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_1788729_5	882083.SacmaDRAFT_2472	5.81e-128	421.0	COG0657@1|root,COG0657@2|Bacteria,2I6Z1@201174|Actinobacteria,4E5IP@85010|Pseudonocardiales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMS3_k127_1788729_21	1380390.JIAT01000009_gene358	3.787e-65	237.0	COG0208@1|root,COG0208@2|Bacteria,2GK48@201174|Actinobacteria,4CRR0@84995|Rubrobacteria	84995|Rubrobacteria	F	Ribonucleotide reductase, small chain	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_red_sm
MMS3_k127_1788729_23	469383.Cwoe_0590	1.387e-61	213.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4CQTZ@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
MMS3_k127_1788729_13	1283299.AUKG01000001_gene1395	5.282e-91	305.0	COG0580@1|root,COG0580@2|Bacteria,2GMG4@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	MIP
MMS3_k127_1788729_29	377629.TERTU_1239	4.779e-32	131.0	COG3791@1|root,COG3791@2|Bacteria,1N3P3@1224|Proteobacteria,1S57G@1236|Gammaproteobacteria,2PPWC@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
MMS3_k127_1788729_34	1121946.AUAX01000014_gene1110	6.961e-07	61.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4DCQV@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1788729_31	469383.Cwoe_3166	6.367e-21	107.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1788729_32	469383.Cwoe_3153	3.461e-18	98.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1788729_20	1122939.ATUD01000001_gene196	3.687e-71	253.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria	201174|Actinobacteria	I	phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
MMS3_k127_1788729_6	469383.Cwoe_4731	9.601e-125	436.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1788729_22	253839.SSNG_03476	1.929e-64	228.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1788729_25	469383.Cwoe_4730	7.611e-49	187.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1788729_33	288705.RSal33209_0622	1.699e-11	73.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,1WAK3@1268|Micrococcaceae	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
MMS3_k127_1788729_24	512565.AMIS_56130	2.106e-50	190.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4DD8B@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
MMS3_k127_1788729_18	469383.Cwoe_0795	3.755e-75	263.0	COG0596@1|root,COG0596@2|Bacteria,2HTV2@201174|Actinobacteria,4CTBC@84995|Rubrobacteria	84995|Rubrobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_1788729_14	679197.HMPREF9336_02445	2.486e-90	319.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria	201174|Actinobacteria	Q	beta-lactamase domain protein	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
MMS3_k127_1788729_16	446466.Cfla_0336	8.73e-86	290.0	COG0500@1|root,COG2226@2|Bacteria,2I3BB@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_1788729_15	469383.Cwoe_1070	2.843e-89	305.0	KOG2524@1|root,2ZJ84@2|Bacteria	2|Bacteria	S	Potential Queuosine, Q, salvage protein family	-	-	-	-	-	-	-	-	-	-	-	-	Q_salvage
MMS3_k127_1788729_2	216594.MMAR_2579	6.101e-169	541.0	COG0531@1|root,COG0531@2|Bacteria,2IDWU@201174|Actinobacteria,238HU@1762|Mycobacteriaceae	201174|Actinobacteria	E	thought to be involved in transport amino acids across the membrane	potE	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_1788729_1	1283299.AUKG01000002_gene3973	6.193e-198	624.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CPSQ@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1788729_9	1283299.AUKG01000002_gene3974	1.287e-101	340.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4CRTX@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
MMS3_k127_1788729_12	469383.Cwoe_1982	1.453e-96	326.0	COG1454@1|root,COG1454@2|Bacteria	2|Bacteria	C	hydroxyacid-oxoacid transhydrogenase activity	-	-	1.1.1.1	ko:K00001,ko:K13954,ko:K19954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
MMS3_k127_1788729_11	935548.KI912159_gene3192	5.476e-100	331.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2TUY3@28211|Alphaproteobacteria,43JIA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_1788729_7	469383.Cwoe_1557	5.386e-109	362.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4CT0Z@84995|Rubrobacteria	84995|Rubrobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_1788729_3	1133849.O3I_004050	3.543e-153	497.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4FVPA@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_1788729_17	469383.Cwoe_1284	8.406e-78	268.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria	201174|Actinobacteria	K	histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
MMS3_k127_1788729_26	1283299.AUKG01000001_gene3125	1.834e-44	163.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CQHE@84995|Rubrobacteria	84995|Rubrobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
MMS3_k127_1788729_0	469383.Cwoe_1834	9.135e-204	643.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CPIV@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_1788729_4	469383.Cwoe_1837	2.686e-142	476.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CPHC@84995|Rubrobacteria	84995|Rubrobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS3_k127_1788729_8	469383.Cwoe_1838	1.032e-108	364.0	COG0420@1|root,COG0420@2|Bacteria,2HPX3@201174|Actinobacteria,4CRBR@84995|Rubrobacteria	84995|Rubrobacteria	L	3'-5' exonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_1788729_10	469383.Cwoe_1839	1.959e-100	334.0	COG0526@1|root,COG0526@2|Bacteria,2GKDT@201174|Actinobacteria,4CRTZ@84995|Rubrobacteria	84995|Rubrobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMS3_k127_1873545_4	469383.Cwoe_3221	1.479e-193	610.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CP7T@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
MMS3_k127_1873545_36	469383.Cwoe_3223	3.769e-31	129.0	COG0858@1|root,COG0858@2|Bacteria,2HPFC@201174|Actinobacteria,4CQTS@84995|Rubrobacteria	84995|Rubrobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
MMS3_k127_1873545_12	469383.Cwoe_3224	1.739e-136	441.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4CPFM@84995|Rubrobacteria	84995|Rubrobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
MMS3_k127_1873545_27	1380390.JIAT01000010_gene4838	5.192e-72	252.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CPY4@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_N
MMS3_k127_1873545_16	1283299.AUKG01000002_gene5185	1.401e-112	374.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CPIB@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
MMS3_k127_1873545_32	929712.KI912613_gene3565	9.559e-38	147.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CQF0@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
MMS3_k127_1873545_29	469383.Cwoe_3229	1.076e-59	212.0	COG1225@1|root,COG1225@2|Bacteria,2HG0X@201174|Actinobacteria,4CTWJ@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS3_k127_1873545_0	1380390.JIAT01000010_gene4832	0.0	1107.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CPRU@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
MMS3_k127_1873545_11	469383.Cwoe_3233	2.465e-157	510.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CPQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1873545_25	469383.Cwoe_3234	1.702e-89	319.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CQJH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
MMS3_k127_1873545_20	1123023.JIAI01000002_gene5106	3.425e-103	344.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4E2HM@85010|Pseudonocardiales	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_1873545_2	1122939.ATUD01000005_gene2735	2.272e-233	735.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CPQX@84995|Rubrobacteria	84995|Rubrobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
MMS3_k127_1873545_13	469383.Cwoe_3239	9.292e-125	417.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4CR95@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1873545_14	469383.Cwoe_3240	1.548e-115	379.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CPKW@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1873545_1	469383.Cwoe_3241	2.279e-292	933.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CPHQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
MMS3_k127_1873545_30	469383.Cwoe_3243	3.016e-57	208.0	COG1426@1|root,COG1426@2|Bacteria,2HNYG@201174|Actinobacteria,4CQ7X@84995|Rubrobacteria	84995|Rubrobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
MMS3_k127_1873545_10	469383.Cwoe_3244	5.78e-160	518.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4CPMK@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
MMS3_k127_1873545_35	1122939.ATUD01000003_gene3642	8.901e-32	135.0	COG1514@1|root,COG1514@2|Bacteria,2HNKJ@201174|Actinobacteria,4CQT5@84995|Rubrobacteria	84995|Rubrobacteria	J	LigT like Phosphoesterase	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
MMS3_k127_1873545_7	1380390.JIAT01000010_gene4814	5.939e-183	579.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CPF2@84995|Rubrobacteria	84995|Rubrobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
MMS3_k127_1873545_38	1121924.ATWH01000009_gene109	4.878e-10	64.0	COG2337@1|root,COG2337@2|Bacteria,2IR5D@201174|Actinobacteria,4FQI6@85023|Microbacteriaceae	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
MMS3_k127_1873545_3	469383.Cwoe_3249	8.433e-221	692.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CPXU@84995|Rubrobacteria	84995|Rubrobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
MMS3_k127_1873545_23	469383.Cwoe_3253	1.583e-93	317.0	COG0300@1|root,COG0300@2|Bacteria,2I64P@201174|Actinobacteria,4CRW3@84995|Rubrobacteria	84995|Rubrobacteria	S	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_1873545_24	469383.Cwoe_3255	2.15e-92	310.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CQW4@84995|Rubrobacteria	84995|Rubrobacteria	J	IPP transferase	-	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
MMS3_k127_1873545_18	1380390.JIAT01000010_gene4801	4.405e-105	350.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4CQMD@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
MMS3_k127_1873545_6	469383.Cwoe_3257	2.618e-186	588.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CP8N@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_1873545_8	1380390.JIAT01000010_gene4793	1.246e-175	560.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CPXQ@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
MMS3_k127_1873545_33	1140.Synpcc7942_0099	1.862e-34	138.0	COG1694@1|root,COG1694@2|Bacteria,1G25W@1117|Cyanobacteria,1H41T@1129|Synechococcus	1117|Cyanobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
MMS3_k127_1873545_37	469383.Cwoe_3646	2.91e-13	78.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
MMS3_k127_1873545_34	469383.Cwoe_3647	5.298e-34	141.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1873545_26	469383.Cwoe_3648	2.718e-74	256.0	COG1136@1|root,COG1136@2|Bacteria,2GNB3@201174|Actinobacteria,4CU2E@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1873545_5	469383.Cwoe_5621	9.047e-187	612.0	COG4591@1|root,COG4591@2|Bacteria,2I6IU@201174|Actinobacteria	201174|Actinobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1873545_17	469383.Cwoe_3650	1.449e-105	373.0	2C5HJ@1|root,2Z812@2|Bacteria	2|Bacteria	S	Tetraprenyl-beta-curcumene synthase	ytpB	-	4.2.3.130	ko:K16188	-	-	R10009	RC02994	ko00000,ko01000	-	-	-	DUF2600
MMS3_k127_1873545_15	469383.Cwoe_5591	7.568e-115	401.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_1873545_31	1463917.JODC01000041_gene2958	2.182e-55	205.0	COG1414@1|root,COG1414@2|Bacteria,2IBUX@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMS3_k127_1873545_19	1283299.AUKG01000002_gene5137	7.814e-105	352.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CPRV@84995|Rubrobacteria	84995|Rubrobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
MMS3_k127_1873545_9	469383.Cwoe_3270	4.417e-169	546.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CP8D@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
MMS3_k127_1873545_21	1283299.AUKG01000002_gene5134	2.365e-97	328.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CQ16@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
MMS3_k127_1873545_28	469383.Cwoe_3274	1.242e-66	232.0	2AX99@1|root,31P89@2|Bacteria,2HNSP@201174|Actinobacteria,4CQ0H@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1873545_22	469383.Cwoe_5791	1.273e-96	327.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_1891896_5	106370.Francci3_2568	2.22e-10	69.0	COG1432@1|root,COG1432@2|Bacteria,2GVRE@201174|Actinobacteria	201174|Actinobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
MMS3_k127_1891896_1	469383.Cwoe_0899	1.91e-204	645.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CS9X@84995|Rubrobacteria	84995|Rubrobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMS3_k127_1891896_2	469383.Cwoe_0900	2.825e-52	192.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4CT93@84995|Rubrobacteria	84995|Rubrobacteria	K	Nitrogen regulatory protein P-II	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
MMS3_k127_1891896_4	469383.Cwoe_1845	9.542e-36	146.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CTFG@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS3_k127_1891896_0	469383.Cwoe_1844	6.478e-207	648.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
MMS3_k127_1891896_3	1283299.AUKG01000002_gene3695	7.005e-38	148.0	COG1959@1|root,COG1959@2|Bacteria,2HQP9@201174|Actinobacteria,4CSAH@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMS3_k127_1954254_4	469383.Cwoe_3058	9.703e-47	172.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2GIUZ@201174|Actinobacteria,4CPMA@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
MMS3_k127_1954254_2	469383.Cwoe_3059	1.797e-55	198.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CQJK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
MMS3_k127_1954254_0	1283299.AUKG01000004_gene940	1.322e-108	364.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CPI6@84995|Rubrobacteria	84995|Rubrobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_1954254_1	1112274.KI911560_gene128	1.103e-84	294.0	COG1672@1|root,COG1672@2|Bacteria,1MWQD@1224|Proteobacteria,2VK8E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
MMS3_k127_1954254_6	118166.JH976537_gene2237	9.807e-05	51.0	2EIPJ@1|root,33CEZ@2|Bacteria,1GAKK@1117|Cyanobacteria,1HDQM@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
MMS3_k127_1954254_3	1463879.JOHP01000037_gene6922	3.216e-51	198.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TIR_2
MMS3_k127_2012371_28	1068980.ARVW01000001_gene1946	1.476e-46	178.0	COG2239@1|root,COG2239@2|Bacteria,2IC0D@201174|Actinobacteria,4E3NS@85010|Pseudonocardiales	201174|Actinobacteria	P	Acts as a magnesium transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2012371_4	1380390.JIAT01000001_gene5062	1.295e-195	618.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4CRDZ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2012371_7	1191523.MROS_0749	1.889e-140	466.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
MMS3_k127_2012371_16	2002.JOEQ01000014_gene5283	6.676e-90	317.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,4EFNQ@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMS3_k127_2012371_17	1111479.AXAR01000007_gene947	9.925e-85	309.0	COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli	91061|Bacilli	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
MMS3_k127_2012371_10	1137269.AZWL01000022_gene3485	1.047e-117	407.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
MMS3_k127_2012371_11	1120973.AQXL01000117_gene375	7.415e-116	384.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli	91061|Bacilli	C	Fe-S oxidoreductases	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
MMS3_k127_2012371_34	679197.HMPREF9336_01342	5.559e-29	129.0	COG0583@1|root,COG0583@2|Bacteria,2GMES@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_2012371_5	469383.Cwoe_1198	2.917e-157	520.0	COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria,4CU60@84995|Rubrobacteria	84995|Rubrobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMS3_k127_2012371_35	112098.XP_008613767.1	3.381e-21	109.0	COG1960@1|root,KOG0140@2759|Eukaryota	2759|Eukaryota	I	medium-chain-acyl-CoA dehydrogenase activity	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2012371_18	96561.Dole_0041	3.181e-68	251.0	COG1960@1|root,COG1960@2|Bacteria,1R59X@1224|Proteobacteria,42P22@68525|delta/epsilon subdivisions,2WKQN@28221|Deltaproteobacteria,2MJCR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2012371_37	1415780.JPOG01000001_gene965	1.398e-20	104.0	COG4689@1|root,COG4689@2|Bacteria,1R7YD@1224|Proteobacteria,1S1RP@1236|Gammaproteobacteria,1XADW@135614|Xanthomonadales	135614|Xanthomonadales	Q	Acetoacetate decarboxylase (ADC)	-	-	-	-	-	-	-	-	-	-	-	-	ADC
MMS3_k127_2012371_22	1380390.JIAT01000014_gene6237	5.22e-64	229.0	COG0500@1|root,COG2226@2|Bacteria,2HENT@201174|Actinobacteria,4CQIJ@84995|Rubrobacteria	84995|Rubrobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2012371_9	469383.Cwoe_1710	1.46e-125	444.0	COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,2HGJ9@201174|Actinobacteria,4CRYN@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_2012371_19	1380390.JIAT01000009_gene571	9.853e-67	236.0	COG0789@1|root,COG0789@2|Bacteria,2GKAU@201174|Actinobacteria,4CRRD@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMS3_k127_2012371_36	1038862.KB893806_gene2910	1.28e-20	109.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria,2U1BI@28211|Alphaproteobacteria,3JVY2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,TIG
MMS3_k127_2012371_27	622637.KE124774_gene3214	6.315e-50	205.0	COG1470@1|root,COG1470@2|Bacteria,1R174@1224|Proteobacteria,2UJ3T@28211|Alphaproteobacteria	1224|Proteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2012371_3	469383.Cwoe_5739	1.253e-209	658.0	COG3239@1|root,COG3239@2|Bacteria,2GIWV@201174|Actinobacteria,4CRJF@84995|Rubrobacteria	84995|Rubrobacteria	CI	Fatty acid desaturase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase,Rubredoxin
MMS3_k127_2012371_38	469383.Cwoe_5738	1.678e-19	99.0	COG1773@1|root,COG1773@2|Bacteria,2GQUH@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the rubredoxin family	alkG	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
MMS3_k127_2012371_23	469383.Cwoe_5737	1.711e-60	215.0	COG1309@1|root,COG1309@2|Bacteria,2GMDA@201174|Actinobacteria,4CT7V@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2012371_29	1380390.JIAT01000009_gene1908	3.523e-40	156.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4CR10@84995|Rubrobacteria	84995|Rubrobacteria	H	May be involved in the biosynthesis of molybdopterin	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
MMS3_k127_2012371_24	1283299.AUKG01000001_gene1878	6.005e-58	207.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CSG6@84995|Rubrobacteria	84995|Rubrobacteria	H	MoaC family	-	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
MMS3_k127_2012371_26	1380390.JIAT01000009_gene2174	4.003e-52	205.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2IQ9F@201174|Actinobacteria,4CQW8@84995|Rubrobacteria	84995|Rubrobacteria	H	molybdopterin biosynthesis MoaE	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
MMS3_k127_2012371_14	469383.Cwoe_4686	4.314e-96	329.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4CQ5A@84995|Rubrobacteria	84995|Rubrobacteria	H	molybdopterin binding domain	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
MMS3_k127_2012371_31	1122939.ATUD01000001_gene399	1.1e-33	149.0	COG0746@1|root,COG0746@2|Bacteria,2HPDS@201174|Actinobacteria,4CQRT@84995|Rubrobacteria	84995|Rubrobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
MMS3_k127_2012371_25	1291050.JAGE01000001_gene2868	1.588e-54	207.0	COG0826@1|root,COG0826@2|Bacteria,1VT61@1239|Firmicutes,24AZY@186801|Clostridia,3WRXE@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
MMS3_k127_2012371_42	1298860.AUEM01000002_gene900	1.79e-06	60.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FKZR@85023|Microbacteriaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD2	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2012371_43	543632.JOJL01000014_gene9220	7.25e-06	58.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4D8GT@85008|Micromonosporales	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K16428	ko01055,map01055	-	-	-	ko00000,ko00001	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
MMS3_k127_2012371_32	316055.RPE_3905	1.21e-31	141.0	COG1541@1|root,COG1541@2|Bacteria,1QYVU@1224|Proteobacteria,2TY02@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,LuxC
MMS3_k127_2012371_13	675635.Psed_1330	8.709e-102	349.0	arCOG06766@1|root,2Z87F@2|Bacteria,2IAM6@201174|Actinobacteria,4E7V9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2012371_2	96561.Dole_0194	1.091e-231	756.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
MMS3_k127_2012371_33	1348657.M622_05065	3.221e-31	132.0	COG3381@1|root,COG3381@2|Bacteria,1RAXF@1224|Proteobacteria,2VY6I@28216|Betaproteobacteria,2KXH2@206389|Rhodocyclales	206389|Rhodocyclales	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
MMS3_k127_2012371_6	1348657.M622_05005	1.426e-147	481.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2VJ1V@28216|Betaproteobacteria,2KVJ5@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S dicluster domain	-	-	-	ko:K17048,ko:K17051	ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220	-	R05745	RC00275	ko00000,ko00001,ko02000	5.A.3.8,5.A.3.9	-	-	Fer4_11
MMS3_k127_2012371_30	1348657.M622_05000	1.157e-34	144.0	COG2010@1|root,COG2010@2|Bacteria,1PE1B@1224|Proteobacteria,2W4M1@28216|Betaproteobacteria,2KZ62@206389|Rhodocyclales	206389|Rhodocyclales	C	Ethylbenzene dehydrogenase	-	-	-	ko:K17052	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	EB_dh
MMS3_k127_2012371_15	479432.Sros_7299	3.807e-92	323.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4EQV7@85012|Streptosporangiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
MMS3_k127_2012371_44	926569.ANT_14650	0.0002958	53.0	COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
MMS3_k127_2012371_12	479432.Sros_7299	7.419e-104	357.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4EQV7@85012|Streptosporangiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
MMS3_k127_2012371_1	96561.Dole_0194	2.326e-244	785.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
MMS3_k127_2012371_0	96561.Dole_0194	5.446e-262	839.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
MMS3_k127_2012371_40	1032480.MLP_10720	2.811e-07	61.0	COG2197@1|root,COG2197@2|Bacteria,2GJ5I@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_2012371_20	439235.Dalk_3834	1.093e-65	243.0	COG1960@1|root,COG1960@2|Bacteria,1R59X@1224|Proteobacteria,42P22@68525|delta/epsilon subdivisions,2WKQN@28221|Deltaproteobacteria,2MJCR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2012371_8	1000565.METUNv1_04052	2.299e-138	447.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
MMS3_k127_2012371_21	469383.Cwoe_3462	2.11e-65	230.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,4CT6E@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
MMS3_k127_202912_0	469383.Cwoe_2878	3.065e-107	356.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,4CPZF@84995|Rubrobacteria	84995|Rubrobacteria	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
MMS3_k127_202912_3	1123508.JH636459_gene184	1.099e-06	55.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K15546,ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	Cupin_2,HTH_3,HTH_31
MMS3_k127_202912_2	543632.JOJL01000042_gene4589	1.509e-52	198.0	COG1414@1|root,COG1414@2|Bacteria,2IBUX@201174|Actinobacteria,4DM63@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMS3_k127_202912_1	469383.Cwoe_5591	8.564e-93	316.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2061457_2	1283299.AUKG01000002_gene4961	8.771e-41	152.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CQ53@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
MMS3_k127_2061457_4	469383.Cwoe_3488	5.44e-28	119.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
MMS3_k127_2061457_0	469383.Cwoe_5413	4.678e-166	539.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria,4CRNG@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_2061457_5	469383.Cwoe_3485	2.306e-07	63.0	COG1595@1|root,COG1595@2|Bacteria,2HRN2@201174|Actinobacteria,4CTQ5@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2061457_3	929712.KI912613_gene3891	2.757e-38	148.0	COG2050@1|root,COG2050@2|Bacteria,2HQVR@201174|Actinobacteria,4CSNV@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_2061457_1	469383.Cwoe_3480	8.486e-95	317.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
MMS3_k127_2083679_0	1380390.JIAT01000010_gene4853	6.011e-266	827.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CPEA@84995|Rubrobacteria	84995|Rubrobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
MMS3_k127_2083679_4	471852.Tcur_0288	3.259e-114	401.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4EHA4@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMS3_k127_2083679_7	1283299.AUKG01000002_gene5199	5.366e-42	158.0	2AU98@1|root,31JWM@2|Bacteria,2HNY8@201174|Actinobacteria,4CQ7F@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2083679_5	469383.Cwoe_3208	3.148e-73	257.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CQ9S@84995|Rubrobacteria	84995|Rubrobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
MMS3_k127_2083679_9	1283299.AUKG01000002_gene5197	4.328e-38	144.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4CQGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
MMS3_k127_2083679_2	469383.Cwoe_3211	1.533e-154	498.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4CQAJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
MMS3_k127_2083679_8	1283299.AUKG01000002_gene5192	7.345e-41	154.0	COG0457@1|root,COG0457@2|Bacteria,2IQ48@201174|Actinobacteria,4CSUA@84995|Rubrobacteria	84995|Rubrobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2083679_6	1122939.ATUD01000005_gene2716	1.248e-48	184.0	COG0779@1|root,COG0779@2|Bacteria,2HPFT@201174|Actinobacteria,4CQU9@84995|Rubrobacteria	84995|Rubrobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
MMS3_k127_2083679_1	469383.Cwoe_3219	8.802e-209	663.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CPEF@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
MMS3_k127_2083679_3	469383.Cwoe_3221	1.453e-122	408.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CP7T@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
MMS3_k127_2197638_3	1122165.AUHS01000003_gene1982	1.831e-06	56.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1JEBZ@118969|Legionellales	118969|Legionellales	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
MMS3_k127_2197638_2	469383.Cwoe_5209	6.649e-88	306.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CPJE@84995|Rubrobacteria	84995|Rubrobacteria	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
MMS3_k127_2197638_0	469383.Cwoe_5210	4.391e-267	831.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4CRM8@84995|Rubrobacteria	84995|Rubrobacteria	EH	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_2197638_1	469383.Cwoe_5221	9.19e-123	415.0	COG1595@1|root,COG1595@2|Bacteria,2GJFK@201174|Actinobacteria,4CPHK@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2249746_7	656024.FsymDg_4517	2.243e-36	140.0	COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria	201174|Actinobacteria	J	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS3_k127_2249746_5	469383.Cwoe_1085	2.153e-67	241.0	COG0524@1|root,COG0524@2|Bacteria,2H514@201174|Actinobacteria,4CT2F@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_2249746_8	1075090.GOAMR_76_00560	4.554e-25	109.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria,4GGRX@85026|Gordoniaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
MMS3_k127_2249746_3	469383.Cwoe_4041	3.76e-94	321.0	COG0604@1|root,COG0604@2|Bacteria,2GMA2@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
MMS3_k127_2249746_1	469383.Cwoe_3875	9.068e-123	409.0	COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria	201174|Actinobacteria	J	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS3_k127_2249746_0	318586.Pden_3833	1.187e-160	515.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria,2PVEN@265|Paracoccus	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS3_k127_2249746_2	106370.Francci3_2444	2.425e-99	328.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4ETTD@85013|Frankiales	201174|Actinobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_2249746_4	106370.Francci3_2445	2.415e-69	254.0	COG0642@1|root,COG2205@2|Bacteria,2GJMV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_2249746_9	1394178.AWOO02000027_gene5204	4.719e-09	66.0	2EBG5@1|root,335GQ@2|Bacteria,2GRUT@201174|Actinobacteria,4EK3Z@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2249746_6	469383.Cwoe_0225	1.08e-42	167.0	COG3409@1|root,COG3409@2|Bacteria,2I9HW@201174|Actinobacteria	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,PG_binding_1
MMS3_k127_2252637_3	1463917.JODC01000041_gene2958	3.251e-53	203.0	COG1414@1|root,COG1414@2|Bacteria,2IBUX@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMS3_k127_2252637_4	1283299.AUKG01000001_gene2035	1.7e-14	78.0	2AV4F@1|root,31KUK@2|Bacteria,2HPDR@201174|Actinobacteria,4CQRR@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2252637_1	469383.Cwoe_5789	8.199e-163	519.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CPRY@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_2252637_8	1089553.Tph_c02080	9.381e-07	53.0	COG3905@1|root,COG3905@2|Bacteria,1W0YQ@1239|Firmicutes,253QQ@186801|Clostridia,42INM@68295|Thermoanaerobacterales	186801|Clostridia	K	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
MMS3_k127_2252637_7	926550.CLDAP_20150	1.941e-08	61.0	COG1569@1|root,COG1569@2|Bacteria,2G7HZ@200795|Chloroflexi	200795|Chloroflexi	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
MMS3_k127_2252637_6	247490.KSU1_D0247	5.06e-09	63.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
MMS3_k127_2252637_5	266117.Rxyl_1594	1.341e-13	76.0	COG4634@1|root,COG4634@2|Bacteria,2H0F6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2252637_2	469383.Cwoe_5788	1.863e-88	304.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,4CPVG@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
MMS3_k127_2252637_0	469383.Cwoe_5787	1.685e-182	576.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CPTQ@84995|Rubrobacteria	84995|Rubrobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_226829_1	76114.ebD37	1.055e-23	104.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	HEPN,NTP_transf_2
MMS3_k127_226829_2	469383.Cwoe_3961	4.445e-18	91.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
MMS3_k127_226829_0	1380390.JIAT01000012_gene3300	3.392e-69	244.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
MMS3_k127_2297696_1	1123023.JIAI01000021_gene2351	2.649e-153	491.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4DXWP@85010|Pseudonocardiales	201174|Actinobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,NAD_binding_8,Pyr_redox_2,Pyr_redox_3
MMS3_k127_2297696_0	1122939.ATUD01000017_gene4019	1.946e-252	787.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4CPDW@84995|Rubrobacteria	84995|Rubrobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMS3_k127_2297696_4	1283299.AUKG01000001_gene2149	1.09e-57	203.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4CQ50@84995|Rubrobacteria	84995|Rubrobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_2297696_6	441768.ACL_0759	0.0001045	54.0	COG1277@1|root,COG1277@2|Bacteria,3WUUS@544448|Tenericutes	544448|Tenericutes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_2297696_2	1121019.AUMN01000003_gene1012	7.572e-96	328.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,1W8KA@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2297696_3	1179773.BN6_07170	1.205e-83	295.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria,4E10C@85010|Pseudonocardiales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4,Peptidase_S9
MMS3_k127_2316694_22	1122939.ATUD01000002_gene1191	7.284e-95	317.0	COG1387@1|root,COG1387@2|Bacteria,2IR14@201174|Actinobacteria,4CQ7N@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidinol phosphate phosphatase, HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
MMS3_k127_2316694_27	469383.Cwoe_1688	9.903e-66	231.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CQE7@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
MMS3_k127_2316694_23	469383.Cwoe_1687	2.56e-81	276.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CPVJ@84995|Rubrobacteria	84995|Rubrobacteria	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
MMS3_k127_2316694_4	1380390.JIAT01000011_gene2865	1.078e-187	601.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4CPEN@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA integrity scanning protein DisA	-	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH_2
MMS3_k127_2316694_7	469383.Cwoe_1685	2.762e-174	560.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CP8Q@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
MMS3_k127_2316694_0	679197.HMPREF9336_01889	0.0	1057.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria	201174|Actinobacteria	O	associated with various cellular activities	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
MMS3_k127_2316694_2	469383.Cwoe_1681	1.572e-205	649.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CR5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS3_k127_2316694_28	1283299.AUKG01000001_gene2943	1.175e-63	223.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CQG1@84995|Rubrobacteria	84995|Rubrobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
MMS3_k127_2316694_16	929712.KI912613_gene4792	3.28e-122	402.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4CPE8@84995|Rubrobacteria	84995|Rubrobacteria	J	Dihydrouridine synthase (Dus)	-	-	-	-	-	-	-	-	-	-	-	-	Dus
MMS3_k127_2316694_17	1380390.JIAT01000011_gene2850	3.163e-117	381.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CQ5C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
MMS3_k127_2316694_34	929712.KI912613_gene4795	4.002e-53	199.0	COG0625@1|root,COG0625@2|Bacteria,2HQWF@201174|Actinobacteria,4CSPC@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
MMS3_k127_2316694_15	469383.Cwoe_4655	1.253e-132	429.0	COG0500@1|root,COG2226@2|Bacteria,2HPV9@201174|Actinobacteria,4CR9D@84995|Rubrobacteria	84995|Rubrobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2316694_30	391598.FBBAL38_08809	2.913e-58	227.0	COG1470@1|root,COG2133@1|root,COG2304@1|root,COG2706@1|root,COG3209@1|root,COG3291@1|root,COG3420@1|root,COG4733@1|root,COG5279@1|root,COG1470@2|Bacteria,COG2133@2|Bacteria,COG2304@2|Bacteria,COG2706@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,COG5279@2|Bacteria,4P2UU@976|Bacteroidetes,1HYAX@117743|Flavobacteriia	976|Bacteroidetes	DZ	TIGRFAM Bacterial surface protein 26-residue repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,DUF285,TIG,TSP_3
MMS3_k127_2316694_26	469383.Cwoe_4663	2.771e-68	238.0	COG2802@1|root,COG2802@2|Bacteria,2HP4R@201174|Actinobacteria,4CQGD@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
MMS3_k127_2316694_6	469383.Cwoe_4666	2.243e-174	560.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4CPY9@84995|Rubrobacteria	84995|Rubrobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_2316694_5	469383.Cwoe_4667	1.327e-180	578.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CRHI@84995|Rubrobacteria	84995|Rubrobacteria	D	Tubulin/FtsZ family, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsZ_C,Tubulin
MMS3_k127_2316694_13	469383.Cwoe_4668	1.158e-136	445.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CPVA@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMS3_k127_2316694_19	1380390.JIAT01000009_gene419	6.616e-112	374.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,4CPUJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
MMS3_k127_2316694_24	1380390.JIAT01000009_gene421	1.358e-72	267.0	2ATZV@1|root,31JJQ@2|Bacteria,2HNRB@201174|Actinobacteria,4CPYQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2316694_33	1283299.AUKG01000002_gene3797	1.609e-55	196.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria,4CQEM@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
MMS3_k127_2316694_10	1283299.AUKG01000002_gene3795	4.593e-159	510.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria,4CP76@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMS3_k127_2316694_3	1283299.AUKG01000002_gene3794	3.428e-196	617.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_2316694_45	1380390.JIAT01000009_gene430	4.758e-22	102.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CSFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
MMS3_k127_2316694_29	570268.ANBB01000027_gene700	4.531e-59	214.0	COG2227@1|root,COG2227@2|Bacteria,2H167@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMS3_k127_2316694_44	1380390.JIAT01000009_gene431	4.269e-25	117.0	COG2199@1|root,COG3706@2|Bacteria,2HQH1@201174|Actinobacteria,4CS22@84995|Rubrobacteria	84995|Rubrobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2316694_32	469383.Cwoe_4687	1.271e-57	223.0	2EIFC@1|root,33C6Q@2|Bacteria,2HQ1J@201174|Actinobacteria,4CRHT@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2316694_11	469383.Cwoe_4688	4.541e-150	482.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4CP7Y@84995|Rubrobacteria	84995|Rubrobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
MMS3_k127_2316694_1	1283299.AUKG01000002_gene3769	7.977e-236	740.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CPHW@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
MMS3_k127_2316694_21	1380390.JIAT01000009_gene450	3.009e-100	344.0	COG3429@1|root,COG3429@2|Bacteria,2HYJH@201174|Actinobacteria,4CPZH@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
MMS3_k127_2316694_36	1283299.AUKG01000002_gene3765	6.689e-48	180.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4CQA7@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
MMS3_k127_2316694_12	1283299.AUKG01000002_gene3752	2.577e-141	458.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4CPQ7@84995|Rubrobacteria	84995|Rubrobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
MMS3_k127_2316694_14	1283299.AUKG01000002_gene3751	1.279e-134	438.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,4CPCZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Histidine-specific methyltransferase, SAM-dependent	-	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
MMS3_k127_2316694_20	1382356.JQMP01000003_gene1765	2.646e-110	381.0	COG3118@1|root,COG3118@2|Bacteria,2G8FS@200795|Chloroflexi	200795|Chloroflexi	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
MMS3_k127_2316694_18	1283299.AUKG01000002_gene3748	1.318e-114	379.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4CPHJ@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2316694_9	1122939.ATUD01000017_gene3986	2.584e-164	528.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CRJ5@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_2316694_25	1380390.JIAT01000009_gene499	8.407e-71	247.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4CQ0S@84995|Rubrobacteria	84995|Rubrobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
MMS3_k127_2316694_41	83332.Rv0665	3.011e-37	147.0	COG1487@1|root,COG1487@2|Bacteria,2HC5H@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_2316694_48	469383.Cwoe_4818	5.317e-12	68.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0015643,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
MMS3_k127_2316694_43	1500259.JQLD01000001_gene3752	8.767e-27	123.0	COG0582@1|root,COG0582@2|Bacteria,1RBMJ@1224|Proteobacteria,2U0ET@28211|Alphaproteobacteria,4BCUG@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS3_k127_2316694_47	1122939.ATUD01000014_gene1102	9.313e-14	84.0	2ECCS@1|root,336B1@2|Bacteria,2IT5V@201174|Actinobacteria,4CTKI@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2316694_42	1283299.AUKG01000001_gene2364	2.016e-33	138.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
MMS3_k127_2316694_39	469383.Cwoe_3414	6.103e-40	164.0	COG1595@1|root,COG1595@2|Bacteria,2ICFT@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2316694_49	929712.KI912613_gene1432	6.29e-11	75.0	2A3Z2@1|root,30SHH@2|Bacteria,2HRN5@201174|Actinobacteria,4CTQ9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2316694_35	1172180.KB911775_gene5849	8.025e-53	208.0	2BKQM@1|root,32F6D@2|Bacteria,2H1PN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2316694_40	1048339.KB913029_gene3727	1.638e-38	149.0	COG4974@1|root,COG4974@2|Bacteria,2I9XB@201174|Actinobacteria,4ESZK@85013|Frankiales	201174|Actinobacteria	L	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
MMS3_k127_2316694_38	469383.Cwoe_3414	1.854e-40	156.0	COG1595@1|root,COG1595@2|Bacteria,2ICFT@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2316694_50	1047013.AQSP01000138_gene1023	6.407e-11	74.0	2DEQR@1|root,2ZNVU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2316694_31	953739.SVEN_6179	4.846e-58	217.0	2EY3A@1|root,33RC7@2|Bacteria,2I9GS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2316694_37	1283299.AUKG01000001_gene1286	2.735e-46	172.0	COG3837@1|root,COG3837@2|Bacteria	2|Bacteria	S	Cupin domain	manC	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_2316694_46	1384054.N790_01760	2.486e-18	88.0	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,1RR6A@1236|Gammaproteobacteria,1X6KZ@135614|Xanthomonadales	135614|Xanthomonadales	M	acetyltransferase	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
MMS3_k127_2316694_52	136993.KB900626_gene3824	6.529e-07	59.0	COG1309@1|root,COG1309@2|Bacteria,1NB71@1224|Proteobacteria,2UBX7@28211|Alphaproteobacteria,370TW@31993|Methylocystaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2316694_8	1379270.AUXF01000001_gene2443	9.044e-169	539.0	COG1819@1|root,COG1819@2|Bacteria	2|Bacteria	CG	transferase activity, transferring hexosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
MMS3_k127_2327519_4	469383.Cwoe_1309	1.341e-163	525.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
MMS3_k127_2327519_6	469383.Cwoe_4990	1.291e-134	436.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
MMS3_k127_2327519_9	469383.Cwoe_1541	2.91e-86	292.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4CQ8G@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_2327519_0	1150398.JIBJ01000003_gene1738	1.299e-259	818.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,1W81Y@1268|Micrococcaceae	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
MMS3_k127_2327519_10	1283299.AUKG01000001_gene2722	3.235e-75	258.0	COG1051@1|root,COG1051@2|Bacteria,2HQ01@201174|Actinobacteria,4CRFN@84995|Rubrobacteria	84995|Rubrobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_2327519_16	469383.Cwoe_1559	3.949e-27	123.0	COG1773@1|root,COG1773@2|Bacteria,2GSAE@201174|Actinobacteria	201174|Actinobacteria	C	Rubredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
MMS3_k127_2327519_3	67373.JOBF01000002_gene1359	3.254e-171	549.0	COG0161@1|root,COG0161@2|Bacteria,2I2DN@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	GO:0003674,GO:0003824,GO:0004015,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_2327519_13	1380390.JIAT01000011_gene2669	2.647e-61	219.0	COG0132@1|root,COG0132@2|Bacteria,2GIZ2@201174|Actinobacteria,4CRYX@84995|Rubrobacteria	84995|Rubrobacteria	H	AAA domain	-	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
MMS3_k127_2327519_5	469383.Cwoe_1570	5.596e-156	505.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4CR0Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_2327519_2	469383.Cwoe_1571	1.579e-206	652.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4CR7S@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
MMS3_k127_2327519_8	1380390.JIAT01000011_gene2677	2.616e-99	334.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4CPUH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_2327519_15	1380390.JIAT01000011_gene2678	1.708e-30	121.0	COG4770@1|root,COG4770@2|Bacteria,2HRMS@201174|Actinobacteria,4CTPT@84995|Rubrobacteria	84995|Rubrobacteria	I	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
MMS3_k127_2327519_12	469383.Cwoe_1577	3.813e-62	226.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_2327519_1	929712.KI912613_gene4887	1.002e-206	653.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4CPBQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
MMS3_k127_2327519_7	1380390.JIAT01000011_gene2679	3.937e-105	347.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria,4CP9N@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS3_k127_2327519_14	1380390.JIAT01000015_gene5755	4.982e-38	160.0	2B412@1|root,31WRB@2|Bacteria,2HY97@201174|Actinobacteria,4CQGQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2327519_11	469383.Cwoe_1585	6.269e-64	220.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4CPAT@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_2411312_1	469383.Cwoe_3114	4.225e-149	483.0	COG1819@1|root,COG1819@2|Bacteria,2I8EN@201174|Actinobacteria,4CPRE@84995|Rubrobacteria	84995|Rubrobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
MMS3_k127_2411312_0	469383.Cwoe_3116	1.431e-179	567.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4CPP7@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2411312_2	469383.Cwoe_3117	2.722e-96	325.0	COG4221@1|root,COG4221@2|Bacteria,2I5BD@201174|Actinobacteria,4CPN3@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2411312_3	1380390.JIAT01000014_gene6258	1.166e-41	166.0	COG0204@1|root,COG0240@1|root,COG0204@2|Bacteria,COG0240@2|Bacteria,2GJ6V@201174|Actinobacteria,4CP70@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
MMS3_k127_2413650_39	1448389.BAVQ01000015_gene4130	7.137e-06	53.0	2D089@1|root,32T81@2|Bacteria,2IHKJ@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
MMS3_k127_2413650_24	1137268.AZXF01000013_gene1632	1.393e-52	193.0	COG5340@1|root,COG5340@2|Bacteria,2ISM9@201174|Actinobacteria,4EKYR@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
MMS3_k127_2413650_28	1122939.ATUD01000001_gene15	7.621e-40	152.0	COG2337@1|root,COG2337@2|Bacteria,2IQQ9@201174|Actinobacteria	201174|Actinobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005576,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0045927,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
MMS3_k127_2413650_37	1121924.ATWH01000001_gene4348	1.772e-13	72.0	COG0864@1|root,COG0864@2|Bacteria,2GZCR@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
MMS3_k127_2413650_40	1380390.JIAT01000012_gene3211	0.0003244	48.0	COG5470@1|root,COG5470@2|Bacteria,2IM3I@201174|Actinobacteria,4CQGY@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
MMS3_k127_2413650_4	1048339.KB913029_gene2193	1.794e-189	610.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ERI3@85013|Frankiales	201174|Actinobacteria	IQ	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2413650_7	1295642.H839_13569	3.683e-158	534.0	COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,4HBKB@91061|Bacilli,1WGC8@129337|Geobacillus	91061|Bacilli	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_2413650_2	106370.Francci3_2239	8.611e-196	641.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4ERWZ@85013|Frankiales	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_2413650_27	1158292.JPOE01000002_gene2326	1.133e-40	170.0	COG4647@1|root,COG4647@2|Bacteria,1RD95@1224|Proteobacteria,2VW6C@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Acetone carboxylase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Acetone_carb_G
MMS3_k127_2413650_13	1071085.KK033114_gene1030	1.672e-109	378.0	COG0145@1|root,arCOG01511@2157|Archaea,2Y2KR@28890|Euryarchaeota,23Z73@183963|Halobacteria	183963|Halobacteria	E	Hydantoinase/oxoprolinase N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_2413650_11	1123024.AUII01000021_gene83	2.563e-128	422.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4E1YW@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_2413650_33	436717.AOLE_09495	8.163e-28	122.0	COG1309@1|root,COG1309@2|Bacteria,1NE0F@1224|Proteobacteria,1S9XP@1236|Gammaproteobacteria,3NKUC@468|Moraxellaceae	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2413650_30	1283299.AUKG01000003_gene530	2.209e-37	151.0	2FE1I@1|root,32SFH@2|Bacteria,2I8AE@201174|Actinobacteria,4CTZH@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2413650_21	882082.SaccyDRAFT_2940	6.014e-73	258.0	COG4976@1|root,COG4976@2|Bacteria,2IGUS@201174|Actinobacteria,4E3AJ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
MMS3_k127_2413650_25	1242864.D187_001851	3.163e-51	192.0	COG1028@1|root,COG1028@2|Bacteria	1242864.D187_001851|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2413650_26	316067.Geob_2070	8.641e-50	186.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,42VMX@68525|delta/epsilon subdivisions,2WS5W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
MMS3_k127_2413650_22	1419583.V466_19000	8.484e-69	247.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,1RZUZ@1236|Gammaproteobacteria,1YMRD@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	V	beta-lactamase	estC	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_2413650_15	1206730.BAGA01000177_gene4621	6.897e-100	332.0	COG1028@1|root,COG1028@2|Bacteria,2I2QN@201174|Actinobacteria,4G9FD@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2413650_18	1169152.AXVD01000032_gene3270	3.382e-84	288.0	COG0300@1|root,COG0300@2|Bacteria,2I2PB@201174|Actinobacteria,4G9F3@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2413650_5	469383.Cwoe_2408	1.568e-172	553.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CRYD@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
MMS3_k127_2413650_8	469383.Cwoe_2409	9.246e-154	524.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
MMS3_k127_2413650_10	42256.RradSPS_0484	5.709e-129	424.0	COG2837@1|root,COG2837@2|Bacteria,2GIUB@201174|Actinobacteria,4CP9V@84995|Rubrobacteria	84995|Rubrobacteria	P	Dyp-type peroxidase family	-	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox
MMS3_k127_2413650_1	469383.Cwoe_1198	1.348e-203	646.0	COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria,4CU60@84995|Rubrobacteria	84995|Rubrobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMS3_k127_2413650_20	405948.SACE_3673	1.828e-77	278.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
MMS3_k127_2413650_14	469383.Cwoe_4977	1.95e-100	344.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,4CQPJ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
MMS3_k127_2413650_17	1380390.JIAT01000010_gene4086	1.177e-84	289.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMS3_k127_2413650_38	543632.JOJL01000042_gene4589	1.977e-07	63.0	COG1414@1|root,COG1414@2|Bacteria,2IBUX@201174|Actinobacteria,4DM63@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMS3_k127_2413650_19	1122939.ATUD01000002_gene1122	7.998e-78	273.0	COG0392@1|root,COG0438@1|root,COG0392@2|Bacteria,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CPA3@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,LPG_synthase_TM
MMS3_k127_2413650_6	351607.Acel_1699	7.291e-170	537.0	COG0535@1|root,COG0535@2|Bacteria,2HTDD@201174|Actinobacteria,4ES4M@85013|Frankiales	201174|Actinobacteria	F	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_14,Radical_SAM
MMS3_k127_2413650_32	1146883.BLASA_0210	4.751e-30	131.0	COG0535@1|root,COG0775@1|root,COG0535@2|Bacteria,COG0775@2|Bacteria,2HTDD@201174|Actinobacteria,4ES4M@85013|Frankiales	201174|Actinobacteria	F	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_14,Radical_SAM
MMS3_k127_2413650_12	675635.Psed_3678	1.555e-121	411.0	COG1232@1|root,COG1232@2|Bacteria,2I2Z5@201174|Actinobacteria,4E1XZ@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM squalene-associated FAD-dependent desaturase	hopC	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMS3_k127_2413650_9	414996.IL38_07220	2.102e-146	485.0	COG1562@1|root,COG1562@2|Bacteria,2I290@201174|Actinobacteria,408UW@622450|Actinopolysporales	201174|Actinobacteria	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
MMS3_k127_2413650_0	351607.Acel_1697	1.032e-265	837.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria,4ES7V@85013|Frankiales	201174|Actinobacteria	I	Squalene--hopene cyclase	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
MMS3_k127_2413650_23	469383.Cwoe_5505	1.607e-64	242.0	COG5305@1|root,COG5305@2|Bacteria,2HPE5@201174|Actinobacteria,4CQS9@84995|Rubrobacteria	84995|Rubrobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_2413650_31	1283299.AUKG01000001_gene2557	5.663e-37	156.0	2DKYN@1|root,30WXH@2|Bacteria,2HQHS@201174|Actinobacteria,4CS33@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS3_k127_2413650_3	1133849.O3I_021245	7.244e-190	606.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FTXB@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_2413650_16	644966.Tmar_1515	9.038e-95	321.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,24AY7@186801|Clostridia,3WDFJ@538999|Clostridiales incertae sedis	186801|Clostridia	C	Alcohol dehydrogenase GroES-like domain	adhB	-	1.1.1.1,1.1.1.284,1.2.1.46	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00604,R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00188,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
MMS3_k127_2413650_36	1089551.KE386572_gene649	4.223e-18	96.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,4BQ8Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
MMS3_k127_2413650_29	66897.DJ64_33060	1.617e-39	163.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria	201174|Actinobacteria	CG	Glycosyltransferase, MGT family	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
MMS3_k127_2452265_2	469383.Cwoe_4032	1.15e-154	497.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_2452265_1	469383.Cwoe_0827	5.534e-205	651.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CPP3@84995|Rubrobacteria	84995|Rubrobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
MMS3_k127_2452265_3	1380390.JIAT01000009_gene1478	1.658e-79	274.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4CQ5M@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
MMS3_k127_2452265_0	1283299.AUKG01000001_gene1428	5.902e-235	737.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CPN1@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
MMS3_k127_2462121_1	1440774.Y900_027885	7.219e-164	527.0	COG0674@1|root,COG0674@2|Bacteria,2I995@201174|Actinobacteria,237Z9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,PFOR_II,POR,POR_N,TPP_enzyme_C
MMS3_k127_2462121_4	395495.Lcho_2149	3.724e-70	243.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2VQ8C@28216|Betaproteobacteria,1KKPN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.1.58,1.2.7.1	ko:K00172,ko:K18357	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
MMS3_k127_2462121_0	483219.LILAB_12465	1.896e-221	712.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria,2YW7G@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2101	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS3_k127_2462121_3	469383.Cwoe_1860	2.924e-94	319.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CPNM@84995|Rubrobacteria	84995|Rubrobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
MMS3_k127_2462121_2	1380390.JIAT01000009_gene2065	2.681e-144	471.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRC3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2515586_13	1120971.AUCA01000001_gene1766	7.2e-07	56.0	COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,4HCEY@91061|Bacilli,279M3@186823|Alicyclobacillaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	ykcB	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_2515586_0	1283299.AUKG01000001_gene1271	2.712e-181	583.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4CPTE@84995|Rubrobacteria	84995|Rubrobacteria	FP	Ppx/GppA phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	HD,Ppx-GppA
MMS3_k127_2515586_12	391595.RLO149_c028240	2.616e-08	59.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,2VBT7@28211|Alphaproteobacteria,2P54U@2433|Roseobacter	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMS3_k127_2515586_9	266117.Rxyl_2320	4e-25	111.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4CQKQ@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_2515586_2	1121877.JQKF01000028_gene2148	8.746e-85	304.0	COG1376@1|root,COG1376@2|Bacteria,2GWPY@201174|Actinobacteria,4CNN9@84992|Acidimicrobiia	84992|Acidimicrobiia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_2515586_7	1283299.AUKG01000004_gene1193	2.65e-51	201.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_2515586_6	395964.KE386496_gene2823	1.596e-63	237.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,2U5QZ@28211|Alphaproteobacteria,3NB5N@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
MMS3_k127_2515586_4	1415166.NONO_c27910	1.618e-81	280.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4FWJ9@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127,1.1.1.304,1.1.1.53,1.1.1.76	ko:K00038,ko:K00065,ko:K18009	ko00040,ko00140,ko00650,ko01100,map00040,map00140,map00650,map01100	-	R01542,R03707,R04831,R04834,R04844,R04847,R09078,R10505	RC00089,RC00139,RC00205,RC00525,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
MMS3_k127_2515586_11	339670.Bamb_4039	1.457e-21	109.0	COG0627@1|root,COG0627@2|Bacteria,1R4M6@1224|Proteobacteria,2VXSW@28216|Betaproteobacteria,1K1MQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Esterase	-	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
MMS3_k127_2515586_8	469383.Cwoe_5886	1.109e-44	183.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4CQCM@84995|Rubrobacteria	84995|Rubrobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
MMS3_k127_2515586_3	471852.Tcur_0154	1.453e-83	290.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria,4EHZ1@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
MMS3_k127_2515586_5	103733.JNYO01000015_gene3517	2.448e-71	256.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DYT8@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3
MMS3_k127_2515586_10	1179773.BN6_31940	6.904e-25	113.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4EAE7@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	senR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_2515586_1	365528.KB891219_gene885	1.574e-118	392.0	COG0477@1|root,COG0477@2|Bacteria,2I5V9@201174|Actinobacteria,4ETNK@85013|Frankiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_254719_2	1283299.AUKG01000001_gene1672	1.395e-111	366.0	COG1809@1|root,COG1809@2|Bacteria,2IESE@201174|Actinobacteria,4CRSB@84995|Rubrobacteria	84995|Rubrobacteria	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
MMS3_k127_254719_3	469383.Cwoe_0089	7.644e-11	74.0	COG0823@1|root,COG0823@2|Bacteria,2HNKQ@201174|Actinobacteria,4CPPF@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
MMS3_k127_254719_1	1380390.JIAT01000009_gene1700	8.478e-131	437.0	COG3307@1|root,COG3307@2|Bacteria,2IDMZ@201174|Actinobacteria,4CRI9@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_254719_0	469383.Cwoe_0093	3.043e-146	479.0	COG2244@1|root,COG2244@2|Bacteria,2I9QU@201174|Actinobacteria,4CRDA@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
MMS3_k127_2593086_1	1122939.ATUD01000011_gene2272	1.228e-181	587.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CPJ2@84995|Rubrobacteria	84995|Rubrobacteria	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
MMS3_k127_2593086_3	1380390.JIAT01000013_gene180	9.193e-40	151.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
MMS3_k127_2593086_0	469383.Cwoe_1051	4.88e-212	667.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria	201174|Actinobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
MMS3_k127_2593086_2	1380390.JIAT01000009_gene1257	1.63e-82	280.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,4CQ3N@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_260677_3	1380390.JIAT01000011_gene2691	5.853e-138	443.0	COG1960@1|root,COG1960@2|Bacteria,2GVSU@201174|Actinobacteria,4CRXS@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_260677_5	1283299.AUKG01000001_gene2765	5.28e-105	349.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4CPTH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_260677_0	469383.Cwoe_1593	2.926e-284	880.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
MMS3_k127_260677_2	1380390.JIAT01000011_gene2718	8.11e-139	451.0	COG3246@1|root,COG3246@2|Bacteria,2I9EQ@201174|Actinobacteria,4CSHR@84995|Rubrobacteria	84995|Rubrobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
MMS3_k127_260677_1	469383.Cwoe_1595	1.336e-185	589.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4CU2K@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_260677_4	469383.Cwoe_1600	2.172e-107	355.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4CPAW@84995|Rubrobacteria	84995|Rubrobacteria	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
MMS3_k127_260677_6	469383.Cwoe_1601	1.345e-78	284.0	COG1309@1|root,COG1309@2|Bacteria,2IEV2@201174|Actinobacteria,4CPWP@84995|Rubrobacteria	84995|Rubrobacteria	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
MMS3_k127_2629935_2	1380390.JIAT01000010_gene4428	1.073e-189	602.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CPJH@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMS3_k127_2629935_4	469383.Cwoe_3605	4.76e-121	395.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CP9J@84995|Rubrobacteria	84995|Rubrobacteria	L	AP endonuclease family 2	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
MMS3_k127_2629935_0	929712.KI912613_gene4004	0.0	1397.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CP98@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
MMS3_k127_2629935_1	469383.Cwoe_3610	9.011e-218	681.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CPRP@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
MMS3_k127_2629935_3	469383.Cwoe_3612	3.25e-164	527.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CPWH@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_2629935_5	1283299.AUKG01000002_gene4809	1.245e-18	86.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CPHD@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
MMS3_k127_263140_4	469383.Cwoe_5885	2.072e-75	256.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CRCP@84995|Rubrobacteria	84995|Rubrobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
MMS3_k127_263140_3	1283299.AUKG01000001_gene1856	3.132e-76	262.0	2AU40@1|root,31JQJ@2|Bacteria,2HNUU@201174|Actinobacteria,4CQ3A@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_263140_0	1968.JOEV01000001_gene7536	4.219e-190	601.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	pcaF	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_263140_1	1283299.AUKG01000001_gene2021	5.923e-123	409.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CRXQ@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_263140_2	439235.Dalk_4891	1.083e-120	399.0	COG2303@1|root,COG2303@2|Bacteria,1QC41@1224|Proteobacteria,43E7D@68525|delta/epsilon subdivisions,2WZX2@28221|Deltaproteobacteria,2MN26@213118|Desulfobacterales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMS3_k127_2682792_1	469383.Cwoe_3527	2.382e-121	394.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4CPI7@84995|Rubrobacteria	84995|Rubrobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMS3_k127_2682792_7	469383.Cwoe_3525	4.012e-78	280.0	COG0617@1|root,COG0617@2|Bacteria,2HPJN@201174|Actinobacteria,4CQXB@84995|Rubrobacteria	84995|Rubrobacteria	J	Poly A polymerase head domain	-	-	-	-	-	-	-	-	-	-	-	-	PolyA_pol
MMS3_k127_2682792_12	469383.Cwoe_3524	3.996e-52	203.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CQFG@84995|Rubrobacteria	84995|Rubrobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
MMS3_k127_2682792_9	469383.Cwoe_3523	2.198e-73	256.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CQAV@84995|Rubrobacteria	84995|Rubrobacteria	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
MMS3_k127_2682792_10	469383.Cwoe_3522	5.778e-72	246.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4CQ0C@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
MMS3_k127_2682792_4	1380390.JIAT01000010_gene4527	1.538e-94	316.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4CQQG@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
MMS3_k127_2682792_14	1380390.JIAT01000010_gene4528	2.363e-19	100.0	COG0762@1|root,COG0762@2|Bacteria,2HR5Q@201174|Actinobacteria,4CT15@84995|Rubrobacteria	84995|Rubrobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
MMS3_k127_2682792_13	1283299.AUKG01000002_gene4922	7.68e-41	166.0	COG0597@1|root,COG0597@2|Bacteria,2HP4E@201174|Actinobacteria,4CQFY@84995|Rubrobacteria	84995|Rubrobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
MMS3_k127_2682792_5	469383.Cwoe_3518	1.353e-84	292.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMS3_k127_2682792_0	469383.Cwoe_3517	5.64e-126	421.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CQ0Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
MMS3_k127_2682792_8	1380390.JIAT01000010_gene4533	2.66e-77	266.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CQ46@84995|Rubrobacteria	84995|Rubrobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
MMS3_k127_2682792_2	1380390.JIAT01000010_gene4534	1.828e-116	379.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CPH9@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
MMS3_k127_2682792_6	469383.Cwoe_3514	1.421e-79	270.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CQ2J@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
MMS3_k127_2682792_3	1380390.JIAT01000010_gene4536	3.204e-102	344.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CPUS@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
MMS3_k127_2682792_11	1283299.AUKG01000002_gene4929	4.981e-64	230.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4CQ05@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
MMS3_k127_2697432_13	525909.Afer_1069	4.66e-46	177.0	2EFBW@1|root,3394U@2|Bacteria,2H758@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2697432_5	351607.Acel_0233	1.045e-110	374.0	COG3391@1|root,COG3391@2|Bacteria,2I1IX@201174|Actinobacteria,4EVVE@85013|Frankiales	2|Bacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,DUF4114,Lactonase,Phage-tail_3
MMS3_k127_2697432_1	469383.Cwoe_1723	3.717e-211	685.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CRWU@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPase (P-type)	-	-	3.6.3.8	ko:K01537,ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.23	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
MMS3_k127_2697432_2	663610.JQKO01000008_gene199	1.595e-154	518.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR56@28211|Alphaproteobacteria,3N9V6@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	haloacid dehalogenase-like hydrolase	cadA	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
MMS3_k127_2697432_14	1122939.ATUD01000001_gene328	1.416e-43	174.0	2EN03@1|root,33FN9@2|Bacteria,2HNYF@201174|Actinobacteria,4CQ7V@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
MMS3_k127_2697432_23	7955.ENSDARP00000088904	1.448e-05	57.0	KOG4441@1|root,KOG4441@2759|Eukaryota,39PFQ@33154|Opisthokonta,3BJW6@33208|Metazoa,3CUSE@33213|Bilateria,484QF@7711|Chordata,4953A@7742|Vertebrata,49U65@7898|Actinopterygii	33208|Metazoa	T	Kelch-like	KLHL24	GO:0000151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005911,GO:0005912,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016567,GO:0019538,GO:0030054,GO:0030057,GO:0031461,GO:0031463,GO:0032446,GO:0032991,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0045103,GO:0045104,GO:0045109,GO:0051865,GO:0070161,GO:0070647,GO:0071704,GO:0071840,GO:0097435,GO:1901564,GO:1902494,GO:1990234	-	ko:K10461	-	-	-	-	ko00000,ko04121	-	-	-	BACK,BTB,Kelch_1
MMS3_k127_2697432_15	1463887.KL590036_gene3621	1.567e-41	163.0	2E39M@1|root,32Y96@2|Bacteria,2IITE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2697432_9	1380390.JIAT01000010_gene3555	2.301e-62	222.0	COG3023@1|root,COG3023@2|Bacteria,2HCX7@201174|Actinobacteria,4CQYZ@84995|Rubrobacteria	84995|Rubrobacteria	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
MMS3_k127_2697432_21	1463820.JOGW01000002_gene6140	5.385e-14	83.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,HTH_IclR
MMS3_k127_2697432_22	543632.JOJL01000004_gene4102	5.616e-06	57.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	uspA4	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2697432_16	929712.KI912613_gene952	3.24e-38	147.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4CQEK@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
MMS3_k127_2697432_12	543632.JOJL01000042_gene4589	1.415e-51	194.0	COG1414@1|root,COG1414@2|Bacteria,2IBUX@201174|Actinobacteria,4DM63@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMS3_k127_2697432_10	326427.Cagg_1100	6.059e-61	220.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_2697432_11	1001240.GY21_12265	1.544e-56	215.0	COG0642@1|root,COG0642@2|Bacteria,2I2VJ@201174|Actinobacteria,4FTR6@85023|Microbacteriaceae	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_2697432_7	1283299.AUKG01000001_gene3009	9.811e-69	245.0	COG1477@1|root,COG1477@2|Bacteria,2HQ3C@201174|Actinobacteria,4CRJW@84995|Rubrobacteria	84995|Rubrobacteria	H	ApbE family	-	-	-	-	-	-	-	-	-	-	-	-	ApbE
MMS3_k127_2697432_17	1380390.JIAT01000014_gene6282	2.311e-37	154.0	COG4097@1|root,COG4097@2|Bacteria,2HPUY@201174|Actinobacteria,4CR8R@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
MMS3_k127_2697432_24	1459636.NTE_00416	0.000589	51.0	COG0484@1|root,COG1141@1|root,arCOG00349@2157|Archaea,arCOG02846@2157|Archaea,41ST0@651137|Thaumarchaeota	651137|Thaumarchaeota	CO	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,Fer4_13
MMS3_k127_2697432_4	469383.Cwoe_4711	1.459e-146	481.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_2697432_0	469383.Cwoe_4712	2.942e-279	869.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
MMS3_k127_2697432_19	1193181.BN10_680060	1.499e-30	128.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_2697432_3	1121022.ABENE_22605	4.399e-148	479.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2TVQF@28211|Alphaproteobacteria,2KID5@204458|Caulobacterales	28211|Alphaproteobacteria	S	PFAM HipA domain protein	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
MMS3_k127_2697432_20	1255043.TVNIR_0740	2.575e-20	94.0	COG1813@1|root,COG1813@2|Bacteria,1QWNX@1224|Proteobacteria,1T3Z9@1236|Gammaproteobacteria,1WZRR@135613|Chromatiales	135613|Chromatiales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMS3_k127_2697432_18	1385520.N802_06940	2.421e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,2IR68@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2697432_6	471853.Bcav_1381	1.202e-69	252.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria	201174|Actinobacteria	CG	Glycosyltransferase, MGT family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
MMS3_k127_2697432_8	591158.SSMG_00913	2.325e-63	222.0	COG0637@1|root,COG0637@2|Bacteria,2I7TC@201174|Actinobacteria	201174|Actinobacteria	H	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS3_k127_2708268_19	1283299.AUKG01000002_gene4772	1.066e-88	299.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CSHN@84995|Rubrobacteria	84995|Rubrobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_2708268_10	469383.Cwoe_3664	1.685e-123	401.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4CQ8F@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_2708268_25	469383.Cwoe_1891	7.594e-57	200.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4CQRD@84995|Rubrobacteria	84995|Rubrobacteria	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
MMS3_k127_2708268_27	1380390.JIAT01000014_gene6073	1.291e-52	194.0	2B89Y@1|root,321II@2|Bacteria,2HP5D@201174|Actinobacteria,4CQHC@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2708268_33	1380390.JIAT01000014_gene6071	1.412e-40	152.0	2A00B@1|root,30N2D@2|Bacteria,2HP1D@201174|Actinobacteria,4CQBW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2708268_8	1108045.GORHZ_117_00240	1.512e-132	427.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4GF05@85026|Gordoniaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS3_k127_2708268_2	469383.Cwoe_1896	5.432e-188	603.0	COG0438@1|root,COG0438@2|Bacteria,2H432@201174|Actinobacteria,4CR80@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2708268_24	1380390.JIAT01000014_gene6062	6.84e-63	218.0	COG0517@1|root,COG0517@2|Bacteria,2I6I8@201174|Actinobacteria,4CQHZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMS3_k127_2708268_41	1283299.AUKG01000001_gene3226	0.0009645	43.0	2BGHP@1|root,32AFX@2|Bacteria,2HPGY@201174|Actinobacteria,4CQV8@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2708268_14	1380390.JIAT01000014_gene6059	1.516e-115	379.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4CS5J@84995|Rubrobacteria	84995|Rubrobacteria	O	UbiA prenyltransferase family	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
MMS3_k127_2708268_0	1283299.AUKG01000001_gene3228	1.083e-275	859.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CP91@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
MMS3_k127_2708268_20	469383.Cwoe_1910	2.584e-80	277.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4CPBE@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C oxidase subunit II, transmembrane domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
MMS3_k127_2708268_17	1283299.AUKG01000001_gene3230	7.38e-101	335.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,4CQ29@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS3_k127_2708268_16	469383.Cwoe_4227	1.921e-101	341.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4CPYI@84995|Rubrobacteria	84995|Rubrobacteria	S	peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
MMS3_k127_2708268_15	469383.Cwoe_1912	1.617e-103	345.0	COG0671@1|root,COG0671@2|Bacteria,2HPYC@201174|Actinobacteria,4CRDJ@84995|Rubrobacteria	84995|Rubrobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
MMS3_k127_2708268_18	469383.Cwoe_1913	1.044e-100	344.0	COG0392@1|root,COG0392@2|Bacteria,2HQ3T@201174|Actinobacteria,4CRKA@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
MMS3_k127_2708268_7	469383.Cwoe_1914	5.676e-149	479.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CP86@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_2708268_31	1380390.JIAT01000014_gene6037	1.146e-47	182.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4CQVT@84995|Rubrobacteria	84995|Rubrobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
MMS3_k127_2708268_30	1380390.JIAT01000014_gene6036	7.542e-48	179.0	COG1595@1|root,COG1595@2|Bacteria,2II47@201174|Actinobacteria,4CSB0@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2708268_13	469383.Cwoe_2190	7.363e-118	401.0	COG1250@1|root,COG1250@2|Bacteria,2GPFP@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS3_k127_2708268_11	1463920.JOGB01000002_gene3261	1.98e-120	413.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2708268_1	469383.Cwoe_5268	3.359e-231	729.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CP9U@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
MMS3_k127_2708268_35	469383.Cwoe_1917	2.749e-31	130.0	COG0702@1|root,COG0702@2|Bacteria,2HQUJ@201174|Actinobacteria,4CSM6@84995|Rubrobacteria	84995|Rubrobacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
MMS3_k127_2708268_12	2074.JNYD01000011_gene147	4.019e-119	387.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria	201174|Actinobacteria	O	alkyl hydroperoxide reductase	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
MMS3_k127_2708268_28	929712.KI912613_gene4662	7.108e-51	187.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4CQAZ@84995|Rubrobacteria	84995|Rubrobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_2708268_26	469383.Cwoe_1919	9.007e-53	188.0	COG1765@1|root,COG1765@2|Bacteria,2IIKU@201174|Actinobacteria,4CQ86@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
MMS3_k127_2708268_6	1283299.AUKG01000001_gene3257	3.122e-159	512.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4CS23@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
MMS3_k127_2708268_39	1121355.KB903379_gene745	2.702e-06	50.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
MMS3_k127_2708268_23	1463879.JOHP01000002_gene1913	3.056e-65	228.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
MMS3_k127_2708268_32	1403819.BATR01000092_gene2690	4.699e-45	173.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS3_k127_2708268_40	1385517.N800_06190	4.301e-06	56.0	COG1695@1|root,COG1695@2|Bacteria,1NJSY@1224|Proteobacteria,1SG6R@1236|Gammaproteobacteria,1X6UG@135614|Xanthomonadales	135614|Xanthomonadales	K	PadR family transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
MMS3_k127_2708268_36	469383.Cwoe_1963	1.597e-30	132.0	COG1124@1|root,COG1124@2|Bacteria	2|Bacteria	EP	nickel-transporting ATPase activity	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	Asp23,MMPL
MMS3_k127_2708268_22	469383.Cwoe_1962	1.735e-67	237.0	COG1136@1|root,COG1136@2|Bacteria,2GNB3@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	hrtA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2708268_5	469383.Cwoe_1961	9.499e-160	534.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	84995|Rubrobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_2708268_34	1280390.CBQR020000133_gene3304	3.594e-37	154.0	2C5HJ@1|root,2Z812@2|Bacteria,1TQQ6@1239|Firmicutes,4HA3F@91061|Bacilli,26R9B@186822|Paenibacillaceae	91061|Bacilli	S	Tetraprenyl-beta-curcumene synthase	ytpB	-	4.2.3.130	ko:K16188	-	-	R10009	RC02994	ko00000,ko01000	-	-	-	DUF2600
MMS3_k127_2708268_29	543632.JOJL01000042_gene4589	3.712e-50	191.0	COG1414@1|root,COG1414@2|Bacteria,2IBUX@201174|Actinobacteria,4DM63@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMS3_k127_2708268_9	1048339.KB913029_gene3712	9.984e-126	421.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
MMS3_k127_2708268_4	469383.Cwoe_4652	6.259e-162	522.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4CQI2@84995|Rubrobacteria	84995|Rubrobacteria	G	Starch synthase catalytic domain	-	-	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2708268_3	68570.DC74_4354	1.437e-178	575.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	alkK	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2708268_38	688245.CtCNB1_1501	6.484e-15	77.0	COG1476@1|root,COG1476@2|Bacteria,1NPDH@1224|Proteobacteria,2WHZT@28216|Betaproteobacteria,4AK3Z@80864|Comamonadaceae	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
MMS3_k127_2708268_21	1283299.AUKG01000001_gene3100	5.307e-74	254.0	COG2406@1|root,COG2406@2|Bacteria,2HPQS@201174|Actinobacteria,4CR3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Rubrerythrin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
MMS3_k127_2709754_2	469383.Cwoe_5257	2.239e-56	201.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CPN8@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
MMS3_k127_2709754_1	469383.Cwoe_5256	8.481e-57	218.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4CQ1I@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
MMS3_k127_2709754_4	1283299.AUKG01000003_gene563	1.378e-11	71.0	2AX2K@1|root,31P0X@2|Bacteria,2HRH6@201174|Actinobacteria,4CTGV@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2709754_0	1283299.AUKG01000003_gene564	5.844e-135	444.0	COG2508@1|root,COG2508@2|Bacteria,2HJJI@201174|Actinobacteria,4CPT6@84995|Rubrobacteria	84995|Rubrobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
MMS3_k127_2709754_3	469383.Cwoe_4717	1.531e-24	109.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4CQKG@84995|Rubrobacteria	84995|Rubrobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
MMS3_k127_2746908_0	711393.AYRX01000079_gene5324	1.075e-86	301.0	COG2855@1|root,COG2855@2|Bacteria,2GS6E@201174|Actinobacteria	201174|Actinobacteria	P	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
MMS3_k127_2746908_1	469383.Cwoe_4857	1.672e-81	291.0	COG0583@1|root,COG0583@2|Bacteria,2GMES@201174|Actinobacteria,4CQ91@84995|Rubrobacteria	84995|Rubrobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_2746908_2	1108045.GORHZ_055_00200	1.975e-47	177.0	COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2816680_2	469383.Cwoe_4730	4.187e-13	73.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2816680_1	469383.Cwoe_1562	4.145e-21	104.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
MMS3_k127_2816680_0	512565.AMIS_56130	8.969e-49	188.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4DD8B@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
MMS3_k127_2835435_11	1380390.JIAT01000009_gene785	4.854e-28	119.0	COG3415@1|root,COG3415@2|Bacteria,2HPB2@201174|Actinobacteria,4CQPA@84995|Rubrobacteria	84995|Rubrobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
MMS3_k127_2835435_8	469383.Cwoe_5278	7.301e-39	158.0	COG3832@1|root,COG3832@2|Bacteria,2HQWE@201174|Actinobacteria,4CSPB@84995|Rubrobacteria	84995|Rubrobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_2835435_4	469383.Cwoe_5277	1.058e-87	303.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4CP7S@84995|Rubrobacteria	84995|Rubrobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
MMS3_k127_2835435_6	649831.L083_2758	1.091e-62	239.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4DACE@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
MMS3_k127_2835435_9	1380390.JIAT01000009_gene773	9.685e-36	141.0	2AWFM@1|root,31NBV@2|Bacteria,2HQY5@201174|Actinobacteria,4CSQN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2835435_7	469383.Cwoe_5271	5.042e-60	222.0	COG1309@1|root,COG1309@2|Bacteria,2HQ9V@201174|Actinobacteria,4CRTR@84995|Rubrobacteria	84995|Rubrobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
MMS3_k127_2835435_12	1380390.JIAT01000009_gene751	3.535e-26	111.0	COG2331@1|root,COG2331@2|Bacteria,2HN5H@201174|Actinobacteria,4CQJS@84995|Rubrobacteria	84995|Rubrobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2835435_1	1172188.KB911822_gene763	2.078e-146	486.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,4FJ6N@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Lipase_GDSL_2
MMS3_k127_2835435_2	1380390.JIAT01000009_gene750	8.996e-106	355.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CPSE@84995|Rubrobacteria	84995|Rubrobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
MMS3_k127_2835435_5	1380390.JIAT01000009_gene748	3.028e-84	289.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CQ57@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
MMS3_k127_2835435_0	1380390.JIAT01000009_gene746	6.524e-231	724.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CQ79@84995|Rubrobacteria	84995|Rubrobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
MMS3_k127_2835435_3	469383.Cwoe_5258	6.452e-99	334.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CPR6@84995|Rubrobacteria	84995|Rubrobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
MMS3_k127_2835435_10	1283299.AUKG01000003_gene560	1.193e-31	134.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CPN8@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
MMS3_k127_284384_7	1122939.ATUD01000010_gene2952	3.135e-29	127.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4CT94@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_284384_2	880073.Calab_1405	3.754e-93	319.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS3_k127_284384_3	469383.Cwoe_5355	2.204e-62	217.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CSRN@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_284384_0	469383.Cwoe_2624	1.314e-154	498.0	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria,4CPUR@84995|Rubrobacteria	84995|Rubrobacteria	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_284384_8	525909.Afer_0056	3.371e-28	127.0	COG1813@1|root,COG1813@2|Bacteria	2|Bacteria	K	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
MMS3_k127_284384_6	525909.Afer_0055	1.609e-43	166.0	2DMWY@1|root,32U6G@2|Bacteria,2ISFN@201174|Actinobacteria,4CNVD@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_284384_9	591167.Sfla_1885	1.205e-13	80.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
MMS3_k127_284384_5	1146883.BLASA_0946	1.026e-43	170.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EVFA@85013|Frankiales	201174|Actinobacteria	K	Response regulator receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
MMS3_k127_284384_4	469383.Cwoe_2525	8.963e-44	170.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_284384_1	469383.Cwoe_5353	8.479e-115	380.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
MMS3_k127_285234_11	215803.DB30_8836	4.279e-15	87.0	COG0515@1|root,COG0775@1|root,COG0515@2|Bacteria,COG0775@2|Bacteria,1PEJP@1224|Proteobacteria,433ZI@68525|delta/epsilon subdivisions,2X487@28221|Deltaproteobacteria,2YYGN@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase,TIR_2
MMS3_k127_285234_9	469383.Cwoe_3273	1.296e-41	165.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CQI8@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
MMS3_k127_285234_7	1380347.JNII01000009_gene2079	5.509e-55	209.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria,4EVQ7@85013|Frankiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
MMS3_k127_285234_4	469383.Cwoe_3564	1.049e-99	334.0	COG3662@1|root,COG3662@2|Bacteria,2II6C@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
MMS3_k127_285234_1	1713.JOFV01000007_gene2867	4.097e-188	614.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4F289@85016|Cellulomonadaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_285234_2	1380390.JIAT01000013_gene315	2.903e-175	560.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4CRNS@84995|Rubrobacteria	84995|Rubrobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_285234_5	1122939.ATUD01000002_gene1224	2.118e-92	315.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CRIE@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
MMS3_k127_285234_0	1121920.AUAU01000033_gene2756	1.274e-196	633.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
MMS3_k127_285234_6	469383.Cwoe_3622	2.754e-88	299.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CQ6T@84995|Rubrobacteria	84995|Rubrobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
MMS3_k127_285234_10	469383.Cwoe_3620	4.18e-23	106.0	COG0291@1|root,COG0291@2|Bacteria,2HPDV@201174|Actinobacteria,4CQRX@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
MMS3_k127_285234_8	1283299.AUKG01000002_gene4803	5.595e-52	190.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4CQE4@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
MMS3_k127_285234_3	1283299.AUKG01000002_gene4805	1.072e-160	517.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CPUG@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
MMS3_k127_2860333_8	1283299.AUKG01000002_gene4050	2.344e-90	320.0	COG0226@1|root,COG0226@2|Bacteria,2GJXD@201174|Actinobacteria,4CPNN@84995|Rubrobacteria	201174|Actinobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMS3_k127_2860333_25	1380390.JIAT01000001_gene5002	1.592e-36	143.0	COG0745@1|root,COG0745@2|Bacteria,2HRF4@201174|Actinobacteria,4CTDQ@84995|Rubrobacteria	84995|Rubrobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
MMS3_k127_2860333_13	1283299.AUKG01000002_gene4064	3.659e-75	259.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4CQ5I@84995|Rubrobacteria	84995|Rubrobacteria	P	Protein of unknown function DUF47	-	-	-	-	-	-	-	-	-	-	-	-	PhoU_div
MMS3_k127_2860333_6	469383.Cwoe_4769	1.567e-98	347.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CPBX@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMS3_k127_2860333_5	1283299.AUKG01000002_gene4056	3.753e-102	364.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CPG4@84995|Rubrobacteria	84995|Rubrobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
MMS3_k127_2860333_7	469383.Cwoe_4767	2.625e-98	331.0	COG0573@1|root,COG0573@2|Bacteria,2ISS5@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS3_k127_2860333_17	1380390.JIAT01000001_gene5011	4.083e-62	223.0	COG0226@1|root,COG0226@2|Bacteria,2HNRT@201174|Actinobacteria,4CPZE@84995|Rubrobacteria	84995|Rubrobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMS3_k127_2860333_0	469383.Cwoe_4762	2.1e-268	848.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CRP4@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
MMS3_k127_2860333_16	929712.KI912613_gene4595	3.175e-65	237.0	2AXMN@1|root,31PMY@2|Bacteria,2HRZP@201174|Actinobacteria,4CRJJ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2860333_15	1283299.AUKG01000003_gene462	4.237e-69	263.0	COG0823@1|root,COG0823@2|Bacteria,2HR2G@201174|Actinobacteria,4CSXG@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2860333_1	1283299.AUKG01000003_gene464	2.177e-178	617.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,Kelch_4,fn3
MMS3_k127_2860333_30	929712.KI912613_gene4599	1.279e-23	116.0	COG0226@1|root,COG0226@2|Bacteria,2HREN@201174|Actinobacteria,4CTD4@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2860333_14	929712.KI912613_gene2544	1.405e-74	271.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CRCH@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
MMS3_k127_2860333_10	1283299.AUKG01000004_gene1114	1.394e-88	305.0	COG0438@1|root,COG0438@2|Bacteria,2GJI0@201174|Actinobacteria,4CRJA@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2860333_33	1206730.BAGA01000184_gene3039	4.415e-14	85.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4FU95@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_2860333_31	42256.RradSPS_2328	7.531e-17	92.0	COG4424@1|root,COG4424@2|Bacteria,2HETZ@201174|Actinobacteria	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
MMS3_k127_2860333_18	63737.Npun_R1061	5.925e-59	220.0	COG0438@1|root,COG0438@2|Bacteria,1G3JN@1117|Cyanobacteria,1HRCH@1161|Nostocales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2860333_22	1151122.AQYD01000004_gene2793	3.135e-42	177.0	COG0438@1|root,COG0438@2|Bacteria,2IBSQ@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2860333_9	1280390.CBQR020000171_gene4552	2.942e-89	307.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
MMS3_k127_2860333_34	46234.ANA_C13153	7.285e-13	82.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1G0TN@1117|Cyanobacteria,1HK8X@1161|Nostocales	1117|Cyanobacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA,Wzz
MMS3_k127_2860333_3	1380347.JNII01000006_gene1097	3.121e-126	427.0	COG1132@1|root,COG1132@2|Bacteria,2HXAQ@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter ATP-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
MMS3_k127_2860333_20	649638.Trad_2723	1.271e-48	188.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
MMS3_k127_2860333_23	111780.Sta7437_1420	2.681e-38	156.0	COG4424@1|root,COG4424@2|Bacteria,1G29K@1117|Cyanobacteria,3VJFW@52604|Pleurocapsales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
MMS3_k127_2860333_21	1056820.KB900660_gene3588	1.268e-42	169.0	COG4424@1|root,COG4424@2|Bacteria,1RGI6@1224|Proteobacteria,1S85X@1236|Gammaproteobacteria,2PPGM@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
MMS3_k127_2860333_19	1541065.JRFE01000003_gene5376	1.315e-49	190.0	COG4424@1|root,COG4424@2|Bacteria,1G29K@1117|Cyanobacteria,3VJFW@52604|Pleurocapsales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
MMS3_k127_2860333_12	864702.OsccyDRAFT_4936	2.118e-78	276.0	COG0438@1|root,COG0438@2|Bacteria,1G2XD@1117|Cyanobacteria,1HEBD@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2860333_2	28072.Nos7524_0436	2.708e-131	436.0	COG0438@1|root,COG0438@2|Bacteria,1GJ8Y@1117|Cyanobacteria,1HR1B@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
MMS3_k127_2860333_35	477974.Daud_1692	1.359e-05	57.0	COG0438@1|root,COG0438@2|Bacteria,1VN77@1239|Firmicutes	1239|Firmicutes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_2860333_24	56107.Cylst_4701	1.503e-36	154.0	COG0438@1|root,COG0438@2|Bacteria,1G6HW@1117|Cyanobacteria,1HMQ8@1161|Nostocales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2860333_27	106370.Francci3_4064	2.98e-32	135.0	COG3963@1|root,COG3963@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
MMS3_k127_2860333_32	266117.Rxyl_2683	2.175e-15	88.0	COG4424@1|root,COG4424@2|Bacteria,2HETZ@201174|Actinobacteria	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
MMS3_k127_2860333_26	1206729.BAFZ01000002_gene220	4.822e-34	137.0	COG0438@1|root,COG0438@2|Bacteria,2IEM5@201174|Actinobacteria,4FVNJ@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2879684_11	926554.KI912668_gene5156	8.393e-12	78.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1,MFS_3
MMS3_k127_2879684_2	1380390.JIAT01000011_gene2651	5.816e-119	399.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4CR7M@84995|Rubrobacteria	84995|Rubrobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMS3_k127_2879684_13	1232437.KL662061_gene4181	6.45e-06	52.0	COG0745@1|root,COG0789@1|root,COG0745@2|Bacteria,COG0789@2|Bacteria,1RD9E@1224|Proteobacteria,42PTZ@68525|delta/epsilon subdivisions,2WKZI@28221|Deltaproteobacteria,2MHNV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
MMS3_k127_2879684_6	1123024.AUII01000004_gene1505	4.009e-47	170.0	COG3549@1|root,COG3549@2|Bacteria,2IT6K@201174|Actinobacteria	201174|Actinobacteria	S	Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
MMS3_k127_2879684_8	1123024.AUII01000004_gene1506	8.11e-45	166.0	COG3093@1|root,COG3093@2|Bacteria,2IR2S@201174|Actinobacteria,4EC90@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
MMS3_k127_2879684_3	1283299.AUKG01000002_gene5315	2.437e-105	350.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CPFG@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
MMS3_k127_2879684_5	929712.KI912613_gene3469	6.519e-79	271.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CQ7R@84995|Rubrobacteria	84995|Rubrobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
MMS3_k127_2879684_0	469383.Cwoe_3076	0.0	1021.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CPJ0@84995|Rubrobacteria	84995|Rubrobacteria	HI	1-deoxy-D-xylulose-5-phosphate synthase	-	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
MMS3_k127_2879684_1	1380390.JIAT01000003_gene5435	1.615e-122	400.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria,4CP7H@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS3_k127_2879684_10	1380390.JIAT01000003_gene5434	3.049e-13	72.0	2AX4E@1|root,31P2S@2|Bacteria,2HRIM@201174|Actinobacteria,4CTJE@84995|Rubrobacteria	84995|Rubrobacteria	S	Exonuclease VII small subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2879684_7	1380390.JIAT01000003_gene5433	3.913e-45	168.0	COG0781@1|root,COG0781@2|Bacteria,2HP01@201174|Actinobacteria,4CQ9N@84995|Rubrobacteria	84995|Rubrobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
MMS3_k127_2879684_4	1380390.JIAT01000003_gene5432	5.099e-89	297.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CPH7@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
MMS3_k127_2879684_9	526227.Mesil_0486	2.248e-25	121.0	COG1961@1|root,COG1961@2|Bacteria,1WM3J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Recombinase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
MMS3_k127_2879684_12	469383.Cwoe_4036	6.482e-08	59.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
MMS3_k127_2880319_0	1380390.JIAT01000010_gene4872	3.433e-122	396.0	COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4CPST@84995|Rubrobacteria	84995|Rubrobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_2880319_2	525904.Tter_0136	3.403e-27	130.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
MMS3_k127_2880319_3	290397.Adeh_0590	2.677e-16	94.0	COG3391@1|root,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria	1224|Proteobacteria	M	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Abhydrolase_3,Cadherin-like,Cadherin_3,TIG,VCBS
MMS3_k127_2880319_1	1380390.JIAT01000010_gene4081	4.978e-92	312.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4CSBE@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_2934843_16	469383.Cwoe_1668	7.342e-62	220.0	COG2820@1|root,COG2820@2|Bacteria,2I4KP@201174|Actinobacteria,4CQU2@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylase superfamily	-	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_2934843_3	469383.Cwoe_1670	1.065e-141	460.0	COG0789@1|root,COG2114@1|root,COG0789@2|Bacteria,COG2114@2|Bacteria,2ICT6@201174|Actinobacteria,4CR4V@84995|Rubrobacteria	84995|Rubrobacteria	KT	Adenylate cyclase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	Ad_Cy_reg,Guanylate_cyc,MerR_1
MMS3_k127_2934843_12	469383.Cwoe_1671	3.138e-91	313.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CQ9P@84995|Rubrobacteria	84995|Rubrobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
MMS3_k127_2934843_14	1380390.JIAT01000011_gene2837	2.074e-76	261.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
MMS3_k127_2934843_0	1380390.JIAT01000011_gene2838	0.0	1011.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CPFJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_2934843_10	469383.Cwoe_1674	8.804e-96	323.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CPWZ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
MMS3_k127_2934843_19	469383.Cwoe_1675	4.984e-54	198.0	COG1539@1|root,COG1539@2|Bacteria,2HQ0Z@201174|Actinobacteria,4CRGX@84995|Rubrobacteria	84995|Rubrobacteria	H	Dihydroneopterin aldolase	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
MMS3_k127_2934843_21	929712.KI912613_gene4797	4.597e-49	188.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4CQM0@84995|Rubrobacteria	84995|Rubrobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
MMS3_k127_2934843_22	1283299.AUKG01000001_gene3054	7.191e-49	186.0	COG0791@1|root,COG0791@2|Bacteria,2HQTI@201174|Actinobacteria,4CSIU@84995|Rubrobacteria	84995|Rubrobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2934843_8	1283299.AUKG01000001_gene3055	4.698e-110	361.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4CPNS@84995|Rubrobacteria	84995|Rubrobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
MMS3_k127_2934843_24	1283299.AUKG01000001_gene3056	2.872e-23	103.0	2E3Z4@1|root,32YW2@2|Bacteria,2IQZ7@201174|Actinobacteria,4CQPN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2934843_15	1283299.AUKG01000001_gene3062	1.366e-73	252.0	arCOG04740@1|root,31PZA@2|Bacteria,2GP15@201174|Actinobacteria,4CQ51@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2934843_7	469383.Cwoe_1785	2.067e-110	364.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMS3_k127_2934843_11	1380390.JIAT01000013_gene85	1.137e-92	318.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CQIT@84995|Rubrobacteria	84995|Rubrobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
MMS3_k127_2934843_2	469383.Cwoe_1791	1.861e-154	499.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4CQ2U@84995|Rubrobacteria	84995|Rubrobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
MMS3_k127_2934843_1	469383.Cwoe_1792	8.588e-164	524.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CPTX@84995|Rubrobacteria	84995|Rubrobacteria	E	Homoserine dehydrogenase	-	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
MMS3_k127_2934843_4	1380390.JIAT01000014_gene6225	1.158e-140	457.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4CPKK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_2934843_6	1283299.AUKG01000001_gene3074	2.292e-123	401.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CQEJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
MMS3_k127_2934843_9	469383.Cwoe_1796	1.568e-107	355.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CRIE@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
MMS3_k127_2934843_17	1283299.AUKG01000001_gene3077	3.533e-59	213.0	COG1716@1|root,COG1716@2|Bacteria,2HR0I@201174|Actinobacteria,4CSUC@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMS3_k127_2934843_20	1283299.AUKG01000001_gene3079	8.963e-51	186.0	29VB2@1|root,30GR7@2|Bacteria,2HY8H@201174|Actinobacteria,4CQFR@84995|Rubrobacteria	84995|Rubrobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_2934843_23	1283299.AUKG01000001_gene3080	2.241e-27	124.0	2AUMD@1|root,31KA7@2|Bacteria,2HP75@201174|Actinobacteria,4CQJE@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2934843_5	1380390.JIAT01000014_gene6213	2.556e-126	426.0	COG0768@1|root,COG0768@2|Bacteria,2GJAM@201174|Actinobacteria,4CRTA@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	MecA_N,PBP_dimer,Transpeptidase
MMS3_k127_2934843_13	469383.Cwoe_1802	9.749e-85	293.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CP5Z@84995|Rubrobacteria	84995|Rubrobacteria	O	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
MMS3_k127_2937571_1	1380390.JIAT01000017_gene5331	5.345e-94	325.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4CQY6@84995|Rubrobacteria	84995|Rubrobacteria	G	Galactokinase galactose-binding signature	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
MMS3_k127_2937571_2	1122939.ATUD01000010_gene2832	7.487e-90	306.0	COG0300@1|root,COG0300@2|Bacteria,2HF4X@201174|Actinobacteria,4CR1X@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2937571_0	235985.BBPN01000009_gene3799	4.924e-134	433.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,2NGJZ@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2937571_3	1380390.JIAT01000009_gene2251	1.313e-22	97.0	29YTX@1|root,30KQ8@2|Bacteria,2HRNA@201174|Actinobacteria,4CTQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
MMS3_k127_2959723_10	882083.SacmaDRAFT_2273	2.255e-30	135.0	2EZP7@1|root,33SU8@2|Bacteria,2H4B7@201174|Actinobacteria,4EAP8@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2959723_8	469383.Cwoe_5911	2.63e-38	152.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CQAY@84995|Rubrobacteria	84995|Rubrobacteria	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
MMS3_k127_2959723_4	452652.KSE_30020	4.261e-74	256.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,2M1CI@2063|Kitasatospora	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_2959723_3	208439.AJAP_11230	5.002e-82	281.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4E26W@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2959723_6	1173026.Glo7428_2690	1.712e-70	261.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2959723_5	935548.KI912159_gene351	1.193e-73	269.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,2TU3J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
MMS3_k127_2959723_7	235985.BBPN01000002_gene5137	9.604e-58	220.0	COG4677@1|root,COG4677@2|Bacteria,2I5JZ@201174|Actinobacteria,2NKFF@228398|Streptacidiphilus	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
MMS3_k127_2959723_14	1380390.JIAT01000009_gene1648	1.251e-10	72.0	COG3637@1|root,COG4655@1|root,COG3637@2|Bacteria,COG4655@2|Bacteria,2I7MH@201174|Actinobacteria	201174|Actinobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2959723_0	1306174.JODP01000003_gene1866	3.888e-134	451.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
MMS3_k127_2959723_2	1463879.JOHP01000015_gene4482	2.316e-94	330.0	COG0477@1|root,COG2814@2|Bacteria,2I8TX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2959723_11	266117.Rxyl_0884	1.224e-26	114.0	COG0662@1|root,COG0662@2|Bacteria,2I5KR@201174|Actinobacteria,4CTK8@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_2959723_16	1449069.JMLO01000009_gene4141	0.0005274	48.0	295ZC@1|root,2ZTA4@2|Bacteria,2GUHR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2959723_9	1117318.PRUB_18585	4.711e-33	136.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
MMS3_k127_2959723_15	1158614.I592_03400	0.0001233	46.0	29K4K@1|root,30720@2|Bacteria,1U0VY@1239|Firmicutes,4IABX@91061|Bacilli,4B5CG@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2959723_1	469383.Cwoe_0202	5.978e-117	394.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CPQ8@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2959723_12	452637.Oter_3065	1.192e-16	95.0	COG0823@1|root,COG3210@1|root,COG5276@1|root,COG0823@2|Bacteria,COG3210@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	U	domain, Protein	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3739,Germane,Gmad1,Haemagg_act,LVIVD
MMS3_k127_2975517_10	1380390.JIAT01000011_gene2794	4.815e-37	147.0	COG0715@1|root,COG0715@2|Bacteria,2HFU1@201174|Actinobacteria,4CQ47@84995|Rubrobacteria	84995|Rubrobacteria	P	NMT1/THI5 like	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
MMS3_k127_2975517_6	1380390.JIAT01000011_gene2795	2.632e-71	251.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4CQ5D@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
MMS3_k127_2975517_5	469383.Cwoe_1644	2.145e-87	297.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4CPZ6@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
MMS3_k127_2975517_2	1283299.AUKG01000001_gene2882	4.217e-210	663.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CPGF@84995|Rubrobacteria	84995|Rubrobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
MMS3_k127_2975517_3	1380390.JIAT01000011_gene2800	8.983e-152	485.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4CPXK@84995|Rubrobacteria	84995|Rubrobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
MMS3_k127_2975517_7	469383.Cwoe_1652	2.172e-55	212.0	2B0SC@1|root,31T4Q@2|Bacteria,2HQ8T@201174|Actinobacteria,4CRSP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2975517_4	1283299.AUKG01000001_gene2891	1.204e-104	362.0	COG5017@1|root,COG5017@2|Bacteria,2HPVP@201174|Actinobacteria,4CRAA@84995|Rubrobacteria	84995|Rubrobacteria	S	D-glucuronyl C5-epimerase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	C5-epim_C
MMS3_k127_2975517_12	1283299.AUKG01000001_gene2896	3.288e-13	76.0	2BG9U@1|root,32A77@2|Bacteria,2HPFU@201174|Actinobacteria,4CQUB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2975517_1	469383.Cwoe_1659	6.118e-220	689.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CRMB@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2975517_0	1380390.JIAT01000011_gene2819	0.0	1012.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2GJ50@201174|Actinobacteria,4CPBM@84995|Rubrobacteria	84995|Rubrobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1
MMS3_k127_2975517_8	1380390.JIAT01000011_gene2828	4.41e-40	168.0	2AUJS@1|root,31K8C@2|Bacteria,2HP69@201174|Actinobacteria,4CQI1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2975517_11	469383.Cwoe_1667	1.974e-27	119.0	2904D@1|root,2ZMUB@2|Bacteria,2H0MU@201174|Actinobacteria,4CSUN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2975517_13	469383.Cwoe_1668	7.628e-06	50.0	COG2820@1|root,COG2820@2|Bacteria,2I4KP@201174|Actinobacteria,4CQU2@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylase superfamily	-	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_2997354_29	1120792.JAFV01000001_gene1961	1.5e-08	60.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,2UI6M@28211|Alphaproteobacteria,370ZT@31993|Methylocystaceae	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMS3_k127_2997354_5	118168.MC7420_7619	8.758e-156	529.0	COG5635@1|root,COG5635@2|Bacteria,1G3GI@1117|Cyanobacteria,1H8II@1150|Oscillatoriales	2|Bacteria	CT	Ntpase (Nacht family)	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NACHT,TIR_2
MMS3_k127_2997354_12	1380390.JIAT01000011_gene2272	5.686e-107	354.0	COG0788@1|root,COG0788@2|Bacteria,2GM0G@201174|Actinobacteria,4CR0G@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	-	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
MMS3_k127_2997354_23	1380390.JIAT01000009_gene1827	5.235e-34	143.0	2AW9W@1|root,31N5B@2|Bacteria,2HQT5@201174|Actinobacteria,4CSHX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2997354_20	469383.Cwoe_5921	1.312e-68	246.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CP82@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
MMS3_k127_2997354_24	1283299.AUKG01000001_gene1799	9.41e-34	136.0	2AWH1@1|root,31NDH@2|Bacteria,2HQZP@201174|Actinobacteria,4CST3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2997354_15	469383.Cwoe_5924	4.069e-102	353.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CQGP@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	-	-	-	-	-	-	-	-	-	-	polyprenyl_synt
MMS3_k127_2997354_16	1380390.JIAT01000009_gene1822	6.455e-94	314.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CSAX@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMS3_k127_2997354_14	1380390.JIAT01000009_gene1821	1.476e-105	347.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
MMS3_k127_2997354_6	469383.Cwoe_5927	4.709e-128	413.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CQ40@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
MMS3_k127_2997354_17	1380390.JIAT01000009_gene1819	2.286e-85	288.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria,4CQW0@84995|Rubrobacteria	84995|Rubrobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
MMS3_k127_2997354_25	469383.Cwoe_5929	2.714e-32	134.0	2AWJ7@1|root,31NFU@2|Bacteria,2HR1C@201174|Actinobacteria,4CSVI@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2997354_1	469383.Cwoe_5930	6.272e-199	629.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4CPG9@84995|Rubrobacteria	84995|Rubrobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_2997354_7	469383.Cwoe_5932	2.976e-127	415.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4CPCJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
MMS3_k127_2997354_10	1283299.AUKG01000001_gene1785	7.758e-109	372.0	COG1668@1|root,COG1668@2|Bacteria,2HNDN@201174|Actinobacteria,4CP6Y@84995|Rubrobacteria	84995|Rubrobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_2997354_19	469383.Cwoe_5934	4.728e-80	274.0	COG1131@1|root,COG1131@2|Bacteria,2HPPS@201174|Actinobacteria,4CR2G@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_2997354_8	1380390.JIAT01000009_gene1811	1.263e-125	416.0	COG0628@1|root,COG0628@2|Bacteria,2HGG6@201174|Actinobacteria,4CQ8P@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMS3_k127_2997354_9	469383.Cwoe_5935	2.285e-123	404.0	COG1692@1|root,COG1692@2|Bacteria,2IG59@201174|Actinobacteria,4CQ4Z@84995|Rubrobacteria	84995|Rubrobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
MMS3_k127_2997354_4	469383.Cwoe_5936	4.433e-171	562.0	2AU3I@1|root,31JPZ@2|Bacteria,2H277@201174|Actinobacteria,4CQ2S@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2997354_2	1380390.JIAT01000009_gene1806	5.22e-180	580.0	COG1524@1|root,COG1524@2|Bacteria,2HNGC@201174|Actinobacteria,4CPCH@84995|Rubrobacteria	84995|Rubrobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
MMS3_k127_2997354_3	469383.Cwoe_5940	5.636e-179	573.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CPBA@84995|Rubrobacteria	84995|Rubrobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
MMS3_k127_2997354_13	1380390.JIAT01000009_gene1803	7.236e-107	356.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4CPJD@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
MMS3_k127_2997354_18	1380390.JIAT01000009_gene1802	1.446e-82	278.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CQ04@84995|Rubrobacteria	84995|Rubrobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
MMS3_k127_2997354_22	469383.Cwoe_5937	3.734e-37	149.0	COG2246@1|root,COG2246@2|Bacteria,2HR1U@201174|Actinobacteria,4CSWB@84995|Rubrobacteria	84995|Rubrobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
MMS3_k127_2997354_21	1283299.AUKG01000003_gene438	1.057e-53	199.0	COG0791@1|root,COG0791@2|Bacteria,2HPJH@201174|Actinobacteria,4CQX1@84995|Rubrobacteria	84995|Rubrobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2997354_31	1380390.JIAT01000012_gene3188	0.0001511	55.0	COG2706@1|root,COG3291@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,2HRFM@201174|Actinobacteria,4CTEG@84995|Rubrobacteria	84995|Rubrobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,PKD
MMS3_k127_2997354_27	1283299.AUKG01000003_gene339	1.342e-20	97.0	2EDIK@1|root,337EH@2|Bacteria,2HRCT@201174|Actinobacteria,4CTAF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2997354_0	1380390.JIAT01000010_gene3508	0.0	1334.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
MMS3_k127_2997354_28	469383.Cwoe_4250	4.958e-17	94.0	290AJ@1|root,2ZN05@2|Bacteria,2HRSY@201174|Actinobacteria,4CTW7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2997354_11	469383.Cwoe_4251	4.297e-107	361.0	COG0389@1|root,COG0389@2|Bacteria,2HPPZ@201174|Actinobacteria,4CR2N@84995|Rubrobacteria	84995|Rubrobacteria	L	impB/mucB/samB family	-	-	-	-	-	-	-	-	-	-	-	-	IMS
MMS3_k127_2997354_30	1283299.AUKG01000002_gene5211	1.994e-06	54.0	2B6MD@1|root,31ZJU@2|Bacteria,2HRBX@201174|Actinobacteria,4CT9A@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_300602_6	469383.Cwoe_1759	1.468e-23	111.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_int_SAM_4,Phage_integrase
MMS3_k127_300602_8	1304875.JAFZ01000004_gene476	0.0003676	45.0	2DD8T@1|root,2ZH33@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_300602_2	1223523.H340_05319	5.033e-82	284.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS3_k127_300602_3	177437.HRM2_33390	2.288e-66	243.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria,2MHYS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
MMS3_k127_300602_0	1038869.AXAN01000009_gene4705	1.344e-225	716.0	COG0492@1|root,COG0492@2|Bacteria,1MVX2@1224|Proteobacteria,2VM3V@28216|Betaproteobacteria,1K4AE@119060|Burkholderiaceae	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
MMS3_k127_300602_7	399795.CtesDRAFT_PD4686	2.93e-19	92.0	COG0346@1|root,COG0346@2|Bacteria,1RABQ@1224|Proteobacteria,2VS4J@28216|Betaproteobacteria,4AHTQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase bleomycin resistance	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_300602_1	469383.Cwoe_2927	1.532e-215	678.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPIZ@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_300602_4	1380390.JIAT01000009_gene1961	4.087e-65	236.0	COG2385@1|root,COG2385@2|Bacteria,2ID9T@201174|Actinobacteria,4CPMQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
MMS3_k127_300602_5	1122939.ATUD01000006_gene1658	1.047e-24	105.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4CQ1C@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
MMS3_k127_305579_7	1463909.KL585962_gene4709	4.847e-09	57.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_305579_1	1380390.JIAT01000013_gene217	7.311e-128	421.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4CRM3@84995|Rubrobacteria	84995|Rubrobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_305579_5	469383.Cwoe_2995	5.642e-61	219.0	COG0566@1|root,COG0566@2|Bacteria,2GJ7P@201174|Actinobacteria	201174|Actinobacteria	J	SpoU rRNA Methylase family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
MMS3_k127_305579_0	469383.Cwoe_0102	1.824e-133	430.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4CU6B@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMS3_k127_305579_4	1283299.AUKG01000001_gene1644	7.059e-83	287.0	COG4221@1|root,COG4221@2|Bacteria,2GP17@201174|Actinobacteria,4CPA8@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_305579_2	469383.Cwoe_0100	4.335e-110	363.0	COG2267@1|root,COG2267@2|Bacteria,2I6HT@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_305579_8	1283299.AUKG01000001_gene3177	0.0009866	50.0	2A2FM@1|root,30QSR@2|Bacteria,2HRCN@201174|Actinobacteria,4CTA4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_305579_3	1380390.JIAT01000009_gene1683	3.172e-85	286.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CQ5U@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
MMS3_k127_305579_6	469383.Cwoe_0096	3.579e-24	105.0	COG1215@1|root,COG1215@2|Bacteria,2GXGY@201174|Actinobacteria,4CS4U@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
MMS3_k127_3128779_4	1283299.AUKG01000006_gene807	3.17e-20	96.0	COG0183@1|root,COG1024@1|root,COG0183@2|Bacteria,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	2.3.1.9,4.2.1.149	ko:K00626,ko:K08299	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177,R10675	RC00004,RC00326,RC01095	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ECH_1,Polyketide_cyc2
MMS3_k127_3128779_2	1283299.AUKG01000002_gene5008	2.883e-63	229.0	COG2220@1|root,COG2220@2|Bacteria,2GN98@201174|Actinobacteria,4CSJ8@84995|Rubrobacteria	84995|Rubrobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMS3_k127_3128779_0	1380390.JIAT01000011_gene2343	1.092e-267	839.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4CRNQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
MMS3_k127_3128779_3	1380390.JIAT01000011_gene2337	9.11e-45	168.0	COG4803@1|root,COG4803@2|Bacteria,2IQV0@201174|Actinobacteria,4CTQN@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
MMS3_k127_3128779_5	555793.WSK_3724	8.656e-20	98.0	COG0671@1|root,COG0671@2|Bacteria,1RDK3@1224|Proteobacteria,2U7BJ@28211|Alphaproteobacteria,2K70Y@204457|Sphingomonadales	204457|Sphingomonadales	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
MMS3_k127_3128779_1	1048339.KB913029_gene1556	1.145e-102	339.0	COG0596@1|root,COG0596@2|Bacteria,2I3PB@201174|Actinobacteria,4EXHN@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
MMS3_k127_3128779_7	1116369.KB890024_gene3111	1.379e-07	59.0	2EE1U@1|root,337WK@2|Bacteria,1NXPV@1224|Proteobacteria,2USZ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
MMS3_k127_3128779_6	106370.Francci3_0534	6.782e-15	85.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4ESZR@85013|Frankiales	201174|Actinobacteria	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
MMS3_k127_3159424_27	1380390.JIAT01000009_gene1158	7.315e-55	196.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4CQ7H@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMS3_k127_3159424_3	469383.Cwoe_4755	6.627e-215	675.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CPS1@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3159424_30	1283299.AUKG01000002_gene4198	3.388e-37	147.0	COG2332@1|root,COG2332@2|Bacteria,2HP5E@201174|Actinobacteria,4CQHD@84995|Rubrobacteria	84995|Rubrobacteria	O	CcmE	-	-	-	-	-	-	-	-	-	-	-	-	CcmE
MMS3_k127_3159424_1	469383.Cwoe_4478	9.927e-257	815.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria,4CRCE@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
MMS3_k127_3159424_33	1283299.AUKG01000002_gene4201	5.807e-30	120.0	COG1314@1|root,COG1314@2|Bacteria,2HP6M@201174|Actinobacteria,4CQIR@84995|Rubrobacteria	84995|Rubrobacteria	U	Preprotein translocase SecG subunit	-	-	-	-	-	-	-	-	-	-	-	-	SecG
MMS3_k127_3159424_17	929712.KI912613_gene737	3.134e-96	346.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4CPBG@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
MMS3_k127_3159424_11	469383.Cwoe_3307	2.105e-124	406.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMS3_k127_3159424_13	525904.Tter_2339	4.263e-114	382.0	COG1914@1|root,COG1914@2|Bacteria,2NNYP@2323|unclassified Bacteria	2|Bacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS07840	Nramp
MMS3_k127_3159424_19	487521.OCU_23230	3.35e-89	313.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,232UC@1762|Mycobacteriaceae	201174|Actinobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
MMS3_k127_3159424_29	929712.KI912613_gene4300	4.25e-39	157.0	2AUAR@1|root,31JYD@2|Bacteria,2HNZF@201174|Actinobacteria,4CQ8Y@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3159424_18	247490.KSU1_C0355	1.048e-89	309.0	COG1322@1|root,COG1322@2|Bacteria,2J2TY@203682|Planctomycetes	203682|Planctomycetes	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
MMS3_k127_3159424_14	1380390.JIAT01000001_gene5116	5.529e-108	357.0	COG2267@1|root,COG2267@2|Bacteria,2I2IM@201174|Actinobacteria,4CQH4@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_3159424_16	1128421.JAGA01000003_gene3260	2.938e-100	358.0	COG5001@1|root,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
MMS3_k127_3159424_20	1380390.JIAT01000015_gene5814	2.091e-83	287.0	COG0583@1|root,COG0583@2|Bacteria,2GKT0@201174|Actinobacteria,4CPXI@84995|Rubrobacteria	84995|Rubrobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_3159424_37	471852.Tcur_2015	4.044e-07	61.0	COG0589@1|root,COG0589@2|Bacteria,2GKQ1@201174|Actinobacteria,4EM9N@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_3159424_9	1380390.JIAT01000002_gene5976	2.628e-133	446.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CPX5@84995|Rubrobacteria	84995|Rubrobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
MMS3_k127_3159424_15	469383.Cwoe_2648	3.072e-107	352.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CPZA@84995|Rubrobacteria	84995|Rubrobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_3159424_2	1380390.JIAT01000002_gene5978	1.012e-241	750.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CPB5@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
MMS3_k127_3159424_34	479432.Sros_7916	3.069e-25	110.0	2E8UC@1|root,3334W@2|Bacteria,2GPHR@201174|Actinobacteria,4EK6N@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3159424_10	469383.Cwoe_2653	6.038e-126	418.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CQ90@84995|Rubrobacteria	84995|Rubrobacteria	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
MMS3_k127_3159424_21	1380390.JIAT01000002_gene5989	1.811e-65	233.0	COG1933@1|root,COG1933@2|Bacteria,2GU4W@201174|Actinobacteria,4CQ2Q@84995|Rubrobacteria	84995|Rubrobacteria	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
MMS3_k127_3159424_22	469383.Cwoe_2656	1.02e-62	218.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4CQFJ@84995|Rubrobacteria	84995|Rubrobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
MMS3_k127_3159424_24	469383.Cwoe_2657	1.265e-57	207.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,4CQME@84995|Rubrobacteria	84995|Rubrobacteria	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
MMS3_k127_3159424_4	1283299.AUKG01000005_gene64	1.358e-203	640.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CP7J@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS3_k127_3159424_23	1380390.JIAT01000002_gene5996	4.543e-62	225.0	COG1792@1|root,COG1792@2|Bacteria,2HP68@201174|Actinobacteria,4CQHY@84995|Rubrobacteria	84995|Rubrobacteria	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
MMS3_k127_3159424_7	469383.Cwoe_2661	1.437e-148	495.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CPBN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMS3_k127_3159424_12	469383.Cwoe_2662	9.967e-119	394.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4CPV0@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
MMS3_k127_3159424_0	469383.Cwoe_2663	2.289e-299	929.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CPSJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
MMS3_k127_3159424_32	469383.Cwoe_2664	2e-33	140.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4CQJ4@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
MMS3_k127_3159424_31	469383.Cwoe_2665	6.296e-34	138.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CQPP@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
MMS3_k127_3159424_6	469383.Cwoe_2668	5.522e-165	531.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CPMW@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
MMS3_k127_3159424_8	469383.Cwoe_2670	1.586e-141	463.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CR1D@84995|Rubrobacteria	84995|Rubrobacteria	E	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
MMS3_k127_3159424_5	469383.Cwoe_2672	5.439e-172	557.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CPDP@84995|Rubrobacteria	84995|Rubrobacteria	E	Aldehyde dehydrogenase family	-	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_3159424_25	469383.Cwoe_2673	1.432e-57	207.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CQ75@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS3_k127_3159424_28	469383.Cwoe_2674	4.313e-45	166.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CQDN@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
MMS3_k127_3183806_6	1120936.KB907215_gene3950	3.035e-09	63.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
MMS3_k127_3183806_1	1380390.JIAT01000010_gene3563	1.379e-185	586.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CPSD@84995|Rubrobacteria	84995|Rubrobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
MMS3_k127_3183806_3	1380390.JIAT01000010_gene3565	1.142e-94	314.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CQDJ@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMS3_k127_3183806_0	469383.Cwoe_4211	1.783e-310	962.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
MMS3_k127_3183806_4	1380390.JIAT01000010_gene4929	3.044e-45	169.0	COG3945@1|root,COG3945@2|Bacteria,2IA3E@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_3183806_2	469383.Cwoe_4205	1.969e-102	336.0	2AV8W@1|root,31KZS@2|Bacteria,2HPQ4@201174|Actinobacteria,4CR2W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3183806_5	479433.Caci_5578	6.072e-30	137.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K19720	ko04611,ko04926,ko04933,ko04974,ko05146,map04611,map04926,map04933,map04974,map05146	-	-	-	ko00000,ko00001,ko00536	-	-	-	BNR_2,Peptidase_M23,SLT_2,VCBS
MMS3_k127_3204478_47	570967.JMLV01000014_gene2010	6.107e-06	54.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,2JQ9B@204441|Rhodospirillales	204441|Rhodospirillales	L	Belongs to the 'phage' integrase family. XerC subfamily	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_3204478_21	469383.Cwoe_3668	9.978e-104	346.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4CTEF@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3204478_0	469383.Cwoe_3669	6.128e-273	848.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CPCE@84995|Rubrobacteria	84995|Rubrobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
MMS3_k127_3204478_32	1283299.AUKG01000002_gene4763	5.376e-64	225.0	2BR5U@1|root,32K3Y@2|Bacteria,2HP6A@201174|Actinobacteria,4CQI3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3204478_41	1283299.AUKG01000002_gene4762	5.261e-29	118.0	2A2N3@1|root,30R0G@2|Bacteria,2HRE5@201174|Actinobacteria,4CTC9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3204478_25	469383.Cwoe_3672	2.069e-86	302.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4CQ3U@84995|Rubrobacteria	84995|Rubrobacteria	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
MMS3_k127_3204478_48	1205680.CAKO01000014_gene106	0.0004289	50.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
MMS3_k127_3204478_42	469383.Cwoe_3675	2.026e-26	124.0	COG0792@1|root,COG0792@2|Bacteria,2HP2Y@201174|Actinobacteria,4CQE0@84995|Rubrobacteria	84995|Rubrobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
MMS3_k127_3204478_24	469383.Cwoe_3676	3.218e-89	301.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CQ01@84995|Rubrobacteria	84995|Rubrobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
MMS3_k127_3204478_27	1283299.AUKG01000002_gene4753	1.191e-79	274.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CQK4@84995|Rubrobacteria	84995|Rubrobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
MMS3_k127_3204478_31	1283299.AUKG01000002_gene4752	5.216e-65	231.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CQ3H@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
MMS3_k127_3204478_19	469383.Cwoe_3679	6.947e-108	357.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CPQ4@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
MMS3_k127_3204478_36	469383.Cwoe_3680	1.608e-40	157.0	COG0806@1|root,COG0806@2|Bacteria	2|Bacteria	J	ribosome binding	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
MMS3_k127_3204478_43	1283299.AUKG01000002_gene4749	2.977e-25	107.0	COG1837@1|root,COG1837@2|Bacteria,2HNEK@201174|Actinobacteria,4CQQV@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
MMS3_k127_3204478_39	469383.Cwoe_3682	5.809e-34	132.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CQNJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
MMS3_k127_3204478_4	1283299.AUKG01000002_gene4747	1.333e-213	675.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CP5Y@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
MMS3_k127_3204478_10	469383.Cwoe_3684	6.409e-133	432.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CPG3@84995|Rubrobacteria	84995|Rubrobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMS3_k127_3204478_35	1380390.JIAT01000010_gene4253	2.369e-41	156.0	COG1585@1|root,COG1585@2|Bacteria,2HPFR@201174|Actinobacteria,4CQU5@84995|Rubrobacteria	84995|Rubrobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
MMS3_k127_3204478_11	469383.Cwoe_3686	8.778e-133	431.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CPF9@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
MMS3_k127_3204478_2	1283299.AUKG01000002_gene4740	2.495e-222	722.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CPIP@84995|Rubrobacteria	84995|Rubrobacteria	D	RecF/RecN/SMC N terminal domain	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
MMS3_k127_3204478_23	1380390.JIAT01000010_gene4248	2.144e-94	314.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CPZ4@84995|Rubrobacteria	84995|Rubrobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
MMS3_k127_3204478_40	1283299.AUKG01000002_gene4738	1.082e-32	128.0	COG0236@1|root,COG0236@2|Bacteria,2HNF1@201174|Actinobacteria,4CQR2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
MMS3_k127_3204478_15	1283299.AUKG01000002_gene4737	3.854e-116	385.0	COG0416@1|root,COG0416@2|Bacteria,2I8WT@201174|Actinobacteria,4CQB5@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
MMS3_k127_3204478_33	1380390.JIAT01000010_gene4240	3.676e-54	202.0	COG1399@1|root,COG1399@2|Bacteria,2HQSM@201174|Actinobacteria,4CSGR@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
MMS3_k127_3204478_3	1380390.JIAT01000010_gene4238	1.251e-217	689.0	COG0318@1|root,COG0318@2|Bacteria,2GKDF@201174|Actinobacteria,4CPC4@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3204478_26	469383.Cwoe_3698	9.986e-81	270.0	COG0711@1|root,COG0711@2|Bacteria,2HNZ4@201174|Actinobacteria,4CQ8B@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3204478_29	1380390.JIAT01000010_gene4225	3.641e-70	241.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CQ3G@84995|Rubrobacteria	84995|Rubrobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS3_k127_3204478_34	469383.Cwoe_3700	1.092e-47	180.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4CQ9U@84995|Rubrobacteria	84995|Rubrobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
MMS3_k127_3204478_1	469383.Cwoe_3701	1.282e-232	743.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CPM1@84995|Rubrobacteria	84995|Rubrobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
MMS3_k127_3204478_14	1380390.JIAT01000011_gene2775	6.42e-117	399.0	COG1463@1|root,COG1463@2|Bacteria,2GMMT@201174|Actinobacteria,4CRZH@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
MMS3_k127_3204478_17	1380390.JIAT01000011_gene2774	9.666e-114	390.0	COG1463@1|root,COG1463@2|Bacteria,2ICM7@201174|Actinobacteria,4CR1J@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
MMS3_k127_3204478_16	1283299.AUKG01000001_gene2859	6.797e-115	395.0	COG1463@1|root,COG1463@2|Bacteria,2I8TQ@201174|Actinobacteria,4CRI0@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
MMS3_k127_3204478_13	1380390.JIAT01000011_gene2772	3.887e-117	397.0	COG1463@1|root,COG1463@2|Bacteria,2HNKW@201174|Actinobacteria,4CPPQ@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
MMS3_k127_3204478_20	469383.Cwoe_1622	1.492e-105	361.0	COG1463@1|root,COG1463@2|Bacteria,2IDGH@201174|Actinobacteria,4CREE@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
MMS3_k127_3204478_9	1283299.AUKG01000001_gene2914	1.354e-140	478.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4CPBG@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
MMS3_k127_3204478_18	1380390.JIAT01000011_gene2771	3.385e-109	373.0	COG1463@1|root,COG1463@2|Bacteria,2GMHC@201174|Actinobacteria,4CS82@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
MMS3_k127_3204478_12	469383.Cwoe_0406	7.791e-120	397.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4CP9S@84995|Rubrobacteria	84995|Rubrobacteria	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_3204478_5	469383.Cwoe_4008	2.753e-202	636.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4CPEP@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3204478_8	981369.JQMJ01000004_gene1085	1.388e-159	519.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
MMS3_k127_3204478_22	469383.Cwoe_1180	3.297e-98	325.0	COG0847@1|root,COG0847@2|Bacteria,2I2KI@201174|Actinobacteria,4CRDT@84995|Rubrobacteria	84995|Rubrobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
MMS3_k127_3204478_28	469383.Cwoe_4579	2.552e-72	260.0	COG1994@1|root,COG1994@2|Bacteria,2H6BD@201174|Actinobacteria,4CS7E@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3204478_30	1380390.JIAT01000001_gene5113	1.26e-66	230.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CQII@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
MMS3_k127_3204478_7	469383.Cwoe_4583	1.998e-179	597.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4CPE0@84995|Rubrobacteria	84995|Rubrobacteria	K	RNB	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
MMS3_k127_3204478_37	395961.Cyan7425_3650	1.972e-40	171.0	COG0793@1|root,COG0793@2|Bacteria,1G1YJ@1117|Cyanobacteria,3KGCB@43988|Cyanothece	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
MMS3_k127_3204478_6	469383.Cwoe_4588	3.872e-195	615.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CP8P@84995|Rubrobacteria	84995|Rubrobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_3204478_38	1048339.KB913029_gene4054	2.287e-38	154.0	2EE69@1|root,3380V@2|Bacteria,2GR09@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3204478_45	525909.Afer_0033	1.224e-07	58.0	COG1396@1|root,COG1669@1|root,COG1396@2|Bacteria,COG1669@2|Bacteria,2HGH2@201174|Actinobacteria,4CNEF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
MMS3_k127_3204478_44	1283299.AUKG01000002_gene3936	6.282e-14	71.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4CP6W@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
MMS3_k127_3225856_10	1463887.KL589973_gene1372	2.278e-61	221.0	COG4291@1|root,COG4291@2|Bacteria,2GIW8@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
MMS3_k127_3225856_20	929712.KI912613_gene385	7.683e-05	53.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0008150,GO:0040007	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_3225856_7	1380390.JIAT01000009_gene1294	5.152e-92	308.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4CPHV@84995|Rubrobacteria	84995|Rubrobacteria	L	Endonuclease NucS	-	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
MMS3_k127_3225856_16	1122939.ATUD01000004_gene3865	5.286e-26	123.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4CU6Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
MMS3_k127_3225856_17	981369.JQMJ01000004_gene4060	1.833e-21	108.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,2NFMM@228398|Streptacidiphilus	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
MMS3_k127_3225856_15	408672.NBCG_04983	1.136e-37	159.0	COG0501@1|root,COG0501@2|Bacteria,2GRBS@201174|Actinobacteria,4DPZ2@85009|Propionibacteriales	201174|Actinobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
MMS3_k127_3225856_6	1283299.AUKG01000001_gene1291	3.239e-120	391.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4CPB7@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_3225856_0	1283299.AUKG01000001_gene1281	0.0	1888.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CPG1@84995|Rubrobacteria	84995|Rubrobacteria	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,Biotin_lipoyl,E1_dh,E3_binding,OxoGdeHyase_C,Transket_pyr
MMS3_k127_3225856_19	469383.Cwoe_1043	7.649e-13	78.0	2AXGF@1|root,31PG3@2|Bacteria,2HRV7@201174|Actinobacteria,4CTYJ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3225856_8	1283299.AUKG01000001_gene1280	8.423e-85	289.0	COG1051@1|root,COG1051@2|Bacteria,2HNRC@201174|Actinobacteria,4CPYR@84995|Rubrobacteria	84995|Rubrobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_3225856_1	469383.Cwoe_1045	1.068e-212	678.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	agpS	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_3225856_11	996637.SGM_2030	3.16e-57	212.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_3225856_14	469383.Cwoe_1048	1.69e-39	149.0	2AU96@1|root,31JWJ@2|Bacteria,2HNY7@201174|Actinobacteria,4CQ7D@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3225856_3	58344.JOEL01000015_gene6440	1.776e-139	451.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3225856_4	235985.BBPN01000009_gene3713	1.606e-131	435.0	COG0842@1|root,COG0842@2|Bacteria,2GP9E@201174|Actinobacteria,2NHGS@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_3225856_2	359.CN09_03790	2.839e-145	467.0	COG2141@1|root,COG2141@2|Bacteria,1MUTJ@1224|Proteobacteria,2TTZI@28211|Alphaproteobacteria,4B7EI@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3225856_12	469383.Cwoe_1049	1.659e-56	201.0	COG0346@1|root,COG0346@2|Bacteria,2IIM8@201174|Actinobacteria,4CQQJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
MMS3_k127_3225856_5	298653.Franean1_6210	7.224e-131	443.0	COG0477@1|root,COG0477@2|Bacteria,2HEW6@201174|Actinobacteria,4EU3U@85013|Frankiales	201174|Actinobacteria	U	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3225856_13	1120934.KB894403_gene371	5.427e-51	192.0	COG1216@1|root,COG1216@2|Bacteria,2IIII@201174|Actinobacteria,4EEA1@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3225856_9	1380390.JIAT01000009_gene1257	3.367e-83	284.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,4CQ3N@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_3269763_5	469383.Cwoe_5793	2.13e-51	185.0	COG0662@1|root,COG0662@2|Bacteria,2HRG6@201174|Actinobacteria,4CTF8@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_3269763_1	710686.Mycsm_06153	1.69e-143	469.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,23D0V@1762|Mycobacteriaceae	201174|Actinobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
MMS3_k127_3269763_2	882082.SaccyDRAFT_0979	8.146e-110	370.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4EA5T@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH dehydrogenase, FAD-containing subunit	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_3269763_3	309801.trd_A0395	3.237e-77	271.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
MMS3_k127_3269763_6	682795.AciX8_2893	8.468e-29	129.0	COG3336@1|root,COG3336@2|Bacteria,3Y3CM@57723|Acidobacteria,2JKAF@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Cytochrome c oxidase caa3-type, assembly factor CtaG-related	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
MMS3_k127_3269763_7	269482.Bcep1808_5832	0.0006346	50.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VM0G@28216|Betaproteobacteria,1K22G@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298,ko:K15408	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1,COX3
MMS3_k127_3269763_0	1121877.JQKF01000024_gene2410	9.633e-210	672.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CNMG@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
MMS3_k127_3269763_4	1121877.JQKF01000024_gene2409	2.224e-60	218.0	COG1622@1|root,COG1622@2|Bacteria,2HGN7@201174|Actinobacteria,4CNP4@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
MMS3_k127_3289696_23	469383.Cwoe_2478	1.434e-35	139.0	COG0346@1|root,COG0346@2|Bacteria,2HR81@201174|Actinobacteria,4CT42@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_3289696_15	1380390.JIAT01000011_gene2722	8.097e-64	233.0	COG2199@1|root,COG2199@2|Bacteria,2IR83@201174|Actinobacteria,4CRH1@84995|Rubrobacteria	84995|Rubrobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMS3_k127_3289696_10	469383.Cwoe_4738	7.76e-96	330.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4CQJ5@84995|Rubrobacteria	84995|Rubrobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
MMS3_k127_3289696_19	1173028.ANKO01000194_gene6031	7.161e-49	197.0	COG0625@1|root,COG0625@2|Bacteria,1G5EX@1117|Cyanobacteria	1117|Cyanobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
MMS3_k127_3289696_6	525909.Afer_1995	6.226e-157	509.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CNTR@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMS3_k127_3289696_18	269797.Mbar_A0743	1.641e-53	192.0	COG0229@1|root,arCOG02815@2157|Archaea,2XXVK@28890|Euryarchaeota,2N9RZ@224756|Methanomicrobia	224756|Methanomicrobia	C	TIGRFAM methionine-R-sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
MMS3_k127_3289696_4	1123258.AQXZ01000011_gene1526	8.494e-207	655.0	COG0477@1|root,COG0477@2|Bacteria,2GJSC@201174|Actinobacteria,4FY0W@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
MMS3_k127_3289696_24	1380390.JIAT01000016_gene5483	2.668e-35	142.0	COG0789@1|root,COG0789@2|Bacteria,2HR8S@201174|Actinobacteria,4CT53@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMS3_k127_3289696_13	1120948.KB903243_gene2611	1.91e-72	259.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DYUU@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3289696_14	644966.Tmar_1679	1.966e-68	243.0	COG0842@1|root,COG0842@2|Bacteria,1UYEB@1239|Firmicutes,24BUQ@186801|Clostridia,3WDNI@538999|Clostridiales incertae sedis	186801|Clostridia	V	daunorubicin resistance ABC transporter membrane protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_3289696_12	471852.Tcur_0949	7.351e-74	258.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4EPQU@85012|Streptosporangiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS3_k127_3289696_27	469383.Cwoe_2923	4.003e-16	79.0	2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3289696_3	1380390.JIAT01000016_gene5495	5.002e-226	719.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPH0@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_3289696_2	469383.Cwoe_2921	1.167e-227	725.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPT4@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_3289696_9	1380390.JIAT01000016_gene5498	5.435e-101	335.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CPKV@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
MMS3_k127_3289696_16	1380390.JIAT01000016_gene5499	1.236e-61	216.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,4CQ18@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
MMS3_k127_3289696_1	1283299.AUKG01000004_gene1080	8.463e-235	749.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2HF4S@201174|Actinobacteria,4CPSY@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
MMS3_k127_3289696_28	1122939.ATUD01000004_gene3711	6.825e-07	53.0	2AVK1@1|root,31MCR@2|Bacteria,2HPG1@201174|Actinobacteria,4CQUK@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3289696_0	1283299.AUKG01000004_gene1089	0.0	1032.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4CRVW@84995|Rubrobacteria	84995|Rubrobacteria	C	Inorganic H+ pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	H_PPase
MMS3_k127_3289696_5	469383.Cwoe_2903	3.654e-173	552.0	COG2170@1|root,COG2170@2|Bacteria,2H5B4@201174|Actinobacteria,4CQ42@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
MMS3_k127_3289696_8	469383.Cwoe_2902	2.181e-103	340.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4CPVR@84995|Rubrobacteria	84995|Rubrobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,DUF836,Put_DNA-bind_N
MMS3_k127_3289696_26	469383.Cwoe_2901	2.254e-19	98.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
MMS3_k127_3289696_7	1283299.AUKG01000004_gene1094	4.609e-127	419.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CPNE@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
MMS3_k127_3289696_17	1283299.AUKG01000004_gene1095	9.599e-57	209.0	COG0454@1|root,COG0456@2|Bacteria,2HPAC@201174|Actinobacteria,4CQNP@84995|Rubrobacteria	84995|Rubrobacteria	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
MMS3_k127_3289696_20	469383.Cwoe_2898	2.673e-47	186.0	COG1214@1|root,COG1214@2|Bacteria,2HP59@201174|Actinobacteria,4CQH7@84995|Rubrobacteria	84995|Rubrobacteria	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
MMS3_k127_3289696_21	469383.Cwoe_2896	1.675e-39	156.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4CQQP@84995|Rubrobacteria	84995|Rubrobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
MMS3_k127_3289696_11	1380390.JIAT01000016_gene5539	3.877e-90	304.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria	84995|Rubrobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_3289696_22	1380390.JIAT01000010_gene4173	1.35e-37	143.0	COG3677@1|root,COG3677@2|Bacteria,2HGBB@201174|Actinobacteria,4CTUD@84995|Rubrobacteria	84995|Rubrobacteria	K	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3289696_29	685778.AORL01000009_gene3195	9.728e-05	45.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,2K3A6@204457|Sphingomonadales	204457|Sphingomonadales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
MMS3_k127_338728_4	1283299.AUKG01000004_gene946	0.0003462	48.0	COG3166@1|root,COG3166@2|Bacteria,2HPHC@201174|Actinobacteria,4CQVM@84995|Rubrobacteria	84995|Rubrobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_338728_2	1380390.JIAT01000017_gene5278	1.301e-23	111.0	2AVF2@1|root,31M71@2|Bacteria,2HPWF@201174|Actinobacteria,4CRB2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM
MMS3_k127_338728_3	1283299.AUKG01000004_gene944	1.076e-10	73.0	2B0FJ@1|root,31ST2@2|Bacteria,2HQ6F@201174|Actinobacteria,4CRPF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_338728_0	469383.Cwoe_3057	1.652e-190	601.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CPJG@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
MMS3_k127_338728_1	1380390.JIAT01000017_gene5275	1.031e-108	369.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4CPMA@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
MMS3_k127_3447617_3	903818.KI912268_gene1318	3.957e-71	261.0	COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
MMS3_k127_3447617_1	1283299.AUKG01000004_gene1116	2.826e-155	501.0	COG2230@1|root,COG2230@2|Bacteria,2GM5H@201174|Actinobacteria,4CSA0@84995|Rubrobacteria	84995|Rubrobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
MMS3_k127_3447617_4	887062.HGR_05454	1.036e-64	237.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,4AARP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
MMS3_k127_3447617_0	469383.Cwoe_4724	4.932e-172	549.0	COG2907@1|root,COG2907@2|Bacteria,2GJMW@201174|Actinobacteria,4CRSU@84995|Rubrobacteria	84995|Rubrobacteria	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMS3_k127_3447617_2	909613.UO65_2927	1.248e-84	289.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4E0AR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3460563_12	469383.Cwoe_1642	1.319e-62	222.0	COG0715@1|root,COG0715@2|Bacteria,2HFU1@201174|Actinobacteria,4CQ47@84995|Rubrobacteria	84995|Rubrobacteria	P	NMT1/THI5 like	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
MMS3_k127_3460563_16	1122939.ATUD01000003_gene3519	1.083e-33	142.0	COG0589@1|root,COG0589@2|Bacteria,2HR8H@201174|Actinobacteria,4CT4U@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_3460563_11	469383.Cwoe_1298	4.376e-87	293.0	COG2197@1|root,COG2197@2|Bacteria,2IIZS@201174|Actinobacteria,4CRXE@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_3460563_5	1380390.JIAT01000009_gene1461	6.991e-151	484.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4CPGX@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
MMS3_k127_3460563_6	309801.trd_0582	1.986e-149	478.0	COG1064@1|root,COG1064@2|Bacteria,2G829@200795|Chloroflexi,27YST@189775|Thermomicrobia	189775|Thermomicrobia	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
MMS3_k127_3460563_10	1380390.JIAT01000011_gene2787	1.484e-94	320.0	COG0122@1|root,COG0122@2|Bacteria,2HPWW@201174|Actinobacteria,4CRBJ@84995|Rubrobacteria	84995|Rubrobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
MMS3_k127_3460563_4	469383.Cwoe_1636	1.016e-171	545.0	COG0454@1|root,COG0456@2|Bacteria,2GNAV@201174|Actinobacteria,4CQ54@84995|Rubrobacteria	84995|Rubrobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3460563_2	1122939.ATUD01000002_gene1143	8.192e-209	661.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4CP6E@84995|Rubrobacteria	84995|Rubrobacteria	H	Aminotransferase class I and II	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_3460563_18	1283299.AUKG01000001_gene2868	3.404e-31	130.0	2AU98@1|root,30HFP@2|Bacteria,2HYG7@201174|Actinobacteria,4CQNQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3460563_14	1380390.JIAT01000011_gene2779	1.454e-41	159.0	2FIW0@1|root,34AM7@2|Bacteria,2HPD8@201174|Actinobacteria,4CQR1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3460563_13	469383.Cwoe_1630	3.745e-44	178.0	COG3382@1|root,COG3382@2|Bacteria,2HAYZ@201174|Actinobacteria,4CT9S@84995|Rubrobacteria	84995|Rubrobacteria	S	B3 4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3460563_17	469383.Cwoe_1629	2.548e-31	137.0	COG1225@1|root,COG1225@2|Bacteria,2HT4T@201174|Actinobacteria,4CSH8@84995|Rubrobacteria	84995|Rubrobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMS3_k127_3460563_1	1380390.JIAT01000011_gene2776	2.23e-235	761.0	COG1033@1|root,COG1033@2|Bacteria,2I731@201174|Actinobacteria,4CR6J@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
MMS3_k127_3460563_7	469383.Cwoe_1621	4.613e-132	427.0	COG1127@1|root,COG1127@2|Bacteria,2GJ1T@201174|Actinobacteria,4CPHI@84995|Rubrobacteria	84995|Rubrobacteria	Q	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
MMS3_k127_3460563_8	1380390.JIAT01000011_gene2768	2.453e-131	424.0	COG0767@1|root,COG0767@2|Bacteria,2GJ27@201174|Actinobacteria,4CPTC@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
MMS3_k127_3460563_9	1122939.ATUD01000002_gene1136	5.377e-130	422.0	COG0767@1|root,COG0767@2|Bacteria,2IAUN@201174|Actinobacteria,4CR2S@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
MMS3_k127_3460563_15	1283299.AUKG01000001_gene2852	1.126e-37	153.0	2AUSI@1|root,31KFK@2|Bacteria,2HPAD@201174|Actinobacteria,4CQNT@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3460563_3	1038869.AXAN01000048_gene4514	3.339e-178	571.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VZW7@28216|Betaproteobacteria,1K2N1@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
MMS3_k127_3460563_0	1380390.JIAT01000011_gene2759	0.0	1810.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CPS6@84995|Rubrobacteria	84995|Rubrobacteria	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
MMS3_k127_3476610_19	1120948.KB903229_gene5320	3.21e-33	141.0	29BBV@1|root,2ZYA6@2|Bacteria,2ICWN@201174|Actinobacteria	201174|Actinobacteria	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
MMS3_k127_3476610_12	105422.BBPM01000094_gene5275	1.037e-54	206.0	COG4097@1|root,COG4097@2|Bacteria,2GQH2@201174|Actinobacteria,2NG1I@228398|Streptacidiphilus	201174|Actinobacteria	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
MMS3_k127_3476610_13	525909.Afer_1195	4.45e-50	192.0	COG4188@1|root,COG4188@2|Bacteria,2HGN0@201174|Actinobacteria,4CNNA@84992|Acidimicrobiia	84992|Acidimicrobiia	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3476610_20	1121877.JQKF01000013_gene272	4.96e-24	112.0	COG0500@1|root,COG2226@2|Bacteria,2HGMM@201174|Actinobacteria,4CNKY@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_3476610_22	33876.JNXY01000039_gene6645	1.137e-14	87.0	COG1141@1|root,COG1141@2|Bacteria,2GSJ7@201174|Actinobacteria,4DGIB@85008|Micromonosporales	201174|Actinobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_15
MMS3_k127_3476610_4	1089544.KB912942_gene1565	2.51e-102	349.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,4E6BU@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMS3_k127_3476610_5	1172181.KB911708_gene8108	4.284e-87	300.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMS3_k127_3476610_6	469383.Cwoe_4710	2.145e-74	259.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CQ94@84995|Rubrobacteria	84995|Rubrobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_3476610_3	469383.Cwoe_4709	1.166e-109	383.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	cpxA	-	2.7.13.3	ko:K02484,ko:K07640,ko:K07643,ko:K07645,ko:K07649,ko:K19609	ko01503,ko02020,ko02024,map01503,map02020,map02024	M00447,M00451,M00453,M00457,M00721,M00722,M00727,M00728,M00770	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,CpxA_peri,HAMP,HATPase_c,HK_sensor,HisKA
MMS3_k127_3476610_9	1120949.KB903324_gene3292	5.523e-63	232.0	29BBV@1|root,2ZYA6@2|Bacteria,2ICWN@201174|Actinobacteria	201174|Actinobacteria	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
MMS3_k127_3476610_7	929712.KI912613_gene1805	4.283e-65	234.0	COG0382@1|root,COG0382@2|Bacteria,2GJ6P@201174|Actinobacteria,4CTED@84995|Rubrobacteria	84995|Rubrobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
MMS3_k127_3476610_2	1463856.JOHY01000011_gene6988	5.766e-127	421.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.98.3	ko:K16653	-	-	-	-	ko00000,ko01000	-	-	-	ALO,FAD_binding_4
MMS3_k127_3476610_10	1463854.JOHT01000008_gene5622	6.014e-60	220.0	COG0300@1|root,COG0300@2|Bacteria,2GNPI@201174|Actinobacteria	201174|Actinobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	phbB	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
MMS3_k127_3476610_11	1380390.JIAT01000013_gene150	1.042e-55	197.0	COG0394@1|root,COG0394@2|Bacteria,2HFR2@201174|Actinobacteria,4CT4Z@84995|Rubrobacteria	84995|Rubrobacteria	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
MMS3_k127_3476610_0	1907.SGLAU_28865	1.273e-186	597.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
MMS3_k127_3476610_14	1380390.JIAT01000009_gene1922	2.392e-47	184.0	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria,4CQI6@84995|Rubrobacteria	84995|Rubrobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
MMS3_k127_3476610_18	318424.EU78_20405	2.329e-35	142.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,232P5@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
MMS3_k127_3476610_23	749927.AMED_6025	1.175e-14	81.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4E4U9@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMS3_k127_3476610_1	67257.JODR01000005_gene2115	1.617e-162	526.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3476610_17	1157637.KB892097_gene1197	2.141e-35	149.0	2CXR2@1|root,32T2F@2|Bacteria,2I2M0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3476610_21	1157637.KB892097_gene1199	9.46e-15	84.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
MMS3_k127_3476610_8	469383.Cwoe_1039	9.045e-65	226.0	COG0432@1|root,COG0432@2|Bacteria,2HNZT@201174|Actinobacteria,4CQ99@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
MMS3_k127_3476610_16	469383.Cwoe_4936	1.321e-44	171.0	2EE69@1|root,3380V@2|Bacteria,2GR09@201174|Actinobacteria,4CTGN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3476610_15	164757.Mjls_3969	4.966e-47	172.0	COG0748@1|root,COG0748@2|Bacteria,2IP0W@201174|Actinobacteria,239MR@1762|Mycobacteriaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_3488940_7	469383.Cwoe_1764	2.891e-49	184.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CQ6Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
MMS3_k127_3488940_8	1283299.AUKG01000001_gene3042	2.716e-26	110.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
MMS3_k127_3488940_1	1283299.AUKG01000001_gene3043	2.666e-170	549.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
MMS3_k127_3488940_5	1380390.JIAT01000014_gene6246	1.356e-96	324.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4CPNR@84995|Rubrobacteria	84995|Rubrobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
MMS3_k127_3488940_0	1380390.JIAT01000012_gene2949	2.487e-180	573.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CQYR@84995|Rubrobacteria	84995|Rubrobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_3488940_4	1380390.JIAT01000017_gene5245	3.327e-114	387.0	COG3409@1|root,COG3409@2|Bacteria,2HQQI@201174|Actinobacteria,4CSDC@84995|Rubrobacteria	84995|Rubrobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
MMS3_k127_3488940_3	1283299.AUKG01000001_gene3048	4.324e-127	415.0	COG4948@1|root,COG4948@2|Bacteria,2I7AE@201174|Actinobacteria,4CPIJ@84995|Rubrobacteria	84995|Rubrobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3488940_10	469383.Cwoe_1773	9.644e-18	94.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
MMS3_k127_3488940_2	469383.Cwoe_1774	4.884e-162	524.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
MMS3_k127_3488940_11	1122939.ATUD01000002_gene1141	8.091e-11	70.0	2BH9C@1|root,32BAU@2|Bacteria,2HP96@201174|Actinobacteria,4CQMF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3488940_9	1283299.AUKG01000001_gene3052	7.819e-23	102.0	2AUTJ@1|root,31KGM@2|Bacteria,2HPBH@201174|Actinobacteria,4CQPY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3488940_6	469383.Cwoe_1779	2.297e-76	271.0	COG2247@1|root,COG2247@2|Bacteria,2I6I4@201174|Actinobacteria,4CU6H@84995|Rubrobacteria	84995|Rubrobacteria	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
MMS3_k127_3508764_4	469383.Cwoe_5859	1.656e-58	211.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4CQ1C@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
MMS3_k127_3508764_2	469383.Cwoe_5862	2.589e-165	526.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CP8W@84995|Rubrobacteria	84995|Rubrobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
MMS3_k127_3508764_5	1380390.JIAT01000009_gene1949	2.23e-42	163.0	COG0671@1|root,COG0671@2|Bacteria,2IIA1@201174|Actinobacteria,4CQUT@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
MMS3_k127_3508764_7	1380390.JIAT01000009_gene1926	1.174e-12	75.0	2AVH0@1|root,31M9B@2|Bacteria,2HPFP@201174|Actinobacteria,4CQTY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3508764_3	1380390.JIAT01000009_gene1925	1.98e-60	215.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
MMS3_k127_3508764_0	1380390.JIAT01000009_gene1924	7.636e-187	602.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CRWP@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
MMS3_k127_3508764_1	469383.Cwoe_5867	3.119e-171	544.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4CRVV@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3530427_2	743718.Isova_1371	3.38e-87	299.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4F410@85017|Promicromonosporaceae	201174|Actinobacteria	O	ATPases associated with a variety of cellular activities	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMS3_k127_3530427_3	867903.ThesuDRAFT_00394	1.285e-63	235.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia	186801|Clostridia	O	feS assembly protein SufB	-	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
MMS3_k127_3530427_1	479434.Sthe_1525	9.218e-143	466.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi,27Y1Z@189775|Thermomicrobia	189775|Thermomicrobia	E	Beta-eliminating lyase	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
MMS3_k127_3530427_4	1380390.JIAT01000009_gene525	1.745e-39	153.0	COG0822@1|root,COG0822@2|Bacteria,2HNZE@201174|Actinobacteria,4CQ8X@84995|Rubrobacteria	84995|Rubrobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMS3_k127_3530427_0	697303.Thewi_2632	3.533e-175	561.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,42FZU@68295|Thermoanaerobacterales	186801|Clostridia	O	TIGRFAM SUF system FeS cluster assembly, SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
MMS3_k127_3575492_28	469383.Cwoe_2913	5.72e-52	186.0	COG0446@1|root,COG0446@2|Bacteria,2H2SC@201174|Actinobacteria,4CRSC@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
MMS3_k127_3575492_34	1380390.JIAT01000010_gene4103	6.889e-18	97.0	2AVX1@1|root,31X3Y@2|Bacteria,2HYM4@201174|Actinobacteria,4CQWW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3575492_22	1380390.JIAT01000010_gene4104	6.807e-83	286.0	28RTZ@1|root,2ZE6B@2|Bacteria,2HQNJ@201174|Actinobacteria,4CS8Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
MMS3_k127_3575492_25	1380390.JIAT01000010_gene4105	2.903e-58	215.0	COG0619@1|root,COG0619@2|Bacteria,2IIUE@201174|Actinobacteria,4CRAP@84995|Rubrobacteria	84995|Rubrobacteria	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
MMS3_k127_3575492_4	469383.Cwoe_3799	8.296e-202	658.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CPZK@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
MMS3_k127_3575492_18	469383.Cwoe_3798	1.192e-120	413.0	COG1657@1|root,COG4720@1|root,COG1657@2|Bacteria,COG4720@2|Bacteria,2HPSE@201174|Actinobacteria,4CR5W@84995|Rubrobacteria	84995|Rubrobacteria	I	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	-
MMS3_k127_3575492_23	469383.Cwoe_3804	3.738e-75	263.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,4CQR4@84995|Rubrobacteria	84995|Rubrobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
MMS3_k127_3575492_9	1122939.ATUD01000008_gene2523	4.835e-164	525.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4CPAE@84995|Rubrobacteria	84995|Rubrobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
MMS3_k127_3575492_31	882083.SacmaDRAFT_1410	3.711e-37	143.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4E5KZ@85010|Pseudonocardiales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
MMS3_k127_3575492_8	1206733.BAGC01000012_gene5253	4.317e-165	541.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4FWKS@85025|Nocardiaceae	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
MMS3_k127_3575492_29	1122939.ATUD01000006_gene1767	2.942e-43	173.0	COG5640@1|root,COG5640@2|Bacteria,2GN18@201174|Actinobacteria,4CQDZ@84995|Rubrobacteria	84995|Rubrobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
MMS3_k127_3575492_1	1283299.AUKG01000002_gene4594	5.479e-223	706.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4CPYZ@84995|Rubrobacteria	84995|Rubrobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DAO_C
MMS3_k127_3575492_20	469383.Cwoe_3796	2.835e-105	359.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4CT4V@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
MMS3_k127_3575492_17	1283299.AUKG01000002_gene4598	9.747e-122	407.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4CQBF@84995|Rubrobacteria	84995|Rubrobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
MMS3_k127_3575492_24	1283299.AUKG01000002_gene4600	3.203e-74	255.0	2AW02@1|root,31MUH@2|Bacteria,2HQH7@201174|Actinobacteria,4CS2A@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3575492_2	1380390.JIAT01000016_gene5502	1.473e-214	683.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2GJ75@201174|Actinobacteria,4CPFI@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,Usp
MMS3_k127_3575492_32	1283299.AUKG01000002_gene4610	6.462e-33	147.0	2ETCF@1|root,33KWB@2|Bacteria,2HQ8W@201174|Actinobacteria,4CRSS@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
MMS3_k127_3575492_30	469383.Cwoe_3778	3.318e-42	160.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4CQT3@84995|Rubrobacteria	84995|Rubrobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
MMS3_k127_3575492_14	469383.Cwoe_3777	3.112e-134	438.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CPWG@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
MMS3_k127_3575492_35	1380390.JIAT01000010_gene4139	9.259e-12	78.0	COG2919@1|root,COG2919@2|Bacteria,2HQXX@201174|Actinobacteria,4CSQC@84995|Rubrobacteria	84995|Rubrobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3575492_5	1283299.AUKG01000002_gene4614	2.319e-183	588.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CPGN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
MMS3_k127_3575492_7	469383.Cwoe_3774	2.637e-166	539.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CP75@84995|Rubrobacteria	84995|Rubrobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_3575492_16	1380390.JIAT01000010_gene4142	1.552e-122	421.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CPND@84995|Rubrobacteria	84995|Rubrobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_3575492_10	469383.Cwoe_3773	1.704e-152	486.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CPF5@84995|Rubrobacteria	84995|Rubrobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
MMS3_k127_3575492_13	469383.Cwoe_3772	1.372e-143	471.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CQ2K@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
MMS3_k127_3575492_15	1380390.JIAT01000010_gene4146	5.923e-123	409.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CPQK@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
MMS3_k127_3575492_19	469383.Cwoe_3770	1.011e-112	378.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CPNI@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
MMS3_k127_3575492_11	469383.Cwoe_3759	4.388e-150	488.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CPYN@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_3575492_26	1408419.JHYG01000004_gene1326	1.078e-55	207.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,2JPRS@204441|Rhodospirillales	204441|Rhodospirillales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
MMS3_k127_3575492_33	469383.Cwoe_3758	3.043e-30	133.0	COG1589@1|root,COG1589@2|Bacteria,2HPRM@201174|Actinobacteria,4CR4Y@84995|Rubrobacteria	84995|Rubrobacteria	M	POTRA domain, FtsQ-type	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
MMS3_k127_3575492_6	1380390.JIAT01000010_gene4151	2.505e-176	558.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CP7W@84995|Rubrobacteria	84995|Rubrobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMS3_k127_3575492_12	1283299.AUKG01000002_gene4628	3.564e-145	472.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CP79@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
MMS3_k127_3575492_27	469383.Cwoe_3755	7.825e-54	191.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CQGM@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
MMS3_k127_3575492_3	1283299.AUKG01000002_gene4630	4.339e-204	645.0	COG0403@1|root,COG0403@2|Bacteria,2IBH2@201174|Actinobacteria,4CP8Z@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
MMS3_k127_3575492_0	1283299.AUKG01000002_gene4631	2.773e-250	782.0	COG1003@1|root,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4CPH8@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
MMS3_k127_3575492_21	469383.Cwoe_3749	4.736e-85	285.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CPN5@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
MMS3_k127_3580654_9	765911.Thivi_0886	1.56e-90	308.0	COG0451@1|root,COG0451@2|Bacteria,1MV73@1224|Proteobacteria,1RMKK@1236|Gammaproteobacteria,1WWDU@135613|Chromatiales	135613|Chromatiales	M	CDP-glucose 4,6-dehydratase	-	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_3580654_10	469383.Cwoe_5504	2.38e-89	304.0	COG1922@1|root,COG1922@2|Bacteria,2ICDG@201174|Actinobacteria,4CPUX@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
MMS3_k127_3580654_0	469383.Cwoe_5497	1.702e-174	580.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4CP6B@84995|Rubrobacteria	84995|Rubrobacteria	M	RmlD substrate binding domain	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_3580654_4	469383.Cwoe_5493	2.338e-156	503.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4CPAJ@84995|Rubrobacteria	84995|Rubrobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_3580654_12	1283299.AUKG01000001_gene3004	7.425e-85	289.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4CU6K@84995|Rubrobacteria	84995|Rubrobacteria	E	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
MMS3_k127_3580654_2	1380390.JIAT01000011_gene2876	8.566e-172	548.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4CSMA@84995|Rubrobacteria	84995|Rubrobacteria	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_3580654_8	1380390.JIAT01000009_gene2196	2.292e-107	357.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4CRDU@84995|Rubrobacteria	84995|Rubrobacteria	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
MMS3_k127_3580654_7	1380390.JIAT01000009_gene2188	2.945e-115	384.0	COG0438@1|root,COG0438@2|Bacteria,2GM53@201174|Actinobacteria,4CPAX@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
MMS3_k127_3580654_5	1380390.JIAT01000009_gene2187	1.043e-152	504.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,2H63M@201174|Actinobacteria,4CSKT@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3580654_6	469383.Cwoe_5510	1.825e-123	411.0	COG0438@1|root,COG0438@2|Bacteria,2HENX@201174|Actinobacteria,4CRKC@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_3580654_11	1380390.JIAT01000009_gene2185	8.284e-87	306.0	COG0438@1|root,COG0438@2|Bacteria,2HNR4@201174|Actinobacteria,4CPY6@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
MMS3_k127_3580654_15	1283299.AUKG01000001_gene2242	1.913e-08	63.0	2AWB0@1|root,31N6P@2|Bacteria,2HQUN@201174|Actinobacteria,4CSMC@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3580654_3	1380390.JIAT01000009_gene2183	1.222e-156	527.0	2AX0P@1|root,31NYQ@2|Bacteria,2HPNT@201174|Actinobacteria,4CR19@84995|Rubrobacteria	84995|Rubrobacteria	S	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_3580654_13	235985.BBPN01000021_gene6251	4.352e-20	98.0	COG0500@1|root,COG2835@1|root,COG2226@2|Bacteria,COG2835@2|Bacteria,2I34F@201174|Actinobacteria,2NNFP@228398|Streptacidiphilus	201174|Actinobacteria	Q	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
MMS3_k127_3580654_14	929712.KI912613_gene482	4.447e-19	97.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_3580654_1	469383.Cwoe_5516	5.781e-172	548.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CP93@84995|Rubrobacteria	84995|Rubrobacteria	GM	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
MMS3_k127_3582694_0	1380390.JIAT01000007_gene5188	7.112e-154	497.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CPNK@84995|Rubrobacteria	84995|Rubrobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
MMS3_k127_3582694_1	469383.Cwoe_3105	3.312e-145	475.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CPM8@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
MMS3_k127_3582694_2	1380390.JIAT01000003_gene5463	1.381e-87	295.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CQNS@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
MMS3_k127_3582694_4	1283299.AUKG01000002_gene5295	1.897e-26	111.0	COG0695@1|root,COG0695@2|Bacteria,2HPAH@201174|Actinobacteria,4CQNW@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutaredoxin	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
MMS3_k127_3582694_3	469383.Cwoe_3094	2.142e-54	195.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4CPMX@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
MMS3_k127_3590962_2	1283299.AUKG01000001_gene1319	1.488e-121	398.0	COG1363@1|root,COG1363@2|Bacteria,2ID5X@201174|Actinobacteria,4CP5U@84995|Rubrobacteria	84995|Rubrobacteria	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
MMS3_k127_3590962_5	797302.Halru_2542	1.072e-10	67.0	arCOG03006@1|root,arCOG03006@2157|Archaea,2XYR1@28890|Euryarchaeota,23WX6@183963|Halobacteria	183963|Halobacteria	S	COG0662 Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_3590962_3	1283299.AUKG01000001_gene2931	9.553e-56	214.0	COG2050@1|root,COG2050@2|Bacteria,2HPRC@201174|Actinobacteria,4CR4I@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
MMS3_k127_3590962_0	469383.Cwoe_1002	6.348e-282	886.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4CRAM@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
MMS3_k127_3590962_1	1380390.JIAT01000009_gene1319	3.402e-146	470.0	COG2214@1|root,COG2214@2|Bacteria,2HPSB@201174|Actinobacteria,4CR5P@84995|Rubrobacteria	84995|Rubrobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3590962_4	1380386.JIAW01000011_gene3280	2.109e-20	91.0	COG4291@1|root,COG4291@2|Bacteria,2GIW8@201174|Actinobacteria,237XC@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
MMS3_k127_3663181_6	469383.Cwoe_3722	3.546e-56	202.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4CPIX@84995|Rubrobacteria	84995|Rubrobacteria	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
MMS3_k127_3663181_7	469383.Cwoe_3721	1.035e-32	129.0	COG1198@1|root,COG1198@2|Bacteria	2|Bacteria	L	DNA replication, synthesis of RNA primer	-	-	-	-	-	-	-	-	-	-	-	-	zinc-ribbons_6
MMS3_k127_3663181_5	469383.Cwoe_3720	3.202e-83	282.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CQD2@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribulose-phosphate 3-epimerase	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
MMS3_k127_3663181_2	469383.Cwoe_3712	4.794e-135	450.0	COG2244@1|root,COG2244@2|Bacteria,2HRC7@201174|Actinobacteria,4CT9N@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
MMS3_k127_3663181_4	929712.KI912613_gene4228	7.031e-89	308.0	COG0500@1|root,COG2226@2|Bacteria,2HNEB@201174|Actinobacteria,4CP8F@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_3663181_1	469383.Cwoe_3710	1.109e-162	521.0	COG1215@1|root,COG1215@2|Bacteria,2I2PK@201174|Actinobacteria,4CPE1@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3663181_3	1380390.JIAT01000010_gene4207	8.06e-106	362.0	2AXGW@1|root,329SJ@2|Bacteria,2HNI6@201174|Actinobacteria,4CPHF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3663181_0	1380390.JIAT01000010_gene4208	8.71e-176	573.0	COG1807@1|root,COG1807@2|Bacteria,2HNIC@201174|Actinobacteria,4CPHR@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_3670929_0	395494.Galf_0059	3.936e-269	837.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,44V9S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_21,Pyr_redox_2,Pyr_redox_3
MMS3_k127_3670929_2	1380390.JIAT01000009_gene798	1.398e-64	237.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4CPHM@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
MMS3_k127_3670929_1	179408.Osc7112_5083	2.378e-138	445.0	COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria,1H7CT@1150|Oscillatoriales	1117|Cyanobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
MMS3_k127_3671763_6	1120944.JONS01000084_gene2533	2.832e-06	49.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4D3EM@85005|Actinomycetales	201174|Actinobacteria	L	Uracil-DNA glycosylase	udgB	GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_3671763_5	1237500.ANBA01000011_gene3294	3.562e-16	80.0	COG2608@1|root,COG2608@2|Bacteria,2GQK5@201174|Actinobacteria,4EKNK@85012|Streptosporangiales	201174|Actinobacteria	P	Heavy-metal-associated domain	copZ	-	-	-	-	-	-	-	-	-	-	-	HMA
MMS3_k127_3671763_0	351607.Acel_1652	4.951e-279	876.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4ERMQ@85013|Frankiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
MMS3_k127_3671763_4	1380390.JIAT01000010_gene3859	5.977e-21	108.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4CQM8@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
MMS3_k127_3671763_3	28444.JODQ01000001_gene2485	8.02e-77	274.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria,4EK8D@85012|Streptosporangiales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3671763_2	1283299.AUKG01000002_gene3898	5.482e-85	308.0	COG1316@1|root,COG1316@2|Bacteria,2HJ7K@201174|Actinobacteria,4CPJT@84995|Rubrobacteria	84995|Rubrobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
MMS3_k127_3671763_1	469383.Cwoe_0975	1.367e-86	303.0	COG0568@1|root,COG0568@2|Bacteria,2H445@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_3691511_6	329726.AM1_0723	1.424e-82	283.0	COG3555@1|root,COG3555@2|Bacteria,1G0W9@1117|Cyanobacteria	1117|Cyanobacteria	O	Aspartyl asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
MMS3_k127_3691511_0	1380390.JIAT01000010_gene4771	2.323e-241	768.0	COG2274@1|root,COG2274@2|Bacteria,2I2QC@201174|Actinobacteria,4CR1F@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_3691511_7	1122939.ATUD01000004_gene3924	6.33e-71	248.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4CQ34@84995|Rubrobacteria	84995|Rubrobacteria	S	Methyltransferase domain	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
MMS3_k127_3691511_3	469383.Cwoe_3471	1.31e-91	310.0	COG1073@1|root,COG1073@2|Bacteria,2I3YE@201174|Actinobacteria,4CRF0@84995|Rubrobacteria	84995|Rubrobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_3691511_5	1283299.AUKG01000002_gene4971	1.115e-87	297.0	COG2267@1|root,COG2267@2|Bacteria,2I0NW@201174|Actinobacteria,4CQPG@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_3691511_2	929712.KI912613_gene3888	4.646e-102	344.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CPGV@84995|Rubrobacteria	84995|Rubrobacteria	L	impB/mucB/samB family C-terminal domain	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
MMS3_k127_3691511_4	1380390.JIAT01000011_gene2633	8.851e-91	327.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,Trans_reg_C
MMS3_k127_3691511_1	1242864.D187_003204	1.737e-152	489.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,43EAF@68525|delta/epsilon subdivisions,2X34W@28221|Deltaproteobacteria,2YUA3@29|Myxococcales	28221|Deltaproteobacteria	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
MMS3_k127_3691511_8	1283299.AUKG01000002_gene4969	6.681e-37	148.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CQFM@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	-	-	-	-	-	-	-	-	-	DPBB_1
MMS3_k127_3699668_9	469383.Cwoe_1601	2.559e-18	87.0	COG1309@1|root,COG1309@2|Bacteria,2IEV2@201174|Actinobacteria,4CPWP@84995|Rubrobacteria	84995|Rubrobacteria	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
MMS3_k127_3699668_11	929712.KI912613_gene4871	7.156e-10	62.0	2A5U7@1|root,30UJT@2|Bacteria,2HRVK@201174|Actinobacteria,4CTZ1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3699668_7	1380390.JIAT01000011_gene2729	4.017e-31	135.0	2AWHM@1|root,31NE6@2|Bacteria,2HR07@201174|Actinobacteria,4CSTU@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
MMS3_k127_3699668_10	1283299.AUKG01000001_gene2795	5.403e-14	75.0	2AUM4@1|root,31K9W@2|Bacteria,2HP6Z@201174|Actinobacteria,4CQJ3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
MMS3_k127_3699668_2	1283299.AUKG01000001_gene2797	3.611e-111	366.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4CPTV@84995|Rubrobacteria	84995|Rubrobacteria	S	TIGRFAM degV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
MMS3_k127_3699668_5	469383.Cwoe_1610	4.6e-52	187.0	COG0278@1|root,COG0278@2|Bacteria,2HR8V@201174|Actinobacteria,4CT56@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
MMS3_k127_3699668_8	1380390.JIAT01000011_gene2739	2.415e-30	121.0	COG0271@1|root,COG0271@2|Bacteria,2HRA8@201174|Actinobacteria,4CT77@84995|Rubrobacteria	84995|Rubrobacteria	T	BolA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	BolA
MMS3_k127_3699668_4	1380390.JIAT01000011_gene2740	4.526e-53	189.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4CQFF@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
MMS3_k127_3699668_6	69014.TK0459	2.111e-50	194.0	COG1672@1|root,arCOG03169@2157|Archaea,2Y6A2@28890|Euryarchaeota,243U6@183968|Thermococci	183968|Thermococci	S	ATPase, AAA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2
MMS3_k127_3699668_3	1283299.AUKG01000001_gene2810	3.594e-58	209.0	COG0122@1|root,COG0122@2|Bacteria,2HGA7@201174|Actinobacteria,4CQF8@84995|Rubrobacteria	84995|Rubrobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_3699668_1	1380390.JIAT01000011_gene2743	1.042e-113	372.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4CQB7@84995|Rubrobacteria	84995|Rubrobacteria	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
MMS3_k127_3699668_0	469383.Cwoe_1613	2.529e-245	786.0	COG0392@1|root,COG0438@1|root,COG0392@2|Bacteria,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CPA3@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,LPG_synthase_TM
MMS3_k127_3717749_5	1380390.JIAT01000009_gene2226	2.922e-13	72.0	COG0451@1|root,COG0451@2|Bacteria,2HQUE@201174|Actinobacteria,4CSKY@84995|Rubrobacteria	84995|Rubrobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
MMS3_k127_3717749_3	929712.KI912613_gene4113	6.551e-48	193.0	COG1595@1|root,COG1595@2|Bacteria,2HQH3@201174|Actinobacteria,4CS25@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3717749_4	1123322.KB904655_gene596	1.024e-42	162.0	COG2020@1|root,COG2020@2|Bacteria,2IN0C@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMS3_k127_3717749_0	1122939.ATUD01000007_gene1942	4.123e-155	502.0	COG0208@1|root,COG3255@1|root,COG0208@2|Bacteria,COG3255@2|Bacteria,2GK48@201174|Actinobacteria,4CR5N@84995|Rubrobacteria	84995|Rubrobacteria	FI	Ribonucleotide reductase, small chain	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_red_sm,SCP2
MMS3_k127_3717749_2	1380390.JIAT01000010_gene3524	1.164e-58	214.0	COG0500@1|root,COG2226@2|Bacteria,2HPZV@201174|Actinobacteria,4CRFD@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMS3_k127_3717749_1	1283299.AUKG01000003_gene354	8.001e-97	332.0	COG3307@1|root,COG3307@2|Bacteria,2H5C0@201174|Actinobacteria,4CPXF@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,Wzy_C
MMS3_k127_3773606_13	469383.Cwoe_2415	0.0001134	55.0	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF1573,TIG,VCBS
MMS3_k127_3773606_12	1283299.AUKG01000003_gene184	3.743e-05	57.0	COG3291@1|root,COG3291@2|Bacteria,2I9UB@201174|Actinobacteria	201174|Actinobacteria	S	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	PASTA,PKD
MMS3_k127_3773606_3	512565.AMIS_48660	3.087e-113	376.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4DCA3@85008|Micromonosporales	201174|Actinobacteria	P	membrane protein terC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
MMS3_k127_3773606_7	1120960.ATXG01000005_gene2567	3.737e-25	115.0	COG3832@1|root,COG3832@2|Bacteria,2GTYS@201174|Actinobacteria,4FQD6@85023|Microbacteriaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMS3_k127_3773606_6	446468.Ndas_3347	4.415e-39	148.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4EKHG@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_3773606_10	1146883.BLASA_0141	2.432e-11	68.0	COG4118@1|root,COG4118@2|Bacteria,2GZW9@201174|Actinobacteria,4EWJT@85013|Frankiales	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
MMS3_k127_3773606_9	526225.Gobs_0797	1.521e-14	78.0	COG1848@1|root,COG1848@2|Bacteria,2GRA5@201174|Actinobacteria,4EVXY@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
MMS3_k127_3773606_4	1283299.AUKG01000004_gene980	7.817e-92	318.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CPTU@84995|Rubrobacteria	84995|Rubrobacteria	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
MMS3_k127_3773606_5	1283299.AUKG01000004_gene978	6.765e-83	282.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4CQ06@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_3773606_2	469383.Cwoe_3015	7.123e-154	510.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CPRI@84995|Rubrobacteria	84995|Rubrobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
MMS3_k127_3773606_11	1283299.AUKG01000004_gene973	2.54e-05	55.0	2AVII@1|root,31MB3@2|Bacteria,2HQ0D@201174|Actinobacteria,4CRG4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3773606_1	469383.Cwoe_3019	1.472e-159	518.0	COG0482@1|root,COG0822@1|root,COG0482@2|Bacteria,COG0822@2|Bacteria,2GIUQ@201174|Actinobacteria,4CPQ6@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	NifU_N,tRNA_Me_trans
MMS3_k127_3773606_0	469383.Cwoe_3034	8.604e-173	551.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CPQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
MMS3_k127_3820996_7	1380390.JIAT01000009_gene1907	8.81e-90	300.0	COG1131@1|root,COG1131@2|Bacteria,2H5DY@201174|Actinobacteria,4CSCC@84995|Rubrobacteria	84995|Rubrobacteria	V	ATPases associated with a variety of cellular activities	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
MMS3_k127_3820996_6	1380390.JIAT01000009_gene1911	1.269e-109	364.0	COG1648@1|root,COG1648@2|Bacteria,2GTES@201174|Actinobacteria,4CQK2@84995|Rubrobacteria	84995|Rubrobacteria	H	Sirohaem biosynthesis protein central	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
MMS3_k127_3820996_3	1283299.AUKG01000001_gene1885	9.669e-144	472.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
MMS3_k127_3820996_2	469383.Cwoe_5868	2.153e-158	512.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CPQ5@84995|Rubrobacteria	84995|Rubrobacteria	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
MMS3_k127_3820996_5	1380390.JIAT01000009_gene1882	1.407e-112	373.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CPDN@84995|Rubrobacteria	84995|Rubrobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
MMS3_k127_3820996_1	469383.Cwoe_5889	1.41e-159	538.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,4CPPP@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3820996_4	469383.Cwoe_5888	9.796e-130	422.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4CRBM@84995|Rubrobacteria	84995|Rubrobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_3820996_0	1440053.JOEI01000014_gene5195	8.76e-161	538.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMS3_k127_3820996_8	469383.Cwoe_5867	1.665e-18	91.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4CRVV@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3826275_18	1380390.JIAT01000016_gene5587	2.738e-57	205.0	COG0741@1|root,COG0741@2|Bacteria,2GWDB@201174|Actinobacteria,4CQ5G@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
MMS3_k127_3826275_17	469383.Cwoe_2873	2.678e-65	232.0	COG0237@1|root,COG0237@2|Bacteria,2HG2S@201174|Actinobacteria,4CQK0@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
MMS3_k127_3826275_2	1380390.JIAT01000016_gene5589	2.718e-196	626.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CPF8@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
MMS3_k127_3826275_6	469383.Cwoe_2871	9.932e-140	457.0	COG0644@1|root,COG0644@2|Bacteria,2HQ8K@201174|Actinobacteria,4CRS9@84995|Rubrobacteria	84995|Rubrobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3826275_8	1134445.AJJM01000003_gene3406	1.8e-116	391.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
MMS3_k127_3826275_20	1209984.BN978_02578	1.087e-26	115.0	297QE@1|root,2ZUXA@2|Bacteria,2IGMJ@201174|Actinobacteria,23A48@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3826275_19	47839.CCAU010000013_gene4679	1.525e-52	203.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,23511@1762|Mycobacteriaceae	201174|Actinobacteria	L	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_3826275_12	471853.Bcav_0264	2.201e-85	295.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_3826275_5	469383.Cwoe_1972	2.826e-148	474.0	28HGI@1|root,2Z9T0@2|Bacteria,2ICRF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3826275_0	1283299.AUKG01000004_gene1175	0.0	1127.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
MMS3_k127_3826275_1	1283299.AUKG01000004_gene1177	6.419e-218	688.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
MMS3_k127_3826275_9	1283299.AUKG01000004_gene1178	3.34e-106	355.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
MMS3_k127_3826275_14	1380390.JIAT01000016_gene5604	1.678e-84	295.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CPCG@84995|Rubrobacteria	84995|Rubrobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS3_k127_3826275_21	1283299.AUKG01000004_gene1188	5.82e-11	64.0	2A4BB@1|root,30SWZ@2|Bacteria,2HRP7@201174|Actinobacteria,4CTRH@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3826275_11	1283299.AUKG01000004_gene1189	1.024e-90	314.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4CPX0@84995|Rubrobacteria	84995|Rubrobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
MMS3_k127_3826275_3	469383.Cwoe_2859	1.553e-186	599.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4CP72@84995|Rubrobacteria	84995|Rubrobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_3826275_16	929712.KI912613_gene4379	6.545e-71	247.0	COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4CQBZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
MMS3_k127_3826275_10	1380390.JIAT01000016_gene5611	2.715e-101	345.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_3826275_15	1380390.JIAT01000016_gene5612	3.602e-76	271.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4CPUD@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the TrpC family	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
MMS3_k127_3826275_7	1380390.JIAT01000016_gene5613	9.465e-123	407.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CP6K@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
MMS3_k127_3826275_13	469383.Cwoe_2854	3.799e-85	286.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4CPX3@84995|Rubrobacteria	84995|Rubrobacteria	EH	Glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMS3_k127_3826275_4	469383.Cwoe_2853	1.261e-175	557.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CPNJ@84995|Rubrobacteria	84995|Rubrobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
MMS3_k127_3836391_5	1380390.JIAT01000010_gene3515	2.08e-111	377.0	COG0596@1|root,COG0596@2|Bacteria,2GNK7@201174|Actinobacteria,4CQZK@84995|Rubrobacteria	84995|Rubrobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
MMS3_k127_3836391_6	929712.KI912613_gene3067	1.907e-43	162.0	COG0251@1|root,COG0251@2|Bacteria,2IFCR@201174|Actinobacteria,4CSQ3@84995|Rubrobacteria	84995|Rubrobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
MMS3_k127_3836391_3	469383.Cwoe_4225	2.323e-222	702.0	COG0365@1|root,COG0365@2|Bacteria,2GJSQ@201174|Actinobacteria,4CRGY@84995|Rubrobacteria	84995|Rubrobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3836391_1	469383.Cwoe_4224	2.158e-226	710.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CP7A@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3836391_7	1380390.JIAT01000010_gene3548	2.483e-40	152.0	2BF3V@1|root,328W1@2|Bacteria,2HPA5@201174|Actinobacteria,4CQNE@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3836391_8	1283299.AUKG01000002_gene4333	1.088e-18	99.0	2AWUM@1|root,31NRV@2|Bacteria,2HRAH@201174|Actinobacteria,4CT7D@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3836391_4	1283299.AUKG01000002_gene4334	3.802e-167	530.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CSIF@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Succ_CoA_lig
MMS3_k127_3836391_2	1380390.JIAT01000010_gene3561	2.722e-225	703.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CRQG@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2
MMS3_k127_3836391_0	1120936.KB907215_gene3950	6.649e-300	953.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
MMS3_k127_3840311_2	1380390.JIAT01000001_gene5046	2.08e-25	108.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4CRKQ@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_3840311_1	469383.Cwoe_4559	1.931e-123	412.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4CRVP@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3840311_0	1380390.JIAT01000001_gene5029	4.152e-273	857.0	COG0300@1|root,COG3320@1|root,COG0300@2|Bacteria,COG3320@2|Bacteria,2GJ1R@201174|Actinobacteria,4CR82@84995|Rubrobacteria	84995|Rubrobacteria	Q	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
MMS3_k127_3840311_3	1380390.JIAT01000001_gene5028	1.175e-15	77.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4CS7T@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_3848002_4	469383.Cwoe_0770	8.476e-19	87.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4CQ70@84995|Rubrobacteria	84995|Rubrobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
MMS3_k127_3848002_3	469383.Cwoe_0769	1.148e-24	108.0	2B9V4@1|root,32383@2|Bacteria,2HRXS@201174|Actinobacteria,4CU12@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3848002_0	469383.Cwoe_0768	6.35e-195	619.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CPRJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_3848002_2	469383.Cwoe_0767	1.63e-42	163.0	COG3917@1|root,COG3917@2|Bacteria,2HPTQ@201174|Actinobacteria,4CR7K@84995|Rubrobacteria	84995|Rubrobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
MMS3_k127_3848002_1	1382306.JNIM01000001_gene940	1.583e-92	312.0	COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi	200795|Chloroflexi	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMS3_k127_3882589_19	469383.Cwoe_3707	1.137e-60	215.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4CQB8@84995|Rubrobacteria	84995|Rubrobacteria	H	riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
MMS3_k127_3882589_7	1380390.JIAT01000010_gene4209	2.326e-173	550.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4CQ5P@84995|Rubrobacteria	84995|Rubrobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
MMS3_k127_3882589_17	469383.Cwoe_1770	1.215e-70	249.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRAY@84995|Rubrobacteria	201174|Actinobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
MMS3_k127_3882589_9	1380390.JIAT01000009_gene1778	1.941e-158	514.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CPCV@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
MMS3_k127_3882589_20	469383.Cwoe_3660	1.959e-55	196.0	COG0328@1|root,COG0328@2|Bacteria,2I4IN@201174|Actinobacteria	201174|Actinobacteria	L	Reverse transcriptase-like	-	-	3.1.26.4,3.1.3.73	ko:K03469,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	Glyoxalase_4,His_Phos_1,RVT_3
MMS3_k127_3882589_28	1283299.AUKG01000002_gene4776	9.702e-12	70.0	2B9E0@1|root,322RT@2|Bacteria,2HRVF@201174|Actinobacteria,4CTYV@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3882589_26	1380390.JIAT01000010_gene4284	3.506e-17	92.0	2AT5U@1|root,31IN3@2|Bacteria,2HN2Z@201174|Actinobacteria,4CQH5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3882589_10	469383.Cwoe_1889	2.054e-153	501.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CQTJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
MMS3_k127_3882589_13	1380390.JIAT01000014_gene6080	3.075e-107	370.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CP9P@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
MMS3_k127_3882589_8	469383.Cwoe_1886	1.586e-158	518.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CPXV@84995|Rubrobacteria	84995|Rubrobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
MMS3_k127_3882589_1	469383.Cwoe_1884	2.568e-280	874.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4CPJN@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
MMS3_k127_3882589_6	1283299.AUKG01000001_gene3198	1.182e-181	580.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CP8E@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_3882589_18	1380390.JIAT01000014_gene6086	3.67e-66	244.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CQGC@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
MMS3_k127_3882589_16	469383.Cwoe_1881	3.06e-73	249.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CQAX@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
MMS3_k127_3882589_0	469383.Cwoe_1875	1.96e-286	889.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CPPY@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
MMS3_k127_3882589_5	469383.Cwoe_1874	6.965e-205	642.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CP9K@84995|Rubrobacteria	84995|Rubrobacteria	F	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
MMS3_k127_3882589_4	469383.Cwoe_1538	3.425e-238	762.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CPVB@84995|Rubrobacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
MMS3_k127_3882589_14	1313265.JNIE01000004_gene589	1.989e-98	343.0	COG0498@1|root,COG0498@2|Bacteria,2G4SE@200783|Aquificae	200783|Aquificae	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC_1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_3882589_24	1255043.TVNIR_1089	2.893e-19	91.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,1SJ4Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
MMS3_k127_3882589_3	469383.Cwoe_3508	4.587e-250	799.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CR6V@84995|Rubrobacteria	84995|Rubrobacteria	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
MMS3_k127_3882589_12	345341.KUTG_01324	4.17e-108	365.0	COG4934@1|root,COG4934@2|Bacteria,2HETA@201174|Actinobacteria,4E9CK@85010|Pseudonocardiales	201174|Actinobacteria	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3882589_21	525368.HMPREF0591_4503	3.986e-48	179.0	COG1487@1|root,COG1487@2|Bacteria,2IS29@201174|Actinobacteria,23BI2@1762|Mycobacteriaceae	201174|Actinobacteria	S	PIN domain	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
MMS3_k127_3882589_22	350058.Mvan_1709	4.073e-31	123.0	COG4691@1|root,COG4691@2|Bacteria,2HYH5@201174|Actinobacteria,23E5Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	Ribbon-helix-helix protein, copG family	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	RHH_1
MMS3_k127_3882589_27	1484460.JSWG01000007_gene3140	4.889e-12	73.0	2DZVD@1|root,32VJZ@2|Bacteria,4NUB2@976|Bacteroidetes,1I482@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
MMS3_k127_3882589_15	1283299.AUKG01000002_gene4280	3.02e-98	325.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CQK7@84995|Rubrobacteria	84995|Rubrobacteria	K	LexA DNA binding domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
MMS3_k127_3882589_25	1123024.AUII01000010_gene715	1.532e-17	96.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4E5U9@85010|Pseudonocardiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS3_k127_3882589_30	314254.OA2633_08604	5.79e-07	59.0	COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,2V9QG@28211|Alphaproteobacteria,43ZVI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
MMS3_k127_3882589_11	1122939.ATUD01000005_gene2562	1.377e-135	444.0	COG2837@1|root,COG2837@2|Bacteria,2GIUB@201174|Actinobacteria,4CP9V@84995|Rubrobacteria	84995|Rubrobacteria	P	Dyp-type peroxidase family	-	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox
MMS3_k127_3882589_2	134676.ACPL_5842	3.31e-256	868.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TIG
MMS3_k127_3882589_23	1380390.JIAT01000010_gene4266	2.937e-27	132.0	COG4733@1|root,COG4733@2|Bacteria,2I7QH@201174|Actinobacteria,4CS4B@84995|Rubrobacteria	84995|Rubrobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3899188_4	469383.Cwoe_5875	5.871e-77	264.0	COG2386@1|root,COG2386@2|Bacteria,2GUCP@201174|Actinobacteria,4CQ9M@84995|Rubrobacteria	84995|Rubrobacteria	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
MMS3_k127_3899188_3	1380390.JIAT01000009_gene1905	2.746e-82	280.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria,4CSM2@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
MMS3_k127_3899188_2	1283299.AUKG01000001_gene1871	8.609e-176	561.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CPKE@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
MMS3_k127_3899188_5	469383.Cwoe_5879	1.468e-75	283.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4CQ8E@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
MMS3_k127_3899188_1	469383.Cwoe_5880	3.837e-191	613.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GK3B@201174|Actinobacteria,4CPJJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
MMS3_k127_3899188_6	1380390.JIAT01000009_gene1898	4.541e-73	253.0	COG0340@1|root,COG0340@2|Bacteria,2HGFP@201174|Actinobacteria,4CQNA@84995|Rubrobacteria	84995|Rubrobacteria	H	biotin lipoate A B protein ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
MMS3_k127_3899188_0	469383.Cwoe_5882	0.0	1189.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4CPIG@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
MMS3_k127_3899188_7	469383.Cwoe_5885	6.103e-42	159.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CRCP@84995|Rubrobacteria	84995|Rubrobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
MMS3_k127_400690_6	1122939.ATUD01000003_gene3521	5.293e-54	203.0	COG2197@1|root,COG2197@2|Bacteria,2IIZS@201174|Actinobacteria,4CRXE@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_400690_4	1283299.AUKG01000001_gene2404	4.189e-65	237.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4CRWF@84995|Rubrobacteria	84995|Rubrobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
MMS3_k127_400690_7	1523503.JPMY01000042_gene2922	5.565e-08	62.0	COG2199@1|root,COG3706@2|Bacteria,1R7HR@1224|Proteobacteria,1S1JF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMS3_k127_400690_1	469383.Cwoe_3083	1.172e-144	485.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,4CQX8@84995|Rubrobacteria	84995|Rubrobacteria	S	Thiamin pyrophosphokinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
MMS3_k127_400690_5	469383.Cwoe_3084	2.541e-56	207.0	28JWD@1|root,30ITI@2|Bacteria,2HRPM@201174|Actinobacteria,4CTRY@84995|Rubrobacteria	84995|Rubrobacteria	S	Copper transport outer membrane protein, MctB	-	-	-	-	-	-	-	-	-	-	-	-	MctB
MMS3_k127_400690_3	469383.Cwoe_3085	8.166e-77	266.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria,4CTZJ@84995|Rubrobacteria	84995|Rubrobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_400690_0	469383.Cwoe_3086	6.461e-270	840.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CPN2@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
MMS3_k127_400690_8	1380390.JIAT01000003_gene5453	0.0001591	47.0	COG2195@1|root,COG2195@2|Bacteria,2HPTW@201174|Actinobacteria,4CR7V@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_400690_2	469383.Cwoe_3088	1.485e-115	383.0	COG3502@1|root,COG3502@2|Bacteria,2H2JJ@201174|Actinobacteria,4CTCT@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
MMS3_k127_4080423_10	1268622.AVS7_02360	0.0003573	48.0	2CD16@1|root,339EE@2|Bacteria,1ND6N@1224|Proteobacteria,2VXDW@28216|Betaproteobacteria,4AFPJ@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4080423_9	1123024.AUII01000007_gene4839	1.56e-05	51.0	COG3620@1|root,COG3620@2|Bacteria,2GTMF@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMS3_k127_4080423_8	208439.AJAP_02935	8.833e-14	80.0	2DQQK@1|root,33842@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
MMS3_k127_4080423_6	68223.JNZY01000076_gene7453	4.16e-23	112.0	29YC4@1|root,30K6H@2|Bacteria,2H0Z2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4080423_4	298654.FraEuI1c_0427	2.25e-62	226.0	COG0346@1|root,COG0346@2|Bacteria,2IS2C@201174|Actinobacteria,4EWD7@85013|Frankiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_4080423_0	1120950.KB892804_gene1473	7.588e-105	364.0	COG0642@1|root,COG0642@2|Bacteria,2I436@201174|Actinobacteria,4DWI7@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_4080423_1	103733.JNYO01000051_gene6609	5.807e-102	337.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4E36D@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_4080423_5	1122611.KB903940_gene1928	2.947e-56	199.0	COG1725@1|root,COG1725@2|Bacteria,2IHTD@201174|Actinobacteria,4EIYZ@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
MMS3_k127_4080423_7	390989.JOEG01000028_gene5486	7.374e-21	105.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4D905@85008|Micromonosporales	201174|Actinobacteria	V	COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_4080423_2	208439.AJAP_32475	7.67e-73	253.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4DZ3W@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_4080423_3	1380347.JNII01000007_gene292	3.484e-69	252.0	COG1277@1|root,COG1277@2|Bacteria,2GM0N@201174|Actinobacteria,4EVKG@85013|Frankiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_4083548_11	754035.Mesau_00202	4.091e-19	94.0	COG3600@1|root,COG3600@2|Bacteria	2|Bacteria	K	Phage-associated protein	gepA	-	-	-	-	-	-	-	-	-	-	-	DUF4065,MqsA_antitoxin
MMS3_k127_4083548_9	1451261.AS96_03215	5.523e-26	111.0	COG1487@1|root,COG1487@2|Bacteria,2IN9Z@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_4083548_6	1075090.GOAMR_76_00560	1.784e-58	211.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria,4GGRX@85026|Gordoniaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
MMS3_k127_4083548_2	1380390.JIAT01000009_gene1313	3.101e-83	296.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Beta_helix,CBM_6,Cellulase,DUF1573,DUF4978,F5_F8_type_C,Laminin_G_3,Pectate_lyase_3,RicinB_lectin_2
MMS3_k127_4083548_8	287986.DV20_24400	2.964e-27	127.0	COG0463@1|root,COG0463@2|Bacteria,2GM44@201174|Actinobacteria,4E1XM@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_4083548_7	929712.KI912613_gene454	1.978e-39	167.0	2AVU4@1|root,31MMQ@2|Bacteria,2HQAN@201174|Actinobacteria,4CRUS@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4083548_1	929712.KI912613_gene2536	5.359e-151	492.0	COG0451@1|root,COG0451@2|Bacteria,2GPN0@201174|Actinobacteria	201174|Actinobacteria	M	Nad-dependent epimerase dehydratase	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
MMS3_k127_4083548_0	326424.FRAAL3336	3.215e-164	527.0	COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria	201174|Actinobacteria	J	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS3_k127_4083548_4	469383.Cwoe_3157	1.03e-66	234.0	COG1898@1|root,COG1898@2|Bacteria,2GMW4@201174|Actinobacteria,4CQ10@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
MMS3_k127_4083548_10	497964.CfE428DRAFT_0862	4.27e-25	113.0	COG2091@1|root,COG2091@2|Bacteria,46T3D@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
MMS3_k127_4083548_3	469383.Cwoe_5475	3.134e-70	256.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4CRU2@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
MMS3_k127_4083548_13	745014.OMB55_00010360	5.032e-18	87.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1J6K6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMS3_k127_4083548_5	469383.Cwoe_0136	8.195e-66	235.0	COG0726@1|root,COG0726@2|Bacteria,2H6C7@201174|Actinobacteria,4CRGB@84995|Rubrobacteria	84995|Rubrobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_4149999_1	1283299.AUKG01000002_gene4895	2.411e-200	632.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CP8S@84995|Rubrobacteria	84995|Rubrobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
MMS3_k127_4149999_3	469383.Cwoe_3543	1.836e-75	260.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4CQEI@84995|Rubrobacteria	84995|Rubrobacteria	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
MMS3_k127_4149999_0	1380390.JIAT01000010_gene4505	1.02e-203	663.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
MMS3_k127_4149999_2	469383.Cwoe_3541	1.023e-157	507.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CPR4@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
MMS3_k127_4149999_5	1329516.JPST01000070_gene1945	2.62e-15	78.0	2ERMT@1|root,33J79@2|Bacteria,1VKZE@1239|Firmicutes,4I01W@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4159398_1	1283299.AUKG01000001_gene2083	2.676e-93	331.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4159398_2	1283299.AUKG01000002_gene3750	3.47e-52	197.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,GGDEF
MMS3_k127_4159398_0	1380390.JIAT01000009_gene1327	0.0	1314.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CPJQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMS3_k127_4159398_3	1380390.JIAT01000009_gene1324	1.003e-05	51.0	COG1363@1|root,COG1363@2|Bacteria,2ID5X@201174|Actinobacteria,4CP5U@84995|Rubrobacteria	84995|Rubrobacteria	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
MMS3_k127_4234004_2	929712.KI912613_gene90	1.707e-16	92.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TIR_2
MMS3_k127_4234004_0	1283299.AUKG01000002_gene4966	5.955e-196	629.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_4234004_1	469383.Cwoe_3480	1.156e-118	391.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
MMS3_k127_4279864_9	929712.KI912613_gene3438	3.504e-11	70.0	COG2165@1|root,COG2165@2|Bacteria,2GTN8@201174|Actinobacteria,4CQSF@84995|Rubrobacteria	84995|Rubrobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
MMS3_k127_4279864_10	1380390.JIAT01000017_gene5286	9.545e-09	59.0	2AXDB@1|root,31PCN@2|Bacteria,2HRSW@201174|Actinobacteria,4CTW4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4279864_5	929712.KI912613_gene1383	7.909e-100	349.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,4CRS1@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_4279864_4	1283299.AUKG01000004_gene956	2.697e-126	421.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CPCS@84995|Rubrobacteria	84995|Rubrobacteria	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
MMS3_k127_4279864_2	1380390.JIAT01000017_gene5296	9.721e-160	516.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4CPUI@84995|Rubrobacteria	84995|Rubrobacteria	NU	COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
MMS3_k127_4279864_1	1380390.JIAT01000017_gene5297	3.522e-171	545.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMS3_k127_4279864_0	929712.KI912613_gene3421	1.326e-182	591.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria,4CPMS@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
MMS3_k127_4279864_6	1283299.AUKG01000004_gene968	4.181e-79	282.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CQ8W@84995|Rubrobacteria	84995|Rubrobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
MMS3_k127_4279864_7	929712.KI912613_gene3419	1.667e-60	222.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CQ8A@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
MMS3_k127_4279864_8	1283299.AUKG01000004_gene970	1.512e-41	156.0	COG0816@1|root,COG0816@2|Bacteria,2HPE8@201174|Actinobacteria,4CQSC@84995|Rubrobacteria	84995|Rubrobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
MMS3_k127_4279864_3	469383.Cwoe_3034	8.517e-142	463.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CPQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
MMS3_k127_4305833_0	1122939.ATUD01000001_gene35	2.072e-30	126.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
MMS3_k127_4305833_5	1144275.COCOR_00828	4.219e-08	60.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMS3_k127_4305833_2	419947.MRA_2850	2.705e-22	109.0	COG2253@1|root,COG2253@2|Bacteria,2IHAS@201174|Actinobacteria,23E07@1762|Mycobacteriaceae	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	ko:K09144	-	-	-	-	ko00000	-	-	-	AbiEii
MMS3_k127_4305833_4	1227457.C451_03244	7.527e-10	69.0	COG5340@1|root,arCOG04793@2157|Archaea,2XVVB@28890|Euryarchaeota,23UHQ@183963|Halobacteria	183963|Halobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
MMS3_k127_4305833_1	1283299.AUKG01000002_gene4915	1.752e-27	120.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
MMS3_k127_478779_1	1380390.JIAT01000009_gene2022	5.338e-99	336.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4CPF7@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS3_k127_478779_0	1380390.JIAT01000009_gene2025	1.977e-185	592.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria,4CPP8@84995|Rubrobacteria	84995|Rubrobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_478779_3	656024.FsymDg_3543	2.721e-43	164.0	COG4636@1|root,COG4636@2|Bacteria,2H9N5@201174|Actinobacteria	201174|Actinobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
MMS3_k127_478779_4	1206729.BAFZ01000100_gene5946	1.436e-09	68.0	COG1309@1|root,COG1309@2|Bacteria,2IP2Y@201174|Actinobacteria,4G2GW@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_478779_2	1496688.ER33_11575	1.793e-96	331.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
MMS3_k127_510597_2	351607.Acel_1820	1.046e-150	484.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4ES6V@85013|Frankiales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase (Decarboxylating)	gnd2	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1122	6PGD,NAD_binding_2
MMS3_k127_510597_0	994479.GL877882_gene6710	2.207e-266	837.0	COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4EACZ@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
MMS3_k127_510597_6	469383.Cwoe_3692	2.345e-17	85.0	COG0333@1|root,COG0333@2|Bacteria,2HPDQ@201174|Actinobacteria,4CQRN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
MMS3_k127_510597_3	1283299.AUKG01000001_gene2689	6.716e-116	383.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria,4CPK4@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
MMS3_k127_510597_5	1283299.AUKG01000001_gene2690	1.074e-49	181.0	2B899@1|root,321HW@2|Bacteria,2HP5C@201174|Actinobacteria,4CQHB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_510597_1	469383.Cwoe_1388	1.974e-260	816.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CPFF@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
MMS3_k127_510597_4	469383.Cwoe_4390	1.346e-80	278.0	COG0327@1|root,COG0327@2|Bacteria,2HQUS@201174|Actinobacteria,4CSMH@84995|Rubrobacteria	84995|Rubrobacteria	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
MMS3_k127_514150_6	243231.GSU2436	1.29e-112	374.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42MBM@68525|delta/epsilon subdivisions,2WJKG@28221|Deltaproteobacteria,43S8T@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Transketolase central region	pdhB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2753	Transket_pyr,Transketolase_C
MMS3_k127_514150_5	469383.Cwoe_2774	1.489e-120	405.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4CPDS@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_514150_8	469383.Cwoe_0744	7.396e-69	244.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4CQ38@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
MMS3_k127_514150_2	469383.Cwoe_0743	1.674e-165	533.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
MMS3_k127_514150_7	1380390.JIAT01000009_gene1570	1.506e-83	292.0	COG1686@1|root,COG1686@2|Bacteria,2GK3M@201174|Actinobacteria,4CPMV@84995|Rubrobacteria	84995|Rubrobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
MMS3_k127_514150_1	1283299.AUKG01000001_gene1515	5.831e-200	629.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria,4CP5V@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_514150_3	469383.Cwoe_0735	1.699e-131	433.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4CPSN@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
MMS3_k127_514150_9	1380390.JIAT01000012_gene3262	1.572e-34	149.0	2AW01@1|root,31MUG@2|Bacteria,2HQH6@201174|Actinobacteria,4CS28@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_514150_4	266117.Rxyl_0048	1.667e-128	421.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CSJN@84995|Rubrobacteria	84995|Rubrobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
MMS3_k127_514150_0	42256.RradSPS_3020	6.081e-261	820.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CPE7@84995|Rubrobacteria	84995|Rubrobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
MMS3_k127_514150_11	469383.Cwoe_3152	4.907e-24	117.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_514150_10	469383.Cwoe_3167	3.68e-24	117.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_514150_12	929712.KI912613_gene3029	1.112e-10	64.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS3_k127_566007_0	469383.Cwoe_5426	0.0	1528.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CP7K@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
MMS3_k127_566007_28	469383.Cwoe_5424	7.631e-06	57.0	2AXAR@1|root,31P9U@2|Bacteria,2HRQT@201174|Actinobacteria,4CTT6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_566007_12	1122939.ATUD01000025_gene2543	6.5e-60	232.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CQ6G@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
MMS3_k127_566007_9	469383.Cwoe_5416	1.966e-92	324.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4CQDV@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
MMS3_k127_566007_7	1380390.JIAT01000009_gene2263	7.743e-101	336.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4CPKG@84995|Rubrobacteria	84995|Rubrobacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
MMS3_k127_566007_26	751945.Theos_1927	3.119e-11	73.0	2CNM1@1|root,33GE6@2|Bacteria,1WJRK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
MMS3_k127_566007_3	469383.Cwoe_3741	2.561e-183	593.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CPUN@84995|Rubrobacteria	84995|Rubrobacteria	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C
MMS3_k127_566007_20	768671.ThimaDRAFT_0960	6.545e-31	128.0	2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria,1THVW@1236|Gammaproteobacteria,1WZR5@135613|Chromatiales	135613|Chromatiales	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
MMS3_k127_566007_25	264462.Bd2770	4.33e-13	75.0	2DWY1@1|root,342G1@2|Bacteria,1N2NN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_566007_6	1283299.AUKG01000001_gene1614	2.04e-113	391.0	2CE4Q@1|root,2Z7WX@2|Bacteria,2H0P6@201174|Actinobacteria,4CRA3@84995|Rubrobacteria	201174|Actinobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
MMS3_k127_566007_4	1380390.JIAT01000002_gene6003	6.728e-118	415.0	COG0477@1|root,COG0477@2|Bacteria,2HF4N@201174|Actinobacteria,4CPRZ@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_566007_5	1382356.JQMP01000003_gene1765	1.523e-116	398.0	COG3118@1|root,COG3118@2|Bacteria,2G8FS@200795|Chloroflexi	200795|Chloroflexi	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
MMS3_k127_566007_1	357808.RoseRS_2091	1.376e-282	885.0	COG0145@1|root,COG0145@2|Bacteria	2|Bacteria	EQ	ligase activity	oplaH	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
MMS3_k127_566007_2	383372.Rcas_1777	3.024e-240	781.0	COG0146@1|root,COG0146@2|Bacteria	2|Bacteria	EQ	ligase activity	hyuB	-	3.5.2.14,6.4.1.6	ko:K01474,ko:K10854	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_566007_17	562970.Btus_2467	4.828e-41	176.0	COG4647@1|root,COG4647@2|Bacteria,1TTB5@1239|Firmicutes,4HCXE@91061|Bacilli,2794U@186823|Alicyclobacillaceae	91061|Bacilli	Q	Acetone carboxylase gamma subunit	-	-	6.4.1.6	ko:K10856	-	-	-	-	ko00000,ko01000	-	-	-	Acetone_carb_G
MMS3_k127_566007_23	1123023.JIAI01000013_gene3988	1.601e-23	106.0	COG1848@1|root,COG1848@2|Bacteria,2HDIZ@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_566007_27	469383.Cwoe_3733	4.96e-07	55.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,MazE_antitoxin
MMS3_k127_566007_15	1211035.CD30_04110	2.089e-47	191.0	29MNG@1|root,308K7@2|Bacteria,1VTU1@1239|Firmicutes,4HTYB@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_566007_10	196162.Noca_4966	1.284e-87	316.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_566007_19	67281.JNZZ01000007_gene5046	4.535e-33	141.0	COG0583@1|root,COG0583@2|Bacteria,2GMES@201174|Actinobacteria,418AR@629295|Streptomyces griseus group	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_566007_13	1380390.JIAT01000012_gene3184	1.43e-59	231.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4CPBG@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
MMS3_k127_566007_14	1283299.AUKG01000006_gene754	6.269e-49	187.0	2AWR3@1|root,31NN1@2|Bacteria,2HR71@201174|Actinobacteria,4CT2W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_566007_21	1121372.AULK01000019_gene1796	2.275e-30	129.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
MMS3_k127_566007_22	469383.Cwoe_3961	4.573e-27	115.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
MMS3_k127_566007_24	1163617.SCD_n01379	1.101e-15	87.0	COG1669@1|root,COG1669@2|Bacteria,1N9WC@1224|Proteobacteria,2VY03@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
MMS3_k127_566007_8	266117.Rxyl_0594	3.456e-97	328.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CPWR@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
MMS3_k127_566007_18	469383.Cwoe_4984	4.516e-36	143.0	COG0640@1|root,COG0640@2|Bacteria,2IMIV@201174|Actinobacteria,4CQJJ@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein, arsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
MMS3_k127_566007_16	649638.Trad_2723	4.961e-44	173.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
MMS3_k127_566007_11	1283299.AUKG01000001_gene1398	1.531e-73	253.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4CQD7@84995|Rubrobacteria	84995|Rubrobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
MMS3_k127_581298_5	525368.HMPREF0591_2708	5.156e-47	171.0	COG5470@1|root,COG5470@2|Bacteria,2IM3I@201174|Actinobacteria,239HM@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
MMS3_k127_581298_6	1440774.Y900_004625	4.749e-39	155.0	COG1309@1|root,COG1309@2|Bacteria,2IDJT@201174|Actinobacteria,239JZ@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_581298_0	557599.MKAN_25710	6.45e-307	951.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,234PM@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_581298_2	95619.PM1_0222350	1.31e-66	236.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	ptlF	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_581298_4	1313172.YM304_34220	3.6e-51	190.0	COG0346@1|root,COG0346@2|Bacteria,2H7KR@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
MMS3_k127_581298_1	1313172.YM304_38280	1.448e-88	310.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CNT1@84992|Acidimicrobiia	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_581298_3	1313172.YM304_38290	7.452e-62	220.0	COG0577@1|root,COG0577@2|Bacteria,2GMC4@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	hrtB	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_687903_1	469383.Cwoe_5826	2.778e-113	371.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
MMS3_k127_687903_0	929712.KI912613_gene3421	4.967e-153	518.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria,4CPMS@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
MMS3_k127_687903_11	42256.RradSPS_1978	5.697e-09	61.0	COG1826@1|root,COG1826@2|Bacteria,2HRTJ@201174|Actinobacteria,4CTX0@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_687903_9	1283299.AUKG01000001_gene1967	1.776e-26	119.0	COG0730@1|root,COG0730@2|Bacteria,2HU3V@201174|Actinobacteria,4CTHN@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
MMS3_k127_687903_8	1283299.AUKG01000001_gene1966	1.076e-34	138.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_687903_3	469383.Cwoe_5832	1.281e-93	315.0	COG1877@1|root,COG1877@2|Bacteria,2HP2R@201174|Actinobacteria,4CQDQ@84995|Rubrobacteria	84995|Rubrobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
MMS3_k127_687903_6	1283299.AUKG01000001_gene1964	3.498e-55	198.0	2AUAQ@1|root,31JYC@2|Bacteria,2HNZD@201174|Actinobacteria,4CQ8V@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_687903_2	1380390.JIAT01000009_gene1991	2.677e-102	345.0	COG0438@1|root,COG0438@2|Bacteria,2HNS0@201174|Actinobacteria,4CPZG@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_687903_10	83332.Rv0582	1.208e-22	103.0	COG2402@1|root,COG2402@2|Bacteria,2HZHQ@201174|Actinobacteria,23BTY@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
MMS3_k127_687903_4	1206720.BAFQ01000049_gene1172	2.056e-79	272.0	COG0412@1|root,COG0412@2|Bacteria,2GJMH@201174|Actinobacteria,4FVWA@85025|Nocardiaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	cmbl	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS3_k127_687903_5	1380390.JIAT01000010_gene4594	1.28e-62	230.0	COG3917@1|root,COG3917@2|Bacteria,2HQ7I@201174|Actinobacteria,4CRQP@84995|Rubrobacteria	84995|Rubrobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_687903_7	479434.Sthe_2963	6.773e-50	184.0	COG0262@1|root,COG0262@2|Bacteria,2G77E@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMS3_k127_693364_16	419947.MRA_2520	1.226e-59	210.0	COG1848@1|root,COG1848@2|Bacteria,2GVWT@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
MMS3_k127_693364_24	419947.MRA_2519	6.247e-30	119.0	2DPH3@1|root,33224@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_693364_22	446470.Snas_1444	7.011e-35	140.0	COG1848@1|root,COG1848@2|Bacteria,2GVQ7@201174|Actinobacteria,4F00V@85014|Glycomycetales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
MMS3_k127_693364_13	1379270.AUXF01000001_gene2443	1.357e-119	397.0	COG1819@1|root,COG1819@2|Bacteria	2|Bacteria	CG	transferase activity, transferring hexosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
MMS3_k127_693364_21	196162.Noca_2965	2.999e-37	147.0	COG1309@1|root,COG1309@2|Bacteria,2IR68@201174|Actinobacteria,4DV32@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_693364_3	469383.Cwoe_5621	1.898e-172	570.0	COG4591@1|root,COG4591@2|Bacteria,2I6IU@201174|Actinobacteria	201174|Actinobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_693364_14	469383.Cwoe_3648	1.998e-79	271.0	COG1136@1|root,COG1136@2|Bacteria,2GNB3@201174|Actinobacteria,4CU2E@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_693364_29	1283299.AUKG01000001_gene3246	7.539e-14	83.0	2AW75@1|root,31N27@2|Bacteria,2HQQH@201174|Actinobacteria,4CSDA@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_693364_23	521393.JH806632_gene1104	4.128e-34	138.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
MMS3_k127_693364_32	525368.HMPREF0591_0627	2.173e-08	61.0	2BA8Y@1|root,323P2@2|Bacteria,2H8D9@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
MMS3_k127_693364_20	469383.Cwoe_1077	1.653e-39	150.0	2AUHF@1|root,31K5S@2|Bacteria,2HP4J@201174|Actinobacteria,4CQG4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_693364_12	469383.Cwoe_1078	1.382e-120	405.0	COG0491@1|root,COG5485@1|root,COG0491@2|Bacteria,COG5485@2|Bacteria,2HNVQ@201174|Actinobacteria,4CTIR@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_693364_5	1380390.JIAT01000009_gene1245	2.855e-132	433.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4CPAG@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_693364_8	1380390.JIAT01000009_gene1244	1.547e-124	404.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CRD2@84995|Rubrobacteria	84995|Rubrobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
MMS3_k127_693364_26	555079.Toce_2178	7.376e-21	98.0	COG1708@1|root,COG1708@2|Bacteria,1VM1R@1239|Firmicutes,24UG9@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
MMS3_k127_693364_17	469383.Cwoe_1084	2.857e-58	207.0	COG1451@1|root,COG1451@2|Bacteria,2HQ1W@201174|Actinobacteria,4CRI6@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
MMS3_k127_693364_1	1380390.JIAT01000009_gene1231	6.488e-222	695.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_693364_9	469383.Cwoe_1095	1.265e-121	418.0	COG0524@1|root,COG0524@2|Bacteria,2HPJD@201174|Actinobacteria,4CQWU@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
MMS3_k127_693364_7	469383.Cwoe_1096	1.431e-124	424.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4CPSU@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_693364_2	1283299.AUKG01000003_gene218	2.671e-211	670.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CP81@84995|Rubrobacteria	84995|Rubrobacteria	L	DbpA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DbpA,Helicase_C
MMS3_k127_693364_15	469383.Cwoe_1100	7.739e-73	247.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CQGA@84995|Rubrobacteria	84995|Rubrobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
MMS3_k127_693364_0	469383.Cwoe_1105	1.376e-229	721.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4CPPX@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10	ko:K00135,ko:K22445	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_693364_10	1382356.JQMP01000003_gene1765	1.354e-121	413.0	COG3118@1|root,COG3118@2|Bacteria,2G8FS@200795|Chloroflexi	200795|Chloroflexi	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
MMS3_k127_693364_19	1283299.AUKG01000003_gene238	5.732e-58	209.0	COG1011@1|root,COG1011@2|Bacteria,2HP8G@201174|Actinobacteria,4CQKJ@84995|Rubrobacteria	84995|Rubrobacteria	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS3_k127_693364_4	1283299.AUKG01000003_gene239	4.002e-157	504.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4CR5Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_693364_11	1380390.JIAT01000009_gene1198	1.536e-121	407.0	COG2723@1|root,COG2723@2|Bacteria,2HNUQ@201174|Actinobacteria,4CQ33@84995|Rubrobacteria	84995|Rubrobacteria	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_693364_6	469383.Cwoe_1111	7.227e-125	405.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4CPDC@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
MMS3_k127_693364_25	555079.Toce_2178	2.064e-25	109.0	COG1708@1|root,COG1708@2|Bacteria,1VM1R@1239|Firmicutes,24UG9@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
MMS3_k127_693364_27	469383.Cwoe_3961	3.197e-18	93.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
MMS3_k127_693364_18	1380390.JIAT01000009_gene1191	2.964e-58	207.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4CQMC@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS3_k127_709746_25	1380390.JIAT01000010_gene4503	2.629e-19	88.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CP8S@84995|Rubrobacteria	84995|Rubrobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
MMS3_k127_709746_8	469383.Cwoe_3545	1.574e-171	546.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4CR4P@84995|Rubrobacteria	84995|Rubrobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_709746_4	929712.KI912613_gene3937	5.869e-213	674.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CPIA@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMS3_k127_709746_11	1380390.JIAT01000010_gene4499	7.086e-161	511.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CPCQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_709746_10	1380390.JIAT01000010_gene4498	1.365e-164	524.0	COG0473@1|root,COG0473@2|Bacteria,2HABY@201174|Actinobacteria,4CPBV@84995|Rubrobacteria	84995|Rubrobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS3_k127_709746_20	1380390.JIAT01000010_gene4495	2.472e-76	261.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CQ8R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
MMS3_k127_709746_24	1496688.ER33_10345	2.434e-30	131.0	COG0500@1|root,COG2226@2|Bacteria,1G1SP@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS3_k127_709746_2	469383.Cwoe_3550	2.274e-239	746.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CPQW@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
MMS3_k127_709746_26	1380390.JIAT01000010_gene4493	3.359e-05	51.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2GN0H@201174|Actinobacteria,4CQKX@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
MMS3_k127_709746_1	469383.Cwoe_3559	3.561e-240	753.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CP5R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMS3_k127_709746_12	1449069.JMLO01000002_gene4663	1.429e-134	438.0	COG0604@1|root,COG0604@2|Bacteria,2GK40@201174|Actinobacteria,4FVXZ@85025|Nocardiaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	fadB5	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
MMS3_k127_709746_3	469383.Cwoe_3561	1.588e-222	704.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CP5W@84995|Rubrobacteria	84995|Rubrobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
MMS3_k127_709746_6	211114.JOEF01000001_gene7656	6.428e-176	560.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4DY92@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
MMS3_k127_709746_9	1380390.JIAT01000010_gene4476	2.395e-171	544.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CPA6@84995|Rubrobacteria	84995|Rubrobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
MMS3_k127_709746_21	1380390.JIAT01000010_gene4474	1.465e-60	220.0	COG0500@1|root,COG2226@2|Bacteria,2HF4V@201174|Actinobacteria,4CQ4S@84995|Rubrobacteria	84995|Rubrobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Ubie_methyltran
MMS3_k127_709746_13	1380390.JIAT01000010_gene4472	2.788e-134	458.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4CPCU@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_709746_15	929712.KI912613_gene3973	1.051e-129	440.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4CPAK@84995|Rubrobacteria	84995|Rubrobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_709746_14	469383.Cwoe_3570	4.263e-130	425.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CQ7T@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
MMS3_k127_709746_16	1283299.AUKG01000002_gene4858	2.169e-99	336.0	COG4948@1|root,COG4948@2|Bacteria,2HG8P@201174|Actinobacteria,4CPM2@84995|Rubrobacteria	84995|Rubrobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_709746_19	1304872.JAGC01000003_gene3097	8.325e-90	327.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
MMS3_k127_709746_22	1380390.JIAT01000010_gene4466	1.227e-53	215.0	COG2267@1|root,COG2267@2|Bacteria,2GYP0@201174|Actinobacteria,4CQF4@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
MMS3_k127_709746_7	1283299.AUKG01000002_gene4855	6.461e-175	571.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4CPYA@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
MMS3_k127_709746_5	469383.Cwoe_3578	4.21e-188	601.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4CQEB@84995|Rubrobacteria	84995|Rubrobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
MMS3_k127_709746_17	1283299.AUKG01000002_gene4848	7.847e-95	313.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4CR86@84995|Rubrobacteria	84995|Rubrobacteria	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
MMS3_k127_709746_0	469383.Cwoe_3580	1.058e-309	954.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CPN4@84995|Rubrobacteria	84995|Rubrobacteria	E	Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_709746_23	1283299.AUKG01000002_gene4846	2.566e-31	125.0	2BNFC@1|root,32H35@2|Bacteria,2HRCR@201174|Actinobacteria,4CTAA@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_709746_18	1380390.JIAT01000010_gene4454	1.57e-92	310.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CP9F@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
MMS3_k127_748128_1	1380390.JIAT01000010_gene4448	2.252e-192	612.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CPKC@84995|Rubrobacteria	84995|Rubrobacteria	L	COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
MMS3_k127_748128_3	929712.KI912613_gene3992	9.722e-108	380.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4CPTY@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMS3_k127_748128_6	1380390.JIAT01000009_gene2011	0.0002134	53.0	2AWG8@1|root,31NCH@2|Bacteria,2HQYR@201174|Actinobacteria,4CSRI@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_748128_4	469383.Cwoe_3586	3.208e-28	126.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4CQK8@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
MMS3_k127_748128_0	469383.Cwoe_3585	5.695e-217	688.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CPBB@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_748128_2	1380390.JIAT01000010_gene4454	1.303e-173	559.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CP9F@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
MMS3_k127_748128_5	435908.IDSA_03280	1.858e-20	96.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,2QEXC@267893|Idiomarinaceae	1236|Gammaproteobacteria	E	cystathionine gamma-synthase	-	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
MMS3_k127_854531_1	1283299.AUKG01000002_gene4694	8.166e-135	433.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4CPH5@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	DHBP_synthase,GTP_cyclohydro2
MMS3_k127_854531_6	1380390.JIAT01000010_gene4212	3.51e-54	200.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4CQNG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
MMS3_k127_854531_8	469383.Cwoe_3704	1.292e-22	98.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4CQUE@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
MMS3_k127_854531_0	1380390.JIAT01000010_gene4222	4.809e-220	696.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CPUZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
MMS3_k127_854531_3	929712.KI912613_gene739	4.532e-111	367.0	COG1127@1|root,COG1127@2|Bacteria,2GJ1T@201174|Actinobacteria	201174|Actinobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
MMS3_k127_854531_2	118166.JH976537_gene2797	1.219e-134	435.0	COG0667@1|root,COG0667@2|Bacteria,1G11W@1117|Cyanobacteria,1HEZH@1150|Oscillatoriales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_854531_7	469383.Cwoe_3159	3.852e-46	189.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,4CSHW@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
MMS3_k127_854531_5	1206744.BAGL01000027_gene7509	3.523e-71	246.0	COG0491@1|root,COG0491@2|Bacteria,2HGYH@201174|Actinobacteria,4G50S@85025|Nocardiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_854531_4	1380390.JIAT01000001_gene5046	2.9e-72	249.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4CRKQ@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_866992_3	446471.Xcel_1644	7.892e-94	319.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4F4A1@85017|Promicromonosporaceae	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
MMS3_k127_866992_4	1380390.JIAT01000016_gene5542	4.547e-61	215.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4CSPV@84995|Rubrobacteria	84995|Rubrobacteria	H	Aspartate decarboxylase	-	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
MMS3_k127_866992_1	1380390.JIAT01000016_gene5543	1.987e-120	397.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4CQ9E@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
MMS3_k127_866992_2	469383.Cwoe_2883	1.074e-96	327.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CS0J@84995|Rubrobacteria	84995|Rubrobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
MMS3_k127_866992_0	1380390.JIAT01000016_gene5567	0.0	1533.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CPHN@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMS3_k127_866992_9	266117.Rxyl_1600	5.527e-05	51.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
MMS3_k127_866992_8	1056816.JAFQ01000004_gene6333	3.55e-05	51.0	2DBSW@1|root,2ZAU8@2|Bacteria,2GVNT@201174|Actinobacteria	201174|Actinobacteria	S	CRISPR-associated protein, GSU0054 family (Cas_GSU0054)	-	-	-	ko:K19132	-	-	-	-	ko00000,ko02048	-	-	-	-
MMS3_k127_866992_7	1032480.MLP_33830	3.026e-09	61.0	2DREV@1|root,33BF4@2|Bacteria,2ISW7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_866992_6	656024.FsymDg_3168	2.656e-26	112.0	COG1848@1|root,COG1848@2|Bacteria,2GUQC@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_866992_5	1121877.JQKF01000066_gene883	5.596e-53	201.0	COG3064@1|root,COG3064@2|Bacteria,2IPMP@201174|Actinobacteria	201174|Actinobacteria	M	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_88375_8	378806.STAUR_1704	7.214e-114	387.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,437XQ@68525|delta/epsilon subdivisions,2X37P@28221|Deltaproteobacteria,2YUR1@29|Myxococcales	28221|Deltaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_88375_5	469383.Cwoe_1388	1.649e-153	505.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CPFF@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
MMS3_k127_88375_6	469383.Cwoe_4194	9.913e-118	412.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CP5X@84995|Rubrobacteria	84995|Rubrobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
MMS3_k127_88375_2	469383.Cwoe_4193	0.0	1023.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4CPAH@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
MMS3_k127_88375_17	469383.Cwoe_4191	3.861e-33	132.0	COG2127@1|root,COG2127@2|Bacteria,2HPG0@201174|Actinobacteria,4CQUJ@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent Clp protease adaptor protein ClpS	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
MMS3_k127_88375_18	1380390.JIAT01000010_gene3594	5.777e-26	121.0	2AWN7@1|root,31NIY@2|Bacteria,2HR42@201174|Actinobacteria,4CSZD@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_88375_3	1380390.JIAT01000010_gene3595	1.169e-231	732.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4CRE2@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_88375_4	1380390.JIAT01000010_gene3597	3.264e-199	644.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRH0@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_88375_7	469383.Cwoe_4173	4.44e-114	377.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
MMS3_k127_88375_14	1380390.JIAT01000010_gene3606	1.795e-53	192.0	2B8EI@1|root,321PH@2|Bacteria,2HP5J@201174|Actinobacteria,4CQHJ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_88375_19	469383.Cwoe_4169	6.816e-18	88.0	2B8XJ@1|root,32280@2|Bacteria,2HRTD@201174|Actinobacteria,4CTWV@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_88375_15	469383.Cwoe_1226	3.85e-53	199.0	COG0406@1|root,COG0406@2|Bacteria,2HGEQ@201174|Actinobacteria,4CSEQ@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
MMS3_k127_88375_1	1896.JOAU01000012_gene586	0.0	1217.0	COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria	201174|Actinobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
MMS3_k127_88375_0	469383.Cwoe_4165	0.0	1233.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4CPHP@84995|Rubrobacteria	84995|Rubrobacteria	H	Elongator protein 3 MiaB NifB	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
MMS3_k127_88375_10	469383.Cwoe_5680	1.567e-96	340.0	COG2267@1|root,COG2267@2|Bacteria,2GW5Y@201174|Actinobacteria	201174|Actinobacteria	I	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_88375_12	469383.Cwoe_4151	2.497e-86	297.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4CQ5F@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
MMS3_k127_88375_16	1283299.AUKG01000002_gene4396	2.631e-51	190.0	COG1920@1|root,COG1920@2|Bacteria,2HNVD@201174|Actinobacteria,4CQ43@84995|Rubrobacteria	84995|Rubrobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
MMS3_k127_88375_11	1380390.JIAT01000010_gene3613	3.44e-91	321.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4CPHB@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
MMS3_k127_88375_13	1122939.ATUD01000012_gene3154	3.573e-69	253.0	COG2085@1|root,COG2085@2|Bacteria,2ICZ0@201174|Actinobacteria	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
MMS3_k127_88375_9	469383.Cwoe_4125	2.44e-100	351.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4CSSI@84995|Rubrobacteria	84995|Rubrobacteria	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
MMS3_k127_889369_32	1120917.AQXM01000036_gene1218	1.642e-08	58.0	2BZ0J@1|root,2ZDC3@2|Bacteria,2GUSB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_889369_26	1246445.ANAY01000015_gene2466	2.114e-58	226.0	COG3662@1|root,COG3662@2|Bacteria,2GK0G@201174|Actinobacteria,4EFU0@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
MMS3_k127_889369_11	882083.SacmaDRAFT_5654	3.531e-137	440.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria,4E5P5@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_889369_15	265729.GS18_0217485	2.21e-114	388.0	COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,1ZCDM@1386|Bacillus	91061|Bacilli	M	Chitin synthase	icaA	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
MMS3_k127_889369_19	525909.Afer_1523	6.937e-81	280.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria,4CNNI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_889369_18	1449347.JQLN01000007_gene1837	1.102e-85	305.0	COG1290@1|root,COG1290@2|Bacteria,2GK58@201174|Actinobacteria	201174|Actinobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_N_2
MMS3_k127_889369_25	469383.Cwoe_3445	1.232e-58	228.0	COG1503@1|root,COG1503@2|Bacteria,2I8DT@201174|Actinobacteria	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_889369_30	1206741.BAFX01000129_gene2000	4.484e-23	112.0	2APE6@1|root,31EGT@2|Bacteria,2HHZ9@201174|Actinobacteria,4G1UY@85025|Nocardiaceae	201174|Actinobacteria	S	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_889369_13	1283299.AUKG01000006_gene752	3.146e-118	395.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4CR8E@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_889369_2	469383.Cwoe_5435	2.291e-241	764.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_889369_24	518766.Rmar_0654	1.12e-62	224.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
MMS3_k127_889369_5	1122939.ATUD01000025_gene2546	2.15e-190	624.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CP7K@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
MMS3_k127_889369_27	298653.Franean1_3765	2.44e-41	158.0	COG5502@1|root,COG5502@2|Bacteria,2ISMP@201174|Actinobacteria	201174|Actinobacteria	S	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
MMS3_k127_889369_9	1089544.KB912942_gene1881	4.173e-156	536.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4DXVG@85010|Pseudonocardiales	201174|Actinobacteria	G	hydrolase, family 65, central catalytic	kojP	-	2.4.1.230	ko:K10231	-	-	-	-	ko00000,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
MMS3_k127_889369_7	1120973.AQXL01000111_gene924	1.794e-169	559.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,4HDVV@91061|Bacilli,2799W@186823|Alicyclobacillaceae	91061|Bacilli	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
MMS3_k127_889369_31	1380356.JNIK01000004_gene134	1.549e-17	97.0	2E9QE@1|root,333WR@2|Bacteria,2I2DC@201174|Actinobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_889369_28	469383.Cwoe_3192	7.351e-34	135.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CQC7@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS3_k127_889369_4	1380390.JIAT01000010_gene4880	1.514e-202	638.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria,4CPCC@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_889369_34	1123052.AUDF01000004_gene1867	5.401e-05	46.0	COG1716@1|root,COG1716@2|Bacteria,2IRDH@201174|Actinobacteria,4FPYD@85023|Microbacteriaceae	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMS3_k127_889369_14	469383.Cwoe_3189	5.698e-115	380.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CR9C@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
MMS3_k127_889369_0	1380390.JIAT01000010_gene4887	0.0	1182.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CPMB@84995|Rubrobacteria	84995|Rubrobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
MMS3_k127_889369_6	469383.Cwoe_3186	1.574e-187	602.0	COG0608@1|root,COG0608@2|Bacteria,2IK2U@201174|Actinobacteria,4CPI9@84995|Rubrobacteria	84995|Rubrobacteria	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
MMS3_k127_889369_29	1283299.AUKG01000002_gene5234	7.631e-29	118.0	2AUQD@1|root,31KDC@2|Bacteria,2HP8X@201174|Actinobacteria,4CQM7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_889369_1	469383.Cwoe_3183	1.937e-300	952.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CPTZ@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMS3_k127_889369_21	1283299.AUKG01000002_gene5236	7.61e-67	233.0	COG3829@1|root,COG3829@2|Bacteria,2HQG0@201174|Actinobacteria,4CS14@84995|Rubrobacteria	84995|Rubrobacteria	KT	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_889369_8	469383.Cwoe_3181	4.346e-159	511.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CP8G@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
MMS3_k127_889369_23	1380390.JIAT01000010_gene4896	3.97e-64	226.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CQA9@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
MMS3_k127_889369_22	469383.Cwoe_3179	1.717e-64	224.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CQCR@84995|Rubrobacteria	84995|Rubrobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
MMS3_k127_889369_16	469383.Cwoe_3175	4.752e-103	342.0	COG1208@1|root,COG1208@2|Bacteria,2GKHA@201174|Actinobacteria,4CQZH@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
MMS3_k127_889369_17	469383.Cwoe_3178	4.834e-97	339.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CPAM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMS3_k127_889369_3	469383.Cwoe_3174	9.594e-212	668.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CPEU@84995|Rubrobacteria	84995|Rubrobacteria	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_889369_12	469383.Cwoe_3173	7.86e-128	419.0	COG0491@1|root,COG0491@2|Bacteria,2HGYI@201174|Actinobacteria,4CQY2@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_889369_20	469383.Cwoe_3161	9.064e-70	242.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CQEG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
MMS3_k127_889369_10	469383.Cwoe_3160	8.778e-140	452.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CPM6@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
MMS3_k127_940949_7	929712.KI912613_gene1414	3.68e-05	49.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria,4CPMF@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
MMS3_k127_940949_4	1283299.AUKG01000001_gene1958	8.675e-99	332.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4CPPM@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
MMS3_k127_940949_2	211114.JOEF01000002_gene4590	4.573e-106	360.0	COG3177@1|root,COG3177@2|Bacteria,2GN3K@201174|Actinobacteria,4E3SI@85010|Pseudonocardiales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
MMS3_k127_940949_6	1283299.AUKG01000001_gene1956	1.507e-52	187.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4CQED@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
MMS3_k127_940949_0	1380390.JIAT01000009_gene1982	0.0	1279.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CP6P@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
MMS3_k127_940949_5	469383.Cwoe_5847	4.594e-91	310.0	COG0789@1|root,COG0789@2|Bacteria,2HSQA@201174|Actinobacteria,4CS71@84995|Rubrobacteria	84995|Rubrobacteria	K	MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
MMS3_k127_940949_3	1283299.AUKG01000001_gene1943	3.833e-104	345.0	COG0596@1|root,COG0596@2|Bacteria,2HPNV@201174|Actinobacteria,4CR1C@84995|Rubrobacteria	84995|Rubrobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_940949_1	1283299.AUKG01000001_gene1941	2.948e-214	672.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4CPK3@84995|Rubrobacteria	84995|Rubrobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
MMS3_k127_999648_11	479432.Sros_1542	2.988e-13	75.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4EM93@85012|Streptosporangiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
MMS3_k127_999648_7	469383.Cwoe_0010	1.033e-62	229.0	2AVPF@1|root,31MGI@2|Bacteria,2HE2U@201174|Actinobacteria,4CQ1U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_999648_8	469383.Cwoe_0009	6.81e-46	172.0	COG1196@1|root,COG1196@2|Bacteria,2IMXX@201174|Actinobacteria,4CS7C@84995|Rubrobacteria	84995|Rubrobacteria	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
MMS3_k127_999648_5	469383.Cwoe_0008	4.134e-82	284.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CQFQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydratase	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
MMS3_k127_999648_6	1380390.JIAT01000009_gene1786	2.315e-79	270.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CQBX@84995|Rubrobacteria	84995|Rubrobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
MMS3_k127_999648_0	929712.KI912613_gene1126	0.0	1283.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CP85@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMS3_k127_999648_1	1283299.AUKG01000001_gene1758	0.0	1162.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CP8I@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMS3_k127_999648_10	1283299.AUKG01000001_gene1759	1.682e-16	89.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
MMS3_k127_999648_4	1380390.JIAT01000009_gene1789	1.134e-138	449.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CQ4U@84995|Rubrobacteria	84995|Rubrobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
MMS3_k127_999648_3	469383.Cwoe_0002	8.524e-139	450.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CP8Y@84995|Rubrobacteria	84995|Rubrobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
MMS3_k127_999648_2	469383.Cwoe_0001	3.78e-144	473.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CPFC@84995|Rubrobacteria	84995|Rubrobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
MMS3_k127_999648_9	627192.SLG_06430	1.714e-38	151.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,2K3A6@204457|Sphingomonadales	204457|Sphingomonadales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
## 1988 queries scanned
## Total time (seconds): 146.10772800445557
## Rate: 13.61 q/s