## Fri Nov 15 23:43:33 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin17/MMS_3_bin.73.fa -m mmseqs --itype genome -o MMS_3_bin.73 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/MMS_3_bin.73 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
MMS3_k127_1052539_6	1229780.BN381_80226	2.459e-74	258.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,3UWVT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
MMS3_k127_1052539_14	525909.Afer_0756	9.583e-25	112.0	COG0671@1|root,COG0671@2|Bacteria,2HGAE@201174|Actinobacteria,4CN9F@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
MMS3_k127_1052539_5	298655.KI912266_gene422	3.958e-85	291.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EU7W@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_1052539_3	219305.MCAG_03760	2.129e-94	323.0	COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,4D90F@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
MMS3_k127_1052539_10	1394178.AWOO02000005_gene3512	2.667e-56	206.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4EIVH@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
MMS3_k127_1052539_4	1313172.YM304_15380	5.234e-87	297.0	COG3394@1|root,COG3394@2|Bacteria,2HG9M@201174|Actinobacteria,4CN7Z@84992|Acidimicrobiia	84992|Acidimicrobiia	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
MMS3_k127_1052539_2	1313172.YM304_15360	8.715e-98	328.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4CN0C@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
MMS3_k127_1052539_7	446468.Ndas_0952	6.385e-72	261.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4EGYB@85012|Streptosporangiales	201174|Actinobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
MMS3_k127_1052539_1	298653.Franean1_2532	3.472e-110	365.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4EUCH@85013|Frankiales	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMS3_k127_1052539_12	1155718.KB891940_gene4719	2.794e-49	186.0	arCOG04740@1|root,31PZA@2|Bacteria,2GP15@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1052539_11	1313172.YM304_37950	1.558e-50	196.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4CNVE@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
MMS3_k127_1052539_0	351607.Acel_1446	1.384e-126	415.0	COG0215@1|root,COG0215@2|Bacteria,2GJ4W@201174|Actinobacteria,4ERBT@85013|Frankiales	201174|Actinobacteria	J	PFAM Cysteinyl-tRNA synthetase class Ia	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
MMS3_k127_1052539_9	1229780.BN381_470022	3.478e-62	224.0	COG0730@1|root,COG0730@2|Bacteria,2HGFU@201174|Actinobacteria,3UXNM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
MMS3_k127_1052539_13	1869.MB27_21030	3.026e-26	113.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS3_k127_1052539_8	1444309.JAQG01000017_gene770	4.816e-69	250.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,26QN7@186822|Paenibacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
MMS3_k127_1067180_4	1894.JOER01000017_gene4779	8.576e-05	51.0	2DP3A@1|root,330CA@2|Bacteria,2GPHQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Gly_rich
MMS3_k127_1067180_1	795666.MW7_3417	1.887e-48	185.0	COG1028@1|root,COG1028@2|Bacteria,1NTI2@1224|Proteobacteria,2VK21@28216|Betaproteobacteria,1K1T1@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	short-chain dehydrogenase	-	-	1.3.1.58	ko:K07535,ko:K10620	ko00362,ko00622,ko01120,ko01220,map00362,map00622,map01120,map01220	M00539,M00540	R05240,R05582	RC00057,RC00154	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
MMS3_k127_1067180_3	47839.CCAU010000009_gene1693	5.765e-09	64.0	COG1878@1|root,COG1878@2|Bacteria,2HNJS@201174|Actinobacteria,23799@1762|Mycobacteriaceae	201174|Actinobacteria	K	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMS3_k127_1067180_2	983545.Glaag_2471	7.886e-30	122.0	COG1917@1|root,COG1917@2|Bacteria,1N26Z@1224|Proteobacteria,1SEKQ@1236|Gammaproteobacteria,46C80@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_1067180_0	1122611.KB903973_gene2560	0.0	1050.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,2GKBW@201174|Actinobacteria,4EMI5@85012|Streptosporangiales	201174|Actinobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00179,ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR,POR_N,TPP_enzyme_C
MMS3_k127_1078477_17	188626.HMPREF0321_0197	7.3e-22	106.0	COG2367@1|root,COG2367@2|Bacteria,2GKPU@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
MMS3_k127_1078477_3	525909.Afer_1061	2.066e-196	625.0	COG0477@1|root,COG2814@2|Bacteria,2I2ZF@201174|Actinobacteria,4CNM3@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1078477_13	1223523.H340_01954	7.283e-51	204.0	COG0454@1|root,COG0456@2|Bacteria,2GJJZ@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
MMS3_k127_1078477_9	1048834.TC41_0139	2.208e-64	238.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,278QY@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
MMS3_k127_1078477_8	28042.GU90_16725	1.389e-64	228.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4E4Q8@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_1078477_4	710687.KI912270_gene4496	5.079e-152	496.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,236XH@1762|Mycobacteriaceae	201174|Actinobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
MMS3_k127_1078477_2	1108045.GORHZ_118_00140	8.033e-212	670.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2I2DV@201174|Actinobacteria	201174|Actinobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4,Fer4_11,Fer4_3,Fer4_4,Fer4_7,NrfD
MMS3_k127_1078477_0	1123023.JIAI01000001_gene7200	0.0	1623.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
MMS3_k127_1078477_14	68170.KL590535_gene3736	3.846e-42	161.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,4E4ZR@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
MMS3_k127_1078477_15	1035308.AQYY01000001_gene3227	1.504e-28	117.0	COG1937@1|root,COG1937@2|Bacteria	2|Bacteria	S	negative regulation of transcription, DNA-templated	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
MMS3_k127_1078477_16	935866.JAER01000012_gene3505	1.686e-25	110.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria,4DV51@85009|Propionibacteriales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS3_k127_1078477_1	235985.BBPN01000004_gene3191	7.869e-228	728.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,2NFQS@228398|Streptacidiphilus	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_1078477_6	1123023.JIAI01000005_gene671	3.921e-69	239.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria,4E47X@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
MMS3_k127_1078477_7	1267535.KB906767_gene3006	7.266e-67	238.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
MMS3_k127_1078477_10	1246995.AFR_04305	7.916e-63	219.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1078477_21	36875.HQ29_03465	1.419e-06	58.0	COG0425@1|root,COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0425@2|Bacteria,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,4PKEU@976|Bacteroidetes,2FKZ0@200643|Bacteroidia,22WZ3@171551|Porphyromonadaceae	976|Bacteroidetes	P	Belongs to the sulfur carrier protein TusA family	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
MMS3_k127_1078477_20	935866.JAER01000056_gene291	2.994e-09	70.0	2DPKM@1|root,332IX@2|Bacteria,2GU8W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1078477_5	1121877.JQKF01000007_gene1029	7.503e-138	456.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_1078477_22	1163408.UU9_14635	6.446e-05	47.0	2EH45@1|root,33AW4@2|Bacteria,1NM3F@1224|Proteobacteria,1SGQD@1236|Gammaproteobacteria,1X8ZN@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1078477_12	1187851.A33M_2608	4.907e-59	215.0	COG2084@1|root,COG2084@2|Bacteria,1R889@1224|Proteobacteria,2TUEY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_1078477_18	1040983.AXAE01000012_gene2013	6.072e-12	68.0	2DRQB@1|root,33CKR@2|Bacteria,1MZI3@1224|Proteobacteria,2UDVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1078477_11	1120950.KB892771_gene1312	5.513e-61	217.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria,4DRJF@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1078477_23	1305732.JAGG01000001_gene1490	0.0007787	50.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4FRZ2@85023|Microbacteriaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
MMS3_k127_1078477_19	1146883.BLASA_1358	1.762e-09	58.0	COG2337@1|root,COG2337@2|Bacteria,2IMGQ@201174|Actinobacteria	201174|Actinobacteria	T	Evidence 2b Function of strongly homologous gene	mazF5	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
MMS3_k127_1134002_3	1313172.YM304_33370	1.929e-78	278.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CNNX@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
MMS3_k127_1134002_2	397278.JOJN01000006_gene1029	1.248e-106	355.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4DPPD@85009|Propionibacteriales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
MMS3_k127_1134002_6	365528.KB891269_gene5983	3.379e-53	196.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4ESNJ@85013|Frankiales	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
MMS3_k127_1134002_1	222534.KB893716_gene1811	1.91e-110	369.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4EU10@85013|Frankiales	201174|Actinobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMS3_k127_1134002_4	710685.MycrhN_2355	2.305e-77	262.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,234GK@1762|Mycobacteriaceae	201174|Actinobacteria	C	2Fe-2S -binding domain	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_1134002_0	1380356.JNIK01000014_gene3405	0.0	1043.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4ETP4@85013|Frankiales	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3,1.5.99.4	ko:K03520,ko:K19820	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_1134002_5	1028801.RG1141_CH13250	2.169e-75	264.0	COG0500@1|root,COG2226@2|Bacteria,1REVA@1224|Proteobacteria,2U929@28211|Alphaproteobacteria,4BC95@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS3_k127_1134002_7	1137268.AZXF01000005_gene3291	8.72e-33	130.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4EJH6@85012|Streptosporangiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
MMS3_k127_1134002_8	1121933.AUHH01000051_gene296	5.096e-23	112.0	COG5479@1|root,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4DVI3@85009|Propionibacteriales	201174|Actinobacteria	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
MMS3_k127_1154069_12	471852.Tcur_2494	1.467e-74	262.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EFMP@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
MMS3_k127_1154069_10	1229780.BN381_350134	1.564e-86	317.0	COG0412@1|root,COG0412@2|Bacteria,2GK7H@201174|Actinobacteria	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
MMS3_k127_1154069_11	298655.KI912266_gene3402	3.006e-77	280.0	COG0183@1|root,COG0183@2|Bacteria,2I3PP@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
MMS3_k127_1154069_6	1463920.JOGB01000003_gene2631	1.54e-112	394.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
MMS3_k127_1154069_8	67352.JODS01000038_gene6671	1.514e-93	330.0	COG4987@1|root,COG4987@2|Bacteria,2H79B@201174|Actinobacteria	201174|Actinobacteria	CO	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	cydC	-	-	ko:K06148,ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
MMS3_k127_1154069_7	235985.BBPN01000002_gene5137	4.163e-109	373.0	COG4677@1|root,COG4677@2|Bacteria,2I5JZ@201174|Actinobacteria,2NKFF@228398|Streptacidiphilus	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
MMS3_k127_1154069_16	1463861.JNXE01000001_gene5183	2.35e-46	176.0	2BZNP@1|root,30717@2|Bacteria,2IAEK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
MMS3_k127_1154069_20	1123024.AUII01000028_gene2518	1.445e-39	160.0	COG0406@1|root,COG0406@2|Bacteria,2HRP2@201174|Actinobacteria,4EAZ6@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
MMS3_k127_1154069_26	1095767.CAHD01000193_gene176	4.687e-24	117.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,4F15G@85016|Cellulomonadaceae	201174|Actinobacteria	S	C4-type zinc ribbon domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
MMS3_k127_1154069_19	1313172.YM304_29420	5.165e-41	168.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_1154069_13	1140.Synpcc7942_1598	1.165e-62	224.0	COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1H0JF@1129|Synechococcus	1117|Cyanobacteria	S	Phenazine biosynthesis protein, PhzF family	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
MMS3_k127_1154069_3	253839.SSNG_03336	1.261e-148	480.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	dapC	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_1154069_22	1157632.AQWQ01000003_gene2083	1.144e-32	145.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
MMS3_k127_1154069_4	298654.FraEuI1c_4031	6.476e-141	466.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4ERV6@85013|Frankiales	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
MMS3_k127_1154069_1	471852.Tcur_2562	4.072e-225	705.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4EGGS@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.11,4.1.1.25,4.1.2.27	ko:K01634,ko:K18933	ko00350,ko00410,ko00600,ko00680,ko00770,ko01100,ko01110,ko04071,map00350,map00410,map00600,map00680,map00770,map01100,map01110,map04071	M00100	R00489,R00736,R02464,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
MMS3_k127_1154069_23	1283283.ATXA01000019_gene2901	3.851e-30	132.0	COG4447@1|root,COG5184@1|root,COG4447@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin-like,DUF3494
MMS3_k127_1154069_17	208444.JNYY01000013_gene7634	1.052e-45	169.0	COG1522@1|root,COG1522@2|Bacteria,2GN6I@201174|Actinobacteria,4E3UQ@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
MMS3_k127_1154069_14	1370125.AUWT01000020_gene4674	2.795e-56	209.0	COG0500@1|root,COG2226@2|Bacteria,2I3AK@201174|Actinobacteria,23FDM@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_1154069_25	1192034.CAP_1569	8.261e-26	119.0	COG3332@1|root,COG3332@2|Bacteria,1PUN1@1224|Proteobacteria,434TB@68525|delta/epsilon subdivisions,2WZ4B@28221|Deltaproteobacteria,2Z1AV@29|Myxococcales	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
MMS3_k127_1154069_0	1121877.JQKF01000012_gene332	1.018e-289	908.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4CNI9@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
MMS3_k127_1154069_18	525909.Afer_1887	8.95e-45	189.0	COG2385@1|root,COG2385@2|Bacteria,2HGNA@201174|Actinobacteria,4CNPA@84992|Acidimicrobiia	84992|Acidimicrobiia	D	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1154069_15	351607.Acel_1461	5.734e-52	213.0	COG2247@1|root,COG4934@1|root,COG2247@2|Bacteria,COG4934@2|Bacteria,2HEYG@201174|Actinobacteria,4EVX7@85013|Frankiales	2|Bacteria	M	Pro-kumamolisin, activation domain	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	CW_binding_2,Peptidase_S8,Pro-kuma_activ,fn3
MMS3_k127_1154069_9	314278.NB231_00235	1.18e-86	300.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X0BB@135613|Chromatiales	135613|Chromatiales	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
MMS3_k127_1154069_2	118163.Ple7327_2930	6.802e-178	568.0	COG4992@1|root,COG4992@2|Bacteria,1G4MC@1117|Cyanobacteria,3VMJX@52604|Pleurocapsales	1117|Cyanobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_1154069_5	330084.JNYZ01000010_gene6836	2.256e-120	404.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4EARD@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,Sulfatase
MMS3_k127_1154069_21	710687.KI912270_gene1376	1.251e-38	147.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,236W3@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_116901_13	134676.ACPL_2705	0.0003834	51.0	2B34J@1|root,31VS9@2|Bacteria,2GW54@201174|Actinobacteria,4DFUC@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3558
MMS3_k127_116901_1	216594.MMAR_0286	1.264e-106	361.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
MMS3_k127_116901_10	675635.Psed_2836	1.762e-46	178.0	COG0500@1|root,COG2226@2|Bacteria,2HQHQ@201174|Actinobacteria,4E79H@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_116901_9	1108045.GORHZ_055_00200	1.608e-49	187.0	COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_116901_2	247634.GPB2148_3615	2.57e-96	329.0	COG5285@1|root,COG5285@2|Bacteria,1NXM8@1224|Proteobacteria	1224|Proteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
MMS3_k127_116901_8	1169161.KB897726_gene1403	4.214e-52	196.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria	201174|Actinobacteria	KT	Phage shock protein A	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
MMS3_k127_116901_4	710685.MycrhN_4981	2.982e-93	317.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,235K9@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha/beta hydrolase family	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_116901_7	797209.ZOD2009_17013	2.142e-57	213.0	COG0665@1|root,arCOG00755@2157|Archaea,2XSYW@28890|Euryarchaeota,23SB4@183963|Halobacteria	183963|Halobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_116901_5	1283299.AUKG01000002_gene4368	3.09e-69	247.0	COG0598@1|root,COG0598@2|Bacteria,2HPVI@201174|Actinobacteria,4CRZ0@84995|Rubrobacteria	84995|Rubrobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
MMS3_k127_116901_11	1171373.PACID_26630	1.686e-34	149.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMS3_k127_116901_12	1463845.JOIG01000007_gene764	4.639e-11	70.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154,ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS3_k127_116901_3	1169154.KB897783_gene4571	1.722e-93	319.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria	201174|Actinobacteria	E	Glycine oxidase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_116901_0	298655.KI912267_gene7175	0.0	2130.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4ERS2@85013|Frankiales	201174|Actinobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
MMS3_k127_116901_6	710111.FraQA3DRAFT_6543	9.365e-62	214.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4ERK8@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
MMS3_k127_1191245_2	1122182.KB903825_gene680	3.508e-14	81.0	COG3942@1|root,COG5640@1|root,COG3942@2|Bacteria,COG5640@2|Bacteria,2I1PM@201174|Actinobacteria,4DKSI@85008|Micromonosporales	201174|Actinobacteria	O	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
MMS3_k127_1191245_0	196162.Noca_3634	1.329e-182	584.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DPV7@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
MMS3_k127_1191245_4	1247726.MIM_c38370	3.732e-09	62.0	COG1853@1|root,COG1853@2|Bacteria,1MXQV@1224|Proteobacteria,2WA4R@28216|Betaproteobacteria,3T4UY@506|Alcaligenaceae	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
MMS3_k127_1191245_1	298654.FraEuI1c_3723	5.642e-97	330.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_1297916_4	1463856.JOHY01000041_gene7204	3.746e-78	281.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
MMS3_k127_1297916_3	219305.MCAG_00324	6.46e-79	273.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DA38@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1297916_6	298654.FraEuI1c_3420	1.311e-38	166.0	COG0683@1|root,COG0683@2|Bacteria,2HZXR@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMS3_k127_1297916_2	1282876.BAOK01000001_gene2473	9.527e-135	466.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2UAFI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
MMS3_k127_1297916_0	525909.Afer_1092	3.93e-191	612.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMUC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
MMS3_k127_1297916_8	298654.FraEuI1c_3270	1.245e-17	85.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	MA20_25230	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
MMS3_k127_1297916_1	1229780.BN381_640016	6.236e-169	542.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	bglIM	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
MMS3_k127_1297916_9	326298.Suden_0122	6.471e-07	61.0	2BUAB@1|root,32PJW@2|Bacteria,1Q49J@1224|Proteobacteria,42YP0@68525|delta/epsilon subdivisions,2YR52@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1297916_5	67281.JNZZ01000006_gene5465	1.404e-44	173.0	COG1670@1|root,COG1670@2|Bacteria,2HYD5@201174|Actinobacteria,41C6S@629295|Streptomyces griseus group	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_1297916_7	436229.JOEH01000021_gene7742	1.124e-22	105.0	COG1024@1|root,COG1024@2|Bacteria,2GN69@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_138481_3	561175.KB894103_gene1258	9.737e-94	313.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4EH1N@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
MMS3_k127_138481_0	1121877.JQKF01000003_gene1565	1.09e-223	699.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CMS9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_138481_1	405948.SACE_5690	1.898e-173	552.0	COG0451@1|root,COG0451@2|Bacteria,2GJJG@201174|Actinobacteria,4DYHF@85010|Pseudonocardiales	201174|Actinobacteria	GM	PFAM NAD dependent epimerase dehydratase family	sqdB	-	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	-	Epimerase
MMS3_k127_138481_2	469383.Cwoe_3374	2.882e-125	415.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
MMS3_k127_1417937_23	1123269.NX02_14775	0.0003855	43.0	COG1960@1|root,COG1960@2|Bacteria,1P4V3@1224|Proteobacteria,2U8Q3@28211|Alphaproteobacteria,2K277@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
MMS3_k127_1417937_2	1157635.KB892013_gene2483	9.388e-175	567.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria	201174|Actinobacteria	K	helix-turn-helix- domain containing protein, AraC type	alkA	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
MMS3_k127_1417937_19	1048339.KB913029_gene2186	1.848e-43	169.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4ET2S@85013|Frankiales	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
MMS3_k127_1417937_13	298655.KI912266_gene3026	4.658e-79	272.0	COG1028@1|root,COG1028@2|Bacteria,2GP5U@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_1417937_12	653045.Strvi_5042	3.455e-85	289.0	COG0412@1|root,COG0412@2|Bacteria,2HVNP@201174|Actinobacteria	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
MMS3_k127_1417937_1	47763.JNZA01000027_gene5868	9.423e-189	596.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_1417937_5	1123320.KB889585_gene1872	3.643e-165	527.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1417937_14	1160718.SU9_17060	4.904e-73	264.0	COG1960@1|root,COG1960@2|Bacteria,2GK9C@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE27	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
MMS3_k127_1417937_10	68570.DC74_3712	5.871e-106	370.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_1417937_22	1151061.CAJY01000028_gene1184	6.251e-06	56.0	2DSZE@1|root,33I16@2|Bacteria,2IMV6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1453
MMS3_k127_1417937_15	28042.GU90_07615	5.103e-73	252.0	COG0406@1|root,COG0406@2|Bacteria,2HUBQ@201174|Actinobacteria,4E141@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
MMS3_k127_1417937_18	285535.JOEY01000015_gene4230	2.025e-44	170.0	COG3591@1|root,COG3591@2|Bacteria,2I9M2@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1417937_6	266940.Krad_1135	9.435e-161	528.0	COG0465@1|root,COG0465@2|Bacteria,2I9X7@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the AAA ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
MMS3_k127_1417937_20	68194.JNXR01000018_gene293	3.184e-39	158.0	COG1545@1|root,COG1545@2|Bacteria,2IHZR@201174|Actinobacteria	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_1417937_3	1229780.BN381_130126	2.763e-168	542.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	aldA_1	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_1417937_7	1297742.A176_02025	1.056e-121	403.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NCK@68525|delta/epsilon subdivisions,2WMCF@28221|Deltaproteobacteria,2YTU4@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
MMS3_k127_1417937_16	1157638.KB892174_gene323	7.222e-72	261.0	COG1028@1|root,COG1028@2|Bacteria,2ICJK@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1417937_17	397278.JOJN01000002_gene748	7.348e-56	208.0	COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria,4DQ73@85009|Propionibacteriales	201174|Actinobacteria	S	Creatinine amidohydrolase	mftE	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_1417937_4	1157638.KB892174_gene330	8.459e-168	535.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	pqqE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
MMS3_k127_1417937_21	1906.SFRA_12465	2.733e-20	94.0	COG0535@1|root,COG0535@2|Bacteria,2GQQT@201174|Actinobacteria	201174|Actinobacteria	S	Mycofactocin system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1417937_11	1394178.AWOO02000085_gene993	4.92e-98	342.0	COG1216@1|root,COG1216@2|Bacteria,2I176@201174|Actinobacteria,4EM9E@85012|Streptosporangiales	201174|Actinobacteria	S	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1417937_0	101510.RHA1_ro06073	3.546e-195	618.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4FU09@85025|Nocardiaceae	201174|Actinobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
MMS3_k127_1417937_8	1394178.AWOO02000017_gene6792	1.463e-120	398.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4EN8T@85012|Streptosporangiales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1417937_9	298655.KI912266_gene5570	4.948e-106	364.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria,4EVXM@85013|Frankiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMS3_k127_1430583_17	1282876.BAOK01000001_gene3486	3.199e-10	74.0	COG1960@1|root,COG1960@2|Bacteria,1R7M8@1224|Proteobacteria,2TS45@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
MMS3_k127_1430583_7	13690.CP98_00468	2.212e-107	361.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria,2K1N3@204457|Sphingomonadales	204457|Sphingomonadales	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1430583_12	1179778.PMM47T1_15531	1.698e-61	222.0	COG1024@1|root,COG1024@2|Bacteria,1R3U7@1224|Proteobacteria,1RRUT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_1430583_8	479434.Sthe_0006	2.297e-103	358.0	COG1804@1|root,COG1804@2|Bacteria,2GBSM@200795|Chloroflexi,27Z2E@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	2.8.3.20	ko:K18313	-	-	R10640,R10641	RC00014	ko00000,ko01000	-	-	-	CoA_transf_3
MMS3_k127_1430583_10	1246995.AFR_04305	4.457e-84	297.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1430583_5	1123320.KB889585_gene1916	5.236e-125	424.0	COG0318@1|root,COG0318@2|Bacteria,2I91U@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_1430583_6	487521.OCU_07630	5.12e-115	383.0	COG1960@1|root,COG1960@2|Bacteria,2GK9U@201174|Actinobacteria,233DU@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1430583_20	868131.MSWAN_2292	8.095e-06	54.0	COG0599@1|root,arCOG02151@2157|Archaea,2Y0SW@28890|Euryarchaeota	28890|Euryarchaeota	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_1430583_0	1123320.KB889689_gene527	1.468e-202	655.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1430583_2	479433.Caci_8761	2.06e-163	524.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	ltp2	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
MMS3_k127_1430583_4	557599.MKAN_07645	2.61e-131	431.0	COG2124@1|root,COG2124@2|Bacteria,2GKKN@201174|Actinobacteria,23477@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.15.13	ko:K17474	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
MMS3_k127_1430583_19	311424.DhcVS_1218	2.474e-07	61.0	COG1309@1|root,COG1309@2|Bacteria,2G72N@200795|Chloroflexi,34DFE@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1430583_16	232348.ADXL01000039_gene1713	2.829e-12	75.0	COG0664@1|root,COG3176@1|root,COG0664@2|Bacteria,COG3176@2|Bacteria,1GP4W@1117|Cyanobacteria,1H29Q@1129|Synechococcus	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,cNMP_binding
MMS3_k127_1430583_1	298654.FraEuI1c_4128	5.718e-176	569.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria,4ESDV@85013|Frankiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_1430583_11	298655.KI912266_gene2716	2.602e-67	244.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EU2D@85013|Frankiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1430583_9	1123320.KB889585_gene1897	2.171e-85	299.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1430583_3	2002.JOEQ01000012_gene5842	7.559e-145	475.0	COG0183@1|root,COG0183@2|Bacteria,2IBBS@201174|Actinobacteria,4EMWB@85012|Streptosporangiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
MMS3_k127_1430583_13	675635.Psed_1909	4.062e-30	130.0	COG4923@1|root,COG4923@2|Bacteria,2IQKY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
MMS3_k127_1430583_14	287986.DV20_34510	1.616e-28	122.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria,4E6B1@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_1481160_4	326424.FRAAL1969	2.386e-69	267.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4ERCB@85013|Frankiales	201174|Actinobacteria	P	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
MMS3_k127_1481160_0	1123322.KB904718_gene5093	2.318e-252	800.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMS3_k127_1481160_1	67281.JNZZ01000042_gene3790	1.676e-113	380.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,419T5@629295|Streptomyces griseus group	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_1481160_2	1283283.ATXA01000001_gene714	1.361e-81	287.0	COG2141@1|root,COG2141@2|Bacteria,2GJ3B@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase, MSMEG_3544 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_1481160_3	1382304.JNIL01000001_gene957	3.578e-80	279.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HAM3@91061|Bacilli	91061|Bacilli	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
MMS3_k127_1481160_5	997346.HMPREF9374_0763	2.325e-13	72.0	COG2050@1|root,COG2050@2|Bacteria,1V7G2@1239|Firmicutes,4HIIA@91061|Bacilli	91061|Bacilli	Q	protein possibly involved in aromatic compounds catabolism	yuxO	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_1498238_4	512565.AMIS_53110	3.177e-54	209.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway VirD4	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C
MMS3_k127_1498238_2	710696.Intca_3110	6.433e-88	309.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4FEPS@85021|Intrasporangiaceae	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1498238_3	298654.FraEuI1c_3281	1.553e-55	207.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1498238_0	298654.FraEuI1c_3280	3.248e-185	585.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
MMS3_k127_1498238_1	1380386.JIAW01000029_gene3651	6.816e-146	468.0	COG1028@1|root,COG1028@2|Bacteria,2ICWR@201174|Actinobacteria,23580@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1498238_5	1348663.KCH_07400	6.401e-22	101.0	COG3619@1|root,COG3619@2|Bacteria,2GKDV@201174|Actinobacteria,2M3GD@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
MMS3_k127_1511991_6	479432.Sros_8985	5.964e-33	129.0	COG0685@1|root,COG0685@2|Bacteria,2IAS3@201174|Actinobacteria,4EM2M@85012|Streptosporangiales	201174|Actinobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
MMS3_k127_1511991_7	882083.SacmaDRAFT_2630	1.112e-30	133.0	COG2021@1|root,COG2021@2|Bacteria,2IMKC@201174|Actinobacteria,4E4FE@85010|Pseudonocardiales	201174|Actinobacteria	E	hydrolase or acyltransferase of alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
MMS3_k127_1511991_8	1120950.KB892762_gene5508	1.176e-25	114.0	COG4274@1|root,COG4274@2|Bacteria,2HWQ8@201174|Actinobacteria,4DW30@85009|Propionibacteriales	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_1511991_1	591158.SSMG_04038	3.561e-88	304.0	COG3391@1|root,COG3391@2|Bacteria,2I8WU@201174|Actinobacteria	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1511991_5	1380370.JIBA01000018_gene472	1.133e-45	170.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4FH0S@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_1511991_2	298655.KI912267_gene6999	5.796e-77	267.0	COG1305@1|root,COG1305@2|Bacteria,2GN5D@201174|Actinobacteria,4ESH4@85013|Frankiales	201174|Actinobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
MMS3_k127_1511991_3	477641.MODMU_0578	4.684e-74	263.0	COG2307@1|root,COG2307@2|Bacteria,2GN0T@201174|Actinobacteria,4ERUV@85013|Frankiales	201174|Actinobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
MMS3_k127_1511991_0	656024.FsymDg_1744	5.857e-196	626.0	COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4ES9X@85013|Frankiales	201174|Actinobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2
MMS3_k127_1511991_4	1242864.D187_005223	8.803e-48	184.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
MMS3_k127_1559781_2	1041522.MCOL_V210040	6.49e-122	400.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,235CZ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
MMS3_k127_1559781_20	1157634.KB912948_gene6301	2.112e-25	119.0	2E339@1|root,32Y3E@2|Bacteria,2IJ6D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1559781_13	765420.OSCT_1998	4.768e-63	241.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_1559781_8	1122939.ATUD01000001_gene59	3.822e-79	271.0	COG1216@1|root,COG1216@2|Bacteria,2HFMY@201174|Actinobacteria,4CSCK@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1559781_12	1121926.AXWO01000008_gene2924	1.146e-64	227.0	COG1216@1|root,COG3222@1|root,COG1216@2|Bacteria,COG3222@2|Bacteria,2I54C@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF2064,Glycos_transf_2
MMS3_k127_1559781_3	1122939.ATUD01000001_gene60	1.489e-116	391.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4CQZB@84995|Rubrobacteria	84995|Rubrobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_1559781_11	1123320.KB889679_gene2455	8.876e-69	242.0	COG0300@1|root,COG0300@2|Bacteria,2GNPI@201174|Actinobacteria	201174|Actinobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	phbB	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
MMS3_k127_1559781_6	525909.Afer_0701	3.981e-91	316.0	29BBV@1|root,2ZYA6@2|Bacteria,2ICWN@201174|Actinobacteria,4CNPC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
MMS3_k127_1559781_21	1449347.JQLN01000001_gene516	6.547e-14	76.0	COG1141@1|root,COG1141@2|Bacteria,2GSJ7@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_15
MMS3_k127_1559781_7	1246995.AFR_33480	6.188e-90	312.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,4DBY4@85008|Micromonosporales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMS3_k127_1559781_17	1463887.KL590036_gene3626	1.777e-49	198.0	COG4097@1|root,COG4097@2|Bacteria,2GQH2@201174|Actinobacteria	201174|Actinobacteria	P	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
MMS3_k127_1559781_9	1172181.KB911708_gene8108	8.447e-78	277.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMS3_k127_1559781_19	1183438.GKIL_1905	7.587e-29	134.0	COG5002@1|root,COG5002@2|Bacteria,1GPX6@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1559781_16	379066.GAU_3138	5.938e-52	191.0	COG0745@1|root,COG0745@2|Bacteria	379066.GAU_3138|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1559781_18	298654.FraEuI1c_2040	8.083e-31	130.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria	201174|Actinobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_1559781_4	926560.KE387023_gene2049	4.414e-109	389.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
MMS3_k127_1559781_22	1283299.AUKG01000002_gene4318	0.000774	51.0	2ABPY@1|root,31162@2|Bacteria,2IJUF@201174|Actinobacteria	201174|Actinobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
MMS3_k127_1559781_5	1343740.M271_01365	4.114e-98	344.0	COG2025@1|root,COG2086@1|root,COG2025@2|Bacteria,COG2086@2|Bacteria,2IIH6@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
MMS3_k127_1559781_1	1211815.CBYP010000048_gene1668	8.667e-149	488.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4EUJP@85013|Frankiales	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	ywrD	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_1559781_0	1123322.KB904735_gene1547	1.103e-185	585.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	adhC	-	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1559781_15	2074.JNYD01000009_gene5334	6.556e-57	203.0	COG0346@1|root,COG0346@2|Bacteria,2IPA6@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_1559781_14	258533.BN977_05278	5.609e-60	218.0	COG4280@1|root,COG4280@2|Bacteria,2GN58@201174|Actinobacteria,236RB@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
MMS3_k127_1559781_10	710686.Mycsm_01689	8.057e-72	263.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria,236MM@1762|Mycobacteriaceae	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_1562174_12	365528.KB891209_gene2170	4.356e-12	68.0	COG1033@1|root,COG1033@2|Bacteria,2I731@201174|Actinobacteria	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_1562174_6	1121877.JQKF01000011_gene366	2.867e-138	456.0	COG1457@1|root,COG1457@2|Bacteria,2GJ6B@201174|Actinobacteria,4CNGD@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
MMS3_k127_1562174_10	298654.FraEuI1c_3779	2.583e-67	236.0	COG0503@1|root,COG0503@2|Bacteria,2H50R@201174|Actinobacteria	201174|Actinobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
MMS3_k127_1562174_2	1214101.BN159_4585	5.47e-180	584.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
MMS3_k127_1562174_3	1394178.AWOO02000011_gene3916	6.577e-162	545.0	COG4987@1|root,COG4987@2|Bacteria,2H79B@201174|Actinobacteria	201174|Actinobacteria	CO	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	cydC	-	-	ko:K16012,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
MMS3_k127_1562174_1	1121946.AUAX01000018_gene6936	2.564e-198	629.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4DA5S@85008|Micromonosporales	201174|Actinobacteria	C	PFAM cytochrome bd ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
MMS3_k127_1562174_9	1121946.AUAX01000018_gene6937	3.821e-107	358.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4DATV@85008|Micromonosporales	201174|Actinobacteria	C	cytochrome d ubiquinol oxidase, subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
MMS3_k127_1562174_7	1454004.AW11_02083	7.65e-115	375.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2WF0A@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
MMS3_k127_1562174_0	1449069.JMLO01000028_gene4486	2.391e-250	787.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4FWEE@85025|Nocardiaceae	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
MMS3_k127_1562174_5	222534.KB893705_gene5846	2.065e-140	461.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4ES4Y@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_1562174_8	1068980.ARVW01000001_gene5613	3.939e-111	364.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	hdhA	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
MMS3_k127_1562174_4	585531.HMPREF0063_12555	7.325e-156	499.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria,4DNMG@85009|Propionibacteriales	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
MMS3_k127_1562174_11	1001240.GY21_09500	1.247e-51	190.0	COG0346@1|root,COG0346@2|Bacteria,2GQZ9@201174|Actinobacteria,4FT4H@85023|Microbacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_1562174_13	1121272.KB903291_gene3503	7.293e-10	61.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4D8EW@85008|Micromonosporales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
MMS3_k127_1633690_2	1121877.JQKF01000001_gene1385	2.483e-97	331.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CMYJ@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMS3_k127_1633690_0	1229780.BN381_80100	3.237e-282	895.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,3UX71@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_1633690_5	1229780.BN381_80101	9.816e-51	194.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria,3UXQA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
MMS3_k127_1633690_1	269800.Tfu_2183	3.621e-133	446.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4EGIT@85012|Streptosporangiales	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
MMS3_k127_1633690_6	1313172.YM304_18460	1.784e-33	131.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4CN9R@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
MMS3_k127_1633690_7	1122602.ATXP01000016_gene1256	2.86e-26	121.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,1W9T0@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
MMS3_k127_1633690_8	405948.SACE_2906	1.431e-19	101.0	COG0346@1|root,COG0346@2|Bacteria,2H1FK@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_1633690_4	1078020.KEK_00960	7.771e-57	218.0	COG0005@1|root,COG0005@2|Bacteria,2GKEI@201174|Actinobacteria,232K8@1762|Mycobacteriaceae	201174|Actinobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_1633690_3	118166.JH976537_gene3035	5.029e-64	234.0	COG3733@1|root,COG3733@2|Bacteria,1G2YB@1117|Cyanobacteria,1HE6W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Copper amine oxidase, enzyme domain	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
MMS3_k127_1688378_2	1463887.KL589987_gene6856	5.204e-168	535.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria	201174|Actinobacteria	I	Squalene--hopene cyclase	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
MMS3_k127_1688378_15	994479.GL877879_gene5895	2.104e-101	341.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4DZDW@85010|Pseudonocardiales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS3_k127_1688378_3	1394178.AWOO02000022_gene7138	1.075e-167	531.0	COG0535@1|root,COG0535@2|Bacteria,2I0Y0@201174|Actinobacteria,4EGYF@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_14,Radical_SAM
MMS3_k127_1688378_29	1380347.JNII01000006_gene1785	9.791e-41	161.0	COG0726@1|root,COG0726@2|Bacteria,2GMC2@201174|Actinobacteria,4EVH6@85013|Frankiales	201174|Actinobacteria	G	PFAM Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
MMS3_k127_1688378_18	1206720.BAFQ01000293_gene6368	2.539e-89	313.0	COG0707@1|root,COG0707@2|Bacteria,2GREI@201174|Actinobacteria	201174|Actinobacteria	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,Glyco_tran_28_C,Glyco_trans_1_4,MGDG_synth,WES_acyltransf
MMS3_k127_1688378_20	876044.IMCC3088_1495	4.281e-78	276.0	2DBBP@1|root,2Z88Z@2|Bacteria,1R3B4@1224|Proteobacteria,1RSHG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
MMS3_k127_1688378_26	392499.Swit_0308	9.795e-48	188.0	COG5361@1|root,COG5361@2|Bacteria,1PF7H@1224|Proteobacteria,2U4QR@28211|Alphaproteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
MMS3_k127_1688378_19	298654.FraEuI1c_4490	7.068e-86	299.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_1688378_35	1464048.JNZS01000004_gene1440	9.326e-12	75.0	2DYMY@1|root,34AD9@2|Bacteria,2I408@201174|Actinobacteria,4DFMF@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
MMS3_k127_1688378_21	1229780.BN381_250045	5.914e-78	283.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
MMS3_k127_1688378_31	1313172.YM304_13340	1.342e-35	143.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
MMS3_k127_1688378_7	106370.Francci3_3219	7.192e-152	496.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4ERZ8@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMS3_k127_1688378_33	675635.Psed_0560	9.411e-23	98.0	COG1141@1|root,COG1141@2|Bacteria,2GT1Y@201174|Actinobacteria	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	fdxD_2	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
MMS3_k127_1688378_1	471852.Tcur_3981	3.117e-182	580.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria,4EHB7@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
MMS3_k127_1688378_9	465541.ATCJ01000005_gene1883	3.214e-130	436.0	COG0183@1|root,COG0183@2|Bacteria,2GNCM@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
MMS3_k127_1688378_25	110319.CF8_2187	6.598e-56	208.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria,4DMZC@85009|Propionibacteriales	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_1688378_28	66875.JODY01000001_gene4853	1.593e-44	172.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_1688378_8	1229780.BN381_80190	3.786e-144	478.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria	201174|Actinobacteria	S	unusual protein kinase	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC1,APH
MMS3_k127_1688378_34	441620.Mpop_0127	8.534e-13	76.0	COG3427@1|root,COG3427@2|Bacteria,1QZZ3@1224|Proteobacteria,2TYH6@28211|Alphaproteobacteria,1JTWX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_1688378_13	1192034.CAP_8821	1.218e-107	361.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria	1224|Proteobacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_1688378_30	105425.BBPL01000040_gene3451	7.517e-38	153.0	2FFMA@1|root,347IQ@2|Bacteria,2H7CE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1688378_5	351607.Acel_2020	1.02e-154	503.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4ERWF@85013|Frankiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
MMS3_k127_1688378_32	1179773.BN6_15500	6.994e-31	132.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4E5KZ@85010|Pseudonocardiales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
MMS3_k127_1688378_12	713586.KB900536_gene2412	5.862e-111	370.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1WWTF@135613|Chromatiales	135613|Chromatiales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
MMS3_k127_1688378_22	419947.MRA_3588	1.327e-73	262.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,2348R@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1688378_16	58123.JOFJ01000013_gene4895	9.642e-100	334.0	COG1024@1|root,COG1024@2|Bacteria,2GN54@201174|Actinobacteria,4EIAR@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA20	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_1688378_14	685727.REQ_00850	2.581e-106	361.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,4FZIK@85025|Nocardiaceae	201174|Actinobacteria	I	Coenzyme A transferase	cotA	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
MMS3_k127_1688378_17	66377.JOBH01000008_gene6744	2.651e-95	321.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria	201174|Actinobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
MMS3_k127_1688378_10	463191.SSEG_08723	1.206e-121	423.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria	201174|Actinobacteria	T	2-nitropropane dioxygenase	fabK	GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007623,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0016192,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034404,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0042278,GO:0042451,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046903,GO:0048511,GO:0050896,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097708,GO:0099503,GO:0101002,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1904813	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
MMS3_k127_1688378_11	1380390.JIAT01000002_gene6003	3.73e-120	422.0	COG0477@1|root,COG0477@2|Bacteria,2HF4N@201174|Actinobacteria,4CPRZ@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1688378_23	469383.Cwoe_0557	1.328e-71	248.0	COG1216@1|root,COG1216@2|Bacteria,2IIII@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1688378_36	1380347.JNII01000010_gene2499	7.465e-07	57.0	2C3UR@1|root,330BB@2|Bacteria,2GU03@201174|Actinobacteria,4EWJB@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1688378_0	1206733.BAGC01000019_gene4526	2.944e-185	592.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4FYZA@85025|Nocardiaceae	201174|Actinobacteria	I	Thiolase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N,ketoacyl-synt
MMS3_k127_1688378_27	1278078.G419_14689	2.356e-45	179.0	COG1545@1|root,COG1545@2|Bacteria,2IFQP@201174|Actinobacteria,4G0JI@85025|Nocardiaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_1688378_6	525909.Afer_0085	2.638e-153	493.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_1688378_4	479433.Caci_1366	3.784e-165	531.0	COG1960@1|root,COG1960@2|Bacteria,2GJA9@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE20	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1688378_24	1229780.BN381_350085	2.073e-59	219.0	COG1960@1|root,COG1960@2|Bacteria,2GKUW@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
MMS3_k127_1717061_5	1313172.YM304_09850	8.156e-100	349.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CMRV@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Histidine kinase	-	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2
MMS3_k127_1717061_4	525909.Afer_0351	1.334e-101	338.0	COG1387@1|root,COG1387@2|Bacteria,2IR14@201174|Actinobacteria,4CNF5@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Histidinol phosphate phosphatase, HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
MMS3_k127_1717061_7	1297742.A176_05538	9.227e-48	179.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,43BAG@68525|delta/epsilon subdivisions,2X6PP@28221|Deltaproteobacteria,2YUZG@29|Myxococcales	28221|Deltaproteobacteria	H	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
MMS3_k127_1717061_1	1229780.BN381_310066	3.453e-138	452.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria	201174|Actinobacteria	D	anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
MMS3_k127_1717061_3	1229780.BN381_310065	3.649e-105	350.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria	201174|Actinobacteria	D	Pfam Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
MMS3_k127_1717061_8	525909.Afer_0348	1.495e-16	81.0	2E3M2@1|root,31DE4@2|Bacteria,2HH0X@201174|Actinobacteria,4CP16@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
MMS3_k127_1717061_0	1313172.YM304_23420	8.114e-141	458.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CMVC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
MMS3_k127_1717061_6	1333998.M2A_1845	1.099e-94	319.0	COG1024@1|root,COG1024@2|Bacteria,1RA5T@1224|Proteobacteria,2UP3E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_1717061_9	1190603.AJYD01000069_gene2347	6.524e-13	72.0	2EGVV@1|root,33AN3@2|Bacteria,1NJ5K@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1717061_10	395964.KE386496_gene958	1.964e-11	75.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,3NBSY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMS3_k127_1717061_2	1313172.YM304_09730	7.62e-118	391.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2GJUZ@201174|Actinobacteria,4CMV4@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
MMS3_k127_1717376_6	469371.Tbis_2431	6.746e-130	424.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4DZJ7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
MMS3_k127_1717376_13	1229780.BN381_330062	2.49e-66	246.0	COG4690@1|root,COG4690@2|Bacteria	2|Bacteria	E	dipeptidase activity	-	-	-	ko:K14358	-	-	-	-	ko00000,ko01002	-	-	-	AAT,Peptidase_C69
MMS3_k127_1717376_21	1229780.BN381_290037	2.639e-20	99.0	COG3247@1|root,COG3247@2|Bacteria	2|Bacteria	U	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
MMS3_k127_1717376_11	1280950.HJO_16065	3.382e-81	289.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
MMS3_k127_1717376_18	1121877.JQKF01000010_gene755	5.333e-27	116.0	COG0694@1|root,COG0694@2|Bacteria,2HGE4@201174|Actinobacteria,4CNCF@84992|Acidimicrobiia	84992|Acidimicrobiia	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
MMS3_k127_1717376_20	656024.FsymDg_0257	8.699e-24	106.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4ET3M@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_1717376_8	1449069.JMLO01000004_gene3655	1.52e-107	370.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4G9I9@85025|Nocardiaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_1717376_19	146922.JOFU01000009_gene946	3.684e-26	113.0	COG2905@1|root,COG2905@2|Bacteria,2IJJ6@201174|Actinobacteria	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMS3_k127_1717376_16	748247.AZKH_4186	9.678e-30	135.0	COG2199@1|root,COG3829@1|root,COG4585@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,1QWNG@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,HATPase_c,Response_reg
MMS3_k127_1717376_15	1385520.N802_09325	8.99e-35	145.0	COG2197@1|root,COG2197@2|Bacteria,2GJ5I@201174|Actinobacteria,4FGZ2@85021|Intrasporangiaceae	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1717376_1	1313172.YM304_10130	7.209e-178	575.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	2|Bacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1717376_4	235985.BBPN01000023_gene2597	6.487e-133	439.0	COG2239@1|root,COG2239@2|Bacteria,2IAC3@201174|Actinobacteria,2NFAR@228398|Streptacidiphilus	201174|Actinobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
MMS3_k127_1717376_3	675635.Psed_0041	3.098e-148	484.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4E050@85010|Pseudonocardiales	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
MMS3_k127_1717376_5	1003195.SCAT_1409	3.482e-132	456.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_1717376_9	471852.Tcur_3659	4.967e-93	318.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4EH41@85012|Streptosporangiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_1717376_7	1050202.KB913024_gene1856	2.208e-113	390.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria,407DJ@622450|Actinopolysporales	201174|Actinobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
MMS3_k127_1717376_12	1050202.KB913024_gene1855	4e-74	257.0	COG4122@1|root,COG4122@2|Bacteria,2GQ0Z@201174|Actinobacteria,4082R@622450|Actinopolysporales	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
MMS3_k127_1717376_0	525909.Afer_0493	4.755e-213	695.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CMSA@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family M1 domain	-	-	-	ko:K08776	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
MMS3_k127_1717376_10	331869.BAL199_11346	3.854e-84	291.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,4BPX1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM pfkB family carbohydrate kinase	pfkB	-	2.7.1.20,2.7.1.4	ko:K00847,ko:K00856	ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100	-	R00185,R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_1717376_2	106370.Francci3_3871	1.244e-151	498.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4ES8Y@85013|Frankiales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
MMS3_k127_1717376_17	1380346.JNIH01000042_gene5545	4.084e-27	119.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
MMS3_k127_1717376_22	1237500.ANBA01000017_gene1803	1.589e-14	76.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
MMS3_k127_1729619_14	1298863.AUEP01000002_gene1537	1.695e-14	83.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4DRPK@85009|Propionibacteriales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
MMS3_k127_1729619_1	1229780.BN381_140005	5.054e-162	518.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,3UW88@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMS3_k127_1729619_9	1229780.BN381_140003	2.858e-37	151.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,3UWPW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Alanine racemase, N-terminal domain	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
MMS3_k127_1729619_12	1229780.BN381_140002	2.926e-26	119.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,3UWTH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
MMS3_k127_1729619_15	471874.PROSTU_00051	1.34e-08	59.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,3Z7MH@586|Providencia	1236|Gammaproteobacteria	S	Psort location CytoplasmicMembrane, score	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
MMS3_k127_1729619_17	1121342.AUCO01000001_gene2205	0.0005702	50.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,36FZ8@31979|Clostridiaceae	186801|Clostridia	D	PFAM DivIVA family protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
MMS3_k127_1729619_10	1121877.JQKF01000014_gene14	7.24e-37	151.0	COG1734@1|root,COG1734@2|Bacteria,2HH4M@201174|Actinobacteria,4CP4R@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1729619_13	1274.HX89_05975	5.524e-17	90.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,1ZW3B@145357|Dermacoccaceae	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
MMS3_k127_1729619_4	1313172.YM304_19580	6.832e-69	253.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CN1X@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
MMS3_k127_1729619_3	525909.Afer_1208	4.475e-81	280.0	COG0568@1|root,COG0568@2|Bacteria,2H445@201174|Actinobacteria,4CNJ9@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_1729619_7	1278073.MYSTI_06691	1.089e-57	209.0	COG0406@1|root,COG0406@2|Bacteria,1RCJE@1224|Proteobacteria,42W6J@68525|delta/epsilon subdivisions,2WSAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
MMS3_k127_1729619_5	1229780.BN381_430076	4.99e-64	222.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
MMS3_k127_1729619_2	1229780.BN381_430074	4.032e-94	323.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,3UWWP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
MMS3_k127_1729619_8	1206101.AZXC01000030_gene1921	6.077e-48	177.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria	201174|Actinobacteria	S	regulation of cellular protein catabolic process	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
MMS3_k127_1729619_0	1121877.JQKF01000027_gene2474	0.0	1488.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CMWT@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA polymerase alpha chain like domain	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
MMS3_k127_1729619_6	1121877.JQKF01000027_gene2478	7.285e-59	211.0	2BWZ3@1|root,33X4C@2|Bacteria,2H5EF@201174|Actinobacteria,4CN6H@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1729619_16	525909.Afer_1632	1.78e-06	60.0	2ANCX@1|root,31DBG@2|Bacteria,2HGYA@201174|Actinobacteria,4CNYJ@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1729619_11	1229780.BN381_430065	7.527e-28	118.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,3UWA8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
MMS3_k127_1760116_3	1476876.JOJO01000005_gene5111	2.218e-111	367.0	COG0561@1|root,COG0561@2|Bacteria,2IA5F@201174|Actinobacteria	201174|Actinobacteria	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
MMS3_k127_1760116_2	1229780.BN381_100139	3.425e-141	464.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,3UW95@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
MMS3_k127_1760116_9	512565.AMIS_80880	7.172e-26	112.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4DCPI@85008|Micromonosporales	201174|Actinobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
MMS3_k127_1760116_11	1121877.JQKF01000007_gene975	2.423e-24	111.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4CN8W@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
MMS3_k127_1760116_5	1229780.BN381_100142	6.398e-60	214.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,3UWQD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Single-strand binding protein family	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
MMS3_k127_1760116_10	1229780.BN381_100143	9.877e-25	108.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,3UWQU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
MMS3_k127_1760116_4	1229780.BN381_100144	9.604e-97	327.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,3UW6F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
MMS3_k127_1760116_7	1313172.YM304_42670	4.047e-28	124.0	2CQNK@1|root,332VM@2|Bacteria,2HGHQ@201174|Actinobacteria,4CNEW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
MMS3_k127_1760116_8	1380347.JNII01000011_gene855	3.183e-26	115.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria,4ESIA@85013|Frankiales	201174|Actinobacteria	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
MMS3_k127_1760116_0	525909.Afer_0037	7.64e-179	569.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CNE8@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
MMS3_k127_1760116_6	1122604.JONR01000003_gene1577	2.35e-34	137.0	COG2128@1|root,COG2128@2|Bacteria,1N8NE@1224|Proteobacteria,1T0ZK@1236|Gammaproteobacteria,1XA8E@135614|Xanthomonadales	135614|Xanthomonadales	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_1760116_1	1157637.KB892093_gene6664	2.11e-159	514.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
MMS3_k127_1763456_8	1449069.JMLO01000008_gene3497	2.543e-62	227.0	COG1028@1|root,COG1028@2|Bacteria,2GMAG@201174|Actinobacteria,4FU2T@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1763456_16	596151.DesfrDRAFT_1371	7.068e-16	82.0	2F2Z4@1|root,2ZW38@2|Bacteria,1Q0DJ@1224|Proteobacteria,436IR@68525|delta/epsilon subdivisions,2X157@28221|Deltaproteobacteria,2ME98@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1763456_0	1380356.JNIK01000002_gene4784	2.937e-136	447.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,4EUN0@85013|Frankiales	201174|Actinobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_1763456_5	1380356.JNIK01000013_gene3959	1.06e-95	326.0	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria,4ETZK@85013|Frankiales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_1763456_13	208444.JNYY01000001_gene4757	9.249e-25	119.0	COG1309@1|root,COG1309@2|Bacteria,2IKG3@201174|Actinobacteria,4EEZ7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1763456_14	1223523.H340_06796	8.776e-22	103.0	COG3945@1|root,COG3945@2|Bacteria,2IIV6@201174|Actinobacteria	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
MMS3_k127_1763456_9	585531.HMPREF0063_12379	2.045e-52	199.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4DPX7@85009|Propionibacteriales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_1763456_15	397278.JOJN01000003_gene1816	5.188e-19	92.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria,4DRP0@85009|Propionibacteriales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_1763456_2	887062.HGR_05449	1.198e-127	420.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,4AAI7@80864|Comamonadaceae	28216|Betaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
MMS3_k127_1763456_11	666685.R2APBS1_0201	5.52e-45	176.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1X449@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
MMS3_k127_1763456_4	1283299.AUKG01000004_gene1116	3.005e-99	340.0	COG2230@1|root,COG2230@2|Bacteria,2GM5H@201174|Actinobacteria,4CSA0@84995|Rubrobacteria	84995|Rubrobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
MMS3_k127_1763456_6	1429851.X548_09270	1.336e-81	298.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1X4PF@135614|Xanthomonadales	135614|Xanthomonadales	I	fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
MMS3_k127_1763456_10	1313172.YM304_29460	5.775e-51	191.0	COG5012@1|root,COG5012@2|Bacteria,2GKAY@201174|Actinobacteria	201174|Actinobacteria	S	Cobalamin B12-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
MMS3_k127_1763456_1	1120934.KB894443_gene4278	2.739e-129	448.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4E2AT@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA,TspO_MBR
MMS3_k127_1763456_3	351607.Acel_0151	6.974e-125	430.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,4ERIM@85013|Frankiales	201174|Actinobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
MMS3_k127_1763456_7	1229780.BN381_80217	1.387e-64	230.0	COG1946@1|root,COG1946@2|Bacteria	2|Bacteria	I	acyl-CoA hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
MMS3_k127_1763456_12	1382304.JNIL01000001_gene2466	2.287e-26	123.0	COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,278XK@186823|Alicyclobacillaceae	91061|Bacilli	I	Acyltransferase family	yvhB	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMS3_k127_1768096_31	1229780.BN381_330070	8.3e-18	91.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,3UW6W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
MMS3_k127_1768096_32	465515.Mlut_07000	5.688e-09	62.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,1WA8F@1268|Micrococcaceae	201174|Actinobacteria	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
MMS3_k127_1768096_5	1229780.BN381_330069	7.541e-146	476.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,3UW9A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
MMS3_k127_1768096_27	1229780.BN381_330068	2.571e-35	142.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria,3UWYK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
MMS3_k127_1768096_1	1380370.JIBA01000015_gene46	8.185e-188	616.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4FF1E@85021|Intrasporangiaceae	201174|Actinobacteria	J	Anticodon binding domain	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
MMS3_k127_1768096_4	525909.Afer_0633	2.827e-181	578.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CMRA@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
MMS3_k127_1768096_21	525909.Afer_0632	6.238e-72	263.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CMZX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
MMS3_k127_1768096_20	1313172.YM304_27440	5.81e-73	250.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CMRC@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
MMS3_k127_1768096_22	1229780.BN381_330056	1.977e-58	210.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,3UWAE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
MMS3_k127_1768096_23	1121877.JQKF01000004_gene1131	1.961e-57	220.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4CN3S@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
MMS3_k127_1768096_24	1121877.JQKF01000004_gene1132	5.246e-55	202.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CN2Z@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
MMS3_k127_1768096_16	1121877.JQKF01000004_gene1133	1.633e-87	297.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CMRF@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
MMS3_k127_1768096_18	525909.Afer_0627	4.563e-83	286.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CMXN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
MMS3_k127_1768096_11	1229780.BN381_330051	2.857e-105	349.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,3UWBA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
MMS3_k127_1768096_19	1313172.YM304_27520	1.526e-75	263.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CN5T@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_1768096_9	1120936.KB907209_gene1795	7.215e-112	381.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4EMZ3@85012|Streptosporangiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_1768096_12	1313172.YM304_19260	9.78e-99	327.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1768096_15	351607.Acel_1831	1.3e-92	322.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria,4ERY7@85013|Frankiales	201174|Actinobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1768096_33	479434.Sthe_0621	6.717e-07	61.0	COG5401@1|root,COG5401@2|Bacteria,2GA61@200795|Chloroflexi,27Y9M@189775|Thermomicrobia	189775|Thermomicrobia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
MMS3_k127_1768096_29	1384484.AEQU_1296	1.032e-20	103.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CVU7@84998|Coriobacteriia	84998|Coriobacteriia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
MMS3_k127_1768096_26	479433.Caci_7259	1.068e-38	152.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS3_k127_1768096_0	1313172.YM304_26780	8.928e-200	631.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4CMTE@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Class-II DAHP synthetase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
MMS3_k127_1768096_17	1246995.AFR_04305	8.18e-86	305.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1768096_13	1123023.JIAI01000002_gene5557	2.258e-97	324.0	COG0030@1|root,COG0030@2|Bacteria,2GIZ8@201174|Actinobacteria,4DYTH@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS3_k127_1768096_30	1283299.AUKG01000003_gene359	2.215e-19	97.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_1768096_28	1128421.JAGA01000003_gene3442	3.964e-30	129.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.85,5.4.2.11,5.4.2.12	ko:K01834,ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
MMS3_k127_1768096_2	1229780.BN381_10220	2.411e-187	605.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,3UX9M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
MMS3_k127_1768096_6	1229780.BN381_10219	3.272e-133	432.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,3UX3U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
MMS3_k127_1768096_8	365528.KB891102_gene4572	6.862e-128	427.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4ERK4@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
MMS3_k127_1768096_14	1229780.BN381_10208	4.143e-96	340.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,3UWHH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
MMS3_k127_1768096_7	1229780.BN381_10207	7.042e-133	449.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,3UWET@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
MMS3_k127_1768096_10	1123023.JIAI01000005_gene619	5.797e-108	364.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4E0CV@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMS3_k127_1768096_25	1229780.BN381_100035	2.378e-53	197.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,3UWQY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Helix-turn-helix diphteria tox regulatory element	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
MMS3_k127_1768096_3	102129.Lepto7375DRAFT_8407	3.424e-184	586.0	COG3733@1|root,COG3733@2|Bacteria,1G2YB@1117|Cyanobacteria,1HE6W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Copper amine oxidase, enzyme domain	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
MMS3_k127_1794635_7	1394178.AWOO02000043_gene5879	4.776e-13	71.0	COG3550@1|root,COG3550@2|Bacteria,2GJ1X@201174|Actinobacteria,4EJXI@85012|Streptosporangiales	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
MMS3_k127_1794635_2	67257.JODR01000034_gene1441	1.743e-107	365.0	COG1804@1|root,COG1804@2|Bacteria,2I9RM@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_1794635_4	1242864.D187_009655	4.579e-32	136.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria	1224|Proteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
MMS3_k127_1794635_5	1278078.G419_15728	5.851e-17	96.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4FX40@85025|Nocardiaceae	201174|Actinobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMS3_k127_1794635_3	439481.Aboo_0278	2.767e-96	331.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota,3F317@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Amino acid permease	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	AA_permease_2,NTP_transf_2
MMS3_k127_1794635_6	1206729.BAFZ01000032_gene767	1.439e-13	80.0	2AQ4G@1|root,31F9R@2|Bacteria,2HCQ3@201174|Actinobacteria,4G4H5@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1794635_1	36809.MAB_3637c	1.205e-108	366.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria,233GC@1762|Mycobacteriaceae	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_1794635_0	247633.GP2143_17446	9.69e-231	719.0	COG1960@1|root,COG1960@2|Bacteria,1MWUU@1224|Proteobacteria	1224|Proteobacteria	I	acyl-CoA dehydrogenase	MA20_16360	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1799021_6	298655.KI912267_gene6926	1.251e-152	494.0	COG2159@1|root,COG2159@2|Bacteria,2I9QG@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_1799021_2	1268303.RHODMAR_3384	1.002e-217	693.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4FYXG@85025|Nocardiaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
MMS3_k127_1799021_5	1172180.KB911799_gene1958	1.655e-166	539.0	COG1680@1|root,COG1680@2|Bacteria,2GNNF@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
MMS3_k127_1799021_9	402881.Plav_2411	7.041e-113	373.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2U14P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1799021_19	557599.MKAN_06020	1.089e-28	125.0	2B21F@1|root,31UIA@2|Bacteria,2GU1R@201174|Actinobacteria,23BK8@1762|Mycobacteriaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_1799021_12	525368.HMPREF0591_5373	1.995e-66	237.0	COG1028@1|root,COG1028@2|Bacteria,2IAKC@201174|Actinobacteria,2378T@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1799021_18	1394178.AWOO02000024_gene5603	1.21e-37	158.0	COG1309@1|root,COG1309@2|Bacteria,2IMF7@201174|Actinobacteria,4EJQ8@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1799021_4	222534.KB893772_gene4664	1.72e-176	569.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1799021_21	224911.27351163	5.529e-17	86.0	COG1141@1|root,COG1141@2|Bacteria,1MZJU@1224|Proteobacteria,2UCKK@28211|Alphaproteobacteria,3K07G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	MA20_16570	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
MMS3_k127_1799021_7	1230476.C207_00128	1.45e-127	420.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TR6X@28211|Alphaproteobacteria,3JU3Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Cytochrome P450	CYP127A	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_1799021_11	326424.FRAAL5547	4.588e-79	274.0	COG1024@1|root,COG1024@2|Bacteria,2IGUN@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_1799021_20	1032480.MLP_28880	3.452e-26	119.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	XK27_05885	-	2.3.1.82	ko:K03825,ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_4
MMS3_k127_1799021_10	1313172.YM304_41520	1.184e-103	343.0	COG5285@1|root,COG5285@2|Bacteria,2GNXP@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
MMS3_k127_1799021_13	196162.Noca_2187	3.101e-58	211.0	2F13R@1|root,33U56@2|Bacteria,2IGDX@201174|Actinobacteria,4DRDR@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
MMS3_k127_1799021_17	1158050.KB895460_gene3085	2.943e-38	145.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria	201174|Actinobacteria	K	arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_1799021_16	1158050.KB895460_gene3084	1.767e-42	166.0	COG3832@1|root,COG3832@2|Bacteria,2ITEM@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMS3_k127_1799021_15	1157637.KB892102_gene1570	1.4e-51	193.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
MMS3_k127_1799021_14	298655.KI912266_gene5957	1.058e-54	201.0	COG1545@1|root,COG1545@2|Bacteria,2IFHZ@201174|Actinobacteria	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	-	-	-	-	-	-	-	-	-	OB_aCoA_assoc
MMS3_k127_1799021_3	298655.KI912266_gene5958	2.518e-203	640.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_1799021_0	298654.FraEuI1c_3419	4.048e-293	929.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
MMS3_k127_1799021_1	1123320.KB889668_gene3366	1.887e-265	837.0	COG0410@1|root,COG0477@1|root,COG0410@2|Bacteria,COG2814@2|Bacteria,2IH81@201174|Actinobacteria	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,MFS_1
MMS3_k127_1799021_8	298654.FraEuI1c_3890	1.042e-126	408.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria,4EVT2@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMS3_k127_1889896_0	525909.Afer_0713	0.0	1147.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4CMQ1@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
MMS3_k127_1889896_2	397278.JOJN01000002_gene644	2.638e-50	186.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4DR5Z@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
MMS3_k127_1889896_1	1229780.BN381_210107	2.244e-177	569.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,3UWCV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_1889896_3	1157640.AQWO01000009_gene520	4.02e-35	139.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_1941003_5	1463920.JOGB01000060_gene4786	8.135e-87	308.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS3_k127_1941003_0	1156844.KB891797_gene5575	1.318e-239	761.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria	201174|Actinobacteria	C	CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
MMS3_k127_1941003_7	1283283.ATXA01000014_gene3590	9.972e-41	170.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_1941003_2	1283287.KB822578_gene2556	1.211e-163	534.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
MMS3_k127_1941003_3	1313172.YM304_22570	1.147e-122	402.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CMPY@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
MMS3_k127_1941003_4	1341646.CBMO010000079_gene371	1.682e-103	346.0	COG1024@1|root,COG1024@2|Bacteria,2IBN1@201174|Actinobacteria,237N9@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_1941003_1	875328.JDM601_1093	4.361e-195	616.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,234DD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_1941003_6	321327.CYA_1193	4.211e-73	255.0	COG0740@1|root,COG0740@2|Bacteria,1G1TB@1117|Cyanobacteria,1GZ38@1129|Synechococcus	1117|Cyanobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP2	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_1941003_9	1123024.AUII01000007_gene4839	1.125e-19	91.0	COG3620@1|root,COG3620@2|Bacteria,2GTMF@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMS3_k127_1941003_8	134676.ACPL_1841	3.21e-23	109.0	COG0740@1|root,COG0740@2|Bacteria,2GPTS@201174|Actinobacteria,4DF0Y@85008|Micromonosporales	201174|Actinobacteria	OU	Belongs to the peptidase S14 family	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_2029390_7	1430440.MGMSRv2_4169	1.283e-46	173.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TT4A@28211|Alphaproteobacteria,2JRFR@204441|Rhodospirillales	204441|Rhodospirillales	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_2029390_2	43759.JNWK01000016_gene312	3.808e-162	529.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE30	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2029390_4	561175.KB894098_gene5200	2.7e-101	343.0	COG1028@1|root,COG1028@2|Bacteria,2GN3D@201174|Actinobacteria,4EFK1@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_2029390_1	1463920.JOGB01000060_gene4805	2.366e-187	601.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD16	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2029390_3	1123319.AUBE01000002_gene1509	1.41e-126	414.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_2029390_6	330214.NIDE3016	7.153e-82	279.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_2029390_5	365528.KB891209_gene2164	4.106e-91	310.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,4ESHX@85013|Frankiales	201174|Actinobacteria	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_2029390_8	1120934.KB894410_gene6977	9.627e-44	179.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4DYBQ@85010|Pseudonocardiales	201174|Actinobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_2029390_0	525909.Afer_0479	3.119e-223	710.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CMS4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
MMS3_k127_2029390_11	479434.Sthe_2692	8.213e-20	104.0	COG0738@1|root,COG0738@2|Bacteria,2G85V@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2029390_10	1313172.YM304_10880	2.077e-28	122.0	COG5496@1|root,COG5496@2|Bacteria,2IKZP@201174|Actinobacteria	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_2029390_9	1313172.YM304_10890	4.707e-41	164.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4CNKK@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMS3_k127_20354_5	645465.ACUR01000575_gene1381	1.354e-127	420.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,2I931@201174|Actinobacteria	201174|Actinobacteria	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
MMS3_k127_20354_24	298654.FraEuI1c_3299	3.119e-20	100.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	ydgC	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_20354_15	47763.JNZA01000002_gene3411	1.887e-48	185.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
MMS3_k127_20354_26	979556.MTES_1231	0.0001325	51.0	COG3194@1|root,COG3194@2|Bacteria,2GXIW@201174|Actinobacteria	201174|Actinobacteria	F	Ureidoglycolate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Ureidogly_lyase
MMS3_k127_20354_20	469383.Cwoe_5005	2.607e-28	118.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K03490	-	-	-	-	ko00000,ko03000	-	-	-	Cupin_2
MMS3_k127_20354_7	266117.Rxyl_0619	1.985e-87	298.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CPZ9@84995|Rubrobacteria	84995|Rubrobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_20354_25	1283299.AUKG01000001_gene2616	1.719e-11	79.0	COG4447@1|root,COG4447@2|Bacteria,2GSZJ@201174|Actinobacteria	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_20354_8	134676.ACPL_3897	1.5e-79	301.0	COG0739@1|root,COG2755@1|root,COG3291@1|root,COG0739@2|Bacteria,COG2755@2|Bacteria,COG3291@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_20354_6	469371.Tbis_3219	7.949e-97	324.0	COG0378@1|root,COG0378@2|Bacteria,2HP34@201174|Actinobacteria,4DYGC@85010|Pseudonocardiales	201174|Actinobacteria	KO	TIGRFAM Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
MMS3_k127_20354_22	1150599.MPHLEI_15381	7.038e-23	114.0	COG0375@1|root,COG0375@2|Bacteria,2IKYY@201174|Actinobacteria,23F39@1762|Mycobacteriaceae	201174|Actinobacteria	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
MMS3_k127_20354_4	1172180.KB911777_gene1524	2.612e-135	443.0	COG2042@1|root,COG3376@2|Bacteria,2GJZB@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the NiCoT transporter (TC 2.A.52) family	nicT	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
MMS3_k127_20354_19	525909.Afer_0199	1.012e-33	137.0	COG0735@1|root,COG0735@2|Bacteria,2HGZ6@201174|Actinobacteria,4CNZA@84992|Acidimicrobiia	84992|Acidimicrobiia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMS3_k127_20354_27	387093.SUN_1070	0.0006033	49.0	COG2353@1|root,COG2353@2|Bacteria,1PDM9@1224|Proteobacteria,42TFW@68525|delta/epsilon subdivisions,2YQ0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
MMS3_k127_20354_21	208444.JNYY01000034_gene2600	1.705e-26	110.0	COG0298@1|root,COG0298@2|Bacteria,2IRJ9@201174|Actinobacteria,4E5W4@85010|Pseudonocardiales	201174|Actinobacteria	O	Hydrogenase assembly chaperone hypC hupF	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
MMS3_k127_20354_1	469371.Tbis_3236	2.031e-198	625.0	COG0409@1|root,COG0409@2|Bacteria,2GMHA@201174|Actinobacteria,4DYZ6@85010|Pseudonocardiales	201174|Actinobacteria	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
MMS3_k127_20354_0	710111.FraQA3DRAFT_2670	1.022e-253	807.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
MMS3_k127_20354_10	1150599.MPHLEI_15441	1.026e-69	244.0	COG0279@1|root,COG0279@2|Bacteria,2GMKE@201174|Actinobacteria,2349G@1762|Mycobacteriaceae	201174|Actinobacteria	G	HupF/HypC family	-	-	-	-	-	-	-	-	-	-	-	-	HupF_HypC
MMS3_k127_20354_11	935866.JAER01000029_gene1441	2.131e-68	239.0	COG0279@1|root,COG0279@2|Bacteria,2GM2Q@201174|Actinobacteria,4DS8W@85009|Propionibacteriales	201174|Actinobacteria	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
MMS3_k127_20354_3	1429046.RR21198_4164	2.519e-142	471.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria,4FTY3@85025|Nocardiaceae	201174|Actinobacteria	O	AIR synthase related protein, C-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
MMS3_k127_20354_13	522306.CAP2UW1_2989	7.038e-51	189.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2VICR@28216|Betaproteobacteria,1KQY8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
MMS3_k127_20354_18	196490.AUEZ01000036_gene6081	1.278e-34	145.0	COG3828@1|root,COG3828@2|Bacteria,1R5XA@1224|Proteobacteria,2U51F@28211|Alphaproteobacteria,3K5VQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	GSDH,ThuA
MMS3_k127_20354_14	1040983.AXAE01000013_gene5866	1.466e-50	193.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2U1S4@28211|Alphaproteobacteria,43NMJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_20354_17	935840.JAEQ01000020_gene2289	2.638e-37	149.0	COG0251@1|root,COG0251@2|Bacteria,1RG19@1224|Proteobacteria,2U6BH@28211|Alphaproteobacteria,43NM8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
MMS3_k127_20354_9	44454.NF84_20400	1.919e-74	259.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,235JB@1762|Mycobacteriaceae	201174|Actinobacteria	G	Aldolase	fucA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	4.1.1.104,4.1.2.17,5.1.3.4	ko:K01628,ko:K03077,ko:K22130	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
MMS3_k127_20354_12	1415779.JOMH01000001_gene676	1.014e-67	242.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RRVQ@1236|Gammaproteobacteria,1X4R1@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
MMS3_k127_20354_2	388051.AUFE01000007_gene1519	2.93e-189	602.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHQD@28216|Betaproteobacteria,1K09N@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Aldehyde dehydrogenase	betB	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_20354_16	525909.Afer_1069	9.513e-46	175.0	2EFBW@1|root,3394U@2|Bacteria,2H758@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_20354_23	35754.JNYJ01000007_gene2895	2.167e-20	101.0	COG4188@1|root,COG4188@2|Bacteria,2I9HM@201174|Actinobacteria,4D9BG@85008|Micromonosporales	201174|Actinobacteria	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2,PAF-AH_p_II
MMS3_k127_2055547_14	351607.Acel_0042	4.507e-40	153.0	COG1765@1|root,COG1765@2|Bacteria,2HA74@201174|Actinobacteria	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS3_k127_2055547_17	196162.Noca_0142	2.465e-23	108.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,4DUJI@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
MMS3_k127_2055547_18	1214242.B446_29585	1.942e-11	69.0	2AY0M@1|root,33ZNP@2|Bacteria,2I85A@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
MMS3_k127_2055547_9	1449346.JQMO01000003_gene2371	2.504e-56	205.0	2BVHU@1|root,32QW6@2|Bacteria	2|Bacteria	S	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
MMS3_k127_2055547_15	1068980.ARVW01000001_gene4142	2.451e-38	147.0	COG2050@1|root,COG2050@2|Bacteria,2IQXX@201174|Actinobacteria,4EEZM@85010|Pseudonocardiales	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_2055547_7	1150398.JIBJ01000006_gene3692	9.134e-78	274.0	COG1409@1|root,COG3511@1|root,COG1409@2|Bacteria,COG3511@2|Bacteria,2II4P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
MMS3_k127_2055547_6	1121945.ATXS01000007_gene506	8.355e-80	288.0	COG1501@1|root,arCOG03663@2157|Archaea,2XV49@28890|Euryarchaeota,23V0G@183963|Halobacteria	183963|Halobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
MMS3_k127_2055547_5	1211815.CBYP010000014_gene3514	2.287e-86	299.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
MMS3_k127_2055547_16	436229.JOEH01000016_gene7349	1.828e-37	145.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria,2NIUJ@228398|Streptacidiphilus	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
MMS3_k127_2055547_4	477641.MODMU_2709	4.21e-98	337.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4ETSH@85013|Frankiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
MMS3_k127_2055547_1	1173028.ANKO01000058_gene3036	2.434e-144	492.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_7,PAS_8,PAS_9,Response_reg
MMS3_k127_2055547_8	469383.Cwoe_5529	7.679e-64	230.0	COG2755@1|root,COG2755@2|Bacteria,2HRH4@201174|Actinobacteria,4CTGS@84995|Rubrobacteria	84995|Rubrobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMS3_k127_2055547_12	1122182.KB903820_gene68	9.106e-46	179.0	2CCFM@1|root,33T1W@2|Bacteria,2IA4M@201174|Actinobacteria,4DI3H@85008|Micromonosporales	201174|Actinobacteria	S	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
MMS3_k127_2055547_3	479431.Namu_2606	9.924e-100	337.0	COG1881@1|root,COG1881@2|Bacteria,2IRRV@201174|Actinobacteria	201174|Actinobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
MMS3_k127_2055547_2	1116232.AHBF01000066_gene8712	1.028e-105	356.0	COG5285@1|root,COG5285@2|Bacteria,2GP1T@201174|Actinobacteria	201174|Actinobacteria	Q	ectoine hydroxylase	ectD	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
MMS3_k127_2055547_10	58123.JOFJ01000001_gene2915	2.043e-53	194.0	COG1917@1|root,COG1917@2|Bacteria,2IFAP@201174|Actinobacteria,4EP9B@85012|Streptosporangiales	201174|Actinobacteria	S	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
MMS3_k127_2055547_0	1003195.SCAT_1065	4.276e-178	570.0	COG0160@1|root,COG0160@2|Bacteria,2GKUY@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ectB	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_2055547_11	561175.KB894098_gene5301	2.783e-46	172.0	COG0454@1|root,COG0456@2|Bacteria,2IMKZ@201174|Actinobacteria,4EPAB@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	ectA	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
MMS3_k127_2055547_13	1246995.AFR_04305	3.017e-43	177.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2135296_16	1298867.AUES01000019_gene3451	1.505e-18	93.0	COG1752@1|root,COG1752@2|Bacteria,1MX8Y@1224|Proteobacteria,2TVP9@28211|Alphaproteobacteria,3JS3R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMS3_k127_2135296_0	1380390.JIAT01000009_gene522	9.525e-268	850.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_2135296_14	292564.Cyagr_2573	5.008e-36	157.0	COG0346@1|root,COG0346@2|Bacteria,1GHNQ@1117|Cyanobacteria,22TQC@167375|Cyanobium	1117|Cyanobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
MMS3_k127_2135296_13	525909.Afer_1936	2.523e-37	152.0	COG0500@1|root,COG0500@2|Bacteria,2I6VV@201174|Actinobacteria,4CNCW@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2135296_15	1500890.JQNL01000001_gene2344	1.585e-28	130.0	arCOG08211@1|root,2ZBM3@2|Bacteria,1RIRV@1224|Proteobacteria,1SFXN@1236|Gammaproteobacteria,1X59H@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2135296_5	656024.FsymDg_4194	1.236e-96	331.0	COG0454@1|root,COG0464@1|root,COG0456@2|Bacteria,COG0464@2|Bacteria,2GJ07@201174|Actinobacteria	201174|Actinobacteria	KO	Belongs to the AAA ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Acetyltransf_1
MMS3_k127_2135296_4	204669.Acid345_2424	1.286e-107	356.0	COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria,2JME1@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
MMS3_k127_2135296_3	1211815.CBYP010000002_gene1985	1.186e-110	374.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4ES50@85013|Frankiales	201174|Actinobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2135296_2	1156844.KB891804_gene2122	5.888e-131	437.0	COG0477@1|root,COG0477@2|Bacteria,2I31V@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2135296_17	1227499.C493_20496	1.718e-05	57.0	COG0346@1|root,arCOG02708@2157|Archaea,2XYA4@28890|Euryarchaeota,23WB3@183963|Halobacteria	183963|Halobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
MMS3_k127_2135296_9	235985.BBPN01000004_gene3169	3.735e-61	218.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,2NHGV@228398|Streptacidiphilus	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMS3_k127_2135296_12	1394178.AWOO02000001_gene1326	1.159e-49	196.0	COG2159@1|root,COG2159@2|Bacteria,2H2CJ@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2135296_6	1313172.YM304_02490	1.678e-91	310.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CN0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
MMS3_k127_2135296_10	1254432.SCE1572_12410	1.006e-55	205.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria,2YUU1@29|Myxococcales	28221|Deltaproteobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
MMS3_k127_2135296_7	287986.DV20_09415	8.467e-85	305.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria,4E10F@85010|Pseudonocardiales	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
MMS3_k127_2135296_1	1123320.KB889686_gene602	3.914e-180	574.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	ddc	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
MMS3_k127_2135296_11	861299.J421_4122	6.725e-53	193.0	COG2761@1|root,COG2761@2|Bacteria,1ZUZU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
MMS3_k127_2135296_8	1394178.AWOO02000030_gene4679	6.128e-82	283.0	COG0154@1|root,COG0154@2|Bacteria,2GSBS@201174|Actinobacteria	201174|Actinobacteria	J	Allophanate hydrolase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433,ko:K21801	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_2167266_6	1144310.PMI07_006451	4.645e-27	115.0	COG1545@1|root,COG1545@2|Bacteria,1MYQ5@1224|Proteobacteria	1224|Proteobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_2167266_3	426355.Mrad2831_2914	2.146e-62	231.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,1JTCM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_2167266_4	309801.trd_1761	4.105e-36	154.0	COG1804@1|root,COG1804@2|Bacteria,2GB4P@200795|Chloroflexi,27XYZ@189775|Thermomicrobia	189775|Thermomicrobia	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_2167266_2	1394178.AWOO02000013_gene7854	1.178e-68	246.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4EGFJ@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2167266_5	1121933.AUHH01000006_gene677	6.407e-33	141.0	COG1545@1|root,COG1545@2|Bacteria,2HQJV@201174|Actinobacteria,4DW22@85009|Propionibacteriales	2|Bacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_2167266_1	1121933.AUHH01000006_gene678	5.298e-146	473.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,4DWU6@85009|Propionibacteriales	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2167266_0	1207063.P24_13673	1.263e-229	722.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,2JQSB@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
MMS3_k127_2167266_7	1380408.AVGH01000005_gene2594	0.0002045	45.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,21WKK@150247|Anoxybacillus	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	kipR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
MMS3_k127_2228639_11	1313172.YM304_20150	8.477e-32	128.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CNDQ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Cytidylate kinase	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
MMS3_k127_2228639_8	1313172.YM304_20160	3.72e-45	174.0	COG0204@1|root,COG0204@2|Bacteria,2HG51@201174|Actinobacteria,4CN6X@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS3_k127_2228639_5	994479.GL877878_gene698	9.88e-63	227.0	COG1215@1|root,COG1215@2|Bacteria,2I3M7@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_2228639_7	502025.Hoch_1760	1.758e-53	204.0	COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria	1224|Proteobacteria	S	Phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMS3_k127_2228639_4	1313172.YM304_25520	5.206e-136	441.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CMP7@84992|Acidimicrobiia	84992|Acidimicrobiia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS3_k127_2228639_2	1229780.BN381_40071	2.293e-151	508.0	COG1625@1|root,COG1625@2|Bacteria,2H3RR@201174|Actinobacteria	201174|Actinobacteria	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
MMS3_k127_2228639_1	1229780.BN381_40072	4.331e-152	496.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,3UWEY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
MMS3_k127_2228639_6	298655.KI912266_gene5278	4.787e-62	218.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4EVCG@85013|Frankiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	gca	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep
MMS3_k127_2228639_0	235985.BBPN01000003_gene4704	1.936e-166	535.0	COG3511@1|root,COG3511@2|Bacteria,2IC2P@201174|Actinobacteria,2NGY0@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
MMS3_k127_2228639_3	247634.GPB2148_1166	1.305e-139	457.0	COG0657@1|root,COG0657@2|Bacteria,1NRN8@1224|Proteobacteria,1SK0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMS3_k127_2228639_9	1122137.AQXF01000002_gene47	9.996e-45	180.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MX32@1224|Proteobacteria,2U3N1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
MMS3_k127_2228639_10	234267.Acid_2066	4.251e-38	162.0	2E5CS@1|root,3304U@2|Bacteria,3Y7FM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_224016_3	543632.JOJL01000027_gene2599	4.448e-55	197.0	COG2030@1|root,COG2030@2|Bacteria,2GIXP@201174|Actinobacteria,4DE8G@85008|Micromonosporales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMS3_k127_224016_1	1229780.BN381_450029	2.342e-66	239.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,3UWS5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
MMS3_k127_224016_4	1312954.KI914847_gene1632	5.148e-46	180.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,1W8VB@1268|Micrococcaceae	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
MMS3_k127_224016_2	1380354.JIAN01000005_gene1823	1.384e-65	242.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4F0JA@85016|Cellulomonadaceae	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
MMS3_k127_224016_5	1032480.MLP_33830	1.254e-10	65.0	2DREV@1|root,33BF4@2|Bacteria,2ISW7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_224016_6	1048339.KB913029_gene1811	6.946e-09	63.0	COG1848@1|root,COG1848@2|Bacteria,2GUQC@201174|Actinobacteria,4EWYP@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_224016_0	1229780.BN381_80362	1.061e-117	392.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,3UWFF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
MMS3_k127_224016_7	1313172.YM304_22610	1.004e-07	65.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CMYU@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_2406069_96	1283283.ATXA01000007_gene3789	1.332e-52	204.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS3_k127_2406069_38	1380356.JNIK01000002_gene4867	4.007e-164	523.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4ETVC@85013|Frankiales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_2406069_15	298653.Franean1_3331	1.98e-226	715.0	COG2159@1|root,COG2159@2|Bacteria,2IEQP@201174|Actinobacteria,4ETVS@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2406069_43	298653.Franean1_5443	1.569e-152	492.0	COG2124@1|root,COG2124@2|Bacteria,2HMMY@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2406069_113	1160137.KB907308_gene7605	2.261e-37	144.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	M1-770	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMS3_k127_2406069_37	298655.KI912266_gene5991	6.611e-167	534.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
MMS3_k127_2406069_32	298654.FraEuI1c_5454	9.628e-176	557.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2406069_39	1415166.NONO_c61440	5.406e-162	519.0	COG0183@1|root,COG0183@2|Bacteria,2GKWR@201174|Actinobacteria,4FZYS@85025|Nocardiaceae	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_2406069_125	365528.KB891181_gene4698	3.471e-18	100.0	2DS7S@1|root,33EWX@2|Bacteria,2GWXQ@201174|Actinobacteria,4EWUK@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2406069_4	298655.KI912266_gene5986	2.159e-286	888.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_2406069_51	1206720.BAFQ01000053_gene1355	2.181e-133	430.0	COG1028@1|root,COG1028@2|Bacteria,2HFNN@201174|Actinobacteria,4FUCT@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_2406069_14	298653.Franean1_6832	5.354e-227	714.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria,4ETQ5@85013|Frankiales	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	OB_aCoA_assoc
MMS3_k127_2406069_90	1160137.KB907307_gene657	3.275e-64	230.0	COG0183@1|root,COG1545@1|root,COG0183@2|Bacteria,COG1545@2|Bacteria,2GKFR@201174|Actinobacteria,4FZ4T@85025|Nocardiaceae	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	OB_aCoA_assoc
MMS3_k127_2406069_35	298655.KI912266_gene5391	2.657e-170	554.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_2406069_10	1160137.KB907307_gene655	4.937e-233	732.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FTXB@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_2406069_16	1206720.BAFQ01000053_gene1354	1.2e-216	681.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4G06W@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2406069_12	1160137.KB907307_gene608	2.308e-231	726.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4FXFM@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2406069_103	1206720.BAFQ01000053_gene1367	4.301e-46	170.0	COG3631@1|root,COG3631@2|Bacteria,2IGCY@201174|Actinobacteria,4G2CW@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMS3_k127_2406069_68	298653.Franean1_6854	7.158e-94	313.0	COG1309@1|root,COG1309@2|Bacteria,2GTK8@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2406069_40	298653.Franean1_6841	1.627e-157	505.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_2406069_45	1160137.KB907307_gene658	4.482e-139	448.0	COG2141@1|root,COG2141@2|Bacteria,2ICP1@201174|Actinobacteria,4FY6B@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2406069_2	365528.KB891181_gene4718	0.0	1053.0	COG1804@1|root,COG1804@2|Bacteria,2GQZU@201174|Actinobacteria,4EUQR@85013|Frankiales	201174|Actinobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_2406069_123	1415166.NONO_c61470	7.464e-19	88.0	COG1141@1|root,COG1141@2|Bacteria,2GWHY@201174|Actinobacteria,4G4BS@85025|Nocardiaceae	201174|Actinobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
MMS3_k127_2406069_25	222534.KB893722_gene511	3.22e-188	597.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
MMS3_k127_2406069_60	1206729.BAFZ01000159_gene6398	3.482e-103	343.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4FUY7@85025|Nocardiaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
MMS3_k127_2406069_29	164757.Mjls_4783	5.781e-184	596.0	COG1960@1|root,COG1960@2|Bacteria,2GP53@201174|Actinobacteria,234QY@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2406069_56	1160137.KB907307_gene604	9.781e-111	373.0	COG1960@1|root,COG1960@2|Bacteria,2GIXH@201174|Actinobacteria,4FV02@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
MMS3_k127_2406069_21	298653.Franean1_6848	1.333e-198	632.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2406069_63	222534.KB893720_gene829	8.98e-100	340.0	COG1960@1|root,COG1960@2|Bacteria,2GM4S@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
MMS3_k127_2406069_23	298655.KI912266_gene5997	1.421e-189	599.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_2406069_0	1206720.BAFQ01000053_gene1350	0.0	1431.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,2GKBW@201174|Actinobacteria,4FUYI@85025|Nocardiaceae	201174|Actinobacteria	C	ferredoxin, Oxidoreductase	-	-	1.2.7.8	ko:K00179,ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR,POR_N,TPP_enzyme_C
MMS3_k127_2406069_94	365528.KB891224_gene1384	7.015e-58	217.0	2F365@1|root,33W0Q@2|Bacteria,2H4WA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EthD
MMS3_k127_2406069_114	1122609.AUGT01000003_gene2437	9.923e-29	124.0	COG3409@1|root,COG3409@2|Bacteria,2IFDD@201174|Actinobacteria	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	Germane
MMS3_k127_2406069_76	1108045.GORHZ_118_00650	1.97e-76	276.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4GE2H@85026|Gordoniaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS3_k127_2406069_49	298655.KI912267_gene7811	7.624e-136	450.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4ETDE@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
MMS3_k127_2406069_24	1246995.AFR_24670	2.542e-188	602.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DDQQ@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	stp	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2406069_112	365528.KB891212_gene2305	2.513e-39	157.0	COG3461@1|root,COG3461@2|Bacteria,2GZN9@201174|Actinobacteria	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
MMS3_k127_2406069_62	298653.Franean1_2248	5.02e-101	337.0	COG1659@1|root,COG1659@2|Bacteria,2GJMK@201174|Actinobacteria,4EUBB@85013|Frankiales	201174|Actinobacteria	S	Encapsulating protein for peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Linocin_M18
MMS3_k127_2406069_17	298653.Franean1_7182	5.843e-215	674.0	COG2159@1|root,COG2159@2|Bacteria,2GKAB@201174|Actinobacteria,4ETXR@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2406069_106	1121272.KB903292_gene3948	7.863e-43	177.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMS3_k127_2406069_72	1160137.KB907307_gene3334	3.954e-88	318.0	COG2050@1|root,COG2050@2|Bacteria,2H2K4@201174|Actinobacteria,4FXGH@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_2406069_109	103733.JNYO01000012_gene2614	2.413e-40	165.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4DZV2@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
MMS3_k127_2406069_95	935839.JAGJ01000001_gene1033	8.018e-56	205.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4F4CP@85017|Promicromonosporaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
MMS3_k127_2406069_92	1121933.AUHH01000006_gene699	7.908e-60	213.0	COG2259@1|root,COG2259@2|Bacteria,2IJ0I@201174|Actinobacteria,4DRJ9@85009|Propionibacteriales	201174|Actinobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
MMS3_k127_2406069_50	365528.KB891226_gene1281	6.201e-134	431.0	COG1028@1|root,COG1028@2|Bacteria,2GKJD@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_2406069_28	298653.Franean1_4320	1.81e-187	598.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,4EUN3@85013|Frankiales	201174|Actinobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_2406069_55	365528.KB891209_gene2153	9.815e-115	391.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4ESNW@85013|Frankiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_2406069_33	285535.JOEY01000006_gene8125	2.233e-174	561.0	COG3173@1|root,COG3173@2|Bacteria,2GJ58@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_2406069_7	710685.MycrhN_3972	4.297e-252	781.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,232CR@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2406069_87	298654.FraEuI1c_5380	1.068e-65	251.0	COG1309@1|root,COG1309@2|Bacteria,2IAMN@201174|Actinobacteria,4EVV6@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2406069_47	1160137.KB907307_gene4082	1.14e-137	441.0	COG1024@1|root,COG1024@2|Bacteria,2GNZE@201174|Actinobacteria,4FUSQ@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_2406069_79	485913.Krac_4850	5.324e-74	265.0	COG0657@1|root,COG0657@2|Bacteria,2G81J@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
MMS3_k127_2406069_59	298655.KI912266_gene5952	8.936e-104	344.0	COG1946@1|root,COG1946@2|Bacteria,2GZFD@201174|Actinobacteria,4EV2I@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
MMS3_k127_2406069_8	298655.KI912266_gene3118	3.392e-251	788.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_2406069_26	298655.KI912266_gene4194	4.764e-188	600.0	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2406069_6	1160137.KB907308_gene7263	1.79e-253	786.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4FUUP@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2406069_48	298653.Franean1_1624	1.443e-137	447.0	COG1960@1|root,COG1960@2|Bacteria,2GNVM@201174|Actinobacteria,4EUAX@85013|Frankiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2406069_30	365528.KB891226_gene1283	2.947e-179	570.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria,4EUGE@85013|Frankiales	201174|Actinobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2406069_53	1160137.KB907307_gene2936	6.465e-128	414.0	COG2267@1|root,COG2267@2|Bacteria,2I5VV@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMS3_k127_2406069_88	298654.FraEuI1c_5432	1.137e-65	238.0	COG1309@1|root,COG1309@2|Bacteria,2GP59@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
MMS3_k127_2406069_3	222534.KB893725_gene263	1.892e-290	899.0	COG0183@1|root,COG1545@1|root,COG0183@2|Bacteria,COG1545@2|Bacteria,2IETY@201174|Actinobacteria,4EXA5@85013|Frankiales	201174|Actinobacteria	I	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_2406069_18	298653.Franean1_3915	2.632e-212	664.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EX8X@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2406069_11	222534.KB893722_gene504	5.346e-232	727.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4EUCK@85013|Frankiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_2406069_91	656024.FsymDg_0458	7.143e-63	242.0	COG1287@1|root,COG1287@2|Bacteria,2HBRT@201174|Actinobacteria,4EXCN@85013|Frankiales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2406069_19	298653.Franean1_4034	8.797e-211	659.0	COG2159@1|root,COG2159@2|Bacteria,2GKAB@201174|Actinobacteria,4ETXR@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2406069_41	931627.MycrhDRAFT_6089	4.626e-154	493.0	COG1024@1|root,COG1024@2|Bacteria,2GKNU@201174|Actinobacteria,233FU@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_2406069_27	1283283.ATXA01000001_gene1189	5.867e-188	611.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EU9P@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
MMS3_k127_2406069_75	1206731.BAGB01000047_gene5181	4.307e-82	286.0	COG3845@1|root,COG3845@2|Bacteria,2I5SB@201174|Actinobacteria	201174|Actinobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
MMS3_k127_2406069_78	1283283.ATXA01000001_gene1187	5.861e-75	269.0	COG3845@1|root,COG3845@2|Bacteria	2|Bacteria	P	ABC transporter	-	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMS3_k127_2406069_120	298654.FraEuI1c_0143	1.38e-21	108.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS3_k127_2406069_69	235985.BBPN01000006_gene3586	1.675e-92	315.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,2NF6J@228398|Streptacidiphilus	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_2406069_44	298653.Franean1_2010	2.257e-145	472.0	COG1946@1|root,COG2343@1|root,COG1946@2|Bacteria,COG2343@2|Bacteria,2GZFD@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3,NTP_transf_9
MMS3_k127_2406069_71	222534.KB893787_gene204	3.614e-88	307.0	COG4221@1|root,COG4221@2|Bacteria,2GK52@201174|Actinobacteria	201174|Actinobacteria	S	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2406069_31	298655.KI912266_gene4542	3.725e-178	568.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4ES22@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
MMS3_k127_2406069_93	1122239.AULS01000002_gene900	2.189e-58	207.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,4FNQJ@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_2406069_13	1313172.YM304_16690	1.172e-229	722.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CMUP@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
MMS3_k127_2406069_111	1313172.YM304_30600	1.287e-39	154.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4CN3T@84992|Acidimicrobiia	201174|Actinobacteria	I	B12 binding domain	icmB	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
MMS3_k127_2406069_66	298655.KI912266_gene2267	2.877e-97	327.0	COG2141@1|root,COG2141@2|Bacteria,2GU1D@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2406069_67	1160718.SU9_00765	2.337e-96	323.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria	201174|Actinobacteria	E	hydrolases or acyltransferases alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMS3_k127_2406069_110	1229780.BN381_640028	9.333e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,2HGC2@201174|Actinobacteria,3UXKK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2406069_102	1333998.M2A_2494	9.229e-47	183.0	2EXDM@1|root,33QQ7@2|Bacteria,1NTQ6@1224|Proteobacteria,2UQVJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2406069_42	1117379.BABA_14322	1.191e-153	498.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2406069_121	930171.Asphe3_29000	2.014e-19	101.0	COG1226@1|root,COG1226@2|Bacteria,2GKNF@201174|Actinobacteria,1W9H1@1268|Micrococcaceae	201174|Actinobacteria	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
MMS3_k127_2406069_118	525909.Afer_1887	1.115e-24	121.0	COG2385@1|root,COG2385@2|Bacteria,2HGNA@201174|Actinobacteria,4CNPA@84992|Acidimicrobiia	84992|Acidimicrobiia	D	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2406069_36	1240349.ANGC01000021_gene3523	7.444e-170	550.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,2GJS0@201174|Actinobacteria,4FX6N@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
MMS3_k127_2406069_86	1206741.BAFX01000061_gene5166	2.435e-67	235.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4FUPK@85025|Nocardiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
MMS3_k127_2406069_97	1041522.MCOL_V204900	6.798e-52	194.0	COG1028@1|root,COG1028@2|Bacteria	1041522.MCOL_V204900|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2406069_52	1214242.B446_29080	4.551e-129	430.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria	201174|Actinobacteria	G	polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
MMS3_k127_2406069_74	1089544.KB912942_gene1783	1.212e-84	298.0	COG1073@1|root,COG1073@2|Bacteria,2IFI1@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_2406069_108	479433.Caci_6418	2.371e-40	157.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria	201174|Actinobacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
MMS3_k127_2406069_119	2002.JOEQ01000015_gene5054	1.878e-23	107.0	COG1396@1|root,COG3467@1|root,COG1396@2|Bacteria,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4EJS7@85012|Streptosporangiales	201174|Actinobacteria	K	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	DUF1918,HTH_3,HTH_31,Pyridox_ox_2
MMS3_k127_2406069_124	1237500.ANBA01000011_gene3395	1.455e-18	94.0	COG1510@1|root,COG1510@2|Bacteria,2HRQN@201174|Actinobacteria,4EPHM@85012|Streptosporangiales	201174|Actinobacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2406069_100	1894.JOER01000017_gene4737	6.623e-51	201.0	COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
MMS3_k127_2406069_99	1313172.YM304_38610	1.008e-51	199.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CNQN@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_2406069_89	66875.JODY01000002_gene5228	3.212e-64	232.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_2406069_70	351607.Acel_1546	1.004e-89	304.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4ERYG@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_2406069_9	1283283.ATXA01000009_gene3234	7.472e-251	781.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4ERKB@85013|Frankiales	201174|Actinobacteria	E	Belongs to the group II decarboxylase family	gadB	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
MMS3_k127_2406069_101	316274.Haur_3716	3.484e-47	186.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2406069_83	43759.JNWK01000013_gene6439	8.634e-69	241.0	COG4803@1|root,COG4803@2|Bacteria,2IQV0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
MMS3_k127_2406069_5	2074.JNYD01000002_gene5781	6.784e-270	839.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DXJB@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
MMS3_k127_2406069_61	33876.JNXY01000008_gene8389	1.538e-101	342.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4D9ZK@85008|Micromonosporales	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
MMS3_k127_2406069_107	263358.VAB18032_01590	9.992e-41	158.0	COG0009@1|root,COG0009@2|Bacteria,2IM5U@201174|Actinobacteria,4DJSB@85008|Micromonosporales	201174|Actinobacteria	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
MMS3_k127_2406069_81	106370.Francci3_0805	2.492e-71	243.0	COG2514@1|root,COG2514@2|Bacteria,2GUZK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
MMS3_k127_2406069_46	1229780.BN381_250088	1.864e-138	459.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_2406069_64	1120936.KB907220_gene1988	4.151e-98	340.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4EPWP@85012|Streptosporangiales	201174|Actinobacteria	I	Carboxylesterase family	lipM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMS3_k127_2406069_126	358220.C380_19370	9.826e-16	90.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2WEPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMS3_k127_2406069_58	298654.FraEuI1c_1896	2.965e-104	362.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMS3_k127_2406069_77	1122609.AUGT01000009_gene3247	2.439e-75	263.0	COG0411@1|root,COG0411@2|Bacteria,2H5WA@201174|Actinobacteria	201174|Actinobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMS3_k127_2406069_80	1121272.KB903292_gene3945	6.174e-72	253.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D8XW@85008|Micromonosporales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_2406069_1	471852.Tcur_1701	0.0	1154.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4EIDQ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
MMS3_k127_2406069_54	525909.Afer_0306	2.099e-126	419.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CMTW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
MMS3_k127_2406069_20	1121877.JQKF01000016_gene124	6.092e-200	629.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CMRQ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2406069_73	318424.EU78_15170	3.688e-86	297.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,234E2@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
MMS3_k127_2406069_128	562970.Btus_3249	1.653e-10	72.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,4HKBQ@91061|Bacilli,27AE4@186823|Alicyclobacillaceae	91061|Bacilli	T	low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
MMS3_k127_2406069_84	1449069.JMLO01000008_gene3545	7.554e-68	243.0	COG0596@1|root,COG0596@2|Bacteria,2IAVM@201174|Actinobacteria,4G8K9@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
MMS3_k127_2406069_104	1313172.YM304_09550	1.394e-45	172.0	COG1309@1|root,COG1309@2|Bacteria,2HGBF@201174|Actinobacteria,4CNA8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2406069_122	1499967.BAYZ01000074_gene2123	3.167e-19	99.0	COG0438@1|root,COG0438@2|Bacteria,2NQHY@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
MMS3_k127_2406069_34	383372.Rcas_3217	4.283e-171	541.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,375CR@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_2406069_98	1121877.JQKF01000002_gene1731	8.421e-52	193.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4CNHE@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
MMS3_k127_2406069_57	1041522.MCOL_V207910	1.095e-104	347.0	COG0693@1|root,COG0693@2|Bacteria,2GQ3Z@201174|Actinobacteria,235MT@1762|Mycobacteriaceae	201174|Actinobacteria	S	ThiJ/PfpI family-like	-	-	-	-	-	-	-	-	-	-	-	-	ThiJ_like
MMS3_k127_2406069_82	1229780.BN381_310049	1.505e-69	244.0	COG1131@1|root,COG1131@2|Bacteria,2IRXJ@201174|Actinobacteria	201174|Actinobacteria	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
MMS3_k127_2406069_105	1313172.YM304_09610	1.835e-44	170.0	COG2386@1|root,COG2386@2|Bacteria,2HG7F@201174|Actinobacteria,4CN4H@84992|Acidimicrobiia	84992|Acidimicrobiia	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
MMS3_k127_2406069_85	1121877.JQKF01000016_gene155	8.004e-68	250.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria,4CN1E@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
MMS3_k127_2406069_116	525909.Afer_0336	2.421e-27	117.0	COG2332@1|root,COG2332@2|Bacteria,2GZPB@201174|Actinobacteria,4CNCV@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
MMS3_k127_2406069_22	1313172.YM304_09640	4.42e-197	636.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria,4CMX6@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
MMS3_k127_2406069_115	40571.JOEA01000041_gene4666	2.256e-28	121.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4E3DR@85010|Pseudonocardiales	201174|Actinobacteria	CO	Thiol-disulfide isomerase-like thioredoxin	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
MMS3_k127_2406069_127	196162.Noca_1960	8.189e-15	81.0	COG3088@1|root,COG3088@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564	-	ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmH
MMS3_k127_2406069_129	525909.Afer_0339	1.786e-08	66.0	COG3088@1|root,COG3088@2|Bacteria,2GXH0@201174|Actinobacteria,4CNRN@84992|Acidimicrobiia	84992|Acidimicrobiia	P	subunit of a heme lyase	-	-	-	-	-	-	-	-	-	-	-	-	CcmH
MMS3_k127_2406069_65	1229780.BN381_310060	7.373e-98	332.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,3UWEF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
MMS3_k127_2406069_117	1121877.JQKF01000016_gene162	2.64e-25	113.0	COG2345@1|root,COG2345@2|Bacteria,2HGTI@201174|Actinobacteria,4CNV8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_2428170_5	1229780.BN381_100160	6.319e-11	66.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,3UWJE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	ParB-like nuclease domain	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
MMS3_k127_2428170_3	525909.Afer_0032	1.623e-41	168.0	COG3409@1|root,COG3409@2|Bacteria,2HG9Y@201174|Actinobacteria,4CN8M@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Putative peptidoglycan binding domain	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	PG_binding_1
MMS3_k127_2428170_4	525909.Afer_0031	6.297e-41	153.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4CNA4@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
MMS3_k127_2428170_0	1229780.BN381_100158	2.95e-138	448.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,3UWDR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_2428170_2	1313172.YM304_42740	2.008e-55	214.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4CN2K@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
MMS3_k127_2428170_1	1121877.JQKF01000017_gene203	3.397e-80	291.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CN0A@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMS3_k127_2428170_6	1121877.JQKF01000017_gene202	8.224e-11	75.0	2B0G0@1|root,31STG@2|Bacteria,2HGDS@201174|Actinobacteria,4CNCA@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2433491_23	313589.JNB_18343	0.0008112	53.0	2CA6S@1|root,2Z9P6@2|Bacteria,2IAT3@201174|Actinobacteria,4FFFX@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2433491_5	1229780.BN381_170037	4.899e-139	461.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,3UWF2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
MMS3_k127_2433491_4	1229780.BN381_170035	5.881e-144	477.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_2433491_2	1229780.BN381_170034	1.21e-151	496.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,3UWFB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
MMS3_k127_2433491_21	1120948.KB903218_gene2162	2.68e-18	90.0	2A1S7@1|root,30Q0V@2|Bacteria,2GTY5@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293
MMS3_k127_2433491_18	298654.FraEuI1c_0846	5.405e-26	112.0	COG1695@1|root,COG1695@2|Bacteria,2GRVH@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_2433491_22	298654.FraEuI1c_0847	0.0001948	53.0	2AYAU@1|root,31QDD@2|Bacteria,2H5SH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2433491_11	436229.JOEH01000038_gene1691	1.621e-57	207.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,2NMDV@228398|Streptacidiphilus	201174|Actinobacteria	F	Phosphoribosyl transferase domain	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
MMS3_k127_2433491_15	1229780.BN381_170009	5.326e-44	164.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,3UWZ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Ferric uptake regulator family	catR	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMS3_k127_2433491_9	1121877.JQKF01000010_gene733	1.666e-69	244.0	COG1592@1|root,COG1592@2|Bacteria,2HH04@201174|Actinobacteria,4CP0H@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2433491_3	1121877.JQKF01000010_gene732	2.554e-146	475.0	COG0247@1|root,COG0247@2|Bacteria,2HGN8@201174|Actinobacteria,4CNP8@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
MMS3_k127_2433491_13	1229780.BN381_170007	1.148e-46	182.0	COG0247@1|root,COG0247@2|Bacteria,2GVNV@201174|Actinobacteria	201174|Actinobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
MMS3_k127_2433491_20	1313172.YM304_19060	8.19e-20	94.0	2CC1Y@1|root,32YV9@2|Bacteria	2|Bacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
MMS3_k127_2433491_8	1121877.JQKF01000002_gene1746	1.294e-77	282.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CN74@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
MMS3_k127_2433491_1	525909.Afer_1471	9.415e-195	617.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CNGH@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2433491_7	1313172.YM304_19070	2.293e-89	315.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CN1D@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
MMS3_k127_2433491_10	365528.KB891221_gene757	1.908e-60	222.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4ERWS@85013|Frankiales	201174|Actinobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
MMS3_k127_2433491_6	1229780.BN381_10333	1.619e-138	452.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,3UWNW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
MMS3_k127_2433491_19	1116232.AHBF01000040_gene5350	1.009e-24	106.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
MMS3_k127_2433491_14	525909.Afer_1448	5.968e-45	181.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4CN19@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2433491_0	469383.Cwoe_4211	1e-317	981.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
MMS3_k127_2433491_12	525909.Afer_0692	7.847e-52	195.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4CNTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_2433491_17	1229780.BN381_10342	1.349e-29	119.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,3UX04@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Ribosomal L28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
MMS3_k127_2433491_16	1313172.YM304_18510	2.159e-30	126.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CMTA@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
MMS3_k127_24471_5	756067.MicvaDRAFT_2479	8.98e-118	383.0	COG0235@1|root,COG0235@2|Bacteria,1G10W@1117|Cyanobacteria,1H8SZ@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
MMS3_k127_24471_4	1306990.BARG01000047_gene5810	1.305e-137	447.0	COG1960@1|root,COG1960@2|Bacteria,2IBHA@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_24471_0	330084.JNYZ01000004_gene394	3.409e-271	850.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GKFE@201174|Actinobacteria,4DZDF@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bkdA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
MMS3_k127_24471_6	298654.FraEuI1c_5331	7.847e-113	370.0	COG1028@1|root,COG1028@2|Bacteria	298654.FraEuI1c_5331|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_24471_7	298655.KI912266_gene5851	1.085e-94	332.0	COG1028@1|root,COG1028@2|Bacteria,2GNIN@201174|Actinobacteria,4EV3R@85013|Frankiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_24471_8	298655.KI912266_gene5850	1.647e-83	282.0	COG1309@1|root,COG1309@2|Bacteria,2IBE9@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_24471_1	298655.KI912266_gene5843	1.924e-225	708.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_24471_2	298653.Franean1_3692	8.966e-197	622.0	COG2124@1|root,COG2124@2|Bacteria,2GNZS@201174|Actinobacteria,4EUB3@85013|Frankiales	201174|Actinobacteria	Q	PFAM Cytochrome P450	cyp150A5	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_24471_9	1123320.KB889697_gene9027	1.754e-40	155.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_24471_3	1229780.BN381_130390	2.247e-160	517.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1,4.2.1.164	ko:K12452,ko:K13328	ko00520,ko00523,ko01130,map00520,map00523,map01130	M00802	R03391,R03392,R08930	RC00230,RC00704	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_24471_10	1206726.BAFV01000033_gene2338	1.206e-14	83.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria,4FZEY@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2461438_12	1121877.JQKF01000021_gene2202	1.728e-37	147.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMUC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
MMS3_k127_2461438_8	525909.Afer_0380	9.325e-76	274.0	2AMJ0@1|root,31CER@2|Bacteria,2I3ZG@201174|Actinobacteria,4CNHF@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2461438_20	58123.JOFJ01000003_gene2257	8.209e-13	72.0	2EH0W@1|root,33ASY@2|Bacteria,2GSW1@201174|Actinobacteria,4EQEQ@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2461438_4	365528.KB891208_gene3086	6.918e-123	409.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4ETY2@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1589	BATS,Radical_SAM
MMS3_k127_2461438_17	1121933.AUHH01000044_gene3197	6.204e-19	98.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4DUV0@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	hrrA2	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_2461438_18	290397.Adeh_2805	8.833e-18	97.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
MMS3_k127_2461438_16	1380390.JIAT01000010_gene3955	1.422e-23	108.0	COG0681@1|root,COG0681@2|Bacteria,2IDET@201174|Actinobacteria	201174|Actinobacteria	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5305,Peptidase_S24
MMS3_k127_2461438_19	525904.Tter_2030	7.313e-16	91.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF5305,Peptidase_S24
MMS3_k127_2461438_10	1348663.KCH_62540	4.861e-58	212.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,2M0NW@2063|Kitasatospora	201174|Actinobacteria	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
MMS3_k127_2461438_6	247633.GP2143_09295	3.59e-113	381.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,1J6AR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_2461438_5	1123320.KB889562_gene6881	5.761e-117	394.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2461438_3	1120941.AUBL01000001_gene1484	8.553e-133	432.0	COG3392@1|root,COG3392@2|Bacteria,2IBCB@201174|Actinobacteria,4D4T9@85005|Actinomycetales	201174|Actinobacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
MMS3_k127_2461438_2	1449976.KALB_2482	2.285e-169	550.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DYQH@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	stp	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2461438_15	2074.JNYD01000001_gene6030	4.315e-24	119.0	COG1846@1|root,COG1846@2|Bacteria,2HN5D@201174|Actinobacteria,4E5JG@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_2461438_11	1313172.YM304_02800	4.584e-54	198.0	COG1978@1|root,COG1978@2|Bacteria,2GQU6@201174|Actinobacteria	201174|Actinobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1,1.21.4.2	ko:K10672,ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
MMS3_k127_2461438_13	1313172.YM304_02800	9.19e-33	133.0	COG1978@1|root,COG1978@2|Bacteria,2GQU6@201174|Actinobacteria	201174|Actinobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1,1.21.4.2	ko:K10672,ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
MMS3_k127_2461438_21	595460.RRSWK_06191	1.486e-10	65.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS3_k127_2461438_22	748247.AZKH_2300	2.411e-08	63.0	COG2128@1|root,COG2128@2|Bacteria,1RI8R@1224|Proteobacteria,2W5ZT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_2461438_14	67352.JODS01000013_gene5046	2.989e-31	134.0	COG0583@1|root,COG0583@2|Bacteria,2I9HH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_2461438_1	1356854.N007_04550	1.818e-181	587.0	COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,278XK@186823|Alicyclobacillaceae	91061|Bacilli	I	Acyltransferase family	yvhB	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMS3_k127_2461438_7	35754.JNYJ01000001_gene7211	4.312e-97	327.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria,4DABK@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMS3_k127_2461438_0	1449355.JQNR01000005_gene2754	9.969e-182	576.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	adhC	-	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_2491401_3	1229780.BN381_10112	1.934e-66	235.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	rfbC	-	1.1.1.133,4.2.1.46,5.1.3.13	ko:K00067,ko:K01710,ko:K01790	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R02777,R06513,R06514	RC00182,RC00402,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
MMS3_k127_2491401_5	457429.ABJI02000458_gene5437	1.582e-47	185.0	COG1853@1|root,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria	201174|Actinobacteria	K	PFAM flavin reductase domain protein, FMN-binding	-	-	-	ko:K16048	ko00984,ko01100,map00984,map01100	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
MMS3_k127_2491401_2	1313172.YM304_14700	7.271e-69	245.0	COG1235@1|root,COG1235@2|Bacteria,2IJCH@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMS3_k127_2491401_0	471852.Tcur_1579	6.641e-108	358.0	COG0596@1|root,COG0596@2|Bacteria,2HMX1@201174|Actinobacteria,4EHZ7@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	ephC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_2491401_4	1123251.ATWM01000007_gene2403	1.631e-63	229.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4FE8M@85021|Intrasporangiaceae	201174|Actinobacteria	L	Adenine glycosylase	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
MMS3_k127_2491401_1	1313172.YM304_14250	9.349e-86	287.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CMYB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMS3_k127_2612605_13	1121877.JQKF01000002_gene1635	2.715e-66	242.0	2F1PM@1|root,33UPX@2|Bacteria,2H4R3@201174|Actinobacteria,4CN41@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2612605_26	501479.ACNW01000008_gene833	0.0006633	48.0	COG0454@1|root,COG0456@2|Bacteria,1RH0C@1224|Proteobacteria,2U9B4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_2612605_21	1121877.JQKF01000002_gene1631	3.483e-12	73.0	2DDS5@1|root,2ZJ1Y@2|Bacteria,2HDMP@201174|Actinobacteria,4CP3T@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2612605_4	1313172.YM304_25950	4.288e-217	685.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CMUK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
MMS3_k127_2612605_7	1240349.ANGC01000080_gene165	4.895e-143	489.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4FU80@85025|Nocardiaceae	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
MMS3_k127_2612605_14	1121877.JQKF01000002_gene1628	1.516e-59	215.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CN3F@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
MMS3_k127_2612605_23	309801.trd_0809	1.054e-06	56.0	COG1826@1|root,COG1826@2|Bacteria,2G7D4@200795|Chloroflexi,27YMK@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_2612605_3	1313172.YM304_26020	6.774e-226	706.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CMS0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
MMS3_k127_2612605_10	1121877.JQKF01000002_gene1622	3.842e-89	302.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4CMY5@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
MMS3_k127_2612605_9	1121877.JQKF01000002_gene1621	3.308e-96	321.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4CMX8@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
MMS3_k127_2612605_19	1313172.YM304_26060	1.587e-15	78.0	2E9C2@1|root,333JS@2|Bacteria,2HGHP@201174|Actinobacteria,4CNEV@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
MMS3_k127_2612605_6	1313172.YM304_26070	7.679e-183	584.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CMSZ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pup-ligase protein	dop	-	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
MMS3_k127_2612605_1	1229780.BN381_410004	3.388e-250	783.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,3UX32@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Proteasomal ATPase OB/ID domain	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
MMS3_k127_2612605_16	525909.Afer_0906	6.515e-36	138.0	COG1141@1|root,COG1141@2|Bacteria,2IKKX@201174|Actinobacteria,4CN8X@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
MMS3_k127_2612605_11	1229780.BN381_410006	2.535e-84	290.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,3UWFZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
MMS3_k127_2612605_20	525909.Afer_0902	2.46e-15	81.0	28R1E@1|root,2ZDG1@2|Bacteria,2HDQB@201174|Actinobacteria,4CNE2@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
MMS3_k127_2612605_24	1123320.KB889697_gene8849	2.593e-06	55.0	COG2050@1|root,COG2050@2|Bacteria,2IJ8E@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_2612605_2	1229780.BN381_410021	4.272e-236	748.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,3UW9I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Transketolase, pyrimidine binding domain	tkt	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
MMS3_k127_2612605_8	710687.KI912270_gene6186	1.414e-118	399.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,23DAR@1762|Mycobacteriaceae	201174|Actinobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
MMS3_k127_2612605_17	1009370.ALO_10554	5.091e-32	136.0	COG0363@1|root,COG0363@2|Bacteria,1V7VX@1239|Firmicutes,4H4Q4@909932|Negativicutes	909932|Negativicutes	G	6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
MMS3_k127_2612605_0	1123024.AUII01000021_gene79	0.0	1051.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
MMS3_k127_2612605_12	1416752.AYME01000003_gene2554	1.049e-82	309.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4FMB4@85023|Microbacteriaceae	201174|Actinobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMS3_k127_2612605_18	1246995.AFR_04305	2.034e-30	139.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2612605_15	408672.NBCG_05168	1.009e-56	222.0	COG0860@1|root,COG0860@2|Bacteria,2GPA9@201174|Actinobacteria,4DS0S@85009|Propionibacteriales	201174|Actinobacteria	M	Ami_3	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
MMS3_k127_2612605_22	67257.JODR01000013_gene6267	1.27e-11	74.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria	201174|Actinobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
MMS3_k127_2612605_5	1394178.AWOO02000016_gene6866	2.078e-204	648.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EG41@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2633151_6	882082.SaccyDRAFT_2707	3.253e-53	196.0	COG0132@1|root,COG0132@2|Bacteria,2H6DY@201174|Actinobacteria	201174|Actinobacteria	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_26
MMS3_k127_2633151_8	298654.FraEuI1c_0799	3.469e-07	58.0	2DQ34@1|root,334JF@2|Bacteria,2HTM5@201174|Actinobacteria,4ETHK@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2633151_1	222534.KB893670_gene3638	3.445e-124	410.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4ETY2@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1589	BATS,Radical_SAM
MMS3_k127_2633151_0	1078020.KEK_12303	2.39e-194	625.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,238CW@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2633151_5	1160137.KB907307_gene2996	6.853e-56	197.0	COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria,4G2MT@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_2633151_3	1278073.MYSTI_04828	2.902e-84	295.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,438NC@68525|delta/epsilon subdivisions,2X3WD@28221|Deltaproteobacteria,2YXBV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	1.14.13.151,1.14.15.14	ko:K05525,ko:K20497	ko00902,ko01110,map00902,map01110	-	R04366,R09922,R09923,R09924,R09925	RC01137,RC02561,RC02626	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
MMS3_k127_2633151_7	298654.FraEuI1c_5757	7.62e-35	140.0	COG1917@1|root,COG1917@2|Bacteria,2IDTH@201174|Actinobacteria,4EWW4@85013|Frankiales	201174|Actinobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
MMS3_k127_2633151_2	247633.GP2143_09295	3.777e-108	366.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,1J6AR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_2633151_4	649831.L083_6835	1.832e-60	213.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4D924@85008|Micromonosporales	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2750304_6	1463845.JOIG01000009_gene3115	4.863e-159	506.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_2750304_3	1313172.YM304_12700	1.79e-186	606.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CMQA@84992|Acidimicrobiia	84992|Acidimicrobiia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_2750304_17	489825.LYNGBM3L_32980	8.92e-12	73.0	COG1846@1|root,COG1846@2|Bacteria,1G6CB@1117|Cyanobacteria,1HFNP@1150|Oscillatoriales	1117|Cyanobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMS3_k127_2750304_16	4432.XP_010269915.1	1.667e-14	82.0	KOG1940@1|root,KOG1940@2759|Eukaryota,37INM@33090|Viridiplantae,3G8ZR@35493|Streptophyta	35493|Streptophyta	O	finger protein	-	-	-	ko:K16276	-	-	-	-	ko00000,ko04121	-	-	-	Hemerythrin,zf-CHY,zf-RING_2,zinc_ribbon_6
MMS3_k127_2750304_15	65497.JODV01000007_gene504	2.575e-20	94.0	COG0346@1|root,COG0346@2|Bacteria,2GR4M@201174|Actinobacteria,4ECSE@85010|Pseudonocardiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2750304_0	1229780.BN381_450030	1.125e-240	759.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,3UW8G@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMS3_k127_2750304_13	446468.Ndas_3690	4.466e-34	144.0	COG0454@1|root,COG0456@2|Bacteria,2I2QV@201174|Actinobacteria,4EIYD@85012|Streptosporangiales	201174|Actinobacteria	K	FR47-like protein	ats	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_2750304_12	266117.Rxyl_1997	3.49e-41	167.0	COG0454@1|root,COG0456@2|Bacteria,2I4BM@201174|Actinobacteria,4CQBU@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_2750304_10	1229780.BN381_80132	5.962e-72	258.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,3UWGQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
MMS3_k127_2750304_1	351607.Acel_1591	3.771e-225	707.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4ERE0@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
MMS3_k127_2750304_11	525909.Afer_1535	3.853e-45	169.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CN6V@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
MMS3_k127_2750304_7	1121353.H924_05930	6.113e-120	397.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,22KF8@1653|Corynebacteriaceae	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS3_k127_2750304_8	326424.FRAAL5842	1.67e-108	377.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4EX6N@85013|Frankiales	201174|Actinobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_2750304_2	525909.Afer_1538	1.929e-192	621.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CMUV@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMS3_k127_2750304_5	1242864.D187_003824	1.113e-165	539.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,42NBE@68525|delta/epsilon subdivisions,2WMG2@28221|Deltaproteobacteria,2YUJX@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_2750304_14	1313172.YM304_13050	1.123e-25	113.0	2F7CY@1|root,33ZTZ@2|Bacteria,2H76P@201174|Actinobacteria,4CNCM@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2750304_9	1123320.KB889697_gene8851	1.873e-81	285.0	COG0596@1|root,COG0596@2|Bacteria,2GJDM@201174|Actinobacteria	201174|Actinobacteria	CH	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_2750304_4	1121877.JQKF01000003_gene1442	3.001e-178	566.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CNIG@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_2752809_24	298655.KI912267_gene7439	3.717e-38	146.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_2752809_26	96561.Dole_0119	6.691e-29	127.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF3749
MMS3_k127_2752809_17	1150864.MILUP08_42160	1.225e-69	239.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4DE55@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
MMS3_k127_2752809_27	224914.BMEII0574	3.945e-26	121.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria,1J2RD@118882|Brucellaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	idhA	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_2752809_29	1313172.YM304_19200	1.356e-18	96.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	sdaAB	-	2.7.6.5,3.1.7.2,4.3.1.17,4.3.1.19	ko:K01139,ko:K01752,ko:K01754	ko00230,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00336,R00429,R00590,R00996	RC00002,RC00078,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	ACT,HD_4,PALP,RelA_SpoT,SDH_beta
MMS3_k127_2752809_14	1110697.NCAST_34_03470	5.838e-81	288.0	COG1305@1|root,COG1305@2|Bacteria,2GN5D@201174|Actinobacteria,4FYDV@85025|Nocardiaceae	201174|Actinobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
MMS3_k127_2752809_16	1068980.ARVW01000001_gene3319	1.437e-77	274.0	COG2307@1|root,COG2307@2|Bacteria,2GN0T@201174|Actinobacteria,4DZFI@85010|Pseudonocardiales	201174|Actinobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
MMS3_k127_2752809_5	35754.JNYJ01000065_gene5710	5.308e-195	622.0	COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4DARU@85008|Micromonosporales	201174|Actinobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2
MMS3_k127_2752809_11	1121877.JQKF01000035_gene1957	1.5e-130	424.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4CMPJ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMS3_k127_2752809_4	525909.Afer_1881	1.26e-200	631.0	COG0538@1|root,COG0538@2|Bacteria,2IBM8@201174|Actinobacteria,4CNHG@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS3_k127_2752809_15	1313172.YM304_07250	1.389e-80	280.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CN4K@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
MMS3_k127_2752809_23	2002.JOEQ01000005_gene3335	1.917e-39	151.0	COG0662@1|root,COG0662@2|Bacteria,2IPIR@201174|Actinobacteria	201174|Actinobacteria	G	mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K01809,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer
MMS3_k127_2752809_13	525909.Afer_0323	8.295e-93	334.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4CN0K@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMS3_k127_2752809_9	649638.Trad_0076	5.099e-159	519.0	COG0138@1|root,COG0138@2|Bacteria,1WIVC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
MMS3_k127_2752809_21	1229780.BN381_130059	1.685e-53	200.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,3UWRP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
MMS3_k127_2752809_12	1380393.JHVP01000003_gene1104	1.699e-112	381.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	2|Bacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
MMS3_k127_2752809_20	1386969.AWTB01000012_gene3190	3.217e-54	198.0	COG3832@1|root,COG3832@2|Bacteria,2I7GP@201174|Actinobacteria,4GFJB@85026|Gordoniaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_2752809_10	1121877.JQKF01000016_gene138	1.081e-133	433.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CMSK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
MMS3_k127_2752809_8	1313172.YM304_36100	2.361e-161	517.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CMVM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
MMS3_k127_2752809_18	1121877.JQKF01000016_gene136	1.054e-55	200.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4CN3T@84992|Acidimicrobiia	84992|Acidimicrobiia	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
MMS3_k127_2752809_2	1463936.JOJI01000009_gene5305	1.084e-213	692.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria	201174|Actinobacteria	L	DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
MMS3_k127_2752809_1	298653.Franean1_5989	3.863e-225	709.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4ERBR@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
MMS3_k127_2752809_3	1121877.JQKF01000009_gene498	5.566e-205	642.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
MMS3_k127_2752809_30	999611.KI421504_gene386	1.611e-17	91.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2TUWC@28211|Alphaproteobacteria,27ZDM@191028|Leisingera	28211|Alphaproteobacteria	Q	hydratase'	hpaH	-	-	ko:K02509	ko00350,ko01120,map00350,map01120	-	R04132,R06897	RC01615,RC02595	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
MMS3_k127_2752809_25	1229780.BN381_130040	7.866e-38	151.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,3UWZK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_2752809_19	1283283.ATXA01000053_gene4187	9.372e-55	205.0	COG2227@1|root,COG2227@2|Bacteria,2GU8A@201174|Actinobacteria	201174|Actinobacteria	H	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2752809_0	525909.Afer_0444	1.165e-265	827.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CMU0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMS3_k127_2752809_22	525909.Afer_0443	2.731e-43	161.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CN66@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
MMS3_k127_2752809_28	68260.JOAY01000015_gene2684	1.05e-21	101.0	29CFH@1|root,2ZZDX@2|Bacteria,2IN9J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2752809_6	1123073.KB899241_gene1889	1.306e-178	594.0	COG1470@1|root,COG1470@2|Bacteria,1R2J5@1224|Proteobacteria,1T5QX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin	-	-	-	-	-	-	-	-	-	-	-	-	ASH
MMS3_k127_2752809_7	929712.KI912613_gene3286	2.482e-163	529.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CPM9@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha-amylase domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
MMS3_k127_2757612_0	1229780.BN381_150076	2.829e-286	888.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,3UWDQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
MMS3_k127_2757612_2	593907.Celgi_0297	5.476e-103	355.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4F1T5@85016|Cellulomonadaceae	201174|Actinobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
MMS3_k127_2757612_3	369723.Strop_4270	2.23e-98	340.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4D9EZ@85008|Micromonosporales	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
MMS3_k127_2757612_5	1121877.JQKF01000035_gene1966	4.767e-68	239.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CN2D@84992|Acidimicrobiia	84992|Acidimicrobiia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
MMS3_k127_2757612_7	1229780.BN381_150088	2.256e-51	190.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,2II8H@201174|Actinobacteria,3UWMP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
MMS3_k127_2757612_8	1229780.BN381_150088	3.088e-45	173.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,2II8H@201174|Actinobacteria,3UWMP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
MMS3_k127_2757612_6	1229780.BN381_150089	9.236e-66	238.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,3UWDZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
MMS3_k127_2757612_4	472759.Nhal_0362	1.537e-95	331.0	COG2159@1|root,COG2159@2|Bacteria,1QDV1@1224|Proteobacteria,1RYCT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS3_k127_2757612_10	469383.Cwoe_1383	2.587e-41	156.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	-	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
MMS3_k127_2757612_11	1136417.AZWE01000007_gene1892	5.569e-32	143.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4D8RZ@85008|Micromonosporales	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
MMS3_k127_2757612_1	43759.JNWK01000017_gene7582	8.31e-120	406.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria	201174|Actinobacteria	G	synthase	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
MMS3_k127_2757612_9	1229780.BN381_150092	3.19e-44	166.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,3UXD7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferase family 2	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
MMS3_k127_278531_13	1048339.KB913029_gene4057	6.721e-38	151.0	COG1309@1|root,COG1309@2|Bacteria,2GZA7@201174|Actinobacteria,4EWI0@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_278531_3	1108045.GORHZ_154_00380	5.103e-114	389.0	COG2197@1|root,COG2197@2|Bacteria,2I2R1@201174|Actinobacteria,4GDDU@85026|Gordoniaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
MMS3_k127_278531_2	1459636.NTE_02859	9.678e-120	399.0	arCOG01792@1|root,arCOG01792@2157|Archaea	2157|Archaea	K	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
MMS3_k127_278531_1	1123023.JIAI01000013_gene3907	3.449e-120	403.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4E0AI@85010|Pseudonocardiales	201174|Actinobacteria	J	Amidase	bam	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS3_k127_278531_6	367299.JOEE01000003_gene2743	1.598e-86	296.0	COG1122@1|root,COG1122@2|Bacteria,2GMK1@201174|Actinobacteria,4FF62@85021|Intrasporangiaceae	201174|Actinobacteria	P	ABC transporter (Permease)	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF_trnsprt
MMS3_k127_278531_0	1894.JOER01000001_gene5156	1.035e-199	657.0	COG3845@1|root,COG3845@2|Bacteria,2I2Y2@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, ATP-binding protein	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
MMS3_k127_278531_5	1214101.BN159_6066	3.136e-89	313.0	COG0619@1|root,COG0619@2|Bacteria,2GKHK@201174|Actinobacteria	201174|Actinobacteria	P	cobalt transport	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
MMS3_k127_278531_18	500153.JOEK01000004_gene727	6.388e-07	61.0	COG1657@1|root,COG3391@1|root,COG4733@1|root,COG1657@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Cu_amine_oxidN1,NHL,Pkinase,Prenyltrans
MMS3_k127_278531_4	1246995.AFR_04305	2.358e-95	336.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_278531_15	436229.JOEH01000004_gene471	7.695e-17	95.0	COG1657@1|root,COG1657@2|Bacteria,2GIRK@201174|Actinobacteria,2NGSH@228398|Streptacidiphilus	201174|Actinobacteria	I	Squalene-hopene cyclase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
MMS3_k127_278531_12	351607.Acel_0379	5.164e-44	170.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
MMS3_k127_278531_17	290399.Arth_3793	3.242e-08	65.0	2DRM0@1|root,33C8E@2|Bacteria,2GVJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_278531_11	525909.Afer_1161	3.897e-56	213.0	COG0644@1|root,COG0644@2|Bacteria,2GMH9@201174|Actinobacteria,4CNQ0@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
MMS3_k127_278531_7	1121877.JQKF01000012_gene330	8.004e-86	290.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMS3_k127_278531_10	1121877.JQKF01000012_gene331	4.638e-61	220.0	28KBH@1|root,2Z9YH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_278531_19	1463864.JOGO01000031_gene4233	1.885e-05	53.0	COG3832@1|root,COG3832@2|Bacteria,2IHX3@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
MMS3_k127_278531_16	1304865.JAGF01000001_gene1535	2.622e-08	60.0	COG1141@1|root,COG1141@2|Bacteria,2GX0G@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_15
MMS3_k127_278531_9	1246995.AFR_33480	1.302e-77	285.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,4DBY4@85008|Micromonosporales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMS3_k127_278531_14	1304865.JAGF01000001_gene1532	4.237e-34	139.0	COG4097@1|root,COG4097@2|Bacteria	2|Bacteria	P	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Ferric_reduct,NAD_binding_1
MMS3_k127_278531_8	1304865.JAGF01000001_gene1531	2.484e-85	292.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMS3_k127_2788382_14	1193181.BN10_690004	7.733e-86	289.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4FFNS@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2788382_22	298654.FraEuI1c_4419	4.957e-50	190.0	COG2128@1|root,COG2128@2|Bacteria,2IAT6@201174|Actinobacteria	201174|Actinobacteria	K	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_2788382_13	222534.KB893772_gene4676	1.669e-92	315.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4EUUM@85013|Frankiales	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_2788382_11	557599.MKAN_03645	5.816e-125	419.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23D5F@1762|Mycobacteriaceae	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_2788382_7	710686.Mycsm_06053	9.13e-178	565.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23CU1@1762|Mycobacteriaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_2788382_9	1299327.I546_3510	1.254e-130	429.0	COG2124@1|root,COG2124@2|Bacteria,2I2QQ@201174|Actinobacteria,236CF@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2788382_25	113395.AXAI01000023_gene7164	6.184e-36	143.0	2BVCB@1|root,32QSC@2|Bacteria,1RJ2E@1224|Proteobacteria,2UAUU@28211|Alphaproteobacteria,3JZCZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Aromatic acid exporter family member 1	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
MMS3_k127_2788382_23	298654.FraEuI1c_3943	2.167e-47	177.0	COG1309@1|root,COG1309@2|Bacteria,2H4XI@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2788382_6	1370120.AUWR01000009_gene159	1.92e-178	566.0	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria,232IM@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	cyp189A7	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2788382_10	1380356.JNIK01000002_gene4811	7.497e-126	419.0	COG2334@1|root,COG2334@2|Bacteria,2GMC3@201174|Actinobacteria,4EXAJ@85013|Frankiales	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
MMS3_k127_2788382_8	285535.JOEY01000088_gene8929	1.894e-172	562.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2788382_18	298653.Franean1_5230	2.821e-63	229.0	COG1309@1|root,COG1309@2|Bacteria,2II8V@201174|Actinobacteria,4EVIK@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2788382_2	298653.Franean1_0617	4.769e-198	630.0	COG0183@1|root,COG0183@2|Bacteria,2IDC4@201174|Actinobacteria,4EV0I@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2788382_19	298654.FraEuI1c_4445	1.571e-54	195.0	COG1545@1|root,COG1545@2|Bacteria,2IHZR@201174|Actinobacteria,4EVDE@85013|Frankiales	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_2788382_3	365528.KB891137_gene386	8.404e-195	622.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,4EUN0@85013|Frankiales	201174|Actinobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_2788382_17	222534.KB893713_gene2311	2.113e-63	222.0	COG0748@1|root,COG0748@2|Bacteria,2IN9W@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_2788382_4	298654.FraEuI1c_4439	3.049e-189	606.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2788382_12	298653.Franean1_0621	1.96e-114	374.0	COG1028@1|root,COG1028@2|Bacteria,2ICXS@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_2788382_1	298655.KI912266_gene4909	5.98e-229	717.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EU6Y@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2788382_0	298654.FraEuI1c_4443	1.473e-232	730.0	COG1012@1|root,COG1012@2|Bacteria,2IBPD@201174|Actinobacteria,4ETWU@85013|Frankiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
MMS3_k127_2788382_24	1278308.KB907084_gene107	2.478e-36	142.0	COG5646@1|root,COG5646@2|Bacteria,2GPQR@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
MMS3_k127_2788382_20	47839.CCAU010000009_gene1804	5.106e-51	191.0	COG1309@1|root,COG1309@2|Bacteria,2GJZT@201174|Actinobacteria,237ZP@1762|Mycobacteriaceae	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2788382_26	234621.RER_33740	7.39e-05	55.0	28KAT@1|root,2Z9XX@2|Bacteria,2GNVW@201174|Actinobacteria,4FUSP@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2788382_16	1298880.AUEV01000014_gene3704	8.061e-76	267.0	COG4285@1|root,COG4285@2|Bacteria,2GNQ0@201174|Actinobacteria	201174|Actinobacteria	S	Biotin-protein ligase, N terminal	-	-	-	-	-	-	-	-	-	-	-	-	BPL_N
MMS3_k127_2788382_15	1112204.GPOL_c47840	2.29e-83	299.0	COG5361@1|root,COG5361@2|Bacteria,2HES3@201174|Actinobacteria,4GH56@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
MMS3_k127_2788382_21	298654.FraEuI1c_3420	2.258e-50	203.0	COG0683@1|root,COG0683@2|Bacteria,2HZXR@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMS3_k127_2788382_5	298653.Franean1_3190	4.573e-179	576.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
MMS3_k127_2811387_13	1120950.KB892740_gene2582	1.554e-05	50.0	COG0154@1|root,COG0154@2|Bacteria,2GSBS@201174|Actinobacteria,4DU83@85009|Propionibacteriales	201174|Actinobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433,ko:K21801	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_2811387_2	1108045.GORHZ_040_00180	7.589e-91	306.0	COG0426@1|root,COG0426@2|Bacteria,2GJT6@201174|Actinobacteria	201174|Actinobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
MMS3_k127_2811387_7	1108045.GORHZ_040_00170	9.657e-69	238.0	COG3832@1|root,COG3832@2|Bacteria,2I7GP@201174|Actinobacteria,4GFJB@85026|Gordoniaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_2811387_3	1048339.KB913029_gene2134	6.351e-89	298.0	COG1309@1|root,COG1309@2|Bacteria,2IN1Z@201174|Actinobacteria,4EVP6@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2811387_8	1120941.AUBL01000052_gene1018	3.978e-36	144.0	COG0454@1|root,COG0456@2|Bacteria,2IMVD@201174|Actinobacteria,4D5W9@85005|Actinomycetales	201174|Actinobacteria	K	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_2811387_5	1313172.YM304_05030	5.908e-78	282.0	COG1051@1|root,COG1051@2|Bacteria,2HG6C@201174|Actinobacteria,4CN3B@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
MMS3_k127_2811387_12	1313172.YM304_14750	6.379e-06	50.0	2FF8Q@1|root,3476J@2|Bacteria,2H7PN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2811387_11	525909.Afer_1840	4.585e-13	79.0	COG1135@1|root,COG1135@2|Bacteria,2HH1B@201174|Actinobacteria,4CP1I@84992|Acidimicrobiia	84992|Acidimicrobiia	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
MMS3_k127_2811387_6	404589.Anae109_2271	8.084e-72	252.0	COG1606@1|root,COG1606@2|Bacteria,1R7UZ@1224|Proteobacteria,42Q6V@68525|delta/epsilon subdivisions,2WKIM@28221|Deltaproteobacteria,2Z04R@29|Myxococcales	28221|Deltaproteobacteria	S	Asparagine synthase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
MMS3_k127_2811387_4	1229780.BN381_150097	1.195e-78	270.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
MMS3_k127_2811387_0	525909.Afer_1846	1.115e-273	850.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CNG0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMS3_k127_2811387_9	1229780.BN381_150094	1.83e-29	130.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,3UXHU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS3_k127_2811387_1	525909.Afer_1848	7.23e-170	542.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria	201174|Actinobacteria	E	Threonine synthase	thrC3	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_2811387_10	1137271.AZUM01000001_gene1231	1.243e-13	75.0	COG0463@1|root,COG0463@2|Bacteria,2I2NK@201174|Actinobacteria,4E09C@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
MMS3_k127_2833448_2	1123024.AUII01000015_gene3723	5.082e-56	197.0	COG0788@1|root,COG0788@2|Bacteria,2GM0G@201174|Actinobacteria,4E14G@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
MMS3_k127_2833448_1	1229780.BN381_50101	3.877e-91	307.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,3UWE9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Transcriptional regulator	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMS3_k127_2833448_5	1313172.YM304_19860	6.677e-39	155.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CNAX@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
MMS3_k127_2833448_4	1229780.BN381_50109	8.344e-41	163.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,3UWUJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
MMS3_k127_2833448_0	1313172.YM304_19880	1.857e-132	439.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CMVN@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
MMS3_k127_2833448_3	105425.BBPL01000063_gene5255	8.893e-43	175.0	COG1132@1|root,COG1132@2|Bacteria,2GJWP@201174|Actinobacteria,2NECM@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC transporter transmembrane region	ywjA	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_288808_20	1123377.AUIV01000010_gene2186	0.0003638	46.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1X3CH@135614|Xanthomonadales	135614|Xanthomonadales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
MMS3_k127_288808_6	1121877.JQKF01000013_gene259	1.51e-132	430.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CMV6@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Domain of unknown function (DUF4921)	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
MMS3_k127_288808_13	58123.JOFJ01000003_gene2159	7.322e-30	135.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4EGCI@85012|Streptosporangiales	201174|Actinobacteria	G	protein, probably involved in trehalose biosynthesis	treX	-	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
MMS3_k127_288808_0	365528.KB891227_gene309	1.97e-251	790.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4EREC@85013|Frankiales	201174|Actinobacteria	G	Trehalose synthase	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	iNJ661.Rv0126	Alpha-amylase,Malt_amylase_C
MMS3_k127_288808_9	1313172.YM304_10780	4.461e-93	323.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CMYQ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
MMS3_k127_288808_4	1313172.YM304_10760	4.016e-133	437.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CMR2@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
MMS3_k127_288808_5	1313172.YM304_10700	6.316e-133	433.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4CMQH@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
MMS3_k127_288808_17	562970.Btus_3232	6.536e-10	71.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,278JA@186823|Alicyclobacillaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
MMS3_k127_288808_1	525909.Afer_1795	1.364e-243	760.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CMWB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
MMS3_k127_288808_10	1229780.BN381_10048	1.223e-64	231.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,3UWAU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
MMS3_k127_288808_2	1313172.YM304_10640	8.321e-231	725.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CMTI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
MMS3_k127_288808_14	1121933.AUHH01000013_gene600	6.452e-23	110.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,4DRAU@85009|Propionibacteriales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
MMS3_k127_288808_16	1283287.KB822580_gene1701	2.255e-18	92.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4DUHE@85009|Propionibacteriales	201174|Actinobacteria	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
MMS3_k127_288808_15	351607.Acel_0648	4.137e-22	98.0	COG0636@1|root,COG0636@2|Bacteria,2IQZQ@201174|Actinobacteria,4EWJ5@85013|Frankiales	201174|Actinobacteria	C	ATP synthase subunit C	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0015988,GO:0015991,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iNJ661.Rv1305	ATP-synt_C
MMS3_k127_288808_11	1048339.KB913029_gene3391	5.646e-62	224.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4ETD3@85013|Frankiales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
MMS3_k127_288808_19	1123023.JIAI01000013_gene3984	7.705e-05	51.0	29217@1|root,2ZPKF@2|Bacteria,2GPSM@201174|Actinobacteria,4E7U8@85010|Pseudonocardiales	201174|Actinobacteria	S	ATP synthase I	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
MMS3_k127_288808_21	1246484.D479_00410	0.0004874	46.0	COG5336@1|root,COG5336@2|Bacteria,1VF5M@1239|Firmicutes,4HNYV@91061|Bacilli,3NFG1@45667|Halobacillus	91061|Bacilli	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
MMS3_k127_288808_8	1121877.JQKF01000003_gene1529	2.044e-111	372.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CMRB@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase family 4	wecA	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
MMS3_k127_288808_3	1229780.BN381_10027	3.732e-165	535.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,3UWBD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
MMS3_k127_288808_7	1278078.G419_12966	1.274e-118	402.0	COG0183@1|root,COG0183@2|Bacteria,2I3PP@201174|Actinobacteria,4G9JQ@85025|Nocardiaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
MMS3_k127_288808_18	498761.HM1_1085	7.669e-10	71.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
MMS3_k127_288808_12	1229780.BN381_10021	4.139e-30	127.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,3UWRW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
MMS3_k127_2915896_39	1380390.JIAT01000009_gene921	3.126e-06	53.0	COG4705@1|root,COG4705@2|Bacteria,2HWSK@201174|Actinobacteria,4CR06@84995|Rubrobacteria	84995|Rubrobacteria	S	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
MMS3_k127_2915896_14	745310.G432_13960	1.703e-115	380.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2TRJT@28211|Alphaproteobacteria,2K0K2@204457|Sphingomonadales	204457|Sphingomonadales	S	dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
MMS3_k127_2915896_25	1123065.ATWL01000007_gene3162	9.009e-52	186.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
MMS3_k127_2915896_35	1123023.JIAI01000002_gene5010	1.088e-13	83.0	COG0662@1|root,COG0662@2|Bacteria,2IEY6@201174|Actinobacteria,4EBSD@85010|Pseudonocardiales	201174|Actinobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_2915896_28	595536.ADVE02000001_gene770	5.79e-35	138.0	COG0664@1|root,COG0664@2|Bacteria,1RII7@1224|Proteobacteria,2UA8E@28211|Alphaproteobacteria,37072@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
MMS3_k127_2915896_27	1449068.JMLQ01000005_gene3604	7.865e-36	151.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4FTVW@85025|Nocardiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
MMS3_k127_2915896_22	1229780.BN381_70010	1.022e-63	227.0	COG4221@1|root,COG4221@2|Bacteria,2GRRV@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_2915896_3	1283283.ATXA01000009_gene3261	2.961e-183	583.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2915896_24	1207063.P24_08229	4.658e-56	215.0	COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2U6E4@28211|Alphaproteobacteria,2JS0C@204441|Rhodospirillales	204441|Rhodospirillales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS3_k127_2915896_13	164757.Mjls_0307	5.948e-119	398.0	COG1053@1|root,COG1053@2|Bacteria,2GKS3@201174|Actinobacteria,233WX@1762|Mycobacteriaceae	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	-	-	1.3.99.5	ko:K16051	ko00984,ko01120,map00984,map01120	-	R01834	RC00145	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
MMS3_k127_2915896_23	1123320.KB889664_gene1212	1.163e-58	212.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
MMS3_k127_2915896_26	105420.BBPO01000118_gene4260	2.16e-49	181.0	COG2764@1|root,COG2764@2|Bacteria,2I2KY@201174|Actinobacteria,2NIS5@228398|Streptacidiphilus	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_2915896_18	1133849.O3I_013415	2.735e-72	246.0	COG3832@1|root,COG3832@2|Bacteria,2I45V@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_2915896_17	994479.GL877878_gene804	1.004e-89	310.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4DZ5Z@85010|Pseudonocardiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
MMS3_k127_2915896_7	298653.Franean1_5645	5.127e-144	461.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4ESZE@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2915896_4	590998.Celf_0800	1.936e-167	542.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4F21C@85016|Cellulomonadaceae	201174|Actinobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
MMS3_k127_2915896_16	882082.SaccyDRAFT_4608	7.567e-95	319.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DXSI@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase LigD, polymerase	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
MMS3_k127_2915896_10	1380390.JIAT01000010_gene4509	2.794e-130	439.0	COG0473@1|root,COG0473@2|Bacteria,2I4BP@201174|Actinobacteria,4CPAZ@84995|Rubrobacteria	84995|Rubrobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
MMS3_k127_2915896_34	391038.Bphy_2363	2.374e-15	89.0	COG0477@1|root,COG2814@2|Bacteria,1MWKH@1224|Proteobacteria,2VH75@28216|Betaproteobacteria,1JZTM@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_2915896_20	68570.DC74_1782	1.2e-70	252.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
MMS3_k127_2915896_33	543632.JOJL01000027_gene2899	1.7e-18	93.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria,4DFTJ@85008|Micromonosporales	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
MMS3_k127_2915896_6	35754.JNYJ01000042_gene1373	3.622e-163	525.0	COG3259@1|root,COG3259@2|Bacteria,2GQ33@201174|Actinobacteria,4DABR@85008|Micromonosporales	201174|Actinobacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
MMS3_k127_2915896_15	1304865.JAGF01000001_gene2441	5.697e-101	338.0	COG1941@1|root,COG1941@2|Bacteria,2GSPN@201174|Actinobacteria	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
MMS3_k127_2915896_19	1172179.AUKV01000023_gene2065	5.392e-72	258.0	COG0543@1|root,COG0543@2|Bacteria,2HXFY@201174|Actinobacteria	201174|Actinobacteria	CH	Oxidoreductase	asrB	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
MMS3_k127_2915896_29	518766.Rmar_2587	3.83e-31	132.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
MMS3_k127_2915896_9	351607.Acel_1015	1.498e-131	430.0	COG0247@1|root,COG0247@2|Bacteria,2I3IR@201174|Actinobacteria,4EUJ2@85013|Frankiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
MMS3_k127_2915896_11	1229780.BN381_80401	3.324e-125	410.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,3UW79@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
MMS3_k127_2915896_21	864051.BurJ1DRAFT_4544	2.209e-64	233.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2VQ8C@28216|Betaproteobacteria,1KKPN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.1.58,1.2.7.1	ko:K00172,ko:K18357	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
MMS3_k127_2915896_2	345341.KUTG_00477	5.293e-187	594.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
MMS3_k127_2915896_5	1440774.Y900_027890	1.051e-164	524.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_2915896_1	1116232.AHBF01000151_gene1189	4.037e-244	775.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria	201174|Actinobacteria	E	Glutamate synthase	preT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
MMS3_k127_2915896_0	448385.sce4570	2.625e-294	923.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria,2YW7G@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2101	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS3_k127_2915896_12	1380370.JIBA01000019_gene1091	3.519e-123	433.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,4FFB5@85021|Intrasporangiaceae	201174|Actinobacteria	C	4-hydroxybutyrate CoA-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
MMS3_k127_2915896_38	1122612.AUBA01000011_gene825	1.873e-09	69.0	2AJXF@1|root,31AKH@2|Bacteria,1Q5TH@1224|Proteobacteria,2VC40@28211|Alphaproteobacteria,2KBZF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2915896_36	926569.ANT_05420	1.791e-13	83.0	COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_2915896_32	749414.SBI_04955	3.509e-25	122.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMS3_k127_2915896_8	525909.Afer_1575	1.212e-136	445.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter substrate-binding protein	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
MMS3_k127_2915896_30	543632.JOJL01000039_gene1653	1.931e-30	128.0	COG1520@1|root,COG5297@1|root,COG1520@2|Bacteria,COG5297@2|Bacteria,2I9FJ@201174|Actinobacteria	201174|Actinobacteria	M	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
MMS3_k127_2937490_24	1313172.YM304_37870	2.341e-27	116.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria	201174|Actinobacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
MMS3_k127_2937490_14	1229780.BN381_60047	9.853e-62	227.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,3UWS1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
MMS3_k127_2937490_25	1313172.YM304_37890	1.14e-25	112.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
MMS3_k127_2937490_4	1313172.YM304_37900	1.705e-120	400.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4CMYV@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2937490_18	1229780.BN381_60050	4.941e-41	159.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,3UXII@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMS3_k127_2937490_8	656024.FsymDg_2119	3.572e-98	328.0	COG0605@1|root,COG0605@2|Bacteria,2GJV8@201174|Actinobacteria,4EUBT@85013|Frankiales	201174|Actinobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
MMS3_k127_2937490_28	1068978.AMETH_4598	0.0001408	50.0	COG1734@1|root,COG1734@2|Bacteria,2I16A@201174|Actinobacteria,4E6FX@85010|Pseudonocardiales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
MMS3_k127_2937490_0	1211815.CBYP010000062_gene3188	0.0	1140.0	COG0657@1|root,COG2072@1|root,COG0657@2|Bacteria,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria	201174|Actinobacteria	P	Flavoprotein involved in K transport	pamO	-	1.14.13.92	ko:K18229	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3,FMO-like,Pyr_redox_2,Pyr_redox_3
MMS3_k127_2937490_6	1146883.BLASA_3968	1.491e-114	388.0	COG0520@1|root,COG0520@2|Bacteria,2GMIC@201174|Actinobacteria,4EUQQ@85013|Frankiales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_2937490_21	298653.Franean1_4419	2.01e-33	142.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
MMS3_k127_2937490_11	1003195.SCAT_0864	4.448e-78	274.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria	201174|Actinobacteria	C	Citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
MMS3_k127_2937490_2	1137269.AZWL01000003_gene1384	1.508e-151	494.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_2937490_15	446470.Snas_5222	4.021e-52	190.0	2DMC7@1|root,32J0V@2|Bacteria,2I81N@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
MMS3_k127_2937490_1	1313172.YM304_35030	8.343e-157	502.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4CNIH@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_2937490_12	1048834.TC41_0467	4.693e-78	280.0	COG1686@1|root,COG1686@2|Bacteria,1VZJP@1239|Firmicutes	1239|Firmicutes	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
MMS3_k127_2937490_26	1380356.JNIK01000015_gene2361	2.359e-15	87.0	COG5416@1|root,COG5416@2|Bacteria,2HD5K@201174|Actinobacteria	201174|Actinobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
MMS3_k127_2937490_17	1121877.JQKF01000023_gene2242	1.122e-47	179.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4CN1Q@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMS3_k127_2937490_19	1313172.YM304_09020	2.245e-38	149.0	COG0314@1|root,COG0314@2|Bacteria,2HG21@201174|Actinobacteria,4CN80@84992|Acidimicrobiia	84992|Acidimicrobiia	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
MMS3_k127_2937490_9	1313172.YM304_11030	5.381e-98	336.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4CMP8@84992|Acidimicrobiia	84992|Acidimicrobiia	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
MMS3_k127_2937490_10	644966.Tmar_1413	9.3e-97	327.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WCYS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
MMS3_k127_2937490_27	1229780.BN381_60052	5.392e-15	77.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
MMS3_k127_2937490_22	1121877.JQKF01000003_gene1581	4.063e-30	126.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CMYS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
MMS3_k127_2937490_7	1894.JOER01000012_gene1882	3.396e-107	360.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	modC	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
MMS3_k127_2937490_13	463191.SSEG_09046	2.026e-68	243.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria	201174|Actinobacteria	P	Molybdate ABC transporter	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
MMS3_k127_2937490_16	105420.BBPO01000020_gene5580	5.826e-51	192.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,2NG9Z@228398|Streptacidiphilus	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
MMS3_k127_2937490_20	1048339.KB913029_gene4147	6.899e-35	137.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4ET46@85013|Frankiales	201174|Actinobacteria	H	DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
MMS3_k127_2937490_3	298653.Franean1_3258	3.558e-130	424.0	COG1028@1|root,COG1028@2|Bacteria,2GJ9X@201174|Actinobacteria,4EUC4@85013|Frankiales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_2937490_23	266117.Rxyl_0118	5.742e-29	129.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4CQMI@84995|Rubrobacteria	84995|Rubrobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
MMS3_k127_2937490_5	1306174.JODP01000006_gene3139	3.022e-119	395.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
MMS3_k127_2970572_9	313589.JNB_18343	2.524e-07	64.0	2CA6S@1|root,2Z9P6@2|Bacteria,2IAT3@201174|Actinobacteria,4FFFX@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2970572_8	1123073.KB899242_gene1494	6.102e-11	76.0	COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,1QVSF@1224|Proteobacteria,1SGFH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
MMS3_k127_2970572_10	1123269.NX02_25980	0.0006847	51.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U8U8@28211|Alphaproteobacteria,2KCU8@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
MMS3_k127_2970572_3	35754.JNYJ01000035_gene3877	2.65e-102	348.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4D93E@85008|Micromonosporales	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208,ko:K11611	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_2970572_5	1229780.BN381_50168	6.118e-59	217.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria	201174|Actinobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	npdG	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
MMS3_k127_2970572_1	1229780.BN381_50169	3.195e-164	524.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,3UX20@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
MMS3_k127_2970572_0	298655.KI912267_gene7487	2.502e-243	769.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4ES1K@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
MMS3_k127_2970572_6	1313172.YM304_19730	2.979e-50	186.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4CN4U@84992|Acidimicrobiia	84992|Acidimicrobiia	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
MMS3_k127_2970572_7	1121877.JQKF01000039_gene1859	3.34e-31	138.0	COG0392@1|root,COG0392@2|Bacteria,2HGNQ@201174|Actinobacteria,4CNQG@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMS3_k127_2970572_2	479432.Sros_6127	6.362e-156	517.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4EFYE@85012|Streptosporangiales	201174|Actinobacteria	J	Elongation factor G, domain IV	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_2970572_4	1121946.AUAX01000029_gene1996	7.297e-62	225.0	COG0463@1|root,COG2244@1|root,COG0463@2|Bacteria,COG2244@2|Bacteria,2I7M5@201174|Actinobacteria,4DFBM@85008|Micromonosporales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Polysacc_synt_3
MMS3_k127_297894_19	675635.Psed_3329	1.165e-34	133.0	COG3651@1|root,COG3651@2|Bacteria,2IHNI@201174|Actinobacteria,4E64C@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
MMS3_k127_297894_16	710685.MycrhN_0388	3.675e-41	161.0	COG3832@1|root,COG3832@2|Bacteria,2IFJT@201174|Actinobacteria,238NR@1762|Mycobacteriaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_297894_7	1313172.YM304_12820	1.033e-127	427.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CMU6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_297894_10	1123258.AQXZ01000004_gene7	6.663e-99	329.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4FW50@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
MMS3_k127_297894_2	483219.LILAB_30635	2.033e-155	507.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,437GH@68525|delta/epsilon subdivisions,2X2P4@28221|Deltaproteobacteria,2YU9N@29|Myxococcales	28221|Deltaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
MMS3_k127_297894_20	2002.JOEQ01000017_gene7764	1.133e-28	129.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria,4EI9B@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
MMS3_k127_297894_15	1122611.KB904018_gene7100	2.856e-45	178.0	COG0842@1|root,COG0842@2|Bacteria,2I0XU@201174|Actinobacteria,4EGKP@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_297894_0	977880.RALTA_A3198	1.094e-163	531.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2VMQV@28216|Betaproteobacteria,1K01B@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
MMS3_k127_297894_6	1206733.BAGC01000035_gene3639	4.969e-132	428.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4FYMF@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_297894_5	557599.MKAN_07645	8.522e-137	449.0	COG2124@1|root,COG2124@2|Bacteria,2GKKN@201174|Actinobacteria,23477@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.15.13	ko:K17474	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
MMS3_k127_297894_11	1121877.JQKF01000003_gene1583	1.444e-71	254.0	COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
MMS3_k127_297894_3	1313172.YM304_25510	3.46e-153	493.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4CNFE@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_297894_13	1449048.JQKU01000022_gene2745	2.502e-52	201.0	COG0596@1|root,COG0596@2|Bacteria,2I9EI@201174|Actinobacteria,23667@1762|Mycobacteriaceae	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_297894_1	1172179.AUKV01000037_gene8278	1.736e-155	505.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_297894_14	105420.BBPO01000056_gene3451	4.345e-48	194.0	2D9QC@1|root,32TTR@2|Bacteria,2IK1S@201174|Actinobacteria,2NG5Q@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_297894_22	40571.JOEA01000009_gene3354	6.446e-26	116.0	290Z6@1|root,2ZNKX@2|Bacteria,2I9VD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_297894_18	525904.Tter_1310	4.867e-36	143.0	COG0288@1|root,COG0288@2|Bacteria,2NR8X@2323|unclassified Bacteria	2|Bacteria	H	Reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
MMS3_k127_297894_4	298654.FraEuI1c_6659	1.882e-143	463.0	COG3804@1|root,COG3804@2|Bacteria,2I8CX@201174|Actinobacteria	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	-	-	-	-	-	-	-	-	-	-	DapB_N
MMS3_k127_297894_17	1123258.AQXZ01000017_gene3856	3.455e-39	169.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4FY5F@85025|Nocardiaceae	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS3_k127_297894_21	196367.JNFG01000013_gene5155	8.346e-28	132.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VHM7@28216|Betaproteobacteria,1K24P@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS3_k127_297894_9	1280954.HPO_16033	2.787e-100	336.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TQUY@28211|Alphaproteobacteria,440PV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_297894_8	298655.KI912266_gene4972	1.348e-115	389.0	28JDP@1|root,2Z97Z@2|Bacteria,2I9EC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_297894_12	469371.Tbis_0837	2.657e-55	214.0	COG1544@1|root,COG1544@2|Bacteria,2IB6N@201174|Actinobacteria,4E3BW@85010|Pseudonocardiales	201174|Actinobacteria	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
MMS3_k127_297894_23	479434.Sthe_1024	9.747e-12	68.0	COG1503@1|root,COG1503@2|Bacteria,2G745@200795|Chloroflexi,27XGI@189775|Thermomicrobia	189775|Thermomicrobia	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_2
MMS3_k127_3014087_18	1416752.AYME01000003_gene2368	4.052e-09	59.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4FN6Q@85023|Microbacteriaceae	201174|Actinobacteria	H	Biotin protein ligase C terminal domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
MMS3_k127_3014087_2	211114.JOEF01000001_gene7249	3.782e-154	496.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4E22V@85010|Pseudonocardiales	201174|Actinobacteria	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_3014087_11	1229780.BN381_10136	7.238e-76	264.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,3UWQ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
MMS3_k127_3014087_3	1229780.BN381_10176	1.57e-140	462.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,3UW6R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_3014087_4	1214101.BN159_0692	7.068e-119	403.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria	201174|Actinobacteria	GM	epimerase dehydratase	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
MMS3_k127_3014087_10	1382356.JQMP01000004_gene670	7.205e-76	278.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3014087_15	743718.Isova_2395	1.071e-49	188.0	COG1216@1|root,COG1216@2|Bacteria,2I5Z7@201174|Actinobacteria,4F4YX@85017|Promicromonosporaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.289	ko:K16870	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_2
MMS3_k127_3014087_20	1123267.JONN01000001_gene1429	5.264e-05	55.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U9RE@28211|Alphaproteobacteria,2K4GD@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
MMS3_k127_3014087_7	1299327.I546_3407	1.308e-93	316.0	COG1028@1|root,COG1028@2|Bacteria,2GM3I@201174|Actinobacteria,2368D@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3014087_12	1205680.CAKO01000035_gene257	9.979e-76	268.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TV8M@28211|Alphaproteobacteria,2JXBR@204441|Rhodospirillales	204441|Rhodospirillales	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3014087_8	1229780.BN381_300033	1.193e-83	297.0	COG0604@1|root,COG0604@2|Bacteria,2HFQJ@201174|Actinobacteria,3UXC1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3014087_17	1380370.JIBA01000012_gene3837	7.404e-30	136.0	COG0454@1|root,COG1708@1|root,COG0456@2|Bacteria,COG1708@2|Bacteria,2II3I@201174|Actinobacteria,4FK28@85021|Intrasporangiaceae	201174|Actinobacteria	K	Domain of unknown function (DUF4111)	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
MMS3_k127_3014087_9	926550.CLDAP_19010	1.744e-77	264.0	COG2818@1|root,COG2818@2|Bacteria,2G78E@200795|Chloroflexi	200795|Chloroflexi	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
MMS3_k127_3014087_14	1532557.JL37_10230	5.613e-56	201.0	COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2VQS6@28216|Betaproteobacteria,3T45Y@506|Alcaligenaceae	28216|Betaproteobacteria	J	family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_3014087_1	1122247.C731_0728	1.496e-198	634.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,232FY@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD19_2	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3014087_0	68170.KL590496_gene9347	6.481e-223	699.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DZU8@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	aldC	-	1.2.1.3,1.2.1.39,1.2.1.8	ko:K00128,ko:K00130,ko:K00146	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_3014087_5	1380347.JNII01000005_gene3240	6.139e-117	382.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4EUFY@85013|Frankiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3014087_16	1185876.BN8_04987	4.028e-32	143.0	COG1209@1|root,COG1209@2|Bacteria,4NF32@976|Bacteroidetes,47K6F@768503|Cytophagia	976|Bacteroidetes	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
MMS3_k127_3014087_6	525909.Afer_1086	1.042e-115	384.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4CMQV@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
MMS3_k127_3014087_13	1121422.AUMW01000014_gene1315	4.962e-63	231.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24FFI@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_3014087_19	479432.Sros_0086	1.929e-05	51.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3017947_4	298655.KI912266_gene2743	3.45e-90	308.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,2GP7R@201174|Actinobacteria,4EUK7@85013|Frankiales	201174|Actinobacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
MMS3_k127_3017947_0	298654.FraEuI1c_3295	7.564e-236	745.0	COG0146@1|root,COG0146@2|Bacteria,2IA3H@201174|Actinobacteria	201174|Actinobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_3017947_7	1449357.JQLK01000001_gene2041	1.537e-54	199.0	COG0500@1|root,COG2226@2|Bacteria,1WKP7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_3017947_6	35754.JNYJ01000030_gene7721	8.321e-56	216.0	COG1946@1|root,COG1946@2|Bacteria,2GMZB@201174|Actinobacteria,4DDWM@85008|Micromonosporales	201174|Actinobacteria	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
MMS3_k127_3017947_9	390989.JOEG01000020_gene2778	7.288e-25	114.0	COG3153@1|root,COG3153@2|Bacteria,2I3ZS@201174|Actinobacteria,4DB6D@85008|Micromonosporales	201174|Actinobacteria	S	Gcn5-related n-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_3017947_3	357808.RoseRS_3616	1.593e-120	416.0	COG3525@1|root,COG3525@2|Bacteria,2G609@200795|Chloroflexi,376QW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
MMS3_k127_3017947_8	298654.FraEuI1c_4087	1.067e-39	158.0	2CIS7@1|root,2ZU2U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3017947_2	33876.JNXY01000037_gene7990	3.411e-122	414.0	2CE4Q@1|root,2Z7WX@2|Bacteria,2H0P6@201174|Actinobacteria,4DDZ8@85008|Micromonosporales	201174|Actinobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
MMS3_k127_3017947_1	235985.BBPN01000040_gene354	1.588e-179	579.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
MMS3_k127_3017947_5	1280946.HY29_05760	1.607e-72	259.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,43X1D@69657|Hyphomonadaceae	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3021840_34	1341181.FLJC2902T_21090	1.615e-31	144.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4P772@976|Bacteroidetes,1IBXR@117743|Flavobacteriia,2NWQB@237|Flavobacterium	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SprB
MMS3_k127_3021840_38	1313172.YM304_04340	3.314e-19	100.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
MMS3_k127_3021840_22	1089544.KB912942_gene2779	3.896e-75	262.0	COG0500@1|root,COG2226@2|Bacteria,2I3BB@201174|Actinobacteria,4E2F9@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_3021840_2	298655.KI912266_gene3743	1.72e-217	687.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	ltp1_1	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_3021840_28	710687.KI912270_gene648	2.729e-58	205.0	COG1545@1|root,COG1545@2|Bacteria,2IH6P@201174|Actinobacteria,23998@1762|Mycobacteriaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_3021840_24	298654.FraEuI1c_1436	1.131e-74	256.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4EVR3@85013|Frankiales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_3021840_33	365528.KB891261_gene457	7.44e-34	136.0	COG0642@1|root,COG0642@2|Bacteria,2I436@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_3021840_8	1463887.KL589977_gene8245	5.271e-158	503.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_3021840_4	710111.FraQA3DRAFT_3542	3.64e-187	609.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_3021840_40	330084.JNYZ01000023_gene3575	1.691e-08	63.0	COG2314@1|root,COG2314@2|Bacteria,2GSEK@201174|Actinobacteria,4E6FR@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
MMS3_k127_3021840_39	1122611.KB903964_gene4965	1.867e-12	73.0	COG1983@1|root,COG1983@2|Bacteria,2GWIA@201174|Actinobacteria,4EKDA@85012|Streptosporangiales	201174|Actinobacteria	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
MMS3_k127_3021840_21	1114959.SZMC14600_18344	4.704e-77	283.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DXQC@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
MMS3_k127_3021840_20	1033730.CAHG01000003_gene91	9.248e-81	295.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4DQ1R@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_3021840_23	1150599.MPHLEI_11275	7.186e-75	260.0	COG1218@1|root,COG1218@2|Bacteria,2GMW7@201174|Actinobacteria,233VA@1762|Mycobacteriaceae	201174|Actinobacteria	P	PFAM inositol monophosphatase	cysQ_1	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
MMS3_k127_3021840_36	479433.Caci_1900	4.171e-27	115.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria	201174|Actinobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_3021840_7	1068980.ARVW01000001_gene422	1.92e-158	514.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria,4DX5S@85010|Pseudonocardiales	201174|Actinobacteria	Q	Retinal pigment epithelial membrane protein	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
MMS3_k127_3021840_13	1229780.BN381_100028	2.386e-106	357.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
MMS3_k127_3021840_10	1211815.CBYP010000067_gene109	1.246e-131	426.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
MMS3_k127_3021840_6	1282876.BAOK01000001_gene3035	7.793e-169	553.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,4BPZN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3021840_37	1382306.JNIM01000001_gene1424	1.596e-24	119.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_3021840_11	1078020.KEK_09197	1.826e-129	434.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,237UH@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
MMS3_k127_3021840_5	1313172.YM304_00280	4.114e-171	549.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3021840_29	392499.Swit_3641	3.879e-44	178.0	COG5361@1|root,COG5361@2|Bacteria,1PF7H@1224|Proteobacteria,2U4QR@28211|Alphaproteobacteria,2K2I1@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
MMS3_k127_3021840_19	876044.IMCC3088_1495	5.505e-83	290.0	2DBBP@1|root,2Z88Z@2|Bacteria,1R3B4@1224|Proteobacteria,1RSHG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
MMS3_k127_3021840_18	591167.Sfla_5254	8.641e-90	316.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipP	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_3021840_30	479433.Caci_7509	5.023e-44	174.0	2DPKA@1|root,332H3@2|Bacteria,2I2YH@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
MMS3_k127_3021840_12	1348663.KCH_57270	1.124e-125	420.0	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria,2M1BB@2063|Kitasatospora	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
MMS3_k127_3021840_3	1120936.KB907219_gene3188	1.208e-202	650.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4EG37@85012|Streptosporangiales	201174|Actinobacteria	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMS3_k127_3021840_14	1380386.JIAW01000027_gene7119	1.512e-101	355.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,237RH@1762|Mycobacteriaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_3021840_31	1206726.BAFV01000025_gene1832	7.762e-40	168.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4G0P0@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_3021840_26	1313172.YM304_21260	3.484e-69	254.0	COG0583@1|root,COG0583@2|Bacteria,2HF8Y@201174|Actinobacteria,4CN2C@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
MMS3_k127_3021840_9	1385519.N801_16105	2.262e-132	437.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4FF65@85021|Intrasporangiaceae	201174|Actinobacteria	EI	Phospholipid biosynthesis protein	-	-	2.3.1.51,3.1.3.3	ko:K15781	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,HAD
MMS3_k127_3021840_15	351607.Acel_1706	1.616e-99	339.0	COG0770@1|root,COG0770@2|Bacteria,2I2EU@201174|Actinobacteria	201174|Actinobacteria	M	Mur ligase, middle domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
MMS3_k127_3021840_27	1122611.KB903970_gene2604	2.921e-62	231.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4EGIA@85012|Streptosporangiales	201174|Actinobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
MMS3_k127_3021840_17	1440774.Y900_022215	1.448e-93	317.0	COG1234@1|root,COG1234@2|Bacteria,2HV83@201174|Actinobacteria,232BJ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
MMS3_k127_3021840_35	1168065.DOK_07214	4.907e-30	129.0	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,1SAVX@1236|Gammaproteobacteria,1JB9W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
MMS3_k127_3021840_25	1313172.YM304_22230	8.05e-70	256.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria,4CN1J@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
MMS3_k127_3021840_1	525909.Afer_1430	1.031e-246	774.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria,4CMV3@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
MMS3_k127_3021840_16	298655.KI912266_gene3537	2.143e-96	330.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,4EWHX@85013|Frankiales	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3021840_0	1313172.YM304_22260	9.549e-275	865.0	COG0560@1|root,COG3320@1|root,COG0560@2|Bacteria,COG3320@2|Bacteria,2GJVX@201174|Actinobacteria,4CMQQ@84992|Acidimicrobiia	84992|Acidimicrobiia	EQ	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4
MMS3_k127_3021840_32	1313172.YM304_22270	1.255e-36	146.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
MMS3_k127_3104104_4	405948.SACE_7046	2.067e-09	70.0	COG3118@1|root,COG3118@2|Bacteria,2I35R@201174|Actinobacteria	201174|Actinobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
MMS3_k127_3104104_2	1246995.AFR_04305	1.343e-91	320.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3104104_0	656024.FsymDg_0877	1.032e-109	361.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4ERJD@85013|Frankiales	201174|Actinobacteria	C	PFAM Luciferase-like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3104104_3	35754.JNYJ01000001_gene7243	1.359e-25	108.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria,4DJZN@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3104104_1	1463857.JOFZ01000007_gene265	1.531e-105	348.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria	201174|Actinobacteria	Q	Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS3_k127_3136218_10	525909.Afer_0722	4.199e-06	50.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,4CNRB@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
MMS3_k127_3136218_6	526225.Gobs_3234	1.488e-34	145.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,4EV9F@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_3136218_1	525909.Afer_0728	8.732e-178	571.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CMRS@84992|Acidimicrobiia	84992|Acidimicrobiia	HP	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
MMS3_k127_3136218_5	1123320.KB889668_gene3364	1.614e-40	161.0	COG2267@1|root,COG2267@2|Bacteria,2I7DU@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_3136218_2	1229780.BN381_30041	5.441e-131	431.0	COG0667@1|root,COG0667@2|Bacteria,2HFWW@201174|Actinobacteria,3UXJ2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_3136218_3	351607.Acel_1987	5.321e-54	201.0	COG3336@1|root,COG3336@2|Bacteria,2IKZR@201174|Actinobacteria,4EX8B@85013|Frankiales	201174|Actinobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG
MMS3_k127_3136218_8	1123320.KB889562_gene6840	2.369e-31	130.0	COG0346@1|root,COG0346@2|Bacteria,2GW7J@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
MMS3_k127_3136218_0	1313172.YM304_28970	8.595e-234	736.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CMX5@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
MMS3_k127_3136218_7	110319.CF8_3025	5.441e-33	135.0	COG2329@1|root,COG2329@2|Bacteria,2IQWX@201174|Actinobacteria,4DVZ1@85009|Propionibacteriales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
MMS3_k127_3136218_9	1278078.G419_25177	3.577e-25	107.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria,4FVE2@85025|Nocardiaceae	201174|Actinobacteria	S	Peptidase dimerisation domain	amiB1	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_315867_6	297246.lpp0865	1.65e-86	306.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RN7X@1236|Gammaproteobacteria,1JCZW@118969|Legionellales	118969|Legionellales	I	Acyl-CoA dehydrogenase, middle domain	aidB	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
MMS3_k127_315867_2	1283283.ATXA01000008_gene3182	6.364e-126	408.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4EU1X@85013|Frankiales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
MMS3_k127_315867_0	1386089.N865_07540	0.0	1297.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4FIMQ@85021|Intrasporangiaceae	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
MMS3_k127_315867_10	1340493.JNIF01000002_gene1262	1.713e-05	59.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
MMS3_k127_315867_3	1194972.MVAC_07441	5.838e-119	397.0	COG2141@1|root,COG2141@2|Bacteria,2GKPX@201174|Actinobacteria,2335G@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_315867_8	1078020.KEK_14668	1.921e-31	127.0	2ECT0@1|root,336QK@2|Bacteria,2IKM4@201174|Actinobacteria,23E53@1762|Mycobacteriaceae	1078020.KEK_14668|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_315867_1	1078020.KEK_17283	1.161e-176	571.0	COG0318@1|root,COG0318@2|Bacteria,2GJYP@201174|Actinobacteria,23D91@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_315867_9	1386089.N865_14150	3.195e-23	109.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4FI5A@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
MMS3_k127_315867_7	1463917.JODC01000042_gene2575	3.783e-48	184.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_315867_4	1125971.ASJB01000099_gene2288	7.213e-100	343.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria,4E1YQ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_315867_5	1030157.AFMP01000026_gene1009	6.204e-90	308.0	28JDP@1|root,2Z97Z@2|Bacteria,1R6U7@1224|Proteobacteria,2UIH3@28211|Alphaproteobacteria,2K72A@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_336133_16	105422.BBPM01000085_gene7389	3.575e-40	154.0	COG1309@1|root,COG1309@2|Bacteria,2HD07@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_336133_6	1206743.BAGM01000199_gene987	7.758e-103	344.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4FXF4@85025|Nocardiaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_336133_10	1206743.BAGM01000199_gene988	4.489e-79	273.0	COG1277@1|root,COG1277@2|Bacteria,2ID14@201174|Actinobacteria,4G3H5@85025|Nocardiaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_336133_0	222534.KB893783_gene5236	0.0	1353.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4ERXD@85013|Frankiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMS3_k127_336133_2	1229780.BN381_420007	2.838e-269	861.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,3UWC3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
MMS3_k127_336133_15	287986.DV20_14180	1.407e-44	176.0	COG0237@1|root,COG2320@1|root,COG0237@2|Bacteria,COG2320@2|Bacteria,2GN96@201174|Actinobacteria,4DYSR@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
MMS3_k127_336133_19	330214.NIDE3021	1.467e-14	84.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
MMS3_k127_336133_1	656024.FsymDg_2137	7.128e-288	943.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
MMS3_k127_336133_4	298655.KI912267_gene7073	3.814e-143	465.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_336133_11	298655.KI912267_gene7072	3.722e-77	277.0	COG2244@1|root,COG2244@2|Bacteria,2IAQ4@201174|Actinobacteria	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_336133_5	710111.FraQA3DRAFT_3282	4.161e-140	469.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMS3_k127_336133_17	909613.UO65_2940	3.546e-21	101.0	COG2456@1|root,COG2456@2|Bacteria,2GQZ0@201174|Actinobacteria,4E5TW@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
MMS3_k127_336133_14	675635.Psed_0180	5.652e-67	239.0	COG0463@1|root,COG0463@2|Bacteria,2GM44@201174|Actinobacteria,4EF6Q@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_336133_9	298655.KI912267_gene7067	8.941e-81	287.0	COG1807@1|root,COG1807@2|Bacteria,2IITJ@201174|Actinobacteria	201174|Actinobacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_336133_3	298654.FraEuI1c_1911	2.154e-228	717.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria,4ETUQ@85013|Frankiales	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMS3_k127_336133_12	656024.FsymDg_2263	3.308e-71	256.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
MMS3_k127_336133_7	526225.Gobs_4444	4.832e-101	349.0	COG5305@1|root,COG5305@2|Bacteria,2HTG8@201174|Actinobacteria,4ESH8@85013|Frankiales	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_336133_8	1120936.KB907209_gene1794	1.757e-81	281.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4EM9K@85012|Streptosporangiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_336133_13	1120936.KB907209_gene1793	8.804e-69	246.0	COG1173@1|root,COG1173@2|Bacteria,2IB56@201174|Actinobacteria	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_336133_18	1120936.KB907209_gene1792	1.277e-17	95.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,oligo_HPY
MMS3_k127_3364548_19	1313172.YM304_42840	1.129e-76	264.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CMXK@84992|Acidimicrobiia	84992|Acidimicrobiia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
MMS3_k127_3364548_14	1313172.YM304_42850	1.035e-111	378.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CMSR@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMS3_k127_3364548_31	1121877.JQKF01000017_gene195	2.505e-31	140.0	COG0357@1|root,COG0357@2|Bacteria,2HGHA@201174|Actinobacteria,4CNEN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal RNA small subunit methyltransferase G	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
MMS3_k127_3364548_28	1313172.YM304_42870	3.367e-48	184.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4CN3J@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative single-stranded nucleic acids-binding domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,R3H
MMS3_k127_3364548_26	525909.Afer_2035	1.265e-55	209.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CN42@84992|Acidimicrobiia	84992|Acidimicrobiia	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
MMS3_k127_3364548_34	1313172.YM304_42890	3.396e-19	95.0	COG0759@1|root,COG0759@2|Bacteria,2HH1R@201174|Actinobacteria,4CP20@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
MMS3_k127_3364548_39	351607.Acel_2160	3.599e-06	53.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4ET9K@85013|Frankiales	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0008150,GO:0040007	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
MMS3_k127_3364548_36	525909.Afer_2038	7.907e-13	70.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4CP4C@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
MMS3_k127_3364548_12	1313172.YM304_00010	9.07e-130	434.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CMQT@84992|Acidimicrobiia	84992|Acidimicrobiia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
MMS3_k127_3364548_15	1229780.BN381_100168	1.046e-91	314.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,3UWB4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
MMS3_k127_3364548_18	1313172.YM304_00030	6.678e-84	291.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CN4M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
MMS3_k127_3364548_38	469371.Tbis_0005	8.439e-10	67.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4E3Q7@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0232 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
MMS3_k127_3364548_2	1449346.JQMO01000003_gene4380	4.684e-223	709.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,2M29Y@2063|Kitasatospora	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMS3_k127_3364548_0	525909.Afer_0006	1.078e-309	971.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CMSQ@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA Topoisomerase IV	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMS3_k127_3364548_30	1170562.Cal6303_5300	4.028e-40	157.0	COG0681@1|root,COG0681@2|Bacteria,1G519@1117|Cyanobacteria,1HJIP@1161|Nostocales	1117|Cyanobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
MMS3_k127_3364548_4	227882.SAV_3799	1.281e-217	699.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
MMS3_k127_3364548_7	1048339.KB913029_gene3712	1.358e-162	522.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
MMS3_k127_3364548_10	58123.JOFJ01000024_gene3509	5.15e-141	454.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4EHSR@85012|Streptosporangiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_3364548_1	298654.FraEuI1c_5304	4.975e-242	758.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ERZH@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3364548_22	1313172.YM304_20250	1.203e-74	281.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CN02@84992|Acidimicrobiia	84992|Acidimicrobiia	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
MMS3_k127_3364548_33	1000565.METUNv1_00686	3.436e-21	102.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,Cache_3-Cache_2,EAL,GGDEF,LapD_MoxY_N,PAS,PAS_3,PAS_4,PAS_9
MMS3_k127_3364548_24	269800.Tfu_2950	2.722e-73	255.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4EIAM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_3364548_16	351607.Acel_0516	9.606e-90	309.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4EXC4@85013|Frankiales	201174|Actinobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
MMS3_k127_3364548_17	1380390.JIAT01000010_gene4575	2.107e-84	301.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_3364548_20	1206737.BAGF01000150_gene6107	2.34e-75	272.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria,4FXE2@85025|Nocardiaceae	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_3364548_9	345341.KUTG_01666	2.131e-143	478.0	COG0477@1|root,COG0477@2|Bacteria,2I5V9@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3364548_5	477641.MODMU_2054	1.09e-215	713.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2I5GH@201174|Actinobacteria,4EX4D@85013|Frankiales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
MMS3_k127_3364548_27	1313172.YM304_02170	4.492e-54	197.0	COG1716@1|root,COG1716@2|Bacteria,2HG8X@201174|Actinobacteria,4CN6T@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
MMS3_k127_3364548_35	1313172.YM304_02160	2.168e-15	84.0	COG1716@1|root,COG1716@2|Bacteria,2HGEP@201174|Actinobacteria,4CNCQ@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMS3_k127_3364548_25	1229780.BN381_70017	4.842e-62	240.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,3UWNU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
MMS3_k127_3364548_11	525909.Afer_0087	1.068e-134	454.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CMUZ@84992|Acidimicrobiia	84992|Acidimicrobiia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
MMS3_k127_3364548_21	321332.CYB_2417	3.637e-75	261.0	COG0512@1|root,COG0512@2|Bacteria,1G0QK@1117|Cyanobacteria,1GZ8F@1129|Synechococcus	1117|Cyanobacteria	EH	Anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMS3_k127_3364548_40	590998.Celf_0024	7.035e-05	49.0	2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,4F1I0@85016|Cellulomonadaceae	201174|Actinobacteria	D	Involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
MMS3_k127_3364548_6	1313172.YM304_01060	1.386e-164	529.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_3364548_29	1211815.CBYP010000067_gene112	5.676e-48	176.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_3364548_37	1463858.JOHR01000005_gene1155	2.463e-10	71.0	COG1040@1|root,COG1040@2|Bacteria,2IFV8@201174|Actinobacteria	201174|Actinobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
MMS3_k127_3364548_3	1449347.JQLN01000004_gene6475	1.596e-218	703.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,2M0PM@2063|Kitasatospora	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_3364548_23	485913.Krac_3313	4.846e-74	266.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi	200795|Chloroflexi	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3364548_8	390989.JOEG01000014_gene3137	1.79e-149	484.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4D9FR@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMS3_k127_3364548_13	479433.Caci_2541	4.488e-115	378.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_3364548_32	68170.KL590580_gene5699	7.414e-31	128.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4E4DR@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
MMS3_k127_3418491_5	1283299.AUKG01000001_gene2313	1.21e-66	239.0	COG1055@1|root,COG1055@2|Bacteria	2|Bacteria	P	arsenite transmembrane transporter activity	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
MMS3_k127_3418491_3	47839.CCAU010000002_gene2501	3.894e-99	339.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,236DS@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMS3_k127_3418491_2	246196.MSMEI_0209	4.169e-112	369.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,234BS@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
MMS3_k127_3418491_0	1254432.SCE1572_44265	4.031e-200	644.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2YU3K@29|Myxococcales	28221|Deltaproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
MMS3_k127_3418491_1	2002.JOEQ01000029_gene8203	8.464e-113	374.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4EM9F@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3418491_7	1206739.BAGJ01000140_gene4229	6.607e-13	71.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria,4G48R@85025|Nocardiaceae	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_3418491_6	1122138.AQUZ01000078_gene6137	4.148e-22	111.0	COG0791@1|root,COG0791@2|Bacteria,2IDIS@201174|Actinobacteria	201174|Actinobacteria	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,PG_binding_1
MMS3_k127_3418491_4	1246995.AFR_04305	2.689e-74	268.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3428804_1	1120972.AUMH01000004_gene1498	1.598e-163	538.0	COG3511@1|root,COG3511@2|Bacteria,1V171@1239|Firmicutes,4HDVY@91061|Bacilli,2796D@186823|Alicyclobacillaceae	91061|Bacilli	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
MMS3_k127_3428804_2	861299.J421_0565	2.733e-150	481.0	COG0667@1|root,COG0667@2|Bacteria,1ZUJP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_3428804_3	1206731.BAGB01000040_gene8192	2.507e-72	254.0	COG1839@1|root,COG1839@2|Bacteria,2IAR3@201174|Actinobacteria,4FYWC@85025|Nocardiaceae	201174|Actinobacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
MMS3_k127_3428804_0	525909.Afer_1606	2.25e-219	709.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CMRD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_3428804_6	1229780.BN381_130035	9.288e-27	121.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,3UWXZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	FR47-like protein	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
MMS3_k127_3428804_7	1229780.BN381_130031	1.476e-23	112.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,3UWTU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
MMS3_k127_3428804_8	1313172.YM304_08930	2.642e-21	106.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4CNEU@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
MMS3_k127_3428804_5	1121877.JQKF01000009_gene511	6.52e-52	189.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CNTZ@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_3428804_4	1313172.YM304_08920	2.957e-67	239.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CN11@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
MMS3_k127_3448919_0	298655.KI912266_gene4987	1.361e-151	481.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4ETPN@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_3448919_5	298654.FraEuI1c_2476	1.599e-111	368.0	COG0235@1|root,COG0235@2|Bacteria,2IDHJ@201174|Actinobacteria	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
MMS3_k127_3448919_3	1429046.RR21198_1177	1.162e-142	466.0	COG1752@1|root,COG1752@2|Bacteria,2HJ6N@201174|Actinobacteria,4G5HY@85025|Nocardiaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMS3_k127_3448919_2	1110697.NCAST_32_08190	1.833e-147	491.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4FXJN@85025|Nocardiaceae	201174|Actinobacteria	L	DNA ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
MMS3_k127_3448919_4	146922.JOFU01000005_gene7071	1.658e-131	431.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria	201174|Actinobacteria	E	PHP domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
MMS3_k127_3448919_1	1137271.AZUM01000008_gene2089	7.838e-149	478.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DY4T@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3448919_7	525909.Afer_1452	6.416e-29	133.0	COG1959@1|root,COG1959@2|Bacteria,2GS0E@201174|Actinobacteria,4CNRF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMS3_k127_3448919_6	1229780.BN381_100028	2.023e-91	311.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
MMS3_k127_3461368_2	1123501.KB902284_gene2190	5.184e-124	418.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2TS28@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
MMS3_k127_3461368_5	1123320.KB889719_gene7198	2.817e-101	334.0	COG0778@1|root,COG0778@2|Bacteria,2I6AB@201174|Actinobacteria	201174|Actinobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_3461368_1	1133849.O3I_041580	2.088e-172	548.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria,4FW5B@85025|Nocardiaceae	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
MMS3_k127_3461368_4	479433.Caci_5229	5.11e-115	378.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS3_k127_3461368_3	479433.Caci_5227	1.928e-115	383.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3461368_0	351607.Acel_1142	7.559e-238	751.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4ERSA@85013|Frankiales	201174|Actinobacteria	V	ABC transporter, transmembrane region	msbA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_3461368_6	1385520.N802_07165	3.388e-09	70.0	2CA6S@1|root,2Z9P6@2|Bacteria,2IAT3@201174|Actinobacteria,4FFFX@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3462319_1	981369.JQMJ01000004_gene6406	8.691e-218	702.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,2NFQS@228398|Streptacidiphilus	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_3462319_26	1229780.BN381_130242	1.246e-33	133.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,3UWY5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
MMS3_k127_3462319_22	468556.AQYG01000046_gene1390	4.616e-49	190.0	2BE8W@1|root,327ZW@2|Bacteria,2HDR0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3462319_27	1306990.BARG01000038_gene4562	5.572e-33	141.0	COG4803@1|root,COG4803@2|Bacteria,2IIN1@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
MMS3_k127_3462319_29	1476876.JOJO01000021_gene804	5.438e-19	91.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
MMS3_k127_3462319_8	1229780.BN381_10199	9.837e-119	415.0	COG5617@1|root,COG5617@2|Bacteria,2H32H@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3462319_28	1522072.IL54_2951	3.03e-23	107.0	COG1309@1|root,COG1309@2|Bacteria,1N7FW@1224|Proteobacteria,2UT5S@28211|Alphaproteobacteria,2K9TN@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_3462319_5	557599.MKAN_29030	5.031e-140	458.0	COG2124@1|root,COG2124@2|Bacteria,2HSPE@201174|Actinobacteria,2353U@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome P-450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_3462319_33	1177594.MIC448_270016	0.0002024	54.0	COG4894@1|root,COG4894@2|Bacteria,2GMU8@201174|Actinobacteria	201174|Actinobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,Scramblase
MMS3_k127_3462319_21	1120950.KB892801_gene1729	2.059e-55	217.0	COG3428@1|root,COG3428@2|Bacteria,2GJCD@201174|Actinobacteria,4DQ4J@85009|Propionibacteriales	201174|Actinobacteria	S	overlaps another CDS with the same product name	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
MMS3_k127_3462319_25	67315.JOBD01000011_gene3087	7.92e-35	140.0	COG3402@1|root,COG3402@2|Bacteria,2IR88@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
MMS3_k127_3462319_13	1229780.BN381_80127	2.712e-103	347.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria,3UXC4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	KR domain	rhlG	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
MMS3_k127_3462319_7	1121877.JQKF01000037_gene1809	1.367e-120	407.0	29BBV@1|root,2ZCHD@2|Bacteria,2I82W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
MMS3_k127_3462319_24	105422.BBPM01000094_gene5281	3.689e-36	156.0	2E39M@1|root,32Y96@2|Bacteria,2IITE@201174|Actinobacteria,2NJ8S@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3462319_18	649638.Trad_2266	7.527e-75	266.0	COG1473@1|root,COG1473@2|Bacteria,1WM7N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3462319_2	561175.KB894096_gene681	4.456e-182	577.0	COG1960@1|root,COG1960@2|Bacteria,2HY6H@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE21	-	-	ko:K00257	-	-	R04547,R04592	RC01942	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3462319_17	298653.Franean1_3902	1.168e-76	261.0	COG5514@1|root,COG5514@2|Bacteria,2IS68@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
MMS3_k127_3462319_20	1041522.MCOL_V215564	1.398e-72	270.0	COG0581@1|root,COG0581@2|Bacteria	2|Bacteria	P	inorganic phosphate transmembrane transporter activity	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS3_k127_3462319_12	1041522.MCOL_V215559	3.872e-105	359.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
MMS3_k127_3462319_11	487521.OCU_40920	3.107e-109	367.0	COG0226@1|root,COG0226@2|Bacteria,2IDU5@201174|Actinobacteria,23CM7@1762|Mycobacteriaceae	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS1	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015698,GO:0016020,GO:0016036,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042301,GO:0042594,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071496,GO:0071944	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMS3_k127_3462319_15	419947.MRA_0941	6.572e-94	318.0	COG1117@1|root,COG1117@2|Bacteria,2H3XA@201174|Actinobacteria,23D22@1762|Mycobacteriaceae	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMS3_k127_3462319_30	1121017.AUFG01000010_gene1659	9.476e-11	73.0	COG0515@1|root,COG0515@2|Bacteria,2HY3S@201174|Actinobacteria,4FJP1@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
MMS3_k127_3462319_32	222534.KB893719_gene1065	8.319e-06	57.0	COG4894@1|root,COG4894@2|Bacteria,2GMU8@201174|Actinobacteria,4ETHZ@85013|Frankiales	201174|Actinobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,Scramblase
MMS3_k127_3462319_14	28444.JODQ01000007_gene5286	1.981e-101	343.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3462319_3	1382306.JNIM01000001_gene2717	5.048e-167	544.0	COG1012@1|root,COG1012@2|Bacteria,2G83P@200795|Chloroflexi	200795|Chloroflexi	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
MMS3_k127_3462319_31	1121877.JQKF01000004_gene1095	1.015e-10	74.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
MMS3_k127_3462319_16	1121877.JQKF01000007_gene994	4.807e-77	274.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CNDB@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
MMS3_k127_3462319_0	1236902.ANAS01000031_gene2832	1.057e-242	765.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4EGGJ@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
MMS3_k127_3462319_4	1123024.AUII01000044_gene601	3.167e-146	471.0	COG1063@1|root,COG1063@2|Bacteria,2GKFG@201174|Actinobacteria,4E0X4@85010|Pseudonocardiales	201174|Actinobacteria	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
MMS3_k127_3462319_10	525909.Afer_1991	1.436e-112	372.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4CNHS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_3462319_23	1125863.JAFN01000001_gene1040	3.274e-47	176.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
MMS3_k127_3462319_9	1229780.BN381_150040	1.205e-116	399.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,3UWAK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
MMS3_k127_3462319_19	1313172.YM304_37150	1.297e-74	262.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CN1B@84992|Acidimicrobiia	84992|Acidimicrobiia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
MMS3_k127_3462319_6	1463934.JOCF01000083_gene5476	4.275e-121	396.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
MMS3_k127_3472444_20	1048339.KB913029_gene2112	1.211e-24	108.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4ESHT@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
MMS3_k127_3472444_13	1229780.BN381_40081	6.319e-50	184.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,3UWTG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_3472444_1	1463845.JOIG01000002_gene2347	2.413e-223	721.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
MMS3_k127_3472444_15	1122182.KB903836_gene5128	1.506e-45	169.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4DE4E@85008|Micromonosporales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
MMS3_k127_3472444_14	469371.Tbis_1693	6.198e-49	179.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4E2ZJ@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
MMS3_k127_3472444_18	105425.BBPL01000087_gene4926	1.66e-34	147.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,2NH9A@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
MMS3_k127_3472444_16	525909.Afer_1128	1.092e-42	162.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CN3Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
MMS3_k127_3472444_24	1035191.HMPREF0185_00684	0.0005094	51.0	COG3895@1|root,COG3895@2|Bacteria,1PPHA@1224|Proteobacteria,2UNU4@28211|Alphaproteobacteria,2KJGF@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function (DUF4232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4232,MliC
MMS3_k127_3472444_8	1120973.AQXL01000122_gene131	6.588e-92	313.0	COG0604@1|root,COG0604@2|Bacteria,1TPGR@1239|Firmicutes,4HACF@91061|Bacilli,2794H@186823|Alicyclobacillaceae	91061|Bacilli	C	Zinc-binding dehydrogenase	yhfP	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3472444_3	1432055.GLUCORHAEAF1_16240	6.062e-124	421.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2JQSF@204441|Rhodospirillales	204441|Rhodospirillales	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_3472444_12	1121877.JQKF01000100_gene2	5.929e-58	220.0	2ATXZ@1|root,31JHI@2|Bacteria,2GN21@201174|Actinobacteria,4CNNN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS3_k127_3472444_23	1121877.JQKF01000029_gene2104	2.265e-11	74.0	2B87Q@1|root,321GA@2|Bacteria,2HGVA@201174|Actinobacteria,4CNW4@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3472444_10	263358.VAB18032_00940	3.187e-70	252.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4DBUE@85008|Micromonosporales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
MMS3_k127_3472444_6	1048339.KB913029_gene4376	3.901e-105	352.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4ES56@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0008150,GO:0040007	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
MMS3_k127_3472444_4	105425.BBPL01000018_gene33	5.523e-123	404.0	COG1840@1|root,COG1840@2|Bacteria,2HG0C@201174|Actinobacteria,2NE8P@228398|Streptacidiphilus	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
MMS3_k127_3472444_2	105425.BBPL01000018_gene34	5.734e-164	533.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria,2NFT6@228398|Streptacidiphilus	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
MMS3_k127_3472444_7	105425.BBPL01000018_gene35	5.405e-103	359.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,2NI1E@228398|Streptacidiphilus	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
MMS3_k127_3472444_17	1229780.BN381_40086	7.754e-39	151.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,3UWPC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMS3_k127_3472444_21	671143.DAMO_2813	3.141e-24	113.0	COG1102@1|root,COG1102@2|Bacteria,2NRB0@2323|unclassified Bacteria	2|Bacteria	F	Cytidylate kinase-like family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
MMS3_k127_3472444_5	1229780.BN381_40087	3.368e-117	387.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,3UWIC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
MMS3_k127_3472444_0	710696.Intca_3595	0.0	1323.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4FF6T@85021|Intrasporangiaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
MMS3_k127_3472444_22	1380354.JIAN01000005_gene2080	4.035e-22	102.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria,4F1HV@85016|Cellulomonadaceae	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
MMS3_k127_3472444_19	1380347.JNII01000011_gene815	1.248e-26	117.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,4ETDI@85013|Frankiales	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
MMS3_k127_3472444_9	561175.KB894102_gene1035	3.453e-90	303.0	COG4221@1|root,COG4221@2|Bacteria,2GQNJ@201174|Actinobacteria,4EIKG@85012|Streptosporangiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3472444_11	1122939.ATUD01000001_gene22	7.249e-66	235.0	COG0317@1|root,COG3973@1|root,COG0317@2|Bacteria,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4CRMK@84995|Rubrobacteria	84995|Rubrobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19
MMS3_k127_3492_3	298654.FraEuI1c_1928	2.12e-125	407.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3492_10	33876.JNXY01000015_gene7442	1.466e-21	105.0	COG0645@1|root,COG0645@2|Bacteria,2HWNT@201174|Actinobacteria,4DJQ2@85008|Micromonosporales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3492_9	525909.Afer_1986	7.548e-22	112.0	COG2385@1|root,COG4733@1|root,COG2385@2|Bacteria,COG4733@2|Bacteria,2HGMX@201174|Actinobacteria,4CNMU@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Peptidase A4 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A4
MMS3_k127_3492_6	543632.JOJL01000036_gene3013	2.221e-73	275.0	COG1520@1|root,COG1520@2|Bacteria,2I9FJ@201174|Actinobacteria	201174|Actinobacteria	M	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
MMS3_k127_3492_1	1123320.KB889747_gene7192	1.545e-188	606.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	fadD19	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576	6.2.1.42	ko:K00666,ko:K18688	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3492_8	1048339.KB913029_gene5056	5.625e-34	136.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_3492_0	1229780.BN381_80236	3.237e-209	662.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,3UXSB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3492_2	1229780.BN381_80237	4.849e-159	510.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3492_7	673860.AciM339_0318	1.443e-56	201.0	COG1731@1|root,arCOG01322@2157|Archaea,2XX0K@28890|Euryarchaeota,3F2K2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	6,7-dimethyl-8-ribityllumazine synthase	ribC	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
MMS3_k127_3492_5	1463821.JOGR01000007_gene285	5.729e-109	370.0	COG0161@1|root,COG0161@2|Bacteria,2I2DN@201174|Actinobacteria,4EY5T@85014|Glycomycetales	201174|Actinobacteria	H	Aminotransferase class-III	-	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_3492_4	1229780.BN381_350072	1.046e-113	391.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,3UXC7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Aminotransferase class I and II	bioF	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.1.47,6.2.1.14	ko:K00652,ko:K01906	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03209,R03210,R10124	RC00004,RC00014,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv1569	Aminotran_1_2
MMS3_k127_3509588_2	1283287.KB822580_gene1598	1.179e-62	233.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4DQMQ@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3509588_4	1188256.BASI01000002_gene3370	5.297e-42	158.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2U962@28211|Alphaproteobacteria,3FD92@34008|Rhodovulum	28211|Alphaproteobacteria	S	Cupin superfamily (DUF985)	MA20_39615	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
MMS3_k127_3509588_0	351607.Acel_1984	0.0	1033.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4ERWG@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS3_k127_3509588_1	1267580.AF6_2652	4.569e-88	304.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,21V2P@150247|Anoxybacillus	91061|Bacilli	I	Thiolase, C-terminal domain	mmgA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
MMS3_k127_3509588_3	1463820.JOGW01000009_gene817	2.252e-46	178.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria	201174|Actinobacteria	EGP	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_3509588_5	1123320.KB889741_gene5330	1.255e-09	63.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,2GMPK@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
MMS3_k127_3535979_13	1121468.AUBR01000053_gene1603	2.844e-25	113.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42F9X@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
MMS3_k127_3535979_15	1229780.BN381_130143	2.432e-11	71.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3535979_16	68570.DC74_5400	9.186e-06	53.0	29M6R@1|root,30846@2|Bacteria,2IS04@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3535979_0	525909.Afer_1871	4.958e-238	771.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CMW1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
MMS3_k127_3535979_9	1313172.YM304_05090	2.102e-31	141.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
MMS3_k127_3535979_10	1449346.JQMO01000003_gene3230	8.536e-30	134.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,2M26W@2063|Kitasatospora	201174|Actinobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
MMS3_k127_3535979_8	1313172.YM304_05060	1.703e-35	146.0	COG1413@1|root,COG1413@2|Bacteria,2HA0J@201174|Actinobacteria,4CNCY@84992|Acidimicrobiia	84992|Acidimicrobiia	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
MMS3_k127_3535979_3	1313172.YM304_09040	7.321e-135	436.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	201174|Actinobacteria	D	Cell division protein FtsA	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS3_k127_3535979_14	745014.OMB55_00008560	2.303e-11	76.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_3535979_4	1313172.YM304_07800	1.993e-51	197.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4CNC4@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
MMS3_k127_3535979_11	1313172.YM304_07670	4.171e-27	114.0	2FBA6@1|root,343GA@2|Bacteria,2H78Y@201174|Actinobacteria,4CN8Z@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3535979_12	1313172.YM304_07660	1.425e-25	108.0	2CC1Y@1|root,32TCV@2|Bacteria,2HGD4@201174|Actinobacteria,4CNAQ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
MMS3_k127_3535979_5	926550.CLDAP_31470	6.957e-44	171.0	COG3643@1|root,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
MMS3_k127_3535979_7	1229780.BN381_130084	3.051e-38	145.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,3UWSD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whmD	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
MMS3_k127_3535979_6	298655.KI912266_gene1216	4.425e-41	161.0	COG1309@1|root,COG1309@2|Bacteria,2HD07@201174|Actinobacteria,4EW8M@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_3535979_1	1313172.YM304_07620	2.156e-213	681.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4CMU5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3535979_2	1313172.YM304_07520	1.329e-183	590.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4CMSG@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mg-chelatase subunit ChlI	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
MMS3_k127_3596845_8	1216976.AX27061_4200	1.519e-33	142.0	COG2120@1|root,COG2120@2|Bacteria,1RI1F@1224|Proteobacteria,2VSXD@28216|Betaproteobacteria,3T43D@506|Alcaligenaceae	28216|Betaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_3596845_2	68260.JOAY01000027_gene4202	3.826e-86	299.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
MMS3_k127_3596845_3	67257.JODR01000003_gene1618	2.624e-79	274.0	COG1028@1|root,COG1028@2|Bacteria,2GM6W@201174|Actinobacteria	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities related to short-chain alcohol dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
MMS3_k127_3596845_7	557599.MKAN_27890	3.944e-59	209.0	COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria,238QQ@1762|Mycobacteriaceae	201174|Actinobacteria	O	Peroxiredoxin	bcpB	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS3_k127_3596845_4	351607.Acel_0088	1.113e-74	258.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4ERYJ@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_3596845_6	1123320.KB889700_gene9200	6.642e-64	223.0	COG3467@1|root,COG3467@2|Bacteria,2IFJS@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
MMS3_k127_3596845_1	1229780.BN381_10328	1.385e-161	522.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,3UX6E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_3596845_5	1229780.BN381_10244	1.441e-66	252.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3596845_0	1229780.BN381_10243	1.114e-262	842.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMS3_k127_3600331_5	525909.Afer_1266	5.896e-110	359.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
MMS3_k127_3600331_8	1313172.YM304_24220	2.092e-56	220.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CN8K@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
MMS3_k127_3600331_6	1313172.YM304_21150	9.201e-96	329.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CNTM@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_3600331_1	1121877.JQKF01000022_gene2268	3.622e-199	657.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CMWI@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
MMS3_k127_3600331_7	1121877.JQKF01000003_gene1542	2.794e-85	306.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4CN0Y@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_3600331_3	1283283.ATXA01000021_gene2882	1.649e-118	390.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ES16@85013|Frankiales	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_3600331_9	1449976.KALB_558	1.975e-21	100.0	COG1846@1|root,COG1846@2|Bacteria,2GRCT@201174|Actinobacteria,4E3NB@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_3600331_0	1313172.YM304_22750	0.0	1196.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4CMX0@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS3_k127_3600331_2	1229780.BN381_330110	3.595e-160	526.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,3UWAA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
MMS3_k127_3600331_4	1229780.BN381_330111	2.477e-110	373.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_3615175_1	525909.Afer_0638	1.92e-276	862.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CMS2@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
MMS3_k127_3615175_19	565045.NOR51B_928	0.0008164	48.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
MMS3_k127_3615175_11	1229780.BN381_330073	1.01e-73	260.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,3UWK5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
MMS3_k127_3615175_9	1313172.YM304_16060	2.46e-86	302.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CN39@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
MMS3_k127_3615175_17	589865.DaAHT2_1876	5.36e-28	125.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2MKH5@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
MMS3_k127_3615175_0	525909.Afer_0643	2.822e-302	946.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CMSF@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,S1
MMS3_k127_3615175_6	28444.JODQ01000001_gene2720	1.982e-117	391.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4EHPV@85012|Streptosporangiales	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_3615175_10	1229780.BN381_330092	9.774e-76	263.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,3UWJR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
MMS3_k127_3615175_12	351607.Acel_0013	7.232e-50	190.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4ESUX@85013|Frankiales	201174|Actinobacteria	NU	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
MMS3_k127_3615175_18	471852.Tcur_3905	1.033e-16	90.0	COG1309@1|root,COG1309@2|Bacteria,2IPMI@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_3615175_4	1229780.BN381_80295	2.405e-135	446.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
MMS3_k127_3615175_7	1229780.BN381_80296	2.153e-95	321.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,3UWKM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_3615175_2	1313172.YM304_16400	6.666e-207	662.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CMS5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Zn-dependent metallo-hydrolase RNA specificity domain	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
MMS3_k127_3615175_14	1288079.AUKN01000001_gene4037	4.245e-37	159.0	COG0584@1|root,COG0584@2|Bacteria,2GM3M@201174|Actinobacteria	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ1	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
MMS3_k127_3615175_13	1136417.AZWE01000067_gene608	2.021e-44	177.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4DH4M@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
MMS3_k127_3615175_5	1306174.JODP01000016_gene7073	3.791e-124	434.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
MMS3_k127_3615175_8	298653.Franean1_1963	7.85e-95	323.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4ERCS@85013|Frankiales	201174|Actinobacteria	L	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_3615175_3	1313172.YM304_16440	6.799e-182	616.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CMSW@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
MMS3_k127_3615175_15	543632.JOJL01000027_gene2713	1.057e-36	148.0	COG1686@1|root,COG1686@2|Bacteria,2GM2X@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
MMS3_k127_3638120_14	298655.KI912266_gene5601	4.56e-47	184.0	COG1309@1|root,COG1309@2|Bacteria,2GK0V@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_3638120_17	1449347.JQLN01000007_gene1924	2.3e-34	139.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria,2M2T4@2063|Kitasatospora	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
MMS3_k127_3638120_7	1151122.AQYD01000007_gene1042	6.273e-85	304.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4FMP6@85023|Microbacteriaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3638120_20	28444.JODQ01000006_gene618	2.014e-19	101.0	28JAE@1|root,2Z957@2|Bacteria,2I3IM@201174|Actinobacteria,4EJIB@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
MMS3_k127_3638120_2	1160137.KB907307_gene630	1.342e-137	457.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4FVHF@85025|Nocardiaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
MMS3_k127_3638120_21	443218.AS9A_2125	8.082e-19	101.0	COG1073@1|root,COG1073@2|Bacteria,2IFI1@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_3638120_13	326424.FRAAL3677	1.794e-50	195.0	COG0586@1|root,COG0586@2|Bacteria,2IA3P@201174|Actinobacteria	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_3638120_6	251221.35213801	1.595e-85	302.0	COG2723@1|root,COG2723@2|Bacteria,1G3QH@1117|Cyanobacteria	1117|Cyanobacteria	G	Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
MMS3_k127_3638120_19	349163.Acry_0765	1.126e-19	102.0	2DM5C@1|root,31SFK@2|Bacteria,1RHYU@1224|Proteobacteria,2UIDQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3638120_9	1298863.AUEP01000011_gene498	1.202e-75	262.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4DQC5@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	caiD	-	4.2.1.149,4.2.1.17	ko:K01692,ko:K08299,ko:K16426	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01055,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01055,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06625,R06942,R08093,R10675	RC00004,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02933	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1,Polyketide_cyc2
MMS3_k127_3638120_15	525909.Afer_1989	3.476e-35	140.0	2E8WU@1|root,3336Z@2|Bacteria,2GR5V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3638120_23	1121877.JQKF01000003_gene1548	0.0004135	46.0	COG1826@1|root,COG1826@2|Bacteria,2HH2I@201174|Actinobacteria,4CP2H@84992|Acidimicrobiia	84992|Acidimicrobiia	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_3638120_1	68199.JNZO01000001_gene1148	6.811e-152	492.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
MMS3_k127_3638120_11	1121877.JQKF01000003_gene1554	9.581e-63	228.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4CN92@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
MMS3_k127_3638120_0	1121877.JQKF01000003_gene1553	6.42e-264	824.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CMUD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
MMS3_k127_3638120_22	365528.KB891203_gene3448	2.954e-10	67.0	2D9MJ@1|root,32TTI@2|Bacteria,2IFFM@201174|Actinobacteria,4ETA5@85013|Frankiales	201174|Actinobacteria	C	Belongs to the cytochrome c oxidase bacterial subunit CtaF family	ctaF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
MMS3_k127_3638120_4	1123065.ATWL01000006_gene2201	9.685e-100	340.0	COG0477@1|root,COG2814@2|Bacteria,2GMWE@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_3638120_3	1449346.JQMO01000003_gene4703	3.529e-126	407.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2GNW2@201174|Actinobacteria,2M3WE@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
MMS3_k127_3638120_5	1380393.JHVP01000001_gene2518	1.298e-87	312.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,4EX9U@85013|Frankiales	201174|Actinobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
MMS3_k127_3638120_18	1125863.JAFN01000001_gene2653	1.529e-27	129.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WPGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
MMS3_k127_3638120_16	929712.KI912613_gene4618	4.611e-35	143.0	COG2114@1|root,COG2114@2|Bacteria,2ICJJ@201174|Actinobacteria,4CQDR@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
MMS3_k127_3638120_8	1206741.BAFX01000185_gene7589	8.311e-78	276.0	COG0265@1|root,COG0265@2|Bacteria,2GJJ3@201174|Actinobacteria,4FWGG@85025|Nocardiaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_3638120_12	1123256.KB907925_gene1470	2.444e-56	207.0	COG1028@1|root,COG1028@2|Bacteria,1R4UB@1224|Proteobacteria,1SN8X@1236|Gammaproteobacteria,1XCDF@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3638120_10	1123320.KB889562_gene6675	2.096e-68	248.0	COG4221@1|root,COG4221@2|Bacteria,2IGP3@201174|Actinobacteria	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3661228_12	1229780.BN381_450097	9.967e-77	265.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,3UW6S@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
MMS3_k127_3661228_18	1313172.YM304_08260	8.981e-62	229.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CN29@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
MMS3_k127_3661228_33	1229780.BN381_450095	4.797e-26	113.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,3UWUI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
MMS3_k127_3661228_3	1229780.BN381_450094	4.858e-143	459.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,3UWDY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
MMS3_k127_3661228_25	1121877.JQKF01000009_gene544	3.749e-49	175.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CN5R@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
MMS3_k127_3661228_30	1229780.BN381_450092	9.057e-34	149.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,3UWV3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
MMS3_k127_3661228_6	1313172.YM304_08310	3.639e-118	389.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CMU9@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
MMS3_k127_3661228_16	1121877.JQKF01000009_gene541	9.84e-68	239.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4CN0S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
MMS3_k127_3661228_39	1287475.HMPREF1650_04550	3.146e-14	80.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,22NTK@1653|Corynebacteriaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
MMS3_k127_3661228_35	1121877.JQKF01000009_gene539	7.145e-24	106.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4CN9S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
MMS3_k127_3661228_17	525909.Afer_0408	1.034e-65	231.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CMZN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
MMS3_k127_3661228_32	485916.Dtox_0297	2.158e-32	129.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,26260@186807|Peptococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
MMS3_k127_3661228_9	525909.Afer_0410	1.965e-79	280.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CMX7@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
MMS3_k127_3661228_34	1078020.KEK_12083	1.324e-25	109.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,23AM9@1762|Mycobacteriaceae	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
MMS3_k127_3661228_23	1229780.BN381_450083	4.171e-52	186.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,3UWN2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
MMS3_k127_3661228_14	1122933.JNIY01000003_gene646	1.702e-71	245.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4F206@85016|Cellulomonadaceae	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
MMS3_k127_3661228_31	525909.Afer_0414	1.218e-32	135.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4CNBZ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
MMS3_k127_3661228_13	1121877.JQKF01000009_gene532	2.875e-75	259.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CN34@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
MMS3_k127_3661228_38	1313172.YM304_08430	6.426e-16	89.0	COG1841@1|root,COG1841@2|Bacteria,2HGDQ@201174|Actinobacteria,4CNC3@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
MMS3_k127_3661228_24	1229780.BN381_450078	8.355e-52	192.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,3UWM5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
MMS3_k127_3661228_2	1121877.JQKF01000009_gene529	5.866e-172	549.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CMWZ@84992|Acidimicrobiia	84992|Acidimicrobiia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
MMS3_k127_3661228_11	525909.Afer_0419	5.708e-77	264.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CMZ1@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMS3_k127_3661228_7	1121877.JQKF01000009_gene527	2.23e-99	333.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CN1I@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMS3_k127_3661228_0	68170.KL590535_gene3741	7.417e-199	633.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4E527@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
MMS3_k127_3661228_28	1214101.BN159_0270	1.026e-39	156.0	COG2920@1|root,COG2920@2|Bacteria,2IQB2@201174|Actinobacteria	201174|Actinobacteria	P	PFAM DsrC family protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
MMS3_k127_3661228_15	68170.KL590535_gene3743	6.159e-68	240.0	COG2210@1|root,COG2210@2|Bacteria,2IFXH@201174|Actinobacteria,4EABZ@85010|Pseudonocardiales	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
MMS3_k127_3661228_29	525909.Afer_0421	8.35e-37	141.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4CNX6@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
MMS3_k127_3661228_40	562970.Btus_0178	8.446e-10	71.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,278PF@186823|Alicyclobacillaceae	91061|Bacilli	J	to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
MMS3_k127_3661228_21	1121877.JQKF01000009_gene526	5.487e-56	198.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4CN1Z@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
MMS3_k127_3661228_19	525909.Afer_0424	1.001e-58	209.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4CN7A@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
MMS3_k127_3661228_10	525909.Afer_0425	7.668e-78	266.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CN4S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
MMS3_k127_3661228_4	1229780.BN381_450071	1.724e-134	435.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,3UW7R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
MMS3_k127_3661228_27	1229780.BN381_450070	2.883e-41	158.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,3UWTF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
MMS3_k127_3661228_22	1313172.YM304_08770	1.071e-54	207.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CNBD@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
MMS3_k127_3661228_20	1229780.BN381_130023	1.133e-56	209.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,3UWK2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
MMS3_k127_3661228_26	1229780.BN381_130024	1.197e-44	168.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,3UWN9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
MMS3_k127_3661228_5	882083.SacmaDRAFT_0740	5.741e-122	413.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4DXC8@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_3661228_1	1051006.HMPREF1162_2074	1.96e-184	599.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4DNBT@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
MMS3_k127_3661228_36	1313172.YM304_08850	1.009e-22	111.0	COG0736@1|root,COG0736@2|Bacteria,2HGFC@201174|Actinobacteria,4CND0@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
MMS3_k127_3661228_8	1229780.BN381_130028	2.257e-82	297.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,3UXFU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Carbohydrate kinase	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
MMS3_k127_3661228_37	1229780.BN381_130029	4.842e-17	90.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,3UWJZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
MMS3_k127_3754545_16	1380354.JIAN01000009_gene3763	1.355e-15	89.0	COG2311@1|root,COG2311@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	-
MMS3_k127_3754545_14	525909.Afer_0202	3.387e-34	134.0	2E3QT@1|root,31FNG@2|Bacteria,2HGTF@201174|Actinobacteria,4CNV3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3754545_0	796606.BMMGA3_08165	1.404e-149	488.0	COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,1ZCDM@1386|Bacillus	91061|Bacilli	M	Chitin synthase	icaA	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
MMS3_k127_3754545_13	525909.Afer_0201	4.664e-51	209.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CMZJ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
MMS3_k127_3754545_6	1313172.YM304_07750	3.287e-78	287.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_3754545_12	1122611.KB904014_gene6793	4.779e-58	211.0	COG1234@1|root,COG1234@2|Bacteria,2IQCE@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMS3_k127_3754545_1	525909.Afer_0190	5.914e-143	465.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CMQR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Seryl-tRNA synthetase N-terminal domain	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
MMS3_k127_3754545_7	591158.SSMG_02308	5.063e-75	265.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	drrA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3754545_10	106370.Francci3_1654	7.456e-65	237.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4ESTT@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
MMS3_k127_3754545_18	1121877.JQKF01000024_gene2407	6.386e-10	69.0	COG0526@1|root,COG0526@2|Bacteria,2HGGP@201174|Actinobacteria,4CNDV@84992|Acidimicrobiia	84992|Acidimicrobiia	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
MMS3_k127_3754545_3	1229780.BN381_450058	1.096e-106	354.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,3UWHG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
MMS3_k127_3754545_11	656024.FsymDg_1709	7.628e-60	220.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4ESN0@85013|Frankiales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
MMS3_k127_3754545_19	1476876.JOJO01000003_gene5609	3.577e-05	55.0	2EAJ3@1|root,33CYM@2|Bacteria,2I425@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2510)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510
MMS3_k127_3754545_15	1380393.JHVP01000013_gene3428	4.448e-26	116.0	COG0515@1|root,COG0515@2|Bacteria	1380393.JHVP01000013_gene3428|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3754545_17	1356854.N007_15760	9.968e-13	81.0	COG1289@1|root,COG1289@2|Bacteria	2|Bacteria	S	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
MMS3_k127_3754545_9	985054.JQEZ01000003_gene1251	3.564e-69	246.0	COG2433@1|root,COG3618@1|root,COG2433@2|Bacteria,COG3618@2|Bacteria,1RJ1Q@1224|Proteobacteria,2U9U2@28211|Alphaproteobacteria,4ND8T@97050|Ruegeria	28211|Alphaproteobacteria	S	zinc-finger binding domain of transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
MMS3_k127_3754545_5	1123023.JIAI01000001_gene6349	2.652e-79	275.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4E2K4@85010|Pseudonocardiales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
MMS3_k127_3754545_2	882082.SaccyDRAFT_3131	1.729e-111	377.0	2CE4Q@1|root,2Z7WX@2|Bacteria,2H0P6@201174|Actinobacteria,4E993@85010|Pseudonocardiales	201174|Actinobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
MMS3_k127_3754545_4	351016.RAZWK3B_12192	3.579e-82	287.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria,2P2CM@2433|Roseobacter	28211|Alphaproteobacteria	H	pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	rfbE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_3754545_8	1283283.ATXA01000006_gene1856	2.412e-73	265.0	COG4129@1|root,COG4129@2|Bacteria,2I3V3@201174|Actinobacteria	201174|Actinobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
MMS3_k127_3814749_13	1283283.ATXA01000019_gene2902	9.087e-48	184.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS3_k127_3814749_15	1229780.BN381_250095	2.671e-24	104.0	COG1141@1|root,COG1141@2|Bacteria,2GT1Y@201174|Actinobacteria	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	fdxD_2	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
MMS3_k127_3814749_8	1370121.AUWS01000049_gene1391	2.194e-70	246.0	COG1309@1|root,COG1309@2|Bacteria,2I8Z7@201174|Actinobacteria,234JD@1762|Mycobacteriaceae	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_3814749_1	365528.KB891137_gene412	3.979e-217	683.0	COG2124@1|root,COG2124@2|Bacteria,2GNZS@201174|Actinobacteria,4EUB3@85013|Frankiales	201174|Actinobacteria	Q	PFAM Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_3814749_5	222534.KB893752_gene4119	7.988e-102	345.0	COG2084@1|root,COG2084@2|Bacteria,2I9EJ@201174|Actinobacteria	201174|Actinobacteria	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_3814749_12	285535.JOEY01000006_gene8117	3.077e-49	186.0	COG0599@1|root,COG0599@2|Bacteria,2GPXI@201174|Actinobacteria	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_3814749_2	710685.MycrhN_3987	4.092e-192	607.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,2341E@1762|Mycobacteriaceae	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_3814749_6	1122247.C731_0287	1.767e-99	332.0	COG2175@1|root,COG2175@2|Bacteria,2GNUC@201174|Actinobacteria,235P9@1762|Mycobacteriaceae	201174|Actinobacteria	Q	taurine catabolism dioxygenase	tfdA	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
MMS3_k127_3814749_7	1278078.G419_25814	1.022e-90	306.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4FXDV@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3814749_4	436229.JOEH01000021_gene7730	6.153e-121	398.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3814749_14	1116232.AHBF01000133_gene2009	1.515e-34	149.0	COG1309@1|root,COG1309@2|Bacteria,2GNJZ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_3814749_10	436229.JOEH01000021_gene7745	7.141e-50	197.0	COG4319@1|root,COG4319@2|Bacteria,2IFX9@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMS3_k127_3814749_3	1172185.KB911525_gene3969	4.952e-129	422.0	COG1960@1|root,COG1960@2|Bacteria,2GKYN@201174|Actinobacteria,4FVVF@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3814749_11	487521.OCU_13200	2e-49	191.0	COG1960@1|root,COG1960@2|Bacteria,2GM6Q@201174|Actinobacteria,236IZ@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
MMS3_k127_3814749_0	298655.KI912266_gene3118	1.982e-253	788.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_3814749_9	298654.FraEuI1c_5408	5.216e-63	243.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,4ES18@85013|Frankiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain protein	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
MMS3_k127_3817422_2	1229780.BN381_130019	2.162e-232	753.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,3UWF7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_3817422_14	525909.Afer_1951	4.053e-25	110.0	2A58G@1|root,30TXM@2|Bacteria,2HG9Z@201174|Actinobacteria,4CN8R@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3817422_11	1278073.MYSTI_00750	8.098e-60	218.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,43C34@68525|delta/epsilon subdivisions,2WQEN@28221|Deltaproteobacteria,2YVEG@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3817422_9	1229780.BN381_130016	3.253e-83	281.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,3UWG1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
MMS3_k127_3817422_15	1229780.BN381_130015	4.455e-16	91.0	COG1828@1|root,COG1828@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
MMS3_k127_3817422_7	1229780.BN381_130013	5.401e-92	313.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,3UWES@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
MMS3_k127_3817422_4	1313172.YM304_38920	1.545e-153	500.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4CMWU@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
MMS3_k127_3817422_6	1121877.JQKF01000006_gene933	4.872e-110	375.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CMZB@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
MMS3_k127_3817422_3	1229780.BN381_130003	3.439e-202	636.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,3UWF4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
MMS3_k127_3817422_10	1246995.AFR_04305	1.19e-65	254.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3817422_0	1121877.JQKF01000006_gene914	0.0	1072.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CMTX@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal, D2-small domain, of ClpB protein	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS3_k127_3817422_12	525909.Afer_1963	2.1e-38	148.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CN4Z@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
MMS3_k127_3817422_5	525909.Afer_1962	2.37e-128	419.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CMRG@84992|Acidimicrobiia	84992|Acidimicrobiia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS3_k127_3817422_13	525909.Afer_1961	5.152e-29	123.0	COG0576@1|root,COG0576@2|Bacteria,2HGAI@201174|Actinobacteria,4CN9N@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
MMS3_k127_3817422_1	525909.Afer_1960	1.271e-310	961.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CMVI@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
MMS3_k127_3817422_8	471857.Svir_02670	1.113e-88	301.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4DY3Y@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
MMS3_k127_3836999_0	471852.Tcur_1862	1.105e-202	644.0	COG0511@1|root,COG4799@1|root,COG0511@2|Bacteria,COG4799@2|Bacteria,2I46V@201174|Actinobacteria	201174|Actinobacteria	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl,Carboxyl_trans
MMS3_k127_3836999_3	479431.Namu_0278	7.292e-109	364.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4EU45@85013|Frankiales	201174|Actinobacteria	M	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
MMS3_k127_3836999_10	405948.SACE_0308	1.878e-23	103.0	2E3SC@1|root,32YPX@2|Bacteria,2HPCF@201174|Actinobacteria,4E4BJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
MMS3_k127_3836999_9	1449069.JMLO01000001_gene1783	1.938e-47	175.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria,4G1A2@85025|Nocardiaceae	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_3
MMS3_k127_3836999_6	994479.GL877882_gene6853	3.054e-86	300.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4DXF2@85010|Pseudonocardiales	201174|Actinobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3,1.1.3.46	ko:K00101,ko:K16422	ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130	-	R00196,R06633	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
MMS3_k127_3836999_7	1194972.MVAC_05972	9.821e-71	250.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,235DT@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_3836999_11	1122609.AUGT01000017_gene900	9.817e-06	54.0	COG1846@1|root,COG1846@2|Bacteria,2GR49@201174|Actinobacteria,4DSWQ@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_3836999_2	1229780.BN381_510008	1.756e-117	400.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3836999_8	298655.KI912267_gene6855	3.655e-64	228.0	COG1028@1|root,COG1028@2|Bacteria,2GKT2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_3836999_5	1150599.MPHLEI_09739	2.788e-87	295.0	COG1028@1|root,COG1028@2|Bacteria,2HFC2@201174|Actinobacteria,23CP0@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3836999_4	1229780.BN381_130389	2.884e-102	343.0	COG1028@1|root,COG1028@2|Bacteria,2HQ7H@201174|Actinobacteria,3UXHT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3836999_1	1123320.KB889697_gene8995	4.26e-135	437.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_3838204_3	1229780.BN381_20098	8.351e-68	244.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,3UWNZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
MMS3_k127_3838204_2	1313172.YM304_33050	1.46e-71	260.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CN5A@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	-	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
MMS3_k127_3838204_7	469616.FMAG_00922	6.654e-05	53.0	COG0797@1|root,COG0797@2|Bacteria,37ABW@32066|Fusobacteria	32066|Fusobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
MMS3_k127_3838204_1	1313172.YM304_33030	1.982e-73	261.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CN2X@84992|Acidimicrobiia	84992|Acidimicrobiia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
MMS3_k127_3838204_0	1121877.JQKF01000013_gene252	4.892e-152	499.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CMP6@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
MMS3_k127_3838204_4	590998.Celf_3079	2.733e-64	231.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4F1XK@85016|Cellulomonadaceae	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
MMS3_k127_3838204_6	1313172.YM304_32980	3.328e-18	88.0	COG1430@1|root,COG1430@2|Bacteria,2IKSE@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
MMS3_k127_3838204_5	1121937.AUHJ01000011_gene2894	7.589e-52	195.0	COG0584@1|root,COG3391@1|root,COG0584@2|Bacteria,COG3391@2|Bacteria,1MW6Z@1224|Proteobacteria,1S3SX@1236|Gammaproteobacteria,468V3@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
MMS3_k127_3851503_0	222534.KB893681_gene1083	1.416e-186	597.0	COG4584@1|root,COG4584@2|Bacteria,2GZ8H@201174|Actinobacteria,4EWKX@85013|Frankiales	201174|Actinobacteria	L	Evidence 2b Function of strongly homologous gene	istA	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
MMS3_k127_3851503_1	675635.Psed_1257	3.394e-117	383.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4E2EK@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM IstB-like ATP-binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
MMS3_k127_3851503_2	1127134.NOCYR_4995	5.881e-34	137.0	COG2329@1|root,COG2329@2|Bacteria,2HUXC@201174|Actinobacteria,4G7M4@85025|Nocardiaceae	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3860118_5	497964.CfE428DRAFT_0889	4.027e-83	295.0	COG0128@1|root,COG0128@2|Bacteria,46SFD@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
MMS3_k127_3860118_2	1313172.YM304_24990	5.755e-92	317.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CNBS@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
MMS3_k127_3860118_10	1121877.JQKF01000026_gene2431	6.105e-37	142.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,4CNUX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
MMS3_k127_3860118_3	1313172.YM304_24980	1.283e-86	297.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4CN36@84992|Acidimicrobiia	84992|Acidimicrobiia	J	RNA pseudouridylate synthase	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMS3_k127_3860118_7	1313172.YM304_24970	1.249e-55	201.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4CN9J@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
MMS3_k127_3860118_6	1229780.BN381_290072	6.469e-59	213.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,3UWJ9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
MMS3_k127_3860118_1	443255.SCLAV_2358	5.209e-108	361.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
MMS3_k127_3860118_8	525909.Afer_1132	7.847e-51	189.0	COG1994@1|root,COG1994@2|Bacteria,2GM8E@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase M50	rip2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
MMS3_k127_3860118_12	1298863.AUEP01000020_gene3620	8.188e-15	78.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4DRE5@85009|Propionibacteriales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
MMS3_k127_3860118_4	1313172.YM304_24920	1.657e-85	298.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CMZU@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_3860118_11	1229780.BN381_290082	7.056e-35	139.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,3UWWT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
MMS3_k127_3860118_0	1121877.JQKF01000002_gene1735	1.951e-213	679.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CMQD@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
MMS3_k127_3860118_9	1229780.BN381_290088	1.043e-40	154.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,3UWCU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
MMS3_k127_391572_1	1120950.KB892757_gene6542	6.644e-207	667.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4DNHX@85009|Propionibacteriales	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
MMS3_k127_391572_0	525909.Afer_0543	3.94e-255	820.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CMQU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
MMS3_k127_391572_14	1229780.BN381_210073	4.034e-31	126.0	2FF8Q@1|root,3476J@2|Bacteria,2H7PN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_391572_7	247156.NFA_3830	1.236e-76	270.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4FU9K@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA21	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_391572_12	479434.Sthe_1524	4.182e-53	209.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
MMS3_k127_391572_15	1121385.AQXW01000004_gene1215	5.619e-24	106.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,1ZW8W@145357|Dermacoccaceae	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
MMS3_k127_391572_10	1038858.AXBA01000010_gene2610	1.191e-59	220.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,3F0B8@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMS3_k127_391572_11	525909.Afer_1145	2.155e-58	221.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CN74@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
MMS3_k127_391572_9	1229780.BN381_210086	1.022e-59	211.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,3UWVS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NifU-like N terminal domain	sufU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMS3_k127_391572_3	1229780.BN381_210087	2.525e-133	445.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,3UWF9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Aminotransferase class-V	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
MMS3_k127_391572_6	525909.Afer_0566	8.657e-96	319.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CMZ6@84992|Acidimicrobiia	84992|Acidimicrobiia	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMS3_k127_391572_5	1229780.BN381_210088	1.273e-96	323.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,3UXGK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_391572_2	1229780.BN381_210093	6.13e-164	528.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,3UXCB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_391572_13	1229780.BN381_210096	2.956e-37	160.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
MMS3_k127_391572_8	477641.MODMU_4726	7.644e-69	248.0	COG0382@1|root,COG0382@2|Bacteria,2GJ6P@201174|Actinobacteria,4EV3I@85013|Frankiales	201174|Actinobacteria	H	UbiA prenyltransferase family	ubiA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016763,GO:0031224,GO:0031226,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046872,GO:0052636,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.2.45	ko:K14136	-	-	R10095	RC00005	ko00000,ko01000,ko01006	-	-	-	UbiA
MMS3_k127_391572_4	1449355.JQNR01000005_gene3820	1.757e-117	398.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.98.3	ko:K16653	-	-	-	-	ko00000,ko01000	-	-	-	ALO,FAD_binding_4
MMS3_k127_3946795_16	1122138.AQUZ01000098_gene7765	4.609e-38	154.0	arCOG03842@1|root,30WW9@2|Bacteria,2IDJ1@201174|Actinobacteria,4DRRZ@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF929
MMS3_k127_3946795_17	1386089.N865_20170	5.325e-37	145.0	COG4243@1|root,COG4243@2|Bacteria,2HGRN@201174|Actinobacteria,4FGUP@85021|Intrasporangiaceae	201174|Actinobacteria	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
MMS3_k127_3946795_9	234621.RER_33750	6.126e-83	278.0	28NTV@1|root,2ZBSB@2|Bacteria,2GS03@201174|Actinobacteria,4FUR6@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMS3_k127_3946795_20	1229780.BN381_170018	2.375e-20	99.0	COG1141@1|root,COG2124@1|root,COG1141@2|Bacteria,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,3UWWV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Cytochrome P450	cyp51	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615	1.14.13.70	ko:K05917	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00101	R05640,R05731	RC01442	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
MMS3_k127_3946795_1	1229780.BN381_170018	9.862e-224	701.0	COG1141@1|root,COG2124@1|root,COG1141@2|Bacteria,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,3UWWV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Cytochrome P450	cyp51	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615	1.14.13.70	ko:K05917	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00101	R05640,R05731	RC01442	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
MMS3_k127_3946795_10	1229780.BN381_170019	2.656e-79	284.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	MA20_43565	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3946795_4	1394178.AWOO02000025_gene4986	2.967e-162	531.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4EHPD@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	cyp123A3	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_3946795_18	1394178.AWOO02000025_gene4987	1.314e-34	143.0	COG1309@1|root,COG1309@2|Bacteria,2I9ZN@201174|Actinobacteria,4EP25@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_3946795_19	36809.MAB_1221	1.894e-30	125.0	COG0599@1|root,COG0599@2|Bacteria,2IFMB@201174|Actinobacteria,238R6@1762|Mycobacteriaceae	201174|Actinobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMS3_k127_3946795_13	471852.Tcur_2587	8.823e-53	197.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4EGMR@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_3946795_8	1120936.KB907210_gene5519	1.169e-88	312.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4EGKE@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3946795_0	298655.KI912266_gene5581	1.069e-226	707.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_3946795_5	1449353.JQMQ01000005_gene5520	3.379e-151	491.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,2NEQU@228398|Streptacidiphilus	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.15	ko:K07544	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
MMS3_k127_3946795_6	471852.Tcur_4820	3.595e-116	388.0	COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4EFXE@85012|Streptosporangiales	201174|Actinobacteria	E	ACT domain	serB	GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	iNJ661.Rv3042c	ACT_6,HAD
MMS3_k127_3946795_11	469371.Tbis_1486	2.1e-69	247.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4DZBZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
MMS3_k127_3946795_7	298654.FraEuI1c_6395	8.052e-105	367.0	COG3266@1|root,COG3266@2|Bacteria,2I302@201174|Actinobacteria,4EUA2@85013|Frankiales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3946795_12	1121877.JQKF01000015_gene104	2.78e-63	231.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4CN8S@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
MMS3_k127_3946795_15	765420.OSCT_0856	9.286e-40	162.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_11,Methyltransf_23
MMS3_k127_3946795_2	1229780.BN381_80311	2.918e-170	542.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,3UW96@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
MMS3_k127_3946795_14	1313172.YM304_05900	6.01e-52	201.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria	201174|Actinobacteria	S	domain protein	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
MMS3_k127_3946795_3	1121946.AUAX01000009_gene4515	1.166e-163	532.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,4DARH@85008|Micromonosporales	201174|Actinobacteria	M	glycosyl transferase, family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_4238354_4	465515.Mlut_15060	1.919e-24	109.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,1W8G0@1268|Micrococcaceae	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
MMS3_k127_4238354_1	1968.JOEV01000021_gene5981	4.487e-114	392.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria	201174|Actinobacteria	E	(mono)amine oxidase	aofH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMS3_k127_4238354_5	1121472.AQWN01000011_gene1307	5.839e-17	87.0	COG3255@1|root,COG3255@2|Bacteria,1V88A@1239|Firmicutes,24KTK@186801|Clostridia,26268@186807|Peptococcaceae	186801|Clostridia	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
MMS3_k127_4238354_3	1051632.TPY_0244	4.173e-77	276.0	COG0531@1|root,COG0531@2|Bacteria,1UW5Y@1239|Firmicutes	1239|Firmicutes	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_4238354_2	1229780.BN381_80411	2.353e-83	289.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,3UWIP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
MMS3_k127_4238354_0	469383.Cwoe_1416	1.223e-171	554.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CRIZ@84995|Rubrobacteria	84995|Rubrobacteria	M	Mur ligase family, glutamate ligase domain	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
MMS3_k127_4238354_6	1123320.KB889697_gene8927	1.47e-11	78.0	COG1652@1|root,COG3629@1|root,COG1652@2|Bacteria,COG3629@2|Bacteria,2I8YV@201174|Actinobacteria	201174|Actinobacteria	NU	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,LysM
MMS3_k127_4267990_0	1120950.KB892801_gene1744	1.245e-201	640.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4DPBH@85009|Propionibacteriales	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
MMS3_k127_4267990_6	1313172.YM304_03920	1.145e-81	289.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CMZ7@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Polyprenyl synthetase	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS3_k127_4267990_2	1229780.BN381_110049	5.144e-157	509.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,3UW8P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS3_k127_4267990_5	1229780.BN381_110048	1.82e-86	294.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,3UWI1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
MMS3_k127_4267990_7	1229780.BN381_110032	2.902e-80	294.0	COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria,3UWIJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
MMS3_k127_4267990_1	1229780.BN381_110031	1.663e-166	544.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,3UW8F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Fumarate reductase flavoprotein C-term	nadB	GO:0008150,GO:0040007	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_4267990_17	1229780.BN381_640022	4.999e-37	156.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,3UXCR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Aspartate decarboxylase	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
MMS3_k127_4267990_11	1489678.RDMS_03645	6.428e-75	264.0	COG0414@1|root,COG0414@2|Bacteria,1WIB9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
MMS3_k127_4267990_14	1229780.BN381_110029	2.89e-57	209.0	COG5495@1|root,COG5495@2|Bacteria,2HGVN@201174|Actinobacteria,3UXIN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520
MMS3_k127_4267990_16	1229780.BN381_110028	4.542e-37	151.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,3UWU2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
MMS3_k127_4267990_18	1078020.KEK_07947	1.568e-27	115.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,239AF@1762|Mycobacteriaceae	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
MMS3_k127_4267990_15	1229780.BN381_110026	7.316e-44	174.0	2F3QB@1|root,33WH4@2|Bacteria,2H50W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4267990_12	1121381.JNIV01000102_gene2070	4.332e-68	241.0	COG0294@1|root,COG0294@2|Bacteria,1WJ2K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
MMS3_k127_4267990_9	1229780.BN381_110024	4.85e-80	280.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,3UWJV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
MMS3_k127_4267990_8	222534.KB893714_gene1574	4.025e-80	289.0	COG0037@1|root,COG0634@1|root,COG0037@2|Bacteria,COG0634@2|Bacteria,2GJR4@201174|Actinobacteria,4ERWN@85013|Frankiales	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
MMS3_k127_4267990_4	1229780.BN381_110020	2.343e-92	317.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,3UXC9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
MMS3_k127_4267990_19	525909.Afer_1917	3.143e-19	93.0	29XP9@1|root,30JEV@2|Bacteria,2HGER@201174|Actinobacteria,4CNCS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMS3_k127_4267990_10	525909.Afer_1918	6.216e-77	261.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CMZF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	sigR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_4267990_3	1449353.JQMQ01000004_gene6456	1.23e-143	467.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
MMS3_k127_4267990_13	101510.RHA1_ro04587	1.065e-58	232.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4FZKA@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_492874_16	351607.Acel_0402	7.798e-43	169.0	COG1520@1|root,COG1520@2|Bacteria,2I9FJ@201174|Actinobacteria,4EUHP@85013|Frankiales	201174|Actinobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
MMS3_k127_492874_1	235985.BBPN01000009_gene3843	7.073e-301	942.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,2NJXT@228398|Streptacidiphilus	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
MMS3_k127_492874_7	1869.MB27_12305	1.898e-91	310.0	COG4152@1|root,COG4152@2|Bacteria,2I2U6@201174|Actinobacteria,4DMD2@85008|Micromonosporales	201174|Actinobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	AAA_21,ABC_tran,DUF4162
MMS3_k127_492874_13	1089544.KB912942_gene1720	2.275e-53	199.0	COG1277@1|root,COG1277@2|Bacteria,2ID14@201174|Actinobacteria,4E7AP@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_492874_6	390989.JOEG01000004_gene3785	1.828e-93	317.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria,4D9HN@85008|Micromonosporales	201174|Actinobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_492874_12	235985.BBPN01000064_gene7393	1.74e-65	235.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,2NHHS@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
MMS3_k127_492874_10	1054860.KB913030_gene1305	3.493e-77	267.0	COG1028@1|root,COG1028@2|Bacteria,2I95F@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	ko:K14633	ko01057,ko01130,map01057,map01130	-	R09309,R09310	RC02484	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
MMS3_k127_492874_8	1961.JOAK01000010_gene6687	1.432e-89	311.0	COG2017@1|root,COG3265@1|root,COG2017@2|Bacteria,COG3265@2|Bacteria,2GJ0H@201174|Actinobacteria	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,SKI
MMS3_k127_492874_15	1229780.BN381_350126	1.234e-43	171.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria	201174|Actinobacteria	S	survival protein SurE	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
MMS3_k127_492874_18	929712.KI912613_gene1017	5.459e-31	128.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z4@201174|Actinobacteria,4CQHQ@84995|Rubrobacteria	84995|Rubrobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
MMS3_k127_492874_4	469371.Tbis_1278	2.641e-147	475.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4DX8D@85010|Pseudonocardiales	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_492874_17	196162.Noca_0302	5.068e-32	133.0	COG5517@1|root,COG5517@2|Bacteria,2IN5V@201174|Actinobacteria,4DQBF@85009|Propionibacteriales	201174|Actinobacteria	Q	SnoaL-like domain	baiE	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMS3_k127_492874_19	644283.Micau_5415	4.981e-29	121.0	COG1051@1|root,COG1051@2|Bacteria,2IHMP@201174|Actinobacteria,4DMA9@85008|Micromonosporales	201174|Actinobacteria	F	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_492874_2	1211815.CBYP010000067_gene115	1.18e-198	626.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4ETRJ@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE1_1	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_492874_14	1313301.AUGC01000013_gene1248	2.434e-48	185.0	COG1028@1|root,COG1028@2|Bacteria,4NEM6@976|Bacteroidetes	976|Bacteroidetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_492874_0	1463895.JODA01000019_gene7292	0.0	1289.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
MMS3_k127_492874_5	479433.Caci_2288	4.853e-129	436.0	COG2159@1|root,COG2159@2|Bacteria,2HG7W@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_492874_11	487521.OCU_33790	2.286e-66	239.0	COG4689@1|root,COG4689@2|Bacteria,2I8M2@201174|Actinobacteria,235NA@1762|Mycobacteriaceae	201174|Actinobacteria	Q	acetoacetate decarboxylase	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
MMS3_k127_492874_3	67257.JODR01000012_gene6018	4.868e-148	488.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_492874_9	1323361.JPOC01000022_gene3051	1.958e-77	269.0	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria,4G2MJ@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_493259_4	222534.KB893716_gene1819	5.901e-95	322.0	COG0778@1|root,COG0778@2|Bacteria,2I94X@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_493259_5	258533.BN977_00582	4.474e-73	258.0	COG0388@1|root,COG0388@2|Bacteria,2IDPB@201174|Actinobacteria,2377X@1762|Mycobacteriaceae	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
MMS3_k127_493259_2	450851.PHZ_c1001	3.968e-117	401.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,2KFVB@204458|Caulobacterales	204458|Caulobacterales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_493259_6	1394178.AWOO02000024_gene5605	3.545e-68	241.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_493259_9	765912.Thimo_3445	5.002e-19	96.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1WZQ1@135613|Chromatiales	135613|Chromatiales	F	other phosphorylase family 1	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_493259_8	234621.RER_39340	3.262e-26	124.0	COG4308@1|root,COG4308@2|Bacteria,2IID3@201174|Actinobacteria,4G9BK@85025|Nocardiaceae	201174|Actinobacteria	Q	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	LEH
MMS3_k127_493259_0	1313172.YM304_15700	2.155e-166	539.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CMUG@84992|Acidimicrobiia	201174|Actinobacteria	IQ	Protein synonym acyl-CoA synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS3_k127_493259_1	345341.KUTG_01890	7.898e-142	471.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,2HPPU@201174|Actinobacteria,4EB2Z@85010|Pseudonocardiales	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_493259_7	272623.L150205	7.463e-44	168.0	2CCI4@1|root,30BPJ@2|Bacteria,1VVCG@1239|Firmicutes,4HWDU@91061|Bacilli,1YCE4@1357|Lactococcus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_493259_3	649831.L083_4709	2.475e-104	346.0	COG2021@1|root,COG2021@2|Bacteria,2I3NA@201174|Actinobacteria,4DMU9@85008|Micromonosporales	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
MMS3_k127_563674_0	749414.SBI_04452	5.301e-258	803.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMS3_k127_563674_6	351607.Acel_1987	5.558e-61	226.0	COG3336@1|root,COG3336@2|Bacteria,2IKZR@201174|Actinobacteria,4EX8B@85013|Frankiales	201174|Actinobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG
MMS3_k127_563674_4	1121952.ATXT01000015_gene164	2.729e-91	317.0	COG0526@1|root,COG1999@1|root,COG0526@2|Bacteria,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	5.3.4.1	ko:K01829,ko:K07152	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	AhpC-TSA,SCO1-SenC,Thioredoxin,Thioredoxin_7
MMS3_k127_563674_5	543632.JOJL01000027_gene2891	4.477e-70	259.0	COG3832@1|root,COG3832@2|Bacteria,2GY9A@201174|Actinobacteria	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_563674_2	208444.JNYY01000001_gene5182	2.962e-132	431.0	COG0604@1|root,COG0604@2|Bacteria,2HHN3@201174|Actinobacteria,4E8RF@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
MMS3_k127_563674_1	1068978.AMETH_3058	1.088e-141	469.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4E2VY@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
MMS3_k127_563674_7	930169.B5T_04337	1.486e-46	179.0	COG3217@1|root,COG3217@2|Bacteria,1Q80Q@1224|Proteobacteria,1SFUE@1236|Gammaproteobacteria,1XPA1@135619|Oceanospirillales	135619|Oceanospirillales	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
MMS3_k127_563674_9	419947.MRA_1953	5.974e-23	103.0	2FDS3@1|root,345T0@2|Bacteria,2GUMT@201174|Actinobacteria,23BJN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
MMS3_k127_563674_8	1463887.KL589965_gene6164	3.628e-33	133.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
MMS3_k127_563674_3	710111.FraQA3DRAFT_0487	1.909e-120	403.0	COG2801@1|root,COG2801@2|Bacteria,2GNRT@201174|Actinobacteria,4EUFJ@85013|Frankiales	201174|Actinobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
MMS3_k127_563674_10	1173029.JH980292_gene1875	0.0004488	47.0	COG1403@1|root,COG1403@2|Bacteria,1G7VH@1117|Cyanobacteria,1HCI7@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_5
MMS3_k127_573362_6	298654.FraEuI1c_4236	4.187e-13	73.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_573362_4	457425.XNR_5389	2.724e-47	181.0	COG1309@1|root,COG1309@2|Bacteria,2GMCG@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_573362_7	1121877.JQKF01000016_gene135	1.573e-11	67.0	2BA7Z@1|root,323N2@2|Bacteria,2HH2A@201174|Actinobacteria,4CP2D@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_573362_5	47839.CCAU010000004_gene1015	6.937e-29	126.0	COG0300@1|root,COG0300@2|Bacteria,2GMI7@201174|Actinobacteria,2389H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_573362_1	644283.Micau_5335	3.073e-119	387.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4D9G8@85008|Micromonosporales	201174|Actinobacteria	C	Succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
MMS3_k127_573362_0	351607.Acel_1865	1.344e-279	871.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_573362_2	479433.Caci_0748	4.104e-96	322.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_573362_3	1156844.KB891831_gene4609	6.42e-65	238.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_574857_5	1283287.KB822577_gene3053	1.804e-34	138.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria,4DWJ6@85009|Propionibacteriales	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
MMS3_k127_574857_0	1214101.BN159_4715	9.721e-195	617.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria	201174|Actinobacteria	P	oxidoreductase	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C
MMS3_k127_574857_2	222534.KB893729_gene5672	9.862e-95	321.0	COG0580@1|root,COG0580@2|Bacteria,2GMG4@201174|Actinobacteria,4EV3E@85013|Frankiales	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	MIP
MMS3_k127_574857_3	298653.Franean1_0564	9.731e-49	187.0	COG0346@1|root,COG0346@2|Bacteria,2IFUM@201174|Actinobacteria,4EVK6@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_574857_6	566461.SSFG_07788	5.615e-27	114.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
MMS3_k127_574857_4	1380390.JIAT01000009_gene648	3.394e-39	149.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
MMS3_k127_574857_1	342113.DM82_6345	9.086e-162	525.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VPTU@28216|Betaproteobacteria,1KDJU@119060|Burkholderiaceae	28216|Betaproteobacteria	G	FGGY family of carbohydrate kinase, N-terminal domain protein	xylB2	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
MMS3_k127_629063_38	47839.CCAU010000002_gene2593	8.377e-17	83.0	COG5517@1|root,COG5517@2|Bacteria,2IHV4@201174|Actinobacteria,239DS@1762|Mycobacteriaceae	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMS3_k127_629063_36	479433.Caci_2615	5.365e-25	105.0	2BZ6B@1|root,336KR@2|Bacteria,2IQEV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_629063_10	1313172.YM304_33710	1.604e-128	415.0	COG0346@1|root,COG0346@2|Bacteria,2GM8H@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.25	ko:K16049	ko00984,ko01100,ko01120,ko01220,map00984,map01100,map01120,map01220	-	R04597	RC01610	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
MMS3_k127_629063_1	882083.SacmaDRAFT_3249	0.0	1065.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4E01Z@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	otsB1	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944	3.1.3.12,3.2.1.28	ko:K01087,ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010,R02778	RC00017,RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase
MMS3_k127_629063_18	882083.SacmaDRAFT_3250	1.32e-86	303.0	COG0637@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1877@2|Bacteria,2I2IT@201174|Actinobacteria,4EE80@85010|Pseudonocardiales	201174|Actinobacteria	G	Trehalose-phosphatase	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase,Trehalose_PPase
MMS3_k127_629063_3	557599.MKAN_07185	1.917e-196	623.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria,232S0@1762|Mycobacteriaceae	201174|Actinobacteria	I	lipid-transfer protein	ltp2	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
MMS3_k127_629063_30	557599.MKAN_07180	6.398e-49	182.0	COG2030@1|root,COG2030@2|Bacteria,2IHT0@201174|Actinobacteria,2392X@1762|Mycobacteriaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMS3_k127_629063_32	710686.Mycsm_02068	5.399e-46	175.0	COG1545@1|root,COG1545@2|Bacteria,2GM2A@201174|Actinobacteria,239A1@1762|Mycobacteriaceae	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_629063_24	1041522.MCOL_V217048	6.048e-67	243.0	COG2030@1|root,COG2030@2|Bacteria,2GN7T@201174|Actinobacteria,235VM@1762|Mycobacteriaceae	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
MMS3_k127_629063_7	1219035.NT2_11_00210	6.4e-141	463.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,2JZUE@204457|Sphingomonadales	204457|Sphingomonadales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
MMS3_k127_629063_42	557599.MKAN_15395	9.647e-13	81.0	COG1846@1|root,COG1846@2|Bacteria,2IHTR@201174|Actinobacteria,239I0@1762|Mycobacteriaceae	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
MMS3_k127_629063_45	1540221.JQNI01000002_gene855	3.811e-07	63.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
MMS3_k127_629063_41	1341646.CBMO010000108_gene4302	2.963e-13	77.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,2396B@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
MMS3_k127_629063_13	247156.NFA_33970	3.798e-120	398.0	COG1063@1|root,COG1063@2|Bacteria,2HVI2@201174|Actinobacteria,4FZYP@85025|Nocardiaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_629063_21	47839.CCAU010000005_gene296	2.065e-81	277.0	COG1028@1|root,COG1028@2|Bacteria,2I8G3@201174|Actinobacteria,232ID@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_629063_4	47839.CCAU010000005_gene295	3.795e-154	498.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria,235UZ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
MMS3_k127_629063_9	1194972.MVAC_11072	1.104e-132	437.0	2DB85@1|root,2Z7Q2@2|Bacteria,2GTBY@201174|Actinobacteria,232HI@1762|Mycobacteriaceae	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
MMS3_k127_629063_8	68199.JNZO01000006_gene2798	2.657e-135	440.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_629063_12	1123320.KB889662_gene1664	5.482e-124	406.0	28JIQ@1|root,2Z9BX@2|Bacteria,2IK2K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_629063_39	1122622.ATWJ01000009_gene3390	1.618e-16	87.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4FFVU@85021|Intrasporangiaceae	201174|Actinobacteria	P	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
MMS3_k127_629063_26	585531.HMPREF0063_12865	1.35e-60	215.0	COG0500@1|root,COG0500@2|Bacteria,2IMJ3@201174|Actinobacteria,4DR58@85009|Propionibacteriales	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_629063_14	1283283.ATXA01000001_gene591	4.203e-107	363.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
MMS3_k127_629063_15	2055.JNXA01000017_gene1607	4.623e-104	353.0	COG0657@1|root,COG0657@2|Bacteria,2H29U@201174|Actinobacteria,4GCF9@85026|Gordoniaceae	201174|Actinobacteria	I	Steryl acetyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMS3_k127_629063_2	1205680.CAKO01000029_gene5109	6.21e-219	690.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2U2E4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
MMS3_k127_629063_5	1209984.BN978_02644	1.47e-145	475.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,234WQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
MMS3_k127_629063_25	1229780.BN381_140035	1.922e-62	222.0	COG1136@1|root,COG1136@2|Bacteria,2I6MC@201174|Actinobacteria	201174|Actinobacteria	V	Product type t transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_629063_23	1229780.BN381_140036	8.573e-80	280.0	COG0577@1|root,COG0577@2|Bacteria,2HSGJ@201174|Actinobacteria,3UXNC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
MMS3_k127_629063_44	408672.NBCG_00751	3.97e-12	79.0	COG0778@1|root,COG0778@2|Bacteria,2I5BC@201174|Actinobacteria,4DSK6@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
MMS3_k127_629063_11	298655.KI912266_gene3184	3.848e-124	416.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GM3U@201174|Actinobacteria,4EUNB@85013|Frankiales	201174|Actinobacteria	S	AAA domain	-	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
MMS3_k127_629063_20	479431.Namu_4738	2.718e-84	285.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4ESHE@85013|Frankiales	201174|Actinobacteria	T	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07695	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
MMS3_k127_629063_19	351607.Acel_0516	2.033e-84	305.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4EXC4@85013|Frankiales	201174|Actinobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
MMS3_k127_629063_34	188626.HMPREF0321_0981	3.896e-37	151.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,1ZW9P@145357|Dermacoccaceae	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_629063_37	471852.Tcur_3812	1.481e-21	107.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4EPZ3@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_629063_43	1122611.KB904029_gene5346	1.688e-12	75.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EPN2@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_629063_17	1313172.YM304_28170	1.755e-91	312.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CMXH@84992|Acidimicrobiia	84992|Acidimicrobiia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
MMS3_k127_629063_31	28042.GU90_11250	4.576e-47	180.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DYY0@85010|Pseudonocardiales	201174|Actinobacteria	CK	Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
MMS3_k127_629063_6	1123023.JIAI01000001_gene5918	1.084e-144	467.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4E0VQ@85010|Pseudonocardiales	201174|Actinobacteria	S	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_629063_29	227882.SAV_1271	1.583e-50	190.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria	201174|Actinobacteria	K	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,Pyridox_ox_2
MMS3_k127_629063_35	1169152.AXVD01000003_gene4624	2.194e-28	133.0	COG0406@1|root,COG0494@1|root,COG0406@2|Bacteria,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4FVR6@85025|Nocardiaceae	201174|Actinobacteria	GL	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
MMS3_k127_629063_16	42256.RradSPS_0307	1.632e-100	357.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria	201174|Actinobacteria	S	CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
MMS3_k127_629063_40	1229780.BN381_90007	6.564e-16	87.0	2EKZY@1|root,33EPF@2|Bacteria,2H1IF@201174|Actinobacteria	201174|Actinobacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
MMS3_k127_629063_27	1172186.KB911481_gene5224	4.242e-58	211.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,232G5@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_629063_22	1033730.CAHG01000007_gene2633	5.27e-80	291.0	COG1984@1|root,COG2049@1|root,COG1984@2|Bacteria,COG2049@2|Bacteria,2GITH@201174|Actinobacteria,4DQVB@85009|Propionibacteriales	201174|Actinobacteria	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B,CT_C_D
MMS3_k127_629063_28	34007.IT40_02195	4.504e-52	193.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2TQUC@28211|Alphaproteobacteria,2PUYN@265|Paracoccus	28211|Alphaproteobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
MMS3_k127_629063_0	404589.Anae109_0406	0.0	1195.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YUG7@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD/H associated	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMS3_k127_629063_33	1229780.BN381_50095	6.809e-46	174.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria	201174|Actinobacteria	K	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMS3_k127_636472_2	1121877.JQKF01000024_gene2399	6.385e-169	539.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CMPX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
MMS3_k127_636472_18	1313172.YM304_20350	8.731e-29	132.0	COG0703@1|root,COG0703@2|Bacteria,2GRFW@201174|Actinobacteria,4CNCU@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
MMS3_k127_636472_6	1229780.BN381_50134	1.352e-105	356.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,3UWGT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829,ko:K16020	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R02412,R03083,R06592	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
MMS3_k127_636472_15	1229780.BN381_50135	8.2e-48	179.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,3UWWA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786,ko:K16021	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R03084,R06593	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
MMS3_k127_636472_11	717605.Theco_1992	3.858e-73	273.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,26QP9@186822|Paenibacillaceae	91061|Bacilli	E	Xaa-Pro dipeptidase	yqhT	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_636472_8	1121877.JQKF01000024_gene2404	2.05e-83	282.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CMZZ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
MMS3_k127_636472_20	1229780.BN381_50137	5.841e-22	100.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,3UWXH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
MMS3_k127_636472_12	1229780.BN381_50138	3.335e-65	228.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,3UWP5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
MMS3_k127_636472_7	471852.Tcur_3015	6.032e-99	342.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4EH29@85012|Streptosporangiales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMS3_k127_636472_3	1229780.BN381_50140	1.547e-142	466.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,3UWBY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
MMS3_k127_636472_5	1229780.BN381_50141	1.538e-124	409.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,3UWBX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
MMS3_k127_636472_0	1229780.BN381_50144	0.0	1452.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,3UW8D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
MMS3_k127_636472_9	1313172.YM304_20470	7.943e-81	299.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CN0R@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMS3_k127_636472_10	1288083.AUKR01000004_gene4077	5.032e-74	262.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
MMS3_k127_636472_17	525909.Afer_1696	7.913e-36	140.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4CN68@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_636472_16	1313172.YM304_20490	3.472e-39	154.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CN5V@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Guanylate kinase homologues.	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
MMS3_k127_636472_21	525909.Afer_1694	8.14e-19	91.0	COG1758@1|root,COG1758@2|Bacteria,2HG9P@201174|Actinobacteria,4CN82@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
MMS3_k127_636472_4	1229780.BN381_50149	2.886e-134	440.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,3UWCS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
MMS3_k127_636472_1	1048339.KB913029_gene3995	5.93e-170	542.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4ES7S@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
MMS3_k127_636472_19	1125863.JAFN01000001_gene2085	7.097e-28	131.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
MMS3_k127_636472_14	1229780.BN381_50154	1.027e-53	194.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,3UWS7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
MMS3_k127_636472_13	1313172.YM304_20570	4.872e-58	209.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CN6M@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Formyl transferase, C-terminal domain	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
MMS3_k127_71644_17	1229780.BN381_310068	1.187e-37	143.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,3UWR8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
MMS3_k127_71644_19	1313172.YM304_09890	9.613e-26	116.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
MMS3_k127_71644_6	1229780.BN381_310071	2.511e-99	334.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,3UWNK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
MMS3_k127_71644_5	1313172.YM304_09920	2.839e-113	374.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CMXZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
MMS3_k127_71644_2	479433.Caci_1300	5.039e-143	467.0	COG1696@1|root,COG1696@2|Bacteria,2GM6Z@201174|Actinobacteria	201174|Actinobacteria	M	Membrane bound O-acyl transferase MBOAT family protein	algI	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
MMS3_k127_71644_18	351607.Acel_0459	2.171e-34	147.0	COG2845@1|root,COG2845@2|Bacteria,2GU62@201174|Actinobacteria,4EWNP@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF459)	-	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459
MMS3_k127_71644_9	561175.KB894093_gene2983	1.302e-75	265.0	COG0730@1|root,COG0730@2|Bacteria,2GNW8@201174|Actinobacteria,4EGSD@85012|Streptosporangiales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_71644_10	1150398.JIBJ01000008_gene614	4.143e-65	238.0	COG5032@1|root,COG5032@2|Bacteria,2GME7@201174|Actinobacteria,1W9WA@1268|Micrococcaceae	201174|Actinobacteria	BDLTU	Phosphatidylinositol	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_71644_16	1121877.JQKF01000069_gene1260	1.172e-37	148.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,4CN9I@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
MMS3_k127_71644_11	1313172.YM304_10000	7.629e-62	222.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,4CNCR@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
MMS3_k127_71644_7	266117.Rxyl_2949	8.104e-85	291.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_71644_14	67257.JODR01000005_gene2136	4.989e-53	196.0	COG3231@1|root,COG3231@2|Bacteria,2HIED@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the aminoglycoside phosphotransferase family	-	-	2.7.1.95	ko:K00897	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
MMS3_k127_71644_3	710687.KI912270_gene6357	1.603e-140	481.0	COG1053@1|root,COG1053@2|Bacteria,2GKS3@201174|Actinobacteria,233WX@1762|Mycobacteriaceae	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	-	-	1.3.99.5	ko:K16051	ko00984,ko01120,map00984,map01120	-	R01834	RC00145	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
MMS3_k127_71644_20	1151061.CAJY01000025_gene3836	2.524e-25	112.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	paaI	GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
MMS3_k127_71644_1	1229780.BN381_310078	8.303e-155	497.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
MMS3_k127_71644_12	1229780.BN381_80351	1.549e-60	220.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria	201174|Actinobacteria	L	formamidopyrimidine-DNA glycosylase	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
MMS3_k127_71644_13	298653.Franean1_5635	8.861e-58	205.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4ESII@85013|Frankiales	201174|Actinobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS3_k127_71644_4	1229780.BN381_80340	3.046e-137	450.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,3UW8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
MMS3_k127_71644_8	1146883.BLASA_4228	2.748e-84	286.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4ESNR@85013|Frankiales	201174|Actinobacteria	S	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_71644_15	1123023.JIAI01000001_gene7344	2.508e-52	196.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4E0U1@85010|Pseudonocardiales	201174|Actinobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,Methyltransf_11
MMS3_k127_71644_0	631454.N177_1296	0.0	1106.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,1JNPN@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Aconitase family (aconitate hydratase)	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMS3_k127_766086_14	1121346.KB899817_gene3187	0.0003276	44.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,26TFI@186822|Paenibacillaceae	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
MMS3_k127_766086_11	710687.KI912270_gene3763	2.864e-50	183.0	COG3631@1|root,COG3631@2|Bacteria,2IJ87@201174|Actinobacteria,2397V@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMS3_k127_766086_9	1229780.BN381_290055	2.201e-54	211.0	COG4188@1|root,COG4188@2|Bacteria,2GZAJ@201174|Actinobacteria	201174|Actinobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
MMS3_k127_766086_0	58123.JOFJ01000012_gene5293	4.483e-306	953.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EFXA@85012|Streptosporangiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_766086_3	365528.KB891192_gene3574	4.904e-134	439.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	cyp108B4	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_766086_1	1160137.KB907307_gene1010	1.996e-152	489.0	COG0329@1|root,COG0329@2|Bacteria,2I92Q@201174|Actinobacteria	201174|Actinobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_766086_10	313589.JNB_10629	3.991e-53	201.0	COG1946@1|root,COG1946@2|Bacteria,2IA8W@201174|Actinobacteria,4FICJ@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
MMS3_k127_766086_7	298655.KI912266_gene4728	1.535e-106	355.0	COG2267@1|root,COG2267@2|Bacteria,2ID7Z@201174|Actinobacteria	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_766086_5	1194972.MVAC_10637	8.139e-114	376.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,234YE@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
MMS3_k127_766086_6	1386969.AWTB01000093_gene4357	4.038e-112	369.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,4GAX5@85026|Gordoniaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_766086_12	1283283.ATXA01000007_gene3789	8.737e-48	190.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMS3_k127_766086_2	298654.FraEuI1c_5065	2.839e-144	461.0	COG1024@1|root,COG1024@2|Bacteria,2GKNU@201174|Actinobacteria,4EVAR@85013|Frankiales	201174|Actinobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_766086_8	298655.KI912266_gene498	1.046e-72	256.0	COG1028@1|root,COG1028@2|Bacteria,2GNM4@201174|Actinobacteria,4EVVR@85013|Frankiales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.47	ko:K00034,ko:K00059	ko00030,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00030,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00572	R01520,R01521,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_766086_4	298655.KI912266_gene3058	3.795e-117	385.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.303,1.1.1.4	ko:K00004	ko00650,map00650	-	R02855,R02946,R10504	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_766086_13	365528.KB891192_gene3569	3.237e-34	134.0	COG2186@1|root,COG2186@2|Bacteria,2HU82@201174|Actinobacteria	201174|Actinobacteria	K	Regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS3_k127_802330_5	1229780.BN381_250088	6.695e-89	315.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
MMS3_k127_802330_12	1229780.BN381_450037	6.803e-47	172.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,3UWR3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
MMS3_k127_802330_8	1313172.YM304_38580	9.539e-64	226.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4CN0M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
MMS3_k127_802330_0	1394178.AWOO02000100_gene8296	5.062e-199	648.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EHI3@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_802330_1	1313172.YM304_34270	5.135e-105	348.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4CMXQ@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
MMS3_k127_802330_2	196490.AUEZ01000027_gene1741	5.733e-97	327.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,2U2R9@28211|Alphaproteobacteria,3JWD5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_802330_16	395494.Galf_2855	2.171e-30	132.0	COG0560@1|root,COG0560@2|Bacteria,1RKIX@1224|Proteobacteria,2VUZB@28216|Betaproteobacteria	28216|Betaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
MMS3_k127_802330_4	525909.Afer_1742	2.252e-95	340.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Amidase_2,Amidase_3,ChW,SpoIID
MMS3_k127_802330_11	644282.Deba_0452	1.836e-47	188.0	COG0438@1|root,COG0438@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_802330_14	525909.Afer_1744	1.32e-41	170.0	COG0438@1|root,COG0438@2|Bacteria,2HGNS@201174|Actinobacteria,4CNQP@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_802330_15	1121877.JQKF01000053_gene464	3.812e-33	145.0	COG0438@1|root,COG0438@2|Bacteria,2HGNS@201174|Actinobacteria,4CNQP@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_802330_10	1246995.AFR_04305	5.476e-63	245.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_802330_9	1280671.AUJH01000008_gene355	2.848e-63	232.0	COG0438@1|root,COG0438@2|Bacteria,1TQRV@1239|Firmicutes,24E7I@186801|Clostridia,4BYRD@830|Butyrivibrio	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
MMS3_k127_802330_13	246197.MXAN_4614	1.387e-42	174.0	COG0438@1|root,COG0438@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_802330_18	525909.Afer_1743	7.277e-16	89.0	2AQYZ@1|root,31G7P@2|Bacteria,2HGVJ@201174|Actinobacteria,4CNWG@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_802330_3	446466.Cfla_2372	9.627e-96	333.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
MMS3_k127_802330_6	525909.Afer_1748	1.986e-83	289.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4CNBI@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_802330_7	1121877.JQKF01000008_gene680	1.541e-81	284.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4CN0W@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_802330_17	1380347.JNII01000007_gene76	4.211e-21	96.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	garK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
MMS3_k127_858742_0	326424.FRAAL1777	1.075e-131	447.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMS3_k127_858742_2	525909.Afer_1580	6.337e-81	273.0	2CGIK@1|root,33UPP@2|Bacteria,2H4PB@201174|Actinobacteria,4CN1M@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_858742_3	1229780.BN381_330121	5.776e-51	189.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	-	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
MMS3_k127_858742_1	1116232.AHBF01000116_gene4432	5.775e-93	313.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_858742_4	326424.FRAAL6288	6.391e-39	151.0	COG1434@1|root,COG1434@2|Bacteria,2IMCB@201174|Actinobacteria	201174|Actinobacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
MMS3_k127_867840_25	525909.Afer_0248	5.468e-20	90.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CMST@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_867840_15	1146883.BLASA_1219	2.716e-45	186.0	COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS3_k127_867840_7	469371.Tbis_0080	8.31e-87	312.0	COG0484@1|root,COG0484@2|Bacteria,2GIXJ@201174|Actinobacteria,4DZEB@85010|Pseudonocardiales	201174|Actinobacteria	O	Replication initiator protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_867840_27	1146883.BLASA_1766	9.95e-15	78.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07075,ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_19,HTH_3,HTH_31
MMS3_k127_867840_21	1146883.BLASA_1767	7.044e-29	123.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria,4EX0H@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_867840_14	525909.Afer_1754	1.437e-48	183.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CN4T@84992|Acidimicrobiia	84992|Acidimicrobiia	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
MMS3_k127_867840_19	1229780.BN381_80116	8.498e-34	138.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,3UXRV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	JAB/MPN domain	mec	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
MMS3_k127_867840_22	1380356.JNIK01000013_gene4047	1.315e-26	111.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4ESZV@85013|Frankiales	201174|Actinobacteria	H	PFAM thiamineS protein	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS3_k127_867840_2	1313172.YM304_27740	1.911e-122	408.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CMZT@84992|Acidimicrobiia	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
MMS3_k127_867840_28	1121946.AUAX01000037_gene2067	2.89e-06	59.0	2EQEU@1|root,33I0T@2|Bacteria,2IMIW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
MMS3_k127_867840_17	479433.Caci_2585	5.959e-38	148.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria	201174|Actinobacteria	I	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
MMS3_k127_867840_3	1313172.YM304_27700	1.63e-99	338.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CMXE@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
MMS3_k127_867840_10	1313172.YM304_27690	6.157e-60	216.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CNBV@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
MMS3_k127_867840_24	1128421.JAGA01000001_gene2199	6.624e-21	106.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
MMS3_k127_867840_9	1123277.KB893228_gene2075	5.295e-75	268.0	COG0438@1|root,COG0438@2|Bacteria,4NK2Z@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_867840_8	1435356.Y013_15680	4.967e-83	287.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria,4FVAX@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_867840_13	1122247.C731_0984	8.712e-52	188.0	2AEPZ@1|root,314K8@2|Bacteria,2IEBE@201174|Actinobacteria,236M5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_867840_18	547163.BN979_04140	3.636e-36	157.0	COG0778@1|root,COG0778@2|Bacteria,2GKG5@201174|Actinobacteria,23EWU@1762|Mycobacteriaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_867840_23	298654.FraEuI1c_5263	3.466e-25	122.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
MMS3_k127_867840_16	298655.KI912266_gene5748	1.153e-42	160.0	COG2030@1|root,COG2030@2|Bacteria,2IGBP@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
MMS3_k127_867840_1	1313172.YM304_22430	2.061e-136	447.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	cyp279A2	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_867840_6	931627.MycrhDRAFT_5398	2.799e-89	304.0	COG0300@1|root,COG0300@2|Bacteria,2I9IM@201174|Actinobacteria,23F9W@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,adh_short
MMS3_k127_867840_20	1449068.JMLQ01000004_gene1440	4.31e-33	139.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4FXR3@85025|Nocardiaceae	201174|Actinobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
MMS3_k127_867840_26	1333998.M2A_2026	9.083e-20	97.0	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,2UGC3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
MMS3_k127_867840_0	298654.FraEuI1c_3065	5.813e-215	682.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
MMS3_k127_867840_12	1449069.JMLO01000002_gene4752	5.747e-55	208.0	COG0596@1|root,COG0596@2|Bacteria,2I8WB@201174|Actinobacteria,4G0AW@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_867840_4	106370.Francci3_2659	3.76e-95	329.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4ET1B@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_867840_5	1206739.BAGJ01000011_gene3338	2.108e-92	314.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4FV5H@85025|Nocardiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_867840_11	1313172.YM304_04880	1.916e-55	203.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4CN9A@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Glycerate kinase family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
MMS3_k127_869807_4	1121877.JQKF01000001_gene1342	2.733e-36	150.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,4CNRB@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
MMS3_k127_869807_0	1229780.BN381_80024	0.0	1455.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,3UW7W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
MMS3_k127_869807_1	469383.Cwoe_1925	4.122e-212	686.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4CR6R@84995|Rubrobacteria	201174|Actinobacteria	OT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_869807_2	1121877.JQKF01000001_gene1339	1.231e-163	550.0	COG0320@1|root,COG0321@1|root,COG0320@2|Bacteria,COG0321@2|Bacteria,2GKD4@201174|Actinobacteria,4CMR4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
MMS3_k127_869807_3	1121877.JQKF01000001_gene1338	2.21e-102	346.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4CMW0@84992|Acidimicrobiia	84992|Acidimicrobiia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_873047_12	525909.Afer_0743	7.312e-50	188.0	COG0438@1|root,COG0438@2|Bacteria,2GMEW@201174|Actinobacteria,4CNQH@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_873047_10	1304865.JAGF01000001_gene2609	2.367e-62	231.0	COG0438@1|root,COG0438@2|Bacteria,2GK9J@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_873047_7	1229780.BN381_10190	2.051e-88	300.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_873047_5	1229780.BN381_10192	4.792e-133	464.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,3UWUN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
MMS3_k127_873047_0	1121877.JQKF01000001_gene1297	3.024e-266	844.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CMRD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_873047_16	525909.Afer_1605	8.931e-27	123.0	COG1266@1|root,COG1266@2|Bacteria,2H0BD@201174|Actinobacteria,4CNBE@84992|Acidimicrobiia	84992|Acidimicrobiia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_873047_3	525909.Afer_1768	1.642e-160	532.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CMU2@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_873047_17	1449069.JMLO01000041_gene2881	5.266e-19	93.0	COG2835@1|root,COG2835@2|Bacteria,2GQID@201174|Actinobacteria,4G3YF@85025|Nocardiaceae	201174|Actinobacteria	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
MMS3_k127_873047_11	1229780.BN381_10202	1.409e-56	215.0	COG2222@1|root,COG2222@2|Bacteria,2HGM1@201174|Actinobacteria,3UXD9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS,bact-PGI_C
MMS3_k127_873047_2	1137268.AZXF01000044_gene11	8.809e-168	537.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4EGVJ@85012|Streptosporangiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_873047_1	1229780.BN381_400017	8.96e-179	567.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_873047_8	1229780.BN381_400016	2.353e-84	295.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_873047_14	500153.JOEK01000015_gene2745	1.016e-38	154.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
MMS3_k127_873047_13	929556.Solca_0685	1.327e-39	153.0	COG0681@1|root,COG0681@2|Bacteria,4NSIR@976|Bacteroidetes,1ITMV@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_873047_4	1068980.ARVW01000001_gene7666	4.656e-156	499.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DXE3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_873047_9	1122247.C731_1773	6.392e-80	278.0	COG2141@1|root,COG2141@2|Bacteria,2GJT1@201174|Actinobacteria,2330F@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_873047_6	471852.Tcur_3656	1.009e-124	418.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4EFPE@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
MMS3_k127_873047_15	258052.JNYV01000002_gene778	1.585e-38	151.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria,2M64U@2063|Kitasatospora	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_88605_2	1043205.AFYF01000078_gene1722	4.27e-91	316.0	COG2057@1|root,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,4FFD8@85021|Intrasporangiaceae	201174|Actinobacteria	I	Succinyl-CoA 3-ketoacid-CoA transferase	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
MMS3_k127_88605_1	479433.Caci_4892	3.581e-103	342.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria	201174|Actinobacteria	I	coenzyme A transferase	-	-	2.8.3.5,2.8.3.6	ko:K01028,ko:K01031	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
MMS3_k127_88605_4	258533.BN977_03935	5.118e-66	229.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,2374Z@1762|Mycobacteriaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_88605_3	258052.JNYV01000007_gene2906	1.029e-71	252.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria	201174|Actinobacteria	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS3_k127_88605_0	326424.FRAAL0380	9.105e-189	602.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4ERKB@85013|Frankiales	201174|Actinobacteria	E	Belongs to the group II decarboxylase family	gadB	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
MMS3_k127_88605_5	1209984.BN978_01470	1.057e-64	229.0	COG3832@1|root,COG3832@2|Bacteria,2IHY4@201174|Actinobacteria,239FM@1762|Mycobacteriaceae	201174|Actinobacteria	E	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_88605_10	246194.CHY_0598	3.773e-06	59.0	COG1943@1|root,COG1943@2|Bacteria,1V608@1239|Firmicutes,25CMT@186801|Clostridia,42H1Q@68295|Thermoanaerobacterales	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
MMS3_k127_88605_8	1120950.KB892756_gene6676	3.417e-10	72.0	2DT0G@1|root,33I5Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_88605_6	641491.DND132_2721	9.117e-27	123.0	COG1672@1|root,COG1672@2|Bacteria,1NMQH@1224|Proteobacteria,42YTJ@68525|delta/epsilon subdivisions,2WXAE@28221|Deltaproteobacteria,2MA4Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	-
MMS3_k127_88605_9	1292020.H483_0114595	8.257e-08	58.0	2AY0U@1|root,31Q2D@2|Bacteria,2IRI3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
MMS3_k127_88605_7	1179773.BN6_57060	4.487e-11	66.0	COG2963@1|root,COG2963@2|Bacteria,2GR4Q@201174|Actinobacteria,4EC9T@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
MMS3_k127_898066_13	365528.KB891245_gene6417	3.984e-31	128.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4EV5X@85013|Frankiales	201174|Actinobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_898066_2	1206735.BAGG01000265_gene6935	4.03e-164	529.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FX1Q@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_898066_9	1370120.AUWR01000088_gene2376	5.59e-74	263.0	COG1960@1|root,COG1960@2|Bacteria,2HQGI@201174|Actinobacteria,2335V@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
MMS3_k127_898066_4	426716.JOAJ01000002_gene2171	2.826e-150	509.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FX0R@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_898066_7	1101188.KI912156_gene4110	6.864e-118	415.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,1W7YE@1268|Micrococcaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_898066_8	1472716.KBK24_0103175	8.988e-111	378.0	COG1804@1|root,COG1804@2|Bacteria,1MWPB@1224|Proteobacteria,2W94E@28216|Betaproteobacteria,1K87Q@119060|Burkholderiaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_898066_3	1245471.PCA10_43630	1.705e-159	520.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1YJDT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_898066_0	365528.KB891262_gene5089	4.705e-185	589.0	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_898066_11	1380356.JNIK01000014_gene3328	2.655e-44	167.0	COG0431@1|root,COG0431@2|Bacteria,2GKM5@201174|Actinobacteria,4EVMT@85013|Frankiales	201174|Actinobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
MMS3_k127_898066_6	436229.JOEH01000008_gene4341	2.873e-119	415.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
MMS3_k127_898066_1	222534.KB893738_gene1273	1.73e-179	571.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4ES3N@85013|Frankiales	201174|Actinobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	lldD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iNJ661.Rv1872c	FMN_dh
MMS3_k127_898066_10	365528.KB891192_gene3568	4.526e-71	249.0	COG2128@1|root,COG2128@2|Bacteria,2II1N@201174|Actinobacteria,4EVJM@85013|Frankiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_898066_5	298653.Franean1_0586	2.784e-127	414.0	COG1063@1|root,COG1063@2|Bacteria,2IDE4@201174|Actinobacteria	201174|Actinobacteria	E	Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,Glu_dehyd_C
MMS3_k127_898066_12	47839.CCAU010000006_gene29	8.445e-33	128.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,235WD@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_915718_13	1229780.BN381_430047	7.949e-56	206.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,3UWJ4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMS3_k127_915718_10	448385.sce5042	4.452e-64	243.0	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,42S21@68525|delta/epsilon subdivisions,2WNRS@28221|Deltaproteobacteria,2YUP2@29|Myxococcales	28221|Deltaproteobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
MMS3_k127_915718_6	326424.FRAAL0672	1.283e-78	282.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4EREF@85013|Frankiales	201174|Actinobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_915718_5	298653.Franean1_6588	2.647e-79	272.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4ERG0@85013|Frankiales	201174|Actinobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_915718_7	446465.Bfae_15970	1.226e-74	259.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4FBA2@85020|Dermabacteraceae	201174|Actinobacteria	S	Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
MMS3_k127_915718_15	1246995.AFR_40545	1.3e-51	199.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4D8Z9@85008|Micromonosporales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMS3_k127_915718_4	656024.FsymDg_0692	3.394e-80	288.0	COG0392@1|root,COG0392@2|Bacteria,2GZ8W@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	2.3.2.3	ko:K07027,ko:K14205,ko:K20468	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
MMS3_k127_915718_19	1206731.BAGB01000044_gene5123	2.815e-13	80.0	COG3315@1|root,COG3315@2|Bacteria,2IF0D@201174|Actinobacteria,4FVUA@85025|Nocardiaceae	201174|Actinobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
MMS3_k127_915718_14	365528.KB891104_gene3769	5.306e-52	200.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4ET2P@85013|Frankiales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
MMS3_k127_915718_0	1229780.BN381_130089	1.736e-233	745.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,3UWBN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
MMS3_k127_915718_2	1229780.BN381_70018	2.399e-106	365.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,3UWBG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Cell cycle protein	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
MMS3_k127_915718_17	110319.CF8_3753	1.258e-42	158.0	COG2329@1|root,COG2329@2|Bacteria,2IM1Q@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
MMS3_k127_915718_20	525897.Dbac_0583	6.362e-11	76.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42TBU@68525|delta/epsilon subdivisions,2WP21@28221|Deltaproteobacteria,2MGK5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
MMS3_k127_915718_3	1121877.JQKF01000002_gene1765	1.714e-90	313.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4CN2U@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
MMS3_k127_915718_16	1313172.YM304_22030	3.012e-46	180.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
MMS3_k127_915718_12	1313172.YM304_20320	2.123e-56	211.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CN43@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
MMS3_k127_915718_11	525909.Afer_0953	2.742e-57	218.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CN7T@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
MMS3_k127_915718_18	1127134.NOCYR_3538	2.444e-24	112.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4G0KZ@85025|Nocardiaceae	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
MMS3_k127_915718_1	1229780.BN381_50129	1.528e-228	735.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,3UW8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
MMS3_k127_915718_8	1246995.AFR_04305	1.699e-71	270.0	COG0739@1|root,COG0739@2|Bacteria,2I589@201174|Actinobacteria,4DK5V@85008|Micromonosporales	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_915718_9	1449347.JQLN01000005_gene4400	1.45e-69	264.0	COG4934@1|root,COG4934@2|Bacteria,2H5BC@201174|Actinobacteria	201174|Actinobacteria	O	Pro-kumamolisin, activation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ
MMS3_k127_926631_2	1476876.JOJO01000001_gene7733	1.145e-119	396.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
MMS3_k127_926631_0	543632.JOJL01000018_gene9018	2.918e-136	445.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DAC8@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
MMS3_k127_926631_12	351607.Acel_0745	3.728e-71	254.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria,4ESWF@85013|Frankiales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
MMS3_k127_926631_7	211114.JOEF01000001_gene7037	7.814e-89	306.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4E020@85010|Pseudonocardiales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
MMS3_k127_926631_18	1120950.KB892796_gene2243	2.008e-43	167.0	COG1192@1|root,COG1192@2|Bacteria,2ICWE@201174|Actinobacteria,4DSPB@85009|Propionibacteriales	201174|Actinobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
MMS3_k127_926631_10	656024.FsymDg_3594	5.156e-80	303.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c_2,PAS_3,PAS_4,SpoIIE
MMS3_k127_926631_21	1304865.JAGF01000001_gene766	1.618e-21	98.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
MMS3_k127_926631_25	1291050.JAGE01000001_gene2083	7.445e-07	57.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,24Q6W@186801|Clostridia	186801|Clostridia	T	anti-sigma B factor	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
MMS3_k127_926631_13	298653.Franean1_0974	2.686e-63	231.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4ES7X@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_926631_5	28444.JODQ01000001_gene2485	5.469e-103	341.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria,4EK8D@85012|Streptosporangiales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_926631_9	1157637.KB892156_gene4080	1.919e-83	294.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_926631_1	1123320.KB889665_gene1469	2.634e-133	432.0	COG0451@1|root,COG0451@2|Bacteria,2I9DG@201174|Actinobacteria	201174|Actinobacteria	GM	Epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_926631_19	1283299.AUKG01000002_gene4742	3.015e-34	138.0	COG0454@1|root,COG0456@2|Bacteria,2GNNG@201174|Actinobacteria,4CQUQ@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_926631_22	396588.Tgr7_3298	4.687e-21	100.0	COG3655@1|root,COG3655@2|Bacteria,1QZZC@1224|Proteobacteria,1T4CQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMS3_k127_926631_8	1499967.BAYZ01000095_gene4182	1.899e-83	295.0	COG1486@1|root,COG1486@2|Bacteria,2NQP2@2323|unclassified Bacteria	2|Bacteria	G	Family 4 glycosyl hydrolase	lplD	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
MMS3_k127_926631_16	443255.SCLAV_5488	2.102e-58	218.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_926631_23	1120948.KB903243_gene2441	6.059e-20	104.0	COG1830@1|root,COG1830@2|Bacteria,2GKTN@201174|Actinobacteria,4DYYW@85010|Pseudonocardiales	201174|Actinobacteria	G	deoxyribose-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_926631_15	697281.Mahau_1378	1.402e-58	224.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,42FE3@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
MMS3_k127_926631_4	222534.KB893679_gene1077	8.537e-107	375.0	COG0410@1|root,COG0477@1|root,COG0410@2|Bacteria,COG2814@2|Bacteria,2IFX5@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,MFS_1
MMS3_k127_926631_6	1048339.KB913029_gene4038	6.572e-89	318.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
MMS3_k127_926631_17	222534.KB893716_gene1918	3.976e-56	214.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
MMS3_k127_926631_24	298655.KI912266_gene4547	3.812e-13	82.0	COG0683@1|root,COG0683@2|Bacteria,2HZXR@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMS3_k127_926631_11	767817.Desgi_3217	3.373e-74	259.0	COG4221@1|root,COG4221@2|Bacteria,1UIB4@1239|Firmicutes,25EG6@186801|Clostridia,265GT@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_926631_20	1155714.KB891993_gene5168	4.508e-23	114.0	COG5542@1|root,COG5542@2|Bacteria,2GJQF@201174|Actinobacteria	201174|Actinobacteria	NT	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_926631_14	580331.Thit_1725	1.179e-58	218.0	COG0412@1|root,COG0412@2|Bacteria,1TQQS@1239|Firmicutes,24DCW@186801|Clostridia,42FHF@68295|Thermoanaerobacterales	186801|Clostridia	Q	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,BAAT_C
MMS3_k127_926631_3	1464048.JNZS01000008_gene6190	1.012e-108	363.0	28KEA@1|root,2ZA0J@2|Bacteria,2I9YN@201174|Actinobacteria,4DCRZ@85008|Micromonosporales	201174|Actinobacteria	H	Sulfotransferase domain	-	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
MMS3_k127_968516_24	525909.Afer_0769	5.573e-64	242.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CMYJ@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMS3_k127_968516_35	1229780.BN381_80097	1.159e-16	93.0	COG2891@1|root,COG2891@2|Bacteria	2|Bacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
MMS3_k127_968516_32	525909.Afer_0767	2.097e-42	166.0	COG1792@1|root,COG1792@2|Bacteria,2HGG4@201174|Actinobacteria,4CNDF@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
MMS3_k127_968516_12	469383.Cwoe_2658	9.691e-152	486.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CP7J@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS3_k127_968516_29	1146883.BLASA_1542	2.317e-48	187.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4ESUM@85013|Frankiales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
MMS3_k127_968516_18	1313172.YM304_18330	3.932e-97	336.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CNAR@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
MMS3_k127_968516_3	479432.Sros_7289	5.889e-211	662.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4EI0M@85012|Streptosporangiales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
MMS3_k127_968516_19	525909.Afer_0762	5.344e-96	318.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CMUY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_968516_23	1313172.YM304_18300	3.089e-79	282.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CN55@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
MMS3_k127_968516_31	1077144.AGFF01000023_gene1383	3.025e-44	172.0	2DMG6@1|root,32RB5@2|Bacteria,2GMQI@201174|Actinobacteria	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
MMS3_k127_968516_36	68170.KL590498_gene6836	1.013e-14	89.0	2E479@1|root,32Z35@2|Bacteria,2GQXY@201174|Actinobacteria,4E6IX@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_968516_2	557599.MKAN_15370	1.57e-217	692.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,2353H@1762|Mycobacteriaceae	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_968516_16	1156844.KB891806_gene1735	6.487e-105	358.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_968516_38	1229487.AMYW01000007_gene3197	3.356e-06	49.0	2EMJ4@1|root,33F7P@2|Bacteria,4NYXT@976|Bacteroidetes,1I5IS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_968516_39	1048339.KB913029_gene2907	8.046e-06	56.0	2C4RB@1|root,2ZVRN@2|Bacteria,2HAZK@201174|Actinobacteria,4EWZ7@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_968516_21	298653.Franean1_0915	9.934e-92	308.0	COG1192@1|root,COG1192@2|Bacteria,2GNEQ@201174|Actinobacteria,4EUFG@85013|Frankiales	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMS3_k127_968516_9	1283283.ATXA01000001_gene1075	2.924e-158	515.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_968516_27	1123368.AUIS01000009_gene2443	5.781e-51	195.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMS3_k127_968516_4	525368.HMPREF0591_3178	3.66e-199	644.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,2351T@1762|Mycobacteriaceae	201174|Actinobacteria	P	Chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
MMS3_k127_968516_33	649831.L083_2760	7.61e-35	139.0	COG1846@1|root,COG1846@2|Bacteria,2IKZU@201174|Actinobacteria,4DF2P@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMS3_k127_968516_1	1449069.JMLO01000035_gene2669	7.314e-221	705.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4FZU3@85025|Nocardiaceae	201174|Actinobacteria	P	Voltage gated chloride channel	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
MMS3_k127_968516_22	557599.MKAN_19785	8.14e-86	293.0	COG0300@1|root,COG0300@2|Bacteria,2GMI7@201174|Actinobacteria,2389H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_968516_7	487521.OCU_43080	9.133e-161	518.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,23300@1762|Mycobacteriaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_968516_11	479431.Namu_2536	3.075e-153	492.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4ERUS@85013|Frankiales	201174|Actinobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
MMS3_k127_968516_14	710686.Mycsm_01044	2.402e-129	428.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,2363K@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the FGGY kinase family	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
MMS3_k127_968516_13	557599.MKAN_19810	1.039e-134	436.0	COG0111@1|root,COG0111@2|Bacteria,2GIZV@201174|Actinobacteria,236W4@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA2	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_968516_20	477641.MODMU_3554	6.419e-92	308.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4EUBC@85013|Frankiales	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
MMS3_k127_968516_28	525909.Afer_1561	1.608e-48	176.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,4CNU4@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
MMS3_k127_968516_26	83332.Rv0323c	3.331e-58	218.0	COG2120@1|root,COG2120@2|Bacteria,2IJ0C@201174|Actinobacteria,23BTH@1762|Mycobacteriaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_968516_34	525909.Afer_1936	5.673e-32	140.0	COG0500@1|root,COG0500@2|Bacteria,2I6VV@201174|Actinobacteria,4CNCW@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_968516_0	557599.MKAN_03230	6.407e-223	704.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,23CXI@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
MMS3_k127_968516_15	557599.MKAN_03165	3.402e-128	432.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,2348J@1762|Mycobacteriaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.39	ko:K00146,ko:K11947	ko00360,ko00624,ko00643,ko01100,ko01120,ko01220,map00360,map00624,map00643,map01100,map01120,map01220	-	R02536,R05649	RC00075,RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMS3_k127_968516_5	710686.Mycsm_00756	2.613e-178	566.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,235XV@1762|Mycobacteriaceae	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_968516_25	1463936.JOJI01000029_gene3267	1.399e-61	236.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS3_k127_968516_10	570268.ANBB01000002_gene218	1.241e-155	501.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4EGFJ@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_968516_30	1114964.L485_24100	3.376e-45	170.0	COG1545@1|root,COG1545@2|Bacteria,1PTPI@1224|Proteobacteria,2UVJV@28211|Alphaproteobacteria,2K6S6@204457|Sphingomonadales	204457|Sphingomonadales	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_968516_8	710421.Mycch_2953	6.399e-159	512.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,2341M@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_968516_17	1463858.JOHR01000001_gene6186	1.738e-102	354.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	2|Bacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C
MMS3_k127_968516_37	1101188.KI912155_gene3004	4.136e-10	73.0	2DB8V@1|root,2Z7SX@2|Bacteria,2IA72@201174|Actinobacteria	201174|Actinobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	1.1.99.3	ko:K06152	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	Gluconate_2-dh3
MMS3_k127_968516_6	1545915.JROG01000004_gene2194	2.768e-167	550.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K20D@204457|Sphingomonadales	204457|Sphingomonadales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_998736_23	644283.Micau_5222	7.402e-16	81.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4DAGY@85008|Micromonosporales	201174|Actinobacteria	C	dehydrogenase, E1 component	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
MMS3_k127_998736_21	284031.JNXD01000037_gene6309	2.314e-27	123.0	COG2267@1|root,COG2267@2|Bacteria,2I5RV@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMS3_k127_998736_15	105425.BBPL01000009_gene1392	1.288e-42	169.0	COG0697@1|root,COG0697@2|Bacteria,2GRXH@201174|Actinobacteria,2NFSH@228398|Streptacidiphilus	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_998736_6	351607.Acel_1116	5.123e-90	321.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4ESRC@85013|Frankiales	201174|Actinobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_998736_7	1123024.AUII01000003_gene3334	2.542e-84	291.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4DXT5@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport system, permease component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_998736_8	351607.Acel_1118	4.954e-84	290.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4ESGZ@85013|Frankiales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_998736_3	351607.Acel_1119	6.331e-133	432.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4ERFP@85013|Frankiales	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMS3_k127_998736_1	1120934.KB894419_gene2102	1.066e-140	463.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DXRP@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
MMS3_k127_998736_12	1229780.BN381_80160	9.841e-63	231.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,3UWTI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
MMS3_k127_998736_20	1283299.AUKG01000001_gene1443	4.259e-28	116.0	COG4274@1|root,COG4274@2|Bacteria,2HR6Q@201174|Actinobacteria,4CT2K@84995|Rubrobacteria	84995|Rubrobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_998736_4	1380390.JIAT01000012_gene3163	3.212e-113	382.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CRJZ@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K12429	-	-	-	-	ko00000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_998736_0	1156844.KB891831_gene4500	3.319e-161	544.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
MMS3_k127_998736_13	43354.JOIJ01000037_gene3226	9.699e-53	207.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4E1TB@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
MMS3_k127_998736_5	1502850.FG91_01688	6.856e-102	344.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,2K0GB@204457|Sphingomonadales	204457|Sphingomonadales	I	Glycerol-3-phosphate dehydrogenase	gpsA2	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
MMS3_k127_998736_17	1229780.BN381_80155	1.184e-39	158.0	COG1920@1|root,COG1920@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
MMS3_k127_998736_10	1121877.JQKF01000037_gene1811	7.8e-70	255.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria,4CNHM@84992|Acidimicrobiia	84992|Acidimicrobiia	U	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_998736_14	1380390.JIAT01000009_gene669	4.83e-43	174.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
MMS3_k127_998736_11	298654.FraEuI1c_3744	5.697e-68	256.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4ESHU@85013|Frankiales	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
MMS3_k127_998736_25	649638.Trad_1446	2.389e-07	62.0	COG3336@1|root,COG3336@2|Bacteria	2|Bacteria	G	cytochrome c oxidase	ctaG	-	-	ko:K02351,ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
MMS3_k127_998736_18	994479.GL877880_gene3837	4.534e-38	150.0	COG0030@1|root,COG0030@2|Bacteria,2H1TK@201174|Actinobacteria,4DXHF@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	ermE	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
MMS3_k127_998736_24	525909.Afer_0787	2.643e-14	80.0	2ANCW@1|root,31DBF@2|Bacteria,2HGY9@201174|Actinobacteria,4CNYH@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_998736_2	525909.Afer_0582	6.078e-137	451.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMQK@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
MMS3_k127_998736_16	1123023.JIAI01000003_gene3047	1.528e-41	169.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
MMS3_k127_998736_9	525909.Afer_1854	3.109e-74	253.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CMYS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
MMS3_k127_998736_22	369723.Strop_0742	1.574e-25	111.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4DF8Z@85008|Micromonosporales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_998736_19	1313172.YM304_10900	2.349e-36	140.0	COG0312@1|root,COG0312@2|Bacteria,2HGNU@201174|Actinobacteria,4CNQT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
## 1945 queries scanned
## Total time (seconds): 117.45995354652405
## Rate: 16.56 q/s