## Sat Nov 16 00:50:57 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin17/MMS_3_bin.77.fa -m mmseqs --itype genome -o MMS_3_bin.77 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/MMS_3_bin.77 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
MMS3_k127_1008065_2	240015.ACP_2661	1.562e-95	322.0	COG3677@1|root,COG3677@2|Bacteria,3Y5PF@57723|Acidobacteria,2JK2Q@204432|Acidobacteriia	204432|Acidobacteriia	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
MMS3_k127_1008065_1	1121405.dsmv_3246	1.524e-120	412.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
MMS3_k127_1008065_3	1395571.TMS3_0107095	4.588e-95	321.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Methyl-transferase	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
MMS3_k127_1008065_0	1395571.TMS3_0107090	8.04e-161	519.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	sumf2	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
MMS3_k127_1008065_5	1150626.PHAMO_230074	8.135e-17	84.0	COG2022@1|root,COG2104@1|root,COG2022@2|Bacteria,COG2104@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2JPMG@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
MMS3_k127_1008065_4	338966.Ppro_3475	1.728e-89	298.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,43TNT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
MMS3_k127_1100358_11	316067.Geob_2303	4.556e-15	87.0	COG0392@1|root,COG0392@2|Bacteria,1RCGI@1224|Proteobacteria,42RDB@68525|delta/epsilon subdivisions,2WMU8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
MMS3_k127_1100358_3	1267535.KB906767_gene4148	1.472e-117	390.0	COG0463@1|root,COG0463@2|Bacteria,3Y30V@57723|Acidobacteria,2JIJ8@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1100358_8	682795.AciX8_1433	9.136e-51	196.0	COG3394@1|root,COG3394@2|Bacteria,3Y441@57723|Acidobacteria,2JI4E@204432|Acidobacteriia	204432|Acidobacteriia	G	YdjC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
MMS3_k127_1100358_9	204669.Acid345_1405	3.499e-42	168.0	COG0457@1|root,COG0457@2|Bacteria,3Y7Q5@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
MMS3_k127_1100358_0	58123.JOFJ01000001_gene2985	0.0	1894.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4EGYC@85012|Streptosporangiales	201174|Actinobacteria	E	GXGXG motif	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
MMS3_k127_1100358_2	671143.DAMO_0866	7.345e-222	703.0	COG0493@1|root,COG0493@2|Bacteria,2NNUI@2323|unclassified Bacteria	2|Bacteria	E	Flavin containing amine oxidoreductase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
MMS3_k127_1100358_1	1242864.D187_004920	1.662e-230	724.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
MMS3_k127_1100358_13	1429851.X548_13335	1.293e-05	56.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
MMS3_k127_1100358_10	1121939.L861_22850	1.076e-35	145.0	COG0382@1|root,COG2249@1|root,COG0382@2|Bacteria,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,1S3UT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	NADPH-quinone reductase (modulator of drug activity B)	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2,UbiA
MMS3_k127_1100358_6	204669.Acid345_3688	2.786e-65	233.0	COG0106@1|root,COG0106@2|Bacteria,3Y4TG@57723|Acidobacteria,2JKDT@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMS3_k127_1100358_5	204669.Acid345_2162	7.691e-85	294.0	COG1462@1|root,COG1462@2|Bacteria,3Y3KF@57723|Acidobacteria	57723|Acidobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
MMS3_k127_1100358_4	240015.ACP_2336	3.321e-85	291.0	COG0107@1|root,COG0107@2|Bacteria,3Y2MG@57723|Acidobacteria,2JI7H@204432|Acidobacteriia	204432|Acidobacteriia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMS3_k127_1100358_7	240015.ACP_2337	3.063e-60	215.0	COG0118@1|root,COG0118@2|Bacteria,3Y5DZ@57723|Acidobacteria,2JKDU@204432|Acidobacteriia	204432|Acidobacteriia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMS3_k127_1100358_12	204669.Acid345_3685	2.015e-13	70.0	COG0131@1|root,COG0131@2|Bacteria,3Y3DU@57723|Acidobacteria,2JHMN@204432|Acidobacteriia	204432|Acidobacteriia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
MMS3_k127_1102140_22	472759.Nhal_1120	1.235e-86	298.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
MMS3_k127_1102140_37	768671.ThimaDRAFT_1687	2.5e-40	159.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1WXMB@135613|Chromatiales	135613|Chromatiales	M	Soluble lytic murein transglycosylase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
MMS3_k127_1102140_48	1123354.AUDR01000018_gene1140	1.76e-15	80.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,1KTBG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein S20	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
MMS3_k127_1102140_47	243231.GSU2207	1.129e-18	100.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42SNR@68525|delta/epsilon subdivisions,2WP96@28221|Deltaproteobacteria,43TIV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
MMS3_k127_1102140_42	1047013.AQSP01000135_gene1588	2.035e-27	124.0	COG2980@1|root,COG2980@2|Bacteria	2|Bacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
MMS3_k127_1102140_0	269799.Gmet_2300	2.103e-308	967.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,43TD1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	leucyl-tRNA aminoacylation	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
MMS3_k127_1102140_25	483219.LILAB_16730	1.399e-83	290.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2YUVF@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
MMS3_k127_1102140_2	234267.Acid_7252	4.872e-258	830.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1102140_46	1416759.AYMR01000024_gene2597	7.636e-19	101.0	COG1846@1|root,COG1846@2|Bacteria,2HPHY@201174|Actinobacteria,4FS87@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMS3_k127_1102140_16	204669.Acid345_4575	2.318e-113	385.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,3Y65Z@57723|Acidobacteria,2JM5S@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_1102140_15	204669.Acid345_4576	3.217e-114	394.0	COG1131@1|root,COG1131@2|Bacteria,3Y3PY@57723|Acidobacteria,2JIQU@204432|Acidobacteriia	204432|Acidobacteriia	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1102140_33	204669.Acid345_4577	4.603e-50	192.0	COG1566@1|root,COG1566@2|Bacteria,3Y6U1@57723|Acidobacteria,2JKUF@204432|Acidobacteriia	204432|Acidobacteriia	V	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_D23
MMS3_k127_1102140_18	926550.CLDAP_29660	1.841e-95	324.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
MMS3_k127_1102140_9	1464048.JNZS01000012_gene3467	2.206e-179	572.0	COG1032@1|root,COG1032@2|Bacteria,2GZU1@201174|Actinobacteria,4DC30@85008|Micromonosporales	201174|Actinobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1102140_39	472759.Nhal_2071	3.462e-34	146.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SEZZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
MMS3_k127_1102140_5	204669.Acid345_3065	8.965e-198	630.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
MMS3_k127_1102140_17	1382359.JIAL01000001_gene1740	7.958e-102	340.0	COG2025@1|root,COG2025@2|Bacteria,3Y4SJ@57723|Acidobacteria,2JP3Y@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
MMS3_k127_1102140_23	204669.Acid345_3697	2.45e-86	292.0	COG2086@1|root,COG2086@2|Bacteria,3Y2PD@57723|Acidobacteria,2JK7K@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
MMS3_k127_1102140_7	234267.Acid_1167	4.723e-186	590.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMS3_k127_1102140_41	204669.Acid345_4505	4.668e-28	114.0	COG0236@1|root,COG0236@2|Bacteria,3Y54V@57723|Acidobacteria,2JJPU@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
MMS3_k127_1102140_27	903818.KI912268_gene2024	3.124e-81	276.0	COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria	57723|Acidobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_1102140_21	243231.GSU1602	1.092e-91	326.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
MMS3_k127_1102140_19	204669.Acid345_4145	8.675e-94	331.0	COG0416@1|root,COG0416@2|Bacteria,3Y3MM@57723|Acidobacteria,2JHTJ@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
MMS3_k127_1102140_45	1382359.JIAL01000001_gene525	2.004e-20	93.0	COG0333@1|root,COG0333@2|Bacteria,3Y5HY@57723|Acidobacteria,2JJZ9@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
MMS3_k127_1102140_43	644966.Tmar_0943	7.722e-25	111.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia	186801|Clostridia	S	acr, cog1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
MMS3_k127_1102140_14	289376.THEYE_A0539	3.975e-119	392.0	COG0232@1|root,COG0232@2|Bacteria	2|Bacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
MMS3_k127_1102140_12	1121430.JMLG01000003_gene532	1.216e-131	432.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
MMS3_k127_1102140_49	234267.Acid_1162	2.867e-14	76.0	COG1923@1|root,COG1923@2|Bacteria,3Y59T@57723|Acidobacteria	57723|Acidobacteria	S	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
MMS3_k127_1102140_28	1267533.KB906734_gene4208	5.184e-73	257.0	COG0324@1|root,COG0324@2|Bacteria,3Y3CE@57723|Acidobacteria,2JICH@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
MMS3_k127_1102140_50	1382359.JIAL01000001_gene1780	6.437e-11	73.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria,2JHKT@204432|Acidobacteriia	204432|Acidobacteriia	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
MMS3_k127_1102140_31	518766.Rmar_2332	1.321e-61	221.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1FJ8B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMS3_k127_1102140_34	717606.PaecuDRAFT_3274	1.022e-48	181.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,26RDA@186822|Paenibacillaceae	91061|Bacilli	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
MMS3_k127_1102140_29	234267.Acid_1310	4.22e-69	256.0	COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria	57723|Acidobacteria	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
MMS3_k127_1102140_32	880072.Desac_1408	6.795e-61	229.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2WIRS@28221|Deltaproteobacteria,2MRK6@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMS3_k127_1102140_13	667014.Thein_1033	3.326e-127	421.0	COG1060@1|root,COG1060@2|Bacteria,2GH1Z@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
MMS3_k127_1102140_44	1121405.dsmv_0650	2.244e-21	104.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2WJ4C@28221|Deltaproteobacteria,2MIGE@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3391	Radical_SAM
MMS3_k127_1102140_11	269799.Gmet_2187	6.715e-138	453.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WJX5@28221|Deltaproteobacteria,43U6C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mycolic acid cyclopropane synthetase	cfa1	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	iAF987.Gmet_2187	CMAS
MMS3_k127_1102140_38	522306.CAP2UW1_0011	3.359e-37	149.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
MMS3_k127_1102140_10	1121033.AUCF01000006_gene4283	8.604e-149	486.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2TQJN@28211|Alphaproteobacteria,2JPG5@204441|Rhodospirillales	204441|Rhodospirillales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
MMS3_k127_1102140_1	102129.Lepto7375DRAFT_0116	5.142e-308	974.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1H8QW@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
MMS3_k127_1102140_30	886293.Sinac_3851	1.188e-62	222.0	COG1926@1|root,COG1926@2|Bacteria,2J36S@203682|Planctomycetes	203682|Planctomycetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
MMS3_k127_1102140_36	344747.PM8797T_30312	2.442e-41	160.0	COG0589@1|root,COG0589@2|Bacteria,2J042@203682|Planctomycetes	203682|Planctomycetes	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_1102140_35	1434929.X946_2442	1.179e-41	170.0	COG1371@1|root,COG1371@2|Bacteria,1N301@1224|Proteobacteria,2VVPE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
MMS3_k127_1102140_4	713586.KB900536_gene819	1.593e-209	668.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WW29@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0027	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
MMS3_k127_1102140_8	644966.Tmar_0286	2.524e-185	601.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WCD6@538999|Clostridiales incertae sedis	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMS3_k127_1102140_3	1254432.SCE1572_36715	9.707e-223	704.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2YX9H@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase beta thumb	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
MMS3_k127_1102140_20	1347086.CCBA010000031_gene968	5.492e-92	329.0	COG2202@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,PAS_9
MMS3_k127_1102140_40	1168034.FH5T_18400	2.662e-33	137.0	COG2606@1|root,COG2606@2|Bacteria,4P3TW@976|Bacteroidetes,2FXVH@200643|Bacteroidia	976|Bacteroidetes	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
MMS3_k127_1102140_51	1173024.KI912151_gene2116	1.389e-08	62.0	COG0071@1|root,COG0071@2|Bacteria,1G4BC@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
MMS3_k127_1102140_6	234267.Acid_3945	2.164e-188	600.0	COG0043@1|root,COG0043@2|Bacteria,3Y3BY@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
MMS3_k127_1102140_26	1499967.BAYZ01000057_gene4676	3.71e-82	291.0	COG0673@1|root,COG0673@2|Bacteria,2NNUQ@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA
MMS3_k127_1102140_24	1267533.KB906734_gene4091	6.136e-86	292.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria,2JIMV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
MMS3_k127_1167564_7	452637.Oter_3540	1.869e-101	340.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,46W3S@74201|Verrucomicrobia,3K7PR@414999|Opitutae	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
MMS3_k127_1167564_1	316274.Haur_0105	3.76e-209	667.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,3750X@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
MMS3_k127_1167564_14	1120951.AUBG01000001_gene887	1.107e-44	169.0	COG1845@1|root,COG1845@2|Bacteria,4NUH6@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
MMS3_k127_1167564_12	344747.PM8797T_16243	2.774e-48	184.0	COG3336@1|root,COG3336@2|Bacteria	2|Bacteria	G	cytochrome c oxidase	-	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
MMS3_k127_1167564_21	1120951.AUBG01000001_gene885	4.253e-06	54.0	2CIBM@1|root,33NHZ@2|Bacteria,4NYXH@976|Bacteroidetes,1IA6J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
MMS3_k127_1167564_11	344747.PM8797T_16253	1.152e-59	213.0	COG0723@1|root,COG0723@2|Bacteria,2J13H@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Rieske 2Fe-2S domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
MMS3_k127_1167564_3	452637.Oter_3544	2.025e-176	573.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B,Cytochrome_CBB3
MMS3_k127_1167564_0	1123060.JONP01000009_gene2102	1.397e-235	739.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria,2JRMB@204441|Rhodospirillales	204441|Rhodospirillales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
MMS3_k127_1167564_8	234267.Acid_7579	8.888e-83	289.0	COG0738@1|root,COG0738@2|Bacteria,3Y92Y@57723|Acidobacteria	57723|Acidobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1167564_5	1282360.ABAC460_22805	5.356e-147	479.0	COG0520@1|root,COG0520@2|Bacteria,1NRXE@1224|Proteobacteria	1224|Proteobacteria	E	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Methyltransf_25
MMS3_k127_1167564_13	452637.Oter_1480	4.636e-46	181.0	COG1451@1|root,COG1451@2|Bacteria,46VW6@74201|Verrucomicrobia,3K7I9@414999|Opitutae	414999|Opitutae	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
MMS3_k127_1167564_18	234267.Acid_5547	6.131e-35	147.0	COG0392@1|root,COG0392@2|Bacteria,3Y7S6@57723|Acidobacteria	57723|Acidobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
MMS3_k127_1167564_6	1173024.KI912149_gene5224	1.39e-132	435.0	COG0438@1|root,COG0438@2|Bacteria,1G1J6@1117|Cyanobacteria,1JGXJ@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferase 4-like	sqdX	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1167564_2	197221.22294119	5.515e-199	626.0	COG0451@1|root,COG0451@2|Bacteria,1G0TM@1117|Cyanobacteria	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	sqdB	-	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	iJN678.sqdB	Epimerase
MMS3_k127_1167564_10	1267533.KB906734_gene4110	6.293e-81	284.0	COG0613@1|root,COG0613@2|Bacteria,3Y451@57723|Acidobacteria,2JI8Q@204432|Acidobacteriia	204432|Acidobacteriia	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1167564_4	240015.ACP_1359	8.931e-151	485.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	57723|Acidobacteria	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
MMS3_k127_1167564_15	234267.Acid_4434	2.093e-39	163.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMS3_k127_1167564_20	1200792.AKYF01000011_gene3656	2.787e-08	65.0	COG0346@1|root,COG0346@2|Bacteria,1V5HJ@1239|Firmicutes,4HMUV@91061|Bacilli,275R3@186822|Paenibacillaceae	91061|Bacilli	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
MMS3_k127_1167564_9	1005048.CFU_1088	5.57e-82	291.0	COG0644@1|root,COG0644@2|Bacteria,1PQI2@1224|Proteobacteria,2VUCT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
MMS3_k127_1167564_17	1122143.AUEG01000015_gene1848	6.899e-37	154.0	COG1216@1|root,COG1216@2|Bacteria,1V7WV@1239|Firmicutes,4HJ3H@91061|Bacilli,27HUD@186828|Carnobacteriaceae	91061|Bacilli	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1167564_16	713587.THITH_12650	3.134e-37	155.0	COG0189@1|root,COG0189@2|Bacteria,1P1RY@1224|Proteobacteria	1224|Proteobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1167564_19	582899.Hden_0829	7.162e-24	105.0	COG2940@1|root,COG2940@2|Bacteria,1N3VM@1224|Proteobacteria,2UDY0@28211|Alphaproteobacteria,3N93Y@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
MMS3_k127_117217_10	469381.Dpep_1062	1.24e-32	130.0	COG0128@1|root,COG0128@2|Bacteria,3TAG4@508458|Synergistetes	508458|Synergistetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
MMS3_k127_117217_12	638303.Thal_0550	1.185e-28	126.0	COG0703@1|root,COG0703@2|Bacteria,2G46N@200783|Aquificae	200783|Aquificae	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
MMS3_k127_117217_6	234267.Acid_0953	1.11e-62	229.0	COG0639@1|root,COG0639@2|Bacteria,3Y3U2@57723|Acidobacteria	57723|Acidobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_117217_7	502025.Hoch_3361	2.999e-50	186.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,430WM@68525|delta/epsilon subdivisions,2WVP8@28221|Deltaproteobacteria,2Z2VW@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
MMS3_k127_117217_5	502025.Hoch_3360	3.091e-64	227.0	COG2386@1|root,COG2386@2|Bacteria,1QF23@1224|Proteobacteria,42RAM@68525|delta/epsilon subdivisions,2WMS1@28221|Deltaproteobacteria,2YVDV@29|Myxococcales	28221|Deltaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
MMS3_k127_117217_8	1125863.JAFN01000001_gene3012	1.341e-48	185.0	COG1131@1|root,COG1131@2|Bacteria,1RGM1@1224|Proteobacteria,43ADE@68525|delta/epsilon subdivisions,2X5TA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
MMS3_k127_117217_21	391625.PPSIR1_01192	2.655e-06	57.0	2ANI1@1|root,31DGW@2|Bacteria,1QARK@1224|Proteobacteria,43E3E@68525|delta/epsilon subdivisions,2WZKG@28221|Deltaproteobacteria,2Z2BA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_117217_0	502025.Hoch_3351	6.299e-233	747.0	COG1138@1|root,COG3088@1|root,COG1138@2|Bacteria,COG3088@2|Bacteria,1MUQS@1224|Proteobacteria,42P4Q@68525|delta/epsilon subdivisions,2WK5G@28221|Deltaproteobacteria,2YU4N@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
MMS3_k127_117217_17	525904.Tter_1506	1.331e-10	68.0	COG2332@1|root,COG2332@2|Bacteria,2NQ2A@2323|unclassified Bacteria	2|Bacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
MMS3_k127_117217_9	861299.J421_3871	1.343e-40	164.0	COG0424@1|root,COG0424@2|Bacteria,1ZTP7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
MMS3_k127_117217_2	1198114.AciX9_1021	8.26e-148	479.0	COG0183@1|root,COG0183@2|Bacteria,3Y3SQ@57723|Acidobacteria,2JHU2@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_117217_3	235909.GK3395	2.508e-113	372.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1WFG8@129337|Geobacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS3_k127_117217_15	489825.LYNGBM3L_22580	6.379e-13	78.0	COG1988@1|root,COG1988@2|Bacteria,1G9P5@1117|Cyanobacteria,1HG2W@1150|Oscillatoriales	1117|Cyanobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
MMS3_k127_117217_1	1267533.KB906733_gene3429	4.849e-164	522.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
MMS3_k127_117217_14	748727.CLJU_c32240	5.587e-20	98.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,36JV0@31979|Clostridiaceae	186801|Clostridia	I	Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
MMS3_k127_117217_16	1198114.AciX9_2169	9.089e-11	74.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
MMS3_k127_117217_11	439493.PB7211_294	3.2e-29	132.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,2TXEY@28211|Alphaproteobacteria,4BTEZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Big_3_5
MMS3_k127_117217_20	1198114.AciX9_2169	9.672e-09	67.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
MMS3_k127_117217_13	439493.PB7211_294	3.351e-27	125.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,2TXEY@28211|Alphaproteobacteria,4BTEZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Big_3_5
MMS3_k127_117217_19	1198114.AciX9_2169	2.206e-09	69.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
MMS3_k127_117217_4	1250232.JQNJ01000001_gene498	2.594e-112	376.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1174834_5	1267535.KB906767_gene66	3.528e-194	615.0	COG1008@1|root,COG1008@2|Bacteria,3Y3VX@57723|Acidobacteria	2|Bacteria	C	Proton-conducting membrane transporter	nuoM	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iSDY_1059.SDY_2473	Proton_antipo_M
MMS3_k127_1174834_9	1267535.KB906767_gene67	5.296e-151	496.0	COG1007@1|root,COG1007@2|Bacteria,3Y3PV@57723|Acidobacteria,2JIT3@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
MMS3_k127_1174834_36	204669.Acid345_3014	8.953e-24	112.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
MMS3_k127_1174834_13	335543.Sfum_3112	1.09e-114	395.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MSIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
MMS3_k127_1174834_1	234267.Acid_7252	6.222e-268	861.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1174834_11	767434.Fraau_3023	4.818e-123	439.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1X4RX@135614|Xanthomonadales	135614|Xanthomonadales	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
MMS3_k127_1174834_14	1183438.GKIL_4354	8.36e-113	395.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1174834_16	521719.ATXQ01000003_gene2186	4.184e-100	333.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1YECG@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
MMS3_k127_1174834_43	1123058.KB894226_gene41	0.0009923	43.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1HXRT@117743|Flavobacteriia	976|Bacteroidetes	P	membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
MMS3_k127_1174834_22	1163409.UUA_15288	1.265e-68	241.0	COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,1RQ8S@1236|Gammaproteobacteria,1X6KF@135614|Xanthomonadales	135614|Xanthomonadales	O	Peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMS3_k127_1174834_38	1121926.AXWO01000005_gene407	2.013e-16	90.0	2DRM1@1|root,33C8J@2|Bacteria,2IJ2W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1174834_33	1352941.M877_22255	1.261e-40	154.0	COG3877@1|root,COG3877@2|Bacteria,2IJTS@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
MMS3_k127_1174834_8	1340493.JNIF01000003_gene1964	1.903e-152	493.0	COG1915@1|root,COG1915@2|Bacteria	2|Bacteria	E	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf,Saccharop_dh_N
MMS3_k127_1174834_32	269799.Gmet_2150	3.726e-41	168.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria,43UFV@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamR	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_1174834_4	1267535.KB906767_gene4458	8.926e-197	636.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
MMS3_k127_1174834_37	1396418.BATQ01000180_gene3033	3.167e-19	99.0	COG1295@1|root,COG1295@2|Bacteria,46SUZ@74201|Verrucomicrobia,2IV0S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
MMS3_k127_1174834_25	1267534.KB906754_gene2972	8.043e-65	239.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
MMS3_k127_1174834_23	1125863.JAFN01000001_gene565	3.435e-68	249.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
MMS3_k127_1174834_21	682795.AciX8_3483	2.383e-69	244.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
MMS3_k127_1174834_12	1125863.JAFN01000001_gene2253	1.754e-121	406.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_1174834_2	1382306.JNIM01000001_gene2570	1.855e-250	783.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMS3_k127_1174834_19	1128421.JAGA01000002_gene1141	6.99e-80	279.0	COG1024@1|root,COG1024@2|Bacteria,2NR3A@2323|unclassified Bacteria	2|Bacteria	I	Enoyl-CoA hydratase/isomerase	atuE	-	4.2.1.18,4.2.1.57	ko:K13766,ko:K13779	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R02085,R03493	RC00941,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_1174834_7	1382306.JNIM01000001_gene2567	5.227e-161	522.0	COG4770@1|root,COG4770@2|Bacteria,2GBIE@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
MMS3_k127_1174834_39	399739.Pmen_2030	1.249e-14	80.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1YE9N@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Biotin carboxylase, N-terminal domain	mccA	-	6.4.1.4,6.4.1.5	ko:K01968,ko:K13777	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R03494,R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
MMS3_k127_1174834_15	1234664.AMRO01000076_gene2488	3.337e-106	354.0	COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,1WE8S@129337|Geobacillus	91061|Bacilli	E	HMGL-like	yngG	GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
MMS3_k127_1174834_26	661478.OP10G_4076	5.573e-56	218.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
MMS3_k127_1174834_40	1552123.EP57_10315	1.522e-09	68.0	COG1670@1|root,COG1670@2|Bacteria,1V5TN@1239|Firmicutes,4HIF4@91061|Bacilli,26N4X@186820|Listeriaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_1174834_29	886293.Sinac_4049	1.465e-52	192.0	COG0783@1|root,COG0783@2|Bacteria,2IZJP@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
MMS3_k127_1174834_10	1128421.JAGA01000002_gene335	3.959e-146	475.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_1174834_18	2340.JV46_19800	3.067e-80	279.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,1RRQ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Helix-hairpin-helix domain	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_5,HHH_8
MMS3_k127_1174834_20	479434.Sthe_2697	2.291e-77	267.0	COG1656@1|root,COG1977@1|root,COG1656@2|Bacteria,COG1977@2|Bacteria,2G6GZ@200795|Chloroflexi,27Y8I@189775|Thermomicrobia	189775|Thermomicrobia	H	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
MMS3_k127_1174834_17	909663.KI867150_gene2720	3.573e-89	335.0	COG0535@1|root,COG0535@2|Bacteria,1Q6NI@1224|Proteobacteria,433FI@68525|delta/epsilon subdivisions,2WXJT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_1174834_0	234267.Acid_0922	0.0	1422.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,3Y7VB@57723|Acidobacteria	57723|Acidobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
MMS3_k127_1174834_6	234267.Acid_0921	1.685e-181	587.0	COG3581@1|root,COG3581@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1174834_30	1267535.KB906767_gene514	1.458e-49	183.0	COG0586@1|root,COG0586@2|Bacteria,3Y7W0@57723|Acidobacteria	57723|Acidobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_1174834_24	1379270.AUXF01000004_gene3199	1.287e-65	237.0	COG3342@1|root,COG3342@2|Bacteria,1ZUFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
MMS3_k127_1174834_3	1379270.AUXF01000001_gene2513	7.493e-204	653.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	2|Bacteria	J	Amidase	gatA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS3_k127_1174834_28	1047013.AQSP01000131_gene1841	2.03e-53	215.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_1174834_34	1439940.BAY1663_01462	5.882e-26	114.0	COG3620@1|root,COG3620@2|Bacteria,1N78J@1224|Proteobacteria,1SB0T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
MMS3_k127_1174834_31	1158292.JPOE01000006_gene3933	3.442e-45	167.0	COG4683@1|root,COG4683@2|Bacteria,1MZIY@1224|Proteobacteria,2VWKG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
MMS3_k127_1174834_27	1116472.MGMO_101c00010	3.941e-54	202.0	2F43J@1|root,33WV2@2|Bacteria,1NW3P@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1174834_41	1397696.KK211189_gene2556	3.519e-07	59.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1174834_35	880072.Desac_0749	6.227e-25	111.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria,2MQQY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
MMS3_k127_1177306_2	401053.AciPR4_4079	1.854e-64	237.0	COG0477@1|root,COG2814@2|Bacteria,3Y9D8@57723|Acidobacteria,2JP6Z@204432|Acidobacteriia	204432|Acidobacteriia	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	-
MMS3_k127_1177306_3	1267533.KB906737_gene1984	6.81e-60	217.0	COG4270@1|root,COG4270@2|Bacteria,3Y68W@57723|Acidobacteria	57723|Acidobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
MMS3_k127_1177306_1	59196.RICGR_1016	3.283e-141	462.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria,1JFG2@118969|Legionellales	118969|Legionellales	P	Natural resistance-associated macrophage protein	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
MMS3_k127_1177306_0	234267.Acid_5922	1.607e-168	547.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_1177306_4	1356852.N008_03795	1.53e-33	134.0	2E6DR@1|root,3311A@2|Bacteria,4NWX0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1190017_48	1185876.BN8_05111	5.571e-33	138.0	COG0790@1|root,COG0790@2|Bacteria,4PKKJ@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
MMS3_k127_1190017_65	391616.OA238_c17290	9.606e-06	57.0	COG4567@1|root,COG4567@2|Bacteria,1RKVN@1224|Proteobacteria,2UARS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
MMS3_k127_1190017_20	240015.ACP_2205	1.077e-99	348.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_1190017_19	357808.RoseRS_1744	7.707e-104	357.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,375MK@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMS3_k127_1190017_24	861299.J421_4277	1.027e-80	279.0	COG0276@1|root,COG0276@2|Bacteria,1ZTW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
MMS3_k127_1190017_9	1254432.SCE1572_46550	2.784e-130	424.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2YTSB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
MMS3_k127_1190017_58	1380346.JNIH01000018_gene5254	6.363e-15	81.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mprA	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1190017_56	234267.Acid_2620	2.371e-18	98.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1190017_47	1108045.GORHZ_137_00230	1.067e-36	149.0	COG3629@1|root,COG3629@2|Bacteria,2IBMM@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
MMS3_k127_1190017_67	1304876.AZVC01000002_gene681	0.0003676	45.0	2C7N6@1|root,2ZFXQ@2|Bacteria,2GQSQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
MMS3_k127_1190017_41	1379698.RBG1_1C00001G0886	1.694e-44	175.0	COG1686@1|root,COG1686@2|Bacteria,2NPJT@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S11 family	pbpG	GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564	3.4.16.4	ko:K01286,ko:K07258,ko:K07262	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	iECO103_1326.ECO103_2610,iYL1228.KPN_02573	Peptidase_S11
MMS3_k127_1190017_55	316067.Geob_1646	6.057e-22	106.0	COG3058@1|root,COG3058@2|Bacteria,1NK06@1224|Proteobacteria,42VNJ@68525|delta/epsilon subdivisions,2WS9J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Necessary for formate dehydrogenase activity	fdhE	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
MMS3_k127_1190017_7	290397.Adeh_0135	7.849e-138	456.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
MMS3_k127_1190017_44	1232410.KI421412_gene415	1.964e-39	151.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,43UZN@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
MMS3_k127_1190017_11	671143.DAMO_1612	6.704e-124	405.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9,4.3.1.9	ko:K00384,ko:K03671,ko:K22345	ko00030,ko00450,ko04621,ko05418,map00030,map00450,map04621,map05418	-	R01544,R02016,R03596,R09372	RC00013,RC00544,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913,iPC815.YPO1374	Pyr_redox_2
MMS3_k127_1190017_17	1382359.JIAL01000001_gene2117	1.595e-110	367.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria,2JHKV@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
MMS3_k127_1190017_13	383372.Rcas_4262	1.152e-113	378.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,3751V@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
MMS3_k127_1190017_52	204669.Acid345_1716	4.037e-27	119.0	COG1664@1|root,COG1664@2|Bacteria,3Y49V@57723|Acidobacteria,2JJ4E@204432|Acidobacteriia	57723|Acidobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMS3_k127_1190017_62	1340493.JNIF01000003_gene1766	2.196e-09	67.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
MMS3_k127_1190017_33	518766.Rmar_1448	4.836e-64	229.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1FIS0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
MMS3_k127_1190017_4	1379698.RBG1_1C00001G0527	8.647e-163	521.0	COG1960@1|root,COG1960@2|Bacteria,2NNXA@2323|unclassified Bacteria	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1190017_10	234267.Acid_7175	2.161e-126	421.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria	57723|Acidobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
MMS3_k127_1190017_45	292459.STH75	3.52e-39	159.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
MMS3_k127_1190017_18	1121430.JMLG01000009_gene476	3.575e-106	360.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,2606G@186807|Peptococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
MMS3_k127_1190017_61	1123226.KB899293_gene116	6.626e-11	75.0	COG1361@1|root,COG2931@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1VX9E@1239|Firmicutes,4HIIK@91061|Bacilli,26SBE@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Lectin_legB,SLH,fn3
MMS3_k127_1190017_50	1499967.BAYZ01000084_gene3991	8.137e-30	125.0	COG0558@1|root,COG0558@2|Bacteria,2NRJN@2323|unclassified Bacteria	2|Bacteria	I	CDP-alcohol phosphatidyltransferase	MA20_28295	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_1190017_31	234267.Acid_5500	2.259e-70	252.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	HemolysinCabind,Pro_isomerase
MMS3_k127_1190017_66	270374.MELB17_03612	3.766e-05	55.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,1S2YT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	yfhR	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
MMS3_k127_1190017_63	324602.Caur_3714	7.223e-09	59.0	2A42D@1|root,30SM6@2|Bacteria,2GAFV@200795|Chloroflexi,375ZW@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1190017_28	63737.Npun_F0753	1.071e-73	256.0	COG4106@1|root,COG4106@2|Bacteria,1G7X0@1117|Cyanobacteria,1HR55@1161|Nostocales	1117|Cyanobacteria	S	Methyltransferase domain	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
MMS3_k127_1190017_21	886379.AEWI01000001_gene1794	6.002e-94	319.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,2FNAN@200643|Bacteroidia,3XKQT@558415|Marinilabiliaceae	976|Bacteroidetes	L	impB/mucB/samB family C-terminal domain	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
MMS3_k127_1190017_0	985867.AEWF01000004_gene108	2.786e-257	804.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,47EU8@766|Rickettsiales	766|Rickettsiales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	abcT1	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
MMS3_k127_1190017_5	1499967.BAYZ01000057_gene4733	1.268e-149	478.0	COG0451@1|root,COG0451@2|Bacteria,2NP15@2323|unclassified Bacteria	2|Bacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	rfbB	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
MMS3_k127_1190017_8	1499967.BAYZ01000017_gene6221	1.603e-130	440.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
MMS3_k127_1190017_15	1499967.BAYZ01000055_gene4868	9.367e-112	373.0	COG0438@1|root,COG0438@2|Bacteria,2NP1P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	wcnD	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1190017_22	204669.Acid345_1265	1.293e-90	310.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria,2JJTZ@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1190017_43	926550.CLDAP_27810	1.644e-42	166.0	COG1216@1|root,COG1216@2|Bacteria,2G8DR@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
MMS3_k127_1190017_42	1128421.JAGA01000002_gene28	6.409e-43	180.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1190017_40	222534.KB893683_gene1180	1.954e-48	189.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,4ERHJ@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_1190017_2	1144275.COCOR_00988	3.115e-170	546.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_1190017_12	713587.THITH_00175	2.464e-116	384.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1WWNR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS3_k127_1190017_27	237368.SCABRO_00372	1.839e-75	265.0	COG1215@1|root,COG1215@2|Bacteria,2IXXE@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1190017_6	314345.SPV1_07951	4.715e-149	507.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria	1224|Proteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_1190017_35	648996.Theam_1402	1.003e-57	207.0	COG0194@1|root,COG0194@2|Bacteria,2G3ZQ@200783|Aquificae	200783|Aquificae	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
MMS3_k127_1190017_14	204669.Acid345_3776	6.309e-113	379.0	COG0452@1|root,COG0452@2|Bacteria,3Y2QJ@57723|Acidobacteria,2JIK5@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
MMS3_k127_1190017_29	671143.DAMO_2419	1.19e-73	255.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_1190017_3	502025.Hoch_5549	2.883e-165	550.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2YU5P@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
MMS3_k127_1190017_32	1499967.BAYZ01000068_gene1971	3.952e-69	252.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
MMS3_k127_1190017_49	204669.Acid345_1185	3.67e-32	127.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U4@57723|Acidobacteria,2JP27@204432|Acidobacteriia	204432|Acidobacteriia	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMS3_k127_1190017_16	562970.Btus_1769	1.101e-110	374.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
MMS3_k127_1190017_57	1267535.KB906767_gene3605	4.474e-16	89.0	COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria	57723|Acidobacteria	K	regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMS3_k127_1190017_36	1131814.JAFO01000001_gene2560	2.779e-56	204.0	COG0500@1|root,COG0500@2|Bacteria,1R4KQ@1224|Proteobacteria,2U35H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1190017_51	1306947.ARQD01000001_gene904	3.366e-29	127.0	2E8G5@1|root,332UG@2|Bacteria	1306947.ARQD01000001_gene904|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1190017_34	316067.Geob_2601	4.328e-59	217.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,437BB@68525|delta/epsilon subdivisions,2X2G7@28221|Deltaproteobacteria,43V98@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
MMS3_k127_1190017_60	344747.PM8797T_14971	5.983e-13	72.0	COG1278@1|root,COG1278@2|Bacteria,2J13Y@203682|Planctomycetes	203682|Planctomycetes	K	COG1278 Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_1190017_46	673862.BABL1_267	6.466e-38	163.0	COG0275@1|root,COG0275@2|Bacteria	2|Bacteria	J	rRNA processing	noeI	-	-	ko:K21402	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_21,rRNA_methylase
MMS3_k127_1190017_54	449447.MAE_55250	8.893e-24	114.0	COG1216@1|root,COG1216@2|Bacteria,1G705@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,RgpF
MMS3_k127_1190017_30	304371.MCP_1933	1.964e-71	254.0	arCOG07799@1|root,arCOG07799@2157|Archaea	2157|Archaea	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2,Glycos_transf_2
MMS3_k127_1190017_37	765952.PUV_00260	2.779e-56	204.0	2BRIW@1|root,32KHW@2|Bacteria	2|Bacteria	S	Glycosyltransferase family 6	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_6
MMS3_k127_1190017_25	765952.PUV_00250	8.255e-79	273.0	28SKE@1|root,2ZEWR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
MMS3_k127_1190017_38	1313172.YM304_35300	9.417e-53	202.0	COG0463@1|root,COG0463@2|Bacteria,2HGY7@201174|Actinobacteria,4CNYB@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1190017_1	1267535.KB906767_gene2263	2.206e-202	635.0	COG0535@1|root,COG0535@2|Bacteria,3Y2JV@57723|Acidobacteria,2JI93@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
MMS3_k127_1190017_39	1267535.KB906767_gene2264	3.808e-49	179.0	29E6W@1|root,3014W@2|Bacteria,3Y4JR@57723|Acidobacteria,2JJ83@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1210253_8	1144275.COCOR_02357	1.925e-94	322.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	ko:K16416	ko01052,map01052	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
MMS3_k127_1210253_11	909613.UO65_5304	0.0003165	54.0	2B0K8@1|root,31SXX@2|Bacteria,2GRC0@201174|Actinobacteria,4ED70@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1210253_1	582515.KR51_00012630	0.0	1206.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
MMS3_k127_1210253_0	1469607.KK073768_gene2203	0.0	1268.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HIST@1161|Nostocales	1117|Cyanobacteria	Q	acyl transferase domain	-	-	-	ko:K16129	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Aminotran_3,Bac_luciferase,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_12,PP-binding,ketoacyl-synt
MMS3_k127_1210253_6	221288.JH992901_gene3908	9.901e-183	646.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJRC@1189|Stigonemataceae	1117|Cyanobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,PP-binding
MMS3_k127_1210253_2	756067.MicvaDRAFT_2506	0.0	1049.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H9T8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
MMS3_k127_1210253_9	1463920.JOGB01000005_gene1963	2.406e-60	219.0	28N16@1|root,2Z9CB@2|Bacteria,2I812@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1210253_10	760154.Sulba_0744	1.115e-41	160.0	COG3597@1|root,COG3597@2|Bacteria,1MZA4@1224|Proteobacteria,43BFR@68525|delta/epsilon subdivisions,2YT87@29547|Epsilonproteobacteria	1224|Proteobacteria	S	protein associated with GTPases	-	-	-	-	-	-	-	-	-	-	-	-	DUF697
MMS3_k127_1210253_7	1379270.AUXF01000001_gene1910	2.023e-95	321.0	COG0179@1|root,COG0179@2|Bacteria,1ZTIG@142182|Gemmatimonadetes	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
MMS3_k127_1210253_4	251229.Chro_4146	1.643e-210	683.0	COG0642@1|root,COG0784@1|root,COG3614@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3614@2|Bacteria,1G09B@1117|Cyanobacteria,3VJ2S@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
MMS3_k127_1210253_5	251221.35211765	2.138e-199	648.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1210253_3	1267535.KB906767_gene1400	6.43e-243	778.0	COG0577@1|root,COG0577@2|Bacteria,3Y3V2@57723|Acidobacteria,2JM9M@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1240504_7	880073.Calab_0960	1.137e-37	145.0	COG0241@1|root,COG0241@2|Bacteria,2NPK4@2323|unclassified Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033692,GO:0034200,GO:0034637,GO:0034645,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046872,GO:0046914,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	3.1.3.15,3.1.3.82,3.1.3.83,4.2.1.19,6.3.2.10	ko:K01089,ko:K01929,ko:K02843,ko:K03273	ko00300,ko00340,ko00540,ko00550,ko01100,ko01110,ko01230,ko01502,map00300,map00340,map00540,map00550,map01100,map01110,map01230,map01502	M00026,M00064,M00080	R03013,R03457,R04573,R04617,R05647,R09771	RC00017,RC00064,RC00141,RC00932	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko01011	-	GT9	iB21_1397.B21_00198,iEC55989_1330.EC55989_0198,iECBD_1354.ECBD_3418,iECB_1328.ECB_00199,iECD_1391.ECD_00199,iECIAI1_1343.ECIAI1_0202,iECO103_1326.ECO103_0200,iECSE_1348.ECSE_0202,iETEC_1333.ETEC_0196,iEcHS_1320.EcHS_A0204,iEcolC_1368.EcolC_3459	HAD_2,Hydrolase_like
MMS3_k127_1240504_4	234267.Acid_6381	7.966e-64	231.0	COG0859@1|root,COG0859@2|Bacteria,3Y6NF@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMS3_k127_1240504_6	1125863.JAFN01000001_gene527	9.719e-44	181.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMS3_k127_1240504_5	1232428.CAVO010000064_gene283	4.983e-49	189.0	COG1663@1|root,COG1663@2|Bacteria,1TWGA@1239|Firmicutes,4H97G@909932|Negativicutes	909932|Negativicutes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glycos_transf_N,LpxK
MMS3_k127_1240504_2	671143.DAMO_1644	6.949e-98	336.0	COG1519@1|root,COG1519@2|Bacteria,2NP5A@2323|unclassified Bacteria	2|Bacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
MMS3_k127_1240504_0	1009370.ALO_11594	4.978e-149	479.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H298@909932|Negativicutes	909932|Negativicutes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
MMS3_k127_1240504_1	1121918.ARWE01000001_gene1723	1.134e-131	433.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,43S14@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
MMS3_k127_1240504_3	378806.STAUR_5234	3.614e-80	275.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,2YU88@29|Myxococcales	28221|Deltaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
MMS3_k127_1240504_8	1382359.JIAL01000001_gene843	1.053e-17	87.0	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria,2JJVA@204432|Acidobacteriia	204432|Acidobacteriia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
MMS3_k127_1245788_2	861299.J421_2469	1.405e-91	311.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
MMS3_k127_1245788_5	671143.DAMO_1446	6.854e-56	207.0	COG0500@1|root,COG2226@2|Bacteria,2NPUA@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	pmtA	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
MMS3_k127_1245788_7	243231.GSU0196	2.451e-28	124.0	COG2050@1|root,COG2050@2|Bacteria,1NHB0@1224|Proteobacteria,42XCC@68525|delta/epsilon subdivisions,2WTEP@28221|Deltaproteobacteria,43UMX@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_1245788_4	1232410.KI421412_gene406	1.724e-74	276.0	COG1193@1|root,COG1193@2|Bacteria,1QYV7@1224|Proteobacteria	1224|Proteobacteria	L	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1245788_0	880072.Desac_1748	9.723e-241	775.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MREW@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMS3_k127_1245788_3	644966.Tmar_0092	1.68e-81	285.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WCTC@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
MMS3_k127_1245788_8	1206720.BAFQ01000293_gene6346	3.176e-28	132.0	COG2020@1|root,COG2020@2|Bacteria,2GN9N@201174|Actinobacteria,4FZCX@85025|Nocardiaceae	201174|Actinobacteria	O	NnrU protein	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU
MMS3_k127_1245788_1	1131269.AQVV01000012_gene2582	8.047e-109	389.0	COG0304@1|root,COG0304@2|Bacteria	2|Bacteria	I	3-oxoacyl-[acyl-carrier-protein] synthase activity	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMS3_k127_1245788_6	861299.J421_4181	7.474e-45	179.0	COG0644@1|root,COG0644@2|Bacteria,1ZTEM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glucose inhibited division protein A	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
MMS3_k127_1245788_9	66869.JNXG01000018_gene4385	6.005e-25	111.0	COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria,41AR5@629295|Streptomyces griseus group	201174|Actinobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	srsB	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
MMS3_k127_1277333_1	317655.Sala_2616	2.879e-165	528.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,2K3BR@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
MMS3_k127_1277333_5	1149133.ppKF707_2048	9.743e-07	60.0	COG1357@1|root,COG1357@2|Bacteria,1MWKD@1224|Proteobacteria,1RY8C@1236|Gammaproteobacteria,1YHKP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Pentapeptide
MMS3_k127_1277333_4	1367847.JCM7686_pAMI4p243	2.853e-07	55.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1RITM@1224|Proteobacteria,2V4XA@28211|Alphaproteobacteria,2PY1B@265|Paracoccus	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
MMS3_k127_1277333_3	234267.Acid_0524	2.281e-45	174.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
MMS3_k127_1277333_2	861299.J421_2861	7.941e-88	301.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1ZTKD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
MMS3_k127_1277333_0	1283287.KB822578_gene2446	9.783e-217	682.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4DPQG@85009|Propionibacteriales	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMS3_k127_1277333_6	870187.Thini_4297	1.581e-05	48.0	COG3597@1|root,COG3597@2|Bacteria,1MZA4@1224|Proteobacteria,1S95Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	DUF697
MMS3_k127_1287718_17	1267533.KB906735_gene4448	1.417e-69	252.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
MMS3_k127_1287718_18	404589.Anae109_3016	2.132e-64	233.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMS3_k127_1287718_29	1121116.KB894766_gene315	4.78e-26	112.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,4AE4Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMS3_k127_1287718_21	1184267.A11Q_79	7.788e-51	190.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1287718_31	671143.DAMO_2924	9.476e-17	84.0	2CBGA@1|root,33A66@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1287718_19	204669.Acid345_0496	6.082e-56	212.0	COG3568@1|root,COG3568@2|Bacteria,3Y4HM@57723|Acidobacteria,2JKST@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
MMS3_k127_1287718_28	234267.Acid_5381	5.454e-31	128.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
MMS3_k127_1287718_34	1278073.MYSTI_03804	7.793e-07	59.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMS3_k127_1287718_23	525904.Tter_0756	5.087e-41	161.0	COG1595@1|root,COG1595@2|Bacteria,2NPHU@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1287718_7	1047013.AQSP01000115_gene336	7.636e-163	559.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2,TolB_N
MMS3_k127_1287718_22	867903.ThesuDRAFT_02082	3.003e-41	164.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3WDHI@538999|Clostridiales incertae sedis	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_1287718_36	118173.KB235914_gene1203	0.0006751	52.0	COG3577@1|root,COG3577@2|Bacteria,1G044@1117|Cyanobacteria,1HAAQ@1150|Oscillatoriales	1117|Cyanobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
MMS3_k127_1287718_37	357808.RoseRS_3925	0.0006751	52.0	COG0457@1|root,COG0457@2|Bacteria,2GBDY@200795|Chloroflexi,375DC@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
MMS3_k127_1287718_24	240015.ACP_0948	4.422e-39	147.0	COG1146@1|root,COG1146@2|Bacteria,3Y59N@57723|Acidobacteria,2JJRG@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4
MMS3_k127_1287718_32	562970.Btus_2616	3.924e-14	84.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,278TK@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	kipR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
MMS3_k127_1287718_30	903818.KI912268_gene3191	1.27e-25	113.0	COG4911@1|root,COG4911@2|Bacteria,3Y4VB@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
MMS3_k127_1287718_13	767817.Desgi_0471	4.079e-101	338.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,260DQ@186807|Peptococcaceae	186801|Clostridia	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS3_k127_1287718_6	1379698.RBG1_1C00001G0805	1.851e-192	618.0	COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_1287718_12	1382306.JNIM01000001_gene268	8.47e-106	349.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS3_k127_1287718_16	525904.Tter_0760	1.147e-78	271.0	COG2220@1|root,COG2220@2|Bacteria,2NPQC@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Lactamase_B_2,Lactamase_B_3
MMS3_k127_1287718_3	1254432.SCE1572_07645	1.831e-207	669.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,437U1@68525|delta/epsilon subdivisions,2X33K@28221|Deltaproteobacteria,2YU2K@29|Myxococcales	28221|Deltaproteobacteria	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
MMS3_k127_1287718_2	1254432.SCE1572_07650	3.894e-218	689.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS3_k127_1287718_27	1347369.CCAD010000086_gene1750	8.093e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,1V3QD@1239|Firmicutes,4HHEF@91061|Bacilli,1ZBBX@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
MMS3_k127_1287718_11	861299.J421_2669	8.251e-121	394.0	COG0320@1|root,COG0320@2|Bacteria,1ZTA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
MMS3_k127_1287718_4	105559.Nwat_1144	6.005e-199	629.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
MMS3_k127_1287718_8	472759.Nhal_2901	7.262e-156	504.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	135613|Chromatiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_1287718_0	472759.Nhal_2900	0.0	1380.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
MMS3_k127_1287718_33	292459.STH1979	1.975e-10	68.0	COG1573@1|root,COG1573@2|Bacteria,1V2PR@1239|Firmicutes,24JK1@186801|Clostridia	186801|Clostridia	L	UreE urease accessory protein, C-terminal domain	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_1287718_10	398767.Glov_2052	1.354e-138	455.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42PVW@68525|delta/epsilon subdivisions,2WIMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
MMS3_k127_1287718_15	344747.PM8797T_15081	6.151e-86	295.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	MA20_02330	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_1287718_20	1120971.AUCA01000004_gene1336	2.596e-52	195.0	COG0584@1|root,COG0584@2|Bacteria,1TQ3Y@1239|Firmicutes,4HAI9@91061|Bacilli,279TU@186823|Alicyclobacillaceae	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
MMS3_k127_1287718_5	234267.Acid_2208	4.137e-195	620.0	COG1239@1|root,COG1239@2|Bacteria,3Y3FM@57723|Acidobacteria	57723|Acidobacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Sigma54_activat
MMS3_k127_1287718_9	1267533.KB906733_gene3299	3.967e-153	504.0	COG4867@1|root,COG4867@2|Bacteria,3Y2VU@57723|Acidobacteria,2JHSR@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
MMS3_k127_1287718_26	330214.NIDE0518	7.6e-34	151.0	COG2802@1|root,COG2802@2|Bacteria,3J13Q@40117|Nitrospirae	40117|Nitrospirae	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
MMS3_k127_1287718_14	1340493.JNIF01000003_gene2609	1.942e-93	319.0	COG0492@1|root,COG0492@2|Bacteria,3Y2NX@57723|Acidobacteria	57723|Acidobacteria	O	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
MMS3_k127_1287718_1	1382359.JIAL01000001_gene12	0.0	1132.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
MMS3_k127_1287718_25	13689.BV96_01910	5.402e-37	152.0	2EBPI@1|root,335PM@2|Bacteria,1NS9X@1224|Proteobacteria,2UR4S@28211|Alphaproteobacteria,2KDDF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1322903_1	479434.Sthe_0126	3.05e-132	430.0	COG2515@1|root,COG2515@2|Bacteria,2G6PX@200795|Chloroflexi,27YZ5@189775|Thermomicrobia	189775|Thermomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
MMS3_k127_1322903_22	502025.Hoch_5543	0.0007303	48.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,42ZS1@68525|delta/epsilon subdivisions,2WV25@28221|Deltaproteobacteria,2YV5R@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
MMS3_k127_1322903_17	886293.Sinac_3801	4.773e-18	98.0	COG1657@1|root,COG1657@2|Bacteria,2J0IG@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1322903_4	596152.DesU5LDRAFT_3456	1.351e-80	280.0	COG2006@1|root,COG2006@2|Bacteria,1R7BH@1224|Proteobacteria,42QGJ@68525|delta/epsilon subdivisions,2WJ1A@28221|Deltaproteobacteria,2MAYQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
MMS3_k127_1322903_15	1267533.KB906738_gene2047	6.675e-20	100.0	COG1430@1|root,COG1430@2|Bacteria,3Y5J5@57723|Acidobacteria,2JJXT@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
MMS3_k127_1322903_23	1287116.X734_15895	0.0009538	45.0	COG3847@1|root,COG3847@2|Bacteria,1NGVU@1224|Proteobacteria,2UJE8@28211|Alphaproteobacteria,43ME8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	PFAM Flp Fap pilin component	pilA	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
MMS3_k127_1322903_14	521674.Plim_0796	5.722e-20	96.0	COG4960@1|root,COG4960@2|Bacteria,2IZQF@203682|Planctomycetes	203682|Planctomycetes	OU	PFAM Peptidase A24A, prepilin type IV	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
MMS3_k127_1322903_20	572547.Amico_1204	4.381e-08	65.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
MMS3_k127_1322903_9	234267.Acid_1409	1.181e-45	176.0	COG3745@1|root,COG3745@2|Bacteria,3Y4HR@57723|Acidobacteria	57723|Acidobacteria	U	PFAM SAF domain	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
MMS3_k127_1322903_3	1340493.JNIF01000003_gene3295	1.5e-89	313.0	COG4964@1|root,COG4964@2|Bacteria,3Y3DF@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
MMS3_k127_1322903_11	1304872.JAGC01000003_gene2359	3.221e-37	162.0	COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
MMS3_k127_1322903_19	314232.SKA53_08486	7.357e-11	74.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,2P8H8@245186|Loktanella	28211|Alphaproteobacteria	U	AAA domain	minD	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
MMS3_k127_1322903_0	234267.Acid_1412	3.128e-161	519.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria	57723|Acidobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
MMS3_k127_1322903_6	1158292.JPOE01000005_gene1225	5.842e-57	216.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2VJ80@28216|Betaproteobacteria,1KNGV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Type II secretion system (T2SS), protein F	tadB1	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
MMS3_k127_1322903_7	1267533.KB906738_gene2056	6.233e-53	198.0	COG2064@1|root,COG2064@2|Bacteria,3Y4FI@57723|Acidobacteria,2JJ6X@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
MMS3_k127_1322903_21	402881.Plav_3497	4.152e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,1NMAU@1224|Proteobacteria,2UKZX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1
MMS3_k127_1322903_2	1128421.JAGA01000002_gene1253	2.588e-116	391.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
MMS3_k127_1322903_13	401053.AciPR4_0373	3.003e-22	113.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
MMS3_k127_1322903_12	1267534.KB906755_gene4635	3.208e-23	116.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
MMS3_k127_1322903_18	1380355.JNIJ01000015_gene5959	3.521e-17	95.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,3JT48@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS3_k127_1322903_5	448385.sce3280	1.15e-73	272.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2X7TS@28221|Deltaproteobacteria,2YXZZ@29|Myxococcales	28221|Deltaproteobacteria	K	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K12266	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
MMS3_k127_1322903_10	1382359.JIAL01000001_gene945	1.609e-43	166.0	COG1596@1|root,COG1596@2|Bacteria,3Y51C@57723|Acidobacteria,2JJMM@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
MMS3_k127_1322903_8	1125863.JAFN01000001_gene622	9.932e-47	178.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,42M2D@68525|delta/epsilon subdivisions,2WJU6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipopolysaccharide biosynthesis protein	wzc1	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
MMS3_k127_1328666_12	187303.BN69_0844	2.036e-27	128.0	COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,2UIK4@28211|Alphaproteobacteria,370CV@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
MMS3_k127_1328666_2	247490.KSU1_A0077	2.466e-194	615.0	COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes	203682|Planctomycetes	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
MMS3_k127_1328666_4	272134.KB731324_gene5863	2.317e-123	403.0	COG1941@1|root,COG1941@2|Bacteria	2|Bacteria	C	coenzyme F420 hydrogenase activity	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
MMS3_k127_1328666_7	448385.sce4573	4.354e-95	319.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WKKC@28221|Deltaproteobacteria,2Z328@29|Myxococcales	28221|Deltaproteobacteria	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	hdrF	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
MMS3_k127_1328666_10	272134.KB731324_gene5861	4.636e-48	179.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_1328666_3	272134.KB731324_gene5860	3.48e-150	491.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Aldo_ket_red,Fer4_22
MMS3_k127_1328666_9	1267533.KB906733_gene3083	1.649e-64	241.0	COG2208@1|root,COG2208@2|Bacteria,3Y6AE@57723|Acidobacteria,2JKYD@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
MMS3_k127_1328666_1	1379270.AUXF01000001_gene2513	1.344e-217	690.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	2|Bacteria	J	Amidase	gatA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS3_k127_1328666_11	1210884.HG799464_gene11143	4.501e-28	117.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMS3_k127_1328666_8	570268.ANBB01000039_gene3277	1.103e-82	287.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria,4EHI5@85012|Streptosporangiales	201174|Actinobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_1328666_0	1267533.KB906739_gene2748	1.193e-303	960.0	COG4774@1|root,COG4774@2|Bacteria,3Y6IC@57723|Acidobacteria,2JKCD@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_1328666_5	234267.Acid_7169	6.713e-122	414.0	28K04@1|root,2Z9Q3@2|Bacteria,3Y344@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1328666_6	1267534.KB906755_gene4091	5.347e-112	368.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1328666_13	234267.Acid_3898	2.232e-10	74.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
MMS3_k127_1337492_13	330214.NIDE1274	6.774e-06	55.0	COG4974@1|root,COG4974@2|Bacteria,3J1FQ@40117|Nitrospirae	40117|Nitrospirae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
MMS3_k127_1337492_5	941449.dsx2_0901	1.537e-62	237.0	COG0438@1|root,COG0438@2|Bacteria,1NPA5@1224|Proteobacteria,42Q3A@68525|delta/epsilon subdivisions,2WM0R@28221|Deltaproteobacteria,2M8E5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_1337492_9	1047013.AQSP01000133_gene2149	3.549e-42	161.0	COG1329@1|root,COG1329@2|Bacteria,2NPWZ@2323|unclassified Bacteria	2|Bacteria	K	CarD-like/TRCF domain	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
MMS3_k127_1337492_11	401053.AciPR4_0717	1.305e-34	144.0	COG0204@1|root,COG0204@2|Bacteria,3Y49D@57723|Acidobacteria,2JJ6K@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS3_k127_1337492_6	1449126.JQKL01000059_gene1853	2.741e-53	197.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,268RK@186813|unclassified Clostridiales	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
MMS3_k127_1337492_7	1090319.KE386571_gene329	1.592e-49	182.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2K4GG@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
MMS3_k127_1337492_4	644966.Tmar_1095	1.745e-64	234.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_1337492_3	192952.MM_1711	5.469e-73	258.0	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,2N9HJ@224756|Methanomicrobia	224756|Methanomicrobia	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
MMS3_k127_1337492_10	926566.Terro_1398	3.082e-39	163.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria,2JJ4I@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
MMS3_k127_1337492_2	1267533.KB906733_gene3221	1.213e-73	256.0	COG3279@1|root,COG3279@2|Bacteria,3Y3HR@57723|Acidobacteria,2JIXA@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
MMS3_k127_1337492_1	234267.Acid_2181	6.786e-97	334.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase internal region	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,His_kinase
MMS3_k127_1337492_8	671143.DAMO_1604	1.009e-48	180.0	COG1143@1|root,COG1143@2|Bacteria,2NPQR@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00337,ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
MMS3_k127_1337492_12	751944.HALDL1_06280	2.204e-24	111.0	COG2129@1|root,arCOG01145@2157|Archaea,2XV9E@28890|Euryarchaeota,23V3B@183963|Halobacteria	183963|Halobacteria	S	phosphoesterases, related to the Icc protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
MMS3_k127_1337492_0	1267535.KB906767_gene1558	3.056e-99	335.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria,2JIG8@204432|Acidobacteriia	204432|Acidobacteriia	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
MMS3_k127_1339946_3	290397.Adeh_2757	1.148e-16	88.0	COG3005@1|root,COG3005@2|Bacteria,1Q9NJ@1224|Proteobacteria,434HC@68525|delta/epsilon subdivisions,2WYUP@28221|Deltaproteobacteria,2Z0NR@29|Myxococcales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
MMS3_k127_1339946_1	340177.Cag_0498	4.309e-102	340.0	COG1117@1|root,COG1117@2|Bacteria,1FEHB@1090|Chlorobi	1090|Chlorobi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMS3_k127_1339946_2	671143.DAMO_1099	5.774e-68	239.0	COG0704@1|root,COG1392@1|root,COG0704@2|Bacteria,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU,PhoU_div
MMS3_k127_1339946_0	517417.Cpar_0368	6.058e-214	670.0	COG0372@1|root,COG0372@2|Bacteria,1FD5Z@1090|Chlorobi	1090|Chlorobi	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_1346004_3	1163407.UU7_05584	3.491e-17	87.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1X70E@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the HSP15 family	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
MMS3_k127_1346004_2	1382356.JQMP01000003_gene2419	2.211e-20	96.0	COG0789@1|root,COG0789@2|Bacteria,2G72X@200795|Chloroflexi,27YHN@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
MMS3_k127_1346004_1	525904.Tter_2296	1.108e-99	336.0	COG0484@1|root,COG0484@2|Bacteria,2NQI8@2323|unclassified Bacteria	2|Bacteria	O	DnaJ molecular chaperone homology domain	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
MMS3_k127_1346004_0	479434.Sthe_0441	0.0	1150.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS3_k127_1372375_6	1123248.KB893314_gene3458	9.848e-15	87.0	COG2318@1|root,COG2318@2|Bacteria,4NNRD@976|Bacteroidetes,1ITIY@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
MMS3_k127_1372375_4	1120970.AUBZ01000022_gene1310	6.714e-57	211.0	COG0391@1|root,COG0391@2|Bacteria,1NW3K@1224|Proteobacteria,1RQP9@1236|Gammaproteobacteria,468CT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0052	ybhK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
MMS3_k127_1372375_3	1380394.JADL01000004_gene6082	4.164e-60	216.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,2JQRY@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
MMS3_k127_1372375_2	1183438.GKIL_1866	1.391e-82	290.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	dtpT	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
MMS3_k127_1372375_7	401526.TcarDRAFT_1318	4.605e-07	59.0	2DNS7@1|root,32YWC@2|Bacteria,1UJJ5@1239|Firmicutes,4H5JW@909932|Negativicutes	909932|Negativicutes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMS3_k127_1372375_0	1128421.JAGA01000002_gene1399	4.85e-165	530.0	COG1032@1|root,COG1032@2|Bacteria,2NQJQ@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_1372375_1	338963.Pcar_1960	4.272e-135	444.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43SBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_1372375_5	395494.Galf_0430	3.06e-23	104.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,2VVHG@28216|Betaproteobacteria,44WG8@713636|Nitrosomonadales	28216|Betaproteobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMS3_k127_1372375_8	457398.HMPREF0326_02432	4.109e-06	53.0	2CG7V@1|root,32S3C@2|Bacteria,1QX2C@1224|Proteobacteria,43BVM@68525|delta/epsilon subdivisions,2X76A@28221|Deltaproteobacteria,2MH9T@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
MMS3_k127_1372375_9	660470.Theba_1569	3.674e-05	54.0	COG4502@1|root,COG4502@2|Bacteria,2GE34@200918|Thermotogae	200918|Thermotogae	S	PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
MMS3_k127_1412016_1	1123508.JH636440_gene2791	7.371e-05	54.0	COG2010@1|root,COG2010@2|Bacteria,2IZC1@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMS3_k127_1412016_0	234267.Acid_7252	1.384e-255	822.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1441356_1	1267533.KB906735_gene4448	3.817e-159	521.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
MMS3_k127_1441356_2	1038869.AXAN01000092_gene6966	3.96e-104	348.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,2VR9S@28216|Betaproteobacteria,1K2EA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
MMS3_k127_1441356_3	204669.Acid345_1010	6.995e-83	289.0	COG0429@1|root,COG0429@2|Bacteria,3Y3MP@57723|Acidobacteria,2JI5X@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
MMS3_k127_1441356_4	44251.PDUR_19700	6.642e-45	176.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,26TDD@186822|Paenibacillaceae	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMS3_k127_1441356_0	1185876.BN8_04568	6.902e-281	888.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47N4P@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
MMS3_k127_1441356_5	861299.J421_1390	8.67e-27	113.0	COG2318@1|root,COG2318@2|Bacteria,1ZV4X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1452054_4	452637.Oter_1814	5.534e-41	156.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1452054_1	1121422.AUMW01000026_gene381	2.745e-202	642.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8,1.2.1.99	ko:K00130,ko:K00135,ko:K09472,ko:K22187	ko00040,ko00250,ko00260,ko00310,ko00330,ko00350,ko00650,ko00760,ko01100,ko01120,map00040,map00250,map00260,map00310,map00330,map00350,map00650,map00760,map01100,map01120	M00027,M00136,M00555	R00713,R00714,R02401,R02565,R02566,R07417,R07418,R11768	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_1452054_0	335543.Sfum_3516	2.411e-279	867.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2MQTV@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
MMS3_k127_1452054_3	1297742.A176_03628	2.088e-70	247.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,42SKB@68525|delta/epsilon subdivisions,2WQ2K@28221|Deltaproteobacteria,2YV8W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
MMS3_k127_1452054_2	1499967.BAYZ01000195_gene3106	3.593e-152	497.0	COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	MA20_19960	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_1452054_6	388413.ALPR1_07240	1.106e-05	55.0	COG0454@1|root,COG0456@2|Bacteria,4PMKR@976|Bacteroidetes,47Y42@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_1458735_5	234267.Acid_0384	1.441e-142	477.0	COG0608@1|root,COG0608@2|Bacteria,3Y3HI@57723|Acidobacteria	57723|Acidobacteria	L	single-stranded-DNA-specific exonuclease RecJ	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
MMS3_k127_1458735_7	443144.GM21_1170	9.765e-105	349.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,43UDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
MMS3_k127_1458735_1	204669.Acid345_2747	0.0	1141.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria,2JIA9@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA-directed DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
MMS3_k127_1458735_3	335543.Sfum_2123	1.549e-206	654.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2MQ6H@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
MMS3_k127_1458735_22	100226.SCO4423	3.801e-17	94.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	afsK	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3,Pkinase
MMS3_k127_1458735_24	518766.Rmar_2120	3.444e-12	79.0	COG1308@1|root,COG1308@2|Bacteria,4NVAE@976|Bacteroidetes	976|Bacteroidetes	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
MMS3_k127_1458735_9	1151117.AJLF01000001_gene1372	2.745e-95	326.0	COG1167@1|root,arCOG00492@2157|Archaea,2XVD6@28890|Euryarchaeota,243KU@183968|Thermococci	183968|Thermococci	K	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
MMS3_k127_1458735_15	404589.Anae109_3408	3.083e-54	220.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
MMS3_k127_1458735_13	1265313.HRUBRA_01261	3.927e-59	215.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_1458735_12	1146883.BLASA_3993	2.583e-66	232.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria,4EWEE@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
MMS3_k127_1458735_16	665952.HMPREF1015_02407	8.77e-35	143.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,1ZGAT@1386|Bacillus	91061|Bacilli	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
MMS3_k127_1458735_20	290397.Adeh_3581	9.753e-27	119.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,2Z1V2@29|Myxococcales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
MMS3_k127_1458735_2	443143.GM18_1617	3.065e-251	803.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
MMS3_k127_1458735_8	1379698.RBG1_1C00001G0709	2.582e-97	330.0	COG1899@1|root,COG1899@2|Bacteria,2NR8I@2323|unclassified Bacteria	2|Bacteria	O	Deoxyhypusine synthase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
MMS3_k127_1458735_11	1379698.RBG1_1C00001G0708	1.196e-72	269.0	COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria	2|Bacteria	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_1458735_25	1089550.ATTH01000001_gene2437	1.601e-06	59.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
MMS3_k127_1458735_6	743299.Acife_1863	5.584e-115	380.0	arCOG03699@1|root,2Z8FU@2|Bacteria,1NMGQ@1224|Proteobacteria,1S4Z8@1236|Gammaproteobacteria,2NC8Q@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1458735_26	748280.NH8B_1148	1.587e-05	49.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1458735_14	240015.ACP_2871	1.811e-55	206.0	COG0503@1|root,COG0503@2|Bacteria,3Y30R@57723|Acidobacteria,2JHP2@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
MMS3_k127_1458735_21	204669.Acid345_3607	1.403e-21	97.0	COG1254@1|root,COG1254@2|Bacteria,3Y55N@57723|Acidobacteria,2JJSV@204432|Acidobacteriia	204432|Acidobacteriia	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
MMS3_k127_1458735_0	234267.Acid_3530	0.0	1164.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1458735_23	246194.CHY_0865	4.906e-13	74.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,24V8A@186801|Clostridia,42HG9@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_1458735_18	420662.Mpe_A1019	6.95e-29	131.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,2VQIK@28216|Betaproteobacteria,1KKST@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
MMS3_k127_1458735_19	331869.BAL199_03289	7.606e-27	115.0	COG3741@1|root,COG3741@2|Bacteria,1NBYI@1224|Proteobacteria	1224|Proteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1458735_17	861299.J421_1228	4.281e-31	126.0	2E9H4@1|root,333Q5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1458735_4	99598.Cal7507_4212	2.938e-168	539.0	COG0683@1|root,COG0683@2|Bacteria,1G29H@1117|Cyanobacteria,1HMXT@1161|Nostocales	1117|Cyanobacteria	E	TIGRFAM urea ABC transporter, urea binding protein	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
MMS3_k127_1458735_10	269797.Mbar_A1243	7.568e-79	290.0	arCOG02362@1|root,arCOG02362@2157|Archaea	2157|Archaea	-	-	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,dCache_1
MMS3_k127_1461674_10	204669.Acid345_0760	1.39e-05	52.0	COG2010@1|root,COG2010@2|Bacteria,3Y5MU@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMS3_k127_1461674_9	204669.Acid345_3827	2.183e-10	74.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria,2JI2I@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1461674_4	401053.AciPR4_1212	1.696e-58	218.0	COG3303@1|root,COG3303@2|Bacteria,3Y999@57723|Acidobacteria,2JP5G@204432|Acidobacteriia	204432|Acidobacteriia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMS3_k127_1461674_7	697281.Mahau_1365	2.072e-16	83.0	COG0125@1|root,COG0125@2|Bacteria,1V07S@1239|Firmicutes,24F7F@186801|Clostridia,42I4T@68295|Thermoanaerobacterales	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
MMS3_k127_1461674_2	517418.Ctha_1162	2.829e-105	379.0	COG0248@1|root,COG0248@2|Bacteria,1FDDR@1090|Chlorobi	1090|Chlorobi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
MMS3_k127_1461674_8	211114.JOEF01000002_gene4518	7.007e-12	79.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4E2RA@85010|Pseudonocardiales	201174|Actinobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
MMS3_k127_1461674_6	383372.Rcas_1740	4.121e-26	113.0	COG2062@1|root,COG2062@2|Bacteria,2GB93@200795|Chloroflexi,377KE@32061|Chloroflexia	32061|Chloroflexia	T	TIGRFAM phosphohistidine phosphatase SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
MMS3_k127_1461674_3	472759.Nhal_3593	2.167e-61	223.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,1RRKY@1236|Gammaproteobacteria,1X0TK@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
MMS3_k127_1461674_5	1267533.KB906736_gene851	2.897e-47	179.0	COG0682@1|root,COG0682@2|Bacteria,3Y4QQ@57723|Acidobacteria,2JJ7E@204432|Acidobacteriia	204432|Acidobacteriia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
MMS3_k127_1461674_1	240015.ACP_2554	7.407e-113	377.0	COG0581@1|root,COG0581@2|Bacteria,3Y3JF@57723|Acidobacteria,2JHVP@204432|Acidobacteriia	204432|Acidobacteriia	P	Phosphate transport system permease protein PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS3_k127_1461674_0	240015.ACP_2553	1.821e-133	433.0	COG0573@1|root,COG0573@2|Bacteria,3Y42Y@57723|Acidobacteria,2JIJN@204432|Acidobacteriia	204432|Acidobacteriia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS3_k127_1469838_12	886379.AEWI01000053_gene2705	5.648e-20	90.0	2B9ZZ@1|root,323DM@2|Bacteria,4NTEB@976|Bacteroidetes,2FU8G@200643|Bacteroidia,3XKW7@558415|Marinilabiliaceae	976|Bacteroidetes	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1469838_14	1150469.RSPPHO_03245	2.748e-19	89.0	2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria	1224|Proteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1469838_9	1121434.AULY01000004_gene268	3.358e-45	164.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,42S33@68525|delta/epsilon subdivisions,2WNKG@28221|Deltaproteobacteria,2MC3F@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1469838_18	1280682.AUKA01000016_gene2129	3.034e-05	49.0	29TS8@1|root,30F0H@2|Bacteria,1UD83@1239|Firmicutes,25HVT@186801|Clostridia,4C0IE@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1469838_17	536227.CcarbDRAFT_5305	1.815e-05	49.0	2BF0I@1|root,328S9@2|Bacteria,1UUQR@1239|Firmicutes,257HC@186801|Clostridia,36TBS@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1469838_6	1267534.KB906756_gene630	7.909e-94	316.0	2CK1E@1|root,33T2R@2|Bacteria,3Y7DJ@57723|Acidobacteria,2JM38@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1469838_11	1499686.BN1079_03470	1.277e-31	136.0	28IX1@1|root,2Z8V3@2|Bacteria,1N0WD@1224|Proteobacteria,1RSH6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
MMS3_k127_1469838_16	105422.BBPM01000003_gene5686	3.022e-13	80.0	COG0500@1|root,COG1695@1|root,COG1695@2|Bacteria,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,2NFD4@228398|Streptacidiphilus	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,PadR
MMS3_k127_1469838_13	861299.J421_0325	1.874e-19	103.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_1469838_5	1382359.JIAL01000001_gene2823	6.168e-98	325.0	COG0217@1|root,COG0217@2|Bacteria,3Y2UW@57723|Acidobacteria,2JIJW@204432|Acidobacteriia	204432|Acidobacteriia	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMS3_k127_1469838_10	1128398.Curi_c10550	2.727e-41	162.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,268AF@186813|unclassified Clostridiales	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
MMS3_k127_1469838_8	1267535.KB906767_gene34	1.591e-53	194.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria,2JJCJ@204432|Acidobacteriia	204432|Acidobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
MMS3_k127_1469838_1	398767.Glov_2173	8.368e-140	451.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
MMS3_k127_1469838_2	1382359.JIAL01000001_gene2796	9.029e-135	439.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria,2JIAW@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
MMS3_k127_1469838_3	498761.HM1_1835	6.131e-108	361.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
MMS3_k127_1469838_7	1198114.AciX9_2897	1.453e-61	236.0	COG1404@1|root,COG5164@1|root,COG1404@2|Bacteria,COG5164@2|Bacteria,3Y5WB@57723|Acidobacteria,2JK6I@204432|Acidobacteriia	204432|Acidobacteriia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
MMS3_k127_1469838_15	1229172.JQFA01000004_gene702	2.061e-15	85.0	COG1670@1|root,COG1670@2|Bacteria,1GA76@1117|Cyanobacteria,1HGA7@1150|Oscillatoriales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
MMS3_k127_1469838_0	706587.Desti_5047	5.631e-157	524.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
MMS3_k127_1469838_4	330214.NIDE4314	9.162e-105	349.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1475270_1	1267535.KB906767_gene4620	5.088e-76	266.0	COG2234@1|root,COG2234@2|Bacteria,3Y406@57723|Acidobacteria,2JIRZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_1475270_4	379066.GAU_3293	7.991e-31	126.0	294EW@1|root,2ZRUR@2|Bacteria,1ZV2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
MMS3_k127_1475270_0	1379698.RBG1_1C00001G0513	3.453e-138	452.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
MMS3_k127_1475270_2	1173025.GEI7407_0248	8.382e-65	229.0	COG0705@1|root,COG0705@2|Bacteria,1FZY1@1117|Cyanobacteria,1H9IP@1150|Oscillatoriales	1117|Cyanobacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMS3_k127_1475270_3	743721.Psesu_1735	9.008e-56	210.0	COG0079@1|root,COG0079@2|Bacteria,1R774@1224|Proteobacteria,1SYBU@1236|Gammaproteobacteria,1X4G3@135614|Xanthomonadales	135614|Xanthomonadales	E	aminotransferase	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_1502996_6	1267535.KB906767_gene1065	9.625e-63	217.0	COG1970@1|root,COG1970@2|Bacteria,3Y58F@57723|Acidobacteria,2JJRP@204432|Acidobacteriia	204432|Acidobacteriia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
MMS3_k127_1502996_10	377629.TERTU_3239	1.017e-07	63.0	28XDT@1|root,2ZJBI@2|Bacteria,1PCGE@1224|Proteobacteria,1SXH3@1236|Gammaproteobacteria,2PPFX@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1502996_0	745411.B3C1_04575	8.003e-149	487.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1J58C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2939 Carboxypeptidase C (cathepsin A)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
MMS3_k127_1502996_9	926569.ANT_23110	6.376e-26	117.0	COG1434@1|root,COG1434@2|Bacteria,2G9DV@200795|Chloroflexi	200795|Chloroflexi	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
MMS3_k127_1502996_8	698769.JFBD01000010_gene2388	1.393e-32	139.0	COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,4C5UQ@84406|Virgibacillus	91061|Bacilli	U	ABC 3 transport family	-	-	-	ko:K19976	ko02010,map02010	M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.15	-	-	ABC-3
MMS3_k127_1502996_7	661367.LLO_2971	9.749e-57	206.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,1JFVA@118969|Legionellales	118969|Legionellales	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
MMS3_k127_1502996_1	309801.trd_0582	5.169e-147	475.0	COG1064@1|root,COG1064@2|Bacteria,2G829@200795|Chloroflexi,27YST@189775|Thermomicrobia	189775|Thermomicrobia	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
MMS3_k127_1502996_2	680198.SCAB_84421	1.4e-108	363.0	COG2042@1|root,COG3376@2|Bacteria,2GJZB@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the NiCoT transporter (TC 2.A.52) family	nicT	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
MMS3_k127_1502996_3	1121943.KB899997_gene1720	3.878e-106	353.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SZ0M@1236|Gammaproteobacteria,1XKZK@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_1502996_4	1173022.Cri9333_1601	6.868e-97	329.0	COG2084@1|root,COG2084@2|Bacteria,1G34X@1117|Cyanobacteria,1HBU0@1150|Oscillatoriales	1117|Cyanobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_1502996_5	1121405.dsmv_1452	8.034e-83	282.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2MI37@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
MMS3_k127_1519627_6	234267.Acid_3800	5.958e-49	181.0	COG4097@1|root,COG4097@2|Bacteria	2|Bacteria	P	nitric oxide dioxygenase activity	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
MMS3_k127_1519627_0	240015.ACP_2408	1.007e-220	720.0	COG1629@1|root,COG4771@2|Bacteria,3Y4C9@57723|Acidobacteria,2JMK8@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_1519627_11	1144275.COCOR_03667	2.774e-05	56.0	COG4219@1|root,COG4219@2|Bacteria,1PJ0I@1224|Proteobacteria	1224|Proteobacteria	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313,Peptidase_M23,Peptidase_M56,TonB_C
MMS3_k127_1519627_9	234267.Acid_1488	1.198e-25	111.0	COG3682@1|root,COG3682@2|Bacteria,3Y8QA@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
MMS3_k127_1519627_5	290398.Csal_0468	1.292e-76	267.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,1XH5V@135619|Oceanospirillales	135619|Oceanospirillales	S	nucleoside-diphosphate sugar epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
MMS3_k127_1519627_10	1304888.ATWF01000002_gene341	4.599e-19	102.0	COG1309@1|root,COG1309@2|Bacteria,2GGM9@200930|Deferribacteres	200930|Deferribacteres	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1519627_8	518766.Rmar_1777	6.353e-44	179.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes	976|Bacteroidetes	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMS3_k127_1519627_2	518766.Rmar_1778	1.802e-90	308.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1FIPW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1519627_7	518766.Rmar_1779	7.013e-46	189.0	COG1538@1|root,COG1538@2|Bacteria,4NDZ6@976|Bacteroidetes	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_1519627_1	234267.Acid_5990	7.163e-102	340.0	COG1131@1|root,COG1131@2|Bacteria,3Y3VU@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1519627_4	518766.Rmar_1781	1.262e-88	306.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes	976|Bacteroidetes	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_1519627_3	518766.Rmar_1782	8.074e-89	321.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes	976|Bacteroidetes	V	transport, permease protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_1523616_7	671143.DAMO_2457	1.615e-92	308.0	COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria	2|Bacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMS3_k127_1523616_13	234267.Acid_1287	8.109e-33	139.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMS3_k127_1523616_16	1235279.C772_00245	1.85e-07	62.0	COG3861@1|root,COG3861@2|Bacteria,1V5RZ@1239|Firmicutes,4HHAU@91061|Bacilli,26FBA@186818|Planococcaceae	91061|Bacilli	S	Heat induced stress protein YflT	-	-	-	-	-	-	-	-	-	-	-	-	YflT
MMS3_k127_1523616_11	234267.Acid_4250	1.04e-44	178.0	COG0644@1|root,COG0644@2|Bacteria,3Y5JJ@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Pyr_redox_2
MMS3_k127_1523616_4	234267.Acid_1490	2.354e-148	507.0	COG3276@1|root,COG3276@2|Bacteria,3Y6R2@57723|Acidobacteria	57723|Acidobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
MMS3_k127_1523616_2	634956.Geoth_0450	2.355e-202	654.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1WF8G@129337|Geobacillus	91061|Bacilli	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
MMS3_k127_1523616_8	234267.Acid_0778	2.546e-86	302.0	COG2379@1|root,COG2379@2|Bacteria,3Y2XC@57723|Acidobacteria	57723|Acidobacteria	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
MMS3_k127_1523616_14	671143.DAMO_2528	2.005e-26	120.0	COG2177@1|root,COG2177@2|Bacteria,2NPIM@2323|unclassified Bacteria	2|Bacteria	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
MMS3_k127_1523616_9	1121920.AUAU01000005_gene1090	4.155e-75	259.0	COG2884@1|root,COG2884@2|Bacteria	2|Bacteria	D	Cell division ATP-binding protein ftsE	ftsE	GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
MMS3_k127_1523616_3	243231.GSU3380	1.362e-158	515.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
MMS3_k127_1523616_1	572477.Alvin_1133	1.568e-229	721.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1WWJT@135613|Chromatiales	135613|Chromatiales	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
MMS3_k127_1523616_15	338963.Pcar_3124	1.312e-17	93.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2WNWA@28221|Deltaproteobacteria,43SHN@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1523616_17	1198114.AciX9_2498	5.585e-06	55.0	COG3678@1|root,COG3678@2|Bacteria,3Y8CZ@57723|Acidobacteria,2JNCU@204432|Acidobacteriia	204432|Acidobacteriia	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1523616_10	1047013.AQSP01000118_gene1234	1.986e-69	259.0	COG1538@1|root,COG1538@2|Bacteria,2NP5D@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
MMS3_k127_1523616_6	671143.DAMO_3154	4.413e-94	315.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1523616_5	269799.Gmet_1651	2.685e-113	379.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,43US6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMS3_k127_1523616_0	1173023.KE650771_gene3661	0.0	1240.0	COG0841@1|root,COG0841@2|Bacteria,1G0C2@1117|Cyanobacteria,1JIE7@1189|Stigonemataceae	1117|Cyanobacteria	V	MMPL family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
MMS3_k127_1523616_12	309801.trd_1324	3.343e-37	146.0	COG0801@1|root,COG0801@2|Bacteria,2G6YT@200795|Chloroflexi,27YCY@189775|Thermomicrobia	189775|Thermomicrobia	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
MMS3_k127_1627121_6	401526.TcarDRAFT_0760	2.404e-24	115.0	COG4636@1|root,COG4636@2|Bacteria,1V46Z@1239|Firmicutes	1239|Firmicutes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox,Uma2
MMS3_k127_1627121_4	1121091.AUMP01000033_gene1598	5.596e-39	153.0	COG1670@1|root,COG1670@2|Bacteria,1V4IY@1239|Firmicutes,4HG60@91061|Bacilli	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	ykkB	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_1627121_0	1121015.N789_10470	1.317e-128	417.0	COG1881@1|root,COG1881@2|Bacteria,1PHET@1224|Proteobacteria,1RWC4@1236|Gammaproteobacteria,1XA7U@135614|Xanthomonadales	135614|Xanthomonadales	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
MMS3_k127_1627121_3	477184.KYC_07785	6.406e-59	209.0	COG1764@1|root,COG1764@2|Bacteria,1RHVR@1224|Proteobacteria,2VQHP@28216|Betaproteobacteria,3T44A@506|Alcaligenaceae	28216|Betaproteobacteria	O	redox protein regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS3_k127_1627121_9	1121377.KB906398_gene2488	2.665e-09	61.0	2AAWD@1|root,3109H@2|Bacteria	2|Bacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
MMS3_k127_1627121_7	33178.CADATEAP00004055	1.185e-21	100.0	2AAWD@1|root,2SAUR@2759|Eukaryota,39YPR@33154|Opisthokonta,3NYJM@4751|Fungi,3R1JE@4890|Ascomycota,20P6X@147545|Eurotiomycetes	4751|Fungi	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
MMS3_k127_1627121_1	1122604.JONR01000003_gene1527	7.716e-99	337.0	COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,1RWGW@1236|Gammaproteobacteria,1X55V@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMS3_k127_1627121_2	861299.J421_4125	5.664e-94	310.0	COG0154@1|root,COG0154@2|Bacteria,1ZT2R@142182|Gemmatimonadetes	2|Bacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_1638597_2	1121380.JNIW01000054_gene3197	9.627e-151	494.0	COG0277@1|root,COG0277@2|Bacteria,1WI90@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_1638597_3	639030.JHVA01000001_gene1843	1.287e-120	406.0	COG0165@1|root,COG0165@2|Bacteria,3Y7F3@57723|Acidobacteria,2JM7C@204432|Acidobacteriia	204432|Acidobacteriia	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
MMS3_k127_1638597_0	861299.J421_1758	5.301e-188	605.0	COG0591@1|root,COG0591@2|Bacteria,1ZT93@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
MMS3_k127_1638597_5	926550.CLDAP_01360	3.245e-65	227.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
MMS3_k127_1638597_1	234267.Acid_5043	4.886e-152	501.0	COG0026@1|root,COG0026@2|Bacteria,3Y3RI@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
MMS3_k127_1638597_4	1415756.JQMY01000001_gene1945	4.672e-91	314.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
MMS3_k127_1638597_6	686340.Metal_0426	1.318e-42	161.0	COG1917@1|root,COG1917@2|Bacteria,1QEE2@1224|Proteobacteria,1SEI9@1236|Gammaproteobacteria,1XF2Z@135618|Methylococcales	135618|Methylococcales	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1642378_8	1047013.AQSP01000134_gene1332	1.166e-81	293.0	COG1538@1|root,COG1538@2|Bacteria,2NP5D@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
MMS3_k127_1642378_11	1089553.Tph_c14410	3.193e-59	211.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,42FJS@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
MMS3_k127_1642378_10	867903.ThesuDRAFT_00591	1.652e-62	226.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3WCIF@538999|Clostridiales incertae sedis	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
MMS3_k127_1642378_5	234267.Acid_3241	2.098e-92	310.0	COG0020@1|root,COG0020@2|Bacteria,3Y485@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
MMS3_k127_1642378_14	498761.HM1_2262	1.106e-35	148.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,25HJP@186801|Clostridia	186801|Clostridia	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
MMS3_k127_1642378_3	1232410.KI421418_gene2268	5.71e-122	405.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria,43SBW@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
MMS3_k127_1642378_6	1499967.BAYZ01000078_gene992	1.521e-89	310.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
MMS3_k127_1642378_18	234267.Acid_2436	8.711e-10	70.0	COG3170@1|root,COG3170@2|Bacteria,3Y4RX@57723|Acidobacteria	57723|Acidobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1642378_0	479434.Sthe_1801	5.347e-162	520.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_1642378_2	264732.Moth_1246	1.949e-134	436.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42EWI@68295|Thermoanaerobacterales	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
MMS3_k127_1642378_1	370438.PTH_0973	1.493e-142	468.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,2602S@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
MMS3_k127_1642378_9	335543.Sfum_3202	3.147e-66	239.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2MQX5@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
MMS3_k127_1642378_4	316067.Geob_1300	7.756e-106	359.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
MMS3_k127_1642378_15	589865.DaAHT2_2551	1.185e-33	140.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,2MHT7@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
MMS3_k127_1642378_13	240015.ACP_1008	2.801e-38	164.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria,2JI1N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
MMS3_k127_1642378_19	1382359.JIAL01000001_gene2418	3.152e-09	68.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
MMS3_k127_1642378_17	338966.Ppro_1509	4.551e-13	72.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42WTD@68525|delta/epsilon subdivisions,2WSRU@28221|Deltaproteobacteria,43VEC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
MMS3_k127_1642378_12	1047013.AQSP01000119_gene1285	3.817e-57	208.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
MMS3_k127_1642378_16	1121396.KB893123_gene1067	1.237e-15	81.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2WRI4@28221|Deltaproteobacteria,2MKRV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
MMS3_k127_1642378_7	1047013.AQSP01000123_gene1523	1.029e-85	317.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_1658295_31	518766.Rmar_0555	2.151e-41	158.0	COG3265@1|root,COG3265@2|Bacteria,4NQI4@976|Bacteroidetes	976|Bacteroidetes	G	TIGRFAM carbohydrate kinase, thermoresistant glucokinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	SKI
MMS3_k127_1658295_38	479434.Sthe_2089	1.871e-13	80.0	COG4096@1|root,COG4096@2|Bacteria,2G6UT@200795|Chloroflexi	200795|Chloroflexi	L	Type III restriction protein res subunit	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	CarboxypepD_reg,EcoEI_R_C,HSDR_N,Helicase_C,ResIII
MMS3_k127_1658295_13	414684.RC1_1859	1.767e-135	442.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,2JPHC@204441|Rhodospirillales	204441|Rhodospirillales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1658295_36	1234364.AMSF01000015_gene3341	1.742e-29	124.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1S617@1236|Gammaproteobacteria,1X75U@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
MMS3_k127_1658295_12	306281.AJLK01000103_gene3364	9.775e-167	529.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria,1JJ7I@1189|Stigonemataceae	2|Bacteria	C	Aldo/keto reductase family	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
MMS3_k127_1658295_16	525904.Tter_0098	7.578e-114	382.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
MMS3_k127_1658295_32	671143.DAMO_3126	5.581e-38	155.0	COG2267@1|root,COG2267@2|Bacteria,2NQ6U@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	3.7.1.17	ko:K16050	ko00984,ko01100,ko01120,ko01220,map00984,map01100,map01120,map01220	-	R09883	RC02018,RC02740	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMS3_k127_1658295_1	234267.Acid_3530	0.0	1226.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1658295_9	479434.Sthe_2106	9.848e-179	571.0	COG0438@1|root,COG0438@2|Bacteria,2G8D2@200795|Chloroflexi,27YUH@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
MMS3_k127_1658295_6	983917.RGE_40040	5.702e-204	654.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,2VYC3@28216|Betaproteobacteria,1KP31@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	oligoendopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
MMS3_k127_1658295_3	504472.Slin_3267	5.9e-250	792.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
MMS3_k127_1658295_5	204669.Acid345_3443	6.147e-214	681.0	COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria,2JIRH@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_1658295_8	765420.OSCT_1463	7.547e-179	572.0	COG0626@1|root,COG0626@2|Bacteria,2G7Q6@200795|Chloroflexi,3770M@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_1658295_7	1121033.AUCF01000021_gene2889	3.596e-193	612.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria,2JQ2N@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_1658295_30	316067.Geob_2630	1.669e-42	169.0	COG0457@1|root,COG0457@2|Bacteria,1QXNU@1224|Proteobacteria,43C4R@68525|delta/epsilon subdivisions,2X7F5@28221|Deltaproteobacteria,43SFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_2,TPR_8
MMS3_k127_1658295_34	1303518.CCALI_00604	1.874e-34	136.0	COG2151@1|root,COG2151@2|Bacteria	2|Bacteria	L	metal-sulfur cluster biosynthetic enzyme	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
MMS3_k127_1658295_29	1038869.AXAN01000012_gene6394	5.219e-54	208.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ3A@28216|Betaproteobacteria,1K7JP@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMS3_k127_1658295_10	671143.DAMO_2380	6.317e-178	588.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
MMS3_k127_1658295_18	215803.DB30_6994	3.119e-106	362.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2WN3M@28221|Deltaproteobacteria,2YY27@29|Myxococcales	28221|Deltaproteobacteria	O	Uncharacterized protein family (UPF0051)	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
MMS3_k127_1658295_17	472759.Nhal_0689	1.205e-108	375.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1WWC1@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMS3_k127_1658295_2	1382359.JIAL01000001_gene678	8.538e-265	820.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
MMS3_k127_1658295_35	404589.Anae109_0639	4.016e-30	123.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria	1224|Proteobacteria	S	Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0034986,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	iAPECO1_1312.APECO1_3997,iB21_1397.B21_02384,iBWG_1329.BWG_2292,iE2348C_1286.E2348C_2811,iEC042_1314.EC042_2732,iEC55989_1330.EC55989_2813,iECABU_c1320.ECABU_c28340,iECBD_1354.ECBD_1156,iECB_1328.ECB_02420,iECDH10B_1368.ECDH10B_2695,iECD_1391.ECD_02420,iECED1_1282.ECED1_2959,iECIAI1_1343.ECIAI1_2580,iECIAI39_1322.ECIAI39_2729,iECNA114_1301.ECNA114_2607,iECO103_1326.ECO103_3045,iECO111_1330.ECO111_3252,iECO26_1355.ECO26_3575,iECOK1_1307.ECOK1_2877,iECP_1309.ECP_2533,iECS88_1305.ECS88_2704,iECSE_1348.ECSE_2814,iECSF_1327.ECSF_2372,iECSP_1301.ECSP_3472,iECUMN_1333.ECUMN_2848,iECW_1372.ECW_m2754,iECs_1301.ECs3394,iEKO11_1354.EKO11_1205,iETEC_1333.ETEC_2685,iEcDH1_1363.EcDH1_1140,iEcSMS35_1347.EcSMS35_2681,iEcolC_1368.EcolC_1149,iG2583_1286.G2583_3058,iJO1366.b2528,iLF82_1304.LF82_1120,iNRG857_1313.NRG857_12580,iSBO_1134.SBO_2552,iSDY_1059.SDY_2724,iSF_1195.SF2575,iSSON_1240.SSON_2610,iS_1188.S2747,iUMN146_1321.UM146_04060,iUMNK88_1353.UMNK88_3181,iWFL_1372.ECW_m2754,iY75_1357.Y75_RS13195,iZ_1308.Z3795,ic_1306.c3053	Fe-S_biosyn
MMS3_k127_1658295_25	1267535.KB906767_gene19	9.845e-65	236.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene19|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1658295_11	1267535.KB906767_gene18	1.796e-174	564.0	COG0038@1|root,COG0038@2|Bacteria,3Y2G4@57723|Acidobacteria,2JIJC@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
MMS3_k127_1658295_14	292459.STH1624	5.624e-123	410.0	COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,25EPJ@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1658295_28	1274374.CBLK010000048_gene1941	2.077e-54	200.0	COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,26RWT@186822|Paenibacillaceae	91061|Bacilli	S	deacetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
MMS3_k127_1658295_0	247490.KSU1_C0704	0.0	1246.0	COG0841@1|root,COG0841@2|Bacteria,2IY6W@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07788	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
MMS3_k127_1658295_15	448385.sce5059	2.901e-115	391.0	COG1409@1|root,COG1409@2|Bacteria,1R70J@1224|Proteobacteria,437FQ@68525|delta/epsilon subdivisions,2X2NB@28221|Deltaproteobacteria,2YTZ0@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
MMS3_k127_1658295_23	378806.STAUR_4012	1.557e-67	243.0	COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,42SJT@68525|delta/epsilon subdivisions,2WP3F@28221|Deltaproteobacteria,2YURW@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
MMS3_k127_1658295_4	243231.GSU2350	1.449e-236	748.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
MMS3_k127_1658295_24	1183438.GKIL_0197	4.969e-66	235.0	COG3264@1|root,COG3264@2|Bacteria,1G2P9@1117|Cyanobacteria	1117|Cyanobacteria	MT	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
MMS3_k127_1658295_21	404589.Anae109_1694	1.133e-91	312.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
MMS3_k127_1658295_26	1121033.AUCF01000006_gene4211	3.729e-62	235.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria,2JR2J@204441|Rhodospirillales	204441|Rhodospirillales	G	transport system permease	-	-	-	ko:K02026,ko:K05815,ko:K10238	ko02010,map02010	M00198,M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17,3.A.1.1.3	-	-	BPD_transp_1
MMS3_k127_1658295_27	1541065.JRFE01000017_gene225	1.481e-61	236.0	COG1175@1|root,COG1175@2|Bacteria,1G0YN@1117|Cyanobacteria,3VI3Y@52604|Pleurocapsales	1117|Cyanobacteria	G	PFAM Binding-protein-dependent transport system inner membrane component	ugpA	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
MMS3_k127_1658295_20	1173024.KI912151_gene1870	3.234e-102	349.0	COG1653@1|root,COG1653@2|Bacteria,1G0AA@1117|Cyanobacteria,1JJ8D@1189|Stigonemataceae	1117|Cyanobacteria	G	Bacterial extracellular solute-binding protein	ugpB	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
MMS3_k127_1658295_22	104623.Ser39006_02654	4.193e-84	291.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
MMS3_k127_1658295_37	314345.SPV1_04338	5.263e-20	95.0	2DM91@1|root,327BS@2|Bacteria,1R3C3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1658295_19	471854.Dfer_1708	4.3e-104	364.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
MMS3_k127_1658295_33	886293.Sinac_0142	5.251e-37	148.0	COG0526@1|root,COG0526@2|Bacteria,2IZW1@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
MMS3_k127_165925_28	1047013.AQSP01000085_gene1984	4.2e-19	96.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin_GH,Pilin_PilA
MMS3_k127_165925_12	1379270.AUXF01000003_gene3856	8.111e-79	275.0	COG1680@1|root,COG1680@2|Bacteria,1ZT58@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_165925_11	525904.Tter_1512	1.711e-80	279.0	COG2103@1|root,COG2103@2|Bacteria,2NP6Y@2323|unclassified Bacteria	2|Bacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
MMS3_k127_165925_9	292459.STH1821	2.929e-86	297.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_165925_1	304371.MCP_1463	2.43e-177	564.0	COG0192@1|root,arCOG07444@2157|Archaea	2157|Archaea	H	S-adenosylmethionine synthetase, C-terminal domain	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
MMS3_k127_165925_23	469383.Cwoe_1915	2.702e-33	147.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
MMS3_k127_165925_3	1047013.AQSP01000132_gene1731	7.314e-127	436.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	-	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
MMS3_k127_165925_14	1267534.KB906759_gene1669	1.652e-72	258.0	COG1612@1|root,COG1612@2|Bacteria,3Y3C7@57723|Acidobacteria,2JHS4@204432|Acidobacteriia	204432|Acidobacteriia	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
MMS3_k127_165925_17	1047013.AQSP01000134_gene1379	2.281e-57	209.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
MMS3_k127_165925_8	1047013.AQSP01000134_gene1378	4.524e-89	300.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMS3_k127_165925_16	1499967.BAYZ01000157_gene585	9.703e-58	204.0	COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria	2|Bacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
MMS3_k127_165925_6	760568.Desku_1329	4.292e-106	362.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,2609C@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
MMS3_k127_165925_4	269799.Gmet_0942	4.423e-115	391.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,43TM9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
MMS3_k127_165925_18	1121920.AUAU01000023_gene2424	6.169e-56	204.0	COG0811@1|root,COG0811@2|Bacteria,3Y2T8@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
MMS3_k127_165925_27	1304885.AUEY01000054_gene165	8.431e-21	97.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2MKKC@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
MMS3_k127_165925_30	1198114.AciX9_3606	5.12e-05	54.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria,2JHKT@204432|Acidobacteriia	204432|Acidobacteriia	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
MMS3_k127_165925_15	1047013.AQSP01000135_gene1613	3.462e-69	260.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
MMS3_k127_165925_22	319225.Plut_0616	4.9e-34	142.0	COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi	1090|Chlorobi	M	PFAM OmpA MotB domain protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
MMS3_k127_165925_29	1379698.RBG1_1C00001G0502	6.155e-19	100.0	COG1729@1|root,COG1729@2|Bacteria,2NQ0B@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
MMS3_k127_165925_19	215803.DB30_3249	8.111e-45	166.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
MMS3_k127_165925_0	518766.Rmar_2546	8.085e-222	705.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1FJ35@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_165925_20	483219.LILAB_25490	5.382e-43	164.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_165925_5	1415779.JOMH01000001_gene2944	8.254e-115	391.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1X33X@135614|Xanthomonadales	135614|Xanthomonadales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
MMS3_k127_165925_26	631362.Thi970DRAFT_02459	6.001e-21	100.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1WYUA@135613|Chromatiales	135613|Chromatiales	G	Phosphotransferase System	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
MMS3_k127_165925_21	1123503.KB908056_gene2177	3.706e-35	142.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,2KGF3@204458|Caulobacterales	204458|Caulobacterales	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
MMS3_k127_165925_13	682795.AciX8_1907	1.29e-78	275.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria,2JHJM@204432|Acidobacteriia	204432|Acidobacteriia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
MMS3_k127_165925_10	1242864.D187_001236	2.604e-81	282.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,2YUU0@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
MMS3_k127_165925_25	1121423.JONT01000003_gene983	2.132e-24	111.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,261QJ@186807|Peptococcaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
MMS3_k127_165925_2	1232410.KI421421_gene3588	1.411e-132	437.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
MMS3_k127_165925_7	1340493.JNIF01000003_gene2837	1.172e-98	327.0	COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
MMS3_k127_165925_24	204669.Acid345_1660	1.486e-24	119.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
MMS3_k127_1660968_18	1122605.KB893637_gene3141	3.665e-13	72.0	2E32R@1|root,32Y2Y@2|Bacteria,4NVIY@976|Bacteroidetes,1IU4T@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1660968_14	926560.KE387027_gene964	9.291e-25	112.0	COG5516@1|root,COG5516@2|Bacteria,1WMR5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
MMS3_k127_1660968_10	1410653.JHVC01000001_gene1911	1.33e-65	245.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,36UWY@31979|Clostridiaceae	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_1660968_20	479434.Sthe_1966	2.462e-12	69.0	COG3634@1|root,COG3634@2|Bacteria,2GBT2@200795|Chloroflexi,27Z89@189775|Thermomicrobia	189775|Thermomicrobia	O	alkyl hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1660968_13	1499967.BAYZ01000177_gene5710	2.664e-30	124.0	COG3634@1|root,COG3634@2|Bacteria,2NPR2@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
MMS3_k127_1660968_5	234267.Acid_0489	1.455e-86	292.0	COG3880@1|root,COG3880@2|Bacteria,3Y2KG@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMS3_k127_1660968_0	1128421.JAGA01000003_gene2870	0.0	1129.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
MMS3_k127_1660968_2	1128421.JAGA01000003_gene2871	1.133e-206	651.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
MMS3_k127_1660968_11	234267.Acid_0492	3.076e-64	226.0	COG2010@1|root,COG2010@2|Bacteria,3Y3HF@57723|Acidobacteria	57723|Acidobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
MMS3_k127_1660968_8	204669.Acid345_3000	6.343e-73	250.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria,2JI6T@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMS3_k127_1660968_3	1128421.JAGA01000003_gene2874	4.371e-116	387.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1660968_19	234267.Acid_0495	7.618e-13	75.0	2EJZ3@1|root,33DPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1660968_7	886293.Sinac_3660	3.684e-77	269.0	COG1999@1|root,COG1999@2|Bacteria,2IYYD@203682|Planctomycetes	203682|Planctomycetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
MMS3_k127_1660968_4	234267.Acid_0497	1.384e-109	364.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
MMS3_k127_1660968_1	234267.Acid_0498	5.003e-279	864.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
MMS3_k127_1660968_9	234267.Acid_0499	1.289e-68	240.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
MMS3_k127_1660968_17	234267.Acid_0500	6.028e-19	89.0	2DR0H@1|root,339NS@2|Bacteria,3Y59F@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM Caa(3)-type oxidase, subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
MMS3_k127_1660968_12	861299.J421_1547	3.916e-56	207.0	COG0122@1|root,COG0122@2|Bacteria	861299.J421_1547|-	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1660968_6	1089550.ATTH01000001_gene487	6.239e-80	284.0	COG2067@1|root,COG2067@2|Bacteria,4NFFF@976|Bacteroidetes,1FIPQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
MMS3_k127_1660968_15	1037409.BJ6T_30010	9.245e-24	115.0	COG2516@1|root,COG2516@2|Bacteria,1MWZQ@1224|Proteobacteria,2TV9Z@28211|Alphaproteobacteria,3JXXY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_1692229_5	748247.AZKH_0204	7.464e-42	166.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VKYM@28216|Betaproteobacteria,2KWGC@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_1692229_1	269799.Gmet_1092	1.941e-121	399.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42S6H@68525|delta/epsilon subdivisions,2WNDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
MMS3_k127_1692229_0	243365.CV_0198	5.629e-148	481.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria,2KQTG@206351|Neisseriales	206351|Neisseriales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
MMS3_k127_1692229_8	330214.NIDE1927	2.494e-11	77.0	COG0589@1|root,COG0589@2|Bacteria,3J1A7@40117|Nitrospirae	40117|Nitrospirae	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_1692229_2	640511.BC1002_4807	7.959e-114	397.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VZU1@28216|Betaproteobacteria,1K8PQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMS3_k127_1692229_6	1158292.JPOE01000002_gene2058	1.161e-32	133.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
MMS3_k127_1692229_7	631362.Thi970DRAFT_03002	5.975e-29	131.0	COG1352@1|root,COG1352@2|Bacteria,1NQTI@1224|Proteobacteria,1T2RH@1236|Gammaproteobacteria,1WW59@135613|Chromatiales	135613|Chromatiales	NT	PFAM CheB methylesterase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10,PAS_4
MMS3_k127_1721566_34	1382359.JIAL01000001_gene941	1.122e-30	134.0	COG0489@1|root,COG0489@2|Bacteria,3Y59M@57723|Acidobacteria,2JJS6@204432|Acidobacteriia	204432|Acidobacteriia	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
MMS3_k127_1721566_8	1125863.JAFN01000001_gene473	9.653e-113	380.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
MMS3_k127_1721566_12	1158165.KB898881_gene683	1.97e-98	332.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,1WWEV@135613|Chromatiales	135613|Chromatiales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
MMS3_k127_1721566_10	443143.GM18_1643	4.762e-103	347.0	COG3146@1|root,COG3146@2|Bacteria,1QYWX@1224|Proteobacteria,43CDR@68525|delta/epsilon subdivisions,2X7PP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM FemAB-related protein, PEP-CTERM	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
MMS3_k127_1721566_14	1288826.MSNKSG1_06948	3.066e-78	285.0	COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,1RYP1@1236|Gammaproteobacteria,464GV@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Lipopolysaccharide biosynthesis protein	walW	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1721566_3	1288826.MSNKSG1_06943	6.519e-229	745.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,469ZI@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
MMS3_k127_1721566_32	234267.Acid_5013	5.741e-31	142.0	COG2192@1|root,COG2192@2|Bacteria,3Y6AX@57723|Acidobacteria	57723|Acidobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
MMS3_k127_1721566_2	1210884.HG799463_gene10303	4.959e-249	811.0	28HYP@1|root,2Z842@2|Bacteria,2IYHW@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1721566_23	1210884.HG799463_gene10300	3.875e-51	191.0	COG0110@1|root,COG0110@2|Bacteria,2IZXY@203682|Planctomycetes	203682|Planctomycetes	S	maltose O-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
MMS3_k127_1721566_30	880073.Calab_2957	9.317e-37	160.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1721566_27	338966.Ppro_2467	1.33e-41	166.0	COG1215@1|root,COG1215@2|Bacteria,1QXFV@1224|Proteobacteria,43AN7@68525|delta/epsilon subdivisions,2X62E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1721566_7	1210884.HG799463_gene10301	9.008e-119	396.0	COG0438@1|root,COG0438@2|Bacteria,2IY70@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1721566_37	319225.Plut_1797	3.444e-15	87.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4,Glycos_transf_2
MMS3_k127_1721566_31	1304275.C41B8_07472	1.91e-34	149.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,1RPTR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	exoQ	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_1721566_15	945713.IALB_1713	1.485e-75	268.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMS3_k127_1721566_25	1123278.KB893562_gene3234	2.249e-48	187.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,47KRN@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1721566_17	118005.AWNK01000006_gene1328	1.346e-70	259.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
MMS3_k127_1721566_6	1210884.HG799463_gene10013	5.104e-126	415.0	COG0438@1|root,COG0438@2|Bacteria,2IWW3@203682|Planctomycetes	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glyco_transf_4
MMS3_k127_1721566_33	1266914.ATUK01000011_gene2450	8.088e-31	135.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,1S9D2@1236|Gammaproteobacteria,1X2DR@135613|Chromatiales	135613|Chromatiales	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1721566_11	316067.Geob_2955	1.552e-100	352.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM ABC transporter	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
MMS3_k127_1721566_24	316067.Geob_2954	3.957e-49	186.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42SZT@68525|delta/epsilon subdivisions,2WPTX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	Transport permease protein	-	-	-	ko:K09688,ko:K09690	ko02010,map02010	M00249,M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.101,3.A.1.103	-	-	ABC2_membrane
MMS3_k127_1721566_20	1095769.CAHF01000010_gene1325	6.859e-62	238.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,473D4@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
MMS3_k127_1721566_19	933262.AXAM01000034_gene1565	5.128e-64	246.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2MJAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8,zinc_ribbon_4
MMS3_k127_1721566_28	1125863.JAFN01000001_gene384	6.117e-40	166.0	COG1269@1|root,COG1269@2|Bacteria,1RF6T@1224|Proteobacteria,42RED@68525|delta/epsilon subdivisions,2WNV7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM EpsI family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
MMS3_k127_1721566_21	1125863.JAFN01000001_gene383	7.709e-58	215.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	eight transmembrane protein EpsH	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
MMS3_k127_1721566_41	887062.HGR_03097	1.799e-10	72.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2WABA@28216|Betaproteobacteria,4AEMV@80864|Comamonadaceae	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
MMS3_k127_1721566_44	1122917.KB899674_gene303	0.0002579	52.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1VRG9@1239|Firmicutes,4HPFB@91061|Bacilli,26RMF@186822|Paenibacillaceae	91061|Bacilli	T	AraC family transcriptional regulator	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
MMS3_k127_1721566_16	525146.Ddes_0187	1.813e-73	263.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_1721566_42	714083.JH370377_gene1126	9.109e-09	68.0	COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria,4FNRD@85023|Microbacteriaceae	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
MMS3_k127_1721566_40	192952.MM_2394	1.98e-12	79.0	COG1396@1|root,arCOG01865@2157|Archaea,2XWHC@28890|Euryarchaeota,2NAEC@224756|Methanomicrobia	224756|Methanomicrobia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
MMS3_k127_1721566_1	518766.Rmar_0342	1.625e-250	790.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1FJVJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
MMS3_k127_1721566_36	582899.Hden_3463	7.257e-19	98.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
MMS3_k127_1721566_0	671143.DAMO_2206	2.013e-279	877.0	COG0488@1|root,COG0488@2|Bacteria,2NNP9@2323|unclassified Bacteria	2|Bacteria	S	ABC transporter	uup	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
MMS3_k127_1721566_38	234267.Acid_5514	6.439e-15	76.0	2ES60@1|root,33JQS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1721566_29	234267.Acid_5515	1.462e-39	155.0	COG1848@1|root,COG1848@2|Bacteria,3Y8JE@57723|Acidobacteria	57723|Acidobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	-
MMS3_k127_1721566_35	326427.Cagg_0303	8.013e-21	98.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
MMS3_k127_1721566_4	1267533.KB906734_gene4384	1.993e-209	663.0	COG3011@1|root,COG3011@2|Bacteria,3Y78A@57723|Acidobacteria,2JKGF@204432|Acidobacteriia	204432|Acidobacteriia	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
MMS3_k127_1721566_22	1123023.JIAI01000026_gene4352	1.967e-56	206.0	COG3836@1|root,COG3836@2|Bacteria,2HGEA@201174|Actinobacteria,4E3DC@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
MMS3_k127_1721566_26	1267535.KB906767_gene1647	2.181e-43	161.0	COG1695@1|root,COG1695@2|Bacteria,3Y4US@57723|Acidobacteria,2JJE8@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_1721566_18	1379270.AUXF01000001_gene2382	2.893e-66	241.0	COG0491@1|root,COG0491@2|Bacteria,1ZU73@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_1721566_43	204669.Acid345_4452	5.156e-05	53.0	COG0346@1|root,COG0346@2|Bacteria,3Y6UC@57723|Acidobacteria	57723|Acidobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1721566_5	204669.Acid345_1618	9.808e-153	491.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1721566_9	452637.Oter_1513	1.86e-111	382.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1721566_13	204669.Acid345_1620	4.67e-92	310.0	COG1136@1|root,COG1136@2|Bacteria,3Y4A6@57723|Acidobacteria,2JMVQ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1733381_7	1089550.ATTH01000001_gene2222	3.184e-108	361.0	COG0432@1|root,COG0432@2|Bacteria,4PE9F@976|Bacteroidetes,1FIKK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Pfam Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1733381_12	330084.JNYZ01000033_gene5642	3.559e-91	312.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DZDK@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	yajO	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
MMS3_k127_1733381_2	472759.Nhal_3091	1.558e-199	648.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1WXBI@135613|Chromatiales	135613|Chromatiales	S	oligopeptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
MMS3_k127_1733381_3	666685.R2APBS1_0163	3.768e-178	572.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1X5C0@135614|Xanthomonadales	135614|Xanthomonadales	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
MMS3_k127_1733381_10	1192124.LIG30_0064	5.631e-99	341.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2VRGQ@28216|Betaproteobacteria,1K6IJ@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_1733381_19	1541065.JRFE01000057_gene6269	1.797e-10	67.0	2DUIA@1|root,32UXB@2|Bacteria	2|Bacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
MMS3_k127_1733381_9	682795.AciX8_1434	1.414e-102	341.0	COG0413@1|root,COG0413@2|Bacteria,3Y3GX@57723|Acidobacteria,2JI6Y@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
MMS3_k127_1733381_13	926560.KE387027_gene398	1.01e-86	297.0	COG0414@1|root,COG0414@2|Bacteria,1WIB9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
MMS3_k127_1733381_14	290397.Adeh_1992	1.396e-14	81.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_1733381_17	1089550.ATTH01000001_gene756	1.016e-12	76.0	COG0589@1|root,COG0589@2|Bacteria,4PICI@976|Bacteroidetes,1FK3M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_1733381_16	1541065.JRFE01000057_gene6269	1.624e-13	78.0	2DUIA@1|root,32UXB@2|Bacteria	2|Bacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
MMS3_k127_1733381_5	1242864.D187_002505	1.182e-130	425.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,42P8U@68525|delta/epsilon subdivisions,2WTQE@28221|Deltaproteobacteria,2YZNT@29|Myxococcales	28221|Deltaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_1733381_8	909663.KI867150_gene224	4.945e-107	353.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,42RT8@68525|delta/epsilon subdivisions,2X6BE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1733381_11	1267535.KB906767_gene3357	5.242e-92	322.0	COG0842@1|root,COG0842@2|Bacteria,3Y2S4@57723|Acidobacteria,2JISC@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_1733381_6	278963.ATWD01000001_gene4653	2.618e-116	385.0	COG0672@1|root,COG0672@2|Bacteria,3Y78C@57723|Acidobacteria,2JKXR@204432|Acidobacteriia	204432|Acidobacteriia	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
MMS3_k127_1733381_15	671143.DAMO_0860	1.241e-13	75.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	glnG	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712,ko:K07714	ko02020,map02020	M00497,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_1733381_4	1125863.JAFN01000001_gene1528	6.573e-137	451.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_1733381_18	262724.TT_C0429	8.06e-11	70.0	2DUIA@1|root,32UXB@2|Bacteria,1WK6Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
MMS3_k127_1733381_20	1120963.KB894500_gene124	7.791e-10	61.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_1733381_0	478741.JAFS01000002_gene996	3.346e-259	809.0	COG0493@1|root,COG0493@2|Bacteria,46T1M@74201|Verrucomicrobia,37GUZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	-	1.3.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	M00046	R00093,R00114,R00248,R00977,R01414,R11026	RC00006,RC00010,RC00072,RC00123,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
MMS3_k127_1733381_1	478741.JAFS01000002_gene997	2.237e-221	697.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,46SAT@74201|Verrucomicrobia,37FXY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
MMS3_k127_1747324_4	667632.KB890179_gene95	1.723e-136	442.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,2W157@28216|Betaproteobacteria,1KGYB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_1747324_23	1120934.KB894432_gene6137	9.537e-47	177.0	2C73B@1|root,330Z7@2|Bacteria,2IIMQ@201174|Actinobacteria,4E6EA@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
MMS3_k127_1747324_29	1267534.KB906755_gene4131	1.696e-23	105.0	COG3801@1|root,COG3801@2|Bacteria	2|Bacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
MMS3_k127_1747324_17	344747.PM8797T_13620	8.249e-71	251.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
MMS3_k127_1747324_16	1267535.KB906767_gene5136	5.705e-73	248.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_7
MMS3_k127_1747324_18	1267535.KB906767_gene5135	5.056e-64	222.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
MMS3_k127_1747324_1	234267.Acid_5749	6.984e-201	656.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
MMS3_k127_1747324_33	1194972.MVAC_12491	4.049e-15	78.0	2EE1U@1|root,337WK@2|Bacteria,2IR2G@201174|Actinobacteria,23ACR@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
MMS3_k127_1747324_32	929556.Solca_1759	1.281e-19	93.0	2EM7W@1|root,33EX0@2|Bacteria,4P5SH@976|Bacteroidetes,1J02V@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1747324_6	1267533.KB906735_gene4979	5.845e-127	411.0	COG4270@1|root,COG4270@2|Bacteria,3Y5DS@57723|Acidobacteria	57723|Acidobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1747324_10	102129.Lepto7375DRAFT_0197	2.809e-111	369.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_1747324_22	102129.Lepto7375DRAFT_0197	1.359e-54	196.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_1747324_27	234267.Acid_6789	3.136e-32	138.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1747324_20	1179773.BN6_47750	2.174e-55	214.0	COG0500@1|root,COG2226@2|Bacteria,2IEI0@201174|Actinobacteria,4E86U@85010|Pseudonocardiales	201174|Actinobacteria	Q	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_11
MMS3_k127_1747324_30	234267.Acid_5245	2.742e-23	116.0	COG0577@1|root,COG0577@2|Bacteria,3Y6IX@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1747324_14	1267535.KB906767_gene1111	2.778e-76	269.0	COG1131@1|root,COG1131@2|Bacteria,3Y3U0@57723|Acidobacteria,2JI1V@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_1747324_31	933262.AXAM01000020_gene49	8.562e-20	90.0	COG5450@1|root,COG5450@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
MMS3_k127_1747324_24	391612.CY0110_30326	1.851e-38	150.0	COG1487@1|root,COG1487@2|Bacteria,1GMCM@1117|Cyanobacteria,3KK4K@43988|Cyanothece	1117|Cyanobacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1747324_2	234267.Acid_3470	1.541e-142	485.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1747324_25	313612.L8106_03989	1.685e-36	146.0	COG2199@1|root,COG2202@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1FZWU@1117|Cyanobacteria,1H8MG@1150|Oscillatoriales	1117|Cyanobacteria	T	GGDEF domain'	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,GGDEF,PAS_3,PAS_8,PAS_9
MMS3_k127_1747324_0	1267533.KB906736_gene1071	6.972e-261	839.0	COG0577@1|root,COG0577@2|Bacteria,3Y6B8@57723|Acidobacteria,2JK7N@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1747324_8	745411.B3C1_04575	7.175e-118	403.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1J58C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2939 Carboxypeptidase C (cathepsin A)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
MMS3_k127_1747324_15	234267.Acid_7212	2.664e-73	279.0	COG0346@1|root,COG0346@2|Bacteria,3Y6UC@57723|Acidobacteria	57723|Acidobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1747324_28	1267533.KB906740_gene153	2.873e-26	124.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
MMS3_k127_1747324_34	1340493.JNIF01000003_gene3658	8.369e-07	60.0	COG1240@1|root,COG1240@2|Bacteria,3Y474@57723|Acidobacteria	57723|Acidobacteria	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
MMS3_k127_1747324_13	204669.Acid345_4452	1.142e-84	295.0	COG0346@1|root,COG0346@2|Bacteria,3Y6UC@57723|Acidobacteria	57723|Acidobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1747324_11	1267533.KB906736_gene1339	1.292e-103	343.0	COG0500@1|root,COG2226@2|Bacteria,3Y4B3@57723|Acidobacteria,2JJG1@204432|Acidobacteriia	204432|Acidobacteriia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_1747324_9	1267533.KB906736_gene1337	6.051e-116	382.0	COG4977@1|root,COG4977@2|Bacteria,3Y77K@57723|Acidobacteria,2JP14@204432|Acidobacteriia	204432|Acidobacteriia	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
MMS3_k127_1747324_12	1123054.KB907705_gene2521	7.797e-86	295.0	COG3468@1|root,COG3468@2|Bacteria,1MXH3@1224|Proteobacteria,1SF17@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	Nidogen-like	-	-	-	-	-	-	-	-	-	-	-	-	NIDO,VPEP
MMS3_k127_1747324_7	234267.Acid_7212	1.084e-125	418.0	COG0346@1|root,COG0346@2|Bacteria,3Y6UC@57723|Acidobacteria	57723|Acidobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1747324_21	1298858.AUEL01000011_gene5524	4.384e-55	201.0	COG2020@1|root,COG2020@2|Bacteria,1MXP9@1224|Proteobacteria,2U2A4@28211|Alphaproteobacteria,43MDZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
MMS3_k127_1747324_3	1379270.AUXF01000002_gene1134	2.626e-138	468.0	COG2091@1|root,COG2091@2|Bacteria,1ZU9H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1747324_26	1267535.KB906767_gene1775	9.166e-35	151.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050,Stig1,ZU5
MMS3_k127_1747324_5	269084.syc1098_d	1.473e-127	418.0	COG0502@1|root,COG0502@2|Bacteria,1G3B8@1117|Cyanobacteria,1GYVW@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.bioB	BATS,Radical_SAM
MMS3_k127_1747324_19	443255.SCLAV_0530	2.181e-62	224.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	bioF	-	2.3.1.47,6.2.1.14	ko:K00652,ko:K01906	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03209,R03210,R10124	RC00004,RC00014,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_1751568_4	929556.Solca_3122	7.709e-11	66.0	2C19F@1|root,32ZRH@2|Bacteria,4NUG5@976|Bacteroidetes,1IYGV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1751568_2	1499967.BAYZ01000009_gene5328	1.035e-39	169.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
MMS3_k127_1751568_1	682795.AciX8_3222	7.593e-65	236.0	COG1723@1|root,COG1723@2|Bacteria,3Y43W@57723|Acidobacteria,2JMAA@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1751568_0	429009.Adeg_0526	1.759e-145	476.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMS3_k127_1751568_3	449447.MAE_44440	3.476e-13	71.0	COG3729@1|root,COG3729@2|Bacteria,1G86R@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Stress-induced bacterial acidophilic repeat motif	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
MMS3_k127_1754330_7	269799.Gmet_0815	2.061e-50	193.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,43SP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
MMS3_k127_1754330_5	344747.PM8797T_25126	4.943e-60	231.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMS3_k127_1754330_3	1123024.AUII01000015_gene3725	1.125e-113	383.0	COG0154@1|root,COG0154@2|Bacteria,2GN7F@201174|Actinobacteria,4DZAM@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_1754330_2	1051632.TPY_1624	2.717e-140	458.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,247Q5@186801|Clostridia	186801|Clostridia	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12,2.3.1.168,2.3.1.61	ko:K00627,ko:K00658,ko:K09699	ko00010,ko00020,ko00280,ko00310,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00310,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036,M00307	R00209,R02569,R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02742,RC02833,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,CMD,E3_binding
MMS3_k127_1754330_0	1128421.JAGA01000003_gene3230	0.0	1021.0	COG0567@1|root,COG0567@2|Bacteria,2NQJV@2323|unclassified Bacteria	2|Bacteria	C	Dehydrogenase E1 component	sucA	GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c,iSSON_1240.SSON_0677,iYL1228.KPN_00732	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
MMS3_k127_1754330_6	1267534.KB906755_gene4692	1.088e-59	229.0	COG0642@1|root,COG2205@2|Bacteria	1267534.KB906755_gene4692|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1754330_4	1382356.JQMP01000003_gene1741	2.787e-75	259.0	COG5553@1|root,COG5553@2|Bacteria,2GBCV@200795|Chloroflexi,27YTF@189775|Thermomicrobia	189775|Thermomicrobia	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1754330_1	1121104.AQXH01000001_gene2187	7.706e-149	488.0	COG4447@1|root,COG4447@2|Bacteria,4NK5F@976|Bacteroidetes,1IWI3@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1795808_5	204669.Acid345_2082	8.007e-108	357.0	COG1968@1|root,COG1968@2|Bacteria,3Y2N3@57723|Acidobacteria,2JI1A@204432|Acidobacteriia	204432|Acidobacteriia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
MMS3_k127_1795808_2	204669.Acid345_2710	9.179e-127	421.0	COG0535@1|root,COG0641@1|root,COG0535@2|Bacteria,COG0641@2|Bacteria,3Y2KT@57723|Acidobacteria,2JIDX@204432|Acidobacteriia	204432|Acidobacteriia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
MMS3_k127_1795808_1	240015.ACP_2718	1.394e-270	842.0	COG3511@1|root,COG3511@2|Bacteria,3Y2N8@57723|Acidobacteria,2JIT8@204432|Acidobacteriia	204432|Acidobacteriia	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
MMS3_k127_1795808_14	234267.Acid_7218	2.212e-43	164.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_1795808_3	1380347.JNII01000009_gene1994	3.016e-120	411.0	COG1529@1|root,COG1529@2|Bacteria,2GIY7@201174|Actinobacteria,4ESUJ@85013|Frankiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2,Fer2,Fer2_2
MMS3_k127_1795808_8	864069.MicloDRAFT_00035320	1.307e-90	313.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,2TR0R@28211|Alphaproteobacteria,1JRDJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EGP	PFAM Major Facilitator Superfamily	ynfM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1,Sugar_tr
MMS3_k127_1795808_13	1121374.KB891578_gene3240	2.622e-48	180.0	28PFD@1|root,2ZC6I@2|Bacteria,1R8PT@1224|Proteobacteria,1S49D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1795808_15	366602.Caul_2927	9.022e-42	160.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2UI5V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
MMS3_k127_1795808_6	1122223.KB890687_gene2678	5.812e-103	347.0	COG1975@1|root,COG1975@2|Bacteria,1WIZE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	XdhC Rossmann domain	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
MMS3_k127_1795808_16	1288484.APCS01000156_gene1857	6.326e-34	138.0	COG2068@1|root,COG2068@2|Bacteria	2|Bacteria	NU	MobA-Related Protein	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
MMS3_k127_1795808_7	1122221.JHVI01000020_gene1123	7.749e-94	316.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMS3_k127_1795808_10	644966.Tmar_1491	3.12e-68	250.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,3WDUM@538999|Clostridiales incertae sedis	186801|Clostridia	C	COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_1795808_0	867903.ThesuDRAFT_01358	0.0	1114.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
MMS3_k127_1795808_12	319795.Dgeo_0213	1.281e-48	178.0	COG3427@1|root,COG3427@2|Bacteria,1WMJ8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	carbon monoxide dehydrogenase	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
MMS3_k127_1795808_9	604331.AUHY01000019_gene1846	7.189e-70	256.0	COG1975@1|root,COG1975@2|Bacteria	2|Bacteria	O	molybdopterin cofactor binding	coxF	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
MMS3_k127_1795808_4	926554.KI912655_gene4621	3.434e-120	402.0	COG0714@1|root,COG0714@2|Bacteria,1WMDH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
MMS3_k127_1795808_11	1540221.JQNI01000002_gene2012	1.807e-66	242.0	COG3552@1|root,COG3552@2|Bacteria,1WKW5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
MMS3_k127_1800238_2	926550.CLDAP_00120	2.74e-134	446.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
MMS3_k127_1800238_8	204669.Acid345_1206	3.167e-56	201.0	COG0663@1|root,COG0663@2|Bacteria,3Y4A5@57723|Acidobacteria,2JJ1R@204432|Acidobacteriia	204432|Acidobacteriia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
MMS3_k127_1800238_6	671143.DAMO_1182	1.264e-100	330.0	COG0717@1|root,COG0717@2|Bacteria,2NQ5G@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
MMS3_k127_1800238_11	1121324.CLIT_5c00920	2.941e-10	66.0	2DNS1@1|root,32YVX@2|Bacteria,1VEGC@1239|Firmicutes,24SFG@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
MMS3_k127_1800238_9	316067.Geob_3546	1.559e-52	189.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,43UWR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
MMS3_k127_1800238_4	1267534.KB906754_gene3139	1.094e-131	425.0	COG0074@1|root,COG0074@2|Bacteria,3Y3UX@57723|Acidobacteria,2JHSN@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
MMS3_k127_1800238_1	1267535.KB906767_gene3553	1.437e-163	526.0	COG0045@1|root,COG0045@2|Bacteria,3Y36X@57723|Acidobacteria,2JHR1@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
MMS3_k127_1800238_10	1353529.M899_2136	2.291e-44	173.0	2CAZH@1|root,2Z7RU@2|Bacteria,1N3AE@1224|Proteobacteria,42UBH@68525|delta/epsilon subdivisions,2MT2C@213481|Bdellovibrionales,2WQ56@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
MMS3_k127_1800238_0	1382359.JIAL01000001_gene2876	1.4e-322	1010.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria,2JIC4@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_1800238_5	1123508.JH636439_gene1816	2.699e-102	349.0	COG0479@1|root,COG0479@2|Bacteria,2IX7J@203682|Planctomycetes	203682|Planctomycetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
MMS3_k127_1800238_3	240015.ACP_0090	1.642e-133	432.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria,2JII1@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMS3_k127_1800238_7	247490.KSU1_D0121	1.288e-71	244.0	COG0538@1|root,COG0538@2|Bacteria,2J51C@203682|Planctomycetes	203682|Planctomycetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
MMS3_k127_1810250_30	204669.Acid345_3251	6.521e-135	437.0	COG1294@1|root,COG1294@2|Bacteria,3Y3UT@57723|Acidobacteria,2JIRG@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
MMS3_k127_1810250_11	204669.Acid345_3252	1.187e-195	620.0	COG1271@1|root,COG1271@2|Bacteria,3Y44V@57723|Acidobacteria,2JJ96@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
MMS3_k127_1810250_123	351607.Acel_0042	5.065e-43	166.0	COG1765@1|root,COG1765@2|Bacteria,2HA74@201174|Actinobacteria	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS3_k127_1810250_68	886293.Sinac_0625	8.734e-91	317.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	2|Bacteria	S	PFAM Peptidase M16 inactive domain	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1810250_28	1191523.MROS_1496	3.771e-137	453.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1810250_51	1162668.LFE_1855	1.397e-113	377.0	COG0489@1|root,COG0489@2|Bacteria,3J0Z6@40117|Nitrospirae	40117|Nitrospirae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
MMS3_k127_1810250_174	301.JNHE01000030_gene661	7.384e-11	72.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,1YGXT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
MMS3_k127_1810250_172	1267535.KB906767_gene2973	6.584e-11	70.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_179	1449335.JQLG01000004_gene2185	7.132e-10	69.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,27F9S@186828|Carnobacteriaceae	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS3_k127_1810250_82	368407.Memar_1498	5.249e-72	277.0	COG0210@1|root,arCOG00802@2157|Archaea	2157|Archaea	L	UvrD REP helicase	-	-	3.6.4.12	ko:K03657,ko:K16898	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
MMS3_k127_1810250_158	593750.Metfor_1905	4.889e-22	113.0	arCOG00805@1|root,arCOG00805@2157|Archaea,2XVHZ@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3857 ATP-dependent nuclease, subunit B	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
MMS3_k127_1810250_150	234267.Acid_1793	6.554e-26	114.0	2DB97@1|root,33TRP@2|Bacteria,3Y7NY@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_48	1267535.KB906767_gene4240	9.609e-115	392.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Trans_reg_C
MMS3_k127_1810250_41	204669.Acid345_3570	1.227e-117	386.0	COG1131@1|root,COG1131@2|Bacteria,3Y394@57723|Acidobacteria,2JINE@204432|Acidobacteriia	204432|Acidobacteriia	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1810250_72	204669.Acid345_3571	6.306e-85	307.0	2DC1Z@1|root,2ZCIM@2|Bacteria,3Y4F2@57723|Acidobacteria,2JJ0Y@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
MMS3_k127_1810250_62	663610.JQKO01000021_gene305	6.672e-97	322.0	29J2S@1|root,30608@2|Bacteria,1P97Y@1224|Proteobacteria,2UYZ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_45	663610.JQKO01000021_gene306	2.762e-117	382.0	2DBCM@1|root,2Z8EG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_88	663610.JQKO01000021_gene307	2.704e-66	233.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M
MMS3_k127_1810250_143	1245469.S58_47460	6.958e-30	126.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,3JQZ5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Probable molybdopterin binding domain	MA20_09420	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,NTP_transf_3
MMS3_k127_1810250_180	714961.BFZC1_02612	9.183e-10	65.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3IYII@400634|Lysinibacillus	91061|Bacilli	K	Cold-shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_1810250_117	452637.Oter_4195	1.18e-46	176.0	COG0546@1|root,COG0546@2|Bacteria,46SW1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
MMS3_k127_1810250_178	439235.Dalk_2457	5.971e-10	63.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MKYU@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_1810250_135	313612.L8106_24545	1.17e-34	139.0	COG2032@1|root,COG2032@2|Bacteria,1G9Z6@1117|Cyanobacteria,1HD5U@1150|Oscillatoriales	1117|Cyanobacteria	P	Copper/zinc superoxide dismutase (SODC)	-	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
MMS3_k127_1810250_171	243924.LT42_04240	1.909e-12	80.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RMTS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
MMS3_k127_1810250_163	1238182.C882_1749	7.117e-18	97.0	COG0500@1|root,COG0500@2|Bacteria,1QU9M@1224|Proteobacteria,2UBBM@28211|Alphaproteobacteria,2JSZ2@204441|Rhodospirillales	204441|Rhodospirillales	Q	SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
MMS3_k127_1810250_96	671143.DAMO_1600	1.267e-61	224.0	COG0613@1|root,COG0613@2|Bacteria,2NPEX@2323|unclassified Bacteria	2|Bacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
MMS3_k127_1810250_147	1121441.AUCX01000009_gene2470	8.949e-28	124.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2X5PR@28221|Deltaproteobacteria,2MBC8@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMS3_k127_1810250_130	661478.OP10G_2097	7.698e-36	141.0	COG0316@1|root,COG0316@2|Bacteria	2|Bacteria	S	protein maturation	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
MMS3_k127_1810250_8	1267535.KB906767_gene111	1.282e-225	710.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,3Y2FA@57723|Acidobacteria,2JI4J@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the reversible hydration of fumarate to (S)- malate	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
MMS3_k127_1810250_25	269799.Gmet_3082	5.157e-143	469.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2X6YF@28221|Deltaproteobacteria,43TQ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1,cNMP_binding
MMS3_k127_1810250_131	237368.SCABRO_02067	9.983e-36	154.0	COG0500@1|root,COG2226@2|Bacteria,2IZB5@203682|Planctomycetes	203682|Planctomycetes	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
MMS3_k127_1810250_93	697303.Thewi_0724	8.411e-63	226.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,42F0K@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Phosphomethylpyrimidine kinase type-1	thiD	-	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941,ko:K14153	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
MMS3_k127_1810250_138	292459.STH3180	3.836e-33	138.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
MMS3_k127_1810250_165	324602.Caur_1871	1.666e-15	79.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77,2.8.1.12,4.6.1.17	ko:K03636,ko:K03637,ko:K03752,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11372,R11581	RC02507,RC03425	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775	ThiS
MMS3_k127_1810250_24	1382359.JIAL01000001_gene1363	2.698e-143	464.0	COG0216@1|root,COG0216@2|Bacteria,3Y2N9@57723|Acidobacteria,2JHYH@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMS3_k127_1810250_99	240015.ACP_2650	1.164e-58	214.0	COG2890@1|root,COG2890@2|Bacteria,3Y4KU@57723|Acidobacteria,2JJCF@204432|Acidobacteriia	204432|Acidobacteriia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
MMS3_k127_1810250_115	1042375.AFPL01000018_gene310	5.109e-47	171.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,467BG@72275|Alteromonadaceae	1236|Gammaproteobacteria	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hinT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
MMS3_k127_1810250_103	237368.SCABRO_02963	1.369e-53	199.0	COG3375@1|root,COG3375@2|Bacteria,2J14I@203682|Planctomycetes	203682|Planctomycetes	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_168	321332.CYB_2318	8.77e-15	87.0	COG1011@1|root,COG1011@2|Bacteria,1G51I@1117|Cyanobacteria,1H0H2@1129|Synechococcus	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
MMS3_k127_1810250_85	926550.CLDAP_35400	6.468e-71	258.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1810250_52	479434.Sthe_2769	2.452e-111	376.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia	189775|Thermomicrobia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1810250_1	1125863.JAFN01000001_gene2522	0.0	1050.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
MMS3_k127_1810250_146	1232410.KI421420_gene3159	4.438e-28	126.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,43UXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
MMS3_k127_1810250_76	429009.Adeg_1604	2.538e-81	286.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42F72@68295|Thermoanaerobacterales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMS3_k127_1810250_137	1120980.JQKH01000116_gene2006	1.901e-33	135.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,2KR33@206351|Neisseriales	206351|Neisseriales	L	Psort location Cytoplasmic, score 8.96	mutT	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
MMS3_k127_1810250_69	234267.Acid_1085	8.101e-87	296.0	COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
MMS3_k127_1810250_2	1267533.KB906733_gene3579	5.74e-283	892.0	COG0466@1|root,COG0466@2|Bacteria,3Y2QB@57723|Acidobacteria,2JHMJ@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMS3_k127_1810250_164	289376.THEYE_A1545	2.663e-16	87.0	COG1734@1|root,COG1734@2|Bacteria,3J0R1@40117|Nitrospirae	40117|Nitrospirae	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
MMS3_k127_1810250_145	290397.Adeh_3592	1.203e-28	128.0	2DKHM@1|root,309GY@2|Bacteria,1RFJ6@1224|Proteobacteria,43BG3@68525|delta/epsilon subdivisions,2X6UE@28221|Deltaproteobacteria,2Z3CV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_173	515635.Dtur_0904	6.834e-11	71.0	2EGFY@1|root,33A7X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_160	401053.AciPR4_0433	2.765e-20	93.0	COG0227@1|root,COG0227@2|Bacteria,3Y5KC@57723|Acidobacteria,2JJYY@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
MMS3_k127_1810250_121	243231.GSU2235	4.497e-45	166.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria,43V3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
MMS3_k127_1810250_6	240015.ACP_2888	3.736e-252	796.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria,2JIN0@204432|Acidobacteriia	204432|Acidobacteriia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
MMS3_k127_1810250_177	1267535.KB906767_gene4744	1.845e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,3Y3N5@57723|Acidobacteria,2JISD@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
MMS3_k127_1810250_161	1382359.JIAL01000001_gene982	4.303e-18	92.0	COG0848@1|root,COG0848@2|Bacteria,3Y5AP@57723|Acidobacteria,2JJQV@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
MMS3_k127_1810250_151	1382359.JIAL01000001_gene983	1.081e-24	108.0	COG0848@1|root,COG0848@2|Bacteria,3Y4TE@57723|Acidobacteria,2JJKY@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
MMS3_k127_1810250_92	1267535.KB906767_gene4741	5.157e-64	227.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria,2JI9T@204432|Acidobacteriia	204432|Acidobacteriia	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
MMS3_k127_1810250_144	1047013.AQSP01000079_gene2043	7.588e-30	128.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
MMS3_k127_1810250_0	1254432.SCE1572_06975	0.0	1124.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
MMS3_k127_1810250_120	289376.THEYE_A1869	1.752e-45	174.0	COG2928@1|root,COG2928@2|Bacteria,3J0R2@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
MMS3_k127_1810250_97	1232410.KI421418_gene2299	1.857e-59	220.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	SecD/SecF GG Motif	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMS3_k127_1810250_34	204669.Acid345_0146	1.781e-131	436.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria,2JHJC@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMS3_k127_1810250_162	706587.Desti_4871	6.975e-18	87.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2MQKT@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
MMS3_k127_1810250_31	641491.DND132_0618	2.223e-133	436.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,2M9GZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
MMS3_k127_1810250_42	1382356.JQMP01000004_gene466	1.264e-117	391.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
MMS3_k127_1810250_154	945713.IALB_2607	1.517e-23	117.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,TPR_8
MMS3_k127_1810250_108	483219.LILAB_31320	2.669e-51	206.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
MMS3_k127_1810250_33	204669.Acid345_2187	2.372e-132	432.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria,2JITG@204432|Acidobacteriia	204432|Acidobacteriia	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_1810250_95	671143.DAMO_2311	8.31e-62	220.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
MMS3_k127_1810250_57	204669.Acid345_4701	2.211e-102	346.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria,2JI81@204432|Acidobacteriia	204432|Acidobacteriia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMS3_k127_1810250_79	330214.NIDE1579	1.401e-75	271.0	COG0285@1|root,COG0285@2|Bacteria,3J0I6@40117|Nitrospirae	40117|Nitrospirae	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
MMS3_k127_1810250_100	1047013.AQSP01000138_gene1041	3.207e-58	228.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659	-	ko:K04744,ko:K09774,ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2,1.B.42.1	-	iAF987.Gmet_2474,iECO111_1330.ECO111_4695,iECSF_1327.ECSF_3725,iEcSMS35_1347.EcSMS35_4260	KdgM,OstA,OstA_2,OstA_C
MMS3_k127_1810250_50	368407.Memar_0186	3.54e-114	405.0	COG1088@1|root,arCOG01371@2157|Archaea,2XUZX@28890|Euryarchaeota,2N94H@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_1810250_86	324057.Pjdr2_3512	8.016e-69	246.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4HF5Y@91061|Bacilli,275YJ@186822|Paenibacillaceae	91061|Bacilli	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_1810250_102	3641.EOY14513	1.085e-55	211.0	COG0451@1|root,KOG1502@2759|Eukaryota,37JYY@33090|Viridiplantae,3G71H@35493|Streptophyta	35493|Streptophyta	V	Male sterility protein	-	-	1.1.1.354	ko:K15891	ko00900,ko00909,ko01130,map00900,map00909,map01130	-	R10412	RC00649	ko00000,ko00001,ko01000	-	-	-	Epimerase
MMS3_k127_1810250_175	1123242.JH636434_gene4146	1.102e-10	75.0	COG0170@1|root,COG0170@2|Bacteria,2J1H5@203682|Planctomycetes	203682|Planctomycetes	I	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_153	180281.CPCC7001_1002	3.548e-24	119.0	COG1836@1|root,COG1836@2|Bacteria,1G07R@1117|Cyanobacteria,22SAI@167375|Cyanobium	1117|Cyanobacteria	S	Integral membrane protein DUF92	-	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	DUF92
MMS3_k127_1810250_152	585423.KR49_13170	1.292e-24	115.0	COG0382@1|root,COG0382@2|Bacteria,1G2BD@1117|Cyanobacteria,1GZ5B@1129|Synechococcus	1117|Cyanobacteria	H	Chlorophyll synthase, ChlG	chlG	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	iJN678.chlG	UbiA
MMS3_k127_1810250_84	861299.J421_0728	3.427e-71	252.0	COG3315@1|root,COG3315@2|Bacteria	2|Bacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
MMS3_k127_1810250_64	1449976.KALB_5658	5.868e-95	325.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4E62V@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439,ko:K05831	ko00220,ko00300,ko01100,ko01120,ko01210,ko01230,map00220,map00300,map01100,map01120,map01210,map01230	M00016,M00031,M00763	R02734,R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_1810250_70	867903.ThesuDRAFT_02358	1.144e-86	298.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3WDHP@538999|Clostridiales incertae sedis	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_1810250_27	1292035.H476_0190	5.36e-141	477.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25QH6@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
MMS3_k127_1810250_65	518766.Rmar_1819	7.929e-93	313.0	COG0501@1|root,COG0501@2|Bacteria,4PEI7@976|Bacteroidetes,1FJ5Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMS3_k127_1810250_63	1444309.JAQG01000017_gene758	3.559e-96	327.0	COG0624@1|root,COG0624@2|Bacteria,1TPSM@1239|Firmicutes,4HD69@91061|Bacilli,26TVQ@186822|Paenibacillaceae	91061|Bacilli	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_1810250_4	562970.Btus_0347	4.777e-274	856.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli,278VK@186823|Alicyclobacillaceae	91061|Bacilli	H	ThiC-associated domain	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU08790	ThiC-associated,ThiC_Rad_SAM
MMS3_k127_1810250_128	926569.ANT_02620	2.146e-38	152.0	29AZZ@1|root,2ZXYX@2|Bacteria,2G8ZX@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_49	429009.Adeg_0968	1.866e-114	388.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,42F3J@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
MMS3_k127_1810250_111	536227.CcarbDRAFT_2757	5.847e-49	181.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,36I0M@31979|Clostridiaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
MMS3_k127_1810250_16	1232410.KI421413_gene687	1.299e-183	583.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43SDW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Serine hydroxymethyltransferase	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
MMS3_k127_1810250_19	1382359.JIAL01000001_gene2668	1.236e-168	552.0	COG1199@1|root,COG1199@2|Bacteria,3Y3DN@57723|Acidobacteria,2JHJZ@204432|Acidobacteriia	204432|Acidobacteriia	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
MMS3_k127_1810250_170	1173029.JH980292_gene1820	1.344e-12	81.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1H9PH@1150|Oscillatoriales	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_1,TPR_11,TPR_2,TPR_8
MMS3_k127_1810250_109	671143.DAMO_2290	3.035e-51	191.0	COG0325@1|root,COG0325@2|Bacteria,2NPEW@2323|unclassified Bacteria	2|Bacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
MMS3_k127_1810250_159	1144275.COCOR_04939	2.375e-20	99.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42UNA@68525|delta/epsilon subdivisions,2WQ1A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	DivIVA protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
MMS3_k127_1810250_156	479434.Sthe_1691	1.643e-22	100.0	COG1872@1|root,COG1872@2|Bacteria,2G9SM@200795|Chloroflexi,27YQ3@189775|Thermomicrobia	189775|Thermomicrobia	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
MMS3_k127_1810250_58	1121472.AQWN01000007_gene1144	4.439e-102	346.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
MMS3_k127_1810250_157	984262.SGRA_0031	3.354e-22	104.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes	976|Bacteroidetes	E	Glutamate formimidoyltransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
MMS3_k127_1810250_94	1123376.AUIU01000012_gene1496	2.176e-62	222.0	COG0681@1|root,COG0681@2|Bacteria,3J0IP@40117|Nitrospirae	40117|Nitrospirae	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
MMS3_k127_1810250_3	1382359.JIAL01000001_gene807	1.229e-282	879.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
MMS3_k127_1810250_32	240015.ACP_1789	3.515e-133	434.0	COG0372@1|root,COG0372@2|Bacteria,3Y32J@57723|Acidobacteria,2JII8@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_1810250_12	502025.Hoch_3647	2.072e-195	614.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
MMS3_k127_1810250_14	1267533.KB906733_gene3096	3.218e-186	599.0	COG1215@1|root,COG1215@2|Bacteria,3Y31I@57723|Acidobacteria,2JIKW@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
MMS3_k127_1810250_74	1125863.JAFN01000001_gene1413	8.646e-83	283.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
MMS3_k127_1810250_40	292459.STH1115	3.322e-122	425.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
MMS3_k127_1810250_56	1382359.JIAL01000001_gene1018	1.35e-102	356.0	COG0358@1|root,COG0358@2|Bacteria,3Y366@57723|Acidobacteria,2JIHT@204432|Acidobacteriia	204432|Acidobacteriia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
MMS3_k127_1810250_10	1267534.KB906754_gene3793	1.681e-201	642.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_1810250_132	204669.Acid345_4769	1.101e-35	147.0	COG1579@1|root,COG1579@2|Bacteria,3Y509@57723|Acidobacteria,2JK0Q@204432|Acidobacteriia	204432|Acidobacteriia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
MMS3_k127_1810250_126	240015.ACP_2389	7.136e-40	156.0	COG0328@1|root,COG0328@2|Bacteria,3Y4EY@57723|Acidobacteria,2JJ1U@204432|Acidobacteriia	204432|Acidobacteriia	L	Reverse transcriptase-like	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
MMS3_k127_1810250_134	626939.HMPREF9443_01631	8.806e-35	149.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4H26Q@909932|Negativicutes	909932|Negativicutes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
MMS3_k127_1810250_29	335543.Sfum_3475	1.155e-136	455.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2MRDF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_1810250_37	671143.DAMO_2292	9.602e-125	413.0	COG0206@1|root,COG0206@2|Bacteria,2NNSU@2323|unclassified Bacteria	2|Bacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMS3_k127_1810250_22	1047013.AQSP01000140_gene2472	1.857e-159	514.0	COG0849@1|root,COG0849@2|Bacteria,2NNU2@2323|unclassified Bacteria	2|Bacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
MMS3_k127_1810250_184	1133849.O3I_011735	4.722e-08	64.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4FVIV@85025|Nocardiaceae	201174|Actinobacteria	M	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
MMS3_k127_1810250_23	1125863.JAFN01000001_gene3348	4.817e-151	491.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_1810250_67	338966.Ppro_3289	1.501e-91	313.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,43UB0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
MMS3_k127_1810250_53	204669.Acid345_3630	4.343e-106	357.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
MMS3_k127_1810250_54	639030.JHVA01000001_gene1386	1.768e-104	356.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_1810250_39	1047013.AQSP01000140_gene2478	1.806e-122	409.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
MMS3_k127_1810250_77	760568.Desku_1151	2.532e-80	285.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,260TC@186807|Peptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_1810250_38	370438.PTH_1866	1.181e-124	428.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_1810250_36	204669.Acid345_3635	7.695e-131	442.0	COG0768@1|root,COG0768@2|Bacteria,3Y2XX@57723|Acidobacteria,2JHPS@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
MMS3_k127_1810250_186	404380.Gbem_0484	1.671e-06	55.0	COG3116@1|root,COG3116@2|Bacteria,1NKRZ@1224|Proteobacteria,42XDD@68525|delta/epsilon subdivisions,2WSII@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Cell division protein FtsL	ftsL	-	-	-	-	-	-	-	-	-	-	-	DivIC,FtsL
MMS3_k127_1810250_66	867903.ThesuDRAFT_01667	1.021e-91	310.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3WCDX@538999|Clostridiales incertae sedis	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
MMS3_k127_1810250_114	240015.ACP_1095	2.413e-47	173.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
MMS3_k127_1810250_59	204669.Acid345_3198	5.697e-99	337.0	COG0012@1|root,COG0012@2|Bacteria,3Y3D9@57723|Acidobacteria,2JIPE@204432|Acidobacteriia	204432|Acidobacteriia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
MMS3_k127_1810250_75	521719.ATXQ01000001_gene392	4.648e-82	283.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1YKRY@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1810250_140	1307759.JOMJ01000003_gene898	3.137e-31	130.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,42SH8@68525|delta/epsilon subdivisions,2WQ3S@28221|Deltaproteobacteria,2MC29@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
MMS3_k127_1810250_43	880072.Desac_2552	1.287e-117	400.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MQKP@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMS3_k127_1810250_125	1123388.AQWU01000034_gene1528	5.166e-40	170.0	COG0477@1|root,COG2814@2|Bacteria,1WJAR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
MMS3_k127_1810250_105	1379698.RBG1_1C00001G1850	3.815e-53	198.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMS3_k127_1810250_80	266117.Rxyl_0345	2.519e-74	261.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMS3_k127_1810250_98	660470.Theba_1523	6.621e-59	209.0	COG1704@1|root,COG1704@2|Bacteria,2GCV5@200918|Thermotogae	200918|Thermotogae	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
MMS3_k127_1810250_78	63737.Npun_R0619	4.415e-76	263.0	COG1028@1|root,COG1028@2|Bacteria,1G7G6@1117|Cyanobacteria,1HQIB@1161|Nostocales	1117|Cyanobacteria	C	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_1810250_133	861299.J421_6341	1.629e-35	141.0	COG1917@1|root,COG1917@2|Bacteria,1ZTY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_1810250_5	204669.Acid345_1786	4.429e-272	855.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria,2JHQ9@204432|Acidobacteriia	204432|Acidobacteriia	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
MMS3_k127_1810250_127	234267.Acid_4440	2.386e-39	154.0	COG1073@1|root,COG1073@2|Bacteria,3Y91X@57723|Acidobacteria	57723|Acidobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_122	644282.Deba_2882	1.738e-43	166.0	COG1309@1|root,COG1309@2|Bacteria,1MV2V@1224|Proteobacteria,42NW6@68525|delta/epsilon subdivisions,2WPIG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
MMS3_k127_1810250_7	1382304.JNIL01000001_gene3280	1.387e-232	743.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,277X4@186823|Alicyclobacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
MMS3_k127_1810250_183	158500.BV97_03851	3.653e-08	64.0	COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,2TTCT@28211|Alphaproteobacteria,2K1SM@204457|Sphingomonadales	204457|Sphingomonadales	I	Alpha beta hydrolase	-	-	-	ko:K18092	ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220	-	R05366	RC00752,RC00753	br01602,ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_1810250_118	1382306.JNIM01000001_gene3896	9.438e-46	173.0	COG2945@1|root,COG2945@2|Bacteria,2G9MQ@200795|Chloroflexi	200795|Chloroflexi	S	hydrolase of the alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
MMS3_k127_1810250_21	1382359.JIAL01000001_gene2707	2.877e-162	522.0	COG0183@1|root,COG0183@2|Bacteria,3Y2U4@57723|Acidobacteria,2JIS1@204432|Acidobacteriia	204432|Acidobacteriia	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_1810250_17	1121346.KB899809_gene3675	5.754e-178	576.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,26QCJ@186822|Paenibacillaceae	91061|Bacilli	I	acyl-CoA dehydrogenase	fadE	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1810250_139	1121904.ARBP01000003_gene6284	8.198e-33	147.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47Q5N@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
MMS3_k127_1810250_116	886293.Sinac_3837	7.684e-47	179.0	COG0637@1|root,COG0637@2|Bacteria,2J0A7@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMS3_k127_1810250_110	240292.Ava_2624	2.484e-50	196.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1HQF8@1161|Nostocales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
MMS3_k127_1810250_182	637389.Acaty_c1453	7.922e-09	66.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,2ND1R@225057|Acidithiobacillales	225057|Acidithiobacillales	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
MMS3_k127_1810250_20	525904.Tter_0214	4.861e-168	540.0	COG0624@1|root,COG0624@2|Bacteria,2NQM8@2323|unclassified Bacteria	2|Bacteria	E	Peptidase dimerisation domain	dapE	-	3.5.1.16,3.5.1.18	ko:K01436,ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_1810250_119	1382306.JNIM01000001_gene3649	1.306e-45	176.0	COG0491@1|root,COG0491@2|Bacteria,2G8W8@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_1810250_176	290397.Adeh_1557	1.157e-10	63.0	COG0695@1|root,COG0695@2|Bacteria,1P8SJ@1224|Proteobacteria,42XTX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Glutaredoxin	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
MMS3_k127_1810250_142	324602.Caur_0726	2.35e-30	124.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi,377ME@32061|Chloroflexia	32061|Chloroflexia	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
MMS3_k127_1810250_13	1313172.YM304_25950	1.206e-190	614.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CMUK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
MMS3_k127_1810250_124	671143.DAMO_2862	5.877e-41	169.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	def2	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
MMS3_k127_1810250_104	266117.Rxyl_0013	1.912e-53	195.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	nudC_1	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,Nudix_N_2
MMS3_k127_1810250_148	439493.PB7211_294	9.857e-28	126.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,2TXEY@28211|Alphaproteobacteria,4BTEZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Big_3_5
MMS3_k127_1810250_129	317936.Nos7107_1719	1.012e-36	149.0	2ERTE@1|root,33JCN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_185	717774.Marme_3765	6.64e-07	62.0	2EIP2@1|root,33CEF@2|Bacteria,1QX6D@1224|Proteobacteria,1T4Z1@1236|Gammaproteobacteria,1XQUQ@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
MMS3_k127_1810250_60	273057.SSO1863	9.46e-99	341.0	COG0477@1|root,arCOG00132@2157|Archaea,2XRR4@28889|Crenarchaeota	28889|Crenarchaeota	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1810250_9	1051632.TPY_0253	3.117e-211	669.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia	186801|Clostridia	C	L-lactate permease	glcA	-	-	ko:K02550,ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14,2.A.14.1.2	-	-	Lactate_perm
MMS3_k127_1810250_46	330214.NIDE1125	3.772e-117	389.0	COG0301@1|root,COG0301@2|Bacteria	2|Bacteria	H	tRNA thio-modification	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
MMS3_k127_1810250_83	391625.PPSIR1_11225	1.383e-71	268.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria	1224|Proteobacteria	H	squalene-associated FAD-dependent desaturase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
MMS3_k127_1810250_91	671143.DAMO_1512	2.807e-64	230.0	COG1562@1|root,COG1562@2|Bacteria,2NQ19@2323|unclassified Bacteria	2|Bacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
MMS3_k127_1810250_81	360910.BAV2417	2.93e-74	261.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,3T3CT@506|Alcaligenaceae	28216|Betaproteobacteria	I	synthase	hpnC	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
MMS3_k127_1810250_167	640132.Srot_2092	2.934e-15	82.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1810250_169	1210884.HG799470_gene14507	8.166e-14	80.0	COG0342@1|root,COG0342@2|Bacteria,2J4JC@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1810250_113	379066.GAU_0604	6.704e-48	190.0	COG2096@1|root,COG2096@2|Bacteria,1ZT4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
MMS3_k127_1810250_71	330214.NIDE1914	1.911e-85	302.0	COG1194@1|root,COG1194@2|Bacteria,3J160@40117|Nitrospirae	40117|Nitrospirae	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_1810250_149	330214.NIDE1915	8.176e-27	116.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	mutY	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX,NUDIX_4
MMS3_k127_1810250_112	378806.STAUR_1528	6.959e-49	190.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
MMS3_k127_1810250_136	1122603.ATVI01000005_gene3156	3.788e-34	150.0	COG1073@1|root,COG1073@2|Bacteria,1R67P@1224|Proteobacteria,1S4Y1@1236|Gammaproteobacteria,1X5BM@135614|Xanthomonadales	135614|Xanthomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,Hydrolase_4
MMS3_k127_1810250_18	1120949.KB903295_gene2218	9.136e-169	546.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
MMS3_k127_1810250_55	204669.Acid345_4631	7.448e-104	357.0	COG0577@1|root,COG0577@2|Bacteria,3Y3X9@57723|Acidobacteria,2JHKJ@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1810250_61	204669.Acid345_4630	7.705e-98	334.0	COG0577@1|root,COG0577@2|Bacteria,3Y2IG@57723|Acidobacteria,2JHUY@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1810250_47	204669.Acid345_3531	7.11e-116	389.0	COG0845@1|root,COG0845@2|Bacteria,3Y2F6@57723|Acidobacteria,2JI56@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
MMS3_k127_1810250_181	349521.HCH_06864	6.142e-09	70.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S3GK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	FHA Domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
MMS3_k127_1810250_101	1125863.JAFN01000001_gene1846	2.46e-56	211.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_1810250_155	1267535.KB906767_gene3024	1.77e-23	104.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	frzZ	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMS3_k127_1810250_87	243274.THEMA_02935	8.667e-69	250.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0356	ACT,ACT_4,PALP
MMS3_k127_1810250_107	204669.Acid345_4392	1.652e-52	200.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
MMS3_k127_1810250_15	234267.Acid_3778	1.373e-184	604.0	COG0577@1|root,COG0577@2|Bacteria,3Y3Z1@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_1810250_90	1267535.KB906767_gene5044	6.342e-65	231.0	COG4221@1|root,COG4221@2|Bacteria,3Y4DX@57723|Acidobacteria	57723|Acidobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_1810250_166	1122176.KB903554_gene4012	1.679e-15	87.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1IP11@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMS3_k127_1810250_141	401053.AciPR4_1520	1.104e-30	130.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1810250_89	483219.LILAB_29215	1.034e-65	231.0	COG0321@1|root,COG1051@1|root,COG0321@2|Bacteria,COG1051@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WPRF@28221|Deltaproteobacteria,2YVCE@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
MMS3_k127_1810250_35	1340493.JNIF01000004_gene487	3.365e-131	435.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_1810250_26	378806.STAUR_4671	5.71e-142	464.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_1810250_44	1232437.KL661969_gene4957	2.381e-117	396.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_1810250_106	243231.GSU1446	4.648e-53	205.0	COG0641@1|root,COG0641@2|Bacteria,1R7G1@1224|Proteobacteria,42PI5@68525|delta/epsilon subdivisions,2WIK2@28221|Deltaproteobacteria,43T2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
MMS3_k127_1816081_12	1125973.JNLC01000010_gene1163	3.729e-31	138.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TS14@28211|Alphaproteobacteria,3JQM3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	MA20_19540	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_1816081_5	502025.Hoch_4278	4.207e-59	227.0	COG0642@1|root,COG2205@2|Bacteria	502025.Hoch_4278|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1816081_14	1267533.KB906734_gene4351	1.687e-20	94.0	COG0776@1|root,COG0776@2|Bacteria,3Y5E1@57723|Acidobacteria,2JJN0@204432|Acidobacteriia	204432|Acidobacteriia	L	Bacterial DNA-binding protein	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMS3_k127_1816081_9	391625.PPSIR1_04683	6.349e-45	165.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2Z0PZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
MMS3_k127_1816081_13	1267535.KB906767_gene291	1.809e-21	97.0	COG1193@1|root,COG1193@2|Bacteria,3Y8PZ@57723|Acidobacteria	57723|Acidobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
MMS3_k127_1816081_6	1121468.AUBR01000052_gene1608	6.187e-59	232.0	COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,25C98@186801|Clostridia,42F1Q@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883,Helicase_C,SNF2_N
MMS3_k127_1816081_3	1330700.JQNC01000003_gene609	3.768e-90	334.0	COG1002@1|root,COG1002@2|Bacteria,1WIE6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase
MMS3_k127_1816081_1	309801.trd_A0629	4.395e-132	437.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
MMS3_k127_1816081_0	324602.Caur_3201	0.0	1248.0	COG0243@1|root,COG0243@2|Bacteria,2G5ZB@200795|Chloroflexi,37670@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMS3_k127_1816081_15	1302286.BAOT01000035_gene1481	8.862e-09	67.0	COG4272@1|root,COG4272@2|Bacteria,1VGWJ@1239|Firmicutes,4HQ1Q@91061|Bacilli,3F7G8@33958|Lactobacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
MMS3_k127_1816081_7	264732.Moth_0371	5.859e-54	200.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,249II@186801|Clostridia,42FVW@68295|Thermoanaerobacterales	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_1816081_2	1303518.CCALI_01626	1.16e-102	348.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	yrkH	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
MMS3_k127_1816081_4	251221.35210936	4.058e-66	248.0	COG1574@1|root,COG1574@2|Bacteria,1G40U@1117|Cyanobacteria	1117|Cyanobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_1816081_11	1340493.JNIF01000003_gene1957	2.958e-34	141.0	2DB97@1|root,32TX2@2|Bacteria,3Y59S@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1816081_8	234267.Acid_2432	7.316e-47	177.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
MMS3_k127_1816081_10	861299.J421_3902	1.567e-42	171.0	COG5587@1|root,COG5587@2|Bacteria,1ZTH8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
MMS3_k127_1841676_10	1041930.Mtc_1618	3.423e-14	73.0	COG3350@1|root,arCOG04507@2157|Archaea	2157|Archaea	P	PFAM YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
MMS3_k127_1841676_3	1340493.JNIF01000004_gene459	1.526e-91	321.0	COG1538@1|root,COG1538@2|Bacteria,3Y6KZ@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
MMS3_k127_1841676_1	1267535.KB906767_gene546	6.655e-168	539.0	COG2132@1|root,COG2132@2|Bacteria,3Y5PP@57723|Acidobacteria,2JK1U@204432|Acidobacteriia	204432|Acidobacteriia	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
MMS3_k127_1841676_7	278963.ATWD01000001_gene4390	1.399e-42	168.0	COG1999@1|root,COG1999@2|Bacteria,3Y5CC@57723|Acidobacteria,2JHX0@204432|Acidobacteriia	204432|Acidobacteriia	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
MMS3_k127_1841676_11	1198114.AciX9_2169	8.917e-11	74.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
MMS3_k127_1841676_9	67373.JOBF01000002_gene1249	1.721e-18	99.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,PD40,PQQ_2
MMS3_k127_1841676_6	639030.JHVA01000001_gene2789	8.625e-50	184.0	COG5516@1|root,COG5516@2|Bacteria,3Y5TP@57723|Acidobacteria,2JNQF@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
MMS3_k127_1841676_2	234267.Acid_5969	5.518e-159	514.0	COG0076@1|root,COG0076@2|Bacteria,3Y365@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
MMS3_k127_1841676_5	420662.Mpe_A3610	1.25e-53	192.0	2AXM7@1|root,31PMG@2|Bacteria,1RIYV@1224|Proteobacteria,2VUMG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1841676_4	420662.Mpe_A3611	1.718e-75	263.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,2WAA3@28216|Betaproteobacteria,1KNX1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1841676_12	598659.NAMH_1184	2.043e-08	58.0	2AY0S@1|root,31Q2B@2|Bacteria,1QMQY@1224|Proteobacteria,42SY0@68525|delta/epsilon subdivisions,2YPGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
MMS3_k127_1841676_0	1185652.USDA257_c39410	8.177e-315	981.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR56@28211|Alphaproteobacteria,4B7DZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	E1-E2 ATPase	cadA	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
MMS3_k127_1841676_8	211586.SO_3857	2.279e-22	106.0	COG0671@1|root,COG0671@2|Bacteria,1N3TP@1224|Proteobacteria,1SADV@1236|Gammaproteobacteria,2QARH@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
MMS3_k127_1884886_13	635013.TherJR_2333	6.755e-104	354.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,26466@186807|Peptococcaceae	186801|Clostridia	T	signal transduction protein containing EAL and modified HD-GYP	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
MMS3_k127_1884886_0	1123278.KB893444_gene1718	0.0	1254.0	COG4447@1|root,COG4447@2|Bacteria,4NK01@976|Bacteroidetes,47NT3@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1884886_37	443143.GM18_0480	1.293e-05	55.0	COG2885@1|root,COG3047@1|root,COG2885@2|Bacteria,COG3047@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2WVVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA
MMS3_k127_1884886_15	1128421.JAGA01000002_gene1518	1.078e-94	325.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
MMS3_k127_1884886_10	1117647.M5M_17220	1.24e-128	422.0	COG0520@1|root,COG0520@2|Bacteria,1PJFE@1224|Proteobacteria,1RRJK@1236|Gammaproteobacteria,1JA4W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0520 Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_1884886_17	857087.Metme_4431	6.617e-72	257.0	COG2203@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,1RZAF@1236|Gammaproteobacteria,1XFZE@135618|Methylococcales	1236|Gammaproteobacteria	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA_2,PAS_4,PAS_9
MMS3_k127_1884886_39	68194.JNXR01000045_gene1300	0.0005726	51.0	COG2771@1|root,COG2771@2|Bacteria,2IJPU@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
MMS3_k127_1884886_26	1173027.Mic7113_5147	3.853e-30	133.0	COG0642@1|root,COG2205@2|Bacteria,1G0TS@1117|Cyanobacteria,1H8JZ@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
MMS3_k127_1884886_30	350054.Mflv_4766	7.271e-17	88.0	COG2604@1|root,COG2604@2|Bacteria,2ICIC@201174|Actinobacteria,235G1@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
MMS3_k127_1884886_27	1041139.KB902724_gene3929	6.097e-28	129.0	COG4692@1|root,COG4692@2|Bacteria,1Q1EG@1224|Proteobacteria,2TUY5@28211|Alphaproteobacteria,4B94N@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
MMS3_k127_1884886_36	1380356.JNIK01000019_gene453	1.828e-07	63.0	2E77D@1|root,331R6@2|Bacteria,2GU4N@201174|Actinobacteria,4ETHG@85013|Frankiales	201174|Actinobacteria	S	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
MMS3_k127_1884886_14	1123242.JH636436_gene432	2.322e-96	323.0	COG1352@1|root,COG1352@2|Bacteria,2IYFW@203682|Planctomycetes	203682|Planctomycetes	NT	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
MMS3_k127_1884886_11	1123242.JH636434_gene4225	2.146e-128	421.0	COG2201@1|root,COG2201@2|Bacteria,2IX6F@203682|Planctomycetes	203682|Planctomycetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
MMS3_k127_1884886_23	886293.Sinac_3686	1.905e-36	144.0	COG2199@1|root,COG3706@2|Bacteria,2J0C7@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
MMS3_k127_1884886_21	1300345.LF41_2785	3.216e-50	197.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1X4P8@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
MMS3_k127_1884886_5	1123242.JH636434_gene4230	1.151e-198	644.0	COG0840@1|root,COG0840@2|Bacteria,2IXQA@203682|Planctomycetes	203682|Planctomycetes	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Globin,HAMP,MCPsignal,PAS_3,PAS_4,PAS_9
MMS3_k127_1884886_22	1123242.JH636434_gene4224	2.092e-49	181.0	COG0835@1|root,COG0835@2|Bacteria,2IZN1@203682|Planctomycetes	203682|Planctomycetes	NT	CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
MMS3_k127_1884886_4	1122165.AUHS01000008_gene1051	1.853e-202	661.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1JDBT@118969|Legionellales	118969|Legionellales	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,HATPase_c,Hpt
MMS3_k127_1884886_32	204669.Acid345_1530	2.024e-11	72.0	COG1406@1|root,COG1406@2|Bacteria	2|Bacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
MMS3_k127_1884886_38	1382359.JIAL01000001_gene1291	0.0002194	53.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1884886_25	330214.NIDE4245	9.46e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,3J1A1@40117|Nitrospirae	40117|Nitrospirae	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1884886_20	671143.DAMO_1931	3.492e-53	206.0	COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_1884886_19	234267.Acid_4152	5.738e-61	226.0	COG0845@1|root,COG0845@2|Bacteria,3Y4YK@57723|Acidobacteria	57723|Acidobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMS3_k127_1884886_1	234267.Acid_4151	0.0	1176.0	COG0841@1|root,COG0841@2|Bacteria,3Y2SK@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMS3_k127_1884886_34	1122221.JHVI01000012_gene923	1.332e-08	68.0	COG0589@1|root,COG0589@2|Bacteria,1WMQ9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_1884886_31	83406.HDN1F_09590	7.812e-16	83.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,1J7D9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
MMS3_k127_1884886_24	1238182.C882_0632	2.716e-35	139.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2UAEV@28211|Alphaproteobacteria,2JSMW@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
MMS3_k127_1884886_3	1267535.KB906767_gene656	7.272e-238	745.0	COG1032@1|root,COG1032@2|Bacteria,3Y2FN@57723|Acidobacteria,2JI6W@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_1884886_33	1449347.JQLN01000005_gene4186	3.357e-11	74.0	COG1670@1|root,COG1670@2|Bacteria,2I18Y@201174|Actinobacteria,2M34U@2063|Kitasatospora	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_1884886_12	1123072.AUDH01000005_gene1737	3.764e-106	363.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSZ8@28211|Alphaproteobacteria,2JWD7@204441|Rhodospirillales	204441|Rhodospirillales	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_1884886_18	1121441.AUCX01000005_gene1320	1.469e-62	224.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,2M80V@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890,ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
MMS3_k127_1884886_28	1128421.JAGA01000002_gene435	7.866e-28	128.0	COG2340@1|root,COG3103@1|root,COG2340@2|Bacteria,COG4991@2|Bacteria,2NQ03@2323|unclassified Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	CAP,Glyco_hydro_99,SH3_3,SH3_4
MMS3_k127_1884886_6	479434.Sthe_3255	4.749e-188	598.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	200795|Chloroflexi	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_1884886_9	644966.Tmar_1752	1.135e-140	458.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,3WD6V@538999|Clostridiales incertae sedis	186801|Clostridia	C	acyl-CoA transferase carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
MMS3_k127_1884886_16	644966.Tmar_1751	2.01e-92	310.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3WCJ4@538999|Clostridiales incertae sedis	186801|Clostridia	I	PFAM Enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715,ko:K13767	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_1884886_29	29581.BW37_04425	1.12e-19	89.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria,2WCK9@28216|Betaproteobacteria,477U2@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1884886_35	522306.CAP2UW1_4074	3.949e-08	68.0	COG2331@1|root,COG2331@2|Bacteria,1PVEY@1224|Proteobacteria,2VYJG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_1884886_2	379066.GAU_2315	6.065e-246	790.0	COG0551@1|root,COG0551@2|Bacteria,1ZUEQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
MMS3_k127_1884886_7	1379270.AUXF01000004_gene3192	1.703e-181	580.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMS3_k127_1884886_8	1379270.AUXF01000003_gene3619	5.099e-161	527.0	COG0666@1|root,COG0666@2|Bacteria,1ZUQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1895191_19	204669.Acid345_1619	6.619e-113	374.0	COG0577@1|root,COG0577@2|Bacteria,3Y4MY@57723|Acidobacteria,2JMXU@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1895191_20	204669.Acid345_1620	2.347e-107	352.0	COG1136@1|root,COG1136@2|Bacteria,3Y4A6@57723|Acidobacteria,2JMVQ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1895191_15	204669.Acid345_1621	5.059e-124	409.0	COG0845@1|root,COG0845@2|Bacteria,3Y50Z@57723|Acidobacteria,2JMYN@204432|Acidobacteriia	204432|Acidobacteriia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMS3_k127_1895191_25	266117.Rxyl_1776	8.717e-73	256.0	COG1707@1|root,COG1707@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	ACT
MMS3_k127_1895191_0	204669.Acid345_2533	0.0	1110.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1895191_41	316274.Haur_1497	4.165e-21	97.0	COG1476@1|root,COG1476@2|Bacteria,2G9QI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM helix-turn-helix domain protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
MMS3_k127_1895191_50	926569.ANT_03020	1.233e-09	61.0	2BH31@1|root,32B3S@2|Bacteria,2G9T0@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
MMS3_k127_1895191_46	1267535.KB906767_gene4435	4.395e-13	80.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1895191_49	1120971.AUCA01000025_gene762	7.506e-10	65.0	2DNPA@1|root,32YE5@2|Bacteria,1VHDJ@1239|Firmicutes,4HMXA@91061|Bacilli	91061|Bacilli	S	Stress responsive	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
MMS3_k127_1895191_8	861299.J421_2246	7.618e-154	501.0	COG2234@1|root,COG2234@2|Bacteria,1ZU8Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_1895191_22	639030.JHVA01000001_gene2056	1.558e-76	276.0	COG0815@1|root,COG0815@2|Bacteria,3Y4TQ@57723|Acidobacteria,2JKAE@204432|Acidobacteriia	204432|Acidobacteriia	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
MMS3_k127_1895191_33	1297865.APJD01000003_gene6162	1.173e-54	203.0	COG2518@1|root,COG2518@2|Bacteria,1RAIE@1224|Proteobacteria,2U6D7@28211|Alphaproteobacteria,3JUZU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	pcm1	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
MMS3_k127_1895191_47	1009370.ALO_06578	3.552e-12	79.0	COG0727@1|root,COG0727@2|Bacteria,1U20W@1239|Firmicutes,4H3W0@909932|Negativicutes	909932|Negativicutes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
MMS3_k127_1895191_4	1144275.COCOR_02843	6.268e-201	641.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YVB7@29|Myxococcales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_1895191_34	1429916.X566_08450	8.764e-50	182.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,3JYQC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
MMS3_k127_1895191_38	368408.Tpen_0255	2.486e-33	146.0	COG0436@1|root,arCOG01130@2157|Archaea,2XPPF@28889|Crenarchaeota	28889|Crenarchaeota	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_1895191_1	204669.Acid345_2533	0.0	1045.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1895191_14	1185876.BN8_01107	7.93e-143	466.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,47K1G@768503|Cytophagia	976|Bacteroidetes	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_1895191_26	1267535.KB906767_gene4453	5.629e-72	252.0	COG2220@1|root,COG2220@2|Bacteria,3Y739@57723|Acidobacteria	57723|Acidobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
MMS3_k127_1895191_17	439235.Dalk_1881	4.429e-116	403.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_1895191_45	391625.PPSIR1_29905	2.571e-13	84.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria,2YUQA@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
MMS3_k127_1895191_18	240015.ACP_3470	8.635e-116	398.0	COG0473@1|root,COG0473@2|Bacteria,3Y38Z@57723|Acidobacteria,2JHJJ@204432|Acidobacteriia	204432|Acidobacteriia	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS3_k127_1895191_5	292459.STH2116	2.001e-196	628.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
MMS3_k127_1895191_31	1303518.CCALI_02738	1.045e-59	212.0	COG0066@1|root,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
MMS3_k127_1895191_52	1158606.I579_00997	6.753e-07	60.0	COG1670@1|root,COG1670@2|Bacteria,1V2FI@1239|Firmicutes,4HFU6@91061|Bacilli	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
MMS3_k127_1895191_30	1198114.AciX9_2897	1.756e-62	237.0	COG1404@1|root,COG5164@1|root,COG1404@2|Bacteria,COG5164@2|Bacteria,3Y5WB@57723|Acidobacteria,2JK6I@204432|Acidobacteriia	204432|Acidobacteriia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
MMS3_k127_1895191_37	1254432.SCE1572_17975	2.834e-35	139.0	COG0784@1|root,COG0784@2|Bacteria,1N7IK@1224|Proteobacteria,42VBR@68525|delta/epsilon subdivisions,2WRA1@28221|Deltaproteobacteria,2Z0IT@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMS3_k127_1895191_21	1174528.JH992898_gene771	9.136e-79	282.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
MMS3_k127_1895191_51	1500893.JQNB01000001_gene2981	2.772e-09	70.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RWHB@1236|Gammaproteobacteria,1X3VE@135614|Xanthomonadales	135614|Xanthomonadales	EU	Dipeptidyl aminopeptidase acylaminoacyl peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_1895191_24	1303518.CCALI_00715	7.633e-74	263.0	COG1230@1|root,COG1230@2|Bacteria	2|Bacteria	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
MMS3_k127_1895191_43	247634.GPB2148_1942	1.363e-19	94.0	COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria,1JAKJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMS3_k127_1895191_7	234267.Acid_2315	4.879e-160	537.0	COG2120@1|root,COG2120@2|Bacteria,3Y3BV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_1895191_54	666685.R2APBS1_0850	0.0004643	48.0	COG2823@1|root,COG2823@2|Bacteria,1PY9T@1224|Proteobacteria,1T6Y1@1236|Gammaproteobacteria,1X8DX@135614|Xanthomonadales	135614|Xanthomonadales	S	periplasmic or secreted lipoprotein	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
MMS3_k127_1895191_12	1324957.K933_11936	3.937e-144	471.0	COG0624@1|root,arCOG01107@2157|Archaea,2XU86@28890|Euryarchaeota,23ST7@183963|Halobacteria	183963|Halobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_1895191_2	234267.Acid_1818	8.636e-270	848.0	COG3590@1|root,COG3590@2|Bacteria,3Y31X@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase M13	-	-	3.4.24.71	ko:K01415	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
MMS3_k127_1895191_42	234267.Acid_2955	2.619e-20	103.0	2FBCE@1|root,343I9@2|Bacteria,3Y8Q4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1895191_29	234267.Acid_2953	2.531e-63	229.0	COG2304@1|root,COG2304@2|Bacteria,3Y7U1@57723|Acidobacteria	2|Bacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	FHA,VWA,VWA_2
MMS3_k127_1895191_36	370438.PTH_1717	4.942e-37	150.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261SF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
MMS3_k127_1895191_13	118163.Ple7327_4092	1.347e-143	468.0	COG0104@1|root,COG0104@2|Bacteria,1G147@1117|Cyanobacteria,3VHUG@52604|Pleurocapsales	1117|Cyanobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
MMS3_k127_1895191_9	215803.DB30_6881	2.621e-151	494.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria,2YUFR@29|Myxococcales	28221|Deltaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
MMS3_k127_1895191_3	479434.Sthe_1107	3.726e-261	814.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi,27Z10@189775|Thermomicrobia	189775|Thermomicrobia	E	Urocanase C-terminal domain	-	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
MMS3_k127_1895191_48	342949.PNA2_0582	2.651e-10	74.0	COG1672@1|root,arCOG03169@2157|Archaea,2Y162@28890|Euryarchaeota,243JN@183968|Thermococci	183968|Thermococci	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2,HTH_24,Mrr_cat
MMS3_k127_1895191_28	1267533.KB906733_gene3234	5.93e-64	230.0	COG0571@1|root,COG0571@2|Bacteria,3Y4M2@57723|Acidobacteria,2JJ95@204432|Acidobacteriia	204432|Acidobacteriia	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
MMS3_k127_1895191_32	204669.Acid345_1335	2.992e-57	225.0	COG0840@1|root,COG2208@1|root,COG0840@2|Bacteria,COG2208@2|Bacteria,3Y2P9@57723|Acidobacteria,2JIVP@204432|Acidobacteriia	204432|Acidobacteriia	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
MMS3_k127_1895191_10	240015.ACP_1006	2.883e-149	482.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_1895191_23	671143.DAMO_3038	4.951e-75	258.0	COG0586@1|root,COG0586@2|Bacteria,2NQ0I@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	dedA	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
MMS3_k127_1895191_39	446468.Ndas_4630	3.642e-26	111.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria,4EKE7@85012|Streptosporangiales	201174|Actinobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
MMS3_k127_1895191_11	880072.Desac_0610	5.37e-146	475.0	COG0863@1|root,COG0863@2|Bacteria,1R8XS@1224|Proteobacteria	1224|Proteobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
MMS3_k127_1895191_53	1297617.JPJD01000074_gene1638	0.0004181	48.0	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,24T8S@186801|Clostridia,269M7@186813|unclassified Clostridiales	186801|Clostridia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
MMS3_k127_1895191_44	504487.JCM19302_1728	1.226e-13	82.0	COG3746@1|root,COG3746@2|Bacteria,4NIID@976|Bacteroidetes,1I11K@117743|Flavobacteriia	976|Bacteroidetes	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4,Porin_O_P
MMS3_k127_1895191_16	926550.CLDAP_03770	3.914e-116	394.0	COG0176@1|root,COG0176@2|Bacteria,2GA93@200795|Chloroflexi	200795|Chloroflexi	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
MMS3_k127_1895191_27	269799.Gmet_2618	3.69e-67	237.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,43TFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
MMS3_k127_1895191_6	1444711.CCJF01000005_gene1538	9.563e-185	583.0	COG1830@1|root,COG1830@2|Bacteria,2JFHK@204428|Chlamydiae	204428|Chlamydiae	G	Fructose-bisphosphate aldolase class	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
MMS3_k127_1895191_40	234267.Acid_4496	8.071e-25	110.0	COG2318@1|root,COG2318@2|Bacteria,3Y8UQ@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
MMS3_k127_1895191_35	1267533.KB906740_gene318	1.632e-37	155.0	COG0265@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
MMS3_k127_1928693_2	234267.Acid_2446	3.987e-106	356.0	COG0329@1|root,COG0329@2|Bacteria,3Y8R8@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_1928693_0	1267534.KB906760_gene1359	6.256e-315	981.0	COG2366@1|root,COG2366@2|Bacteria,3Y38M@57723|Acidobacteria,2JM6Q@204432|Acidobacteriia	204432|Acidobacteriia	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
MMS3_k127_1928693_8	1211112.ALJC01000050_gene2133	1.222e-12	76.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
MMS3_k127_1928693_7	1121456.ATVA01000016_gene1958	2.523e-41	160.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,43BTI@68525|delta/epsilon subdivisions,2X74F@28221|Deltaproteobacteria,2MCV3@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
MMS3_k127_1928693_6	290397.Adeh_4141	5.021e-43	165.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_1928693_4	404589.Anae109_4288	7.065e-65	252.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DAGAT
MMS3_k127_1928693_3	404589.Anae109_4289	9.401e-68	261.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS3_k127_1928693_1	290397.Adeh_4147	1.61e-107	361.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
MMS3_k127_1949873_8	663278.Ethha_2793	4.872e-18	93.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3WIRQ@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
MMS3_k127_1949873_0	240015.ACP_2349	5.072e-196	629.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
MMS3_k127_1949873_2	1267534.KB906758_gene2239	1.214e-97	336.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria,2JHNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
MMS3_k127_1949873_7	1410617.JHXH01000020_gene1608	1.567e-18	100.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WHR4@541000|Ruminococcaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
MMS3_k127_1949873_4	1047013.AQSP01000133_gene2153	2.695e-95	334.0	COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria	2|Bacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
MMS3_k127_1949873_6	1183438.GKIL_2212	9.157e-24	104.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
MMS3_k127_1949873_10	883156.HMPREF9282_00356	2.16e-11	69.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4H5JA@909932|Negativicutes	909932|Negativicutes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
MMS3_k127_1949873_9	234267.Acid_1093	1.051e-13	72.0	COG0230@1|root,COG0230@2|Bacteria,3Y5W7@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
MMS3_k127_1949873_1	204669.Acid345_0001	1.195e-156	507.0	COG0593@1|root,COG0593@2|Bacteria,3Y2HA@57723|Acidobacteria,2JHN7@204432|Acidobacteriia	204432|Acidobacteriia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
MMS3_k127_1949873_3	234267.Acid_0002	4.001e-96	327.0	COG0592@1|root,COG0592@2|Bacteria,3Y2WE@57723|Acidobacteria	57723|Acidobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
MMS3_k127_1949873_5	56780.SYN_02049	2.545e-78	269.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MQ5F@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMS3_k127_2020345_2	234267.Acid_4267	2.431e-138	461.0	COG0577@1|root,COG0577@2|Bacteria,3Y3U3@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_2020345_8	573370.DMR_04640	4.357e-29	121.0	COG2771@1|root,COG2771@2|Bacteria,1NAK1@1224|Proteobacteria,42VEJ@68525|delta/epsilon subdivisions,2WS0Q@28221|Deltaproteobacteria,2MCWR@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019
MMS3_k127_2020345_0	861299.J421_0704	0.0	1033.0	COG0577@1|root,COG0577@2|Bacteria,1ZUI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_2020345_4	76114.ebA2553	3.31e-90	305.0	2CCV8@1|root,2Z7KX@2|Bacteria,1MY2J@1224|Proteobacteria,2VQKP@28216|Betaproteobacteria,2KY0X@206389|Rhodocyclales	206389|Rhodocyclales	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
MMS3_k127_2020345_5	1538295.JY96_18405	4.914e-84	284.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria,1KN9K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
MMS3_k127_2020345_7	861299.J421_1476	1.079e-65	241.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
MMS3_k127_2020345_3	1267535.KB906767_gene650	1.709e-91	307.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS3_k127_2020345_9	338966.Ppro_3336	1.496e-18	96.0	COG0457@1|root,COG0463@1|root,COG1216@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,COG1216@2|Bacteria,1P77I@1224|Proteobacteria,42TJP@68525|delta/epsilon subdivisions,2WR5S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
MMS3_k127_2020345_6	365044.Pnap_4016	1.453e-73	259.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VKYM@28216|Betaproteobacteria,4AA9N@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_2020345_1	1379270.AUXF01000003_gene3608	2.011e-280	881.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1ZSS1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
MMS3_k127_204846_1	398767.Glov_0077	3.423e-144	462.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,42UUC@68525|delta/epsilon subdivisions,2WQ03@28221|Deltaproteobacteria,43VS7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMS3_k127_204846_4	1458357.BG58_11775	1.602e-95	327.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2VN18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
MMS3_k127_204846_7	1267535.KB906767_gene956	9.038e-56	207.0	COG0596@1|root,COG0596@2|Bacteria,3Y89S@57723|Acidobacteria	57723|Acidobacteria	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_204846_9	1205680.CAKO01000002_gene2206	8.768e-43	175.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMS3_k127_204846_2	443143.GM18_0355	4.521e-105	353.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2WK7T@28221|Deltaproteobacteria,43SX7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_204846_10	1129374.AJE_11219	1.991e-13	78.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,1RPXN@1236|Gammaproteobacteria,467XW@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Transcriptional regulator	acrR	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
MMS3_k127_204846_8	870187.Thini_3802	2.265e-44	169.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cccE	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
MMS3_k127_204846_0	189753.AXAS01000011_gene7627	0.0	1480.0	COG3210@1|root,COG3210@2|Bacteria,1NR4S@1224|Proteobacteria	1224|Proteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_204846_5	1267534.KB906754_gene3648	4.218e-68	239.0	298RU@1|root,2ZVW4@2|Bacteria,3Y4I6@57723|Acidobacteria,2JMQI@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_204846_6	448385.sce1012	2.381e-63	225.0	COG2021@1|root,COG2021@2|Bacteria,1PG00@1224|Proteobacteria,439DK@68525|delta/epsilon subdivisions,2X4NG@28221|Deltaproteobacteria,2YZAN@29|Myxococcales	28221|Deltaproteobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_204846_3	1234364.AMSF01000013_gene633	5.58e-100	335.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1X5B4@135614|Xanthomonadales	135614|Xanthomonadales	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
MMS3_k127_2081097_1	876269.ARWA01000001_gene430	0.0	1092.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,2U2F7@28211|Alphaproteobacteria,3NC95@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
MMS3_k127_2081097_2	1244869.H261_11535	1.613e-115	383.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,2VEMM@28211|Alphaproteobacteria,2JRBP@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMS3_k127_2081097_4	1278073.MYSTI_07101	1.253e-11	77.0	COG1538@1|root,COG1538@2|Bacteria,1R8XP@1224|Proteobacteria,43AHZ@68525|delta/epsilon subdivisions,2X5Y6@28221|Deltaproteobacteria,2Z37Q@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_2081097_0	204669.Acid345_2817	0.0	1199.0	COG0841@1|root,COG0841@2|Bacteria,3Y2TW@57723|Acidobacteria,2JIKU@204432|Acidobacteriia	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
MMS3_k127_2081097_3	204669.Acid345_2818	2.347e-77	271.0	COG0845@1|root,COG0845@2|Bacteria,3Y2NU@57723|Acidobacteria,2JHM0@204432|Acidobacteriia	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMS3_k127_211337_1	1047013.AQSP01000132_gene1707	4.645e-118	393.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	rfbB	-	3.6.3.38,3.6.3.40	ko:K01990,ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
MMS3_k127_211337_3	1125863.JAFN01000001_gene3040	5.595e-52	190.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
MMS3_k127_211337_0	1267535.KB906767_gene1342	2.207e-280	906.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
MMS3_k127_211337_5	240015.ACP_1060	1.664e-10	73.0	COG0760@1|root,COG0760@2|Bacteria,3Y3BW@57723|Acidobacteria,2JIP1@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
MMS3_k127_211337_4	330214.NIDE2714	1.529e-32	133.0	COG0250@1|root,COG0250@2|Bacteria,3J17S@40117|Nitrospirae	40117|Nitrospirae	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
MMS3_k127_211337_2	401526.TcarDRAFT_0919	6.732e-71	254.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4H37S@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
MMS3_k127_2171293_5	530564.Psta_0043	9.689e-17	89.0	COG2881@1|root,COG3170@1|root,COG2881@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	ko:K08086,ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FliO,Yip1
MMS3_k127_2171293_7	58123.JOFJ01000002_gene2459	8.171e-08	64.0	2EGD2@1|root,33A4V@2|Bacteria,2ISJV@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
MMS3_k127_2171293_3	234267.Acid_2449	1.437e-86	295.0	COG2159@1|root,COG2159@2|Bacteria,3Y6P0@57723|Acidobacteria	57723|Acidobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS3_k127_2171293_4	1121930.AQXG01000007_gene502	1.932e-79	276.0	COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1IV1T@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_2171293_2	1267533.KB906738_gene2436	3.264e-105	372.0	COG1629@1|root,COG4771@2|Bacteria,3Y7F9@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
MMS3_k127_2171293_1	448385.sce2299	1.096e-127	425.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YWKI@29|Myxococcales	28221|Deltaproteobacteria	H	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
MMS3_k127_2171293_0	234267.Acid_0103	1.238e-222	712.0	COG0477@1|root,COG2814@2|Bacteria,3Y2YV@57723|Acidobacteria	57723|Acidobacteria	EGP	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
MMS3_k127_2171293_6	1121430.JMLG01000004_gene889	7.363e-14	79.0	COG1309@1|root,COG1309@2|Bacteria,1VFX3@1239|Firmicutes,24GN9@186801|Clostridia,26318@186807|Peptococcaceae	186801|Clostridia	K	YsiA-like protein, C-terminal region	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
MMS3_k127_218125_1	234267.Acid_3778	3.633e-152	510.0	COG0577@1|root,COG0577@2|Bacteria,3Y3Z1@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_218125_0	1267535.KB906767_gene2929	1.71e-222	721.0	COG0577@1|root,COG0577@2|Bacteria,3Y6GK@57723|Acidobacteria,2JKI5@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_218125_2	1121920.AUAU01000004_gene743	2.037e-21	108.0	COG0668@1|root,COG0668@2|Bacteria,3Y2HH@57723|Acidobacteria	57723|Acidobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
MMS3_k127_2184682_60	928724.SacglDRAFT_02721	1.782e-18	88.0	COG3265@1|root,COG3265@2|Bacteria,2GMW2@201174|Actinobacteria,4E4C8@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM Carbohydrate kinase, thermoresistant glucokinase	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_33,SKI
MMS3_k127_2184682_16	1279009.ADICEAN_04165	5.389e-117	402.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,47KUN@768503|Cytophagia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
MMS3_k127_2184682_30	269798.CHU_0074	1.171e-91	312.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,47KGY@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
MMS3_k127_2184682_39	391037.Sare_2247	5.122e-72	256.0	COG0778@1|root,COG0778@2|Bacteria,2GPB4@201174|Actinobacteria,4D8DE@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_2184682_24	1313172.YM304_34270	1.133e-100	331.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4CMXQ@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
MMS3_k127_2184682_31	204669.Acid345_1481	6.359e-91	320.0	COG0460@1|root,COG3830@1|root,COG0460@2|Bacteria,COG3830@2|Bacteria,3Y2VY@57723|Acidobacteria,2JHYQ@204432|Acidobacteriia	204432|Acidobacteriia	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
MMS3_k127_2184682_67	1047013.AQSP01000095_gene2301	8.75e-12	76.0	2DS9E@1|root,32VU1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2184682_13	1242864.D187_004264	1.915e-151	487.0	COG0451@1|root,COG0451@2|Bacteria,1MU1A@1224|Proteobacteria,42RJF@68525|delta/epsilon subdivisions,2WNGK@28221|Deltaproteobacteria,2Z0BU@29|Myxococcales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_2184682_36	1191523.MROS_1190	1.601e-82	284.0	COG0101@1|root,COG0101@2|Bacteria	2|Bacteria	J	tRNA pseudouridine synthase activity	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
MMS3_k127_2184682_29	379066.GAU_2049	2.255e-93	317.0	COG0730@1|root,COG0730@2|Bacteria,1ZUET@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	response to heat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2184682_32	211114.JOEF01000008_gene1255	1.246e-90	310.0	COG0715@1|root,COG0715@2|Bacteria,2GNMC@201174|Actinobacteria,4E006@85010|Pseudonocardiales	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
MMS3_k127_2184682_27	1380394.JADL01000001_gene3109	4.645e-97	329.0	COG0600@1|root,COG0600@2|Bacteria,1MVD2@1224|Proteobacteria,2TT6U@28211|Alphaproteobacteria,2JZKX@204441|Rhodospirillales	204441|Rhodospirillales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
MMS3_k127_2184682_28	1123023.JIAI01000008_gene1273	4.41e-96	329.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4E0KN@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
MMS3_k127_2184682_65	1040987.AZUY01000025_gene5464	1.347e-13	81.0	COG1853@1|root,COG2267@1|root,COG1853@2|Bacteria,COG2267@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,43KYI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	flavin reductase	ntaB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Flavin_Reduct
MMS3_k127_2184682_57	1385518.N798_08275	1.492e-26	114.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria,4FHD4@85021|Intrasporangiaceae	201174|Actinobacteria	O	Osmotically inducible protein OsmC	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,OsmC
MMS3_k127_2184682_22	204669.Acid345_3014	2.578e-105	365.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
MMS3_k127_2184682_68	478741.JAFS01000001_gene2098	1.369e-07	60.0	2C6YV@1|root,3392Q@2|Bacteria,46T7D@74201|Verrucomicrobia,37GSH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2184682_14	682795.AciX8_3665	3.172e-145	469.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS3_k127_2184682_12	909663.KI867150_gene1775	2.264e-168	546.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2MQN5@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PLD-like domain	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
MMS3_k127_2184682_69	1323663.AROI01000018_gene615	4.393e-06	57.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	fleR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_2184682_41	266117.Rxyl_1661	1.36e-64	227.0	COG1247@1|root,COG1247@2|Bacteria,2H1MI@201174|Actinobacteria,4CQH6@84995|Rubrobacteria	84995|Rubrobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
MMS3_k127_2184682_17	1254432.SCE1572_44215	4.78e-112	366.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,42MXW@68525|delta/epsilon subdivisions,2WK94@28221|Deltaproteobacteria,2YWE8@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
MMS3_k127_2184682_10	1254432.SCE1572_44220	3.545e-180	578.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,42PXZ@68525|delta/epsilon subdivisions,2X667@28221|Deltaproteobacteria,2Z33M@29|Myxococcales	28221|Deltaproteobacteria	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
MMS3_k127_2184682_53	1304872.JAGC01000003_gene3670	2.607e-34	153.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2M9S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
MMS3_k127_2184682_66	1121430.JMLG01000012_gene1977	3.316e-12	74.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
MMS3_k127_2184682_44	1205680.CAKO01000006_gene3426	3.926e-54	201.0	COG2518@1|root,COG2518@2|Bacteria,1MXJM@1224|Proteobacteria,2TW3B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
MMS3_k127_2184682_19	1267535.KB906767_gene5350	1.594e-108	367.0	COG1538@1|root,COG1538@2|Bacteria,3Y3PX@57723|Acidobacteria,2JHUZ@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_2184682_21	1267535.KB906767_gene5351	1.717e-105	359.0	COG0845@1|root,COG0845@2|Bacteria,3Y3C9@57723|Acidobacteria,2JIN9@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
MMS3_k127_2184682_0	1267535.KB906767_gene5352	0.0	1175.0	COG0841@1|root,COG0841@2|Bacteria,3Y3F4@57723|Acidobacteria,2JIHS@204432|Acidobacteriia	204432|Acidobacteriia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMS3_k127_2184682_43	555500.I215_06012	4.187e-59	213.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
MMS3_k127_2184682_47	204669.Acid345_4036	9.743e-45	173.0	COG0561@1|root,COG0561@2|Bacteria,3Y4J5@57723|Acidobacteria,2JJB7@204432|Acidobacteriia	204432|Acidobacteriia	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
MMS3_k127_2184682_52	331678.Cphamn1_0650	4.592e-38	154.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_2184682_71	67275.JOAP01000019_gene1212	0.0004924	53.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
MMS3_k127_2184682_26	1131269.AQVV01000001_gene1364	6.143e-98	340.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
MMS3_k127_2184682_7	518766.Rmar_0629	1.561e-234	764.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
MMS3_k127_2184682_64	1541065.JRFE01000057_gene6269	4.728e-14	78.0	2DUIA@1|root,32UXB@2|Bacteria	2|Bacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
MMS3_k127_2184682_6	1340493.JNIF01000004_gene652	4.218e-238	752.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
MMS3_k127_2184682_40	1232410.KI421426_gene1377	3.231e-68	237.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,42MQB@68525|delta/epsilon subdivisions,2WPIA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
MMS3_k127_2184682_5	234267.Acid_1951	1.802e-263	844.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
MMS3_k127_2184682_2	861299.J421_1116	0.0	1035.0	COG4447@1|root,COG4447@2|Bacteria,1ZUES@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_2184682_49	1356852.N008_16100	5.145e-42	166.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,47PDK@768503|Cytophagia	976|Bacteroidetes	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
MMS3_k127_2184682_37	1128427.KB904821_gene174	7.748e-82	281.0	COG0705@1|root,COG0705@2|Bacteria,1G5IY@1117|Cyanobacteria,1HF1W@1150|Oscillatoriales	1117|Cyanobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMS3_k127_2184682_4	1382359.JIAL01000001_gene577	3.709e-271	847.0	COG1217@1|root,COG1217@2|Bacteria,3Y33Q@57723|Acidobacteria,2JIIC@204432|Acidobacteriia	204432|Acidobacteriia	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_2184682_18	401526.TcarDRAFT_2158	6.877e-111	380.0	COG1063@1|root,COG1063@2|Bacteria,1U5GN@1239|Firmicutes	1239|Firmicutes	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_2184682_62	330214.NIDE1855	8.583e-17	81.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_2184682_9	1379698.RBG1_1C00001G0509	2.656e-203	656.0	COG1042@1|root,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria	2|Bacteria	C	synthetase (ADP forming), alpha	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
MMS3_k127_2184682_3	1125863.JAFN01000001_gene1462	5.048e-300	944.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
MMS3_k127_2184682_50	1267535.KB906767_gene1076	2.725e-41	155.0	COG1937@1|root,COG1937@2|Bacteria	2|Bacteria	S	negative regulation of transcription, DNA-templated	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
MMS3_k127_2184682_20	404589.Anae109_2766	1.413e-106	357.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
MMS3_k127_2184682_70	797209.ZOD2009_14016	1.262e-05	49.0	arCOG03909@1|root,arCOG03909@2157|Archaea,2Y7II@28890|Euryarchaeota,241I0@183963|Halobacteria	183963|Halobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
MMS3_k127_2184682_48	886293.Sinac_4160	8.238e-43	163.0	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_2184682_56	1230457.C476_03743	2.777e-28	126.0	COG0589@1|root,arCOG00449@2157|Archaea,2XVPB@28890|Euryarchaeota,23SHQ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2184682_59	266117.Rxyl_1013	1.691e-18	91.0	COG0517@1|root,COG4747@1|root,COG0517@2|Bacteria,COG4747@2|Bacteria,2GSAR@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
MMS3_k127_2184682_51	196367.JNFG01000015_gene3939	2.68e-38	158.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,1K383@119060|Burkholderiaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMS3_k127_2184682_58	1379270.AUXF01000007_gene1062	1.619e-22	104.0	COG1950@1|root,COG1950@2|Bacteria	2|Bacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
MMS3_k127_2184682_15	330214.NIDE4257	2.19e-129	419.0	COG2084@1|root,COG2084@2|Bacteria,3J0R5@40117|Nitrospirae	40117|Nitrospirae	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_2184682_55	706587.Desti_2517	1.34e-31	136.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WMWV@28221|Deltaproteobacteria,2MRAE@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	fnr-1	-	-	ko:K01420,ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_2184682_8	246197.MXAN_6050	3.303e-223	706.0	COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,437VH@68525|delta/epsilon subdivisions,2X354@28221|Deltaproteobacteria,2YUAY@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
MMS3_k127_2184682_54	502025.Hoch_0331	8.142e-34	143.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,42SD7@68525|delta/epsilon subdivisions,2WPI5@28221|Deltaproteobacteria,2YVK5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
MMS3_k127_2184682_33	1128421.JAGA01000001_gene2365	1.456e-90	310.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
MMS3_k127_2184682_1	240015.ACP_2022	0.0	1156.0	COG1048@1|root,COG1048@2|Bacteria,3Y34Q@57723|Acidobacteria,2JHMV@204432|Acidobacteriia	204432|Acidobacteriia	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMS3_k127_2184682_34	243231.GSU2261	9.751e-88	305.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,43SZS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
MMS3_k127_2184682_38	1183438.GKIL_3768	6.832e-79	292.0	COG0612@1|root,COG0612@2|Bacteria,1G303@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_2184682_23	1183438.GKIL_3767	2.9e-104	355.0	COG0612@1|root,COG0612@2|Bacteria,1G1CD@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the peptidase M16 family	pqqE	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_2184682_25	1125863.JAFN01000001_gene3410	2.004e-99	336.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
MMS3_k127_2184682_61	158500.BV97_01028	7.766e-18	96.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,2U5TK@28211|Alphaproteobacteria,2K3A3@204457|Sphingomonadales	204457|Sphingomonadales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
MMS3_k127_2184682_35	671143.DAMO_2526	6.448e-85	292.0	COG0648@1|root,COG0648@2|Bacteria,2NNN3@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
MMS3_k127_2184682_46	573370.DMR_28890	2.613e-45	171.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2WP66@28221|Deltaproteobacteria,2MB3T@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
MMS3_k127_2184682_42	56780.SYN_00074	1.953e-59	218.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
MMS3_k127_2184682_63	635013.TherJR_0870	8.873e-15	79.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,262GD@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
MMS3_k127_2184682_11	671143.DAMO_0810	1.237e-171	553.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_2209410_13	903818.KI912268_gene3354	3.648e-78	273.0	COG1868@1|root,COG1868@2|Bacteria,3Y49R@57723|Acidobacteria	57723|Acidobacteria	N	flagellar motor switch protein FliM	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
MMS3_k127_2209410_18	1123371.ATXH01000004_gene1761	9.732e-47	188.0	COG1191@1|root,COG1191@2|Bacteria,2GHGC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Sigma-70, region 4	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_2209410_15	903818.KI912268_gene3352	2.217e-64	230.0	COG0455@1|root,COG0455@2|Bacteria	2|Bacteria	D	bacterial-type flagellum organization	flhG	-	-	ko:K02282,ko:K04562	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
MMS3_k127_2209410_19	886293.Sinac_7410	5.498e-44	175.0	COG1419@1|root,COG1419@2|Bacteria,2IYTZ@203682|Planctomycetes	203682|Planctomycetes	N	GTP-binding signal recognition particle SRP54	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
MMS3_k127_2209410_1	1125863.JAFN01000001_gene688	1.687e-195	630.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2WIWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
MMS3_k127_2209410_16	1430331.EP10_17050	7.092e-64	233.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,4HB7Y@91061|Bacilli,1WFIC@129337|Geobacillus	91061|Bacilli	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
MMS3_k127_2209410_24	335283.Neut_2061	5.622e-33	137.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2VQ64@28216|Betaproteobacteria,37217@32003|Nitrosomonadales	28216|Betaproteobacteria	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
MMS3_k127_2209410_30	177437.HRM2_37150	1.25e-11	68.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,42VAB@68525|delta/epsilon subdivisions,2WR6X@28221|Deltaproteobacteria,2MKJM@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420,ko:K03227	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	Bac_export_3
MMS3_k127_2209410_14	1267535.KB906767_gene3920	5.773e-72	257.0	COG1338@1|root,COG1338@2|Bacteria,3Y3K4@57723|Acidobacteria,2JIGN@204432|Acidobacteriia	204432|Acidobacteriia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
MMS3_k127_2209410_33	743721.Psesu_1488	2.232e-07	60.0	COG3190@1|root,COG3190@2|Bacteria,1N79Z@1224|Proteobacteria,1SCKP@1236|Gammaproteobacteria,1X7RQ@135614|Xanthomonadales	135614|Xanthomonadales	N	flagellar	fliO	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
MMS3_k127_2209410_37	686340.Metal_1737	7.977e-05	49.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,1XFB5@135618|Methylococcales	135618|Methylococcales	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
MMS3_k127_2209410_28	1267534.KB906755_gene4218	1.896e-13	78.0	COG1580@1|root,COG1580@2|Bacteria,3Y8M7@57723|Acidobacteria,2JNFJ@204432|Acidobacteriia	204432|Acidobacteriia	N	Flagellar basal body-associated protein FliL	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
MMS3_k127_2209410_38	1142394.PSMK_21680	0.0001038	55.0	COG3144@1|root,COG3144@2|Bacteria,2J0UT@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar hook-length control protein	-	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
MMS3_k127_2209410_11	240015.ACP_0244	4.333e-80	282.0	COG1749@1|root,COG1749@2|Bacteria,3Y3C0@57723|Acidobacteria,2JHZM@204432|Acidobacteriia	204432|Acidobacteriia	N	Flagellar basal body protein FlaE	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
MMS3_k127_2209410_32	1206777.B195_06995	1.04e-10	72.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,1Z5AW@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
MMS3_k127_2209410_36	1121468.AUBR01000057_gene1479	9.18e-06	54.0	2DD11@1|root,2ZG39@2|Bacteria	2|Bacteria	S	Flagellar FliJ protein	-	-	-	-	-	-	-	-	-	-	-	-	FliJ
MMS3_k127_2209410_6	635013.TherJR_1539	4.597e-148	482.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,26126@186807|Peptococcaceae	186801|Clostridia	NU	TIGRFAM ATPase, FliI YscN family	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
MMS3_k127_2209410_29	1283300.ATXB01000001_gene960	1.228e-11	74.0	COG1317@1|root,COG1317@2|Bacteria,1NMQE@1224|Proteobacteria,1RR8H@1236|Gammaproteobacteria,1XEKY@135618|Methylococcales	135618|Methylococcales	N	PFAM Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
MMS3_k127_2209410_8	903818.KI912268_gene1678	4.23e-116	384.0	COG1536@1|root,COG1536@2|Bacteria,3Y2U7@57723|Acidobacteria	57723|Acidobacteria	N	flagellar motor switch protein FliG	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
MMS3_k127_2209410_12	1249634.D781_2720	2.251e-78	282.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,402QI@613|Serratia	1236|Gammaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
MMS3_k127_2209410_35	439235.Dalk_0666	5.911e-07	59.0	COG1677@1|root,COG1677@2|Bacteria,1NIFD@1224|Proteobacteria,42V59@68525|delta/epsilon subdivisions,2WSXK@28221|Deltaproteobacteria,2MM8C@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
MMS3_k127_2209410_23	269799.Gmet_3114	3.75e-34	136.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,42TPI@68525|delta/epsilon subdivisions,2WP1C@28221|Deltaproteobacteria,43UY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Flagellar basal body rod FlgEFG protein C-terminal	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
MMS3_k127_2209410_31	748247.AZKH_1306	3.729e-11	71.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,2VUJ4@28216|Betaproteobacteria,2KWX8@206389|Rhodocyclales	206389|Rhodocyclales	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
MMS3_k127_2209410_25	330214.NIDE0779	6.209e-26	115.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_2209410_7	667014.Thein_1806	4.6e-123	416.0	COG2204@1|root,COG2204@2|Bacteria,2GHIR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_2209410_20	204669.Acid345_1776	1.43e-37	153.0	COG2203@1|root,COG3829@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,RsbRD_N
MMS3_k127_2209410_21	1125863.JAFN01000001_gene686	1.679e-36	144.0	COG2199@1|root,COG3706@2|Bacteria,1N0N3@1224|Proteobacteria,43E7J@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Chemotaxis protein cheY	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
MMS3_k127_2209410_27	933262.AXAM01000005_gene2531	1.206e-13	78.0	COG1406@1|root,COG1406@2|Bacteria	2|Bacteria	N	Chemotaxis phosphatase CheX	cheX-3	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
MMS3_k127_2209410_22	667014.Thein_0520	5.253e-36	148.0	COG1639@1|root,COG1639@2|Bacteria,2GGWZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
MMS3_k127_2209410_5	1183438.GKIL_2517	2.152e-154	498.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMS3_k127_2209410_9	1267535.KB906767_gene632	3.404e-115	375.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2209410_3	251221.35211765	1.924e-180	599.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_2209410_2	251221.35211765	6.176e-189	617.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_2209410_10	234267.Acid_6478	6.61e-105	347.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_2209410_0	234267.Acid_4168	6.968e-214	677.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_2209410_4	234267.Acid_4169	2.702e-162	524.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
MMS3_k127_2209410_34	1089547.KB913013_gene761	2.358e-07	59.0	COG4319@1|root,COG4319@2|Bacteria,4NSA0@976|Bacteroidetes,47RMW@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
MMS3_k127_2209410_17	3067.XP_002950971.1	5.506e-56	202.0	COG3145@1|root,KOG2731@2759|Eukaryota,37IW5@33090|Viridiplantae,34NPV@3041|Chlorophyta	3041|Chlorophyta	A	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
MMS3_k127_2209410_26	28229.ND2E_2026	2.792e-23	109.0	COG1073@1|root,COG1073@2|Bacteria,1RBP3@1224|Proteobacteria,1S216@1236|Gammaproteobacteria,2Q5Y1@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
MMS3_k127_221140_10	401053.AciPR4_0642	0.0002009	46.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
MMS3_k127_221140_3	882086.SacxiDRAFT_3705	3.108e-106	361.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4DZ3J@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
MMS3_k127_221140_9	869210.Marky_1547	6.102e-44	169.0	COG4122@1|root,COG4122@2|Bacteria,1WKHV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
MMS3_k127_221140_5	479434.Sthe_2520	6.93e-100	342.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi,27Y0A@189775|Thermomicrobia	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_221140_6	926566.Terro_1965	2.628e-93	317.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria,2JIEY@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_221140_4	639030.JHVA01000001_gene3365	2.328e-100	334.0	COG2171@1|root,COG2171@2|Bacteria,3Y2Z3@57723|Acidobacteria,2JIDV@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_N_2
MMS3_k127_221140_1	234267.Acid_6980	2.437e-120	392.0	COG0329@1|root,COG0329@2|Bacteria,3Y3V8@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_221140_8	234267.Acid_6981	2.921e-61	218.0	COG0289@1|root,COG0289@2|Bacteria,3Y50R@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
MMS3_k127_221140_2	401053.AciPR4_0859	2.402e-116	394.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria,2JHV2@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
MMS3_k127_221140_0	234267.Acid_6983	6.516e-127	416.0	COG0136@1|root,COG0136@2|Bacteria,3Y346@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMS3_k127_221140_7	234267.Acid_1024	1.669e-92	315.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,DUF2048,Hydrolase_4,Peptidase_S9
MMS3_k127_2216191_3	247490.KSU1_D0121	3.102e-184	585.0	COG0538@1|root,COG0538@2|Bacteria,2J51C@203682|Planctomycetes	203682|Planctomycetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
MMS3_k127_2216191_13	1232410.KI421421_gene3580	5.026e-77	271.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43TY0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
MMS3_k127_2216191_0	1267535.KB906767_gene621	9.842e-237	744.0	COG0504@1|root,COG0504@2|Bacteria,3Y2MH@57723|Acidobacteria,2JID4@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
MMS3_k127_2216191_10	999423.HMPREF9161_00820	2.104e-95	321.0	COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,4H20D@909932|Negativicutes	909932|Negativicutes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
MMS3_k127_2216191_5	240015.ACP_1676	3.48e-107	356.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,3Y4I2@57723|Acidobacteria,2JIKP@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
MMS3_k127_2216191_20	1069080.KB913028_gene60	6.187e-44	168.0	COG1778@1|root,COG1778@2|Bacteria,1V5JJ@1239|Firmicutes,4H4ID@909932|Negativicutes	909932|Negativicutes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
MMS3_k127_2216191_17	644282.Deba_1300	1.588e-54	207.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,42UW4@68525|delta/epsilon subdivisions,2WR5T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	-	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2,TPR_7,TPR_8
MMS3_k127_2216191_21	96561.Dole_2184	2.398e-37	154.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2MK2V@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
MMS3_k127_2216191_11	204669.Acid345_4424	1.657e-94	319.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JIT2@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMS3_k127_2216191_12	1123371.ATXH01000001_gene1263	7.122e-86	297.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,2GH0E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
MMS3_k127_2216191_1	1121438.JNJA01000018_gene3318	7.118e-200	636.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42Q9Q@68525|delta/epsilon subdivisions,2WKCR@28221|Deltaproteobacteria,2MGIR@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,PTS_EIIA_2
MMS3_k127_2216191_23	573370.DMR_30760	2.224e-30	131.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WURY@28221|Deltaproteobacteria,2MG3H@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
MMS3_k127_2216191_2	1121920.AUAU01000018_gene1781	2.285e-192	611.0	COG0439@1|root,COG0439@2|Bacteria,3Y2QZ@57723|Acidobacteria	57723|Acidobacteria	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
MMS3_k127_2216191_22	1382359.JIAL01000001_gene1628	9.703e-37	145.0	COG0511@1|root,COG0511@2|Bacteria,3Y4W8@57723|Acidobacteria,2JJHQ@204432|Acidobacteriia	204432|Acidobacteriia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
MMS3_k127_2216191_14	379066.GAU_1926	1.652e-74	264.0	COG0006@1|root,COG0006@2|Bacteria,1ZSTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_2216191_26	1162668.LFE_0959	4.182e-13	77.0	COG0457@1|root,COG0457@2|Bacteria	1162668.LFE_0959|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2216191_25	416348.Hlac_2824	1.059e-21	103.0	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
MMS3_k127_2216191_6	1047013.AQSP01000124_gene2676	7.149e-105	365.0	COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria	2|Bacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
MMS3_k127_2216191_24	1047013.AQSP01000124_gene2678	7.033e-22	103.0	COG3167@1|root,COG3167@2|Bacteria,2NPUF@2323|unclassified Bacteria	2|Bacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
MMS3_k127_2216191_27	1047013.AQSP01000124_gene2679	8.623e-13	76.0	COG3166@1|root,COG3166@2|Bacteria,2NRP1@2323|unclassified Bacteria	2|Bacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
MMS3_k127_2216191_9	1125863.JAFN01000001_gene2287	1.317e-98	334.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
MMS3_k127_2216191_19	1267535.KB906767_gene4507	9.874e-48	180.0	COG0102@1|root,COG0102@2|Bacteria,3Y4U5@57723|Acidobacteria,2JJGG@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
MMS3_k127_2216191_18	234267.Acid_0907	1.286e-48	177.0	COG0103@1|root,COG0103@2|Bacteria,3Y4IK@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
MMS3_k127_2216191_8	204669.Acid345_0563	7.171e-101	337.0	COG0052@1|root,COG0052@2|Bacteria,3Y3K2@57723|Acidobacteria,2JI0A@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
MMS3_k127_2216191_15	935948.KE386494_gene260	5.02e-72	248.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
MMS3_k127_2216191_7	338963.Pcar_1919	3.687e-101	334.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
MMS3_k127_2216191_16	1267535.KB906767_gene4502	3.7e-56	202.0	COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria,2JJ0X@204432|Acidobacteriia	204432|Acidobacteriia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
MMS3_k127_2216191_4	1128421.JAGA01000003_gene2811	9.144e-136	444.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_2225307_1	1267533.KB906738_gene2247	4.945e-89	305.0	COG3975@1|root,COG3975@2|Bacteria,3Y411@57723|Acidobacteria,2JI4Z@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
MMS3_k127_2225307_0	1163617.SCD_n02100	0.0	1168.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
MMS3_k127_2225307_2	1297865.APJD01000014_gene491	9.218e-57	210.0	COG0583@1|root,COG0583@2|Bacteria,1R7M1@1224|Proteobacteria,2VF1J@28211|Alphaproteobacteria,3K2IV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_2245791_8	338963.Pcar_2062	5.235e-26	112.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,42TTQ@68525|delta/epsilon subdivisions,2WR6D@28221|Deltaproteobacteria,43V3X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
MMS3_k127_2245791_11	1227266.HMPREF1551_02103	4.197e-12	76.0	COG1999@1|root,COG1999@2|Bacteria,4NGHC@976|Bacteroidetes,1HXW6@117743|Flavobacteriia,1EQYJ@1016|Capnocytophaga	976|Bacteroidetes	S	SCO1 SenC	ypmQ	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
MMS3_k127_2245791_6	56780.SYN_01247	1.075e-26	113.0	2DCXT@1|root,2ZFR8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2245791_1	251229.Chro_4925	1.039e-53	201.0	COG0664@1|root,COG0664@2|Bacteria,1G1UQ@1117|Cyanobacteria,3VJMP@52604|Pleurocapsales	1117|Cyanobacteria	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
MMS3_k127_2245791_9	204669.Acid345_2174	5.213e-24	107.0	COG1359@1|root,COG1359@2|Bacteria,3Y90H@57723|Acidobacteria,2JNW4@204432|Acidobacteriia	204432|Acidobacteriia	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
MMS3_k127_2245791_7	660470.Theba_0613	1.599e-26	124.0	COG0477@1|root,COG2814@2|Bacteria,2GC08@200918|Thermotogae	200918|Thermotogae	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
MMS3_k127_2245791_0	215803.DB30_4900	5.754e-95	334.0	COG1680@1|root,COG1680@2|Bacteria,1PEI7@1224|Proteobacteria,43DSW@68525|delta/epsilon subdivisions,2X8V3@28221|Deltaproteobacteria,2Z0DE@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_2245791_2	1476583.DEIPH_ctg050orf0040	1.782e-38	151.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC,TusA
MMS3_k127_2245791_5	1047013.AQSP01000143_gene2009	4.636e-30	137.0	COG0457@1|root,COG0457@2|Bacteria	1047013.AQSP01000143_gene2009|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2245791_4	401053.AciPR4_4218	1.49e-34	137.0	COG0577@1|root,COG0577@2|Bacteria,3Y3U3@57723|Acidobacteria,2JMJ0@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_2250237_2	861299.J421_5712	1.605e-99	353.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_5712|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2250237_1	1267534.KB906761_gene1200	3.572e-139	475.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_2250237_0	251221.35211765	1.253e-157	524.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_2251760_0	518766.Rmar_0629	1.094e-185	618.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
MMS3_k127_2251760_2	875328.JDM601_0603	3.861e-29	131.0	2EPHJ@1|root,33H46@2|Bacteria,2GPJD@201174|Actinobacteria,23DXN@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2251760_1	240015.ACP_0487	4.383e-84	287.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2298707_9	378806.STAUR_7741	5.388e-43	178.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,43DYN@68525|delta/epsilon subdivisions,2X924@28221|Deltaproteobacteria,2Z1I3@29|Myxococcales	28221|Deltaproteobacteria	M	Kelch	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
MMS3_k127_2298707_13	1303692.SFUL_229	0.00074	52.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,Ricin_B_lectin,ThuA
MMS3_k127_2298707_11	215803.DB30_4770	6.904e-37	159.0	COG3055@1|root,COG4257@1|root,COG3055@2|Bacteria,COG4257@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
MMS3_k127_2298707_3	234267.Acid_1499	3.696e-87	295.0	COG0330@1|root,COG0330@2|Bacteria,3Y33E@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMS3_k127_2298707_2	234267.Acid_1498	4.11e-95	328.0	COG1030@1|root,COG1030@2|Bacteria,3Y31N@57723|Acidobacteria	57723|Acidobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
MMS3_k127_2298707_7	1382359.JIAL01000001_gene658	2.201e-58	215.0	COG1733@1|root,COG1733@2|Bacteria,3Y7XV@57723|Acidobacteria,2JN1Y@204432|Acidobacteriia	204432|Acidobacteriia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
MMS3_k127_2298707_0	1267535.KB906767_gene3396	2.087e-214	668.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
MMS3_k127_2298707_12	2002.JOEQ01000031_gene1648	9.22e-32	146.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4EPKG@85012|Streptosporangiales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
MMS3_k127_2298707_5	1408419.JHYG01000008_gene2222	2.12e-76	276.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,2JQ4J@204441|Rhodospirillales	204441|Rhodospirillales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_2298707_1	682795.AciX8_4071	7.308e-138	451.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	glxA	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
MMS3_k127_2298707_10	682795.AciX8_4072	1.24e-37	145.0	COG1359@1|root,COG1359@2|Bacteria,3Y5IV@57723|Acidobacteria	57723|Acidobacteria	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2298707_4	204669.Acid345_4452	4.541e-85	297.0	COG0346@1|root,COG0346@2|Bacteria,3Y6UC@57723|Acidobacteria	57723|Acidobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2298707_6	1118054.CAGW01000081_gene2691	2.905e-61	222.0	COG1679@1|root,COG1786@1|root,COG1679@2|Bacteria,COG1786@2|Bacteria,1UJDG@1239|Firmicutes,4HTS5@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
MMS3_k127_23801_3	401526.TcarDRAFT_1924	5.543e-63	222.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4H22J@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
MMS3_k127_23801_2	215803.DB30_5991	3.74e-112	383.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,42ZIG@68525|delta/epsilon subdivisions,2WUZE@28221|Deltaproteobacteria,2YX8Y@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
MMS3_k127_23801_4	1047013.AQSP01000039_gene1083	3.646e-20	93.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_23801_1	234267.Acid_1043	3.353e-116	381.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_23801_0	555079.Toce_0176	1.297e-156	505.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,42EYY@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
MMS3_k127_2461840_4	1167006.UWK_02466	6.412e-29	130.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMS3_k127_2461840_0	861299.J421_6044	6.551e-261	816.0	COG2192@1|root,COG2192@2|Bacteria,1ZUTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
MMS3_k127_2461840_6	644282.Deba_2425	2.225e-13	72.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,42X36@68525|delta/epsilon subdivisions,2WSNU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2461840_8	316278.SynRCC307_0150	9.913e-09	61.0	2DP8V@1|root,33122@2|Bacteria,1G83J@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2461840_9	439493.PB7211_294	0.0002068	51.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,2TXEY@28211|Alphaproteobacteria,4BTEZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Big_3_5
MMS3_k127_2461840_7	1198114.AciX9_2169	1.245e-09	70.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
MMS3_k127_2461840_5	1484460.JSWG01000006_gene2731	3.315e-15	88.0	COG1470@1|root,COG2931@1|root,COG3266@1|root,COG3420@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria,COG3266@2|Bacteria,COG3420@2|Bacteria,4NQBS@976|Bacteroidetes	976|Bacteroidetes	Q	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
MMS3_k127_2461840_2	1267535.KB906767_gene4435	3.183e-70	249.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2461840_1	1382356.JQMP01000001_gene1247	2.437e-110	376.0	COG0028@1|root,COG0028@2|Bacteria,2GBE1@200795|Chloroflexi,27Z26@189775|Thermomicrobia	189775|Thermomicrobia	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_2461840_3	426355.Mrad2831_5097	5.936e-52	199.0	COG0500@1|root,COG2226@2|Bacteria,1R51W@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2501936_3	1313172.YM304_07610	2.105e-99	358.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_2501936_0	41431.PCC8801_3794	2.39e-131	438.0	2EZGF@1|root,33SMM@2|Bacteria,1GKV9@1117|Cyanobacteria,3KG2G@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2501936_9	1116375.VEJY3_18836	1.755e-18	99.0	2C1AX@1|root,33GUX@2|Bacteria,1MZSH@1224|Proteobacteria,1SS1H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2501936_5	1172188.KB911820_gene2425	5.955e-45	186.0	COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4FH84@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2501936_11	1297742.A176_02248	6.151e-07	61.0	COG3291@1|root,COG3291@2|Bacteria,1RCBA@1224|Proteobacteria	1224|Proteobacteria	DZ	Mycoplasma protein of unknown function, DUF285	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF285
MMS3_k127_2501936_2	1379698.RBG1_1C00001G0608	3.386e-112	400.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
MMS3_k127_2501936_4	234267.Acid_2953	3.826e-65	238.0	COG2304@1|root,COG2304@2|Bacteria,3Y7U1@57723|Acidobacteria	2|Bacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	FHA,VWA,VWA_2
MMS3_k127_2501936_8	234267.Acid_2955	2.644e-19	95.0	2FBCE@1|root,343I9@2|Bacteria,3Y8Q4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2501936_10	525909.Afer_0046	1.648e-12	76.0	28SZC@1|root,2ZF8S@2|Bacteria,2HBRK@201174|Actinobacteria,4CNUV@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2501936_12	521098.Aaci_2443	0.000774	51.0	COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli	91061|Bacilli	I	Squalene--hopene cyclase	shc	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
MMS3_k127_2501936_1	713586.KB900536_gene2798	1.469e-115	387.0	COG0515@1|root,COG1361@1|root,COG3391@1|root,COG0515@2|Bacteria,COG1361@2|Bacteria,COG3391@2|Bacteria,1RK5V@1224|Proteobacteria,1SQGH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2501936_7	1206101.AZXC01000003_gene304	1.513e-27	122.0	COG4274@1|root,COG4274@2|Bacteria,2IJ0R@201174|Actinobacteria	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_2544761_8	1382356.JQMP01000003_gene2177	2.39e-39	153.0	COG0764@1|root,COG0764@2|Bacteria,2G8P4@200795|Chloroflexi,27YA6@189775|Thermomicrobia	189775|Thermomicrobia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
MMS3_k127_2544761_2	887898.HMPREF0551_0208	1.216e-174	584.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VI60@28216|Betaproteobacteria,1K0ZI@119060|Burkholderiaceae	28216|Betaproteobacteria	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_2544761_0	1379270.AUXF01000005_gene474	4.728e-207	666.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSZA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_2544761_4	639030.JHVA01000001_gene528	3.263e-117	409.0	COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
MMS3_k127_2544761_1	264732.Moth_1297	9.04e-184	586.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42FNV@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
MMS3_k127_2544761_10	1297865.APJD01000005_gene3814	9.923e-17	90.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,3JQQI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	MA20_15480	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_2544761_9	1173264.KI913949_gene4297	5.806e-38	151.0	COG1695@1|root,COG1695@2|Bacteria,1GDRG@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_2544761_5	933262.AXAM01000098_gene3457	2.063e-94	348.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MNJX@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
MMS3_k127_2544761_6	671143.DAMO_1616	1.368e-93	331.0	COG1034@1|root,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
MMS3_k127_2544761_7	1047013.AQSP01000083_gene1193	9.762e-72	273.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,PD40,Peptidase_M1
MMS3_k127_2544761_3	177437.HRM2_09040	1.562e-137	443.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2MJM9@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_2591341_8	134676.ACPL_6859	0.0006895	50.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4DD5C@85008|Micromonosporales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2591341_7	744980.TRICHSKD4_0588	8.488e-27	123.0	COG0500@1|root,COG2226@2|Bacteria,1QWJE@1224|Proteobacteria,2U37M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS3_k127_2591341_5	1267535.KB906767_gene2392	1.708e-38	149.0	COG1846@1|root,COG1846@2|Bacteria,3Y861@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
MMS3_k127_2591341_4	861299.J421_1010	9.666e-64	224.0	COG3127@1|root,COG3127@2|Bacteria,1ZU3K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2591341_6	452637.Oter_3585	3.209e-37	146.0	COG0589@1|root,COG0589@2|Bacteria,46T7R@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2591341_1	1157490.EL26_06535	9.973e-183	582.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,278YJ@186823|Alicyclobacillaceae	91061|Bacilli	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
MMS3_k127_2591341_2	247490.KSU1_C0752	1.193e-122	409.0	COG1488@1|root,COG1488@2|Bacteria,2IXDA@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
MMS3_k127_2591341_0	644966.Tmar_0394	8.103e-230	723.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248QX@186801|Clostridia	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2591341_3	290397.Adeh_3637	5.257e-96	333.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2YUDA@29|Myxococcales	28221|Deltaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
MMS3_k127_263377_29	357808.RoseRS_2947	1.774e-09	59.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi,375CN@32061|Chloroflexia	32061|Chloroflexia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_263377_17	240015.ACP_2406	3.844e-41	161.0	COG0071@1|root,COG0071@2|Bacteria,3Y4TM@57723|Acidobacteria,2JJFI@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_263377_0	1499967.BAYZ01000026_gene1569	1.486e-279	872.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
MMS3_k127_263377_8	243231.GSU1138	3.97e-101	341.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
MMS3_k127_263377_6	671143.DAMO_0321	4.389e-109	380.0	COG1570@1|root,COG1570@2|Bacteria,2NNQT@2323|unclassified Bacteria	2|Bacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
MMS3_k127_263377_28	1384049.CD29_11785	6.526e-11	69.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,3IYJT@400634|Lysinibacillus	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
MMS3_k127_263377_11	269799.Gmet_1935	5.477e-74	261.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43U3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS3_k127_263377_10	867903.ThesuDRAFT_00081	7.774e-75	263.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WCJM@538999|Clostridiales incertae sedis	186801|Clostridia	J	FtsJ-like methyltransferase	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
MMS3_k127_263377_12	671143.DAMO_0325	2.68e-73	268.0	COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria	2|Bacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
MMS3_k127_263377_9	234267.Acid_7013	6.368e-75	263.0	COG1559@1|root,COG1559@2|Bacteria,3Y2RD@57723|Acidobacteria	57723|Acidobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
MMS3_k127_263377_21	1121456.ATVA01000011_gene1517	1.516e-18	102.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2MBU6@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
MMS3_k127_263377_4	247634.GPB2148_1338	3.817e-135	456.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,1RSAD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
MMS3_k127_263377_19	580340.Tlie_1369	1.219e-22	111.0	COG4942@1|root,COG4942@2|Bacteria,3T9S7@508458|Synergistetes	508458|Synergistetes	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
MMS3_k127_263377_16	671143.DAMO_2530	1.723e-47	185.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
MMS3_k127_263377_20	929713.NIASO_12695	8.788e-22	103.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1IYVW@117747|Sphingobacteriia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMS3_k127_263377_1	1033743.CAES01000004_gene2161	2.827e-208	670.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,26QJC@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
MMS3_k127_263377_14	204669.Acid345_0713	8.062e-60	213.0	COG0290@1|root,COG0290@2|Bacteria,3Y3VP@57723|Acidobacteria,2JIGK@204432|Acidobacteriia	204432|Acidobacteriia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
MMS3_k127_263377_22	498761.HM1_1790	1.755e-17	83.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
MMS3_k127_263377_18	204669.Acid345_0715	1.977e-39	149.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
MMS3_k127_263377_7	880073.Calab_3704	1.14e-107	366.0	COG0016@1|root,COG0016@2|Bacteria,2NNNT@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415,iJN746.PP_2469,iSSON_1240.SSON_1444,iYL1228.KPN_02176	Phe_tRNA-synt_N,tRNA-synt_2d
MMS3_k127_263377_5	264732.Moth_1750	4.642e-130	441.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,42F4K@68295|Thermoanaerobacterales	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
MMS3_k127_263377_27	204669.Acid345_0720	3.615e-12	70.0	COG3027@1|root,COG3027@2|Bacteria,3Y5IJ@57723|Acidobacteria,2JJZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
MMS3_k127_263377_15	243231.GSU3194	1.386e-59	222.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,43UHS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_263377_23	330214.NIDE3048	4.626e-17	91.0	COG3216@1|root,COG3216@2|Bacteria,3J1DC@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
MMS3_k127_263377_24	234267.Acid_4979	2.126e-16	88.0	COG3584@1|root,COG3584@2|Bacteria,3Y8W5@57723|Acidobacteria	57723|Acidobacteria	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
MMS3_k127_263377_2	945713.IALB_2638	1.844e-196	629.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_263377_3	1382359.JIAL01000001_gene1920	1.711e-176	571.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
MMS3_k127_263377_26	1123288.SOV_2c04250	5.052e-14	83.0	29NQS@1|root,309NR@2|Bacteria,1W0AN@1239|Firmicutes,4H873@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_263377_13	926566.Terro_2468	7.986e-71	269.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,3Y2UJ@57723|Acidobacteria,2JIUE@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,YfiO
MMS3_k127_263377_25	240015.ACP_1233	3.755e-15	78.0	COG4974@1|root,COG4974@2|Bacteria,3Y2RA@57723|Acidobacteria,2JHWR@204432|Acidobacteriia	204432|Acidobacteriia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
MMS3_k127_2786764_2	1234364.AMSF01000025_gene3743	1.213e-162	527.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1X5C0@135614|Xanthomonadales	135614|Xanthomonadales	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
MMS3_k127_2786764_1	234267.Acid_7252	1.605e-241	786.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_2786764_0	661478.OP10G_1148	2.417e-265	855.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
MMS3_k127_2786764_3	1380393.JHVP01000003_gene1104	1.14e-140	466.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	2|Bacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
MMS3_k127_2786764_15	1380387.JADM01000001_gene461	1.045e-07	63.0	COG2227@1|root,COG2227@2|Bacteria,1R9ZR@1224|Proteobacteria,1S27B@1236|Gammaproteobacteria,1XRYW@135619|Oceanospirillales	135619|Oceanospirillales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMS3_k127_2786764_9	639030.JHVA01000001_gene2500	5.667e-34	142.0	COG2020@1|root,COG2020@2|Bacteria,3Y53B@57723|Acidobacteria,2JJHM@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMS3_k127_2786764_6	266265.Bxe_C0259	3.498e-49	182.0	COG1335@1|root,COG1335@2|Bacteria,1R8Q8@1224|Proteobacteria,2VITC@28216|Betaproteobacteria,1K32V@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
MMS3_k127_2786764_14	638303.Thal_1145	4.969e-15	81.0	COG4085@1|root,COG4085@2|Bacteria	2|Bacteria	S	PFAM nucleic acid binding, OB-fold, tRNA	yhcR	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	5_nucleotid_C,Gram_pos_anchor,Metallophos,PLDc_2,SNase
MMS3_k127_2786764_5	485918.Cpin_2838	5.269e-57	210.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_2786764_4	266117.Rxyl_0487	4.858e-86	291.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMS3_k127_2786764_11	1279009.ADICEAN_02760	1.878e-23	106.0	COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,47NZT@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_2786764_8	1382304.JNIL01000001_gene2639	8.581e-41	158.0	COG0454@1|root,COG0456@2|Bacteria,1VJPU@1239|Firmicutes,4HXYC@91061|Bacilli,27AFB@186823|Alicyclobacillaceae	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
MMS3_k127_2786764_7	396588.Tgr7_1037	1.026e-45	171.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1WXZ8@135613|Chromatiales	135613|Chromatiales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
MMS3_k127_2786764_12	555779.Dthio_PD0758	2.748e-19	89.0	COG2442@1|root,COG2442@2|Bacteria,1P47Y@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
MMS3_k127_2786764_10	794903.OPIT5_19320	1.118e-33	135.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
MMS3_k127_2786764_13	1411123.JQNH01000001_gene1550	7.644e-17	91.0	2DZ1Z@1|root,34C5P@2|Bacteria,1P6W6@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
MMS3_k127_2834127_31	322710.Avin_29990	1.656e-09	63.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_2834127_13	526224.Bmur_1917	7.067e-38	166.0	COG2604@1|root,COG2604@2|Bacteria,2J5P0@203691|Spirochaetes	203691|Spirochaetes	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
MMS3_k127_2834127_6	1123320.KB889574_gene5716	3.32e-72	258.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,DegT_DnrJ_EryC1,Polysacc_synt_2
MMS3_k127_2834127_9	1382359.JIAL01000001_gene1939	2.591e-49	188.0	COG1360@1|root,COG1360@2|Bacteria,3Y4KZ@57723|Acidobacteria,2JJ8N@204432|Acidobacteriia	204432|Acidobacteriia	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
MMS3_k127_2834127_5	290397.Adeh_1385	1.585e-72	253.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
MMS3_k127_2834127_29	273068.TTE1432	4.509e-10	69.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia,42H8U@68295|Thermoanaerobacterales	186801|Clostridia	N	PFAM flagellar	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
MMS3_k127_2834127_14	573413.Spirs_2931	1.458e-36	152.0	COG1861@1|root,COG1861@2|Bacteria,2J58C@203691|Spirochaetes	203691|Spirochaetes	M	spore coat polysaccharide biosynthesis protein	spsF	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3,Methyltransf_23
MMS3_k127_2834127_4	1385512.N784_05285	2.598e-74	263.0	COG0458@1|root,COG0458@2|Bacteria,1UIGF@1239|Firmicutes,4IUCV@91061|Bacilli	91061|Bacilli	EF	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
MMS3_k127_2834127_7	1122611.KB903951_gene6228	5.665e-64	233.0	COG2089@1|root,COG2089@2|Bacteria,2GJC9@201174|Actinobacteria,4EHAB@85012|Streptosporangiales	201174|Actinobacteria	M	SAF	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
MMS3_k127_2834127_18	748449.Halha_2243	2.483e-26	126.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	ATP-grasp_3,HAD_2
MMS3_k127_2834127_26	882082.SaccyDRAFT_0197	1.657e-12	79.0	COG3980@1|root,COG3980@2|Bacteria,2GMDY@201174|Actinobacteria,4E9PF@85010|Pseudonocardiales	201174|Actinobacteria	M	Spore coat polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_2834127_0	179408.Osc7112_5567	7.5e-125	418.0	COG0399@1|root,COG0399@2|Bacteria,1G4PM@1117|Cyanobacteria,1HFC1@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM DegT DnrJ EryC1 StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_2834127_24	55529.EKX54484	4.972e-15	87.0	KOG2177@1|root,KOG2177@2759|Eukaryota	2759|Eukaryota	O	zinc ion binding	-	-	2.3.2.27	ko:K12035	ko05206,map05206	-	-	-	ko00000,ko00001,ko01000,ko03019,ko04121	-	-	-	NHL
MMS3_k127_2834127_27	644282.Deba_2348	1.056e-10	71.0	2EI2Q@1|root,33BU4@2|Bacteria,1RBKI@1224|Proteobacteria,42R2Y@68525|delta/epsilon subdivisions,2WN31@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2834127_8	429009.Adeg_0252	1.352e-53	217.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,25B5G@186801|Clostridia,42ENC@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Glycos_transf_2,TPR_16,TPR_2,TPR_8
MMS3_k127_2834127_2	195253.Syn6312_0200	2.516e-90	305.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
MMS3_k127_2834127_10	243231.GSU3038	8.198e-48	186.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2WKE1@28221|Deltaproteobacteria,43UIW@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
MMS3_k127_2834127_12	1267535.KB906767_gene4598	9.7e-42	165.0	COG1344@1|root,COG1344@2|Bacteria,3Y4AW@57723|Acidobacteria	57723|Acidobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
MMS3_k127_2834127_21	1120999.JONM01000003_gene2669	2.423e-18	99.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,2KRDS@206351|Neisseriales	206351|Neisseriales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliD_C,FliD_N
MMS3_k127_2834127_20	1123354.AUDR01000019_gene155	1.939e-20	96.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,2VU2S@28216|Betaproteobacteria,1KT6P@119069|Hydrogenophilales	119069|Hydrogenophilales	NOU	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
MMS3_k127_2834127_23	1198114.AciX9_2907	3.195e-15	88.0	COG0454@1|root,COG0456@2|Bacteria,3Y32K@57723|Acidobacteria,2JP2F@204432|Acidobacteriia	204432|Acidobacteriia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_2834127_25	1089548.KI783301_gene2952	4.592e-13	72.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli,3WFWP@539002|Bacillales incertae sedis	91061|Bacilli	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
MMS3_k127_2834127_22	269799.Gmet_0441	3.617e-17	93.0	COG1699@1|root,COG1699@2|Bacteria,1N9E7@1224|Proteobacteria,42V88@68525|delta/epsilon subdivisions,2WR7H@28221|Deltaproteobacteria,43VSM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
MMS3_k127_2834127_28	530564.Psta_2369	1.215e-10	73.0	COG1344@1|root,COG1344@2|Bacteria,2IZMB@203682|Planctomycetes	203682|Planctomycetes	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
MMS3_k127_2834127_11	316067.Geob_0635	5.214e-45	181.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2WMU3@28221|Deltaproteobacteria,43T0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Flagellar basal body rod protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
MMS3_k127_2834127_17	935261.JAGL01000007_gene2527	2.188e-31	136.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,43J93@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	membrane	MA20_30780	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMS3_k127_2834127_1	667014.Thein_0462	5.607e-103	347.0	COG1706@1|root,COG1706@2|Bacteria,2GGRG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
MMS3_k127_2834127_15	933262.AXAM01000005_gene2495	1.498e-34	146.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2WMYI@28221|Deltaproteobacteria,2MIUV@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
MMS3_k127_2834127_30	1005995.GTPT_0929	1.388e-09	68.0	COG1261@1|root,COG1261@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	flgA	-	-	ko:K02279,ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	ChapFlgA,SAF
MMS3_k127_2834127_3	243231.GSU3051	1.643e-89	302.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,42N3R@68525|delta/epsilon subdivisions,2WJDN@28221|Deltaproteobacteria,43TGB@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Flagellar basal body rod FlgEFG protein C-terminal	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
MMS3_k127_2834127_16	240015.ACP_0254	1.157e-33	139.0	COG4786@1|root,COG4786@2|Bacteria,3Y2HI@57723|Acidobacteria,2JIG0@204432|Acidobacteriia	204432|Acidobacteriia	N	Flagella basal body rod protein	-	-	-	ko:K02391,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
MMS3_k127_2834127_32	338966.Ppro_3615	3.944e-07	61.0	COG2804@1|root,COG2804@2|Bacteria,1QXMZ@1224|Proteobacteria,43C42@68525|delta/epsilon subdivisions,2X7EH@28221|Deltaproteobacteria,43TH0@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE_N
MMS3_k127_2834127_19	1267535.KB906767_gene3926	4.65e-24	108.0	COG1886@1|root,COG1886@2|Bacteria,3Y5N4@57723|Acidobacteria	57723|Acidobacteria	NU	Type III flagellar switch regulator (C-ring) FliN C-term	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
MMS3_k127_2842345_8	1121930.AQXG01000001_gene1127	2.704e-106	362.0	COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1IPIY@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	pabB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
MMS3_k127_2842345_2	926550.CLDAP_20900	1.185e-166	554.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMS3_k127_2842345_14	1120973.AQXL01000097_gene902	6.125e-84	293.0	COG3616@1|root,COG3616@2|Bacteria,1TSES@1239|Firmicutes,4HA93@91061|Bacilli,278J8@186823|Alicyclobacillaceae	91061|Bacilli	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
MMS3_k127_2842345_28	484770.UFO1_1121	1.842e-30	126.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,4H4SX@909932|Negativicutes	909932|Negativicutes	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
MMS3_k127_2842345_34	204669.Acid345_1319	3.181e-21	99.0	COG0789@1|root,COG0789@2|Bacteria,3Y5EZ@57723|Acidobacteria,2JN9T@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMS3_k127_2842345_31	383372.Rcas_4347	1.26e-23	106.0	COG2154@1|root,COG2154@2|Bacteria,2G7GN@200795|Chloroflexi,375ZK@32061|Chloroflexia	32061|Chloroflexia	H	PFAM transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
MMS3_k127_2842345_20	671143.DAMO_1161	2.45e-59	219.0	COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19,1.4.5.1	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	-	R01374,R07463,R09493	RC00006,RC00025,RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_2842345_18	926560.KE387023_gene2884	4.684e-67	233.0	COG2318@1|root,COG2318@2|Bacteria,1WMM8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_2842345_15	234267.Acid_4469	4.346e-80	275.0	COG2227@1|root,COG2227@2|Bacteria,3Y2SJ@57723|Acidobacteria	57723|Acidobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2842345_23	1396141.BATP01000023_gene598	1.944e-50	183.0	COG0662@1|root,COG0662@2|Bacteria,46W1W@74201|Verrucomicrobia,2IW0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2842345_35	926550.CLDAP_13510	7.807e-12	69.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_2842345_37	1163409.UUA_09716	6.509e-08	60.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,1RZGS@1236|Gammaproteobacteria,1XBRV@135614|Xanthomonadales	135614|Xanthomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_2842345_4	272560.BPSS0283	4.783e-131	434.0	COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria,2VVCS@28216|Betaproteobacteria,1K2SF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
MMS3_k127_2842345_11	215803.DB30_5754	8.381e-94	314.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,42QYJ@68525|delta/epsilon subdivisions,2WN82@28221|Deltaproteobacteria,2YX3U@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
MMS3_k127_2842345_30	1121918.ARWE01000001_gene180	1.415e-26	120.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,42V21@68525|delta/epsilon subdivisions,2WRFF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
MMS3_k127_2842345_24	1502851.FG93_05458	4.668e-48	178.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2U9MH@28211|Alphaproteobacteria,3JY97@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_2842345_0	234267.Acid_4346	2.232e-223	705.0	COG0154@1|root,COG0154@2|Bacteria,3Y3IP@57723|Acidobacteria	57723|Acidobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS3_k127_2842345_12	379066.GAU_2073	1.565e-88	302.0	COG0008@1|root,COG0008@2|Bacteria,1ZURR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (E and Q), catalytic domain	-	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
MMS3_k127_2842345_1	743722.Sph21_2928	8.962e-202	637.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
MMS3_k127_2842345_10	1123255.JHYS01000004_gene966	3.648e-94	314.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,2VRHY@28216|Betaproteobacteria,4AFE9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
MMS3_k127_2842345_17	243233.MCA0998	9.425e-72	251.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,1S2MJ@1236|Gammaproteobacteria,1XF24@135618|Methylococcales	135618|Methylococcales	S	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
MMS3_k127_2842345_13	215803.DB30_7450	1.275e-87	303.0	COG0451@1|root,COG0451@2|Bacteria,1MXYR@1224|Proteobacteria,438TC@68525|delta/epsilon subdivisions,2X45R@28221|Deltaproteobacteria,2YXQM@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_2842345_33	44056.XP_009034082.1	1.997e-22	113.0	2EN0C@1|root,2SRIN@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2842345_21	856793.MICA_2067	7.45e-54	199.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,4BQD8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS3_k127_2842345_27	932677.PAJ_2342	7.486e-31	133.0	2EYVG@1|root,33S2J@2|Bacteria,1QIIG@1224|Proteobacteria,1TGD8@1236|Gammaproteobacteria,3W1Z6@53335|Pantoea	1236|Gammaproteobacteria	S	N-acetyltransferase	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
MMS3_k127_2842345_3	1379698.RBG1_1C00001G0892	5.862e-139	454.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
MMS3_k127_2842345_38	909663.KI867150_gene1753	0.0005136	48.0	2EK17@1|root,33DRQ@2|Bacteria,1NNYN@1224|Proteobacteria,42WT5@68525|delta/epsilon subdivisions,2WSVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2842345_19	398767.Glov_2398	7.409e-61	230.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42R04@68525|delta/epsilon subdivisions,2WMZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM ATPase, BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
MMS3_k127_2842345_9	398767.Glov_2399	7.888e-95	319.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
MMS3_k127_2842345_6	398767.Glov_2400	4.393e-120	399.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,430HE@68525|delta/epsilon subdivisions,2WVZI@28221|Deltaproteobacteria,43V4N@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
MMS3_k127_2842345_7	398767.Glov_2401	7.623e-109	365.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
MMS3_k127_2842345_25	1244869.H261_03143	1.987e-42	167.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,2UNSE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_2842345_5	1379698.RBG1_1C00001G0907	3.842e-126	413.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539,ko:K18570	ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220	M00541	R05593,R05594,R10696,R10750	RC01430,RC01431,RC03237,RC03270	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_2842345_29	697284.ERIC2_c10060	4.737e-30	125.0	COG3327@1|root,COG3327@2|Bacteria,1TRBU@1239|Firmicutes,4HCP9@91061|Bacilli,275W8@186822|Paenibacillaceae	91061|Bacilli	K	PaaX-like protein	paaX	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
MMS3_k127_2842345_32	1345697.M493_10415	9.32e-23	108.0	COG3327@1|root,COG3327@2|Bacteria,1TRBU@1239|Firmicutes,4HCP9@91061|Bacilli,1WFZV@129337|Geobacillus	91061|Bacilli	K	PaaX-like protein	paaX	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
MMS3_k127_2842345_26	1111069.TCCBUS3UF1_980	8.018e-39	150.0	COG2030@1|root,COG2030@2|Bacteria,1WJC4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
MMS3_k127_286365_6	1288494.EBAPG3_2200	9.203e-28	113.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
MMS3_k127_286365_2	1121405.dsmv_0978	7.983e-139	455.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42MHF@68525|delta/epsilon subdivisions,2WJ1R@28221|Deltaproteobacteria,2MMYC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMS3_k127_286365_1	330214.NIDE3851	2.98e-279	868.0	COG0365@1|root,COG0365@2|Bacteria,3J0BJ@40117|Nitrospirae	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS3_k127_286365_0	639030.JHVA01000001_gene3668	0.0	1088.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y950@57723|Acidobacteria	57723|Acidobacteria	G	PEP-utilising enzyme, mobile domain	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS3_k127_286365_4	472759.Nhal_1647	3.402e-61	217.0	COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,1T3Z1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
MMS3_k127_286365_3	909663.KI867150_gene1086	3.42e-65	229.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_286365_5	1089550.ATTH01000001_gene1139	1.548e-34	139.0	COG2203@1|root,COG3829@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,4PI8P@976|Bacteroidetes,1FIMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS
MMS3_k127_286645_28	649638.Trad_0271	1.144e-08	62.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1WMUT@1297|Deinococcus-Thermus	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	mcpA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HATPase_c,HisKA_3,MCPsignal,PAS_3,PAS_4,PAS_9
MMS3_k127_286645_2	1234364.AMSF01000013_gene633	1.717e-190	614.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1X5B4@135614|Xanthomonadales	135614|Xanthomonadales	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
MMS3_k127_286645_19	1267535.KB906767_gene2875	6.103e-40	164.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria	57723|Acidobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_286645_1	1123277.KB893176_gene3687	1.488e-289	900.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,47JKU@768503|Cytophagia	976|Bacteroidetes	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
MMS3_k127_286645_6	404589.Anae109_1618	3.158e-108	367.0	COG1682@1|root,COG1682@2|Bacteria,1QXTH@1224|Proteobacteria,42XN1@68525|delta/epsilon subdivisions,2WSPR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_286645_4	404589.Anae109_1617	5.469e-112	369.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42ZGK@68525|delta/epsilon subdivisions,2WUTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_286645_16	1122221.JHVI01000004_gene147	4.259e-52	189.0	2CMS6@1|root,32SFE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_286645_11	926560.KE387023_gene2648	3.799e-70	250.0	COG1893@1|root,COG1893@2|Bacteria,1WMJG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_286645_18	1267535.KB906767_gene272	5.859e-50	186.0	2DG4T@1|root,2ZUHN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_286645_9	1382359.JIAL01000001_gene1809	7.814e-89	306.0	COG3391@1|root,COG3391@2|Bacteria,3Y48Y@57723|Acidobacteria,2JJ87@204432|Acidobacteriia	204432|Acidobacteriia	S	YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMS3_k127_286645_3	251221.35211765	8.861e-181	603.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_286645_14	1267535.KB906767_gene213	2.047e-53	192.0	COG1695@1|root,COG1695@2|Bacteria,3Y4NG@57723|Acidobacteria,2JJDN@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_286645_13	861299.J421_5887	1.808e-56	207.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
MMS3_k127_286645_23	404589.Anae109_3080	2.564e-26	115.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WNF6@28221|Deltaproteobacteria,2Z15B@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_286645_5	1313172.YM304_07610	9.868e-110	385.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_286645_17	1123504.JQKD01000030_gene4595	5.224e-52	197.0	COG2207@1|root,COG2207@2|Bacteria,1MXT9@1224|Proteobacteria,2VK2J@28216|Betaproteobacteria,4AF0X@80864|Comamonadaceae	28216|Betaproteobacteria	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
MMS3_k127_286645_21	671143.DAMO_2422	2.15e-27	124.0	28VTP@1|root,2ZHVD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_286645_25	1112212.JH584235_gene2729	6.739e-17	81.0	COG1278@1|root,COG1278@2|Bacteria,1QRMX@1224|Proteobacteria,2V17U@28211|Alphaproteobacteria,2KB7U@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock protein domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD
MMS3_k127_286645_29	196490.AUEZ01000068_gene2503	2.561e-06	60.0	COG3203@1|root,COG3203@2|Bacteria,1MXN6@1224|Proteobacteria,2TSH7@28211|Alphaproteobacteria,3K2QN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Porin subfamily	ropAch1	-	-	-	-	-	-	-	-	-	-	-	Porin_2
MMS3_k127_286645_20	640511.BC1002_1920	3.972e-29	132.0	COG5295@1|root,COG5295@2|Bacteria,1N338@1224|Proteobacteria,2VT5J@28216|Betaproteobacteria,1K4GT@119060|Burkholderiaceae	28216|Betaproteobacteria	UW	Hep_Hag repeat-containing protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	ESPR,YadA_anchor,YadA_head,YadA_stalk
MMS3_k127_286645_26	879309.HMPREF9199_0017	3.593e-15	89.0	COG3501@1|root,COG5295@1|root,COG3501@2|Bacteria,COG5295@2|Bacteria,1VEWB@1239|Firmicutes,4H5RT@909932|Negativicutes	909932|Negativicutes	UW	YadA-like membrane anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	YadA_anchor,YadA_head,YadA_stalk
MMS3_k127_286645_22	1235457.C404_06835	4.209e-27	126.0	COG5295@1|root,COG5295@2|Bacteria,1N338@1224|Proteobacteria,2VT5J@28216|Betaproteobacteria,1K4GT@119060|Burkholderiaceae	28216|Betaproteobacteria	UW	Hep_Hag repeat-containing protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	ESPR,YadA_anchor,YadA_head,YadA_stalk
MMS3_k127_286645_0	240015.ACP_2431	0.0	1125.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y6TN@57723|Acidobacteria,2JK83@204432|Acidobacteriia	204432|Acidobacteriia	EU	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_286645_12	649831.L083_1419	4.576e-58	207.0	COG0454@1|root,COG0454@2|Bacteria,2I66Q@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_286645_15	1205680.CAKO01000006_gene3363	1.511e-52	194.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_286645_8	639030.JHVA01000001_gene2668	1.357e-93	311.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMS3_k127_286645_10	871968.DESME_03620	2.398e-83	289.0	COG5361@1|root,COG5361@2|Bacteria,1V2QH@1239|Firmicutes,24GXZ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1254
MMS3_k127_286645_7	931626.Awo_c06560	7.259e-95	316.0	COG5361@1|root,COG5361@2|Bacteria,1TRC7@1239|Firmicutes,24AHD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
MMS3_k127_2870839_14	631454.N177_0055	2.998e-82	283.0	COG0637@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1877@2|Bacteria,1RGJC@1224|Proteobacteria,2UAPW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
MMS3_k127_2870839_30	1499967.BAYZ01000158_gene441	6.452e-28	121.0	COG2834@1|root,COG2834@2|Bacteria,2NQ6V@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
MMS3_k127_2870839_11	204669.Acid345_1997	2.12e-87	312.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria,2JHZH@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
MMS3_k127_2870839_6	1380390.JIAT01000010_gene4513	1.035e-96	336.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CPCY@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
MMS3_k127_2870839_18	395961.Cyan7425_0898	1.306e-56	210.0	COG0812@1|root,COG0812@2|Bacteria,1FZXZ@1117|Cyanobacteria,3KG32@43988|Cyanothece	1117|Cyanobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
MMS3_k127_2870839_16	867903.ThesuDRAFT_00910	5.962e-80	276.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia	186801|Clostridia	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
MMS3_k127_2870839_19	1410612.JNKO01000002_gene2289	1.502e-55	217.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,24A35@186801|Clostridia,2PRE9@265975|Oribacterium	186801|Clostridia	E	Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
MMS3_k127_2870839_3	589865.DaAHT2_1931	1.888e-127	427.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2MHS5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_2870839_17	1120985.AUMI01000018_gene2990	1.22e-57	212.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4H4GY@909932|Negativicutes	909932|Negativicutes	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
MMS3_k127_2870839_10	290397.Adeh_4264	1.654e-87	302.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2WK5Q@28221|Deltaproteobacteria,2Z31B@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
MMS3_k127_2870839_13	1340493.JNIF01000003_gene2958	3.7e-86	296.0	COG2605@1|root,COG2605@2|Bacteria,3Y56A@57723|Acidobacteria	57723|Acidobacteria	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
MMS3_k127_2870839_31	1278073.MYSTI_03802	4.998e-26	119.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2870839_34	562970.Btus_1597	3.698e-17	91.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,278ID@186823|Alicyclobacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4115)	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
MMS3_k127_2870839_28	562970.Btus_0498	3.74e-29	129.0	COG0352@1|root,COG0352@2|Bacteria,1V6KJ@1239|Firmicutes,4HIM9@91061|Bacilli,278DB@186823|Alicyclobacillaceae	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	-	2.5.1.3,5.3.99.10	ko:K00788,ko:K10810	ko00730,ko01100,map00730,map01100	M00127	R03223,R09977,R10712	RC00224,RC02766,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	TMP-TENI
MMS3_k127_2870839_39	234267.Acid_2564	7.827e-07	60.0	2DTVW@1|root,33MW2@2|Bacteria,3Y606@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2870839_35	204669.Acid345_4380	4.542e-17	93.0	COG0457@1|root,COG2956@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,3Y89N@57723|Acidobacteria	57723|Acidobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
MMS3_k127_2870839_22	1265313.HRUBRA_00829	2.159e-48	185.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1J5VG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
MMS3_k127_2870839_26	1131269.AQVV01000009_gene1141	3.305e-34	139.0	COG0335@1|root,COG0335@2|Bacteria	2|Bacteria	J	large ribosomal subunit rRNA binding	rplS	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
MMS3_k127_2870839_12	1341151.ASZU01000004_gene99	9.815e-87	293.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,27BNR@186824|Thermoactinomycetaceae	91061|Bacilli	J	tRNA (Guanine-1)-methyltransferase	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
MMS3_k127_2870839_27	1440774.Y900_003520	1.026e-29	127.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,238SB@1762|Mycobacteriaceae	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
MMS3_k127_2870839_36	1158345.JNLL01000001_gene65	1.311e-16	87.0	COG1837@1|root,COG1837@2|Bacteria,2G4BD@200783|Aquificae	200783|Aquificae	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
MMS3_k127_2870839_33	1133569.AHYZ01000071_gene702	2.228e-21	98.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
MMS3_k127_2870839_2	867903.ThesuDRAFT_00298	8.21e-154	498.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WCDI@538999|Clostridiales incertae sedis	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
MMS3_k127_2870839_1	635013.TherJR_1781	1.099e-166	537.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,260I8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
MMS3_k127_2870839_21	945713.IALB_2405	5.241e-49	182.0	COG0307@1|root,COG0307@2|Bacteria	2|Bacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU23270	Lum_binding
MMS3_k127_2870839_15	1051632.TPY_0233	4.341e-80	280.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WCD3@538999|Clostridiales incertae sedis	186801|Clostridia	H	Riboflavin biosynthesis protein RibD	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
MMS3_k127_2870839_8	1267535.KB906767_gene4183	1.863e-94	318.0	COG0552@1|root,COG0552@2|Bacteria,3Y3JQ@57723|Acidobacteria,2JIXJ@204432|Acidobacteriia	204432|Acidobacteriia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
MMS3_k127_2870839_9	1382359.JIAL01000001_gene2790	8.798e-91	317.0	COG0240@1|root,COG0240@2|Bacteria,3Y3ZH@57723|Acidobacteria,2JINS@204432|Acidobacteriia	204432|Acidobacteriia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
MMS3_k127_2870839_24	404380.Gbem_0574	1.281e-37	149.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WMZE@28221|Deltaproteobacteria,43UMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
MMS3_k127_2870839_32	1121428.DESHY_60285___1	1.011e-22	107.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,262QN@186807|Peptococcaceae	186801|Clostridia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
MMS3_k127_2870839_7	1047013.AQSP01000094_gene29	1.366e-96	336.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2NP0G@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CinA family	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
MMS3_k127_2870839_29	1267535.KB906767_gene1015	2.505e-28	120.0	COG1267@1|root,COG1267@2|Bacteria,3Y4T1@57723|Acidobacteria	57723|Acidobacteria	I	PFAM Phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
MMS3_k127_2870839_38	1122221.JHVI01000010_gene2499	2.888e-07	62.0	COG1714@1|root,COG1714@2|Bacteria,1WKUI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMS3_k127_2870839_5	555079.Toce_1474	8.452e-102	341.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,42EU0@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Formiminotransferase	ftcD	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
MMS3_k127_2870839_20	204669.Acid345_4041	2.017e-54	211.0	COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria,2JJC7@204432|Acidobacteriia	204432|Acidobacteriia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
MMS3_k127_2870839_23	243231.GSU1488	2.477e-38	158.0	COG0392@1|root,COG0392@2|Bacteria,1N7DR@1224|Proteobacteria,42N4R@68525|delta/epsilon subdivisions,2WS5Z@28221|Deltaproteobacteria,43TTU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMS3_k127_2870839_4	401053.AciPR4_2498	8.041e-114	374.0	COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria,2JIG6@204432|Acidobacteriia	204432|Acidobacteriia	F	SAICAR synthetase	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
MMS3_k127_2870839_37	682795.AciX8_2794	4.57e-12	68.0	COG3829@1|root,COG3829@2|Bacteria,3Y5ZF@57723|Acidobacteria,2JN6W@204432|Acidobacteriia	204432|Acidobacteriia	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
MMS3_k127_2870839_25	706587.Desti_2581	1.147e-36	142.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MS7H@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
MMS3_k127_2870839_0	1267535.KB906767_gene2727	1.425e-222	701.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria,2JIV1@204432|Acidobacteriia	204432|Acidobacteriia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMS3_k127_2931871_3	86416.Clopa_1926	7.855e-14	82.0	COG1266@1|root,COG1266@2|Bacteria,1VVP0@1239|Firmicutes	1239|Firmicutes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_2931871_2	1007103.AFHW01000076_gene5645	1.736e-25	114.0	COG1309@1|root,COG1309@2|Bacteria,1UZQY@1239|Firmicutes,4HEN9@91061|Bacilli,26WY8@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2931871_1	926550.CLDAP_32510	9.216e-59	206.0	COG0735@1|root,COG0735@2|Bacteria,2G9HJ@200795|Chloroflexi	200795|Chloroflexi	P	Ferric uptake regulator family	-	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMS3_k127_2931871_0	1121272.KB903283_gene5142	0.0	1101.0	COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria,4D8UR@85008|Micromonosporales	201174|Actinobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
MMS3_k127_2931871_4	1120954.ATXE01000004_gene232	0.0006995	49.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
MMS3_k127_2966916_0	1121430.JMLG01000005_gene785	1.468e-160	516.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
MMS3_k127_2966916_1	234267.Acid_7201	1.121e-137	452.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_2966916_3	671143.DAMO_2057	4.997e-108	362.0	COG0820@1|root,COG0820@2|Bacteria,2NP4V@2323|unclassified Bacteria	2|Bacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
MMS3_k127_2966916_4	1340493.JNIF01000003_gene4004	1.764e-77	280.0	COG0621@1|root,COG0621@2|Bacteria,3Y41R@57723|Acidobacteria	57723|Acidobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
MMS3_k127_2966916_2	913325.N799_04350	4.817e-131	431.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1X46W@135614|Xanthomonadales	135614|Xanthomonadales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
MMS3_k127_2966916_6	234267.Acid_4371	1.983e-23	100.0	COG0828@1|root,COG0828@2|Bacteria,3Y5J9@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
MMS3_k127_2966916_5	204669.Acid345_1209	5.759e-40	150.0	2DIW1@1|root,32UBV@2|Bacteria,3Y5BC@57723|Acidobacteria,2JJSS@204432|Acidobacteriia	204432|Acidobacteriia	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
MMS3_k127_2992223_0	240015.ACP_0487	1.079e-246	801.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2992223_2	234267.Acid_6173	7.795e-151	482.0	COG1741@1|root,COG1741@2|Bacteria,3Y367@57723|Acidobacteria	57723|Acidobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMS3_k127_2992223_3	661478.OP10G_0811	6.862e-39	146.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
MMS3_k127_2992223_5	880073.Calab_1726	1.588e-06	60.0	28W3K@1|root,2ZI4G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2992223_4	666686.B1NLA3E_08395	9.167e-18	95.0	298S5@1|root,2ZVWF@2|Bacteria,1V8I3@1239|Firmicutes,4HHTT@91061|Bacilli,1ZH6F@1386|Bacillus	91061|Bacilli	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
MMS3_k127_2992223_1	1379270.AUXF01000003_gene3617	1.291e-213	698.0	COG0551@1|root,COG0551@2|Bacteria,1ZUEQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
MMS3_k127_3011949_6	639030.JHVA01000001_gene590	6.455e-29	136.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_3011949_4	1047013.AQSP01000089_gene1180	6.196e-43	177.0	2DQA3@1|root,335JQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3011949_3	1121877.JQKF01000018_gene2547	5.734e-43	168.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4CN1R@84992|Acidimicrobiia	84992|Acidimicrobiia	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3011949_1	1379701.JPJC01000250_gene1511	2.834e-160	527.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2U47T@28211|Alphaproteobacteria,2K2R7@204457|Sphingomonadales	204457|Sphingomonadales	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
MMS3_k127_3011949_2	1038866.KB902773_gene804	8.525e-93	329.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2U3AB@28211|Alphaproteobacteria,3JVN2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	N-terminal domain of ribose phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
MMS3_k127_3011949_0	596154.Alide2_2726	6.656e-185	591.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2VHXI@28216|Betaproteobacteria,4AB63@80864|Comamonadaceae	28216|Betaproteobacteria	F	thymidine phosphorylase	deoA	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
MMS3_k127_3011949_5	278957.ABEA03000010_gene3916	9.971e-32	129.0	COG0614@1|root,COG0614@2|Bacteria,46XU2@74201|Verrucomicrobia,3K9Q9@414999|Opitutae	414999|Opitutae	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
MMS3_k127_3028952_4	240015.ACP_2341	5.988e-125	406.0	COG0040@1|root,COG0040@2|Bacteria,3Y31Q@57723|Acidobacteria,2JICU@204432|Acidobacteriia	204432|Acidobacteriia	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
MMS3_k127_3028952_11	240015.ACP_2342	9.566e-36	139.0	COG0139@1|root,COG0139@2|Bacteria,3Y4SN@57723|Acidobacteria,2JJIB@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	-	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
MMS3_k127_3028952_5	1122604.JONR01000008_gene2124	7.507e-81	277.0	COG0640@1|root,COG0640@2|Bacteria,1MWCW@1224|Proteobacteria,1RRN0@1236|Gammaproteobacteria,1X7NM@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_3028952_10	1472716.KBK24_0111780	9.301e-50	179.0	COG5470@1|root,COG5470@2|Bacteria,1RIH6@1224|Proteobacteria,2VSR7@28216|Betaproteobacteria,1K8VQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
MMS3_k127_3028952_12	204669.Acid345_1548	1.47e-33	134.0	COG3585@1|root,COG3585@2|Bacteria,3Y50T@57723|Acidobacteria,2JJMJ@204432|Acidobacteriia	204432|Acidobacteriia	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,TOBE
MMS3_k127_3028952_9	452637.Oter_3355	1.993e-51	197.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
MMS3_k127_3028952_7	215803.DB30_1633	2.378e-61	220.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42MZE@68525|delta/epsilon subdivisions,2WKJB@28221|Deltaproteobacteria,2Z321@29|Myxococcales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iAF987.Gmet_0512	SBP_bac_11
MMS3_k127_3028952_6	278957.ABEA03000004_gene4545	1.739e-73	258.0	COG4149@1|root,COG4149@2|Bacteria,46TVT@74201|Verrucomicrobia,3K813@414999|Opitutae	414999|Opitutae	P	Molybdate ABC transporter	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
MMS3_k127_3028952_8	215803.DB30_1635	1.533e-53	205.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,42NN3@68525|delta/epsilon subdivisions,2WJZP@28221|Deltaproteobacteria,2YYTX@29|Myxococcales	28221|Deltaproteobacteria	P	TOBE domain	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
MMS3_k127_3028952_3	1047013.AQSP01000097_gene1963	6.083e-136	462.0	COG2091@1|root,COG2091@2|Bacteria,2NQ9X@2323|unclassified Bacteria	2|Bacteria	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
MMS3_k127_3028952_1	234267.Acid_0998	5.422e-185	588.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K08196	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,Sugar_tr
MMS3_k127_3028952_2	1382306.JNIM01000001_gene1966	1.778e-182	583.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
MMS3_k127_3028952_17	1353537.TP2_02875	1.075e-13	79.0	COG3453@1|root,COG3453@2|Bacteria,1MZAJ@1224|Proteobacteria,2UJT4@28211|Alphaproteobacteria,2XKQH@285107|Thioclava	28211|Alphaproteobacteria	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
MMS3_k127_3028952_16	204669.Acid345_3564	8.809e-14	83.0	COG4709@1|root,COG4709@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
MMS3_k127_3028952_13	204669.Acid345_3563	1.974e-29	120.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
MMS3_k127_3028952_15	1340493.JNIF01000003_gene3800	8.774e-15	86.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
MMS3_k127_3028952_18	1123269.NX02_22435	3.652e-05	56.0	2EBPI@1|root,335PM@2|Bacteria,1R3KC@1224|Proteobacteria,2UNS1@28211|Alphaproteobacteria,2K160@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3028952_14	1279009.ADICEAN_02870	1.962e-26	119.0	COG0300@1|root,COG0300@2|Bacteria,4PP7H@976|Bacteroidetes,47YIM@768503|Cytophagia	976|Bacteroidetes	S	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.320	ko:K16216	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
MMS3_k127_3028952_0	234267.Acid_0469	8.597e-321	1000.0	COG1506@1|root,COG1506@2|Bacteria,3Y3DT@57723|Acidobacteria	57723|Acidobacteria	E	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
MMS3_k127_3118120_25	289376.THEYE_A1784	9.751e-21	93.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	MGDG_synth,PHP
MMS3_k127_3118120_4	357808.RoseRS_3857	7.932e-197	633.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,37597@32061|Chloroflexia	32061|Chloroflexia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_3118120_1	1382359.JIAL01000001_gene328	4.715e-251	796.0	COG0068@1|root,COG0068@2|Bacteria,3Y391@57723|Acidobacteria,2JKF7@204432|Acidobacteriia	204432|Acidobacteriia	O	HypF finger	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
MMS3_k127_3118120_15	1382359.JIAL01000001_gene329	6.956e-86	292.0	COG0378@1|root,COG0378@2|Bacteria,3Y3AD@57723|Acidobacteria,2JJ75@204432|Acidobacteriia	204432|Acidobacteriia	KO	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
MMS3_k127_3118120_23	1382359.JIAL01000001_gene330	1.245e-26	118.0	COG0375@1|root,COG0375@2|Bacteria,3Y5WA@57723|Acidobacteria,2JK5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
MMS3_k127_3118120_10	1382359.JIAL01000001_gene331	1.123e-141	458.0	COG0309@1|root,COG0309@2|Bacteria,3Y3UH@57723|Acidobacteria,2JK96@204432|Acidobacteriia	204432|Acidobacteriia	O	AIR synthase related protein, C-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
MMS3_k127_3118120_9	1382359.JIAL01000001_gene332	4.297e-163	521.0	COG0409@1|root,COG0409@2|Bacteria,3Y776@57723|Acidobacteria	57723|Acidobacteria	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
MMS3_k127_3118120_21	240015.ACP_3060	2.963e-27	113.0	COG0298@1|root,COG0298@2|Bacteria,3Y5NM@57723|Acidobacteria,2JK31@204432|Acidobacteriia	204432|Acidobacteriia	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
MMS3_k127_3118120_28	243231.GSU0120	2.625e-16	91.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria,43VTP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
MMS3_k127_3118120_17	1382359.JIAL01000001_gene339	3.753e-69	243.0	COG1969@1|root,COG1969@2|Bacteria	2|Bacteria	C	respiratory electron transport chain	cybH	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
MMS3_k127_3118120_0	240015.ACP_3053	5.435e-271	869.0	COG0374@1|root,COG0374@2|Bacteria,3Y3C2@57723|Acidobacteria,2JJUU@204432|Acidobacteriia	204432|Acidobacteriia	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
MMS3_k127_3118120_8	1382359.JIAL01000001_gene338	4.411e-174	555.0	COG1740@1|root,COG1740@2|Bacteria,3Y3HS@57723|Acidobacteria,2JJYD@204432|Acidobacteriia	204432|Acidobacteriia	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
MMS3_k127_3118120_29	404380.Gbem_1086	3.944e-11	77.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
MMS3_k127_3118120_16	1234364.AMSF01000003_gene2438	3.266e-77	265.0	COG2132@1|root,COG2132@2|Bacteria,1QYH2@1224|Proteobacteria,1S390@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
MMS3_k127_3118120_5	1242864.D187_005861	2.075e-191	616.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YVB7@29|Myxococcales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_3118120_31	1217705.F900_00640	4.489e-07	54.0	2E5S4@1|root,330GM@2|Bacteria,1NAY4@1224|Proteobacteria,1SEIX@1236|Gammaproteobacteria,3NPRS@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3118120_6	234267.Acid_1531	1.397e-185	595.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMS3_k127_3118120_7	215803.DB30_5949	3.122e-183	585.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2YWED@29|Myxococcales	28221|Deltaproteobacteria	U	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMS3_k127_3118120_19	232721.Ajs_0471	3.835e-48	195.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria,4ABSK@80864|Comamonadaceae	28216|Betaproteobacteria	U	SMART AAA ATPase	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
MMS3_k127_3118120_22	502025.Hoch_6858	3.135e-27	121.0	COG0576@1|root,COG0576@2|Bacteria,1QAQQ@1224|Proteobacteria,4358N@68525|delta/epsilon subdivisions,2WZJT@28221|Deltaproteobacteria,2Z2A4@29|Myxococcales	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	-	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
MMS3_k127_3118120_3	314278.NB231_16478	3.642e-228	726.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1WX35@135613|Chromatiales	135613|Chromatiales	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
MMS3_k127_3118120_14	1267533.KB906739_gene2644	4.559e-95	332.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,3Y2RE@57723|Acidobacteria,2JHM7@204432|Acidobacteriia	204432|Acidobacteriia	G	Maltogenic Amylase, C-terminal domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
MMS3_k127_3118120_2	886293.Sinac_2834	1.901e-238	760.0	COG0296@1|root,COG0296@2|Bacteria,2IXPW@203682|Planctomycetes	203682|Planctomycetes	G	Alpha amylase, catalytic domain	-	-	3.2.1.1,3.2.1.141	ko:K01176,ko:K01236	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	M00565	R02108,R02112,R09995,R11256,R11262	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459,S6PP
MMS3_k127_3118120_11	1444711.CCJF01000005_gene196	2.183e-120	413.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2JFD0@204428|Chlamydiae	204428|Chlamydiae	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
MMS3_k127_3118120_30	1150469.RSPPHO_02781	2.563e-07	53.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3118120_26	1267534.KB906754_gene2935	2.652e-20	96.0	COG0582@1|root,COG0582@2|Bacteria,3Y8HK@57723|Acidobacteria	57723|Acidobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS3_k127_3118120_13	375286.mma_0961	1.893e-98	324.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,478J0@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Product type h extrachromosomal origin	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
MMS3_k127_3118120_20	314285.KT71_02322	4.357e-29	121.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
MMS3_k127_3118120_18	1408418.JNJH01000010_gene3490	2.12e-57	209.0	2DM5C@1|root,31SFK@2|Bacteria,1RHYU@1224|Proteobacteria,2UIDQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3118120_24	1499967.BAYZ01000017_gene6258	9.295e-22	112.0	2DTK7@1|root,33KQU@2|Bacteria,2NRAS@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3118120_12	240015.ACP_2487	4.33e-110	366.0	2B47E@1|root,31WYM@2|Bacteria,3Y45I@57723|Acidobacteria,2JIH8@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3118120_27	861299.J421_0285	2.103e-19	91.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0285|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3123937_2	986075.CathTA2_0959	1.05e-266	843.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
MMS3_k127_3123937_27	502025.Hoch_3973	5.988e-63	240.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2YURX@29|Myxococcales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
MMS3_k127_3123937_17	1125863.JAFN01000001_gene3405	1.145e-100	342.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
MMS3_k127_3123937_7	1267533.KB906738_gene2114	4.378e-168	544.0	COG1190@1|root,COG1190@2|Bacteria,3Y3N0@57723|Acidobacteria,2JI1W@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS3_k127_3123937_49	234267.Acid_6222	3.197e-23	115.0	COG0781@1|root,COG0781@2|Bacteria,3Y4Z7@57723|Acidobacteria	57723|Acidobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
MMS3_k127_3123937_38	335543.Sfum_1381	3.292e-43	163.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria,2MQEK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
MMS3_k127_3123937_22	172088.AUGA01000002_gene6122	2.932e-88	299.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VF1S@28211|Alphaproteobacteria,3K6DC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_3123937_56	204669.Acid345_4210	3.602e-05	48.0	2EMVM@1|root,33FHV@2|Bacteria,3Y5YS@57723|Acidobacteria,2JK39@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3123937_50	204669.Acid345_4209	1.03e-20	96.0	2B6R1@1|root,31ZPU@2|Bacteria,3Y4VP@57723|Acidobacteria,2JJGV@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3123937_55	439481.Aboo_1190	2.097e-05	54.0	COG3815@1|root,arCOG03949@2157|Archaea,2Y6YC@28890|Euryarchaeota,3F307@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
MMS3_k127_3123937_14	671143.DAMO_1215	6.394e-110	363.0	COG0524@1|root,COG0524@2|Bacteria,2NP1T@2323|unclassified Bacteria	2|Bacteria	G	pfkB family carbohydrate kinase	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2683	PfkB
MMS3_k127_3123937_13	204669.Acid345_2626	7.562e-120	391.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_3123937_40	292459.STH1188	9.095e-41	163.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,24HPI@186801|Clostridia	186801|Clostridia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	4.4.1.5,5.1.99.1	ko:K01759,ko:K05606	ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00620,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02530,R02765,R09979	RC00004,RC00740,RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
MMS3_k127_3123937_19	529709.PYCH_16980	3.774e-93	315.0	COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,242YC@183968|Thermococci	183968|Thermococci	E	GTPase activity	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
MMS3_k127_3123937_11	204669.Acid345_2369	1.131e-147	479.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3123937_53	314225.ELI_10325	2.181e-13	81.0	COG3239@1|root,COG3239@2|Bacteria,1MUHK@1224|Proteobacteria,2TSTR@28211|Alphaproteobacteria,2K1GV@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
MMS3_k127_3123937_57	1123248.KB893359_gene2175	0.0001251	51.0	2EH8M@1|root,33B0G@2|Bacteria,4NZHR@976|Bacteroidetes,1IZH9@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3123937_23	404380.Gbem_3508	1.719e-84	304.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
MMS3_k127_3123937_31	204669.Acid345_0060	1.768e-57	211.0	COG1484@1|root,COG1484@2|Bacteria,3Y3EK@57723|Acidobacteria,2JI9M@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
MMS3_k127_3123937_26	1047013.AQSP01000077_gene2269	4.861e-64	229.0	COG0568@1|root,COG0568@2|Bacteria,2NQT5@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoS	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_3123937_42	1047013.AQSP01000077_gene2268	2.542e-40	154.0	COG0789@1|root,COG0789@2|Bacteria,2NPTR@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, MerR family	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
MMS3_k127_3123937_20	1267535.KB906767_gene2803	5.063e-91	311.0	COG0484@1|root,COG0484@2|Bacteria,3Y2XW@57723|Acidobacteria,2JHWV@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS3_k127_3123937_1	1499967.BAYZ01000026_gene1569	5.269e-305	945.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
MMS3_k127_3123937_48	290397.Adeh_1548	1.578e-24	117.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria,42UFZ@68525|delta/epsilon subdivisions,2WR5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3123937_6	204669.Acid345_4231	5.648e-183	598.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
MMS3_k127_3123937_12	1382359.JIAL01000001_gene2101	4.605e-131	427.0	COG1186@1|root,COG1186@2|Bacteria,3Y2ZM@57723|Acidobacteria,2JIGW@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMS3_k127_3123937_18	443144.GM21_3259	6.978e-95	335.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
MMS3_k127_3123937_46	234267.Acid_1295	1.207e-25	123.0	COG0457@1|root,COG0457@2|Bacteria,3Y2VC@57723|Acidobacteria	57723|Acidobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
MMS3_k127_3123937_45	401526.TcarDRAFT_0535	2.895e-27	119.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,4H59P@909932|Negativicutes	909932|Negativicutes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
MMS3_k127_3123937_5	1267535.KB906767_gene1458	5.441e-186	603.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
MMS3_k127_3123937_35	309801.trd_1022	3.254e-50	186.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi,27YBG@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
MMS3_k127_3123937_39	1128421.JAGA01000003_gene3505	2.507e-42	172.0	COG2265@1|root,COG2265@2|Bacteria,2NNWX@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
MMS3_k127_3123937_54	204669.Acid345_0137	6.881e-10	68.0	COG3468@1|root,COG3468@2|Bacteria,3Y4NE@57723|Acidobacteria,2JJBC@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3123937_21	671143.DAMO_0664	1.98e-90	304.0	COG1521@1|root,COG1521@2|Bacteria,2NP3Z@2323|unclassified Bacteria	2|Bacteria	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
MMS3_k127_3123937_41	401526.TcarDRAFT_0922	9.147e-41	161.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4H1W3@909932|Negativicutes	909932|Negativicutes	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
MMS3_k127_3123937_24	469383.Cwoe_4594	1.251e-76	277.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4CU2Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Quinolinate phosphoribosyl transferase, C-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
MMS3_k127_3123937_0	1125863.JAFN01000001_gene800	1.47e-319	1002.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
MMS3_k127_3123937_44	1232410.KI421413_gene927	1.45e-28	131.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,43UPW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMS3_k127_3123937_32	204669.Acid345_1432	3.869e-53	201.0	COG2185@1|root,COG2185@2|Bacteria,3Y4YE@57723|Acidobacteria,2JMRD@204432|Acidobacteriia	204432|Acidobacteriia	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
MMS3_k127_3123937_3	204669.Acid345_1454	3.416e-233	733.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria,2JHJN@204432|Acidobacteriia	204432|Acidobacteriia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
MMS3_k127_3123937_8	861299.J421_3227	1.01e-167	539.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
MMS3_k127_3123937_52	1267534.KB906755_gene4541	4.41e-17	96.0	2DBAV@1|root,2Z84I@2|Bacteria,3Y2PF@57723|Acidobacteria,2JIIF@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3123937_9	880073.Calab_0069	9.934e-159	536.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	acdA	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3123937_29	204669.Acid345_4703	2.489e-59	210.0	COG2318@1|root,COG2318@2|Bacteria,3Y4AI@57723|Acidobacteria,2JKRK@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
MMS3_k127_3123937_28	502025.Hoch_3778	7.765e-61	224.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YXAE@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3123937_36	565033.GACE_1690	5.996e-50	184.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,2466N@183980|Archaeoglobi	183980|Archaeoglobi	F	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
MMS3_k127_3123937_43	1267533.KB906735_gene5031	2.96e-35	137.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMS3_k127_3123937_4	290397.Adeh_1520	3.812e-208	662.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
MMS3_k127_3123937_51	56110.Oscil6304_4234	1.36e-17	93.0	2EE59@1|root,337ZW@2|Bacteria,1G955@1117|Cyanobacteria,1HCS4@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3123937_34	479437.Elen_1333	9.947e-51	189.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CV84@84998|Coriobacteriia	84998|Coriobacteriia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
MMS3_k127_3123937_16	215803.DB30_4875	2.977e-109	366.0	COG1073@1|root,COG1073@2|Bacteria,1R4QH@1224|Proteobacteria,43C0C@68525|delta/epsilon subdivisions,2WKKS@28221|Deltaproteobacteria,2Z3EV@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3123937_25	760568.Desku_1862	2.81e-72	252.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,261JB@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMS3_k127_3123937_37	330214.NIDE1418	1.862e-45	175.0	COG1386@1|root,COG1386@2|Bacteria,3J15Z@40117|Nitrospirae	40117|Nitrospirae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
MMS3_k127_3123937_30	243231.GSU1832	1.096e-58	214.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
MMS3_k127_3123937_15	648996.Theam_1168	2.715e-109	365.0	COG0180@1|root,COG0180@2|Bacteria,2G3J1@200783|Aquificae	200783|Aquificae	J	Tryptophanyl-tRNA synthetase	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
MMS3_k127_3123937_10	1382359.JIAL01000001_gene2381	8.229e-149	493.0	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria,2JI6E@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
MMS3_k127_3123937_33	1267535.KB906767_gene3789	7.443e-52	190.0	COG0558@1|root,COG0558@2|Bacteria,3Y427@57723|Acidobacteria,2JID7@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_3123937_47	234267.Acid_5441	1.152e-24	112.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_32362_4	635013.TherJR_1923	1.19e-196	629.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
MMS3_k127_32362_20	330214.NIDE4089	1.906e-115	380.0	COG1702@1|root,COG1702@2|Bacteria,3J0AD@40117|Nitrospirae	40117|Nitrospirae	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
MMS3_k127_32362_65	240015.ACP_1699	1.057e-24	119.0	COG0319@1|root,COG0319@2|Bacteria,3Y53R@57723|Acidobacteria,2JJPS@204432|Acidobacteriia	204432|Acidobacteriia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
MMS3_k127_32362_50	525904.Tter_0015	3.709e-57	216.0	COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	tlyC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
MMS3_k127_32362_32	429009.Adeg_0138	2.619e-85	293.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,42EK1@68295|Thermoanaerobacterales	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
MMS3_k127_32362_18	1047013.AQSP01000072_gene988	1.613e-118	396.0	COG2239@1|root,COG2239@2|Bacteria,2NP6V@2323|unclassified Bacteria	2|Bacteria	P	Acts as a magnesium transporter	mgtE	GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511	3.6.1.1	ko:K03281,ko:K04767,ko:K06213,ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000,ko02000	1.A.26.1,2.A.49	-	iYO844.BSU13300	CBS,MgtE,MgtE_N
MMS3_k127_32362_61	1267533.KB906737_gene1626	1.662e-31	133.0	COG1381@1|root,COG1381@2|Bacteria,3Y4AX@57723|Acidobacteria,2JJ0T@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
MMS3_k127_32362_23	404589.Anae109_2460	2.348e-112	370.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria,2YTSG@29|Myxococcales	28221|Deltaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
MMS3_k127_32362_17	1123371.ATXH01000022_gene993	2.009e-124	426.0	COG0751@1|root,COG0751@2|Bacteria,2GH99@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
MMS3_k127_32362_1	1047013.AQSP01000132_gene1748	0.0	1077.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.3.13,2.7.9.1	ko:K01006,ko:K22424	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS3_k127_32362_16	204669.Acid345_3219	2.576e-125	422.0	COG0323@1|root,COG0323@2|Bacteria,3Y2T3@57723|Acidobacteria,2JI29@204432|Acidobacteriia	204432|Acidobacteriia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
MMS3_k127_32362_10	479434.Sthe_0425	1.326e-153	498.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,27XS9@189775|Thermomicrobia	189775|Thermomicrobia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
MMS3_k127_32362_59	498761.HM1_1794	2.778e-35	147.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
MMS3_k127_32362_53	682795.AciX8_4862	1.33e-46	172.0	COG0782@1|root,COG0782@2|Bacteria,3Y49X@57723|Acidobacteria,2JJ1A@204432|Acidobacteriia	204432|Acidobacteriia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
MMS3_k127_32362_74	525909.Afer_0074	0.0001351	54.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4CNDE@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMS3_k127_32362_24	1379698.RBG1_1C00001G1614	7.701e-108	362.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_32362_33	1125863.JAFN01000001_gene1090	3.324e-84	297.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
MMS3_k127_32362_2	240015.ACP_2786	1.775e-287	897.0	COG0556@1|root,COG0556@2|Bacteria,3Y31K@57723|Acidobacteria,2JHY9@204432|Acidobacteriia	204432|Acidobacteriia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
MMS3_k127_32362_38	1382359.JIAL01000001_gene2412	1.256e-72	253.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
MMS3_k127_32362_43	204669.Acid345_2891	1.742e-69	245.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
MMS3_k127_32362_56	1232410.KI421421_gene3419	3.01e-38	157.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43UDZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
MMS3_k127_32362_71	589865.DaAHT2_1072	5.411e-09	63.0	COG4980@1|root,COG4980@2|Bacteria,1NB49@1224|Proteobacteria,42W0M@68525|delta/epsilon subdivisions,2WRVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
MMS3_k127_32362_51	696281.Desru_1270	1.621e-49	182.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
MMS3_k127_32362_46	1444309.JAQG01000080_gene4010	7.108e-61	220.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,26QH3@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835,iYO844.BSU39420	DeoC
MMS3_k127_32362_14	469383.Cwoe_3174	5.766e-131	444.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CPEU@84995|Rubrobacteria	84995|Rubrobacteria	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_32362_30	383372.Rcas_3282	1.218e-88	304.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,376T2@32061|Chloroflexia	32061|Chloroflexia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
MMS3_k127_32362_55	1047013.AQSP01000105_gene1462	5.471e-40	168.0	COG0558@1|root,COG0558@2|Bacteria,2NPJ9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iIT341.HP1016	CDP-OH_P_transf
MMS3_k127_32362_69	460265.Mnod_7434	4.402e-15	85.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,1JSD0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
MMS3_k127_32362_19	1499967.BAYZ01000176_gene5652	3.576e-117	387.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	ytcB	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
MMS3_k127_32362_62	452637.Oter_4018	5.919e-31	130.0	COG0824@1|root,COG0824@2|Bacteria,46VV8@74201|Verrucomicrobia,3K85G@414999|Opitutae	414999|Opitutae	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
MMS3_k127_32362_40	330214.NIDE0397	1.432e-71	253.0	COG0036@1|root,COG0036@2|Bacteria,3J0IZ@40117|Nitrospirae	40117|Nitrospirae	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
MMS3_k127_32362_68	1321786.HMPREF1992_02249	2.758e-15	85.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
MMS3_k127_32362_31	760568.Desku_1315	1.692e-88	308.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,2614J@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
MMS3_k127_32362_34	396588.Tgr7_0196	8.282e-83	296.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1WWQE@135613|Chromatiales	135613|Chromatiales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
MMS3_k127_32362_54	1382359.JIAL01000001_gene476	3.72e-44	177.0	COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria,2JJ9D@204432|Acidobacteriia	204432|Acidobacteriia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
MMS3_k127_32362_21	1121946.AUAX01000008_gene7204	3.451e-114	380.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4DAFR@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
MMS3_k127_32362_39	290397.Adeh_0417	4.167e-72	278.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YX5F@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	nla19	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_32362_60	639030.JHVA01000001_gene1962	7.078e-35	141.0	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria,2JJ89@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_32362_13	234267.Acid_0265	7.406e-132	448.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
MMS3_k127_32362_28	1047013.AQSP01000140_gene2527	1.219e-95	337.0	COG1044@1|root,COG1044@2|Bacteria,2NQT1@2323|unclassified Bacteria	2|Bacteria	M	SpoIVB peptidase S55	-	-	2.7.7.24	ko:K00973,ko:K02414,ko:K21449	ko00521,ko00523,ko00525,ko01130,ko02040,map00521,map00523,map00525,map01130,map02040	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000,ko02035	1.B.40.2	-	-	AMP-binding,APH,DUF4114,DUF4842,Hexapep,PP-binding,Peptidase_S55
MMS3_k127_32362_37	237368.SCABRO_03813	1.511e-73	267.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2IXKU@203682|Planctomycetes	203682|Planctomycetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
MMS3_k127_32362_9	574087.Acear_1870	2.337e-154	502.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3WBGE@53433|Halanaerobiales	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
MMS3_k127_32362_35	240015.ACP_2879	4.561e-78	265.0	COG0512@1|root,COG0512@2|Bacteria,3Y36D@57723|Acidobacteria,2JHQS@204432|Acidobacteriia	204432|Acidobacteriia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMS3_k127_32362_25	644966.Tmar_1454	6.06e-104	348.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3WCZN@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
MMS3_k127_32362_47	935863.AWZR01000001_gene2084	7.673e-61	222.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1X42P@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
MMS3_k127_32362_52	1125863.JAFN01000001_gene2403	3.848e-49	183.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
MMS3_k127_32362_8	478741.JAFS01000002_gene375	1.438e-164	529.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,37G1U@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_32362_42	56780.SYN_01941	8.282e-70	246.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,2MQGB@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
MMS3_k127_32362_11	234267.Acid_7885	6.831e-143	462.0	COG2876@1|root,COG2876@2|Bacteria,3Y2SV@57723|Acidobacteria	57723|Acidobacteria	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
MMS3_k127_32362_27	1379698.RBG1_1C00001G1461	4.582e-100	331.0	COG1788@1|root,COG1788@2|Bacteria,2NPDX@2323|unclassified Bacteria	2|Bacteria	I	Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01034	ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
MMS3_k127_32362_29	240015.ACP_0929	1.43e-94	314.0	COG2057@1|root,COG2057@2|Bacteria,3Y3EC@57723|Acidobacteria,2JIV4@204432|Acidobacteriia	204432|Acidobacteriia	I	Coenzyme A transferase	-	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
MMS3_k127_32362_12	1536769.P40081_25255	7.364e-134	448.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,26RP3@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_32362_66	1219035.NT2_05_03100	7.72e-21	98.0	COG1310@1|root,COG1310@2|Bacteria,1NC23@1224|Proteobacteria,2UGM4@28211|Alphaproteobacteria,2K62I@204457|Sphingomonadales	204457|Sphingomonadales	L	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
MMS3_k127_32362_0	240015.ACP_1634	0.0	1176.0	COG1505@1|root,COG1505@2|Bacteria,3Y2UH@57723|Acidobacteria,2JHQ3@204432|Acidobacteriia	204432|Acidobacteriia	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
MMS3_k127_32362_22	1340493.JNIF01000004_gene57	1.902e-113	385.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria	57723|Acidobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
MMS3_k127_32362_36	639030.JHVA01000001_gene2991	1.279e-74	282.0	COG0860@1|root,COG0860@2|Bacteria,3Y3M0@57723|Acidobacteria,2JI9V@204432|Acidobacteriia	204432|Acidobacteriia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
MMS3_k127_32362_6	1382359.JIAL01000001_gene136	1.495e-187	617.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria,2JHRN@204432|Acidobacteriia	204432|Acidobacteriia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
MMS3_k127_32362_7	234267.Acid_4486	8.201e-178	577.0	COG0595@1|root,COG0595@2|Bacteria,3Y2NH@57723|Acidobacteria	57723|Acidobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
MMS3_k127_32362_45	1279019.ARQK01000050_gene1337	5.108e-61	221.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales	135613|Chromatiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
MMS3_k127_32362_64	443255.SCLAV_3119	4.391e-25	111.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
MMS3_k127_32362_44	1122130.AUHN01000009_gene693	1.092e-61	220.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
MMS3_k127_32362_76	1519464.HY22_09940	0.0007445	47.0	COG4191@1|root,COG4191@2|Bacteria,1FFJ1@1090|Chlorobi	1090|Chlorobi	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
MMS3_k127_32362_41	1379270.AUXF01000006_gene164	2.463e-70	259.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
MMS3_k127_32362_48	234267.Acid_4808	9.296e-61	222.0	COG0524@1|root,COG0524@2|Bacteria,3Y659@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.184	ko:K18478	-	-	R10970	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
MMS3_k127_32362_57	671143.DAMO_2841	2.662e-36	147.0	COG1595@1|root,COG1595@2|Bacteria,2NPR9@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_32362_73	682795.AciX8_4226	2.93e-05	53.0	COG5660@1|root,COG5660@2|Bacteria,3Y556@57723|Acidobacteria,2JJU3@204432|Acidobacteriia	204432|Acidobacteriia	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_32362_70	234267.Acid_4931	4.275e-09	66.0	2FIDY@1|root,34A64@2|Bacteria,3Y8PB@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_32362_5	234267.Acid_7763	2.236e-193	625.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria	57723|Acidobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
MMS3_k127_32362_63	1297742.A176_01474	5.011e-30	133.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,2YVK3@29|Myxococcales	28221|Deltaproteobacteria	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
MMS3_k127_32362_49	234267.Acid_7275	3.414e-60	214.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria	57723|Acidobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS3_k127_32362_26	429009.Adeg_1380	5.53e-102	354.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
MMS3_k127_32362_15	879212.DespoDRAFT_02932	4.913e-130	432.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2MI3F@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM FAD linked oxidase domain protein	larD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3245	FAD-oxidase_C,FAD_binding_4
MMS3_k127_32362_58	344747.PM8797T_00025	1.027e-35	140.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
MMS3_k127_32362_3	1267535.KB906767_gene3177	5.652e-229	718.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
MMS3_k127_32362_67	204669.Acid345_3258	6.051e-16	79.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria,2JJXU@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
MMS3_k127_3273333_1	234267.Acid_4582	3.773e-265	836.0	COG2234@1|root,COG2234@2|Bacteria,3Y435@57723|Acidobacteria	57723|Acidobacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
MMS3_k127_3273333_19	194439.CT2087	4.194e-48	181.0	COG0400@1|root,COG0400@2|Bacteria,1FF1R@1090|Chlorobi	1090|Chlorobi	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
MMS3_k127_3273333_20	1120959.ATXF01000005_gene1010	3.943e-43	170.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4FPN5@85023|Microbacteriaceae	201174|Actinobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
MMS3_k127_3273333_22	234267.Acid_3785	1.466e-27	123.0	COG2823@1|root,COG2823@2|Bacteria,3Y4KR@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
MMS3_k127_3273333_18	7370.XP_005188234.1	8.736e-76	263.0	COG1028@1|root,KOG0725@2759|Eukaryota,38BUC@33154|Opisthokonta,3BC34@33208|Metazoa,3D09G@33213|Bilateria,41TU2@6656|Arthropoda,3SZ4C@50557|Insecta,454Z1@7147|Diptera	33208|Metazoa	Q	Oxidoreductase activity. It is involved in the biological process described with metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3273333_27	1142394.PSMK_30520	0.0003849	54.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS3_k127_3273333_3	204669.Acid345_2392	9.95e-205	644.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria,2JIPN@204432|Acidobacteriia	204432|Acidobacteriia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
MMS3_k127_3273333_24	1047013.AQSP01000090_gene672	7.526e-17	87.0	2DF8J@1|root,2ZQXQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3273333_0	1382356.JQMP01000004_gene583	1.902e-296	923.0	COG0365@1|root,COG0365@2|Bacteria,2G5KE@200795|Chloroflexi,27XEK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS3_k127_3273333_23	1395587.P364_0107635	1.224e-19	103.0	COG2199@1|root,COG3290@1|root,COG3290@2|Bacteria,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,4HQBN@91061|Bacilli,26SIT@186822|Paenibacillaceae	91061|Bacilli	T	N-terminal 7TM region of histidine kinase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	5TM-5TMR_LYT,GGDEF,HisKA_7TM,dCache_1
MMS3_k127_3273333_6	401526.TcarDRAFT_1563	3.426e-154	510.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
MMS3_k127_3273333_26	1173029.JH980292_gene3255	1.178e-08	65.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,1G30V@1117|Cyanobacteria,1H8NG@1150|Oscillatoriales	1117|Cyanobacteria	O	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_1,TPR_11,TPR_2,TPR_8
MMS3_k127_3273333_13	1267535.KB906767_gene3077	9.981e-108	353.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3273333_16	1123284.KB899049_gene1880	2.136e-89	330.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,26NGG@186821|Sporolactobacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
MMS3_k127_3273333_12	867903.ThesuDRAFT_01537	3.85e-108	360.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
MMS3_k127_3273333_2	592015.HMPREF1705_01943	4.595e-214	678.0	COG1884@1|root,COG1884@2|Bacteria,3T9QP@508458|Synergistetes	508458|Synergistetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
MMS3_k127_3273333_10	234267.Acid_4374	4.71e-117	388.0	COG0588@1|root,COG0588@2|Bacteria,3Y6SZ@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
MMS3_k127_3273333_5	404589.Anae109_2168	4.767e-162	523.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2YWXC@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMS3_k127_3273333_7	330214.NIDE1796	1.614e-150	490.0	COG0448@1|root,COG0448@2|Bacteria,3J0BI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_3273333_25	682795.AciX8_3035	1.612e-10	72.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia	204432|Acidobacteriia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3273333_28	1297742.A176_03641	0.0005664	53.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42NGM@68525|delta/epsilon subdivisions,2WKKR@28221|Deltaproteobacteria,2YUPA@29|Myxococcales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
MMS3_k127_3273333_4	204669.Acid345_3357	1.494e-179	598.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
MMS3_k127_3273333_8	204669.Acid345_3356	2.271e-144	475.0	COG2204@1|root,COG2204@2|Bacteria,3Y3T2@57723|Acidobacteria,2JIG9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3273333_11	1499967.BAYZ01000038_gene2273	1.472e-109	368.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
MMS3_k127_3273333_17	1047013.AQSP01000140_gene2463	5.54e-78	278.0	COG0438@1|root,COG0438@2|Bacteria,2NQE7@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_3273333_15	1047013.AQSP01000140_gene2462	4.698e-95	326.0	COG0438@1|root,COG0438@2|Bacteria,2NQE7@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_3273333_9	1047013.AQSP01000140_gene2461	1.15e-132	437.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
MMS3_k127_3273333_14	1499967.BAYZ01000193_gene3921	2.377e-95	323.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
MMS3_k127_3273333_21	1340493.JNIF01000003_gene4350	2.16e-36	141.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria	57723|Acidobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
MMS3_k127_3325762_23	1415780.JPOG01000001_gene1179	1.889e-85	297.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1X36A@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
MMS3_k127_3325762_55	378806.STAUR_7590	2.164e-26	115.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,SpoIIE
MMS3_k127_3325762_28	398767.Glov_0416	1.495e-72	259.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
MMS3_k127_3325762_66	861299.J421_1377	5.69e-09	67.0	2EQJ9@1|root,33I5A@2|Bacteria,1ZTSN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3325762_46	446470.Snas_2963	3.047e-35	153.0	COG0463@1|root,COG1287@1|root,COG0463@2|Bacteria,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
MMS3_k127_3325762_58	240015.ACP_1908	4.9e-19	95.0	COG1238@1|root,COG1238@2|Bacteria,3Y52F@57723|Acidobacteria,2JJK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_3325762_15	671143.DAMO_1634	2.691e-106	357.0	COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	arnC	GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
MMS3_k127_3325762_63	246197.MXAN_2876	1.031e-11	77.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,1NNV4@1224|Proteobacteria,42Q3S@68525|delta/epsilon subdivisions,2WMM2@28221|Deltaproteobacteria,2Z1Q8@29|Myxococcales	28221|Deltaproteobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3325762_52	419665.Maeo_0391	2.661e-31	138.0	COG2244@1|root,arCOG02209@2157|Archaea,2XSUR@28890|Euryarchaeota,23QGV@183939|Methanococci	183939|Methanococci	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
MMS3_k127_3325762_48	1000565.METUNv1_03767	6.372e-33	143.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,2VJET@28216|Betaproteobacteria	28216|Betaproteobacteria	M	glycosyl transferase group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1,Kdo
MMS3_k127_3325762_36	313612.L8106_08561	8.915e-56	209.0	COG1216@1|root,COG1216@2|Bacteria,1GCX3@1117|Cyanobacteria,1HE8C@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3325762_37	329726.AM1_2715	9.412e-51	196.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_3325762_40	1499967.BAYZ01000005_gene5436	3.227e-46	188.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NQY2@2323|unclassified Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT,PMT_2,TPR_19
MMS3_k127_3325762_47	489825.LYNGBM3L_22570	7.817e-34	143.0	COG0392@1|root,COG0392@2|Bacteria,1G41A@1117|Cyanobacteria,1HD8Q@1150|Oscillatoriales	1117|Cyanobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMS3_k127_3325762_17	1499967.BAYZ01000195_gene3102	4.692e-100	341.0	COG0438@1|root,COG0438@2|Bacteria,2NQRB@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_3325762_60	156889.Mmc1_3517	1.835e-16	91.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Glycos_transf_2,HTH_20,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
MMS3_k127_3325762_19	1142394.PSMK_04130	2.865e-95	328.0	COG0451@1|root,COG0451@2|Bacteria,2IYS9@203682|Planctomycetes	203682|Planctomycetes	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_3325762_32	766499.C357_23070	8.047e-63	236.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
MMS3_k127_3325762_34	316274.Haur_0775	2.092e-61	225.0	COG0438@1|root,COG0438@2|Bacteria,2G7XU@200795|Chloroflexi,3755Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_3325762_26	443143.GM18_3738	1.08e-80	278.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,43TI0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
MMS3_k127_3325762_38	338963.Pcar_3070	1.416e-48	191.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,43SKN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	D-Tyr-tRNA(Tyr) deacylase	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
MMS3_k127_3325762_64	1379698.RBG1_1C00001G0758	1.376e-10	72.0	2ER9F@1|root,33IV2@2|Bacteria,2NRV9@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3325762_18	489825.LYNGBM3L_22490	2.558e-96	336.0	COG0578@1|root,COG0578@2|Bacteria,1G1T3@1117|Cyanobacteria,1H86N@1150|Oscillatoriales	1117|Cyanobacteria	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
MMS3_k127_3325762_54	1121403.AUCV01000022_gene3504	2.047e-29	127.0	COG2227@1|root,COG2227@2|Bacteria,1R11D@1224|Proteobacteria,42RT6@68525|delta/epsilon subdivisions,2WNH2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Nodulation protein S (NodS)	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
MMS3_k127_3325762_39	477974.Daud_1604	2.252e-46	178.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,260JZ@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
MMS3_k127_3325762_13	706587.Desti_0932	1.203e-117	397.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Sodium sulphate symporter	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
MMS3_k127_3325762_35	1356854.N007_03915	5.038e-57	205.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,2789Y@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
MMS3_k127_3325762_16	204669.Acid345_2031	2.913e-102	349.0	COG1641@1|root,COG1641@2|Bacteria,3Y42R@57723|Acidobacteria,2JI6G@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
MMS3_k127_3325762_10	370438.PTH_0069	7.491e-141	463.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,2613N@186807|Peptococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
MMS3_k127_3325762_49	1382359.JIAL01000001_gene119	2.534e-32	134.0	COG0143@1|root,COG0143@2|Bacteria,3Y2I2@57723|Acidobacteria,2JIC5@204432|Acidobacteriia	204432|Acidobacteriia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
MMS3_k127_3325762_31	713586.KB900536_gene669	4.291e-64	233.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1WXA1@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
MMS3_k127_3325762_24	1125863.JAFN01000001_gene236	1.968e-82	285.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS3_k127_3325762_45	584708.Apau_2405	5.274e-38	160.0	COG2110@1|root,COG2110@2|Bacteria,3TB5Z@508458|Synergistetes	508458|Synergistetes	S	C-terminal domain of histone	-	-	-	-	-	-	-	-	-	-	-	-	Macro
MMS3_k127_3325762_67	1340493.JNIF01000004_gene178	4.586e-08	64.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10,Reprolysin_3
MMS3_k127_3325762_3	1121468.AUBR01000017_gene2369	1.965e-221	706.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,42F6C@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMS3_k127_3325762_22	215803.DB30_4926	2.334e-87	307.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YYCB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_3325762_7	1047013.AQSP01000123_gene1542	9.13e-162	522.0	COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3325762_62	224914.BMEI0568	6.234e-13	72.0	2ENFV@1|root,33G39@2|Bacteria,1NP5K@1224|Proteobacteria,2UJUH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3325762_14	1125863.JAFN01000001_gene322	2.141e-111	369.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
MMS3_k127_3325762_33	379066.GAU_2187	3.474e-62	218.0	COG0431@1|root,COG0431@2|Bacteria,1ZUYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
MMS3_k127_3325762_59	370438.PTH_0854	1.719e-16	89.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,262CC@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
MMS3_k127_3325762_29	1121918.ARWE01000001_gene2001	1.398e-69	255.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3325762_11	671143.DAMO_0704	1.503e-128	421.0	COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
MMS3_k127_3325762_42	1111479.AXAR01000015_gene1290	4.477e-43	160.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,279UB@186823|Alicyclobacillaceae	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
MMS3_k127_3325762_0	1144275.COCOR_05001	0.0	1216.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,42MR9@68525|delta/epsilon subdivisions,2WIP3@28221|Deltaproteobacteria,2YUNJ@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
MMS3_k127_3325762_30	644966.Tmar_2150	1.744e-67	241.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,3WDJY@538999|Clostridiales incertae sedis	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_3325762_12	671143.DAMO_1556	3.083e-128	427.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
MMS3_k127_3325762_53	518766.Rmar_2519	1.399e-30	127.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1FJHQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
MMS3_k127_3325762_4	1120792.JAFV01000001_gene843	9.453e-182	583.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,36X6V@31993|Methylocystaceae	28211|Alphaproteobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205,1.7.1.7	ko:K00088,ko:K00364	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R01134,R08240	RC00143,RC00457,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
MMS3_k127_3325762_1	234267.Acid_4491	0.0	1128.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria	57723|Acidobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
MMS3_k127_3325762_43	363253.LI0920	1.231e-39	159.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMS3_k127_3325762_27	1267535.KB906767_gene5295	1.477e-79	280.0	COG3391@1|root,COG3391@2|Bacteria,3Y48Y@57723|Acidobacteria,2JJ87@204432|Acidobacteriia	204432|Acidobacteriia	S	YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3325762_5	1218074.BAXZ01000004_gene968	3.066e-165	533.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2VNS4@28216|Betaproteobacteria,1K4VU@119060|Burkholderiaceae	28216|Betaproteobacteria	E	amino acid peptide transporter	dtpA	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
MMS3_k127_3325762_68	381666.H16_A0057	5.281e-08	63.0	2DKFZ@1|root,309D6@2|Bacteria,1QZK6@1224|Proteobacteria,2WHMG@28216|Betaproteobacteria,1KINP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
MMS3_k127_3325762_73	305700.B447_00310	0.0003983	51.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,2VVPQ@28216|Betaproteobacteria,2KXGS@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
MMS3_k127_3325762_71	1160707.AJIK01000001_gene270	4.361e-05	56.0	COG3156@1|root,COG3156@2|Bacteria,1UYI3@1239|Firmicutes,4HDN1@91061|Bacilli,26FBE@186818|Planococcaceae	91061|Bacilli	U	type II secretion system protein K	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
MMS3_k127_3325762_9	1038869.AXAN01000081_gene2941	2.045e-141	464.0	COG1215@1|root,COG1215@2|Bacteria,1MXXV@1224|Proteobacteria,2VZ3D@28216|Betaproteobacteria,1K61T@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Chitin synthase	-	-	-	ko:K14666	-	M00664	-	-	ko00000,ko00002,ko01000,ko01003	-	GT2	-	Glycos_transf_2
MMS3_k127_3325762_6	309801.trd_A0017	5.808e-163	530.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
MMS3_k127_3325762_56	1131269.AQVV01000011_gene2530	3.732e-24	120.0	2F5UG@1|root,33YDE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3325762_20	204669.Acid345_0549	5.418e-93	335.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y38S@57723|Acidobacteria,2JHZB@204432|Acidobacteriia	204432|Acidobacteriia	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
MMS3_k127_3325762_8	1121472.AQWN01000001_gene65	8.171e-153	503.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,260WN@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM acetaldehyde dehydrogenase (acetylating)	-	-	1.2.1.10	ko:K00132	ko00620,ko00650,ko01100,ko01120,map00620,map00650,map01100,map01120	-	R00228,R01172	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMS3_k127_3325762_44	929506.CbC4_1724	1.433e-39	149.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae	186801|Clostridia	CQ	PFAM microcompartments protein	NPD7_940	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
MMS3_k127_3325762_51	1125863.JAFN01000001_gene3191	5.238e-32	134.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
MMS3_k127_3325762_25	243231.GSU1784	2.852e-81	285.0	COG1459@1|root,COG1459@2|Bacteria,1N8FA@1224|Proteobacteria,42SJG@68525|delta/epsilon subdivisions,2WP9K@28221|Deltaproteobacteria,43T1M@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein F	pulF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
MMS3_k127_3325762_2	204669.Acid345_1576	2.146e-225	730.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
MMS3_k127_3325762_61	234267.Acid_0046	3.37e-14	87.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria	57723|Acidobacteria	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
MMS3_k127_3325762_69	1340493.JNIF01000003_gene1706	1.376e-06	57.0	COG3166@1|root,COG3166@2|Bacteria,3Y4GJ@57723|Acidobacteria	57723|Acidobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
MMS3_k127_3325762_72	1198114.AciX9_0949	5.867e-05	54.0	2C8FF@1|root,333TN@2|Bacteria,3Y5GA@57723|Acidobacteria,2JJYB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3325762_21	204669.Acid345_1997	6.76e-91	327.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria,2JHZH@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
MMS3_k127_3325762_41	639030.JHVA01000001_gene638	2.443e-44	167.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria,2JJB4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
MMS3_k127_3325762_50	443144.GM21_2997	5.125e-32	129.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria	1224|Proteobacteria	U	type II secretion system protein G	oxpG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
MMS3_k127_3325762_70	105420.BBPO01000033_gene3761	3.081e-06	56.0	COG2247@1|root,COG5640@1|root,COG2247@2|Bacteria,COG5640@2|Bacteria,2IATB@201174|Actinobacteria,2NNBF@228398|Streptacidiphilus	201174|Actinobacteria	MO	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
MMS3_k127_3334007_12	1216932.CM240_1658	5.072e-06	56.0	COG0297@1|root,COG0297@2|Bacteria,1UMSQ@1239|Firmicutes,25H65@186801|Clostridia,36V95@31979|Clostridiaceae	186801|Clostridia	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_3334007_8	383372.Rcas_4314	1.401e-32	141.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_3334007_7	460265.Mnod_8763	4.086e-33	138.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	ko:K16648	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Methyltransf_11
MMS3_k127_3334007_3	1121447.JONL01000003_gene3192	7.32e-71	264.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MANW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_3334007_5	1121447.JONL01000003_gene3191	6.272e-70	259.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,42WA6@68525|delta/epsilon subdivisions,2WRYV@28221|Deltaproteobacteria,2MD0F@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,SPASM
MMS3_k127_3334007_9	445972.ANACOL_00420	5.784e-32	140.0	COG1063@1|root,COG1063@2|Bacteria,1V57T@1239|Firmicutes,24IGM@186801|Clostridia,3WNFU@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3334007_11	879212.DespoDRAFT_03493	1.394e-15	83.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WM56@28221|Deltaproteobacteria,2MHKW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
MMS3_k127_3334007_4	1242864.D187_009928	1.92e-70	251.0	COG3437@1|root,COG3437@2|Bacteria,1RGGM@1224|Proteobacteria,42RTT@68525|delta/epsilon subdivisions,2WNA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
MMS3_k127_3334007_10	1173028.ANKO01000030_gene3274	1.079e-15	91.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1H7H2@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
MMS3_k127_3334007_2	1379698.RBG1_1C00001G1421	2.626e-77	284.0	COG4191@1|root,COG4191@2|Bacteria,2NQ9F@2323|unclassified Bacteria	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS_4,PAS_8,PAS_9,Response_reg
MMS3_k127_3334007_1	909663.KI867150_gene570	5.234e-87	297.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42RGD@68525|delta/epsilon subdivisions,2WP0A@28221|Deltaproteobacteria,2MRRF@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
MMS3_k127_3334007_6	671143.DAMO_1765	5.224e-69	244.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
MMS3_k127_3334007_0	443144.GM21_2151	3.364e-127	444.0	COG2202@1|root,COG2204@1|root,COG3852@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
MMS3_k127_3339565_32	1128421.JAGA01000001_gene2145	2.616e-40	151.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_05735	-	-	-	-	-	-	-	-	-	-	-	HTH_34
MMS3_k127_3339565_24	1304880.JAGB01000002_gene2320	5.655e-68	250.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
MMS3_k127_3339565_0	204669.Acid345_0064	4.488e-262	821.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_3339565_19	404589.Anae109_2337	1.297e-71	252.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
MMS3_k127_3339565_23	204669.Acid345_0278	3.529e-69	244.0	COG1624@1|root,COG1624@2|Bacteria,3Y7NU@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
MMS3_k127_3339565_46	1201288.M900_1544	1.334e-05	57.0	COG4856@1|root,COG4856@2|Bacteria	2|Bacteria	O	YbbR-like protein	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
MMS3_k127_3339565_4	234267.Acid_1911	5.197e-125	415.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_3339565_15	391625.PPSIR1_11450	6.273e-77	271.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
MMS3_k127_3339565_2	234267.Acid_4393	7.522e-177	589.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3339565_37	204669.Acid345_0732	4.186e-26	117.0	COG4235@1|root,COG4235@2|Bacteria,3Y8SD@57723|Acidobacteria	57723|Acidobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3339565_45	690850.Desaf_3031	5.772e-06	51.0	COG3350@1|root,COG3350@2|Bacteria,1NCWJ@1224|Proteobacteria,42WJP@68525|delta/epsilon subdivisions,2WS92@28221|Deltaproteobacteria,2MD2M@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART TRASH domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
MMS3_k127_3339565_26	1191523.MROS_0095	4.418e-66	235.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	fucA	-	2.7.1.189,4.1.2.17,5.1.3.4	ko:K01628,ko:K03077,ko:K11216	ko00040,ko00051,ko00053,ko01100,ko01120,ko02024,map00040,map00051,map00053,map01100,map01120,map02024	M00550	R02262,R05850,R11183	RC00002,RC00017,RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
MMS3_k127_3339565_33	234267.Acid_0321	7.659e-38	145.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
MMS3_k127_3339565_38	234267.Acid_0322	8.81e-25	111.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028,ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
MMS3_k127_3339565_39	1408422.JHYF01000002_gene2330	4.531e-22	98.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,36N12@31979|Clostridiaceae	186801|Clostridia	CQ	Ethanolamine utilization protein EutN carboxysome structural protein Ccml	ccmL	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
MMS3_k127_3339565_43	1410668.JNKC01000003_gene465	7.853e-08	60.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,36N12@31979|Clostridiaceae	186801|Clostridia	CQ	Ethanolamine utilization protein EutN carboxysome structural protein Ccml	ccmL	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
MMS3_k127_3339565_9	1184607.AUCHE_17_01420	4.682e-96	327.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4F6MS@85018|Dermatophilaceae	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_3339565_28	867845.KI911784_gene502	9.801e-58	215.0	COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi,375YQ@32061|Chloroflexia	32061|Chloroflexia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_3339565_34	1201288.M900_0293	5.435e-34	137.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
MMS3_k127_3339565_20	671143.DAMO_0383	6.409e-71	251.0	COG1801@1|root,COG1801@2|Bacteria,2NPDU@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMS3_k127_3339565_42	1111479.AXAR01000001_gene384	4.365e-11	66.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,27AEX@186823|Alicyclobacillaceae	91061|Bacilli	P	ArsC family	yusI	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
MMS3_k127_3339565_13	880073.Calab_2511	1.292e-80	274.0	COG0602@1|root,COG0602@2|Bacteria,2NPEM@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100	-	R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
MMS3_k127_3339565_10	1125863.JAFN01000001_gene2317	6.55e-93	310.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
MMS3_k127_3339565_31	1379270.AUXF01000001_gene2252	1.825e-40	171.0	COG4191@1|root,COG4191@2|Bacteria,1ZUJZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
MMS3_k127_3339565_22	290397.Adeh_4220	3.249e-69	256.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria	1224|Proteobacteria	S	Related to alanyl-tRNA synthetase HxxxH domain	-	-	6.1.1.7	ko:K01872,ko:K07050	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
MMS3_k127_3339565_1	478741.JAFS01000001_gene2075	3.081e-182	580.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Penicillinase_R
MMS3_k127_3339565_17	880073.Calab_3262	4.339e-72	262.0	COG2027@1|root,COG2027@2|Bacteria,2NP5E@2323|unclassified Bacteria	2|Bacteria	M	COGs COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	DUF1460,Peptidase_S13
MMS3_k127_3339565_36	671143.DAMO_0835	1.492e-31	139.0	2DN50@1|root,32VJ4@2|Bacteria,2NQ0E@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
MMS3_k127_3339565_11	1499967.BAYZ01000095_gene4168	4.072e-88	310.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
MMS3_k127_3339565_18	1382359.JIAL01000001_gene1268	8.269e-72	251.0	COG1277@1|root,COG1277@2|Bacteria,3Y6D0@57723|Acidobacteria	57723|Acidobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_3339565_8	234267.Acid_4515	1.351e-104	350.0	COG1131@1|root,COG1131@2|Bacteria,3Y6FZ@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3339565_30	397948.Cmaq_0183	2.12e-43	166.0	COG1225@1|root,arCOG00310@2157|Archaea,2XQPI@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS3_k127_3339565_6	479434.Sthe_1848	1.97e-113	385.0	COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi,27YYU@189775|Thermomicrobia	189775|Thermomicrobia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
MMS3_k127_3339565_47	1121374.KB891592_gene2932	0.0001863	52.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Protoglobin,Response_reg
MMS3_k127_3339565_44	1128421.JAGA01000001_gene2378	5.576e-06	58.0	2DRHT@1|root,33BTG@2|Bacteria,2NRSJ@2323|unclassified Bacteria	2|Bacteria	S	lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
MMS3_k127_3339565_12	1125863.JAFN01000001_gene1414	2.527e-82	283.0	COG1606@1|root,COG1606@2|Bacteria,1R7UZ@1224|Proteobacteria,42Q6V@68525|delta/epsilon subdivisions,2WKIM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM asparagine synthase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
MMS3_k127_3339565_35	330214.NIDE3359	5.361e-33	135.0	COG2885@1|root,COG2885@2|Bacteria,3J17Q@40117|Nitrospirae	2|Bacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
MMS3_k127_3339565_41	216591.BCAL2868	1.585e-11	76.0	COG0695@1|root,COG0695@2|Bacteria,1N82H@1224|Proteobacteria,2VWG7@28216|Betaproteobacteria,1K9F5@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM glutaredoxin 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
MMS3_k127_3339565_27	264732.Moth_0883	3.928e-61	232.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,42G12@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
MMS3_k127_3339565_7	667015.Bacsa_0641	9.931e-106	353.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,2FPMW@200643|Bacteroidia,4AKT8@815|Bacteroidaceae	976|Bacteroidetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMS3_k127_3339565_29	243231.GSU1756	7.295e-48	183.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
MMS3_k127_3339565_25	745776.DGo_CA2068	1.118e-66	235.0	COG2065@1|root,COG2065@2|Bacteria,1WJWR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
MMS3_k127_3339565_5	1121468.AUBR01000026_gene2951	3.631e-120	400.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,42EY2@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMS3_k127_3339565_3	338963.Pcar_1614	1.257e-137	452.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,43TVY@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
MMS3_k127_3339565_40	484770.UFO1_1608	5.381e-14	83.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4H2G4@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
MMS3_k127_3339565_16	671143.DAMO_3042	3.364e-74	260.0	COG0177@1|root,COG0177@2|Bacteria,2NQYE@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF2400)	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF2400,EndIII_4Fe-2S,HhH-GPD
MMS3_k127_3339565_14	1125863.JAFN01000001_gene535	4.535e-78	274.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_3339565_21	247490.KSU1_D0287	9.026e-71	248.0	COG1216@1|root,COG1216@2|Bacteria,2IZV9@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3359765_0	697282.Mettu_3710	0.0	2563.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1XFZN@135618|Methylococcales	135618|Methylococcales	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3359765_6	1088721.NSU_3814	5.118e-27	124.0	COG3251@1|root,COG3251@2|Bacteria,1PIM8@1224|Proteobacteria,2V0GQ@28211|Alphaproteobacteria,2KC7Y@204457|Sphingomonadales	204457|Sphingomonadales	S	MbtH-like protein	-	-	-	ko:K05375	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH
MMS3_k127_3359765_5	1173024.KI912153_gene8	2.207e-105	349.0	COG1250@1|root,COG1250@2|Bacteria,1G1VT@1117|Cyanobacteria	1117|Cyanobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS3_k127_3359765_7	316274.Haur_3969	5.544e-20	102.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
MMS3_k127_3359765_1	402777.KB235898_gene5721	3.388e-132	432.0	COG1960@1|root,COG1960@2|Bacteria,1G3AS@1117|Cyanobacteria,1H8VI@1150|Oscillatoriales	1117|Cyanobacteria	I	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
MMS3_k127_3359765_3	479432.Sros_1195	1.595e-129	427.0	COG3882@1|root,COG3882@2|Bacteria,2GNIM@201174|Actinobacteria,4EFGB@85012|Streptosporangiales	201174|Actinobacteria	Q	HAD-superfamily phosphatase, subfamily IIIC	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3359765_2	1267535.KB906767_gene859	1.289e-129	419.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_3359765_4	859657.RPSI07_mp0139	3.551e-126	414.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2VH1Q@28216|Betaproteobacteria,1K10Z@119060|Burkholderiaceae	28216|Betaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_3370401_6	861299.J421_0282	6.451e-118	411.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_3370401_23	882378.RBRH_02340	1.274e-08	65.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1K0BI@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
MMS3_k127_3370401_5	240015.ACP_1207	4.212e-123	418.0	COG4063@1|root,COG4063@2|Bacteria	2|Bacteria	H	Domain of unknown function (DUF4346)	-	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4346,MtrA
MMS3_k127_3370401_16	1125863.JAFN01000001_gene3426	7.235e-34	134.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_24
MMS3_k127_3370401_9	1296416.JACB01000044_gene4920	5.979e-60	227.0	COG1680@1|root,COG1680@2|Bacteria,4NIG6@976|Bacteroidetes,1I137@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_3370401_4	1415779.JOMH01000001_gene589	3.801e-124	413.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,1T1NH@1236|Gammaproteobacteria,1X37G@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Major facilitator superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
MMS3_k127_3370401_14	290397.Adeh_3771	7.47e-38	158.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWEZ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
MMS3_k127_3370401_0	1267533.KB906736_gene1013	1.572e-294	915.0	COG2936@1|root,COG2936@2|Bacteria,3Y33N@57723|Acidobacteria	57723|Acidobacteria	S	Hydrolase CocE NonD family	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_3370401_3	1267534.KB906755_gene4646	6.582e-154	529.0	COG1228@1|root,COG1228@2|Bacteria,3Y2MZ@57723|Acidobacteria,2JI4B@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_3370401_17	1110697.NCAST_19_00440	1.441e-28	124.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria,4G1GK@85025|Nocardiaceae	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
MMS3_k127_3370401_1	1379270.AUXF01000003_gene3617	4.405e-224	726.0	COG0551@1|root,COG0551@2|Bacteria,1ZUEQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
MMS3_k127_3370401_19	1283284.AZUK01000001_gene870	6.612e-24	113.0	2EFNH@1|root,339EN@2|Bacteria,1NNV3@1224|Proteobacteria,1SINQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3370401_8	1123278.KB893594_gene5871	6.355e-65	226.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47XN3@768503|Cytophagia	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_3370401_2	1123368.AUIS01000019_gene1214	8.032e-203	653.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_3370401_12	28583.AMAG_03115T0	1.733e-49	203.0	COG0438@1|root,KOG2941@2759|Eukaryota,38CDI@33154|Opisthokonta,3NTXV@4751|Fungi	4751|Fungi	O	Glycosyltransferase family 33 protein	ALG1	GO:0000030,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006464,GO:0006486,GO:0006487,GO:0006488,GO:0006490,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0012505,GO:0016740,GO:0016757,GO:0016758,GO:0019187,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.142	ko:K03842	ko00510,ko00513,ko01100,map00510,map00513,map01100	M00055	R05972	-	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT33	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_3370401_20	935557.ATYB01000014_gene2631	2.266e-17	93.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,2U54N@28211|Alphaproteobacteria,4BB7H@82115|Rhizobiaceae	28211|Alphaproteobacteria	MU	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,He_PIG,fn3
MMS3_k127_3370401_10	351160.LRC541	2.085e-59	231.0	COG1287@1|root,arCOG02043@2157|Archaea,2XU8G@28890|Euryarchaeota,2N921@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM Oligosaccharyl transferase STT3 subunit	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
MMS3_k127_3370401_24	298655.KI912266_gene1935	5.148e-06	61.0	COG1216@1|root,COG4123@1|root,COG1216@2|Bacteria,COG4123@2|Bacteria,2GKTW@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
MMS3_k127_3370401_13	634497.HAH_2121	6.324e-45	186.0	COG0438@1|root,arCOG04796@2157|Archaea,2XVMZ@28890|Euryarchaeota,23SUM@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_3370401_25	298655.KI912266_gene1935	3.038e-05	57.0	COG1216@1|root,COG4123@1|root,COG1216@2|Bacteria,COG4123@2|Bacteria,2GKTW@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
MMS3_k127_3370401_18	42099.EPrPV00000020209	2.898e-28	125.0	COG5597@1|root,KOG1950@2759|Eukaryota,1MHK2@121069|Pythiales	121069|Pythiales	G	Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
MMS3_k127_3370401_7	1267535.KB906767_gene5185	1.027e-86	311.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,3Y2P9@57723|Acidobacteria,2JIVP@204432|Acidobacteriia	204432|Acidobacteriia	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
MMS3_k127_3370401_15	395965.Msil_3484	5.24e-36	144.0	COG4113@1|root,COG4113@2|Bacteria,1NEE2@1224|Proteobacteria,2UJ3R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_3370401_21	631362.Thi970DRAFT_02178	6.96e-17	82.0	2A6UU@1|root,30VP8@2|Bacteria,1NQ5B@1224|Proteobacteria,1SUYT@1236|Gammaproteobacteria,1X1Y1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3370401_11	886293.Sinac_4147	3.136e-59	229.0	COG4932@1|root,COG5295@1|root,COG4932@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Glug,Haemagg_act
MMS3_k127_3383249_15	204669.Acid345_1744	8.517e-122	399.0	COG1063@1|root,COG1063@2|Bacteria,3Y30Y@57723|Acidobacteria,2JIRR@204432|Acidobacteriia	204432|Acidobacteriia	E	Zinc-binding dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3383249_16	1340493.JNIF01000003_gene3886	2.156e-121	400.0	COG1063@1|root,COG1063@2|Bacteria,3Y2H8@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3383249_34	395965.Msil_3244	5.912e-10	71.0	COG0775@1|root,COG0775@2|Bacteria,1PETT@1224|Proteobacteria,2TTTB@28211|Alphaproteobacteria,3NB47@45404|Beijerinckiaceae	28211|Alphaproteobacteria	F	Phosphorylase superfamily	MA20_16045	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_3383249_19	671143.DAMO_0002	1.889e-108	368.0	COG0451@1|root,COG0451@2|Bacteria,2NPZU@2323|unclassified Bacteria	2|Bacteria	M	Male sterility protein	dfrA	-	1.1.1.219,5.1.3.26	ko:K00091,ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
MMS3_k127_3383249_6	1303518.CCALI_01615	4.414e-206	660.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
MMS3_k127_3383249_14	204669.Acid345_1739	1.152e-122	401.0	COG0761@1|root,COG0761@2|Bacteria,3Y40M@57723|Acidobacteria,2JIXC@204432|Acidobacteriia	204432|Acidobacteriia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS3_k127_3383249_9	269799.Gmet_2577	3.106e-153	492.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WKF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
MMS3_k127_3383249_0	1121918.ARWE01000001_gene386	0.0	1053.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_3383249_25	1121957.ATVL01000009_gene1051	1.164e-73	257.0	COG0412@1|root,COG0412@2|Bacteria,4NWPN@976|Bacteroidetes,47SED@768503|Cytophagia	976|Bacteroidetes	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
MMS3_k127_3383249_24	314278.NB231_02593	7.13e-86	289.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,1RZBF@1236|Gammaproteobacteria,1X0F6@135613|Chromatiales	135613|Chromatiales	Q	PFAM isochorismatase hydrolase	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
MMS3_k127_3383249_33	1485545.JQLW01000006_gene300	1.349e-13	78.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3383249_2	1121920.AUAU01000012_gene2706	1.481e-313	975.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria	2|Bacteria	C	Dehydrogenase E1 component	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
MMS3_k127_3383249_23	234267.Acid_3611	4.162e-90	307.0	COG1734@1|root,COG2208@1|root,COG1734@2|Bacteria,COG2208@2|Bacteria,3Y4RV@57723|Acidobacteria	57723|Acidobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
MMS3_k127_3383249_17	1095769.CAHF01000006_gene1886	1.337e-117	389.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3383249_26	754476.Q7A_2070	1.934e-71	246.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,460HG@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
MMS3_k127_3383249_30	1280947.HY30_06920	1.752e-37	149.0	COG1309@1|root,COG1309@2|Bacteria,1RJ1R@1224|Proteobacteria,2UBG4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_3383249_21	290397.Adeh_2656	9.057e-94	323.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P6Q@68525|delta/epsilon subdivisions,2WKPS@28221|Deltaproteobacteria,2YXDB@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3383249_3	1173023.KE650771_gene5325	4.981e-242	772.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_3383249_22	1123368.AUIS01000028_gene1325	3.965e-92	334.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
MMS3_k127_3383249_8	379066.GAU_3744	2.253e-187	597.0	COG0513@1|root,COG0513@2|Bacteria,1ZT7G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
MMS3_k127_3383249_27	1123368.AUIS01000019_gene1213	1.033e-65	233.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales	225057|Acidithiobacillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_3383249_1	1340493.JNIF01000004_gene24	1.018e-316	984.0	COG1529@1|root,COG1529@2|Bacteria,3Y77V@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
MMS3_k127_3383249_5	452637.Oter_0021	2.573e-207	673.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_3383249_13	1411123.JQNH01000001_gene3251	7.661e-132	430.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_3383249_12	1192034.CAP_4632	7.731e-134	434.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,42RTY@68525|delta/epsilon subdivisions,2WNFS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
MMS3_k127_3383249_31	941449.dsx2_0702	2.184e-36	150.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	mmyX	-	2.7.4.25,5.3.1.12	ko:K00945,ko:K01812,ko:K16139	ko00040,ko00240,ko01100,map00040,map00240,map01100	M00052,M00061,M00631	R00158,R00512,R01482,R01665,R01983	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.2	-	-	AAA_28,Cytidylate_kin2,MFS_2
MMS3_k127_3383249_7	1192034.CAP_0564	1.306e-197	633.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,42YRA@68525|delta/epsilon subdivisions,2WTWV@28221|Deltaproteobacteria,2YZ7H@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme	-	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
MMS3_k127_3383249_20	926550.CLDAP_20570	2.606e-97	325.0	COG3634@1|root,COG3634@2|Bacteria,2G6SQ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
MMS3_k127_3383249_29	926550.CLDAP_35540	6.997e-38	145.0	COG2363@1|root,COG2363@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF423)	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
MMS3_k127_3383249_28	1267535.KB906767_gene3393	8.324e-63	226.0	2905E@1|root,2ZMVA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
MMS3_k127_3383249_32	521011.Mpal_2554	1.551e-22	107.0	COG0642@1|root,arCOG02350@1|root,arCOG06940@1|root,arCOG02350@2157|Archaea,arCOG06192@2157|Archaea,arCOG06940@2157|Archaea	2157|Archaea	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9
MMS3_k127_3383249_4	1163617.SCD_n01639	3.2e-233	735.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2VIUF@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Pyridoxal-dependent decarboxylase	ddc	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
MMS3_k127_3383249_10	1163617.SCD_n01640	2.704e-139	463.0	COG0189@1|root,COG0189@2|Bacteria,1NNP5@1224|Proteobacteria,2VIF2@28216|Betaproteobacteria	28216|Betaproteobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3383249_18	379066.GAU_3214	1.749e-115	388.0	28J2H@1|root,2Z8YZ@2|Bacteria,1ZUTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3383249_11	1379270.AUXF01000003_gene3619	1.397e-137	460.0	COG0666@1|root,COG0666@2|Bacteria,1ZUQT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3383249_35	243090.RB6572	0.00025	45.0	COG2960@1|root,COG2960@2|Bacteria,2J2F2@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
MMS3_k127_341199_7	1047013.AQSP01000131_gene1841	2.518e-50	205.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_341199_10	929556.Solca_3122	4.324e-15	80.0	2C19F@1|root,32ZRH@2|Bacteria,4NUG5@976|Bacteroidetes,1IYGV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_341199_5	240015.ACP_1984	6.004e-87	300.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
MMS3_k127_341199_0	240015.ACP_1985	0.0	1323.0	COG0841@1|root,COG0841@2|Bacteria,3Y3F4@57723|Acidobacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	swrC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
MMS3_k127_341199_4	240015.ACP_1986	1.676e-125	419.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_341199_2	234267.Acid_7252	7.681e-265	851.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_341199_1	1123278.KB893444_gene1718	0.0	1039.0	COG4447@1|root,COG4447@2|Bacteria,4NK01@976|Bacteroidetes,47NT3@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_341199_6	1340493.JNIF01000003_gene2146	4.376e-58	213.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
MMS3_k127_341199_3	204669.Acid345_1052	2.336e-129	446.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
MMS3_k127_341199_11	1133850.SHJG_1541	5.434e-15	91.0	COG3468@1|root,COG3468@2|Bacteria,2HCJX@201174|Actinobacteria	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
MMS3_k127_341199_8	935845.JADQ01000029_gene1230	2.769e-43	184.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
MMS3_k127_341199_9	886293.Sinac_4147	8.064e-40	173.0	COG4932@1|root,COG5295@1|root,COG4932@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Glug,Haemagg_act
MMS3_k127_3445822_5	1123073.KB899241_gene3024	1.803e-69	252.0	28H8Z@1|root,2ZC05@2|Bacteria,1RBDW@1224|Proteobacteria,1RXUP@1236|Gammaproteobacteria,1X4TV@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1282)	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
MMS3_k127_3445822_13	686340.Metal_2617	1.079e-29	124.0	COG0662@1|root,COG0662@2|Bacteria,1N3N8@1224|Proteobacteria,1SA89@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_3445822_15	639030.JHVA01000001_gene529	1.188e-14	85.0	2AC2T@1|root,311KW@2|Bacteria,3Y4QM@57723|Acidobacteria,2JMHZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3445822_8	330214.NIDE0317	2.805e-48	188.0	COG3663@1|root,COG3663@2|Bacteria	2|Bacteria	L	G/U mismatch-specific uracil-DNA glycosylase activity	mug	GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.28,6.3.3.2	ko:K01934,ko:K03649	ko00670,ko01100,ko03410,map00670,map01100,map03410	-	R02301	RC00183	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_3445822_6	1196323.ALKF01000119_gene5028	2.625e-68	247.0	COG0477@1|root,COG2814@2|Bacteria,1V36U@1239|Firmicutes,4HJX6@91061|Bacilli,26VPJ@186822|Paenibacillaceae	91061|Bacilli	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
MMS3_k127_3445822_0	671143.DAMO_2884	6.683e-296	925.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
MMS3_k127_3445822_2	234267.Acid_6651	2.456e-170	554.0	COG0154@1|root,COG0154@2|Bacteria,3Y3E5@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
MMS3_k127_3445822_7	656024.FsymDg_0185	9.572e-65	225.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4ESIC@85013|Frankiales	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	cypB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
MMS3_k127_3445822_10	1157490.EL26_15170	8.002e-46	174.0	COG0666@1|root,COG0666@2|Bacteria,1V657@1239|Firmicutes,4HIDE@91061|Bacilli	91061|Bacilli	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
MMS3_k127_3445822_9	1121920.AUAU01000016_gene1287	1.759e-47	179.0	COG1633@1|root,COG1633@2|Bacteria,3Y925@57723|Acidobacteria	57723|Acidobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMS3_k127_3445822_3	1121920.AUAU01000016_gene1288	8.462e-142	470.0	COG1013@1|root,COG1013@2|Bacteria,3Y514@57723|Acidobacteria	57723|Acidobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_3445822_1	1121920.AUAU01000016_gene1289	2.041e-228	721.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
MMS3_k127_3445822_12	322710.Avin_15980	3.728e-39	156.0	COG1216@1|root,COG3551@1|root,COG4372@1|root,COG1216@2|Bacteria,COG3551@2|Bacteria,COG4372@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_12,Methyltransf_23
MMS3_k127_3445822_14	1040989.AWZU01000057_gene5091	4.563e-23	102.0	COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria,2UEPY@28211|Alphaproteobacteria,3K08M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3445822_11	1282360.ABAC460_05900	2.957e-39	149.0	COG2350@1|root,COG2350@2|Bacteria,1MZ8Y@1224|Proteobacteria,2UHFW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
MMS3_k127_3445822_4	696747.NIES39_E00230	1.362e-76	262.0	COG0115@1|root,COG0115@2|Bacteria,1G1GM@1117|Cyanobacteria,1H8CZ@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_3463652_3	330214.NIDE0349	2.278e-56	202.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	tesA	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365	Lipase_GDSL_2
MMS3_k127_3463652_2	1382359.JIAL01000001_gene200	6.118e-79	271.0	COG4181@1|root,COG4181@2|Bacteria,3Y3RU@57723|Acidobacteria,2JI42@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3463652_1	330214.NIDE0351	1.406e-119	421.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	MA20_43810	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_3463652_0	1047013.AQSP01000125_gene2615	2.824e-140	461.0	COG2252@1|root,COG2252@2|Bacteria,2NNZ2@2323|unclassified Bacteria	2|Bacteria	S	Permease family	pbuG	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	iECH74115_1262.ECH74115_5145,iECOK1_1307.ECOK1_4117,iECSP_1301.ECSP_4762,iECUMN_1333.ECUMN_4191,iECs_1301.ECs4651,iG2583_1286.G2583_4505,iJO1366.b3714,iUTI89_1310.UTI89_C4220,iY75_1357.Y75_RS18500,iYO844.BSU06370,iZ_1308.Z5209	Xan_ur_permease
MMS3_k127_3463652_4	273068.TTE1572	2.056e-17	87.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,24K3N@186801|Clostridia,42FT9@68295|Thermoanaerobacterales	186801|Clostridia	K	TIGRFAM sporulation protein, yteA	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
MMS3_k127_3463652_5	1121033.AUCF01000017_gene3749	2.273e-14	78.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,2JTRD@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
MMS3_k127_3493061_14	1267533.KB906746_gene35	3.478e-81	283.0	2DP3Z@1|root,2Z8GS@2|Bacteria,3Y390@57723|Acidobacteria,2JIK3@204432|Acidobacteriia	204432|Acidobacteriia	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_3493061_26	13249.RPRC006411-PA	1.558e-15	90.0	COG1345@1|root,2TE2R@2759|Eukaryota,399KQ@33154|Opisthokonta,3CDRJ@33208|Metazoa,3DV3G@33213|Bilateria,42BYY@6656|Arthropoda,3SQJJ@50557|Insecta,3EDUX@33342|Paraneoptera	33208|Metazoa	N	Flagellar hook-associated protein 2 C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	FliD_C
MMS3_k127_3493061_1	1217718.ALOU01000061_gene519	1.728e-222	704.0	COG0591@1|root,COG0591@2|Bacteria,1MWX6@1224|Proteobacteria,2VM1H@28216|Betaproteobacteria,1K154@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
MMS3_k127_3493061_29	1040989.AWZU01000062_gene5469	5.972e-13	70.0	2EGF3@1|root,33A73@2|Bacteria,1N8EG@1224|Proteobacteria,2VGNY@28211|Alphaproteobacteria,3K1N5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
MMS3_k127_3493061_27	1218103.CIN01S_07_01390	2.598e-14	86.0	COG3577@1|root,COG3577@2|Bacteria,4NNJX@976|Bacteroidetes,1I8WP@117743|Flavobacteriia,3ZT3G@59732|Chryseobacterium	976|Bacteroidetes	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
MMS3_k127_3493061_20	1379698.RBG1_1C00001G0743	4.744e-51	188.0	COG2318@1|root,COG2318@2|Bacteria,2NRHG@2323|unclassified Bacteria	2|Bacteria	S	DinB superfamily	dinB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	DinB
MMS3_k127_3493061_34	1245469.S58_48780	2.155e-07	64.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,3JQQI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	MA20_15480	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_3493061_25	1297742.A176_00691	3.284e-17	95.0	COG0025@1|root,COG0025@2|Bacteria,1N7PG@1224|Proteobacteria,42V45@68525|delta/epsilon subdivisions,2WRJ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3493061_15	1297742.A176_00692	3.971e-65	243.0	COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,42RF1@68525|delta/epsilon subdivisions,2WNZ0@28221|Deltaproteobacteria,2YVE9@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Na_H_Exchanger,Usp
MMS3_k127_3493061_10	94624.Bpet3406	1.334e-103	345.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2VJUU@28216|Betaproteobacteria,3T1DF@506|Alcaligenaceae	28216|Betaproteobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
MMS3_k127_3493061_8	1279038.KB907341_gene1895	1.465e-113	376.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,2UAJA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
MMS3_k127_3493061_30	240015.ACP_2093	1.191e-12	70.0	COG1826@1|root,COG1826@2|Bacteria,3Y5GD@57723|Acidobacteria,2JJZP@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_3493061_31	1267535.KB906767_gene1329	5.754e-12	71.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0008150,GO:0040007	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_3493061_4	56780.SYN_01995	5.666e-131	431.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_3493061_13	1192034.CAP_4196	1.202e-81	294.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2YWS4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
MMS3_k127_3493061_17	234267.Acid_7855	8.577e-57	205.0	COG2323@1|root,COG2323@2|Bacteria,3Y4R1@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
MMS3_k127_3493061_3	886293.Sinac_4604	9.631e-157	505.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
MMS3_k127_3493061_6	661478.OP10G_1068	1.667e-125	413.0	COG1446@1|root,COG1446@2|Bacteria	2|Bacteria	E	asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
MMS3_k127_3493061_12	234267.Acid_2317	1.682e-82	285.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
MMS3_k127_3493061_0	330214.NIDE1289	4.27e-246	781.0	COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae	40117|Nitrospirae	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
MMS3_k127_3493061_28	1502852.FG94_04416	3.564e-14	78.0	2DR9X@1|root,33AUW@2|Bacteria,1NKHC@1224|Proteobacteria,2WCWV@28216|Betaproteobacteria,478BV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3493061_19	401053.AciPR4_3532	5.102e-55	218.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3493061_9	234267.Acid_4415	1.481e-113	381.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMS3_k127_3493061_11	1131269.AQVV01000001_gene1364	1.021e-90	318.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
MMS3_k127_3493061_18	525904.Tter_1818	6.166e-56	207.0	28I4Y@1|root,2Z88D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3493061_24	1267535.KB906767_gene3462	6.277e-30	127.0	COG1437@1|root,COG1437@2|Bacteria,3Y4V3@57723|Acidobacteria	57723|Acidobacteria	F	CYTH	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
MMS3_k127_3493061_21	290397.Adeh_3692	2.614e-43	173.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
MMS3_k127_3493061_16	706587.Desti_1483	1.421e-61	228.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2WQ4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	phosphotransferase related to Ser Thr protein kinases	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
MMS3_k127_3493061_23	204669.Acid345_4598	6.195e-32	137.0	COG1082@1|root,COG1082@2|Bacteria,3Y4EN@57723|Acidobacteria,2JJ3U@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_3493061_2	1340493.JNIF01000004_gene335	2.022e-199	629.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria	57723|Acidobacteria	J	PFAM tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
MMS3_k127_3493061_7	278963.ATWD01000001_gene1650	3.342e-122	409.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
MMS3_k127_3493061_22	671143.DAMO_0569	1.559e-32	134.0	COG0779@1|root,COG0779@2|Bacteria,2NPVA@2323|unclassified Bacteria	2|Bacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
MMS3_k127_3493061_5	234267.Acid_5180	2.345e-129	430.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria	57723|Acidobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
MMS3_k127_3493061_36	1035308.AQYY01000001_gene3157	8.558e-05	54.0	COG0481@1|root,COG0532@1|root,COG0481@2|Bacteria,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
MMS3_k127_3501997_6	1125701.HMPREF1221_00764	6.059e-49	180.0	2DPM9@1|root,332MQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3501997_2	383372.Rcas_1792	4.573e-161	519.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi,375RR@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
MMS3_k127_3501997_7	1123508.JH636443_gene4935	3.968e-41	164.0	COG1408@1|root,COG1408@2|Bacteria,2J015@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
MMS3_k127_3501997_5	234267.Acid_6723	1.687e-68	240.0	COG0299@1|root,COG0299@2|Bacteria,3Y49G@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
MMS3_k127_3501997_3	401053.AciPR4_0505	1.005e-127	416.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_3501997_10	368407.Memar_1531	5.773e-06	59.0	COG5635@1|root,arCOG04006@1|root,arCOG02967@2157|Archaea,arCOG04006@2157|Archaea,2Y7N5@28890|Euryarchaeota,2NARR@224756|Methanomicrobia	224756|Methanomicrobia	T	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
MMS3_k127_3501997_1	243231.GSU1636	2.406e-185	591.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
MMS3_k127_3501997_0	1118054.CAGW01000058_gene2063	1.526e-274	863.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,26RX8@186822|Paenibacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_3501997_4	518766.Rmar_2306	1.859e-96	321.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
MMS3_k127_3501997_8	570967.JMLV01000001_gene2909	2.316e-20	93.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,2JTEV@204441|Rhodospirillales	204441|Rhodospirillales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
MMS3_k127_3515490_3	1040989.AWZU01000023_gene4857	6.373e-68	241.0	COG1028@1|root,COG1028@2|Bacteria,1MWIJ@1224|Proteobacteria,2U290@28211|Alphaproteobacteria,3JSB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378	ko:K00059,ko:K18337	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R03942,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10788,R10995,R11671	RC00029,RC00066,RC00117,RC00161	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_3515490_6	204669.Acid345_1405	1.582e-31	142.0	COG0457@1|root,COG0457@2|Bacteria,3Y7Q5@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
MMS3_k127_3515490_4	935840.JAEQ01000023_gene4306	4.326e-59	209.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U7NJ@28211|Alphaproteobacteria,43R40@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_3515490_0	1380394.JADL01000013_gene573	3.108e-174	575.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2JPB3@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
MMS3_k127_3515490_1	196367.JNFG01000016_gene4044	8.92e-123	398.0	COG0500@1|root,COG2226@2|Bacteria,1PECT@1224|Proteobacteria,2VYBR@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_3515490_2	234267.Acid_1737	5.055e-102	364.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_3515490_5	1267533.KB906736_gene1023	4.406e-37	142.0	COG1695@1|root,COG1695@2|Bacteria,3Y7W2@57723|Acidobacteria,2JN2W@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_3523297_2	344747.PM8797T_06150	4.984e-91	315.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3523297_1	1121104.AQXH01000001_gene2187	3.447e-295	941.0	COG4447@1|root,COG4447@2|Bacteria,4NK5F@976|Bacteroidetes,1IWI3@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3523297_3	234267.Acid_7168	4.922e-82	302.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,3Y876@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
MMS3_k127_3523297_13	500153.JOEK01000002_gene416	0.0005175	51.0	COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
MMS3_k127_3523297_0	204669.Acid345_2022	0.0	1095.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria,2JISM@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMS3_k127_3523297_9	370438.PTH_1946	5.925e-47	178.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,24FRV@186801|Clostridia,261K2@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
MMS3_k127_3523297_11	2903.EOD11468	5.634e-14	81.0	COG0666@1|root,KOG0504@2759|Eukaryota	2759|Eukaryota	I	protein ubiquitination	AVO2	GO:0001558,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007154,GO:0007163,GO:0007165,GO:0008150,GO:0009987,GO:0016043,GO:0023052,GO:0030029,GO:0030036,GO:0030950,GO:0030952,GO:0031505,GO:0031929,GO:0031932,GO:0032991,GO:0035556,GO:0038201,GO:0040008,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051716,GO:0065007,GO:0071554,GO:0071555,GO:0071840,GO:0071852	-	ko:K06867,ko:K10335	-	-	-	-	ko00000,ko04121	-	-	-	Ank,Ank_2,Ank_3,Ank_4
MMS3_k127_3523297_5	1035308.AQYY01000001_gene1244	2.348e-65	231.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,261N5@186807|Peptococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	mprA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_3523297_4	234267.Acid_5478	5.488e-66	249.0	COG0642@1|root,COG2205@2|Bacteria,3Y8HM@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMS3_k127_3523297_10	1121405.dsmv_3249	2.956e-24	106.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2MKG1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_3523297_6	234267.Acid_3676	1e-63	225.0	COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria	57723|Acidobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
MMS3_k127_3523297_8	264732.Moth_1489	2.287e-53	200.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,249R4@186801|Clostridia,42FJA@68295|Thermoanaerobacterales	186801|Clostridia	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
MMS3_k127_3523297_7	234267.Acid_5441	9.214e-59	220.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_3532007_3	497964.CfE428DRAFT_6454	3.882e-96	330.0	COG2520@1|root,COG2520@2|Bacteria,46SXB@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
MMS3_k127_3532007_1	251221.35211765	2.834e-187	613.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_3532007_0	251221.35211983	4.099e-196	639.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_3532007_2	419610.Mext_0777	4.749e-121	403.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria,1JXGU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_3532007_4	316067.Geob_1141	1.702e-08	63.0	COG3420@1|root,COG3420@2|Bacteria,1P2RP@1224|Proteobacteria,431DH@68525|delta/epsilon subdivisions,2WWUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
MMS3_k127_3533662_11	234267.Acid_7871	3.397e-111	380.0	COG0616@1|root,COG0616@2|Bacteria,3Y3M1@57723|Acidobacteria	57723|Acidobacteria	OU	PFAM peptidase S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
MMS3_k127_3533662_21	234267.Acid_1856	6.569e-77	279.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y45M@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,SpoIIE
MMS3_k127_3533662_48	1385521.N803_14150	9.58e-05	51.0	COG0343@1|root,COG1598@1|root,COG0343@2|Bacteria,COG1598@2|Bacteria,2IQDG@201174|Actinobacteria	201174|Actinobacteria	J	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3533662_20	1382359.JIAL01000001_gene2437	2.748e-79	289.0	COG0760@1|root,COG0760@2|Bacteria,3Y3BW@57723|Acidobacteria,2JIP1@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
MMS3_k127_3533662_30	1125863.JAFN01000001_gene3329	1.849e-48	189.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
MMS3_k127_3533662_2	234267.Acid_3811	4.784e-174	553.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria	57723|Acidobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS3_k127_3533662_33	1125863.JAFN01000001_gene2975	4.99e-33	140.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
MMS3_k127_3533662_42	278963.ATWD01000001_gene2124	1.43e-07	62.0	2CM1I@1|root,32SDF@2|Bacteria,3Y571@57723|Acidobacteria,2JJRW@204432|Acidobacteriia	204432|Acidobacteriia	S	shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
MMS3_k127_3533662_6	1382359.JIAL01000001_gene1432	1.193e-129	437.0	COG0768@1|root,COG0768@2|Bacteria,3Y3MX@57723|Acidobacteria,2JHRD@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMS3_k127_3533662_19	204669.Acid345_1466	8.466e-82	285.0	COG0772@1|root,COG0772@2|Bacteria,3Y3DZ@57723|Acidobacteria,2JINX@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
MMS3_k127_3533662_3	1499967.BAYZ01000029_gene1223	5.021e-157	515.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
MMS3_k127_3533662_34	861299.J421_4377	7.214e-33	142.0	COG3595@1|root,COG3595@2|Bacteria,1ZU53@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
MMS3_k127_3533662_43	643562.Daes_0536	2.407e-07	61.0	2DRKB@1|root,33C5H@2|Bacteria,1PDKB@1224|Proteobacteria,43989@68525|delta/epsilon subdivisions,2X4FD@28221|Deltaproteobacteria,2MFP6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMS3_k127_3533662_31	204669.Acid345_2486	8.225e-38	148.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3533662_37	477974.Daud_1532	2.989e-18	89.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,262N2@186807|Peptococcaceae	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
MMS3_k127_3533662_25	1536769.P40081_19340	3.487e-61	232.0	COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,26R4P@186822|Paenibacillaceae	91061|Bacilli	E	Thermolysin metallopeptidase, alpha-helical domain	nprB	GO:0005575,GO:0005576	3.4.24.28	ko:K01400,ko:K08777	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
MMS3_k127_3533662_27	443143.GM18_3375	1.143e-57	222.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PHB@68525|delta/epsilon subdivisions,2WMJX@28221|Deltaproteobacteria,43S0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,KOW
MMS3_k127_3533662_46	1125863.JAFN01000001_gene3054	2.615e-05	57.0	COG1413@1|root,COG1413@2|Bacteria,1NR1B@1224|Proteobacteria	1224|Proteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
MMS3_k127_3533662_24	443143.GM18_3375	1.613e-65	241.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PHB@68525|delta/epsilon subdivisions,2WMJX@28221|Deltaproteobacteria,43S0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,KOW
MMS3_k127_3533662_49	316067.Geob_3704	0.0002917	54.0	COG1413@1|root,COG1413@2|Bacteria,1NR1B@1224|Proteobacteria,42YUS@68525|delta/epsilon subdivisions,2WUMI@28221|Deltaproteobacteria,43TSX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
MMS3_k127_3533662_4	1267533.KB906733_gene3009	1.079e-138	457.0	COG1972@1|root,COG1972@2|Bacteria,3Y2KI@57723|Acidobacteria,2JIKE@204432|Acidobacteriia	204432|Acidobacteriia	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
MMS3_k127_3533662_18	1430331.EP10_18360	7.232e-87	302.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_3533662_8	401053.AciPR4_1768	4.034e-122	401.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria,2JHZX@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
MMS3_k127_3533662_15	290397.Adeh_3687	8.587e-94	323.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2YTSN@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
MMS3_k127_3533662_32	204669.Acid345_1350	5.356e-35	145.0	COG1051@1|root,COG1051@2|Bacteria,3Y5BM@57723|Acidobacteria,2JJTC@204432|Acidobacteriia	204432|Acidobacteriia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_3533662_26	1379698.RBG1_1C00001G0930	8.121e-59	207.0	COG0432@1|root,COG0432@2|Bacteria,2NPB7@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
MMS3_k127_3533662_0	234267.Acid_1245	1.72e-205	653.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMS3_k127_3533662_23	562970.Btus_2586	1.057e-66	238.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,4HTP0@91061|Bacilli,279M4@186823|Alicyclobacillaceae	91061|Bacilli	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMS3_k127_3533662_16	1210884.HG799462_gene8049	1.074e-92	315.0	COG1131@1|root,COG1131@2|Bacteria,2IZ5V@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3533662_35	1047013.AQSP01000128_gene415	7.314e-31	133.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
MMS3_k127_3533662_14	1210884.HG799462_gene8051	3.317e-95	333.0	COG1131@1|root,COG1131@2|Bacteria,2IZF2@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_3533662_36	1047013.AQSP01000128_gene413	2.539e-27	128.0	2DU2Y@1|root,33NQT@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
MMS3_k127_3533662_40	1267535.KB906767_gene5309	7.026e-10	70.0	2FA03@1|root,34298@2|Bacteria,3Y84H@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3533662_38	1297865.APJD01000009_gene2761	3.548e-16	86.0	COG2105@1|root,COG2105@2|Bacteria,1N80E@1224|Proteobacteria,2U5YU@28211|Alphaproteobacteria,3JY9V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
MMS3_k127_3533662_13	234267.Acid_7676	3.551e-97	336.0	COG2234@1|root,COG2234@2|Bacteria,3Y43U@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_3533662_45	56110.Oscil6304_3947	1.91e-05	54.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1FZXP@1117|Cyanobacteria,1H9CI@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
MMS3_k127_3533662_29	316274.Haur_4259	6.583e-52	207.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
MMS3_k127_3533662_44	1501230.ET33_14615	1.932e-06	62.0	COG0419@1|root,COG1196@1|root,COG3027@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,26QBQ@186822|Paenibacillaceae	91061|Bacilli	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
MMS3_k127_3533662_39	262724.TT_C1407	2.715e-15	89.0	COG1470@1|root,COG3895@1|root,COG1470@2|Bacteria,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
MMS3_k127_3533662_7	1382304.JNIL01000001_gene2362	1.66e-123	407.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,2784A@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_3533662_9	448385.sce8151	3.161e-118	390.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS3_k127_3533662_5	997346.HMPREF9374_0789	6.605e-136	443.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,27BB2@186824|Thermoactinomycetaceae	91061|Bacilli	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_3533662_10	316274.Haur_1203	2.704e-117	384.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS3_k127_3533662_22	330214.NIDE3555	1.838e-73	270.0	COG0302@1|root,COG0302@2|Bacteria,3J0Q0@40117|Nitrospirae	40117|Nitrospirae	F	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
MMS3_k127_3533662_12	1123487.KB892835_gene3378	2.126e-107	362.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,2VM0X@28216|Betaproteobacteria,2KZVH@206389|Rhodocyclales	206389|Rhodocyclales	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
MMS3_k127_3533662_28	234267.Acid_5496	2.688e-54	195.0	2C7E0@1|root,330TX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3533662_17	1047013.AQSP01000106_gene1763	1.008e-90	333.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_3533662_1	240015.ACP_0512	4.432e-183	593.0	COG0308@1|root,COG0308@2|Bacteria,3Y3ZS@57723|Acidobacteria,2JK79@204432|Acidobacteriia	204432|Acidobacteriia	E	Phospholipase B	-	-	-	-	-	-	-	-	-	-	-	-	Phospholip_B
MMS3_k127_361339_23	1340493.JNIF01000003_gene4475	0.0003029	50.0	COG2318@1|root,COG2318@2|Bacteria,3Y8H7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
MMS3_k127_361339_20	345341.KUTG_05034	2.263e-16	87.0	COG0454@1|root,COG0456@2|Bacteria,2II52@201174|Actinobacteria,4E3TJ@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_361339_1	338966.Ppro_2835	2.83e-231	746.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43TIJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
MMS3_k127_361339_12	243231.GSU3250	3.838e-75	271.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,43TZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
MMS3_k127_361339_17	1121877.JQKF01000007_gene981	2.605e-59	213.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
MMS3_k127_361339_8	1120985.AUMI01000011_gene435	2.281e-137	446.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4H26T@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
MMS3_k127_361339_7	234267.Acid_3960	7.927e-142	460.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_361339_9	452637.Oter_3628	7.857e-121	401.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,3K7UU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
MMS3_k127_361339_13	1379281.AVAG01000050_gene936	1.913e-72	262.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMS3_k127_361339_2	404589.Anae109_0318	2.095e-174	562.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2YVA7@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
MMS3_k127_361339_10	234267.Acid_5283	1.618e-116	387.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
MMS3_k127_361339_11	861299.J421_0779	1.068e-106	373.0	COG0652@1|root,COG0652@2|Bacteria,1ZTYX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
MMS3_k127_361339_0	886293.Sinac_4683	7.688e-300	933.0	COG0457@1|root,COG0457@2|Bacteria	886293.Sinac_4683|-	S	peptidyl-tyrosine sulfation	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
MMS3_k127_361339_5	402626.Rpic_4381	6.701e-150	488.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,1K32K@119060|Burkholderiaceae	28216|Betaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
MMS3_k127_361339_14	861299.J421_0324	7.305e-72	258.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_361339_16	1227499.C493_21027	2.217e-64	230.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XVM6@28890|Euryarchaeota,23UEW@183963|Halobacteria	183963|Halobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_361339_19	1122143.AUEG01000001_gene499	3.897e-31	138.0	2B4YW@1|root,31XRX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_361339_22	351016.RAZWK3B_14509	2.385e-06	59.0	COG3409@1|root,COG3409@2|Bacteria,1QVVX@1224|Proteobacteria,2UMGA@28211|Alphaproteobacteria,2P4DI@2433|Roseobacter	28211|Alphaproteobacteria	M	Type VI secretion system VasI, EvfG, VC_A0118	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
MMS3_k127_361339_15	526227.Mesil_1866	3.246e-65	238.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMS3_k127_361339_6	1163408.UU9_16061	9.801e-148	495.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1X3DB@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
MMS3_k127_361339_3	438753.AZC_4378	1.883e-162	519.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,3F1HK@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_361339_4	479434.Sthe_2347	5.174e-158	518.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	189775|Thermomicrobia	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_361339_18	1157708.KB907452_gene3686	2.813e-56	205.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2VK5Y@28216|Betaproteobacteria,4AAXY@80864|Comamonadaceae	28216|Betaproteobacteria	O	SMART Prolyl 4-hydroxylase, alpha subunit	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
MMS3_k127_361339_21	521674.Plim_1577	3.906e-16	80.0	COG1028@1|root,COG1028@2|Bacteria,2IXK3@203682|Planctomycetes	203682|Planctomycetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
MMS3_k127_3630600_11	697282.Mettu_3700	2.631e-15	85.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt
MMS3_k127_3630600_0	1144275.COCOR_04204	0.0	1873.0	COG0318@1|root,COG1020@1|root,COG3321@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,COG3321@2|Bacteria,1MU6G@1224|Proteobacteria,43C6Z@68525|delta/epsilon subdivisions,2X8MX@28221|Deltaproteobacteria,2YYNS@29|Myxococcales	68525|delta/epsilon subdivisions	IQ	Luciferase-like monooxygenase	-	-	-	ko:K18660	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Bac_luciferase,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
MMS3_k127_3630600_1	68219.JNXI01000002_gene4101	0.0	1465.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
MMS3_k127_3630600_7	1380394.JADL01000002_gene1597	2.219e-55	201.0	COG0053@1|root,COG0053@2|Bacteria,1ND3V@1224|Proteobacteria,2U3WH@28211|Alphaproteobacteria,2JWFJ@204441|Rhodospirillales	204441|Rhodospirillales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
MMS3_k127_3630600_3	240015.ACP_2414	1.687e-157	507.0	COG1226@1|root,COG1226@2|Bacteria,3Y4K4@57723|Acidobacteria,2JMIM@204432|Acidobacteriia	204432|Acidobacteriia	P	TrkA-C domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
MMS3_k127_3630600_12	1123371.ATXH01000004_gene1743	4.521e-05	54.0	COG1406@1|root,COG1406@2|Bacteria,2GHVU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
MMS3_k127_3630600_8	1379858.N508_00986	5.879e-35	144.0	COG2199@1|root,COG3706@2|Bacteria,2GFGI@200930|Deferribacteres	200930|Deferribacteres	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
MMS3_k127_3630600_4	861299.J421_4428	5.811e-119	398.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS3_k127_3630600_5	1123277.KB893187_gene2694	1.126e-96	332.0	COG2124@1|root,COG2124@2|Bacteria,4NG9Z@976|Bacteroidetes,47KN0@768503|Cytophagia	976|Bacteroidetes	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450
MMS3_k127_3630600_6	2074.JNYD01000001_gene6087	7.92e-81	304.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4DZ0E@85010|Pseudonocardiales	201174|Actinobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
MMS3_k127_3630600_9	931627.MycrhDRAFT_5227	4.526e-32	142.0	28M2T@1|root,2ZAH6@2|Bacteria,2H696@201174|Actinobacteria,237M6@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3630600_2	1123277.KB893187_gene2689	2.488e-252	800.0	COG0142@1|root,COG5621@1|root,COG0142@2|Bacteria,COG5621@2|Bacteria,4NKGY@976|Bacteroidetes	976|Bacteroidetes	H	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9,polyprenyl_synt
MMS3_k127_3630600_10	411684.HPDFL43_17496	2.57e-19	89.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2TS2G@28211|Alphaproteobacteria,43M00@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
MMS3_k127_3637061_1	1232410.KI421412_gene357	1.282e-106	361.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,43TDI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
MMS3_k127_3637061_3	926550.CLDAP_09840	9.093e-49	183.0	COG0633@1|root,COG0633@2|Bacteria	2|Bacteria	C	Ferredoxin	fdx5	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
MMS3_k127_3637061_0	580332.Slit_1414	3.623e-156	503.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,44VKE@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
MMS3_k127_3637061_5	234267.Acid_5527	1.266e-43	163.0	COG2967@1|root,COG2967@2|Bacteria	2|Bacteria	P	mitochondrion morphogenesis	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
MMS3_k127_3637061_7	886293.Sinac_3496	4.114e-08	58.0	2DTD4@1|root,33JTG@2|Bacteria,2J4JM@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3637061_2	644966.Tmar_1774	6.397e-68	258.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WCUH@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
MMS3_k127_3637061_4	1437425.CSEC_2420	2.403e-47	173.0	COG3411@1|root,COG3411@2|Bacteria,2JH6P@204428|Chlamydiae	204428|Chlamydiae	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3637061_6	1250232.JQNJ01000001_gene3391	8.801e-10	60.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1HXHX@117743|Flavobacteriia	976|Bacteroidetes	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
MMS3_k127_3637064_27	1267535.KB906767_gene352	7.306e-45	165.0	COG1695@1|root,COG1695@2|Bacteria,3Y5CW@57723|Acidobacteria,2JJPQ@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_3637064_30	1047013.AQSP01000114_gene700	4.399e-40	151.0	COG3093@1|root,COG3093@2|Bacteria,2NR60@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
MMS3_k127_3637064_32	1123024.AUII01000004_gene1505	4.027e-34	133.0	COG3549@1|root,COG3549@2|Bacteria,2IT6K@201174|Actinobacteria	201174|Actinobacteria	S	Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
MMS3_k127_3637064_9	1267534.KB906761_gene1200	4.282e-162	542.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_3637064_13	1267535.KB906767_gene5108	4.74e-137	469.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria,2JITF@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_3637064_29	1267535.KB906767_gene5109	3.248e-42	157.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_3637064_47	1407650.BAUB01000024_gene2730	5.234e-11	69.0	COG0515@1|root,COG0515@2|Bacteria,1GH8T@1117|Cyanobacteria,1H3SE@1129|Synechococcus	1117|Cyanobacteria	KLT	Domain of unknown function (DUF4189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4189
MMS3_k127_3637064_10	1173263.Syn7502_01604	1.999e-158	507.0	COG2345@1|root,COG2345@2|Bacteria,1GQGN@1117|Cyanobacteria,1H40G@1129|Synechococcus	1117|Cyanobacteria	H	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
MMS3_k127_3637064_6	742738.HMPREF9460_01412	2.566e-184	593.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,267QX@186813|unclassified Clostridiales	186801|Clostridia	F	Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
MMS3_k127_3637064_16	1107311.Q767_03030	7.437e-117	391.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1HWSK@117743|Flavobacteriia,2NUEG@237|Flavobacterium	976|Bacteroidetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
MMS3_k127_3637064_43	1397278.AYMV01000029_gene384	1.594e-16	84.0	COG1725@1|root,COG1725@2|Bacteria,2IHTD@201174|Actinobacteria,4FQ3H@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
MMS3_k127_3637064_39	1382304.JNIL01000001_gene1872	1.981e-21	107.0	COG4194@1|root,COG4194@2|Bacteria,1UY2R@1239|Firmicutes,4HEEQ@91061|Bacilli	91061|Bacilli	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
MMS3_k127_3637064_8	234267.Acid_0103	2.32e-165	537.0	COG0477@1|root,COG2814@2|Bacteria,3Y2YV@57723|Acidobacteria	57723|Acidobacteria	EGP	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
MMS3_k127_3637064_4	1267535.KB906767_gene4612	1.206e-216	698.0	COG0577@1|root,COG0577@2|Bacteria	1267535.KB906767_gene4612|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3637064_52	387631.Asulf_01034	0.0006535	49.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,24607@183980|Archaeoglobi	183980|Archaeoglobi	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
MMS3_k127_3637064_15	1158292.JPOE01000002_gene1873	2.954e-126	417.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,1KJCP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
MMS3_k127_3637064_1	1158292.JPOE01000002_gene1874	3.939e-286	894.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VHZ2@28216|Betaproteobacteria,1KPMQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
MMS3_k127_3637064_5	861299.J421_3809	3.279e-208	679.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
MMS3_k127_3637064_36	1382359.JIAL01000001_gene2134	5.803e-30	123.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
MMS3_k127_3637064_28	886293.Sinac_6279	1.658e-42	158.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
MMS3_k127_3637064_25	861299.J421_1461	2.755e-50	202.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
MMS3_k127_3637064_45	1162668.LFE_1777	1.759e-13	73.0	COG0762@1|root,COG0762@2|Bacteria,3J0U5@40117|Nitrospirae	40117|Nitrospirae	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
MMS3_k127_3637064_51	861299.J421_3910	7.761e-07	62.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMS3_k127_3637064_34	379066.GAU_2442	1.874e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3637064_46	1123278.KB893555_gene4013	2.728e-12	78.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47KTR@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
MMS3_k127_3637064_14	1144319.PMI16_04540	7.222e-127	425.0	COG2843@1|root,COG2843@2|Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
MMS3_k127_3637064_7	404589.Anae109_2424	1.663e-167	547.0	COG0249@1|root,COG0249@2|Bacteria,1N9K4@1224|Proteobacteria,42ZN5@68525|delta/epsilon subdivisions,2WUW7@28221|Deltaproteobacteria,2YTSE@29|Myxococcales	28221|Deltaproteobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
MMS3_k127_3637064_20	1128421.JAGA01000003_gene3248	7.948e-92	315.0	COG0477@1|root,COG2814@2|Bacteria,2NQ08@2323|unclassified Bacteria	2|Bacteria	EGP	MFS_1 like family	-	-	-	ko:K08151,ko:K08153	-	M00668,M00717	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
MMS3_k127_3637064_19	1210908.HSB1_15840	9.202e-99	336.0	COG0477@1|root,arCOG00130@2157|Archaea,2XT8X@28890|Euryarchaeota,23TJU@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3637064_26	1267535.KB906767_gene3861	1.516e-48	181.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
MMS3_k127_3637064_21	204669.Acid345_0447	8.056e-90	314.0	COG1538@1|root,COG1538@2|Bacteria,3Y4VV@57723|Acidobacteria,2JJGT@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
MMS3_k127_3637064_17	204669.Acid345_0448	7.159e-116	385.0	COG0845@1|root,COG0845@2|Bacteria,3Y47H@57723|Acidobacteria,2JI8J@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
MMS3_k127_3637064_0	204669.Acid345_0449	0.0	1484.0	COG3696@1|root,COG3696@2|Bacteria,3Y2U0@57723|Acidobacteria,2JIUX@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
MMS3_k127_3637064_42	240016.ABIZ01000001_gene2350	1.271e-17	89.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMS3_k127_3637064_49	123214.PERMA_1300	1.342e-07	63.0	COG3137@1|root,COG3137@2|Bacteria,2G4AG@200783|Aquificae	200783|Aquificae	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
MMS3_k127_3637064_35	867903.ThesuDRAFT_00732	2.992e-30	129.0	COG1309@1|root,COG1309@2|Bacteria,1V3QD@1239|Firmicutes,24TIW@186801|Clostridia	186801|Clostridia	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
MMS3_k127_3637064_24	1382306.JNIM01000001_gene1022	3.018e-58	218.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_3637064_2	1382306.JNIM01000001_gene1023	1.492e-282	890.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_3637064_22	1382306.JNIM01000001_gene1024	3.315e-86	319.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMS3_k127_3637064_37	1232410.KI421421_gene3814	4.063e-29	119.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,43SN3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ATP-dependent Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
MMS3_k127_3637064_3	178901.AmDm5_1652	1.166e-243	774.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,2JPMS@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS3_k127_3637064_33	102125.Xen7305DRAFT_00051540	6.357e-34	142.0	COG0491@1|root,COG0491@2|Bacteria,1GNN3@1117|Cyanobacteria,3VNCV@52604|Pleurocapsales	1117|Cyanobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_3637064_31	204669.Acid345_1477	7.959e-37	151.0	COG0583@1|root,COG0583@2|Bacteria,3Y4EH@57723|Acidobacteria,2JJ60@204432|Acidobacteriia	204432|Acidobacteriia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMS3_k127_3637064_11	861299.J421_0708	2.105e-149	486.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08178	-	-	-	-	ko00000,ko02000	2.A.1.12	-	-	MFS_1,Sugar_tr
MMS3_k127_3637064_12	331869.BAL199_18253	1.62e-145	488.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TTAY@28211|Alphaproteobacteria,4BPEH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMS3_k127_3637064_41	1090318.ATTI01000001_gene2608	1.028e-17	100.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2K0C4@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
MMS3_k127_3637064_23	1408473.JHXO01000009_gene3423	4.011e-74	273.0	COG4775@1|root,COG4775@2|Bacteria,4NR0H@976|Bacteroidetes,2FW6I@200643|Bacteroidia	976|Bacteroidetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
MMS3_k127_3637064_40	1123393.KB891331_gene2951	1.95e-20	106.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RKGT@1224|Proteobacteria,2W99B@28216|Betaproteobacteria,1KSUY@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA
MMS3_k127_3637064_44	757424.Hsero_0554	1.601e-14	78.0	COG3729@1|root,COG3729@2|Bacteria,1NH1J@1224|Proteobacteria,2VY5U@28216|Betaproteobacteria,4754J@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Stress-induced bacterial acidophilic repeat motif	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
MMS3_k127_3637064_38	404589.Anae109_1443	3.218e-27	114.0	COG2924@1|root,COG2924@2|Bacteria,1Q2JG@1224|Proteobacteria,433U0@68525|delta/epsilon subdivisions,2X9ZA@28221|Deltaproteobacteria,2YVYI@29|Myxococcales	28221|Deltaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
MMS3_k127_3637064_18	1267535.KB906767_gene75	1.329e-110	375.0	COG1181@1|root,COG1181@2|Bacteria,3Y7GI@57723|Acidobacteria	57723|Acidobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
MMS3_k127_3637064_48	1267535.KB906767_gene1569	6.399e-10	61.0	COG2234@1|root,COG2234@2|Bacteria,3Y435@57723|Acidobacteria	57723|Acidobacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
MMS3_k127_3648268_26	945713.IALB_0196	2.242e-32	131.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,Haem_bd,PSD1
MMS3_k127_3648268_20	1267535.KB906767_gene237	3.061e-52	191.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_3648268_21	671143.DAMO_2282	1.073e-51	191.0	COG3189@1|root,COG3189@2|Bacteria	2|Bacteria	K	MarR family transcriptional regulator	yeaO	-	-	-	-	-	-	-	-	-	-	-	DUF488
MMS3_k127_3648268_23	82996.sch_10390	1.297e-45	183.0	COG0388@1|root,COG0388@2|Bacteria,1RKC7@1224|Proteobacteria,1S4EA@1236|Gammaproteobacteria,403JS@613|Serratia	1236|Gammaproteobacteria	H	Carbon-nitrogen hydrolase	-	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
MMS3_k127_3648268_30	1120949.KB903315_gene148	1.875e-28	118.0	COG1695@1|root,COG1695@2|Bacteria,2GRVH@201174|Actinobacteria,4DJQ9@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_3648268_35	1449353.JQMQ01000005_gene4837	3.844e-06	56.0	2AYAU@1|root,31QDE@2|Bacteria,2H2PB@201174|Actinobacteria,2NKY5@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3648268_18	1227739.Hsw_0739	2.339e-67	250.0	COG0249@1|root,COG0249@2|Bacteria,4NGEA@976|Bacteroidetes,47NI1@768503|Cytophagia	976|Bacteroidetes	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V
MMS3_k127_3648268_22	521011.Mpal_0166	1.308e-46	187.0	arCOG08211@1|root,arCOG08211@2157|Archaea,2XW85@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3648268_13	136273.GY22_06920	1.067e-77	269.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,1W9FM@1268|Micrococcaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS3_k127_3648268_6	1121377.KB906402_gene3276	2.916e-161	529.0	COG0624@1|root,COG0624@2|Bacteria,1WMF4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3648268_15	1121377.KB906432_gene905	5.161e-72	256.0	COG3608@1|root,COG3608@2|Bacteria	2|Bacteria	G	succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
MMS3_k127_3648268_10	1121380.JNIW01000013_gene2001	1.048e-109	361.0	COG1028@1|root,COG1028@2|Bacteria,1WJEE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_3648268_9	926554.KI912670_gene2030	7.64e-114	377.0	COG1893@1|root,COG1893@2|Bacteria	2|Bacteria	H	2-dehydropantoate 2-reductase activity	-	-	1.1.1.169,3.4.17.11	ko:K00077,ko:K01295	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	ApbA,ApbA_C,M20_dimer,Peptidase_M20
MMS3_k127_3648268_11	1040982.AXAL01000031_gene642	5.749e-100	330.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2TTHV@28211|Alphaproteobacteria,43P13@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_3648268_8	1121920.AUAU01000007_gene506	1.799e-129	427.0	COG0477@1|root,COG2814@2|Bacteria,3Y6YQ@57723|Acidobacteria	57723|Acidobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3648268_7	671143.DAMO_2996	1.853e-153	516.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_3648268_24	697282.Mettu_1755	2.092e-43	160.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,1SAWR@1236|Gammaproteobacteria,1XFGD@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
MMS3_k127_3648268_33	880073.Calab_1588	2.146e-10	72.0	COG0535@1|root,COG0535@2|Bacteria,2NPMF@2323|unclassified Bacteria	2|Bacteria	Q	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
MMS3_k127_3648268_19	395961.Cyan7425_4152	1.754e-64	227.0	2CMKX@1|root,32SF3@2|Bacteria	2|Bacteria	S	Protein of unknown function with HXXEE motif	-	-	-	-	-	-	-	-	-	-	-	-	HXXEE
MMS3_k127_3648268_28	760192.Halhy_4503	4.036e-31	130.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
MMS3_k127_3648268_0	1408473.JHXO01000005_gene1588	4.559e-315	980.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,2FRU7@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
MMS3_k127_3648268_31	463191.SSEG_03503	9.252e-20	99.0	2C19F@1|root,32TZS@2|Bacteria,2IQN6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3648268_14	215803.DB30_0292	4.434e-73	250.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_3648268_17	290397.Adeh_2142	1.031e-70	243.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2WPQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EJ	PFAM Asparaginase	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
MMS3_k127_3648268_5	379066.GAU_3201	1.146e-171	563.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1ZURW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
MMS3_k127_3648268_16	379066.GAU_3202	7.894e-71	259.0	COG1126@1|root,COG1126@2|Bacteria,1ZVAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
MMS3_k127_3648268_36	1382306.JNIM01000001_gene482	4.647e-05	53.0	COG0457@1|root,COG0457@2|Bacteria	1382306.JNIM01000001_gene482|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3648268_4	1340493.JNIF01000003_gene1819	1.834e-190	666.0	COG2911@1|root,COG4775@1|root,COG2911@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,Bac_surface_Ag,DUF748,POTRA,TamB
MMS3_k127_3648268_2	243090.RB3466	3.654e-279	871.0	COG0187@1|root,COG0187@2|Bacteria,2IWXP@203682|Planctomycetes	203682|Planctomycetes	L	COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	-	-	5.99.1.3	ko:K02470,ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMS3_k127_3648268_29	1267533.KB906739_gene2780	2.167e-29	122.0	COG2259@1|root,COG2259@2|Bacteria,3Y5JF@57723|Acidobacteria,2JMUV@204432|Acidobacteriia	204432|Acidobacteriia	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3648268_12	234267.Acid_7883	1.718e-90	317.0	COG1432@1|root,COG1432@2|Bacteria,3Y64C@57723|Acidobacteria	57723|Acidobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
MMS3_k127_3648268_3	378806.STAUR_3151	6.202e-276	870.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,42YR5@68525|delta/epsilon subdivisions,2WUG0@28221|Deltaproteobacteria,2YU2X@29|Myxococcales	28221|Deltaproteobacteria	L	topoisomerase	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMS3_k127_3648268_1	886293.Sinac_4895	1.639e-294	921.0	COG3968@1|root,COG3968@2|Bacteria,2IXF6@203682|Planctomycetes	203682|Planctomycetes	S	Glutamine synthetase type III	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
MMS3_k127_3648268_25	518766.Rmar_0985	1.83e-41	162.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1FJB8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_3648268_32	1231391.AMZF01000001_gene2866	1.271e-10	64.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria	1224|Proteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS3_k127_3648268_27	1121937.AUHJ01000001_gene511	3.373e-32	128.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,1S4K1@1236|Gammaproteobacteria,46AJ1@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
MMS3_k127_3648268_34	1397528.Q671_05700	1.047e-08	64.0	COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,1XHM4@135619|Oceanospirillales	135619|Oceanospirillales	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
MMS3_k127_3657564_12	1336245.JAGO01000015_gene2056	1.106e-17	83.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,1XNGA@135619|Oceanospirillales	135619|Oceanospirillales	G	Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
MMS3_k127_3657564_3	1123073.KB899242_gene1561	3.787e-107	356.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1X36V@135614|Xanthomonadales	135614|Xanthomonadales	G	fructokinase	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_3657564_0	1118235.CAJH01000009_gene586	3.711e-208	668.0	COG2942@1|root,COG2942@2|Bacteria,1MX1J@1224|Proteobacteria,1RSCF@1236|Gammaproteobacteria,1X4TE@135614|Xanthomonadales	135614|Xanthomonadales	G	N-acylglucosamine 2-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
MMS3_k127_3657564_1	1123073.KB899242_gene1567	1.21e-163	530.0	2DBJC@1|root,2Z9K5@2|Bacteria,1NQYW@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolase family 47	-	-	3.2.1.113	ko:K01230	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00073,M00074	R05982,R06722	-	ko00000,ko00001,ko00002,ko01000,ko04131	-	GH47	-	Glyco_hydro_47
MMS3_k127_3657564_2	661478.OP10G_2736	5.587e-109	366.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Peptidase_S8
MMS3_k127_3657564_4	1108045.GORHZ_040_00180	6.364e-104	344.0	COG0426@1|root,COG0426@2|Bacteria,2GJT6@201174|Actinobacteria	201174|Actinobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
MMS3_k127_3657564_7	290397.Adeh_2888	1.715e-38	151.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3657564_5	694427.Palpr_1308	3.941e-88	312.0	2ET12@1|root,33KJA@2|Bacteria,4P2T4@976|Bacteroidetes	976|Bacteroidetes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	OmpA_membrane,PagL
MMS3_k127_3657564_14	666684.AfiDRAFT_1547	5.097e-10	70.0	2AJHD@1|root,31A3Z@2|Bacteria,1NVFG@1224|Proteobacteria,2URW9@28211|Alphaproteobacteria,3K3T7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3657564_11	1122194.AUHU01000003_gene2268	2.893e-26	112.0	COG1396@1|root,COG1396@2|Bacteria,1P0VP@1224|Proteobacteria,1SSAM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3657564_9	211165.AJLN01000117_gene2961	3.72e-38	146.0	COG4679@1|root,COG4679@2|Bacteria,1G6N5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
MMS3_k127_3657564_13	314278.NB231_03105	1.082e-15	83.0	COG3668@1|root,COG3668@2|Bacteria,1QSS3@1224|Proteobacteria,1SRQZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3657564_15	1123054.KB907716_gene182	0.000718	48.0	2DEKY@1|root,2ZNE1@2|Bacteria,1P89E@1224|Proteobacteria,1STZ8@1236|Gammaproteobacteria,1X1YS@135613|Chromatiales	135613|Chromatiales	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
MMS3_k127_3657564_8	379066.GAU_3713	3.135e-38	148.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	Fer4,HTH_3,HTH_31
MMS3_k127_3670701_4	1047013.AQSP01000090_gene668	4.527e-122	399.0	COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_3670701_6	1047013.AQSP01000090_gene667	4.922e-94	319.0	COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria	2|Bacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMS3_k127_3670701_15	1238190.AMQY01000003_gene1627	1.364e-35	149.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1XJ89@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
MMS3_k127_3670701_17	684949.ATTJ01000001_gene2640	4.988e-32	136.0	COG2264@1|root,COG2264@2|Bacteria,1WJ0S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
MMS3_k127_3670701_5	420324.KI912031_gene2726	8.915e-118	398.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,1JQUZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS3_k127_3670701_14	717605.Theco_2404	1.005e-35	145.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,26X19@186822|Paenibacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
MMS3_k127_3670701_13	398767.Glov_2831	1.69e-57	213.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
MMS3_k127_3670701_12	204669.Acid345_2647	6.168e-66	236.0	COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria,2JP44@204432|Acidobacteriia	204432|Acidobacteriia	C	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
MMS3_k127_3670701_7	1089550.ATTH01000001_gene2287	5.118e-91	321.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1FJ16@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
MMS3_k127_3670701_18	526225.Gobs_3676	9.388e-16	92.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4ESG4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknA	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMS3_k127_3670701_20	1151117.AJLF01000001_gene1492	9.391e-13	82.0	arCOG02559@1|root,arCOG03264@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	183968|Thermococci	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
MMS3_k127_3670701_3	1128421.JAGA01000003_gene3449	2.071e-134	444.0	COG0505@1|root,COG0505@2|Bacteria,2NNMS@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383,iYO844.BSU15510	CPSase_sm_chain,GATase
MMS3_k127_3670701_0	1173264.KI913949_gene1240	0.0	1345.0	COG0458@1|root,COG0458@2|Bacteria,1G00J@1117|Cyanobacteria,1H8YN@1150|Oscillatoriales	1117|Cyanobacteria	F	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
MMS3_k127_3670701_9	671143.DAMO_0319	6.186e-75	282.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria	2|Bacteria	U	Metallo-beta-lactamase superfamily	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
MMS3_k127_3670701_16	1303518.CCALI_00810	7.114e-35	138.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP
MMS3_k127_3670701_10	1217720.ALOX01000010_gene1990	1.627e-72	254.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2JPGN@204441|Rhodospirillales	204441|Rhodospirillales	S	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
MMS3_k127_3670701_19	1242864.D187_008569	3.052e-15	79.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2YVZK@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
MMS3_k127_3670701_8	309801.trd_1369	1.34e-80	282.0	COG1235@1|root,COG1235@2|Bacteria,2G8BU@200795|Chloroflexi,27Y03@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
MMS3_k127_3670701_11	502025.Hoch_2437	5.976e-71	250.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2YV5E@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
MMS3_k127_3670701_2	234267.Acid_3249	1.273e-143	469.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
MMS3_k127_3670701_1	234267.Acid_2435	2.61e-173	553.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_3679945_17	1415779.JOMH01000001_gene81	7.137e-05	51.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria,1SS32@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_3679945_5	443143.GM18_2351	1.354e-65	229.0	COG1028@1|root,COG1028@2|Bacteria,1RA3U@1224|Proteobacteria,42TV0@68525|delta/epsilon subdivisions,2WR1B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3679945_4	1158292.JPOE01000002_gene1968	2.325e-68	246.0	COG1376@1|root,COG1376@2|Bacteria,1MVI4@1224|Proteobacteria,2VKWG@28216|Betaproteobacteria	28216|Betaproteobacteria	M	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,YkuD
MMS3_k127_3679945_11	240015.ACP_0672	7.348e-36	144.0	COG2010@1|root,COG2010@2|Bacteria,3Y4X7@57723|Acidobacteria,2JJFH@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMS3_k127_3679945_18	313612.L8106_03609	8.768e-05	54.0	2ECYT@1|root,336VT@2|Bacteria,1G9KV@1117|Cyanobacteria,1HD3I@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3679945_14	861299.J421_2365	1.875e-28	127.0	2C181@1|root,34B2S@2|Bacteria,1ZU30@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3679945_12	861299.J421_2364	2.252e-34	145.0	COG0723@1|root,COG0723@2|Bacteria,1ZU0N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
MMS3_k127_3679945_8	234267.Acid_1147	8.787e-43	160.0	COG0662@1|root,COG0662@2|Bacteria,3Y8AX@57723|Acidobacteria	57723|Acidobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3679945_9	983917.RGE_14220	2.928e-42	160.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2VTR4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
MMS3_k127_3679945_2	875328.JDM601_1602	1.745e-86	294.0	COG2020@1|root,COG2020@2|Bacteria,2GN9N@201174|Actinobacteria,2336J@1762|Mycobacteriaceae	201174|Actinobacteria	O	NnrU protein	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU
MMS3_k127_3679945_0	234267.Acid_5900	1.118e-281	905.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_3679945_10	1206777.B195_15092	4.856e-36	144.0	COG1416@1|root,COG1416@2|Bacteria,1RFD1@1224|Proteobacteria,1S7R2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfur reduction protein DsrE	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
MMS3_k127_3679945_3	1382315.JPOI01000001_gene2722	5.772e-75	261.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1WG3J@129337|Geobacillus	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.5	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
MMS3_k127_3679945_1	1267535.KB906767_gene1520	3.102e-150	491.0	COG2939@1|root,COG2939@2|Bacteria,3Y3DM@57723|Acidobacteria,2JIJH@204432|Acidobacteriia	204432|Acidobacteriia	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
MMS3_k127_3679945_15	1267535.KB906767_gene889	9.613e-26	116.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	ermC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
MMS3_k127_3679945_6	358396.C445_18543	1.624e-51	194.0	arCOG08204@1|root,arCOG08204@2157|Archaea,2XWZG@28890|Euryarchaeota,23VDX@183963|Halobacteria	183963|Halobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
MMS3_k127_3679945_7	246197.MXAN_3771	2.492e-43	169.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,42WF1@68525|delta/epsilon subdivisions,2WS1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
MMS3_k127_3679945_13	1278309.KB907099_gene2766	4.368e-29	124.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria,1SRHG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3679945_19	40571.JOEA01000023_gene7261	0.0003462	48.0	2DZDG@1|root,32V7V@2|Bacteria,2GWJ5@201174|Actinobacteria,4E7T6@85010|Pseudonocardiales	201174|Actinobacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
MMS3_k127_3812151_28	67267.JNXT01000038_gene3405	5.377e-07	62.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,2H1NS@201174|Actinobacteria	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
MMS3_k127_3812151_6	1123508.JH636440_gene2608	9.225e-122	413.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_9,Response_reg
MMS3_k127_3812151_31	1185652.USDA257_c37070	0.0009013	51.0	COG2199@1|root,COG3706@2|Bacteria,1QGKI@1224|Proteobacteria,2U3SB@28211|Alphaproteobacteria,4BN5R@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMS3_k127_3812151_14	1382356.JQMP01000004_gene323	6.141e-85	301.0	COG3804@1|root,COG3804@2|Bacteria,2GA3D@200795|Chloroflexi,27YZV@189775|Thermomicrobia	189775|Thermomicrobia	S	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
MMS3_k127_3812151_5	861299.J421_1935	8.107e-145	488.0	COG2091@1|root,COG2091@2|Bacteria,1ZU9H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3812151_4	1218074.BAXZ01000010_gene2446	8.825e-165	537.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,1JZVQ@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_3812151_9	1047013.AQSP01000123_gene1525	6.362e-110	385.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
MMS3_k127_3812151_2	330214.NIDE2536	2.46e-234	743.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
MMS3_k127_3812151_29	204669.Acid345_3199	1.807e-06	58.0	2ED8Q@1|root,33759@2|Bacteria,3Y5NT@57723|Acidobacteria,2JJWR@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
MMS3_k127_3812151_22	1379698.RBG1_1C00001G1213	3.349e-34	143.0	COG1956@1|root,COG1956@2|Bacteria,2NPKF@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
MMS3_k127_3812151_23	1415780.JPOG01000001_gene3194	1.645e-23	115.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1X4M7@135614|Xanthomonadales	135614|Xanthomonadales	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS3_k127_3812151_15	479434.Sthe_2631	1.868e-81	297.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi,27XF7@189775|Thermomicrobia	189775|Thermomicrobia	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
MMS3_k127_3812151_11	1121377.KB906409_gene894	4.663e-107	360.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_3812151_21	1173024.KI912149_gene5722	5.537e-44	171.0	COG0300@1|root,COG0300@2|Bacteria,1G7GB@1117|Cyanobacteria,1JJH1@1189|Stigonemataceae	1117|Cyanobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_3812151_18	234267.Acid_5241	7.241e-66	232.0	COG1262@1|root,COG1262@2|Bacteria	234267.Acid_5241|-	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3812151_8	1469245.JFBG01000027_gene1490	4.28e-114	390.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
MMS3_k127_3812151_26	1379701.JPJC01000021_gene3373	9.724e-17	90.0	COG2755@1|root,COG2755@2|Bacteria,1RE9P@1224|Proteobacteria,2UJZG@28211|Alphaproteobacteria,2K30X@204457|Sphingomonadales	204457|Sphingomonadales	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMS3_k127_3812151_16	1123503.KB908058_gene957	1.613e-79	274.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,2KF7M@204458|Caulobacterales	204458|Caulobacterales	K	Transcriptional regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_3812151_10	644968.DFW101_2310	1.366e-107	366.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42R77@68525|delta/epsilon subdivisions,2WMVR@28221|Deltaproteobacteria,2MAKU@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Integral membrane sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_3812151_7	234267.Acid_5786	1.644e-119	401.0	COG0265@1|root,COG0265@2|Bacteria,3Y2WB@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_3812151_19	290397.Adeh_4303	3.022e-59	217.0	COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,43DY0@68525|delta/epsilon subdivisions,2X918@28221|Deltaproteobacteria,2Z1ER@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_3812151_13	886293.Sinac_5036	6.649e-89	310.0	2AAEK@1|root,3169S@2|Bacteria,2J1M3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3812151_1	639030.JHVA01000001_gene841	5.148e-239	766.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
MMS3_k127_3812151_24	234267.Acid_7216	5.338e-21	98.0	COG3115@1|root,COG3115@2|Bacteria	2|Bacteria	D	cell septum assembly	-	-	-	ko:K02487,ko:K06596,ko:K08372	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko02022,ko02035	-	-	-	FliO,SPOR,ZipA_C
MMS3_k127_3812151_25	706587.Desti_2926	1.477e-20	92.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42WGE@68525|delta/epsilon subdivisions,2WRF1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
MMS3_k127_3812151_12	1125863.JAFN01000001_gene1973	1.952e-101	344.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
MMS3_k127_3812151_27	314230.DSM3645_09147	3.743e-15	88.0	COG0789@1|root,COG3118@1|root,COG0789@2|Bacteria,COG3118@2|Bacteria,2IZBY@203682|Planctomycetes	203682|Planctomycetes	K	O-linked GlcNAc transferase	-	-	-	-	-	-	-	-	-	-	-	-	BRCT,MerR_1,TPR_16
MMS3_k127_3812151_17	1382359.JIAL01000001_gene1654	2.812e-76	267.0	COG0837@1|root,COG0837@2|Bacteria,3Y3P1@57723|Acidobacteria,2JIE1@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
MMS3_k127_3812151_3	760117.JN27_09180	9.717e-203	651.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2VPBK@28216|Betaproteobacteria,476GH@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
MMS3_k127_3812151_20	234267.Acid_0694	2.308e-46	172.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
MMS3_k127_3812151_0	1242864.D187_008863	0.0	1380.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1Q2ZJ@1224|Proteobacteria,438P5@68525|delta/epsilon subdivisions,2X8TH@28221|Deltaproteobacteria,2YXE6@29|Myxococcales	28221|Deltaproteobacteria	CEH	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
MMS3_k127_3812151_30	535289.Dtpsy_3452	5.832e-05	56.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,2VR0I@28216|Betaproteobacteria,4AFQ2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3824344_46	316056.RPC_1345	2.333e-11	70.0	COG0350@1|root,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,2TV5U@28211|Alphaproteobacteria,3JTW0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
MMS3_k127_3824344_9	1254432.SCE1572_06495	3.114e-121	394.0	COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,43E8K@68525|delta/epsilon subdivisions,2X9BJ@28221|Deltaproteobacteria,2YXFG@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
MMS3_k127_3824344_43	1121920.AUAU01000026_gene1478	2.852e-17	92.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_3824344_2	1267535.KB906767_gene5499	1.979e-203	644.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863,PQQ_2,PQQ_3
MMS3_k127_3824344_17	1121920.AUAU01000010_gene123	5.636e-76	259.0	COG0231@1|root,COG0231@2|Bacteria,3Y2GH@57723|Acidobacteria	57723|Acidobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
MMS3_k127_3824344_21	1242864.D187_010314	2.479e-66	229.0	COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria,42ZTP@68525|delta/epsilon subdivisions,2WV97@28221|Deltaproteobacteria,2YWVF@29|Myxococcales	28221|Deltaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_3824344_13	378806.STAUR_6112	2.63e-100	335.0	COG2267@1|root,COG2267@2|Bacteria,1PDD2@1224|Proteobacteria,430GU@68525|delta/epsilon subdivisions,2WW4T@28221|Deltaproteobacteria,2YYCY@29|Myxococcales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMS3_k127_3824344_25	502025.Hoch_6859	4.924e-57	204.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2YV8N@29|Myxococcales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
MMS3_k127_3824344_29	153948.NAL212_1488	2.482e-50	188.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
MMS3_k127_3824344_23	153948.NAL212_1487	4.55e-62	224.0	COG2301@1|root,COG2301@2|Bacteria,1RJQ8@1224|Proteobacteria,2VUSY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
MMS3_k127_3824344_51	1123060.JONP01000012_gene2733	0.0006267	51.0	COG4122@1|root,COG4122@2|Bacteria,1RJYJ@1224|Proteobacteria,2UB29@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
MMS3_k127_3824344_50	1128427.KB904821_gene1537	5.581e-05	52.0	2DQ7S@1|root,3355J@2|Bacteria,1GA7T@1117|Cyanobacteria,1HCAP@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
MMS3_k127_3824344_49	1122915.AUGY01000047_gene1436	1.071e-08	60.0	2DRDY@1|root,33BC0@2|Bacteria,1VFFN@1239|Firmicutes,4HP9H@91061|Bacilli,26ZSQ@186822|Paenibacillaceae	91061|Bacilli	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
MMS3_k127_3824344_39	765912.Thimo_3580	5.82e-31	135.0	COG1493@1|root,COG1493@2|Bacteria,1RE0J@1224|Proteobacteria,1SBIT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3824344_14	1121939.L861_02640	7.106e-100	350.0	COG0367@1|root,COG0367@2|Bacteria,1R77U@1224|Proteobacteria,1S5ZY@1236|Gammaproteobacteria,1XPIW@135619|Oceanospirillales	135619|Oceanospirillales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
MMS3_k127_3824344_37	1110502.TMO_3290	1.653e-38	159.0	COG0463@1|root,COG0463@2|Bacteria,1QV5U@1224|Proteobacteria,2TWAG@28211|Alphaproteobacteria,2JZ1J@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3824344_20	338966.Ppro_0062	7.344e-68	247.0	COG1216@1|root,COG1216@2|Bacteria,1PIZU@1224|Proteobacteria,42ZNA@68525|delta/epsilon subdivisions,2WUX2@28221|Deltaproteobacteria,43VTF@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
MMS3_k127_3824344_6	58123.JOFJ01000027_gene2790	5.259e-134	439.0	COG0531@1|root,COG0531@2|Bacteria,2H98W@201174|Actinobacteria,4EN0D@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMS3_k127_3824344_8	1163407.UU7_09050	2.49e-123	406.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1S9NJ@1236|Gammaproteobacteria,1X5C8@135614|Xanthomonadales	135614|Xanthomonadales	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.12.1,1.14.15.7	ko:K00499,ko:K16319	ko00260,ko00627,ko01120,map00260,map00627,map01120	M00637	R00823,R00825,R07409	RC00087,RC00192	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
MMS3_k127_3824344_5	1449355.JQNR01000005_gene4892	1.497e-141	458.0	COG2355@1|root,COG2355@2|Bacteria,2GN82@201174|Actinobacteria	201174|Actinobacteria	E	Dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMS3_k127_3824344_33	861299.J421_5873	3.77e-44	171.0	2C804@1|root,32VPI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
MMS3_k127_3824344_7	861299.J421_4428	5.484e-126	420.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS3_k127_3824344_1	1123277.KB893187_gene2689	6.528e-257	812.0	COG0142@1|root,COG5621@1|root,COG0142@2|Bacteria,COG5621@2|Bacteria,4NKGY@976|Bacteroidetes	976|Bacteroidetes	H	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9,polyprenyl_synt
MMS3_k127_3824344_10	1123252.ATZF01000006_gene706	7.6e-111	366.0	COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,4HDPM@91061|Bacilli,27D7W@186824|Thermoactinomycetaceae	91061|Bacilli	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
MMS3_k127_3824344_0	1040989.AWZU01000011_gene4140	2.707e-285	891.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,3JR7Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	symbiont process	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
MMS3_k127_3824344_48	1304872.JAGC01000003_gene3461	5.043e-10	68.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,42X36@68525|delta/epsilon subdivisions,2WSNU@28221|Deltaproteobacteria,2MDMZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3824344_38	1205680.CAKO01000038_gene1840	1.794e-32	136.0	2E3ZS@1|root,32YWP@2|Bacteria,1NAZV@1224|Proteobacteria,2UGW3@28211|Alphaproteobacteria,2JXCF@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3824344_22	1267535.KB906767_gene2401	2.826e-66	241.0	COG2148@1|root,COG2148@2|Bacteria,3Y3GZ@57723|Acidobacteria,2JIAU@204432|Acidobacteriia	204432|Acidobacteriia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
MMS3_k127_3824344_4	1282360.ABAC460_19840	7.267e-166	560.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria	1224|Proteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_3824344_19	460265.Mnod_3175	1.936e-69	267.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2TS7U@28211|Alphaproteobacteria,1JR1G@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	TIGRFAM glucose-1-phosphate cytidylyltransferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
MMS3_k127_3824344_11	926550.CLDAP_10490	2.243e-108	360.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yfnG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_3824344_15	1229909.NSED_09965	6.218e-98	348.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_3824344_40	443144.GM21_3192	7.626e-27	123.0	COG1596@1|root,COG1596@2|Bacteria,1RDXY@1224|Proteobacteria,43DN5@68525|delta/epsilon subdivisions,2X6GD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Polysaccharide export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
MMS3_k127_3824344_41	426117.M446_4029	2.149e-21	109.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1PIAH@1224|Proteobacteria,2UZI6@28211|Alphaproteobacteria,1JUFJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	protein tyrosine kinase activity	-	-	-	ko:K20998	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Wzz
MMS3_k127_3824344_45	1238186.AOCN01000012_gene1303	9.323e-12	74.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4FNA7@85023|Microbacteriaceae	201174|Actinobacteria	D	Chain length determinant protein	wcoI	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,ParA,Wzz
MMS3_k127_3824344_26	426117.M446_4035	1.419e-53	208.0	COG1216@1|root,COG1216@2|Bacteria,1R42U@1224|Proteobacteria,2V1KZ@28211|Alphaproteobacteria,1JXA5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3824344_27	247490.KSU1_C0426	2.21e-53	202.0	COG1131@1|root,COG1131@2|Bacteria,2IZYW@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,DUF4162
MMS3_k127_3824344_36	395493.BegalDRAFT_0500	1.876e-39	162.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_3824344_24	460265.Mnod_3180	1.851e-58	222.0	COG3307@1|root,COG3307@2|Bacteria,1NMAY@1224|Proteobacteria,2URM7@28211|Alphaproteobacteria,1JUF0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_3824344_12	460265.Mnod_3179	1.455e-102	361.0	COG3534@1|root,COG3534@2|Bacteria,1PPWJ@1224|Proteobacteria,2VFZM@28211|Alphaproteobacteria,1JYY1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
MMS3_k127_3824344_34	460265.Mnod_3170	3.576e-43	174.0	COG0438@1|root,COG0438@2|Bacteria,1PP35@1224|Proteobacteria,2V1KU@28211|Alphaproteobacteria,1JX9Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	PFAM glycosyl transferase group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
MMS3_k127_3824344_47	741091.Rahaq_3590	8.423e-11	76.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,1RUDN@1236|Gammaproteobacteria,3FGJT@34037|Rahnella	1236|Gammaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_3824344_42	1121272.KB903261_gene5886	7.754e-20	102.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS3_k127_3824344_31	426117.M446_4024	5.569e-48	185.0	COG1215@1|root,COG1215@2|Bacteria,1PFWZ@1224|Proteobacteria,2V1PB@28211|Alphaproteobacteria,1JXDE@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3824344_28	460265.Mnod_3181	5.91e-53	210.0	COG1216@1|root,COG1216@2|Bacteria,1R6SJ@1224|Proteobacteria,2U47V@28211|Alphaproteobacteria,1JU3E@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
MMS3_k127_3824344_18	426117.M446_4023	3.43e-74	263.0	COG0438@1|root,COG0438@2|Bacteria,1PNSZ@1224|Proteobacteria,2V1BX@28211|Alphaproteobacteria,1JWYC@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
MMS3_k127_3824344_44	644282.Deba_3075	1.169e-13	83.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMS3_k127_3824344_16	426117.M446_4022	4.928e-94	323.0	COG0438@1|root,COG0438@2|Bacteria,1PP4H@1224|Proteobacteria,2V1MT@28211|Alphaproteobacteria,1JXB3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_3824344_30	1510531.JQJJ01000008_gene4101	2.678e-49	181.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2U735@28211|Alphaproteobacteria,3JY2H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YCII-related domain	MA20_04055	-	-	-	-	-	-	-	-	-	-	-	YCII
MMS3_k127_3824344_32	63737.Npun_R2128	1.586e-46	172.0	COG2764@1|root,COG2764@2|Bacteria,1G76J@1117|Cyanobacteria,1HS99@1161|Nostocales	1117|Cyanobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
MMS3_k127_3824344_3	479434.Sthe_2955	4.895e-183	580.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3824344_35	1005048.CFU_2574	5.261e-42	156.0	COG3795@1|root,COG3795@2|Bacteria,1N2T1@1224|Proteobacteria,2VUKT@28216|Betaproteobacteria,4756N@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMS3_k127_3873119_4	234267.Acid_1264	6.811e-48	175.0	COG1063@1|root,COG1063@2|Bacteria,3Y30Y@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3873119_3	639030.JHVA01000001_gene2165	4.866e-48	182.0	COG0726@1|root,COG0726@2|Bacteria,3Y4FK@57723|Acidobacteria,2JJ5K@204432|Acidobacteriia	204432|Acidobacteriia	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
MMS3_k127_3873119_2	204669.Acid345_1830	1.242e-72	261.0	COG0845@1|root,COG0845@2|Bacteria,3Y43D@57723|Acidobacteria,2JHRU@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
MMS3_k127_3873119_7	1382359.JIAL01000001_gene515	1.965e-25	119.0	COG0457@1|root,COG0457@2|Bacteria,3Y4RD@57723|Acidobacteria,2JJAQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
MMS3_k127_3873119_1	1267535.KB906767_gene5191	3.664e-93	321.0	COG0577@1|root,COG0577@2|Bacteria,3Y3ZQ@57723|Acidobacteria,2JHMD@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_3873119_5	1267535.KB906767_gene1305	9.606e-42	169.0	COG1538@1|root,COG1538@2|Bacteria,3Y4MP@57723|Acidobacteria	57723|Acidobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_3873119_0	234267.Acid_7504	3.978e-209	660.0	COG1032@1|root,COG1032@2|Bacteria,3Y2QU@57723|Acidobacteria	57723|Acidobacteria	C	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_3873119_6	240015.ACP_3296	4.789e-28	121.0	COG2510@1|root,COG2510@2|Bacteria	2|Bacteria	EG	membrane	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
MMS3_k127_3873119_8	1415630.U771_06780	0.0006895	50.0	COG2510@1|root,COG2510@2|Bacteria,1R13B@1224|Proteobacteria,1T4U8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS3_k127_3925240_28	1267535.KB906767_gene328	1.618e-55	209.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_3925240_19	502025.Hoch_1848	2.551e-74	255.0	COG0572@1|root,COG0572@2|Bacteria,1MWCH@1224|Proteobacteria,42T0E@68525|delta/epsilon subdivisions,2WPTV@28221|Deltaproteobacteria,2YUY9@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.19,2.7.1.48	ko:K00855,ko:K00876	ko00240,ko00710,ko00983,ko01100,ko01120,ko01200,map00240,map00710,map00983,map01100,map01120,map01200	M00165,M00166	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01523,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
MMS3_k127_3925240_54	324602.Caur_3617	3.504e-20	101.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_3925240_56	1454007.JAUG01000062_gene587	3.665e-17	89.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1IT6C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
MMS3_k127_3925240_1	1288494.EBAPG3_26320	9.917e-243	784.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,37225@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
MMS3_k127_3925240_44	1254432.SCE1572_36795	1.741e-34	138.0	COG0517@1|root,COG0517@2|Bacteria,1QQRM@1224|Proteobacteria,42TVT@68525|delta/epsilon subdivisions,2WQBQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMS3_k127_3925240_15	204669.Acid345_3716	8.245e-84	289.0	28HTF@1|root,2Z80A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3925240_63	1150474.JQJI01000024_gene1581	1.885e-05	53.0	29Z3U@1|root,30M1E@2|Bacteria,2GEF9@200918|Thermotogae	1150474.JQJI01000024_gene1581|-	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3925240_57	404589.Anae109_0684	5.372e-15	82.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTY9@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3925240_7	234267.Acid_0122	5.895e-124	425.0	COG4206@1|root,COG4206@2|Bacteria,3Y42S@57723|Acidobacteria	57723|Acidobacteria	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_3925240_9	1267535.KB906767_gene4067	1.942e-107	360.0	COG0668@1|root,COG0668@2|Bacteria,3Y375@57723|Acidobacteria,2JHWN@204432|Acidobacteriia	204432|Acidobacteriia	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
MMS3_k127_3925240_27	457429.ABJI02000178_gene3935	7.682e-56	199.0	2AZF8@1|root,31RP4@2|Bacteria,2IH9G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3925240_2	33898.JRHJ01000089_gene2618	1.097e-227	721.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase	wcoR	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
MMS3_k127_3925240_64	266265.Bxe_B3022	0.0001275	51.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,1QY4K@1224|Proteobacteria,2WHC6@28216|Betaproteobacteria,1KG74@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
MMS3_k127_3925240_23	1123229.AUBC01000006_gene986	6.446e-64	234.0	COG1252@1|root,COG1252@2|Bacteria,1QUKT@1224|Proteobacteria,2TW32@28211|Alphaproteobacteria,3JZTJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
MMS3_k127_3925240_59	413816.BBJP01000003_gene180	2.005e-13	78.0	COG0642@1|root,arCOG02364@1|root,arCOG02327@2157|Archaea,arCOG02364@2157|Archaea,2XVUF@28890|Euryarchaeota,23UIE@183963|Halobacteria	183963|Halobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_7TM,PAS,PAS_4,PAS_8,Response_reg
MMS3_k127_3925240_61	32049.SYNPCC7002_A2229	1.254e-08	58.0	COG1826@1|root,COG1826@2|Bacteria,1G93D@1117|Cyanobacteria,1H250@1129|Synechococcus	1117|Cyanobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_3925240_50	1168034.FH5T_06885	1.217e-24	119.0	28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,2FQ08@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
MMS3_k127_3925240_18	1382356.JQMP01000003_gene2027	1.899e-75	259.0	COG0412@1|root,COG0412@2|Bacteria,2G9WC@200795|Chloroflexi,27Z94@189775|Thermomicrobia	189775|Thermomicrobia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS3_k127_3925240_62	706587.Desti_3287	1.086e-06	54.0	COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,43CIK@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	DJ-1/PfpI family	inhA	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
MMS3_k127_3925240_12	1121403.AUCV01000014_gene4608	4.263e-91	327.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2MHUB@213118|Desulfobacterales	28221|Deltaproteobacteria	D	G-rich domain on putative tyrosine kinase	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
MMS3_k127_3925240_45	671143.DAMO_2346	4.352e-33	145.0	COG0484@1|root,COG3307@1|root,COG0484@2|Bacteria,COG3307@2|Bacteria,2NPHS@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	DnaJ,Wzy_C
MMS3_k127_3925240_38	768671.ThimaDRAFT_3012	2.059e-42	170.0	2C8KX@1|root,32RMF@2|Bacteria,1N68G@1224|Proteobacteria,1SDSS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
MMS3_k127_3925240_65	2903.EOD36757	0.0001675	56.0	KOG2177@1|root,KOG2177@2759|Eukaryota	2759|Eukaryota	O	zinc ion binding	-	-	-	-	-	-	-	-	-	-	-	-	BTB,Lactonase,NHL,SGL
MMS3_k127_3925240_42	1380370.JIBA01000003_gene2713	1.003e-36	163.0	COG3055@1|root,COG3507@1|root,COG3055@2|Bacteria,COG3507@2|Bacteria,2IARJ@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3925240_52	292459.STH3284	2.295e-23	109.0	COG2120@1|root,COG2120@2|Bacteria,1TPSJ@1239|Firmicutes,24K8W@186801|Clostridia	186801|Clostridia	S	TIGRFAM bacillithiol biosynthesis deacetylase BshB2	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	DUF1806,PIG-L
MMS3_k127_3925240_53	1385517.N800_04530	8.963e-21	103.0	COG1493@1|root,COG1493@2|Bacteria,1RE0J@1224|Proteobacteria,1SBIT@1236|Gammaproteobacteria,1XBG2@135614|Xanthomonadales	135614|Xanthomonadales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3925240_35	1183438.GKIL_2157	1.187e-44	177.0	COG4076@1|root,COG4076@2|Bacteria,1G4RK@1117|Cyanobacteria	1117|Cyanobacteria	J	PRMT5 arginine-N-methyltransferase	-	-	2.1.1.319	ko:K11434	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	PRMT5_C,PrmA
MMS3_k127_3925240_11	1167006.UWK_01777	2.179e-93	331.0	COG0367@1|root,COG0367@2|Bacteria,1R77U@1224|Proteobacteria,4305Y@68525|delta/epsilon subdivisions,2WVE7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
MMS3_k127_3925240_58	1173028.ANKO01000112_gene4859	1.725e-14	78.0	2DRDY@1|root,33BC0@2|Bacteria,1G9R7@1117|Cyanobacteria,1HCUI@1150|Oscillatoriales	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
MMS3_k127_3925240_29	795359.TOPB45_0362	1.986e-54	206.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	1.3.1.101,1.3.7.11,5.5.1.18	ko:K06444,ko:K17830	ko00564,ko00906,ko01100,ko01110,map00564,map00906,map01100,map01110	-	R06960,R06963,R07840,R10325,R10326,R10331	RC01612,RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8,Pyr_redox_2,Trp_halogenase
MMS3_k127_3925240_34	795359.TOPB45_0361	1.29e-46	178.0	COG2148@1|root,COG2148@2|Bacteria,2GHZH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
MMS3_k127_3925240_24	756272.Plabr_4164	6.501e-64	239.0	COG0438@1|root,COG0438@2|Bacteria,2IZS5@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
MMS3_k127_3925240_5	1123368.AUIS01000027_gene1355	3.504e-197	641.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
MMS3_k127_3925240_37	215803.DB30_3213	2.176e-43	173.0	COG4122@1|root,COG4122@2|Bacteria,1N96U@1224|Proteobacteria,42XTJ@68525|delta/epsilon subdivisions,2WTH9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
MMS3_k127_3925240_46	278957.ABEA03000016_gene2378	6.234e-33	144.0	COG0438@1|root,COG0438@2|Bacteria,46WHJ@74201|Verrucomicrobia,3K9HF@414999|Opitutae	414999|Opitutae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_3925240_30	1396141.BATP01000056_gene3213	1.262e-51	198.0	COG0438@1|root,COG0438@2|Bacteria,46VET@74201|Verrucomicrobia,2IUKI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
MMS3_k127_3925240_60	1123248.KB893314_gene3341	6.408e-10	72.0	2E1YZ@1|root,32X7I@2|Bacteria,4NTC5@976|Bacteroidetes,1IXUN@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3925240_47	485914.Hmuk_0077	5.779e-32	140.0	COG0438@1|root,arCOG01403@2157|Archaea,2Y3QD@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_3925240_55	246197.MXAN_1027	4.104e-19	103.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,42M2P@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_3925240_22	1147.D082_21670	1.628e-67	259.0	COG0438@1|root,COG0438@2|Bacteria,1G222@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_3925240_43	489825.LYNGBM3L_52710	9.354e-35	144.0	COG2518@1|root,COG2518@2|Bacteria,1GR78@1117|Cyanobacteria,1HE58@1150|Oscillatoriales	1117|Cyanobacteria	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_21
MMS3_k127_3925240_17	1205680.CAKO01000006_gene3344	2.081e-77	276.0	COG0438@1|root,COG0438@2|Bacteria,1Q0M0@1224|Proteobacteria,2UEYP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3925240_36	706587.Desti_5230	1.044e-43	181.0	COG0535@1|root,COG0535@2|Bacteria,1RG5U@1224|Proteobacteria,42RKR@68525|delta/epsilon subdivisions,2WNUX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
MMS3_k127_3925240_20	1270196.JCKI01000006_gene2599	9.269e-74	264.0	COG0438@1|root,COG0438@2|Bacteria,4NIWP@976|Bacteroidetes,1IS8B@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_3925240_32	1205680.CAKO01000006_gene3342	3.877e-49	192.0	COG0438@1|root,COG0438@2|Bacteria,1MYJ6@1224|Proteobacteria,2UMC7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_3925240_16	221288.JH992901_gene882	9.346e-80	287.0	COG0438@1|root,COG0438@2|Bacteria,1G25Y@1117|Cyanobacteria,1JJWS@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_3925240_31	1347342.BN863_29230	2.401e-50	192.0	COG1216@1|root,COG1216@2|Bacteria,4PMPA@976|Bacteroidetes,1IKQF@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3925240_49	439235.Dalk_2049	3.081e-25	120.0	COG0438@1|root,COG0438@2|Bacteria,1PFC7@1224|Proteobacteria,439Z9@68525|delta/epsilon subdivisions,2WWVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_3925240_40	1434325.AZQN01000009_gene4046	2.616e-41	163.0	COG2890@1|root,COG2890@2|Bacteria,4PKQD@976|Bacteroidetes,47NKD@768503|Cytophagia	976|Bacteroidetes	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
MMS3_k127_3925240_10	1229172.JQFA01000004_gene1731	3.378e-101	348.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
MMS3_k127_3925240_13	234267.Acid_4640	3.905e-89	305.0	COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
MMS3_k127_3925240_8	414684.RC1_4027	1.976e-118	405.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JW1S@204441|Rhodospirillales	204441|Rhodospirillales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
MMS3_k127_3925240_33	880072.Desac_1767	1.831e-48	184.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,2MS67@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Polysaccharide export protein	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
MMS3_k127_3925240_39	404589.Anae109_3404	1.607e-41	167.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YUPC@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	crdA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3925240_48	767817.Desgi_3101	2.263e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3925240_25	448385.sce2777	2.095e-62	230.0	COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,42RAF@68525|delta/epsilon subdivisions,2WN7G@28221|Deltaproteobacteria,2Z09C@29|Myxococcales	28221|Deltaproteobacteria	H	Site-specific DNA-methyltransferase (Adenine-specific)	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
MMS3_k127_3925240_21	204669.Acid345_1561	3.047e-71	258.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria,2JIVB@204432|Acidobacteriia	204432|Acidobacteriia	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
MMS3_k127_3925240_14	204669.Acid345_1560	1.042e-87	294.0	COG0740@1|root,COG0740@2|Bacteria,3Y2SY@57723|Acidobacteria,2JHPB@204432|Acidobacteriia	204432|Acidobacteriia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_3925240_6	1089553.Tph_c04650	3.371e-169	540.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,42EU3@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
MMS3_k127_3925240_0	880072.Desac_0419	4.823e-291	915.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MQZP@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMS3_k127_3925240_41	1196323.ALKF01000189_gene1174	3.578e-39	155.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,26RHP@186822|Paenibacillaceae	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
MMS3_k127_3925240_3	1267535.KB906767_gene3177	2.324e-227	710.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
MMS3_k127_3925240_51	555079.Toce_2074	2.993e-24	104.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,42H2T@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
MMS3_k127_3925240_26	292459.STH1622	1.936e-58	224.0	COG0457@1|root,COG3359@1|root,COG0457@2|Bacteria,COG3359@2|Bacteria,1TQQU@1239|Firmicutes	1239|Firmicutes	L	Exonuclease	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
MMS3_k127_3925240_4	234267.Acid_0769	3.022e-224	712.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,3Y61D@57723|Acidobacteria	57723|Acidobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
MMS3_k127_3984159_2	243231.GSU0567	2.027e-82	280.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,43SFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
MMS3_k127_3984159_1	1313301.AUGC01000003_gene2172	1.475e-100	361.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
MMS3_k127_3984159_0	269799.Gmet_3221	5.182e-101	343.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3984159_4	555779.Dthio_PD1896	2.427e-23	103.0	2CCSR@1|root,32RWC@2|Bacteria,1N8A2@1224|Proteobacteria,42W3G@68525|delta/epsilon subdivisions,2WSEI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMS3_k127_3984159_3	649638.Trad_0799	3.391e-43	165.0	COG0500@1|root,COG2226@2|Bacteria,1WIF9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Ykof
MMS3_k127_3991628_21	1198114.AciX9_2892	4.602e-93	326.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
MMS3_k127_3991628_28	1198114.AciX9_2897	1.537e-75	275.0	COG1404@1|root,COG5164@1|root,COG1404@2|Bacteria,COG5164@2|Bacteria,3Y5WB@57723|Acidobacteria,2JK6I@204432|Acidobacteriia	204432|Acidobacteriia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
MMS3_k127_3991628_15	234267.Acid_3456	4.089e-105	364.0	COG0747@1|root,COG0747@2|Bacteria,3Y44K@57723|Acidobacteria	57723|Acidobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3991628_35	1158338.JNLJ01000005_gene1752	5.328e-58	213.0	COG0601@1|root,COG0601@2|Bacteria,2G3MF@200783|Aquificae	200783|Aquificae	P	PFAM binding-protein-dependent transport systems inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_3991628_36	648996.Theam_0454	5.841e-58	215.0	COG1173@1|root,COG1173@2|Bacteria,2G3I0@200783|Aquificae	200783|Aquificae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_3991628_27	1125863.JAFN01000001_gene1971	8.038e-77	269.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria	1224|Proteobacteria	EM	Belongs to the DapA family	yagE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575	4.1.2.28,4.3.3.7	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01782,R10147	RC00307,RC00572,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_3991628_16	1123242.JH636435_gene3016	7.013e-104	349.0	COG0075@1|root,COG0075@2|Bacteria,2IYEK@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
MMS3_k127_3991628_19	1163617.SCD_n00733	1.383e-94	330.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
MMS3_k127_3991628_52	1210884.HG799468_gene13714	3.784e-14	83.0	COG4900@1|root,COG4900@2|Bacteria,2IZSC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3991628_44	1123261.AXDW01000004_gene2763	4.382e-30	128.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,1X7RI@135614|Xanthomonadales	135614|Xanthomonadales	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
MMS3_k127_3991628_33	330214.NIDE2766	6.534e-70	241.0	COG1403@1|root,COG1403@2|Bacteria,3J0VM@40117|Nitrospirae	40117|Nitrospirae	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
MMS3_k127_3991628_22	1267535.KB906767_gene1016	1.31e-88	303.0	COG3391@1|root,COG3391@2|Bacteria,3Y99Z@57723|Acidobacteria,2JP6W@204432|Acidobacteriia	204432|Acidobacteriia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3991628_9	1121428.DESHY_20060___1	2.391e-142	467.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,262ZX@186807|Peptococcaceae	186801|Clostridia	E	PFAM Amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
MMS3_k127_3991628_20	404589.Anae109_1532	7.225e-94	321.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,42PNZ@68525|delta/epsilon subdivisions,2WM13@28221|Deltaproteobacteria,2YUDU@29|Myxococcales	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
MMS3_k127_3991628_1	635013.TherJR_2732	0.0	1194.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMS3_k127_3991628_23	338963.Pcar_2343	2.681e-84	289.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria,43S89@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
MMS3_k127_3991628_56	463191.SSEG_07885	0.0003772	49.0	COG1366@1|root,COG1366@2|Bacteria,2GQAG@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
MMS3_k127_3991628_38	240015.ACP_1893	7.418e-39	156.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria,2JJAJ@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3991628_14	519989.ECTPHS_11717	1.009e-107	363.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1WVUW@135613|Chromatiales	135613|Chromatiales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
MMS3_k127_3991628_43	984962.XP_009549428.1	2.783e-30	133.0	COG0125@1|root,KOG3327@2759|Eukaryota,39U2H@33154|Opisthokonta,3P2YY@4751|Fungi,3V0X5@5204|Basidiomycota,228D0@155619|Agaricomycetes,3H4NY@355688|Agaricomycetes incertae sedis	4751|Fungi	F	Thymidylate kinase	CDC8	GO:0003674,GO:0003824,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
MMS3_k127_3991628_39	240015.ACP_2058	8.813e-39	155.0	COG1040@1|root,COG1040@2|Bacteria,3Y4SY@57723|Acidobacteria,2JJM7@204432|Acidobacteriia	204432|Acidobacteriia	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
MMS3_k127_3991628_45	204669.Acid345_0022	2.133e-29	124.0	COG0799@1|root,COG0799@2|Bacteria,3Y5SD@57723|Acidobacteria,2JJ9Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
MMS3_k127_3991628_41	1121423.JONT01000001_gene1942	5.843e-33	147.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,261W4@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS3_k127_3991628_12	1121468.AUBR01000001_gene523	3.149e-119	392.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,42F3Z@68295|Thermoanaerobacterales	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
MMS3_k127_3991628_42	639030.JHVA01000001_gene2413	5.526e-32	127.0	COG0211@1|root,COG0211@2|Bacteria,3Y5D8@57723|Acidobacteria,2JJPG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
MMS3_k127_3991628_50	1460634.JCM19037_1504	1.671e-19	92.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli	91061|Bacilli	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
MMS3_k127_3991628_30	1121430.JMLG01000026_gene27	9.408e-74	263.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,260T7@186807|Peptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
MMS3_k127_3991628_2	671143.DAMO_0060	3.09e-263	833.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168,ko:K07479	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
MMS3_k127_3991628_6	1382304.JNIL01000001_gene614	1.357e-167	539.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,277XV@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
MMS3_k127_3991628_26	404380.Gbem_0470	6.392e-80	278.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_3991628_10	1125863.JAFN01000001_gene2828	4.252e-137	453.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43AW1@68525|delta/epsilon subdivisions,2X6A7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3991628_37	1125863.JAFN01000001_gene2827	8.493e-53	203.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
MMS3_k127_3991628_5	338963.Pcar_2038	2.968e-191	619.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,43S8W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
MMS3_k127_3991628_48	1487923.DP73_11210	6.605e-22	104.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3991628_34	552811.Dehly_0138	2.491e-61	238.0	COG4191@1|root,COG4191@2|Bacteria,2G6UY@200795|Chloroflexi,34D87@301297|Dehalococcoidia	301297|Dehalococcoidia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
MMS3_k127_3991628_40	767817.Desgi_1265	1.254e-36	149.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3991628_18	452637.Oter_3914	8.102e-97	334.0	COG0531@1|root,COG0531@2|Bacteria,46SPF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMS3_k127_3991628_32	264732.Moth_1029	5.388e-71	245.0	COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,24FS4@186801|Clostridia,42G10@68295|Thermoanaerobacterales	186801|Clostridia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
MMS3_k127_3991628_4	204669.Acid345_0212	2.235e-201	637.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria,2JIS7@204432|Acidobacteriia	204432|Acidobacteriia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
MMS3_k127_3991628_53	1121377.KB906445_gene4222	2.204e-13	83.0	COG3055@1|root,COG3291@1|root,COG4733@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Malectin,NPCBM,SLH,fn3
MMS3_k127_3991628_3	1382359.JIAL01000001_gene1070	9.565e-247	773.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria,2JIBH@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMS3_k127_3991628_8	944479.JQLX01000013_gene1447	4.335e-159	518.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2M6KR@213113|Desulfurellales	28221|Deltaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
MMS3_k127_3991628_47	290397.Adeh_0258	1.019e-22	105.0	COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2Z2BY@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
MMS3_k127_3991628_25	204669.Acid345_2474	1.89e-80	305.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
MMS3_k127_3991628_31	1267535.KB906767_gene3597	3.499e-73	282.0	COG4775@1|root,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
MMS3_k127_3991628_55	941449.dsx2_0255	0.0002518	51.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,2M8YR@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
MMS3_k127_3991628_49	1128421.JAGA01000002_gene1599	6.2e-20	104.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_3991628_54	1379698.RBG1_1C00001G1312	3.367e-06	58.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	plnP	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_3991628_7	671143.DAMO_1876	1.65e-164	537.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	nla6	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_3991628_17	671143.DAMO_1877	7.284e-101	353.0	COG5000@1|root,COG5000@2|Bacteria,2NQZA@2323|unclassified Bacteria	2|Bacteria	T	Multi-sensor signal transduction histidine kinase	ntrB	-	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
MMS3_k127_3991628_0	483219.LILAB_22395	0.0	1223.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
MMS3_k127_3991628_13	1519464.HY22_00050	6.873e-114	376.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3991628_46	195250.CM001776_gene862	4.855e-24	114.0	COG0398@1|root,COG0398@2|Bacteria,1G3R9@1117|Cyanobacteria,1H2WN@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
MMS3_k127_3991628_24	290397.Adeh_2760	4.217e-83	283.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,430ID@68525|delta/epsilon subdivisions,2WW1J@28221|Deltaproteobacteria,2YZPM@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_3991628_11	861299.J421_4169	2.725e-128	425.0	COG0531@1|root,COG0531@2|Bacteria,1ZSQW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
MMS3_k127_3991628_29	296587.XP_002499809.1	5.435e-75	269.0	2E3BA@1|root,2SAF2@2759|Eukaryota,3822D@33090|Viridiplantae,34NGR@3041|Chlorophyta	2759|Eukaryota	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
MMS3_k127_4010541_6	1121396.KB892968_gene978	6.077e-48	177.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2MJM9@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_4010541_7	326427.Cagg_1001	1.062e-44	185.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,376IX@32061|Chloroflexia	32061|Chloroflexia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4010541_10	867903.ThesuDRAFT_02359	2.476e-28	127.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMS3_k127_4010541_2	1242864.D187_002340	5.327e-110	370.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,2YU6F@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_4010541_12	234267.Acid_3730	7.463e-11	73.0	COG2304@1|root,COG2304@2|Bacteria,3Y6RY@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
MMS3_k127_4010541_11	1449049.JONW01000008_gene586	1.355e-24	114.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMS3_k127_4010541_3	1163408.UU9_10412	1.664e-94	342.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,1RPQ6@1236|Gammaproteobacteria,1X52G@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156,LPG_synthase_TM
MMS3_k127_4010541_5	1123392.AQWL01000005_gene3145	3.184e-55	212.0	COG3946@1|root,COG3946@2|Bacteria,1R7R5@1224|Proteobacteria,2VNFU@28216|Betaproteobacteria	28216|Betaproteobacteria	U	PFAM virulence factor family protein	-	-	-	-	-	-	-	-	-	-	-	-	VirJ
MMS3_k127_4010541_9	1267533.KB906736_gene933	1.259e-31	129.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,3Y2GA@57723|Acidobacteria,2JHTQ@204432|Acidobacteriia	204432|Acidobacteriia	P	ABC nitrate sulphonate bicarbonate family transporter, ATPase subunit	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
MMS3_k127_4010541_4	426117.M446_4341	2.992e-80	275.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,1MUDV@1224|Proteobacteria,2TRXZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
MMS3_k127_4010541_1	264732.Moth_0405	1.602e-145	480.0	COG4986@1|root,COG4986@2|Bacteria,1TRRR@1239|Firmicutes,248X4@186801|Clostridia,42HSS@68295|Thermoanaerobacterales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
MMS3_k127_4010541_0	1185876.BN8_04575	1.171e-219	708.0	COG3391@1|root,COG3391@2|Bacteria,4NER2@976|Bacteroidetes,47MSB@768503|Cytophagia	976|Bacteroidetes	S	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase,SGL
MMS3_k127_4010541_8	521674.Plim_1577	2.603e-36	147.0	COG1028@1|root,COG1028@2|Bacteria,2IXK3@203682|Planctomycetes	203682|Planctomycetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
MMS3_k127_4011404_21	331678.Cphamn1_0650	3.221e-37	157.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_4011404_22	237368.SCABRO_00535	3.608e-34	149.0	COG3637@1|root,COG3637@2|Bacteria,2J46X@203682|Planctomycetes	203682|Planctomycetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4011404_20	237368.SCABRO_01554	1.161e-41	171.0	COG1538@1|root,COG1538@2|Bacteria,2IZPU@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_4011404_10	941449.dsx2_0364	6.059e-99	343.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2M9X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
MMS3_k127_4011404_0	941449.dsx2_0363	0.0	1349.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2M9PX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
MMS3_k127_4011404_11	267608.RSc0196	5.685e-84	299.0	28JQB@1|root,2Z9G8@2|Bacteria,1QCH9@1224|Proteobacteria,2VJJF@28216|Betaproteobacteria,1K17Y@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4011404_16	234267.Acid_4384	1.957e-55	205.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria	57723|Acidobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_4011404_29	1124780.ANNU01000003_gene1437	3.565e-06	57.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,47J8Z@768503|Cytophagia	976|Bacteroidetes	C	PFAM Class III cytochrome C family	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
MMS3_k127_4011404_24	671143.DAMO_0802	8.036e-32	132.0	COG1622@1|root,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cupredoxin_1
MMS3_k127_4011404_9	671143.DAMO_0801	5.099e-104	357.0	COG0843@1|root,COG0843@2|Bacteria	2|Bacteria	C	heme-copper terminal oxidase activity	coxA2	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
MMS3_k127_4011404_23	401053.AciPR4_1215	7.868e-32	132.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
MMS3_k127_4011404_7	401053.AciPR4_1216	5.805e-157	510.0	COG1290@1|root,COG1290@2|Bacteria,3Y4F0@57723|Acidobacteria,2JKSY@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C
MMS3_k127_4011404_5	330214.NIDE3904	6.115e-164	526.0	COG0438@1|root,COG0438@2|Bacteria,3J0Z0@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
MMS3_k127_4011404_25	1297742.A176_04938	1.351e-30	124.0	COG1846@1|root,COG1846@2|Bacteria,1N6T5@1224|Proteobacteria,436X8@68525|delta/epsilon subdivisions,2X1MH@28221|Deltaproteobacteria,2Z1NA@29|Myxococcales	28221|Deltaproteobacteria	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMS3_k127_4011404_4	330214.NIDE3406	9.8e-236	741.0	COG0129@1|root,COG0129@2|Bacteria,3J0ES@40117|Nitrospirae	40117|Nitrospirae	EG	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
MMS3_k127_4011404_12	1121413.JMKT01000009_gene1800	2.213e-81	285.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,42PJV@68525|delta/epsilon subdivisions,2WKRG@28221|Deltaproteobacteria,2M98V@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
MMS3_k127_4011404_28	1157640.AQWO01000022_gene1662	2.352e-18	97.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase,TIG
MMS3_k127_4011404_14	485913.Krac_2610	4.645e-69	244.0	COG2513@1|root,COG2513@2|Bacteria	2|Bacteria	G	methylisocitrate lyase activity	MA20_35565	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
MMS3_k127_4011404_17	1007096.BAGW01000013_gene2420	1.487e-51	196.0	COG2515@1|root,COG2515@2|Bacteria,1UDCW@1239|Firmicutes,24BXZ@186801|Clostridia,2N6DS@216572|Oscillospiraceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
MMS3_k127_4011404_3	215803.DB30_2602	1.807e-258	820.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	otsAB	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,S6PP,Trehalose_PPase
MMS3_k127_4011404_6	1121091.AUMP01000023_gene3848	3.767e-161	521.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,4HDKW@91061|Bacilli	91061|Bacilli	Q	Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_4011404_27	243231.GSU2335	1.531e-26	115.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_4011404_19	477974.Daud_0833	1.181e-48	190.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,2629U@186807|Peptococcaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
MMS3_k127_4011404_18	1089553.Tph_c22410	8.449e-49	197.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,248F1@186801|Clostridia,42FHN@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	zurA	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	iHN637.CLJU_RS15665	ABC_tran
MMS3_k127_4011404_15	477974.Daud_1547	1.565e-68	243.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,24875@186801|Clostridia,261XQ@186807|Peptococcaceae	186801|Clostridia	P	ABC-type Mn2 Zn2 transport system, permease component	-	-	-	ko:K09816,ko:K09819,ko:K19976	ko02010,map02010	M00242,M00243,M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
MMS3_k127_4011404_13	1184267.A11Q_1722	3.449e-69	247.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2MTTG@213481|Bdellovibrionales,2WKVE@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
MMS3_k127_4011404_2	1121946.AUAX01000039_gene5782	0.0	1014.0	COG3291@1|root,COG3537@1|root,COG3291@2|Bacteria,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria,4D9YW@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
MMS3_k127_4011404_1	378806.STAUR_5331	0.0	1092.0	COG3537@1|root,COG3537@2|Bacteria,1MXCY@1224|Proteobacteria,43BAT@68525|delta/epsilon subdivisions,2X6PZ@28221|Deltaproteobacteria,2YX4I@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
MMS3_k127_4011404_26	161528.ED21_19012	1.196e-26	113.0	COG3472@1|root,COG3472@2|Bacteria,1NEVA@1224|Proteobacteria,2UKUG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	conserved protein (DUF2081)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4011404_8	925775.XVE_4789	5.808e-154	496.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,1X4VB@135614|Xanthomonadales	135614|Xanthomonadales	G	transporter	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
MMS3_k127_4016224_33	204669.Acid345_0181	6.01e-33	141.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria,2JJAP@204432|Acidobacteriia	204432|Acidobacteriia	CO	Glutathione peroxidase	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
MMS3_k127_4016224_1	502025.Hoch_6515	8.384e-156	507.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42MBP@68525|delta/epsilon subdivisions,2WTMD@28221|Deltaproteobacteria,2YZR1@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_4016224_22	1068980.ARVW01000001_gene7255	6.956e-64	232.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25
MMS3_k127_4016224_39	1382359.JIAL01000001_gene378	1.113e-11	70.0	2EQAC@1|root,33HWH@2|Bacteria,3Y5W6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4016224_18	530564.Psta_4064	4.443e-78	271.0	COG0535@1|root,COG0535@2|Bacteria,2J0M5@203682|Planctomycetes	203682|Planctomycetes	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
MMS3_k127_4016224_15	314230.DSM3645_22234	3.267e-100	338.0	COG0639@1|root,COG0639@2|Bacteria,2J22W@203682|Planctomycetes	203682|Planctomycetes	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_4016224_4	626418.bglu_2p1060	1.207e-144	481.0	COG0477@1|root,COG0477@2|Bacteria,1NS3F@1224|Proteobacteria,2WGGT@28216|Betaproteobacteria,1KIE5@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
MMS3_k127_4016224_14	234267.Acid_1495	2.715e-106	358.0	COG1131@1|root,COG1131@2|Bacteria,3Y7MA@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_4016224_11	234267.Acid_1494	4.61e-121	405.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,3Y8AT@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_4016224_5	489825.LYNGBM3L_41430	4.519e-140	456.0	COG1171@1|root,COG1171@2|Bacteria,1G22X@1117|Cyanobacteria,1H94Q@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Pyridoxal phosphate-dependent enzyme, beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_4016224_31	1121861.KB899929_gene317	2.749e-38	158.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,2TT1J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
MMS3_k127_4016224_21	234267.Acid_7537	2.534e-70	247.0	COG2717@1|root,COG2717@2|Bacteria,3Y58Y@57723|Acidobacteria	57723|Acidobacteria	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
MMS3_k127_4016224_9	518766.Rmar_0538	3.354e-125	413.0	COG2041@1|root,COG2041@2|Bacteria,4NK0M@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
MMS3_k127_4016224_27	663610.JQKO01000016_gene1576	8.243e-51	188.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2TXAA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_4016224_40	1169143.KB911035_gene2339	1.127e-11	75.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,1JZSA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GerE,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,Response_reg
MMS3_k127_4016224_29	1267535.KB906767_gene3589	2.159e-42	173.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria,2JM3F@204432|Acidobacteriia	204432|Acidobacteriia	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
MMS3_k127_4016224_30	317619.ANKN01000049_gene2830	2.606e-42	164.0	COG1073@1|root,COG1073@2|Bacteria,1G54F@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
MMS3_k127_4016224_37	1235457.C404_24130	8.172e-25	109.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2VR5U@28216|Betaproteobacteria,1K2B1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Nuclear protein SET	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
MMS3_k127_4016224_36	1382356.JQMP01000004_gene533	3.954e-28	118.0	COG1547@1|root,COG1547@2|Bacteria,2GAFU@200795|Chloroflexi,27YQW@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
MMS3_k127_4016224_32	1267535.KB906767_gene216	3.083e-36	156.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
MMS3_k127_4016224_10	1267535.KB906767_gene2503	7.687e-125	411.0	COG0535@1|root,COG0535@2|Bacteria,3Y3TY@57723|Acidobacteria,2JHZQ@204432|Acidobacteriia	204432|Acidobacteriia	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
MMS3_k127_4016224_6	1382359.JIAL01000001_gene3006	1.469e-131	428.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
MMS3_k127_4016224_41	349161.Dred_1500	4.216e-08	64.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,249I4@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4
MMS3_k127_4016224_23	671143.DAMO_1814	5.548e-62	223.0	COG1639@1|root,COG1639@2|Bacteria,2NRI1@2323|unclassified Bacteria	2|Bacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
MMS3_k127_4016224_42	243231.GSU3549	1.865e-05	53.0	2EN8Q@1|root,33FWH@2|Bacteria,1NJ9J@1224|Proteobacteria,42XE1@68525|delta/epsilon subdivisions,2WT2P@28221|Deltaproteobacteria,43VKH@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4016224_0	234267.Acid_7035	0.0	1141.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
MMS3_k127_4016224_24	1267535.KB906767_gene1832	1.667e-53	210.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria,2JIUC@204432|Acidobacteriia	204432|Acidobacteriia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	-	-	-	-	-	-	-	-	-	IMS
MMS3_k127_4016224_34	234267.Acid_7037	6.889e-30	129.0	COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria	57723|Acidobacteria	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
MMS3_k127_4016224_13	234267.Acid_2167	6.058e-114	381.0	COG0477@1|root,COG2814@2|Bacteria,3Y47I@57723|Acidobacteria	57723|Acidobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_4016224_17	357808.RoseRS_2494	1.252e-82	290.0	COG0517@1|root,COG1993@1|root,COG0517@2|Bacteria,COG1993@2|Bacteria,2G69Z@200795|Chloroflexi,376P4@32061|Chloroflexia	32061|Chloroflexia	T	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF190
MMS3_k127_4016224_38	886293.Sinac_4609	1.995e-23	109.0	COG0640@1|root,COG0640@2|Bacteria,2J12M@203682|Planctomycetes	203682|Planctomycetes	K	transcriptional regulator, ArsR family protein	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
MMS3_k127_4016224_12	1267533.KB906734_gene3758	2.888e-117	382.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria	57723|Acidobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
MMS3_k127_4016224_3	886293.Sinac_4362	7.899e-155	501.0	COG0798@1|root,COG0798@2|Bacteria,2IY8H@203682|Planctomycetes	203682|Planctomycetes	P	COG0798 Arsenite efflux pump ACR3 and related	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
MMS3_k127_4016224_25	1242864.D187_001222	4.821e-53	190.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2YUZQ@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
MMS3_k127_4016224_26	886293.Sinac_2660	2.542e-51	190.0	COG0639@1|root,COG0639@2|Bacteria,2IYXT@203682|Planctomycetes	203682|Planctomycetes	T	TIGRFAM phosphoesterase, MJ0936 family	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_4016224_28	243233.MCA1193	4.676e-46	187.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,1RSJC@1236|Gammaproteobacteria,1XEMK@135618|Methylococcales	135618|Methylococcales	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
MMS3_k127_4016224_8	456442.Mboo_0933	4.817e-126	428.0	COG0218@1|root,arCOG00355@2157|Archaea	2157|Archaea	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
MMS3_k127_4016224_35	1382359.JIAL01000001_gene3030	2.886e-29	123.0	COG0239@1|root,COG0239@2|Bacteria,3Y54A@57723|Acidobacteria,2JJPV@204432|Acidobacteriia	204432|Acidobacteriia	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
MMS3_k127_4016224_19	479434.Sthe_1782	9.749e-75	276.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	yidR	GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046397,GO:0071704,GO:0072329,GO:1901575	-	-	-	-	-	-	-	-	-	-	DPPIV_N,DUF3748,PD40,Peptidase_S9
MMS3_k127_4016224_20	330214.NIDE0858	1.781e-73	256.0	COG0745@1|root,COG0745@2|Bacteria,3J0JU@40117|Nitrospirae	40117|Nitrospirae	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_4016224_16	398767.Glov_0589	3.564e-90	319.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
MMS3_k127_4016224_7	395961.Cyan7425_4763	2.552e-130	448.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria,3KGQF@43988|Cyanothece	1117|Cyanobacteria	F	Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_4016224_43	314345.SPV1_07114	0.0002258	54.0	2DIWG@1|root,3049N@2|Bacteria,1R88E@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
MMS3_k127_4016224_2	240015.ACP_2552	2.872e-155	503.0	COG0226@1|root,COG0226@2|Bacteria,3Y399@57723|Acidobacteria,2JIVU@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the PstS family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMS3_k127_415655_0	234267.Acid_7252	1.402e-259	837.0	COG4447@1|root,COG4447@2|Bacteria,3Y69Z@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_415655_1	204669.Acid345_3094	1.899e-184	590.0	COG0477@1|root,COG2814@2|Bacteria,3Y2YV@57723|Acidobacteria,2JHJD@204432|Acidobacteriia	204432|Acidobacteriia	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
MMS3_k127_415655_2	861299.J421_6102	3.033e-54	196.0	COG2382@1|root,COG2382@2|Bacteria,1ZUJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
MMS3_k127_4158564_6	234267.Acid_5181	3.403e-243	769.0	COG0532@1|root,COG3266@1|root,COG0532@2|Bacteria,COG3266@2|Bacteria,3Y3UG@57723|Acidobacteria	57723|Acidobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
MMS3_k127_4158564_115	234267.Acid_5182	1.188e-18	88.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
MMS3_k127_4158564_106	1033734.CAET01000016_gene4195	1.15e-25	112.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,1ZGB3@1386|Bacillus	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
MMS3_k127_4158564_64	204669.Acid345_4214	4.656e-63	230.0	COG0618@1|root,COG0618@2|Bacteria,3Y2GZ@57723|Acidobacteria,2JI0W@204432|Acidobacteriia	204432|Acidobacteriia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
MMS3_k127_4158564_63	234267.Acid_6299	1.543e-63	229.0	COG0130@1|root,COG0130@2|Bacteria,3Y3PG@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
MMS3_k127_4158564_97	1242864.D187_006281	3.097e-35	137.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
MMS3_k127_4158564_4	204669.Acid345_1995	1.488e-273	863.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
MMS3_k127_4158564_46	204669.Acid345_0572	2.048e-83	291.0	COG0501@1|root,COG0501@2|Bacteria,3Y2PP@57723|Acidobacteria,2JI24@204432|Acidobacteriia	2|Bacteria	O	Peptidase M48	agmM	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
MMS3_k127_4158564_121	471854.Dfer_1128	3.083e-11	74.0	COG3595@1|root,COG3595@2|Bacteria,4NGRU@976|Bacteroidetes,47MSM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
MMS3_k127_4158564_21	1267533.KB906736_gene987	5.848e-151	523.0	COG1196@1|root,COG1196@2|Bacteria,3Y2W1@57723|Acidobacteria,2JHJF@204432|Acidobacteriia	204432|Acidobacteriia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
MMS3_k127_4158564_36	1198114.AciX9_1119	1.832e-111	381.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
MMS3_k127_4158564_119	573370.DMR_22380	2.671e-14	77.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,2MDCV@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_4158564_71	690850.Desaf_3235	5.583e-58	211.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2M9RT@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
MMS3_k127_4158564_113	926549.KI421517_gene1589	1.13e-19	104.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47X9U@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
MMS3_k127_4158564_10	555079.Toce_1246	7.868e-202	641.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,42FHT@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
MMS3_k127_4158564_24	204669.Acid345_2250	4.251e-144	473.0	COG0029@1|root,COG0029@2|Bacteria,3Y39F@57723|Acidobacteria,2JHJ5@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_4158564_41	1121430.JMLG01000021_gene1379	1.731e-93	319.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
MMS3_k127_4158564_27	204669.Acid345_1588	3.174e-133	439.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JKV3@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_4158564_75	204669.Acid345_1590	2.997e-53	204.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07708	ko02020,map02020	M00497,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,RsbRD_N
MMS3_k127_4158564_56	338966.Ppro_0982	1.079e-69	245.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
MMS3_k127_4158564_90	204669.Acid345_1573	4.752e-43	170.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_1573|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4158564_79	330214.NIDE3434	6.762e-52	205.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_4158564_43	330214.NIDE3435	6.588e-86	294.0	COG1131@1|root,COG1131@2|Bacteria,3J122@40117|Nitrospirae	40117|Nitrospirae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_4158564_108	204669.Acid345_0799	4.486e-23	112.0	COG0607@1|root,COG1651@1|root,COG3266@1|root,COG4243@1|root,COG0607@2|Bacteria,COG1651@2|Bacteria,COG3266@2|Bacteria,COG4243@2|Bacteria,3Y5CK@57723|Acidobacteria,2JJU9@204432|Acidobacteriia	204432|Acidobacteriia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
MMS3_k127_4158564_112	204669.Acid345_1569	5.728e-20	96.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
MMS3_k127_4158564_22	1499967.BAYZ01000027_gene1786	2.291e-149	489.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_4158564_51	330214.NIDE0778	3.47e-78	293.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
MMS3_k127_4158564_28	1121920.AUAU01000016_gene1337	1.377e-129	425.0	COG1459@1|root,COG1459@2|Bacteria,3Y48Z@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
MMS3_k127_4158564_15	204669.Acid345_1391	3.857e-165	526.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMS3_k127_4158564_7	903818.KI912268_gene3150	5e-222	702.0	COG2804@1|root,COG2804@2|Bacteria,3Y2IS@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
MMS3_k127_4158564_130	1379698.RBG1_1C00001G0462	2.533e-05	56.0	COG2067@1|root,COG2067@2|Bacteria,2NPVZ@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4158564_45	204669.Acid345_1944	3.947e-84	283.0	COG1945@1|root,COG1945@2|Bacteria,3Y3KR@57723|Acidobacteria,2JIBD@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	-	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
MMS3_k127_4158564_124	234267.Acid_1121	4.012e-10	70.0	2BRBT@1|root,32KAC@2|Bacteria,3Y4U0@57723|Acidobacteria	57723|Acidobacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
MMS3_k127_4158564_55	1379698.RBG1_1C00001G1364	1.412e-71	259.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
MMS3_k127_4158564_49	861299.J421_1415	1.164e-79	286.0	COG0577@1|root,COG0577@2|Bacteria,1ZUG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_4158564_47	1047013.AQSP01000140_gene2536	3.465e-81	286.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_4158564_8	1267534.KB906757_gene1155	4.116e-220	703.0	COG0480@1|root,COG0480@2|Bacteria,3Y2RR@57723|Acidobacteria,2JI85@204432|Acidobacteriia	204432|Acidobacteriia	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_4158564_128	682795.AciX8_0200	1.825e-07	62.0	2BRBT@1|root,32KAC@2|Bacteria,3Y4U0@57723|Acidobacteria,2JJJP@204432|Acidobacteriia	204432|Acidobacteriia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
MMS3_k127_4158564_95	1054213.HMPREF9946_00493	2.647e-35	144.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,2JS6K@204441|Rhodospirillales	204441|Rhodospirillales	J	structural constituent of ribosome	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
MMS3_k127_4158564_23	204669.Acid345_1255	3.045e-146	473.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
MMS3_k127_4158564_48	562970.Btus_0181	1.041e-80	273.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,2782H@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
MMS3_k127_4158564_80	204669.Acid345_1252	8.666e-52	186.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria,2JJ4Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
MMS3_k127_4158564_85	411459.RUMOBE_02841	5.21e-48	175.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3Y043@572511|Blautia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
MMS3_k127_4158564_120	880072.Desac_1432	4.093e-14	72.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
MMS3_k127_4158564_117	644968.DFW101_0740	3.436e-15	78.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MCF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
MMS3_k127_4158564_38	1120973.AQXL01000112_gene1094	1.214e-100	346.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMS3_k127_4158564_69	589924.Ferp_1104	2.73e-59	214.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMS3_k127_4158564_13	1047013.AQSP01000074_gene1894	2.626e-191	608.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
MMS3_k127_4158564_91	1042163.BRLA_c001980	8.664e-43	162.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,26WST@186822|Paenibacillaceae	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
MMS3_k127_4158564_118	62928.azo3399	7.679e-15	76.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,2KX85@206389|Rhodocyclales	206389|Rhodocyclales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
MMS3_k127_4158564_66	1121423.JONT01000027_gene642	1.487e-62	219.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,261HV@186807|Peptococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
MMS3_k127_4158564_93	644966.Tmar_2279	1.808e-39	150.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3WCK3@538999|Clostridiales incertae sedis	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
MMS3_k127_4158564_73	909663.KI867150_gene2599	6.559e-55	198.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2WN9B@28221|Deltaproteobacteria,2MRVX@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
MMS3_k127_4158564_89	1340493.JNIF01000003_gene3221	1.827e-44	165.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
MMS3_k127_4158564_110	1340493.JNIF01000003_gene3220	4.544e-21	95.0	COG0199@1|root,COG0199@2|Bacteria,3Y5HM@57723|Acidobacteria	57723|Acidobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
MMS3_k127_4158564_53	1382306.JNIM01000001_gene3537	6.736e-75	261.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi	200795|Chloroflexi	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
MMS3_k127_4158564_98	644966.Tmar_2284	3.978e-33	141.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3WCKT@538999|Clostridiales incertae sedis	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
MMS3_k127_4158564_74	240015.ACP_1441	1.597e-53	190.0	COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria,2JJ86@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
MMS3_k127_4158564_109	2325.TKV_c20480	4.121e-21	98.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,42GX3@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
MMS3_k127_4158564_129	1504319.GM45_2610	2.584e-06	54.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,3UWTS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
MMS3_k127_4158564_60	240015.ACP_1444	4.808e-65	225.0	COG0197@1|root,COG0197@2|Bacteria,3Y4EG@57723|Acidobacteria,2JJ2G@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
MMS3_k127_4158564_42	204669.Acid345_1232	1.325e-92	314.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria,2JIRU@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
MMS3_k127_4158564_105	278963.ATWD01000001_gene1835	2.813e-26	119.0	COG0091@1|root,COG0091@2|Bacteria,3Y4KH@57723|Acidobacteria,2JJ8K@204432|Acidobacteriia	204432|Acidobacteriia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
MMS3_k127_4158564_94	1304284.L21TH_0896	8.392e-39	148.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,36JHK@31979|Clostridiaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
MMS3_k127_4158564_30	335543.Sfum_1558	2.874e-123	401.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2MR4Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
MMS3_k127_4158564_104	278963.ATWD01000001_gene1838	6.703e-27	112.0	COG0089@1|root,COG0089@2|Bacteria,3Y58W@57723|Acidobacteria,2JJR2@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
MMS3_k127_4158564_82	639030.JHVA01000001_gene1553	4.116e-51	188.0	COG0088@1|root,COG0088@2|Bacteria,3Y2PM@57723|Acidobacteria,2JHVM@204432|Acidobacteriia	204432|Acidobacteriia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
MMS3_k127_4158564_54	234267.Acid_5118	2.53e-73	254.0	COG0087@1|root,COG0087@2|Bacteria,3Y2H7@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
MMS3_k127_4158564_81	204669.Acid345_1225	1.42e-51	184.0	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria,2JJAS@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
MMS3_k127_4158564_3	243231.GSU2860	6.4e-323	1003.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_4158564_62	1089553.Tph_c25890	4.83e-64	222.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,42G2K@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
MMS3_k127_4158564_67	404589.Anae109_1907	1.92e-62	221.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,2YV8E@29|Myxococcales	28221|Deltaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
MMS3_k127_4158564_59	379066.GAU_1288	1.018e-66	238.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_4158564_70	385682.AFSL01000073_gene1408	1.04e-58	227.0	COG0642@1|root,COG2205@2|Bacteria,4P0P0@976|Bacteroidetes,2FMBM@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
MMS3_k127_4158564_44	1267534.KB906755_gene4691	2.885e-85	287.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_4158564_2	1234364.AMSF01000079_gene1847	0.0	1222.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_4158564_37	1095769.CAHF01000011_gene2301	3.528e-107	368.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
MMS3_k127_4158564_33	365044.Pnap_3246	1.007e-120	395.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VJHU@28216|Betaproteobacteria,4A9S6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMS3_k127_4158564_16	62928.azo2862	8.782e-165	524.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,2KW6R@206389|Rhodocyclales	206389|Rhodocyclales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
MMS3_k127_4158564_52	543728.Vapar_1244	1.46e-76	270.0	COG0265@1|root,COG0265@2|Bacteria,1QWA4@1224|Proteobacteria,2VK6X@28216|Betaproteobacteria,4A9X2@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
MMS3_k127_4158564_12	639030.JHVA01000001_gene592	5.328e-194	616.0	COG0591@1|root,COG0591@2|Bacteria,3Y3RT@57723|Acidobacteria,2JHK6@204432|Acidobacteriia	2|Bacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yhjB	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
MMS3_k127_4158564_5	1120919.AUBI01000010_gene134	2.822e-260	816.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2U29S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase domain protein	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_4158564_1	671143.DAMO_0533	0.0	1830.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMS3_k127_4158564_0	204669.Acid345_4676	0.0	2052.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria,2JIQM@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
MMS3_k127_4158564_92	580327.Tthe_0423	2.49e-41	155.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,42GKP@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
MMS3_k127_4158564_103	278963.ATWD01000001_gene1493	1.805e-27	124.0	COG0244@1|root,COG0244@2|Bacteria,3Y4N2@57723|Acidobacteria,2JJ81@204432|Acidobacteriia	204432|Acidobacteriia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
MMS3_k127_4158564_40	903818.KI912268_gene2416	2.559e-94	314.0	COG0081@1|root,COG0081@2|Bacteria,3Y2HX@57723|Acidobacteria	57723|Acidobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
MMS3_k127_4158564_72	1499967.BAYZ01000113_gene2935	5.585e-58	204.0	COG0080@1|root,COG0080@2|Bacteria,2NP7W@2323|unclassified Bacteria	2|Bacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
MMS3_k127_4158564_57	1047013.AQSP01000086_gene2011	7.987e-69	244.0	COG0250@1|root,COG0250@2|Bacteria,2NPAP@2323|unclassified Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
MMS3_k127_4158564_123	1150626.PHAMO_320002	3.288e-10	66.0	COG0690@1|root,COG0690@2|Bacteria,1N75P@1224|Proteobacteria,2UF51@28211|Alphaproteobacteria,2JTWP@204441|Rhodospirillales	204441|Rhodospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
MMS3_k127_4158564_114	880072.Desac_1470	2.09e-19	87.0	COG0267@1|root,COG0267@2|Bacteria,1NJ67@1224|Proteobacteria,42V5X@68525|delta/epsilon subdivisions,2WSIR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
MMS3_k127_4158564_9	861299.J421_2772	8.113e-203	639.0	COG0050@1|root,COG0050@2|Bacteria,1ZSZD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMS3_k127_4158564_77	243230.DR_0748	3.58e-52	192.0	COG0566@1|root,COG0566@2|Bacteria,1WIZZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
MMS3_k127_4158564_26	1121428.DESHY_150015___1	2.24e-140	462.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,26070@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMS3_k127_4158564_39	401526.TcarDRAFT_0127	3.218e-98	334.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,4H2VG@909932|Negativicutes	909932|Negativicutes	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
MMS3_k127_4158564_100	880073.Calab_1964	2.623e-29	126.0	COG3382@1|root,COG3382@2|Bacteria,2NPUN@2323|unclassified Bacteria	2|Bacteria	S	B3/4 domain	XK27_07210	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4
MMS3_k127_4158564_87	204669.Acid345_0120	5.399e-47	181.0	COG0204@1|root,COG0204@2|Bacteria,3Y4EM@57723|Acidobacteria,2JJ6E@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS3_k127_4158564_34	204669.Acid345_0189	4.681e-114	379.0	COG4956@1|root,COG4956@2|Bacteria,3Y2RT@57723|Acidobacteria,2JKNZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
MMS3_k127_4158564_18	330214.NIDE1676	4.243e-158	512.0	COG1066@1|root,COG1066@2|Bacteria,3J0BP@40117|Nitrospirae	40117|Nitrospirae	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI,Lon_C
MMS3_k127_4158564_50	338963.Pcar_2234	1.356e-79	279.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,43TGR@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
MMS3_k127_4158564_20	574087.Acear_2325	1.681e-152	496.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WANE@53433|Halanaerobiales	186801|Clostridia	L	Replicative DNA helicase	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
MMS3_k127_4158564_88	1382359.JIAL01000001_gene1373	6.277e-46	172.0	COG0359@1|root,COG0359@2|Bacteria,3Y4MD@57723|Acidobacteria,2JJAN@204432|Acidobacteriia	204432|Acidobacteriia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
MMS3_k127_4158564_107	177439.DP2596	3.154e-24	106.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria,2MKM0@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
MMS3_k127_4158564_111	1340493.JNIF01000004_gene998	6.63e-21	98.0	COG0360@1|root,COG0360@2|Bacteria,3Y50N@57723|Acidobacteria	57723|Acidobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
MMS3_k127_4158564_76	498761.HM1_0724	3.528e-53	194.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
MMS3_k127_4158564_84	1267535.KB906767_gene747	4.116e-50	186.0	COG1825@1|root,COG1825@2|Bacteria,3Y41C@57723|Acidobacteria,2JHW5@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
MMS3_k127_4158564_29	1267535.KB906767_gene748	1.806e-127	415.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria,2JHTF@204432|Acidobacteriia	204432|Acidobacteriia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
MMS3_k127_4158564_83	702437.HMPREF9432_01113	5.457e-51	192.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4H1VY@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
MMS3_k127_4158564_58	204669.Acid345_4603	5.024e-68	256.0	COG0457@1|root,COG0457@2|Bacteria,3Y35N@57723|Acidobacteria,2JHIM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
MMS3_k127_4158564_116	1047013.AQSP01000138_gene1048	3.6e-16	93.0	COG2835@1|root,COG2835@2|Bacteria,2NQ60@2323|unclassified Bacteria	2|Bacteria	S	Trm112p-like protein	ycaR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.7.1.130	ko:K00912,ko:K09791	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Trm112p
MMS3_k127_4158564_86	1047013.AQSP01000138_gene1047	2.221e-47	185.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMS3_k127_4158564_65	1047013.AQSP01000138_gene1046	8.476e-63	231.0	COG3307@1|root,COG3307@2|Bacteria,2NQ25@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
MMS3_k127_4158564_68	330214.NIDE2553	2.695e-62	242.0	COG2870@1|root,COG2870@2|Bacteria,3J0GT@40117|Nitrospirae	40117|Nitrospirae	M	Phosphomethylpyrimidine kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
MMS3_k127_4158564_19	671143.DAMO_1629	4.048e-155	511.0	COG0138@1|root,COG0138@2|Bacteria,2NNQ2@2323|unclassified Bacteria	2|Bacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcHS_1320.EcHS_A4240,iPC815.YPO3728	AICARFT_IMPCHas,MGS
MMS3_k127_4158564_101	671143.DAMO_0140	2.863e-28	115.0	COG1278@1|root,COG1278@2|Bacteria,2NPXP@2323|unclassified Bacteria	2|Bacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_4158564_127	404589.Anae109_0016	1.411e-08	66.0	COG3266@1|root,COG3266@2|Bacteria,1N9VA@1224|Proteobacteria,42VXQ@68525|delta/epsilon subdivisions,2WSBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4158564_31	1382306.JNIM01000001_gene83	1.538e-122	409.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
MMS3_k127_4158564_61	234267.Acid_4729	5.239e-65	234.0	COG0457@1|root,COG0457@2|Bacteria,3Y7Q5@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
MMS3_k127_4158564_78	164757.Mjls_0908	5.156e-52	195.0	COG0317@1|root,COG0317@2|Bacteria,2IC8P@201174|Actinobacteria,234D0@1762|Mycobacteriaceae	201174|Actinobacteria	KT	HD domain	spoT	-	-	-	-	-	-	-	-	-	-	-	HD_4
MMS3_k127_4158564_32	671143.DAMO_2690	2.047e-122	412.0	COG1007@1|root,COG1007@2|Bacteria,2NNMY@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMS3_k127_4158564_14	1125863.JAFN01000001_gene2409	2.086e-178	578.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
MMS3_k127_4158564_11	247490.KSU1_D0317	5.933e-199	646.0	COG1009@1|root,COG1009@2|Bacteria,2IX10@203682|Planctomycetes	203682|Planctomycetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
MMS3_k127_4158564_102	316067.Geob_0472	1.431e-27	123.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMS3_k127_4158564_99	1185876.BN8_06303	7.738e-30	125.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,47PS7@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
MMS3_k127_4158564_35	671143.DAMO_2695	1.699e-112	372.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
MMS3_k127_4158564_17	1223523.H340_08188	4.768e-160	516.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMS3_k127_4158564_96	1521187.JPIM01000094_gene1031	2.9e-35	153.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi,375IT@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMS3_k127_4158564_25	671143.DAMO_2698	3.954e-142	461.0	COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
MMS3_k127_4158564_125	748658.KB907316_gene523	1.003e-09	61.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1WYIT@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
MMS3_k127_4166768_2	398767.Glov_0004	2.074e-230	731.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMS3_k127_4166768_0	330214.NIDE0004	5.695e-320	1010.0	COG0188@1|root,COG0188@2|Bacteria,3J0EH@40117|Nitrospirae	40117|Nitrospirae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMS3_k127_4166768_3	1089553.Tph_c08890	1.981e-189	617.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,42EUR@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
MMS3_k127_4166768_1	1267535.KB906767_gene2550	7.595e-258	807.0	COG0449@1|root,COG0449@2|Bacteria,3Y2NE@57723|Acidobacteria,2JI69@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
MMS3_k127_4166768_4	671143.DAMO_1990	4.258e-131	433.0	COG1207@1|root,COG1207@2|Bacteria,2NNPC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528,ko:K16203	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000,ko01002	3.A.1.5.2	-	iJN678.glmU,iLJ478.TM1629	Hexapep,NTP_transf_3,NTP_transferase
MMS3_k127_4166768_5	1026882.MAMP_02673	0.0004218	51.0	COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,1RXYT@1236|Gammaproteobacteria,45ZNX@72273|Thiotrichales	72273|Thiotrichales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
MMS3_k127_4202387_5	580332.Slit_1871	5.734e-64	224.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
MMS3_k127_4202387_8	240015.ACP_0684	8.843e-41	157.0	COG2020@1|root,COG2020@2|Bacteria,3Y55R@57723|Acidobacteria,2JJVJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	PEMT
MMS3_k127_4202387_1	861299.J421_0392	1.513e-98	337.0	COG1301@1|root,COG1301@2|Bacteria,1ZTDM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
MMS3_k127_4202387_3	1380386.JIAW01000004_gene365	8.519e-73	252.0	COG5588@1|root,COG5588@2|Bacteria,2HIPH@201174|Actinobacteria,235FA@1762|Mycobacteriaceae	2|Bacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
MMS3_k127_4202387_2	211165.AJLN01000116_gene3204	3.591e-75	259.0	COG5486@1|root,COG5486@2|Bacteria,1GF5E@1117|Cyanobacteria	1117|Cyanobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
MMS3_k127_4202387_4	1123399.AQVE01000015_gene1860	2.591e-71	262.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	ghrA	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
MMS3_k127_4202387_7	1227500.C494_10625	3.148e-45	170.0	COG4635@1|root,arCOG00524@2157|Archaea,2XWSS@28890|Euryarchaeota,23V70@183963|Halobacteria	183963|Halobacteria	C	COG4635 Flavodoxin	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
MMS3_k127_4202387_6	1121920.AUAU01000006_gene301	4.112e-52	190.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4202387_0	379066.GAU_2322	7.59e-180	570.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1ZSS1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
MMS3_k127_4236431_4	641491.DND132_0252	7.035e-75	271.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2M7ZK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMS3_k127_4236431_10	1382359.JIAL01000001_gene557	4.679e-06	59.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria,2JJ61@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_4236431_3	886293.Sinac_6888	7.509e-81	280.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
MMS3_k127_4236431_1	204669.Acid345_2220	7.07e-97	344.0	COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_4236431_5	478741.JAFS01000002_gene874	2.297e-68	241.0	COG0842@1|root,COG0842@2|Bacteria,46YUC@74201|Verrucomicrobia,37FVS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_4236431_6	234267.Acid_4378	2.604e-35	139.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
MMS3_k127_4236431_9	187272.Mlg_0156	6.026e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1WX0E@135613|Chromatiales	135613|Chromatiales	U	PEP-CTERM system TPR-repeat lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
MMS3_k127_4236431_2	1123242.JH636436_gene370	2.059e-87	316.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
MMS3_k127_4236431_0	1047013.AQSP01000123_gene1531	1.583e-121	417.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
MMS3_k127_4236431_7	234267.Acid_3898	2.633e-17	97.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
MMS3_k127_4236431_8	278963.ATWD01000001_gene4299	1.296e-11	78.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria,2JKG4@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4260263_9	289376.THEYE_A1784	1.301e-58	214.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	MGDG_synth,PHP
MMS3_k127_4260263_10	395964.KE386496_gene2461	1.876e-53	197.0	COG1216@1|root,COG1216@2|Bacteria,1QZYZ@1224|Proteobacteria,2TYGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_4260263_1	1267533.KB906739_gene2666	4.84e-240	763.0	COG4206@1|root,COG4206@2|Bacteria,3Y3DX@57723|Acidobacteria,2JI30@204432|Acidobacteriia	204432|Acidobacteriia	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_4260263_6	448385.sce9042	1.339e-75	261.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,1RDAY@1224|Proteobacteria,43CWS@68525|delta/epsilon subdivisions,2X84R@28221|Deltaproteobacteria,2YX1U@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
MMS3_k127_4260263_12	1121930.AQXG01000004_gene2901	7.015e-06	53.0	2DQCB@1|root,335WZ@2|Bacteria,4P8HC@976|Bacteroidetes	976|Bacteroidetes	S	Family of unknown function (DUF5335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5335
MMS3_k127_4260263_4	1254432.SCE1572_36810	2.979e-101	338.0	COG0462@1|root,COG0462@2|Bacteria,1RCRN@1224|Proteobacteria,42QPH@68525|delta/epsilon subdivisions,2WMQV@28221|Deltaproteobacteria,2YU6H@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
MMS3_k127_4260263_5	1123368.AUIS01000038_gene38	6.113e-79	269.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,2NCU9@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
MMS3_k127_4260263_0	1500897.JQNA01000002_gene1522	0.0	1083.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VNZQ@28216|Betaproteobacteria,1KGKU@119060|Burkholderiaceae	28216|Betaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMS3_k127_4260263_7	1313172.YM304_32080	1.593e-73	255.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
MMS3_k127_4260263_8	1379270.AUXF01000001_gene2281	1.688e-68	242.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
MMS3_k127_4260263_11	1384056.N787_04420	3.697e-28	127.0	28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria,1RY8I@1236|Gammaproteobacteria,1X6I4@135614|Xanthomonadales	135614|Xanthomonadales	M	S1/P1 Nuclease	-	-	3.1.30.1	ko:K05986	-	-	-	-	ko00000,ko01000	-	-	-	S1-P1_nuclease
MMS3_k127_4260263_2	926556.Echvi_0838	6.981e-218	715.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
MMS3_k127_4260263_3	1183438.GKIL_2776	3.232e-200	651.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
MMS3_k127_4260263_13	10116.ENSRNOP00000055994	9.933e-05	52.0	KOG4053@1|root,KOG4053@2759|Eukaryota,38CXR@33154|Opisthokonta,3BJY3@33208|Metazoa,3D0G3@33213|Bilateria,47YVR@7711|Chordata,48YV2@7742|Vertebrata,3J3Z4@40674|Mammalia,35MY8@314146|Euarchontoglires,4Q6XJ@9989|Rodentia	33208|Metazoa	K	Ataxin-1 and HBP1 module (AXH)	ATXN1L	GO:0000122,GO:0002682,GO:0002684,GO:0003008,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0006355,GO:0006357,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0008150,GO:0008284,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0019219,GO:0019222,GO:0030198,GO:0030323,GO:0030324,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0035176,GO:0035295,GO:0042127,GO:0043062,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045892,GO:0045934,GO:0048286,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0051094,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051703,GO:0051704,GO:0051705,GO:0060255,GO:0060322,GO:0060541,GO:0065007,GO:0070013,GO:0071840,GO:0072091,GO:0080090,GO:1902033,GO:1902035,GO:1902679,GO:1903506,GO:1903507,GO:1903706,GO:1903708,GO:2000026,GO:2000112,GO:2000113,GO:2000648,GO:2001141	-	-	-	-	-	-	-	-	-	-	AXH
MMS3_k127_46117_17	568706.BN118_0190	2.789e-35	148.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,3T1SQ@506|Alcaligenaceae	28216|Betaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
MMS3_k127_46117_18	667014.Thein_1627	1.514e-34	142.0	COG0852@1|root,COG0852@2|Bacteria,2GHXK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
MMS3_k127_46117_9	671143.DAMO_1605	1.596e-70	241.0	COG0377@1|root,COG0377@2|Bacteria,2NP84@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMS3_k127_46117_16	1232410.KI421424_gene1780	8.662e-40	153.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42UPV@68525|delta/epsilon subdivisions,2WQB6@28221|Deltaproteobacteria,43UXF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
MMS3_k127_46117_3	1047013.AQSP01000139_gene2322	1.251e-171	561.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
MMS3_k127_46117_4	204669.Acid345_3014	1.301e-124	426.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
MMS3_k127_46117_0	404589.Anae109_1724	0.0	1742.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YU11@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMS3_k127_46117_23	887929.HMP0721_1447	8.955e-06	55.0	2931F@1|root,2ZQIQ@2|Bacteria,1V5HB@1239|Firmicutes,24IEB@186801|Clostridia,25Z04@186806|Eubacteriaceae	186801|Clostridia	S	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_46117_19	882082.SaccyDRAFT_1692	2.573e-34	136.0	COG5637@1|root,COG5637@2|Bacteria,2I3U7@201174|Actinobacteria,4E5IY@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_46117_2	357808.RoseRS_4018	2.009e-252	801.0	COG0243@1|root,COG0243@2|Bacteria,2G7V5@200795|Chloroflexi,375JH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
MMS3_k127_46117_10	1169154.KB897782_gene4979	1.814e-69	245.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
MMS3_k127_46117_14	246197.MXAN_1552	2.337e-48	181.0	COG0784@1|root,COG0784@2|Bacteria,1N7IK@1224|Proteobacteria,42VBR@68525|delta/epsilon subdivisions,2WRA1@28221|Deltaproteobacteria,2Z0IT@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMS3_k127_46117_13	861299.J421_2925	4.021e-53	191.0	COG1666@1|root,COG1666@2|Bacteria,1ZTNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
MMS3_k127_46117_1	338966.Ppro_3267	1.719e-314	990.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,42MEW@68525|delta/epsilon subdivisions,2WJX1@28221|Deltaproteobacteria,43SW5@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Alpha amylase, catalytic domain	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
MMS3_k127_46117_6	575540.Isop_3482	3.138e-106	377.0	COG2204@1|root,COG2204@2|Bacteria,2IWYY@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_46117_8	234267.Acid_0345	1.26e-83	295.0	COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
MMS3_k127_46117_11	56780.SYN_01953	1.209e-62	222.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_46117_12	330214.NIDE1491	3.935e-53	196.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
MMS3_k127_46117_15	861299.J421_3266	1.263e-45	176.0	COG1427@1|root,COG1427@2|Bacteria,1ZT6H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
MMS3_k127_46117_20	517418.Ctha_1211	2.746e-15	83.0	COG1309@1|root,COG1309@2|Bacteria,1FF9F@1090|Chlorobi	1090|Chlorobi	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_46117_5	204669.Acid345_3096	1.881e-110	383.0	COG1538@1|root,COG1538@2|Bacteria,3Y3Y3@57723|Acidobacteria,2JID8@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMS3_k127_46117_7	1267535.KB906767_gene922	1.007e-100	344.0	COG1566@1|root,COG1566@2|Bacteria,3Y2GY@57723|Acidobacteria,2JIUM@204432|Acidobacteriia	204432|Acidobacteriia	V	Biotin-lipoyl like	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMS3_k127_46117_21	438753.AZC_2885	6.56e-08	61.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,3F0R0@335928|Xanthobacteraceae	28211|Alphaproteobacteria	U	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
MMS3_k127_462046_4	867903.ThesuDRAFT_01405	0.0008264	43.0	298S5@1|root,313VY@2|Bacteria,1U9KD@1239|Firmicutes,25702@186801|Clostridia	186801|Clostridia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
MMS3_k127_462046_3	666686.B1NLA3E_08395	1.817e-09	64.0	298S5@1|root,2ZVWF@2|Bacteria,1V8I3@1239|Firmicutes,4HHTT@91061|Bacilli,1ZH6F@1386|Bacillus	91061|Bacilli	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
MMS3_k127_462046_0	867903.ThesuDRAFT_01144	1.875e-96	323.0	COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,247XS@186801|Clostridia	186801|Clostridia	IQ	Dehydrogenase	ydaD	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_462046_2	118168.MC7420_6251	1.128e-42	174.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG2905@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2905@2|Bacteria,COG3706@2|Bacteria,1FZWU@1117|Cyanobacteria,1H8MG@1150|Oscillatoriales	1117|Cyanobacteria	T	GGDEF domain'	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE3,GAF,GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_4,PAS_9
MMS3_k127_462046_1	1340493.JNIF01000003_gene1468	1.443e-61	233.0	COG3481@1|root,COG3481@2|Bacteria,3Y38F@57723|Acidobacteria	57723|Acidobacteria	S	nucleic acid binding	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
MMS3_k127_485449_2	1047013.AQSP01000132_gene1707	1.432e-90	306.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	rfbB	-	3.6.3.38,3.6.3.40	ko:K01990,ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
MMS3_k127_485449_4	1047013.AQSP01000132_gene1706	1.394e-73	256.0	COG1682@1|root,COG1682@2|Bacteria,2NQ2H@2323|unclassified Bacteria	2|Bacteria	U	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
MMS3_k127_485449_5	204669.Acid345_4331	1.766e-33	133.0	COG0355@1|root,COG0355@2|Bacteria,3Y515@57723|Acidobacteria,2JJJV@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
MMS3_k127_485449_1	330214.NIDE0372	6.938e-225	705.0	COG0055@1|root,COG0055@2|Bacteria,3J0BN@40117|Nitrospirae	40117|Nitrospirae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
MMS3_k127_485449_3	234267.Acid_0464	5.722e-89	301.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
MMS3_k127_485449_0	671143.DAMO_2962	6.855e-232	728.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
MMS3_k127_485449_6	589865.DaAHT2_1899	1.581e-21	105.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,2MJKI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
MMS3_k127_485449_7	1047013.AQSP01000132_gene1699	4.675e-09	66.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109,ko:K18682	ko00190,ko00195,ko01100,ko03018,map00190,map00195,map01100,map03018	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000,ko03019	3.A.2.1	-	-	ATP-synt_B
MMS3_k127_485449_8	1125863.JAFN01000001_gene2676	2.803e-07	58.0	COG0711@1|root,COG0711@2|Bacteria,1NA9K@1224|Proteobacteria,42VN2@68525|delta/epsilon subdivisions,2WR8C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpX	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
MMS3_k127_565420_3	1382359.JIAL01000001_gene2460	8.077e-157	509.0	COG1680@1|root,COG1680@2|Bacteria,3Y3DY@57723|Acidobacteria,2JHVC@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_565420_1	1122604.JONR01000037_gene4274	1.376e-176	561.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1X34W@135614|Xanthomonadales	135614|Xanthomonadales	C	NADP transhydrogenase	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
MMS3_k127_565420_6	1415780.JPOG01000001_gene3243	1.574e-39	155.0	COG3288@1|root,COG3288@2|Bacteria,1N0TD@1224|Proteobacteria,1SA8D@1236|Gammaproteobacteria,1XCEC@135614|Xanthomonadales	135614|Xanthomonadales	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
MMS3_k127_565420_0	1122604.JONR01000037_gene4272	6.931e-212	669.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,1X32D@135614|Xanthomonadales	135614|Xanthomonadales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
MMS3_k127_565420_4	1379698.RBG1_1C00001G0798	7.459e-135	461.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
MMS3_k127_565420_5	479434.Sthe_2734	1.145e-48	181.0	COG5516@1|root,COG5516@2|Bacteria,2G7GV@200795|Chloroflexi	200795|Chloroflexi	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
MMS3_k127_565420_2	448385.sce0906	1.13e-173	551.0	COG0122@1|root,COG0350@1|root,COG0122@2|Bacteria,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,43ARM@68525|delta/epsilon subdivisions,2X65K@28221|Deltaproteobacteria,2Z392@29|Myxococcales	28221|Deltaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,HhH-GPD
MMS3_k127_590240_8	272630.MexAM1_META1p3444	8.925e-47	171.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,1JUJ6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Class I peptide chain release factor	MA20_05665	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
MMS3_k127_590240_5	472759.Nhal_1354	2.542e-129	426.0	COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,1WYC3@135613|Chromatiales	135613|Chromatiales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMS3_k127_590240_7	497964.CfE428DRAFT_6620	1.072e-64	229.0	COG2360@1|root,COG2360@2|Bacteria,46VHR@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
MMS3_k127_590240_4	671143.DAMO_0850	1.306e-177	572.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
MMS3_k127_590240_9	204669.Acid345_0566	1.951e-21	107.0	COG0628@1|root,COG0628@2|Bacteria,3Y40R@57723|Acidobacteria,2JIX8@204432|Acidobacteriia	204432|Acidobacteriia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMS3_k127_590240_0	1123393.KB891326_gene91	0.0	1153.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria,1KS15@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Carbohydrate phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphorylase
MMS3_k127_590240_3	1123393.KB891326_gene87	3.828e-262	833.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_590240_1	1159870.KB907784_gene1816	0.0	1118.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VNZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase (P-type)	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMS3_k127_590240_6	876269.ARWA01000001_gene686	2.036e-97	340.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3NAFU@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	fixL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9
MMS3_k127_590240_2	1121104.AQXH01000001_gene2187	0.0	1099.0	COG4447@1|root,COG4447@2|Bacteria,4NK5F@976|Bacteroidetes,1IWI3@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_593970_4	479434.Sthe_3355	4.668e-88	300.0	COG2084@1|root,COG2084@2|Bacteria,2G6B3@200795|Chloroflexi,27Y9G@189775|Thermomicrobia	189775|Thermomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_593970_6	485913.Krac_2500	2.148e-50	194.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glycos_transf_2
MMS3_k127_593970_0	247490.KSU1_C0704	0.0	1241.0	COG0841@1|root,COG0841@2|Bacteria,2IY6W@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07788	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
MMS3_k127_593970_8	861299.J421_1312	4.247e-39	154.0	COG2318@1|root,COG2318@2|Bacteria,1ZV4R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_593970_1	1249627.D779_1480	3.271e-210	675.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RR0R@1236|Gammaproteobacteria,1WWF9@135613|Chromatiales	1236|Gammaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_593970_5	1047013.AQSP01000131_gene1841	1.37e-58	232.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_593970_9	234267.Acid_4938	8.716e-38	151.0	COG2043@1|root,COG2043@2|Bacteria,3Y6QC@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
MMS3_k127_593970_2	1121091.AUMP01000037_gene2934	2.822e-201	638.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli	91061|Bacilli	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
MMS3_k127_593970_3	518766.Rmar_2248	9.642e-102	357.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,4NDVH@976|Bacteroidetes,1FJQ2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	IrrE N-terminal-like domain	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_19,HTH_3,HTH_31,Peptidase_M78
MMS3_k127_593970_7	1047013.AQSP01000131_gene1841	1.629e-44	186.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_593970_10	639030.JHVA01000001_gene3190	1.002e-16	90.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria,2JKNG@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
MMS3_k127_600893_32	1267535.KB906767_gene66	2.106e-14	78.0	COG1008@1|root,COG1008@2|Bacteria,3Y3VX@57723|Acidobacteria	2|Bacteria	C	Proton-conducting membrane transporter	nuoM	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iSDY_1059.SDY_2473	Proton_antipo_M
MMS3_k127_600893_4	1267535.KB906767_gene65	4.123e-258	809.0	COG1009@1|root,COG1009@2|Bacteria,3Y2VS@57723|Acidobacteria,2JIG7@204432|Acidobacteriia	204432|Acidobacteriia	CP	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M,Proton_antipo_N
MMS3_k127_600893_30	1122603.ATVI01000005_gene3460	1.288e-33	134.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,1X6XC@135614|Xanthomonadales	135614|Xanthomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMS3_k127_600893_26	323261.Noc_1119	2.031e-50	187.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2280,iAF1260.b2280,iAPECO1_1312.APECO1_4285,iB21_1397.B21_02165,iBWG_1329.BWG_2054,iE2348C_1286.E2348C_2420,iEC042_1314.EC042_2521,iEC55989_1330.EC55989_2524,iECABU_c1320.ECABU_c26120,iECBD_1354.ECBD_1381,iECB_1328.ECB_02205,iECDH10B_1368.ECDH10B_2442,iECDH1ME8569_1439.ECDH1ME8569_2217,iECD_1391.ECD_02205,iECED1_1282.ECED1_2744,iECH74115_1262.ECH74115_3419,iECIAI1_1343.ECIAI1_2354,iECIAI39_1322.ECIAI39_2427,iECNA114_1301.ECNA114_2370,iECO103_1326.ECO103_2744,iECO111_1330.ECO111_3028,iECO26_1355.ECO26_3268,iECOK1_1307.ECOK1_2513,iECP_1309.ECP_2319,iECS88_1305.ECS88_2427,iECSE_1348.ECSE_2537,iECSF_1327.ECSF_2157,iECSP_1301.ECSP_3154,iECUMN_1333.ECUMN_2619,iECW_1372.ECW_m2468,iECs_1301.ECs3164,iEKO11_1354.EKO11_1487,iETEC_1333.ETEC_2415,iEcDH1_1363.EcDH1_1377,iEcE24377_1341.EcE24377A_2573,iEcHS_1320.EcHS_A2429,iEcSMS35_1347.EcSMS35_2434,iEcolC_1368.EcolC_1372,iJO1366.b2280,iJR904.b2280,iLF82_1304.LF82_1547,iNRG857_1313.NRG857_11545,iSBO_1134.SBO_2313,iSDY_1059.SDY_2476,iSFV_1184.SFV_2347,iSF_1195.SF2356,iSFxv_1172.SFxv_2600,iSSON_1240.SSON_2337,iS_1188.S2491,iSbBS512_1146.SbBS512_E2656,iUMN146_1321.UM146_05415,iUMNK88_1353.UMNK88_2830,iUTI89_1310.UTI89_C2560,iWFL_1372.ECW_m2468,iY75_1357.Y75_RS11955,iZ_1308.Z3539,ic_1306.c2821	Oxidored_q3
MMS3_k127_600893_18	1267535.KB906767_gene62	6.011e-93	306.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2281,iAF1260.b2281,iAPECO1_1312.APECO1_4284,iB21_1397.B21_02166,iBWG_1329.BWG_2055,iE2348C_1286.E2348C_2421,iEC042_1314.EC042_2522,iEC55989_1330.EC55989_2525,iECABU_c1320.ECABU_c26130,iECBD_1354.ECBD_1380,iECB_1328.ECB_02206,iECDH10B_1368.ECDH10B_2443,iECDH1ME8569_1439.ECDH1ME8569_2218,iECD_1391.ECD_02206,iECED1_1282.ECED1_2745,iECH74115_1262.ECH74115_3420,iECIAI1_1343.ECIAI1_2355,iECIAI39_1322.ECIAI39_2428,iECNA114_1301.ECNA114_2371,iECO103_1326.ECO103_2745,iECO111_1330.ECO111_3029,iECO26_1355.ECO26_3269,iECOK1_1307.ECOK1_2514,iECP_1309.ECP_2320,iECS88_1305.ECS88_2428,iECSE_1348.ECSE_2538,iECSF_1327.ECSF_2158,iECSP_1301.ECSP_3155,iECUMN_1333.ECUMN_2620,iECW_1372.ECW_m2469,iECs_1301.ECs3165,iEKO11_1354.EKO11_1486,iETEC_1333.ETEC_2416,iEcDH1_1363.EcDH1_1376,iEcE24377_1341.EcE24377A_2574,iEcHS_1320.EcHS_A2430,iEcSMS35_1347.EcSMS35_2435,iEcolC_1368.EcolC_1371,iG2583_1286.G2583_2818,iJO1366.b2281,iJR904.b2281,iLF82_1304.LF82_1546,iNRG857_1313.NRG857_11550,iPC815.YPO2548,iSBO_1134.SBO_2314,iSFV_1184.SFV_2348,iSF_1195.SF2357,iSFxv_1172.SFxv_2601,iS_1188.S2492,iSbBS512_1146.SbBS512_E2657,iUMN146_1321.UM146_05410,iUMNK88_1353.UMNK88_2831,iUTI89_1310.UTI89_C2561,iWFL_1372.ECW_m2469,iY75_1357.Y75_RS11960,iZ_1308.Z3540,ic_1306.c2822	Fer4
MMS3_k127_600893_13	1267535.KB906767_gene61	8.9e-156	506.0	COG1005@1|root,COG1005@2|Bacteria,3Y3VS@57723|Acidobacteria,2JHQZ@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
MMS3_k127_600893_1	1266925.JHVX01000004_gene1249	0.0	1079.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,373XN@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
MMS3_k127_600893_5	1267535.KB906767_gene59	2.458e-219	687.0	COG1894@1|root,COG1894@2|Bacteria,3Y2NM@57723|Acidobacteria,2JI09@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMS3_k127_600893_23	1123368.AUIS01000006_gene658	3.148e-68	236.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,2NCTW@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMS3_k127_600893_3	1267533.KB906747_gene22	2.537e-297	919.0	COG0649@1|root,COG0649@2|Bacteria,3Y3N1@57723|Acidobacteria,2JIDU@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
MMS3_k127_600893_17	1267535.KB906767_gene56	1.006e-103	340.0	COG0377@1|root,COG0377@2|Bacteria,3Y475@57723|Acidobacteria,2JHSW@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMS3_k127_600893_27	1267533.KB906747_gene24	2.627e-45	167.0	COG0838@1|root,COG0838@2|Bacteria	2|Bacteria	C	NADH dehydrogenase (ubiquinone) activity	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
MMS3_k127_600893_8	926549.KI421517_gene1063	5.25e-177	569.0	COG0362@1|root,COG0362@2|Bacteria,4NG05@976|Bacteroidetes,47NDJ@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
MMS3_k127_600893_7	478741.JAFS01000001_gene2094	1.531e-202	642.0	COG0364@1|root,COG0364@2|Bacteria,46SHX@74201|Verrucomicrobia,37G2K@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
MMS3_k127_600893_16	324925.Ppha_1915	3.675e-107	363.0	COG0282@1|root,COG0282@2|Bacteria,1FDWK@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
MMS3_k127_600893_25	886293.Sinac_2019	9.084e-55	196.0	COG0698@1|root,COG0698@2|Bacteria,2IZSB@203682|Planctomycetes	203682|Planctomycetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
MMS3_k127_600893_0	706587.Desti_2109	0.0	1095.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2MRG0@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
MMS3_k127_600893_12	266117.Rxyl_2380	2.513e-160	540.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CRW0@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_600893_6	562970.Btus_1268	1.014e-206	650.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,279DA@186823|Alicyclobacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249,ko:K18244	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_600893_11	479434.Sthe_1793	2.066e-167	534.0	COG1804@1|root,COG1804@2|Bacteria,2G61Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_600893_20	479434.Sthe_1792	1.466e-86	289.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
MMS3_k127_600893_22	933262.AXAM01000036_gene2178	2.736e-72	273.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,43B26@68525|delta/epsilon subdivisions,2X6G6@28221|Deltaproteobacteria,2MKC2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMS3_k127_600893_28	675635.Psed_4168	3.442e-43	169.0	COG2301@1|root,COG2301@2|Bacteria,2GN8S@201174|Actinobacteria,4EC6K@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
MMS3_k127_600893_29	443598.AUFA01000029_gene7048	4.626e-41	165.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TUEF@28211|Alphaproteobacteria,3JT5U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	MA20_15005	-	4.1.1.79	ko:K13039	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_600893_31	1038859.AXAU01000006_gene5613	4.877e-22	109.0	COG4032@1|root,COG4032@2|Bacteria,1P0HU@1224|Proteobacteria,2TRJ2@28211|Alphaproteobacteria,3JQMU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	MA20_16825	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
MMS3_k127_600893_14	326427.Cagg_3495	8.945e-156	504.0	COG1063@1|root,COG1063@2|Bacteria,2G8I2@200795|Chloroflexi,376PK@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
MMS3_k127_600893_2	1121918.ARWE01000001_gene3110	0.0	1031.0	COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria,42YST@68525|delta/epsilon subdivisions,2WURK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Glucodextranase, domain N	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_N,Glyco_hydro_15
MMS3_k127_600893_35	404589.Anae109_0870	0.0001362	52.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
MMS3_k127_600893_21	518766.Rmar_1472	1.791e-82	286.0	COG0491@1|root,COG0491@2|Bacteria,4NHXR@976|Bacteroidetes,1FJDJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
MMS3_k127_600893_9	321332.CYB_1248	2.395e-171	569.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1G1DF@1117|Cyanobacteria,1GZBH@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
MMS3_k127_600893_34	321332.CYB_1242	5.976e-13	77.0	COG2197@1|root,COG2197@2|Bacteria,1G5A4@1117|Cyanobacteria,1H1TX@1129|Synechococcus	1117|Cyanobacteria	K	TK COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
MMS3_k127_600893_15	1125863.JAFN01000001_gene1528	5.227e-142	467.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_600893_33	443143.GM18_0107	2.739e-14	81.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
MMS3_k127_600893_10	886293.Sinac_7544	5.828e-171	577.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2J4YH@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
MMS3_k127_600893_24	1210884.HG799465_gene11482	1.415e-65	230.0	COG0745@1|root,COG0745@2|Bacteria,2J0GS@203682|Planctomycetes	203682|Planctomycetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,Response_reg
MMS3_k127_600893_19	518766.Rmar_2028	5.713e-92	339.0	COG0457@1|root,COG3829@1|root,COG0457@2|Bacteria,COG3829@2|Bacteria,4PM5Y@976|Bacteroidetes,1FIME@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
MMS3_k127_633421_2	1128421.JAGA01000003_gene2925	9.821e-43	162.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_633421_1	682795.AciX8_3598	4.189e-73	271.0	COG3391@1|root,COG3391@2|Bacteria,3Y4CD@57723|Acidobacteria,2JJ1Y@204432|Acidobacteriia	204432|Acidobacteriia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_633421_0	378806.STAUR_0431	8.312e-137	451.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,43A0K@68525|delta/epsilon subdivisions,2X27T@28221|Deltaproteobacteria,2YXYR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_674692_2	511051.CSE_12980	2.797e-64	241.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
MMS3_k127_674692_1	1125863.JAFN01000001_gene1103	7.991e-65	226.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42RIQ@68525|delta/epsilon subdivisions,2WNC7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM PEBP family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
MMS3_k127_674692_3	279714.FuraDRAFT_0734	4.467e-14	84.0	COG0236@1|root,COG0236@2|Bacteria,1NHIC@1224|Proteobacteria,2VWCN@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
MMS3_k127_674692_0	1254432.SCE1572_36840	9.919e-125	412.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,42PEC@68525|delta/epsilon subdivisions,2X5JG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_679848_1	1379270.AUXF01000003_gene3552	1.116e-188	606.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060,Kelch_1,Kelch_6,Malectin,NPCBM
MMS3_k127_679848_6	237368.SCABRO_00902	1.258e-77	275.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
MMS3_k127_679848_0	1168059.KB899087_gene2407	6.435e-217	687.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,3EXZW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
MMS3_k127_679848_9	1068980.ARVW01000001_gene1733	3.328e-25	110.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
MMS3_k127_679848_10	1429916.X566_23310	3.328e-18	88.0	COG3290@1|root,COG3290@2|Bacteria,1QWJA@1224|Proteobacteria,2TWZ6@28211|Alphaproteobacteria,3K6Q0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_4
MMS3_k127_679848_11	1123248.KB893316_gene4609	5.997e-13	70.0	2EMYX@1|root,33FM2@2|Bacteria,4NY90@976|Bacteroidetes,1IZI6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_679848_5	285514.JNWO01000022_gene561	3.313e-80	277.0	COG0596@1|root,COG0596@2|Bacteria,2I26T@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the peptidase S33 family	pip	-	3.4.11.5,3.5.1.101	ko:K01259,ko:K18457	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_679848_3	234267.Acid_5333	6.734e-97	336.0	COG0154@1|root,COG0154@2|Bacteria,3Y6E5@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_679848_4	1499967.BAYZ01000009_gene5378	1.321e-91	312.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
MMS3_k127_679848_7	290397.Adeh_2530	2.144e-66	238.0	COG3118@1|root,COG3118@2|Bacteria,1QYGB@1224|Proteobacteria	1224|Proteobacteria	O	belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_679848_8	1191523.MROS_1542	6.883e-63	223.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
MMS3_k127_679848_2	1379270.AUXF01000002_gene1134	7.28e-125	435.0	COG2091@1|root,COG2091@2|Bacteria,1ZU9H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_680344_6	1047013.AQSP01000131_gene1841	7.662e-17	90.0	COG1629@1|root,COG4773@1|root,COG4771@2|Bacteria,COG4773@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_680344_3	240015.ACP_1580	2.321e-106	358.0	COG3391@1|root,COG3391@2|Bacteria,3Y4CD@57723|Acidobacteria,2JJ1Y@204432|Acidobacteriia	204432|Acidobacteriia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_680344_2	1297865.APJD01000005_gene3660	6.942e-107	356.0	COG5495@1|root,COG5495@2|Bacteria,1RDUW@1224|Proteobacteria,2VGE0@28211|Alphaproteobacteria,3JWCT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
MMS3_k127_680344_0	234267.Acid_5915	9.552e-176	558.0	COG0003@1|root,COG0071@1|root,COG0003@2|Bacteria,COG0071@2|Bacteria,3Y60Y@57723|Acidobacteria	57723|Acidobacteria	OP	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
MMS3_k127_680344_7	1345697.M493_06560	1.394e-07	63.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,1WFHX@129337|Geobacillus	91061|Bacilli	S	Domain of unknown function (DUF4115)	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
MMS3_k127_680344_8	1303692.SFUL_229	6.203e-05	56.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,Ricin_B_lectin,ThuA
MMS3_k127_680344_5	378806.STAUR_7741	8.557e-52	205.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,43DYN@68525|delta/epsilon subdivisions,2X924@28221|Deltaproteobacteria,2Z1I3@29|Myxococcales	28221|Deltaproteobacteria	M	Kelch	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
MMS3_k127_680344_4	1123258.AQXZ01000015_gene4497	3.426e-59	213.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_680344_1	56780.SYN_01995	6.271e-130	427.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_69353_1	765420.OSCT_1187	1.046e-110	373.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,376ZQ@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_69353_5	485913.Krac_6639	1.966e-39	163.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
MMS3_k127_69353_2	349161.Dred_2684	4.943e-89	312.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,26123@186807|Peptococcaceae	186801|Clostridia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
MMS3_k127_69353_8	96561.Dole_1616	2.572e-19	100.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria,2MKUK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
MMS3_k127_69353_6	1047013.AQSP01000139_gene2398	1.323e-37	161.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	lytC_1	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3,SLH
MMS3_k127_69353_7	272624.lpg0973	1.731e-30	131.0	COG3751@1|root,COG3751@2|Bacteria,1N2TX@1224|Proteobacteria,1SASI@1236|Gammaproteobacteria,1JE76@118969|Legionellales	118969|Legionellales	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
MMS3_k127_69353_9	1146883.BLASA_2248	2.126e-13	79.0	COG1266@1|root,COG1266@2|Bacteria,2IS6T@201174|Actinobacteria	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
MMS3_k127_69353_0	1121875.KB907549_gene2068	3.04e-321	1015.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_69353_4	1417296.U879_03685	1.236e-68	240.0	COG0500@1|root,COG2226@2|Bacteria,1R41W@1224|Proteobacteria,2UJDA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_69353_3	1417296.U879_03690	3.597e-72	252.0	COG1145@1|root,COG1456@1|root,COG1145@2|Bacteria,COG1456@2|Bacteria,1R6BH@1224|Proteobacteria,2USUR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD,Fer4
MMS3_k127_801332_11	489825.LYNGBM3L_63420	2.881e-219	704.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ,Thioesterase
MMS3_k127_801332_0	502025.Hoch_1748	0.0	1893.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2X86Z@28221|Deltaproteobacteria,2Z3ME@29|Myxococcales	28221|Deltaproteobacteria	Q	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
MMS3_k127_801332_1	358681.BBR47_28940	0.0	1821.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
MMS3_k127_801332_2	272134.KB731325_gene580	0.0	1687.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding,PilZ
MMS3_k127_801332_19	452637.Oter_1952	1.395e-19	100.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
MMS3_k127_801332_10	319003.Bra1253DRAFT_05989	1.401e-219	700.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,3JR7Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	symbiont process	nolO	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
MMS3_k127_801332_8	44060.JODL01000004_gene2603	2.103e-298	967.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,MFS_1,NAD_binding_4,PP-binding,Thioesterase
MMS3_k127_801332_6	272134.KB731325_gene578	0.0	1240.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HEH0@1150|Oscillatoriales	1117|Cyanobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
MMS3_k127_801332_13	402777.KB235898_gene5716	3.513e-104	386.0	COG0604@1|root,COG1020@1|root,COG0604@2|Bacteria,COG1020@2|Bacteria,1GBN8@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Condensation,Nitroreductase,PP-binding
MMS3_k127_801332_3	1265502.KB905942_gene2821	0.0	1370.0	COG3321@1|root,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,2VP69@28216|Betaproteobacteria,4AC3Q@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
MMS3_k127_801332_5	1469607.KK073768_gene3281	0.0	1318.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HJVE@1161|Nostocales	1117|Cyanobacteria	Q	COGs COG3321 Polyketide synthase modules and related protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
MMS3_k127_801332_4	452637.Oter_1969	0.0	1343.0	COG0604@1|root,COG1028@1|root,COG2227@1|root,COG3321@1|root,COG0604@2|Bacteria,COG1028@2|Bacteria,COG2227@2|Bacteria,COG3321@2|Bacteria,46TEY@74201|Verrucomicrobia	2|Bacteria	Q	short-chain dehydrogenase reductase SDR	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,PP-binding,PS-DH,TPR_8,Thioesterase,ketoacyl-synt
MMS3_k127_801332_9	1133850.SHJG_1662	1.73e-256	830.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
MMS3_k127_801332_15	483219.LILAB_29600	3.62e-63	236.0	COG3208@1|root,COG3208@2|Bacteria,1RGYT@1224|Proteobacteria,42X72@68525|delta/epsilon subdivisions,2WX12@28221|Deltaproteobacteria,2YV8S@29|Myxococcales	28221|Deltaproteobacteria	Q	thioesterase involved in non-ribosomal peptide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Thioesterase
MMS3_k127_801332_18	1254432.SCE1572_48210	2.817e-29	120.0	COG3251@1|root,COG3251@2|Bacteria,1PIM0@1224|Proteobacteria,43DZX@68525|delta/epsilon subdivisions,2WZAZ@28221|Deltaproteobacteria,2Z1R2@29|Myxococcales	28221|Deltaproteobacteria	S	MbtH-like protein	-	-	-	ko:K05375	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH
MMS3_k127_801332_16	118005.AWNK01000005_gene1470	1.881e-59	218.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMS3_k127_801332_12	349521.HCH_02804	1.094e-116	396.0	COG4615@1|root,COG4615@2|Bacteria,1MVIC@1224|Proteobacteria,1RMYK@1236|Gammaproteobacteria,1XI58@135619|Oceanospirillales	135619|Oceanospirillales	V	Cyclic peptide transporter	yojI	-	-	ko:K06159,ko:K06160	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.113.2,3.A.1.113.3	-	-	ABC_membrane,ABC_tran
MMS3_k127_801332_17	1254432.SCE1572_19025	2.289e-45	175.0	COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMS3_k127_801332_7	1267534.KB906754_gene3507	0.0	1052.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
MMS3_k127_801332_14	502025.Hoch_5835	9.649e-79	271.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,2YVWV@29|Myxococcales	28221|Deltaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
MMS3_k127_827344_0	234267.Acid_3778	2.738e-71	256.0	COG0577@1|root,COG0577@2|Bacteria,3Y3Z1@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
MMS3_k127_827344_4	1211115.ALIQ01000009_gene4302	3.333e-05	57.0	COG4927@1|root,COG4927@2|Bacteria,1NKHP@1224|Proteobacteria,2U18B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
MMS3_k127_827344_1	379066.GAU_3062	2.048e-26	127.0	COG1586@1|root,COG1586@2|Bacteria,1ZV1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
MMS3_k127_827344_3	246969.TAM4_922	1.1e-13	85.0	COG0500@1|root,arCOG01773@2157|Archaea,2Y7P0@28890|Euryarchaeota,245AH@183968|Thermococci	183968|Thermococci	Q	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_827344_2	1128421.JAGA01000002_gene387	8.903e-18	98.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_827344_5	146922.JOFU01000005_gene7036	0.0002788	53.0	COG3227@1|root,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	3.4.24.27	ko:K08603	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	FTP,He_PIG,Peptidase_M4,Peptidase_M4_C
MMS3_k127_828492_12	269799.Gmet_0923	1.475e-37	145.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,43UQ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
MMS3_k127_828492_6	1047013.AQSP01000111_gene1672	9.925e-73	261.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
MMS3_k127_828492_10	404589.Anae109_2577	1.73e-46	172.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
MMS3_k127_828492_8	926566.Terro_3991	2.742e-49	192.0	COG0859@1|root,COG0859@2|Bacteria,3Y3EJ@57723|Acidobacteria,2JIYJ@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMS3_k127_828492_13	240015.ACP_1605	2.547e-19	96.0	COG2020@1|root,COG2020@2|Bacteria,3Y4P4@57723|Acidobacteria,2JJBQ@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMS3_k127_828492_16	298386.PBPRB1578	1.178e-08	61.0	2DRWY@1|root,33DG4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_828492_4	765912.Thimo_0714	1.739e-83	284.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1WWYK@135613|Chromatiales	135613|Chromatiales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
MMS3_k127_828492_9	1095769.CAHF01000006_gene1693	5.387e-49	179.0	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,2VSYY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_828492_1	1123257.AUFV01000003_gene1004	1.415e-247	779.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RZ70@1236|Gammaproteobacteria,1X4ZJ@135614|Xanthomonadales	135614|Xanthomonadales	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61,TPR_3
MMS3_k127_828492_3	471852.Tcur_4402	2.299e-98	325.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4EFI4@85012|Streptosporangiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
MMS3_k127_828492_15	1123288.SOV_3c02750	6.939e-11	71.0	COG1196@1|root,COG1196@2|Bacteria,1UWW4@1239|Firmicutes,4H8PM@909932|Negativicutes	909932|Negativicutes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_828492_0	234267.Acid_3064	0.0	1424.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cu-oxidase_3,HYR,PAP2,PATR,P_proprotein,Peptidase_M14,Peptidase_M64,Peptidase_S8,SLH
MMS3_k127_828492_2	1267534.KB906754_gene3319	1.944e-186	593.0	COG0477@1|root,COG2814@2|Bacteria,3Y3ZZ@57723|Acidobacteria,2JKTQ@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_828492_11	404589.Anae109_2451	7.159e-41	167.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,2YVD8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
MMS3_k127_828492_5	1121861.KB899924_gene3502	5.304e-76	265.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2JRWE@204441|Rhodospirillales	204441|Rhodospirillales	H	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.408,1.1.1.409	ko:K22024	-	-	-	-	ko00000,ko01000	-	-	-	PdxA
MMS3_k127_828492_7	246194.CHY_0290	8.277e-52	187.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
MMS3_k127_846297_21	234267.Acid_6193	6.789e-07	51.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XD@57723|Acidobacteria	57723|Acidobacteria	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_846297_15	1382356.JQMP01000004_gene531	6.692e-51	205.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_846297_18	1499967.BAYZ01000096_gene4306	5.809e-16	93.0	COG3119@1|root,COG5652@1|root,COG3119@2|Bacteria,COG5652@2|Bacteria,2NRYS@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase,VanZ
MMS3_k127_846297_16	234267.Acid_4799	8.141e-51	187.0	COG2080@1|root,COG2080@2|Bacteria,3Y4U1@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_846297_6	1380394.JADL01000002_gene1729	5.381e-197	638.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2JUZD@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
MMS3_k127_846297_11	1382306.JNIM01000001_gene4028	9.639e-72	255.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
MMS3_k127_846297_1	234267.Acid_4270	0.0	1243.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_846297_22	402777.KB235906_gene310	4.676e-06	57.0	COG0615@1|root,COG1216@1|root,COG0615@2|Bacteria,COG1216@2|Bacteria,1G1YM@1117|Cyanobacteria,1HHMP@1150|Oscillatoriales	1117|Cyanobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
MMS3_k127_846297_8	1110502.TMO_0686	2.033e-118	385.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2TT2D@28211|Alphaproteobacteria,2JQKR@204441|Rhodospirillales	204441|Rhodospirillales	EH	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
MMS3_k127_846297_5	402881.Plav_3064	5.523e-199	640.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,1JN48@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Adenylylsulphate kinase	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
MMS3_k127_846297_2	379066.GAU_2380	3.026e-298	924.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1ZSZ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CE	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
MMS3_k127_846297_3	1379270.AUXF01000003_gene3544	1.532e-284	913.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1ZSVF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
MMS3_k127_846297_7	379066.GAU_2382	1.504e-164	532.0	COG1013@1|root,COG1013@2|Bacteria,1ZSWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_846297_4	1382359.JIAL01000001_gene1341	1.945e-258	822.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
MMS3_k127_846297_14	1121106.JQKB01000025_gene4086	2.27e-58	216.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2JTFN@204441|Rhodospirillales	204441|Rhodospirillales	O	SelR domain	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
MMS3_k127_846297_13	1122622.ATWJ01000007_gene2022	3.397e-59	218.0	COG0702@1|root,COG0702@2|Bacteria,2ICEY@201174|Actinobacteria,4FHR4@85021|Intrasporangiaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
MMS3_k127_846297_23	1121366.KB892467_gene1462	6.523e-06	58.0	COG1216@1|root,COG1216@2|Bacteria,2IMRN@201174|Actinobacteria,22KQE@1653|Corynebacteriaceae	201174|Actinobacteria	S	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
MMS3_k127_846297_19	710685.MycrhN_1766	9.838e-10	68.0	COG4122@1|root,COG4122@2|Bacteria,2HU21@201174|Actinobacteria,238TN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
MMS3_k127_846297_9	713586.KB900536_gene1541	9.703e-92	327.0	COG0463@1|root,COG0463@2|Bacteria,1P8G7@1224|Proteobacteria,1S2FE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4,Glycos_transf_2
MMS3_k127_846297_20	1198114.AciX9_2169	6.707e-07	57.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
MMS3_k127_846297_17	317936.Nos7107_1719	1.383e-31	134.0	2ERTE@1|root,33JCN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_846297_12	756067.MicvaDRAFT_4882	9.957e-69	246.0	COG2241@1|root,COG2241@2|Bacteria,1G2V3@1117|Cyanobacteria,1H9B7@1150|Oscillatoriales	1117|Cyanobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	-	-	-	-	-	-	-	-	-	-	TP_methylase
MMS3_k127_846297_10	1267534.KB906755_gene4316	1.985e-87	298.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_846297_0	234267.Acid_4623	0.0	1347.0	COG4447@1|root,COG4447@2|Bacteria,3Y2SN@57723|Acidobacteria	57723|Acidobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_929224_9	483219.LILAB_22110	1.736e-42	175.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
MMS3_k127_929224_8	240015.ACP_0840	6.116e-49	183.0	COG0668@1|root,COG0668@2|Bacteria,3Y9BD@57723|Acidobacteria,2JP5U@204432|Acidobacteriia	204432|Acidobacteriia	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
MMS3_k127_929224_6	330214.NIDE4207	6.12e-96	329.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
MMS3_k127_929224_1	1382359.JIAL01000001_gene2423	5.267e-308	949.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria	2|Bacteria	G	trehalose biosynthetic process	treS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576	2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16	ko:K00700,ko:K05343,ko:K16146	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01557,R02108,R02110,R02112,R09945,R11262	RC00002,RC00078,RC01816	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	APH,Alpha-amylase,Malt_amylase_C
MMS3_k127_929224_7	795797.C497_09098	7.902e-78	277.0	COG0477@1|root,arCOG00130@2157|Archaea,2XT83@28890|Euryarchaeota,23SW2@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_929224_5	1159870.KB907784_gene2897	6.902e-120	397.0	COG1994@1|root,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
MMS3_k127_929224_2	240015.ACP_0460	6.369e-161	525.0	COG0038@1|root,COG0038@2|Bacteria,3Y7TT@57723|Acidobacteria,2JMYW@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
MMS3_k127_929224_4	330214.NIDE0473	8.911e-141	455.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
MMS3_k127_929224_3	330214.NIDE0474	9.998e-143	464.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
MMS3_k127_929224_0	234267.Acid_1953	0.0	1170.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_966418_27	204669.Acid345_4591	1.164e-29	129.0	COG3595@1|root,COG3595@2|Bacteria,3Y8HC@57723|Acidobacteria,2JNF3@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
MMS3_k127_966418_22	292459.STH605	6.978e-61	229.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMS3_k127_966418_10	485913.Krac_7537	3.335e-115	386.0	COG1899@1|root,COG1899@2|Bacteria,2G9B5@200795|Chloroflexi	200795|Chloroflexi	O	Deoxyhypusine synthase	-	-	-	-	-	-	-	-	-	-	-	-	DS
MMS3_k127_966418_6	661478.OP10G_0980	1.841e-145	493.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HD,HD_5
MMS3_k127_966418_30	1394178.AWOO02000008_gene2879	2.112e-24	112.0	COG1018@1|root,COG1018@2|Bacteria,2I0Y9@201174|Actinobacteria,4EHIW@85012|Streptosporangiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
MMS3_k127_966418_38	1437882.AZRU01000031_gene66	3.641e-05	51.0	COG2823@1|root,COG2823@2|Bacteria,1RHX0@1224|Proteobacteria,1S742@1236|Gammaproteobacteria,1YIS5@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
MMS3_k127_966418_17	1382306.JNIM01000001_gene4148	3.866e-85	289.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi	200795|Chloroflexi	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_966418_37	234267.Acid_1397	1.187e-05	56.0	2DF3Q@1|root,2ZQCR@2|Bacteria,3Y8YJ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_966418_11	264732.Moth_2284	1.92e-110	377.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,42F08@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
MMS3_k127_966418_4	1382304.JNIL01000001_gene3494	4.502e-155	499.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,27838@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04675	Arginosuc_synth
MMS3_k127_966418_29	1386969.AWTB01000023_gene1170	1.511e-24	109.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4GAM7@85026|Gordoniaceae	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
MMS3_k127_966418_20	639030.JHVA01000001_gene66	2.384e-75	266.0	COG0002@1|root,COG0002@2|Bacteria,3Y450@57723|Acidobacteria,2JHSX@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMS3_k127_966418_26	661478.OP10G_2952	1.664e-32	145.0	COG0548@1|root,COG0548@2|Bacteria	2|Bacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8,6.3.2.13	ko:K00930,ko:K01928	ko00220,ko00300,ko00550,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map00550,map01100,map01110,map01130,map01210,map01230	M00028	R02649,R02788	RC00002,RC00043,RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	AA_kinase
MMS3_k127_966418_14	1089553.Tph_c25450	1.584e-99	340.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,42F28@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_966418_31	717606.PaecuDRAFT_0241	3.949e-22	109.0	COG1246@1|root,COG1246@2|Bacteria,1V6TZ@1239|Firmicutes,4HID0@91061|Bacilli,26WS7@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate	argH1	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
MMS3_k127_966418_15	401526.TcarDRAFT_1038	3.847e-95	331.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H2TK@909932|Negativicutes	909932|Negativicutes	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
MMS3_k127_966418_18	1267535.KB906767_gene4528	6.515e-84	289.0	COG0078@1|root,COG0078@2|Bacteria,3Y4R3@57723|Acidobacteria,2JP1M@204432|Acidobacteriia	204432|Acidobacteriia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMS3_k127_966418_2	290317.Cpha266_2588	2.428e-195	626.0	COG0318@1|root,COG0318@2|Bacteria,1FDAB@1090|Chlorobi	1090|Chlorobi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS3_k127_966418_24	886293.Sinac_0413	3.463e-50	192.0	COG0589@1|root,COG0589@2|Bacteria,2J12B@203682|Planctomycetes	203682|Planctomycetes	T	COG0589 Universal stress protein UspA and related	-	-	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
MMS3_k127_966418_13	383372.Rcas_4299	1.88e-101	342.0	COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
MMS3_k127_966418_1	1174528.JH992898_gene1098	2.001e-266	850.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1JKQM@1189|Stigonemataceae	1117|Cyanobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
MMS3_k127_966418_25	113395.AXAI01000007_gene1257	5.393e-38	151.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2TRRN@28211|Alphaproteobacteria,3JVY5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
MMS3_k127_966418_7	398767.Glov_0070	2.095e-145	470.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions	1224|Proteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
MMS3_k127_966418_8	234267.Acid_4084	9.122e-125	410.0	COG2421@1|root,COG2421@2|Bacteria,3Y40F@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Acetamidase Formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
MMS3_k127_966418_16	997346.HMPREF9374_2989	3.761e-89	300.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,4H9PF@91061|Bacilli,27AW2@186824|Thermoactinomycetaceae	91061|Bacilli	S	LamB/YcsF family	ycsF	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
MMS3_k127_966418_21	330214.NIDE4043	6.154e-61	229.0	COG1898@1|root,COG1898@2|Bacteria,3J0K0@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
MMS3_k127_966418_9	1121472.AQWN01000005_gene2445	9.941e-124	404.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,260WK@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_966418_35	63737.Npun_F4488	2.747e-16	91.0	2A5JH@1|root,30U9U@2|Bacteria,1GK5Q@1117|Cyanobacteria,1HTB6@1161|Nostocales	1117|Cyanobacteria	S	DNA-sulfur modification-associated	-	-	-	-	-	-	-	-	-	-	-	-	DndB
MMS3_k127_966418_0	392499.Swit_0915	0.0	1105.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,2U2SA@28211|Alphaproteobacteria,2K2QH@204457|Sphingomonadales	204457|Sphingomonadales	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
MMS3_k127_966418_33	715451.ambt_09225	7.379e-18	89.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,4672B@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	redox protein, regulator of disulfide bond formation	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
MMS3_k127_966418_28	1340493.JNIF01000003_gene2605	2.238e-28	128.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	FHA,VWA,VWA_2
MMS3_k127_966418_3	383372.Rcas_1497	9.057e-161	524.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,374X4@32061|Chloroflexia	32061|Chloroflexia	E	PFAM gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_966418_12	1200792.AKYF01000026_gene165	6.602e-103	345.0	COG3938@1|root,COG3938@2|Bacteria,1TQ61@1239|Firmicutes,4HCR7@91061|Bacilli,271IP@186822|Paenibacillaceae	91061|Bacilli	E	Proline racemase	-	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0071704,GO:1901564	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
MMS3_k127_966418_19	234267.Acid_2302	1.26e-79	279.0	COG2423@1|root,COG2423@2|Bacteria,3Y7M6@57723|Acidobacteria	57723|Acidobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
MMS3_k127_966418_5	1267534.KB906754_gene2671	1.932e-154	497.0	COG2021@1|root,COG2021@2|Bacteria,3Y2FF@57723|Acidobacteria,2JHN8@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM alpha beta hydrolase	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMS3_k127_966418_40	1297742.A176_02837	0.0006332	52.0	COG0457@1|root,COG0457@2|Bacteria	1297742.A176_02837|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_966418_32	1382359.JIAL01000001_gene2418	6.03e-22	108.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
MMS3_k127_966418_34	1347369.CCAD010000094_gene2222	9.485e-17	96.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K03933	-	-	-	-	ko00000	-	AA10,CBM73	-	HYR,He_PIG,Laminin_G_3,Malectin,NPCBM,PKD
MMS3_k127_966418_39	523791.Kkor_1008	0.000148	56.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1S07F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
MMS3_k127_966418_23	1396141.BATP01000007_gene5698	8.296e-51	208.0	COG3210@1|root,COG5184@1|root,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	Beta_helix,Big_5,Peptidase_S74,RCC1,RCC1_2
## 3129 queries scanned
## Total time (seconds): 332.627986907959
## Rate: 9.41 q/s