## Sat Nov 16 05:34:13 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin17/MMS_3_bin.95.fa -m mmseqs --itype genome -o MMS_3_bin.95 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/MMS_3_bin.95 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
MMS3_k127_100459_0	450851.PHZ_c1914	1.082e-240	755.0	COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,2TV2E@28211|Alphaproteobacteria,2KIF0@204458|Caulobacterales	204458|Caulobacterales	C	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8
MMS3_k127_1007917_0	479434.Sthe_0729	2.769e-191	611.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27XEZ@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_1007917_1	479434.Sthe_0728	3.97e-190	602.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi,27XZ6@189775|Thermomicrobia	189775|Thermomicrobia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
MMS3_k127_1014187_0	335543.Sfum_0118	2.198e-52	198.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MQAH@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
MMS3_k127_1018241_15	309801.trd_1499	2.045e-19	97.0	2A4RM@1|root,30TD1@2|Bacteria,2GA1N@200795|Chloroflexi,27YNN@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1018241_3	479434.Sthe_1932	3.892e-106	351.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi,27Y2H@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
MMS3_k127_1018241_1	479434.Sthe_1931	4.121e-209	666.0	COG2812@1|root,COG3266@1|root,COG2812@2|Bacteria,COG3266@2|Bacteria,2G5PK@200795|Chloroflexi,27XHA@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
MMS3_k127_1018241_12	479434.Sthe_1928	1.066e-37	143.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi,27YK5@189775|Thermomicrobia	189775|Thermomicrobia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
MMS3_k127_1018241_0	479434.Sthe_1927	1.822e-236	739.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi,27Y0A@189775|Thermomicrobia	189775|Thermomicrobia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_1018241_14	479434.Sthe_1926	1.262e-27	116.0	COG2919@1|root,COG2919@2|Bacteria,2GBBJ@200795|Chloroflexi,27YP0@189775|Thermomicrobia	189775|Thermomicrobia	D	Septum formation initiator	-	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
MMS3_k127_1018241_4	479434.Sthe_0608	2.433e-96	324.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi,27XVP@189775|Thermomicrobia	189775|Thermomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1018241_8	479434.Sthe_0609	1.063e-61	220.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,27YI4@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1018241_13	479434.Sthe_0610	5.981e-31	132.0	COG5662@1|root,COG5662@2|Bacteria,2G9EH@200795|Chloroflexi,27YQY@189775|Thermomicrobia	189775|Thermomicrobia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1018241_11	309801.trd_1750	4.302e-40	160.0	COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi,27YKA@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
MMS3_k127_1018241_2	926560.KE387027_gene366	4.751e-121	403.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_1018241_7	479434.Sthe_3307	3.397e-79	271.0	COG0500@1|root,COG2226@2|Bacteria,2G8RQ@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_1018241_9	644283.Micau_0272	5.178e-52	190.0	COG0640@1|root,COG0640@2|Bacteria,2IIA5@201174|Actinobacteria,4DDMN@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_1018241_10	1005048.CFU_2238	3.41e-45	166.0	COG0393@1|root,COG0393@2|Bacteria,1QDHT@1224|Proteobacteria,2WCS1@28216|Betaproteobacteria,4784I@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
MMS3_k127_1018241_6	311424.DhcVS_1501	4.939e-87	297.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,34CZ8@301297|Dehalococcoidia	301297|Dehalococcoidia	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_1018241_16	702450.CUW_0437	1.096e-15	87.0	COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,3VR2K@526524|Erysipelotrichia	526524|Erysipelotrichia	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_1018241_5	479434.Sthe_2407	9.506e-88	293.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi,27XNU@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
MMS3_k127_1019119_1	309801.trd_1809	2.858e-35	147.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_1019119_0	479434.Sthe_2071	4e-112	372.0	COG2141@1|root,COG2141@2|Bacteria,2GA05@200795|Chloroflexi,27Y5V@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_1038002_4	479434.Sthe_2226	5.441e-131	431.0	COG2508@1|root,COG2508@2|Bacteria,2G6MB@200795|Chloroflexi,27XVG@189775|Thermomicrobia	189775|Thermomicrobia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
MMS3_k127_1038002_7	1382356.JQMP01000003_gene1377	6.556e-57	203.0	COG2110@1|root,COG2110@2|Bacteria,2G7ID@200795|Chloroflexi,27YKP@189775|Thermomicrobia	189775|Thermomicrobia	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
MMS3_k127_1038002_1	479434.Sthe_2327	1.027e-178	571.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,27XMR@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMS3_k127_1038002_3	479434.Sthe_2326	5.883e-137	443.0	COG0276@1|root,COG0276@2|Bacteria,2G6A2@200795|Chloroflexi,27XJN@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
MMS3_k127_1038002_2	479434.Sthe_2324	3.949e-157	502.0	COG0407@1|root,COG0407@2|Bacteria,2G5NU@200795|Chloroflexi,27XWH@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
MMS3_k127_1038002_8	479434.Sthe_2323	1.785e-46	174.0	COG1917@1|root,COG1917@2|Bacteria,2G9GF@200795|Chloroflexi,27ZAK@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_1038002_0	479434.Sthe_2322	3.018e-192	604.0	COG0640@1|root,COG0640@2|Bacteria,2G8XK@200795|Chloroflexi,27XMQ@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
MMS3_k127_1038002_6	479434.Sthe_2451	6.902e-87	291.0	COG5553@1|root,COG5553@2|Bacteria,2GBCV@200795|Chloroflexi,27YTF@189775|Thermomicrobia	189775|Thermomicrobia	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1038002_5	479434.Sthe_2449	5.072e-99	325.0	COG0161@1|root,COG0161@2|Bacteria,2G62N@200795|Chloroflexi,27XJ0@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
MMS3_k127_1040339_1	1120950.KB892804_gene1476	1.547e-22	105.0	2EBG5@1|root,335GQ@2|Bacteria,2GRUT@201174|Actinobacteria,4DSMC@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1040339_0	1120950.KB892804_gene1476	1.546e-29	126.0	2EBG5@1|root,335GQ@2|Bacteria,2GRUT@201174|Actinobacteria,4DSMC@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1040339_2	1056495.Calag_0843	1.599e-20	100.0	COG3371@1|root,arCOG02008@2157|Archaea,2XRYZ@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
MMS3_k127_1047577_26	316067.Geob_3673	2.045e-10	68.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,43SWS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	RHS protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat
MMS3_k127_1047577_18	479434.Sthe_3221	6.05e-35	137.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_1047577_1	479434.Sthe_2646	3.152e-255	795.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,27XX7@189775|Thermomicrobia	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
MMS3_k127_1047577_14	479434.Sthe_2645	5.244e-66	236.0	COG1052@1|root,COG1052@2|Bacteria,2G5K0@200795|Chloroflexi,27XH1@189775|Thermomicrobia	2|Bacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_1047577_16	479434.Sthe_2644	3.291e-45	167.0	COG3631@1|root,COG3631@2|Bacteria,2GB9X@200795|Chloroflexi,27YEJ@189775|Thermomicrobia	189775|Thermomicrobia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMS3_k127_1047577_4	479434.Sthe_2643	1.508e-166	536.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,27XYX@189775|Thermomicrobia	189775|Thermomicrobia	E	Beta-eliminating lyase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
MMS3_k127_1047577_21	479434.Sthe_2641	8.164e-31	131.0	28SAM@1|root,2ZEMQ@2|Bacteria,2GBPC@200795|Chloroflexi,27YPH@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1047577_11	479434.Sthe_2336	2.105e-79	270.0	COG2258@1|root,COG2258@2|Bacteria,2G7HE@200795|Chloroflexi,27YRB@189775|Thermomicrobia	189775|Thermomicrobia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
MMS3_k127_1047577_23	1463854.JOHT01000014_gene4987	8.569e-23	104.0	COG0778@1|root,COG0778@2|Bacteria,2IPN9@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_1047577_10	479434.Sthe_2637	2.138e-81	282.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi,27Z2V@189775|Thermomicrobia	189775|Thermomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS3_k127_1047577_6	1382356.JQMP01000004_gene118	8.071e-116	378.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi,27XSR@189775|Thermomicrobia	189775|Thermomicrobia	J	Methionine aminopeptidase	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMS3_k127_1047577_19	479434.Sthe_2633	2.998e-33	134.0	2A4RE@1|root,30TCT@2|Bacteria,2GBB8@200795|Chloroflexi,27YMR@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1047577_2	479434.Sthe_2632	1.03e-201	637.0	COG1078@1|root,COG1078@2|Bacteria,2G8B8@200795|Chloroflexi,27XHR@189775|Thermomicrobia	189775|Thermomicrobia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMS3_k127_1047577_7	479434.Sthe_2631	3.493e-106	353.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi,27XF7@189775|Thermomicrobia	189775|Thermomicrobia	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
MMS3_k127_1047577_20	1382356.JQMP01000001_gene1012	2.29e-32	127.0	2A4RT@1|root,30TD7@2|Bacteria,2GBBP@200795|Chloroflexi,27YPD@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1047577_13	479434.Sthe_2629	4.007e-67	236.0	COG0861@1|root,COG0861@2|Bacteria,2G7D5@200795|Chloroflexi,27Z5P@189775|Thermomicrobia	189775|Thermomicrobia	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
MMS3_k127_1047577_5	479434.Sthe_2628	9.117e-162	521.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi,27XWM@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_1047577_3	479434.Sthe_2628	6.034e-193	611.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi,27XWM@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_1047577_15	479434.Sthe_2445	2.195e-62	227.0	COG0697@1|root,COG0697@2|Bacteria,2G8R9@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS3_k127_1047577_22	42256.RradSPS_2354	4.968e-26	114.0	COG4405@1|root,COG4405@2|Bacteria,2IKQP@201174|Actinobacteria	201174|Actinobacteria	I	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
MMS3_k127_1047577_12	1111728.ATYS01000001_gene2413	3.379e-69	244.0	COG2227@1|root,COG2227@2|Bacteria,1QYHT@1224|Proteobacteria,1T3QK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_1047577_25	644966.Tmar_1813	9.377e-19	89.0	COG1359@1|root,COG1359@2|Bacteria,1VM9S@1239|Firmicutes	1239|Firmicutes	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
MMS3_k127_1047577_27	309801.trd_A0662	2.28e-05	50.0	2ATTU@1|root,31JCW@2|Bacteria,2GA4X@200795|Chloroflexi,27Z92@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1047577_8	479434.Sthe_2625	1.346e-99	333.0	COG1216@1|root,COG1216@2|Bacteria,2G69V@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
MMS3_k127_1047577_17	479434.Sthe_2621	2.913e-37	149.0	2A3YM@1|root,30SH1@2|Bacteria,2GAA3@200795|Chloroflexi,27YH4@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1047577_9	479434.Sthe_2611	1.854e-81	276.0	COG0778@1|root,COG0778@2|Bacteria,2G693@200795|Chloroflexi,27XFY@189775|Thermomicrobia	189775|Thermomicrobia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_1047577_24	309801.trd_0594	2.179e-22	102.0	COG3474@1|root,COG3474@2|Bacteria	2|Bacteria	C	electron transfer activity	cbcR	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
MMS3_k127_1047577_0	479434.Sthe_2606	5.952e-288	892.0	COG0405@1|root,COG0405@2|Bacteria,2GABC@200795|Chloroflexi,27XH8@189775|Thermomicrobia	2|Bacteria	E	TIGRFAM gamma-glutamyltransferase	MA20_24045	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_1067071_1	479434.Sthe_0815	3.175e-129	425.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi,27Y6B@189775|Thermomicrobia	189775|Thermomicrobia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
MMS3_k127_1067071_0	479434.Sthe_0814	7.826e-146	467.0	COG0462@1|root,COG0462@2|Bacteria,2G6AF@200795|Chloroflexi,27Y35@189775|Thermomicrobia	189775|Thermomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
MMS3_k127_1073706_1	479434.Sthe_1593	7.694e-69	239.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,27XK6@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
MMS3_k127_1073706_2	479434.Sthe_1592	1.568e-27	115.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi,27YP8@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_1073706_0	479434.Sthe_1591	1.893e-293	913.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,27Y2S@189775|Thermomicrobia	189775|Thermomicrobia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
MMS3_k127_1078649_3	1382356.JQMP01000004_gene615	4.443e-78	271.0	COG3535@1|root,COG3535@2|Bacteria,2GA3G@200795|Chloroflexi,27Z08@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
MMS3_k127_1078649_1	1382356.JQMP01000004_gene615	1.163e-104	350.0	COG3535@1|root,COG3535@2|Bacteria,2GA3G@200795|Chloroflexi,27Z08@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
MMS3_k127_1078649_4	1089553.Tph_c17120	2.7e-72	258.0	COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,24A65@186801|Clostridia,42FRV@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
MMS3_k127_1078649_2	1449126.JQKL01000023_gene211	5.234e-96	325.0	COG2309@1|root,COG2309@2|Bacteria,1UQH1@1239|Firmicutes,249E7@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1078649_0	572546.Arcpr_1409	2.858e-123	401.0	COG0145@1|root,arCOG01511@2157|Archaea,2XT1J@28890|Euryarchaeota	28890|Euryarchaeota	E	COG0145 N-methylhydantoinase A acetone carboxylase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_1083111_4	1499967.BAYZ01000178_gene4646	4.299e-23	102.0	COG1308@1|root,COG1308@2|Bacteria	2|Bacteria	K	protein transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
MMS3_k127_1083111_6	519442.Huta_1637	1.908e-14	79.0	arCOG14964@1|root,arCOG14964@2157|Archaea,2Y0J8@28890|Euryarchaeota,23XF5@183963|Halobacteria	183963|Halobacteria	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
MMS3_k127_1083111_0	1265310.CCBD010000070_gene223	3.084e-161	528.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,233EM@1762|Mycobacteriaceae	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_1083111_2	543632.JOJL01000005_gene4787	8.456e-113	376.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4D94Z@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_1083111_7	399795.CtesDRAFT_PD2525	3.749e-05	51.0	COG1765@1|root,COG1765@2|Bacteria,1N5AV@1224|Proteobacteria,2W41U@28216|Betaproteobacteria	28216|Betaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS3_k127_1083111_1	324602.Caur_3056	2.407e-135	444.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1083111_3	1382356.JQMP01000003_gene2108	6.497e-37	148.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
MMS3_k127_1087410_3	1121440.AUMA01000006_gene1562	6.775e-40	166.0	COG0517@1|root,COG1993@1|root,COG3448@1|root,COG0517@2|Bacteria,COG1993@2|Bacteria,COG3448@2|Bacteria,1N0EM@1224|Proteobacteria,42S43@68525|delta/epsilon subdivisions,2WNI6@28221|Deltaproteobacteria,2MG8I@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Uncharacterized ACR, COG1993	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF190
MMS3_k127_1087410_5	1121861.KB899925_gene2536	2.877e-16	92.0	COG0589@1|root,COG0589@2|Bacteria,1N9BR@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_1087410_0	330214.NIDE4265	8.748e-113	390.0	COG0651@1|root,COG0651@2|Bacteria,3J0HR@40117|Nitrospirae	40117|Nitrospirae	CP	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
MMS3_k127_1087410_2	196367.JNFG01000021_gene4964	9.997e-54	194.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2W1TW@28216|Betaproteobacteria,1KH8J@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7,Oxidored_q6
MMS3_k127_1087410_6	349163.Acry_0607	1.376e-15	81.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2U279@28211|Alphaproteobacteria,2JSJJ@204441|Rhodospirillales	204441|Rhodospirillales	C	oxidoreductase 20 kDa subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
MMS3_k127_1087410_1	1120973.AQXL01000135_gene1426	9.458e-105	364.0	COG3261@1|root,COG3261@2|Bacteria,1VZGX@1239|Firmicutes,4HTTH@91061|Bacilli	91061|Bacilli	C	Nickel-dependent hydrogenase	-	-	-	ko:K15830	-	-	-	-	ko00000	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
MMS3_k127_1087410_4	1218076.BAYB01000019_gene3572	2.044e-21	98.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria,1K2R7@119060|Burkholderiaceae	28216|Betaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
MMS3_k127_1093998_3	479434.Sthe_0849	2.485e-102	346.0	COG0438@1|root,COG0438@2|Bacteria,2G8W3@200795|Chloroflexi,27Y3X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
MMS3_k127_1093998_4	479434.Sthe_0850	8.767e-76	265.0	COG0392@1|root,COG0392@2|Bacteria,2GBB4@200795|Chloroflexi,27YMD@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
MMS3_k127_1093998_1	479434.Sthe_0851	1.9e-139	461.0	COG5650@1|root,COG5650@2|Bacteria,2GB8F@200795|Chloroflexi,27Y1V@189775|Thermomicrobia	189775|Thermomicrobia	S	phosphatidylinositol metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1093998_2	479434.Sthe_0852	4.963e-120	400.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wxcA	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_1,Methyltransf_21
MMS3_k127_1093998_5	118168.MC7420_1063	4.888e-09	68.0	COG2227@1|root,COG2227@2|Bacteria,1G3HH@1117|Cyanobacteria,1HAU1@1150|Oscillatoriales	1117|Cyanobacteria	H	Mycolic acid cyclopropane synthetase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
MMS3_k127_1093998_0	479434.Sthe_0854	3.899e-239	749.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Z0M@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_1098493_10	479434.Sthe_1757	1.041e-65	236.0	COG1388@1|root,COG4990@1|root,COG1388@2|Bacteria,COG4990@2|Bacteria,2G95J@200795|Chloroflexi,27Y1K@189775|Thermomicrobia	189775|Thermomicrobia	M	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_C39_2
MMS3_k127_1098493_8	479434.Sthe_1758	1.731e-73	255.0	COG0120@1|root,COG0120@2|Bacteria,2G6NN@200795|Chloroflexi,27Y9V@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
MMS3_k127_1098493_3	1382356.JQMP01000004_gene545	3.415e-144	463.0	COG3958@1|root,COG3958@2|Bacteria,2G8E1@200795|Chloroflexi,27XY5@189775|Thermomicrobia	189775|Thermomicrobia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMS3_k127_1098493_4	479434.Sthe_1760	8.481e-134	432.0	COG3959@1|root,COG3959@2|Bacteria,2GA6J@200795|Chloroflexi,27XHY@189775|Thermomicrobia	189775|Thermomicrobia	G	XFP N-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
MMS3_k127_1098493_2	479434.Sthe_1766	4.002e-154	497.0	COG3103@1|root,COG4991@2|Bacteria,2G8N3@200795|Chloroflexi,27XRF@189775|Thermomicrobia	189775|Thermomicrobia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
MMS3_k127_1098493_9	479434.Sthe_1767	1.693e-72	254.0	COG1277@1|root,COG1277@2|Bacteria,2GBGK@200795|Chloroflexi,27YD7@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_1098493_5	479434.Sthe_1768	3.225e-112	370.0	COG1131@1|root,COG1131@2|Bacteria,2G5QI@200795|Chloroflexi,27XXC@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1098493_6	479434.Sthe_1769	5.822e-91	312.0	COG0392@1|root,COG0392@2|Bacteria,2GB9H@200795|Chloroflexi,27YB9@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
MMS3_k127_1098493_7	331869.BAL199_03719	9.096e-74	263.0	COG4927@1|root,COG4927@2|Bacteria,1NKHP@1224|Proteobacteria,2U18B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
MMS3_k127_1098493_0	1382356.JQMP01000001_gene704	1.591e-192	626.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_1098493_1	479434.Sthe_2595	8.8e-177	561.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	2|Bacteria	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_1108593_2	1385511.N783_00485	2.889e-53	205.0	COG3395@1|root,COG3395@2|Bacteria,1TPNP@1239|Firmicutes,4HAGQ@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
MMS3_k127_1108593_0	401526.TcarDRAFT_2440	1.548e-144	470.0	COG3875@1|root,COG3875@2|Bacteria,1TUCQ@1239|Firmicutes,4H66I@909932|Negativicutes	909932|Negativicutes	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
MMS3_k127_1108593_1	1120746.CCNL01000008_gene799	2.923e-102	343.0	COG1995@1|root,COG1995@2|Bacteria,2NNWZ@2323|unclassified Bacteria	2|Bacteria	H	Pyridoxal phosphate biosynthetic protein PdxA	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1357_C,DUF1537,PdxA
MMS3_k127_1108593_3	479434.Sthe_0096	4.716e-08	54.0	COG2234@1|root,COG2234@2|Bacteria,2G9MK@200795|Chloroflexi,27XKJ@189775|Thermomicrobia	189775|Thermomicrobia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_11092_5	479434.Sthe_2047	1.052e-26	109.0	COG0714@1|root,COG0714@2|Bacteria,2G9S0@200795|Chloroflexi	200795|Chloroflexi	S	AAA domain (dynein-related subfamily)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5
MMS3_k127_11092_1	479434.Sthe_2048	3.455e-236	745.0	COG4548@1|root,COG4548@2|Bacteria	2|Bacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
MMS3_k127_11092_3	485913.Krac_6983	2.478e-127	424.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	AhpC-TSA,MauE
MMS3_k127_11092_7	479434.Sthe_2049	1.64e-17	90.0	2BQPG@1|root,32JJW@2|Bacteria,2GA5I@200795|Chloroflexi,27ZBC@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_11092_6	477974.Daud_0597	1.494e-17	89.0	COG3339@1|root,COG3339@2|Bacteria,1UDER@1239|Firmicutes,25I4F@186801|Clostridia,2667H@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
MMS3_k127_11092_8	1449351.RISW2_03620	4.214e-09	63.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MVYW@1224|Proteobacteria,2TS8D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome C oxidase subunit	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
MMS3_k127_11092_0	479434.Sthe_2054	9.083e-242	757.0	COG0028@1|root,COG0028@2|Bacteria,2G810@200795|Chloroflexi,27XX3@189775|Thermomicrobia	189775|Thermomicrobia	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_11092_4	42256.RradSPS_1003	8.318e-104	352.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4CQNB@84995|Rubrobacteria	84995|Rubrobacteria	P	pump membrane protein	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
MMS3_k127_11092_2	479434.Sthe_2056	1.834e-128	415.0	COG0596@1|root,COG0596@2|Bacteria,2GA00@200795|Chloroflexi,27Y3R@189775|Thermomicrobia	189775|Thermomicrobia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMS3_k127_1112929_1	479434.Sthe_1679	5.95e-80	275.0	COG0842@1|root,COG0842@2|Bacteria,2G915@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_1112929_0	1380346.JNIH01000001_gene4054	2.123e-123	407.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_1113042_2	485913.Krac_10658	3.46e-29	126.0	COG1802@1|root,COG1802@2|Bacteria	2|Bacteria	K	Transcriptional regulator	benC	-	-	ko:K05784,ko:K21727	ko00362,ko00364,ko00622,ko00627,ko01100,ko01120,ko01220,map00362,map00364,map00622,map00627,map01100,map01120,map01220	M00551	R03023,R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110	RC00046,RC00270,RC01378,RC01450,RC01910	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,FCD,Fer2,GntR,NAD_binding_1,adh_short,adh_short_C2
MMS3_k127_1113042_0	768066.HELO_3169	1.92e-30	134.0	COG0673@1|root,COG0673@2|Bacteria,1NVIW@1224|Proteobacteria,1SEMU@1236|Gammaproteobacteria,1XP1U@135619|Oceanospirillales	135619|Oceanospirillales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_1113042_3	485913.Krac_0922	6.605e-08	54.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_1113042_1	266117.Rxyl_1041	1.965e-29	121.0	COG1670@1|root,COG1670@2|Bacteria,2HP6V@201174|Actinobacteria,4CTRA@84995|Rubrobacteria	84995|Rubrobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_1113507_0	479434.Sthe_1163	2.663e-178	567.0	COG0768@1|root,COG0768@2|Bacteria,2G7V1@200795|Chloroflexi,27XRU@189775|Thermomicrobia	189775|Thermomicrobia	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
MMS3_k127_1113507_3	479434.Sthe_1164	2.249e-37	146.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi,27YGT@189775|Thermomicrobia	189775|Thermomicrobia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
MMS3_k127_1113507_4	309801.trd_0833	1.554e-05	50.0	2E7PW@1|root,3325F@2|Bacteria,2G7GZ@200795|Chloroflexi,27YJP@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1113507_2	479434.Sthe_1165	4.469e-38	151.0	2E7PW@1|root,3325F@2|Bacteria,2G7GZ@200795|Chloroflexi,27YJP@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1113507_1	479434.Sthe_1166	1.832e-173	559.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi,27XPX@189775|Thermomicrobia	189775|Thermomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMS3_k127_1138299_0	479434.Sthe_2652	3.262e-161	511.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi,27Y13@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMS3_k127_1138299_1	479434.Sthe_2651	3.558e-154	492.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,27XR5@189775|Thermomicrobia	189775|Thermomicrobia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
MMS3_k127_1138299_2	479434.Sthe_2650	6.645e-98	326.0	COG1738@1|root,COG1738@2|Bacteria,2G6BZ@200795|Chloroflexi,27XFP@189775|Thermomicrobia	189775|Thermomicrobia	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
MMS3_k127_1152808_4	479434.Sthe_1989	3.655e-50	184.0	COG1589@1|root,COG1589@2|Bacteria,2G7FV@200795|Chloroflexi,27YKW@189775|Thermomicrobia	189775|Thermomicrobia	D	POTRA domain, FtsQ-type	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
MMS3_k127_1152808_1	1382356.JQMP01000004_gene466	2.488e-146	473.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
MMS3_k127_1152808_2	1382356.JQMP01000004_gene467	1.59e-114	378.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi,27YJX@189775|Thermomicrobia	189775|Thermomicrobia	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
MMS3_k127_1152808_0	479434.Sthe_1991	4.858e-167	537.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi,27XZD@189775|Thermomicrobia	189775|Thermomicrobia	M	Mur ligase family, catalytic domain	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_1152808_3	479434.Sthe_1992	3.978e-91	307.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi,27XXN@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
MMS3_k127_1169360_3	797209.ZOD2009_21512	1.019e-42	165.0	COG3608@1|root,arCOG02890@2157|Archaea,2XUVB@28890|Euryarchaeota,23UWM@183963|Halobacteria	183963|Halobacteria	S	Deacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
MMS3_k127_1169360_1	926550.CLDAP_35020	1.901e-119	403.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
MMS3_k127_1169360_0	479434.Sthe_1301	0.0	1793.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi,27XEX@189775|Thermomicrobia	189775|Thermomicrobia	L	Bacterial DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
MMS3_k127_1169360_2	479434.Sthe_1302	3.736e-57	202.0	COG1396@1|root,COG1396@2|Bacteria,2GBAN@200795|Chloroflexi,27YIS@189775|Thermomicrobia	189775|Thermomicrobia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
MMS3_k127_1189682_9	1382356.JQMP01000003_gene2462	2.881e-33	130.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi,27Y2Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_1189682_4	479434.Sthe_1496	7.622e-115	376.0	COG0351@1|root,COG0351@2|Bacteria,2G5R7@200795|Chloroflexi,27XQP@189775|Thermomicrobia	189775|Thermomicrobia	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
MMS3_k127_1189682_3	479434.Sthe_1495	1.453e-134	432.0	COG2022@1|root,COG2022@2|Bacteria,2G6DX@200795|Chloroflexi,27XT9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
MMS3_k127_1189682_6	1382356.JQMP01000003_gene2469	1.257e-71	248.0	COG0352@1|root,COG0352@2|Bacteria,2G6P0@200795|Chloroflexi,27Y70@189775|Thermomicrobia	189775|Thermomicrobia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
MMS3_k127_1189682_7	479434.Sthe_1493	4.694e-69	241.0	COG0352@1|root,COG0352@2|Bacteria,2G9BW@200795|Chloroflexi,27YDG@189775|Thermomicrobia	189775|Thermomicrobia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
MMS3_k127_1189682_11	479434.Sthe_1492	3.913e-20	91.0	COG2104@1|root,COG2104@2|Bacteria,2GBFH@200795|Chloroflexi,27ZAZ@189775|Thermomicrobia	189775|Thermomicrobia	H	thiamine biosynthesis protein ThiS	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMS3_k127_1189682_8	479434.Sthe_1491	1.401e-48	176.0	COG3695@1|root,COG3695@2|Bacteria,2G7CY@200795|Chloroflexi,27YDT@189775|Thermomicrobia	189775|Thermomicrobia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
MMS3_k127_1189682_10	1382356.JQMP01000003_gene2473	8.694e-30	122.0	2ADJ7@1|root,3139N@2|Bacteria,2GA53@200795|Chloroflexi,27Z9V@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1189682_1	479434.Sthe_1490	7.702e-222	701.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
MMS3_k127_1189682_0	479434.Sthe_1489	0.0	1298.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi,27XJU@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
MMS3_k127_1189682_5	479434.Sthe_1466	4.53e-83	282.0	COG3382@1|root,COG3382@2|Bacteria,2G96A@200795|Chloroflexi,27Y99@189775|Thermomicrobia	189775|Thermomicrobia	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
MMS3_k127_1189682_2	479434.Sthe_1464	1.619e-192	610.0	COG0297@1|root,COG0297@2|Bacteria,2GA6I@200795|Chloroflexi,27XJX@189775|Thermomicrobia	189775|Thermomicrobia	G	Glycosyl transferase 4-like domain	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_1191657_9	378806.STAUR_4854	2.361e-26	111.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
MMS3_k127_1191657_0	479434.Sthe_2205	8.897e-198	627.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	2|Bacteria	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1191657_1	479434.Sthe_0169	1.84e-176	564.0	COG0486@1|root,COG0486@2|Bacteria,2G647@200795|Chloroflexi	200795|Chloroflexi	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
MMS3_k127_1191657_4	479434.Sthe_0168	6.393e-118	386.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi,27XUV@189775|Thermomicrobia	189775|Thermomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
MMS3_k127_1191657_5	479434.Sthe_0167	1.247e-95	318.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi,27XWI@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative single-stranded nucleic acids-binding domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,R3H
MMS3_k127_1191657_8	479434.Sthe_0165	1.177e-32	128.0	COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi,27YMP@189775|Thermomicrobia	189775|Thermomicrobia	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
MMS3_k127_1191657_7	479434.Sthe_0164	2.619e-44	164.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi,27YJ4@189775|Thermomicrobia	189775|Thermomicrobia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
MMS3_k127_1191657_10	479434.Sthe_0163	5.004e-19	89.0	COG0230@1|root,COG0230@2|Bacteria,2G7BX@200795|Chloroflexi,27YQV@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
MMS3_k127_1191657_3	1121861.KB899919_gene2785	5.219e-145	471.0	COG0006@1|root,COG0006@2|Bacteria,1MX9N@1224|Proteobacteria,2TUN2@28211|Alphaproteobacteria,2JUCM@204441|Rhodospirillales	204441|Rhodospirillales	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_1191657_6	479434.Sthe_2029	3.28e-58	206.0	COG1546@1|root,COG1546@2|Bacteria,2G6U8@200795|Chloroflexi,27YG1@189775|Thermomicrobia	189775|Thermomicrobia	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
MMS3_k127_1191657_2	479434.Sthe_2028	8.749e-154	491.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,27XSH@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1193886_6	479434.Sthe_2339	2.328e-10	65.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,27YHA@189775|Thermomicrobia	189775|Thermomicrobia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
MMS3_k127_1193886_0	479434.Sthe_1275	7.483e-174	552.0	COG3191@1|root,COG3191@2|Bacteria,2G83Q@200795|Chloroflexi	200795|Chloroflexi	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
MMS3_k127_1193886_1	266779.Meso_3631	3.709e-126	429.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,43JIS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
MMS3_k127_1193886_3	1123023.JIAI01000001_gene6765	3.27e-111	367.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
MMS3_k127_1193886_2	1283283.ATXA01000023_gene261	4.214e-120	393.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4ETNA@85013|Frankiales	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
MMS3_k127_1193886_4	1382356.JQMP01000001_gene766	4.716e-109	360.0	COG0119@1|root,COG0119@2|Bacteria,2G7M0@200795|Chloroflexi,27YV0@189775|Thermomicrobia	189775|Thermomicrobia	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
MMS3_k127_1193886_5	479434.Sthe_2511	2.408e-28	115.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
MMS3_k127_1199315_3	479434.Sthe_3024	1.269e-81	278.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,27XZC@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
MMS3_k127_1199315_2	479434.Sthe_3025	8.448e-134	441.0	COG1169@1|root,COG1169@2|Bacteria,2GADW@200795|Chloroflexi,27Y2P@189775|Thermomicrobia	189775|Thermomicrobia	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
MMS3_k127_1199315_4	479434.Sthe_3026	2.307e-78	267.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi,27Y8Z@189775|Thermomicrobia	189775|Thermomicrobia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
MMS3_k127_1199315_7	1068980.ARVW01000001_gene6491	5.697e-37	157.0	COG0477@1|root,COG2814@2|Bacteria,2GK22@201174|Actinobacteria,4DZAE@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1199315_1	479434.Sthe_0189	6.129e-156	503.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_1199315_8	351160.RCIX165	7.279e-18	90.0	COG4978@1|root,arCOG03200@2157|Archaea	2157|Archaea	KT	transcription activator, effector binding	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
MMS3_k127_1199315_5	479434.Sthe_3027	5.694e-55	200.0	COG0494@1|root,COG0494@2|Bacteria,2G6ZK@200795|Chloroflexi,27YH8@189775|Thermomicrobia	189775|Thermomicrobia	L	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
MMS3_k127_1199315_0	479434.Sthe_3028	2.035e-280	871.0	COG1351@1|root,COG1351@2|Bacteria,2G9ZK@200795|Chloroflexi,27XV1@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
MMS3_k127_1199315_6	479434.Sthe_1130	1.186e-49	183.0	COG2318@1|root,COG2318@2|Bacteria,2G77R@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_1199315_10	998674.ATTE01000001_gene3077	1.028e-15	83.0	296JA@1|root,2ZTUV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1199315_9	1123024.AUII01000024_gene179	8.414e-16	80.0	296JA@1|root,2ZTUV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1200163_0	479434.Sthe_0383	2.42e-308	955.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi,27XYG@189775|Thermomicrobia	189775|Thermomicrobia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
MMS3_k127_1224520_1	479434.Sthe_0439	6.252e-103	349.0	COG1686@1|root,COG1686@2|Bacteria,2G8TU@200795|Chloroflexi,27XVX@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
MMS3_k127_1224520_0	309801.trd_0440	3.784e-174	549.0	COG2006@1|root,COG2006@2|Bacteria,2GA2Y@200795|Chloroflexi,27YWH@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
MMS3_k127_1224613_4	309801.trd_A0602	4.824e-54	192.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi	200795|Chloroflexi	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
MMS3_k127_1224613_3	479434.Sthe_1819	2.251e-54	195.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi,27Z9F@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMS3_k127_1224613_2	479434.Sthe_3129	7.627e-91	304.0	COG4221@1|root,COG4221@2|Bacteria,2G8WF@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMS3_k127_1224613_6	1227487.C474_10791	2.518e-32	127.0	arCOG13015@1|root,arCOG13015@2157|Archaea,2XYY4@28890|Euryarchaeota,23XB6@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
MMS3_k127_1224613_5	479434.Sthe_1368	4.574e-33	133.0	2DPD4@1|root,331JQ@2|Bacteria,2G9MC@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
MMS3_k127_1224613_1	479434.Sthe_1367	1.207e-130	424.0	COG2378@1|root,COG2378@2|Bacteria,2G8BW@200795|Chloroflexi	200795|Chloroflexi	K	Helix-turn-helix type 11 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
MMS3_k127_1224613_0	1382356.JQMP01000004_gene185	5.502e-142	460.0	COG2042@1|root,COG3376@2|Bacteria,2G83J@200795|Chloroflexi	200795|Chloroflexi	S	High-affinity nickel-transport protein	-	-	-	-	-	-	-	-	-	-	-	-	NicO
MMS3_k127_1224613_7	309801.trd_1534	1.014e-09	66.0	COG2010@1|root,COG2010@2|Bacteria,2G9FK@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1225305_1	479434.Sthe_1715	3.293e-43	164.0	COG0859@1|root,COG0859@2|Bacteria,2G8F3@200795|Chloroflexi,27Y39@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
MMS3_k127_1225305_0	479434.Sthe_1716	9.809e-214	667.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,27Y0U@189775|Thermomicrobia	189775|Thermomicrobia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
MMS3_k127_1225305_3	479434.Sthe_1717	1.378e-18	94.0	2A4RN@1|root,30TD2@2|Bacteria,2GBBI@200795|Chloroflexi,27YNV@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1225305_2	1382356.JQMP01000003_gene2170	2.564e-41	156.0	COG1560@1|root,COG1560@2|Bacteria,2G7BA@200795|Chloroflexi,27Y7M@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMS3_k127_1238984_3	1089548.KI783301_gene2862	1.256e-84	291.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3WEN7@539002|Bacillales incertae sedis	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_1238984_5	479434.Sthe_1966	9.903e-66	231.0	COG3634@1|root,COG3634@2|Bacteria,2GBT2@200795|Chloroflexi,27Z89@189775|Thermomicrobia	189775|Thermomicrobia	O	alkyl hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1238984_7	452637.Oter_1468	9.019e-24	107.0	COG0640@1|root,COG0640@2|Bacteria,46WX7@74201|Verrucomicrobia	2|Bacteria	K	PFAM regulatory protein ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
MMS3_k127_1238984_4	1380394.JADL01000010_gene4354	5.283e-84	288.0	COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2TR54@28211|Alphaproteobacteria,2JV21@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_1238984_6	279010.BL00086	3.026e-41	162.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus	91061|Bacilli	K	transcriptional	yvoA	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
MMS3_k127_1238984_2	1033743.CAES01000007_gene2016	2.508e-136	443.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,26VB1@186822|Paenibacillaceae	91061|Bacilli	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_1238984_1	479434.Sthe_0274	2.08e-295	913.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi,27XUU@189775|Thermomicrobia	2|Bacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01474	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
MMS3_k127_1238984_0	479434.Sthe_0273	0.0	1066.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	2|Bacteria	EQ	Hydantoinaseoxoprolinase domain protein	oplaH	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
MMS3_k127_124062_13	309801.trd_A0566	6.137e-83	280.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi,27Z3G@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMS3_k127_124062_0	479434.Sthe_2780	2.542e-276	863.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G7MH@200795|Chloroflexi,27XJR@189775|Thermomicrobia	189775|Thermomicrobia	EU	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_124062_11	309801.trd_A0569	4.226e-95	316.0	COG2197@1|root,COG2197@2|Bacteria,2G8H8@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_124062_4	309801.trd_A0570	1.652e-140	458.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8NJ@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
MMS3_k127_124062_10	1100720.ALKN01000052_gene507	6.948e-102	346.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_124062_8	479434.Sthe_3346	5.275e-119	394.0	COG0265@1|root,COG0265@2|Bacteria,2G8RK@200795|Chloroflexi,27Y6G@189775|Thermomicrobia	189775|Thermomicrobia	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_124062_9	479434.Sthe_2871	5.024e-112	376.0	COG0174@1|root,COG0174@2|Bacteria,2G62E@200795|Chloroflexi,27Z5C@189775|Thermomicrobia	189775|Thermomicrobia	E	Glutamine synthetase N-terminal domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
MMS3_k127_124062_5	1382356.JQMP01000003_gene2130	7.173e-135	442.0	COG2159@1|root,COG2159@2|Bacteria,2G6EZ@200795|Chloroflexi,27YN4@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_124062_2	479434.Sthe_2788	3.311e-165	527.0	COG0006@1|root,COG0006@2|Bacteria,2G6AH@200795|Chloroflexi,27XJK@189775|Thermomicrobia	189775|Thermomicrobia	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_124062_7	1519464.HY22_08035	7.111e-123	404.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11,4.1.1.45	ko:K00453,ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R00678,R04323	RC00356,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
MMS3_k127_124062_14	479434.Sthe_2722	2.362e-68	239.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_124062_1	479434.Sthe_2791	1.989e-209	670.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G7MH@200795|Chloroflexi,27XJR@189775|Thermomicrobia	200795|Chloroflexi	EU	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_124062_15	479434.Sthe_2792	6.46e-51	185.0	COG0785@1|root,COG0785@2|Bacteria,2GA16@200795|Chloroflexi,27YIP@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_124062_3	479434.Sthe_2802	6.051e-153	488.0	COG0329@1|root,COG0329@2|Bacteria,2G6U3@200795|Chloroflexi,27Y9D@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_124062_6	479434.Sthe_2803	4.054e-126	409.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi,27YYJ@189775|Thermomicrobia	189775|Thermomicrobia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.1.1.68	ko:K05921	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04134,R04380	RC01085,RC02669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
MMS3_k127_124062_12	1382356.JQMP01000001_gene950	1.344e-94	312.0	COG2368@1|root,COG2368@2|Bacteria,2GAH7@200795|Chloroflexi,27XER@189775|Thermomicrobia	189775|Thermomicrobia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
MMS3_k127_124334_1	408672.NBCG_01641	3.038e-68	241.0	COG0500@1|root,COG2226@2|Bacteria,2IA9Q@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_124334_0	479434.Sthe_0896	1.666e-118	394.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_1257464_5	391587.KAOT1_03912	0.0005155	46.0	2DN9V@1|root,32WBN@2|Bacteria,4NU3Q@976|Bacteroidetes,1I6UQ@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4935)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4935
MMS3_k127_1257464_2	1382356.JQMP01000001_gene772	7.778e-66	230.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi,27Z6H@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
MMS3_k127_1257464_1	1382356.JQMP01000001_gene771	6.82e-117	385.0	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi,27YUM@189775|Thermomicrobia	189775|Thermomicrobia	H	ApbE family	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMS3_k127_1257464_4	1382356.JQMP01000001_gene769	4.411e-21	101.0	COG1141@1|root,COG1141@2|Bacteria,2GBFF@200795|Chloroflexi,27ZAP@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_15
MMS3_k127_1257464_0	1382356.JQMP01000001_gene768	2.901e-163	528.0	COG1894@1|root,COG1894@2|Bacteria,2GBW4@200795|Chloroflexi,27YVY@189775|Thermomicrobia	189775|Thermomicrobia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
MMS3_k127_1257464_3	287986.DV20_21530	8.422e-31	131.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
MMS3_k127_1272703_0	479434.Sthe_2363	0.0	1066.0	COG0209@1|root,COG0209@2|Bacteria,2G8RN@200795|Chloroflexi,27Y2V@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
MMS3_k127_1272703_8	208439.AJAP_19500	4.848e-47	174.0	2D579@1|root,32TID@2|Bacteria,2IMWE@201174|Actinobacteria,4E636@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1272703_4	1382356.JQMP01000004_gene503	9.981e-67	232.0	COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia	189775|Thermomicrobia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_1272703_6	1382356.JQMP01000004_gene503	4.31e-51	187.0	COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia	189775|Thermomicrobia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_1272703_5	479434.Sthe_0250	1.04e-62	235.0	COG0726@1|root,COG0726@2|Bacteria,2G76U@200795|Chloroflexi	200795|Chloroflexi	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
MMS3_k127_1272703_11	1382356.JQMP01000003_gene1850	1.516e-05	49.0	2A4RX@1|root,30TDB@2|Bacteria,2GBBQ@200795|Chloroflexi,27YPF@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1272703_10	1535287.JP74_22455	5.292e-15	79.0	2EME0@1|root,33F2V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1272703_1	479434.Sthe_2364	8.909e-186	593.0	COG0076@1|root,COG0076@2|Bacteria,2G8Q9@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
MMS3_k127_1272703_7	266117.Rxyl_0172	5.649e-51	192.0	COG0500@1|root,COG2226@2|Bacteria,2HEP0@201174|Actinobacteria,4CTFJ@84995|Rubrobacteria	84995|Rubrobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_1272703_3	479434.Sthe_2400	1.116e-110	365.0	COG1122@1|root,COG1122@2|Bacteria,2G6FK@200795|Chloroflexi,27Y82@189775|Thermomicrobia	189775|Thermomicrobia	P	ECF transporter, substrate-specific component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF_trnsprt
MMS3_k127_1272703_2	479434.Sthe_2399	1.003e-123	403.0	COG0614@1|root,COG0614@2|Bacteria,2G6EF@200795|Chloroflexi,27XQF@189775|Thermomicrobia	189775|Thermomicrobia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
MMS3_k127_1272703_9	1128421.JAGA01000003_gene3585	5.324e-31	130.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
MMS3_k127_12915_4	1173024.KI912149_gene6263	6.923e-38	144.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1GKR9@1117|Cyanobacteria,1JMKR@1189|Stigonemataceae	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_12915_5	479434.Sthe_3249	4.212e-14	76.0	COG4392@1|root,COG4392@2|Bacteria	2|Bacteria	E	branched-chain amino acid	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
MMS3_k127_12915_3	479434.Sthe_3248	1.176e-61	222.0	COG1296@1|root,COG1296@2|Bacteria,2G6SG@200795|Chloroflexi	200795|Chloroflexi	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
MMS3_k127_12915_2	479434.Sthe_3247	9.949e-96	323.0	28VEA@1|root,2ZHGV@2|Bacteria	2|Bacteria	K	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_12915_1	479434.Sthe_3015	4.495e-194	617.0	COG0318@1|root,COG0318@2|Bacteria,2G7PF@200795|Chloroflexi,27XJD@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_12915_0	479434.Sthe_3014	0.0	1114.0	COG0281@1|root,COG0281@2|Bacteria,2G65R@200795|Chloroflexi,27XFK@189775|Thermomicrobia	189775|Thermomicrobia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
MMS3_k127_1294213_0	1121861.KB899936_gene378	2.665e-170	544.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2JQP4@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_1294213_1	420324.KI912000_gene8135	3.594e-98	330.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_1313356_1	485913.Krac_3425	7.878e-270	846.0	COG1132@1|root,COG1132@2|Bacteria,2G65H@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_1313356_2	485913.Krac_3426	4.745e-241	757.0	COG1132@1|root,COG1132@2|Bacteria,2G5RC@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_1313356_14	479434.Sthe_0982	8.17e-71	242.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi,27YCP@189775|Thermomicrobia	189775|Thermomicrobia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
MMS3_k127_1313356_11	479434.Sthe_0981	6.854e-91	306.0	COG0500@1|root,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi,27Y5W@189775|Thermomicrobia	189775|Thermomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_1313356_12	479434.Sthe_0980	5.83e-82	276.0	COG1898@1|root,COG1898@2|Bacteria,2GB9B@200795|Chloroflexi,27Y8P@189775|Thermomicrobia	189775|Thermomicrobia	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
MMS3_k127_1313356_4	479434.Sthe_0979	1.333e-172	552.0	COG0128@1|root,COG0128@2|Bacteria,2G6S6@200795|Chloroflexi,27Y0N@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
MMS3_k127_1313356_3	479434.Sthe_0978	3.993e-189	594.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi,27XHB@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
MMS3_k127_1313356_7	479434.Sthe_0977	2.148e-96	323.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi,27Y6X@189775|Thermomicrobia	189775|Thermomicrobia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_1313356_5	479434.Sthe_0976	6.161e-157	516.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,27XQ9@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_1313356_6	479434.Sthe_0971	4.395e-98	336.0	COG5479@1|root,COG5479@2|Bacteria,2GA41@200795|Chloroflexi,27Z54@189775|Thermomicrobia	189775|Thermomicrobia	M	peptidoglycan receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1313356_16	479434.Sthe_0970	5.825e-33	130.0	COG0283@1|root,COG0283@2|Bacteria,2G7E1@200795|Chloroflexi,27YP4@189775|Thermomicrobia	189775|Thermomicrobia	F	belongs to the cytidylate kinase family. Type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1313356_13	479434.Sthe_0969	3.925e-81	276.0	COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi,27Y8F@189775|Thermomicrobia	189775|Thermomicrobia	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
MMS3_k127_1313356_17	575589.HMPREF0018_00882	1.714e-11	74.0	COG1011@1|root,COG1011@2|Bacteria,1MVF8@1224|Proteobacteria,1T28K@1236|Gammaproteobacteria,3NMDW@468|Moraxellaceae	1236|Gammaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS3_k127_1313356_9	479434.Sthe_0965	9.686e-96	320.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi,27XR6@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
MMS3_k127_1313356_8	479434.Sthe_0964	2.751e-96	321.0	COG1136@1|root,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,27Y7U@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1313356_15	448385.sce8089	9.671e-38	151.0	2BZKP@1|root,337K0@2|Bacteria,1N9R0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1313356_0	479434.Sthe_0963	8.54e-312	973.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,27Y16@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1313356_10	479434.Sthe_0962	3.526e-95	322.0	COG0845@1|root,COG0845@2|Bacteria,2G8US@200795|Chloroflexi,27YC2@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
MMS3_k127_1342467_3	479434.Sthe_1762	1.711e-63	221.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1342467_4	479434.Sthe_2021	4.535e-52	186.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMS3_k127_1342467_2	525904.Tter_1857	2.146e-67	240.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_1342467_1	43354.JOIJ01000010_gene2611	8.3e-111	368.0	COG2513@1|root,COG2513@2|Bacteria,2GJZZ@201174|Actinobacteria,4E0PY@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	4.1.3.32	ko:K20454	ko00760,ko01120,map00760,map01120	-	R01355	RC00286,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
MMS3_k127_1342467_0	479434.Sthe_2026	3.424e-149	486.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria	2|Bacteria	T	Histidine kinase	adeS	-	2.7.13.3	ko:K02484,ko:K07642,ko:K07644,ko:K18143	ko01501,ko02020,map01501,map02020	M00450,M00452,M00645,M00646,M00648,M00649,M00655,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
MMS3_k127_1342979_3	479434.Sthe_1563	1.41e-20	96.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia	2|Bacteria	S	Belongs to the peptidase M50B family	VVA0737	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
MMS3_k127_1342979_2	479434.Sthe_1562	2.941e-41	154.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi,27YH0@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
MMS3_k127_1342979_1	479434.Sthe_1560	5.649e-44	165.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi,27YI8@189775|Thermomicrobia	189775|Thermomicrobia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
MMS3_k127_1342979_0	479434.Sthe_1559	1.601e-96	329.0	COG3299@1|root,COG3299@2|Bacteria,2GA9P@200795|Chloroflexi,27YCN@189775|Thermomicrobia	189775|Thermomicrobia	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1354063_6	479434.Sthe_0935	3.402e-46	169.0	COG0505@1|root,COG0505@2|Bacteria,2G5S1@200795|Chloroflexi,27XJV@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
MMS3_k127_1354063_0	479434.Sthe_0936	0.0	1760.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,27XRT@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
MMS3_k127_1354063_7	702450.CUW_1375	9.106e-05	46.0	COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes	1239|Firmicutes	P	calcium proton	cax	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
MMS3_k127_1354063_4	383372.Rcas_3782	2.395e-82	282.0	COG0387@1|root,COG0387@2|Bacteria,2G6GE@200795|Chloroflexi,37714@32061|Chloroflexia	32061|Chloroflexia	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
MMS3_k127_1354063_5	479434.Sthe_0937	2.787e-75	258.0	COG0461@1|root,COG0461@2|Bacteria,2G6RG@200795|Chloroflexi,27YBT@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
MMS3_k127_1354063_3	479434.Sthe_2685	1.024e-152	491.0	COG0624@1|root,COG0624@2|Bacteria,2G7PC@200795|Chloroflexi,27YEV@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_1354063_2	479434.Sthe_2686	6.448e-157	504.0	COG0498@1|root,COG0498@2|Bacteria,2G6D6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_1354063_1	479434.Sthe_0939	2.315e-312	969.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi,27XIY@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMS3_k127_1370954_8	1191523.MROS_2687	3.347e-26	112.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
MMS3_k127_1370954_5	1183438.GKIL_3645	1.293e-51	185.0	COG1970@1|root,COG1970@2|Bacteria,1G829@1117|Cyanobacteria	1117|Cyanobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
MMS3_k127_1370954_6	479434.Sthe_3205	4.047e-41	156.0	COG5428@1|root,COG5428@2|Bacteria,2GBFE@200795|Chloroflexi,27ZAM@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1370954_7	1386089.N865_18765	8.727e-27	114.0	2E7YB@1|root,332CR@2|Bacteria,2IRTP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
MMS3_k127_1370954_4	756499.Desde_3375	7.496e-53	193.0	COG4832@1|root,COG4832@2|Bacteria	2|Bacteria	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
MMS3_k127_1370954_3	479434.Sthe_3318	4.381e-72	258.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	rbn	-	-	ko:K03466,ko:K07058	-	-	-	-	ko00000,ko03036	3.A.12	-	-	Virul_fac_BrkB
MMS3_k127_1370954_2	1380394.JADL01000002_gene1112	8.167e-94	315.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,2JPQ8@204441|Rhodospirillales	204441|Rhodospirillales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
MMS3_k127_1370954_0	479434.Sthe_3245	9.389e-263	832.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	2|Bacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
MMS3_k127_1370954_1	479434.Sthe_3254	8.632e-159	520.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi,27XID@189775|Thermomicrobia	189775|Thermomicrobia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_1371321_0	1200792.AKYF01000021_gene5322	6.888e-155	502.0	COG1506@1|root,COG1506@2|Bacteria,1VSK9@1239|Firmicutes,4HU6U@91061|Bacilli,2727N@186822|Paenibacillaceae	91061|Bacilli	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
MMS3_k127_1371321_3	479434.Sthe_3272	9.548e-33	132.0	COG1848@1|root,COG1848@2|Bacteria,2G9NX@200795|Chloroflexi	200795|Chloroflexi	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_1371321_1	1123237.Salmuc_03678	1.25e-103	359.0	COG2234@1|root,COG2234@2|Bacteria,1PF4S@1224|Proteobacteria,2U3SU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_1371321_2	105420.BBPO01000031_gene6641	1.824e-85	291.0	COG0580@1|root,COG0580@2|Bacteria,2IG6C@201174|Actinobacteria,2NIZF@228398|Streptacidiphilus	201174|Actinobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
MMS3_k127_1393960_5	1295642.H839_09323	3.971e-54	192.0	COG1235@1|root,COG1235@2|Bacteria,1U5T1@1239|Firmicutes,4I67K@91061|Bacilli,1WHQA@129337|Geobacillus	91061|Bacilli	S	May be involved in the transport of PQQ or its precursor to the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1393960_6	479434.Sthe_2337	1.704e-51	186.0	2A4R7@1|root,30TCK@2|Bacteria,2GBB1@200795|Chloroflexi,27YKY@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1393960_3	479434.Sthe_2338	1.767e-65	231.0	COG2364@1|root,COG2364@2|Bacteria,2G742@200795|Chloroflexi,27Z7B@189775|Thermomicrobia	189775|Thermomicrobia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1393960_7	479434.Sthe_2208	1.18e-50	184.0	COG2020@1|root,COG2020@2|Bacteria,2G9XH@200795|Chloroflexi,27ZA9@189775|Thermomicrobia	189775|Thermomicrobia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMS3_k127_1393960_4	479434.Sthe_2340	1.021e-62	220.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,27YFN@189775|Thermomicrobia	189775|Thermomicrobia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMS3_k127_1393960_8	479434.Sthe_2342	6.504e-50	184.0	2B6EA@1|root,31ZC5@2|Bacteria,2GA1T@200795|Chloroflexi,27YPK@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1393960_0	247490.KSU1_C1036	0.0	1094.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2IYJS@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS3_k127_1393960_2	479434.Sthe_2343	2.266e-128	422.0	COG0477@1|root,COG2814@2|Bacteria,2G9NF@200795|Chloroflexi,27Y14@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1393960_1	479434.Sthe_2344	6.368e-159	506.0	COG2008@1|root,COG2008@2|Bacteria,2G7UV@200795|Chloroflexi,27XVE@189775|Thermomicrobia	189775|Thermomicrobia	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
MMS3_k127_1405031_1	292459.STH1305	4.537e-128	430.0	28HBW@1|root,2Z7NV@2|Bacteria,1TSAK@1239|Firmicutes,24BU6@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1998
MMS3_k127_1405031_0	292459.STH1306	8.655e-257	831.0	COG1061@1|root,COG1061@2|Bacteria,1TPWX@1239|Firmicutes,24962@186801|Clostridia	186801|Clostridia	KL	PFAM helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
MMS3_k127_1405031_2	1437882.AZRU01000010_gene570	1.591e-29	122.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1T9QH@1236|Gammaproteobacteria,1YGZ8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
MMS3_k127_1408180_1	234267.Acid_7156	3.178e-53	193.0	COG3882@1|root,COG3882@2|Bacteria	2|Bacteria	Q	phosphopantetheine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1408180_2	1047013.AQSP01000144_gene880	2.243e-12	70.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
MMS3_k127_1408180_0	1340434.AXVA01000016_gene764	1.121e-61	225.0	COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,1ZBDC@1386|Bacillus	91061|Bacilli	E	Acetylornithine deacetylase	yodQ	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_1409428_5	1382306.JNIM01000001_gene3594	1.45e-156	514.0	COG4987@1|root,COG4987@2|Bacteria,2GA7U@200795|Chloroflexi	200795|Chloroflexi	V	TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	-	-	-	ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
MMS3_k127_1409428_3	1382306.JNIM01000001_gene3595	1.961e-167	543.0	COG4988@1|root,COG4988@2|Bacteria,2G7JB@200795|Chloroflexi	200795|Chloroflexi	CO	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	-	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
MMS3_k127_1409428_7	42256.RradSPS_3067	3.24e-145	467.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4CQE5@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
MMS3_k127_1409428_1	42256.RradSPS_3068	4.249e-207	652.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4CPFN@84995|Rubrobacteria	84995|Rubrobacteria	C	ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
MMS3_k127_1409428_9	485913.Krac_1223	3.598e-100	336.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1409428_8	398525.KB900701_gene298	3.522e-124	406.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2TYHX@28211|Alphaproteobacteria,3JTNQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
MMS3_k127_1409428_6	1120971.AUCA01000029_gene222	6.283e-150	485.0	COG0508@1|root,COG0508@2|Bacteria,1TP3C@1239|Firmicutes,4HBVM@91061|Bacilli,2793W@186823|Alicyclobacillaceae	91061|Bacilli	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	odhB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_1409428_0	479434.Sthe_2058	0.0	1294.0	COG0567@1|root,COG0567@2|Bacteria,2G638@200795|Chloroflexi,27XYT@189775|Thermomicrobia	189775|Thermomicrobia	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
MMS3_k127_1409428_2	479434.Sthe_2059	2.333e-176	561.0	COG0644@1|root,COG0644@2|Bacteria,2G8CW@200795|Chloroflexi,27XII@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
MMS3_k127_1409428_13	370438.PTH_1709	7.844e-14	74.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,24V8A@186801|Clostridia,262T4@186807|Peptococcaceae	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_1409428_11	2002.JOEQ01000004_gene2999	9.207e-48	179.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EIFM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
MMS3_k127_1409428_12	1183438.GKIL_3416	9.04e-24	117.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1G31U@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA_3,PAS_9
MMS3_k127_1409428_10	1121946.AUAX01000008_gene7359	1.701e-82	297.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4D9QB@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156,Rhomboid
MMS3_k127_1409428_4	479434.Sthe_2062	2.653e-166	535.0	COG2239@1|root,COG2239@2|Bacteria,2G6H7@200795|Chloroflexi,27Y1H@189775|Thermomicrobia	189775|Thermomicrobia	P	MgtE intracellular N domain	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
MMS3_k127_1443775_0	479434.Sthe_0947	3.65e-188	593.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi,27Y49@189775|Thermomicrobia	189775|Thermomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA,R3H
MMS3_k127_1443775_1	479434.Sthe_0946	5.377e-77	273.0	2A40S@1|root,30SJA@2|Bacteria,2GADS@200795|Chloroflexi,27YNA@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1443775_2	309801.trd_0204	6.568e-49	175.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,27XUN@189775|Thermomicrobia	189775|Thermomicrobia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
MMS3_k127_1451153_7	479434.Sthe_1424	5.462e-55	198.0	COG0712@1|root,COG0712@2|Bacteria,2G78B@200795|Chloroflexi,27YHC@189775|Thermomicrobia	189775|Thermomicrobia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
MMS3_k127_1451153_6	479434.Sthe_1425	1.215e-57	204.0	COG0711@1|root,COG0711@2|Bacteria,2G76T@200795|Chloroflexi,27YGB@189775|Thermomicrobia	189775|Thermomicrobia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
MMS3_k127_1451153_11	309801.trd_1233	6.676e-24	104.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi,27YPV@189775|Thermomicrobia	189775|Thermomicrobia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
MMS3_k127_1451153_2	479434.Sthe_1427	5.183e-99	330.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi,27XY1@189775|Thermomicrobia	189775|Thermomicrobia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
MMS3_k127_1451153_12	479434.Sthe_1428	1.919e-22	99.0	2A4RD@1|root,30TCS@2|Bacteria,2GBB6@200795|Chloroflexi,27YMN@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
MMS3_k127_1451153_1	479434.Sthe_1429	1.958e-289	896.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,27XSS@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
MMS3_k127_1451153_4	479434.Sthe_1430	4.845e-89	299.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi,27Y80@189775|Thermomicrobia	189775|Thermomicrobia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
MMS3_k127_1451153_10	479434.Sthe_1431	1.652e-24	109.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi,27Z8T@189775|Thermomicrobia	189775|Thermomicrobia	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	-
MMS3_k127_1451153_9	479434.Sthe_1432	2.086e-50	188.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,27YM4@189775|Thermomicrobia	189775|Thermomicrobia	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
MMS3_k127_1451153_8	479434.Sthe_1433	3.532e-53	196.0	COG1434@1|root,COG1434@2|Bacteria,2G996@200795|Chloroflexi,27YFA@189775|Thermomicrobia	189775|Thermomicrobia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
MMS3_k127_1451153_3	891968.Anamo_1665	3.835e-90	310.0	COG0436@1|root,COG0436@2|Bacteria,3TAQC@508458|Synergistetes	508458|Synergistetes	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
MMS3_k127_1451153_5	479434.Sthe_3127	1.559e-81	279.0	COG0745@1|root,COG0745@2|Bacteria,2G8ZD@200795|Chloroflexi,27Z5Y@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1451153_0	479434.Sthe_1438	0.0	1089.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,27XYD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
MMS3_k127_1472040_1	479434.Sthe_2525	2.583e-133	431.0	COG0277@1|root,COG0277@2|Bacteria,2G885@200795|Chloroflexi,27Z0Z@189775|Thermomicrobia	189775|Thermomicrobia	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
MMS3_k127_1472040_0	479434.Sthe_2526	1.008e-221	713.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
MMS3_k127_1483954_1	479434.Sthe_0246	2.015e-57	212.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
MMS3_k127_1483954_0	479434.Sthe_0248	2.932e-136	441.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi,27XVV@189775|Thermomicrobia	189775|Thermomicrobia	E	NeuB family	-	-	-	-	-	-	-	-	-	-	-	-	DAHP_synth_1
MMS3_k127_1498819_1	251221.35214089	1.052e-57	217.0	COG1228@1|root,COG1228@2|Bacteria,1G3PN@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_1498819_0	479434.Sthe_2596	1.437e-246	774.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	2|Bacteria	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_1498819_2	264732.Moth_0212	1.11e-39	156.0	COG4126@1|root,COG4126@2|Bacteria,1TT35@1239|Firmicutes,24KAI@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K14591	-	-	-	-	ko00000	-	-	-	AroM
MMS3_k127_1499637_2	479434.Sthe_1323	5.108e-116	382.0	COG0438@1|root,COG0438@2|Bacteria,2G6Z9@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
MMS3_k127_1499637_1	479434.Sthe_1324	1.348e-147	474.0	COG0438@1|root,COG0438@2|Bacteria,2G7XU@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_1499637_4	479434.Sthe_1325	6.364e-35	137.0	2EU3R@1|root,33MKI@2|Bacteria,2G9PI@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1499637_0	479434.Sthe_1326	3.366e-158	512.0	COG0438@1|root,COG0438@2|Bacteria,2G82G@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
MMS3_k127_1499637_3	479434.Sthe_1327	1.19e-46	178.0	COG4235@1|root,COG4235@2|Bacteria,2GBF9@200795|Chloroflexi,27ZA7@189775|Thermomicrobia	189775|Thermomicrobia	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1515338_3	479434.Sthe_1347	9.515e-122	400.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_1515338_4	479434.Sthe_1348	1.092e-75	263.0	COG0235@1|root,COG0235@2|Bacteria,2G9E9@200795|Chloroflexi,27YQX@189775|Thermomicrobia	189775|Thermomicrobia	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
MMS3_k127_1515338_2	479434.Sthe_1349	1.088e-124	407.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi,27XSQ@189775|Thermomicrobia	189775|Thermomicrobia	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
MMS3_k127_1515338_6	479434.Sthe_1350	7.044e-43	160.0	2A400@1|root,30SIG@2|Bacteria,2GB4C@200795|Chloroflexi,27YMC@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1515338_1	479434.Sthe_3289	4.598e-138	447.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
MMS3_k127_1515338_0	330084.JNYZ01000046_gene1927	8.285e-173	567.0	COG1042@1|root,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4E8NX@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA binding domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
MMS3_k127_1515338_5	479434.Sthe_0530	3.144e-59	209.0	COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.8	ko:K00255,ko:K11731	ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754,R08089	RC00052,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1531210_7	1296416.JACB01000063_gene2002	0.0005723	46.0	2DQVQ@1|root,338YQ@2|Bacteria,4NWGI@976|Bacteroidetes,1IIE8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1531210_4	479434.Sthe_0698	1.991e-116	380.0	COG0413@1|root,COG0413@2|Bacteria,2G5TQ@200795|Chloroflexi,27XR8@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
MMS3_k127_1531210_1	479434.Sthe_0695	2.041e-188	600.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi,27XPD@189775|Thermomicrobia	189775|Thermomicrobia	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
MMS3_k127_1531210_3	316274.Haur_0014	2.284e-136	456.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi,3753F@32061|Chloroflexia	32061|Chloroflexia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
MMS3_k127_1531210_2	479434.Sthe_0415	1.676e-161	514.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi,27XIJ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
MMS3_k127_1531210_0	479434.Sthe_0416	8.62e-303	937.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi,27Y2A@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
MMS3_k127_1531210_5	479434.Sthe_0417	3.307e-72	249.0	COG0009@1|root,COG0009@2|Bacteria,2G673@200795|Chloroflexi,27Y7A@189775|Thermomicrobia	189775|Thermomicrobia	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
MMS3_k127_1531210_6	479434.Sthe_0422	1.397e-50	184.0	2ETJ3@1|root,33M2W@2|Bacteria,2G7IK@200795|Chloroflexi,27YKN@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1533204_2	1118054.CAGW01000024_gene451	3.955e-95	320.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,26SYE@186822|Paenibacillaceae	91061|Bacilli	E	peptidase M20	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_1533204_1	479434.Sthe_3157	1.612e-117	382.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_1533204_4	479434.Sthe_0204	7.85e-84	299.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi,27XYA@189775|Thermomicrobia	200795|Chloroflexi	M	SMART Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
MMS3_k127_1533204_9	1157490.EL26_08395	5.635e-42	163.0	COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,4HBYK@91061|Bacilli	91061|Bacilli	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
MMS3_k127_1533204_0	1121952.ATXT01000016_gene744	4.295e-174	566.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4FQYK@85023|Microbacteriaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_1533204_5	469615.FGAG_00763	3.589e-70	253.0	COG1960@1|root,COG1960@2|Bacteria,378TZ@32066|Fusobacteria	32066|Fusobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1533204_3	469383.Cwoe_5051	2.4e-85	297.0	COG0438@1|root,COG4833@1|root,COG0438@2|Bacteria,COG4833@2|Bacteria	2|Bacteria	G	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_76,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_1533204_8	76114.ebA4292	6.849e-43	181.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VYV5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
MMS3_k127_1533204_6	1463909.KL585946_gene1453	1.131e-65	233.0	COG0463@1|root,COG1215@1|root,COG3774@1|root,COG0463@2|Bacteria,COG1215@2|Bacteria,COG3774@2|Bacteria,2IC0M@201174|Actinobacteria	201174|Actinobacteria	M	Anp1	-	-	-	-	-	-	-	-	-	-	-	-	Anp1,Gly_transf_sug,Glycos_transf_2
MMS3_k127_153465_2	479434.Sthe_2942	5.308e-81	276.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi,27YB5@189775|Thermomicrobia	189775|Thermomicrobia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMS3_k127_153465_1	479434.Sthe_2943	5.52e-131	423.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi,27XEY@189775|Thermomicrobia	189775|Thermomicrobia	HJ	RimK-like ATP-grasp domain	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
MMS3_k127_153465_4	883126.HMPREF9710_04788	0.0002175	52.0	COG3861@1|root,COG3861@2|Bacteria	2|Bacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_153465_0	479434.Sthe_2949	0.0	1096.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2G665@200795|Chloroflexi,27XZR@189775|Thermomicrobia	189775|Thermomicrobia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,LUD_dom
MMS3_k127_153465_3	1192034.CAP_1358	8.104e-21	104.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
MMS3_k127_1534879_3	326427.Cagg_2765	5.188e-05	48.0	COG0520@1|root,COG0520@2|Bacteria,2G7N0@200795|Chloroflexi,377HP@32061|Chloroflexia	32061|Chloroflexia	H	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_1534879_1	696281.Desru_3258	1.574e-51	188.0	COG0431@1|root,COG0431@2|Bacteria,1V41C@1239|Firmicutes,25BUB@186801|Clostridia,2674C@186807|Peptococcaceae	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
MMS3_k127_1534879_0	1382356.JQMP01000003_gene1694	1.641e-71	254.0	COG2514@1|root,COG2514@2|Bacteria,2G6MQ@200795|Chloroflexi,27YFG@189775|Thermomicrobia	189775|Thermomicrobia	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
MMS3_k127_1534879_2	1218173.BALCAV_0204520	7.36e-18	88.0	COG0454@1|root,COG0456@2|Bacteria,1VM6C@1239|Firmicutes,4IKX6@91061|Bacilli,1ZI62@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
MMS3_k127_1536346_5	1382356.JQMP01000003_gene2337	7.527e-13	71.0	COG3858@1|root,COG3858@2|Bacteria,2G7HP@200795|Chloroflexi,27XZM@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycoside hydrolase, family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
MMS3_k127_1536346_1	749222.Nitsa_0869	5.799e-74	255.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,42RP4@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
MMS3_k127_1536346_2	309801.trd_A0626	8.747e-41	154.0	COG1371@1|root,COG1371@2|Bacteria,2GA47@200795|Chloroflexi,27Z6Y@189775|Thermomicrobia	189775|Thermomicrobia	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
MMS3_k127_1536346_0	479434.Sthe_3251	5.346e-190	605.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi,27XP1@189775|Thermomicrobia	189775|Thermomicrobia	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
MMS3_k127_1536346_3	309801.trd_0947	1.757e-20	97.0	2A6MH@1|root,30VFB@2|Bacteria,2GB67@200795|Chloroflexi,27YQ6@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1536346_4	555088.DealDRAFT_1263	4.216e-19	98.0	COG1377@1|root,COG1377@2|Bacteria	2|Bacteria	N	bacterial-type flagellum assembly	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
MMS3_k127_1551336_3	479434.Sthe_1966	5.181e-24	102.0	COG3634@1|root,COG3634@2|Bacteria,2GBT2@200795|Chloroflexi,27Z89@189775|Thermomicrobia	189775|Thermomicrobia	O	alkyl hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1551336_1	479434.Sthe_1966	1.001e-64	225.0	COG3634@1|root,COG3634@2|Bacteria,2GBT2@200795|Chloroflexi,27Z89@189775|Thermomicrobia	189775|Thermomicrobia	O	alkyl hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1551336_0	479434.Sthe_1965	8.215e-152	485.0	COG1801@1|root,COG1801@2|Bacteria,2G721@200795|Chloroflexi,27XQG@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMS3_k127_1551336_2	1121945.ATXS01000003_gene1551	3.926e-46	175.0	COG1397@1|root,arCOG04448@2157|Archaea,2XV15@28890|Euryarchaeota,23TFB@183963|Halobacteria	183963|Halobacteria	O	ADP-ribosyl-(Dinitrogen reductase) hydrolase	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
MMS3_k127_155733_1	479434.Sthe_2696	1.15e-226	711.0	COG0114@1|root,COG0114@2|Bacteria,2GBNI@200795|Chloroflexi	200795|Chloroflexi	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
MMS3_k127_155733_9	1304865.JAGF01000001_gene1075	8.489e-80	274.0	COG0451@1|root,COG0457@1|root,COG0451@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	4.1.1.35	ko:K00754,ko:K08678,ko:K13613	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	GT4	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,VKOR,ketoacyl-synt
MMS3_k127_155733_3	479434.Sthe_2746	5.883e-145	466.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	nit2	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
MMS3_k127_155733_4	28444.JODQ01000001_gene2596	2.274e-133	465.0	COG0577@1|root,COG0577@2|Bacteria,2H997@201174|Actinobacteria,4EGB7@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
MMS3_k127_155733_11	649831.L083_4494	3.436e-48	198.0	COG0577@1|root,COG0577@2|Bacteria,2GNEX@201174|Actinobacteria,4DCK8@85008|Micromonosporales	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
MMS3_k127_155733_6	1304865.JAGF01000001_gene2550	2.373e-120	394.0	COG1136@1|root,COG1136@2|Bacteria,2GIV7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_155733_8	263358.VAB18032_20530	1.23e-86	299.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4D9QK@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_155733_14	479434.Sthe_2194	6.394e-16	84.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,T4_deiodinase
MMS3_k127_155733_10	525904.Tter_2362	5.422e-78	271.0	COG0785@1|root,COG0785@2|Bacteria,2NRAI@2323|unclassified Bacteria	2|Bacteria	O	PFAM Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
MMS3_k127_155733_13	1120985.AUMI01000011_gene254	1.574e-16	87.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4H5X0@909932|Negativicutes	909932|Negativicutes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
MMS3_k127_155733_0	479434.Sthe_0099	0.0	1038.0	COG0243@1|root,COG0243@2|Bacteria,2GABT@200795|Chloroflexi,27Z9X@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMS3_k127_155733_15	714083.JH370377_gene609	2.57e-07	62.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4FMK8@85023|Microbacteriaceae	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156
MMS3_k127_155733_2	1382356.JQMP01000001_gene733	7.954e-220	711.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,2G6KJ@200795|Chloroflexi,27YNQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156,LPG_synthase_TM
MMS3_k127_155733_5	479434.Sthe_3075	1.857e-131	450.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
MMS3_k127_155733_7	479434.Sthe_1742	1.398e-98	325.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1563964_9	479434.Sthe_0465	3.247e-09	61.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi,27Y19@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_1563964_4	1382356.JQMP01000003_gene2139	7.698e-157	502.0	COG0686@1|root,COG0686@2|Bacteria,2G68X@200795|Chloroflexi,27YU4@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
MMS3_k127_1563964_2	479434.Sthe_0464	2.637e-160	516.0	COG0750@1|root,COG0750@2|Bacteria,2G6HV@200795|Chloroflexi,27XS5@189775|Thermomicrobia	189775|Thermomicrobia	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
MMS3_k127_1563964_1	479434.Sthe_0463	5.882e-206	646.0	COG0821@1|root,COG0821@2|Bacteria,2G5SC@200795|Chloroflexi,27XZE@189775|Thermomicrobia	189775|Thermomicrobia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
MMS3_k127_1563964_8	1148.1653142	3.118e-53	195.0	COG1878@1|root,COG1878@2|Bacteria,1G60Q@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
MMS3_k127_1563964_6	479434.Sthe_0462	2.408e-103	345.0	COG0524@1|root,COG0524@2|Bacteria,2G7CJ@200795|Chloroflexi,27Y74@189775|Thermomicrobia	189775|Thermomicrobia	G	belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
MMS3_k127_1563964_3	479434.Sthe_0461	1.332e-159	511.0	COG1600@1|root,COG1600@2|Bacteria,2G6A0@200795|Chloroflexi,27XIW@189775|Thermomicrobia	189775|Thermomicrobia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
MMS3_k127_1563964_7	479434.Sthe_0460	3.15e-100	332.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi,27Y5M@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
MMS3_k127_1563964_5	309801.trd_1063	7.344e-133	434.0	COG1363@1|root,COG1363@2|Bacteria,2GAAU@200795|Chloroflexi,27YY7@189775|Thermomicrobia	189775|Thermomicrobia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
MMS3_k127_1563964_0	479434.Sthe_0459	9.622e-305	946.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi,27XJI@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_1566523_3	93220.LV28_05975	2.105e-14	76.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2VKN4@28216|Betaproteobacteria,1K579@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
MMS3_k127_1566523_0	392499.Swit_2492	1.092e-204	648.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K3V8@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-dependent synthetase and ligase	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_1566523_1	864069.MicloDRAFT_00024060	6.249e-121	402.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2TSSE@28211|Alphaproteobacteria,1JSA3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM Malonyl-CoA decarboxylase	matA	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
MMS3_k127_1566523_2	426355.Mrad2831_0165	4.237e-40	153.0	COG1802@1|root,COG1802@2|Bacteria,1RBIC@1224|Proteobacteria,2TSVQ@28211|Alphaproteobacteria,1JRUC@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	PFAM regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS3_k127_1567835_7	479434.Sthe_1672	5.145e-13	79.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
MMS3_k127_1567835_6	479434.Sthe_1673	2.594e-33	133.0	COG1983@1|root,COG1983@2|Bacteria,2G9IZ@200795|Chloroflexi	200795|Chloroflexi	KT	PFAM PspC domain protein	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
MMS3_k127_1567835_1	479434.Sthe_1674	1.249e-184	591.0	COG0124@1|root,COG0124@2|Bacteria,2G6CX@200795|Chloroflexi,27Y1E@189775|Thermomicrobia	189775|Thermomicrobia	J	Histidyl-tRNA synthetase	-	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
MMS3_k127_1567835_4	1128421.JAGA01000001_gene2406	9.607e-101	339.0	COG0040@1|root,COG0040@2|Bacteria	2|Bacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
MMS3_k127_1567835_0	479434.Sthe_1676	2.265e-198	627.0	COG0141@1|root,COG0141@2|Bacteria,2G5KP@200795|Chloroflexi,27XKM@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
MMS3_k127_1567835_5	479434.Sthe_1680	2.268e-74	254.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi,27YFW@189775|Thermomicrobia	189775|Thermomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
MMS3_k127_1567835_3	479434.Sthe_1681	1.805e-103	344.0	COG2159@1|root,COG2159@2|Bacteria,2G6CW@200795|Chloroflexi,27Y4A@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS3_k127_1567835_2	479434.Sthe_1682	9.738e-124	402.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi,27XZK@189775|Thermomicrobia	189775|Thermomicrobia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C
MMS3_k127_1572810_9	479434.Sthe_2506	4.058e-89	310.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_1572810_14	314230.DSM3645_23995	5.413e-12	72.0	COG1846@1|root,COG1846@2|Bacteria,2J3AR@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator, MarR family	-	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
MMS3_k127_1572810_1	479434.Sthe_1612	0.0	1410.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,27Y20@189775|Thermomicrobia	189775|Thermomicrobia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
MMS3_k127_1572810_11	479434.Sthe_1613	5.991e-71	248.0	COG2094@1|root,COG2094@2|Bacteria,2G77D@200795|Chloroflexi,27Z70@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
MMS3_k127_1572810_2	479434.Sthe_1614	5.709e-229	723.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi,27XXX@189775|Thermomicrobia	189775|Thermomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	-	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
MMS3_k127_1572810_6	479434.Sthe_1615	8.625e-119	385.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1572810_10	1382356.JQMP01000004_gene364	1.184e-72	258.0	COG4585@1|root,COG4585@2|Bacteria,2G8Y1@200795|Chloroflexi,27YD5@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
MMS3_k127_1572810_12	479434.Sthe_1618	2.594e-66	233.0	COG4126@1|root,COG4126@2|Bacteria	2|Bacteria	E	flavin adenine dinucleotide binding	aroM	-	-	ko:K14591	-	-	-	-	ko00000	-	-	-	AroM
MMS3_k127_1572810_7	479434.Sthe_1620	4.782e-105	352.0	COG0463@1|root,COG0463@2|Bacteria,2G6GT@200795|Chloroflexi,27XWJ@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1572810_0	479434.Sthe_1621	0.0	1623.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,27XGQ@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
MMS3_k127_1572810_5	479434.Sthe_2168	2.77e-174	554.0	COG0665@1|root,COG0665@2|Bacteria,2GBER@200795|Chloroflexi,27Z6Q@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_1572810_3	479434.Sthe_2607	5.99e-228	713.0	COG1032@1|root,COG1032@2|Bacteria,2G7MA@200795|Chloroflexi,27Y05@189775|Thermomicrobia	189775|Thermomicrobia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMS3_k127_1572810_8	479434.Sthe_1626	2.655e-93	319.0	COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi,27Y84@189775|Thermomicrobia	189775|Thermomicrobia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
MMS3_k127_1572810_4	479434.Sthe_1627	1.654e-212	668.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi,27Y3M@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
MMS3_k127_1572810_13	1128421.JAGA01000002_gene910	1.883e-39	152.0	2DQ8Q@1|root,335AV@2|Bacteria,2NQY5@2323|unclassified Bacteria	2|Bacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_1574338_1	479434.Sthe_1236	8.24e-74	254.0	COG2423@1|root,COG2423@2|Bacteria,2G6BQ@200795|Chloroflexi,27XIZ@189775|Thermomicrobia	189775|Thermomicrobia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
MMS3_k127_1574338_0	479434.Sthe_1238	6.3e-294	910.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi,27Y30@189775|Thermomicrobia	189775|Thermomicrobia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S
MMS3_k127_1574338_2	479434.Sthe_1239	1.363e-70	246.0	COG1905@1|root,COG1905@2|Bacteria,2G6Q5@200795|Chloroflexi,27Y9K@189775|Thermomicrobia	189775|Thermomicrobia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMS3_k127_1574338_3	479434.Sthe_1240	1.18e-42	161.0	2DRW3@1|root,33DCW@2|Bacteria,2G7E0@200795|Chloroflexi,27YHK@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
MMS3_k127_1574338_5	479434.Sthe_1241	2.283e-24	105.0	COG5662@1|root,COG5662@2|Bacteria,2GA5X@200795|Chloroflexi,27ZCC@189775|Thermomicrobia	189775|Thermomicrobia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
MMS3_k127_1574338_4	479434.Sthe_1242	1.189e-42	158.0	COG1595@1|root,COG1595@2|Bacteria,2G90X@200795|Chloroflexi,27Z65@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1575532_6	867845.KI911784_gene1698	2.918e-57	206.0	COG1028@1|root,COG1028@2|Bacteria,2GAK3@200795|Chloroflexi,3774Y@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1575532_7	479434.Sthe_3159	1.312e-55	196.0	COG2440@1|root,COG2440@2|Bacteria,2G7FT@200795|Chloroflexi,27YFB@189775|Thermomicrobia	189775|Thermomicrobia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	-	ko:K03855	-	-	-	-	ko00000	-	-	-	ETF_QO
MMS3_k127_1575532_10	68260.JOAY01000018_gene3286	1.154e-07	60.0	COG3703@1|root,COG3703@2|Bacteria,2GJM9@201174|Actinobacteria	201174|Actinobacteria	P	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2
MMS3_k127_1575532_4	479434.Sthe_3160	1.36e-72	248.0	COG3411@1|root,COG3411@2|Bacteria,2GA0H@200795|Chloroflexi,27YC7@189775|Thermomicrobia	189775|Thermomicrobia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1575532_0	479434.Sthe_3161	4.692e-150	481.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi,27XU9@189775|Thermomicrobia	189775|Thermomicrobia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
MMS3_k127_1575532_3	351160.LRC130	2.746e-82	280.0	COG4912@1|root,arCOG11010@2157|Archaea,2XWKG@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
MMS3_k127_1575532_5	479434.Sthe_3243	2.04e-63	224.0	COG1011@1|root,COG1011@2|Bacteria,2G7B3@200795|Chloroflexi,27YGG@189775|Thermomicrobia	189775|Thermomicrobia	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMS3_k127_1575532_1	479434.Sthe_3302	3.804e-146	467.0	COG2362@1|root,COG2362@2|Bacteria,2G8M4@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M55 D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
MMS3_k127_1575532_9	290397.Adeh_0738	2.212e-49	190.0	COG0122@1|root,COG0122@2|Bacteria,1P0FP@1224|Proteobacteria	1224|Proteobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_1575532_2	479434.Sthe_3166	4.767e-130	421.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi,27YXH@189775|Thermomicrobia	189775|Thermomicrobia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	-	-	-	-	-	-	-	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
MMS3_k127_1575532_8	479434.Sthe_3165	5.108e-51	183.0	29I5S@1|root,3052X@2|Bacteria,2GB9P@200795|Chloroflexi,27YD0@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1580936_14	479434.Sthe_0035	9.449e-22	98.0	2A4R9@1|root,30TCN@2|Bacteria,2GBB3@200795|Chloroflexi,27YM7@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1580936_6	580327.Tthe_0829	1.397e-75	265.0	COG5459@1|root,COG5459@2|Bacteria,1V30U@1239|Firmicutes,24GFC@186801|Clostridia	186801|Clostridia	J	PFAM Ribosomal	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
MMS3_k127_1580936_0	479434.Sthe_2054	1.006e-234	736.0	COG0028@1|root,COG0028@2|Bacteria,2G810@200795|Chloroflexi,27XX3@189775|Thermomicrobia	189775|Thermomicrobia	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_1580936_9	479434.Sthe_0038	4.46e-55	200.0	COG1999@1|root,COG1999@2|Bacteria,2GAE4@200795|Chloroflexi,27YPG@189775|Thermomicrobia	189775|Thermomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
MMS3_k127_1580936_7	479434.Sthe_0060	9.166e-66	228.0	29TQQ@1|root,30EYV@2|Bacteria,2GA0U@200795|Chloroflexi,27YGE@189775|Thermomicrobia	189775|Thermomicrobia	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
MMS3_k127_1580936_8	479434.Sthe_2072	2.562e-56	204.0	COG1825@1|root,COG1825@2|Bacteria,2G7A4@200795|Chloroflexi,27YEB@189775|Thermomicrobia	189775|Thermomicrobia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
MMS3_k127_1580936_11	479434.Sthe_2073	1.908e-42	163.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	yfiV	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_1580936_10	1382356.JQMP01000003_gene2050	2.563e-50	185.0	COG1309@1|root,COG1309@2|Bacteria,2G8XR@200795|Chloroflexi,27Z5B@189775|Thermomicrobia	189775|Thermomicrobia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1580936_12	234267.Acid_0571	8.341e-33	130.0	COG0346@1|root,COG0346@2|Bacteria,3Y85T@57723|Acidobacteria	57723|Acidobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_1580936_3	309801.trd_A0511	1.358e-141	454.0	COG0388@1|root,COG0388@2|Bacteria,2G6KM@200795|Chloroflexi,27XTA@189775|Thermomicrobia	189775|Thermomicrobia	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
MMS3_k127_1580936_2	1382356.JQMP01000003_gene2033	2.188e-201	632.0	COG1804@1|root,COG1804@2|Bacteria,2GABR@200795|Chloroflexi,27XHH@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
MMS3_k127_1580936_4	479434.Sthe_0200	9.58e-110	358.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi,27XVP@189775|Thermomicrobia	189775|Thermomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1580936_5	479434.Sthe_0199	2.083e-100	342.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G90K@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
MMS3_k127_1580936_1	479434.Sthe_0198	2.718e-223	716.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2GA17@200795|Chloroflexi,27YIU@189775|Thermomicrobia	189775|Thermomicrobia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1582248_8	649638.Trad_2578	2.29e-25	112.0	COG4977@1|root,COG4977@2|Bacteria,1WMU4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
MMS3_k127_1582248_1	479434.Sthe_2131	2.019e-182	580.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27XZ4@189775|Thermomicrobia	200795|Chloroflexi	E	Cys/Met metabolism PLP-dependent enzyme	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_1582248_0	1205753.A989_09913	7.021e-255	809.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1X3BC@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
MMS3_k127_1582248_7	479434.Sthe_2129	7.043e-44	162.0	COG1733@1|root,COG1733@2|Bacteria,2G792@200795|Chloroflexi,27YJG@189775|Thermomicrobia	189775|Thermomicrobia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
MMS3_k127_1582248_6	479434.Sthe_2128	2.158e-62	220.0	COG2353@1|root,COG2353@2|Bacteria,2G6G9@200795|Chloroflexi,27Y8W@189775|Thermomicrobia	189775|Thermomicrobia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
MMS3_k127_1582248_5	2002.JOEQ01000054_gene435	4.501e-63	231.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria,4EPCZ@85012|Streptosporangiales	201174|Actinobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
MMS3_k127_1582248_2	485913.Krac_2134	2.51e-128	418.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
MMS3_k127_1582248_4	485913.Krac_7021	6.408e-75	265.0	COG4099@1|root,COG4099@2|Bacteria	2|Bacteria	F	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Esterase,Esterase_phd,Peptidase_S9
MMS3_k127_1582248_3	479434.Sthe_2395	9.254e-110	359.0	COG2120@1|root,COG2120@2|Bacteria,2GB97@200795|Chloroflexi,27XJ6@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_1582248_9	105425.BBPL01000100_gene1224	4.307e-22	98.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria,2NJ6C@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
MMS3_k127_1582546_12	402626.Rpic_2197	0.0003039	45.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2VIQT@28216|Betaproteobacteria,1JZSR@119060|Burkholderiaceae	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1582546_8	479434.Sthe_2904	1.189e-100	335.0	COG2086@1|root,COG2086@2|Bacteria,2G72U@200795|Chloroflexi,27XPK@189775|Thermomicrobia	200795|Chloroflexi	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
MMS3_k127_1582546_7	479434.Sthe_2903	3.316e-127	414.0	COG2025@1|root,COG2025@2|Bacteria,2G6PP@200795|Chloroflexi,27XU4@189775|Thermomicrobia	189775|Thermomicrobia	C	Electron transfer flavoprotein	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
MMS3_k127_1582546_0	479434.Sthe_2901	0.0	1078.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2G5X6@200795|Chloroflexi,27YVD@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
MMS3_k127_1582546_9	479434.Sthe_1939	4.914e-58	211.0	COG0491@1|root,COG0491@2|Bacteria,2G8W8@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_1582546_5	479434.Sthe_2684	8.451e-168	538.0	COG0477@1|root,COG2814@2|Bacteria,2G8W5@200795|Chloroflexi	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1582546_10	1123504.JQKD01000004_gene5005	3.663e-32	130.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_1582546_6	479434.Sthe_2924	2.899e-151	483.0	COG2070@1|root,COG2070@2|Bacteria	2|Bacteria	S	nitronate monooxygenase activity	fabK	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
MMS3_k127_1582546_1	479434.Sthe_2923	0.0	1046.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,27YVW@189775|Thermomicrobia	189775|Thermomicrobia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
MMS3_k127_1582546_4	479434.Sthe_2922	1.05e-185	587.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,27YXA@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_1582546_2	479434.Sthe_2921	5.456e-260	812.0	COG1960@1|root,COG1960@2|Bacteria,2G7UB@200795|Chloroflexi	200795|Chloroflexi	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1582546_3	1382356.JQMP01000003_gene1838	4.889e-232	732.0	COG0318@1|root,COG0318@2|Bacteria,2G5XA@200795|Chloroflexi,27YWU@189775|Thermomicrobia	189775|Thermomicrobia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_1582546_11	1124991.MU9_442	3.111e-16	81.0	2EER1@1|root,338IS@2|Bacteria,1NG14@1224|Proteobacteria,1SFRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_158504_2	1128421.JAGA01000002_gene1057	3.463e-56	203.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
MMS3_k127_158504_1	765420.OSCT_2757	4.81e-68	245.0	COG1300@1|root,COG1300@2|Bacteria,2G8HV@200795|Chloroflexi,37546@32061|Chloroflexia	32061|Chloroflexia	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
MMS3_k127_158504_3	1128421.JAGA01000001_gene2051	3.554e-49	186.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMS3_k127_158504_0	1169161.KB897738_gene2537	2.416e-71	250.0	COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria	201174|Actinobacteria	S	Creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_1588081_1	479434.Sthe_0771	5.384e-110	359.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,27Y2J@189775|Thermomicrobia	189775|Thermomicrobia	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
MMS3_k127_1588081_2	479434.Sthe_0250	5.522e-78	268.0	COG0726@1|root,COG0726@2|Bacteria,2G76U@200795|Chloroflexi	200795|Chloroflexi	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
MMS3_k127_1588081_3	479434.Sthe_1395	1.362e-18	88.0	COG0316@1|root,COG0316@2|Bacteria	2|Bacteria	S	protein maturation	nfuA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564	-	ko:K07400,ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn,NifU
MMS3_k127_1588081_0	479434.Sthe_3474	6.116e-180	572.0	COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi,27XRM@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
MMS3_k127_1588081_4	1227487.C474_07362	8.581e-06	51.0	COG1921@1|root,arCOG07389@2157|Archaea,2XU18@28890|Euryarchaeota,23SCH@183963|Halobacteria	183963|Halobacteria	E	COG1921 Selenocysteine synthase seryl-tRNASer selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
MMS3_k127_1592630_1	479434.Sthe_0096	2.076e-215	675.0	COG2234@1|root,COG2234@2|Bacteria,2G9MK@200795|Chloroflexi,27XKJ@189775|Thermomicrobia	189775|Thermomicrobia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_1592630_0	479434.Sthe_0259	0.0	1094.0	COG1529@1|root,COG1529@2|Bacteria,2G82V@200795|Chloroflexi,27XQT@189775|Thermomicrobia	189775|Thermomicrobia	C	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_1595933_7	219305.MCAG_00295	1.205e-26	117.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM,NLPC_P60,SH3_3
MMS3_k127_1595933_2	479434.Sthe_0449	3.455e-82	300.0	COG3858@1|root,COG3858@2|Bacteria,2G7HP@200795|Chloroflexi,27XZM@189775|Thermomicrobia	2|Bacteria	S	PFAM glycoside hydrolase, family 18	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Cu_amine_oxidN1,FAD_oxidored,Glyco_hydro_18,Hydrolase_2,Polysacc_deac_1,SLH
MMS3_k127_1595933_1	219305.MCAG_00296	4.306e-129	426.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
MMS3_k127_1595933_0	68170.KL590558_gene5388	3.757e-144	475.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_1595933_3	656024.FsymDg_4400	3.562e-69	263.0	COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,2I4BA@201174|Actinobacteria,4EXHK@85013|Frankiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
MMS3_k127_1595933_4	479434.Sthe_1437	2.342e-55	202.0	COG0745@1|root,COG0745@2|Bacteria,2G8ZD@200795|Chloroflexi,27Z5Y@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1595933_6	479434.Sthe_1437	6.782e-27	114.0	COG0745@1|root,COG0745@2|Bacteria,2G8ZD@200795|Chloroflexi,27Z5Y@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1607868_3	1217718.ALOU01000075_gene4457	2.048e-13	74.0	COG5470@1|root,COG5470@2|Bacteria,1QBR2@1224|Proteobacteria,2WAI5@28216|Betaproteobacteria,1KB5V@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
MMS3_k127_1607868_4	391615.ABSJ01000005_gene546	2.931e-09	65.0	COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,1S5RX@1236|Gammaproteobacteria,1JB6C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
MMS3_k127_1607868_2	1395587.P364_0118635	1.389e-36	147.0	2BZXU@1|root,32VRS@2|Bacteria,1VE6K@1239|Firmicutes,4IRFI@91061|Bacilli,276RQ@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function with HXXEE motif	-	-	-	-	-	-	-	-	-	-	-	-	HXXEE
MMS3_k127_1607868_5	1545702.LACWKB8_0419	3.729e-08	57.0	COG4047@1|root,COG4047@2|Bacteria,1U5P1@1239|Firmicutes,4IFDM@91061|Bacilli,3F697@33958|Lactobacillaceae	91061|Bacilli	L	oxidized base lesion DNA N-glycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1607868_0	479434.Sthe_3181	0.0	1092.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_1607868_1	1382356.JQMP01000003_gene1713	4.203e-65	239.0	COG2373@1|root,COG2373@2|Bacteria,2GBHR@200795|Chloroflexi,27YXZ@189775|Thermomicrobia	189775|Thermomicrobia	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1613139_1	479434.Sthe_2484	4.014e-142	457.0	COG1446@1|root,COG1446@2|Bacteria,2G6AS@200795|Chloroflexi,27XW0@189775|Thermomicrobia	189775|Thermomicrobia	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
MMS3_k127_1613139_5	323848.Nmul_A2484	3.052e-10	68.0	2BVVW@1|root,32175@2|Bacteria,1QZ0X@1224|Proteobacteria,2VSMJ@28216|Betaproteobacteria,374RH@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
MMS3_k127_1613139_3	926550.CLDAP_28300	4.528e-72	255.0	COG2267@1|root,COG2267@2|Bacteria,2G6KF@200795|Chloroflexi	200795|Chloroflexi	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
MMS3_k127_1613139_0	479434.Sthe_2487	1.561e-175	557.0	COG2421@1|root,COG2421@2|Bacteria,2G63Y@200795|Chloroflexi,27XIA@189775|Thermomicrobia	189775|Thermomicrobia	C	PFAM Acetamidase Formamidase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
MMS3_k127_1613139_2	479434.Sthe_2500	1.22e-104	345.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi,27XFS@189775|Thermomicrobia	189775|Thermomicrobia	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
MMS3_k127_1613139_4	479434.Sthe_2501	1.158e-38	151.0	COG3467@1|root,COG3467@2|Bacteria,2G77X@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
MMS3_k127_1613139_6	479434.Sthe_2526	1.2e-08	60.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
MMS3_k127_1619145_0	485913.Krac_7217	2.16e-39	150.0	COG4260@1|root,COG4260@2|Bacteria	2|Bacteria	N	virion core protein, lumpy skin disease virus	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4428,PrsW-protease
MMS3_k127_1619145_1	485913.Krac_7216	9.078e-26	118.0	2AGQY@1|root,2ZVHH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1619145_2	710421.Mycch_1126	9.651e-08	59.0	COG1846@1|root,COG1846@2|Bacteria,2IMA9@201174|Actinobacteria,239EF@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMS3_k127_1619145_3	479434.Sthe_2446	1.546e-06	54.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_1619145_4	886293.Sinac_2445	8.79e-05	45.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,M60-like_N,PSCyt1,PSCyt2,PSD1,Peptidase_M60
MMS3_k127_1640616_1	511.JT27_15025	4.104e-37	147.0	2EHU2@1|root,33BJQ@2|Bacteria,1NMC6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1640616_0	338969.Rfer_1047	1.158e-40	168.0	2DMCF@1|root,32JPI@2|Bacteria,1QVSN@1224|Proteobacteria,2VVT8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
MMS3_k127_1642748_7	983920.Y88_2329	9.95e-15	78.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,2K0Q2@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_1642748_1	479434.Sthe_2597	1.098e-112	375.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
MMS3_k127_1642748_6	1123229.AUBC01000047_gene3803	2.114e-56	204.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2U28G@28211|Alphaproteobacteria,3JVNQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Asp/Glu/Hydantoin racemase	MA20_32210	-	5.1.99.3	ko:K16841	ko00230,ko01120,map00230,map01120	-	R03925	RC01027	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
MMS3_k127_1642748_5	457570.Nther_2200	5.848e-102	344.0	COG4608@1|root,COG4608@2|Bacteria,1V1XB@1239|Firmicutes,24EQI@186801|Clostridia	186801|Clostridia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMS3_k127_1642748_3	1443111.JASG01000004_gene3183	3.101e-108	365.0	COG0444@1|root,COG0444@2|Bacteria,1MZF6@1224|Proteobacteria,2U13M@28211|Alphaproteobacteria,3ZWC9@60136|Sulfitobacter	28211|Alphaproteobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
MMS3_k127_1642748_2	1342299.Z947_1183	1.299e-108	360.0	COG1173@1|root,COG1173@2|Bacteria,1RBAG@1224|Proteobacteria,2U6R4@28211|Alphaproteobacteria,3ZWMU@60136|Sulfitobacter	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_1642748_4	1532558.JL39_17050	9.941e-107	355.0	COG0601@1|root,COG0601@2|Bacteria,1NH5E@1224|Proteobacteria,2U684@28211|Alphaproteobacteria,4BBG7@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_1642748_0	1532558.JL39_17055	2.772e-171	552.0	COG0747@1|root,COG0747@2|Bacteria,1R59W@1224|Proteobacteria,2U7T7@28211|Alphaproteobacteria,4BC9V@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_1652300_1	479434.Sthe_0632	4.865e-96	323.0	COG0122@1|root,COG0122@2|Bacteria,2G8TI@200795|Chloroflexi,27YWG@189775|Thermomicrobia	189775|Thermomicrobia	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_1652300_0	479434.Sthe_0627	6.936e-173	554.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi,27XMU@189775|Thermomicrobia	189775|Thermomicrobia	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
MMS3_k127_1653166_0	1382356.JQMP01000003_gene1536	3.927e-128	415.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi,27XP6@189775|Thermomicrobia	189775|Thermomicrobia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
MMS3_k127_1653166_1	1382356.JQMP01000003_gene1537	4.442e-29	122.0	COG1846@1|root,COG1846@2|Bacteria,2G7D6@200795|Chloroflexi,27Z9E@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMS3_k127_1663316_5	479434.Sthe_0227	5.473e-22	96.0	COG0587@1|root,COG0587@2|Bacteria,2G811@200795|Chloroflexi,27Z3J@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
MMS3_k127_1663316_3	479434.Sthe_0226	2.044e-53	194.0	COG3153@1|root,COG3153@2|Bacteria,2G7B4@200795|Chloroflexi	200795|Chloroflexi	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
MMS3_k127_1663316_1	479434.Sthe_2211	7.307e-132	425.0	COG0491@1|root,COG0491@2|Bacteria,2G846@200795|Chloroflexi,27YRW@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1663316_4	383372.Rcas_0029	1.254e-32	145.0	COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,377RQ@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_1663316_2	562970.Btus_1743	9.962e-110	362.0	COG1715@1|root,COG1715@2|Bacteria,1V1TA@1239|Firmicutes,4HC3T@91061|Bacilli,27AHR@186823|Alicyclobacillaceae	91061|Bacilli	L	Restriction endonuclease	mrr2	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	MerR_1,Mrr_N,Mrr_cat
MMS3_k127_1663316_0	479434.Sthe_1860	1.909e-257	815.0	COG4745@1|root,COG4745@2|Bacteria,2G6HI@200795|Chloroflexi,27XK8@189775|Thermomicrobia	189775|Thermomicrobia	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_1665931_0	479434.Sthe_0485	5.828e-132	449.0	COG0457@1|root,COG1396@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
MMS3_k127_1665931_2	479434.Sthe_0024	3.409e-18	90.0	2DCSV@1|root,2ZF7N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1674671_4	485913.Krac_4602	5.641e-78	279.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_1674671_1	479434.Sthe_1393	1.647e-95	317.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi,27Y58@189775|Thermomicrobia	189775|Thermomicrobia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_1674671_7	324057.Pjdr2_1637	4.616e-40	155.0	COG0454@1|root,COG0510@1|root,COG0456@2|Bacteria,COG0510@2|Bacteria,1UY77@1239|Firmicutes,4HCZH@91061|Bacilli,26STS@186822|Paenibacillaceae	91061|Bacilli	M	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_1674671_3	479434.Sthe_2145	6.45e-86	300.0	COG2211@1|root,COG2211@2|Bacteria,2G7ZY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1674671_0	485913.Krac_12610	3.095e-187	609.0	COG1506@1|root,COG1506@2|Bacteria,2G7MH@200795|Chloroflexi	200795|Chloroflexi	EU	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_1674671_6	266835.14026239	2.114e-43	163.0	COG0662@1|root,COG0662@2|Bacteria,1N56T@1224|Proteobacteria,2UCUS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_1674671_8	644076.SCH4B_3643	9.872e-16	80.0	COG2128@1|root,COG2128@2|Bacteria,1PQ1G@1224|Proteobacteria,2U17A@28211|Alphaproteobacteria,4NBJF@97050|Ruegeria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_1674671_9	1033810.HLPCO_002949	4.717e-15	78.0	COG2128@1|root,COG2128@2|Bacteria,2NS09@2323|unclassified Bacteria	2|Bacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_1674671_5	436229.JOEH01000046_gene7378	1.274e-49	190.0	COG2355@1|root,COG2355@2|Bacteria,2GN82@201174|Actinobacteria,2NGDY@228398|Streptacidiphilus	201174|Actinobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMS3_k127_1674671_2	479434.Sthe_0854	5.408e-86	300.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Z0M@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_1675730_10	309801.trd_A0566	2.716e-16	81.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi,27Z3G@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMS3_k127_1675730_5	479434.Sthe_2777	3.172e-87	291.0	COG2080@1|root,COG2080@2|Bacteria,2GBCT@200795|Chloroflexi,27YT4@189775|Thermomicrobia	189775|Thermomicrobia	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2_2
MMS3_k127_1675730_0	479434.Sthe_2776	0.0	1378.0	COG1529@1|root,COG1529@2|Bacteria,2G7QH@200795|Chloroflexi,27YUU@189775|Thermomicrobia	189775|Thermomicrobia	C	Carbon-monoxide dehydrogenase, large subunit	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_1675730_2	479434.Sthe_2775	1.357e-129	421.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2G88Z@200795|Chloroflexi,27YSQ@189775|Thermomicrobia	189775|Thermomicrobia	O	metallochaperone-like domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
MMS3_k127_1675730_4	1122927.KB895420_gene4217	1.162e-104	352.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,26SE2@186822|Paenibacillaceae	91061|Bacilli	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
MMS3_k127_1675730_7	479434.Sthe_3290	5.274e-52	189.0	COG3663@1|root,COG3663@2|Bacteria,2G9BC@200795|Chloroflexi	200795|Chloroflexi	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_1675730_3	439235.Dalk_4098	3.231e-109	367.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,43BFP@68525|delta/epsilon subdivisions,2X6U3@28221|Deltaproteobacteria,2MPIH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_1675730_8	323259.Mhun_0903	4.135e-24	113.0	COG0483@1|root,arCOG01349@2157|Archaea,2XUBB@28890|Euryarchaeota,2N9NZ@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
MMS3_k127_1675730_1	479434.Sthe_2772	0.0	1356.0	COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,27XND@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMS3_k127_1675730_14	1032480.MLP_05090	5.458e-05	49.0	COG1249@1|root,COG1249@2|Bacteria,2I5DW@201174|Actinobacteria	201174|Actinobacteria	C	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
MMS3_k127_1675730_12	446466.Cfla_0426	5.509e-06	50.0	COG1249@1|root,COG1249@2|Bacteria,2I5DW@201174|Actinobacteria	201174|Actinobacteria	C	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
MMS3_k127_1675730_6	479434.Sthe_2771	2.239e-55	198.0	COG0350@1|root,COG0350@2|Bacteria,2G98B@200795|Chloroflexi,27Z9T@189775|Thermomicrobia	189775|Thermomicrobia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
MMS3_k127_1675730_9	33876.JNXY01000021_gene4740	7.096e-17	86.0	COG0346@1|root,COG0346@2|Bacteria,2II0X@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_1675730_11	479434.Sthe_2769	1.162e-13	72.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia	189775|Thermomicrobia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_1683607_3	349521.HCH_05597	1.797e-38	146.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1S82G@1236|Gammaproteobacteria,1XKS3@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMS3_k127_1683607_0	485913.Krac_1887	1.933e-175	558.0	COG1680@1|root,COG1680@2|Bacteria,2G6IE@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_1683607_2	1097668.BYI23_B012200	1.817e-42	158.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VSH3@28216|Betaproteobacteria,1K72M@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM DGPFAETKE family protein	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMS3_k127_1683607_1	235985.BBPN01000033_gene5	1.62e-71	246.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,2NJUF@228398|Streptacidiphilus	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMS3_k127_1683607_4	1121335.Clst_1497	7.715e-14	75.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,3WHYU@541000|Ruminococcaceae	186801|Clostridia	K	PFAM response regulator receiver	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_1688646_1	620914.JH621272_gene1870	8.761e-63	217.0	COG1082@1|root,COG1082@2|Bacteria,4NHMP@976|Bacteroidetes,1IFBH@117743|Flavobacteriia,2YKC5@290174|Aquimarina	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
MMS3_k127_1688646_0	713587.THITH_03310	0.0	1184.0	COG1452@1|root,COG1452@2|Bacteria,1QW3G@1224|Proteobacteria,1T2RD@1236|Gammaproteobacteria,1WWPC@135613|Chromatiales	135613|Chromatiales	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1711698_11	479434.Sthe_1939	1.313e-17	89.0	COG0491@1|root,COG0491@2|Bacteria,2G8W8@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_1711698_10	368407.Memar_2300	3.923e-20	98.0	COG0613@1|root,arCOG00302@2157|Archaea,2XSWE@28890|Euryarchaeota,2N9Q2@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
MMS3_k127_1711698_3	1123023.JIAI01000003_gene2762	3.046e-78	277.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_1711698_5	196367.JNFG01000009_gene6362	2.608e-65	235.0	COG1024@1|root,COG1024@2|Bacteria,1MVB1@1224|Proteobacteria,2VIZ5@28216|Betaproteobacteria,1K2IT@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.1.2.41,4.2.1.101	ko:K18383	ko00360,ko01100,ko01110,map00360,map01100,map01110	-	R05772,R05773	RC00307,RC01468,RC01828	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS3_k127_1711698_7	1089551.KE386572_gene2294	4.854e-47	184.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,4BPJW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
MMS3_k127_1711698_8	1123023.JIAI01000003_gene2764	3.75e-34	136.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_1711698_0	1123023.JIAI01000003_gene2765	1.057e-122	404.0	COG0183@1|root,COG0183@2|Bacteria,2H3G7@201174|Actinobacteria,4E97C@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1711698_9	595537.Varpa_2480	7.77e-23	108.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,2VNHN@28216|Betaproteobacteria,4AJ67@80864|Comamonadaceae	28216|Betaproteobacteria	K	UTRA	-	-	-	ko:K03486,ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
MMS3_k127_1711698_1	1380394.JADL01000001_gene2482	3.222e-91	316.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMS3_k127_1711698_4	391735.Veis_4965	1.592e-72	257.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2W02P@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_1711698_2	1297865.APJD01000009_gene2849	1.661e-90	308.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR0N@28211|Alphaproteobacteria,3JUIB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_1718138_0	543728.Vapar_4526	1.048e-60	221.0	COG3843@1|root,COG3843@2|Bacteria,1MVHF@1224|Proteobacteria,2VS34@28216|Betaproteobacteria,4AIHZ@80864|Comamonadaceae	28216|Betaproteobacteria	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
MMS3_k127_172933_4	1382356.JQMP01000004_gene503	2.266e-67	232.0	COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia	189775|Thermomicrobia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_172933_6	485913.Krac_12156	6.173e-33	133.0	COG1162@1|root,COG1162@2|Bacteria	2|Bacteria	S	GTPase activity	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RNHCP,RsgA_GTPase
MMS3_k127_172933_3	1121945.ATXS01000007_gene462	1.008e-82	286.0	COG1171@1|root,arCOG01431@2157|Archaea,2XT4W@28890|Euryarchaeota,23SNZ@183963|Halobacteria	183963|Halobacteria	E	Threonine dehydratase	ilvA1	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
MMS3_k127_172933_5	1382356.JQMP01000003_gene1897	7.911e-64	223.0	COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
MMS3_k127_172933_0	309801.trd_0513	6.589e-130	431.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi	200795|Chloroflexi	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
MMS3_k127_172933_2	771875.Ferpe_0384	2.625e-85	294.0	COG1087@1|root,COG1087@2|Bacteria,2GC80@200918|Thermotogae	200918|Thermotogae	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS3_k127_172933_1	479434.Sthe_1508	1.362e-95	323.0	COG1485@1|root,COG1485@2|Bacteria	2|Bacteria	S	mitochondrial protein catabolic process	-	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
MMS3_k127_1737253_1	1382356.JQMP01000003_gene1829	6.318e-95	327.0	COG1840@1|root,COG1840@2|Bacteria,2GBNE@200795|Chloroflexi,27ZCW@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1737253_7	1094715.CM001373_gene1935	1.237e-10	74.0	COG5661@1|root,COG5661@2|Bacteria,1NJW0@1224|Proteobacteria,1TBMM@1236|Gammaproteobacteria,1JG4Z@118969|Legionellales	118969|Legionellales	O	Bacterial protein of unknown function (DUF922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
MMS3_k127_1737253_3	1380347.JNII01000007_gene292	1.582e-63	233.0	COG1277@1|root,COG1277@2|Bacteria,2GM0N@201174|Actinobacteria,4EVKG@85013|Frankiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_1737253_2	1380347.JNII01000007_gene292	5.869e-68	244.0	COG1277@1|root,COG1277@2|Bacteria,2GM0N@201174|Actinobacteria,4EVKG@85013|Frankiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_1737253_0	408672.NBCG_00176	1.982e-127	413.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4DPKX@85009|Propionibacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1737253_4	1394178.AWOO02000034_gene8333	6.908e-58	203.0	COG1725@1|root,COG1725@2|Bacteria,2IHTD@201174|Actinobacteria,4EIYZ@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
MMS3_k127_1737253_8	521393.JH806634_gene2268	8.194e-10	63.0	COG4194@1|root,COG4194@2|Bacteria,2HUI7@201174|Actinobacteria,4D7WF@85005|Actinomycetales	201174|Actinobacteria	K	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1737253_5	479434.Sthe_2980	3.846e-49	183.0	COG3881@1|root,COG3881@2|Bacteria,2GBNJ@200795|Chloroflexi,27YD3@189775|Thermomicrobia	189775|Thermomicrobia	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
MMS3_k127_1737253_6	1157632.AQWQ01000005_gene879	5.761e-48	180.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria	201174|Actinobacteria	I	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
MMS3_k127_1743505_1	525904.Tter_2834	1.967e-80	282.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	ytcB	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
MMS3_k127_1743505_0	743299.Acife_0999	1.366e-86	301.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,1S4W5@1236|Gammaproteobacteria,2NDNC@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
MMS3_k127_1743505_2	743299.Acife_1000	2.053e-73	265.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,2NDHR@225057|Acidithiobacillales	225057|Acidithiobacillales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_1743505_3	1407650.BAUB01000005_gene1295	1.924e-68	248.0	COG0438@1|root,COG0438@2|Bacteria,1G271@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	icsA	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_1743505_4	349163.Acry_0207	2.776e-14	77.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2JVUJ@204441|Rhodospirillales	204441|Rhodospirillales	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_1743969_1	586413.CCDL010000001_gene1218	5.647e-87	301.0	COG1680@1|root,COG1680@2|Bacteria,1V3KP@1239|Firmicutes,4IDK5@91061|Bacilli,23KW4@182709|Oceanobacillus	91061|Bacilli	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_1743969_0	309801.trd_0281	8.073e-198	624.0	COG0624@1|root,COG0624@2|Bacteria,2GB9S@200795|Chloroflexi,27YDU@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_1743969_2	479434.Sthe_2420	3.459e-82	282.0	COG0546@1|root,COG0546@2|Bacteria,2G9CI@200795|Chloroflexi,27YAX@189775|Thermomicrobia	189775|Thermomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
MMS3_k127_1743969_4	1121372.AULK01000008_gene597	2.403e-47	173.0	COG0640@1|root,COG0640@2|Bacteria,2HWSZ@201174|Actinobacteria,4FSX8@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1743969_3	543632.JOJL01000027_gene2799	2.496e-57	203.0	COG3832@1|root,COG3832@2|Bacteria,2INYI@201174|Actinobacteria,4DJBG@85008|Micromonosporales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMS3_k127_1748090_3	935548.KI912159_gene3707	6.317e-11	70.0	2EMUN@1|root,30Z1W@2|Bacteria,1PA8R@1224|Proteobacteria,2UZJK@28211|Alphaproteobacteria,43Q2Q@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1748090_1	1128421.JAGA01000002_gene256	2.333e-87	311.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	hhoA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_1748090_0	224911.27352666	3.235e-148	474.0	COG2267@1|root,COG2267@2|Bacteria,1QU3E@1224|Proteobacteria,2TVXS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the peptidase S33 family	pipch2	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
MMS3_k127_1748090_2	518766.Rmar_1581	4.179e-41	156.0	COG0076@1|root,COG0076@2|Bacteria,4NGRW@976|Bacteroidetes,1FJ4Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
MMS3_k127_1755411_5	1278073.MYSTI_05644	0.0007086	50.0	COG0643@1|root,COG0784@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,1MUAG@1224|Proteobacteria,439YY@68525|delta/epsilon subdivisions,2X1I2@28221|Deltaproteobacteria,2YW92@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	cheA3	-	2.7.13.3	ko:K03407,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
MMS3_k127_1755411_1	1463909.KL585952_gene4308	3.881e-51	187.0	COG0640@1|root,COG0640@2|Bacteria,2GQ1F@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_1755411_4	1283287.KB822576_gene3802	2.377e-14	80.0	2DSZE@1|root,33I16@2|Bacteria,2IMV6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1453
MMS3_k127_1755411_2	1408422.JHYF01000006_gene1241	3.23e-25	115.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,36IAW@31979|Clostridiaceae	186801|Clostridia	K	GntR family	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS3_k127_1755411_0	1463917.JODC01000007_gene7294	1.354e-72	252.0	COG1011@1|root,COG1011@2|Bacteria,2IBB1@201174|Actinobacteria	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMS3_k127_1755411_3	749414.SBI_00474	2.782e-17	83.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_1763717_2	928724.SacglDRAFT_02023	2.645e-23	100.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
MMS3_k127_1763717_0	644966.Tmar_0712	8.986e-113	382.0	COG0165@1|root,COG0165@2|Bacteria,1U4V0@1239|Firmicutes,24EEH@186801|Clostridia	186801|Clostridia	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
MMS3_k127_1763717_1	113395.AXAI01000002_gene5233	1.651e-101	340.0	COG2141@1|root,COG2141@2|Bacteria,1N4HT@1224|Proteobacteria,2UEZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_1765935_0	247639.MGP2080_02126	1.585e-117	388.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1S0H1@1236|Gammaproteobacteria,1JBTT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Zn-dependent alcohol dehydrogenases	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1765935_1	309801.trd_A0629	2.028e-104	341.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
MMS3_k127_1767208_0	479434.Sthe_3244	7.457e-167	542.0	COG2133@1|root,COG2133@2|Bacteria,2GBHS@200795|Chloroflexi,27XSU@189775|Thermomicrobia	189775|Thermomicrobia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1767208_5	1198114.AciX9_1799	6.239e-51	189.0	COG0500@1|root,COG2226@2|Bacteria,3Y65B@57723|Acidobacteria,2JKYP@204432|Acidobacteriia	204432|Acidobacteriia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
MMS3_k127_1767208_4	926566.Terro_1691	4.483e-58	220.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMS3_k127_1767208_1	401053.AciPR4_3734	1.747e-159	515.0	COG0451@1|root,COG0451@2|Bacteria,3Y3CF@57723|Acidobacteria,2JI4M@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis protein	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
MMS3_k127_1767208_2	479434.Sthe_2181	1.757e-94	329.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi,27XUT@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
MMS3_k127_1767208_6	485913.Krac_7974	1.478e-26	122.0	COG3222@1|root,COG3222@2|Bacteria,2G988@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
MMS3_k127_1767208_3	671143.DAMO_0614	1.713e-58	213.0	COG1215@1|root,COG1215@2|Bacteria,2NRME@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_1775404_3	479434.Sthe_1833	4.036e-155	501.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi,27YZS@189775|Thermomicrobia	189775|Thermomicrobia	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1775404_2	479434.Sthe_0405	1.168e-165	550.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,27Y5Y@189775|Thermomicrobia	189775|Thermomicrobia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD
MMS3_k127_1775404_0	479434.Sthe_0405	3.133e-227	743.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,27Y5Y@189775|Thermomicrobia	189775|Thermomicrobia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD
MMS3_k127_1775404_4	479434.Sthe_0406	2.171e-141	456.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi,27Y2K@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_1775404_8	316274.Haur_0626	1.946e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,2G8XR@200795|Chloroflexi,377W5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_1775404_7	309801.trd_0224	2.922e-67	237.0	COG1136@1|root,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,27Y7U@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1775404_5	1121422.AUMW01000002_gene2292	3.264e-87	317.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,260CG@186807|Peptococcaceae	186801|Clostridia	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_1775404_1	479434.Sthe_0407	3.142e-218	689.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2G6D3@200795|Chloroflexi,27XQM@189775|Thermomicrobia	189775|Thermomicrobia	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
MMS3_k127_1775404_6	479434.Sthe_0127	1.075e-74	260.0	COG0526@1|root,COG0526@2|Bacteria,2G8YT@200795|Chloroflexi,27YFH@189775|Thermomicrobia	200795|Chloroflexi	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
MMS3_k127_1784580_1	1247726.MIM_c20810	2.097e-61	218.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
MMS3_k127_1784580_0	631454.N177_3030	1.426e-207	657.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2TW3X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,Sigma54_activat
MMS3_k127_1785235_1	937777.Deipe_1810	9.094e-53	190.0	COG0435@1|root,COG0435@2|Bacteria	2|Bacteria	O	Glutathione S-transferase	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7,2.5.1.18	ko:K00799,ko:K07393	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	iECW_1372.ECW_m3373,iWFL_1372.ECW_m3373	GST_C_2,GST_N_2
MMS3_k127_1785235_0	1366050.N234_28030	3.77e-146	473.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2VM1E@28216|Betaproteobacteria,1KGMC@119060|Burkholderiaceae	1224|Proteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1785235_4	1382356.JQMP01000004_gene502	3.44e-16	94.0	2A4UQ@1|root,30TG9@2|Bacteria,2GA4B@200795|Chloroflexi,27Z74@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1785235_2	383372.Rcas_1915	1.52e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,2GB53@200795|Chloroflexi,377AG@32061|Chloroflexia	32061|Chloroflexia	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_1785235_3	760568.Desku_0782	1.875e-45	171.0	COG4974@1|root,COG4974@2|Bacteria,1V2D0@1239|Firmicutes,25MA5@186801|Clostridia,265CQ@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
MMS3_k127_1787593_10	479434.Sthe_0375	2.454e-72	248.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,27XUY@189775|Thermomicrobia	189775|Thermomicrobia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_1787593_6	479434.Sthe_0374	1.414e-115	380.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,27XQH@189775|Thermomicrobia	189775|Thermomicrobia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
MMS3_k127_1787593_0	1382356.JQMP01000003_gene1315	1.898e-145	467.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi,27XWK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
MMS3_k127_1787593_13	479434.Sthe_0372	4.205e-30	119.0	COG0333@1|root,COG0333@2|Bacteria,2G7EA@200795|Chloroflexi,27YMM@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
MMS3_k127_1787593_12	479434.Sthe_0371	2.004e-49	182.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi,27YCW@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
MMS3_k127_1787593_4	479434.Sthe_3330	3.266e-130	424.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi,27Y0M@189775|Thermomicrobia	189775|Thermomicrobia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
MMS3_k127_1787593_8	479434.Sthe_0369	3.187e-95	317.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,27XMW@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1787593_2	479434.Sthe_0368	1.462e-134	449.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi,27XFQ@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
MMS3_k127_1787593_11	1303518.CCALI_01602	6.103e-61	219.0	COG0745@1|root,COG0745@2|Bacteria	1303518.CCALI_01602|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1787593_3	479434.Sthe_0367	3.163e-130	428.0	COG0226@1|root,COG0226@2|Bacteria,2GAAI@200795|Chloroflexi,27YVN@189775|Thermomicrobia	189775|Thermomicrobia	P	Phosphate ABC transporter, periplasmic phosphate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMS3_k127_1787593_1	479434.Sthe_0366	1.384e-134	435.0	COG0573@1|root,COG0573@2|Bacteria,2G6CV@200795|Chloroflexi,27YPC@189775|Thermomicrobia	189775|Thermomicrobia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS3_k127_1787593_7	479434.Sthe_0365	2.792e-112	370.0	COG0581@1|root,COG0581@2|Bacteria,2GBVI@200795|Chloroflexi,27YID@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMS3_k127_1787593_5	479434.Sthe_0364	4.481e-117	383.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi,27YZP@189775|Thermomicrobia	189775|Thermomicrobia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMS3_k127_1787593_9	404589.Anae109_0421	1.09e-93	317.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2YUBB@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMS3_k127_1794634_11	1476583.DEIPH_ctg050orf0040	4.604e-28	115.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC,TusA
MMS3_k127_1794634_5	1267533.KB906733_gene2816	4.164e-97	324.0	COG0596@1|root,COG0596@2|Bacteria,3Y5Q2@57723|Acidobacteria	57723|Acidobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_1794634_3	485913.Krac_2947	1.523e-111	366.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMS3_k127_1794634_2	485913.Krac_1531	3.228e-115	381.0	2C57D@1|root,2Z7RS@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
MMS3_k127_1794634_7	1122927.KB895431_gene95	4.913e-78	273.0	COG2723@1|root,COG2723@2|Bacteria,1VR3K@1239|Firmicutes,4HTQ5@91061|Bacilli,26ZTZ@186822|Paenibacillaceae	91061|Bacilli	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1794634_14	1432055.GLUCORHAEAF1_11365	3.989e-09	67.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,2U4VF@28211|Alphaproteobacteria,2JRM3@204441|Rhodospirillales	204441|Rhodospirillales	G	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
MMS3_k127_1794634_10	1121378.KB899743_gene3665	1.792e-30	124.0	COG1028@1|root,COG1028@2|Bacteria	1121378.KB899743_gene3665|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1794634_13	693661.Arcve_1429	6.189e-19	99.0	arCOG14052@1|root,arCOG14052@2157|Archaea,2Y2YJ@28890|Euryarchaeota,246SX@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1794634_12	693661.Arcve_1430	4.57e-25	121.0	COG1470@1|root,COG1572@1|root,arCOG02081@2157|Archaea,arCOG02532@2157|Archaea	2157|Archaea	P	APHP domain protein	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	A2M_comp,Big_3_5,CARDB,CarboxypepD_reg,DUF3344,Inhibitor_I9,PKD,Peptidase_S8,Thiol-ester_cl
MMS3_k127_1794634_6	1121377.KB906398_gene2693	7.948e-82	280.0	COG1028@1|root,COG1028@2|Bacteria,1WM8P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1794634_0	1146883.BLASA_1778	1.41e-178	573.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,4EVYU@85013|Frankiales	201174|Actinobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
MMS3_k127_1794634_8	1146883.BLASA_1779	2.264e-60	223.0	COG1413@1|root,COG1413@2|Bacteria,2IHYB@201174|Actinobacteria	201174|Actinobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
MMS3_k127_1794634_1	1146883.BLASA_1780	1.404e-147	492.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3,2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K07676,ko:K10715,ko:K20976	ko00230,ko02020,ko02024,ko02025,ko02026,ko04112,ko04113,ko04213,map00230,map02020,map02024,map02025,map02026,map04112,map04113,map04213	M00474,M00511,M00517,M00695,M00820	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg,Trans_reg_C
MMS3_k127_1794634_9	1173028.ANKO01000208_gene5102	2.191e-45	167.0	COG0745@1|root,COG0745@2|Bacteria,1G5ZH@1117|Cyanobacteria,1HHCH@1150|Oscillatoriales	1117|Cyanobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMS3_k127_1794634_4	251221.35214786	3.254e-109	363.0	COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_9,PHY
MMS3_k127_1794754_7	479434.Sthe_0713	6.647e-33	131.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi,27YHZ@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1794754_0	479434.Sthe_0712	2.249e-165	538.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi,27YA2@189775|Thermomicrobia	189775|Thermomicrobia	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1794754_6	479434.Sthe_0711	1.65e-43	171.0	2A4SK@1|root,30TE0@2|Bacteria,2GBCB@200795|Chloroflexi,27YRE@189775|Thermomicrobia	189775|Thermomicrobia	S	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
MMS3_k127_1794754_3	479434.Sthe_0709	3.688e-64	223.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,27YAD@189775|Thermomicrobia	189775|Thermomicrobia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
MMS3_k127_1794754_4	479434.Sthe_0708	3.361e-63	221.0	COG0245@1|root,COG0245@2|Bacteria,2G6RA@200795|Chloroflexi,27YBC@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
MMS3_k127_1794754_5	479434.Sthe_0707	1.495e-61	219.0	COG1211@1|root,COG1211@2|Bacteria,2G6UP@200795|Chloroflexi,27Y9J@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
MMS3_k127_1794754_2	525904.Tter_1561	1.256e-73	261.0	COG4956@1|root,COG4956@2|Bacteria,2NP0D@2323|unclassified Bacteria	2|Bacteria	S	Large family of predicted nucleotide-binding domains	yacL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
MMS3_k127_1794754_1	479434.Sthe_0705	1.605e-99	332.0	COG0613@1|root,COG0613@2|Bacteria,2G6H4@200795|Chloroflexi,27YVQ@189775|Thermomicrobia	189775|Thermomicrobia	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
MMS3_k127_1798501_0	926550.CLDAP_14410	4.061e-67	248.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1798501_1	1445613.JALM01000034_gene5234	1.751e-60	218.0	COG0745@1|root,COG0745@2|Bacteria,2GMP1@201174|Actinobacteria,4E243@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1804015_0	1313172.YM304_13510	1.656e-66	236.0	COG0596@1|root,COG0596@2|Bacteria,2IA2Y@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
MMS3_k127_1804015_2	105422.BBPM01000005_gene6165	2.765e-14	75.0	2EJ7M@1|root,33CYT@2|Bacteria,2GWJB@201174|Actinobacteria,2NK09@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1804015_1	1356854.N007_20095	6.824e-17	92.0	2DMH3@1|root,32RGP@2|Bacteria,1VN64@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1808970_2	1101191.KI912577_gene2934	2.202e-17	93.0	29XEM@1|root,30J4T@2|Bacteria,1PJRP@1224|Proteobacteria,2V18D@28211|Alphaproteobacteria,1JWTV@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1808970_0	754035.Mesau_06011	4.243e-156	519.0	COG2801@1|root,COG2801@2|Bacteria,1MXCK@1224|Proteobacteria,2TTWU@28211|Alphaproteobacteria,43M1V@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Mu transposase, C-terminal	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_Mu_2,Mu-transpos_C,rve
MMS3_k127_1808970_1	1096546.WYO_0103	5.554e-72	256.0	COG2842@1|root,COG2842@2|Bacteria,1RCQQ@1224|Proteobacteria,2U43M@28211|Alphaproteobacteria,1JWWS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Bacterial TniB protein	-	-	-	-	-	-	-	-	-	-	-	-	TniB
MMS3_k127_1808970_3	754035.Mesau_06013	1.054e-10	70.0	29W51@1|root,30HPZ@2|Bacteria,1P242@1224|Proteobacteria,2UUHD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	TniQ
MMS3_k127_1822369_3	485913.Krac_1357	7.366e-59	209.0	COG2008@1|root,COG2008@2|Bacteria	2|Bacteria	E	L-allo-threonine aldolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
MMS3_k127_1822369_6	479434.Sthe_1130	6.381e-17	86.0	COG2318@1|root,COG2318@2|Bacteria,2G77R@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_1822369_9	479434.Sthe_1130	1.144e-08	58.0	COG2318@1|root,COG2318@2|Bacteria,2G77R@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_1822369_2	479433.Caci_5534	2.956e-75	267.0	COG1073@1|root,COG1073@2|Bacteria,2GKYQ@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4
MMS3_k127_1822369_5	656024.FsymDg_3049	5.742e-23	103.0	COG5485@1|root,COG5485@2|Bacteria,2INPT@201174|Actinobacteria,4ETGU@85013|Frankiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
MMS3_k127_1822369_4	266117.Rxyl_0525	4.77e-33	136.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4CQDC@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_1822369_11	1122239.AULS01000016_gene583	1.576e-06	51.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4FMB3@85023|Microbacteriaceae	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_1822369_0	298653.Franean1_7134	1.678e-154	499.0	COG4251@1|root,COG4251@2|Bacteria,2I2KA@201174|Actinobacteria,4ETVK@85013|Frankiales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K18351	ko01502,ko02020,map01502,map02020	M00651,M00658	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1822369_1	247156.NFA_6930	7.296e-124	399.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4FYFY@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18352	ko01502,ko02020,map01502,map02020	M00651,M00658	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1822369_7	479435.Kfla_3626	6.576e-17	89.0	COG1876@1|root,COG1876@2|Bacteria,2IHUG@201174|Actinobacteria,4DQIH@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
MMS3_k127_1822369_8	1445613.JALM01000027_gene6397	2.205e-09	62.0	COG1876@1|root,COG1876@2|Bacteria,2IHUG@201174|Actinobacteria,4E57N@85010|Pseudonocardiales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
MMS3_k127_1822369_10	1298863.AUEP01000013_gene4041	6.561e-07	56.0	2EBG5@1|root,335GQ@2|Bacteria,2GRUT@201174|Actinobacteria,4DSMC@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1829241_4	694430.Natoc_3239	2.054e-60	223.0	COG0006@1|root,arCOG01000@2157|Archaea,2XTI9@28890|Euryarchaeota,23TKY@183963|Halobacteria	183963|Halobacteria	E	Belongs to the peptidase M24B family	pepQ1	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_1829241_6	1144342.PMI40_03065	1.248e-33	139.0	COG1802@1|root,COG1802@2|Bacteria,1NWSI@1224|Proteobacteria,2VMNY@28216|Betaproteobacteria	28216|Betaproteobacteria	K	GntR family transcriptional regulator	-	-	-	ko:K11475	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
MMS3_k127_1829241_0	371042.NG99_19900	1.494e-101	344.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria	1224|Proteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_1829241_2	335543.Sfum_2375	2.006e-76	274.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,42NNZ@68525|delta/epsilon subdivisions,2WJ7C@28221|Deltaproteobacteria,2MRYC@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_1829241_1	1038862.KB893884_gene489	1.184e-82	282.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TT4C@28211|Alphaproteobacteria,3K3X4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_1829241_5	710421.Mycch_5294	9.434e-40	158.0	COG0726@1|root,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria,2335D@1762|Mycobacteriaceae	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_1829241_3	479434.Sthe_3009	2.191e-73	253.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,2G5QF@200795|Chloroflexi	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
MMS3_k127_1840970_1	479434.Sthe_2976	1.191e-101	334.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi,27XH6@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09820	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
MMS3_k127_1840970_0	479434.Sthe_2975	2.226e-126	411.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,27XKB@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC 3 transport family	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
MMS3_k127_1840970_3	383372.Rcas_2854	2.039e-60	224.0	COG0454@1|root,COG0456@2|Bacteria,2G92V@200795|Chloroflexi,377JP@32061|Chloroflexia	32061|Chloroflexia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_1840970_2	1343740.M271_20590	6.029e-81	282.0	COG3315@1|root,COG3315@2|Bacteria,2GP52@201174|Actinobacteria	201174|Actinobacteria	Q	O-Methyltransferase involved in polyketide biosynthesis	omt	-	-	-	-	-	-	-	-	-	-	-	LCM
MMS3_k127_1840970_4	946362.XP_004996892.1	1.137e-37	145.0	28N08@1|root,2QUJ0@2759|Eukaryota	2759|Eukaryota	-	-	MUC4	GO:0001894,GO:0002218,GO:0002220,GO:0002223,GO:0002253,GO:0002376,GO:0002429,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003008,GO:0003674,GO:0005102,GO:0005176,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007586,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010669,GO:0012505,GO:0016020,GO:0016021,GO:0016266,GO:0019538,GO:0022600,GO:0023052,GO:0030197,GO:0030277,GO:0031012,GO:0031224,GO:0031226,GO:0031347,GO:0031349,GO:0031974,GO:0032501,GO:0034645,GO:0036211,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0048871,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0071704,GO:0071944,GO:0080134,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K22017	-	-	-	-	ko00000,ko04131	-	-	-	NIDO,VWD
MMS3_k127_1852549_0	479434.Sthe_3300	2.861e-193	611.0	COG0665@1|root,COG0665@2|Bacteria,2G86Q@200795|Chloroflexi,27Y37@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_1852549_4	457429.ABJI02000385_gene4489	2.984e-05	52.0	2EEUI@1|root,30DVN@2|Bacteria,2GWIW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1852549_2	1298863.AUEP01000006_gene3325	4.561e-71	250.0	COG0702@1|root,COG0702@2|Bacteria,2HM0I@201174|Actinobacteria,4DSP9@85009|Propionibacteriales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
MMS3_k127_1852549_3	1385519.N801_15870	5.888e-38	147.0	COG3631@1|root,COG3631@2|Bacteria,2IP61@201174|Actinobacteria,4FHU1@85021|Intrasporangiaceae	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2,SnoaL_2
MMS3_k127_1852549_1	1206731.BAGB01000049_gene4889	1.727e-92	327.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	2.7.11.1	ko:K08282,ko:K13419	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12,TPR_7
MMS3_k127_1856889_2	63737.Npun_R0578	7.656e-22	96.0	COG1028@1|root,COG1028@2|Bacteria,1G2ZD@1117|Cyanobacteria,1HMVA@1161|Nostocales	1117|Cyanobacteria	IQ	PFAM short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1856889_1	1123258.AQXZ01000011_gene1517	5.863e-26	112.0	COG4319@1|root,COG4319@2|Bacteria,2H5WD@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
MMS3_k127_1856889_3	556261.HMPREF0240_03540	9.668e-06	57.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,24FGF@186801|Clostridia,36VMP@31979|Clostridiaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1856889_0	221288.JH992901_gene2456	9.098e-73	259.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria,1JIE9@1189|Stigonemataceae	1117|Cyanobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
MMS3_k127_1860733_10	479434.Sthe_1862	1.839e-27	115.0	COG0745@1|root,COG0745@2|Bacteria,2G9E3@200795|Chloroflexi	200795|Chloroflexi	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMS3_k127_1860733_5	479434.Sthe_1861	3.556e-118	404.0	COG1807@1|root,COG1807@2|Bacteria,2GB92@200795|Chloroflexi,27Y63@189775|Thermomicrobia	189775|Thermomicrobia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1860733_0	479434.Sthe_1860	2.739e-296	929.0	COG4745@1|root,COG4745@2|Bacteria,2G6HI@200795|Chloroflexi,27XK8@189775|Thermomicrobia	189775|Thermomicrobia	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_1860733_1	479434.Sthe_1234	1.19e-256	798.0	COG5476@1|root,COG5476@2|Bacteria,2G7N8@200795|Chloroflexi,27YXI@189775|Thermomicrobia	189775|Thermomicrobia	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
MMS3_k127_1860733_2	479434.Sthe_1859	1.707e-131	425.0	COG1806@1|root,COG1806@2|Bacteria,2G8E0@200795|Chloroflexi,27XGE@189775|Thermomicrobia	189775|Thermomicrobia	H	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
MMS3_k127_1860733_6	479434.Sthe_1856	1.368e-115	378.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,27XRQ@189775|Thermomicrobia	189775|Thermomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMS3_k127_1860733_8	479434.Sthe_1855	7.842e-62	225.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
MMS3_k127_1860733_4	479434.Sthe_1854	3.628e-120	403.0	COG1525@1|root,COG1525@2|Bacteria,2GBHE@200795|Chloroflexi,27YTT@189775|Thermomicrobia	189775|Thermomicrobia	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1860733_3	479434.Sthe_3503	2.613e-128	416.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	MA20_35610	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_1860733_7	479434.Sthe_1850	1.366e-103	345.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi,27XPG@189775|Thermomicrobia	189775|Thermomicrobia	L	Rad50 zinc hook motif	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
MMS3_k127_1865357_7	263358.VAB18032_29741	6.422e-51	186.0	COG0515@1|root,COG0515@2|Bacteria,2HMAN@201174|Actinobacteria,4DHS5@85008|Micromonosporales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
MMS3_k127_1865357_2	216594.MMAR_4170	2.055e-177	585.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2GKEU@201174|Actinobacteria,238B7@1762|Mycobacteriaceae	201174|Actinobacteria	TV	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
MMS3_k127_1865357_4	570952.ATVH01000017_gene1662	7.408e-154	507.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2JQP4@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase B/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydantoinase_B
MMS3_k127_1865357_3	479434.Sthe_2892	4.671e-162	534.0	COG0145@1|root,COG0145@2|Bacteria,2G7YY@200795|Chloroflexi,27ZD4@189775|Thermomicrobia	2|Bacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	oplaH	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
MMS3_k127_1865357_0	479434.Sthe_3515	9.07e-263	824.0	COG0028@1|root,COG0028@2|Bacteria,2G9ZD@200795|Chloroflexi,27XQW@189775|Thermomicrobia	189775|Thermomicrobia	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_1865357_1	1123023.JIAI01000001_gene6965	3.582e-217	688.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4E05J@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase, CocE NonD family	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_1865357_5	1521187.JPIM01000017_gene324	5.399e-97	324.0	COG1718@1|root,COG1718@2|Bacteria,2G81S@200795|Chloroflexi	200795|Chloroflexi	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1865357_8	378806.STAUR_8011	8.208e-35	137.0	2CP0Z@1|root,32SI8@2|Bacteria,1RK5X@1224|Proteobacteria,434SF@68525|delta/epsilon subdivisions,2X904@28221|Deltaproteobacteria,2Z0HI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
MMS3_k127_1865357_6	1123023.JIAI01000002_gene5703	6.048e-58	210.0	COG1028@1|root,COG1028@2|Bacteria,2I72Q@201174|Actinobacteria,4EBUG@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_1866987_0	479434.Sthe_3406	1.097e-307	977.0	COG0477@1|root,COG0642@1|root,COG0793@1|root,COG2199@1|root,COG2203@1|root,COG3437@1|root,COG0477@2|Bacteria,COG0793@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,27Y5Y@189775|Thermomicrobia	189775|Thermomicrobia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD
MMS3_k127_1866987_1	479434.Sthe_1127	4.475e-61	216.0	COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi,27XHM@189775|Thermomicrobia	189775|Thermomicrobia	F	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
MMS3_k127_1877131_3	309801.trd_0771	1.652e-08	56.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi,27Y2D@189775|Thermomicrobia	189775|Thermomicrobia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
MMS3_k127_1877131_1	479434.Sthe_1260	9.02e-90	304.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi,27XEP@189775|Thermomicrobia	189775|Thermomicrobia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
MMS3_k127_1877131_2	1382356.JQMP01000003_gene2497	2.568e-83	287.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,27XW5@189775|Thermomicrobia	189775|Thermomicrobia	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
MMS3_k127_1877131_0	479434.Sthe_1262	7.989e-181	573.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi,27Y0T@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
MMS3_k127_1879134_3	309801.trd_A0484	1.067e-42	162.0	2EN95@1|root,33FWY@2|Bacteria,2G9F3@200795|Chloroflexi,27YP6@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1879134_1	479434.Sthe_3469	1.717e-95	317.0	COG0171@1|root,COG0171@2|Bacteria,2G5QP@200795|Chloroflexi,27YNR@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
MMS3_k127_1879134_0	479434.Sthe_2909	8.438e-219	688.0	COG1012@1|root,COG1012@2|Bacteria,2G7YU@200795|Chloroflexi,27Y0H@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMS3_k127_1879134_2	251229.Chro_1416	3.871e-88	295.0	COG3340@1|root,COG3340@2|Bacteria,1G6TI@1117|Cyanobacteria,3VMJQ@52604|Pleurocapsales	1117|Cyanobacteria	E	Peptidase family S51	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S51
MMS3_k127_1883780_0	479434.Sthe_2925	8.824e-197	631.0	COG0747@1|root,COG0747@2|Bacteria,2GA2U@200795|Chloroflexi,27YVV@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_1883780_1	479434.Sthe_1550	2.806e-96	328.0	COG0392@1|root,COG0392@2|Bacteria,2G6EN@200795|Chloroflexi,27Y9Q@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
MMS3_k127_1886053_4	706191.PANA_4045	2.114e-31	130.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,1RNBC@1236|Gammaproteobacteria,3VZAG@53335|Pantoea	1236|Gammaproteobacteria	EP	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K13891	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	-	BPD_transp_1,OppC_N
MMS3_k127_1886053_1	1038858.AXBA01000045_gene1305	4.925e-80	277.0	COG0601@1|root,COG0601@2|Bacteria,1NPPN@1224|Proteobacteria,2U0WG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_1886053_0	1003200.AXXA_25535	1.374e-97	341.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VKA4@28216|Betaproteobacteria,3T7IS@506|Alcaligenaceae	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_1886053_2	484770.UFO1_1169	1.803e-53	196.0	COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,4H344@909932|Negativicutes	909932|Negativicutes	H	PFAM Dimethylmenaquinone methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
MMS3_k127_1886053_3	1122925.KB895381_gene3954	5.571e-51	189.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,4HBS6@91061|Bacilli,26WKA@186822|Paenibacillaceae	91061|Bacilli	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_1896669_0	479434.Sthe_2751	2.442e-121	404.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_1896669_6	1417296.U879_09245	2.032e-05	49.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2U515@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
MMS3_k127_1896669_2	345341.KUTG_09020	2.206e-84	288.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4DZTQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
MMS3_k127_1896669_5	113355.CM001775_gene3637	4.616e-15	76.0	COG1724@1|root,COG1724@2|Bacteria,1G9GU@1117|Cyanobacteria	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
MMS3_k127_1896669_4	272134.KB731324_gene1664	1.941e-24	106.0	COG1598@1|root,COG1598@2|Bacteria,1G9Q6@1117|Cyanobacteria,1HG3X@1150|Oscillatoriales	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
MMS3_k127_1896669_3	479434.Sthe_2591	7.982e-67	243.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_1896669_1	285535.JOEY01000025_gene9758	3.149e-119	392.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_1907739_4	926569.ANT_06080	1.921e-49	187.0	COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_1907739_5	234267.Acid_2155	3.8e-11	70.0	2E65M@1|root,330UB@2|Bacteria	2|Bacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_1907739_1	928724.SacglDRAFT_03170	3.312e-102	339.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,4E2HG@85010|Pseudonocardiales	201174|Actinobacteria	C	F420-dependent oxidoreductase, MSMEG_2906 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_1907739_2	479434.Sthe_3033	8.386e-68	235.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
MMS3_k127_1907739_0	479434.Sthe_3300	1.124e-167	540.0	COG0665@1|root,COG0665@2|Bacteria,2G86Q@200795|Chloroflexi,27Y37@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_1907739_3	1157708.KB907458_gene1957	1.661e-65	229.0	COG1171@1|root,COG1171@2|Bacteria,1MW2Q@1224|Proteobacteria,2VK9P@28216|Betaproteobacteria,4AACF@80864|Comamonadaceae	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_1912464_14	1382356.JQMP01000003_gene2120	8.201e-47	183.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
MMS3_k127_1912464_1	479434.Sthe_2455	8.835e-203	641.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi,27Y1Y@189775|Thermomicrobia	189775|Thermomicrobia	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
MMS3_k127_1912464_9	479434.Sthe_2442	1.799e-69	237.0	COG1729@1|root,COG1729@2|Bacteria,2GA5A@200795|Chloroflexi,27ZAX@189775|Thermomicrobia	189775|Thermomicrobia	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1912464_2	479434.Sthe_2446	1.979e-170	545.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_1912464_11	351607.Acel_0043	1.9e-50	192.0	COG2267@1|root,COG2267@2|Bacteria,2IGKW@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
MMS3_k127_1912464_10	298654.FraEuI1c_5974	1.076e-68	241.0	COG1277@1|root,COG1277@2|Bacteria,2GJ2R@201174|Actinobacteria	201174|Actinobacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
MMS3_k127_1912464_3	390989.JOEG01000001_gene4861	1.71e-152	499.0	COG3506@1|root,COG3506@2|Bacteria,2GN5A@201174|Actinobacteria,4DAIW@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_1912464_4	749414.SBI_05116	1.797e-125	409.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_1912464_5	365528.KB891261_gene456	1.301e-107	352.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4ETTD@85013|Frankiales	201174|Actinobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_1912464_7	365528.KB891261_gene457	8.49e-95	323.0	COG0642@1|root,COG0642@2|Bacteria,2I436@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1912464_0	479434.Sthe_2416	4.927e-250	776.0	COG0174@1|root,COG0174@2|Bacteria,2G5U2@200795|Chloroflexi,27XSZ@189775|Thermomicrobia	189775|Thermomicrobia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
MMS3_k127_1912464_12	479434.Sthe_3187	8.102e-50	184.0	COG3871@1|root,COG3871@2|Bacteria,2G9DN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
MMS3_k127_1912464_6	485913.Krac_6303	1.953e-96	329.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_1916032_0	479434.Sthe_1312	1.928e-177	562.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,27XHQ@189775|Thermomicrobia	189775|Thermomicrobia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
MMS3_k127_1916032_1	479434.Sthe_1310	1.632e-127	419.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi,27XJY@189775|Thermomicrobia	189775|Thermomicrobia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
MMS3_k127_1924667_1	479434.Sthe_1298	6.345e-123	401.0	COG0769@1|root,COG0769@2|Bacteria,2G944@200795|Chloroflexi,27Y91@189775|Thermomicrobia	189775|Thermomicrobia	M	Mur ligase, middle domain protein	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	-
MMS3_k127_1924667_4	479434.Sthe_1297	1.629e-66	232.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi,27YEQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
MMS3_k127_1924667_2	479434.Sthe_1296	6.033e-98	326.0	COG0084@1|root,COG0084@2|Bacteria,2G6F2@200795|Chloroflexi,27Y6N@189775|Thermomicrobia	189775|Thermomicrobia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
MMS3_k127_1924667_0	479434.Sthe_1295	9.147e-283	881.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi,27XFD@189775|Thermomicrobia	189775|Thermomicrobia	M	Glutamine amidotransferase domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
MMS3_k127_1924667_3	479434.Sthe_1294	8.6e-83	281.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi,27Y2T@189775|Thermomicrobia	2|Bacteria	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
MMS3_k127_1926905_8	1382306.JNIM01000001_gene284	4.101e-46	173.0	COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_1926905_1	479434.Sthe_0763	4.658e-267	828.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi,27XS3@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMS3_k127_1926905_2	479434.Sthe_0764	6.784e-231	720.0	COG0065@1|root,COG0065@2|Bacteria,2G5IZ@200795|Chloroflexi,27Y24@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
MMS3_k127_1926905_6	1382356.JQMP01000004_gene595	3.768e-73	255.0	COG0066@1|root,COG0066@2|Bacteria,2G6PB@200795|Chloroflexi,27Y7V@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the LeuD family	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
MMS3_k127_1926905_4	479434.Sthe_0766	5.281e-151	488.0	COG0473@1|root,COG0473@2|Bacteria,2G63C@200795|Chloroflexi,27XNJ@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS3_k127_1926905_10	1385514.N782_17680	2.711e-19	97.0	COG3220@1|root,COG3220@2|Bacteria,1V7A9@1239|Firmicutes,4HNZF@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF692)	-	-	-	-	-	-	-	-	-	-	-	-	DUF692
MMS3_k127_1926905_7	479434.Sthe_0767	3.051e-57	201.0	COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi,27YEW@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
MMS3_k127_1926905_9	356851.JOAN01000002_gene845	4.073e-24	108.0	COG0537@1|root,COG0537@2|Bacteria,2IMBA@201174|Actinobacteria,4DEFU@85008|Micromonosporales	201174|Actinobacteria	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
MMS3_k127_1926905_5	1382356.JQMP01000004_gene12	7.035e-84	291.0	COG2362@1|root,COG2362@2|Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
MMS3_k127_1926905_0	479434.Sthe_0770	0.0	1380.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi,27Y4S@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMS3_k127_1926905_3	479434.Sthe_0771	4.809e-223	701.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,27Y2J@189775|Thermomicrobia	189775|Thermomicrobia	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
MMS3_k127_1927366_5	1196028.ALEF01000035_gene982	1.231e-56	203.0	COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,4HC1C@91061|Bacilli,4C6C0@84406|Virgibacillus	91061|Bacilli	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
MMS3_k127_1927366_1	868595.Desca_2498	9.591e-141	456.0	COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,24A65@186801|Clostridia,266Q3@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
MMS3_k127_1927366_0	1281779.H009_11666	1.048e-221	698.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TRBN@28211|Alphaproteobacteria,4BBMU@82115|Rhizobiaceae	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_1927366_2	374847.Kcr_0933	1.031e-114	377.0	COG4608@1|root,arCOG00184@2157|Archaea	2157|Archaea	E	COG4608 ABC-type oligopeptide transport system, ATPase component	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
MMS3_k127_1927366_3	342949.PNA2_0675	1.572e-95	324.0	COG0444@1|root,arCOG00181@2157|Archaea,2XSTM@28890|Euryarchaeota,244YG@183968|Thermococci	183968|Thermococci	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMS3_k127_1927366_4	1028800.RG540_CH35190	7.604e-90	301.0	COG1173@1|root,COG1173@2|Bacteria,1PGNP@1224|Proteobacteria,2V8SA@28211|Alphaproteobacteria,4BDEZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_1931798_4	479434.Sthe_1586	3.713e-63	222.0	COG3808@1|root,COG3808@2|Bacteria,2G5N7@200795|Chloroflexi,27XGS@189775|Thermomicrobia	189775|Thermomicrobia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
MMS3_k127_1931798_5	479434.Sthe_1585	6.969e-17	85.0	2EKS3@1|root,33EFV@2|Bacteria,2GBBM@200795|Chloroflexi,27YP9@189775|Thermomicrobia	189775|Thermomicrobia	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
MMS3_k127_1931798_3	479434.Sthe_1584	1.084e-79	270.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi,27YE2@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
MMS3_k127_1931798_0	479434.Sthe_1583	5.682e-295	915.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,27XSC@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
MMS3_k127_1931798_2	1382356.JQMP01000004_gene54	7.037e-111	368.0	COG1622@1|root,COG1622@2|Bacteria,2G6C0@200795|Chloroflexi,27XKX@189775|Thermomicrobia	189775|Thermomicrobia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
MMS3_k127_1931798_1	479434.Sthe_1581	1.397e-173	547.0	COG0365@1|root,COG0365@2|Bacteria,2G5KE@200795|Chloroflexi,27XEK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS3_k127_1938355_2	479434.Sthe_0626	1.854e-79	273.0	COG0546@1|root,COG0546@2|Bacteria,2G9CI@200795|Chloroflexi,27YAX@189775|Thermomicrobia	200795|Chloroflexi	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
MMS3_k127_1938355_1	479434.Sthe_0625	1.17e-91	305.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi,27Y0R@189775|Thermomicrobia	189775|Thermomicrobia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMS3_k127_1938355_0	937777.Deipe_2162	1.355e-93	316.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
MMS3_k127_1967309_1	525904.Tter_0418	1.422e-145	485.0	COG4166@1|root,COG4166@2|Bacteria,2NQQP@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
MMS3_k127_1967309_0	1382356.JQMP01000004_gene184	1.088e-153	492.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27XFR@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_197064_2	479434.Sthe_3326	2.02e-92	308.0	COG4974@1|root,COG4974@2|Bacteria,2G94T@200795|Chloroflexi,27XHI@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_197064_1	479434.Sthe_3325	8.167e-94	315.0	COG0671@1|root,COG0671@2|Bacteria,2GB9M@200795|Chloroflexi,27YCA@189775|Thermomicrobia	189775|Thermomicrobia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
MMS3_k127_197064_4	479434.Sthe_3324	1.073e-77	264.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.11.1,3.5.1.19	ko:K08281,ko:K12132	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000,ko01001	-	-	iE2348C_1286.E2348C_1895,iECs_1301.ECs2475,iZ_1308.Z2802	Isochorismatase
MMS3_k127_197064_5	479434.Sthe_3323	2.294e-17	89.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
MMS3_k127_197064_3	479434.Sthe_3322	1.337e-80	284.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	2.7.11.1,3.4.21.107	ko:K04771,ko:K07090,ko:K14949	ko01503,ko02020,ko05152,map01503,map02020,map05152	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko03110	-	-	-	Trypsin_2
MMS3_k127_197064_0	479434.Sthe_3321	1.511e-111	368.0	COG1134@1|root,COG1134@2|Bacteria,2G6D9@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM ABC transporter related	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
MMS3_k127_1978269_3	479434.Sthe_0704	2.202e-31	124.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi,27YG7@189775|Thermomicrobia	189775|Thermomicrobia	S	Stage V sporulation protein S (SpoVS)	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
MMS3_k127_1978269_0	479434.Sthe_0703	4.994e-238	747.0	COG1418@1|root,COG1418@2|Bacteria,2G620@200795|Chloroflexi,27Y2Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
MMS3_k127_1978269_1	479434.Sthe_0701	5.099e-236	743.0	COG1574@1|root,COG1574@2|Bacteria,2G85Y@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_1978269_4	479434.Sthe_0700	2.653e-28	118.0	2E63U@1|root,330SV@2|Bacteria,2G9KB@200795|Chloroflexi,27YPM@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1978269_2	479434.Sthe_0413	2.894e-94	317.0	COG0477@1|root,COG2814@2|Bacteria,2G8SG@200795|Chloroflexi,27XS0@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1979192_0	479434.Sthe_2668	0.0	1472.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_1979192_1	1123288.SOV_1c05550	8.216e-13	73.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4H7ZK@909932|Negativicutes	909932|Negativicutes	E	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_1979985_7	1081640.AGFU01000051_gene860	1.452e-31	138.0	COG2885@1|root,COG3210@1|root,COG3391@1|root,COG3468@1|root,COG4625@1|root,COG2885@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3468@2|Bacteria,COG4625@2|Bacteria,1QUXB@1224|Proteobacteria,2TX5F@28211|Alphaproteobacteria,2KEGN@204457|Sphingomonadales	204457|Sphingomonadales	MU	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,He_PIG,TIG
MMS3_k127_1979985_2	485913.Krac_3359	8.138e-142	469.0	COG0477@1|root,COG2814@2|Bacteria,2G814@200795|Chloroflexi	2|Bacteria	P	SPTR A9B396 Drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_1979985_4	479434.Sthe_2914	1.462e-110	361.0	COG1670@1|root,COG1670@2|Bacteria,2G6X6@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_1979985_3	479434.Sthe_2024	6.449e-140	456.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2G698@200795|Chloroflexi,27YAJ@189775|Thermomicrobia	189775|Thermomicrobia	E	Cysteine synthase	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_1979985_9	221288.JH992901_gene5628	1.163e-10	64.0	COG1598@1|root,COG1598@2|Bacteria,1G978@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1979985_5	204669.Acid345_0955	1.295e-50	183.0	COG5483@1|root,COG5483@2|Bacteria	2|Bacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
MMS3_k127_1979985_1	479434.Sthe_2461	3.374e-146	471.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi,27XYH@189775|Thermomicrobia	189775|Thermomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
MMS3_k127_1979985_0	479434.Sthe_2141	3.783e-163	541.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	200795|Chloroflexi	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
MMS3_k127_1979985_6	479434.Sthe_2141	1.312e-47	178.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	200795|Chloroflexi	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
MMS3_k127_1979985_8	136273.GY22_14975	6.828e-11	67.0	2DRQB@1|root,33CKR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1999458_0	864069.MicloDRAFT_00001320	1.38e-171	550.0	COG1409@1|root,COG1409@2|Bacteria,1PNXB@1224|Proteobacteria,2U4JF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
MMS3_k127_1999458_1	266117.Rxyl_2783	8.514e-49	185.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,2GIZF@201174|Actinobacteria,4CRHY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
MMS3_k127_199954_4	714083.JH370377_gene757	6.415e-11	70.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
MMS3_k127_199954_3	316274.Haur_0049	1.314e-57	208.0	COG0664@1|root,COG0664@2|Bacteria,2GAUQ@200795|Chloroflexi,377NH@32061|Chloroflexia	32061|Chloroflexia	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_199954_1	221288.JH992901_gene1603	1.1e-68	243.0	COG3173@1|root,COG3173@2|Bacteria,1GKJB@1117|Cyanobacteria,1JMB4@1189|Stigonemataceae	1117|Cyanobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_199954_2	1198452.Jab_2c34270	1.298e-59	215.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VMB3@28216|Betaproteobacteria,4779T@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_199954_0	1205910.B005_1787	1.261e-241	756.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EG29@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_199954_5	1173020.Cha6605_2163	2.738e-06	50.0	COG0789@1|root,COG0789@2|Bacteria,1G5E7@1117|Cyanobacteria	1117|Cyanobacteria	K	MerR family regulatory protein	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	Clp_N,MerR_1,TipAS
MMS3_k127_1999753_7	479434.Sthe_1415	2.489e-13	71.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi,27Y17@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
MMS3_k127_1999753_6	479434.Sthe_1416	1.443e-41	158.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi,27YD4@189775|Thermomicrobia	189775|Thermomicrobia	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
MMS3_k127_1999753_5	479434.Sthe_1417	2.612e-46	171.0	2ER5R@1|root,33IRB@2|Bacteria,2G9QX@200795|Chloroflexi,27YKZ@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_1999753_2	1379698.RBG1_1C00001G1619	1.276e-53	197.0	COG0785@1|root,COG0785@2|Bacteria,2NPE4@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
MMS3_k127_1999753_4	479434.Sthe_1418	2.557e-47	177.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi,27YDN@189775|Thermomicrobia	189775|Thermomicrobia	CO	Thioredoxin-like	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
MMS3_k127_1999753_1	479434.Sthe_1419	3.091e-219	686.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi,27XF5@189775|Thermomicrobia	189775|Thermomicrobia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
MMS3_k127_1999753_3	479434.Sthe_1420	5.518e-52	187.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi,27YCZ@189775|Thermomicrobia	189775|Thermomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
MMS3_k127_1999753_0	1382356.JQMP01000004_gene249	6.005e-222	690.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi,27XYE@189775|Thermomicrobia	189775|Thermomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
MMS3_k127_2001466_1	479434.Sthe_2005	1.284e-278	862.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,27YUV@189775|Thermomicrobia	189775|Thermomicrobia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
MMS3_k127_2001466_21	882083.SacmaDRAFT_2677	0.0002709	52.0	COG0761@1|root,COG0775@1|root,COG0761@2|Bacteria,COG0775@2|Bacteria,2GIZ7@201174|Actinobacteria,4DZDW@85010|Pseudonocardiales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB,PNP_UDP_1
MMS3_k127_2001466_15	335543.Sfum_0864	3.141e-70	251.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2MQQF@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	NmrA-like family	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
MMS3_k127_2001466_7	351607.Acel_1699	8.4e-166	528.0	COG0535@1|root,COG0535@2|Bacteria,2HTDD@201174|Actinobacteria,4ES4M@85013|Frankiales	201174|Actinobacteria	F	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_14,Radical_SAM
MMS3_k127_2001466_5	479434.Sthe_2006	9.824e-203	642.0	COG0432@1|root,COG1304@1|root,COG0432@2|Bacteria,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
MMS3_k127_2001466_16	521098.Aaci_2442	5.22e-58	214.0	COG1562@1|root,COG1562@2|Bacteria	2|Bacteria	I	ergosterol biosynthetic process	hpnC	-	2.5.1.32,2.5.1.99,4.2.3.156	ko:K02291,ko:K21679	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
MMS3_k127_2001466_17	1996.JOFO01000020_gene2414	4.543e-56	210.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4EIHH@85012|Streptosporangiales	201174|Actinobacteria	I	Squalene/phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
MMS3_k127_2001466_13	1120948.KB903246_gene3315	2.777e-76	272.0	COG1232@1|root,COG1232@2|Bacteria,2I2Z5@201174|Actinobacteria,4E1XZ@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM squalene-associated FAD-dependent desaturase	hopC	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMS3_k127_2001466_0	479434.Sthe_2007	2.006e-290	902.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	shc	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
MMS3_k127_2001466_3	479434.Sthe_2008	1.033e-266	830.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi,27XPT@189775|Thermomicrobia	189775|Thermomicrobia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
MMS3_k127_2001466_18	479434.Sthe_2009	1.235e-51	185.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi,27YM9@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
MMS3_k127_2001466_19	479434.Sthe_2010	7.383e-32	126.0	COG0851@1|root,COG0851@2|Bacteria,2G7FM@200795|Chloroflexi,27YPY@189775|Thermomicrobia	189775|Thermomicrobia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	-	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
MMS3_k127_2001466_8	479434.Sthe_2011	1.301e-148	473.0	COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi,27Y4U@189775|Thermomicrobia	189775|Thermomicrobia	D	VirC1 protein	-	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA
MMS3_k127_2001466_10	479434.Sthe_2012	9.395e-97	323.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi,27YGI@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
MMS3_k127_2001466_2	479434.Sthe_2013	7.513e-278	873.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi,27Y4X@189775|Thermomicrobia	189775|Thermomicrobia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMS3_k127_2001466_20	1382356.JQMP01000004_gene483	7.142e-22	101.0	COG2891@1|root,COG2891@2|Bacteria,2GBC9@200795|Chloroflexi,27YRC@189775|Thermomicrobia	189775|Thermomicrobia	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	MreD
MMS3_k127_2001466_12	479434.Sthe_0147	4.217e-85	290.0	COG0639@1|root,COG0639@2|Bacteria,2G71P@200795|Chloroflexi,27Y85@189775|Thermomicrobia	189775|Thermomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_2001466_9	479434.Sthe_0146	1.367e-119	389.0	COG3442@1|root,COG3442@2|Bacteria,2G6KU@200795|Chloroflexi,27XXH@189775|Thermomicrobia	189775|Thermomicrobia	H	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
MMS3_k127_2001466_6	479434.Sthe_0145	1.237e-188	601.0	COG0771@1|root,COG0771@2|Bacteria,2GBHB@200795|Chloroflexi,27XXI@189775|Thermomicrobia	189775|Thermomicrobia	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
MMS3_k127_2001466_14	479434.Sthe_0144	4.23e-75	263.0	COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi,27YGP@189775|Thermomicrobia	189775|Thermomicrobia	M	Involved in formation and maintenance of cell shape	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
MMS3_k127_2001466_4	479434.Sthe_0143	6.557e-208	651.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi,27XN7@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS3_k127_2001466_11	479434.Sthe_0140	1.174e-85	291.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,27XHE@189775|Thermomicrobia	189775|Thermomicrobia	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
MMS3_k127_2007232_1	1120949.KB903313_gene494	1.858e-75	255.0	COG0251@1|root,COG0251@2|Bacteria,2GQ40@201174|Actinobacteria	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
MMS3_k127_2007232_0	6500.XP_005092325.1	2.277e-110	365.0	COG1171@1|root,KOG1251@2759|Eukaryota,3AJVW@33154|Opisthokonta,3BZSW@33208|Metazoa,3DG6W@33213|Bilateria	33208|Metazoa	ET	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
MMS3_k127_2009924_5	941449.dsx2_2701	2.047e-29	127.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,42S04@68525|delta/epsilon subdivisions,2WP08@28221|Deltaproteobacteria,2MGXB@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
MMS3_k127_2009924_3	273057.SSO2128	2.906e-102	345.0	COG1144@1|root,arCOG01604@2157|Archaea,2XRKM@28889|Crenarchaeota	28889|Crenarchaeota	C	Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like)	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_21
MMS3_k127_2009924_1	266117.Rxyl_0920	4.314e-149	483.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
MMS3_k127_2009924_2	273057.SSO2130	1.481e-133	433.0	COG1013@1|root,arCOG01601@2157|Archaea,2XPVE@28889|Crenarchaeota	28889|Crenarchaeota	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_2009924_6	565033.GACE_0183	1.544e-16	83.0	COG1669@1|root,arCOG01206@2157|Archaea,2Y02Z@28890|Euryarchaeota,246IH@183980|Archaeoglobi	183980|Archaeoglobi	S	DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
MMS3_k127_2009924_4	357808.RoseRS_0548	1.294e-30	124.0	COG2361@1|root,COG2361@2|Bacteria,2G8W4@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
MMS3_k127_2009924_0	479434.Sthe_2121	4.339e-260	809.0	COG2609@1|root,COG2609@2|Bacteria,2G7U8@200795|Chloroflexi	200795|Chloroflexi	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
MMS3_k127_2012027_7	479434.Sthe_0130	2.465e-06	49.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi	200795|Chloroflexi	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_2012027_0	479434.Sthe_2733	5.461e-171	545.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi,27XEV@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2012027_6	1286171.EAL2_c18930	1.709e-07	61.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,25WNV@186806|Eubacteriaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
MMS3_k127_2012027_1	479434.Sthe_2731	9.7e-86	292.0	COG3944@1|root,COG3944@2|Bacteria	2|Bacteria	M	capsule polysaccharide biosynthetic process	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	GNVR,Wzz
MMS3_k127_2012027_3	479434.Sthe_2730	2.682e-66	234.0	COG0489@1|root,COG0489@2|Bacteria,2G5WM@200795|Chloroflexi,27Y7Y@189775|Thermomicrobia	189775|Thermomicrobia	DM	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2012027_2	479434.Sthe_2729	8.999e-69	241.0	COG1846@1|root,COG1846@2|Bacteria,2GB9V@200795|Chloroflexi,27YED@189775|Thermomicrobia	189775|Thermomicrobia	K	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
MMS3_k127_2012027_4	688270.Celal_1655	1.883e-28	117.0	COG0668@1|root,COG0668@2|Bacteria,4NFX6@976|Bacteroidetes,1HWPR@117743|Flavobacteriia,1F9ZP@104264|Cellulophaga	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
MMS3_k127_2016470_0	479434.Sthe_1906	1.052e-228	724.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,27XT4@189775|Thermomicrobia	189775|Thermomicrobia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
MMS3_k127_2016470_2	479434.Sthe_1905	1.45e-87	299.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,27YU3@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
MMS3_k127_2016470_1	479434.Sthe_1903	3.244e-177	572.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi,27YA9@189775|Thermomicrobia	189775|Thermomicrobia	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
MMS3_k127_2031690_1	479434.Sthe_1462	2.65e-196	627.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi,27Y2G@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_2031690_4	1380390.JIAT01000009_gene2254	7.211e-09	60.0	COG4934@1|root,COG4934@2|Bacteria,2GMZ8@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase S53	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_S8
MMS3_k127_2031690_2	1156844.KB891842_gene7479	5.15e-62	220.0	COG0346@1|root,COG0346@2|Bacteria,2I8Q5@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Aminoglyc_resit
MMS3_k127_2031690_0	479434.Sthe_3372	1.994e-205	650.0	COG2079@1|root,COG2079@2|Bacteria,2G8X4@200795|Chloroflexi,27Z98@189775|Thermomicrobia	189775|Thermomicrobia	S	MmgE/PrpD family	-	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
MMS3_k127_2031690_3	479434.Sthe_3365	5.61e-58	206.0	COG1131@1|root,COG1131@2|Bacteria,2G6JW@200795|Chloroflexi,27YZ8@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2033090_0	479434.Sthe_0845	2.074e-295	912.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi,27Y1U@189775|Thermomicrobia	189775|Thermomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
MMS3_k127_2033090_8	309801.trd_1301	1.646e-39	149.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi,27YJ2@189775|Thermomicrobia	189775|Thermomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
MMS3_k127_2033090_2	479434.Sthe_0843	5.176e-182	576.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27XZ4@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_2033090_4	479434.Sthe_0840	7.503e-126	409.0	COG0327@1|root,COG0327@2|Bacteria,2G9ZR@200795|Chloroflexi,27XXV@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2033090_3	479434.Sthe_0838	5.059e-148	474.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi,27XGA@189775|Thermomicrobia	189775|Thermomicrobia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
MMS3_k127_2033090_5	479434.Sthe_0837	7.7e-89	302.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi,27XUP@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
MMS3_k127_2033090_6	479434.Sthe_0836	3.649e-73	258.0	COG1947@1|root,COG1947@2|Bacteria,2G71D@200795|Chloroflexi,27Y5K@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
MMS3_k127_2033090_7	479434.Sthe_0834	3.213e-46	173.0	COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi,27Z8E@189775|Thermomicrobia	189775|Thermomicrobia	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_2033090_1	479434.Sthe_0833	6.103e-230	728.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
MMS3_k127_2033090_9	309801.trd_1314	6.958e-29	127.0	COG2333@1|root,COG2333@2|Bacteria,2GA5M@200795|Chloroflexi,27ZBF@189775|Thermomicrobia	189775|Thermomicrobia	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2035813_3	479434.Sthe_1563	6.78e-76	263.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia	2|Bacteria	S	Belongs to the peptidase M50B family	VVA0737	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
MMS3_k127_2035813_0	479434.Sthe_1564	2.518e-186	591.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,27XK0@189775|Thermomicrobia	189775|Thermomicrobia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
MMS3_k127_2035813_5	479434.Sthe_1565	3.1e-37	143.0	COG2018@1|root,COG2018@2|Bacteria,2G7BR@200795|Chloroflexi,27YND@189775|Thermomicrobia	189775|Thermomicrobia	S	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
MMS3_k127_2035813_1	479434.Sthe_1566	2.386e-126	415.0	COG0150@1|root,COG0150@2|Bacteria,2G5YZ@200795|Chloroflexi,27Y07@189775|Thermomicrobia	189775|Thermomicrobia	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_2035813_4	479434.Sthe_1567	4.572e-66	231.0	COG2018@1|root,COG2018@2|Bacteria,2GACP@200795|Chloroflexi,27ZBT@189775|Thermomicrobia	189775|Thermomicrobia	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
MMS3_k127_2035813_2	479434.Sthe_1568	1.208e-110	359.0	COG1100@1|root,COG1100@2|Bacteria,2G6A7@200795|Chloroflexi,27XH2@189775|Thermomicrobia	189775|Thermomicrobia	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
MMS3_k127_2036000_6	479434.Sthe_1549	7.859e-130	419.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,27XNM@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMS3_k127_2036000_5	479434.Sthe_1548	4.46e-140	452.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi,27XVI@189775|Thermomicrobia	189775|Thermomicrobia	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
MMS3_k127_2036000_1	479434.Sthe_1543	5.429e-236	736.0	COG2873@1|root,COG2873@2|Bacteria,2G5NS@200795|Chloroflexi,27XTM@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	CoA_binding_2,Cys_Met_Meta_PP
MMS3_k127_2036000_4	479434.Sthe_1542	1.574e-171	546.0	COG2021@1|root,COG2021@2|Bacteria,2G5JD@200795|Chloroflexi,27XTI@189775|Thermomicrobia	189775|Thermomicrobia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
MMS3_k127_2036000_8	1382356.JQMP01000003_gene2395	2.001e-104	353.0	COG5621@1|root,COG5621@2|Bacteria,2G6EI@200795|Chloroflexi,27YRR@189775|Thermomicrobia	189775|Thermomicrobia	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
MMS3_k127_2036000_0	309801.trd_0370	1.863e-265	836.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,27XX9@189775|Thermomicrobia	189775|Thermomicrobia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_2036000_9	479434.Sthe_1958	4.209e-78	270.0	COG0500@1|root,COG2226@2|Bacteria,2G6R0@200795|Chloroflexi,27Z68@189775|Thermomicrobia	189775|Thermomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2036000_7	479434.Sthe_1957	1.959e-126	417.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
MMS3_k127_2036000_3	479434.Sthe_1955	5.177e-172	546.0	COG3191@1|root,COG3191@2|Bacteria,2G83F@200795|Chloroflexi,27YT6@189775|Thermomicrobia	189775|Thermomicrobia	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
MMS3_k127_2036000_2	479434.Sthe_1953	3.669e-228	713.0	COG0380@1|root,COG0380@2|Bacteria,2G6F8@200795|Chloroflexi,27XTV@189775|Thermomicrobia	189775|Thermomicrobia	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
MMS3_k127_2051422_3	1521187.JPIM01000038_gene3831	3.083e-20	100.0	COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi,377CQ@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
MMS3_k127_2051422_5	525904.Tter_0098	1.152e-11	70.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
MMS3_k127_2051422_0	479434.Sthe_0191	4.696e-56	208.0	COG3662@1|root,COG3662@2|Bacteria,2G8VS@200795|Chloroflexi,27YAB@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
MMS3_k127_2051422_1	91464.S7335_3783	1.075e-47	178.0	COG0563@1|root,COG0563@2|Bacteria,1G696@1117|Cyanobacteria	1117|Cyanobacteria	F	COG0563 Adenylate kinase and related	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,PduV-EutP,SKI
MMS3_k127_2051422_4	525904.Tter_1488	9.06e-14	76.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_2051422_2	926560.KE387027_gene881	2.299e-45	171.0	COG0031@1|root,COG0031@2|Bacteria,1WJ3S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_2051579_4	309801.trd_A0629	2.034e-50	185.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
MMS3_k127_2051579_0	309801.trd_A0628	0.0	1582.0	COG0243@1|root,COG0243@2|Bacteria,2GABT@200795|Chloroflexi,27Z9X@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMS3_k127_2051579_12	690850.Desaf_1419	3.252e-08	56.0	2CEZQ@1|root,33C4G@2|Bacteria,1P9ED@1224|Proteobacteria,432EU@68525|delta/epsilon subdivisions,2WYJ9@28221|Deltaproteobacteria,2MFPC@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2051579_3	1440053.JOEI01000018_gene467	2.758e-65	235.0	COG0715@1|root,COG0715@2|Bacteria,2HZMX@201174|Actinobacteria	201174|Actinobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2051579_2	485913.Krac_2049	3.108e-164	543.0	COG1807@1|root,COG1807@2|Bacteria,2G6CP@200795|Chloroflexi	200795|Chloroflexi	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_2051579_9	1121342.AUCO01000010_gene2337	1.559e-28	132.0	COG5650@1|root,COG5650@2|Bacteria,1TQVD@1239|Firmicutes,25CFN@186801|Clostridia,36DSE@31979|Clostridiaceae	186801|Clostridia	S	integral membrane protein	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2
MMS3_k127_2051579_13	1476583.DEIPH_ctg001orf0045	3.086e-05	53.0	2E4CV@1|root,32Z89@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2680
MMS3_k127_2051579_5	373994.Riv7116_6009	5.112e-48	180.0	COG4639@1|root,COG4639@2|Bacteria,1G6ES@1117|Cyanobacteria,1HNH0@1161|Nostocales	1117|Cyanobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
MMS3_k127_2051579_11	926561.KB900617_gene1613	8.398e-10	70.0	COG3173@1|root,COG3173@2|Bacteria,1U6NE@1239|Firmicutes,2489R@186801|Clostridia	186801|Clostridia	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_2051579_8	1382356.JQMP01000001_gene879	3.786e-29	122.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi,27YN5@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS3_k127_2051579_1	479434.Sthe_2134	1.212e-175	562.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G84K@200795|Chloroflexi,27XSV@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
MMS3_k127_2051579_6	1382356.JQMP01000001_gene881	4.147e-47	173.0	COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi,27Z7D@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
MMS3_k127_2051579_10	309801.trd_A0832	2.462e-11	67.0	COG2331@1|root,COG2331@2|Bacteria,2G7IB@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_2051579_7	309801.trd_A0831	1.711e-38	148.0	COG0640@1|root,COG0640@2|Bacteria,2GA4N@200795|Chloroflexi,27Z88@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
MMS3_k127_2057537_3	485913.Krac_4874	1.223e-91	306.0	COG0745@1|root,COG0745@2|Bacteria,2G6MM@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_2057537_11	1395587.P364_0124115	0.0003061	52.0	2DZXU@1|root,32VMR@2|Bacteria,1VBBV@1239|Firmicutes,4HPWN@91061|Bacilli,26ZA3@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2057537_9	1499967.BAYZ01000185_gene4538	3.718e-23	104.0	COG5513@1|root,COG5513@2|Bacteria	2|Bacteria	G	serine-type aminopeptidase activity	-	-	-	ko:K02030,ko:K14475	ko05143,map05143	M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	Inhibitor_I42
MMS3_k127_2057537_5	1469607.KK073768_gene1446	5.955e-74	254.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,1HKGI@1161|Nostocales	1117|Cyanobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
MMS3_k127_2057537_0	1157490.EL26_09965	4.148e-183	582.0	COG3844@1|root,COG3844@2|Bacteria,1TQ8V@1239|Firmicutes,4HBE8@91061|Bacilli,279GB@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
MMS3_k127_2057537_10	1038867.AXAY01000003_gene3021	2.346e-20	106.0	COG0454@1|root,COG0456@2|Bacteria,1R418@1224|Proteobacteria,2U1QH@28211|Alphaproteobacteria,3JXJI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_2057537_6	44251.PDUR_20250	3.055e-71	245.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,26TEW@186822|Paenibacillaceae	91061|Bacilli	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
MMS3_k127_2057537_7	479434.Sthe_0082	1.945e-53	190.0	COG1943@1|root,COG1943@2|Bacteria,2G968@200795|Chloroflexi	200795|Chloroflexi	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
MMS3_k127_2057537_8	742733.HMPREF9469_00976	9.614e-36	148.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMS3_k127_2057537_2	1499967.BAYZ01000159_gene547	1.142e-98	344.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_2057537_1	1150474.JQJI01000033_gene1626	1.765e-113	375.0	COG0601@1|root,COG0601@2|Bacteria,2GCGS@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_2057537_4	1499967.BAYZ01000160_gene410	5.37e-89	302.0	COG1173@1|root,COG1173@2|Bacteria,2NQ14@2323|unclassified Bacteria	2|Bacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	dppC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_2059739_3	1118054.CAGW01000060_gene2566	3.775e-109	366.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_2059739_2	479434.Sthe_2747	1.439e-225	707.0	COG0624@1|root,COG0624@2|Bacteria,2G62C@200795|Chloroflexi,27XWR@189775|Thermomicrobia	2|Bacteria	E	peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_2059739_5	479434.Sthe_1133	1.999e-51	192.0	2DYB6@1|root,3490S@2|Bacteria	479434.Sthe_1133|-	S	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2059739_6	1131269.AQVV01000001_gene1432	7.798e-33	136.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung2	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_2059739_8	309801.trd_0152	1.143e-08	59.0	2EQM1@1|root,33I6Z@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
MMS3_k127_2059739_0	1499967.BAYZ01000118_gene3290	5.725e-319	998.0	COG0058@1|root,COG0058@2|Bacteria,2NNZS@2323|unclassified Bacteria	2|Bacteria	G	Carbohydrate phosphorylase	malP	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
MMS3_k127_2059739_1	479434.Sthe_1355	2.346e-228	713.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,27XV0@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMS3_k127_2059739_4	479434.Sthe_1356	1.541e-60	213.0	COG2306@1|root,COG2306@2|Bacteria,2GBPB@200795|Chloroflexi,27YHI@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
MMS3_k127_2059739_7	1128421.JAGA01000002_gene533	2.731e-24	104.0	COG3214@1|root,COG3214@2|Bacteria,2NQD2@2323|unclassified Bacteria	2|Bacteria	S	Winged helix DNA-binding domain	ycaQ	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
MMS3_k127_2069720_4	1121377.KB906421_gene3703	1.13e-46	175.0	2DM1Q@1|root,31BVP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2069720_1	479434.Sthe_2482	5.838e-281	870.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi,27XUU@189775|Thermomicrobia	189775|Thermomicrobia	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_2069720_2	1385520.N802_03785	1.006e-224	709.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria,4FFVK@85021|Intrasporangiaceae	201174|Actinobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
MMS3_k127_2069720_3	1385520.N802_03790	4.244e-142	466.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,2GMRD@201174|Actinobacteria,4FFVM@85021|Intrasporangiaceae	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
MMS3_k127_2069720_0	479434.Sthe_2481	1.219e-310	964.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	189775|Thermomicrobia	EQ	Hydantoinaseoxoprolinase domain protein	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_207253_3	411468.CLOSCI_02091	4.796e-22	106.0	28H77@1|root,2Z7JH@2|Bacteria,1UZ9E@1239|Firmicutes,247WR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_207253_2	525904.Tter_2568	2.644e-42	164.0	COG0426@1|root,COG0426@2|Bacteria	2|Bacteria	C	nitric oxide reductase activity	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Fer4,Lactamase_B
MMS3_k127_207253_0	1123371.ATXH01000009_gene1077	6.044e-118	389.0	COG0438@1|root,COG0438@2|Bacteria,2GHNP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_207253_4	398578.Daci_4406	1.482e-05	52.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2WHH7@28216|Betaproteobacteria,4ADF1@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
MMS3_k127_207253_1	1120949.KB903294_gene3893	5.73e-81	275.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4DEM5@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
MMS3_k127_2081222_0	479434.Sthe_3376	2.013e-136	447.0	COG0477@1|root,COG2814@2|Bacteria,2G8XB@200795|Chloroflexi,27Y3H@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2092385_2	1123237.Salmuc_03678	4.874e-110	372.0	COG2234@1|root,COG2234@2|Bacteria,1PF4S@1224|Proteobacteria,2U3SU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_2092385_8	748247.AZKH_3411	1.213e-22	102.0	COG4101@1|root,COG4101@2|Bacteria,1RIHD@1224|Proteobacteria,2VT14@28216|Betaproteobacteria,2KX4X@206389|Rhodocyclales	206389|Rhodocyclales	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_2092385_3	309801.trd_1095	7.422e-104	347.0	COG2159@1|root,COG2159@2|Bacteria,2G8UX@200795|Chloroflexi,27Z57@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
MMS3_k127_2092385_5	106370.Francci3_2659	1.022e-76	267.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4ET1B@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2092385_4	408672.NBCG_03678	2.104e-82	284.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4DUXS@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2092385_9	485913.Krac_3903	1.503e-18	93.0	2EACU@1|root,334GQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_2092385_6	118161.KB235922_gene4429	3.689e-68	241.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1G3NQ@1117|Cyanobacteria,3VKA6@52604|Pleurocapsales	1117|Cyanobacteria	KT	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
MMS3_k127_2092385_7	309801.trd_0950	3.427e-54	202.0	COG1234@1|root,COG1234@2|Bacteria,2GBGY@200795|Chloroflexi,27YCM@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMS3_k127_2092385_0	479434.Sthe_1978	5.447e-181	586.0	COG1807@1|root,COG1807@2|Bacteria,2G8QS@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_2092385_1	479434.Sthe_2505	7.996e-112	370.0	COG0589@1|root,COG0589@2|Bacteria,2GBUS@200795|Chloroflexi,27Z69@189775|Thermomicrobia	189775|Thermomicrobia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2092385_10	479434.Sthe_2503	2.915e-17	85.0	COG1853@1|root,COG1853@2|Bacteria,2G9BM@200795|Chloroflexi,27Z20@189775|Thermomicrobia	189775|Thermomicrobia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
MMS3_k127_2101339_2	471852.Tcur_3660	1.01e-57	203.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria,4EFQJ@85012|Streptosporangiales	201174|Actinobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
MMS3_k127_2101339_0	479435.Kfla_6986	6.076e-175	552.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4DP5R@85009|Propionibacteriales	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
MMS3_k127_2101339_1	105425.BBPL01000028_gene4077	2.926e-125	410.0	COG0180@1|root,COG0180@2|Bacteria,2IIAM@201174|Actinobacteria	201174|Actinobacteria	J	tRNA synthetases class I (W and Y)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_1b
MMS3_k127_2107852_12	479434.Sthe_1810	1.471e-74	252.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y4F@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_2107852_22	525904.Tter_1286	9.19e-15	79.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	wapA	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	AhpC-TSA,NHL,Thioredoxin_8
MMS3_k127_2107852_2	479434.Sthe_1814	5.26e-180	573.0	COG1999@1|root,COG3391@1|root,COG1999@2|Bacteria,COG3391@2|Bacteria,2GAQJ@200795|Chloroflexi,27XX5@189775|Thermomicrobia	189775|Thermomicrobia	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMS3_k127_2107852_14	552811.Dehly_0704	5.864e-57	207.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi,34CJY@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_2107852_13	196162.Noca_2942	3.489e-73	265.0	COG4585@1|root,COG4585@2|Bacteria,2HESU@201174|Actinobacteria,4DVT5@85009|Propionibacteriales	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
MMS3_k127_2107852_16	479434.Sthe_1815	6.137e-41	154.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi,27YK9@189775|Thermomicrobia	189775|Thermomicrobia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
MMS3_k127_2107852_0	479434.Sthe_1816	0.0	1127.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi,27Y1J@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
MMS3_k127_2107852_6	357808.RoseRS_0865	1.565e-123	413.0	COG0728@1|root,COG0728@2|Bacteria,2G87R@200795|Chloroflexi,3770K@32061|Chloroflexia	32061|Chloroflexia	S	virulence factor MVIN family protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMS3_k127_2107852_4	1173024.KI912148_gene3045	2.055e-153	490.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1JIY9@1189|Stigonemataceae	1117|Cyanobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_2107852_15	35841.BT1A1_2726	1.422e-50	195.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZDDG@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_2107852_19	926550.CLDAP_36940	1.065e-26	122.0	COG1309@1|root,COG1309@2|Bacteria,2G76J@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2107852_8	33876.JNXY01000029_gene2662	2.107e-105	352.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4D8QU@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2107852_10	485913.Krac_0236	1.811e-99	331.0	COG3293@1|root,COG3293@2|Bacteria,2G7YC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
MMS3_k127_2107852_20	33876.JNXY01000029_gene2661	8.784e-22	105.0	COG3559@1|root,COG3559@2|Bacteria	2|Bacteria	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_2107852_18	33876.JNXY01000029_gene2661	1.506e-34	140.0	COG3559@1|root,COG3559@2|Bacteria	2|Bacteria	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_2107852_21	33876.JNXY01000029_gene2661	1.912e-19	95.0	COG3559@1|root,COG3559@2|Bacteria	2|Bacteria	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_2107852_11	416591.Tlet_1576	4.984e-85	289.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_2107852_1	1214101.BN159_1215	5.014e-211	670.0	COG0457@1|root,COG0457@2|Bacteria,2HX8A@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
MMS3_k127_2107852_17	489825.LYNGBM3L_42390	7.61e-37	147.0	2ENZH@1|root,33GKD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2107852_5	309801.trd_0315	3.382e-130	427.0	COG1641@1|root,COG1641@2|Bacteria,2G5MP@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
MMS3_k127_2107852_3	479434.Sthe_1821	9.865e-161	516.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,27XRH@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
MMS3_k127_2107852_9	1157640.AQWO01000004_gene4919	6.571e-103	344.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria	201174|Actinobacteria	T	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
MMS3_k127_2107852_7	309801.trd_0311	1.173e-106	354.0	COG0684@1|root,COG0684@2|Bacteria,2GBDU@200795|Chloroflexi,27Z0W@189775|Thermomicrobia	189775|Thermomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
MMS3_k127_2107852_23	1265505.ATUG01000002_gene1171	1.389e-06	53.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,434EE@68525|delta/epsilon subdivisions,2WYRT@28221|Deltaproteobacteria,2MN3I@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
MMS3_k127_2113241_11	404589.Anae109_4284	5.508e-21	102.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_2113241_8	479434.Sthe_2667	9.255e-46	177.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2113241_0	1298863.AUEP01000004_gene2263	2.305e-208	655.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4DNVF@85009|Propionibacteriales	201174|Actinobacteria	E	O-acetylhomoserine	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_2113241_6	479433.Caci_6244	1.315e-65	227.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria	201174|Actinobacteria	S	CoA-binding	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
MMS3_k127_2113241_1	485913.Krac_6032	3.007e-147	491.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
MMS3_k127_2113241_5	485913.Krac_6031	1.904e-77	264.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_2113241_4	196162.Noca_0658	3.679e-110	362.0	COG0667@1|root,COG0667@2|Bacteria,2ICY2@201174|Actinobacteria,4DPHZ@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_2113241_10	743525.TSC_c11170	7.369e-24	108.0	2BVRK@1|root,2ZCUH@2|Bacteria,1WMAJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2113241_3	56107.Cylst_2613	2.717e-122	402.0	COG1520@1|root,COG1520@2|Bacteria,1GDEQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
MMS3_k127_2113241_9	926550.CLDAP_05380	6.38e-27	118.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
MMS3_k127_2113241_2	1463857.JOFZ01000001_gene5526	8.329e-124	415.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
MMS3_k127_2113241_7	479434.Sthe_0794	1.476e-51	202.0	COG3858@1|root,COG3858@2|Bacteria,2G7HP@200795|Chloroflexi,27XZM@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycoside hydrolase, family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
MMS3_k127_2115718_0	378806.STAUR_7280	1.149e-99	346.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2WTUE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
MMS3_k127_2115718_2	316058.RPB_2702	2.297e-09	63.0	COG2329@1|root,COG2329@2|Bacteria,1NDM8@1224|Proteobacteria,2UG48@28211|Alphaproteobacteria,3JYVV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative mono-oxygenase ydhR	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
MMS3_k127_2115718_1	479434.Sthe_3508	1.385e-38	145.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_2130796_0	479434.Sthe_1558	4.802e-316	979.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi,27XHJ@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
MMS3_k127_2130796_4	1303518.CCALI_02196	5.605e-91	312.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
MMS3_k127_2130796_1	1382356.JQMP01000001_gene979	4.456e-154	491.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi,27XRY@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMS3_k127_2130796_2	479434.Sthe_1113	1.072e-121	404.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi,27XRV@189775|Thermomicrobia	189775|Thermomicrobia	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
MMS3_k127_2130796_3	479434.Sthe_1114	8.153e-95	322.0	COG3597@1|root,COG3597@2|Bacteria,2G9CM@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
MMS3_k127_2141072_1	479434.Sthe_1986	1.06e-69	239.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi,27YBF@189775|Thermomicrobia	189775|Thermomicrobia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
MMS3_k127_2141072_0	479434.Sthe_1987	2.815e-205	642.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi,27XQV@189775|Thermomicrobia	189775|Thermomicrobia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMS3_k127_2141072_2	479434.Sthe_1988	5.988e-28	128.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
MMS3_k127_2141072_3	479434.Sthe_1989	1.221e-18	87.0	COG1589@1|root,COG1589@2|Bacteria,2G7FV@200795|Chloroflexi,27YKW@189775|Thermomicrobia	189775|Thermomicrobia	D	POTRA domain, FtsQ-type	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
MMS3_k127_2149_2	479434.Sthe_1189	3.9e-85	287.0	2BPWQ@1|root,32IQE@2|Bacteria,2GAA8@200795|Chloroflexi,27YBA@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
MMS3_k127_2149_0	479434.Sthe_1188	3.302e-249	781.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,27Z0B@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_2149_1	479434.Sthe_1187	2.739e-98	326.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi,27Z0P@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_2155192_0	479434.Sthe_0466	1.281e-145	466.0	COG0423@1|root,COG0423@2|Bacteria,2G62M@200795|Chloroflexi,27XGU@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of glycine to tRNA(Gly)	-	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
MMS3_k127_2155192_1	479434.Sthe_0467	3.722e-114	375.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi,27XFW@189775|Thermomicrobia	189775|Thermomicrobia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
MMS3_k127_2155192_3	479434.Sthe_0468	2.658e-57	212.0	COG1266@1|root,COG1266@2|Bacteria,2G9FI@200795|Chloroflexi,27YGJ@189775|Thermomicrobia	189775|Thermomicrobia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_2155192_2	479434.Sthe_0469	2.194e-97	337.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	DUF756,TED
MMS3_k127_2156743_5	479434.Sthe_2436	3.999e-39	146.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
MMS3_k127_2156743_2	479434.Sthe_2437	1.075e-97	333.0	COG3429@1|root,COG3429@2|Bacteria,2G6ZV@200795|Chloroflexi,27Y92@189775|Thermomicrobia	189775|Thermomicrobia	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
MMS3_k127_2156743_3	479434.Sthe_2438	3.82e-73	256.0	COG0363@1|root,COG0363@2|Bacteria,2G6S0@200795|Chloroflexi,27YBD@189775|Thermomicrobia	189775|Thermomicrobia	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
MMS3_k127_2156743_1	479434.Sthe_2201	2.05e-107	353.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_2156743_4	479434.Sthe_2196	1.425e-62	221.0	COG1051@1|root,COG1051@2|Bacteria,2G74M@200795|Chloroflexi,27YGS@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_2156743_0	479434.Sthe_2195	3.587e-108	357.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,27Z0A@189775|Thermomicrobia	189775|Thermomicrobia	H	Quinolinate phosphoribosyl transferase, N-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
MMS3_k127_2156743_6	316274.Haur_2835	0.0004584	47.0	2A42D@1|root,30SM6@2|Bacteria,2GAFV@200795|Chloroflexi,375ZW@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2161338_7	485913.Krac_10690	1.131e-74	256.0	29BBV@1|root,2ZCHD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
MMS3_k127_2161338_1	309801.trd_0447	2.625e-177	562.0	COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,27XXF@189775|Thermomicrobia	189775|Thermomicrobia	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
MMS3_k127_2161338_0	479434.Sthe_0601	6.885e-184	582.0	COG0654@1|root,COG0654@2|Bacteria	2|Bacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
MMS3_k127_2161338_8	1382306.JNIM01000001_gene1538	4.199e-51	184.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	pcaC	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
MMS3_k127_2161338_3	1382306.JNIM01000001_gene1537	2.214e-142	458.0	COG0346@1|root,COG0346@2|Bacteria,2G7JF@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
MMS3_k127_2161338_9	331869.BAL199_16098	1.312e-37	144.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
MMS3_k127_2161338_10	298653.Franean1_2763	1.051e-13	77.0	2EANN@1|root,334R5@2|Bacteria,2INMD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2161338_6	1382356.JQMP01000003_gene1829	4.533e-101	344.0	COG1840@1|root,COG1840@2|Bacteria,2GBNE@200795|Chloroflexi,27ZCW@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2161338_4	479434.Sthe_1353	3.418e-123	403.0	COG0613@1|root,COG0613@2|Bacteria,2G71S@200795|Chloroflexi,27XQC@189775|Thermomicrobia	189775|Thermomicrobia	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	-
MMS3_k127_2161338_2	479434.Sthe_0863	4.995e-173	547.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi,27Z0R@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
MMS3_k127_2161338_5	479434.Sthe_0862	6.071e-114	371.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
MMS3_k127_2161338_11	479434.Sthe_0860	7.545e-09	59.0	COG1216@1|root,COG1216@2|Bacteria,2G8PX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_2
MMS3_k127_2162323_0	479434.Sthe_2357	6.316e-206	649.0	COG2268@1|root,COG2268@2|Bacteria,2GBEI@200795|Chloroflexi,27Z5S@189775|Thermomicrobia	189775|Thermomicrobia	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
MMS3_k127_2162323_2	479434.Sthe_2356	3.592e-45	173.0	COG1585@1|root,COG1585@2|Bacteria,2G9JI@200795|Chloroflexi	200795|Chloroflexi	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2162323_3	1128421.JAGA01000003_gene3540	5.452e-16	87.0	2E4CV@1|root,32Z89@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2680
MMS3_k127_2162323_1	479434.Sthe_2038	4.983e-105	348.0	COG0500@1|root,COG2226@2|Bacteria,2G6GD@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
MMS3_k127_2165975_1	1121456.ATVA01000019_gene1287	3.473e-80	273.0	COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,1MZV9@1224|Proteobacteria,42PR0@68525|delta/epsilon subdivisions,2WNXR@28221|Deltaproteobacteria,2MG42@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep
MMS3_k127_2165975_0	443143.GM18_1433	3.972e-131	425.0	COG0673@1|root,COG0673@2|Bacteria,1PXE1@1224|Proteobacteria,42MSE@68525|delta/epsilon subdivisions,2WKIS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_217565_3	525904.Tter_0767	0.0001651	44.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
MMS3_k127_217565_1	479434.Sthe_1172	1.91e-83	281.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi,27YJM@189775|Thermomicrobia	189775|Thermomicrobia	J	Translation initiation factor IF-3, C-terminal domain	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C
MMS3_k127_217565_0	479434.Sthe_1173	5.99e-208	672.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi,27Y2W@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
MMS3_k127_217565_2	479434.Sthe_1174	1.775e-64	226.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi,27Y0P@189775|Thermomicrobia	189775|Thermomicrobia	M	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2
MMS3_k127_2175912_8	479434.Sthe_1715	1.028e-55	203.0	COG0859@1|root,COG0859@2|Bacteria,2G8F3@200795|Chloroflexi,27Y39@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
MMS3_k127_2175912_2	479434.Sthe_1714	1.17e-127	419.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,27XSF@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2175912_6	479434.Sthe_1713	1.358e-94	322.0	COG0859@1|root,COG0859@2|Bacteria,2G6JB@200795|Chloroflexi,27XRD@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMS3_k127_2175912_5	479434.Sthe_1712	8.409e-96	326.0	COG0859@1|root,COG0859@2|Bacteria,2G8MX@200795|Chloroflexi,27Y5X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMS3_k127_2175912_7	479434.Sthe_1711	1.05e-70	241.0	COG0764@1|root,COG0764@2|Bacteria,2G8P4@200795|Chloroflexi,27YA6@189775|Thermomicrobia	189775|Thermomicrobia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
MMS3_k127_2175912_0	479434.Sthe_1710	1.019e-194	616.0	COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi,27XGV@189775|Thermomicrobia	189775|Thermomicrobia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
MMS3_k127_2175912_1	479434.Sthe_1709	1.536e-142	459.0	COG0484@1|root,COG0484@2|Bacteria,2G657@200795|Chloroflexi,27XSE@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C
MMS3_k127_2175912_9	479434.Sthe_1708	1.16e-44	170.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,27Z8D@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
MMS3_k127_2175912_3	479434.Sthe_1706	5.419e-117	389.0	COG0438@1|root,COG0438@2|Bacteria,2G713@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
MMS3_k127_2175912_4	479434.Sthe_1705	9.258e-104	341.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,27Y6E@189775|Thermomicrobia	189775|Thermomicrobia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
MMS3_k127_2175912_10	479434.Sthe_1704	8.522e-25	111.0	2A4SC@1|root,30TDT@2|Bacteria,2GBC2@200795|Chloroflexi,27YQR@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2175912_11	479434.Sthe_1703	5.805e-24	103.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi,27XIK@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
MMS3_k127_2184841_3	1445613.JALM01000130_gene6780	1.843e-48	186.0	COG2267@1|root,COG2267@2|Bacteria,2I3PK@201174|Actinobacteria,4EE6V@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_2184841_4	670292.JH26_10595	2.268e-15	81.0	2FKRB@1|root,34CBT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
MMS3_k127_2184841_1	1267535.KB906767_gene735	5.087e-93	314.0	COG1073@1|root,COG1073@2|Bacteria,3Y5TG@57723|Acidobacteria,2JNP5@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2184841_0	1267535.KB906767_gene735	1.846e-94	321.0	COG1073@1|root,COG1073@2|Bacteria,3Y5TG@57723|Acidobacteria,2JNP5@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2184841_2	479434.Sthe_1982	1.008e-87	296.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi,27Y9N@189775|Thermomicrobia	189775|Thermomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2186032_7	479434.Sthe_0690	2.005e-53	194.0	COG1670@1|root,COG1670@2|Bacteria,2G73Y@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_2186032_3	485913.Krac_9914	2.98e-147	479.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1,MFS_1_like
MMS3_k127_2186032_2	479434.Sthe_1630	3.313e-148	476.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16,5.3.1.8,5.3.1.9	ko:K00820,ko:K15916	ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931	M00001,M00004,M00114	R00768,R01819,R02739,R02740,R03321	RC00010,RC00163,RC00376,RC00563,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	SIS
MMS3_k127_2186032_1	247490.KSU1_A0073	3.817e-158	509.0	COG0479@1|root,COG0479@2|Bacteria,2IWTB@203682|Planctomycetes	203682|Planctomycetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
MMS3_k127_2186032_8	272134.KB731324_gene5861	3.83e-46	174.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_2186032_6	247490.KSU1_A0075	3.54e-105	349.0	COG0543@1|root,COG0543@2|Bacteria,2IYBB@203682|Planctomycetes	203682|Planctomycetes	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
MMS3_k127_2186032_5	322710.Avin_04390	3.189e-118	384.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Coenzyme F420-reducing hydrogenase, gamma subunit	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
MMS3_k127_2186032_0	247490.KSU1_A0077	2.603e-191	606.0	COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes	203682|Planctomycetes	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
MMS3_k127_2186032_9	272134.KB731324_gene5865	1.636e-25	111.0	COG0680@1|root,COG0680@2|Bacteria,1G5ZU@1117|Cyanobacteria,1HBCF@1150|Oscillatoriales	1117|Cyanobacteria	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
MMS3_k127_2186032_11	1122939.ATUD01000011_gene2206	2.355e-09	63.0	COG3246@1|root,COG3246@2|Bacteria,2GMMZ@201174|Actinobacteria,4CTHV@84995|Rubrobacteria	84995|Rubrobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
MMS3_k127_2186032_4	1157490.EL26_16860	3.164e-127	423.0	COG5476@1|root,COG5476@2|Bacteria,1UY0D@1239|Firmicutes,4HDB2@91061|Bacilli,279I8@186823|Alicyclobacillaceae	91061|Bacilli	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
MMS3_k127_2186032_10	1382356.JQMP01000004_gene503	1.566e-23	105.0	COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia	189775|Thermomicrobia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_2188315_3	525904.Tter_0136	4.776e-22	110.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
MMS3_k127_2188315_5	765869.BDW_00635	0.0003132	49.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2MSXJ@213481|Bdellovibrionales,2WIXN@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
MMS3_k127_2188315_2	118161.KB235919_gene6110	3.913e-22	108.0	COG0823@1|root,COG0823@2|Bacteria,1G8I3@1117|Cyanobacteria	1117|Cyanobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
MMS3_k127_2188315_1	485913.Krac_1545	3.143e-42	161.0	2DYI1@1|root,349VT@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_2188315_4	1218074.BAXZ01000006_gene1824	7.642e-17	93.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VK6G@28216|Betaproteobacteria,1K4GG@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
MMS3_k127_2188315_0	42256.RradSPS_1884	6.481e-88	304.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4CQ65@84995|Rubrobacteria	84995|Rubrobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2196783_9	1121272.KB903292_gene3994	2.314e-05	47.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4D952@85008|Micromonosporales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_2196783_7	656024.FsymDg_3098	9.38e-32	128.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_2196783_4	177439.DP2769	3.583e-78	282.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MHZK@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_2196783_1	926569.ANT_23280	1.213e-143	471.0	COG0520@1|root,COG0520@2|Bacteria,2G85X@200795|Chloroflexi	200795|Chloroflexi	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_2196783_3	926560.KE387023_gene3611	6.816e-87	304.0	COG0477@1|root,COG0477@2|Bacteria,1WNH1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2196783_8	383372.Rcas_0721	5.096e-16	81.0	COG0011@1|root,COG0011@2|Bacteria	2|Bacteria	H	TIGRFAM Protein of	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP,Ykof
MMS3_k127_2196783_6	419947.MRA_2019	1.237e-45	173.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2196783_5	485913.Krac_6314	1.097e-66	238.0	COG0491@1|root,COG0491@2|Bacteria,2G7MM@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
MMS3_k127_2196783_10	485913.Krac_8432	0.00055	46.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi	200795|Chloroflexi	V	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
MMS3_k127_2196783_0	485913.Krac_9117	5.052e-158	514.0	COG2986@1|root,COG2986@2|Bacteria,2G66R@200795|Chloroflexi	200795|Chloroflexi	E	PFAM phenylalanine histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
MMS3_k127_2196783_2	479434.Sthe_1107	5.153e-90	298.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi,27Z10@189775|Thermomicrobia	189775|Thermomicrobia	E	Urocanase C-terminal domain	-	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
MMS3_k127_2197381_3	479434.Sthe_1660	2.438e-118	391.0	COG1216@1|root,COG1216@2|Bacteria,2G66T@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_2197381_4	479434.Sthe_1659	1.048e-105	354.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,27XJM@189775|Thermomicrobia	189775|Thermomicrobia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
MMS3_k127_2197381_5	479434.Sthe_0255	5.057e-104	346.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	2|Bacteria	C	3-hydroxyacyl-CoA dehydrogenase domain protein	fadB3	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
MMS3_k127_2197381_7	479434.Sthe_1658	8.426e-26	109.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	spxA	-	1.20.4.1	ko:K00537,ko:K16509	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
MMS3_k127_2197381_2	479434.Sthe_1657	1.189e-130	421.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,27XEG@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
MMS3_k127_2197381_1	479434.Sthe_1653	1.414e-246	768.0	COG1012@1|root,COG1012@2|Bacteria,2G5NY@200795|Chloroflexi,27XK3@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
MMS3_k127_2197381_6	479434.Sthe_1652	9.882e-77	259.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi,27YAZ@189775|Thermomicrobia	189775|Thermomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
MMS3_k127_2197381_0	479434.Sthe_1651	0.0	1161.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi,27XUA@189775|Thermomicrobia	189775|Thermomicrobia	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
MMS3_k127_2199807_0	479434.Sthe_0359	4.969e-172	553.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,27XTS@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_2199807_1	360910.BAV1558	7.379e-85	299.0	COG1073@1|root,COG1073@2|Bacteria,1N0UG@1224|Proteobacteria,2VN4M@28216|Betaproteobacteria,3T33M@506|Alcaligenaceae	28216|Betaproteobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BAAT_C,Bile_Hydr_Trans
MMS3_k127_2199807_2	479434.Sthe_3115	8.172e-30	124.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2201211_4	479434.Sthe_0945	1.364e-54	194.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,27XUN@189775|Thermomicrobia	189775|Thermomicrobia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
MMS3_k127_2201211_0	479434.Sthe_0944	1.262e-272	857.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi,27XSG@189775|Thermomicrobia	189775|Thermomicrobia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
MMS3_k127_2201211_2	479434.Sthe_0943	1.707e-211	670.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi,27XK2@189775|Thermomicrobia	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
MMS3_k127_2201211_3	479434.Sthe_0942	2.662e-100	330.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi,27XM8@189775|Thermomicrobia	189775|Thermomicrobia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_2201211_1	479434.Sthe_0940	2.632e-251	792.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2G7WZ@200795|Chloroflexi,27XSW@189775|Thermomicrobia	189775|Thermomicrobia	L	GIY-YIG type nucleases (URI domain)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
MMS3_k127_220740_2	675635.Psed_0380	8.357e-102	344.0	COG0189@1|root,COG0189@2|Bacteria,2HUCI@201174|Actinobacteria,4E25P@85010|Pseudonocardiales	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_220740_1	675635.Psed_0380	1.042e-103	349.0	COG0189@1|root,COG0189@2|Bacteria,2HUCI@201174|Actinobacteria,4E25P@85010|Pseudonocardiales	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_220740_0	1122915.AUGY01000011_gene4004	2.099e-141	485.0	COG1132@1|root,COG1132@2|Bacteria,1TUQD@1239|Firmicutes,4HTPJ@91061|Bacilli,26U3G@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,cNMP_binding
MMS3_k127_2208788_0	1189612.A33Q_0629	0.0	1789.0	COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4PP4S@976|Bacteroidetes,47YN4@768503|Cytophagia	976|Bacteroidetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase
MMS3_k127_2208788_1	1189612.A33Q_0628	3.218e-153	507.0	COG0753@1|root,COG0753@2|Bacteria	2|Bacteria	C	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipoxygenase
MMS3_k127_2208788_4	1278073.MYSTI_02580	5.845e-31	128.0	COG0753@1|root,COG0753@2|Bacteria	2|Bacteria	C	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipoxygenase
MMS3_k127_2208788_2	1189612.A33Q_0627	2.576e-148	479.0	COG0753@1|root,COG0753@2|Bacteria	2|Bacteria	C	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2208788_3	1297865.APJD01000025_gene4013	6.952e-42	158.0	28P20@1|root,2ZBY6@2|Bacteria,1RBJ8@1224|Proteobacteria,2V61U@28211|Alphaproteobacteria,3K04Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2210025_0	479434.Sthe_3327	1.158e-95	344.0	COG2199@1|root,COG3903@1|root,COG3706@2|Bacteria,COG3903@2|Bacteria,2G64X@200795|Chloroflexi,27Z3R@189775|Thermomicrobia	189775|Thermomicrobia	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,GGDEF,NB-ARC,TPR_12
MMS3_k127_2210025_1	555088.DealDRAFT_0100	8.348e-43	174.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
MMS3_k127_2210025_2	1382306.JNIM01000001_gene4040	4.885e-28	122.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi	200795|Chloroflexi	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
MMS3_k127_2231884_4	479434.Sthe_1122	1.144e-29	118.0	COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi,27XYP@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
MMS3_k127_2231884_0	479434.Sthe_1123	1.857e-108	361.0	COG0451@1|root,COG0451@2|Bacteria,2GBGX@200795|Chloroflexi,27Y3C@189775|Thermomicrobia	189775|Thermomicrobia	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_2231884_3	1382356.JQMP01000001_gene973	2.811e-37	153.0	COG0223@1|root,COG0223@2|Bacteria,2G6VD@200795|Chloroflexi,27Z8I@189775|Thermomicrobia	189775|Thermomicrobia	J	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
MMS3_k127_2231884_2	479434.Sthe_1126	3.225e-48	174.0	COG2924@1|root,COG2924@2|Bacteria,2GA1Y@200795|Chloroflexi,27YKF@189775|Thermomicrobia	189775|Thermomicrobia	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
MMS3_k127_2231884_1	1382356.JQMP01000001_gene971	7.149e-99	327.0	COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi,27XHM@189775|Thermomicrobia	189775|Thermomicrobia	F	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
MMS3_k127_2238126_3	1499967.BAYZ01000152_gene1404	2.687e-150	482.0	COG2355@1|root,COG2355@2|Bacteria	2|Bacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMS3_k127_2238126_4	1341151.ASZU01000004_gene424	7.662e-34	146.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,27B6K@186824|Thermoactinomycetaceae	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_2238126_1	485913.Krac_9370	5.387e-234	739.0	COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi	2|Bacteria	P	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_2238126_0	485913.Krac_9369	4.024e-265	827.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_2238126_2	1476876.JOJO01000001_gene7783	1.11e-177	578.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria	201174|Actinobacteria	J	elongation factor G	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
MMS3_k127_2241193_0	525904.Tter_1475	4.502e-223	700.0	COG0366@1|root,COG0366@2|Bacteria,2NQFF@2323|unclassified Bacteria	2|Bacteria	G	Alpha-amylase domain	malL	-	3.2.1.10,3.2.1.20,3.2.1.93	ko:K01182,ko:K01187,ko:K01226	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
MMS3_k127_2241193_2	479434.Sthe_3374	9.596e-95	320.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi,27Y4W@189775|Thermomicrobia	200795|Chloroflexi	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMS3_k127_2241193_1	1382356.JQMP01000001_gene1281	1.016e-151	482.0	COG0160@1|root,COG0160@2|Bacteria,2G7XB@200795|Chloroflexi,27Z3E@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class-III	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_225355_6	479434.Sthe_0484	8.074e-43	160.0	COG3307@1|root,COG3307@2|Bacteria,2G6B1@200795|Chloroflexi,27XFU@189775|Thermomicrobia	189775|Thermomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_225355_8	479434.Sthe_0487	9.902e-29	120.0	COG1950@1|root,COG1950@2|Bacteria	2|Bacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2,Phosphodiest
MMS3_k127_225355_4	479434.Sthe_0488	1.055e-143	460.0	COG0329@1|root,COG0329@2|Bacteria,2G6U3@200795|Chloroflexi,27Y9D@189775|Thermomicrobia	200795|Chloroflexi	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	3.5.4.22	ko:K21062	ko00330,map00330	-	R02280	RC00679	ko00000,ko00001,ko01000	-	-	-	DHDPS
MMS3_k127_225355_7	1007103.AFHW01000026_gene425	1.71e-34	139.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,4HJ56@91061|Bacilli,26SDF@186822|Paenibacillaceae	91061|Bacilli	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
MMS3_k127_225355_3	479434.Sthe_0494	2.406e-145	469.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi,27Y2M@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_225355_1	479434.Sthe_0495	3.689e-229	717.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,27XFV@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
MMS3_k127_225355_0	479434.Sthe_0496	0.0	1460.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi,27XGF@189775|Thermomicrobia	189775|Thermomicrobia	O	Sigma-54 interaction domain	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
MMS3_k127_225355_2	479434.Sthe_0497	9.552e-194	613.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi,27XMK@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ChlI
MMS3_k127_225355_5	479434.Sthe_0498	9.49e-57	203.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi,27YX8@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
MMS3_k127_2260274_3	479434.Sthe_2350	1.847e-80	299.0	COG0823@1|root,COG0823@2|Bacteria,2GBFZ@200795|Chloroflexi,27ZCM@189775|Thermomicrobia	189775|Thermomicrobia	U	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2260274_4	1038859.AXAU01000017_gene6274	1.547e-73	253.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,3JRSQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_3
MMS3_k127_2260274_9	555088.DealDRAFT_1205	1.992e-05	49.0	2EUZT@1|root,33NF0@2|Bacteria,1VK80@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2260274_5	479434.Sthe_1375	2.613e-33	136.0	COG0640@1|root,COG0640@2|Bacteria,2G7FZ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
MMS3_k127_2260274_0	1379270.AUXF01000002_gene1104	5.8e-184	595.0	COG0003@1|root,COG0003@2|Bacteria,1ZVAB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
MMS3_k127_2260274_6	90814.KL370892_gene2089	3.409e-26	115.0	COG1765@1|root,COG1765@2|Bacteria,1RIBQ@1224|Proteobacteria,1S871@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS3_k127_2260274_1	479434.Sthe_1374	2.804e-169	538.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
MMS3_k127_2260274_8	383372.Rcas_2315	9.192e-09	57.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2G6GF@200795|Chloroflexi,377ZH@32061|Chloroflexia	32061|Chloroflexia	K	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
MMS3_k127_2260274_2	479434.Sthe_1371	9.951e-114	370.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_2260274_7	196162.Noca_4966	4.962e-13	72.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_2278230_1	479434.Sthe_2690	6.831e-36	138.0	COG0296@1|root,COG0296@2|Bacteria,2G9SJ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
MMS3_k127_2278230_0	479434.Sthe_3301	2.968e-190	600.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,27YZQ@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_2278230_2	1136417.AZWE01000005_gene4643	2.374e-07	61.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4D96C@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
MMS3_k127_2278230_3	1121377.KB906402_gene3226	0.0001958	47.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,DUF4062,GerE,TPR_12
MMS3_k127_2279589_0	479434.Sthe_2748	6.406e-155	509.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	2|Bacteria	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_2279589_3	479434.Sthe_3282	2.251e-52	199.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMS3_k127_2279589_2	479434.Sthe_3282	1.132e-57	217.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMS3_k127_2279589_1	1382356.JQMP01000001_gene1056	9.023e-136	436.0	COG0726@1|root,COG0726@2|Bacteria,2GB8A@200795|Chloroflexi,27XZW@189775|Thermomicrobia	189775|Thermomicrobia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_2283208_0	1394178.AWOO02000003_gene2762	3.836e-307	947.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4EFUP@85012|Streptosporangiales	201174|Actinobacteria	L	ABC transporter	uvrA2	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_2283208_6	1380347.JNII01000006_gene1616	8.127e-53	197.0	2E39M@1|root,32Y96@2|Bacteria,2IITE@201174|Actinobacteria,4EW7J@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2283208_12	525904.Tter_1488	4.404e-09	60.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_2283208_5	304371.MCP_0427	2.438e-59	216.0	arCOG07533@1|root,arCOG07533@2157|Archaea	304371.MCP_0427|-	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2283208_13	1304275.C41B8_16594	0.000404	47.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K05548	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,Sugar_tr
MMS3_k127_2283208_1	710696.Intca_2891	2.124e-153	510.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4FFEC@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_2283208_10	219305.MCAG_05171	5.581e-32	130.0	COG4275@1|root,COG4275@2|Bacteria,2IK0B@201174|Actinobacteria,4DIR5@85008|Micromonosporales	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
MMS3_k127_2283208_11	1120950.KB892800_gene1657	6.176e-30	125.0	COG4275@1|root,COG4275@2|Bacteria,2IJYK@201174|Actinobacteria	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2283208_4	596154.Alide2_1935	5.443e-67	239.0	COG3173@1|root,COG3173@2|Bacteria,1NRUX@1224|Proteobacteria,2VZIY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_2283208_9	610130.Closa_2827	4.72e-47	184.0	COG1131@1|root,COG1131@2|Bacteria,1UHTY@1239|Firmicutes,24JZH@186801|Clostridia,220CE@1506553|Lachnoclostridium	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2283208_2	610130.Closa_2826	7.658e-78	272.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_2283208_3	610130.Closa_2825	1.685e-71	256.0	COG1131@1|root,COG1131@2|Bacteria,1UHTY@1239|Firmicutes,24JZH@186801|Clostridia,22450@1506553|Lachnoclostridium	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2283208_8	610130.Closa_2824	2.294e-49	189.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_2286442_4	309801.trd_1809	3.249e-49	181.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_2286442_1	479434.Sthe_0908	1.345e-111	369.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi,27Y9N@189775|Thermomicrobia	189775|Thermomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2286442_5	479434.Sthe_0909	4.938e-31	134.0	2BHS8@1|root,33DMI@2|Bacteria,2GBGN@200795|Chloroflexi,27YQG@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
MMS3_k127_2286442_0	1343740.M271_06895	6.704e-117	382.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2286442_3	1038866.KB902769_gene1493	2.69e-58	207.0	COG2128@1|root,COG2128@2|Bacteria,1RIKK@1224|Proteobacteria,2U9KG@28211|Alphaproteobacteria,3JX3V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	MA20_06775	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_2286442_6	485913.Krac_0527	8.727e-29	126.0	COG2259@1|root,31BQE@2|Bacteria	2|Bacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
MMS3_k127_2286442_2	287986.DV20_31585	9.22e-65	234.0	COG1305@1|root,COG1305@2|Bacteria,2GKPF@201174|Actinobacteria,4E9XD@85010|Pseudonocardiales	201174|Actinobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
MMS3_k127_2286442_7	867845.KI911784_gene1050	2.286e-19	94.0	2CMS6@1|root,32SFE@2|Bacteria,2G905@200795|Chloroflexi,377IA@32061|Chloroflexia	32061|Chloroflexia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_2292244_5	479434.Sthe_3476	2.485e-38	145.0	COG0022@1|root,COG0022@2|Bacteria,2GAAM@200795|Chloroflexi,27YTG@189775|Thermomicrobia	189775|Thermomicrobia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMS3_k127_2292244_1	1408254.T458_02180	7.046e-117	392.0	COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,26SPG@186822|Paenibacillaceae	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bkdB	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_2292244_9	42256.RradSPS_0535	6.92e-27	114.0	COG1226@1|root,COG1226@2|Bacteria,2H11C@201174|Actinobacteria,4CTJD@84995|Rubrobacteria	84995|Rubrobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
MMS3_k127_2292244_2	479434.Sthe_0079	2.878e-99	334.0	COG1387@1|root,COG1387@2|Bacteria,2G8ST@200795|Chloroflexi,27ZB2@189775|Thermomicrobia	189775|Thermomicrobia	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
MMS3_k127_2292244_0	526227.Mesil_0165	1.152e-140	456.0	COG0446@1|root,COG0446@2|Bacteria,1WI8N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	FAD-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_2292244_8	326427.Cagg_3436	9.565e-33	128.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	-	-	-	-	-	-	-	-	-	-	TusA
MMS3_k127_2292244_4	1156937.MFUM_550026	1.128e-39	152.0	COG2210@1|root,COG2210@2|Bacteria,46ZAV@74201|Verrucomicrobia,37GMZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
MMS3_k127_2292244_3	479434.Sthe_2559	5.702e-80	278.0	COG1376@1|root,COG1376@2|Bacteria,2G8JH@200795|Chloroflexi,27XUR@189775|Thermomicrobia	2|Bacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2778,PG_binding_1,YkuD
MMS3_k127_2292244_7	929556.Solca_0685	1.962e-36	141.0	COG0681@1|root,COG0681@2|Bacteria,4NSIR@976|Bacteroidetes,1ITMV@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2292244_6	298654.FraEuI1c_3191	6.319e-37	150.0	COG0640@1|root,COG0640@2|Bacteria,2IQ06@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_2294013_3	316274.Haur_3068	4.596e-58	211.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	2|Bacteria	KLT	SMART tyrosine protein kinase	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
MMS3_k127_2294013_1	309801.trd_0945	4.757e-159	516.0	COG1488@1|root,COG1488@2|Bacteria,2GAK8@200795|Chloroflexi,27YGV@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
MMS3_k127_2294013_6	1382356.JQMP01000003_gene2298	3.23e-32	130.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,27YH5@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_2294013_5	479434.Sthe_1075	4.04e-38	147.0	COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi,27ZAC@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
MMS3_k127_2294013_0	357808.RoseRS_1575	8.016e-175	562.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
MMS3_k127_2294013_2	479434.Sthe_1073	8.157e-68	237.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_2294013_4	479434.Sthe_1072	9.305e-54	197.0	COG0406@1|root,COG0406@2|Bacteria,2G726@200795|Chloroflexi,27Z7X@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
MMS3_k127_2297438_7	324925.Ppha_2599	1.793e-11	67.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4
MMS3_k127_2297438_3	1267535.KB906767_gene4067	6.719e-85	293.0	COG0668@1|root,COG0668@2|Bacteria,3Y375@57723|Acidobacteria,2JHWN@204432|Acidobacteriia	204432|Acidobacteriia	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
MMS3_k127_2297438_6	28564.XP_002477883.1	4.269e-14	81.0	KOG1218@1|root,KOG1218@2759|Eukaryota	2759|Eukaryota	S	negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	-	-	-	-	-	-	-	-	-	-	-	-	EB,TIL
MMS3_k127_2297438_0	479434.Sthe_2726	2.388e-263	817.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
MMS3_k127_2297438_2	309801.trd_A0730	5.705e-96	341.0	COG1525@1|root,COG1525@2|Bacteria,2GBHE@200795|Chloroflexi,27YTT@189775|Thermomicrobia	189775|Thermomicrobia	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2297438_5	1223410.KN050846_gene73	2.802e-21	98.0	2EKX6@1|root,33EKQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2297438_4	485913.Krac_5908	1.772e-61	216.0	COG0778@1|root,COG0778@2|Bacteria,2G7DQ@200795|Chloroflexi	200795|Chloroflexi	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_2297438_1	1382356.JQMP01000001_gene965	1.419e-112	368.0	COG0684@1|root,COG0684@2|Bacteria,2GB46@200795|Chloroflexi,27YTB@189775|Thermomicrobia	189775|Thermomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
MMS3_k127_2299147_5	479434.Sthe_2872	2.321e-93	311.0	COG0624@1|root,COG0624@2|Bacteria,2G60R@200795|Chloroflexi,27Y02@189775|Thermomicrobia	2|Bacteria	E	peptidase dimerisation domain protein	cpg2	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_2299147_10	383372.Rcas_2233	1.565e-33	136.0	COG4552@1|root,COG4552@2|Bacteria,2GAIZ@200795|Chloroflexi,376FX@32061|Chloroflexia	32061|Chloroflexia	S	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
MMS3_k127_2299147_9	1123237.Salmuc_03667	6.112e-56	207.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2U391@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_2299147_1	479434.Sthe_2594	2.351e-199	627.0	COG0297@1|root,COG0297@2|Bacteria,2G88Y@200795|Chloroflexi,27XIV@189775|Thermomicrobia	189775|Thermomicrobia	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2299147_3	479434.Sthe_3140	9.179e-140	467.0	COG3568@1|root,COG3568@2|Bacteria,2G7ER@200795|Chloroflexi,27XU2@189775|Thermomicrobia	189775|Thermomicrobia	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
MMS3_k127_2299147_7	479434.Sthe_3115	3.855e-75	264.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2299147_6	1123023.JIAI01000006_gene342	2.734e-88	305.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C,M20_dimer,Peptidase_M20
MMS3_k127_2299147_4	1382356.JQMP01000003_gene1376	1.309e-135	439.0	COG1363@1|root,COG1363@2|Bacteria,2GB54@200795|Chloroflexi,27YYZ@189775|Thermomicrobia	189775|Thermomicrobia	E	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
MMS3_k127_2299147_0	266117.Rxyl_2051	1.632e-268	861.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	2|Bacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
MMS3_k127_2299147_11	398512.JQKC01000001_gene2145	4.59e-19	95.0	2A4HR@1|root,30T4A@2|Bacteria,1V3W0@1239|Firmicutes,24I5I@186801|Clostridia,3WJ3D@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2299147_2	479434.Sthe_2106	4.978e-143	466.0	COG0438@1|root,COG0438@2|Bacteria,2G8D2@200795|Chloroflexi,27YUH@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
MMS3_k127_2299147_8	497964.CfE428DRAFT_3417	1.336e-63	226.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2299147_13	1382356.JQMP01000003_gene1984	2.624e-10	66.0	COG1826@1|root,COG1826@2|Bacteria,2GBFR@200795|Chloroflexi,27ZC2@189775|Thermomicrobia	189775|Thermomicrobia	U	mttA/Hcf106 family	-	-	-	-	-	-	-	-	-	-	-	-	MttA_Hcf106
MMS3_k127_2299147_12	694431.DESACE_04790	1.592e-17	88.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,42PR8@68525|delta/epsilon subdivisions,2WK8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2299984_6	555079.Toce_1513	2.18e-45	177.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia,42F00@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMS3_k127_2299984_3	479434.Sthe_3071	1.013e-91	311.0	COG2141@1|root,COG2141@2|Bacteria,2G8CA@200795|Chloroflexi,27Y7R@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2299984_9	1211115.ALIQ01000190_gene923	2.591e-28	120.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL,SnoaL_2
MMS3_k127_2299984_0	285514.JNWO01000004_gene6157	7.034e-236	751.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_2299984_8	1380390.JIAT01000016_gene5480	4.711e-33	136.0	COG1309@1|root,COG1309@2|Bacteria,2HQAH@201174|Actinobacteria,4CRUK@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2299984_5	526227.Mesil_0655	5.714e-70	241.0	COG1670@1|root,COG1670@2|Bacteria,1WKMY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_2299984_1	479434.Sthe_1454	9.298e-112	373.0	COG0715@1|root,COG0715@2|Bacteria,2G71V@200795|Chloroflexi,27YNK@189775|Thermomicrobia	189775|Thermomicrobia	P	NMT1-like family	-	-	-	ko:K02051,ko:K15598	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	NMT1
MMS3_k127_2299984_2	479434.Sthe_1453	7.617e-101	336.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi,27YDK@189775|Thermomicrobia	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
MMS3_k127_2299984_7	1123023.JIAI01000007_gene1829	1.104e-37	147.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	pdxH	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
MMS3_k127_2299984_4	63737.Npun_R1621	1.93e-83	289.0	COG3511@1|root,COG3511@2|Bacteria,1GA7F@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
MMS3_k127_230438_2	1123392.AQWL01000004_gene2603	1.144e-48	180.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2VQ9J@28216|Betaproteobacteria,1KSDQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
MMS3_k127_230438_3	1461577.CCMH01000004_gene1164	4.235e-07	60.0	COG0500@1|root,COG0537@1|root,COG0500@2|Bacteria,COG0537@2|Bacteria,4NEYS@976|Bacteroidetes,1I3RF@117743|Flavobacteriia	976|Bacteroidetes	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	-	-	-	-	-	-	-	-	-	HIT,Methyltransf_23
MMS3_k127_230438_1	1173024.KI912152_gene716	8.756e-109	370.0	2CCB0@1|root,2Z8JN@2|Bacteria,1GDKA@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NurA
MMS3_k127_230438_0	1173024.KI912152_gene715	3.345e-236	746.0	COG0433@1|root,COG0433@2|Bacteria,1GE18@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
MMS3_k127_2311665_2	1158050.KB895455_gene1714	4.208e-121	395.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria	201174|Actinobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMS3_k127_2311665_0	330214.NIDE3851	2.742e-278	869.0	COG0365@1|root,COG0365@2|Bacteria,3J0BJ@40117|Nitrospirae	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS3_k127_2311665_3	1382306.JNIM01000001_gene564	5.001e-26	119.0	COG2091@1|root,COG2091@2|Bacteria,2G8SS@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
MMS3_k127_2311665_1	479434.Sthe_0227	5.182e-187	590.0	COG0587@1|root,COG0587@2|Bacteria,2G811@200795|Chloroflexi,27Z3J@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
MMS3_k127_2316648_0	319003.Bra1253DRAFT_07272	5.136e-259	803.0	COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,2TTWJ@28211|Alphaproteobacteria,3JUQG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Dimer_Tnp_Tn5,Tnp_DNA_bind
MMS3_k127_2316648_4	1038858.AXBA01000075_gene4092	6.179e-05	45.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2UBQE@28211|Alphaproteobacteria,3EZMA@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
MMS3_k127_2316648_1	266835.14025834	3.887e-133	430.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,43MYQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve_3
MMS3_k127_2316648_3	1232410.KI421421_gene3245	1.099e-22	101.0	COG0437@1|root,COG0437@2|Bacteria,1NF8S@1224|Proteobacteria,42WBD@68525|delta/epsilon subdivisions,2WRT3@28221|Deltaproteobacteria,43VH5@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
MMS3_k127_2316648_2	1232410.KI421421_gene3246	4.118e-120	396.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,43TBB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMS3_k127_2320278_1	196162.Noca_4966	1.465e-123	422.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_2320278_2	1382306.JNIM01000001_gene706	2.12e-123	409.0	COG4102@1|root,COG4102@2|Bacteria,2G79B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
MMS3_k127_2320278_0	1382356.JQMP01000004_gene511	1.008e-160	521.0	COG5267@1|root,COG5267@2|Bacteria,2G6X1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
MMS3_k127_2322566_0	479434.Sthe_0018	1e-100	339.0	2AS16@1|root,31HDI@2|Bacteria,2GA0F@200795|Chloroflexi,27YBE@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2322566_6	479434.Sthe_0015	1.931e-60	213.0	COG0454@1|root,COG0456@2|Bacteria,2GBA6@200795|Chloroflexi,27YFS@189775|Thermomicrobia	189775|Thermomicrobia	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
MMS3_k127_2322566_5	479434.Sthe_0681	7.021e-66	233.0	COG2186@1|root,COG2186@2|Bacteria,2GBBV@200795|Chloroflexi,27YQ1@189775|Thermomicrobia	189775|Thermomicrobia	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
MMS3_k127_2322566_4	1382356.JQMP01000004_gene503	6.772e-66	242.0	COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia	189775|Thermomicrobia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_2322566_1	36080.S2JBH8	8.951e-95	321.0	28M44@1|root,2QTM1@2759|Eukaryota,39THH@33154|Opisthokonta,3NXIA@4751|Fungi,1GVUJ@112252|Fungi incertae sedis	4751|Fungi	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMS3_k127_2322566_7	479434.Sthe_2139	5.742e-52	189.0	2BQKR@1|root,32JGS@2|Bacteria,2GA1C@200795|Chloroflexi,27YM2@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2322566_2	479434.Sthe_2142	3.911e-93	312.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi,27XIR@189775|Thermomicrobia	189775|Thermomicrobia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
MMS3_k127_2322566_3	1035308.AQYY01000001_gene2445	4.646e-70	251.0	COG1226@1|root,COG1226@2|Bacteria,1V2CY@1239|Firmicutes,24DT6@186801|Clostridia,260Z7@186807|Peptococcaceae	186801|Clostridia	P	PFAM TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
MMS3_k127_2322566_8	479434.Sthe_2143	1.945e-18	94.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
MMS3_k127_2323944_0	518766.Rmar_1581	1.481e-146	475.0	COG0076@1|root,COG0076@2|Bacteria,4NGRW@976|Bacteroidetes,1FJ4Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
MMS3_k127_23288_3	1229780.BN381_130166	5.328e-59	211.0	2DCZU@1|root,2ZFYS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_23288_2	485913.Krac_2581	2.342e-91	314.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
MMS3_k127_23288_0	479434.Sthe_3008	2.706e-162	536.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2G8KM@200795|Chloroflexi,27XZB@189775|Thermomicrobia	200795|Chloroflexi	P	Copper resistance protein CopC	-	-	-	-	-	-	-	-	-	-	-	-	CopC,CopD
MMS3_k127_23288_1	479434.Sthe_2790	4.784e-147	476.0	COG0477@1|root,COG0477@2|Bacteria,2G5YG@200795|Chloroflexi,27XKV@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_23288_4	1097668.BYI23_B008530	9.444e-20	90.0	COG4101@1|root,COG4101@2|Bacteria,1RIHD@1224|Proteobacteria,2VT14@28216|Betaproteobacteria,1K7BE@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_2329026_1	479434.Sthe_2068	1.856e-118	386.0	COG2141@1|root,COG2141@2|Bacteria,2G8NG@200795|Chloroflexi,27Y54@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2329026_0	316274.Haur_4945	4.401e-164	534.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	2|Bacteria	S	PFAM ABC transporter related	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
MMS3_k127_2329706_0	479434.Sthe_1092	0.0	1131.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
MMS3_k127_2329706_1	472759.Nhal_2490	2.671e-273	856.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1WX35@135613|Chromatiales	135613|Chromatiales	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
MMS3_k127_2329706_2	926549.KI421517_gene4006	2.514e-07	55.0	COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,47KIY@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.41,3.2.1.68	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
MMS3_k127_2330511_2	1499967.BAYZ01000020_gene5225	8.639e-42	158.0	COG5001@1|root,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
MMS3_k127_2330511_1	479434.Sthe_2605	5.675e-60	217.0	COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi,27Z4D@189775|Thermomicrobia	189775|Thermomicrobia	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
MMS3_k127_2330511_0	926560.KE387023_gene2049	3.04e-160	529.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
MMS3_k127_2333709_1	479434.Sthe_2350	4.791e-74	280.0	COG0823@1|root,COG0823@2|Bacteria,2GBFZ@200795|Chloroflexi,27ZCM@189775|Thermomicrobia	189775|Thermomicrobia	U	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2333709_2	1121918.ARWE01000001_gene3041	4.941e-22	98.0	COG2010@1|root,COG2010@2|Bacteria,1NKKK@1224|Proteobacteria,42UAC@68525|delta/epsilon subdivisions,2WXVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
MMS3_k127_2333709_3	671143.DAMO_0589	0.0002031	44.0	COG2010@1|root,COG2010@2|Bacteria,2NR69@2323|unclassified Bacteria	2|Bacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
MMS3_k127_2333709_0	479434.Sthe_2343	2.41e-104	355.0	COG0477@1|root,COG2814@2|Bacteria,2G9NF@200795|Chloroflexi,27Y14@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_233961_4	479434.Sthe_1345	1.654e-40	150.0	COG3693@1|root,COG3693@2|Bacteria,2GBGU@200795|Chloroflexi,27XYU@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
MMS3_k127_233961_1	479434.Sthe_1344	7.171e-131	426.0	COG0309@1|root,COG0309@2|Bacteria,2G8E4@200795|Chloroflexi,27XEQ@189775|Thermomicrobia	189775|Thermomicrobia	O	AIR synthase related protein, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
MMS3_k127_233961_2	309801.trd_0608	7.969e-131	429.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,27XQ7@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
MMS3_k127_233961_0	479434.Sthe_1342	2.406e-255	795.0	COG0442@1|root,COG0442@2|Bacteria,2G636@200795|Chloroflexi,27XHT@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
MMS3_k127_233961_5	1370121.AUWS01000058_gene3663	6.14e-12	72.0	2F2AI@1|root,33V8H@2|Bacteria,2IGXD@201174|Actinobacteria,238TK@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_233961_3	1382356.JQMP01000003_gene1829	5.346e-96	335.0	COG1840@1|root,COG1840@2|Bacteria,2GBNE@200795|Chloroflexi,27ZCW@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_233961_6	479433.Caci_0954	0.0002217	52.0	2EN0B@1|root,33FNI@2|Bacteria,2GZRB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2349413_5	526227.Mesil_3471	3.797e-47	175.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_2349413_0	479434.Sthe_1797	4.357e-178	564.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi,27XSK@189775|Thermomicrobia	200795|Chloroflexi	E	PFAM alanine racemase domain protein	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
MMS3_k127_2349413_3	1283283.ATXA01000008_gene2989	7.089e-73	257.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2349413_1	479434.Sthe_1795	1.03e-132	430.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi,27XVJ@189775|Thermomicrobia	189775|Thermomicrobia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMS3_k127_2349413_2	1120950.KB892826_gene652	7.094e-124	405.0	COG0500@1|root,COG2226@2|Bacteria,2GRM0@201174|Actinobacteria,4DRX2@85009|Propionibacteriales	201174|Actinobacteria	Q	O-methyltransferase	-	-	2.1.1.303,2.1.1.343,2.3.1.235	ko:K15886,ko:K16034,ko:K20421,ko:K22269	ko01051,ko01052,ko01056,ko01057,ko01059,ko01130,map01051,map01052,map01056,map01057,map01059,map01130	M00778,M00783,M00830	R06701,R09269,R09852,R10960,R10963	RC00003,RC00392,RC02496	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimerisation2,Methyltransf_2
MMS3_k127_2349413_4	1303518.CCALI_00715	2.241e-70	249.0	COG1230@1|root,COG1230@2|Bacteria	2|Bacteria	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
MMS3_k127_2349413_7	479434.Sthe_3141	2.802e-27	115.0	2AU22@1|root,31JN8@2|Bacteria,2GA5W@200795|Chloroflexi,27ZCB@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2349413_6	479434.Sthe_3010	1.428e-37	145.0	COG0640@1|root,COG0640@2|Bacteria,2G78R@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
MMS3_k127_2349413_8	479434.Sthe_3009	2.26e-26	111.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,2G5QF@200795|Chloroflexi	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
MMS3_k127_235131_6	479434.Sthe_0804	3.892e-30	124.0	COG3807@1|root,COG3807@2|Bacteria,2GBAP@200795|Chloroflexi,27YJC@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
MMS3_k127_235131_3	479434.Sthe_0803	6.759e-153	490.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi,27XQX@189775|Thermomicrobia	189775|Thermomicrobia	C	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
MMS3_k127_235131_5	479434.Sthe_0802	8.646e-58	208.0	2F2ZT@1|root,33VV3@2|Bacteria,2GB9U@200795|Chloroflexi,27YE4@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_235131_2	479434.Sthe_0801	1.368e-154	497.0	COG0476@1|root,COG0476@2|Bacteria,2G5Q1@200795|Chloroflexi,27XM2@189775|Thermomicrobia	189775|Thermomicrobia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
MMS3_k127_235131_1	479434.Sthe_0800	6.232e-183	579.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi,27XIH@189775|Thermomicrobia	189775|Thermomicrobia	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_235131_7	479434.Sthe_0799	1.718e-27	117.0	2A4SD@1|root,30TDU@2|Bacteria,2GA25@200795|Chloroflexi,27YQS@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_235131_4	479434.Sthe_0798	7.822e-73	248.0	COG0494@1|root,COG0494@2|Bacteria,2GB9J@200795|Chloroflexi,27YBS@189775|Thermomicrobia	189775|Thermomicrobia	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
MMS3_k127_235131_0	479434.Sthe_0796	0.0	1117.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
MMS3_k127_235131_8	479434.Sthe_0795	1.363e-19	94.0	2BQJQ@1|root,32JFR@2|Bacteria,2GA0E@200795|Chloroflexi,27YBB@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2355545_1	717605.Theco_3327	6.19e-72	258.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,4HDVV@91061|Bacilli,26TT1@186822|Paenibacillaceae	91061|Bacilli	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
MMS3_k127_2355545_2	448385.sce8089	6.884e-41	159.0	2BZKP@1|root,337K0@2|Bacteria,1N9R0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2355545_0	706587.Desti_1932	8.009e-234	736.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6	ko:K01535,ko:K12955	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.24,3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMS3_k127_2358190_9	485913.Krac_2627	0.0001175	47.0	28XV3@1|root,2ZJRF@2|Bacteria	2|Bacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
MMS3_k127_2358190_4	485913.Krac_4988	1.396e-138	448.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
MMS3_k127_2358190_5	479434.Sthe_3334	1.368e-113	375.0	COG2084@1|root,COG2084@2|Bacteria,2G6B3@200795|Chloroflexi,27YBY@189775|Thermomicrobia	189775|Thermomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_2358190_6	479434.Sthe_3333	2.267e-104	345.0	COG2188@1|root,COG2188@2|Bacteria,2GBGB@200795|Chloroflexi,27Z9U@189775|Thermomicrobia	189775|Thermomicrobia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
MMS3_k127_2358190_0	479434.Sthe_3332	4.621e-180	571.0	COG0520@1|root,COG0520@2|Bacteria,2G7ZH@200795|Chloroflexi,27Z06@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_2358190_2	479434.Sthe_3330	1.741e-166	530.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi,27Y0M@189775|Thermomicrobia	189775|Thermomicrobia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
MMS3_k127_2358190_3	479434.Sthe_3329	6.559e-160	524.0	COG3391@1|root,COG3391@2|Bacteria,2GA2S@200795|Chloroflexi,27YI0@189775|Thermomicrobia	189775|Thermomicrobia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2358190_1	479434.Sthe_3328	1.867e-168	534.0	COG0407@1|root,COG0407@2|Bacteria,2G7RT@200795|Chloroflexi,27XN9@189775|Thermomicrobia	189775|Thermomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
MMS3_k127_2358190_8	926550.CLDAP_25240	8.022e-12	70.0	COG1547@1|root,COG3437@1|root,COG1547@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309,HD
MMS3_k127_2358190_7	479434.Sthe_3326	4.91e-61	211.0	COG4974@1|root,COG4974@2|Bacteria,2G94T@200795|Chloroflexi,27XHI@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_2362525_3	479434.Sthe_2531	3.442e-82	280.0	2CYFR@1|root,32T44@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
MMS3_k127_2362525_4	479434.Sthe_2947	3.704e-47	176.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi	200795|Chloroflexi	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
MMS3_k127_2362525_6	1382356.JQMP01000004_gene91	3.396e-36	142.0	COG3304@1|root,COG3304@2|Bacteria,2G74I@200795|Chloroflexi	200795|Chloroflexi	S	Inner membrane component domain	-	-	-	-	-	-	-	-	-	-	-	-	YccF
MMS3_k127_2362525_1	192952.MM_3157	2.136e-115	390.0	COG1680@1|root,arCOG00771@2157|Archaea	2157|Archaea	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A1202	Beta-lactamase
MMS3_k127_2362525_5	797209.ZOD2009_10355	4.395e-46	175.0	arCOG13341@1|root,arCOG13341@2157|Archaea,2XXWE@28890|Euryarchaeota,23WKG@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2362525_7	158500.BV97_00066	5.33e-10	64.0	COG0457@1|root,COG0457@2|Bacteria,1RCR5@1224|Proteobacteria,2VG5D@28211|Alphaproteobacteria,2K8JD@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF4236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236
MMS3_k127_2362525_0	479434.Sthe_3375	9.972e-144	469.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi,27YUW@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_2362525_2	309801.trd_A0362	5.622e-90	300.0	COG0160@1|root,COG0160@2|Bacteria,2G7XB@200795|Chloroflexi,27Z3E@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class-III	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_2378244_4	1123229.AUBC01000025_gene4509	0.0003204	50.0	2B7JE@1|root,320Q3@2|Bacteria,1MYMM@1224|Proteobacteria,2U977@28211|Alphaproteobacteria,3K5PH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
MMS3_k127_2378244_3	1370125.AUWT01000082_gene3824	4.547e-13	74.0	2AF64@1|root,3154Z@2|Bacteria,2IKGJ@201174|Actinobacteria,239B3@1762|Mycobacteriaceae	201174|Actinobacteria	K	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
MMS3_k127_2378244_1	485913.Krac_4868	8.666e-49	179.0	2CMS6@1|root,32SFE@2|Bacteria,2G905@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_2378244_0	1449976.KALB_3921	3.033e-129	422.0	COG1831@1|root,COG1831@2|Bacteria,2GM9F@201174|Actinobacteria,4DZYC@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2378244_2	485913.Krac_4868	3.44e-23	102.0	2CMS6@1|root,32SFE@2|Bacteria,2G905@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_2379959_2	745776.DGo_CA1915	5.322e-82	276.0	COG0435@1|root,COG0435@2|Bacteria	2|Bacteria	O	Glutathione S-transferase	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7,2.5.1.18	ko:K00799,ko:K07393	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	iECW_1372.ECW_m3373,iWFL_1372.ECW_m3373	GST_C_2,GST_N_2
MMS3_k127_2379959_3	396588.Tgr7_0811	1.031e-19	91.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1WWS1@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
MMS3_k127_2379959_1	479434.Sthe_2653	1.947e-97	325.0	COG0682@1|root,COG0682@2|Bacteria,2G78M@200795|Chloroflexi,27XSN@189775|Thermomicrobia	189775|Thermomicrobia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
MMS3_k127_2379959_0	479434.Sthe_2148	7.962e-104	348.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi,27XPC@189775|Thermomicrobia	189775|Thermomicrobia	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
MMS3_k127_2382402_2	1122221.JHVI01000008_gene2349	2.763e-21	97.0	COG1943@1|root,COG1943@2|Bacteria,1WMVN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2382402_0	479434.Sthe_0130	1.244e-176	561.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi	200795|Chloroflexi	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_2382402_1	1234664.AMRO01000075_gene2783	2.133e-69	247.0	COG0111@1|root,COG0111@2|Bacteria,1TQ7W@1239|Firmicutes,4HDEC@91061|Bacilli,1WG92@129337|Geobacillus	91061|Bacilli	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_2400113_1	309801.trd_1335	5.056e-83	291.0	COG0730@1|root,COG0730@2|Bacteria,2G6ZH@200795|Chloroflexi,27YU2@189775|Thermomicrobia	189775|Thermomicrobia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_2400113_0	469383.Cwoe_4241	1.298e-134	458.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4CRVY@84995|Rubrobacteria	84995|Rubrobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_2400113_4	357808.RoseRS_1669	3.19e-23	103.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria,2G805@200795|Chloroflexi	200795|Chloroflexi	T	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
MMS3_k127_2400113_2	357808.RoseRS_1669	4.115e-44	164.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria,2G805@200795|Chloroflexi	200795|Chloroflexi	T	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
MMS3_k127_2400113_3	383372.Rcas_2809	2.359e-26	121.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
MMS3_k127_2400113_6	340177.Cag_1910	1.754e-18	91.0	COG0823@1|root,COG0823@2|Bacteria,1FEIQ@1090|Chlorobi	1090|Chlorobi	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
MMS3_k127_2400113_5	1239962.C943_03877	1.575e-22	101.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
MMS3_k127_2400113_7	1382356.JQMP01000003_gene1512	4.83e-15	76.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	rutC	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
MMS3_k127_2417886_1	479434.Sthe_1462	3.041e-50	181.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi,27Y2G@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_2417886_5	483219.LILAB_30150	3.056e-09	60.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2Z0TJ@29|Myxococcales	28221|Deltaproteobacteria	P	arsenical-resistance protein	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
MMS3_k127_2417886_6	1009370.ALO_18020	0.0001643	45.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,4H2KS@909932|Negativicutes	909932|Negativicutes	P	arsenical-resistance protein	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
MMS3_k127_2417886_3	3885.XP_007149125.1	1.951e-24	116.0	28IF1@1|root,2QQRS@2759|Eukaryota,37NSV@33090|Viridiplantae,3GFZY@35493|Streptophyta,4JEVW@91835|fabids	35493|Streptophyta	S	Vacuolar protein sorting-associated protein 62	-	-	-	-	-	-	-	-	-	-	-	-	Vps62
MMS3_k127_2417886_0	315730.BcerKBAB4_5460	2.147e-64	236.0	COG1073@1|root,COG1073@2|Bacteria,1UJD3@1239|Firmicutes,4IT5U@91061|Bacilli,1ZKMR@1386|Bacillus	91061|Bacilli	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2417886_4	523850.TON_0839	1.023e-09	64.0	arCOG03909@1|root,arCOG03909@2157|Archaea,2Y7IC@28890|Euryarchaeota,245KA@183968|Thermococci	183968|Thermococci	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
MMS3_k127_2417886_2	383372.Rcas_2781	2.42e-26	109.0	COG5002@1|root,COG5002@2|Bacteria,2G8BE@200795|Chloroflexi,376H0@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_2419328_10	1120948.KB903220_gene96	4.827e-33	130.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4E1GQ@85010|Pseudonocardiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.1.400	ko:K20927	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
MMS3_k127_2419328_11	1194972.MVAC_15063	4.189e-23	106.0	2A7QB@1|root,30WP1@2|Bacteria,2IJVB@201174|Actinobacteria	201174|Actinobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
MMS3_k127_2419328_0	479434.Sthe_3286	2.275e-186	589.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi,27XHW@189775|Thermomicrobia	189775|Thermomicrobia	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
MMS3_k127_2419328_3	1382356.JQMP01000001_gene1057	6.811e-119	395.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi,27YUW@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_2419328_1	479434.Sthe_3283	9.53e-153	495.0	28HQ3@1|root,2Z7XW@2|Bacteria,2G9Q4@200795|Chloroflexi,27XYJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
MMS3_k127_2419328_2	266779.Meso_2656	3.159e-128	426.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2U8HJ@28211|Alphaproteobacteria,43P91@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
MMS3_k127_2419328_9	1054213.HMPREF9946_04134	4.969e-40	162.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria,2TRJZ@28211|Alphaproteobacteria,2JS5D@204441|Rhodospirillales	204441|Rhodospirillales	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
MMS3_k127_2419328_6	309801.trd_1345	4.529e-76	266.0	COG2141@1|root,COG2141@2|Bacteria,2G8CA@200795|Chloroflexi,27Y7R@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2419328_12	525904.Tter_2679	3.648e-22	111.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_2419328_5	765420.OSCT_1972	4.766e-84	307.0	COG1506@1|root,COG1506@2|Bacteria,2GAHG@200795|Chloroflexi,377JQ@32061|Chloroflexia	32061|Chloroflexia	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
MMS3_k127_2419328_8	1125863.JAFN01000001_gene2386	1.29e-51	187.0	COG0346@1|root,COG0346@2|Bacteria,1RJF9@1224|Proteobacteria,42TD6@68525|delta/epsilon subdivisions,2WP89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_2419328_7	1449351.RISW2_05805	2.131e-52	194.0	COG1028@1|root,COG1028@2|Bacteria,1R6S5@1224|Proteobacteria,2U353@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	short-chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_2424277_16	479434.Sthe_0920	2.534e-12	68.0	COG0106@1|root,COG0106@2|Bacteria,2G6EC@200795|Chloroflexi,27YB1@189775|Thermomicrobia	189775|Thermomicrobia	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMS3_k127_2424277_12	1382356.JQMP01000003_gene1936	1.438e-81	276.0	COG0118@1|root,COG0118@2|Bacteria,2G6FD@200795|Chloroflexi,27Y6F@189775|Thermomicrobia	189775|Thermomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMS3_k127_2424277_8	479434.Sthe_0918	6.442e-126	411.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,27XTE@189775|Thermomicrobia	189775|Thermomicrobia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
MMS3_k127_2424277_10	479434.Sthe_0916	2.265e-88	301.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi,27Y5G@189775|Thermomicrobia	189775|Thermomicrobia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
MMS3_k127_2424277_3	479434.Sthe_0915	2.152e-174	552.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi,27XRB@189775|Thermomicrobia	189775|Thermomicrobia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
MMS3_k127_2424277_9	479434.Sthe_0914	1.743e-90	302.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi,27Y7H@189775|Thermomicrobia	189775|Thermomicrobia	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
MMS3_k127_2424277_11	479434.Sthe_0913	1.914e-82	281.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi,27YCB@189775|Thermomicrobia	189775|Thermomicrobia	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
MMS3_k127_2424277_13	479434.Sthe_0912	4.367e-60	213.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,27YBZ@189775|Thermomicrobia	189775|Thermomicrobia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
MMS3_k127_2424277_2	1382356.JQMP01000003_gene1929	6.807e-182	582.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_2424277_7	479434.Sthe_0905	8.526e-134	434.0	COG0611@1|root,COG0611@2|Bacteria,2G6SH@200795|Chloroflexi,27XMF@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_2424277_5	479434.Sthe_0904	1.34e-141	460.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2424277_0	479434.Sthe_0903	0.0	1420.0	COG4581@1|root,COG4581@2|Bacteria,2G7P6@200795|Chloroflexi,27XJ5@189775|Thermomicrobia	189775|Thermomicrobia	L	DSHCT	-	-	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C
MMS3_k127_2424277_14	479434.Sthe_0902	1.484e-51	185.0	COG2128@1|root,COG2128@2|Bacteria,2GBF3@200795|Chloroflexi,27Z8Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_2424277_15	479434.Sthe_0901	8.211e-44	164.0	COG2153@1|root,COG2153@2|Bacteria,2G9IV@200795|Chloroflexi,27YGQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
MMS3_k127_2424277_1	479434.Sthe_0900	7.873e-227	712.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi,27XG0@189775|Thermomicrobia	189775|Thermomicrobia	E	argininosuccinate lyase	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
MMS3_k127_2424277_6	479434.Sthe_0899	1.497e-136	442.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi,27XQ4@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
MMS3_k127_2424277_4	118163.Ple7327_4099	7.886e-173	551.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,3VJCK@52604|Pleurocapsales	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
MMS3_k127_2434649_7	479434.Sthe_0482	1.015e-90	303.0	COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi,27Z3N@189775|Thermomicrobia	189775|Thermomicrobia	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
MMS3_k127_2434649_4	1121381.JNIV01000036_gene3341	8.584e-126	418.0	COG0624@1|root,COG0624@2|Bacteria,1WIRQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_2434649_2	479434.Sthe_0481	1.946e-195	612.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi,27Y22@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
MMS3_k127_2434649_5	479434.Sthe_0480	3.163e-117	381.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XV7@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_2434649_3	479434.Sthe_0479	4.309e-152	492.0	COG0438@1|root,COG0438@2|Bacteria,2G67A@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_2434649_11	479434.Sthe_0478	4.612e-58	213.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_2434649_1	479434.Sthe_0476	7.424e-212	665.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi,27XH4@189775|Thermomicrobia	189775|Thermomicrobia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
MMS3_k127_2434649_9	479434.Sthe_0474	1.241e-71	246.0	COG0521@1|root,COG0521@2|Bacteria,2G6YJ@200795|Chloroflexi,27Y8Y@189775|Thermomicrobia	189775|Thermomicrobia	H	May be involved in the biosynthesis of molybdopterin	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
MMS3_k127_2434649_12	479434.Sthe_0473	2.506e-37	145.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi,27YNS@189775|Thermomicrobia	189775|Thermomicrobia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
MMS3_k127_2434649_8	479434.Sthe_0472	2.488e-77	265.0	COG0164@1|root,COG0164@2|Bacteria,2G6KR@200795|Chloroflexi,27YAF@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
MMS3_k127_2434649_10	479434.Sthe_0471	3.812e-64	222.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi,27YD2@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
MMS3_k127_2434649_0	1382356.JQMP01000003_gene2146	1.842e-272	850.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi,27Z2G@189775|Thermomicrobia	189775|Thermomicrobia	E	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
MMS3_k127_2434649_6	479434.Sthe_0470	8.646e-102	334.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,27YAG@189775|Thermomicrobia	189775|Thermomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2434649_14	479434.Sthe_0469	2.744e-09	61.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	DUF756,TED
MMS3_k127_2437119_19	877424.ATWC01000006_gene272	1.39e-16	83.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	BPD_transp_2
MMS3_k127_2437119_18	1123277.KB893172_gene543	1.182e-18	102.0	COG3534@1|root,COG4386@1|root,COG4409@1|root,COG3534@2|Bacteria,COG4386@2|Bacteria,COG4409@2|Bacteria,4NEY7@976|Bacteroidetes,47Y73@768503|Cytophagia	976|Bacteroidetes	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
MMS3_k127_2437119_4	485913.Krac_4222	9.812e-102	367.0	COG1749@1|root,COG4409@1|root,COG1749@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	flgK	-	-	ko:K02388,ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ASH,DUF4082,Flg_bb_rod,Flg_bbr_C
MMS3_k127_2437119_16	1121423.JONT01000001_gene2161	3.217e-26	123.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,24AKU@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
MMS3_k127_2437119_21	1380356.JNIK01000003_gene1174	6.764e-07	55.0	29C55@1|root,2ZZ3Q@2|Bacteria,2HC01@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2437119_10	342949.PNA2_1651	5.253e-72	255.0	COG2355@1|root,arCOG04083@2157|Archaea,2XUXV@28890|Euryarchaeota,242R0@183968|Thermococci	183968|Thermococci	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMS3_k127_2437119_0	314345.SPV1_09118	4.029e-259	823.0	COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria	1224|Proteobacteria	G	glucan 1,4-alpha-glucosidase	cga	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_N,Glyco_hydro_15
MMS3_k127_2437119_7	1121918.ARWE01000001_gene3109	2.789e-92	310.0	COG1028@1|root,COG1028@2|Bacteria,1Q7EW@1224|Proteobacteria	1224|Proteobacteria	IQ	Short-chain dehydrogenase reductase Sdr	-	-	1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76	ko:K00034,ko:K00059,ko:K03366	ko00030,ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00030,map00061,map00333,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00572	R01520,R01521,R02855,R02946,R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671	RC00029,RC00066,RC00117,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_2437119_17	316274.Haur_2376	8.664e-19	90.0	2EM6G@1|root,33EVQ@2|Bacteria,2G9RV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2437119_2	344747.PM8797T_16258	5.754e-154	499.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2J1WY@203682|Planctomycetes	203682|Planctomycetes	C	COG1290 Cytochrome b subunit of the bc complex	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_CBB3
MMS3_k127_2437119_14	452637.Oter_3543	1.719e-55	198.0	COG0723@1|root,COG0723@2|Bacteria,46WMV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM Rieske 2Fe-2S domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
MMS3_k127_2437119_22	1123278.KB893387_gene4384	0.0003054	47.0	2CIBM@1|root,33NHZ@2|Bacteria,4NYXH@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
MMS3_k127_2437119_1	344747.PM8797T_16238	8.077e-243	773.0	COG0843@1|root,COG0843@2|Bacteria,2J2GN@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	COX1
MMS3_k127_2437119_9	452637.Oter_3540	2.979e-79	276.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,46W3S@74201|Verrucomicrobia,3K7PR@414999|Opitutae	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
MMS3_k127_2437119_12	479434.Sthe_2896	6.774e-61	221.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi,27Y50@189775|Thermomicrobia	200795|Chloroflexi	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_2437119_3	479434.Sthe_3439	1.847e-112	368.0	COG1028@1|root,COG1028@2|Bacteria,2G8II@200795|Chloroflexi,27XKN@189775|Thermomicrobia	200795|Chloroflexi	IQ	Dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_2437119_5	479434.Sthe_0272	2.864e-99	333.0	COG0491@1|root,COG0491@2|Bacteria,2GBAB@200795|Chloroflexi,27YH3@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_2437119_6	526227.Mesil_1129	9.274e-97	324.0	COG0697@1|root,COG0697@2|Bacteria,1WKUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2437119_13	1121127.JAFA01000093_gene2975	8.089e-58	220.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
MMS3_k127_2437119_11	309801.trd_A0408	2.355e-61	217.0	COG0717@1|root,COG0717@2|Bacteria,2G8PG@200795|Chloroflexi,27YDB@189775|Thermomicrobia	189775|Thermomicrobia	F	dUTPase	-	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
MMS3_k127_2437119_15	479434.Sthe_3463	8.742e-37	141.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	DAO,Fer2,Fer2_2,Fer2_4,Fer2_BFD,Fer4,Pyr_redox_2
MMS3_k127_2437119_8	479434.Sthe_3464	5.628e-82	284.0	COG0446@1|root,COG1251@1|root,COG0446@2|Bacteria,COG1251@2|Bacteria,2G6SN@200795|Chloroflexi,27YS3@189775|Thermomicrobia	189775|Thermomicrobia	C	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
MMS3_k127_2437119_20	479434.Sthe_3464	3.585e-14	74.0	COG0446@1|root,COG1251@1|root,COG0446@2|Bacteria,COG1251@2|Bacteria,2G6SN@200795|Chloroflexi,27YS3@189775|Thermomicrobia	189775|Thermomicrobia	C	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
MMS3_k127_2451891_2	272558.10174584	2.702e-07	63.0	COG0477@1|root,COG2814@2|Bacteria,1TQWM@1239|Firmicutes,4HB5B@91061|Bacilli,1ZAQX@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	tetB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K08168	-	M00704	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.16,2.A.1.3.22,2.A.1.3.6	-	-	MFS_1
MMS3_k127_2451891_0	485913.Krac_6021	3.996e-48	190.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
MMS3_k127_2451891_1	485913.Krac_2637	9.52e-22	102.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
MMS3_k127_2481486_10	479434.Sthe_1740	3.957e-59	211.0	COG0743@1|root,COG0743@2|Bacteria,2G5RB@200795|Chloroflexi,27Y4B@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
MMS3_k127_2481486_8	479434.Sthe_1739	7.572e-67	241.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi,27YD8@189775|Thermomicrobia	189775|Thermomicrobia	M	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
MMS3_k127_2481486_3	479434.Sthe_1738	3.039e-118	385.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi,27XF1@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
MMS3_k127_2481486_6	479434.Sthe_1737	2.079e-84	282.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi,27Y79@189775|Thermomicrobia	189775|Thermomicrobia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
MMS3_k127_2481486_2	309801.trd_1000	1.405e-118	387.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi,27XHK@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
MMS3_k127_2481486_7	479434.Sthe_1735	3.64e-72	248.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi,27Y81@189775|Thermomicrobia	189775|Thermomicrobia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
MMS3_k127_2481486_1	479434.Sthe_1734	1.186e-121	397.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi,27XHX@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
MMS3_k127_2481486_5	479434.Sthe_1733	1.058e-86	298.0	COG3103@1|root,COG4991@2|Bacteria,2GBHW@200795|Chloroflexi	200795|Chloroflexi	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
MMS3_k127_2481486_11	479434.Sthe_1732	5.617e-50	183.0	COG1664@1|root,COG1664@2|Bacteria,2GA19@200795|Chloroflexi,27YJF@189775|Thermomicrobia	189775|Thermomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMS3_k127_2481486_9	479434.Sthe_1731	5.04e-61	221.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi,27YJA@189775|Thermomicrobia	189775|Thermomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMS3_k127_2481486_12	479434.Sthe_1730	5.534e-18	86.0	2B9GT@1|root,322UT@2|Bacteria,2GBC8@200795|Chloroflexi,27YR6@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2481486_0	479434.Sthe_1728	1.361e-210	662.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi,27Y1I@189775|Thermomicrobia	189775|Thermomicrobia	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMS3_k127_2481486_4	1382356.JQMP01000003_gene2165	3.748e-97	321.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,27Y1D@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMS3_k127_2482476_7	443143.GM18_1870	5.553e-11	64.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42UAF@68525|delta/epsilon subdivisions,2WQGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH,Inositol_P
MMS3_k127_2482476_4	479434.Sthe_1981	6.85e-57	207.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
MMS3_k127_2482476_3	479434.Sthe_1984	4.61e-58	209.0	COG1443@1|root,COG1443@2|Bacteria,2G9TY@200795|Chloroflexi,27YIY@189775|Thermomicrobia	189775|Thermomicrobia	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_2482476_6	525904.Tter_0122	1.474e-38	149.0	COG1764@1|root,COG1764@2|Bacteria,2NQ0N@2323|unclassified Bacteria	2|Bacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
MMS3_k127_2482476_0	1121106.JQKB01000054_gene4466	7.729e-178	585.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2JPKU@204441|Rhodospirillales	204441|Rhodospirillales	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
MMS3_k127_2482476_5	479434.Sthe_2016	2.534e-48	178.0	COG0073@1|root,COG0073@2|Bacteria,2G74R@200795|Chloroflexi,27YK6@189775|Thermomicrobia	189775|Thermomicrobia	J	Putative tRNA binding domain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
MMS3_k127_2482476_2	479434.Sthe_2018	9.694e-123	401.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,27Y04@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMS3_k127_2482476_1	479434.Sthe_1762	5.96e-158	512.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2483717_0	1158150.KB906245_gene2124	0.0	1100.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1WWFC@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297	ko00071,ko00910,ko01120,map00071,map00910,map01120	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
MMS3_k127_2483717_1	1110502.TMO_2145	5.37e-20	93.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria,2JQF7@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K15576,ko:K22067	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
MMS3_k127_2485778_7	1536769.P40081_27470	2.112e-11	71.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
MMS3_k127_2485778_3	1214101.BN159_4447	1.086e-129	431.0	COG0476@1|root,COG0476@2|Bacteria,2GNQE@201174|Actinobacteria	201174|Actinobacteria	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
MMS3_k127_2485778_2	323097.Nham_4501	4.182e-162	521.0	COG0226@1|root,COG0226@2|Bacteria,1PGT2@1224|Proteobacteria,2TURV@28211|Alphaproteobacteria,3JVQ6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Meiotically up-regulated gene 113	-	-	-	-	-	-	-	-	-	-	-	-	MUG113,T5orf172
MMS3_k127_2485778_1	316273.XCV2166	0.0	1234.0	COG1061@1|root,COG1061@2|Bacteria,1PPCG@1224|Proteobacteria,1RPSB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
MMS3_k127_2485778_0	75379.Tint_1545	0.0	1459.0	COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,2VMKD@28216|Betaproteobacteria	28216|Betaproteobacteria	V	type II restriction enzyme, methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
MMS3_k127_2487823_2	479434.Sthe_1259	0.0001843	46.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi,27Y2D@189775|Thermomicrobia	189775|Thermomicrobia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
MMS3_k127_2487823_1	1382356.JQMP01000003_gene2500	4.244e-39	149.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi,27YJU@189775|Thermomicrobia	189775|Thermomicrobia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
MMS3_k127_2487823_0	479434.Sthe_1257	2.132e-293	906.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi,27XWF@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
MMS3_k127_2505363_1	1382356.JQMP01000004_gene274	2.155e-73	251.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi,27Y2G@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_2505363_0	479434.Sthe_1462	1.515e-240	760.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi,27Y2G@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_2505363_2	479434.Sthe_3494	3.76e-60	215.0	COG1802@1|root,COG1802@2|Bacteria,2GBFN@200795|Chloroflexi,27ZBU@189775|Thermomicrobia	189775|Thermomicrobia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
MMS3_k127_2505363_3	570268.ANBB01000063_gene902	8.695e-58	206.0	COG5553@1|root,COG5553@2|Bacteria,2I8K9@201174|Actinobacteria,4EJRG@85012|Streptosporangiales	201174|Actinobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
MMS3_k127_2505363_5	1173027.Mic7113_2082	1.009e-36	151.0	COG0454@1|root,COG0456@2|Bacteria,1G407@1117|Cyanobacteria,1H9GX@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_2505363_6	344747.PM8797T_14716	1.209e-14	81.0	2DX6Z@1|root,343NZ@2|Bacteria	2|Bacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
MMS3_k127_2505363_4	298654.FraEuI1c_5444	1.3e-57	205.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4EUAR@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.7	ko:K15868	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2507937_12	1150398.JIBJ01000003_gene1602	2.104e-06	50.0	COG0580@1|root,COG0580@2|Bacteria,2IG6C@201174|Actinobacteria	201174|Actinobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
MMS3_k127_2507937_8	1040989.AWZU01000004_gene7082	2.874e-61	218.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TUEF@28211|Alphaproteobacteria,3JT5U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	MA20_15005	-	4.1.1.79	ko:K13039	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_2507937_9	1380355.JNIJ01000009_gene1663	9.711e-46	172.0	COG4032@1|root,COG4032@2|Bacteria,1R53S@1224|Proteobacteria,2TT20@28211|Alphaproteobacteria,3JTZJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	MA20_15000	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
MMS3_k127_2507937_6	485913.Krac_7021	3.649e-75	267.0	COG4099@1|root,COG4099@2|Bacteria	2|Bacteria	F	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Esterase,Esterase_phd,Peptidase_S9
MMS3_k127_2507937_4	485913.Krac_7304	5.432e-85	297.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	vanT	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5,Acyl_transf_3
MMS3_k127_2507937_0	1382306.JNIM01000001_gene3359	1.23e-142	469.0	COG0318@1|root,COG0318@2|Bacteria,2G83V@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2507937_11	215803.DB30_5694	7.021e-20	96.0	COG1510@1|root,COG1510@2|Bacteria,1NBU1@1224|Proteobacteria,432HI@68525|delta/epsilon subdivisions,2WY24@28221|Deltaproteobacteria,2YW09@29|Myxococcales	28221|Deltaproteobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repress,MarR_2
MMS3_k127_2507937_1	1382306.JNIM01000001_gene464	1.745e-119	391.0	COG1131@1|root,COG1131@2|Bacteria,2G5QI@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2507937_5	1382306.JNIM01000001_gene463	1.499e-82	295.0	COG3559@1|root,COG3559@2|Bacteria,2G7I8@200795|Chloroflexi	200795|Chloroflexi	M	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_2507937_10	1382306.JNIM01000001_gene1660	9.801e-38	156.0	COG0006@1|root,COG0006@2|Bacteria,2G6AE@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the peptidase M24B family	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_2507937_7	1382356.JQMP01000003_gene1570	2.95e-64	224.0	COG0288@1|root,COG0288@2|Bacteria,2G8Q4@200795|Chloroflexi	200795|Chloroflexi	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
MMS3_k127_2507937_2	479434.Sthe_2325	8.193e-110	364.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_2507937_3	357808.RoseRS_3950	2.391e-97	325.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
MMS3_k127_251267_4	479434.Sthe_0072	2.952e-78	295.0	COG0457@1|root,COG1396@1|root,COG3899@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	2|Bacteria	K	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,HTH_19,HTH_3,HTH_31
MMS3_k127_251267_3	479434.Sthe_1973	5.231e-88	297.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi,27YAS@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_251267_0	479434.Sthe_1974	1.6e-288	898.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
MMS3_k127_251267_1	479434.Sthe_0130	2.737e-196	618.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi	200795|Chloroflexi	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_251267_2	485913.Krac_4995	3.685e-154	500.0	COG1167@1|root,COG1167@2|Bacteria,2G5XE@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
MMS3_k127_2519079_3	479434.Sthe_3090	2.367e-65	232.0	COG3693@1|root,COG3693@2|Bacteria,2GBGU@200795|Chloroflexi,27Y52@189775|Thermomicrobia	200795|Chloroflexi	M	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
MMS3_k127_2519079_0	479434.Sthe_3518	1.091e-194	614.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,27XXR@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.3.1.13	ko:K15526	-	-	-	-	ko00000,ko01000	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
MMS3_k127_2519079_4	479434.Sthe_3517	5.133e-24	104.0	COG1225@1|root,COG1225@2|Bacteria,2GA1B@200795|Chloroflexi,27YM1@189775|Thermomicrobia	189775|Thermomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
MMS3_k127_2519079_2	479434.Sthe_0424	2.541e-86	294.0	COG0010@1|root,COG0010@2|Bacteria,2G8DY@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_2519079_1	479434.Sthe_0424	3.139e-94	318.0	COG0010@1|root,COG0010@2|Bacteria,2G8DY@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_2519079_5	309801.trd_1911	0.0003157	46.0	COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi,27Y53@189775|Thermomicrobia	189775|Thermomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_2527910_3	479434.Sthe_2145	1.678e-100	342.0	COG2211@1|root,COG2211@2|Bacteria,2G7ZY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2527910_0	479434.Sthe_2456	4.879e-194	619.0	COG0741@1|root,COG0741@2|Bacteria,2G9ZE@200795|Chloroflexi,27XR3@189775|Thermomicrobia	189775|Thermomicrobia	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2527910_7	485913.Krac_6589	7.116e-38	147.0	2BQKI@1|root,32JGJ@2|Bacteria,2G9SN@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_2527910_5	1347086.CCBA010000015_gene562	2.586e-57	202.0	COG0346@1|root,COG0346@2|Bacteria,1V4ST@1239|Firmicutes,4HHEE@91061|Bacilli,1ZG9I@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_2527910_4	479434.Sthe_2460	1.869e-61	222.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi,27YP2@189775|Thermomicrobia	189775|Thermomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS3_k127_2527910_1	479434.Sthe_2724	6.69e-178	567.0	COG0665@1|root,COG0665@2|Bacteria,2G7Z9@200795|Chloroflexi	200795|Chloroflexi	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_2527910_2	330084.JNYZ01000001_gene3252	6.778e-136	459.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
MMS3_k127_2527910_6	1042877.GQS_02930	2.168e-38	154.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota	28890|Euryarchaeota	S	metal-dependent membrane protease	-	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0071944,GO:0080120,GO:0140096,GO:1901564	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
MMS3_k127_2537756_3	479434.Sthe_2069	4.418e-18	86.0	COG0477@1|root,COG2814@2|Bacteria,2G8WA@200795|Chloroflexi,27Z1K@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2537756_2	479434.Sthe_2069	2.166e-23	103.0	COG0477@1|root,COG2814@2|Bacteria,2G8WA@200795|Chloroflexi,27Z1K@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2537756_0	1183438.GKIL_4202	8.23e-201	640.0	COG4108@1|root,COG4108@2|Bacteria,1G0Y8@1117|Cyanobacteria	1117|Cyanobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
MMS3_k127_2537756_1	63737.Npun_F5939	3.376e-70	243.0	COG1051@1|root,COG1051@2|Bacteria,1G4H7@1117|Cyanobacteria,1HMRB@1161|Nostocales	1117|Cyanobacteria	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
MMS3_k127_2547952_2	867845.KI911784_gene2764	2.934e-157	507.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
MMS3_k127_2547952_0	479434.Sthe_2936	9.751e-285	884.0	COG1164@1|root,COG1164@2|Bacteria,2G60A@200795|Chloroflexi,27XYR@189775|Thermomicrobia	189775|Thermomicrobia	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
MMS3_k127_2547952_6	309801.trd_A0913	4.687e-35	138.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
MMS3_k127_2547952_5	479434.Sthe_2931	1.122e-106	351.0	COG0253@1|root,COG0253@2|Bacteria,2G99B@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
MMS3_k127_2547952_1	479434.Sthe_2905	1.299e-185	583.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,27XFT@189775|Thermomicrobia	189775|Thermomicrobia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_2547952_8	1444711.CCJF01000005_gene973	6.792e-06	48.0	COG0861@1|root,COG0861@2|Bacteria,2JGIA@204428|Chlamydiae	204428|Chlamydiae	P	Integral membrane protein TerC family	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
MMS3_k127_2547952_9	608538.HTH_1675	0.0005285	46.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
MMS3_k127_2547952_7	469383.Cwoe_1892	3.219e-10	67.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4CTQS@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMS3_k127_2547952_3	479434.Sthe_2677	6.297e-153	497.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi,27Y2E@189775|Thermomicrobia	189775|Thermomicrobia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMS3_k127_2547952_4	479434.Sthe_2679	1.172e-138	454.0	COG2211@1|root,COG2211@2|Bacteria,2GA6Q@200795|Chloroflexi,27Y8E@189775|Thermomicrobia	189775|Thermomicrobia	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2548438_3	479434.Sthe_2033	2.735e-82	281.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2548438_4	1121104.AQXH01000008_gene2376	1.129e-06	53.0	2ESUZ@1|root,33KDD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2548438_0	479434.Sthe_3502	5.92e-134	432.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi,27XF7@189775|Thermomicrobia	2|Bacteria	C	Proline dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046983,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
MMS3_k127_2548438_1	485913.Krac_8957	1.84e-87	306.0	COG2211@1|root,COG2211@2|Bacteria,2GBJQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2548438_2	330084.JNYZ01000046_gene1926	1.2e-85	291.0	COG1024@1|root,COG1024@2|Bacteria,2H25N@201174|Actinobacteria,4EBYU@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_2555024_22	479434.Sthe_1934	3.94e-12	66.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi,27Y12@189775|Thermomicrobia	189775|Thermomicrobia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMS3_k127_2555024_2	479434.Sthe_1933	9.113e-176	564.0	COG0508@1|root,COG0508@2|Bacteria,2G619@200795|Chloroflexi,27Y2C@189775|Thermomicrobia	189775|Thermomicrobia	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
MMS3_k127_2555024_21	1150600.ADIARSV_1346	1.43e-17	98.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,1IP94@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
MMS3_k127_2555024_14	479434.Sthe_2369	6.74e-71	249.0	2A4QG@1|root,30TBR@2|Bacteria,2GB9Y@200795|Chloroflexi,27YEP@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2555024_12	479434.Sthe_2370	3.88e-105	351.0	COG1994@1|root,COG1994@2|Bacteria,2GBF1@200795|Chloroflexi,27Z8Q@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2555024_6	479434.Sthe_2371	2.163e-138	446.0	COG2189@1|root,COG2189@2|Bacteria,2G5WR@200795|Chloroflexi	200795|Chloroflexi	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
MMS3_k127_2555024_4	1382356.JQMP01000003_gene1996	5.42e-147	472.0	COG2008@1|root,COG2008@2|Bacteria,2G7UV@200795|Chloroflexi,27XVE@189775|Thermomicrobia	2|Bacteria	E	Beta-eliminating lyase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
MMS3_k127_2555024_16	479434.Sthe_0690	1.151e-59	213.0	COG1670@1|root,COG1670@2|Bacteria,2G73Y@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_2555024_5	479434.Sthe_2373	1.009e-139	456.0	COG5542@1|root,COG5542@2|Bacteria,2G72S@200795|Chloroflexi	200795|Chloroflexi	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
MMS3_k127_2555024_11	479434.Sthe_2376	7.663e-115	374.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi,27XPU@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMS3_k127_2555024_3	386456.JQKN01000007_gene3251	1.569e-155	506.0	arCOG02685@1|root,arCOG02685@2157|Archaea,2XV10@28890|Euryarchaeota	28890|Euryarchaeota	G	COG0477 Permeases of the major facilitator superfamily	csbC	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
MMS3_k127_2555024_1	479434.Sthe_2380	3.492e-240	752.0	COG0513@1|root,COG0513@2|Bacteria,2G5VR@200795|Chloroflexi,27XXB@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
MMS3_k127_2555024_0	479434.Sthe_2381	0.0	1086.0	COG0365@1|root,COG0365@2|Bacteria,2G830@200795|Chloroflexi,27XH3@189775|Thermomicrobia	189775|Thermomicrobia	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS3_k127_2555024_20	1122609.AUGT01000003_gene2168	1.77e-18	89.0	COG0346@1|root,COG3832@1|root,COG0346@2|Bacteria,COG3832@2|Bacteria,2IHY4@201174|Actinobacteria,4DWKV@85009|Propionibacteriales	201174|Actinobacteria	E	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMS3_k127_2555024_18	479434.Sthe_2183	5.643e-44	163.0	COG1547@1|root,COG1547@2|Bacteria,2GAFU@200795|Chloroflexi,27YQW@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
MMS3_k127_2555024_9	479434.Sthe_2188	1.185e-126	417.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_2555024_17	479434.Sthe_2189	2.972e-58	208.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi,27YIE@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2555024_13	479434.Sthe_2190	4.124e-76	270.0	COG5662@1|root,COG5662@2|Bacteria,2G7G7@200795|Chloroflexi,27YCS@189775|Thermomicrobia	189775|Thermomicrobia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2555024_7	479434.Sthe_2191	7.715e-137	443.0	COG1131@1|root,COG1131@2|Bacteria,2G69S@200795|Chloroflexi,27XTG@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2555024_10	479434.Sthe_2192	5.136e-118	386.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi,27Y36@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_2555024_15	479434.Sthe_2193	5.69e-63	222.0	COG0491@1|root,COG0491@2|Bacteria,2G6X9@200795|Chloroflexi,27YDW@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_2555024_8	479434.Sthe_2302	2.907e-130	424.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
MMS3_k127_2561878_2	1128421.JAGA01000004_gene2704	1.804e-92	318.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_2561878_4	316067.Geob_1693	1.827e-40	154.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
MMS3_k127_2561878_0	1144275.COCOR_03165	0.0	1310.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GT	Phosphoenolpyruvate synthase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
MMS3_k127_2561878_1	1121374.KB891576_gene646	4.269e-109	378.0	COG1680@1|root,COG1680@2|Bacteria,1MWHS@1224|Proteobacteria,1RRQF@1236|Gammaproteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_2561878_5	1041159.AZUW01000005_gene5427	4.354e-33	134.0	2B3U0@1|root,31WHT@2|Bacteria,1RIS2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2561878_6	324602.Caur_0547	1.119e-05	52.0	299CS@1|root,2ZWFP@2|Bacteria,2G9JC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2561878_3	926550.CLDAP_35570	1.947e-70	245.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_2568531_7	479434.Sthe_1204	1.607e-61	216.0	COG2109@1|root,COG2109@2|Bacteria,2GAN9@200795|Chloroflexi,27Y93@189775|Thermomicrobia	189775|Thermomicrobia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
MMS3_k127_2568531_0	479434.Sthe_1205	6.41e-286	885.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi,27XPT@189775|Thermomicrobia	200795|Chloroflexi	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
MMS3_k127_2568531_6	479434.Sthe_1206	1.351e-61	215.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi,27YE6@189775|Thermomicrobia	189775|Thermomicrobia	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
MMS3_k127_2568531_2	479434.Sthe_1207	2.438e-118	388.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi,27YEF@189775|Thermomicrobia	189775|Thermomicrobia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
MMS3_k127_2568531_4	1382306.JNIM01000001_gene631	1.132e-71	250.0	COG1691@1|root,COG1691@2|Bacteria,2G6SZ@200795|Chloroflexi	200795|Chloroflexi	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
MMS3_k127_2568531_3	479434.Sthe_1208	5.929e-106	351.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,27XW2@189775|Thermomicrobia	189775|Thermomicrobia	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
MMS3_k127_2568531_5	479434.Sthe_1209	1.288e-62	221.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi,27YFU@189775|Thermomicrobia	189775|Thermomicrobia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
MMS3_k127_2568531_1	479434.Sthe_1210	4.181e-163	527.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27Y4V@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_257135_7	479434.Sthe_2043	4.761e-66	232.0	COG1595@1|root,COG1595@2|Bacteria,2GA1X@200795|Chloroflexi,27YQ5@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_257135_2	479434.Sthe_2591	1.802e-127	419.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_257135_8	251221.35213174	3.652e-65	231.0	COG1216@1|root,COG1216@2|Bacteria,1G6GW@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_257135_1	1382356.JQMP01000003_gene1924	1.744e-135	438.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi,27YUK@189775|Thermomicrobia	189775|Thermomicrobia	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
MMS3_k127_257135_6	1382356.JQMP01000003_gene1925	3.039e-75	261.0	COG0321@1|root,COG0321@2|Bacteria,2G8KT@200795|Chloroflexi,27Z4I@189775|Thermomicrobia	189775|Thermomicrobia	H	Biotin/lipoate A/B protein ligase family	-	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
MMS3_k127_257135_0	479434.Sthe_2045	2.875e-167	535.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	imuB	-	2.7.7.7	ko:K02346,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS
MMS3_k127_257135_11	1082933.MEA186_01673	3.856e-36	144.0	COG1309@1|root,COG1309@2|Bacteria,1RBV0@1224|Proteobacteria,2U7VY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_257135_5	882083.SacmaDRAFT_1903	1.642e-96	326.0	COG2141@1|root,COG2141@2|Bacteria,2IAC9@201174|Actinobacteria,4DY34@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_257135_12	1033736.CAHK01000041_gene266	7.855e-31	131.0	COG0500@1|root,COG2226@2|Bacteria,2I5DJ@201174|Actinobacteria,4F893@85019|Brevibacteriaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_257135_3	105420.BBPO01000011_gene1963	2.268e-116	382.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,2NHNG@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_257135_9	105420.BBPO01000011_gene1962	1.176e-61	222.0	COG0842@1|root,COG0842@2|Bacteria,2GJ2G@201174|Actinobacteria,2NJN8@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_257135_10	479434.Sthe_1708	1.794e-40	158.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,27Z8D@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
MMS3_k127_257135_4	479434.Sthe_2047	2.712e-112	364.0	COG0714@1|root,COG0714@2|Bacteria,2G9S0@200795|Chloroflexi	200795|Chloroflexi	S	AAA domain (dynein-related subfamily)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5
MMS3_k127_2586826_2	479434.Sthe_1517	1.258e-158	508.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi,27XI0@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
MMS3_k127_2586826_6	278957.ABEA03000106_gene1816	9.599e-93	317.0	COG1680@1|root,COG1680@2|Bacteria,46ZC7@74201|Verrucomicrobia,3KA14@414999|Opitutae	414999|Opitutae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_2586826_7	479434.Sthe_1516	1.608e-40	157.0	2A4R3@1|root,30TCF@2|Bacteria,2GBAR@200795|Chloroflexi,27YJN@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2586826_5	479434.Sthe_1514	2.918e-106	349.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi,27XZY@189775|Thermomicrobia	189775|Thermomicrobia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
MMS3_k127_2586826_1	479434.Sthe_1513	3.769e-236	741.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,27YYI@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_2586826_0	479434.Sthe_1506	3.529e-268	835.0	COG1574@1|root,COG1574@2|Bacteria,2GB76@200795|Chloroflexi,27XM1@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_2586826_3	309801.trd_0390	3.716e-115	376.0	COG0726@1|root,COG0726@2|Bacteria,2GB8A@200795|Chloroflexi,27XZW@189775|Thermomicrobia	2|Bacteria	G	polysaccharide deacetylase	cda1	GO:0000003,GO:0000272,GO:0003006,GO:0005575,GO:0005618,GO:0005619,GO:0005623,GO:0005631,GO:0005975,GO:0005976,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006037,GO:0006039,GO:0006040,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009272,GO:0009277,GO:0009653,GO:0009987,GO:0010383,GO:0010927,GO:0016043,GO:0016052,GO:0016998,GO:0017144,GO:0019953,GO:0022402,GO:0022411,GO:0022413,GO:0022414,GO:0022607,GO:0030154,GO:0030312,GO:0030435,GO:0030437,GO:0030476,GO:0031160,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0034218,GO:0034232,GO:0034293,GO:0042244,GO:0042546,GO:0042737,GO:0043170,GO:0043934,GO:0043935,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044277,GO:0044426,GO:0044462,GO:0044464,GO:0044703,GO:0045229,GO:0046348,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0070590,GO:0070591,GO:0070726,GO:0070910,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071852,GO:0071853,GO:0071854,GO:0071940,GO:0071944,GO:0071966,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903046	1.7.3.3,3.5.1.41,3.5.2.5	ko:K00365,ko:K01452,ko:K16842	ko00230,ko00232,ko00520,ko01100,ko01120,map00230,map00232,map00520,map01100,map01120	M00546	R02106,R02333,R02425,R07981	RC00166,RC00300,RC00680,RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox,Polysacc_deac_1
MMS3_k127_2586826_4	479434.Sthe_1501	1.568e-109	357.0	COG1402@1|root,COG1402@2|Bacteria,2G7B0@200795|Chloroflexi,27Y94@189775|Thermomicrobia	189775|Thermomicrobia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_2590691_0	1120950.KB892793_gene2376	3.762e-158	501.0	COG4030@1|root,COG4030@2|Bacteria,2GJFD@201174|Actinobacteria,4DQEP@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
MMS3_k127_2590691_2	378806.STAUR_5280	2.602e-87	302.0	COG1846@1|root,COG1846@2|Bacteria,1N6YD@1224|Proteobacteria,433TH@68525|delta/epsilon subdivisions,2X3E9@28221|Deltaproteobacteria,2YVPE@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
MMS3_k127_2590691_4	926550.CLDAP_16890	1.623e-30	129.0	COG0406@1|root,COG0406@2|Bacteria,2G726@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
MMS3_k127_2590691_6	1463841.JOIR01000026_gene260	7.111e-16	81.0	2B33I@1|root,2ZJBV@2|Bacteria,2GW38@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2590691_5	37727.XP_002153547.1	2.282e-17	87.0	COG0394@1|root,2S4HS@2759|Eukaryota,3A9I9@33154|Opisthokonta,3P94H@4751|Fungi,3QZKS@4890|Ascomycota,20HHW@147545|Eurotiomycetes,3S8X2@5042|Eurotiales	4751|Fungi	E	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
MMS3_k127_2590691_1	309801.trd_1331	3.189e-113	385.0	COG0405@1|root,COG0405@2|Bacteria,2GABC@200795|Chloroflexi,27XH8@189775|Thermomicrobia	189775|Thermomicrobia	E	TIGRFAM gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_2590691_3	1238425.J07HQW2_00965	3.716e-39	149.0	COG0819@1|root,arCOG01128@2157|Archaea,2XTG7@28890|Euryarchaeota,23STS@183963|Halobacteria	183963|Halobacteria	K	transcription activator	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
MMS3_k127_2601521_5	1157490.EL26_07945	4.198e-19	89.0	COG2329@1|root,COG2329@2|Bacteria,1VFB7@1239|Firmicutes,4HQAG@91061|Bacilli,27AGI@186823|Alicyclobacillaceae	91061|Bacilli	S	Antibiotic biosynthesis monooxygenase	-	-	1.14.99.48	ko:K07145	ko00860,ko01110,map00860,map01110	-	R10468,R10510	RC03185	ko00000,ko00001,ko01000	-	-	-	ABM
MMS3_k127_2601521_6	880073.Calab_3316	2.835e-05	50.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
MMS3_k127_2601521_4	1410631.JHWZ01000006_gene343	1.486e-54	209.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,27IRR@186928|unclassified Lachnospiraceae	186801|Clostridia	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
MMS3_k127_2601521_2	479434.Sthe_0092	6.569e-137	452.0	COG2223@1|root,COG2223@2|Bacteria,2GBND@200795|Chloroflexi,27XPQ@189775|Thermomicrobia	189775|Thermomicrobia	P	PUCC protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2601521_0	479434.Sthe_0108	6.527e-159	508.0	COG2159@1|root,COG2159@2|Bacteria,2G8UX@200795|Chloroflexi,27Z57@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
MMS3_k127_2601521_3	66692.ABC3653	1.529e-102	349.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,1ZFU7@1386|Bacillus	91061|Bacilli	S	Peptidase dimerisation domain	-	-	-	ko:K12941,ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_2601521_1	1123242.JH636435_gene2136	1.458e-157	519.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2IYRX@203682|Planctomycetes	203682|Planctomycetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
MMS3_k127_260231_1	479434.Sthe_1001	2.596e-169	540.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi,27XGW@189775|Thermomicrobia	189775|Thermomicrobia	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2,RNase_T
MMS3_k127_260231_2	479434.Sthe_1000	7.005e-148	477.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi,27Y1X@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_260231_5	309801.trd_0333	1.238e-50	183.0	COG2009@1|root,COG2009@2|Bacteria,2G7CW@200795|Chloroflexi,27YF5@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMS3_k127_260231_4	479434.Sthe_0998	5.584e-59	207.0	COG2142@1|root,COG2142@2|Bacteria,2G7EN@200795|Chloroflexi,27YCT@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMS3_k127_260231_0	479434.Sthe_0997	1.1e-322	992.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,27XUB@189775|Thermomicrobia	189775|Thermomicrobia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_260231_3	309801.trd_0330	5.85e-121	392.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi,27XI2@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10
MMS3_k127_260231_6	1382356.JQMP01000003_gene2362	3.135e-34	138.0	COG0671@1|root,COG0671@2|Bacteria,2GA1H@200795|Chloroflexi,27YMX@189775|Thermomicrobia	189775|Thermomicrobia	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2617847_5	479434.Sthe_0001	1.203e-66	230.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi,27XP6@189775|Thermomicrobia	189775|Thermomicrobia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
MMS3_k127_2617847_1	309801.trd_A0396	1.663e-161	515.0	COG1834@1|root,COG1834@2|Bacteria,2G9XN@200795|Chloroflexi,27YVU@189775|Thermomicrobia	189775|Thermomicrobia	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
MMS3_k127_2617847_0	357808.RoseRS_4510	1.898e-167	539.0	COG0370@1|root,COG0370@2|Bacteria,2GBTA@200795|Chloroflexi,37667@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
MMS3_k127_2617847_2	357808.RoseRS_4511	5.745e-96	323.0	COG0370@1|root,COG0370@2|Bacteria,2GAJB@200795|Chloroflexi,376HM@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_N
MMS3_k127_2617847_6	357808.RoseRS_4512	6.243e-53	200.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
MMS3_k127_2617847_3	479434.Sthe_0209	1.665e-77	262.0	COG0221@1|root,COG0221@2|Bacteria,2G6T4@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
MMS3_k127_2617847_4	479434.Sthe_2063	1.204e-69	243.0	COG1573@1|root,COG1573@2|Bacteria,2G8Q5@200795|Chloroflexi	200795|Chloroflexi	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_2617847_7	1382356.JQMP01000004_gene572	3.417e-13	77.0	2A4W4@1|root,30THT@2|Bacteria,2GBFT@200795|Chloroflexi,27ZC6@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2623058_3	1218173.BALCAV_0218725	8.757e-21	97.0	COG3427@1|root,COG3427@2|Bacteria,1V817@1239|Firmicutes,4HJA1@91061|Bacilli,1ZH31@1386|Bacillus	91061|Bacilli	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	-	-	-	-	-	-	-	-	-	COXG,Polyketide_cyc2
MMS3_k127_2623058_0	479434.Sthe_2689	5.221e-203	638.0	COG1454@1|root,COG1454@2|Bacteria,2G6IU@200795|Chloroflexi,27YUC@189775|Thermomicrobia	189775|Thermomicrobia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.99.24	ko:K11173	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
MMS3_k127_2623058_1	477641.MODMU_4191	1.2e-127	422.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4EV6E@85013|Frankiales	201174|Actinobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
MMS3_k127_2623058_2	1499968.TCA2_0732	9.479e-103	342.0	COG2421@1|root,COG2421@2|Bacteria,1TQ67@1239|Firmicutes,4HA9D@91061|Bacilli,26VMV@186822|Paenibacillaceae	91061|Bacilli	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
MMS3_k127_2628407_0	479434.Sthe_0826	1.43e-202	639.0	COG0644@1|root,COG0644@2|Bacteria,2G68K@200795|Chloroflexi,27XS1@189775|Thermomicrobia	189775|Thermomicrobia	C	HI0933-like protein	-	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO
MMS3_k127_2628407_1	479434.Sthe_0825	1.428e-102	343.0	COG2025@1|root,COG2025@2|Bacteria,2G6PP@200795|Chloroflexi,27XU4@189775|Thermomicrobia	189775|Thermomicrobia	C	Electron transfer flavoprotein	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
MMS3_k127_2628407_2	479434.Sthe_0824	1.098e-86	293.0	COG2086@1|root,COG2086@2|Bacteria,2G72U@200795|Chloroflexi,27XPK@189775|Thermomicrobia	189775|Thermomicrobia	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
MMS3_k127_2628407_3	479434.Sthe_0823	1.711e-18	85.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi,27XKS@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
MMS3_k127_2628750_1	479434.Sthe_1030	3.045e-262	817.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,27Y0B@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMS3_k127_2628750_0	479434.Sthe_1029	0.0	1978.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi,27XNX@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
MMS3_k127_2628750_5	479434.Sthe_1028	4.965e-60	213.0	COG3815@1|root,COG3815@2|Bacteria,2G73B@200795|Chloroflexi,27Z7M@189775|Thermomicrobia	189775|Thermomicrobia	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
MMS3_k127_2628750_2	479434.Sthe_1027	2.481e-144	467.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi,27XWG@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
MMS3_k127_2628750_6	479434.Sthe_1025	2.812e-11	64.0	2A4SQ@1|root,30TE4@2|Bacteria,2GA2D@200795|Chloroflexi,27YRP@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2628750_3	479434.Sthe_1024	1.095e-131	431.0	COG1503@1|root,COG1503@2|Bacteria,2G745@200795|Chloroflexi,27XGI@189775|Thermomicrobia	189775|Thermomicrobia	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_2
MMS3_k127_2628750_4	479434.Sthe_1023	1.076e-71	255.0	COG1597@1|root,COG1597@2|Bacteria,2G77V@200795|Chloroflexi,27YF1@189775|Thermomicrobia	189775|Thermomicrobia	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
MMS3_k127_2652174_5	864069.MicloDRAFT_00013020	4.396e-42	166.0	COG4124@1|root,COG4124@2|Bacteria,1QH7T@1224|Proteobacteria,2TUE3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Glyco_hydro_26
MMS3_k127_2652174_3	1382356.JQMP01000003_gene2337	4.835e-58	222.0	COG3858@1|root,COG3858@2|Bacteria,2G7HP@200795|Chloroflexi,27XZM@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycoside hydrolase, family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
MMS3_k127_2652174_1	479434.Sthe_1830	2.682e-167	540.0	COG1070@1|root,COG1070@2|Bacteria,2G5KJ@200795|Chloroflexi,27XI8@189775|Thermomicrobia	189775|Thermomicrobia	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
MMS3_k127_2652174_2	562970.Btus_2414	9.824e-101	331.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
MMS3_k127_2652174_0	479434.Sthe_1822	9.523e-221	696.0	COG0154@1|root,COG0154@2|Bacteria,2G82J@200795|Chloroflexi,27XKT@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_2652174_6	381666.H16_B1607	0.0002263	49.0	COG3629@1|root,COG3899@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,1MUDT@1224|Proteobacteria,2VPH8@28216|Betaproteobacteria,1KCSE@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
MMS3_k127_2658336_1	479434.Sthe_2693	1.109e-161	519.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_2658336_0	383372.Rcas_3672	3.716e-180	573.0	COG0626@1|root,COG0626@2|Bacteria,2G7Q6@200795|Chloroflexi,3770M@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_2658336_3	1122138.AQUZ01000011_gene5020	1.656e-120	400.0	COG2072@1|root,COG2072@2|Bacteria,2GJWE@201174|Actinobacteria,4DRR6@85009|Propionibacteriales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	K_oxygenase,Pyr_redox_2,Pyr_redox_3
MMS3_k127_2658336_4	479434.Sthe_1149	1.906e-96	332.0	COG3919@1|root,COG3919@2|Bacteria,2G80M@200795|Chloroflexi	200795|Chloroflexi	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2658336_2	479434.Sthe_2105	2.126e-157	502.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi,27XU0@189775|Thermomicrobia	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
MMS3_k127_2658336_5	1218173.BALCAV_0218725	3.638e-20	97.0	COG3427@1|root,COG3427@2|Bacteria,1V817@1239|Firmicutes,4HJA1@91061|Bacilli,1ZH31@1386|Bacillus	91061|Bacilli	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	-	-	-	-	-	-	-	-	-	COXG,Polyketide_cyc2
MMS3_k127_2679838_0	479434.Sthe_1588	3.234e-248	788.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,27XNH@189775|Thermomicrobia	189775|Thermomicrobia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
MMS3_k127_2679838_1	321332.CYB_1353	7.483e-61	222.0	COG0524@1|root,COG0524@2|Bacteria,1G2YU@1117|Cyanobacteria,1H46E@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_2704833_1	1415754.JQMK01000006_gene3794	7.006e-33	140.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
MMS3_k127_2704833_2	224911.27353725	5.277e-23	104.0	2AIA2@1|root,318QU@2|Bacteria,1Q7YI@1224|Proteobacteria,2UUUF@28211|Alphaproteobacteria,3K4UB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Immunity protein 8	-	-	-	-	-	-	-	-	-	-	-	-	Imm8
MMS3_k127_2704833_0	635013.TherJR_0239	9.166e-140	460.0	COG1032@1|root,COG1032@2|Bacteria,1UZQC@1239|Firmicutes,24PDA@186801|Clostridia	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMS3_k127_2725055_17	479434.Sthe_0651	5.251e-23	100.0	COG0828@1|root,COG0828@2|Bacteria,2GB57@200795|Chloroflexi,27YPA@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
MMS3_k127_2725055_6	479434.Sthe_0650	4.256e-149	481.0	COG0372@1|root,COG0372@2|Bacteria,2G637@200795|Chloroflexi,27Y5Z@189775|Thermomicrobia	200795|Chloroflexi	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_2725055_16	479434.Sthe_0649	3.136e-25	106.0	COG0789@1|root,COG0789@2|Bacteria,2G9H2@200795|Chloroflexi,27Z9B@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
MMS3_k127_2725055_12	479434.Sthe_0648	6.485e-42	159.0	COG0745@1|root,COG0745@2|Bacteria	479434.Sthe_0648|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2725055_15	479434.Sthe_0647	6.439e-26	111.0	2A44J@1|root,30SPM@2|Bacteria,2GAIC@200795|Chloroflexi,27YM6@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2725055_13	309801.trd_0533	7.616e-40	150.0	COG0831@1|root,COG0831@2|Bacteria,2G73A@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
MMS3_k127_2725055_11	309801.trd_0532	8.425e-44	165.0	COG0832@1|root,COG0832@2|Bacteria,2G7HF@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
MMS3_k127_2725055_0	309801.trd_0531	1.606e-274	853.0	COG0804@1|root,COG0804@2|Bacteria,2G63F@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
MMS3_k127_2725055_9	266117.Rxyl_2556	2.085e-103	350.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria,4CT9Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Helix-turn-helix domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
MMS3_k127_2725055_7	316274.Haur_4146	1.584e-137	449.0	COG0372@1|root,COG0372@2|Bacteria,2G7NR@200795|Chloroflexi,3776D@32061|Chloroflexia	32061|Chloroflexia	H	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
MMS3_k127_2725055_10	309801.trd_0530	1.288e-92	308.0	COG3665@1|root,COG3665@2|Bacteria,2GB7V@200795|Chloroflexi,27XW9@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
MMS3_k127_2725055_5	479434.Sthe_0645	4.511e-166	527.0	COG0010@1|root,COG0010@2|Bacteria,2G71U@200795|Chloroflexi,27XNN@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_2725055_1	479434.Sthe_0644	2.531e-213	670.0	COG0304@1|root,COG0304@2|Bacteria,2G7RK@200795|Chloroflexi,27XNB@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMS3_k127_2725055_2	492774.JQMB01000016_gene1620	1.981e-200	630.0	COG4948@1|root,COG4948@2|Bacteria,1Q6XP@1224|Proteobacteria,2TVQ5@28211|Alphaproteobacteria,4B77P@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_2725055_8	1382356.JQMP01000001_gene969	3.679e-110	362.0	COG0451@1|root,COG0451@2|Bacteria,2G8UV@200795|Chloroflexi,27Z0H@189775|Thermomicrobia	189775|Thermomicrobia	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMS3_k127_2725055_3	1382356.JQMP01000001_gene964	5.696e-188	594.0	COG4948@1|root,COG4948@2|Bacteria,2G69R@200795|Chloroflexi,27YY3@189775|Thermomicrobia	189775|Thermomicrobia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_2725055_4	479434.Sthe_0642	1.284e-177	563.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,27XJW@189775|Thermomicrobia	189775|Thermomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
MMS3_k127_2725055_14	479434.Sthe_0641	9.142e-27	110.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
MMS3_k127_2725485_1	543728.Vapar_4526	9.696e-07	54.0	COG3843@1|root,COG3843@2|Bacteria,1MVHF@1224|Proteobacteria,2VS34@28216|Betaproteobacteria,4AIHZ@80864|Comamonadaceae	28216|Betaproteobacteria	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
MMS3_k127_2725485_0	622637.KE124774_gene447	1.695e-236	769.0	COG1061@1|root,COG1061@2|Bacteria,1QCQA@1224|Proteobacteria,2U1R6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1061 DNA or RNA helicases of superfamily II	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
MMS3_k127_2755891_5	43354.JOIJ01000012_gene934	3.336e-24	108.0	COG2142@1|root,COG2142@2|Bacteria	2|Bacteria	C	succinate dehydrogenase activity	-	-	-	ko:K00242,ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMS3_k127_2755891_4	1394178.AWOO02000006_gene3401	1.357e-35	142.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria,4EQ7D@85012|Streptosporangiales	201174|Actinobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMS3_k127_2755891_0	1394178.AWOO02000006_gene3402	3.998e-249	783.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4EGQW@85012|Streptosporangiales	201174|Actinobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_2755891_2	43354.JOIJ01000012_gene937	4.801e-89	301.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4DXT9@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1553	Fer2_3,Fer4_8
MMS3_k127_2755891_3	1394178.AWOO02000006_gene3394	2.165e-69	242.0	COG1838@1|root,COG1838@2|Bacteria,2GU98@201174|Actinobacteria	201174|Actinobacteria	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
MMS3_k127_2755891_1	1394178.AWOO02000006_gene3393	1.559e-124	407.0	COG1951@1|root,COG1951@2|Bacteria,2IGDQ@201174|Actinobacteria	201174|Actinobacteria	C	Tartrate dehydratase alpha subunit Fumarate hydratase class I N-terminal domain	ttdA	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
MMS3_k127_2764091_7	479434.Sthe_0459	2.474e-15	76.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi,27XJI@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_2764091_6	479434.Sthe_0458	2.666e-46	172.0	COG0328@1|root,COG0328@2|Bacteria,2GB0N@200795|Chloroflexi,27YNH@189775|Thermomicrobia	189775|Thermomicrobia	L	Reverse transcriptase-like	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
MMS3_k127_2764091_5	292459.STH1444	5.472e-52	188.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_2764091_0	266117.Rxyl_1300	3.958e-237	747.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CPK9@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
MMS3_k127_2764091_2	479434.Sthe_0455	3.436e-156	499.0	COG2355@1|root,COG2355@2|Bacteria,2G8C9@200795|Chloroflexi,27XYN@189775|Thermomicrobia	189775|Thermomicrobia	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMS3_k127_2764091_3	479434.Sthe_0447	2.774e-107	353.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi,27XQ2@189775|Thermomicrobia	189775|Thermomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2764091_4	479434.Sthe_0446	2.493e-96	322.0	COG0647@1|root,COG0647@2|Bacteria,2G6G5@200795|Chloroflexi,27XZJ@189775|Thermomicrobia	189775|Thermomicrobia	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
MMS3_k127_2764091_1	479434.Sthe_0445	2.053e-182	579.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,27XZ7@189775|Thermomicrobia	189775|Thermomicrobia	E	TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_2766572_0	479434.Sthe_0321	7.914e-107	351.0	COG0603@1|root,COG0603@2|Bacteria,2G8ZG@200795|Chloroflexi,27XHS@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
MMS3_k127_2766572_1	324602.Caur_2032	2.543e-41	164.0	COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi,375MG@32061|Chloroflexia	32061|Chloroflexia	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
MMS3_k127_2766572_2	479434.Sthe_0322	1.03e-11	69.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,27XGT@189775|Thermomicrobia	189775|Thermomicrobia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
MMS3_k127_276689_2	1382356.JQMP01000003_gene1318	2.033e-82	281.0	COG3836@1|root,COG3836@2|Bacteria,2G925@200795|Chloroflexi,27YE5@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
MMS3_k127_276689_0	479434.Sthe_0386	7.066e-150	479.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,27Y0I@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_276689_1	479434.Sthe_0387	3.709e-117	391.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XGK@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_2773562_3	479434.Sthe_1094	6.759e-24	104.0	2A4RF@1|root,30TCU@2|Bacteria,2GBBA@200795|Chloroflexi,27YN1@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2773562_0	479434.Sthe_1095	3.206e-272	852.0	COG0028@1|root,COG0028@2|Bacteria,2GBV7@200795|Chloroflexi,27XIE@189775|Thermomicrobia	189775|Thermomicrobia	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_2773562_1	479434.Sthe_1096	3.156e-104	347.0	COG2214@1|root,COG2214@2|Bacteria,2GA9M@200795|Chloroflexi,27YIW@189775|Thermomicrobia	189775|Thermomicrobia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2773562_2	1123023.JIAI01000003_gene2709	2.395e-54	198.0	COG2348@1|root,COG2348@2|Bacteria,2I7BS@201174|Actinobacteria,4E9SH@85010|Pseudonocardiales	201174|Actinobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
MMS3_k127_2786167_2	1230476.C207_02131	2.503e-51	194.0	COG0438@1|root,COG0438@2|Bacteria,1N2J8@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMS3_k127_2786167_0	479434.Sthe_1134	1.914e-189	600.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi,27XRP@189775|Thermomicrobia	2|Bacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	algD	-	1.1.1.132,1.1.1.22	ko:K00012,ko:K00066	ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020	M00014,M00129,M00361,M00362	R00286,R00880	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_2786167_1	697282.Mettu_3902	1.857e-119	396.0	COG0438@1|root,COG0438@2|Bacteria,1QTH7@1224|Proteobacteria,1RXHP@1236|Gammaproteobacteria,1XFTD@135618|Methylococcales	135618|Methylococcales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
MMS3_k127_2786167_3	698737.SLGD_02450	2.093e-05	56.0	COG1388@1|root,COG3942@1|root,COG1388@2|Bacteria,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4HIMT@91061|Bacilli,4GXJR@90964|Staphylococcaceae	91061|Bacilli	M	Peptidoglycan hydrolase involved in the splitting of the septum during cell division	sle1	-	3.5.1.28	ko:K22409	-	-	-	-	ko00000,ko01000	-	CBM50	-	CHAP,LysM
MMS3_k127_2802179_0	479434.Sthe_1596	1.357e-232	725.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi,27XKA@189775|Thermomicrobia	189775|Thermomicrobia	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
MMS3_k127_2802179_9	479434.Sthe_1597	1.093e-67	237.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi,27YDD@189775|Thermomicrobia	189775|Thermomicrobia	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
MMS3_k127_2802179_5	309801.trd_0690	1.203e-96	323.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi,27YCI@189775|Thermomicrobia	189775|Thermomicrobia	L	Bacterial dnaA  protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
MMS3_k127_2802179_8	479434.Sthe_1600	7.713e-70	263.0	COG0457@1|root,COG0457@2|Bacteria,2GAB1@200795|Chloroflexi,27Z9C@189775|Thermomicrobia	189775|Thermomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
MMS3_k127_2802179_1	479434.Sthe_1601	1.978e-129	420.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi,27XJ7@189775|Thermomicrobia	189775|Thermomicrobia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
MMS3_k127_2802179_4	309801.trd_0687	3.208e-98	336.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi,27YNP@189775|Thermomicrobia	189775|Thermomicrobia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
MMS3_k127_2802179_6	479434.Sthe_1603	4.318e-92	308.0	COG3707@1|root,COG3707@2|Bacteria,2G6CD@200795|Chloroflexi,27XQ5@189775|Thermomicrobia	189775|Thermomicrobia	T	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
MMS3_k127_2802179_11	479434.Sthe_1604	3.018e-51	184.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi,27YF7@189775|Thermomicrobia	189775|Thermomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
MMS3_k127_2802179_10	479434.Sthe_1605	1.31e-64	225.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi,27YC4@189775|Thermomicrobia	189775|Thermomicrobia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
MMS3_k127_2802179_2	479434.Sthe_1606	5.681e-117	381.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi,27XYK@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
MMS3_k127_2802179_7	479434.Sthe_1607	2.052e-75	254.0	COG0080@1|root,COG0080@2|Bacteria,2G6FF@200795|Chloroflexi,27Y72@189775|Thermomicrobia	189775|Thermomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
MMS3_k127_2802179_3	479434.Sthe_1608	1.586e-98	324.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,27XZ9@189775|Thermomicrobia	189775|Thermomicrobia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
MMS3_k127_2802179_14	479434.Sthe_1609	8.013e-21	98.0	COG0690@1|root,COG0690@2|Bacteria,2GBBW@200795|Chloroflexi,27YQ7@189775|Thermomicrobia	189775|Thermomicrobia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
MMS3_k127_2802179_15	661478.OP10G_0131	2.889e-07	53.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
MMS3_k127_2802179_12	479434.Sthe_1610	2.34e-25	106.0	COG0267@1|root,COG0267@2|Bacteria,2G7GT@200795|Chloroflexi,27ZAY@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
MMS3_k127_2802179_13	1304880.JAGB01000003_gene1212	1.103e-23	100.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMS3_k127_2805178_0	479434.Sthe_2691	0.0	1015.0	COG1523@1|root,COG1523@2|Bacteria,2G86B@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
MMS3_k127_2805178_2	526227.Mesil_1291	4.716e-138	453.0	COG0026@1|root,COG0026@2|Bacteria,1WITC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
MMS3_k127_2805178_4	309801.trd_0646	2.277e-76	259.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi,27YJ0@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
MMS3_k127_2805178_5	1541065.JRFE01000057_gene6269	6.28e-10	66.0	2DUIA@1|root,32UXB@2|Bacteria	2|Bacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
MMS3_k127_2805178_1	479434.Sthe_2106	5.992e-158	509.0	COG0438@1|root,COG0438@2|Bacteria,2G8D2@200795|Chloroflexi,27YUH@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
MMS3_k127_2805178_3	309801.trd_1095	1.305e-82	277.0	COG2159@1|root,COG2159@2|Bacteria,2G8UX@200795|Chloroflexi,27Z57@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
MMS3_k127_2818108_6	886293.Sinac_1018	1.062e-58	214.0	COG0500@1|root,COG0500@2|Bacteria,2J1HV@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_2818108_7	1382356.JQMP01000003_gene1753	2.593e-29	125.0	COG2261@1|root,COG2261@2|Bacteria,2GA9T@200795|Chloroflexi,27ZAS@189775|Thermomicrobia	189775|Thermomicrobia	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2818108_0	479434.Sthe_0335	1.894e-234	740.0	COG2340@1|root,COG2340@2|Bacteria,2G8G6@200795|Chloroflexi,27XTT@189775|Thermomicrobia	189775|Thermomicrobia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
MMS3_k127_2818108_5	479434.Sthe_0332	5.082e-59	213.0	COG0584@1|root,COG0584@2|Bacteria,2GA1A@200795|Chloroflexi,27YKV@189775|Thermomicrobia	189775|Thermomicrobia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
MMS3_k127_2818108_4	479434.Sthe_0331	1.475e-69	242.0	COG0671@1|root,COG0671@2|Bacteria,2G8YH@200795|Chloroflexi,27YK3@189775|Thermomicrobia	189775|Thermomicrobia	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
MMS3_k127_2818108_1	479434.Sthe_0330	5.981e-152	486.0	COG0761@1|root,COG0761@2|Bacteria,2G75Z@200795|Chloroflexi,27Y0F@189775|Thermomicrobia	189775|Thermomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
MMS3_k127_2818108_3	479434.Sthe_0328	4.863e-78	268.0	COG1011@1|root,COG1011@2|Bacteria,2G73G@200795|Chloroflexi,27YDM@189775|Thermomicrobia	189775|Thermomicrobia	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
MMS3_k127_2818108_2	479434.Sthe_0324	6.942e-98	326.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,27XJ1@189775|Thermomicrobia	189775|Thermomicrobia	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
MMS3_k127_2824339_5	309801.trd_1360	3.958e-37	146.0	COG2353@1|root,COG2353@2|Bacteria,2G6G9@200795|Chloroflexi,27Y8W@189775|Thermomicrobia	189775|Thermomicrobia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
MMS3_k127_2824339_0	42256.RradSPS_2521	7.713e-161	519.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4CS6S@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_2824339_1	479434.Sthe_2593	2.958e-118	400.0	COG1834@1|root,COG1834@2|Bacteria,2G7QT@200795|Chloroflexi,27YZU@189775|Thermomicrobia	189775|Thermomicrobia	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
MMS3_k127_2824339_4	1449976.KALB_8332	2.125e-86	292.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4E1TR@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_2824339_3	351607.Acel_1448	9.605e-89	311.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2GIV9@201174|Actinobacteria,4EXEH@85013|Frankiales	201174|Actinobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_2824339_2	525904.Tter_2847	1.996e-101	340.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
MMS3_k127_2824339_6	479434.Sthe_1129	9.949e-26	110.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27Z0Q@189775|Thermomicrobia	189775|Thermomicrobia	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_283143_0	479434.Sthe_2649	4.278e-304	944.0	COG0465@1|root,COG0465@2|Bacteria,2G63X@200795|Chloroflexi,27XYF@189775|Thermomicrobia	189775|Thermomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_283143_1	479434.Sthe_2648	2.955e-94	316.0	COG0006@1|root,COG0006@2|Bacteria,2G6AH@200795|Chloroflexi	2|Bacteria	E	peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_2837431_3	479434.Sthe_1115	4.408e-107	351.0	COG2204@1|root,COG2204@2|Bacteria,2G5ZP@200795|Chloroflexi	200795|Chloroflexi	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMS3_k127_2837431_1	479434.Sthe_1116	7.975e-180	579.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi,27XTZ@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
MMS3_k127_2837431_0	479434.Sthe_1121	3.628e-212	665.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi,27XWS@189775|Thermomicrobia	189775|Thermomicrobia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMS3_k127_2837431_2	479434.Sthe_1122	1.479e-162	516.0	COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi,27XYP@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
MMS3_k127_2839121_6	743299.Acife_3096	3.654e-27	122.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,1T7WD@1236|Gammaproteobacteria,2NBZU@225057|Acidithiobacillales	225057|Acidithiobacillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_2839121_8	309801.trd_A0181	2.006e-26	117.0	COG1873@1|root,COG3798@1|root,COG1873@2|Bacteria,COG3798@2|Bacteria	2|Bacteria	O	Protein conserved in bacteria	MA20_37705	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,DUF2171,MgtE_N,PRC
MMS3_k127_2839121_9	552531.BIF_01957	0.0003129	47.0	COG2261@1|root,COG2261@2|Bacteria,2GSMF@201174|Actinobacteria,4D1J1@85004|Bifidobacteriales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
MMS3_k127_2839121_2	1123060.JONP01000024_gene2500	6.295e-163	531.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase B acetone carboxylase alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydantoinase_B
MMS3_k127_2839121_1	479434.Sthe_2889	1.751e-226	722.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	2|Bacteria	EQ	Hydantoinaseoxoprolinase domain protein	oplaH	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
MMS3_k127_2839121_4	1192034.CAP_7606	2.519e-49	182.0	COG0537@1|root,COG0537@2|Bacteria,1PDTP@1224|Proteobacteria,42UAD@68525|delta/epsilon subdivisions,2WQRN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
MMS3_k127_2839121_3	450851.PHZ_p0133	2.341e-130	424.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria	1224|Proteobacteria	C	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMS3_k127_2839121_0	450851.PHZ_p0134	0.0	1907.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,2U2F7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
MMS3_k127_2839121_5	450851.PHZ_p0135	2.422e-32	125.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria,2KJRT@204458|Caulobacterales	28211|Alphaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2,Pyr_redox_3
MMS3_k127_2842779_10	479434.Sthe_0795	1.149e-65	231.0	2BQJQ@1|root,32JFR@2|Bacteria,2GA0E@200795|Chloroflexi,27YBB@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2842779_1	479434.Sthe_0794	1.9e-231	728.0	COG3858@1|root,COG3858@2|Bacteria,2G7HP@200795|Chloroflexi,27XZM@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycoside hydrolase, family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
MMS3_k127_2842779_12	479434.Sthe_0793	6.392e-59	214.0	COG0757@1|root,COG0757@2|Bacteria,2G70K@200795|Chloroflexi,27YDC@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
MMS3_k127_2842779_5	479434.Sthe_0792	4.072e-147	473.0	COG0006@1|root,COG0006@2|Bacteria,2G6AE@200795|Chloroflexi,27XYM@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_2842779_9	479434.Sthe_0791	5.083e-89	297.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi,27Y78@189775|Thermomicrobia	189775|Thermomicrobia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
MMS3_k127_2842779_13	479434.Sthe_0790	5.677e-43	162.0	COG0511@1|root,COG0511@2|Bacteria,2G94M@200795|Chloroflexi,27YJ8@189775|Thermomicrobia	189775|Thermomicrobia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
MMS3_k127_2842779_4	479434.Sthe_0789	2.658e-162	521.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi,27XEW@189775|Thermomicrobia	189775|Thermomicrobia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
MMS3_k127_2842779_17	479434.Sthe_0788	5.541e-14	75.0	COG1722@1|root,COG1722@2|Bacteria,2G9U8@200795|Chloroflexi,27YQ2@189775|Thermomicrobia	189775|Thermomicrobia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
MMS3_k127_2842779_0	479434.Sthe_2668	0.0	1403.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_2842779_15	479434.Sthe_0786	1.148e-38	147.0	COG0537@1|root,COG0537@2|Bacteria,2G6VV@200795|Chloroflexi,27YE1@189775|Thermomicrobia	189775|Thermomicrobia	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
MMS3_k127_2842779_7	479434.Sthe_0785	4.701e-111	364.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi,27YBP@189775|Thermomicrobia	189775|Thermomicrobia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
MMS3_k127_2842779_2	479434.Sthe_0784	8.509e-202	634.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi,27Y4R@189775|Thermomicrobia	189775|Thermomicrobia	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_2842779_3	479434.Sthe_1625	4.786e-181	576.0	COG2843@1|root,COG2843@2|Bacteria,2G9WJ@200795|Chloroflexi,27YSA@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
MMS3_k127_2842779_20	1157637.KB892103_gene1683	8.272e-05	52.0	COG0498@1|root,COG0498@2|Bacteria,2GNZD@201174|Actinobacteria	201174|Actinobacteria	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_2842779_11	479434.Sthe_3201	4.213e-63	230.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad,Tad_C
MMS3_k127_2842779_16	247639.MGP2080_02001	1.255e-19	98.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15,2.7.13.3	ko:K03564,ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AhpC-TSA
MMS3_k127_2842779_6	28444.JODQ01000014_gene6850	1.013e-114	399.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EMPS@85012|Streptosporangiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_2842779_8	479434.Sthe_3071	2.145e-107	356.0	COG2141@1|root,COG2141@2|Bacteria,2G8CA@200795|Chloroflexi,27Y7R@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2847082_2	479434.Sthe_2346	9.971e-50	182.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
MMS3_k127_2847082_0	298654.FraEuI1c_1520	1.22e-61	229.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4ETZT@85013|Frankiales	201174|Actinobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_2847082_3	479434.Sthe_2397	5.041e-33	133.0	COG0748@1|root,COG0748@2|Bacteria	2|Bacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_285042_3	1227487.C474_04510	4.73e-171	555.0	COG2146@1|root,arCOG02852@2157|Archaea,2XUZH@28890|Euryarchaeota,23SZ3@183963|Halobacteria	183963|Halobacteria	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
MMS3_k127_285042_18	525904.Tter_2161	4.698e-14	74.0	2F19C@1|root,33UAD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_285042_5	479434.Sthe_0251	5.13e-133	429.0	COG3885@1|root,COG3885@2|Bacteria,2GB8J@200795|Chloroflexi,27Y2B@189775|Thermomicrobia	189775|Thermomicrobia	C	PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B	-	-	-	-	-	-	-	-	-	-	-	-	LigB
MMS3_k127_285042_1	1122921.KB898187_gene4451	5.854e-213	681.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,26TYG@186822|Paenibacillaceae	91061|Bacilli	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_285042_0	1173024.KI912148_gene4415	1.016e-222	710.0	COG2366@1|root,COG2366@2|Bacteria,1G0QT@1117|Cyanobacteria,1JK3D@1189|Stigonemataceae	1117|Cyanobacteria	S	Penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
MMS3_k127_285042_2	1122921.KB898187_gene4452	8.491e-200	644.0	COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,4HBKB@91061|Bacilli,26V39@186822|Paenibacillaceae	91061|Bacilli	EQ	COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_285042_19	1250232.JQNJ01000001_gene2498	5.755e-10	66.0	2DZVD@1|root,32VJZ@2|Bacteria,4NUB2@976|Bacteroidetes,1I482@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
MMS3_k127_285042_17	616991.JPOO01000003_gene419	7.686e-20	94.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1I4HD@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
MMS3_k127_285042_4	383372.Rcas_0520	4.718e-136	444.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_285042_12	525904.Tter_1882	5.436e-87	299.0	COG0673@1|root,COG0673@2|Bacteria,2NRE6@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_285042_7	1445613.JALM01000067_gene5556	4.526e-111	373.0	COG1921@1|root,COG1921@2|Bacteria,2GNZX@201174|Actinobacteria,4E6BX@85010|Pseudonocardiales	201174|Actinobacteria	E	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
MMS3_k127_285042_9	485913.Krac_9258	3.887e-97	320.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
MMS3_k127_285042_13	404589.Anae109_1054	7.674e-84	287.0	COG1018@1|root,COG1018@2|Bacteria,1R5FN@1224|Proteobacteria	1224|Proteobacteria	C	Oxidoreductase FAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
MMS3_k127_285042_15	246197.MXAN_5223	5.503e-63	219.0	COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria,42ZTP@68525|delta/epsilon subdivisions,2WV97@28221|Deltaproteobacteria,2YWVF@29|Myxococcales	28221|Deltaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_285042_16	1120950.KB892823_gene495	7.061e-42	159.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4DRIQ@85009|Propionibacteriales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
MMS3_k127_285042_6	215803.DB30_8806	5.71e-115	389.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria,2YWK1@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_285042_10	926561.KB900620_gene2917	1.971e-94	320.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WB1B@53433|Halanaerobiales	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
MMS3_k127_285042_11	479434.Sthe_3428	2.779e-93	315.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi,27XFE@189775|Thermomicrobia	2|Bacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_285042_8	1054213.HMPREF9946_00347	2.806e-99	347.0	COG0747@1|root,COG0747@2|Bacteria,1P1HT@1224|Proteobacteria,2U18T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
MMS3_k127_285042_21	455632.SGR_4606	5.221e-06	56.0	COG0640@1|root,COG0640@2|Bacteria,2IQKG@201174|Actinobacteria,41APK@629295|Streptomyces griseus group	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_285042_14	479434.Sthe_2019	2.565e-83	288.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi,27Y6A@189775|Thermomicrobia	189775|Thermomicrobia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_2870644_2	1463895.JODA01000001_gene385	6.819e-18	90.0	COG4758@1|root,COG4758@2|Bacteria,2GMRP@201174|Actinobacteria	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
MMS3_k127_2870644_0	1347369.CCAD010000065_gene3831	2.266e-64	231.0	COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,1ZC41@1386|Bacillus	91061|Bacilli	E	D-aminopeptidase	dppA	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	iYO844.BSU12920	Peptidase_M55
MMS3_k127_2870644_1	479434.Sthe_3483	5.234e-32	125.0	COG3653@1|root,COG3653@2|Bacteria,2G5ZI@200795|Chloroflexi,27XTY@189775|Thermomicrobia	189775|Thermomicrobia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_2882588_6	927677.ALVU02000004_gene4738	4.978e-98	336.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,DUF4062,NB-ARC,TPR_12
MMS3_k127_2882588_5	479434.Sthe_1741	2.014e-129	426.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K19223	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
MMS3_k127_2882588_1	479434.Sthe_3483	7.57e-267	830.0	COG3653@1|root,COG3653@2|Bacteria,2G5ZI@200795|Chloroflexi,27XTY@189775|Thermomicrobia	189775|Thermomicrobia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_2882588_3	525904.Tter_2307	3.079e-152	493.0	COG3004@1|root,COG3004@2|Bacteria,2NNWA@2323|unclassified Bacteria	2|Bacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
MMS3_k127_2882588_4	479434.Sthe_3430	3.388e-133	438.0	COG1680@1|root,COG1680@2|Bacteria,2G6QM@200795|Chloroflexi,27XFJ@189775|Thermomicrobia	189775|Thermomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_2882588_0	479434.Sthe_3483	1.734e-281	872.0	COG3653@1|root,COG3653@2|Bacteria,2G5ZI@200795|Chloroflexi,27XTY@189775|Thermomicrobia	189775|Thermomicrobia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_2882588_2	479434.Sthe_3483	1.621e-153	492.0	COG3653@1|root,COG3653@2|Bacteria,2G5ZI@200795|Chloroflexi,27XTY@189775|Thermomicrobia	189775|Thermomicrobia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_2890489_5	479434.Sthe_3451	1.292e-19	91.0	COG4464@1|root,COG4464@2|Bacteria,2G94G@200795|Chloroflexi,27YE0@189775|Thermomicrobia	189775|Thermomicrobia	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
MMS3_k127_2890489_6	335543.Sfum_1832	5.411e-12	72.0	2EHG8@1|root,33B84@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_2890489_3	1232410.KI421428_gene1178	6.873e-57	209.0	COG0596@1|root,COG0596@2|Bacteria,1RGAP@1224|Proteobacteria,42XWU@68525|delta/epsilon subdivisions,2WSMY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_2890489_2	272630.MexAM1_META1p0224	4.277e-61	218.0	COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2U6E4@28211|Alphaproteobacteria,1JSFC@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	PFAM OsmC family protein	MA20_23315	-	-	-	-	-	-	-	-	-	-	-	OsmC
MMS3_k127_2890489_1	1122917.KB899667_gene3708	6.534e-87	300.0	COG2159@1|root,COG2159@2|Bacteria,1UZAH@1239|Firmicutes,4HA5S@91061|Bacilli,26SJA@186822|Paenibacillaceae	91061|Bacilli	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
MMS3_k127_2890489_4	797209.ZOD2009_21082	3.983e-39	150.0	COG2146@1|root,arCOG02852@2157|Archaea,2XYID@28890|Euryarchaeota,23WE2@183963|Halobacteria	183963|Halobacteria	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
MMS3_k127_2890489_0	309801.trd_A0407	6.393e-94	321.0	COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi,27XRM@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
MMS3_k127_2891825_1	485913.Krac_11339	9.633e-24	113.0	2FEK6@1|root,346JM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2891825_0	479434.Sthe_2350	2.274e-74	280.0	COG0823@1|root,COG0823@2|Bacteria,2GBFZ@200795|Chloroflexi,27ZCM@189775|Thermomicrobia	189775|Thermomicrobia	U	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2893286_17	479434.Sthe_2125	1.381e-41	156.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27YYN@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMS3_k127_2893286_3	479434.Sthe_2124	5.786e-137	453.0	2DTHQ@1|root,33KDI@2|Bacteria,2G7BU@200795|Chloroflexi,27Z1X@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
MMS3_k127_2893286_2	479434.Sthe_2394	2.674e-168	537.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi,27XYQ@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
MMS3_k127_2893286_13	1242864.D187_009928	7.954e-58	229.0	COG3437@1|root,COG3437@2|Bacteria,1RGGM@1224|Proteobacteria,42RTT@68525|delta/epsilon subdivisions,2WNA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
MMS3_k127_2893286_11	555079.Toce_1910	1.775e-63	227.0	COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,24CY1@186801|Clostridia,42GKA@68295|Thermoanaerobacterales	186801|Clostridia	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
MMS3_k127_2893286_1	479434.Sthe_2688	9.982e-190	597.0	COG2355@1|root,COG2355@2|Bacteria,2G8C9@200795|Chloroflexi,27XYN@189775|Thermomicrobia	200795|Chloroflexi	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
MMS3_k127_2893286_5	1265505.ATUG01000001_gene3026	1.618e-110	382.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
MMS3_k127_2893286_15	1385519.N801_16225	4.507e-52	194.0	COG1266@1|root,COG1266@2|Bacteria,2IGUR@201174|Actinobacteria,4FJ7Y@85021|Intrasporangiaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
MMS3_k127_2893286_23	586413.CCDL010000001_gene1418	2.182e-05	49.0	29TPQ@1|root,30EXR@2|Bacteria,1UD42@1239|Firmicutes,4IDUW@91061|Bacilli,23N73@182709|Oceanobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2893286_4	345341.KUTG_02428	1.869e-133	437.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DZ0A@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
MMS3_k127_2893286_8	1123023.JIAI01000007_gene2018	2.042e-99	332.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2893286_12	1082933.MEA186_18762	1.126e-61	215.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,2U9TG@28211|Alphaproteobacteria,43MEK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_2893286_14	1206737.BAGF01000062_gene4155	2.287e-56	203.0	COG5646@1|root,COG5646@2|Bacteria,2IINN@201174|Actinobacteria,4G0JA@85025|Nocardiaceae	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
MMS3_k127_2893286_0	253839.SSNG_00405	0.0	1167.0	COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria	201174|Actinobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
MMS3_k127_2893286_18	1382306.JNIM01000001_gene4040	5.775e-27	124.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi	200795|Chloroflexi	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
MMS3_k127_2893286_19	713586.KB900536_gene2760	7.533e-17	95.0	COG2010@1|root,COG2010@2|Bacteria,1RG2C@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome c	-	-	-	ko:K00405,ko:K07245	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko02000	3.D.4.3,9.B.62.1	-	-	AhpC-TSA,CopD,Cytochrome_CBB3
MMS3_k127_2893286_10	1382356.JQMP01000003_gene1491	7.913e-76	281.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2G8KM@200795|Chloroflexi	2|Bacteria	P	PFAM copper resistance protein CopC	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07156,ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1,9.B.62.2	-	-	CopC,CopD,YtkA
MMS3_k127_2893286_16	1382356.JQMP01000003_gene1492	6.609e-46	174.0	arCOG08811@1|root,32UTS@2|Bacteria,2G8VM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2893286_6	1502851.FG93_03415	1.016e-103	347.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,3JRP5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	MA20_37085	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
MMS3_k127_2893286_9	56107.Cylst_2613	1.976e-78	279.0	COG1520@1|root,COG1520@2|Bacteria,1GDEQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
MMS3_k127_2893286_7	266117.Rxyl_2946	1.023e-102	357.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
MMS3_k127_289429_3	479434.Sthe_3485	2.232e-49	177.0	COG1239@1|root,COG1239@2|Bacteria,2GB7G@200795|Chloroflexi,27XRK@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
MMS3_k127_289429_0	479434.Sthe_3486	0.0	1118.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_289429_6	479434.Sthe_3487	2.917e-19	93.0	2A4RF@1|root,30YTM@2|Bacteria,2GA1K@200795|Chloroflexi,27YN9@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_289429_1	479434.Sthe_3492	8.15e-123	398.0	COG0095@1|root,COG0095@2|Bacteria,2G7JY@200795|Chloroflexi,27XM5@189775|Thermomicrobia	189775|Thermomicrobia	H	biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
MMS3_k127_289429_5	1247649.D560_3443	9.019e-29	117.0	COG0095@1|root,COG0095@2|Bacteria,1P0IW@1224|Proteobacteria,2W4CK@28216|Betaproteobacteria,3T4TG@506|Alcaligenaceae	28216|Betaproteobacteria	H	Lipoate-protein ligase A	-	-	-	-	-	-	-	-	-	-	-	-	Lip_prot_lig_C
MMS3_k127_289429_2	485913.Krac_4181	1.601e-74	261.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,F420_oxidored,NAD_binding_2
MMS3_k127_289429_4	1356854.N007_15535	1.407e-38	151.0	COG0684@1|root,COG0684@2|Bacteria,1W795@1239|Firmicutes,4HSY7@91061|Bacilli,27AKQ@186823|Alicyclobacillaceae	91061|Bacilli	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
MMS3_k127_2894422_0	479434.Sthe_0666	2.317e-171	552.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	2|Bacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_2894422_2	479434.Sthe_2313	4.374e-84	296.0	COG0665@1|root,COG0665@2|Bacteria,2G6QE@200795|Chloroflexi,27Y6M@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_2894422_6	65393.PCC7424_0625	3.345e-32	146.0	COG0631@1|root,COG0631@2|Bacteria,1G2FY@1117|Cyanobacteria,3KGT7@43988|Cyanothece	1117|Cyanobacteria	T	SMART protein phosphatase 2C domain protein	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
MMS3_k127_2894422_3	926569.ANT_23640	1.423e-78	292.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
MMS3_k127_2894422_5	357808.RoseRS_0666	4.974e-57	224.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
MMS3_k127_2894422_1	1370125.AUWT01000032_gene1634	1.54e-105	351.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
MMS3_k127_2894422_4	1370125.AUWT01000032_gene1633	1.028e-67	244.0	COG2203@1|root,COG2203@2|Bacteria,2I97I@201174|Actinobacteria	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
MMS3_k127_2894422_7	1526927.Plano_0099	1.227e-10	70.0	COG2114@1|root,COG2114@2|Bacteria,1V8X9@1239|Firmicutes,4IQCE@91061|Bacilli,26GPU@186818|Planococcaceae	91061|Bacilli	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
MMS3_k127_2894956_6	479434.Sthe_3454	4.66e-05	52.0	COG0451@1|root,COG0451@2|Bacteria,2G74B@200795|Chloroflexi	200795|Chloroflexi	GM	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
MMS3_k127_2894956_4	1172188.KB911825_gene3574	1.733e-53	210.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4FFZV@85021|Intrasporangiaceae	201174|Actinobacteria	DM	biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	ParA,Wzz
MMS3_k127_2894956_3	479434.Sthe_1142	1.943e-72	253.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
MMS3_k127_2894956_1	479434.Sthe_1141	7.615e-140	453.0	COG0673@1|root,COG0673@2|Bacteria,2G6PI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_2894956_0	479434.Sthe_1140	8.452e-149	480.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMS3_k127_2894956_5	706587.Desti_0945	3.114e-28	131.0	COG3307@1|root,COG3307@2|Bacteria,1NGAP@1224|Proteobacteria	1224|Proteobacteria	M	O-Antigen Polymerase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
MMS3_k127_2894956_2	479434.Sthe_1138	6.625e-104	354.0	COG2244@1|root,COG2244@2|Bacteria,2G8GU@200795|Chloroflexi	200795|Chloroflexi	S	virulence factor MVIN family protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
MMS3_k127_2906403_8	272558.10174506	1.162e-65	230.0	COG2320@1|root,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,4HH5X@91061|Bacilli,1ZHJE@1386|Bacillus	91061|Bacilli	K	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
MMS3_k127_2906403_4	1111479.AXAR01000008_gene2274	1.448e-107	366.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,4HDDP@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
MMS3_k127_2906403_5	1122927.KB895413_gene1857	9.191e-97	321.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HDUW@91061|Bacilli,26VPT@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	-	-	-	ko:K18349	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_2906403_16	479434.Sthe_0183	1.912e-07	55.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
MMS3_k127_2906403_6	469383.Cwoe_4858	4.414e-96	320.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_2906403_0	1394178.AWOO02000061_gene5969	1.882e-203	661.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4EG0F@85012|Streptosporangiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_2906403_1	102125.Xen7305DRAFT_00020800	3.216e-191	613.0	COG2303@1|root,COG2303@2|Bacteria,1G0XW@1117|Cyanobacteria,3VN49@52604|Pleurocapsales	1117|Cyanobacteria	E	COGs COG2303 Choline dehydrogenase and related flavoprotein	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
MMS3_k127_2906403_7	266117.Rxyl_1041	1.366e-73	252.0	COG1670@1|root,COG1670@2|Bacteria,2HP6V@201174|Actinobacteria,4CTRA@84995|Rubrobacteria	84995|Rubrobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_2906403_10	749927.AMED_7935	6.795e-37	147.0	COG0500@1|root,COG2226@2|Bacteria,2IPTP@201174|Actinobacteria,4EAQM@85010|Pseudonocardiales	201174|Actinobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_2906403_3	1380386.JIAW01000005_gene1440	4.241e-120	390.0	COG4312@1|root,COG4312@2|Bacteria,2GN8A@201174|Actinobacteria,235YI@1762|Mycobacteriaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
MMS3_k127_2906403_15	1068980.ARVW01000001_gene5690	3.585e-08	59.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria,4DY8V@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
MMS3_k127_2906403_11	1120971.AUCA01000025_gene781	1.496e-25	123.0	2DGGT@1|root,2ZVX8@2|Bacteria,1V6AM@1239|Firmicutes,4HVWB@91061|Bacilli	91061|Bacilli	S	Peptidase A4 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A4
MMS3_k127_2906403_13	634956.Geoth_0267	2.465e-24	107.0	COG3564@1|root,COG3564@2|Bacteria,1V81N@1239|Firmicutes,4HIP2@91061|Bacilli,1WGH4@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function (DUF779)	-	-	-	ko:K09959	-	-	-	-	ko00000	-	-	-	DUF779
MMS3_k127_2906403_12	1894.JOER01000084_gene1584	2.227e-24	118.0	2DGGT@1|root,2ZVX8@2|Bacteria,2I9A3@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase A4 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A4
MMS3_k127_2906403_2	525904.Tter_0222	8.897e-129	422.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	rip3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
MMS3_k127_2906403_9	1122182.KB903814_gene3095	6.005e-41	158.0	COG0494@1|root,COG0494@2|Bacteria,2IKMP@201174|Actinobacteria	201174|Actinobacteria	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
MMS3_k127_2906403_14	485913.Krac_4790	5.769e-16	79.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_2908019_1	479434.Sthe_2141	2.084e-12	67.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	200795|Chloroflexi	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
MMS3_k127_2908019_0	479434.Sthe_1357	7.527e-281	875.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,27YSI@189775|Thermomicrobia	189775|Thermomicrobia	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_2934304_0	1267535.KB906767_gene3657	1.381e-30	131.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Anp1,Gly_transf_sug,Glycos_transf_2,Glyphos_transf
MMS3_k127_2934304_1	1123258.AQXZ01000013_gene1980	5.504e-06	54.0	COG1225@1|root,COG2259@1|root,COG1225@2|Bacteria,COG2259@2|Bacteria,2ICCJ@201174|Actinobacteria,4FZRI@85025|Nocardiaceae	201174|Actinobacteria	O	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,MauE
MMS3_k127_2936533_5	591159.ACEZ01000091_gene7140	5.797e-10	60.0	COG1426@1|root,COG1426@2|Bacteria,2I4Y1@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,HTH_37
MMS3_k127_2936533_4	762376.AXYL_05067	1.153e-67	240.0	COG3386@1|root,COG3386@2|Bacteria,1QN8Y@1224|Proteobacteria,2VQIM@28216|Betaproteobacteria	28216|Betaproteobacteria	G	SMP-30 Gluconolaconase LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
MMS3_k127_2936533_1	1416752.AYME01000005_gene1756	1.477e-162	524.0	COG2133@1|root,COG2133@2|Bacteria,2IASI@201174|Actinobacteria,4FMWN@85023|Microbacteriaceae	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2936533_0	1397278.AYMV01000001_gene464	3.355e-200	638.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4FQUW@85023|Microbacteriaceae	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMS3_k127_2936533_3	1452536.JARE01000030_gene1074	5.563e-80	275.0	COG1173@1|root,COG1173@2|Bacteria,2IAGE@201174|Actinobacteria	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_2936533_2	469383.Cwoe_0113	2.731e-86	291.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4CSMS@84995|Rubrobacteria	84995|Rubrobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
MMS3_k127_2944017_14	1382356.JQMP01000004_gene152	4.453e-39	167.0	COG0823@1|root,COG0823@2|Bacteria,2GBHT@200795|Chloroflexi,27XYS@189775|Thermomicrobia	189775|Thermomicrobia	U	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PD40
MMS3_k127_2944017_6	521011.Mpal_0423	6.905e-100	352.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
MMS3_k127_2944017_7	309801.trd_A0730	1.377e-91	327.0	COG1525@1|root,COG1525@2|Bacteria,2GBHE@200795|Chloroflexi,27YTT@189775|Thermomicrobia	189775|Thermomicrobia	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2944017_11	525904.Tter_1053	6.929e-56	204.0	COG0586@1|root,COG0586@2|Bacteria,2NPJ6@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_2944017_10	485913.Krac_10280	2.791e-60	218.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi	2|Bacteria	S	PFAM alpha beta hydrolase fold	MA20_20400	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_2944017_0	326427.Cagg_2657	3.263e-230	720.0	COG0174@1|root,COG0174@2|Bacteria,2G5U2@200795|Chloroflexi,3751E@32061|Chloroflexia	32061|Chloroflexia	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
MMS3_k127_2944017_12	383372.Rcas_1915	7.811e-42	160.0	COG1595@1|root,COG1595@2|Bacteria,2GB53@200795|Chloroflexi,377AG@32061|Chloroflexia	32061|Chloroflexia	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_2944017_8	345341.KUTG_03449	1.438e-72	252.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4E3H9@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
MMS3_k127_2944017_16	1122132.AQYH01000006_gene3502	0.0001693	52.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,4BAIQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
MMS3_k127_2944017_5	1104324.P186_2108	5.242e-106	356.0	COG0535@1|root,arCOG00940@2157|Archaea,2XSRZ@28889|Crenarchaeota	28889|Crenarchaeota	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
MMS3_k127_2944017_9	309801.trd_A0395	9.304e-69	245.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
MMS3_k127_2944017_13	309801.trd_A0674	2.803e-39	164.0	2DP6G@1|root,330R3@2|Bacteria,2G93U@200795|Chloroflexi,27YFD@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
MMS3_k127_2944017_1	479434.Sthe_3135	1.283e-177	565.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27Y3Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMS3_k127_2944017_2	479434.Sthe_3134	8.898e-156	500.0	COG0714@1|root,COG0714@2|Bacteria,2GANG@200795|Chloroflexi,27Y4P@189775|Thermomicrobia	189775|Thermomicrobia	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
MMS3_k127_2944017_3	525904.Tter_0420	3.553e-121	396.0	COG1173@1|root,COG1173@2|Bacteria,2NQ14@2323|unclassified Bacteria	2|Bacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
MMS3_k127_2944017_4	525904.Tter_0419	3.731e-119	390.0	COG0601@1|root,COG0601@2|Bacteria,2NQCD@2323|unclassified Bacteria	2|Bacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
MMS3_k127_2945160_1	891968.Anamo_1936	2.569e-05	47.0	COG3535@1|root,COG3535@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
MMS3_k127_2945160_0	589924.Ferp_0995	1.588e-196	629.0	COG0209@1|root,arCOG04276@2157|Archaea,2XUBW@28890|Euryarchaeota,245VM@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
MMS3_k127_2949348_5	1382356.JQMP01000003_gene1423	7.08e-107	361.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
MMS3_k127_2949348_6	479434.Sthe_2032	9.662e-106	349.0	COG2367@1|root,COG2367@2|Bacteria,2GBEG@200795|Chloroflexi,27Z5G@189775|Thermomicrobia	189775|Thermomicrobia	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMS3_k127_2949348_3	479434.Sthe_2030	2.469e-126	409.0	COG2362@1|root,COG2362@2|Bacteria,2G8M4@200795|Chloroflexi,27Z3T@189775|Thermomicrobia	189775|Thermomicrobia	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
MMS3_k127_2949348_0	1382356.JQMP01000003_gene1838	2.1e-198	634.0	COG0318@1|root,COG0318@2|Bacteria,2G5XA@200795|Chloroflexi,27YWU@189775|Thermomicrobia	189775|Thermomicrobia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_2949348_2	1382356.JQMP01000003_gene1484	1.048e-174	553.0	COG0473@1|root,COG0473@2|Bacteria,2G8A7@200795|Chloroflexi,27XIB@189775|Thermomicrobia	189775|Thermomicrobia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
MMS3_k127_2949348_1	479434.Sthe_0187	7.278e-182	577.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	allC	GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009442,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0017144,GO:0030145,GO:0034641,GO:0042737,GO:0043167,GO:0043169,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047652,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iECH74115_1262.ECH74115_0617,iECSP_1301.ECSP_0590,iECUMN_1333.ECUMN_0556,iECs_1301.ECs0578,iZ_1308.Z0671	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_2949348_7	469383.Cwoe_0966	1.942e-77	268.0	COG0842@1|root,COG0842@2|Bacteria,2HG4S@201174|Actinobacteria,4CQ73@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_2949348_4	1463856.JOHY01000008_gene934	2.804e-113	377.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_2949348_8	479434.Sthe_0432	1.143e-56	206.0	COG1695@1|root,COG1695@2|Bacteria,2G9FP@200795|Chloroflexi	200795|Chloroflexi	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_2949348_9	479434.Sthe_1677	7.072e-13	76.0	COG1309@1|root,COG1309@2|Bacteria,2G8XR@200795|Chloroflexi,27Z5B@189775|Thermomicrobia	189775|Thermomicrobia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_2955945_4	479434.Sthe_2464	3.939e-111	364.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi,27Y51@189775|Thermomicrobia	189775|Thermomicrobia	D	Anion-transporting ATPase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMS3_k127_2955945_1	479434.Sthe_2465	8.588e-258	804.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi,27XW4@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
MMS3_k127_2955945_7	1382356.JQMP01000003_gene1641	3.086e-54	194.0	COG0071@1|root,COG0071@2|Bacteria,2GBA5@200795|Chloroflexi,27YFK@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_2955945_3	479434.Sthe_2316	9.795e-140	452.0	COG2141@1|root,COG2141@2|Bacteria,2G9ZI@200795|Chloroflexi,27XUK@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_2955945_2	479434.Sthe_2317	2.113e-193	613.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,27YVX@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
MMS3_k127_2955945_5	1382356.JQMP01000003_gene1756	1.994e-80	278.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi,27YZ7@189775|Thermomicrobia	189775|Thermomicrobia	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
MMS3_k127_2955945_0	479434.Sthe_2025	0.0	1041.0	COG0365@1|root,COG0365@2|Bacteria,2G83G@200795|Chloroflexi,27XZN@189775|Thermomicrobia	189775|Thermomicrobia	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMS3_k127_2955945_6	555079.Toce_0327	2.717e-76	270.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,42FJJ@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMS3_k127_2962059_0	479434.Sthe_0441	0.0	1372.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMS3_k127_2962059_1	479434.Sthe_0440	4.335e-47	172.0	COG0789@1|root,COG0789@2|Bacteria,2G72X@200795|Chloroflexi,27YHN@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
MMS3_k127_2962059_2	479434.Sthe_0439	2.129e-28	119.0	COG1686@1|root,COG1686@2|Bacteria,2G8TU@200795|Chloroflexi,27XVX@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
MMS3_k127_2982000_9	1382356.JQMP01000004_gene615	2.493e-25	108.0	COG3535@1|root,COG3535@2|Bacteria,2GA3G@200795|Chloroflexi,27Z08@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
MMS3_k127_2982000_3	264732.Moth_0211	1.597e-134	434.0	arCOG05881@1|root,2Z800@2|Bacteria,1TS9C@1239|Firmicutes,24CDW@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1177
MMS3_k127_2982000_5	1487953.JMKF01000072_gene3523	7.483e-112	375.0	COG1819@1|root,COG1819@2|Bacteria,1G1XQ@1117|Cyanobacteria,1H9CT@1150|Oscillatoriales	1117|Cyanobacteria	CG	COGs COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase	crtX	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
MMS3_k127_2982000_6	1382356.JQMP01000003_gene1491	1.356e-80	298.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2G8KM@200795|Chloroflexi	2|Bacteria	P	PFAM copper resistance protein CopC	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07156,ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1,9.B.62.2	-	-	CopC,CopD,YtkA
MMS3_k127_2982000_11	700598.Niako_5150	1.092e-15	92.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMS3_k127_2982000_12	1032480.MLP_00120	1.194e-06	61.0	COG0515@1|root,COG0823@1|root,COG3170@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,COG3170@2|Bacteria,2GIW5@201174|Actinobacteria,4DUI1@85009|Propionibacteriales	201174|Actinobacteria	KLTU	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMS3_k127_2982000_4	479434.Sthe_1841	3.343e-123	404.0	COG0346@1|root,COG0346@2|Bacteria,2G5Y9@200795|Chloroflexi,27XVR@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMS3_k127_2982000_1	479434.Sthe_3501	7.674e-250	779.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,27Y57@189775|Thermomicrobia	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	putA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iAF987.Gmet_3512	Aldedh,Pro_dh,Pro_dh-DNA_bdg
MMS3_k127_2982000_0	479434.Sthe_1742	0.0	1282.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_2982000_2	479434.Sthe_0528	2.188e-201	632.0	COG0006@1|root,COG0006@2|Bacteria,2GAAQ@200795|Chloroflexi,27Z28@189775|Thermomicrobia	189775|Thermomicrobia	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
MMS3_k127_2982000_10	479434.Sthe_0089	5.56e-22	100.0	COG1734@1|root,COG1734@2|Bacteria,2G7BM@200795|Chloroflexi,27YP5@189775|Thermomicrobia	189775|Thermomicrobia	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
MMS3_k127_2982000_8	1459636.NTE_02460	9.396e-46	173.0	COG1926@1|root,arCOG00041@2157|Archaea	2157|Archaea	F	phosphoribosyltransferases	prt	-	-	ko:K04096,ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
MMS3_k127_2982000_7	472759.Nhal_2962	3.114e-78	267.0	COG0462@1|root,COG0462@2|Bacteria,1QHJ7@1224|Proteobacteria,1RZJH@1236|Gammaproteobacteria,1WZXT@135613|Chromatiales	135613|Chromatiales	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
MMS3_k127_2995009_4	661367.LLO_3200	1.043e-07	56.0	COG2027@1|root,COG2027@2|Bacteria,1PCD1@1224|Proteobacteria,1SXBP@1236|Gammaproteobacteria,1JC5D@118969|Legionellales	118969|Legionellales	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K01286,ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
MMS3_k127_2995009_2	868131.MSWAN_1542	9.987e-36	144.0	arCOG09452@1|root,arCOG09452@2157|Archaea,2Y0CR@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_2995009_1	653045.Strvi_4787	1.957e-58	209.0	COG0346@1|root,COG0346@2|Bacteria,2I94W@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_2995009_3	1463921.JODF01000136_gene6051	6.222e-29	121.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMS3_k127_2995009_0	1408418.JNJH01000008_gene2519	6.074e-97	332.0	COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria,2UF0X@28211|Alphaproteobacteria,2JYC8@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
MMS3_k127_2995009_5	926692.AZYG01000064_gene941	0.0001312	50.0	COG0392@1|root,COG0392@2|Bacteria,1VC5W@1239|Firmicutes,24K4M@186801|Clostridia,3WBXT@53433|Halanaerobiales	186801|Clostridia	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMS3_k127_2998881_3	479434.Sthe_0278	7.164e-18	89.0	COG1388@1|root,COG1388@2|Bacteria,2G99N@200795|Chloroflexi,27YNY@189775|Thermomicrobia	189775|Thermomicrobia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
MMS3_k127_2998881_1	479434.Sthe_0281	1.302e-72	249.0	COG0558@1|root,COG0558@2|Bacteria,2G6RT@200795|Chloroflexi,27YAI@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_2998881_0	479434.Sthe_0282	8.458e-184	583.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,27XU5@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_2998881_2	479434.Sthe_0284	6.762e-35	142.0	COG3881@1|root,COG3881@2|Bacteria,2G9T4@200795|Chloroflexi	200795|Chloroflexi	S	PFAM PRC-barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PRC
MMS3_k127_2998881_4	479434.Sthe_0290	3.585e-15	75.0	COG1028@1|root,COG1028@2|Bacteria,2G8II@200795|Chloroflexi,27XKN@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_3005713_11	1174528.JH992898_gene3564	6.734e-25	107.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria,1JIE9@1189|Stigonemataceae	1117|Cyanobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
MMS3_k127_3005713_4	1123237.Salmuc_01604	7.781e-77	268.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VETJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_3005713_2	479434.Sthe_0679	1.284e-89	305.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi,27XFE@189775|Thermomicrobia	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_3005713_9	1121380.JNIW01000013_gene2005	5.692e-46	186.0	COG0747@1|root,COG0747@2|Bacteria,1WIYQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3005713_6	479434.Sthe_0681	4.219e-61	218.0	COG2186@1|root,COG2186@2|Bacteria,2GBBV@200795|Chloroflexi,27YQ1@189775|Thermomicrobia	189775|Thermomicrobia	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
MMS3_k127_3005713_1	479434.Sthe_3144	3.989e-92	309.0	COG0346@1|root,COG0346@2|Bacteria,2G8K0@200795|Chloroflexi,27YCV@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
MMS3_k127_3005713_3	285514.JNWO01000022_gene561	1.845e-89	303.0	COG0596@1|root,COG0596@2|Bacteria,2I26T@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the peptidase S33 family	pip	-	3.4.11.5,3.5.1.101	ko:K01259,ko:K18457	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
MMS3_k127_3005713_10	1122165.AUHS01000003_gene2182	2.28e-44	173.0	COG3173@1|root,COG3173@2|Bacteria,1QC6X@1224|Proteobacteria,1T7VX@1236|Gammaproteobacteria,1JFXE@118969|Legionellales	118969|Legionellales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_3005713_8	1210908.HSB1_10010	1.609e-47	174.0	COG2514@1|root,arCOG06106@2157|Archaea,2Y43R@28890|Euryarchaeota,23ZV2@183963|Halobacteria	183963|Halobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_3005713_0	479434.Sthe_2099	1.589e-135	440.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR
MMS3_k127_3005713_5	402777.KB235903_gene1332	1.351e-71	248.0	COG1279@1|root,COG1279@2|Bacteria,1GQJ3@1117|Cyanobacteria,1HHX6@1150|Oscillatoriales	1117|Cyanobacteria	S	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
MMS3_k127_3005713_7	1382306.JNIM01000001_gene2669	1.998e-60	219.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_3014136_7	479434.Sthe_2591	1.142e-74	265.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_3014136_11	33876.JNXY01000020_gene4470	4.787e-28	118.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4DJQN@85008|Micromonosporales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
MMS3_k127_3014136_0	479434.Sthe_3210	3.702e-270	847.0	COG0823@1|root,COG3391@1|root,COG0823@2|Bacteria,COG3391@2|Bacteria,2GBHT@200795|Chloroflexi,27XYS@189775|Thermomicrobia	189775|Thermomicrobia	U	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PD40
MMS3_k127_3014136_10	1395587.P364_0131665	1.512e-44	177.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,26RFG@186822|Paenibacillaceae	91061|Bacilli	EGP	Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3014136_1	479434.Sthe_2998	2.26e-243	762.0	COG0318@1|root,COG0318@2|Bacteria,2G5XA@200795|Chloroflexi,27YWU@189775|Thermomicrobia	189775|Thermomicrobia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3014136_2	479434.Sthe_3212	1.626e-128	418.0	COG1216@1|root,COG1216@2|Bacteria,2G5U8@200795|Chloroflexi,27XGN@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
MMS3_k127_3014136_6	479434.Sthe_3213	4.731e-75	270.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	2|Bacteria	M	PFAM sugar transferase	wcaJ	-	-	ko:K03606,ko:K20997	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
MMS3_k127_3014136_4	479434.Sthe_3215	1.363e-104	349.0	COG0346@1|root,COG0346@2|Bacteria,2G5Y9@200795|Chloroflexi,27XVR@189775|Thermomicrobia	200795|Chloroflexi	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMS3_k127_3014136_3	479434.Sthe_3217	8.005e-107	354.0	COG0265@1|root,COG0265@2|Bacteria,2GBRP@200795|Chloroflexi,27Z1U@189775|Thermomicrobia	189775|Thermomicrobia	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_3014136_9	479434.Sthe_3218	6.593e-51	190.0	COG2197@1|root,COG2197@2|Bacteria,2G73R@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
MMS3_k127_3014136_8	479434.Sthe_3219	1.766e-61	216.0	2AZF8@1|root,31RP4@2|Bacteria,2GBAW@200795|Chloroflexi,27YKD@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3014136_5	479434.Sthe_3222	7.725e-76	259.0	COG3387@1|root,COG3387@2|Bacteria,2G7S0@200795|Chloroflexi,27Y4H@189775|Thermomicrobia	189775|Thermomicrobia	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
MMS3_k127_3026331_14	1463825.JNXC01000040_gene5228	1.39e-06	59.0	COG2732@1|root,COG2732@2|Bacteria,2GX72@201174|Actinobacteria	201174|Actinobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
MMS3_k127_3026331_9	1082933.MEA186_29382	1.42e-30	132.0	2DR1U@1|root,339TE@2|Bacteria,1NWT6@1224|Proteobacteria,2USV2@28211|Alphaproteobacteria,43QRD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3026331_2	479434.Sthe_3059	1.563e-88	297.0	COG1247@1|root,COG1247@2|Bacteria,2G8IS@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
MMS3_k127_3026331_0	479434.Sthe_3063	1.045e-192	610.0	COG1914@1|root,COG1914@2|Bacteria,2G67K@200795|Chloroflexi,27XR1@189775|Thermomicrobia	189775|Thermomicrobia	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
MMS3_k127_3026331_3	479434.Sthe_3064	5.956e-82	289.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,27YAE@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_3026331_11	926569.ANT_20740	7.191e-25	111.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3026331_13	1382356.JQMP01000003_gene2338	8.029e-09	68.0	2BQJQ@1|root,32JFR@2|Bacteria,2GA0E@200795|Chloroflexi,27YBB@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3026331_12	479434.Sthe_3065	3.365e-17	87.0	2A4W2@1|root,30THR@2|Bacteria,2GBFS@200795|Chloroflexi,27ZC4@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3026331_1	269799.Gmet_3488	4.676e-94	322.0	2DBVK@1|root,2ZBBH@2|Bacteria,1PWZS@1224|Proteobacteria,432W2@68525|delta/epsilon subdivisions,2WXWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
MMS3_k127_3026331_7	479434.Sthe_0536	3.346e-41	159.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
MMS3_k127_3026331_4	479434.Sthe_3066	2.23e-51	185.0	COG3467@1|root,COG3467@2|Bacteria,2G70M@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
MMS3_k127_3026331_6	479434.Sthe_3067	1.124e-44	164.0	COG0640@1|root,COG0640@2|Bacteria,2G7C3@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
MMS3_k127_3026331_5	1382306.JNIM01000001_gene1924	4.334e-46	171.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
MMS3_k127_3026331_10	864702.OsccyDRAFT_4824	7.104e-29	122.0	COG2852@1|root,COG2852@2|Bacteria,1G6SC@1117|Cyanobacteria,1HC1Y@1150|Oscillatoriales	1117|Cyanobacteria	V	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
MMS3_k127_3026331_8	479434.Sthe_3084	4.227e-41	154.0	COG4149@1|root,COG4149@2|Bacteria,2G6FA@200795|Chloroflexi,27YA5@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
MMS3_k127_3031441_2	1105367.CG50_02710	2.446e-55	199.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
MMS3_k127_3031441_1	1461694.ATO9_21370	0.0	1053.0	COG1431@1|root,COG1431@2|Bacteria,1R5TD@1224|Proteobacteria,2U0RE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3031441_0	1461694.ATO9_21365	0.0	1058.0	COG1537@1|root,COG1537@2|Bacteria,1R56J@1224|Proteobacteria,2TTXH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
MMS3_k127_3032145_5	479434.Sthe_1517	1.397e-33	130.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi,27XI0@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
MMS3_k127_3032145_0	479434.Sthe_1518	0.0	1007.0	COG0129@1|root,COG0129@2|Bacteria,2G5QW@200795|Chloroflexi,27XQ0@189775|Thermomicrobia	200795|Chloroflexi	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
MMS3_k127_3032145_4	479434.Sthe_1519	9.562e-65	225.0	COG0822@1|root,COG0822@2|Bacteria,2G6WC@200795|Chloroflexi,27YET@189775|Thermomicrobia	189775|Thermomicrobia	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMS3_k127_3032145_1	479434.Sthe_1520	6.935e-159	505.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi,27XNT@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
MMS3_k127_3032145_3	479434.Sthe_1521	1.599e-67	231.0	COG0735@1|root,COG0735@2|Bacteria,2G92T@200795|Chloroflexi,27YA1@189775|Thermomicrobia	189775|Thermomicrobia	K	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMS3_k127_3032145_2	479434.Sthe_1522	4.312e-71	243.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi,27XVN@189775|Thermomicrobia	189775|Thermomicrobia	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMS3_k127_3034882_1	1532558.JL39_10705	4.266e-89	317.0	COG0747@1|root,COG0747@2|Bacteria,1R63Z@1224|Proteobacteria,2U2AU@28211|Alphaproteobacteria,4B94U@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3034882_0	1217720.ALOX01000079_gene3272	4.687e-103	345.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_3034882_2	690585.JNNU01000038_gene1102	0.0003683	45.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2TUCW@28211|Alphaproteobacteria,4BNAM@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
MMS3_k127_303864_0	479434.Sthe_1129	0.0	1413.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27Z0Q@189775|Thermomicrobia	189775|Thermomicrobia	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
MMS3_k127_303864_4	479434.Sthe_2382	9.212e-57	202.0	2A4UP@1|root,30TG8@2|Bacteria,2GA4A@200795|Chloroflexi,27Z73@189775|Thermomicrobia	189775|Thermomicrobia	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_303864_2	1221522.B723_11275	8.359e-138	446.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,1RYKW@1236|Gammaproteobacteria,1YSM6@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
MMS3_k127_303864_7	1479238.JQMZ01000001_gene575	2.781e-29	127.0	COG4923@1|root,COG4923@2|Bacteria,1MY1R@1224|Proteobacteria,2U4CU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
MMS3_k127_303864_1	1382356.JQMP01000003_gene2064	1.177e-200	636.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi,27YVS@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
MMS3_k127_303864_3	479434.Sthe_2697	1.235e-78	269.0	COG1656@1|root,COG1977@1|root,COG1656@2|Bacteria,COG1977@2|Bacteria,2G6GZ@200795|Chloroflexi,27Y8I@189775|Thermomicrobia	189775|Thermomicrobia	H	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
MMS3_k127_303864_6	684949.ATTJ01000001_gene1764	2.443e-44	167.0	2E655@1|root,330TY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_303864_8	1429046.RR21198_4115	1.625e-28	124.0	COG0671@1|root,COG0671@2|Bacteria,2IAXK@201174|Actinobacteria,4FWWC@85025|Nocardiaceae	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
MMS3_k127_303864_5	1118054.CAGW01000024_gene451	7.554e-53	190.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,26SYE@186822|Paenibacillaceae	91061|Bacilli	E	peptidase M20	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3055532_0	443598.AUFA01000027_gene1914	1.344e-129	425.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TT6G@28211|Alphaproteobacteria,3JWEQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_3055532_1	479434.Sthe_3353	1.033e-66	237.0	COG1295@1|root,COG1295@2|Bacteria,2GARF@200795|Chloroflexi,27Z8N@189775|Thermomicrobia	189775|Thermomicrobia	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
MMS3_k127_3055532_2	1121380.JNIW01000020_gene3587	2.736e-33	139.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMS3_k127_3076538_5	479434.Sthe_0383	2.031e-61	213.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi,27XYG@189775|Thermomicrobia	189775|Thermomicrobia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
MMS3_k127_3076538_4	479434.Sthe_0313	4.604e-80	270.0	COG5405@1|root,COG5405@2|Bacteria,2GA07@200795|Chloroflexi,27Y6T@189775|Thermomicrobia	189775|Thermomicrobia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
MMS3_k127_3076538_0	1382356.JQMP01000004_gene669	5.509e-178	570.0	COG1220@1|root,COG1220@2|Bacteria,2GBH6@200795|Chloroflexi,27XKZ@189775|Thermomicrobia	189775|Thermomicrobia	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	-	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
MMS3_k127_3076538_3	479434.Sthe_0311	1.028e-111	365.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3076538_2	479434.Sthe_0310	7.612e-114	376.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi,27XTH@189775|Thermomicrobia	189775|Thermomicrobia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMS3_k127_3076538_1	479434.Sthe_0309	4.679e-133	443.0	COG4166@1|root,COG4166@2|Bacteria,2G8A0@200795|Chloroflexi,27XKE@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3083371_0	264732.Moth_1967	2.71e-198	628.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,24AJ7@186801|Clostridia,42HNB@68295|Thermoanaerobacterales	186801|Clostridia	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_3083371_1	1382306.JNIM01000001_gene2318	1.117e-171	544.0	COG0146@1|root,COG0146@2|Bacteria	2|Bacteria	EQ	ligase activity	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_3098421_3	1382356.JQMP01000003_gene1447	7.132e-104	353.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMS3_k127_3098421_6	1128421.JAGA01000002_gene895	4.602e-80	273.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
MMS3_k127_3098421_1	1382356.JQMP01000003_gene1449	7.169e-134	438.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_3098421_10	228405.HNE_0924	1.109e-49	188.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,43XCC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	IQ	short chain dehydrogenase reductase family	-	-	1.1.1.304,1.1.1.76	ko:K18009	ko00650,map00650	-	R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
MMS3_k127_3098421_7	1173028.ANKO01000139_gene671	8.574e-71	254.0	COG1502@1|root,COG1502@2|Bacteria,1G01I@1117|Cyanobacteria,1H79E@1150|Oscillatoriales	2|Bacteria	I	TIGRFAM Competence protein ComEA, helix-hairpin-helix	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
MMS3_k127_3098421_8	479434.Sthe_3267	4.851e-68	240.0	COG1989@1|root,COG1989@2|Bacteria,2G797@200795|Chloroflexi,27YGY@189775|Thermomicrobia	189775|Thermomicrobia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
MMS3_k127_3098421_4	309801.trd_A0871	2.712e-91	307.0	COG0169@1|root,COG0169@2|Bacteria,2G6FG@200795|Chloroflexi,27XST@189775|Thermomicrobia	189775|Thermomicrobia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
MMS3_k127_3098421_0	479434.Sthe_3265	4.726e-137	445.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi,27XHU@189775|Thermomicrobia	189775|Thermomicrobia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
MMS3_k127_3098421_2	479434.Sthe_3264	1.215e-129	422.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,27XIQ@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
MMS3_k127_3098421_9	1382356.JQMP01000004_gene129	1.297e-66	232.0	COG0251@1|root,COG0251@2|Bacteria,2G7G4@200795|Chloroflexi,27Y7P@189775|Thermomicrobia	189775|Thermomicrobia	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
MMS3_k127_3098421_12	1304880.JAGB01000001_gene867	3.37e-40	163.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_3098421_5	479434.Sthe_3051	7.772e-90	305.0	COG0384@1|root,COG0384@2|Bacteria,2G7U6@200795|Chloroflexi,27ZAQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
MMS3_k127_3098421_11	479434.Sthe_3260	3.45e-48	175.0	COG1194@1|root,COG1194@2|Bacteria,2G62P@200795|Chloroflexi,27XJQ@189775|Thermomicrobia	189775|Thermomicrobia	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_3099130_4	479434.Sthe_1323	8.186e-20	93.0	COG0438@1|root,COG0438@2|Bacteria,2G6Z9@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
MMS3_k127_3099130_3	479434.Sthe_1322	2.189e-27	111.0	COG2835@1|root,COG2835@2|Bacteria,2GBCC@200795|Chloroflexi,27YRI@189775|Thermomicrobia	189775|Thermomicrobia	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
MMS3_k127_3099130_1	479434.Sthe_1321	2.068e-166	530.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi,27Y08@189775|Thermomicrobia	189775|Thermomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
MMS3_k127_3099130_2	479434.Sthe_1320	1.302e-140	454.0	COG0809@1|root,COG0809@2|Bacteria,2G5UZ@200795|Chloroflexi,27XKC@189775|Thermomicrobia	189775|Thermomicrobia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
MMS3_k127_3099130_0	479434.Sthe_1319	2.138e-224	703.0	COG1866@1|root,COG1866@2|Bacteria,2G5TD@200795|Chloroflexi,27YZT@189775|Thermomicrobia	189775|Thermomicrobia	H	Phosphoenolpyruvate carboxykinase	-	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
MMS3_k127_3100800_4	33898.JRHJ01000069_gene7389	1.512e-13	77.0	COG1247@1|root,COG1247@2|Bacteria,2GR9D@201174|Actinobacteria	201174|Actinobacteria	M	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMS3_k127_3100800_0	479434.Sthe_2596	1.675e-268	839.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	2|Bacteria	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_3100800_3	1123229.AUBC01000047_gene3803	2.761e-58	211.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2U28G@28211|Alphaproteobacteria,3JVNQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Asp/Glu/Hydantoin racemase	MA20_32210	-	5.1.99.3	ko:K16841	ko00230,ko01120,map00230,map01120	-	R03925	RC01027	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
MMS3_k127_3100800_1	479434.Sthe_3053	7.57e-120	392.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi,27XQA@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
MMS3_k127_3100800_2	479434.Sthe_3353	8.343e-69	244.0	COG1295@1|root,COG1295@2|Bacteria,2GARF@200795|Chloroflexi,27Z8N@189775|Thermomicrobia	189775|Thermomicrobia	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
MMS3_k127_3103341_10	335543.Sfum_1832	6.462e-10	68.0	2EHG8@1|root,33B84@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_3103341_3	479434.Sthe_2955	4.994e-197	623.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3103341_7	288000.BBta_6235	4.435e-31	125.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,3JZF4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
MMS3_k127_3103341_8	29540.C481_03137	1.345e-12	75.0	COG0262@1|root,arCOG01490@2157|Archaea,2XXBJ@28890|Euryarchaeota,23VPE@183963|Halobacteria	183963|Halobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMS3_k127_3103341_5	479434.Sthe_2112	6.372e-119	391.0	2A711@1|root,30VW9@2|Bacteria,2GB7C@200795|Chloroflexi,27XPI@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3103341_0	479434.Sthe_2092	5.243e-294	939.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.1.12.1,3.6.4.12	ko:K01144,ko:K07464,ko:K16898	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
MMS3_k127_3103341_1	479434.Sthe_2091	6.926e-294	936.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
MMS3_k127_3103341_2	479434.Sthe_2090	2.307e-276	862.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G7MH@200795|Chloroflexi,27XJR@189775|Thermomicrobia	2|Bacteria	EU	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
MMS3_k127_3103341_4	479434.Sthe_1846	2.422e-131	427.0	28J6C@1|root,2Z923@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_312204_3	479434.Sthe_1588	4.885e-42	157.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,27XNH@189775|Thermomicrobia	189775|Thermomicrobia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
MMS3_k127_312204_0	479434.Sthe_1589	1.663e-197	623.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,27XZ3@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMS3_k127_312204_1	479434.Sthe_1590	1.211e-170	541.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,27XT7@189775|Thermomicrobia	189775|Thermomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
MMS3_k127_312204_2	479434.Sthe_1591	6.162e-116	377.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,27Y2S@189775|Thermomicrobia	189775|Thermomicrobia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
MMS3_k127_3131605_4	479434.Sthe_2537	6.437e-07	54.0	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	chpR	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0032991,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044877,GO:0046983,GO:0051259,GO:0051291,GO:0065003,GO:0071840,GO:0097159,GO:0097351,GO:1901363	-	ko:K07172,ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
MMS3_k127_3131605_3	292459.STH876	5.861e-19	93.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,24J85@186801|Clostridia	186801|Clostridia	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
MMS3_k127_3131605_2	1395587.P364_0124115	2.797e-25	119.0	2DZXU@1|root,32VMR@2|Bacteria,1VBBV@1239|Firmicutes,4HPWN@91061|Bacilli,26ZA3@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3131605_1	269797.Mbar_A2582	2.639e-87	297.0	COG0596@1|root,arCOG01660@2157|Archaea,2Y2WA@28890|Euryarchaeota,2NAHS@224756|Methanomicrobia	224756|Methanomicrobia	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_3131605_0	485913.Krac_3359	2.738e-164	531.0	COG0477@1|root,COG2814@2|Bacteria,2G814@200795|Chloroflexi	2|Bacteria	P	SPTR A9B396 Drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3134005_1	479434.Sthe_0894	8.958e-76	268.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,27Z1J@189775|Thermomicrobia	189775|Thermomicrobia	M	Tetratricopeptide repeat	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
MMS3_k127_3134005_0	479434.Sthe_1509	2.345e-80	272.0	COG0693@1|root,COG0693@2|Bacteria,2G8WZ@200795|Chloroflexi,27Y86@189775|Thermomicrobia	189775|Thermomicrobia	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
MMS3_k127_3134005_2	208596.CAR_c10900	5.031e-09	60.0	COG0726@1|root,COG1388@1|root,COG0726@2|Bacteria,COG1388@2|Bacteria,1UZ7Q@1239|Firmicutes,4IPRX@91061|Bacilli,27FRM@186828|Carnobacteriaceae	91061|Bacilli	GM	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
MMS3_k127_314590_2	479434.Sthe_2517	2.266e-155	500.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,27XZ7@189775|Thermomicrobia	2|Bacteria	E	TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_314590_11	1121445.ATUZ01000014_gene1658	8.642e-06	52.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria,2MD95@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_314590_7	479434.Sthe_0756	6.98e-98	331.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi,27Z6H@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
MMS3_k127_314590_5	479434.Sthe_0755	2e-101	339.0	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi,27YUM@189775|Thermomicrobia	189775|Thermomicrobia	H	ApbE family	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMS3_k127_314590_10	479434.Sthe_0753	2.624e-21	96.0	COG1141@1|root,COG1141@2|Bacteria,2GBFF@200795|Chloroflexi,27ZAP@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_15
MMS3_k127_314590_3	479434.Sthe_0752	1.714e-154	499.0	COG1894@1|root,COG1894@2|Bacteria,2GBW4@200795|Chloroflexi,27YVY@189775|Thermomicrobia	189775|Thermomicrobia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
MMS3_k127_314590_9	309801.trd_1338	1.148e-51	194.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K00406,ko:K03889	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00151,M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
MMS3_k127_314590_8	1382356.JQMP01000001_gene774	2.979e-90	305.0	COG0745@1|root,COG0745@2|Bacteria,2GABY@200795|Chloroflexi,27Z4B@189775|Thermomicrobia	189775|Thermomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_314590_4	1382356.JQMP01000001_gene773	1.023e-107	365.0	COG5002@1|root,COG5002@2|Bacteria,2G6F5@200795|Chloroflexi,27Z71@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMS3_k127_314590_1	1382356.JQMP01000003_gene1797	2.948e-205	648.0	COG0477@1|root,COG2814@2|Bacteria,2GA6K@200795|Chloroflexi,27XGR@189775|Thermomicrobia	189775|Thermomicrobia	P	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_314590_0	479434.Sthe_0093	0.0	1251.0	COG0466@1|root,COG0466@2|Bacteria,2G7KC@200795|Chloroflexi,27YSH@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMS3_k127_314590_6	935836.JAEL01000020_gene983	1.788e-98	335.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,1ZDIH@1386|Bacillus	91061|Bacilli	S	amidohydrolase	hipO3	-	-	ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3150292_1	479434.Sthe_0894	7.014e-28	126.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,27Z1J@189775|Thermomicrobia	189775|Thermomicrobia	M	Tetratricopeptide repeat	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
MMS3_k127_3150292_0	1449353.JQMQ01000005_gene1865	7.67e-199	628.0	COG3579@1|root,COG3579@2|Bacteria,2GNYU@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase C1-like family	pepC2	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
MMS3_k127_3155586_7	479434.Sthe_1640	1.344e-26	120.0	2A4VC@1|root,30TGY@2|Bacteria,2GA54@200795|Chloroflexi,27Z9W@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3155586_1	479434.Sthe_1638	5.232e-152	490.0	COG0624@1|root,COG0624@2|Bacteria,2G60R@200795|Chloroflexi,27Y02@189775|Thermomicrobia	189775|Thermomicrobia	E	peptidase dimerisation domain protein	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_3155586_4	479434.Sthe_1637	3.338e-87	293.0	COG1432@1|root,COG1432@2|Bacteria,2G7FF@200795|Chloroflexi,27YBW@189775|Thermomicrobia	189775|Thermomicrobia	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
MMS3_k127_3155586_2	1382356.JQMP01000004_gene323	5.697e-147	472.0	COG3804@1|root,COG3804@2|Bacteria,2GA3D@200795|Chloroflexi,27YZV@189775|Thermomicrobia	189775|Thermomicrobia	S	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
MMS3_k127_3155586_6	479434.Sthe_1636	2.387e-38	148.0	28VU2@1|root,2ZHVR@2|Bacteria,2GA15@200795|Chloroflexi,27YI9@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3155586_3	479434.Sthe_1635	1.965e-106	355.0	COG1397@1|root,COG1397@2|Bacteria,2G7F9@200795|Chloroflexi,27Y69@189775|Thermomicrobia	189775|Thermomicrobia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
MMS3_k127_3155586_5	479434.Sthe_1634	1.027e-73	256.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi,27YBK@189775|Thermomicrobia	189775|Thermomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS3_k127_3155586_0	479434.Sthe_1632	1.684e-182	577.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi,27XY0@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMS3_k127_3160273_3	1487953.JMKF01000053_gene1781	3.107e-47	177.0	COG3554@1|root,COG3554@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
MMS3_k127_3160273_2	479434.Sthe_3020	5.924e-59	214.0	COG1670@1|root,COG1670@2|Bacteria,2G6UG@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_3160273_1	479434.Sthe_3023	1.356e-81	280.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,27Y8T@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
MMS3_k127_3160273_0	479434.Sthe_3024	2.474e-147	474.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,27XZC@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
MMS3_k127_3185151_4	479434.Sthe_3505	6.16e-59	210.0	COG1011@1|root,COG1011@2|Bacteria,2G78N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
MMS3_k127_3185151_3	479434.Sthe_3506	2.756e-74	259.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2G7EW@200795|Chloroflexi	200795|Chloroflexi	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
MMS3_k127_3185151_1	358681.BBR47_26500	1.069e-91	311.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HDBB@91061|Bacilli,274T8@186822|Paenibacillaceae	91061|Bacilli	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_3185151_2	649638.Trad_0942	4.81e-90	306.0	COG0601@1|root,COG0601@2|Bacteria,1WIGY@1297|Deinococcus-Thermus	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_3185151_0	644966.Tmar_1338	3.369e-116	393.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3192222_3	479434.Sthe_3443	1.785e-32	133.0	COG0726@1|root,COG0726@2|Bacteria,2G76U@200795|Chloroflexi	200795|Chloroflexi	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Polysacc_deac_1
MMS3_k127_3192222_2	1298880.AUEV01000002_gene1792	4.317e-70	244.0	COG0500@1|root,COG2226@2|Bacteria,2IBY2@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_3192222_1	479434.Sthe_3231	6.316e-115	376.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi,27Y1C@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
MMS3_k127_3192222_0	43989.cce_2032	7.97e-181	617.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGMH@43988|Cyanothece	1117|Cyanobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9
MMS3_k127_3199748_0	221288.JH992901_gene2043	2.063e-74	280.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JHSG@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
MMS3_k127_3209266_1	1280950.HJO_12726	1.307e-150	487.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,43WC9@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	COG0076 Glutamate decarboxylase and related PLP-dependent proteins	MA20_08345	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
MMS3_k127_3209266_0	1408419.JHYG01000009_gene92	1.249e-152	500.0	COG0520@1|root,COG0520@2|Bacteria,1QEVJ@1224|Proteobacteria,2TX67@28211|Alphaproteobacteria,2JW3S@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_321277_3	479434.Sthe_2665	8.081e-120	394.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
MMS3_k127_321277_5	479434.Sthe_2664	1.253e-64	225.0	COG1522@1|root,COG1522@2|Bacteria,2G77K@200795|Chloroflexi,27YBX@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcription regulator	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_AsnC-type
MMS3_k127_321277_0	479434.Sthe_2663	2.501e-197	622.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27XJ3@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_321277_6	583355.Caka_3045	6.591e-21	100.0	2B0D4@1|root,31SQA@2|Bacteria,46VUX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_321277_4	479434.Sthe_2660	1.712e-108	363.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi,27XRN@189775|Thermomicrobia	189775|Thermomicrobia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
MMS3_k127_321277_2	479434.Sthe_2659	1.053e-126	410.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi,27XPM@189775|Thermomicrobia	189775|Thermomicrobia	D	Anion-transporting ATPase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMS3_k127_321277_1	479434.Sthe_2654	1.901e-180	584.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZW@200795|Chloroflexi,27YUJ@189775|Thermomicrobia	189775|Thermomicrobia	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMS3_k127_3223522_0	525904.Tter_0782	5.805e-118	386.0	COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_3223522_1	479434.Sthe_1447	1.889e-106	357.0	2A4QB@1|root,30TBJ@2|Bacteria,2GB9N@200795|Chloroflexi,27YCD@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,bPH_5
MMS3_k127_3223522_5	479434.Sthe_1445	5.095e-82	277.0	COG0558@1|root,COG0558@2|Bacteria,2G7HQ@200795|Chloroflexi,27YAM@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMS3_k127_3223522_3	479434.Sthe_1444	4.714e-86	294.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	serB1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	2.3.1.51,3.1.3.3	ko:K15781,ko:K21830	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,HAD
MMS3_k127_3223522_4	479434.Sthe_1443	2.286e-82	286.0	COG1560@1|root,COG1560@2|Bacteria,2G9GW@200795|Chloroflexi,27Z5D@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMS3_k127_3223522_6	479434.Sthe_1441	1.935e-63	222.0	COG1666@1|root,COG1666@2|Bacteria,2G6TD@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
MMS3_k127_3223522_8	187272.Mlg_1793	9.58e-28	120.0	COG4195@1|root,COG4195@2|Bacteria,1MZZB@1224|Proteobacteria,1SH88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Poly-gamma-glutamate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Gamma_PGA_hydro
MMS3_k127_3223522_2	479434.Sthe_1440	4.416e-95	328.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	200795|Chloroflexi	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
MMS3_k127_3223522_9	1146883.BLASA_1078	7.835e-06	51.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESQP@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS3_k127_3223522_7	479434.Sthe_1438	7.627e-43	158.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,27XYD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
MMS3_k127_3226090_1	1382356.JQMP01000004_gene575	1.096e-110	366.0	COG2234@1|root,COG2234@2|Bacteria,2G9MK@200795|Chloroflexi,27XKJ@189775|Thermomicrobia	200795|Chloroflexi	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_3226090_0	479434.Sthe_0245	2.493e-112	376.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi,27XSJ@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
MMS3_k127_3226090_3	479434.Sthe_3246	3.11e-71	252.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	3.6.3.2	ko:K01531,ko:K07027,ko:K20468	-	-	-	-	ko00000,ko01000,ko02000	3.A.3.4,4.D.2,4.D.2.4.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,LPG_synthase_TM
MMS3_k127_3226090_4	330214.NIDE3855	3.317e-20	92.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
MMS3_k127_3226090_2	1288494.EBAPG3_2190	3.002e-95	321.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,3725Z@32003|Nitrosomonadales	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
MMS3_k127_3226981_1	648885.KB316282_gene268	6.081e-31	129.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U7NJ@28211|Alphaproteobacteria,1JUIY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_3226981_0	1278078.G419_20850	5.04e-124	426.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC
MMS3_k127_3230709_1	479434.Sthe_0126	5.914e-135	436.0	COG2515@1|root,COG2515@2|Bacteria,2G6PX@200795|Chloroflexi,27YZ5@189775|Thermomicrobia	189775|Thermomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
MMS3_k127_3230709_4	1499967.BAYZ01000096_gene4317	2.836e-31	133.0	COG1402@1|root,COG1402@2|Bacteria,2NRPM@2323|unclassified Bacteria	2|Bacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_3230709_2	521045.Kole_1086	5.131e-49	181.0	COG1670@1|root,COG1670@2|Bacteria,2GDGN@200918|Thermotogae	200918|Thermotogae	J	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
MMS3_k127_3230709_0	309801.trd_A0395	1.738e-169	551.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
MMS3_k127_3230709_3	479434.Sthe_3167	2.24e-33	134.0	2BM5I@1|root,32FP4@2|Bacteria,2GBAV@200795|Chloroflexi,27YKB@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3255359_0	266265.Bxe_C1347	2.773e-217	680.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2VMKY@28216|Betaproteobacteria,1K19C@119060|Burkholderiaceae	28216|Betaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_3255359_6	479434.Sthe_0593	4.616e-22	99.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin
MMS3_k127_3255359_3	479434.Sthe_0594	4.438e-141	462.0	COG0446@1|root,COG0446@2|Bacteria,2G6SN@200795|Chloroflexi	200795|Chloroflexi	C	BFD domain protein 2Fe-2S -binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
MMS3_k127_3255359_2	1121861.KB899912_gene1117	2.139e-197	632.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2JQP4@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase B/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydantoinase_B
MMS3_k127_3255359_1	1394178.AWOO02000001_gene1517	8.446e-201	647.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4EGC9@85012|Streptosporangiales	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_3255359_5	1382356.JQMP01000001_gene1218	6.832e-66	230.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi,27YB0@189775|Thermomicrobia	189775|Thermomicrobia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
MMS3_k127_3255359_4	479434.Sthe_2558	2.666e-74	260.0	COG1971@1|root,COG5305@1|root,COG1971@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp,PMT_2
MMS3_k127_3258281_8	479434.Sthe_1810	2.166e-71	243.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y4F@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_3258281_4	525904.Tter_2339	5.341e-133	437.0	COG1914@1|root,COG1914@2|Bacteria,2NNYP@2323|unclassified Bacteria	2|Bacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS07840	Nramp
MMS3_k127_3258281_5	525904.Tter_2338	1.151e-111	374.0	COG2239@1|root,COG2239@2|Bacteria,2NP79@2323|unclassified Bacteria	2|Bacteria	P	MgtE intracellular N domain	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
MMS3_k127_3258281_9	479434.Sthe_3201	1.895e-55	209.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad,Tad_C
MMS3_k127_3258281_13	479434.Sthe_0630	4.844e-42	154.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi,27YGX@189775|Thermomicrobia	189775|Thermomicrobia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
MMS3_k127_3258281_17	479434.Sthe_1808	3.157e-15	80.0	2A4RX@1|root,30TDB@2|Bacteria,2GBBQ@200795|Chloroflexi,27YPF@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3258281_14	479434.Sthe_1807	1.511e-39	150.0	COG0254@1|root,COG0254@2|Bacteria,2G75A@200795|Chloroflexi,27YIK@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
MMS3_k127_3258281_15	479434.Sthe_1806	7.104e-35	135.0	COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi,27YJD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
MMS3_k127_3258281_12	479434.Sthe_1805	1.964e-43	163.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi,27YJB@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
MMS3_k127_3258281_6	479434.Sthe_1804	2.392e-95	321.0	COG0181@1|root,COG0181@2|Bacteria,2G6JU@200795|Chloroflexi,27Y7G@189775|Thermomicrobia	189775|Thermomicrobia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	-	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
MMS3_k127_3258281_7	667014.Thein_0873	5.724e-88	309.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GH4Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
MMS3_k127_3258281_2	479434.Sthe_1802	1.934e-167	532.0	COG0113@1|root,COG0113@2|Bacteria,2G5QT@200795|Chloroflexi,27XTX@189775|Thermomicrobia	189775|Thermomicrobia	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
MMS3_k127_3258281_1	479434.Sthe_1801	9.238e-211	661.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_3258281_3	479434.Sthe_1800	6.827e-142	462.0	COG0373@1|root,COG0373@2|Bacteria,2G5T4@200795|Chloroflexi,27YFY@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
MMS3_k127_3258281_0	1207063.P24_13673	8.33e-231	729.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,2JQSB@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
MMS3_k127_3258281_16	479434.Sthe_1799	4.438e-16	86.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMS3_k127_3258281_10	1089551.KE386572_gene1716	2.587e-48	184.0	COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2TTBX@28211|Alphaproteobacteria,4BRAU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_3258281_11	1192034.CAP_1099	6.914e-48	177.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YYMB@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.17,4.3.1.19	ko:K17989	ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00590,R00996	RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_3264111_1	479434.Sthe_1248	1.889e-15	79.0	COG1826@1|root,COG1826@2|Bacteria,2GAXB@200795|Chloroflexi,27YQN@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMS3_k127_3264111_0	479434.Sthe_1249	2.691e-154	501.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3282193_6	357808.RoseRS_3781	1.34e-45	172.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi,374X6@32061|Chloroflexia	32061|Chloroflexia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_3282193_0	479434.Sthe_0669	0.0	1239.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
MMS3_k127_3282193_1	479434.Sthe_0666	2.055e-294	911.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	2|Bacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_3282193_5	309801.trd_1595	8.13e-47	172.0	2A4QP@1|root,30TBZ@2|Bacteria,2GA0V@200795|Chloroflexi,27YGZ@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3282193_3	479434.Sthe_2271	1.857e-145	477.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_3282193_4	479434.Sthe_0663	3.909e-118	392.0	COG0438@1|root,COG0438@2|Bacteria,2G6AR@200795|Chloroflexi,27Y71@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
MMS3_k127_3282193_2	479434.Sthe_0662	2.267e-222	704.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,2G6JZ@200795|Chloroflexi,27XJJ@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
MMS3_k127_3282215_11	479434.Sthe_2591	1.664e-21	94.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_3282215_9	479434.Sthe_2591	3.525e-40	153.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_3282215_5	479434.Sthe_2591	5.549e-73	250.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_3282215_4	1173027.Mic7113_3214	2.232e-77	267.0	COG1011@1|root,COG1011@2|Bacteria,1G4JI@1117|Cyanobacteria,1H8VT@1150|Oscillatoriales	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
MMS3_k127_3282215_2	316274.Haur_0506	2.338e-113	377.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi,376G2@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_3282215_10	1223545.GS4_36_00200	1.013e-35	152.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4GC6F@85026|Gordoniaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_3282215_8	1122197.ATWI01000012_gene605	8.851e-44	162.0	COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,1S6JH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	decarboxylase	HA62_21275	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMS3_k127_3282215_6	1192034.CAP_5130	7.106e-72	251.0	COG2375@1|root,COG2375@2|Bacteria,1R4TD@1224|Proteobacteria,42Y77@68525|delta/epsilon subdivisions,2WUMY@28221|Deltaproteobacteria,2YTV1@29|Myxococcales	28221|Deltaproteobacteria	P	Siderophore-interacting protein	mxcB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
MMS3_k127_3282215_1	1120960.ATXG01000001_gene913	1.079e-120	404.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4FKBN@85023|Microbacteriaceae	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
MMS3_k127_3282215_0	479434.Sthe_3086	9.09e-143	462.0	COG1476@1|root,COG1910@1|root,COG1476@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi,27Y40@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcriptional Regulator of molybdate metabolism, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,PBP_like
MMS3_k127_3282215_3	479434.Sthe_3085	3.543e-81	280.0	COG0725@1|root,COG0725@2|Bacteria,2G6J6@200795|Chloroflexi,27Y90@189775|Thermomicrobia	189775|Thermomicrobia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
MMS3_k127_3282215_7	479434.Sthe_3084	9.466e-67	233.0	COG4149@1|root,COG4149@2|Bacteria,2G6FA@200795|Chloroflexi,27YA5@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
MMS3_k127_3285305_4	264198.Reut_B3565	0.0005817	44.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WESA@28216|Betaproteobacteria	1224|Proteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3,6.2.1.31,6.2.1.41,6.2.1.48	ko:K00666,ko:K01897,ko:K02182,ko:K04116,ko:K16876,ko:K18661,ko:K18687	ko00061,ko00071,ko00280,ko00362,ko00365,ko00984,ko01100,ko01120,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map00362,map00365,map00984,map01100,map01120,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086,M00540	R01280,R02986,R03383,R05620,R10769	RC00004,RC00014,RC00137,RC00174,RC01438	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3285305_5	1522072.IL54_2686	0.0007284	46.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K1MV@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3285305_1	1333998.M2A_1980	6.699e-20	96.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,4BPZN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3285305_3	228405.HNE_3427	0.0001944	45.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,43X4S@69657|Hyphomonadaceae	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3285305_0	1205680.CAKO01000002_gene3129	6.379e-99	329.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3285305_2	497965.Cyan7822_0719	8.955e-06	55.0	COG1262@1|root,COG1262@2|Bacteria,1GMI4@1117|Cyanobacteria,3KKEX@43988|Cyanothece	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,SEFIR,TIR_2
MMS3_k127_3291443_0	479434.Sthe_2434	1.819e-165	533.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi,27XXA@189775|Thermomicrobia	189775|Thermomicrobia	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	PGI,TAL_FSA
MMS3_k127_3291443_7	1382356.JQMP01000003_gene1977	3.855e-08	57.0	2ADY2@1|root,313Q9@2|Bacteria,2GBFU@200795|Chloroflexi,27ZC7@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3291443_1	479434.Sthe_2181	5.211e-160	520.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi,27XUT@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
MMS3_k127_3291443_3	479434.Sthe_2180	6.961e-83	282.0	COG0842@1|root,COG0842@2|Bacteria,2G8GV@200795|Chloroflexi,27Y6U@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_3291443_2	479434.Sthe_2179	3.404e-144	463.0	COG1131@1|root,COG1131@2|Bacteria,2G7SA@200795|Chloroflexi,27XY4@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3291443_6	479434.Sthe_2176	8.249e-51	183.0	COG2322@1|root,COG2322@2|Bacteria,2GAA1@200795|Chloroflexi,27YKU@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
MMS3_k127_3291443_4	1408823.AXUS01000005_gene2601	3.963e-78	272.0	COG2866@1|root,COG2866@2|Bacteria,1TSIY@1239|Firmicutes,249Z5@186801|Clostridia	186801|Clostridia	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
MMS3_k127_3296275_1	479434.Sthe_0137	4.428e-181	574.0	COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi,27Y3N@189775|Thermomicrobia	189775|Thermomicrobia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMS3_k127_3296275_2	187272.Mlg_1158	9.936e-21	96.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria,1X0JQ@135613|Chromatiales	135613|Chromatiales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3296275_0	479434.Sthe_0131	1.165e-273	857.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi,27XU1@189775|Thermomicrobia	189775|Thermomicrobia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
MMS3_k127_3296275_3	709986.Deima_2452	0.000267	45.0	COG1167@1|root,COG1167@2|Bacteria	2|Bacteria	K	transaminase activity	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
MMS3_k127_3303772_1	479434.Sthe_2218	4.976e-95	321.0	COG0665@1|root,COG0665@2|Bacteria,2GABA@200795|Chloroflexi,27YZW@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_3303772_0	479434.Sthe_2845	5.075e-108	355.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_3303772_2	554065.XP_005849672.1	1.601e-51	192.0	COG1028@1|root,KOG0725@2759|Eukaryota,37Z8G@33090|Viridiplantae,34JXX@3041|Chlorophyta	3041|Chlorophyta	Q	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3303772_3	937777.Deipe_1201	8.12e-50	188.0	COG2021@1|root,COG2021@2|Bacteria,1WNIN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_3303772_4	1382304.JNIL01000001_gene1495	2.151e-40	152.0	COG5476@1|root,COG5476@2|Bacteria,1UY0D@1239|Firmicutes,4HDB2@91061|Bacilli,279I8@186823|Alicyclobacillaceae	91061|Bacilli	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
MMS3_k127_3313783_0	479434.Sthe_1056	1.175e-151	483.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
MMS3_k127_3313783_3	479434.Sthe_1055	2.101e-60	211.0	COG0200@1|root,COG0200@2|Bacteria,2G6T9@200795|Chloroflexi,27YEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
MMS3_k127_3313783_7	479434.Sthe_1054	1.544e-25	106.0	COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi,27YRK@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
MMS3_k127_3313783_2	479434.Sthe_1053	6.238e-78	264.0	COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi,27YA8@189775|Thermomicrobia	189775|Thermomicrobia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
MMS3_k127_3313783_5	309801.trd_0969	2.09e-53	190.0	COG0256@1|root,COG0256@2|Bacteria,2G6Y4@200795|Chloroflexi,27YG4@189775|Thermomicrobia	189775|Thermomicrobia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
MMS3_k127_3313783_1	479434.Sthe_1051	3.413e-83	279.0	COG0097@1|root,COG0097@2|Bacteria,2G6HZ@200795|Chloroflexi,27Y65@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
MMS3_k127_3313783_4	479434.Sthe_1050	8.301e-60	209.0	COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi,27YFX@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
MMS3_k127_3313783_8	479434.Sthe_1049	1.227e-24	104.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi	200795|Chloroflexi	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
MMS3_k127_3313783_6	479434.Sthe_1048	3.131e-34	131.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi,27XMS@189775|Thermomicrobia	189775|Thermomicrobia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
MMS3_k127_3329926_8	479434.Sthe_1686	5.533e-71	247.0	COG1286@1|root,COG2340@1|root,COG1286@2|Bacteria,COG2340@2|Bacteria,2G7IY@200795|Chloroflexi	200795|Chloroflexi	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
MMS3_k127_3329926_3	479434.Sthe_1687	2.741e-150	481.0	COG1208@1|root,COG1208@2|Bacteria,2G5KH@200795|Chloroflexi,27XSX@189775|Thermomicrobia	189775|Thermomicrobia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_3329926_5	479434.Sthe_1688	5.601e-111	367.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,27Y0Q@189775|Thermomicrobia	189775|Thermomicrobia	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
MMS3_k127_3329926_10	479434.Sthe_1689	1.924e-55	203.0	COG1385@1|root,COG1385@2|Bacteria,2G70G@200795|Chloroflexi,27YEX@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
MMS3_k127_3329926_1	479434.Sthe_1690	3.987e-214	673.0	COG1625@1|root,COG1625@2|Bacteria,2G5XW@200795|Chloroflexi	200795|Chloroflexi	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
MMS3_k127_3329926_12	479434.Sthe_1691	7.507e-16	81.0	COG1872@1|root,COG1872@2|Bacteria,2G9SM@200795|Chloroflexi,27YQ3@189775|Thermomicrobia	189775|Thermomicrobia	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
MMS3_k127_3329926_6	479434.Sthe_1692	4.318e-106	356.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi,27XT0@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3329926_0	1382356.JQMP01000004_gene417	7.268e-266	829.0	COG5479@1|root,COG5479@2|Bacteria,2GBGV@200795|Chloroflexi,27ZD6@189775|Thermomicrobia	189775|Thermomicrobia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
MMS3_k127_3329926_11	1382356.JQMP01000004_gene416	5.819e-53	192.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi,27YBI@189775|Thermomicrobia	189775|Thermomicrobia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMS3_k127_3329926_4	479434.Sthe_1695	1.226e-123	402.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,27Y7S@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
MMS3_k127_3329926_9	485913.Krac_8704	5.464e-68	241.0	28I4Y@1|root,2Z88D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3329926_7	479434.Sthe_1685	4.322e-80	273.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi,27Y7N@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
MMS3_k127_3329926_2	479434.Sthe_1684	3.339e-187	599.0	COG0477@1|root,COG2814@2|Bacteria,2G7PR@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3343452_4	402880.MmarC5_0377	1.377e-08	63.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,23QWX@183939|Methanococci	183939|Methanococci	V	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
MMS3_k127_3343452_0	330084.JNYZ01000043_gene1498	8.778e-100	339.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4E1YW@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_3343452_1	1122609.AUGT01000017_gene831	1.408e-87	299.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,4DPU7@85009|Propionibacteriales	201174|Actinobacteria	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
MMS3_k127_3343452_2	517722.AEUE01000001_gene2840	3.081e-36	148.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2TUZ8@28211|Alphaproteobacteria,2KDGT@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
MMS3_k127_3343452_3	32264.tetur28g02510.1	7.407e-09	57.0	COG1012@1|root,KOG2450@2759|Eukaryota,38CDB@33154|Opisthokonta,3BCJG@33208|Metazoa,3CU6J@33213|Bilateria,41WX8@6656|Arthropoda	33208|Metazoa	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with oxidation-reduction process	ALDH1A2	GO:0000003,GO:0000166,GO:0001101,GO:0001523,GO:0001568,GO:0001654,GO:0001655,GO:0001756,GO:0001758,GO:0001822,GO:0001889,GO:0001936,GO:0001944,GO:0001947,GO:0002009,GO:0002072,GO:0002138,GO:0002237,GO:0003002,GO:0003007,GO:0003143,GO:0003674,GO:0003824,GO:0004028,GO:0004029,GO:0004030,GO:0004745,GO:0005096,GO:0005488,GO:0005497,GO:0005501,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006066,GO:0006067,GO:0006069,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006117,GO:0006629,GO:0006720,GO:0006721,GO:0006766,GO:0006775,GO:0006776,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007275,GO:0007368,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0007494,GO:0007507,GO:0007584,GO:0008047,GO:0008150,GO:0008152,GO:0008284,GO:0008285,GO:0008289,GO:0008299,GO:0008610,GO:0008774,GO:0009055,GO:0009056,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009954,GO:0009987,GO:0009991,GO:0010033,GO:0010468,GO:0010604,GO:0010628,GO:0010817,GO:0010941,GO:0010942,GO:0014031,GO:0014032,GO:0014033,GO:0014070,GO:0014706,GO:0016043,GO:0016052,GO:0016053,GO:0016101,GO:0016102,GO:0016114,GO:0016331,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016918,GO:0016999,GO:0017144,GO:0018479,GO:0019222,GO:0019318,GO:0019320,GO:0019637,GO:0019682,GO:0019752,GO:0019840,GO:0019842,GO:0021510,GO:0021515,GO:0021517,GO:0021522,GO:0021536,GO:0021700,GO:0021915,GO:0021953,GO:0021983,GO:0022008,GO:0022414,GO:0022607,GO:0022900,GO:0023052,GO:0030154,GO:0030182,GO:0030234,GO:0030323,GO:0030324,GO:0030326,GO:0030522,GO:0030695,GO:0030900,GO:0030902,GO:0031016,GO:0031076,GO:0031667,GO:0031974,GO:0031981,GO:0032355,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032526,GO:0032570,GO:0032787,GO:0032870,GO:0033189,GO:0033273,GO:0033574,GO:0033993,GO:0034097,GO:0034308,GO:0034754,GO:0035050,GO:0035094,GO:0035107,GO:0035108,GO:0035113,GO:0035115,GO:0035136,GO:0035239,GO:0035270,GO:0035282,GO:0035295,GO:0035799,GO:0036094,GO:0036296,GO:0042127,GO:0042221,GO:0042445,GO:0042493,GO:0042562,GO:0042572,GO:0042573,GO:0042574,GO:0042698,GO:0042802,GO:0042904,GO:0042905,GO:0042981,GO:0043009,GO:0043010,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043087,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043547,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044849,GO:0045471,GO:0046365,GO:0046394,GO:0046677,GO:0048037,GO:0048048,GO:0048384,GO:0048468,GO:0048471,GO:0048511,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048562,GO:0048565,GO:0048566,GO:0048568,GO:0048592,GO:0048593,GO:0048596,GO:0048598,GO:0048609,GO:0048646,GO:0048699,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048738,GO:0048762,GO:0048799,GO:0048856,GO:0048863,GO:0048864,GO:0048869,GO:0050662,GO:0050678,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0051336,GO:0051345,GO:0051704,GO:0051707,GO:0051716,GO:0055093,GO:0055114,GO:0055123,GO:0060173,GO:0060255,GO:0060322,GO:0060324,GO:0060429,GO:0060485,GO:0060537,GO:0060541,GO:0060548,GO:0060562,GO:0060589,GO:0060900,GO:0061008,GO:0061053,GO:0061371,GO:0061624,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070404,GO:0070482,GO:0070542,GO:0070887,GO:0071229,GO:0071300,GO:0071310,GO:0071396,GO:0071398,GO:0071495,GO:0071695,GO:0071704,GO:0071840,GO:0072001,GO:0072189,GO:0072330,GO:0072358,GO:0072359,GO:0090242,GO:0090596,GO:0097159,GO:0097305,GO:0098772,GO:1901135,GO:1901214,GO:1901215,GO:1901265,GO:1901363,GO:1901575,GO:1901576,GO:1901615,GO:1901654,GO:1901700,GO:1901701	1.2.1.3,1.2.1.36	ko:K00128,ko:K07249	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00830,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00830,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02123,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R08385	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_3347060_10	479434.Sthe_2980	3.632e-20	94.0	COG3881@1|root,COG3881@2|Bacteria,2GBNJ@200795|Chloroflexi,27YD3@189775|Thermomicrobia	189775|Thermomicrobia	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
MMS3_k127_3347060_1	706587.Desti_1932	1.361e-221	700.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6	ko:K01535,ko:K12955	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.24,3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMS3_k127_3347060_11	598659.NAMH_0768	4.954e-10	60.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2YNMM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMS3_k127_3347060_6	658187.LDG_7055	1.719e-81	276.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1JCWM@118969|Legionellales	1236|Gammaproteobacteria	P	E1-E2 ATPase	-	-	-	ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.24	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMS3_k127_3347060_5	479434.Sthe_0347	1.418e-94	315.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi,27XF2@189775|Thermomicrobia	189775|Thermomicrobia	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
MMS3_k127_3347060_2	479434.Sthe_0345	6.853e-173	551.0	COG0552@1|root,COG0552@2|Bacteria,2G63M@200795|Chloroflexi,27XH9@189775|Thermomicrobia	189775|Thermomicrobia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
MMS3_k127_3347060_0	479434.Sthe_0344	1.329e-227	713.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi,27Y15@189775|Thermomicrobia	189775|Thermomicrobia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
MMS3_k127_3347060_4	309801.trd_1817	5.017e-97	329.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
MMS3_k127_3347060_3	309801.trd_1816	3.997e-98	328.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,27YVM@189775|Thermomicrobia	189775|Thermomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_3347060_7	479434.Sthe_0340	9.449e-74	256.0	COG3897@1|root,COG3897@2|Bacteria,2GB9K@200795|Chloroflexi,27YC1@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
MMS3_k127_3347060_9	479434.Sthe_0337	9.307e-24	102.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,27XEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Anticodon-binding domain of tRNA	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
MMS3_k127_335054_1	479434.Sthe_0621	1.379e-82	286.0	COG5401@1|root,COG5401@2|Bacteria,2GA61@200795|Chloroflexi,27Y9M@189775|Thermomicrobia	189775|Thermomicrobia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
MMS3_k127_335054_0	479434.Sthe_0623	6.99e-318	990.0	COG0507@1|root,COG0507@2|Bacteria,2G626@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
MMS3_k127_335054_2	309801.trd_0518	5.043e-27	117.0	2A1UY@1|root,30Q43@2|Bacteria,2GA1F@200795|Chloroflexi,27YMF@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_335054_3	765913.ThidrDRAFT_3967	5.278e-27	112.0	COG3041@1|root,COG3041@2|Bacteria,1NBQC@1224|Proteobacteria,1SE8W@1236|Gammaproteobacteria,1WYWU@135613|Chromatiales	135613|Chromatiales	S	Addiction module toxin RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
MMS3_k127_335054_4	269799.Gmet_0220	1.939e-15	79.0	COG2161@1|root,COG2161@2|Bacteria,1NFVK@1224|Proteobacteria,430TQ@68525|delta/epsilon subdivisions,2WVWU@28221|Deltaproteobacteria,43V3R@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
MMS3_k127_335054_5	1449355.JQNR01000005_gene3890	0.0008146	43.0	COG0741@1|root,COG3209@1|root,COG0741@2|Bacteria,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
MMS3_k127_3359715_2	485913.Krac_2592	5.709e-129	424.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3359715_3	479434.Sthe_0029	7.65e-56	198.0	COG0780@1|root,COG0780@2|Bacteria,2G9AQ@200795|Chloroflexi,27YFT@189775|Thermomicrobia	189775|Thermomicrobia	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
MMS3_k127_3359715_0	479434.Sthe_1794	1.654e-216	676.0	COG1960@1|root,COG1960@2|Bacteria,2G815@200795|Chloroflexi,27Z4U@189775|Thermomicrobia	189775|Thermomicrobia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_3359715_1	479434.Sthe_1793	1.061e-183	582.0	COG1804@1|root,COG1804@2|Bacteria,2G61Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_3359715_4	1385935.N836_03185	4.601e-15	78.0	COG0454@1|root,COG0456@2|Bacteria,1G5GC@1117|Cyanobacteria	1117|Cyanobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
MMS3_k127_3361747_3	525898.Sdel_0310	4.167e-14	81.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,42RN4@68525|delta/epsilon subdivisions,2YPXS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
MMS3_k127_3361747_4	1261545.MBE-HAL_2424	7.719e-05	51.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_3361747_0	667014.Thein_0330	1.315e-110	377.0	COG1055@1|root,COG1055@2|Bacteria,2GGU6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
MMS3_k127_3361747_1	1128421.JAGA01000003_gene3195	4.076e-93	320.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
MMS3_k127_3361747_2	584708.Apau_0170	1.377e-26	115.0	COG1592@1|root,COG1592@2|Bacteria,3TBAS@508458|Synergistetes	508458|Synergistetes	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMS3_k127_3374577_0	349163.Acry_1581	5.823e-243	752.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2TQJW@28211|Alphaproteobacteria,2JPZU@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narZ	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
MMS3_k127_3374577_1	349163.Acry_1582	3.792e-63	218.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2V6FU@28211|Alphaproteobacteria,2JQ7D@204441|Rhodospirillales	204441|Rhodospirillales	C	Nitrate reductase beta subunit	narH	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
MMS3_k127_3384326_4	1445613.JALM01000076_gene184	9.153e-39	151.0	2DBX9@1|root,2ZBN9@2|Bacteria,2I98J@201174|Actinobacteria,4E354@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3384326_0	765698.Mesci_5794	3.579e-191	614.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2U29S@28211|Alphaproteobacteria,43R5B@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	TIGRFAM hydrolase CocE NonD family protein	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_3384326_5	485913.Krac_4389	5.524e-36	140.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K05558,ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
MMS3_k127_3384326_2	479434.Sthe_2360	1.634e-69	244.0	COG1704@1|root,COG1704@2|Bacteria,2G7BN@200795|Chloroflexi,27Z8K@189775|Thermomicrobia	189775|Thermomicrobia	S	E3 Ubiquitin ligase	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
MMS3_k127_3384326_3	649638.Trad_2578	1.985e-46	169.0	COG4977@1|root,COG4977@2|Bacteria,1WMU4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
MMS3_k127_3390767_0	479434.Sthe_2041	2.957e-234	732.0	COG2936@1|root,COG2936@2|Bacteria,2G86S@200795|Chloroflexi	200795|Chloroflexi	S	X-Pro dipeptidyl-peptidase domain protein	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_3390767_1	479434.Sthe_2040	1.076e-193	611.0	COG1804@1|root,COG1804@2|Bacteria,2GB4P@200795|Chloroflexi,27XYZ@189775|Thermomicrobia	189775|Thermomicrobia	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
MMS3_k127_3390767_2	479434.Sthe_1545	4.233e-14	79.0	COG5553@1|root,COG5553@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
MMS3_k127_3396037_4	298655.KI912266_gene3150	3.76e-63	222.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria,4EU0R@85013|Frankiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMS3_k127_3396037_2	309801.trd_1345	1.56e-71	253.0	COG2141@1|root,COG2141@2|Bacteria,2G8CA@200795|Chloroflexi,27Y7R@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3396037_0	479434.Sthe_2097	1.571e-133	432.0	COG1131@1|root,COG1131@2|Bacteria,2G6HN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3396037_1	479434.Sthe_2098	6.965e-95	323.0	COG1668@1|root,COG1668@2|Bacteria,2GA92@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_3401093_14	479434.Sthe_3365	6.509e-32	126.0	COG1131@1|root,COG1131@2|Bacteria,2G6JW@200795|Chloroflexi,27YZ8@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3401093_5	479434.Sthe_3364	2.756e-139	452.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,27Z1H@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_3401093_13	479434.Sthe_3363	3.446e-45	171.0	COG1986@1|root,COG1986@2|Bacteria,2G9K8@200795|Chloroflexi,27Z8U@189775|Thermomicrobia	189775|Thermomicrobia	F	Protein of unknown function DUF84	-	-	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
MMS3_k127_3401093_10	179408.Osc7112_5302	5.738e-87	296.0	COG4106@1|root,COG4106@2|Bacteria,1G3BF@1117|Cyanobacteria,1H983@1150|Oscillatoriales	1117|Cyanobacteria	S	Methyltransferase type 11	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
MMS3_k127_3401093_6	479434.Sthe_3358	7.498e-126	423.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi,27Y67@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3401093_16	479434.Sthe_3357	6.975e-14	78.0	2BQM6@1|root,32JH8@2|Bacteria,2GBC5@200795|Chloroflexi,27YR2@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3401093_11	1303518.CCALI_01127	5.61e-80	274.0	COG2362@1|root,COG2362@2|Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
MMS3_k127_3401093_0	479434.Sthe_2592	2.122e-288	891.0	COG1473@1|root,COG1473@2|Bacteria,2GBCW@200795|Chloroflexi,27YTQ@189775|Thermomicrobia	189775|Thermomicrobia	S	amidohydrolase	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	-
MMS3_k127_3401093_1	485913.Krac_5710	6.707e-212	677.0	COG3533@1|root,COG3533@2|Bacteria,2G7X9@200795|Chloroflexi	200795|Chloroflexi	S	COGs COG3533 conserved	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
MMS3_k127_3401093_4	479434.Sthe_3356	1.155e-139	457.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi,27Z1M@189775|Thermomicrobia	189775|Thermomicrobia	P	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
MMS3_k127_3401093_7	479434.Sthe_3355	4.103e-114	375.0	COG2084@1|root,COG2084@2|Bacteria,2G6B3@200795|Chloroflexi,27Y9G@189775|Thermomicrobia	189775|Thermomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_3401093_3	1382356.JQMP01000001_gene841	2.927e-185	597.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi,27XYA@189775|Thermomicrobia	189775|Thermomicrobia	M	SMART Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
MMS3_k127_3401093_9	479434.Sthe_3350	9.077e-91	310.0	COG1686@1|root,COG1686@2|Bacteria,2G8TU@200795|Chloroflexi,27Y7Z@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
MMS3_k127_3401093_2	479434.Sthe_3347	9.471e-186	604.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
MMS3_k127_3401093_12	479434.Sthe_3345	6.801e-77	261.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YF3@189775|Thermomicrobia	189775|Thermomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3401093_15	1128421.JAGA01000003_gene3734	1.814e-15	86.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
MMS3_k127_3401093_8	479434.Sthe_1896	1.815e-96	319.0	COG4166@1|root,COG4166@2|Bacteria,2G8A0@200795|Chloroflexi,27XKE@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3414595_5	479434.Sthe_0413	7.71e-58	204.0	COG0477@1|root,COG2814@2|Bacteria,2G8SG@200795|Chloroflexi,27XS0@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3414595_9	479434.Sthe_0412	1.541e-30	125.0	COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
MMS3_k127_3414595_6	479434.Sthe_0411	1.815e-57	212.0	2EGIS@1|root,33AAZ@2|Bacteria,2GBQ2@200795|Chloroflexi,27YMU@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3414595_11	479434.Sthe_0410	1.626e-23	104.0	COG0762@1|root,COG0762@2|Bacteria,2G9QH@200795|Chloroflexi,27YQI@189775|Thermomicrobia	189775|Thermomicrobia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
MMS3_k127_3414595_2	479434.Sthe_0409	8.18e-141	453.0	COG1052@1|root,COG1052@2|Bacteria,2G9ZY@200795|Chloroflexi,27Y18@189775|Thermomicrobia	189775|Thermomicrobia	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_3414595_1	479434.Sthe_0408	3.01e-166	528.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,27XWX@189775|Thermomicrobia	189775|Thermomicrobia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
MMS3_k127_3414595_3	479434.Sthe_0397	2.886e-70	241.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi,27YCQ@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMS3_k127_3414595_0	1382356.JQMP01000004_gene640	1.829e-173	552.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,27XYX@189775|Thermomicrobia	189775|Thermomicrobia	E	Beta-eliminating lyase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
MMS3_k127_3414595_7	479434.Sthe_0393	1.954e-53	196.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi,27YIN@189775|Thermomicrobia	189775|Thermomicrobia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
MMS3_k127_3414595_4	479434.Sthe_0392	3.479e-58	210.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi,27YPU@189775|Thermomicrobia	189775|Thermomicrobia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
MMS3_k127_3414595_8	479434.Sthe_0391	2.514e-41	158.0	COG1418@1|root,COG1418@2|Bacteria,2G7CI@200795|Chloroflexi	200795|Chloroflexi	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3414595_10	479434.Sthe_0390	1.669e-30	122.0	COG1994@1|root,COG1994@2|Bacteria,2G6VM@200795|Chloroflexi,27Y97@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_341588_2	1382356.JQMP01000003_gene2256	4.68e-35	134.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi,27YD6@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein S12/S23	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
MMS3_k127_341588_1	479434.Sthe_1032	4.734e-82	274.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi,27Y66@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
MMS3_k127_341588_0	479434.Sthe_1033	0.0	1183.0	COG0480@1|root,COG0480@2|Bacteria,2G63B@200795|Chloroflexi,27XU6@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_341588_3	479434.Sthe_1611	1.871e-29	118.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMS3_k127_3434404_1	479434.Sthe_0069	1.044e-80	273.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Nitroreductase
MMS3_k127_3434404_3	502558.EGYY_11110	9.763e-44	171.0	COG1131@1|root,COG1131@2|Bacteria,2IJGC@201174|Actinobacteria,4CVUS@84998|Coriobacteriia	84998|Coriobacteriia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3434404_4	479437.Elen_1174	4.542e-20	105.0	2B1F3@1|root,31TVT@2|Bacteria,2HV8S@201174|Actinobacteria,4CWHD@84998|Coriobacteriia	84998|Coriobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3434404_2	1382356.JQMP01000004_gene117	2.445e-75	263.0	COG0860@1|root,COG0860@2|Bacteria,2G9MY@200795|Chloroflexi,27Z4E@189775|Thermomicrobia	189775|Thermomicrobia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
MMS3_k127_3434404_5	643648.Slip_1962	1.009e-17	89.0	COG1487@1|root,COG1487@2|Bacteria,1VKMK@1239|Firmicutes,24V7P@186801|Clostridia	186801|Clostridia	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
MMS3_k127_3434404_6	1089553.Tph_c02460	6.094e-05	49.0	2C4PN@1|root,330XG@2|Bacteria,1VGPV@1239|Firmicutes,24TN4@186801|Clostridia,42IRT@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3434404_0	479434.Sthe_2042	1.273e-161	518.0	COG0389@1|root,COG0389@2|Bacteria,2G6I6@200795|Chloroflexi,27YX5@189775|Thermomicrobia	189775|Thermomicrobia	L	impB/mucB/samB family	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
MMS3_k127_34377_7	1382356.JQMP01000003_gene1773	1.329e-101	342.0	COG1680@1|root,COG1680@2|Bacteria,2GBDK@200795|Chloroflexi,27YYY@189775|Thermomicrobia	189775|Thermomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_34377_4	1128421.JAGA01000002_gene1080	1.727e-132	435.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
MMS3_k127_34377_8	1380394.JADL01000009_gene3201	2.141e-62	228.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,2TRVI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	succinylglutamate desuccinylase	doeB	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
MMS3_k127_34377_3	105420.BBPO01000004_gene1423	7.425e-144	466.0	COG1840@1|root,COG1840@2|Bacteria,2HN57@201174|Actinobacteria,2NHAS@228398|Streptacidiphilus	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
MMS3_k127_34377_2	105420.BBPO01000004_gene1422	7.384e-155	507.0	COG1178@1|root,COG1178@2|Bacteria,2IN5Y@201174|Actinobacteria,2NGNA@228398|Streptacidiphilus	201174|Actinobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
MMS3_k127_34377_6	436229.JOEH01000045_gene7429	4.158e-111	374.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,2NGTR@228398|Streptacidiphilus	201174|Actinobacteria	E	TOBE domain	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
MMS3_k127_34377_5	1382356.JQMP01000004_gene503	3.45e-116	387.0	COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia	189775|Thermomicrobia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_34377_0	479434.Sthe_0081	0.0	1197.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,27Y2U@189775|Thermomicrobia	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMS3_k127_34377_1	479434.Sthe_0083	0.0	1116.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi,27XPX@189775|Thermomicrobia	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	-	-	-	-	-	-	-	-	-	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMS3_k127_3449714_2	485913.Krac_10690	2.392e-06	58.0	29BBV@1|root,2ZCHD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
MMS3_k127_3449714_1	479434.Sthe_2695	6.391e-97	336.0	COG5001@1|root,COG5001@2|Bacteria,2G7UT@200795|Chloroflexi,27Y1B@189775|Thermomicrobia	189775|Thermomicrobia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
MMS3_k127_3449714_0	1500897.JQNA01000002_gene1522	4.508e-104	343.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VNZQ@28216|Betaproteobacteria,1KGKU@119060|Burkholderiaceae	28216|Betaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
MMS3_k127_3458496_5	1120950.KB892804_gene1476	3.843e-33	136.0	2EBG5@1|root,335GQ@2|Bacteria,2GRUT@201174|Actinobacteria,4DSMC@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3458496_0	485913.Krac_6444	5.19e-111	374.0	COG0642@1|root,COG2205@2|Bacteria	485913.Krac_6444|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3458496_1	485913.Krac_6443	5.166e-105	344.0	COG0745@1|root,COG0745@2|Bacteria	485913.Krac_6443|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3458496_6	1206720.BAFQ01000288_gene6122	2.106e-09	63.0	COG0654@1|root,COG0654@2|Bacteria,2GIZU@201174|Actinobacteria,4FVVJ@85025|Nocardiaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	1.14.13.1,1.14.13.218	ko:K00480,ko:K20940	ko00405,ko00621,ko00624,ko00626,ko01100,ko01120,ko01130,ko01220,map00405,map00621,map00624,map00626,map01100,map01120,map01130,map01220	M00835	R00818,R05632,R06915,R06936,R06939	RC00389	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
MMS3_k127_3458496_4	1340493.JNIF01000003_gene2933	1.266e-42	160.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMS3_k127_3458496_3	653045.Strvi_5339	4.632e-89	302.0	COG0500@1|root,COG2226@2|Bacteria,2GKH6@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_3458496_2	196162.Noca_4966	1.897e-91	325.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_3460918_1	485913.Krac_1243	8.825e-26	108.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	ynjA	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	CMD
MMS3_k127_3460918_2	485913.Krac_1243	1.505e-25	109.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	ynjA	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	CMD
MMS3_k127_3460918_0	1382356.JQMP01000003_gene2029	4.374e-162	526.0	COG1840@1|root,COG1840@2|Bacteria,2GBNE@200795|Chloroflexi,27XNQ@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3460918_3	1403313.AXBR01000022_gene2785	2.316e-20	93.0	COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HD73@91061|Bacilli,1ZBNG@1386|Bacillus	91061|Bacilli	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
MMS3_k127_3461198_4	479434.Sthe_1250	6.325e-22	96.0	COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,27YMZ@189775|Thermomicrobia	189775|Thermomicrobia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
MMS3_k127_3461198_3	479434.Sthe_1251	1.252e-93	314.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi,27Y7X@189775|Thermomicrobia	189775|Thermomicrobia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
MMS3_k127_3461198_2	479434.Sthe_1252	6.089e-159	509.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi,27XWV@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
MMS3_k127_3461198_1	479434.Sthe_1253	2.702e-181	571.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi,27Y38@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
MMS3_k127_3461198_0	479434.Sthe_1254	1.189e-214	674.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi,27XU0@189775|Thermomicrobia	189775|Thermomicrobia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
MMS3_k127_3476523_6	479434.Sthe_2350	6.251e-17	89.0	COG0823@1|root,COG0823@2|Bacteria,2GBFZ@200795|Chloroflexi,27ZCM@189775|Thermomicrobia	189775|Thermomicrobia	U	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3476523_5	485913.Krac_5622	6.023e-38	147.0	COG5207@1|root,COG5207@2|Bacteria	2|Bacteria	O	Pfam Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
MMS3_k127_3476523_1	1382306.JNIM01000001_gene487	4.219e-153	495.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
MMS3_k127_3476523_3	1288963.ADIS_3902	1.393e-75	263.0	COG1028@1|root,COG1028@2|Bacteria,4NFU6@976|Bacteroidetes,47KT7@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_3476523_2	1445613.JALM01000120_gene1492	7.231e-121	394.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4DYUZ@85010|Pseudonocardiales	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
MMS3_k127_3476523_0	479434.Sthe_1507	1.917e-175	561.0	COG0477@1|root,COG2814@2|Bacteria,2G8DX@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3476523_4	1128421.JAGA01000004_gene2704	8.653e-67	239.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
MMS3_k127_3491469_6	479434.Sthe_1740	4.696e-99	329.0	COG0743@1|root,COG0743@2|Bacteria,2G5RB@200795|Chloroflexi,27Y4B@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
MMS3_k127_3491469_7	479434.Sthe_0523	7.807e-52	192.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi,27YJE@189775|Thermomicrobia	189775|Thermomicrobia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
MMS3_k127_3491469_8	479434.Sthe_0522	6.375e-37	143.0	COG1430@1|root,COG1430@2|Bacteria,2G794@200795|Chloroflexi,27YP7@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
MMS3_k127_3491469_4	479434.Sthe_0521	5.172e-112	369.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi,27XSY@189775|Thermomicrobia	189775|Thermomicrobia	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
MMS3_k127_3491469_3	479434.Sthe_0520	7.156e-127	413.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi,27XX2@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
MMS3_k127_3491469_1	479434.Sthe_0519	5.104e-258	801.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
MMS3_k127_3491469_2	479434.Sthe_0518	5.404e-166	532.0	COG2201@1|root,COG4963@1|root,COG2201@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,27XZZ@189775|Thermomicrobia	189775|Thermomicrobia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
MMS3_k127_3491469_5	479434.Sthe_0517	1.834e-99	334.0	COG3745@1|root,COG3745@2|Bacteria,2G7H3@200795|Chloroflexi,27XF4@189775|Thermomicrobia	189775|Thermomicrobia	U	SAF	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
MMS3_k127_3491469_0	479434.Sthe_0516	5.193e-286	897.0	COG0417@1|root,COG0417@2|Bacteria,2G7ZM@200795|Chloroflexi	200795|Chloroflexi	L	SMART DNA-directed DNA polymerase B	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B,DNA_pol_B_exo1
MMS3_k127_3498357_0	479434.Sthe_1553	0.0	1123.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi,27XQS@189775|Thermomicrobia	189775|Thermomicrobia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
MMS3_k127_3498357_4	479434.Sthe_1554	2.105e-42	157.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi,27YK2@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal_S15	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
MMS3_k127_3498357_1	479434.Sthe_1555	1.491e-185	583.0	COG0059@1|root,COG0059@2|Bacteria,2G5NP@200795|Chloroflexi,27XV8@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
MMS3_k127_3498357_3	479434.Sthe_1556	2.574e-81	275.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi,27Y6I@189775|Thermomicrobia	189775|Thermomicrobia	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
MMS3_k127_3498357_2	479434.Sthe_1557	2.948e-164	521.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,27XQ6@189775|Thermomicrobia	189775|Thermomicrobia	H	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_3514293_0	926560.KE387023_gene2049	1.697e-104	368.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
MMS3_k127_3516562_6	28444.JODQ01000006_gene672	0.0001425	47.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4EGQA@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_3516562_3	1123508.JH636441_gene3458	4.414e-15	86.0	COG0842@1|root,COG0842@2|Bacteria,2J2NH@203682|Planctomycetes	203682|Planctomycetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
MMS3_k127_3516562_4	479434.Sthe_0692	5.145e-13	79.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_3516562_2	479434.Sthe_2145	6.565e-75	267.0	COG2211@1|root,COG2211@2|Bacteria,2G7ZY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3516562_1	479434.Sthe_2145	7.594e-79	280.0	COG2211@1|root,COG2211@2|Bacteria,2G7ZY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3516562_5	1514668.JOOA01000001_gene285	6.24e-06	57.0	COG0454@1|root,COG0454@2|Bacteria,1V78S@1239|Firmicutes,24G27@186801|Clostridia	186801|Clostridia	K	Acetyltransferase GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
MMS3_k127_3516562_0	485913.Krac_10558	2.1e-144	474.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
MMS3_k127_3522560_9	309801.trd_1593	4.65e-29	121.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,2G6JZ@200795|Chloroflexi,27XJJ@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
MMS3_k127_3522560_7	479434.Sthe_0661	1.543e-103	349.0	COG1216@1|root,COG1216@2|Bacteria,2G8DR@200795|Chloroflexi,27XHV@189775|Thermomicrobia	189775|Thermomicrobia	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
MMS3_k127_3522560_8	479434.Sthe_0660	1.377e-72	254.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi,27YSP@189775|Thermomicrobia	189775|Thermomicrobia	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
MMS3_k127_3522560_4	479434.Sthe_0659	6.954e-129	420.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi,27Y5T@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
MMS3_k127_3522560_10	479434.Sthe_0658	3.129e-17	91.0	COG1774@1|root,COG1774@2|Bacteria,2GBCE@200795|Chloroflexi,27YRN@189775|Thermomicrobia	189775|Thermomicrobia	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3522560_1	479434.Sthe_0656	2.031e-211	683.0	COG0631@1|root,COG0631@2|Bacteria,2G72P@200795|Chloroflexi,27XJ8@189775|Thermomicrobia	189775|Thermomicrobia	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3522560_0	479434.Sthe_0655	2.184e-253	799.0	COG0457@1|root,COG0457@2|Bacteria,2GB7U@200795|Chloroflexi,27XW1@189775|Thermomicrobia	189775|Thermomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
MMS3_k127_3522560_3	479434.Sthe_0654	6.833e-149	483.0	COG1171@1|root,COG1171@2|Bacteria,2G5YN@200795|Chloroflexi,27XYI@189775|Thermomicrobia	189775|Thermomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_3522560_6	479434.Sthe_0653	4.768e-106	352.0	COG0284@1|root,COG0284@2|Bacteria,2G692@200795|Chloroflexi,27XX0@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
MMS3_k127_3522560_2	1382356.JQMP01000003_gene2196	1.243e-175	562.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,27Z82@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3522560_5	1382356.JQMP01000003_gene2195	1.462e-106	351.0	COG1116@1|root,COG1116@2|Bacteria,2G6BU@200795|Chloroflexi,27YRQ@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
MMS3_k127_3522560_11	450851.PHZ_c2704	1.436e-05	49.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2TSP5@28211|Alphaproteobacteria,2KG0E@204458|Caulobacterales	204458|Caulobacterales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
MMS3_k127_3534023_1	479434.Sthe_1462	4.692e-210	668.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi,27Y2G@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3534023_0	479434.Sthe_1462	4.947e-239	757.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi,27Y2G@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3534343_1	485913.Krac_11339	1.715e-27	121.0	2FEK6@1|root,346JM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3534343_2	485913.Krac_11339	2.13e-15	90.0	2FEK6@1|root,346JM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3534343_0	383372.Rcas_1915	3.475e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,2GB53@200795|Chloroflexi,377AG@32061|Chloroflexia	32061|Chloroflexia	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3550286_7	479434.Sthe_1672	1.809e-14	76.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
MMS3_k127_3550286_0	479434.Sthe_1670	0.0	1123.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi,27XEM@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
MMS3_k127_3550286_4	479434.Sthe_1669	5.998e-174	552.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi,27XFG@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
MMS3_k127_3550286_2	479434.Sthe_1667	9.683e-208	654.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi,27Y41@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMS3_k127_3550286_1	479434.Sthe_1664	7.564e-242	757.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi,27Y1N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
MMS3_k127_3550286_5	479434.Sthe_1663	3.128e-122	408.0	COG3359@1|root,COG3359@2|Bacteria	2|Bacteria	L	RNase_H superfamily	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
MMS3_k127_3550286_3	479434.Sthe_1662	7.191e-180	571.0	COG0473@1|root,COG0473@2|Bacteria,2GAQN@200795|Chloroflexi,27XMV@189775|Thermomicrobia	189775|Thermomicrobia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41,1.1.1.42	ko:K00030,ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R00709,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMS3_k127_3550286_6	479434.Sthe_1611	4.979e-30	121.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMS3_k127_355176_2	1382356.JQMP01000003_gene1637	3.153e-93	314.0	COG0726@1|root,COG0726@2|Bacteria,2GA3J@200795|Chloroflexi,27Z0S@189775|Thermomicrobia	189775|Thermomicrobia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_355176_3	479434.Sthe_1011	5.776e-86	291.0	COG2220@1|root,COG2220@2|Bacteria,2GBQC@200795|Chloroflexi,27YVZ@189775|Thermomicrobia	189775|Thermomicrobia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
MMS3_k127_355176_6	479434.Sthe_1013	9.508e-50	179.0	COG3870@1|root,COG3870@2|Bacteria	2|Bacteria	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
MMS3_k127_355176_7	1382356.JQMP01000003_gene2387	4.068e-29	119.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi,27YJS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_355176_5	479434.Sthe_1016	1.406e-60	216.0	COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi,27Y9U@189775|Thermomicrobia	189775|Thermomicrobia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
MMS3_k127_355176_1	479434.Sthe_1017	1.482e-102	340.0	COG1912@1|root,COG1912@2|Bacteria,2G6NI@200795|Chloroflexi,27Y5I@189775|Thermomicrobia	189775|Thermomicrobia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
MMS3_k127_355176_4	479434.Sthe_1019	1.339e-76	266.0	COG0457@1|root,COG0457@2|Bacteria,2G6Q2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2
MMS3_k127_355176_0	479434.Sthe_1020	2.45e-219	688.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi,27Y2T@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
MMS3_k127_355176_8	309801.trd_0353	4.185e-17	91.0	2BQKE@1|root,32JGF@2|Bacteria,2GBAE@200795|Chloroflexi,27YI2@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3578297_0	926569.ANT_19690	3.529e-155	503.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3578297_1	479434.Sthe_3204	5.672e-137	445.0	COG0167@1|root,COG0167@2|Bacteria,2GBTE@200795|Chloroflexi,27Y32@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMS3_k127_3578297_7	316274.Haur_4170	7.225e-05	51.0	COG4283@1|root,COG4283@2|Bacteria,2G9ST@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
MMS3_k127_3578297_4	479434.Sthe_3203	5.002e-108	356.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi,27YS7@189775|Thermomicrobia	189775|Thermomicrobia	Q	Domain of unknown function (DUF2437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
MMS3_k127_3578297_6	3067.XP_002958760.1	3.497e-31	130.0	COG0484@1|root,COG4122@1|root,KOG4188@1|root,KOG0714@2759|Eukaryota,KOG1663@2759|Eukaryota,KOG4188@2759|Eukaryota,37PF2@33090|Viridiplantae,34JJU@3041|Chlorophyta	3041|Chlorophyta	O	Protein of unknown function (DUF3752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3752,DnaJ,Methyltransf_3
MMS3_k127_3578297_5	935840.JAEQ01000016_gene2245	5.027e-45	176.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2TRE1@28211|Alphaproteobacteria,43RAH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMS3_k127_3578297_2	479433.Caci_5085	4.498e-117	385.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria	201174|Actinobacteria	Q	Poly(3-hydroxybutyrate) depolymerase	lpqP	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
MMS3_k127_3578297_3	1379270.AUXF01000005_gene756	4.897e-116	379.0	COG0673@1|root,COG0673@2|Bacteria,1ZU84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_3583516_5	479434.Sthe_0983	5.157e-10	63.0	COG1878@1|root,COG1878@2|Bacteria	2|Bacteria	S	arylformamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMS3_k127_3583516_3	1382356.JQMP01000003_gene2349	2.156e-12	72.0	29M00@1|root,307XG@2|Bacteria,2GBFG@200795|Chloroflexi,27ZAR@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3583516_2	479434.Sthe_0984	1.625e-72	249.0	COG1673@1|root,COG1673@2|Bacteria,2G9JU@200795|Chloroflexi,27Y95@189775|Thermomicrobia	189775|Thermomicrobia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
MMS3_k127_3583516_0	309801.trd_0260	1.232e-225	708.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi,27XF8@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_3583516_1	479434.Sthe_0986	2.896e-107	362.0	COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi,27XX4@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
MMS3_k127_3583516_4	309801.trd_0262	5.507e-11	66.0	COG0247@1|root,COG0247@2|Bacteria,2G5V8@200795|Chloroflexi,27XTC@189775|Thermomicrobia	189775|Thermomicrobia	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
MMS3_k127_3583912_4	1120971.AUCA01000015_gene289	1.104e-35	145.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
MMS3_k127_3583912_1	1382356.JQMP01000004_gene528	1.084e-124	420.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	189775|Thermomicrobia	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3583912_0	485913.Krac_2295	2.453e-151	486.0	COG4447@1|root,COG4447@2|Bacteria,2G8DW@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3583912_2	485913.Krac_4389	3.43e-40	154.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K05558,ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
MMS3_k127_3583912_3	1120948.KB903227_gene4850	2.962e-38	146.0	COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4E71U@85010|Pseudonocardiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
MMS3_k127_3583912_5	525904.Tter_2143	1.568e-08	56.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
MMS3_k127_3585396_1	479434.Sthe_1528	5.962e-80	276.0	COG0726@1|root,COG0726@2|Bacteria,2G76U@200795|Chloroflexi,27Z4V@189775|Thermomicrobia	189775|Thermomicrobia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_3585396_0	479434.Sthe_1949	5.39e-245	762.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,27ZCY@189775|Thermomicrobia	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3585396_2	479434.Sthe_1950	1.125e-41	155.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_3585787_2	479434.Sthe_2676	3.056e-172	549.0	COG0301@1|root,COG0301@2|Bacteria,2GB81@200795|Chloroflexi,27XX8@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
MMS3_k127_3585787_6	309801.trd_A0420	2.053e-14	74.0	COG3526@1|root,COG3526@2|Bacteria,2GA5K@200795|Chloroflexi,27ZBE@189775|Thermomicrobia	189775|Thermomicrobia	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
MMS3_k127_3585787_1	309801.trd_A0414	2.225e-178	570.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,27XET@189775|Thermomicrobia	189775|Thermomicrobia	E	ACT domain	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
MMS3_k127_3585787_0	1009370.ALO_03116	1.024e-216	700.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,4H23V@909932|Negativicutes	909932|Negativicutes	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
MMS3_k127_3585787_5	479434.Sthe_3313	1.316e-25	113.0	2A4CF@1|root,30SY3@2|Bacteria,2G9F0@200795|Chloroflexi,27YGU@189775|Thermomicrobia	189775|Thermomicrobia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
MMS3_k127_3585787_4	479434.Sthe_1822	6.405e-98	336.0	COG0154@1|root,COG0154@2|Bacteria,2G82J@200795|Chloroflexi,27XKT@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_3585787_9	391587.KAOT1_05397	0.0007364	48.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1I30V@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_3585787_3	479434.Sthe_1128	4.96e-125	411.0	COG0446@1|root,COG0446@2|Bacteria,2G6GM@200795|Chloroflexi,27XNV@189775|Thermomicrobia	189775|Thermomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_3588627_6	67356.KL575586_gene549	0.0001134	46.0	COG0001@1|root,COG0001@2|Bacteria,2IGHW@201174|Actinobacteria	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_3588627_4	479434.Sthe_0773	1.001e-26	114.0	COG1961@1|root,COG1961@2|Bacteria,2GA1Z@200795|Chloroflexi,27YQ8@189775|Thermomicrobia	189775|Thermomicrobia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
MMS3_k127_3588627_1	479434.Sthe_0775	7.318e-106	361.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi,27XGD@189775|Thermomicrobia	189775|Thermomicrobia	DF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS_C
MMS3_k127_3588627_2	479434.Sthe_0776	7.283e-81	273.0	COG0634@1|root,COG0634@2|Bacteria	2|Bacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
MMS3_k127_3588627_0	1382356.JQMP01000003_gene2325	0.0	1013.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi,27XT6@189775|Thermomicrobia	189775|Thermomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
MMS3_k127_3588627_5	479434.Sthe_0778	6.585e-20	96.0	2A4RP@1|root,30TD3@2|Bacteria,2GA1P@200795|Chloroflexi,27YNX@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3600179_0	396588.Tgr7_0171	5.583e-154	521.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,Response_reg
MMS3_k127_3603220_11	485913.Krac_9866	1.129e-63	230.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3603220_10	1380390.JIAT01000009_gene896	3.559e-69	243.0	COG0179@1|root,COG0684@1|root,COG0179@2|Bacteria,COG0684@2|Bacteria,2GN1K@201174|Actinobacteria,4CPUK@84995|Rubrobacteria	84995|Rubrobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase,RraA-like
MMS3_k127_3603220_2	1120956.JHZK01000002_gene1009	3.181e-124	422.0	28JZQ@1|root,2Z9PN@2|Bacteria,1N2WN@1224|Proteobacteria,2U0QD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3603220_12	479434.Sthe_1339	3.766e-58	205.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
MMS3_k127_3603220_5	479434.Sthe_2303	3.624e-91	313.0	COG4447@1|root,COG4447@2|Bacteria,2G98Q@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3603220_3	479434.Sthe_2302	3.675e-119	402.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
MMS3_k127_3603220_4	479434.Sthe_2300	1.215e-103	341.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi,27XS2@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the dCTP deaminase family	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
MMS3_k127_3603220_8	479434.Sthe_2298	1.385e-82	278.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,27Y88@189775|Thermomicrobia	189775|Thermomicrobia	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
MMS3_k127_3603220_1	479434.Sthe_1923	6.455e-143	462.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	DUF3500
MMS3_k127_3603220_9	1007103.AFHW01000025_gene338	2.278e-80	276.0	COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,26Y28@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
MMS3_k127_3603220_6	1408418.JNJH01000006_gene1284	3.406e-84	292.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	cysP	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306,ko:K16331	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.4	-	-	PHO4
MMS3_k127_3603220_13	485913.Krac_4276	3.942e-39	154.0	COG1801@1|root,COG1801@2|Bacteria,2G721@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMS3_k127_3603220_14	485913.Krac_4276	2.095e-06	50.0	COG1801@1|root,COG1801@2|Bacteria,2G721@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMS3_k127_3603220_0	479434.Sthe_2294	0.0	1500.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,27XZV@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
MMS3_k127_3603220_7	1499967.BAYZ01000190_gene3834	1.604e-83	286.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	ko:K10709	-	-	-	-	ko00000	-	-	-	AP_endonuc_2
MMS3_k127_3604923_2	1304878.AUGD01000003_gene2688	4.89e-05	46.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TRE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_3604923_1	709797.CSIRO_0914	3.737e-21	94.0	28P20@1|root,2ZBY6@2|Bacteria,1RBJ8@1224|Proteobacteria,2V61U@28211|Alphaproteobacteria,3K04Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3604923_0	883080.HMPREF9697_00345	4.885e-74	270.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,2UNZ9@28211|Alphaproteobacteria,3K2C1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	PT	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp,cNMP_binding
MMS3_k127_3608867_4	1382356.JQMP01000001_gene841	2.269e-33	130.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi,27XYA@189775|Thermomicrobia	189775|Thermomicrobia	M	SMART Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
MMS3_k127_3608867_0	479434.Sthe_3306	8.119e-310	956.0	COG2936@1|root,COG2936@2|Bacteria,2GA38@200795|Chloroflexi,27YZ6@189775|Thermomicrobia	189775|Thermomicrobia	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_3608867_1	479434.Sthe_3305	1.902e-233	734.0	COG0747@1|root,COG0747@2|Bacteria,2G7N5@200795|Chloroflexi,27YWN@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_3608867_2	479434.Sthe_3304	9.92e-153	487.0	COG0601@1|root,COG0601@2|Bacteria,2GBCI@200795|Chloroflexi,27YS8@189775|Thermomicrobia	189775|Thermomicrobia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_3608867_3	479434.Sthe_3303	1.042e-136	439.0	COG1173@1|root,COG1173@2|Bacteria,2GA37@200795|Chloroflexi,27YYH@189775|Thermomicrobia	189775|Thermomicrobia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_3612348_3	379066.GAU_0178	1.485e-88	295.0	COG0610@1|root,COG0610@2|Bacteria	2|Bacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
MMS3_k127_3612348_5	331678.Cphamn1_1035	2.261e-54	197.0	COG1943@1|root,COG1943@2|Bacteria,1FF47@1090|Chlorobi	1090|Chlorobi	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
MMS3_k127_3612348_0	309801.trd_A0613	4.865e-162	522.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi,27YZB@189775|Thermomicrobia	189775|Thermomicrobia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
MMS3_k127_3612348_7	479434.Sthe_3199	2.615e-37	145.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	tadG1	-	-	-	-	-	-	-	-	-	-	-	TadE
MMS3_k127_3612348_8	479434.Sthe_3200	3.07e-33	133.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	tadG1	-	-	-	-	-	-	-	-	-	-	-	TadE
MMS3_k127_3612348_6	479434.Sthe_3202	4.957e-39	147.0	COG4274@1|root,COG4274@2|Bacteria,2GBAJ@200795|Chloroflexi,27YIF@189775|Thermomicrobia	189775|Thermomicrobia	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_3612348_4	1089551.KE386572_gene3286	5.29e-63	225.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2VFPM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3612348_2	1379270.AUXF01000005_gene755	2.159e-116	394.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
MMS3_k127_3612348_1	1379270.AUXF01000005_gene756	3.301e-117	381.0	COG0673@1|root,COG0673@2|Bacteria,1ZU84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_3614814_0	1394178.AWOO02000042_gene8758	6.801e-23	107.0	COG1595@1|root,COG1595@2|Bacteria,2IFHA@201174|Actinobacteria,4EIWZ@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_362802_10	644966.Tmar_1335	1.736e-47	195.0	COG2866@1|root,COG2866@2|Bacteria,1TSIY@1239|Firmicutes,249Z5@186801|Clostridia,3WD0P@538999|Clostridiales incertae sedis	186801|Clostridia	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
MMS3_k127_362802_4	795666.MW7_3395	6.878e-116	396.0	COG0028@1|root,COG0028@2|Bacteria,1R6FF@1224|Proteobacteria,2WF6X@28216|Betaproteobacteria,1KHZB@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_362802_9	479434.Sthe_1832	6.065e-54	198.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMS3_k127_362802_11	1382356.JQMP01000004_gene549	8.334e-36	147.0	COG3173@1|root,COG3173@2|Bacteria,2G7IQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_362802_8	479434.Sthe_2174	1.621e-58	209.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_362802_7	479434.Sthe_2173	4.308e-74	258.0	COG0350@1|root,COG5662@1|root,COG0350@2|Bacteria,COG5662@2|Bacteria,2G98B@200795|Chloroflexi,27Z9T@189775|Thermomicrobia	2|Bacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	cseE	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	zf-HC2
MMS3_k127_362802_1	479434.Sthe_2169	1.194e-184	599.0	COG2979@1|root,COG2979@2|Bacteria,2GBAG@200795|Chloroflexi,27YIA@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF533)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_362802_2	1382306.JNIM01000001_gene1515	2.007e-145	470.0	COG0010@1|root,COG0010@2|Bacteria,2G71U@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_362802_12	1382356.JQMP01000004_gene551	4.988e-20	96.0	2A4M8@1|root,30T82@2|Bacteria,2GB5J@200795|Chloroflexi,27YPN@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_362802_13	309801.trd_0471	3.659e-19	90.0	2A4SJ@1|root,30TDZ@2|Bacteria,2GBCA@200795|Chloroflexi,27YRD@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_362802_5	479434.Sthe_2165	1.054e-74	254.0	COG3303@1|root,COG3303@2|Bacteria,2GBNG@200795|Chloroflexi,27YB3@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMS3_k127_362802_0	479434.Sthe_2164	6.246e-282	884.0	COG0243@1|root,COG0243@2|Bacteria,2G844@200795|Chloroflexi,27XFA@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
MMS3_k127_362802_3	479434.Sthe_2163	1.057e-127	412.0	COG0437@1|root,COG0437@2|Bacteria,2G6C1@200795|Chloroflexi,27XMT@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S binding domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
MMS3_k127_362802_6	479434.Sthe_2162	2.595e-74	254.0	COG5557@1|root,COG5557@2|Bacteria,2GB8R@200795|Chloroflexi,27Y43@189775|Thermomicrobia	189775|Thermomicrobia	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3636703_5	1122182.KB903834_gene5859	2.734e-10	64.0	COG1670@1|root,COG1670@2|Bacteria,2IGQ7@201174|Actinobacteria,4DIUI@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K00663	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_8
MMS3_k127_3636703_0	479434.Sthe_2741	1.451e-209	662.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
MMS3_k127_3636703_3	479434.Sthe_2742	2.702e-127	413.0	COG0494@1|root,COG0537@1|root,COG0494@2|Bacteria,COG0537@2|Bacteria,2G6SB@200795|Chloroflexi,27XKW@189775|Thermomicrobia	189775|Thermomicrobia	FGL	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT,NUDIX
MMS3_k127_3636703_4	479434.Sthe_2743	1.773e-95	325.0	COG2755@1|root,COG2755@2|Bacteria,2G7GQ@200795|Chloroflexi,27YCG@189775|Thermomicrobia	189775|Thermomicrobia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMS3_k127_3636703_1	479434.Sthe_2744	2.832e-166	532.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,27Y28@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
MMS3_k127_3636703_2	479434.Sthe_2604	5.583e-149	481.0	COG0436@1|root,COG0436@2|Bacteria,2GAKE@200795|Chloroflexi,27XZ1@189775|Thermomicrobia	189775|Thermomicrobia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_3653619_2	479434.Sthe_2269	5.644e-71	242.0	COG4748@1|root,COG4748@2|Bacteria	2|Bacteria	NT	type I restriction enzyme	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	AAA_31,HSDR_N,HSDR_N_2
MMS3_k127_3653619_0	479434.Sthe_2448	1.445e-101	343.0	COG0697@1|root,COG0697@2|Bacteria,2G7RS@200795|Chloroflexi,27YZ0@189775|Thermomicrobia	189775|Thermomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMS3_k127_3653619_3	479434.Sthe_2447	2.011e-70	241.0	COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi,27Z4S@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
MMS3_k127_3653619_1	479434.Sthe_2407	6.389e-76	257.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi,27XNU@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
MMS3_k127_3655732_0	926560.KE387023_gene1698	1.255e-90	304.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1WM1W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KOT	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Response_reg
MMS3_k127_3655732_1	118161.KB235922_gene4616	1.987e-89	314.0	COG4191@1|root,COG4191@2|Bacteria,1G1CF@1117|Cyanobacteria,3VNJ2@52604|Pleurocapsales	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
MMS3_k127_3655732_2	330214.NIDE0542	7.625e-32	142.0	COG0745@1|root,COG3829@1|root,COG4191@1|root,COG0745@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
MMS3_k127_366337_0	479434.Sthe_2916	6.301e-155	496.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi,27YZB@189775|Thermomicrobia	189775|Thermomicrobia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
MMS3_k127_366337_3	309801.trd_1014	0.0004981	44.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,2G6KJ@200795|Chloroflexi,27YNQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156,LPG_synthase_TM
MMS3_k127_366337_2	1392490.JHZX01000001_gene1193	1.544e-35	136.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,1I02M@117743|Flavobacteriia	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3664648_4	485913.Krac_9227	2.664e-51	186.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
MMS3_k127_3664648_2	485913.Krac_9228	3.922e-88	297.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
MMS3_k127_3664648_3	324602.Caur_3425	2.63e-77	278.0	COG0248@1|root,COG0248@2|Bacteria,2G776@200795|Chloroflexi,375D9@32061|Chloroflexia	32061|Chloroflexia	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
MMS3_k127_3664648_0	479434.Sthe_0359	1.485e-280	867.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,27XTS@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_3664648_6	673860.AciM339_0691	1.962e-17	90.0	COG0317@1|root,arCOG06870@2157|Archaea	2157|Archaea	KT	HD domain	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
MMS3_k127_3664648_5	479434.Sthe_0361	6.516e-30	120.0	COG2350@1|root,COG2350@2|Bacteria,2GAAH@200795|Chloroflexi,27YI6@189775|Thermomicrobia	189775|Thermomicrobia	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
MMS3_k127_3664648_1	479434.Sthe_0362	1.374e-95	317.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi,27XPS@189775|Thermomicrobia	189775|Thermomicrobia	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
MMS3_k127_3672973_8	479434.Sthe_1361	1.557e-51	186.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi,27XSK@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM alanine racemase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
MMS3_k127_3672973_3	479434.Sthe_1362	1.07e-111	371.0	COG0673@1|root,COG0673@2|Bacteria,2G9C5@200795|Chloroflexi,27ZAV@189775|Thermomicrobia	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	mviM	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMS3_k127_3672973_4	479434.Sthe_1363	3.181e-80	273.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi,27Y8N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
MMS3_k127_3672973_0	479434.Sthe_1364	3.104e-268	834.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G5WB@200795|Chloroflexi,27XQ3@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
MMS3_k127_3672973_1	479434.Sthe_1365	7.684e-164	525.0	COG0151@1|root,COG0151@2|Bacteria,2G5ZE@200795|Chloroflexi,27XZU@189775|Thermomicrobia	189775|Thermomicrobia	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
MMS3_k127_3672973_2	479434.Sthe_1366	1.879e-121	392.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_3672973_5	479434.Sthe_1370	7.76e-60	211.0	COG0494@1|root,COG0494@2|Bacteria,2G7A1@200795|Chloroflexi,27YF6@189775|Thermomicrobia	189775|Thermomicrobia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
MMS3_k127_3672973_6	479434.Sthe_1376	8.577e-57	205.0	COG1670@1|root,COG1670@2|Bacteria,2G9BF@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
MMS3_k127_3672973_7	479434.Sthe_1377	5.704e-53	193.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMS3_k127_3672973_9	1382356.JQMP01000004_gene213	2.735e-38	145.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi,27XVC@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
MMS3_k127_3686238_2	479434.Sthe_0990	1.308e-104	353.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi,27XMN@189775|Thermomicrobia	189775|Thermomicrobia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
MMS3_k127_3686238_0	479434.Sthe_0991	5.26e-223	707.0	COG0433@1|root,COG0433@2|Bacteria,2G62A@200795|Chloroflexi,27XU3@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
MMS3_k127_3686238_1	479434.Sthe_0992	1.206e-185	601.0	COG2203@1|root,COG3605@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3920@2|Bacteria,2G67M@200795|Chloroflexi,27XHF@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_2
MMS3_k127_3686238_3	479434.Sthe_0993	8.112e-84	282.0	COG1028@1|root,COG1028@2|Bacteria,2G8P1@200795|Chloroflexi,27XUC@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3689079_3	479434.Sthe_1109	1.418e-121	399.0	COG0628@1|root,COG0628@2|Bacteria,2G712@200795|Chloroflexi,27Z3Y@189775|Thermomicrobia	189775|Thermomicrobia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMS3_k127_3689079_0	479434.Sthe_1106	8.81e-278	865.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,2G7S3@200795|Chloroflexi,27XKR@189775|Thermomicrobia	189775|Thermomicrobia	I	catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the	-	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMS3_k127_3689079_6	479434.Sthe_1105	4.537e-68	250.0	COG5476@1|root,COG5476@2|Bacteria,2GBCY@200795|Chloroflexi,27YTU@189775|Thermomicrobia	189775|Thermomicrobia	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
MMS3_k127_3689079_7	479434.Sthe_1104	6.745e-66	233.0	COG1877@1|root,COG1877@2|Bacteria,2G6X2@200795|Chloroflexi,27YHH@189775|Thermomicrobia	189775|Thermomicrobia	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
MMS3_k127_3689079_5	479434.Sthe_1103	4.815e-109	371.0	COG0477@1|root,COG2814@2|Bacteria,2G77Q@200795|Chloroflexi,27XS6@189775|Thermomicrobia	189775|Thermomicrobia	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3689079_8	479434.Sthe_1101	2.491e-46	178.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
MMS3_k127_3689079_2	479434.Sthe_1100	1.894e-145	469.0	COG0111@1|root,COG0111@2|Bacteria,2G67B@200795|Chloroflexi,27XG7@189775|Thermomicrobia	2|Bacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_3689079_1	479434.Sthe_1099	2.961e-166	530.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27YWR@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_3689079_9	479434.Sthe_1098	1.617e-31	127.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi,27YNI@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
MMS3_k127_3689079_4	309801.trd_0080	2.957e-117	388.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,27XGG@189775|Thermomicrobia	189775|Thermomicrobia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_37021_0	479434.Sthe_2212	1.118e-229	726.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi,27Y1G@189775|Thermomicrobia	189775|Thermomicrobia	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
MMS3_k127_37021_2	479434.Sthe_2214	2.762e-173	547.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,27Y4E@189775|Thermomicrobia	189775|Thermomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
MMS3_k127_37021_4	309801.trd_1376	1.843e-77	268.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi,27Y8K@189775|Thermomicrobia	189775|Thermomicrobia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
MMS3_k127_37021_5	479434.Sthe_2216	6.811e-48	175.0	2A4QY@1|root,30TC8@2|Bacteria,2GA13@200795|Chloroflexi,27YI3@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_37021_3	479434.Sthe_2217	9.054e-107	351.0	COG2120@1|root,COG2120@2|Bacteria,2G7TK@200795|Chloroflexi,27Z3X@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_37021_1	309801.trd_1890	2.968e-213	676.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi,27XPN@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
MMS3_k127_3718978_3	479434.Sthe_1901	8.023e-72	251.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi,27Y4K@189775|Thermomicrobia	189775|Thermomicrobia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	Methyltransf_31
MMS3_k127_3718978_0	479434.Sthe_1900	1.85e-167	532.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi,27XG3@189775|Thermomicrobia	189775|Thermomicrobia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMS3_k127_3718978_8	479434.Sthe_1899	4.354e-53	193.0	COG1611@1|root,COG1611@2|Bacteria,2G6YH@200795|Chloroflexi,27YEG@189775|Thermomicrobia	189775|Thermomicrobia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMS3_k127_3718978_9	479434.Sthe_1898	2.187e-46	174.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,27YFE@189775|Thermomicrobia	189775|Thermomicrobia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
MMS3_k127_3718978_5	208444.JNYY01000009_gene3563	1.592e-67	243.0	COG2746@1|root,COG2746@2|Bacteria,2IC5T@201174|Actinobacteria	201174|Actinobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
MMS3_k127_3718978_6	479434.Sthe_2145	1.642e-60	225.0	COG2211@1|root,COG2211@2|Bacteria,2G7ZY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3718978_1	309801.trd_0095	7.827e-113	374.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi,27XFH@189775|Thermomicrobia	189775|Thermomicrobia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
MMS3_k127_3718978_4	309801.trd_0096	6.188e-70	242.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi,27Y9Y@189775|Thermomicrobia	189775|Thermomicrobia	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
MMS3_k127_3718978_2	479434.Sthe_1885	4.029e-72	247.0	COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi,27Y7C@189775|Thermomicrobia	189775|Thermomicrobia	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS3_k127_3718978_7	479434.Sthe_1884	8.403e-56	199.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi,27YI5@189775|Thermomicrobia	189775|Thermomicrobia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3725817_12	525904.Tter_0725	2.365e-09	59.0	COG0093@1|root,COG0093@2|Bacteria,2NPCS@2323|unclassified Bacteria	2|Bacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
MMS3_k127_3725817_10	479434.Sthe_1045	1.156e-39	149.0	COG0186@1|root,COG0186@2|Bacteria,2G722@200795|Chloroflexi,27YK1@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
MMS3_k127_3725817_11	479434.Sthe_1044	3.855e-18	87.0	COG0255@1|root,COG0255@2|Bacteria,2GAWF@200795|Chloroflexi,27YQH@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
MMS3_k127_3725817_5	479434.Sthe_1043	4.735e-72	245.0	COG0197@1|root,COG0197@2|Bacteria,2G6NA@200795|Chloroflexi,27Y9W@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
MMS3_k127_3725817_2	479434.Sthe_1042	2.236e-114	372.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi,27XP0@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
MMS3_k127_3725817_7	479434.Sthe_1041	1.581e-48	175.0	COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi,27YKE@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein L22p/L17e	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
MMS3_k127_3725817_8	309801.trd_0980	3.722e-47	170.0	COG0185@1|root,COG0185@2|Bacteria,2G6US@200795|Chloroflexi,27YG8@189775|Thermomicrobia	189775|Thermomicrobia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
MMS3_k127_3725817_1	479434.Sthe_1039	1.143e-143	459.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi,27XVH@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
MMS3_k127_3725817_9	479434.Sthe_1038	9.854e-43	158.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi,27YJ6@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
MMS3_k127_3725817_4	479434.Sthe_1037	1.099e-95	317.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi,27XF6@189775|Thermomicrobia	189775|Thermomicrobia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
MMS3_k127_3725817_3	479434.Sthe_1036	2.549e-106	349.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,27XVD@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
MMS3_k127_3725817_6	479434.Sthe_1035	1.022e-54	194.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi,27YDP@189775|Thermomicrobia	189775|Thermomicrobia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
MMS3_k127_3725817_0	479434.Sthe_1611	6.806e-221	687.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMS3_k127_373368_1	479434.Sthe_0671	6.777e-115	377.0	COG2367@1|root,COG2367@2|Bacteria,2GBEG@200795|Chloroflexi,27Z5G@189775|Thermomicrobia	189775|Thermomicrobia	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMS3_k127_373368_0	479434.Sthe_0670	5.739e-115	383.0	COG0477@1|root,COG2814@2|Bacteria,2G9Z5@200795|Chloroflexi,27XES@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_373368_6	1195236.CTER_3891	5.418e-09	61.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia,3WPWD@541000|Ruminococcaceae	186801|Clostridia	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
MMS3_k127_373368_7	697303.Thewi_0143	6.949e-05	48.0	COG0298@1|root,COG0298@2|Bacteria,1VFE0@1239|Firmicutes,24UXU@186801|Clostridia,42HA3@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
MMS3_k127_373368_3	479434.Sthe_2499	2.085e-103	340.0	29JD5@1|root,306AN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_373368_4	1380355.JNIJ01000009_gene1662	2.362e-68	239.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TUEF@28211|Alphaproteobacteria,3JT5U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	MA20_15005	-	4.1.1.79	ko:K13039	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_373368_5	266779.Meso_1068	3.372e-54	194.0	COG4032@1|root,COG4032@2|Bacteria,1R53S@1224|Proteobacteria,2TT20@28211|Alphaproteobacteria,43K7J@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	MA20_15000	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
MMS3_k127_373368_2	383372.Rcas_1100	1.606e-114	377.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi,374X6@32061|Chloroflexia	32061|Chloroflexia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_3740768_0	479434.Sthe_1378	5.558e-225	705.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi,27XVC@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
MMS3_k127_3740768_6	479434.Sthe_1379	2.413e-56	202.0	2BQKM@1|root,32JGN@2|Bacteria,2GBAT@200795|Chloroflexi,27YK0@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3740768_8	479434.Sthe_1380	2.571e-38	152.0	COG0789@1|root,COG0789@2|Bacteria,2G9V5@200795|Chloroflexi,27ZCT@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMS3_k127_3740768_7	479434.Sthe_1381	3.549e-53	198.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON,LysM
MMS3_k127_3740768_4	479434.Sthe_1382	1e-100	335.0	COG0434@1|root,COG0434@2|Bacteria,2G6UF@200795|Chloroflexi,27Y89@189775|Thermomicrobia	189775|Thermomicrobia	S	BtpA family	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
MMS3_k127_3740768_1	479434.Sthe_1383	5.118e-169	548.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi,27XQQ@189775|Thermomicrobia	189775|Thermomicrobia	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
MMS3_k127_3740768_3	479434.Sthe_1384	5.453e-102	338.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,27YBV@189775|Thermomicrobia	189775|Thermomicrobia	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
MMS3_k127_3740768_5	479434.Sthe_1385	6.722e-85	292.0	COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi,27YAK@189775|Thermomicrobia	189775|Thermomicrobia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
MMS3_k127_3740768_2	479434.Sthe_1386	1.838e-149	481.0	COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi,27XVF@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
MMS3_k127_3740768_9	479434.Sthe_1387	6.164e-11	65.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi,27XX1@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS3_k127_3742131_2	1121877.JQKF01000004_gene1095	0.0003026	49.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
MMS3_k127_3742131_0	479434.Sthe_2141	1.495e-219	714.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	200795|Chloroflexi	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
MMS3_k127_3742131_1	485917.Phep_3798	1.481e-21	107.0	COG5492@1|root,COG5492@2|Bacteria,4PMF3@976|Bacteroidetes,1IT6W@117747|Sphingobacteriia	976|Bacteroidetes	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
MMS3_k127_3745217_2	391037.Sare_4375	6.232e-11	74.0	COG3210@1|root,COG3210@2|Bacteria,2IEG6@201174|Actinobacteria	201174|Actinobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3745217_1	485913.Krac_2597	2.098e-76	262.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_3745217_0	309801.trd_A0788	3.18e-221	701.0	COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi,27YVR@189775|Thermomicrobia	189775|Thermomicrobia	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS3_k127_3746094_1	765910.MARPU_03465	1.003e-42	160.0	COG0500@1|root,COG2226@2|Bacteria,1R5JA@1224|Proteobacteria,1T3U6@1236|Gammaproteobacteria,1X2Q2@135613|Chromatiales	135613|Chromatiales	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family	-	-	2.1.1.156	ko:K18896	ko00260,map00260	-	R10060	RC00003,RC03038	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25
MMS3_k127_3746094_0	349521.HCH_01553	4.1e-88	302.0	COG4850@1|root,COG4850@2|Bacteria,1R3ST@1224|Proteobacteria,1RYC6@1236|Gammaproteobacteria,1XMHT@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
MMS3_k127_3746094_2	694431.DESACE_00250	4.137e-22	98.0	COG4627@1|root,COG4627@2|Bacteria,1RKW8@1224|Proteobacteria,42V7S@68525|delta/epsilon subdivisions,2WRVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_3746948_1	309801.trd_0463	5.476e-98	335.0	COG1233@1|root,COG1233@2|Bacteria,2G5SE@200795|Chloroflexi,27Y46@189775|Thermomicrobia	189775|Thermomicrobia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMS3_k127_3746948_4	1463825.JNXC01000001_gene6024	1.751e-24	114.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4E2HU@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3746948_2	64471.sync_0860	1.072e-94	317.0	COG1028@1|root,COG1028@2|Bacteria,1GPIE@1117|Cyanobacteria,1H3BI@1129|Synechococcus	1117|Cyanobacteria	C	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_3746948_0	479434.Sthe_3255	2.479e-234	732.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	200795|Chloroflexi	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_3746948_3	479434.Sthe_0769	1.059e-36	139.0	COG3858@1|root,COG3858@2|Bacteria,2G7HP@200795|Chloroflexi,27XZM@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycoside hydrolase, family 18	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3752573_3	479434.Sthe_2284	1.895e-68	237.0	COG0111@1|root,COG0637@1|root,COG0111@2|Bacteria,COG0637@2|Bacteria,2G67B@200795|Chloroflexi,27XG7@189775|Thermomicrobia	189775|Thermomicrobia	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
MMS3_k127_3752573_0	479434.Sthe_2284	3.123e-235	745.0	COG0111@1|root,COG0637@1|root,COG0111@2|Bacteria,COG0637@2|Bacteria,2G67B@200795|Chloroflexi,27XG7@189775|Thermomicrobia	189775|Thermomicrobia	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
MMS3_k127_3752573_1	882083.SacmaDRAFT_4330	2.559e-91	309.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4DZDR@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3752573_2	543632.JOJL01000030_gene3485	3.956e-71	248.0	28JAE@1|root,2Z957@2|Bacteria,2I6X1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3752573_4	1394178.AWOO02000003_gene2604	8.124e-17	85.0	COG1309@1|root,COG1309@2|Bacteria,2GKW3@201174|Actinobacteria,4EK3I@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_3755713_6	479434.Sthe_0947	1.09e-72	249.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi,27Y49@189775|Thermomicrobia	189775|Thermomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA,R3H
MMS3_k127_3755713_3	479434.Sthe_0948	1.035e-85	291.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi,27YC6@189775|Thermomicrobia	189775|Thermomicrobia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
MMS3_k127_3755713_8	479434.Sthe_0949	2.947e-55	196.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi,27YHY@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
MMS3_k127_3755713_5	479434.Sthe_0950	6.362e-75	260.0	COG0143@1|root,COG0143@2|Bacteria,2G6VG@200795|Chloroflexi,27Y98@189775|Thermomicrobia	189775|Thermomicrobia	J	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
MMS3_k127_3755713_0	479434.Sthe_0951	1.266e-108	359.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi,27XIP@189775|Thermomicrobia	189775|Thermomicrobia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
MMS3_k127_3755713_1	479434.Sthe_0952	1.24e-93	312.0	COG0800@1|root,COG0800@2|Bacteria,2G8N9@200795|Chloroflexi,27XF9@189775|Thermomicrobia	189775|Thermomicrobia	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
MMS3_k127_3755713_4	479434.Sthe_0953	9.604e-80	274.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi,27YAT@189775|Thermomicrobia	189775|Thermomicrobia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
MMS3_k127_3755713_7	479434.Sthe_0954	2.454e-59	212.0	COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
MMS3_k127_3755713_2	479434.Sthe_0956	3.533e-91	306.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi,27XT6@189775|Thermomicrobia	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
MMS3_k127_3764072_2	1123023.JIAI01000003_gene2709	7.252e-21	97.0	COG2348@1|root,COG2348@2|Bacteria,2I7BS@201174|Actinobacteria,4E9SH@85010|Pseudonocardiales	201174|Actinobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
MMS3_k127_3764072_1	479434.Sthe_2502	1.096e-107	356.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,27XGG@189775|Thermomicrobia	189775|Thermomicrobia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMS3_k127_3766786_5	298654.FraEuI1c_1256	6.125e-05	48.0	COG0463@1|root,COG0463@2|Bacteria,2IG3X@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,PqqD
MMS3_k127_3766786_0	1114856.C496_19525	2.002e-88	301.0	COG2897@1|root,arCOG02019@2157|Archaea,2XW8Q@28890|Euryarchaeota,23UHH@183963|Halobacteria	183963|Halobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
MMS3_k127_3766786_2	1112216.JH594425_gene2685	1.504e-12	68.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2K2F6@204457|Sphingomonadales	204457|Sphingomonadales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
MMS3_k127_3766786_4	696281.Desru_2789	2.684e-06	51.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1TQSP@1239|Firmicutes,249I9@186801|Clostridia	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
MMS3_k127_3766786_3	1131813.AQVT01000001_gene1641	1.318e-11	67.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,1JUUR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
MMS3_k127_3766786_1	399741.Spro_4081	8.152e-22	99.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,402XU@613|Serratia	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
MMS3_k127_3769229_9	398511.BpOF4_05850	1.083e-36	151.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HAXD@91061|Bacilli,1ZQSV@1386|Bacillus	91061|Bacilli	E	Arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_3769229_1	485913.Krac_2911	1.665e-225	721.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2G7G9@200795|Chloroflexi	200795|Chloroflexi	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
MMS3_k127_3769229_10	525904.Tter_1481	4.321e-21	103.0	COG2265@1|root,COG2265@2|Bacteria,2NRDB@2323|unclassified Bacteria	2|Bacteria	J	Methyltransferase domain	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Methyltransf_21,Methyltransf_25,Methyltransf_31
MMS3_k127_3769229_2	479434.Sthe_2064	5.357e-128	415.0	COG2301@1|root,COG2301@2|Bacteria,2G6EA@200795|Chloroflexi,27XJ2@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
MMS3_k127_3769229_4	1265310.CCBD010000030_gene1600	2.958e-110	372.0	COG0154@1|root,COG0154@2|Bacteria,2GN7F@201174|Actinobacteria,235ME@1762|Mycobacteriaceae	201174|Actinobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMS3_k127_3769229_6	479434.Sthe_2563	2.277e-88	303.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_3769229_7	1382356.JQMP01000001_gene956	1.916e-55	203.0	COG2353@1|root,COG2353@2|Bacteria,2G73S@200795|Chloroflexi,27Z4A@189775|Thermomicrobia	189775|Thermomicrobia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
MMS3_k127_3769229_8	1150864.MILUP08_41893	8.245e-52	187.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4DDTU@85008|Micromonosporales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_3769229_0	479434.Sthe_2748	3.561e-254	795.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	2|Bacteria	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_3769229_3	767817.Desgi_2356	6.761e-113	376.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia,2606M@186807|Peptococcaceae	186801|Clostridia	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
MMS3_k127_3769229_5	760568.Desku_1397	7.66e-93	321.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1TT8V@1239|Firmicutes,24BFH@186801|Clostridia,260ZQ@186807|Peptococcaceae	186801|Clostridia	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
MMS3_k127_3770387_4	247490.KSU1_C0597	6.359e-14	76.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
MMS3_k127_3770387_1	309801.trd_A0253	8.574e-100	329.0	COG0461@1|root,COG0461@2|Bacteria,2G7HB@200795|Chloroflexi,27XKH@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
MMS3_k127_3770387_0	479434.Sthe_3030	1.922e-182	582.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi,27Y4Y@189775|Thermomicrobia	189775|Thermomicrobia	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
MMS3_k127_3770387_2	309801.trd_A0258	1.411e-53	198.0	COG0596@1|root,COG0596@2|Bacteria,2G8RV@200795|Chloroflexi,27Z4P@189775|Thermomicrobia	189775|Thermomicrobia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3770387_3	266117.Rxyl_1041	4.173e-41	160.0	COG1670@1|root,COG1670@2|Bacteria,2HP6V@201174|Actinobacteria,4CTRA@84995|Rubrobacteria	84995|Rubrobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_3794635_3	479434.Sthe_1190	1.958e-53	192.0	COG0517@1|root,COG0517@2|Bacteria,2G8Z8@200795|Chloroflexi	200795|Chloroflexi	E	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMS3_k127_3794635_1	479434.Sthe_1191	1.797e-175	566.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi,27XV2@189775|Thermomicrobia	189775|Thermomicrobia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
MMS3_k127_3794635_4	1382356.JQMP01000003_gene2543	2.338e-53	192.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi,27YDS@189775|Thermomicrobia	189775|Thermomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
MMS3_k127_3794635_0	309801.trd_0813	1.21e-210	661.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi,27XRP@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_3794635_5	309801.trd_0812	5.438e-19	91.0	COG1254@1|root,COG1254@2|Bacteria,2G728@200795|Chloroflexi,27YMW@189775|Thermomicrobia	189775|Thermomicrobia	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
MMS3_k127_3794635_2	479434.Sthe_1196	5.13e-152	488.0	COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi,27XPV@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
MMS3_k127_3799186_2	479434.Sthe_1163	7.996e-13	77.0	COG0768@1|root,COG0768@2|Bacteria,2G7V1@200795|Chloroflexi,27XRU@189775|Thermomicrobia	189775|Thermomicrobia	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
MMS3_k127_3799186_0	479434.Sthe_1162	1.267e-185	589.0	COG0772@1|root,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi,27Y4C@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
MMS3_k127_3799186_1	1382356.JQMP01000003_gene2566	2.374e-106	353.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi,27Y3U@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMS3_k127_3803216_1	1038860.AXAP01000055_gene3564	4.146e-117	381.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,3JSY1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_3803216_0	1038860.AXAP01000055_gene3565	3.945e-151	481.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,3JSBS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
MMS3_k127_3803216_2	1120956.JHZK01000022_gene1525	1.137e-71	254.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,1JPVQ@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Cobalamin synthesis protein cobW C-terminal domain	p47K	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
MMS3_k127_3803216_3	1038860.AXAP01000055_gene3563	1.092e-22	98.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3JS1H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
MMS3_k127_3807821_2	479434.Sthe_2654	2.758e-56	216.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZW@200795|Chloroflexi,27YUJ@189775|Thermomicrobia	189775|Thermomicrobia	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMS3_k127_3807821_0	479434.Sthe_0323	3.371e-269	851.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
MMS3_k127_3807821_1	479434.Sthe_0322	2.776e-141	452.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,27XGT@189775|Thermomicrobia	189775|Thermomicrobia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
MMS3_k127_3809247_4	479434.Sthe_1226	1.789e-191	614.0	COG3170@1|root,COG3170@2|Bacteria,2G82N@200795|Chloroflexi,27XRE@189775|Thermomicrobia	189775|Thermomicrobia	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3809247_10	1128421.JAGA01000002_gene1410	6.321e-46	179.0	COG1413@1|root,COG1413@2|Bacteria,2NR83@2323|unclassified Bacteria	2|Bacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
MMS3_k127_3809247_7	1382356.JQMP01000001_gene989	9.65e-103	348.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi,27Z2Y@189775|Thermomicrobia	189775|Thermomicrobia	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
MMS3_k127_3809247_3	479434.Sthe_1224	2.93e-205	651.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi,27Y4T@189775|Thermomicrobia	189775|Thermomicrobia	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMS3_k127_3809247_5	479434.Sthe_1223	1.499e-111	370.0	COG0823@1|root,COG0823@2|Bacteria,2G8Z9@200795|Chloroflexi,27XTF@189775|Thermomicrobia	189775|Thermomicrobia	U	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
MMS3_k127_3809247_1	479434.Sthe_1221	8.252e-308	952.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,27XZT@189775|Thermomicrobia	189775|Thermomicrobia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
MMS3_k127_3809247_6	309801.trd_0852	7.95e-111	374.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi,27XTD@189775|Thermomicrobia	189775|Thermomicrobia	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
MMS3_k127_3809247_0	479434.Sthe_1219	2.69e-321	990.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi,27XM4@189775|Thermomicrobia	189775|Thermomicrobia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
MMS3_k127_3809247_2	479434.Sthe_1218	6.843e-210	666.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi,27XGY@189775|Thermomicrobia	189775|Thermomicrobia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMS3_k127_3809247_11	479434.Sthe_1215	3.844e-30	123.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi,27YPB@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
MMS3_k127_3809247_8	479434.Sthe_1214	2.207e-92	315.0	COG1466@1|root,COG1466@2|Bacteria,2GBAA@200795|Chloroflexi,27YH1@189775|Thermomicrobia	189775|Thermomicrobia	L	dna polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
MMS3_k127_3809247_9	1382356.JQMP01000003_gene2528	4.91e-91	304.0	COG1052@1|root,COG1052@2|Bacteria,2G5K0@200795|Chloroflexi,27XH1@189775|Thermomicrobia	189775|Thermomicrobia	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMS3_k127_3812228_8	479434.Sthe_1080	1.131e-33	134.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_4
MMS3_k127_3812228_3	479434.Sthe_1081	1.65e-118	391.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3812228_5	479434.Sthe_1082	5.184e-96	323.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_3812228_2	479434.Sthe_1083	7.45e-119	392.0	COG1131@1|root,COG1131@2|Bacteria,2G69S@200795|Chloroflexi,27XTG@189775|Thermomicrobia	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3812228_0	479434.Sthe_1084	9.398e-141	452.0	COG0501@1|root,COG0501@2|Bacteria,2G6UV@200795|Chloroflexi,27XQR@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMS3_k127_3812228_6	479434.Sthe_1085	2.954e-73	251.0	arCOG04740@1|root,31PZA@2|Bacteria,2GA0B@200795|Chloroflexi,27Y9E@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3812228_7	479434.Sthe_1086	1.348e-35	137.0	2E3Z4@1|root,32YW2@2|Bacteria,2GA1D@200795|Chloroflexi,27YM3@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3812228_4	479434.Sthe_1087	3.496e-100	331.0	COG1842@1|root,COG1842@2|Bacteria,2G8QB@200795|Chloroflexi,27Y1A@189775|Thermomicrobia	189775|Thermomicrobia	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
MMS3_k127_3812228_1	479434.Sthe_2753	8.255e-123	406.0	COG0451@1|root,COG0451@2|Bacteria,2G74B@200795|Chloroflexi	200795|Chloroflexi	GM	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
MMS3_k127_3815282_1	402777.KB235908_gene140	1.7e-26	116.0	2A3EP@1|root,30RXB@2|Bacteria,1G5P7@1117|Cyanobacteria,1HBVI@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3815282_0	591158.SSMG_05133	3.356e-66	235.0	COG1476@1|root,COG2856@1|root,COG1476@2|Bacteria,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78
MMS3_k127_3831831_6	479434.Sthe_0929	8.327e-95	325.0	COG1657@1|root,COG1657@2|Bacteria,2G8NR@200795|Chloroflexi	200795|Chloroflexi	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
MMS3_k127_3831831_9	1382356.JQMP01000003_gene1947	4.637e-48	183.0	COG1657@1|root,COG1657@2|Bacteria,2G7AD@200795|Chloroflexi,27YE7@189775|Thermomicrobia	189775|Thermomicrobia	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3831831_8	479434.Sthe_0927	1.816e-66	241.0	COG0619@1|root,COG0619@2|Bacteria,2G71W@200795|Chloroflexi,27YHQ@189775|Thermomicrobia	189775|Thermomicrobia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	-
MMS3_k127_3831831_1	479434.Sthe_0926	1.217e-167	549.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,27XTB@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
MMS3_k127_3831831_10	479434.Sthe_0925	5.891e-45	166.0	COG3870@1|root,COG3870@2|Bacteria,2GBAM@200795|Chloroflexi,27YIR@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
MMS3_k127_3831831_0	479434.Sthe_0924	2.7e-190	598.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi,27Y25@189775|Thermomicrobia	189775|Thermomicrobia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	-	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
MMS3_k127_3831831_13	42256.RradSPS_2806	0.0003842	52.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria	201174|Actinobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
MMS3_k127_3831831_4	479434.Sthe_0401	1.713e-124	411.0	COG0665@1|root,COG0665@2|Bacteria,2G6XM@200795|Chloroflexi,27Y4G@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_3831831_2	479434.Sthe_0923	6.625e-144	469.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,2G99E@200795|Chloroflexi,27XPH@189775|Thermomicrobia	189775|Thermomicrobia	MT	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
MMS3_k127_3831831_5	479434.Sthe_0922	2.644e-117	382.0	COG0107@1|root,COG0107@2|Bacteria,2G5Y2@200795|Chloroflexi,27XVT@189775|Thermomicrobia	189775|Thermomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMS3_k127_3831831_3	479434.Sthe_0921	9.602e-125	413.0	COG1196@1|root,COG1196@2|Bacteria,2G9QF@200795|Chloroflexi,27XIX@189775|Thermomicrobia	189775|Thermomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3831831_7	479434.Sthe_0920	8.858e-89	300.0	COG0106@1|root,COG0106@2|Bacteria,2G6EC@200795|Chloroflexi,27YB1@189775|Thermomicrobia	189775|Thermomicrobia	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMS3_k127_3839877_8	479434.Sthe_0498	3.971e-89	300.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi,27YX8@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
MMS3_k127_3839877_13	479434.Sthe_0499	4.624e-34	134.0	COG1734@1|root,COG1734@2|Bacteria,2G7BM@200795|Chloroflexi	200795|Chloroflexi	K	PFAM zinc finger, DksA TraR C4-type	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
MMS3_k127_3839877_12	1382356.JQMP01000003_gene2222	5.982e-45	169.0	COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi,27YJK@189775|Thermomicrobia	189775|Thermomicrobia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
MMS3_k127_3839877_4	479434.Sthe_0501	9.082e-130	422.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,27Y1F@189775|Thermomicrobia	189775|Thermomicrobia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMS3_k127_3839877_5	479434.Sthe_0502	4.126e-124	411.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,27XPR@189775|Thermomicrobia	189775|Thermomicrobia	C	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
MMS3_k127_3839877_1	479434.Sthe_0506	7.503e-196	626.0	COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi,27XKD@189775|Thermomicrobia	189775|Thermomicrobia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3839877_7	479434.Sthe_0508	1.736e-98	330.0	COG1957@1|root,COG1957@2|Bacteria,2G6R6@200795|Chloroflexi,27Y7I@189775|Thermomicrobia	189775|Thermomicrobia	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	ko:K01250	-	-	-	-	ko00000,ko01000	-	-	-	IU_nuc_hydro
MMS3_k127_3839877_10	479434.Sthe_0509	1.346e-70	243.0	COG1484@1|root,COG1484@2|Bacteria,2GA06@200795|Chloroflexi,27Y60@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA-dependent DNA replication	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3839877_3	479434.Sthe_0510	4.346e-138	448.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi,27XMM@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS3_k127_3839877_2	479434.Sthe_0511	1.621e-174	566.0	COG1306@1|root,COG1306@2|Bacteria,2G81Y@200795|Chloroflexi,27XJ9@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4015
MMS3_k127_3839877_6	479434.Sthe_0512	5.143e-107	355.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi,27XG9@189775|Thermomicrobia	189775|Thermomicrobia	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
MMS3_k127_3839877_11	479434.Sthe_0513	1.186e-62	218.0	COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi,27YKK@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
MMS3_k127_3839877_0	479434.Sthe_0514	0.0	1282.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,27XY6@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMS3_k127_3839877_9	479434.Sthe_0515	2.636e-79	273.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi,27YBG@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
MMS3_k127_3843053_7	479434.Sthe_1897	2.102e-45	173.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
MMS3_k127_3843053_2	1380394.JADL01000009_gene3144	1.633e-94	319.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,2JXDQ@204441|Rhodospirillales	204441|Rhodospirillales	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMS3_k127_3843053_11	1382356.JQMP01000004_gene180	4.468e-19	92.0	COG4961@1|root,COG4961@2|Bacteria,2GBBH@200795|Chloroflexi,27YNU@189775|Thermomicrobia	189775|Thermomicrobia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
MMS3_k127_3843053_8	479434.Sthe_0120	1.306e-32	132.0	COG4961@1|root,COG4961@2|Bacteria,2GBBK@200795|Chloroflexi,27YP1@189775|Thermomicrobia	189775|Thermomicrobia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
MMS3_k127_3843053_1	1382356.JQMP01000004_gene178	8.544e-111	376.0	COG4961@1|root,COG4961@2|Bacteria,2GB9G@200795|Chloroflexi,27YAR@189775|Thermomicrobia	189775|Thermomicrobia	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
MMS3_k127_3843053_5	927658.AJUM01000042_gene1494	2.944e-55	207.0	COG2348@1|root,COG2348@2|Bacteria	2|Bacteria	V	transferase activity, transferring amino-acyl groups	-	-	1.14.13.227,1.14.13.236	ko:K15760,ko:K18223	ko00623,ko00640,ko01100,ko01120,ko01220,map00623,map00640,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R10702	RC00269,RC00490,RC03249	ko00000,ko00001,ko00002,ko01000	-	-	-	FemAB,Phenol_Hydrox,YHS
MMS3_k127_3843053_6	1121430.JMLG01000002_gene1060	4.793e-49	185.0	COG4089@1|root,COG4089@2|Bacteria,1V17T@1239|Firmicutes,24D36@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
MMS3_k127_3843053_10	696369.KI912183_gene1779	1.719e-25	117.0	COG3212@1|root,COG3212@2|Bacteria,1VJGF@1239|Firmicutes,24RQ9@186801|Clostridia,262RI@186807|Peptococcaceae	186801|Clostridia	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3843053_13	43759.JNWK01000009_gene5016	7.443e-08	57.0	COG3462@1|root,COG3462@2|Bacteria,2GRGM@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
MMS3_k127_3843053_3	383372.Rcas_2781	3.288e-83	291.0	COG5002@1|root,COG5002@2|Bacteria,2G8BE@200795|Chloroflexi,376H0@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_3843053_4	931627.MycrhDRAFT_2464	2.38e-80	274.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,2346E@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_3843053_0	485913.Krac_4453	1.631e-176	561.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
MMS3_k127_3843053_9	309801.trd_1534	8.696e-31	130.0	COG2010@1|root,COG2010@2|Bacteria,2G9FK@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3843053_12	351160.RCIX2601	1.25e-09	64.0	COG0492@1|root,arCOG01297@2157|Archaea	2157|Archaea	O	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384,ko:K03387	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2
MMS3_k127_3843882_0	485913.Krac_7217	5.941e-131	424.0	COG4260@1|root,COG4260@2|Bacteria	2|Bacteria	N	virion core protein, lumpy skin disease virus	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4428,PrsW-protease
MMS3_k127_3843882_1	309801.trd_A0458	8.71e-88	297.0	COG0647@1|root,COG0647@2|Bacteria,2GA3K@200795|Chloroflexi,27Z1Q@189775|Thermomicrobia	189775|Thermomicrobia	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
MMS3_k127_3843882_2	479434.Sthe_2207	4.856e-80	279.0	COG1712@1|root,COG1712@2|Bacteria	2|Bacteria	S	aspartate dehydrogenase activity	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
MMS3_k127_3843882_3	1547437.LL06_09545	1.214e-14	74.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2TSVI@28211|Alphaproteobacteria,43NY5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.35	ko:K22131	-	-	-	-	ko00000,ko01000	-	-	-	AP_endonuc_2
MMS3_k127_3845718_4	1032480.MLP_52010	6.372e-16	78.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4DVCF@85009|Propionibacteriales	201174|Actinobacteria	L	HTH-like domain	tnp7109-46	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
MMS3_k127_3845718_1	105425.BBPL01000001_gene6318	3.985e-49	183.0	COG0726@1|root,COG0726@2|Bacteria,2H44A@201174|Actinobacteria,2NHIC@228398|Streptacidiphilus	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_3845718_0	1449347.JQLN01000007_gene1374	1.285e-166	557.0	COG1215@1|root,COG1215@2|Bacteria,2I2NS@201174|Actinobacteria,2M44T@2063|Kitasatospora	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_3845718_3	1463887.KL590035_gene7069	6.702e-25	119.0	29WF9@1|root,30I14@2|Bacteria,2IIPX@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_3845718_2	1370121.AUWS01000051_gene1548	5.503e-45	169.0	COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria,236PP@1762|Mycobacteriaceae	201174|Actinobacteria	S	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
MMS3_k127_3848738_2	479434.Sthe_1924	0.0001621	46.0	COG2141@1|root,COG2141@2|Bacteria,2G869@200795|Chloroflexi,27XFF@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3848738_1	479434.Sthe_2145	8.353e-85	297.0	COG2211@1|root,COG2211@2|Bacteria,2G7ZY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3848738_0	479434.Sthe_1925	9.725e-278	860.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,27YWM@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
MMS3_k127_3865758_5	402777.KB235899_gene4871	4.993e-43	162.0	2DM6A@1|root,31WJN@2|Bacteria,1GC51@1117|Cyanobacteria,1HF6K@1150|Oscillatoriales	1117|Cyanobacteria	S	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
MMS3_k127_3865758_4	243230.DR_0987	7.274e-44	168.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_3865758_6	485913.Krac_3333	2.324e-34	153.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_4,PAS_9
MMS3_k127_3865758_9	1463936.JOJI01000007_gene3706	0.0002856	53.0	2DEUK@1|root,2ZPBD@2|Bacteria,2GSEZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3865758_7	485913.Krac_11116	1.37e-30	128.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_3865758_3	1122603.ATVI01000008_gene2289	1.16e-44	170.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,1S3IM@1236|Gammaproteobacteria,1XAJB@135614|Xanthomonadales	135614|Xanthomonadales	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
MMS3_k127_3865758_0	479434.Sthe_2989	2.203e-146	476.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_3865758_2	479434.Sthe_2988	1.183e-59	214.0	COG1896@1|root,COG1896@2|Bacteria,2G72G@200795|Chloroflexi,27YFJ@189775|Thermomicrobia	189775|Thermomicrobia	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
MMS3_k127_3865758_1	479434.Sthe_2987	3.323e-119	389.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi,27XWZ@189775|Thermomicrobia	189775|Thermomicrobia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
MMS3_k127_3865758_8	768710.DesyoDRAFT_1265	6.046e-05	46.0	COG4829@1|root,COG4829@2|Bacteria	2|Bacteria	Q	muconolactone delta-isomerase	-	-	5.3.3.4	ko:K03464	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R06990	RC01109	ko00000,ko00001,ko00002,ko01000	-	-	-	MIase
MMS3_k127_3876185_0	1161401.ASJA01000002_gene2654	1.144e-170	567.0	COG0433@1|root,COG0433@2|Bacteria,1R4SG@1224|Proteobacteria,2U2HY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	TraG-D_C
MMS3_k127_3876185_1	402881.Plav_0314	2.268e-150	482.0	COG0433@1|root,COG0433@2|Bacteria,1N28R@1224|Proteobacteria,2U47U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
MMS3_k127_3877554_7	309801.trd_0950	1.721e-37	146.0	COG1234@1|root,COG1234@2|Bacteria,2GBGY@200795|Chloroflexi,27YCM@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMS3_k127_3877554_1	479434.Sthe_1070	4.984e-94	317.0	COG3191@1|root,COG3191@2|Bacteria,2G6BG@200795|Chloroflexi,27Y1T@189775|Thermomicrobia	189775|Thermomicrobia	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
MMS3_k127_3877554_3	479434.Sthe_1069	6.4e-79	273.0	COG1082@1|root,COG1082@2|Bacteria,2GA0J@200795|Chloroflexi,27YER@189775|Thermomicrobia	189775|Thermomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMS3_k127_3877554_8	543632.JOJL01000012_gene6673	4.804e-11	68.0	COG1917@1|root,COG1917@2|Bacteria,2IRRU@201174|Actinobacteria,4DJUR@85008|Micromonosporales	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3877554_6	479434.Sthe_1068	2.467e-55	196.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi,27YEC@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
MMS3_k127_3877554_4	479434.Sthe_1067	2.909e-67	231.0	COG0102@1|root,COG0102@2|Bacteria,2G6M4@200795|Chloroflexi,27YCR@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
MMS3_k127_3877554_2	479434.Sthe_1066	3.973e-83	283.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi,27YAN@189775|Thermomicrobia	189775|Thermomicrobia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
MMS3_k127_3877554_5	1382356.JQMP01000003_gene2289	4.7e-56	197.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi,27YDE@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
MMS3_k127_3877554_0	479434.Sthe_1064	5.277e-142	455.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi,27XMD@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
MMS3_k127_3880106_5	926550.CLDAP_39900	3.394e-13	77.0	COG3534@1|root,COG3534@2|Bacteria,2G82R@200795|Chloroflexi	200795|Chloroflexi	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
MMS3_k127_3880106_0	479434.Sthe_3398	9.298e-162	518.0	COG0498@1|root,COG0498@2|Bacteria,2G6HK@200795|Chloroflexi,27XIM@189775|Thermomicrobia	189775|Thermomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_3880106_2	479434.Sthe_2987	2.802e-100	334.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi,27XWZ@189775|Thermomicrobia	189775|Thermomicrobia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
MMS3_k127_3880106_4	479434.Sthe_2506	3.051e-49	192.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_3880106_1	525904.Tter_1923	3.824e-112	369.0	COG2084@1|root,COG2084@2|Bacteria,2NQRW@2323|unclassified Bacteria	2|Bacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	glxR	GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMS3_k127_3880106_3	1123504.JQKD01000007_gene3353	2.576e-97	324.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2VJ19@28216|Betaproteobacteria,4ACR0@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the hyi family	hfi	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
MMS3_k127_3881102_4	266265.Bxe_B1769	7.44e-82	287.0	COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,2VPYG@28216|Betaproteobacteria,1JZQX@119060|Burkholderiaceae	28216|Betaproteobacteria	E	fad dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_3881102_0	266117.Rxyl_2783	6.889e-151	509.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,2GIZF@201174|Actinobacteria,4CRHY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
MMS3_k127_3881102_3	642227.HA49_21195	4.985e-103	348.0	COG1473@1|root,COG1473@2|Bacteria,1MXRH@1224|Proteobacteria,1RP0I@1236|Gammaproteobacteria,4BUBD@82986|Tatumella	2|Bacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_3881102_1	1144319.PMI16_00543	6.821e-129	416.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2VPQ8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
MMS3_k127_3881102_2	1123237.Salmuc_03678	7.608e-116	394.0	COG2234@1|root,COG2234@2|Bacteria,1PF4S@1224|Proteobacteria,2U3SU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_3881102_5	208444.JNYY01000001_gene5608	1.74e-51	189.0	COG0778@1|root,COG0778@2|Bacteria,2GPB4@201174|Actinobacteria,4E08E@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMS3_k127_3882010_0	1242864.D187_009276	7.213e-267	830.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,42MR9@68525|delta/epsilon subdivisions,2WIP3@28221|Deltaproteobacteria,2YUNJ@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
MMS3_k127_3888332_4	1120705.FG95_00435	3.037e-07	53.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria,2K0PD@204457|Sphingomonadales	204457|Sphingomonadales	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_3888332_2	1382356.JQMP01000003_gene1512	1.259e-42	160.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	rutC	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
MMS3_k127_3888332_1	1205680.CAKO01000038_gene1601	5.83e-97	337.0	COG0405@1|root,COG0405@2|Bacteria,1R4MM@1224|Proteobacteria,2U1JD@28211|Alphaproteobacteria,2JV5Z@204441|Rhodospirillales	204441|Rhodospirillales	E	Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
MMS3_k127_3888332_0	1382356.JQMP01000003_gene1511	4.578e-119	391.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
MMS3_k127_3888332_3	479434.Sthe_2071	2.56e-14	74.0	COG2141@1|root,COG2141@2|Bacteria,2GA05@200795|Chloroflexi,27Y5V@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3889797_0	479434.Sthe_2060	7.301e-161	514.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi,27XY7@189775|Thermomicrobia	189775|Thermomicrobia	P	TOBE domain	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
MMS3_k127_3889797_2	479434.Sthe_2896	2.616e-93	312.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi,27Y50@189775|Thermomicrobia	200795|Chloroflexi	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3889797_1	479434.Sthe_1924	9.744e-99	327.0	COG2141@1|root,COG2141@2|Bacteria,2G869@200795|Chloroflexi,27XFF@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_3896133_1	479434.Sthe_1347	2.637e-93	309.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_3896133_2	479434.Sthe_1346	4.968e-69	238.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi,27YC8@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
MMS3_k127_3896133_0	479434.Sthe_1345	2.624e-100	339.0	COG3693@1|root,COG3693@2|Bacteria,2GBGU@200795|Chloroflexi,27XYU@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
MMS3_k127_3897619_1	1116472.MGMO_35c00160	4.898e-45	166.0	COG3795@1|root,COG3795@2|Bacteria,1RK95@1224|Proteobacteria,1S6H7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
MMS3_k127_3897619_3	479434.Sthe_2959	7.915e-37	141.0	COG1977@1|root,COG1977@2|Bacteria,2G6VH@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3897619_0	926550.CLDAP_33430	1.591e-207	649.0	COG4447@1|root,COG4447@2|Bacteria,2G5ZD@200795|Chloroflexi	200795|Chloroflexi	S	BNR/Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR
MMS3_k127_3897619_2	479434.Sthe_2956	5.133e-42	157.0	COG0346@1|root,COG0346@2|Bacteria,2G7HN@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_3897619_4	436229.JOEH01000008_gene4208	4.535e-21	93.0	COG4430@1|root,COG4430@2|Bacteria,2I1Y7@201174|Actinobacteria,2NK6V@228398|Streptacidiphilus	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3901661_16	194867.ALBQ01000011_gene132	2.465e-30	139.0	COG3210@1|root,COG3291@1|root,COG3468@1|root,COG4625@1|root,COG4932@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3468@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria,2TX5F@28211|Alphaproteobacteria,2KEGN@204457|Sphingomonadales	204457|Sphingomonadales	MU	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,He_PIG,TIG
MMS3_k127_3901661_9	1284352.AOIG01000013_gene3550	5.791e-61	235.0	COG0457@1|root,COG3210@1|root,COG5492@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Invasin_D3,SLH
MMS3_k127_3901661_0	479434.Sthe_2141	3.733e-217	709.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	200795|Chloroflexi	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
MMS3_k127_3901661_5	867845.KI911784_gene1957	4.895e-81	278.0	COG1028@1|root,COG1028@2|Bacteria,2G8DK@200795|Chloroflexi,3776U@32061|Chloroflexia	32061|Chloroflexia	IQ	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
MMS3_k127_3901661_4	1304876.AZVC01000002_gene629	1.507e-92	319.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,1WC7U@1268|Micrococcaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	3.5.1.46	ko:K01453	ko00930,ko01120,map00930,map01120	-	R00059,R10975,R10979	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	Beta-lactamase
MMS3_k127_3901661_18	1380347.JNII01000008_gene4314	1.83e-14	78.0	2C6EM@1|root,2ZFYQ@2|Bacteria,2GXX8@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
MMS3_k127_3901661_20	1122919.KB905558_gene1272	1.38e-10	69.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	DinB_2,Metallophos_2
MMS3_k127_3901661_11	1132509.C447_03481	1.547e-52	192.0	COG1335@1|root,arCOG01943@2157|Archaea,2XWJY@28890|Euryarchaeota,23V5P@183963|Halobacteria	183963|Halobacteria	Q	COG1335 Amidases related to nicotinamidase	entB1	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
MMS3_k127_3901661_13	1476876.JOJO01000069_gene3058	5.081e-47	181.0	COG3173@1|root,COG3173@2|Bacteria,2H16C@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.163	ko:K18817	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
MMS3_k127_3901661_2	1068978.AMETH_5983	1.94e-111	381.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,4DYA6@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_3901661_12	1306990.BARG01000069_gene7671	1.757e-49	184.0	COG1309@1|root,COG1309@2|Bacteria,2GJXV@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
MMS3_k127_3901661_3	1463854.JOHT01000015_gene5277	5.967e-98	327.0	COG4976@1|root,COG4976@2|Bacteria,2ICH4@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_3901661_8	1121920.AUAU01000004_gene742	1.172e-61	215.0	COG3832@1|root,COG3832@2|Bacteria,3Y57B@57723|Acidobacteria	57723|Acidobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMS3_k127_3901661_15	999541.bgla_2g17140	1.144e-32	130.0	COG0640@1|root,COG0640@2|Bacteria,1N0DJ@1224|Proteobacteria,2VUPS@28216|Betaproteobacteria,1K8ZU@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_3901661_6	1487953.JMKF01000027_gene1488	2.788e-79	268.0	COG3576@1|root,COG3576@2|Bacteria,1G5D9@1117|Cyanobacteria,1HAHC@1150|Oscillatoriales	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
MMS3_k127_3901661_7	926560.KE387025_gene4078	2.493e-77	278.0	29MNG@1|root,308K7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3901661_1	1121877.JQKF01000003_gene1555	2.555e-143	468.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CN9T@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome b/b6/petB	-	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
MMS3_k127_3901661_10	529884.Rhola_00008350	3.021e-58	213.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,4FKHS@85023|Microbacteriaceae	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	qcrA	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
MMS3_k127_3901661_17	525909.Afer_1827	1.079e-16	83.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,4CNJZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
MMS3_k127_3906729_4	479434.Sthe_0613	4.959e-103	345.0	COG2897@1|root,COG2897@2|Bacteria,2GAAF@200795|Chloroflexi,27Y5E@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS3_k127_3906729_0	309801.trd_1745	5.031e-189	602.0	COG5476@1|root,COG5476@2|Bacteria,2G7N8@200795|Chloroflexi,27YXI@189775|Thermomicrobia	189775|Thermomicrobia	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
MMS3_k127_3906729_3	309801.trd_1744	1.918e-128	415.0	COG3246@1|root,COG3246@2|Bacteria,2G81V@200795|Chloroflexi,27YYT@189775|Thermomicrobia	189775|Thermomicrobia	S	beta-keto acid cleavage enzyme	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
MMS3_k127_3906729_7	1210908.HSB1_28770	6.871e-53	197.0	COG0596@1|root,arCOG01648@2157|Archaea,2XV6R@28890|Euryarchaeota	28890|Euryarchaeota	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_3906729_6	479434.Sthe_0689	1.503e-72	252.0	28NSZ@1|root,2ZBRT@2|Bacteria,2G732@200795|Chloroflexi,27Y9F@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3906729_1	479434.Sthe_0688	3.737e-162	520.0	COG0205@1|root,COG0205@2|Bacteria,2G81H@200795|Chloroflexi,27Y44@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
MMS3_k127_3906729_11	309801.trd_1097	3.39e-36	140.0	COG1359@1|root,COG1359@2|Bacteria,2GA18@200795|Chloroflexi,27YJ7@189775|Thermomicrobia	189775|Thermomicrobia	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
MMS3_k127_3906729_8	479434.Sthe_0685	3.402e-45	168.0	COG1310@1|root,COG1310@2|Bacteria,2G7CC@200795|Chloroflexi,27YR1@189775|Thermomicrobia	189775|Thermomicrobia	S	JAB/MPN domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
MMS3_k127_3906729_5	479434.Sthe_0684	2.06e-78	269.0	COG1794@1|root,COG1794@2|Bacteria,2G9I5@200795|Chloroflexi,27Y7T@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
MMS3_k127_3906729_10	479434.Sthe_0683	3.435e-43	163.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_3906729_9	479434.Sthe_0682	5.365e-44	161.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi	200795|Chloroflexi	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
MMS3_k127_3906729_2	479434.Sthe_0677	2.689e-150	478.0	COG0161@1|root,COG0161@2|Bacteria,2G7Y3@200795|Chloroflexi,27XVZ@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
MMS3_k127_3915815_1	479434.Sthe_1313	3.103e-76	261.0	2C5T0@1|root,337HV@2|Bacteria,2G9CN@200795|Chloroflexi,27Y76@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3915815_0	479434.Sthe_1315	8.224e-164	524.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi,27Z1G@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_3920127_1	221288.JH992901_gene4311	3.879e-15	78.0	COG2227@1|root,COG2227@2|Bacteria,1GQZP@1117|Cyanobacteria,1JKUR@1189|Stigonemataceae	1117|Cyanobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
MMS3_k127_3920127_0	1356854.N007_11055	5.817e-33	131.0	COG1695@1|root,COG1695@2|Bacteria,1VC2Z@1239|Firmicutes,4HINE@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
MMS3_k127_3920127_2	1356854.N007_11050	2.41e-09	59.0	2EUC9@1|root,33MUN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3927429_1	479434.Sthe_3484	5.568e-83	283.0	COG0630@1|root,COG0630@2|Bacteria,2G943@200795|Chloroflexi,27YBM@189775|Thermomicrobia	189775|Thermomicrobia	NU	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3927429_0	266117.Rxyl_2946	9.805e-120	422.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
MMS3_k127_3927429_3	251221.35211658	2.965e-53	215.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,Trans_reg_C
MMS3_k127_3927429_2	1122138.AQUZ01000041_gene7289	1.523e-76	261.0	COG3896@1|root,COG3896@2|Bacteria,2IFF0@201174|Actinobacteria	201174|Actinobacteria	V	chloramphenicol	cpt	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
MMS3_k127_3927429_5	868131.MSWAN_0985	1.014e-23	103.0	COG2329@1|root,arCOG05403@2157|Archaea,2Y22C@28890|Euryarchaeota	28890|Euryarchaeota	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
MMS3_k127_3927429_4	981369.JQMJ01000004_gene4133	1.018e-34	137.0	COG2230@1|root,COG2230@2|Bacteria,2I449@201174|Actinobacteria,2NGQ4@228398|Streptacidiphilus	201174|Actinobacteria	M	Dimerisation domain	-	-	-	ko:K21192	ko01059,ko01130,map01059,map01130	M00829	R11371	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimerisation2,Methyltransf_2
MMS3_k127_3946308_11	479434.Sthe_1294	8.702e-120	390.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi,27Y2T@189775|Thermomicrobia	2|Bacteria	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
MMS3_k127_3946308_4	479434.Sthe_1293	4.85e-224	700.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi,27XJC@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
MMS3_k127_3946308_10	479434.Sthe_1292	8.847e-139	446.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia	189775|Thermomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
MMS3_k127_3946308_16	309801.trd_0747	3.712e-28	117.0	COG1828@1|root,COG1828@2|Bacteria,2GBWK@200795|Chloroflexi,27YN2@189775|Thermomicrobia	189775|Thermomicrobia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
MMS3_k127_3946308_12	479434.Sthe_1290	2.893e-117	381.0	COG0047@1|root,COG0047@2|Bacteria,2G6R9@200795|Chloroflexi,27XM6@189775|Thermomicrobia	189775|Thermomicrobia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
MMS3_k127_3946308_0	479434.Sthe_1289	0.0	1044.0	COG0046@1|root,COG0046@2|Bacteria,2G5Z1@200795|Chloroflexi,27XNA@189775|Thermomicrobia	189775|Thermomicrobia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
MMS3_k127_3946308_3	479434.Sthe_1288	2.982e-237	743.0	COG0034@1|root,COG0034@2|Bacteria,2G61T@200795|Chloroflexi,27XUW@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
MMS3_k127_3946308_8	479434.Sthe_1287	1.51e-170	542.0	COG0404@1|root,COG0404@2|Bacteria,2G5VA@200795|Chloroflexi,27XV3@189775|Thermomicrobia	189775|Thermomicrobia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
MMS3_k127_3946308_13	479434.Sthe_1286	3.539e-54	194.0	COG0509@1|root,COG0509@2|Bacteria,2G6XE@200795|Chloroflexi,27YEK@189775|Thermomicrobia	189775|Thermomicrobia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
MMS3_k127_3946308_7	309801.trd_0754	1.632e-173	554.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi,27XGH@189775|Thermomicrobia	189775|Thermomicrobia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	-	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
MMS3_k127_3946308_6	479434.Sthe_1283	3.285e-193	610.0	COG0112@1|root,COG0112@2|Bacteria,2G624@200795|Chloroflexi,27XXZ@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
MMS3_k127_3946308_9	479434.Sthe_1282	5.407e-154	496.0	COG0472@1|root,COG0472@2|Bacteria,2G6H5@200795|Chloroflexi,27Y1S@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
MMS3_k127_3946308_14	479434.Sthe_1281	3.877e-45	168.0	COG2331@1|root,COG2331@2|Bacteria,2G795@200795|Chloroflexi,27YPR@189775|Thermomicrobia	189775|Thermomicrobia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMS3_k127_3946308_15	1382356.JQMP01000003_gene2097	1.99e-32	130.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi,27Z7R@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal silencing factor during starvation	-	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
MMS3_k127_3946308_1	760568.Desku_2854	5.931e-262	840.0	COG3280@1|root,COG3280@2|Bacteria,1USD2@1239|Firmicutes,25ACB@186801|Clostridia,264MA@186807|Peptococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
MMS3_k127_3946308_5	264732.Moth_1809	8.515e-209	668.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,42FTG@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459
MMS3_k127_3946308_2	1382356.JQMP01000004_gene488	2.663e-237	739.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
MMS3_k127_3965585_0	1214101.BN159_1215	4.396e-236	741.0	COG0457@1|root,COG0457@2|Bacteria,2HX8A@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
MMS3_k127_3965585_2	485913.Krac_2397	1.696e-68	247.0	COG0842@1|root,COG0842@2|Bacteria,2G774@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMS3_k127_3965585_1	485913.Krac_3488	1.715e-88	299.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_3965585_3	1385511.N783_00755	6.15e-40	161.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes	1239|Firmicutes	P	sulfurtransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
MMS3_k127_3968089_5	1336243.JAEA01000011_gene3180	2.273e-43	165.0	COG1309@1|root,COG1309@2|Bacteria,1RKMF@1224|Proteobacteria,2UAP3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	WHG
MMS3_k127_3968089_3	312284.A20C1_11541	1.314e-73	257.0	COG2267@1|root,COG2267@2|Bacteria,2GQC1@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
MMS3_k127_3968089_6	1303518.CCALI_01298	9.62e-43	162.0	COG2323@1|root,COG2323@2|Bacteria	2|Bacteria	K	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
MMS3_k127_3968089_0	479434.Sthe_2548	4.48e-129	426.0	2DQ2F@1|root,334G7@2|Bacteria,2G92Q@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3968089_7	997346.HMPREF9374_0887	2.029e-21	102.0	COG0586@1|root,COG0586@2|Bacteria,1V545@1239|Firmicutes,4I3NG@91061|Bacilli,27D08@186824|Thermoactinomycetaceae	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_3968089_2	264732.Moth_1477	6.054e-83	292.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,42HW1@68295|Thermoanaerobacterales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_3968089_4	33876.JNXY01000003_gene26	3.78e-72	251.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4DCU0@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_3968089_1	1382306.JNIM01000001_gene3124	2.999e-94	316.0	COG4705@1|root,COG4705@2|Bacteria	2|Bacteria	T	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
MMS3_k127_3968089_8	662479.C440_14989	9.894e-05	49.0	COG0589@1|root,arCOG02053@2157|Archaea,2Y28M@28890|Euryarchaeota	28890|Euryarchaeota	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_3975110_3	479434.Sthe_1686	5.87e-09	60.0	COG1286@1|root,COG2340@1|root,COG1286@2|Bacteria,COG2340@2|Bacteria,2G7IY@200795|Chloroflexi	200795|Chloroflexi	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
MMS3_k127_3975110_1	479434.Sthe_1500	2.589e-102	348.0	COG0520@1|root,COG0520@2|Bacteria,2G7JU@200795|Chloroflexi,27XQN@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
MMS3_k127_3975110_0	1121430.JMLG01000002_gene1082	2.753e-126	415.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,262E3@186807|Peptococcaceae	186801|Clostridia	C	PFAM CoA-transferase family III	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
MMS3_k127_3975110_2	479434.Sthe_0725	7.919e-13	71.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_398050_8	479434.Sthe_1975	2.757e-147	476.0	COG2730@1|root,COG2730@2|Bacteria,2GBH8@200795|Chloroflexi,27Y4J@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
MMS3_k127_398050_10	309801.trd_1489	5.407e-108	362.0	COG0477@1|root,COG2814@2|Bacteria,2GBPV@200795|Chloroflexi,27Z1P@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
MMS3_k127_398050_13	13689.BV96_02976	1.649e-65	235.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,2K1BU@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM amidohydrolase 2	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
MMS3_k127_398050_1	479434.Sthe_1407	1.61e-251	788.0	COG1529@1|root,COG1529@2|Bacteria,2GB0H@200795|Chloroflexi,27XUI@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_398050_14	867845.KI911784_gene3220	5.488e-62	216.0	COG1529@1|root,COG1529@2|Bacteria,2G608@200795|Chloroflexi,376SU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_398050_15	1121428.DESHY_40048___1	2.705e-54	200.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,260VS@186807|Peptococcaceae	186801|Clostridia	IQ	PFAM short chain dehydrogenase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_398050_9	479434.Sthe_0124	4.716e-138	453.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi,27YS9@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_398050_11	479434.Sthe_0123	5.638e-107	353.0	COG4242@1|root,COG4242@2|Bacteria,2G6C3@200795|Chloroflexi,27XM7@189775|Thermomicrobia	189775|Thermomicrobia	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_398050_18	479434.Sthe_0113	4.215e-25	110.0	COG1545@1|root,COG1545@2|Bacteria,2GBG0@200795|Chloroflexi,27ZCR@189775|Thermomicrobia	189775|Thermomicrobia	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	OB_aCoA_assoc
MMS3_k127_398050_2	479434.Sthe_0112	1.065e-191	603.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi,27YZ2@189775|Thermomicrobia	189775|Thermomicrobia	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_398050_6	309801.trd_A0396	9.187e-156	498.0	COG1834@1|root,COG1834@2|Bacteria,2G9XN@200795|Chloroflexi,27YVU@189775|Thermomicrobia	189775|Thermomicrobia	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
MMS3_k127_398050_5	479434.Sthe_3080	1.133e-160	514.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,27YZ1@189775|Thermomicrobia	189775|Thermomicrobia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
MMS3_k127_398050_17	1382356.JQMP01000003_gene1750	3.869e-25	112.0	29N8W@1|root,3096R@2|Bacteria,2GA5T@200795|Chloroflexi,27ZC3@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_398050_7	479434.Sthe_3081	3.239e-153	522.0	COG0643@1|root,COG0784@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,2G6G3@200795|Chloroflexi,27YJZ@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K02487,ko:K03407,ko:K06596	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
MMS3_k127_398050_4	479434.Sthe_0104	1.547e-162	517.0	COG4447@1|root,COG4447@2|Bacteria,2G8DW@200795|Chloroflexi,27YX3@189775|Thermomicrobia	189775|Thermomicrobia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_398050_3	479434.Sthe_0170	2.053e-186	590.0	COG0665@1|root,COG0665@2|Bacteria,2G8SD@200795|Chloroflexi,27Z3M@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_398050_16	479434.Sthe_0171	4.47e-41	157.0	COG0484@1|root,COG0484@2|Bacteria,2GBGQ@200795|Chloroflexi,27YJ1@189775|Thermomicrobia	189775|Thermomicrobia	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K17867	-	-	-	-	ko00000,ko03012	-	-	-	DnaJ
MMS3_k127_398050_19	309801.trd_0653	3.085e-14	86.0	COG1560@1|root,COG1560@2|Bacteria,2G7BA@200795|Chloroflexi,27Y7M@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMS3_k127_398050_20	383372.Rcas_3141	4.301e-11	76.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi,37789@32061|Chloroflexia	32061|Chloroflexia	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
MMS3_k127_398050_12	479434.Sthe_0128	6.418e-72	253.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_398050_0	479434.Sthe_0258	0.0	1047.0	COG1529@1|root,COG1529@2|Bacteria,2G82V@200795|Chloroflexi,27XQT@189775|Thermomicrobia	189775|Thermomicrobia	C	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_3985494_11	479434.Sthe_0320	1.113e-62	222.0	2AJAY@1|root,319W4@2|Bacteria,2GAAA@200795|Chloroflexi,27YHU@189775|Thermomicrobia	189775|Thermomicrobia	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
MMS3_k127_3985494_13	479434.Sthe_0319	4.247e-32	128.0	2BQKT@1|root,32JGU@2|Bacteria,2GBB5@200795|Chloroflexi,27YMH@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_3985494_0	479434.Sthe_0318	4.224e-285	884.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi,27XK2@189775|Thermomicrobia	189775|Thermomicrobia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B_2,RMMBL
MMS3_k127_3985494_7	479434.Sthe_0316	4.111e-110	360.0	COG2872@1|root,COG2872@2|Bacteria,2GA6P@200795|Chloroflexi,27XNC@189775|Thermomicrobia	189775|Thermomicrobia	S	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
MMS3_k127_3985494_6	479434.Sthe_0315	2.962e-143	465.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi,27Y2R@189775|Thermomicrobia	189775|Thermomicrobia	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
MMS3_k127_3985494_4	479434.Sthe_0301	2.224e-233	730.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi,27XVQ@189775|Thermomicrobia	189775|Thermomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMS3_k127_3985494_2	479434.Sthe_0300	8.827e-247	771.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi,27XEU@189775|Thermomicrobia	189775|Thermomicrobia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
MMS3_k127_3985494_1	479434.Sthe_0299	1.899e-283	883.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi,27XR2@189775|Thermomicrobia	189775|Thermomicrobia	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
MMS3_k127_3985494_12	479434.Sthe_0298	4.608e-43	159.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi,27YDH@189775|Thermomicrobia	189775|Thermomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMS3_k127_3985494_9	479434.Sthe_0297	2.234e-96	321.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi,27Y64@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
MMS3_k127_3985494_5	309801.trd_1784	8.373e-170	538.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi,27XUJ@189775|Thermomicrobia	189775|Thermomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
MMS3_k127_3985494_3	479434.Sthe_0295	1.698e-238	741.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi,27XG6@189775|Thermomicrobia	189775|Thermomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
MMS3_k127_3985494_10	479434.Sthe_0294	5.566e-96	319.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi,27XQI@189775|Thermomicrobia	189775|Thermomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
MMS3_k127_3985494_8	479434.Sthe_0293	1.529e-106	348.0	COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi,27XWB@189775|Thermomicrobia	189775|Thermomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMS3_k127_3985494_14	479434.Sthe_0291	3.013e-16	85.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,27XN3@189775|Thermomicrobia	189775|Thermomicrobia	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
MMS3_k127_4001233_2	864069.MicloDRAFT_00033110	3.744e-05	48.0	2DNSF@1|root,32YX1@2|Bacteria,1R3H3@1224|Proteobacteria,2UI8N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4001233_0	479434.Sthe_2591	1.955e-88	305.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_4001233_1	882082.SaccyDRAFT_3033	1.131e-54	196.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4E0K0@85010|Pseudonocardiales	201174|Actinobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_4009193_0	479434.Sthe_0805	6.685e-264	822.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,27Y57@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
MMS3_k127_4009193_1	479434.Sthe_0804	1.554e-06	52.0	COG3807@1|root,COG3807@2|Bacteria,2GBAP@200795|Chloroflexi,27YJC@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
MMS3_k127_4010401_2	479434.Sthe_1838	1.804e-234	730.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi,27XFC@189775|Thermomicrobia	189775|Thermomicrobia	H	Nucleotidyl transferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
MMS3_k127_4010401_6	479434.Sthe_1837	7.048e-167	531.0	COG1085@1|root,COG1085@2|Bacteria,2G848@200795|Chloroflexi,27XWY@189775|Thermomicrobia	189775|Thermomicrobia	C	galactose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4010401_0	479434.Sthe_2889	6.016e-271	850.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	2|Bacteria	EQ	Hydantoinaseoxoprolinase domain protein	oplaH	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
MMS3_k127_4010401_3	479434.Sthe_2890	1.99e-208	662.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi,27XUU@189775|Thermomicrobia	2|Bacteria	EQ	PFAM Hydantoinase B oxoprolinase	MA20_04180	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01474	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
MMS3_k127_4010401_1	479434.Sthe_1462	1.201e-238	754.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi,27Y2G@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_4010401_7	479434.Sthe_1461	2.68e-147	471.0	COG0601@1|root,COG0601@2|Bacteria,2G5Z7@200795|Chloroflexi,27XQJ@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_4010401_8	309801.trd_1253	8.074e-131	424.0	COG1173@1|root,COG1173@2|Bacteria,2G63I@200795|Chloroflexi,27XQD@189775|Thermomicrobia	189775|Thermomicrobia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_4010401_4	479434.Sthe_1459	1.527e-188	597.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi,27XPE@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_4010401_10	479434.Sthe_1458	5.174e-88	301.0	COG0083@1|root,COG0083@2|Bacteria,2G6MP@200795|Chloroflexi,27Y5U@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
MMS3_k127_4010401_5	479434.Sthe_1457	7.724e-174	565.0	COG0747@1|root,COG0747@2|Bacteria,2G6MN@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_4010401_13	479434.Sthe_1451	2.55e-32	132.0	COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi,27YM8@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
MMS3_k127_4010401_11	479434.Sthe_1450	5.397e-46	170.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi,27YIZ@189775|Thermomicrobia	189775|Thermomicrobia	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
MMS3_k127_4010401_12	479434.Sthe_1449	1.506e-36	141.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi,27YKT@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
MMS3_k127_4010401_9	479434.Sthe_1448	8.62e-108	365.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi,27XG1@189775|Thermomicrobia	189775|Thermomicrobia	O	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_3
MMS3_k127_4019950_4	1382356.JQMP01000004_gene610	6.031e-12	66.0	COG2761@1|root,COG2761@2|Bacteria,2G9IQ@200795|Chloroflexi	200795|Chloroflexi	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
MMS3_k127_4019950_3	479434.Sthe_0726	9.535e-74	253.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi,27Y6K@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
MMS3_k127_4019950_0	479434.Sthe_0727	2.591e-260	816.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
MMS3_k127_4019950_1	1380347.JNII01000006_gene1824	1.512e-137	463.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EX5G@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
MMS3_k127_4019950_2	1146883.BLASA_1056	7.172e-76	260.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_4021845_3	392499.Swit_2767	1.08e-44	163.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,2K0BK@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
MMS3_k127_4021845_0	1380355.JNIJ01000058_gene178	0.0	1482.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2TS9I@28211|Alphaproteobacteria,3K0U1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
MMS3_k127_4021845_2	391625.PPSIR1_38324	4.856e-83	289.0	COG0732@1|root,COG0732@2|Bacteria,1R5R8@1224|Proteobacteria,42Q25@68525|delta/epsilon subdivisions,2WMEQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
MMS3_k127_4021845_1	1380355.JNIJ01000058_gene177	1.532e-221	693.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,2TQQA@28211|Alphaproteobacteria,3JZM1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	HsdM N-terminal domain	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
MMS3_k127_4023990_0	215803.DB30_4638	2.156e-177	577.0	COG0515@1|root,COG0515@2|Bacteria,1R7I2@1224|Proteobacteria,4397P@68525|delta/epsilon subdivisions,2X4EK@28221|Deltaproteobacteria,2YYVD@29|Myxococcales	28221|Deltaproteobacteria	KLT	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like,Pkinase
MMS3_k127_4023990_1	930171.Asphe3_21340	4.6e-42	163.0	2E9HK@1|root,333QQ@2|Bacteria,2GPQ1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_402832_6	1410609.JHVB01000007_gene1042	2.744e-09	61.0	COG1680@1|root,COG1680@2|Bacteria,2J8WD@203691|Spirochaetes	203691|Spirochaetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
MMS3_k127_402832_4	391623.TERMP_01739	1.06e-18	92.0	COG0463@1|root,arCOG00894@2157|Archaea,2XWXA@28890|Euryarchaeota,242RY@183968|Thermococci	183968|Thermococci	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
MMS3_k127_402832_2	309801.trd_1496	2.951e-44	166.0	COG1285@1|root,COG1285@2|Bacteria,2G77U@200795|Chloroflexi,27YGD@189775|Thermomicrobia	189775|Thermomicrobia	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
MMS3_k127_402832_1	309801.trd_0014	4.077e-82	277.0	COG0566@1|root,COG0566@2|Bacteria,2GA03@200795|Chloroflexi,27Y5B@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
MMS3_k127_402832_0	479434.Sthe_2425	9.397e-126	415.0	COG1565@1|root,COG1565@2|Bacteria,2G8NS@200795|Chloroflexi,27Y3B@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
MMS3_k127_402832_3	479434.Sthe_2426	6.971e-41	156.0	COG1225@1|root,COG1225@2|Bacteria,2GA29@200795|Chloroflexi,27YRA@189775|Thermomicrobia	189775|Thermomicrobia	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMS3_k127_402832_5	479434.Sthe_2402	3.374e-16	89.0	COG2834@1|root,COG2834@2|Bacteria,2GBFM@200795|Chloroflexi,27ZBH@189775|Thermomicrobia	189775|Thermomicrobia	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4035247_7	1203568.HMPREF1484_01818	0.0007647	44.0	28M80@1|root,2ZAM9@2|Bacteria,2H22E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4035247_6	240016.ABIZ01000001_gene2117	2.472e-31	135.0	COG0657@1|root,COG0657@2|Bacteria,46VAH@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
MMS3_k127_4035247_5	326424.FRAAL2583	4.867e-45	170.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
MMS3_k127_4035247_8	926560.KE387023_gene2056	0.0009954	50.0	COG1668@1|root,COG1668@2|Bacteria,1WM79@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
MMS3_k127_4035247_4	765420.OSCT_0605	2.808e-77	269.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi,374U5@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_4035247_3	1382356.JQMP01000003_gene1829	2.435e-100	349.0	COG1840@1|root,COG1840@2|Bacteria,2GBNE@200795|Chloroflexi,27ZCW@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4035247_1	1123320.KB889563_gene6419	2.089e-119	402.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
MMS3_k127_4035247_0	521045.Kole_0200	2.726e-183	581.0	COG0004@1|root,COG0004@2|Bacteria,2GD3C@200918|Thermotogae	200918|Thermotogae	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMS3_k127_4035247_2	28444.JODQ01000006_gene152	2.144e-107	372.0	COG0369@1|root,COG1716@1|root,COG5274@1|root,COG0369@2|Bacteria,COG1716@2|Bacteria,COG5274@2|Bacteria,2I3UN@201174|Actinobacteria	201174|Actinobacteria	P	ATPase activity	-	-	1.14.14.1,1.6.2.4	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko00199,ko01000	-	-	-	NAD_binding_1
MMS3_k127_4041251_3	1123401.JHYQ01000021_gene1015	7.105e-05	46.0	COG0864@1|root,COG0864@2|Bacteria,1N84E@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
MMS3_k127_4041251_2	1123401.JHYQ01000021_gene1016	1.494e-29	122.0	COG2337@1|root,COG2337@2|Bacteria,1N1DE@1224|Proteobacteria	1224|Proteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
MMS3_k127_4041251_0	1041147.AUFB01000006_gene2130	4.507e-104	345.0	COG1595@1|root,COG1595@2|Bacteria,1R44W@1224|Proteobacteria,2U1R0@28211|Alphaproteobacteria,4BBNK@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
MMS3_k127_4041251_1	1040986.ATYO01000003_gene5897	4.219e-32	127.0	COG3224@1|root,COG3224@2|Bacteria,1N2DP@1224|Proteobacteria,2UBSR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
MMS3_k127_4049966_6	479434.Sthe_0614	2.65e-21	97.0	COG0221@1|root,COG0221@2|Bacteria,2GA0X@200795|Chloroflexi,27YH7@189775|Thermomicrobia	189775|Thermomicrobia	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
MMS3_k127_4049966_4	479434.Sthe_0615	2.363e-36	139.0	COG4031@1|root,COG4031@2|Bacteria	2|Bacteria	S	Predicted metal-binding protein (DUF2103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2103
MMS3_k127_4049966_1	1382306.JNIM01000001_gene3776	1.303e-235	744.0	COG1132@1|root,COG1132@2|Bacteria,2G7QD@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_4049966_0	479434.Sthe_0253	2.451e-313	997.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi,27XS8@189775|Thermomicrobia	189775|Thermomicrobia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
MMS3_k127_4049966_2	479434.Sthe_3140	2.651e-146	488.0	COG3568@1|root,COG3568@2|Bacteria,2G7ER@200795|Chloroflexi,27XU2@189775|Thermomicrobia	189775|Thermomicrobia	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
MMS3_k127_4049966_3	479434.Sthe_0395	5.994e-44	169.0	2CKD9@1|root,333BQ@2|Bacteria,2G7BT@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4049966_7	1121472.AQWN01000001_gene77	3.038e-14	74.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,248A6@186801|Clostridia,2610J@186807|Peptococcaceae	186801|Clostridia	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
MMS3_k127_4053467_2	479434.Sthe_1003	2.97e-60	209.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi,27Y0Z@189775|Thermomicrobia	189775|Thermomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
MMS3_k127_4053467_1	479434.Sthe_1002	1.318e-154	494.0	COG1494@1|root,COG1494@2|Bacteria,2G5XR@200795|Chloroflexi,27XXS@189775|Thermomicrobia	189775|Thermomicrobia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
MMS3_k127_4053467_0	479434.Sthe_1001	1.221e-181	577.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi,27XGW@189775|Thermomicrobia	189775|Thermomicrobia	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2,RNase_T
MMS3_k127_4054540_3	263358.VAB18032_20540	2.657e-52	212.0	COG0577@1|root,COG0577@2|Bacteria,2GNEX@201174|Actinobacteria,4DCK8@85008|Micromonosporales	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
MMS3_k127_4054540_1	28444.JODQ01000001_gene2596	4.932e-134	468.0	COG0577@1|root,COG0577@2|Bacteria,2H997@201174|Actinobacteria,4EGB7@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
MMS3_k127_4054540_2	479434.Sthe_0693	3.07e-119	391.0	COG1131@1|root,COG1131@2|Bacteria,2G5YX@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_4054540_0	479434.Sthe_0692	3.158e-134	432.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMS3_k127_4054540_4	479434.Sthe_0690	1.294e-44	167.0	COG1670@1|root,COG1670@2|Bacteria,2G73Y@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_4056150_4	479434.Sthe_0619	6.766e-48	173.0	COG2897@1|root,COG2897@2|Bacteria,2G8NA@200795|Chloroflexi,27Y2I@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS3_k127_4056150_3	479434.Sthe_1234	2.749e-109	373.0	COG5476@1|root,COG5476@2|Bacteria,2G7N8@200795|Chloroflexi,27YXI@189775|Thermomicrobia	189775|Thermomicrobia	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
MMS3_k127_4056150_1	1054213.HMPREF9946_03839	1.779e-114	384.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2U8HJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
MMS3_k127_4056150_0	479434.Sthe_1624	1.472e-116	382.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi,27Y61@189775|Thermomicrobia	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_4056150_2	479434.Sthe_1623	1.743e-111	368.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_4059277_1	66373.JOFQ01000002_gene5207	1.763e-41	159.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
MMS3_k127_4059277_0	485913.Krac_5345	4.309e-59	211.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
MMS3_k127_4060093_6	1382356.JQMP01000004_gene610	7.679e-40	151.0	COG2761@1|root,COG2761@2|Bacteria,2G9IQ@200795|Chloroflexi	200795|Chloroflexi	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
MMS3_k127_4060093_2	479434.Sthe_0724	1.067e-143	465.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
MMS3_k127_4060093_1	479434.Sthe_0720	4.15e-172	546.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,27XS7@189775|Thermomicrobia	189775|Thermomicrobia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMS3_k127_4060093_4	479434.Sthe_0719	6.904e-102	347.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,27XPY@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
MMS3_k127_4060093_3	479434.Sthe_0716	6.858e-118	389.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,27Y42@189775|Thermomicrobia	189775|Thermomicrobia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
MMS3_k127_4060093_5	479434.Sthe_0715	4.861e-58	212.0	COG0576@1|root,COG0576@2|Bacteria,2G6WR@200795|Chloroflexi,27YDX@189775|Thermomicrobia	189775|Thermomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
MMS3_k127_4060093_0	479434.Sthe_0714	0.0	1039.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi,27Y4Z@189775|Thermomicrobia	189775|Thermomicrobia	O	MreB/Mbl protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
MMS3_k127_4082562_2	479434.Sthe_1749	2.12e-128	419.0	COG2870@1|root,COG2870@2|Bacteria,2G6G0@200795|Chloroflexi,27Y48@189775|Thermomicrobia	189775|Thermomicrobia	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
MMS3_k127_4082562_1	479434.Sthe_2613	9.198e-134	432.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi,27Y2F@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
MMS3_k127_4082562_6	479434.Sthe_2612	1.9e-52	194.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi,27YIQ@189775|Thermomicrobia	189775|Thermomicrobia	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
MMS3_k127_4082562_5	479434.Sthe_1751	2.529e-70	243.0	COG0615@1|root,COG0615@2|Bacteria,2G6NJ@200795|Chloroflexi,27Y9C@189775|Thermomicrobia	189775|Thermomicrobia	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
MMS3_k127_4082562_0	479434.Sthe_1752	6.28e-213	675.0	COG0728@1|root,COG0728@2|Bacteria,2G5PF@200795|Chloroflexi,27Y0W@189775|Thermomicrobia	189775|Thermomicrobia	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMS3_k127_4082562_7	479434.Sthe_1753	7.722e-48	177.0	COG5615@1|root,COG5615@2|Bacteria,2GBBE@200795|Chloroflexi,27YNG@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	CopD
MMS3_k127_4082562_3	479434.Sthe_1848	1.866e-112	378.0	COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi,27YYU@189775|Thermomicrobia	189775|Thermomicrobia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
MMS3_k127_4082562_4	479434.Sthe_1757	8.79e-83	278.0	COG1388@1|root,COG4990@1|root,COG1388@2|Bacteria,COG4990@2|Bacteria,2G95J@200795|Chloroflexi,27Y1K@189775|Thermomicrobia	189775|Thermomicrobia	M	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_C39_2
MMS3_k127_4091295_0	479434.Sthe_2141	3.838e-197	642.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	200795|Chloroflexi	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
MMS3_k127_4091295_2	608538.HTH_1380	4.04e-37	163.0	COG3210@1|root,COG3227@1|root,COG3210@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	3.2.1.18,3.4.11.10	ko:K01186,ko:K05994,ko:K21449	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko01002,ko02000,ko02042	1.B.40.2	GH33	-	Beta_helix,PKD,Peptidase_S74,fn3
MMS3_k127_4091295_1	316067.Geob_1283	2.286e-76	291.0	COG1361@1|root,COG1404@1|root,COG3210@1|root,COG4625@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin_3,DUF11,DUF4347,He_PIG,PATR
MMS3_k127_4097396_0	479434.Sthe_3019	1.121e-146	468.0	COG0447@1|root,COG0447@2|Bacteria,2G66W@200795|Chloroflexi,27Y0G@189775|Thermomicrobia	189775|Thermomicrobia	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_4097396_1	479434.Sthe_3018	2.595e-113	372.0	COG1575@1|root,COG1575@2|Bacteria,2G5ZC@200795|Chloroflexi,27XVA@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
MMS3_k127_4097396_2	479434.Sthe_3017	1.766e-95	325.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,27YF9@189775|Thermomicrobia	189775|Thermomicrobia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
MMS3_k127_4097396_3	485913.Krac_2227	5.388e-36	138.0	COG0454@1|root,COG1846@1|root,COG0454@2|Bacteria,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ybfA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,MarR_2
MMS3_k127_410376_0	937777.Deipe_0671	6.367e-95	320.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
MMS3_k127_410376_2	1196323.ALKF01000195_gene1957	1.318e-74	261.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,26S4B@186822|Paenibacillaceae	91061|Bacilli	L	8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_410376_4	1121440.AUMA01000010_gene327	1.099e-29	125.0	COG1437@1|root,COG1437@2|Bacteria,1RJYE@1224|Proteobacteria,42ZWS@68525|delta/epsilon subdivisions,2WVBV@28221|Deltaproteobacteria,2MBNM@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
MMS3_k127_410376_3	479434.Sthe_1983	2.365e-52	195.0	2BHS8@1|root,33DMI@2|Bacteria,2GBGN@200795|Chloroflexi,27YQG@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
MMS3_k127_410376_1	479434.Sthe_1982	2.814e-75	258.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi,27Y9N@189775|Thermomicrobia	189775|Thermomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_412623_1	1382356.JQMP01000003_gene1830	3.145e-71	243.0	COG0624@1|root,COG0624@2|Bacteria,2G62C@200795|Chloroflexi,27XWR@189775|Thermomicrobia	189775|Thermomicrobia	E	peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_412623_5	1068980.ARVW01000001_gene1927	3.587e-27	115.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria,4E7KV@85010|Pseudonocardiales	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
MMS3_k127_412623_2	543632.JOJL01000043_gene3768	3.74e-45	166.0	COG3631@1|root,COG3631@2|Bacteria,2IQSN@201174|Actinobacteria,4DGNR@85008|Micromonosporales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMS3_k127_412623_3	1206101.AZXC01000013_gene929	1.347e-36	143.0	COG3832@1|root,COG3832@2|Bacteria,2GSCI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMS3_k127_412623_4	1123023.JIAI01000008_gene1330	1.647e-30	123.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria	201174|Actinobacteria	K	arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
MMS3_k127_412623_0	479434.Sthe_3300	1.324e-159	516.0	COG0665@1|root,COG0665@2|Bacteria,2G86Q@200795|Chloroflexi,27Y37@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
MMS3_k127_4129784_4	67257.JODR01000014_gene5738	1.099e-19	94.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria	201174|Actinobacteria	IQ	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,adh_short
MMS3_k127_4129784_0	479434.Sthe_0078	1.422e-176	572.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	189775|Thermomicrobia	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_4129784_2	1173020.Cha6605_3921	2.295e-34	143.0	COG1309@1|root,COG1309@2|Bacteria,1G0D9@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
MMS3_k127_4129784_3	485913.Krac_5355	4.846e-23	102.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_4129784_1	208439.AJAP_12500	5.224e-56	201.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria,4EFE8@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMS3_k127_4138915_0	886293.Sinac_0946	6.856e-112	366.0	COG1023@1|root,COG1023@2|Bacteria,2IYCD@203682|Planctomycetes	203682|Planctomycetes	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
MMS3_k127_4138915_4	525367.HMPREF0556_11761	0.0001145	48.0	COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli	91061|Bacilli	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
MMS3_k127_4138915_1	357808.RoseRS_1669	8.258e-49	199.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria,2G805@200795|Chloroflexi	200795|Chloroflexi	T	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
MMS3_k127_4138915_2	479434.Sthe_1528	8.635e-35	154.0	COG0726@1|root,COG0726@2|Bacteria,2G76U@200795|Chloroflexi,27Z4V@189775|Thermomicrobia	189775|Thermomicrobia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_4138915_3	479434.Sthe_2748	1.127e-19	91.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	2|Bacteria	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_4139214_8	1382306.JNIM01000001_gene284	5.732e-58	209.0	COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
MMS3_k127_4139214_6	316274.Haur_3823	3.447e-80	276.0	COG0566@1|root,COG0566@2|Bacteria,2G7XK@200795|Chloroflexi,376BA@32061|Chloroflexia	32061|Chloroflexia	H	PFAM tRNA rRNA methyltransferase (SpoU)	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
MMS3_k127_4139214_5	479434.Sthe_0748	1.444e-81	278.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
MMS3_k127_4139214_2	479434.Sthe_0745	1.643e-212	669.0	COG0624@1|root,COG0624@2|Bacteria,2GB9S@200795|Chloroflexi,27YDU@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_4139214_7	311403.Arad_9385	5.191e-63	224.0	COG2227@1|root,COG2227@2|Bacteria,1R7WN@1224|Proteobacteria,2TUV6@28211|Alphaproteobacteria,4BD8R@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMS3_k127_4139214_3	479434.Sthe_0740	3.027e-175	559.0	COG0303@1|root,COG0303@2|Bacteria,2G6AK@200795|Chloroflexi,27Y3T@189775|Thermomicrobia	189775|Thermomicrobia	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
MMS3_k127_4139214_4	479434.Sthe_0734	2.985e-127	412.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi,27XXG@189775|Thermomicrobia	189775|Thermomicrobia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
MMS3_k127_4139214_0	479434.Sthe_0734	1.917e-265	821.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi,27XXG@189775|Thermomicrobia	189775|Thermomicrobia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
MMS3_k127_4139214_1	479434.Sthe_0730	7.271e-218	687.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi,27XUD@189775|Thermomicrobia	189775|Thermomicrobia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
MMS3_k127_4139897_3	479434.Sthe_3416	1.192e-14	74.0	COG2026@1|root,COG2026@2|Bacteria,2G9FJ@200795|Chloroflexi	200795|Chloroflexi	DJ	PFAM plasmid stabilization system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
MMS3_k127_4139897_2	479434.Sthe_3417	3.791e-19	90.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
MMS3_k127_4139897_0	1157640.AQWO01000046_gene3386	1.13e-229	723.0	COG0457@1|root,COG0457@2|Bacteria,2HX8A@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
MMS3_k127_4139897_4	1382304.JNIL01000001_gene1549	3.315e-09	61.0	COG1918@1|root,COG1918@2|Bacteria,1VK8Z@1239|Firmicutes	1239|Firmicutes	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
MMS3_k127_4139897_1	1120972.AUMH01000045_gene409	1.487e-79	272.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,278RB@186823|Alicyclobacillaceae	91061|Bacilli	P	Ferrous iron transport protein B C terminus	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	iSB619.SA_RS13395	FeoB_C,FeoB_N,Gate
MMS3_k127_4148269_1	1254432.SCE1572_51840	1.064e-141	461.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2YTZ3@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.8,1.2.1.85	ko:K00128,ko:K00130,ko:K10217	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00555,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMS3_k127_4148269_2	420246.GTNG_0892	2.359e-102	351.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1WFIH@129337|Geobacillus	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMS3_k127_4148269_0	1120971.AUCA01000024_gene452	7.526e-143	475.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HAIR@91061|Bacilli,2792S@186823|Alicyclobacillaceae	91061|Bacilli	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1,Urease_alpha
MMS3_k127_4151698_1	326427.Cagg_0222	4.631e-155	504.0	COG0445@1|root,COG0445@2|Bacteria,2G629@200795|Chloroflexi,376CM@32061|Chloroflexia	32061|Chloroflexia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
MMS3_k127_4151698_2	479434.Sthe_1642	6.174e-123	397.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi,27Y5S@189775|Thermomicrobia	189775|Thermomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_4151698_5	1382356.JQMP01000004_gene329	1.906e-43	164.0	COG0589@1|root,COG0589@2|Bacteria,2G7D7@200795|Chloroflexi,27YGW@189775|Thermomicrobia	189775|Thermomicrobia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_4151698_4	479434.Sthe_1644	1.959e-54	194.0	COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi,27YE9@189775|Thermomicrobia	189775|Thermomicrobia	C	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
MMS3_k127_4151698_3	479434.Sthe_1645	1.259e-110	360.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi,27XTU@189775|Thermomicrobia	189775|Thermomicrobia	P	TrkA-C domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
MMS3_k127_4151698_0	479434.Sthe_1648	1.803e-224	701.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi,27XVS@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
MMS3_k127_4153866_9	2340.JV46_16940	9.718e-07	62.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.2.7.1	ko:K03737,ko:K05337	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
MMS3_k127_4153866_5	1187851.A33M_4209	1.318e-80	296.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
MMS3_k127_4153866_4	1049564.TevJSym_bb00040	3.056e-99	335.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_4153866_1	1049564.TevJSym_bb00050	4.444e-222	707.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
MMS3_k127_4153866_0	1187851.A33M_4208	2.881e-222	699.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3FCY5@34008|Rhodovulum	28211|Alphaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
MMS3_k127_4153866_3	1187851.A33M_4207	2.989e-144	462.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	gltA	-	1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1,Pyr_redox_2
MMS3_k127_4153866_6	266117.Rxyl_0187	5.394e-76	261.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CQ94@84995|Rubrobacteria	84995|Rubrobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_4153866_7	1078020.KEK_04957	5.042e-49	193.0	COG5002@1|root,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria,23FHB@1762|Mycobacteriaceae	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_4153866_2	479434.Sthe_1193	4.971e-209	658.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi,27XRP@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMS3_k127_4153866_8	994479.GL877882_gene6893	2.507e-20	94.0	COG1216@1|root,COG1216@2|Bacteria,2GX95@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
MMS3_k127_4156430_0	479434.Sthe_0589	2.655e-276	859.0	COG0664@1|root,COG0664@2|Bacteria,2G63K@200795|Chloroflexi,27YV2@189775|Thermomicrobia	189775|Thermomicrobia	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4161407_0	309801.trd_0078	3.605e-71	250.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi,27YZ7@189775|Thermomicrobia	189775|Thermomicrobia	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
MMS3_k127_4161407_1	1283283.ATXA01000016_gene66	3.504e-63	223.0	COG3832@1|root,COG3832@2|Bacteria,2IMFE@201174|Actinobacteria,4EVNW@85013|Frankiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMS3_k127_4161407_3	512565.AMIS_11190	2.053e-50	181.0	COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4DG2M@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
MMS3_k127_4161407_2	479434.Sthe_2035	9.934e-52	193.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
MMS3_k127_4161407_4	635013.TherJR_2195	1.299e-24	108.0	COG3682@1|root,COG3682@2|Bacteria,1VGZ0@1239|Firmicutes,24SJ1@186801|Clostridia,265ZK@186807|Peptococcaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
MMS3_k127_4161407_5	469383.Cwoe_2482	1.68e-12	78.0	COG0501@1|root,COG0501@2|Bacteria,2GQJY@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
MMS3_k127_4162524_1	479434.Sthe_1511	1.964e-39	151.0	COG1173@1|root,COG1173@2|Bacteria,2G841@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_4162524_0	309801.trd_1331	2.632e-121	409.0	COG0405@1|root,COG0405@2|Bacteria,2GABC@200795|Chloroflexi,27XH8@189775|Thermomicrobia	189775|Thermomicrobia	E	TIGRFAM gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_4162524_3	304371.MCP_0718	2.01e-23	115.0	COG1456@1|root,arCOG06909@2157|Archaea,2Y2FW@28890|Euryarchaeota,2NAAQ@224756|Methanomicrobia	224756|Methanomicrobia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD
MMS3_k127_4162524_2	196490.AUEZ01000113_gene476	3.58e-24	117.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.103,2.1.1.163,2.1.1.201	ko:K03183,ko:K05929	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00116,M00117	R02037,R04990,R04993,R06859,R06868,R06869,R08774,R09736	RC00003,RC00060,RC00181,RC00496,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
MMS3_k127_4162524_4	479434.Sthe_2595	4.877e-12	66.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	2|Bacteria	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
MMS3_k127_4165356_2	479434.Sthe_1775	9.89e-114	372.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_4165356_0	479434.Sthe_1776	0.0	1114.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
MMS3_k127_4165356_1	287986.DV20_11390	2.548e-115	378.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4E22V@85010|Pseudonocardiales	201174|Actinobacteria	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_4185717_1	479434.Sthe_1845	1.2e-134	431.0	COG1508@1|root,COG1508@2|Bacteria,2G5VM@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
MMS3_k127_4185717_0	479434.Sthe_1847	4.299e-139	447.0	COG0540@1|root,COG0540@2|Bacteria,2G6GU@200795|Chloroflexi,27XZF@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMS3_k127_4185717_2	479434.Sthe_1849	1.167e-130	425.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27Y3K@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMS3_k127_4185717_3	479434.Sthe_1850	3.033e-90	304.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi,27XPG@189775|Thermomicrobia	189775|Thermomicrobia	L	Rad50 zinc hook motif	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
MMS3_k127_4197013_3	479434.Sthe_2558	8.887e-143	473.0	COG1971@1|root,COG5305@1|root,COG1971@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp,PMT_2
MMS3_k127_4197013_7	479434.Sthe_2551	2.409e-69	242.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi,27Y6C@189775|Thermomicrobia	189775|Thermomicrobia	F	Uracil phosphoribosyltransferase	-	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
MMS3_k127_4197013_4	479434.Sthe_0166	1.368e-115	381.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi,27XWD@189775|Thermomicrobia	189775|Thermomicrobia	U	PFAM 60 kDa inner membrane insertion protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
MMS3_k127_4197013_0	479434.Sthe_2549	4.052e-219	699.0	COG1404@1|root,COG1404@2|Bacteria,2GBHQ@200795|Chloroflexi,27XI4@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
MMS3_k127_4197013_2	479434.Sthe_2547	6.102e-155	507.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,Peptidase_M6
MMS3_k127_4197013_6	1532558.JL39_09155	2.279e-83	290.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2TRJN@28211|Alphaproteobacteria,4BC1F@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_4197013_5	479434.Sthe_2546	8.852e-90	312.0	COG2234@1|root,COG2234@2|Bacteria,2G8I9@200795|Chloroflexi,27Z9R@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_4197013_8	1366050.N234_11215	5.095e-07	62.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VITW@28216|Betaproteobacteria,1K13H@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	ydhP	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
MMS3_k127_4197013_1	479434.Sthe_2529	1.594e-216	679.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi	200795|Chloroflexi	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_4203416_1	1121272.KB903249_gene1627	8.634e-131	426.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria,2HU5Q@201174|Actinobacteria,4DBMT@85008|Micromonosporales	201174|Actinobacteria	I	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
MMS3_k127_4203416_4	1121378.KB899724_gene54	6.042e-43	167.0	COG2267@1|root,COG2267@2|Bacteria,1WNCY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_4203416_2	479434.Sthe_2313	5.791e-104	351.0	COG0665@1|root,COG0665@2|Bacteria,2G6QE@200795|Chloroflexi,27Y6M@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_4203416_6	1122223.KB890700_gene1941	1.774e-30	124.0	COG0239@1|root,COG0239@2|Bacteria,1WK4E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
MMS3_k127_4203416_7	1121441.AUCX01000013_gene1912	3.584e-23	104.0	COG1993@1|root,COG1993@2|Bacteria,1N0EM@1224|Proteobacteria,42TZK@68525|delta/epsilon subdivisions,2WQ2E@28221|Deltaproteobacteria,2M86Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
MMS3_k127_4203416_5	349161.Dred_3064	3.633e-41	169.0	COG1808@1|root,COG1808@2|Bacteria,1TRFZ@1239|Firmicutes,24PYJ@186801|Clostridia	186801|Clostridia	S	Hydrophobic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
MMS3_k127_4203416_3	1541065.JRFE01000022_gene4145	2.976e-77	271.0	COG0726@1|root,COG0726@2|Bacteria,1GEGH@1117|Cyanobacteria,3VNH8@52604|Pleurocapsales	1117|Cyanobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMS3_k127_4203416_8	1278307.KB907016_gene3433	2.92e-22	107.0	COG2267@1|root,COG2267@2|Bacteria,1R299@1224|Proteobacteria,1T5JY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_4203416_0	479434.Sthe_2480	0.0	1142.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
MMS3_k127_4228958_11	1173022.Cri9333_2993	0.0001143	54.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria,1HEV5@1150|Oscillatoriales	1117|Cyanobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
MMS3_k127_4228958_1	316067.Geob_3236	2.653e-135	462.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
MMS3_k127_4228958_4	479434.Sthe_0091	1.352e-61	216.0	COG1607@1|root,COG1607@2|Bacteria,2G7A6@200795|Chloroflexi	200795|Chloroflexi	I	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_4228958_3	479434.Sthe_3514	1.204e-97	326.0	COG0561@1|root,COG0561@2|Bacteria,2G74S@200795|Chloroflexi,27YAH@189775|Thermomicrobia	189775|Thermomicrobia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
MMS3_k127_4228958_10	1463864.JOGO01000035_gene1289	2.468e-26	117.0	COG1011@1|root,COG1011@2|Bacteria,2IG88@201174|Actinobacteria	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase_like
MMS3_k127_4228958_0	479434.Sthe_3513	2.704e-260	816.0	COG5309@1|root,COG5309@2|Bacteria,2G8VX@200795|Chloroflexi,27XUZ@189775|Thermomicrobia	189775|Thermomicrobia	G	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
MMS3_k127_4228958_6	1176165.CAJD01000019_gene1512	1.873e-54	202.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria	201174|Actinobacteria	C	Acetamidase formamidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
MMS3_k127_4228958_5	309801.trd_A0397	2.023e-60	219.0	COG1387@1|root,COG1387@2|Bacteria,2G8ST@200795|Chloroflexi,27ZB2@189775|Thermomicrobia	189775|Thermomicrobia	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
MMS3_k127_4228958_7	479434.Sthe_3512	6.629e-49	181.0	COG0346@1|root,COG0346@2|Bacteria,2GB9Q@200795|Chloroflexi,27YDI@189775|Thermomicrobia	189775|Thermomicrobia	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_4228958_9	479434.Sthe_3511	2.12e-32	131.0	COG2318@1|root,COG2318@2|Bacteria,2GBBU@200795|Chloroflexi,27YPX@189775|Thermomicrobia	189775|Thermomicrobia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_4228958_2	479434.Sthe_3510	1.137e-99	332.0	COG2141@1|root,COG2141@2|Bacteria,2GB9A@200795|Chloroflexi,27Y8J@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_4228958_8	479434.Sthe_3508	4.474e-42	158.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_4230441_0	479434.Sthe_3098	3.583e-144	462.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi,27XYY@189775|Thermomicrobia	189775|Thermomicrobia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
MMS3_k127_4230441_6	479434.Sthe_3097	2.911e-51	186.0	2BQKI@1|root,32JGJ@2|Bacteria,2G9SN@200795|Chloroflexi,27YIJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_4230441_5	479434.Sthe_3094	2.292e-60	215.0	COG4720@1|root,COG4720@2|Bacteria,2GA0R@200795|Chloroflexi,27YG3@189775|Thermomicrobia	189775|Thermomicrobia	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF-ribofla_trS
MMS3_k127_4230441_2	479434.Sthe_3089	1.093e-115	380.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,27YU5@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
MMS3_k127_4230441_4	479434.Sthe_3089	3.179e-96	322.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,27YU5@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
MMS3_k127_4230441_3	479434.Sthe_3088	4.085e-100	335.0	COG0619@1|root,COG0619@2|Bacteria,2G7IA@200795|Chloroflexi,27Z55@189775|Thermomicrobia	189775|Thermomicrobia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
MMS3_k127_4230441_1	479434.Sthe_3087	8.616e-124	410.0	COG0787@1|root,COG0787@2|Bacteria,2G66N@200795|Chloroflexi,27XRR@189775|Thermomicrobia	189775|Thermomicrobia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
MMS3_k127_4230441_7	28444.JODQ01000006_gene151	4.178e-44	167.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	2.7.13.3,5.3.1.13	ko:K06041,ko:K11527	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01001,ko01005,ko02022	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
MMS3_k127_4230441_8	28444.JODQ01000006_gene152	7.052e-42	160.0	COG0369@1|root,COG1716@1|root,COG5274@1|root,COG0369@2|Bacteria,COG1716@2|Bacteria,COG5274@2|Bacteria,2I3UN@201174|Actinobacteria	201174|Actinobacteria	P	ATPase activity	-	-	1.14.14.1,1.6.2.4	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko00199,ko01000	-	-	-	NAD_binding_1
MMS3_k127_4253115_1	656024.FsymDg_1729	6.326e-33	128.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4EUYD@85013|Frankiales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_4253115_0	1382356.JQMP01000003_gene1387	9.378e-103	344.0	COG3342@1|root,COG3342@2|Bacteria,2G663@200795|Chloroflexi,27Y6W@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
MMS3_k127_4268229_0	1340434.AXVA01000003_gene2107	2.83e-55	203.0	COG0596@1|root,COG0596@2|Bacteria,1U3F6@1239|Firmicutes,4HFV2@91061|Bacilli,1ZCQM@1386|Bacillus	91061|Bacilli	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
MMS3_k127_4268229_2	591158.SSMG_08190	1.114e-07	60.0	COG0125@1|root,COG3173@1|root,COG0125@2|Bacteria,COG3173@2|Bacteria,2I5UN@201174|Actinobacteria	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	APH,Thymidylate_kin
MMS3_k127_4268229_1	298653.Franean1_2827	3.091e-19	96.0	COG3173@1|root,COG3173@2|Bacteria,2I5UN@201174|Actinobacteria	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	APH,Thymidylate_kin
MMS3_k127_4269888_0	479434.Sthe_0337	0.0	1670.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,27XEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Anticodon-binding domain of tRNA	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
MMS3_k127_427223_7	479434.Sthe_2589	2.544e-88	315.0	COG0419@1|root,COG1131@1|root,COG0419@2|Bacteria,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	bcrA	-	-	ko:K01990,ko:K13582,ko:K20459,ko:K20491	ko02010,ko02020,ko02024,ko04112,map02010,map02020,map02024,map04112	M00254,M00813,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5,3.A.1.124.6	-	-	ABC_tran
MMS3_k127_427223_4	479434.Sthe_2590	9.394e-131	430.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
MMS3_k127_427223_5	479434.Sthe_3336	1.083e-120	399.0	COG0477@1|root,COG2814@2|Bacteria,2G90P@200795|Chloroflexi	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_427223_6	547559.Nmag_0093	5.09e-90	315.0	COG1167@1|root,arCOG00492@2157|Archaea,2XVD6@28890|Euryarchaeota,23SWW@183963|Halobacteria	183963|Halobacteria	K	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
MMS3_k127_427223_0	479434.Sthe_2564	3.102e-175	556.0	COG0492@1|root,COG0492@2|Bacteria,2GB7X@200795|Chloroflexi,27XWC@189775|Thermomicrobia	189775|Thermomicrobia	C	Ferredoxin--NADP reductase	-	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
MMS3_k127_427223_2	479434.Sthe_1894	2.895e-140	451.0	COG0601@1|root,COG0601@2|Bacteria,2G61A@200795|Chloroflexi,27XMA@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_427223_3	479434.Sthe_1895	1.027e-135	438.0	COG1173@1|root,COG1173@2|Bacteria,2G612@200795|Chloroflexi,27XHC@189775|Thermomicrobia	189775|Thermomicrobia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
MMS3_k127_427223_1	479434.Sthe_1896	7.397e-143	467.0	COG4166@1|root,COG4166@2|Bacteria,2G8A0@200795|Chloroflexi,27XKE@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_430157_7	479434.Sthe_3521	1.705e-40	160.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMS3_k127_430157_4	479434.Sthe_3522	2.768e-98	334.0	COG0668@1|root,COG0668@2|Bacteria,2G75W@200795|Chloroflexi,27Y8R@189775|Thermomicrobia	189775|Thermomicrobia	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
MMS3_k127_430157_0	1382356.JQMP01000003_gene2056	2.334e-192	613.0	COG1653@1|root,COG1653@2|Bacteria,2G6WT@200795|Chloroflexi,27Z46@189775|Thermomicrobia	189775|Thermomicrobia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10236	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	SBP_bac_1
MMS3_k127_430157_1	479434.Sthe_1812	2.612e-134	434.0	COG1175@1|root,COG1175@2|Bacteria,2G8HC@200795|Chloroflexi,27YT8@189775|Thermomicrobia	189775|Thermomicrobia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10237	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	BPD_transp_1
MMS3_k127_430157_2	1382356.JQMP01000003_gene2058	3.863e-128	418.0	COG0395@1|root,COG0395@2|Bacteria,2G6M8@200795|Chloroflexi,27Z03@189775|Thermomicrobia	189775|Thermomicrobia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10238	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	BPD_transp_1
MMS3_k127_430157_3	309801.trd_0072	1.663e-112	373.0	COG0524@1|root,COG0524@2|Bacteria,2G7YB@200795|Chloroflexi,27YGK@189775|Thermomicrobia	189775|Thermomicrobia	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
MMS3_k127_430157_6	1122223.KB890687_gene2590	6.639e-43	161.0	COG2050@1|root,COG2050@2|Bacteria,1WJS6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMS3_k127_430157_5	1121472.AQWN01000012_gene998	9.62e-47	175.0	COG1309@1|root,COG1309@2|Bacteria,1VE1K@1239|Firmicutes,25AKM@186801|Clostridia,26535@186807|Peptococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_4305148_1	479434.Sthe_0466	2.517e-84	283.0	COG0423@1|root,COG0423@2|Bacteria,2G62M@200795|Chloroflexi,27XGU@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of glycine to tRNA(Gly)	-	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
MMS3_k127_4305148_0	479434.Sthe_0465	1.895e-123	405.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi,27Y19@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMS3_k127_431275_6	661367.LLO_0983	2.297e-87	300.0	COG2334@1|root,COG2334@2|Bacteria,1R9W9@1224|Proteobacteria,1SGNX@1236|Gammaproteobacteria,1JCMB@118969|Legionellales	118969|Legionellales	S	Phosphotransferase enzyme family	aph	-	-	ko:K18844	-	-	-	-	ko00000,ko01504	-	-	-	APH
MMS3_k127_431275_12	1120949.KB903317_gene1645	2.271e-52	198.0	COG0463@1|root,COG1287@1|root,COG0463@2|Bacteria,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
MMS3_k127_431275_8	1968.JOEV01000025_gene5015	2.813e-80	271.0	COG0412@1|root,COG0412@2|Bacteria,2GTZG@201174|Actinobacteria	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
MMS3_k127_431275_1	479434.Sthe_0750	2.95e-137	451.0	COG5002@1|root,COG5002@2|Bacteria,2G6F5@200795|Chloroflexi,27Z71@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMS3_k127_431275_5	479434.Sthe_0751	1.094e-101	335.0	COG0745@1|root,COG0745@2|Bacteria,2GABY@200795|Chloroflexi,27Z4B@189775|Thermomicrobia	189775|Thermomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_431275_3	479434.Sthe_3346	3.582e-111	373.0	COG0265@1|root,COG0265@2|Bacteria,2G8RK@200795|Chloroflexi,27Y6G@189775|Thermomicrobia	189775|Thermomicrobia	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
MMS3_k127_431275_4	1089546.AQUI01000002_gene245	1.232e-107	356.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_431275_9	861299.J421_0534	1.764e-79	268.0	COG4032@1|root,COG4032@2|Bacteria	2|Bacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
MMS3_k127_431275_7	861299.J421_0533	1.325e-84	287.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.1.79	ko:K13039	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMS3_k127_431275_2	861299.J421_0532	5.39e-122	395.0	COG1878@1|root,COG1878@2|Bacteria,1ZV5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
MMS3_k127_431275_0	1206731.BAGB01000023_gene1222	4.121e-189	604.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4G5I0@85025|Nocardiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_431275_10	1501230.ET33_24170	7.136e-65	227.0	COG1309@1|root,COG1309@2|Bacteria,1VHN0@1239|Firmicutes,4HNH8@91061|Bacilli,26VSH@186822|Paenibacillaceae	91061|Bacilli	K	TetR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_431275_14	211114.JOEF01000007_gene1031	7.109e-08	57.0	COG3899@1|root,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4E3EA@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,GerE,Guanylate_cyc,Trans_reg_C
MMS3_k127_4322150_0	675635.Psed_6013	3.594e-45	174.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4DZX8@85010|Pseudonocardiales	201174|Actinobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_4322158_5	479434.Sthe_3051	5.242e-22	99.0	COG0384@1|root,COG0384@2|Bacteria,2G7U6@200795|Chloroflexi,27ZAQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
MMS3_k127_4322158_1	479434.Sthe_3260	1.949e-137	443.0	COG1194@1|root,COG1194@2|Bacteria,2G62P@200795|Chloroflexi,27XJQ@189775|Thermomicrobia	189775|Thermomicrobia	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMS3_k127_4322158_0	479434.Sthe_3259	1.931e-212	665.0	COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi,27XN0@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
MMS3_k127_4322158_2	1906.SFRA_06035	1.98e-44	173.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_4322158_4	485913.Krac_9334	5.54e-36	146.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
MMS3_k127_433540_3	485913.Krac_5673	4.619e-09	57.0	COG0262@1|root,COG0262@2|Bacteria,2G8UG@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMS3_k127_433540_2	498848.TaqDRAFT_5037	6.994e-16	80.0	COG2361@1|root,COG2361@2|Bacteria,1WKJ0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function DUF86	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	DUF86,NTP_transf_2
MMS3_k127_433540_1	272134.KB731324_gene6581	2.109e-21	96.0	COG1669@1|root,COG1669@2|Bacteria,1G7R5@1117|Cyanobacteria,1HCID@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
MMS3_k127_433540_0	479434.Sthe_2363	4.359e-215	676.0	COG0209@1|root,COG0209@2|Bacteria,2G8RN@200795|Chloroflexi,27Y2V@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
MMS3_k127_451789_7	479434.Sthe_0530	6.387e-43	159.0	COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.8	ko:K00255,ko:K11731	ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754,R08089	RC00052,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_451789_4	479434.Sthe_0531	1.552e-146	477.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,27Y45@189775|Thermomicrobia	2|Bacteria	C	Acyl- CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_451789_5	479434.Sthe_0532	6.291e-72	246.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
MMS3_k127_451789_3	1121468.AUBR01000028_gene1511	1.097e-146	492.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,42FXS@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
MMS3_k127_451789_6	479434.Sthe_0534	2.924e-51	188.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMS3_k127_451789_2	479434.Sthe_0535	4.594e-148	475.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,27XUY@189775|Thermomicrobia	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_451789_1	479434.Sthe_0537	2.71e-159	507.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,27XUY@189775|Thermomicrobia	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_451789_0	479434.Sthe_0538	1.844e-202	635.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMS3_k127_458442_4	479434.Sthe_0309	1.855e-13	71.0	COG4166@1|root,COG4166@2|Bacteria,2G8A0@200795|Chloroflexi,27XKE@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_458442_1	479434.Sthe_0308	1.287e-162	516.0	COG0115@1|root,COG0115@2|Bacteria,2GAM4@200795|Chloroflexi,27XJA@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMS3_k127_458442_0	479434.Sthe_0306	1.587e-212	675.0	COG0001@1|root,COG0001@2|Bacteria,2G7UK@200795|Chloroflexi,27XN6@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_458442_2	309801.trd_1612	4.448e-112	371.0	COG2515@1|root,COG2515@2|Bacteria,2G6PX@200795|Chloroflexi,27YZ5@189775|Thermomicrobia	189775|Thermomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
MMS3_k127_458442_3	479434.Sthe_0303	3.909e-75	262.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi,27XP2@189775|Thermomicrobia	189775|Thermomicrobia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
MMS3_k127_48638_0	479434.Sthe_3242	3.494e-235	752.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
MMS3_k127_48638_1	377629.TERTU_0539	1.002e-53	201.0	COG3613@1|root,COG3613@2|Bacteria,1NBEC@1224|Proteobacteria	1224|Proteobacteria	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_490100_2	196490.AUEZ01000027_gene1688	3.315e-13	72.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,3JVM1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	MA20_41440	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
MMS3_k127_490100_0	479434.Sthe_1009	8.208e-240	756.0	COG0028@1|root,COG0028@2|Bacteria,2G810@200795|Chloroflexi,27Y11@189775|Thermomicrobia	189775|Thermomicrobia	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMS3_k127_490100_1	1382356.JQMP01000003_gene2028	2.607e-28	118.0	COG1376@1|root,COG1376@2|Bacteria,2G8JH@200795|Chloroflexi,27XUR@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_495184_6	479435.Kfla_1082	1.212e-25	119.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_495184_3	479434.Sthe_1133	4.69e-49	198.0	2DYB6@1|root,3490S@2|Bacteria	479434.Sthe_1133|-	S	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_495184_11	1185876.BN8_01787	3.831e-08	66.0	COG3227@1|root,COG3405@1|root,COG3534@1|root,COG3227@2|Bacteria,COG3405@2|Bacteria,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	2.4.1.12,3.2.1.156,3.2.1.4	ko:K00694,ko:K15531,ko:K20542	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GH8,GT2	-	Dockerin_1,Glyco_hydro_8,fn3
MMS3_k127_495184_2	485913.Krac_1392	2.319e-49	182.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_495184_5	55952.BU52_16100	1.315e-27	128.0	COG3210@1|root,COG3210@2|Bacteria,2IPU7@201174|Actinobacteria	201174|Actinobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_495184_10	485913.Krac_9331	4.038e-12	72.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMS3_k127_495184_8	219305.MCAG_04278	1.756e-23	109.0	COG1051@1|root,COG1051@2|Bacteria,2I40B@201174|Actinobacteria,4DE5S@85008|Micromonosporales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_495184_4	927677.ALVU02000001_gene2473	9.125e-38	145.0	COG3339@1|root,COG3339@2|Bacteria,1G7DF@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
MMS3_k127_495184_0	1101188.KI912155_gene1035	4.981e-68	237.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
MMS3_k127_495184_1	485913.Krac_12385	3.03e-50	184.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Glycos_transf_1,Glycos_transf_2,MethyTransf_Reg,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,TPR_2
MMS3_k127_510661_1	485913.Krac_2637	2.526e-163	527.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
MMS3_k127_510661_5	485913.Krac_2638	4.805e-08	58.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
MMS3_k127_510661_3	485913.Krac_2639	2.657e-28	119.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
MMS3_k127_510661_0	485913.Krac_2641	2.191e-185	592.0	COG1233@1|root,COG1233@2|Bacteria,2G60T@200795|Chloroflexi	200795|Chloroflexi	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
MMS3_k127_510661_4	309801.trd_1534	1.681e-09	59.0	COG2010@1|root,COG2010@2|Bacteria,2G9FK@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_513389_3	309801.trd_1617	3.798e-95	317.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi,27XZG@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
MMS3_k127_513389_1	479434.Sthe_0380	5.452e-200	639.0	COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi,27XJZ@189775|Thermomicrobia	189775|Thermomicrobia	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
MMS3_k127_513389_2	309801.trd_1615	1.102e-96	321.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi,27XXM@189775|Thermomicrobia	189775|Thermomicrobia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
MMS3_k127_513389_4	1382356.JQMP01000004_gene676	5.677e-69	238.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi,27YB2@189775|Thermomicrobia	189775|Thermomicrobia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
MMS3_k127_513389_0	479434.Sthe_0303	1.327e-242	759.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi,27XP2@189775|Thermomicrobia	189775|Thermomicrobia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
MMS3_k127_518229_1	479434.Sthe_2125	5.032e-136	437.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27YYN@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMS3_k127_518229_0	479434.Sthe_2126	1.661e-149	478.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi,27YUB@189775|Thermomicrobia	189775|Thermomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
MMS3_k127_518229_2	1122915.AUGY01000002_gene7449	1.756e-24	118.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
MMS3_k127_527760_3	1382356.JQMP01000001_gene1078	1.318e-14	74.0	COG2608@1|root,COG2608@2|Bacteria,2G7DX@200795|Chloroflexi,27YP3@189775|Thermomicrobia	189775|Thermomicrobia	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
MMS3_k127_527760_0	479434.Sthe_3314	5.825e-127	417.0	COG1073@1|root,COG1073@2|Bacteria,2G95Q@200795|Chloroflexi,27XU7@189775|Thermomicrobia	189775|Thermomicrobia	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_527760_1	479434.Sthe_1545	5.945e-85	286.0	COG5553@1|root,COG5553@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
MMS3_k127_527760_2	880073.Calab_0293	5.028e-74	263.0	COG0520@1|root,COG0520@2|Bacteria,2NP4B@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMS3_k127_527881_5	309801.trd_0373	2.863e-08	65.0	COG4454@1|root,COG4454@2|Bacteria,2GA6H@200795|Chloroflexi,27YMB@189775|Thermomicrobia	189775|Thermomicrobia	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
MMS3_k127_527881_3	479434.Sthe_0203	1.05e-18	97.0	COG4454@1|root,COG4454@2|Bacteria,2GA6H@200795|Chloroflexi,27YMB@189775|Thermomicrobia	189775|Thermomicrobia	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
MMS3_k127_527881_0	1128421.JAGA01000003_gene3692	3.729e-106	366.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
MMS3_k127_527881_2	926560.KE387027_gene510	6.443e-44	164.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
MMS3_k127_527881_4	324602.Caur_2944	3.44e-09	65.0	2DR9N@1|root,33ATC@2|Bacteria,2G9JG@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
MMS3_k127_527881_1	479434.Sthe_0128	1.296e-94	319.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMS3_k127_543262_4	479434.Sthe_0197	6.6e-115	376.0	COG1235@1|root,COG1235@2|Bacteria,2G8BU@200795|Chloroflexi,27Y03@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
MMS3_k127_543262_2	479434.Sthe_0196	4.007e-125	408.0	COG0491@1|root,COG0491@2|Bacteria,2G6KC@200795|Chloroflexi,27Y6V@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_543262_7	479434.Sthe_0195	3.647e-53	196.0	2C5T0@1|root,337HV@2|Bacteria,2G9CN@200795|Chloroflexi,27Y76@189775|Thermomicrobia	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_543262_1	1462526.BN990_04378	3.722e-133	439.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,4C6MX@84406|Virgibacillus	91061|Bacilli	S	Peptidase dimerisation domain	-	-	-	ko:K12941,ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_543262_8	485913.Krac_10783	2.215e-44	170.0	COG3382@1|root,COG3382@2|Bacteria,2G96A@200795|Chloroflexi	200795|Chloroflexi	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
MMS3_k127_543262_3	479434.Sthe_1775	1.272e-117	384.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_543262_5	443255.SCLAV_2727	5.106e-102	342.0	COG2159@1|root,COG2159@2|Bacteria,2HEB4@201174|Actinobacteria	201174|Actinobacteria	CH	amidohydrolase	-	-	4.1.1.45,4.1.1.52	ko:K03392,ko:K22213	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
MMS3_k127_543262_0	749927.AMED_4144	1.667e-164	533.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4E93P@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_543262_6	479434.Sthe_2041	2.776e-78	265.0	COG2936@1|root,COG2936@2|Bacteria,2G86S@200795|Chloroflexi	200795|Chloroflexi	S	X-Pro dipeptidyl-peptidase domain protein	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
MMS3_k127_543954_5	1476583.DEIPH_ctg050orf0040	6.892e-38	146.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC,TusA
MMS3_k127_543954_7	479434.Sthe_0348	2.823e-26	110.0	2DY8M@1|root,348MZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_543954_1	316274.Haur_0153	3.311e-91	316.0	COG0443@1|root,COG0443@2|Bacteria,2GBRB@200795|Chloroflexi,3768Q@32061|Chloroflexia	32061|Chloroflexia	O	Hsp70 protein	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
MMS3_k127_543954_2	1341151.ASZU01000015_gene2132	8.652e-90	306.0	COG3173@1|root,COG3173@2|Bacteria,1UIXX@1239|Firmicutes,4ISW9@91061|Bacilli	91061|Bacilli	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMS3_k127_543954_0	390989.JOEG01000041_gene2934	8.78e-157	524.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4DBG8@85008|Micromonosporales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
MMS3_k127_543954_4	675635.Psed_6033	6.622e-54	194.0	COG3631@1|root,COG3631@2|Bacteria,2GR1G@201174|Actinobacteria,4EDKX@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMS3_k127_543954_6	485913.Krac_3174	2.948e-32	131.0	COG0617@1|root,COG0617@2|Bacteria,2G8X7@200795|Chloroflexi	200795|Chloroflexi	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	NTP_transf_5
MMS3_k127_543954_8	350054.Mflv_5589	0.0001911	49.0	COG0617@1|root,COG0617@2|Bacteria,2IFKR@201174|Actinobacteria	201174|Actinobacteria	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	Aminoglyc_resit,NTP_transf_5
MMS3_k127_543954_3	479434.Sthe_2605	2.723e-70	246.0	COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi,27Z4D@189775|Thermomicrobia	189775|Thermomicrobia	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
MMS3_k127_547520_0	479434.Sthe_1719	1.79e-146	476.0	COG1061@1|root,COG1061@2|Bacteria,2G861@200795|Chloroflexi	200795|Chloroflexi	L	type III restriction protein res subunit	-	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
MMS3_k127_547520_1	479434.Sthe_1720	1.928e-79	270.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
MMS3_k127_557358_5	479434.Sthe_0219	2.122e-70	242.0	COG4992@1|root,COG4992@2|Bacteria,2G5SG@200795|Chloroflexi,27XJF@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMS3_k127_557358_3	479434.Sthe_0218	7.176e-124	402.0	COG0548@1|root,COG0548@2|Bacteria,2G5WV@200795|Chloroflexi,27XZ2@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the acetylglutamate kinase family. LysZ subfamily	-	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
MMS3_k127_557358_0	479434.Sthe_0216	1.552e-189	595.0	COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi,27XMI@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde	-	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMS3_k127_557358_2	479434.Sthe_0215	6.911e-129	421.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi,27XZX@189775|Thermomicrobia	189775|Thermomicrobia	HJ	RimK-like ATP-grasp domain	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
MMS3_k127_557358_1	479434.Sthe_0214	1.043e-148	479.0	COG0624@1|root,COG0624@2|Bacteria,2G61X@200795|Chloroflexi,27XIT@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	Peptidase_M20
MMS3_k127_557358_4	479434.Sthe_0213	2.048e-85	293.0	COG0189@1|root,COG0189@2|Bacteria,2GA33@200795|Chloroflexi,27YBN@189775|Thermomicrobia	189775|Thermomicrobia	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
MMS3_k127_557358_8	479434.Sthe_0212	1.006e-22	98.0	2DRHT@1|root,33BTG@2|Bacteria,2G7I1@200795|Chloroflexi,27YR7@189775|Thermomicrobia	189775|Thermomicrobia	S	TIGRFAM lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
MMS3_k127_557358_6	1089545.KB913037_gene5363	5.333e-27	116.0	COG2453@1|root,COG2453@2|Bacteria,2IHXA@201174|Actinobacteria,4E5XY@85010|Pseudonocardiales	201174|Actinobacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase
MMS3_k127_557358_7	196162.Noca_4966	1.626e-23	101.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
MMS3_k127_5620_3	479434.Sthe_0887	3.249e-49	181.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi,27YG2@189775|Thermomicrobia	189775|Thermomicrobia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
MMS3_k127_5620_0	479434.Sthe_0888	3.663e-272	858.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi,27XNG@189775|Thermomicrobia	189775|Thermomicrobia	S	7TM-HD extracellular	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
MMS3_k127_5620_4	1196324.A374_10735	1.495e-19	93.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli	91061|Bacilli	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
MMS3_k127_5620_2	479434.Sthe_0890	1.688e-116	385.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi,27Z3C@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_5620_1	479434.Sthe_0891	1.172e-162	525.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2G6DU@200795|Chloroflexi,27XMX@189775|Thermomicrobia	189775|Thermomicrobia	S	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
MMS3_k127_5648_3	1123023.JIAI01000006_gene419	3.519e-90	331.0	COG0305@1|root,COG0305@2|Bacteria,2I62I@201174|Actinobacteria,4E8JS@85010|Pseudonocardiales	201174|Actinobacteria	L	Protein of unknown function (DUF3987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3987,DnaB
MMS3_k127_5648_4	429009.Adeg_1371	5.87e-71	271.0	COG1241@1|root,COG1241@2|Bacteria,1VC38@1239|Firmicutes,25F2C@186801|Clostridia	186801|Clostridia	L	Phage plasmid primase P4 family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_5648_8	326424.FRAAL1735	9.26e-07	55.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
MMS3_k127_5648_9	455632.SGR_4672	2.032e-05	55.0	2E1W8@1|root,32X5F@2|Bacteria,2I4GM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
MMS3_k127_5648_1	479434.Sthe_2831	2.802e-140	454.0	COG0582@1|root,COG0582@2|Bacteria,2G7XX@200795|Chloroflexi,27YAP@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
MMS3_k127_5648_6	370438.PTH_2698	1.533e-26	113.0	COG2402@1|root,COG2402@2|Bacteria,1VFYF@1239|Firmicutes,24RM2@186801|Clostridia,266II@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMS3_k127_5648_10	485918.Cpin_3000	4.389e-05	46.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IT98@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
MMS3_k127_5648_7	479434.Sthe_2766	2.689e-22	98.0	2B8Y6@1|root,3228P@2|Bacteria,2GBC3@200795|Chloroflexi,27YQZ@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_5648_5	479434.Sthe_2767	1.757e-60	218.0	COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi,27YMI@189775|Thermomicrobia	189775|Thermomicrobia	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
MMS3_k127_5648_2	479434.Sthe_2768	4.518e-91	304.0	COG3253@1|root,COG3253@2|Bacteria,2G6WY@200795|Chloroflexi,27Y5N@189775|Thermomicrobia	189775|Thermomicrobia	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
MMS3_k127_5648_0	479434.Sthe_2769	0.0	1037.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia	189775|Thermomicrobia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMS3_k127_565448_0	395965.Msil_2986	1.476e-243	761.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria,3NC7S@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2,Pyr_redox_3
MMS3_k127_567873_5	1200792.AKYF01000021_gene5322	2.753e-58	214.0	COG1506@1|root,COG1506@2|Bacteria,1VSK9@1239|Firmicutes,4HU6U@91061|Bacilli,2727N@186822|Paenibacillaceae	91061|Bacilli	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
MMS3_k127_567873_1	479434.Sthe_2347	5.247e-270	845.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	189775|Thermomicrobia	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_567873_3	479432.Sros_1652	7.854e-98	336.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4EIDI@85012|Streptosporangiales	201174|Actinobacteria	T	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
MMS3_k127_567873_4	561175.KB894093_gene2950	1.424e-78	269.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4EI7I@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_567873_0	479434.Sthe_0360	3.976e-297	917.0	COG0318@1|root,COG0318@2|Bacteria,2G5SX@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMS3_k127_567873_2	1291050.JAGE01000001_gene2763	2.792e-218	693.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3WGEU@541000|Ruminococcaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
MMS3_k127_567873_6	1097668.BYI23_C006580	9.248e-14	80.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrB	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,PMSR,Redoxin,SelR,Thioredoxin
MMS3_k127_581489_0	1382356.JQMP01000004_gene274	3.668e-230	730.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi,27Y2G@189775|Thermomicrobia	189775|Thermomicrobia	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_581489_4	479434.Sthe_2898	4.741e-27	114.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
MMS3_k127_581489_1	485913.Krac_11003	2.319e-116	387.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
MMS3_k127_581489_3	1231377.C426_1195	5.18e-36	146.0	2CCI4@1|root,30BPJ@2|Bacteria,1VVCG@1239|Firmicutes,4HWDU@91061|Bacilli,1YCE4@1357|Lactococcus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_581489_2	479434.Sthe_2033	9.731e-38	146.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_591983_0	706587.Desti_3575	1.139e-32	141.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42R6X@68525|delta/epsilon subdivisions,2WMY9@28221|Deltaproteobacteria,2MSBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
MMS3_k127_591983_1	2074.JNYD01000035_gene6719	5.64e-32	134.0	COG0400@1|root,COG0400@2|Bacteria,2IJV2@201174|Actinobacteria	201174|Actinobacteria	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
MMS3_k127_592975_2	479434.Sthe_0639	8.171e-49	188.0	2DBT9@1|root,32TY2@2|Bacteria,2G95T@200795|Chloroflexi,27YPQ@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	-
MMS3_k127_592975_3	479434.Sthe_0639	3.969e-18	90.0	2DBT9@1|root,32TY2@2|Bacteria,2G95T@200795|Chloroflexi,27YPQ@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	-
MMS3_k127_592975_0	1144342.PMI40_02861	6.123e-73	256.0	COG2367@1|root,COG2367@2|Bacteria,1N9HE@1224|Proteobacteria	1224|Proteobacteria	V	Beta-lactamase class A	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMS3_k127_592975_1	255470.cbdbA734	9.236e-57	201.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2G82Q@200795|Chloroflexi,34CXZ@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_624264_3	309801.trd_A0602	2.117e-54	198.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi	200795|Chloroflexi	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
MMS3_k127_624264_2	1382306.JNIM01000001_gene3634	7.989e-68	243.0	COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
MMS3_k127_624264_1	309801.trd_A0604	9.675e-97	324.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
MMS3_k127_624264_4	1173263.Syn7502_03599	1.179e-19	94.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMS3_k127_624264_0	401526.TcarDRAFT_0529	9.458e-100	346.0	COG0044@1|root,COG0044@2|Bacteria,1V0MB@1239|Firmicutes,4H75V@909932|Negativicutes	909932|Negativicutes	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_641238_1	479434.Sthe_1415	3.202e-299	927.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi,27Y17@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
MMS3_k127_641238_24	309801.trd_1221	4.88e-32	132.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi,27YJV@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome C biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
MMS3_k127_641238_25	479434.Sthe_1413	3.844e-30	123.0	2A4RG@1|root,30TCV@2|Bacteria,2GA1J@200795|Chloroflexi,27YN3@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_641238_18	479434.Sthe_1412	2.243e-76	264.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi,27YFZ@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
MMS3_k127_641238_13	479434.Sthe_1411	8.056e-92	307.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi,27YCJ@189775|Thermomicrobia	189775|Thermomicrobia	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
MMS3_k127_641238_11	479434.Sthe_1410	1.745e-97	325.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi,27Y6D@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
MMS3_k127_641238_17	479434.Sthe_2068	5.477e-83	285.0	COG2141@1|root,COG2141@2|Bacteria,2G8NG@200795|Chloroflexi,27Y54@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_641238_14	1128421.JAGA01000001_gene2063	7.356e-90	306.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
MMS3_k127_641238_21	1382356.JQMP01000004_gene235	2.51e-60	213.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi,27YGM@189775|Thermomicrobia	189775|Thermomicrobia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMS3_k127_641238_19	1382356.JQMP01000004_gene234	1.439e-65	230.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi,27YGF@189775|Thermomicrobia	189775|Thermomicrobia	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
MMS3_k127_641238_9	479434.Sthe_1404	1.909e-105	348.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi,27XWT@189775|Thermomicrobia	189775|Thermomicrobia	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
MMS3_k127_641238_22	479434.Sthe_1403	1.841e-47	173.0	COG1975@1|root,COG1975@2|Bacteria,2G6Z8@200795|Chloroflexi,27YDJ@189775|Thermomicrobia	189775|Thermomicrobia	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_CoxI
MMS3_k127_641238_3	479434.Sthe_1402	1.261e-191	605.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,27XNE@189775|Thermomicrobia	189775|Thermomicrobia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
MMS3_k127_641238_4	479434.Sthe_1401	1.904e-161	512.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,27Y33@189775|Thermomicrobia	189775|Thermomicrobia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
MMS3_k127_641238_7	479434.Sthe_1400	9.332e-117	383.0	COG1319@1|root,COG1319@2|Bacteria,2G60Y@200795|Chloroflexi,27XP9@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMS3_k127_641238_0	479434.Sthe_1399	0.0	1213.0	COG1529@1|root,COG1529@2|Bacteria,2G608@200795|Chloroflexi,27XWN@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
MMS3_k127_641238_16	479434.Sthe_1398	1.034e-88	295.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi,27XMB@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMS3_k127_641238_20	479434.Sthe_1397	1.025e-60	214.0	COG3427@1|root,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,27YFP@189775|Thermomicrobia	189775|Thermomicrobia	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
MMS3_k127_641238_15	1382356.JQMP01000004_gene225	1.918e-89	302.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi,27Y8D@189775|Thermomicrobia	189775|Thermomicrobia	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_641238_5	479434.Sthe_1394	3.447e-157	512.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi,27XNF@189775|Thermomicrobia	189775|Thermomicrobia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
MMS3_k127_641238_8	479434.Sthe_1393	4.7e-111	362.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi,27Y58@189775|Thermomicrobia	189775|Thermomicrobia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMS3_k127_641238_12	479434.Sthe_1392	2.854e-97	319.0	COG1219@1|root,COG1219@2|Bacteria,2G661@200795|Chloroflexi,27XW6@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
MMS3_k127_641238_6	479434.Sthe_1392	3.67e-127	409.0	COG1219@1|root,COG1219@2|Bacteria,2G661@200795|Chloroflexi,27XW6@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
MMS3_k127_641238_26	1382356.JQMP01000004_gene221	5.866e-28	119.0	COG4283@1|root,COG4283@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
MMS3_k127_641238_23	1089553.Tph_c01500	3.169e-46	181.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,42G2Z@68295|Thermoanaerobacterales	186801|Clostridia	H	Probable molybdopterin binding domain	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMS3_k127_641238_2	479434.Sthe_1390	2.579e-224	702.0	COG0044@1|root,COG0044@2|Bacteria,2GBDD@200795|Chloroflexi,27YXB@189775|Thermomicrobia	189775|Thermomicrobia	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_641238_10	479434.Sthe_1388	6.756e-104	341.0	COG2738@1|root,COG2738@2|Bacteria,2G6KQ@200795|Chloroflexi,27YW2@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
MMS3_k127_641238_27	479434.Sthe_1387	4.826e-09	59.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi,27XX1@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMS3_k127_64550_0	326424.FRAAL1628	5.755e-76	263.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EUES@85013|Frankiales	201174|Actinobacteria	T	response regulator	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_64550_1	768710.DesyoDRAFT_0701	3.932e-21	102.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,260UH@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07642,ko:K07652,ko:K10681	ko02020,map02020	M00450,M00459,M00468,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegV,HAMP,HATPase_c,HisKA,Hpt,Response_reg
MMS3_k127_647271_6	479434.Sthe_1992	1.816e-62	220.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi,27XXN@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
MMS3_k127_647271_2	479434.Sthe_1993	2.986e-176	564.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi,27XFZ@189775|Thermomicrobia	189775|Thermomicrobia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
MMS3_k127_647271_3	1382356.JQMP01000004_gene471	5.503e-163	518.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
MMS3_k127_647271_0	479434.Sthe_1996	7.303e-237	746.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi,27Y3G@189775|Thermomicrobia	189775|Thermomicrobia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
MMS3_k127_647271_7	479434.Sthe_1997	2.625e-26	117.0	2DR6K@1|root,33AE2@2|Bacteria,2GBBF@200795|Chloroflexi,27YNM@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FtsL
MMS3_k127_647271_4	479434.Sthe_1998	1.652e-126	412.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
MMS3_k127_647271_5	479434.Sthe_1999	1.578e-67	232.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi,27YAY@189775|Thermomicrobia	189775|Thermomicrobia	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
MMS3_k127_647271_1	479434.Sthe_2003	1.646e-213	674.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
MMS3_k127_650414_3	479434.Sthe_0725	1.742e-43	166.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
MMS3_k127_650414_1	479434.Sthe_1700	1.497e-77	277.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi,27YKC@189775|Thermomicrobia	189775|Thermomicrobia	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
MMS3_k127_650414_2	479434.Sthe_1701	2.208e-45	171.0	COG1555@1|root,COG1555@2|Bacteria,2G9V4@200795|Chloroflexi,27YJ5@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
MMS3_k127_650414_0	1382306.JNIM01000001_gene962	3.989e-245	790.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
MMS3_k127_662137_1	479434.Sthe_2148	3.953e-106	353.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi,27XPC@189775|Thermomicrobia	189775|Thermomicrobia	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
MMS3_k127_662137_3	479434.Sthe_2155	3.555e-38	146.0	COG0718@1|root,COG0718@2|Bacteria,2G77S@200795|Chloroflexi,27YNT@189775|Thermomicrobia	189775|Thermomicrobia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
MMS3_k127_662137_0	1382356.JQMP01000004_gene561	7.418e-115	378.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,27XPZ@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_662137_4	1382356.JQMP01000004_gene559	1.519e-37	151.0	COG2010@1|root,COG2010@2|Bacteria,2G7FH@200795|Chloroflexi,27YII@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
MMS3_k127_662137_2	479434.Sthe_2160	9.712e-68	234.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
MMS3_k127_668113_0	479434.Sthe_0619	3.13e-117	383.0	COG2897@1|root,COG2897@2|Bacteria,2G8NA@200795|Chloroflexi,27Y2I@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMS3_k127_668113_2	935839.JAGJ01000014_gene3558	1.675e-07	57.0	COG1396@1|root,COG1396@2|Bacteria,2IMV0@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
MMS3_k127_668113_1	479434.Sthe_0617	3.719e-44	165.0	COG0432@1|root,COG0432@2|Bacteria,2G9B9@200795|Chloroflexi,27YG9@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
MMS3_k127_668113_3	479434.Sthe_1508	5.189e-07	53.0	COG1485@1|root,COG1485@2|Bacteria	2|Bacteria	S	mitochondrial protein catabolic process	-	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
MMS3_k127_701111_3	316274.Haur_0072	2.182e-13	73.0	2EQIM@1|root,33I4N@2|Bacteria,2G9B7@200795|Chloroflexi,3773Z@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
MMS3_k127_701111_2	765420.OSCT_2044	2.839e-39	161.0	2E0NP@1|root,32W7Q@2|Bacteria,2G9D8@200795|Chloroflexi,375QK@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
MMS3_k127_701111_0	765420.OSCT_1334	1.426e-121	398.0	COG0714@1|root,COG0714@2|Bacteria,2G85W@200795|Chloroflexi,3759A@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
MMS3_k127_701111_1	1521187.JPIM01000009_gene2166	4.412e-44	168.0	COG1721@1|root,COG1721@2|Bacteria,2G7PU@200795|Chloroflexi,375DS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
MMS3_k127_701294_6	398512.JQKC01000027_gene3929	3.165e-10	62.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3WJG0@541000|Ruminococcaceae	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
MMS3_k127_701294_3	479434.Sthe_1578	6.168e-90	307.0	COG1216@1|root,COG1216@2|Bacteria,2G7S5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMS3_k127_701294_0	479434.Sthe_1577	1.423e-200	649.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi,27XP7@189775|Thermomicrobia	189775|Thermomicrobia	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
MMS3_k127_701294_1	479434.Sthe_1576	1.451e-167	536.0	COG5282@1|root,COG5282@2|Bacteria,2G800@200795|Chloroflexi,27XTJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
MMS3_k127_701294_2	479434.Sthe_1574	6.468e-135	441.0	COG1630@1|root,COG1630@2|Bacteria,2G68Z@200795|Chloroflexi,27XN5@189775|Thermomicrobia	189775|Thermomicrobia	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
MMS3_k127_701294_5	1382356.JQMP01000003_gene2593	1.799e-47	183.0	2C7F0@1|root,2Z832@2|Bacteria,2G715@200795|Chloroflexi,27YDA@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM HAS barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_701294_4	479434.Sthe_1572	2.401e-87	294.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi,27XK9@189775|Thermomicrobia	189775|Thermomicrobia	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
MMS3_k127_708243_2	485913.Krac_9178	9.058e-19	88.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	rve
MMS3_k127_708243_0	479434.Sthe_2806	8.896e-172	543.0	COG0346@1|root,COG0346@2|Bacteria,2G7JF@200795|Chloroflexi,27YAW@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_708243_1	479434.Sthe_2805	5.543e-167	527.0	COG2368@1|root,COG2368@2|Bacteria,2GAH7@200795|Chloroflexi,27XER@189775|Thermomicrobia	189775|Thermomicrobia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
MMS3_k127_717277_6	479434.Sthe_1159	2.15e-15	79.0	2A4S5@1|root,30TDK@2|Bacteria,2GA21@200795|Chloroflexi,27YQB@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_717277_4	479434.Sthe_1158	5.055e-105	357.0	COG3307@1|root,COG3307@2|Bacteria,2G79D@200795|Chloroflexi,27Y8C@189775|Thermomicrobia	189775|Thermomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_717277_0	479434.Sthe_1157	3.967e-157	502.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi,27XSM@189775|Thermomicrobia	189775|Thermomicrobia	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMS3_k127_717277_5	1382356.JQMP01000003_gene2570	6.836e-100	344.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi,27XXU@189775|Thermomicrobia	189775|Thermomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
MMS3_k127_717277_2	479434.Sthe_1155	1.152e-131	429.0	COG0392@1|root,COG0392@2|Bacteria,2G6NX@200795|Chloroflexi,27YHP@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMS3_k127_717277_3	479434.Sthe_1154	6.938e-127	416.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,27Y1R@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMS3_k127_717277_1	479434.Sthe_1152	4.769e-157	508.0	COG2244@1|root,COG2244@2|Bacteria,2G6CM@200795|Chloroflexi,27XXP@189775|Thermomicrobia	189775|Thermomicrobia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
MMS3_k127_731405_1	1123508.JH636440_gene2341	1.262e-101	340.0	COG3000@1|root,COG3000@2|Bacteria,2J0YN@203682|Planctomycetes	203682|Planctomycetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
MMS3_k127_731405_0	344747.PM8797T_14911	7.509e-256	794.0	COG4102@1|root,COG4102@2|Bacteria,2IXKR@203682|Planctomycetes	203682|Planctomycetes	T	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
MMS3_k127_731405_4	656024.FsymDg_1250	0.0001846	49.0	COG2337@1|root,COG2337@2|Bacteria,2IQQ9@201174|Actinobacteria	201174|Actinobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005576,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0045927,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
MMS3_k127_731405_3	886293.Sinac_7588	1.045e-16	81.0	COG2010@1|root,COG2010@2|Bacteria,2IYM5@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
MMS3_k127_732927_5	1394178.AWOO02000003_gene2604	7.549e-05	48.0	COG1309@1|root,COG1309@2|Bacteria,2GKW3@201174|Actinobacteria,4EK3I@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMS3_k127_732927_2	1489678.RDMS_07445	8.76e-39	152.0	COG3981@1|root,COG3981@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
MMS3_k127_732927_1	479434.Sthe_0530	2.308e-204	644.0	COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.8	ko:K00255,ko:K11731	ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754,R08089	RC00052,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMS3_k127_732927_3	479434.Sthe_0532	9.271e-39	149.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
MMS3_k127_732927_0	479434.Sthe_0533	3.46e-322	1002.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
MMS3_k127_732927_4	338966.Ppro_1945	4.171e-27	115.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42QRA@68525|delta/epsilon subdivisions,2WN1V@28221|Deltaproteobacteria,43UE5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
MMS3_k127_734013_3	1449126.JQKL01000008_gene224	3.406e-27	113.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,24AJ7@186801|Clostridia	186801|Clostridia	EQ	PFAM Hydantoinase oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
MMS3_k127_734013_0	1089553.Tph_c17120	5.691e-82	286.0	COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,24A65@186801|Clostridia,42FRV@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
MMS3_k127_734013_1	1121948.AUAC01000002_gene1460	1.109e-45	181.0	COG3535@1|root,COG3535@2|Bacteria,1NCBV@1224|Proteobacteria,2TU70@28211|Alphaproteobacteria,43XE6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF917)	-	-	-	-	-	-	-	-	-	-	-	-	DUF917
MMS3_k127_734013_2	2074.JNYD01000047_gene7424	1.565e-39	154.0	COG0778@1|root,COG0778@2|Bacteria,2IEFM@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase family	-	-	1.3.3.13	ko:K21375	-	-	-	-	ko00000,ko01000	-	-	-	Nitroreductase
MMS3_k127_734013_4	342949.PNA2_0474	8.955e-10	64.0	2DZC0@1|root,2N62Z@2157|Archaea,2Y5DH@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_73466_8	479434.Sthe_0422	2.287e-44	162.0	2ETJ3@1|root,33M2W@2|Bacteria,2G7IK@200795|Chloroflexi,27YKN@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_73466_0	479434.Sthe_0425	3.157e-231	721.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,27XS9@189775|Thermomicrobia	189775|Thermomicrobia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
MMS3_k127_73466_3	479434.Sthe_0426	1.845e-106	351.0	COG0689@1|root,COG0689@2|Bacteria,2G69E@200795|Chloroflexi,27Y55@189775|Thermomicrobia	189775|Thermomicrobia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
MMS3_k127_73466_6	479434.Sthe_0433	2.666e-86	289.0	COG0131@1|root,COG0131@2|Bacteria,2G6JA@200795|Chloroflexi,27Y5F@189775|Thermomicrobia	189775|Thermomicrobia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
MMS3_k127_73466_1	479434.Sthe_0434	2.764e-167	532.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi,27XEN@189775|Thermomicrobia	189775|Thermomicrobia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMS3_k127_73466_4	479434.Sthe_0435	1.254e-93	323.0	COG1686@1|root,COG1686@2|Bacteria,2G8TU@200795|Chloroflexi,27Z58@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
MMS3_k127_73466_2	479434.Sthe_0436	9.403e-110	363.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi,27XQ1@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMS3_k127_73466_7	309801.trd_0438	1.888e-70	246.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi,27YEA@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
MMS3_k127_73466_5	479434.Sthe_0438	6.208e-87	294.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi,27Y83@189775|Thermomicrobia	189775|Thermomicrobia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
MMS3_k127_73466_9	767029.HMPREF9154_2625	2.667e-06	54.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4DR3V@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
MMS3_k127_737961_3	298654.FraEuI1c_1438	3.227e-74	265.0	COG3409@1|root,COG3409@2|Bacteria,2I9HW@201174|Actinobacteria	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
MMS3_k127_737961_2	1120950.KB892804_gene1478	8.288e-95	317.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DP5D@85009|Propionibacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_737961_1	298654.FraEuI1c_1436	3.003e-163	525.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4EVR3@85013|Frankiales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMS3_k127_737961_5	1944.JOAZ01000026_gene2614	1.135e-46	175.0	COG0454@1|root,COG0456@2|Bacteria,2II3I@201174|Actinobacteria,41AXR@629295|Streptomyces griseus group	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
MMS3_k127_737961_0	316274.Haur_4673	1.345e-222	712.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi,3752D@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMS3_k127_737961_4	479434.Sthe_2288	3.971e-70	244.0	COG0500@1|root,COG2226@2|Bacteria,2G9GR@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_737961_6	555778.Hneap_0369	2.306e-10	66.0	28UQK@1|root,2ZGUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_744879_3	266117.Rxyl_0545	1.072e-97	326.0	COG3970@1|root,COG3970@2|Bacteria,2GN7V@201174|Actinobacteria	201174|Actinobacteria	S	fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
MMS3_k127_744879_1	479434.Sthe_1858	4.622e-167	536.0	COG0579@1|root,COG0579@2|Bacteria,2G67E@200795|Chloroflexi,27XHD@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD dependent oxidoreductase	-	-	1.1.99.2	ko:K00109	ko00650,map00650	-	R03534	RC00031	ko00000,ko00001,ko01000	-	-	-	DAO
MMS3_k127_744879_4	1382356.JQMP01000003_gene1376	1.535e-81	285.0	COG1363@1|root,COG1363@2|Bacteria,2GB54@200795|Chloroflexi,27YYZ@189775|Thermomicrobia	189775|Thermomicrobia	E	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
MMS3_k127_744879_5	479434.Sthe_3456	3.177e-71	250.0	2A25V@1|root,30QGE@2|Bacteria,2GBEN@200795|Chloroflexi,27Z6F@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_744879_6	797304.Natgr_0441	1.571e-21	102.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XWRG@28890|Euryarchaeota,23VI0@183963|Halobacteria	183963|Halobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMS3_k127_744879_2	1122222.AXWR01000035_gene220	1.579e-136	442.0	COG0205@1|root,COG0205@2|Bacteria,1WM4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
MMS3_k127_744879_0	479434.Sthe_2649	4.444e-258	811.0	COG0465@1|root,COG0465@2|Bacteria,2G63X@200795|Chloroflexi,27XYF@189775|Thermomicrobia	189775|Thermomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMS3_k127_746411_2	479434.Sthe_0390	1.33e-83	281.0	COG1994@1|root,COG1994@2|Bacteria,2G6VM@200795|Chloroflexi,27Y97@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_746411_1	479434.Sthe_0389	1.536e-195	612.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,27XY8@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
MMS3_k127_746411_0	479434.Sthe_0388	2.193e-202	631.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi,27XUE@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
MMS3_k127_746411_3	479434.Sthe_0387	2.609e-57	203.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XGK@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_757245_2	479434.Sthe_1306	1.514e-24	106.0	2BQM8@1|root,32JHB@2|Bacteria,2GA2A@200795|Chloroflexi,27YRG@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_757245_0	357808.RoseRS_0219	1.28e-220	698.0	COG2759@1|root,COG2759@2|Bacteria,2G5QS@200795|Chloroflexi,374WV@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
MMS3_k127_757245_1	479434.Sthe_1304	3.476e-87	296.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi,27YC5@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMS3_k127_757245_3	479434.Sthe_1303	1.687e-23	106.0	COG3404@1|root,COG3404@2|Bacteria,2GA5R@200795|Chloroflexi,27ZC0@189775|Thermomicrobia	189775|Thermomicrobia	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
MMS3_k127_759362_3	1382356.JQMP01000001_gene1212	1.185e-10	69.0	2A4VU@1|root,30THG@2|Bacteria,2GA5F@200795|Chloroflexi,27ZB9@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_759362_1	479434.Sthe_2667	1.266e-52	196.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_759362_0	479434.Sthe_2666	3.956e-127	408.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,27YDQ@189775|Thermomicrobia	189775|Thermomicrobia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_759362_2	479434.Sthe_2665	5.806e-38	151.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
MMS3_k127_766277_0	479434.Sthe_3011	1.086e-236	743.0	COG0405@1|root,COG0405@2|Bacteria,2GABC@200795|Chloroflexi,27XH8@189775|Thermomicrobia	189775|Thermomicrobia	E	TIGRFAM gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_766277_1	555079.Toce_1559	6.174e-106	357.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,42FZM@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Cys Met metabolism	megL	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_766277_2	1128421.JAGA01000002_gene910	2.066e-08	61.0	2DQ8Q@1|root,335AV@2|Bacteria,2NQY5@2323|unclassified Bacteria	2|Bacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
MMS3_k127_766981_5	285535.JOEY01000003_gene10498	1.808e-61	220.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMS3_k127_766981_6	479434.Sthe_3194	1.639e-44	164.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	kdgF	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_766981_4	479434.Sthe_3195	2.145e-73	250.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,TPR_11,TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS
MMS3_k127_766981_0	479434.Sthe_3196	4.322e-161	512.0	COG0180@1|root,COG0180@2|Bacteria,2G5SH@200795|Chloroflexi,27XUX@189775|Thermomicrobia	189775|Thermomicrobia	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
MMS3_k127_766981_2	479434.Sthe_3197	1.985e-82	278.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YAV@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMS3_k127_766981_3	479434.Sthe_3198	7.53e-74	257.0	COG5662@1|root,COG5662@2|Bacteria,2G96Y@200795|Chloroflexi,27YEM@189775|Thermomicrobia	189775|Thermomicrobia	K	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
MMS3_k127_766981_1	118173.KB235910_gene4866	9.865e-127	425.0	COG5001@1|root,COG5001@2|Bacteria,1G2M2@1117|Cyanobacteria,1H7KS@1150|Oscillatoriales	1117|Cyanobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL,GGDEF
MMS3_k127_771062_2	1382356.JQMP01000003_gene1487	2.968e-23	101.0	COG0624@1|root,COG0624@2|Bacteria,2GBDE@200795|Chloroflexi,27YXE@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_771062_1	1382306.JNIM01000001_gene1901	1.511e-103	346.0	COG0672@1|root,COG0672@2|Bacteria,2G6P3@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Iron permease FTR1	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
MMS3_k127_771062_0	479434.Sthe_0262	1.383e-253	789.0	COG0402@1|root,COG0402@2|Bacteria,2G8TD@200795|Chloroflexi,27ZAA@189775|Thermomicrobia	189775|Thermomicrobia	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_777209_10	926560.KE387026_gene4310	1.332e-07	55.0	COG4101@1|root,COG4101@2|Bacteria	2|Bacteria	G	3-hydroxyanthranilate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMS3_k127_777209_6	485913.Krac_3441	2.519e-33	136.0	COG3976@1|root,COG3976@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
MMS3_k127_777209_2	485913.Krac_3440	2.83e-94	316.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE,DUF2271
MMS3_k127_777209_1	485913.Krac_3439	1.615e-181	583.0	COG1018@1|root,COG1018@2|Bacteria,2G9BE@200795|Chloroflexi	2|Bacteria	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1,NQR2_RnfD_RnfE
MMS3_k127_777209_7	1144343.PMI41_00241	1.922e-23	114.0	2CXTU@1|root,32T2K@2|Bacteria,1N5AY@1224|Proteobacteria,2UDIB@28211|Alphaproteobacteria,43HED@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1176)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1176
MMS3_k127_777209_5	479434.Sthe_2405	3.927e-43	174.0	2CXTU@1|root,32BV2@2|Bacteria,2G9TJ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_777209_4	1120950.KB892800_gene1657	2.969e-51	190.0	COG4275@1|root,COG4275@2|Bacteria,2IJYK@201174|Actinobacteria	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_777209_3	1449355.JQNR01000004_gene1668	2.83e-89	301.0	COG4280@1|root,COG4280@2|Bacteria,2GN58@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
MMS3_k127_777209_8	981369.JQMJ01000003_gene7768	9.077e-17	83.0	2DECE@1|root,2ZMCX@2|Bacteria,2GZS5@201174|Actinobacteria,2NJSE@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_777209_0	479434.Sthe_2100	1.467e-188	601.0	COG1376@1|root,COG1376@2|Bacteria,2G8JH@200795|Chloroflexi,27XUR@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMS3_k127_777209_9	479434.Sthe_0666	5.33e-08	54.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	2|Bacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_791588_2	41431.PCC8801_1657	9.208e-17	88.0	COG1309@1|root,COG1309@2|Bacteria,1G56T@1117|Cyanobacteria,3KKTF@43988|Cyanothece	1117|Cyanobacteria	K	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	TniQ
MMS3_k127_791588_1	983917.RGE_17820	7.572e-53	200.0	COG0467@1|root,COG0467@2|Bacteria,1R2RG@1224|Proteobacteria,2VIBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
MMS3_k127_791588_0	1121920.AUAU01000031_gene1406	6.205e-187	617.0	COG2801@1|root,COG2801@2|Bacteria,3Y8JU@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
MMS3_k127_793212_2	1463821.JOGR01000003_gene756	0.0002521	51.0	COG3899@1|root,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
MMS3_k127_793212_1	264731.PRU_0350	3.131e-08	63.0	COG2110@1|root,COG2110@2|Bacteria,4PC88@976|Bacteroidetes,2G043@200643|Bacteroidia	976|Bacteroidetes	S	COG KOG0946 ER-Golgi vesicle-tethering protein p115	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
MMS3_k127_793212_0	1121924.ATWH01000005_gene2556	1.172e-165	533.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4FNC9@85023|Microbacteriaceae	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.1.400	ko:K20927	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
MMS3_k127_800593_1	1117379.BABA_15677	1.457e-140	462.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,1ZDIH@1386|Bacillus	91061|Bacilli	S	amidohydrolase	-	-	-	ko:K12941,ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
MMS3_k127_800593_0	331869.BAL199_02434	4.197e-152	497.0	COG2303@1|root,COG2303@2|Bacteria,1N0NP@1224|Proteobacteria,2TQSK@28211|Alphaproteobacteria,4BRQ5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
MMS3_k127_800593_2	1150398.JIBJ01000003_gene1602	2.219e-06	50.0	COG0580@1|root,COG0580@2|Bacteria,2IG6C@201174|Actinobacteria	201174|Actinobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
MMS3_k127_812192_0	309801.trd_0048	5.617e-107	366.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,2GBGM@200795|Chloroflexi,27YV1@189775|Thermomicrobia	189775|Thermomicrobia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_3
MMS3_k127_812192_1	479434.Sthe_0710	7.191e-09	64.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,2G7UT@200795|Chloroflexi,27Y1B@189775|Thermomicrobia	189775|Thermomicrobia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3
MMS3_k127_813164_0	479434.Sthe_3476	2.889e-162	514.0	COG0022@1|root,COG0022@2|Bacteria,2GAAM@200795|Chloroflexi,27YTG@189775|Thermomicrobia	189775|Thermomicrobia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMS3_k127_813164_2	479434.Sthe_3477	2.652e-145	468.0	COG1071@1|root,COG1071@2|Bacteria,2GAC3@200795|Chloroflexi,27Z5H@189775|Thermomicrobia	189775|Thermomicrobia	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMS3_k127_813164_1	1382356.JQMP01000001_gene1279	2.259e-154	491.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi,27XKQ@189775|Thermomicrobia	189775|Thermomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_820355_12	1380390.JIAT01000013_gene123	1.809e-63	230.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
MMS3_k127_820355_5	383372.Rcas_3701	2.953e-140	482.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
MMS3_k127_820355_2	929556.Solca_1378	9.913e-164	528.0	COG0277@1|root,COG0277@2|Bacteria,4NHFC@976|Bacteroidetes,1IUJ0@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	BBE,DUF805,FAD_binding_4
MMS3_k127_820355_3	867845.KI911784_gene2478	9.173e-155	495.0	COG3938@1|root,COG3938@2|Bacteria,2G5PY@200795|Chloroflexi,376W5@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the proline racemase family	-	-	5.1.1.4,5.1.1.8	ko:K01777,ko:K12658	ko00330,ko01100,map00330,map01100	-	R01255,R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
MMS3_k127_820355_15	485913.Krac_0518	6.107e-42	165.0	COG0491@1|root,COG0491@2|Bacteria,2G9AW@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMS3_k127_820355_18	266117.Rxyl_2945	1.996e-13	74.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
MMS3_k127_820355_1	1128421.JAGA01000001_gene2004	1.965e-282	885.0	COG1523@1|root,COG1523@2|Bacteria,2NPQU@2323|unclassified Bacteria	2|Bacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
MMS3_k127_820355_7	479434.Sthe_1775	6.649e-104	344.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_820355_0	479434.Sthe_1776	0.0	1083.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
MMS3_k127_820355_4	479434.Sthe_3287	8.035e-143	466.0	COG3642@1|root,COG3642@2|Bacteria,2G920@200795|Chloroflexi	200795|Chloroflexi	T	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
MMS3_k127_820355_6	555778.Hneap_0972	2.032e-112	368.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1WXCM@135613|Chromatiales	135613|Chromatiales	S	PFAM Polyphosphate kinase 2	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
MMS3_k127_820355_11	479434.Sthe_2304	7.467e-64	229.0	COG0500@1|root,COG2226@2|Bacteria,2G798@200795|Chloroflexi,27Z7K@189775|Thermomicrobia	189775|Thermomicrobia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_820355_9	565033.GACE_0460	5.628e-91	317.0	COG0477@1|root,arCOG00143@2157|Archaea,2XX8N@28890|Euryarchaeota,246W2@183980|Archaeoglobi	183980|Archaeoglobi	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_820355_14	479434.Sthe_2275	6.456e-50	183.0	COG0847@1|root,COG0847@2|Bacteria,2G74Z@200795|Chloroflexi,27Z7E@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
MMS3_k127_820355_16	1155718.KB891884_gene6012	6.252e-20	91.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria	201174|Actinobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
MMS3_k127_820355_8	1288494.EBAPG3_10890	7.675e-103	345.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2VIGZ@28216|Betaproteobacteria,372V2@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	Mur_ligase_M,PGA_cap
MMS3_k127_820355_17	858215.Thexy_0784	5.149e-17	90.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
MMS3_k127_824378_1	479434.Sthe_3075	9.891e-141	492.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
MMS3_k127_824378_5	1227453.C444_02772	1.468e-40	175.0	arCOG02360@1|root,arCOG02389@1|root,arCOG02360@2157|Archaea,arCOG02389@2157|Archaea,2Y47I@28890|Euryarchaeota,23ZVM@183963|Halobacteria	183963|Halobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,Response_reg
MMS3_k127_824378_8	118166.JH976538_gene5095	2.5e-17	98.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G2QC@1117|Cyanobacteria,1H7Q7@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
MMS3_k127_824378_0	479434.Sthe_2347	8.951e-298	922.0	COG2234@1|root,COG2234@2|Bacteria,2GB74@200795|Chloroflexi,27XKU@189775|Thermomicrobia	189775|Thermomicrobia	S	protease-associated PA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMS3_k127_824378_6	309801.trd_0071	1.342e-27	116.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi,27YE3@189775|Thermomicrobia	189775|Thermomicrobia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
MMS3_k127_824378_3	1121396.KB893105_gene1813	4.331e-101	345.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2MPYF@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_824378_7	525904.Tter_1285	9.116e-18	89.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	yfiV	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
MMS3_k127_824378_2	1121396.KB893105_gene1813	3.691e-103	353.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2MPYF@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_824378_4	479434.Sthe_2206	2.955e-67	238.0	COG1061@1|root,COG1061@2|Bacteria	2|Bacteria	L	Type III restriction enzyme res subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,Helicase_C,RNase_H_2,ResIII
MMS3_k127_826473_5	880072.Desac_2434	1.605e-14	76.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
MMS3_k127_826473_3	479434.Sthe_0599	7.033e-20	95.0	COG2318@1|root,COG2318@2|Bacteria,2G98Y@200795|Chloroflexi,27YQK@189775|Thermomicrobia	189775|Thermomicrobia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
MMS3_k127_826473_4	479434.Sthe_0599	3.031e-18	94.0	COG2318@1|root,COG2318@2|Bacteria,2G98Y@200795|Chloroflexi,27YQK@189775|Thermomicrobia	189775|Thermomicrobia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
MMS3_k127_826473_1	246196.MSMEI_4297	2.027e-43	166.0	COG0546@1|root,COG0546@2|Bacteria,2GJRT@201174|Actinobacteria,23352@1762|Mycobacteriaceae	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
MMS3_k127_826473_0	479434.Sthe_3402	1.308e-158	510.0	COG0624@1|root,COG0624@2|Bacteria,2GBDE@200795|Chloroflexi,27YXE@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_826473_6	1123024.AUII01000015_gene3718	3.551e-14	87.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4ECY0@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
MMS3_k127_826473_2	1370121.AUWS01000007_gene5539	6.258e-41	175.0	COG2114@1|root,COG2909@1|root,COG3629@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3629@2|Bacteria,2GJAR@201174|Actinobacteria,2349V@1762|Mycobacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
MMS3_k127_827366_1	479434.Sthe_1176	4.678e-97	327.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi,27XPA@189775|Thermomicrobia	189775|Thermomicrobia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
MMS3_k127_827366_2	479434.Sthe_1175	2.403e-81	273.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883,ko:K07889,ko:K19144	ko04014,ko04144,ko04145,ko04962,ko05146,ko05152,map04014,map04144,map04145,map04962,map05146,map05152	-	-	-	ko00000,ko00001,ko02048,ko04031,ko04131,ko04147	-	-	-	AAA_24,Cas_csx3,DUF697,MMR_HSR1,Ras
MMS3_k127_827366_0	479434.Sthe_1174	0.0	1137.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi,27Y0P@189775|Thermomicrobia	189775|Thermomicrobia	M	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2
MMS3_k127_834103_3	316274.Haur_1583	2.364e-37	144.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMS3_k127_834103_2	479434.Sthe_3138	4.319e-40	153.0	2E7G3@1|root,331YZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_834103_0	479434.Sthe_2999	1.315e-194	616.0	COG1804@1|root,COG1804@2|Bacteria,2GB4P@200795|Chloroflexi,27XYZ@189775|Thermomicrobia	2|Bacteria	C	L-carnitine dehydratase bile acid-inducible protein F	MA20_43260	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
MMS3_k127_834103_1	479434.Sthe_1791	2.061e-132	426.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi,27YD9@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_840968_1	479434.Sthe_1878	4.391e-252	785.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,27XZ8@189775|Thermomicrobia	189775|Thermomicrobia	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
MMS3_k127_840968_8	479434.Sthe_1877	4.507e-91	303.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi,27Y8S@189775|Thermomicrobia	189775|Thermomicrobia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMS3_k127_840968_5	479434.Sthe_1876	1.352e-140	456.0	COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi,27XT8@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
MMS3_k127_840968_9	479434.Sthe_1875	1.508e-89	302.0	COG0134@1|root,COG0134@2|Bacteria,2G6GG@200795|Chloroflexi,27XGP@189775|Thermomicrobia	189775|Thermomicrobia	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
MMS3_k127_840968_15	479434.Sthe_1874	2.015e-54	200.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi,27YDR@189775|Thermomicrobia	189775|Thermomicrobia	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
MMS3_k127_840968_2	479434.Sthe_1873	4.711e-216	677.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi,27XJP@189775|Thermomicrobia	189775|Thermomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMS3_k127_840968_6	479434.Sthe_1872	1.991e-112	369.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi,27XSP@189775|Thermomicrobia	189775|Thermomicrobia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
MMS3_k127_840968_14	479434.Sthe_1871	3.643e-56	198.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi,27YKI@189775|Thermomicrobia	189775|Thermomicrobia	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
MMS3_k127_840968_3	479434.Sthe_1870	4.415e-164	522.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi,27XKF@189775|Thermomicrobia	189775|Thermomicrobia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
MMS3_k127_840968_11	479434.Sthe_1869	4.536e-85	286.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,2G6YA@200795|Chloroflexi,27Y5D@189775|Thermomicrobia	189775|Thermomicrobia	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
MMS3_k127_840968_13	479434.Sthe_1868	4.946e-59	209.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi,27YEY@189775|Thermomicrobia	189775|Thermomicrobia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
MMS3_k127_840968_17	479434.Sthe_1867	8.028e-22	96.0	COG1837@1|root,COG1837@2|Bacteria,2G9VQ@200795|Chloroflexi,27YME@189775|Thermomicrobia	189775|Thermomicrobia	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
MMS3_k127_840968_16	479434.Sthe_1866	6.332e-37	141.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi,27YHM@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
MMS3_k127_840968_4	269799.Gmet_1148	3.274e-159	514.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,43TPE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMS3_k127_840968_12	479434.Sthe_1864	3.074e-70	246.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi,27YFV@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	-	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
MMS3_k127_840968_0	479434.Sthe_1863	0.0	1017.0	COG1154@1|root,COG1154@2|Bacteria,2G68R@200795|Chloroflexi,27XH0@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
MMS3_k127_840968_7	1382356.JQMP01000004_gene291	3.511e-98	338.0	COG5002@1|root,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,27YXC@189775|Thermomicrobia	189775|Thermomicrobia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMS3_k127_840968_10	1382356.JQMP01000004_gene290	7.769e-88	296.0	COG0745@1|root,COG0745@2|Bacteria,2GBDQ@200795|Chloroflexi,27Z01@189775|Thermomicrobia	189775|Thermomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMS3_k127_848894_19	479434.Sthe_0896	2.763e-19	91.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
MMS3_k127_848894_17	751944.HALDL1_11685	2.798e-26	117.0	COG4315@1|root,arCOG08235@2157|Archaea,2Y0R7@28890|Euryarchaeota,23Y3Z@183963|Halobacteria	183963|Halobacteria	C	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
MMS3_k127_848894_21	1444711.CCJF01000001_gene115	5.349e-11	72.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	ydfB	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
MMS3_k127_848894_5	867903.ThesuDRAFT_01788	2.899e-111	383.0	COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes	1239|Firmicutes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	yjbQ	-	-	ko:K03455,ko:K03499	-	-	-	-	ko00000,ko02000	2.A.37,2.A.38.1,2.A.38.4	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
MMS3_k127_848894_7	1120950.KB892789_gene77	3.805e-106	356.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
MMS3_k127_848894_15	479434.Sthe_2228	3.371e-39	152.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
MMS3_k127_848894_14	479434.Sthe_2734	1.164e-40	158.0	COG5516@1|root,COG5516@2|Bacteria,2G7GV@200795|Chloroflexi	200795|Chloroflexi	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
MMS3_k127_848894_0	479434.Sthe_3121	2.901e-233	730.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi,27XT1@189775|Thermomicrobia	189775|Thermomicrobia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
MMS3_k127_848894_1	479434.Sthe_3109	1.105e-196	627.0	COG0578@1|root,COG0578@2|Bacteria,2G8C0@200795|Chloroflexi,27Y8H@189775|Thermomicrobia	189775|Thermomicrobia	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
MMS3_k127_848894_11	479434.Sthe_3108	1.1e-63	224.0	COG0344@1|root,COG0344@2|Bacteria,2GBUF@200795|Chloroflexi,27ZAT@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
MMS3_k127_848894_9	479434.Sthe_3107	1.754e-99	335.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_848894_12	479434.Sthe_2667	1.109e-62	228.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMS3_k127_848894_6	479434.Sthe_2785	2.931e-106	358.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.8.1.7,4.4.1.16	ko:K03980,ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000,ko01011,ko02000	2.A.66.4	-	-	Peptidase_M28,SLH
MMS3_k127_848894_4	1122223.KB890696_gene471	2.672e-118	390.0	COG2421@1|root,COG2421@2|Bacteria	2|Bacteria	C	formamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
MMS3_k127_848894_3	479434.Sthe_3105	3.969e-187	608.0	COG3935@1|root,COG3935@2|Bacteria,2GB78@200795|Chloroflexi,27XMP@189775|Thermomicrobia	189775|Thermomicrobia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_848894_10	479434.Sthe_3104	1.216e-83	284.0	COG1733@1|root,COG1733@2|Bacteria,2GB8K@200795|Chloroflexi,27Y6Q@189775|Thermomicrobia	189775|Thermomicrobia	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	AAA_assoc_C
MMS3_k127_848894_8	479434.Sthe_3102	1.096e-105	353.0	COG1612@1|root,COG1612@2|Bacteria,2G75U@200795|Chloroflexi,27Y6J@189775|Thermomicrobia	189775|Thermomicrobia	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
MMS3_k127_848894_13	44251.PDUR_18775	1.239e-48	179.0	COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,4HIJ1@91061|Bacilli,275UE@186822|Paenibacillaceae	91061|Bacilli	S	3-demethylubiquinone-9 3-methyltransferase	phnB3	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
MMS3_k127_848894_16	1502724.FF80_01745	7.332e-33	135.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
MMS3_k127_848894_18	1382356.JQMP01000003_gene1537	2.736e-22	102.0	COG1846@1|root,COG1846@2|Bacteria,2G7D6@200795|Chloroflexi,27Z9E@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
MMS3_k127_848894_2	521098.Aaci_1939	5.111e-191	612.0	COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,1TPHW@1239|Firmicutes,4H9YA@91061|Bacilli	91061|Bacilli	P	Major facilitator superfamily	yusP	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
MMS3_k127_848894_20	313625.BL107_10716	1.781e-15	79.0	COG1468@1|root,COG1468@2|Bacteria,1GAY3@1117|Cyanobacteria	1117|Cyanobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
MMS3_k127_852650_0	1121272.KB903290_gene4684	1.088e-46	179.0	2CBE1@1|root,32RT5@2|Bacteria,2IQDS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_852650_2	1101188.KI912155_gene1892	3.296e-42	165.0	COG3629@1|root,COG3629@2|Bacteria,2IBMM@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
MMS3_k127_852650_1	1382306.JNIM01000001_gene1633	2.873e-45	173.0	COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_855598_11	479434.Sthe_2293	3.294e-55	201.0	COG0010@1|root,COG0010@2|Bacteria,2G5N5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
MMS3_k127_855598_0	479434.Sthe_2292	0.0	1081.0	COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi,27XN1@189775|Thermomicrobia	189775|Thermomicrobia	J	DALR anticodon binding domain	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	DALR_1,tRNA-synt_1d
MMS3_k127_855598_5	479434.Sthe_2291	5.218e-138	441.0	COG1209@1|root,COG1209@2|Bacteria,2G6MR@200795|Chloroflexi,27XY3@189775|Thermomicrobia	189775|Thermomicrobia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMS3_k127_855598_13	479434.Sthe_2114	1.273e-46	172.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi,27YHT@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_855598_15	479434.Sthe_2115	3.552e-29	119.0	2B6U1@1|root,31ZTE@2|Bacteria,2GBBT@200795|Chloroflexi,27YPW@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_855598_8	479434.Sthe_2116	1.015e-64	231.0	COG0668@1|root,COG0668@2|Bacteria,2G754@200795|Chloroflexi	200795|Chloroflexi	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
MMS3_k127_855598_16	479434.Sthe_2117	1.278e-23	106.0	COG5513@1|root,COG5513@2|Bacteria,2G9IS@200795|Chloroflexi,27YQC@189775|Thermomicrobia	189775|Thermomicrobia	G	serine-type aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_855598_4	479434.Sthe_2790	5.761e-154	497.0	COG0477@1|root,COG0477@2|Bacteria,2G5YG@200795|Chloroflexi,27XKV@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMS3_k127_855598_2	485913.Krac_4940	5.714e-208	669.0	COG4485@1|root,COG4485@2|Bacteria,2G6VS@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_855598_6	479434.Sthe_2118	5.003e-101	344.0	2ATQQ@1|root,31J9F@2|Bacteria,2GA4K@200795|Chloroflexi,27Z84@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_855598_7	479434.Sthe_2119	6.13e-90	301.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi,27YCK@189775|Thermomicrobia	189775|Thermomicrobia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
MMS3_k127_855598_17	445973.CLOBAR_00896	1.278e-05	53.0	COG1846@1|root,COG1846@2|Bacteria,1V8EW@1239|Firmicutes,24RW7@186801|Clostridia	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
MMS3_k127_855598_3	1051632.TPY_2935	3.56e-200	641.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMS3_k127_855598_1	483219.LILAB_26095	1.825e-308	970.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2YUAS@29|Myxococcales	28221|Deltaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
MMS3_k127_855598_10	404589.Anae109_3831	8.044e-59	216.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,42YGA@68525|delta/epsilon subdivisions,2X9TU@28221|Deltaproteobacteria,2Z21Y@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
MMS3_k127_855598_14	479434.Sthe_3453	5.279e-37	151.0	COG0517@1|root,COG0589@1|root,COG0517@2|Bacteria,COG0589@2|Bacteria,2GBED@200795|Chloroflexi,27Z4M@189775|Thermomicrobia	189775|Thermomicrobia	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Usp
MMS3_k127_855598_12	1382356.JQMP01000003_gene1486	6.132e-55	198.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi	200795|Chloroflexi	F	Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines	pyrR	GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
MMS3_k127_855598_9	1382356.JQMP01000003_gene1487	2.109e-60	215.0	COG0624@1|root,COG0624@2|Bacteria,2GBDE@200795|Chloroflexi,27YXE@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
MMS3_k127_863429_2	479434.Sthe_1501	3.989e-15	75.0	COG1402@1|root,COG1402@2|Bacteria,2G7B0@200795|Chloroflexi,27Y94@189775|Thermomicrobia	189775|Thermomicrobia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_863429_0	479434.Sthe_1500	7.348e-160	512.0	COG0520@1|root,COG0520@2|Bacteria,2G7JU@200795|Chloroflexi,27XQN@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
MMS3_k127_863429_1	1382356.JQMP01000003_gene2462	1.688e-136	441.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi,27Y2Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMS3_k127_882728_2	1445613.JALM01000067_gene5557	9.633e-70	247.0	COG3458@1|root,COG3458@2|Bacteria	2|Bacteria	Q	cephalosporin-C deacetylase activity	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
MMS3_k127_882728_0	1445613.JALM01000067_gene5558	5.117e-94	321.0	COG3458@1|root,COG3458@2|Bacteria,2GNHH@201174|Actinobacteria,4E11A@85010|Pseudonocardiales	201174|Actinobacteria	Q	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
MMS3_k127_882728_1	479434.Sthe_2602	3.936e-72	249.0	COG1670@1|root,COG1670@2|Bacteria,2G8SC@200795|Chloroflexi,27YIG@189775|Thermomicrobia	189775|Thermomicrobia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
MMS3_k127_888745_4	479434.Sthe_1934	5.99e-169	540.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi,27Y12@189775|Thermomicrobia	189775|Thermomicrobia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMS3_k127_888745_7	479434.Sthe_1935	7.37e-150	480.0	COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi,27XY9@189775|Thermomicrobia	189775|Thermomicrobia	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMS3_k127_888745_13	479434.Sthe_1936	9.385e-80	269.0	COG1839@1|root,COG1839@2|Bacteria,2G6BH@200795|Chloroflexi,27Y7D@189775|Thermomicrobia	189775|Thermomicrobia	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
MMS3_k127_888745_2	479434.Sthe_1938	1.599e-187	597.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi,27XIN@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
MMS3_k127_888745_9	479434.Sthe_0854	2.031e-130	434.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Z0M@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
MMS3_k127_888745_0	1382356.JQMP01000003_gene1763	3.739e-237	752.0	COG1807@1|root,COG1807@2|Bacteria,2G6CP@200795|Chloroflexi	200795|Chloroflexi	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMS3_k127_888745_12	234267.Acid_1799	5.059e-105	349.0	COG0384@1|root,COG0384@2|Bacteria,3Y7JN@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
MMS3_k127_888745_3	479434.Sthe_1945	1.053e-174	556.0	COG3288@1|root,COG3288@2|Bacteria,2GB86@200795|Chloroflexi,27XYV@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
MMS3_k127_888745_16	479434.Sthe_1946	6.878e-40	156.0	COG3288@1|root,COG3288@2|Bacteria,2GBAD@200795|Chloroflexi,27YI1@189775|Thermomicrobia	189775|Thermomicrobia	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
MMS3_k127_888745_6	518766.Rmar_2170	5.816e-152	494.0	COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,1FJ60@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
MMS3_k127_888745_10	479434.Sthe_1530	8.034e-124	406.0	COG2141@1|root,COG2141@2|Bacteria,2G99A@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_888745_8	479434.Sthe_1533	5.008e-134	434.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi,27YWI@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMS3_k127_888745_15	479434.Sthe_1534	2.524e-62	215.0	COG0599@1|root,COG0599@2|Bacteria,2GA0S@200795|Chloroflexi,27YG5@189775|Thermomicrobia	189775|Thermomicrobia	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMS3_k127_888745_20	204669.Acid345_1790	5.29e-15	82.0	COG2259@1|root,COG2259@2|Bacteria,3Y5RP@57723|Acidobacteria,2JK0X@204432|Acidobacteriia	204432|Acidobacteriia	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
MMS3_k127_888745_1	479434.Sthe_2367	3.413e-197	618.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,27Y3P@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMS3_k127_888745_11	479434.Sthe_2219	4.658e-115	376.0	COG3294@1|root,COG3294@2|Bacteria,2G6DR@200795|Chloroflexi	200795|Chloroflexi	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
MMS3_k127_888745_5	479434.Sthe_2220	2.245e-153	493.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi,27XZP@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
MMS3_k127_888745_14	1382356.JQMP01000003_gene1999	3.025e-78	266.0	COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi,27Z5R@189775|Thermomicrobia	189775|Thermomicrobia	H	SNO glutamine amidotransferase family	-	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
MMS3_k127_888745_17	1382356.JQMP01000003_gene2000	4.646e-30	119.0	COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi,27XWP@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
MMS3_k127_892116_1	479434.Sthe_1720	1.019e-122	397.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
MMS3_k127_892116_0	479434.Sthe_1721	0.0	1248.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,27Y2U@189775|Thermomicrobia	189775|Thermomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMS3_k127_892116_2	479434.Sthe_1723	2.242e-80	272.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,27Y96@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMS3_k127_892116_3	479434.Sthe_1726	3.057e-73	254.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi,27XK4@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
MMS3_k127_917908_6	479434.Sthe_3242	3.577e-57	203.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
MMS3_k127_917908_3	479434.Sthe_3241	5.602e-103	338.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi,27XVP@189775|Thermomicrobia	189775|Thermomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_917908_5	479434.Sthe_3240	3.125e-84	282.0	COG1522@1|root,COG1522@2|Bacteria,2G77K@200795|Chloroflexi,27YBX@189775|Thermomicrobia	200795|Chloroflexi	K	Transcription regulator	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
MMS3_k127_917908_2	479434.Sthe_3239	9.074e-134	433.0	COG0524@1|root,COG0524@2|Bacteria,2G6QX@200795|Chloroflexi,27XUG@189775|Thermomicrobia	189775|Thermomicrobia	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
MMS3_k127_917908_4	479434.Sthe_3238	7.804e-87	289.0	COG0717@1|root,COG0717@2|Bacteria,2GBA2@200795|Chloroflexi,27Y8U@189775|Thermomicrobia	189775|Thermomicrobia	F	dUTPase	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
MMS3_k127_917908_0	479434.Sthe_3237	2.108e-146	478.0	COG0154@1|root,COG0154@2|Bacteria,2G84N@200795|Chloroflexi,27XQZ@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
MMS3_k127_917908_8	479434.Sthe_3234	2.906e-25	106.0	COG3369@1|root,COG3369@2|Bacteria	2|Bacteria	I	Iron-binding zinc finger CDGSH type	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	zf-CDGSH
MMS3_k127_917908_7	479434.Sthe_3233	5.714e-29	120.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi,27YM0@189775|Thermomicrobia	189775|Thermomicrobia	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
MMS3_k127_917908_1	479434.Sthe_3232	1.725e-140	457.0	COG0446@1|root,COG0446@2|Bacteria,2GA6U@200795|Chloroflexi,27YSM@189775|Thermomicrobia	189775|Thermomicrobia	C	Reductase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
MMS3_k127_923832_9	330084.JNYZ01000008_gene6609	2.522e-27	115.0	COG1142@1|root,COG1142@2|Bacteria,2IQSG@201174|Actinobacteria	201174|Actinobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_923832_3	330084.JNYZ01000008_gene6610	9.515e-93	315.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
MMS3_k127_923832_6	378806.STAUR_8371	2.208e-42	157.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,432IJ@68525|delta/epsilon subdivisions,2WYDE@28221|Deltaproteobacteria,2Z02P@29|Myxococcales	28221|Deltaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMS3_k127_923832_12	1449353.JQMQ01000004_gene6524	2.853e-11	69.0	2BWPS@1|root,345TK@2|Bacteria,2H99A@201174|Actinobacteria,2NMTR@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_923832_7	330084.JNYZ01000029_gene94	5.545e-33	130.0	2BWPS@1|root,345TK@2|Bacteria,2H99A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_923832_5	386456.JQKN01000001_gene1821	1.438e-56	207.0	COG1668@1|root,arCOG01462@2157|Archaea,2Y3YK@28890|Euryarchaeota	28890|Euryarchaeota	C	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_923832_8	235985.BBPN01000009_gene3921	5.844e-28	116.0	2BWPS@1|root,345TK@2|Bacteria,2H99A@201174|Actinobacteria,2NMTR@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_923832_4	386456.JQKN01000001_gene1821	3.11e-61	219.0	COG1668@1|root,arCOG01462@2157|Archaea,2Y3YK@28890|Euryarchaeota	28890|Euryarchaeota	C	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_923832_0	386456.JQKN01000001_gene1822	1.088e-128	418.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT7Q@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMS3_k127_923832_2	1449347.JQLN01000004_gene7144	8.432e-102	339.0	COG0330@1|root,COG0330@2|Bacteria,2GM0Z@201174|Actinobacteria,2M513@2063|Kitasatospora	201174|Actinobacteria	O	prohibitin homologues	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMS3_k127_923832_10	1449353.JQMQ01000005_gene807	8.706e-27	110.0	COG4877@1|root,COG4877@2|Bacteria,2GQV1@201174|Actinobacteria,2NJWV@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_923832_1	525909.Afer_1405	1.431e-114	377.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria	201174|Actinobacteria	P	pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
MMS3_k127_930913_2	479434.Sthe_3368	1.609e-94	331.0	COG3591@1|root,COG3591@2|Bacteria,2G92R@200795|Chloroflexi,27YRZ@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
MMS3_k127_930913_7	794846.AJQU01000036_gene3998	1.14e-18	89.0	COG4274@1|root,COG4274@2|Bacteria,1RKGA@1224|Proteobacteria,2UAJZ@28211|Alphaproteobacteria,4BERT@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_930913_0	479434.Sthe_0722	1.919e-203	657.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2G7EM@200795|Chloroflexi,27Z3D@189775|Thermomicrobia	189775|Thermomicrobia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMS3_k127_930913_5	1121957.ATVL01000008_gene4554	1.453e-19	101.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMS3_k127_930913_6	485913.Krac_0633	9.176e-19	91.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMS3_k127_930913_1	1382356.JQMP01000001_gene970	1.429e-99	332.0	COG3386@1|root,COG3386@2|Bacteria,2GBCX@200795|Chloroflexi,27YTS@189775|Thermomicrobia	189775|Thermomicrobia	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
MMS3_k127_930913_3	911045.PSE_3649	3.484e-65	228.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,2TSRN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	beta-glucosidase	bglA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
MMS3_k127_930913_4	911045.PSE_3649	1.591e-43	162.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,2TSRN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	beta-glucosidase	bglA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
MMS3_k127_944034_0	479434.Sthe_1951	5.493e-212	668.0	COG0191@1|root,COG0191@2|Bacteria,2G689@200795|Chloroflexi	200795|Chloroflexi	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
MMS3_k127_944034_2	1382356.JQMP01000003_gene2449	3.09e-20	94.0	COG4454@1|root,COG4454@2|Bacteria,2GA6H@200795|Chloroflexi,27YMB@189775|Thermomicrobia	189775|Thermomicrobia	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
MMS3_k127_944034_1	479434.Sthe_1950	8.114e-191	606.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_949619_15	864051.BurJ1DRAFT_1560	5.436e-08	64.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,1KJBY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
MMS3_k127_949619_17	1713.JOFV01000014_gene858	1.187e-05	53.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4F2QC@85016|Cellulomonadaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMS3_k127_949619_11	285514.JNWO01000027_gene2245	2.35e-54	198.0	COG2378@1|root,COG2378@2|Bacteria,2H5IT@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
MMS3_k127_949619_4	586413.CCDL010000001_gene1670	6.295e-93	314.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,23JB7@182709|Oceanobacillus	91061|Bacilli	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMS3_k127_949619_3	398511.BpOF4_08035	4.865e-96	323.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,1ZBXY@1386|Bacillus	91061|Bacilli	EP	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMS3_k127_949619_6	324057.Pjdr2_5222	5.101e-76	277.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMS3_k127_949619_2	1382356.JQMP01000003_gene1631	1.782e-118	389.0	COG3608@1|root,COG3608@2|Bacteria	2|Bacteria	G	succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
MMS3_k127_949619_9	1382356.JQMP01000003_gene1632	1.662e-65	232.0	COG1802@1|root,COG1802@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR,HTH_23,HTH_29,HTH_32
MMS3_k127_949619_7	1123023.JIAI01000002_gene5704	3.796e-73	259.0	COG1893@1|root,COG1893@2|Bacteria,2I5ZI@201174|Actinobacteria	201174|Actinobacteria	H	Ketopantoate reductase PanE/ApbA	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMS3_k127_949619_8	1150474.JQJI01000039_gene1925	1.627e-68	249.0	COG1228@1|root,COG1228@2|Bacteria,2GDY6@200918|Thermotogae	200918|Thermotogae	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMS3_k127_949619_12	756883.Halar_2642	8.619e-42	164.0	COG1402@1|root,arCOG04536@2157|Archaea	2157|Archaea	S	Creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
MMS3_k127_949619_0	485913.Krac_6676	6.515e-187	597.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
MMS3_k127_949619_14	1382306.JNIM01000001_gene1380	2.488e-20	97.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMS3_k127_949619_1	479434.Sthe_2515	7.624e-138	442.0	COG3836@1|root,COG3836@2|Bacteria,2G925@200795|Chloroflexi,27YE5@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
MMS3_k127_949619_10	485913.Krac_4810	2.264e-62	224.0	COG2141@1|root,COG2141@2|Bacteria,2G8NG@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_949619_5	1123393.KB891326_gene72	1.33e-82	286.0	COG2187@1|root,COG2187@2|Bacteria,1R98V@1224|Proteobacteria,2VM22@28216|Betaproteobacteria,1KSS9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_949619_13	472759.Nhal_2962	6.128e-27	113.0	COG0462@1|root,COG0462@2|Bacteria,1QHJ7@1224|Proteobacteria,1RZJH@1236|Gammaproteobacteria,1WZXT@135613|Chromatiales	135613|Chromatiales	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
MMS3_k127_964639_0	1173027.Mic7113_4471	1.1e-69	244.0	arCOG12117@1|root,2Z9N1@2|Bacteria,1G2YP@1117|Cyanobacteria,1HE2N@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF3891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3891
MMS3_k127_964639_1	649831.L083_3229	4.827e-25	108.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DH0I@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
MMS3_k127_977027_2	479434.Sthe_1839	2.215e-113	372.0	COG0777@1|root,COG0777@2|Bacteria,2G6E1@200795|Chloroflexi,27XIF@189775|Thermomicrobia	189775|Thermomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	-	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMS3_k127_977027_1	479434.Sthe_1840	7.682e-122	396.0	COG0825@1|root,COG0825@2|Bacteria,2G7S3@200795|Chloroflexi,27XK7@189775|Thermomicrobia	189775|Thermomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	-	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
MMS3_k127_977027_0	479434.Sthe_1844	1.916e-132	430.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G719@200795|Chloroflexi,27XT5@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
MMS3_k127_979551_15	192952.MM_1468	1.04e-13	76.0	arCOG06838@1|root,arCOG06838@2157|Archaea,2Y4P8@28890|Euryarchaeota,2NB41@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_979551_12	1206733.BAGC01000040_gene1564	3.115e-39	151.0	COG3467@1|root,COG3467@2|Bacteria,2IKUR@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
MMS3_k127_979551_5	251229.Chro_2593	3.51e-111	367.0	COG1131@1|root,COG1131@2|Bacteria,1GDU7@1117|Cyanobacteria	1117|Cyanobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMS3_k127_979551_11	251229.Chro_5101	1.644e-42	164.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
MMS3_k127_979551_7	1128421.JAGA01000001_gene2029	1.237e-75	268.0	COG0665@1|root,COG0665@2|Bacteria,2NRT0@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	puuB	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
MMS3_k127_979551_9	1382356.JQMP01000003_gene1798	1.035e-54	205.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi,27YD9@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMS3_k127_979551_0	479434.Sthe_2516	3.182e-298	927.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_979551_1	479434.Sthe_2516	9.806e-262	822.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_979551_13	479434.Sthe_2516	4.451e-37	143.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_979551_2	479434.Sthe_2516	8.467e-211	666.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
MMS3_k127_979551_10	926550.CLDAP_09500	1.46e-50	184.0	COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
MMS3_k127_979551_8	331869.BAL199_24289	1.227e-67	236.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VC8M@28211|Alphaproteobacteria,4BSKF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_979551_6	1382356.JQMP01000003_gene1864	4.852e-108	360.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding
MMS3_k127_979551_4	760568.Desku_1349	8.859e-128	420.0	COG0045@1|root,COG0045@2|Bacteria,1UYAU@1239|Firmicutes,24FES@186801|Clostridia,264FC@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the succinate malate CoA ligase beta subunit family	-	-	6.2.1.18,6.2.1.5	ko:K01903,ko:K15232	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R01322,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Citrate_bind
MMS3_k127_979551_16	452652.KSE_67890	2.923e-13	78.0	COG0645@1|root,COG0645@2|Bacteria,2II7C@201174|Actinobacteria,2M5AJ@2063|Kitasatospora	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
MMS3_k127_979551_3	479434.Sthe_1789	9.117e-182	582.0	COG2079@1|root,COG2079@2|Bacteria,2G7JZ@200795|Chloroflexi,27Z14@189775|Thermomicrobia	189775|Thermomicrobia	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
MMS3_k127_979551_14	1382356.JQMP01000003_gene1861	2.582e-15	82.0	2ADNP@1|root,313DJ@2|Bacteria,2GA58@200795|Chloroflexi,27ZAI@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMS3_k127_979551_17	479434.Sthe_1785	5.971e-10	63.0	2A8ME@1|root,30XPV@2|Bacteria,2GA0N@200795|Chloroflexi,27YFF@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 3763 queries scanned
## Total time (seconds): 125.57811880111694
## Rate: 29.97 q/s