## Wed Nov 13 00:18:46 2024 ## emapper-2.1.12 ## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/P/PJD2_bin.18.fa -m mmseqs --itype genome -o PJD2_bin.18 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/PJD2_bin.18 --cpu 28 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs PJD2_k127_1006492_7 1248917.ANFX01000008_gene307 8.32e-36 138.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U5RA@28211|Alphaproteobacteria,2JZWN@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09973 - - - - ko00000 - - - TraB PJD2_k127_1006492_5 1219035.NT2_06_00500 2.907e-74 264.0 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U3RF@28211|Alphaproteobacteria,2K4KP@204457|Sphingomonadales 204457|Sphingomonadales S TraB family - - - ko:K09973 - - - - ko00000 - - - TraB PJD2_k127_1006492_3 291985.CCSI01000001_gene2267 5.209e-99 328.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,2K122@204457|Sphingomonadales 204457|Sphingomonadales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C PJD2_k127_1006492_1 1090320.KB900605_gene3312 1.941e-107 349.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,2K0UK@204457|Sphingomonadales 204457|Sphingomonadales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro PJD2_k127_1006492_2 1396418.BATQ01000133_gene4091 2.909e-107 360.0 COG2239@1|root,COG2239@2|Bacteria,46S6D@74201|Verrucomicrobia,2IU82@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Divalent cation transporter - - - - - - - - - - - - CBS,MgtE,MgtE_N PJD2_k127_1006492_0 1479239.JQMU01000001_gene2664 6.985e-201 629.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,2K213@204457|Sphingomonadales 204457|Sphingomonadales J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C PJD2_k127_1006492_4 291985.CCSI01000001_gene2260 4.429e-91 308.0 2DBB1@1|root,2Z854@2|Bacteria,1RJKG@1224|Proteobacteria,2U3G4@28211|Alphaproteobacteria,2K4WB@204457|Sphingomonadales 204457|Sphingomonadales S Domain of Unknown Function (DUF1206) - - - - - - - - - - - - DUF1206 PJD2_k127_1006492_6 279238.Saro_2122 8.097e-47 174.0 COG0789@1|root,COG0789@2|Bacteria,1N0AZ@1224|Proteobacteria,2UD14@28211|Alphaproteobacteria,2KD6Z@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn_helix, mercury resistance - - - ko:K08365 - - - - ko00000,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 PJD2_k127_1006492_8 1331060.RLDS_08470 3.261e-16 79.0 COG0695@1|root,COG0695@2|Bacteria,1MXQW@1224|Proteobacteria,2TT7R@28211|Alphaproteobacteria,2K12W@204457|Sphingomonadales 204457|Sphingomonadales O COG0695 glutaredoxin and related proteins - - - - - - - - - - - - Glutaredoxin,MauE PJD2_k127_1006680_0 1219035.NT2_12_00650 5.567e-139 445.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2K0V3@204457|Sphingomonadales 204457|Sphingomonadales S N-carbamoylputrescine amidase aguB - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase PJD2_k127_1006680_1 279238.Saro_3094 7.675e-122 402.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,2U5HN@28211|Alphaproteobacteria,2K2C2@204457|Sphingomonadales 204457|Sphingomonadales S Methyltransferase - - - - - - - - - - - - Methyltransf_11 PJD2_k127_1006680_2 158500.BV97_01061 2.542e-97 320.0 COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,2K0CZ@204457|Sphingomonadales 204457|Sphingomonadales O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR PJD2_k127_1006680_3 1502850.FG91_04080 2.54e-79 266.0 COG2885@1|root,COG2885@2|Bacteria,1R5IS@1224|Proteobacteria,2U2V8@28211|Alphaproteobacteria,2K1H8@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the ompA family - - - - - - - - - - - - OmpA PJD2_k127_1022763_3 1219035.NT2_04_01890 5.283e-16 77.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,2K0R5@204457|Sphingomonadales 204457|Sphingomonadales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS PJD2_k127_1022763_0 1545915.JROG01000008_gene3372 5.778e-221 697.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2JZXX@204457|Sphingomonadales 204457|Sphingomonadales Q Oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 PJD2_k127_1022763_1 1122970.AUHC01000011_gene2773 6.212e-88 299.0 COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2TTDD@28211|Alphaproteobacteria,2K3XP@204457|Sphingomonadales 204457|Sphingomonadales O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA_1 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR PJD2_k127_1022763_2 383381.EH30_14385 9.854e-64 232.0 COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,2UJ22@28211|Alphaproteobacteria,2KD76@204457|Sphingomonadales 204457|Sphingomonadales P Belongs to the Fur family - - - ko:K09823 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - FUR PJD2_k127_1022763_4 1088721.NSU_1890 3.951e-13 71.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,2K0XY@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C PJD2_k127_1070480_4 1219035.NT2_05_02750 9.596e-82 276.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,2K0IX@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b PJD2_k127_1070480_0 314225.ELI_00615 1.985e-197 623.0 COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria,2UF0X@28211|Alphaproteobacteria,2KEJ5@204457|Sphingomonadales 204457|Sphingomonadales S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 PJD2_k127_1070480_6 392499.Swit_0266 7.949e-62 222.0 COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,2K4W9@204457|Sphingomonadales 204457|Sphingomonadales T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp PJD2_k127_1070480_3 1123269.NX02_09290 5.524e-85 289.0 COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2U6QG@28211|Alphaproteobacteria,2K4AR@204457|Sphingomonadales 204457|Sphingomonadales S bacterial OsmY and nodulation domain - - - - - - - - - - - - BON PJD2_k127_1070480_10 13689.BV96_04274 3.728e-23 104.0 COG4566@1|root,COG4566@2|Bacteria,1NQFJ@1224|Proteobacteria,2UP0T@28211|Alphaproteobacteria,2K5UQ@204457|Sphingomonadales 204457|Sphingomonadales T Response regulator receiver domain - - - - - - - - - - - - Response_reg PJD2_k127_1070480_1 366602.Caul_2969 2.44e-178 578.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2KJYY@204458|Caulobacterales 204458|Caulobacterales T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS PJD2_k127_1070480_5 279238.Saro_1616 3.141e-76 282.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2UQRR@28211|Alphaproteobacteria,2KDU7@204457|Sphingomonadales 204457|Sphingomonadales K Bacterial regulatory proteins, luxR family - - - ko:K14987 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg PJD2_k127_1070480_7 288000.BBta_0645 4.515e-52 192.0 COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2U8N1@28211|Alphaproteobacteria,3JY5Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX PJD2_k127_1070480_2 1449076.JOOE01000001_gene2203 2.001e-104 353.0 COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2U0C9@28211|Alphaproteobacteria,2K374@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC PJD2_k127_1070480_8 627192.SLG_38200 1.135e-43 171.0 COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,2K4W9@204457|Sphingomonadales 204457|Sphingomonadales T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp PJD2_k127_1070480_9 13689.BV96_00311 4.334e-31 130.0 COG2249@1|root,COG2249@2|Bacteria,1MUHN@1224|Proteobacteria,2U9KV@28211|Alphaproteobacteria,2K5DM@204457|Sphingomonadales 204457|Sphingomonadales S Flavodoxin-like fold - - - - - - - - - - - - Flavodoxin_2 PJD2_k127_1088669_3 702113.PP1Y_AT20635 9.185e-39 148.0 COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,2U0S5@28211|Alphaproteobacteria,2K0JT@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_1088669_4 314225.ELI_02445 1.118e-31 133.0 COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,2K5YV@204457|Sphingomonadales 204457|Sphingomonadales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - PurS PJD2_k127_1088669_1 702113.PP1Y_AT20553 2.102e-117 381.0 COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria,2K0NC@204457|Sphingomonadales 204457|Sphingomonadales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 PJD2_k127_1088669_0 279238.Saro_1031 6.234e-303 947.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales 204457|Sphingomonadales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_4 PJD2_k127_1088669_2 1096930.L284_20655 8.707e-47 168.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,2K017@204457|Sphingomonadales 204457|Sphingomonadales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS PJD2_k127_1096077_1 161528.ED21_26068 5.641e-62 214.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,2K0R3@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase PJD2_k127_1096077_0 1123269.NX02_25515 9.559e-117 386.0 COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,2TRTX@28211|Alphaproteobacteria,2K1FI@204457|Sphingomonadales 204457|Sphingomonadales Q Chalcone and stilbene synthases, C-terminal domain - - - - - - - - - - - - Chal_sti_synt_C,Chal_sti_synt_N PJD2_k127_1096077_2 1112212.JH584235_gene2524 2.575e-58 207.0 COG0500@1|root,COG0500@2|Bacteria,1RESN@1224|Proteobacteria,2U9WF@28211|Alphaproteobacteria,2K139@204457|Sphingomonadales 204457|Sphingomonadales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 PJD2_k127_1102865_1 291985.CCSI01000004_gene606 1.254e-265 831.0 COG4206@1|root,COG4206@2|Bacteria,1R1WX@1224|Proteobacteria,2U0GK@28211|Alphaproteobacteria,2K1DC@204457|Sphingomonadales 204457|Sphingomonadales H receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec PJD2_k127_1102865_4 161528.ED21_23571 1.671e-104 344.0 COG1218@1|root,COG1218@2|Bacteria,1MY0Z@1224|Proteobacteria,2TQWF@28211|Alphaproteobacteria,2K0NZ@204457|Sphingomonadales 204457|Sphingomonadales P 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase - - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P PJD2_k127_1102865_0 1545915.JROG01000004_gene2255 0.0 1078.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,2K22T@204457|Sphingomonadales 204457|Sphingomonadales P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysC - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D2 PJD2_k127_1102865_2 983920.Y88_1191 3.885e-176 559.0 COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2TT2D@28211|Alphaproteobacteria,2K1HF@204457|Sphingomonadales 204457|Sphingomonadales EH sulfate adenylyltransferase cysD - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct PJD2_k127_1102865_3 13689.BV96_04645 2.575e-140 453.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2TSQ2@28211|Alphaproteobacteria,2K1GY@204457|Sphingomonadales 204457|Sphingomonadales P NnrS protein - - - - - - - - - - - - NnrS PJD2_k127_1160814_1 1219035.NT2_02_05210 2.159e-120 391.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria,2K1Y8@204457|Sphingomonadales 204457|Sphingomonadales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase PJD2_k127_1160814_0 1449076.JOOE01000003_gene3239 4.578e-191 610.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria,2K02E@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N PJD2_k127_1290175_9 1219035.NT2_04_04280 1.406e-77 263.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2TTXU@28211|Alphaproteobacteria,2K13X@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 PJD2_k127_1290175_5 161528.ED21_19937 6.514e-100 329.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2TTT2@28211|Alphaproteobacteria,2K1YX@204457|Sphingomonadales 204457|Sphingomonadales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N PJD2_k127_1290175_0 1219035.NT2_04_04300 3.568e-258 802.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,2K0CE@204457|Sphingomonadales 204457|Sphingomonadales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B PJD2_k127_1290175_3 1219035.NT2_04_04310 1.597e-128 416.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,2K07X@204457|Sphingomonadales 204457|Sphingomonadales C Cytochrome c1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 PJD2_k127_1290175_8 983920.Y88_2313 6.175e-79 269.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2TV7J@28211|Alphaproteobacteria,2K25N@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran PJD2_k127_1290175_10 1280952.HJA_02185 1.337e-61 229.0 COG5485@1|root,COG5485@2|Bacteria,1RFES@1224|Proteobacteria,2U8B5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL_2 PJD2_k127_1290175_4 314225.ELI_13700 1.828e-123 402.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,2K0S2@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase PJD2_k127_1290175_2 314225.ELI_13705 1.253e-131 424.0 COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria,2K06A@204457|Sphingomonadales 204457|Sphingomonadales D involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - MipZ PJD2_k127_1290175_11 383381.EH30_15855 6.039e-28 117.0 COG2214@1|root,COG2214@2|Bacteria,1Q605@1224|Proteobacteria,2VC9B@28211|Alphaproteobacteria,2K87K@204457|Sphingomonadales 204457|Sphingomonadales O molecular chaperone - - - - - - - - - - - - DnaJ PJD2_k127_1290175_1 1219035.NT2_04_04380 4.436e-248 771.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,2K0Q1@204457|Sphingomonadales 204457|Sphingomonadales G phosphomannomutase - - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV PJD2_k127_1290175_6 460265.Mnod_1827 3.281e-81 282.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,2TVQN@28211|Alphaproteobacteria,1JRH0@119045|Methylobacteriaceae 28211|Alphaproteobacteria P PFAM Cation efflux - - - - - - - - - - - - Cation_efflux PJD2_k127_1290175_7 314225.ELI_13725 2.551e-79 276.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,2K0I6@204457|Sphingomonadales 204457|Sphingomonadales L helicase lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C PJD2_k127_1293789_1 1123267.JONN01000001_gene1181 2.249e-143 477.0 COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2TRZX@28211|Alphaproteobacteria,2K20R@204457|Sphingomonadales 204457|Sphingomonadales CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 PJD2_k127_1293789_0 314225.ELI_07710 3.321e-211 665.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2K061@204457|Sphingomonadales 204457|Sphingomonadales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N PJD2_k127_1315394_0 685035.ADAE01000018_gene1144 1.509e-150 479.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TSA0@28211|Alphaproteobacteria,2K081@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N PJD2_k127_1315394_1 279238.Saro_1070 1.875e-138 443.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2TRPN@28211|Alphaproteobacteria,2K13W@204457|Sphingomonadales 204457|Sphingomonadales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short,adh_short_C2 PJD2_k127_1315394_2 161528.ED21_31029 3.507e-112 369.0 COG1024@1|root,COG1024@2|Bacteria,1MVPQ@1224|Proteobacteria,2TTJ4@28211|Alphaproteobacteria,2K20K@204457|Sphingomonadales 204457|Sphingomonadales I enoyl-CoA hydratase - - - - - - - - - - - - ECH_1 PJD2_k127_1317322_3 314225.ELI_03625 9.478e-92 303.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,2K0QQ@204457|Sphingomonadales 204457|Sphingomonadales S of ABC transporters with duplicated ATPase - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD PJD2_k127_1317322_4 1219035.NT2_01_03840 2.036e-80 274.0 COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,2K40S@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF541) - - - ko:K09807 - - - - ko00000 - - - SIMPL PJD2_k127_1317322_6 1479239.JQMU01000001_gene509 1.196e-26 113.0 29288@1|root,2ZPSV@2|Bacteria,1NJAG@1224|Proteobacteria,2UMCR@28211|Alphaproteobacteria,2K6S1@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - PepSY PJD2_k127_1317322_2 161528.ED21_25166 1.892e-137 439.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2TSV8@28211|Alphaproteobacteria,2K0M9@204457|Sphingomonadales 204457|Sphingomonadales T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C PJD2_k127_1317322_0 314225.ELI_03650 1.415e-223 703.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,2TS9N@28211|Alphaproteobacteria,2K1P6@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - 2CSK_N,HATPase_c PJD2_k127_1317322_5 1122970.AUHC01000009_gene302 9.229e-43 159.0 COG1605@1|root,COG1605@2|Bacteria,1MZTQ@1224|Proteobacteria,2UCMC@28211|Alphaproteobacteria,2K610@204457|Sphingomonadales 204457|Sphingomonadales E chorismate mutase - - 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 PJD2_k127_1317322_1 685035.ADAE01000020_gene1482 6.575e-166 529.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,2JZY9@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt PJD2_k127_1317322_7 1335760.ASTG01000005_gene1137 9.992e-08 56.0 COG3637@1|root,COG3637@2|Bacteria,1NJWW@1224|Proteobacteria,2UD8G@28211|Alphaproteobacteria,2K4HB@204457|Sphingomonadales 204457|Sphingomonadales M Outer membrane protein beta-barrel domain - - - ko:K16079 - - - - ko00000,ko02000 1.B.4.2.1 - - OMP_b-brl PJD2_k127_1333228_1 1000565.METUNv1_01234 5.703e-87 293.0 COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2VNEC@28216|Betaproteobacteria,2KVSG@206389|Rhodocyclales 206389|Rhodocyclales P Binding-protein-dependent transport system inner membrane component - - - ko:K05773 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - BPD_transp_1 PJD2_k127_1333228_2 1123072.AUDH01000033_gene1982 2.385e-76 276.0 COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2TSCU@28211|Alphaproteobacteria,2JRVW@204441|Rhodospirillales 204441|Rhodospirillales E ABC transporter - - - - - - - - - - - - ABC_tran PJD2_k127_1333228_0 1000565.METUNv1_01232 1.629e-124 416.0 COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2VJQG@28216|Betaproteobacteria,2KUXA@206389|Rhodocyclales 206389|Rhodocyclales H Bacterial extracellular solute-binding protein - - - ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - PBP_like_2 PJD2_k127_1333228_3 1173020.Cha6605_4325 2.246e-67 239.0 COG0730@1|root,COG0730@2|Bacteria,1G72I@1117|Cyanobacteria 1117|Cyanobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE PJD2_k127_1333228_4 1415779.JOMH01000001_gene309 1.576e-34 145.0 COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,1SDB7@1236|Gammaproteobacteria,1X7ZI@135614|Xanthomonadales 135614|Xanthomonadales S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD PJD2_k127_1391842_4 1112214.AHIS01000025_gene1249 1.26e-38 147.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,2K1CI@204457|Sphingomonadales 204457|Sphingomonadales S membrane - - - - - - - - - - - - VIT1 PJD2_k127_1391842_0 1120705.FG95_02956 8.716e-280 878.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K02W@204457|Sphingomonadales 204457|Sphingomonadales O peptidase M13 - - - - - - - - - - - - Peptidase_M13,Peptidase_M13_N PJD2_k127_1391842_1 158500.BV97_05725 6.221e-97 325.0 COG3403@1|root,COG3403@2|Bacteria,1RB0K@1224|Proteobacteria,2U584@28211|Alphaproteobacteria,2K1AD@204457|Sphingomonadales 204457|Sphingomonadales S YqcI/YcgG family - - - ko:K09190 - - - - ko00000 - - - YqcI_YcgG PJD2_k127_1391842_2 517722.AEUE01000003_gene1442 7.451e-93 310.0 COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2TSFM@28211|Alphaproteobacteria,2K0VD@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 PJD2_k127_1391842_3 517722.AEUE01000003_gene1590 3.546e-56 202.0 COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,2K3F8@204457|Sphingomonadales 204457|Sphingomonadales J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase PJD2_k127_1404989_3 685035.ADAE01000018_gene565 3.085e-174 552.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2K03C@204457|Sphingomonadales 204457|Sphingomonadales E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 PJD2_k127_1404989_7 279238.Saro_2041 9.987e-66 246.0 COG3871@1|root,COG3871@2|Bacteria,1RGK0@1224|Proteobacteria,2VFX3@28211|Alphaproteobacteria,2K4WD@204457|Sphingomonadales 204457|Sphingomonadales S Pyridoxamine 5'-phosphate oxidase like - - - - - - - - - - - - Pyrid_ox_like PJD2_k127_1404989_5 314225.ELI_05365 8.234e-85 288.0 COG4544@1|root,COG4544@2|Bacteria,1MY56@1224|Proteobacteria,2U9Y7@28211|Alphaproteobacteria,2K4KW@204457|Sphingomonadales 204457|Sphingomonadales S SOS response - - - ko:K14160 - - - - ko00000,ko03400 - - - - PJD2_k127_1404989_1 314225.ELI_05370 1.589e-257 806.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,2JZYV@204457|Sphingomonadales 204457|Sphingomonadales L Nucleotidyltransferase DNA polymerase involved in DNA repair - - - ko:K14161 - - - - ko00000,ko03400 - - - IMS PJD2_k127_1404989_8 702113.PP1Y_AT33420 2.309e-11 72.0 29W4J@1|root,30HPF@2|Bacteria,1P4I4@1224|Proteobacteria,2UXIS@28211|Alphaproteobacteria,2KBXW@204457|Sphingomonadales 204457|Sphingomonadales S PilZ domain - - - - - - - - - - - - PilZ PJD2_k127_1404989_6 1114964.L485_13920 2.063e-84 287.0 COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,2U5WZ@28211|Alphaproteobacteria,2K4K1@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 PJD2_k127_1404989_2 161528.ED21_29053 2.339e-242 755.0 COG4277@1|root,COG4277@2|Bacteria,1MVCV@1224|Proteobacteria,2TT5U@28211|Alphaproteobacteria,2K0AV@204457|Sphingomonadales 204457|Sphingomonadales S DNA-binding protein with the helix-hairpin-helix motif - - - - - - - - - - - - - PJD2_k127_1404989_0 291985.CCSI01000001_gene2662 3.942e-259 805.0 COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,2K0Y7@204457|Sphingomonadales 204457|Sphingomonadales L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG PJD2_k127_1404989_4 383381.EH30_05310 5.768e-125 405.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,2JZWI@204457|Sphingomonadales 204457|Sphingomonadales L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon PJD2_k127_1437408_8 383381.EH30_03700 3.97e-06 49.0 2BSNS@1|root,32MRD@2|Bacteria,1PA9T@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - PJD2_k127_1437408_7 1088721.NSU_2919 4.64e-14 76.0 COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria,2UJAV@28211|Alphaproteobacteria,2K84T@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the UPF0337 (CsbD) family - - - - - - - - - - - - CsbD PJD2_k127_1437408_6 1096930.L284_19340 8.066e-64 220.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria,2K5EU@204457|Sphingomonadales 204457|Sphingomonadales S EVE domain - - - - - - - - - - - - EVE PJD2_k127_1437408_0 314225.ELI_03920 5.413e-215 681.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2U05U@28211|Alphaproteobacteria,2K1IQ@204457|Sphingomonadales 204457|Sphingomonadales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF PJD2_k127_1437408_4 314225.ELI_03915 2.586e-120 391.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,2K1PV@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase PJD2_k127_1437408_1 1219035.NT2_01_03230 5.086e-174 561.0 COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,2K0WZ@204457|Sphingomonadales 204457|Sphingomonadales J 2-methylthioadenine - - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 PJD2_k127_1437408_3 291985.CCSI01000001_gene1949 4.988e-162 515.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,2K03J@204457|Sphingomonadales 204457|Sphingomonadales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N PJD2_k127_1437408_5 1479239.JQMU01000001_gene461 1.581e-75 273.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2U74X@28211|Alphaproteobacteria,2K4N8@204457|Sphingomonadales 204457|Sphingomonadales D probably involved in intracellular septation ispZ - - ko:K06190 - - - - ko00000 - - - IspA PJD2_k127_1437408_2 161528.ED21_25442 3.256e-170 539.0 COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2TRVJ@28211|Alphaproteobacteria,2JZUZ@204457|Sphingomonadales 204457|Sphingomonadales P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans PJD2_k127_1442029_6 702113.PP1Y_AT17229 0.0001172 44.0 COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2U78G@28211|Alphaproteobacteria,2K4FM@204457|Sphingomonadales 204457|Sphingomonadales S dioxygenase of extradiol dioxygenase family - - - ko:K06991 - - - - ko00000 - - - Glyoxalase PJD2_k127_1442029_5 1234595.C725_1844 2.473e-68 243.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,4BQG6@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_2,GST_N_3 PJD2_k127_1442029_2 161528.ED21_22778 2.281e-116 392.0 28JIP@1|root,2Z82C@2|Bacteria,1R380@1224|Proteobacteria,2TZZ4@28211|Alphaproteobacteria,2KEWB@204457|Sphingomonadales 204457|Sphingomonadales S S1/P1 Nuclease - - - - - - - - - - - - S1-P1_nuclease PJD2_k127_1442029_4 685035.ADAE01000007_gene1383 1.11e-75 258.0 COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,2U7QQ@28211|Alphaproteobacteria,2K4VJ@204457|Sphingomonadales 204457|Sphingomonadales S Cupin domain - - - - - - - - - - - - Cupin_2 PJD2_k127_1442029_1 158500.BV97_02656 9.681e-181 574.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2TT0J@28211|Alphaproteobacteria,2K0C3@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 PJD2_k127_1442029_0 1120705.FG95_02684 9.734e-196 619.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TUFB@28211|Alphaproteobacteria,2K0FM@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF PJD2_k127_1442029_3 1479239.JQMU01000001_gene1688 2.735e-112 365.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2TRI2@28211|Alphaproteobacteria,2K0EP@204457|Sphingomonadales 204457|Sphingomonadales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD PJD2_k127_1472406_0 46429.BV95_04132 0.0 1385.0 COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,2U4DF@28211|Alphaproteobacteria,2K18I@204457|Sphingomonadales 204457|Sphingomonadales S LVIVD repeat - - - - - - - - - - - - LVIVD PJD2_k127_1500248_2 291985.CCSI01000004_gene819 5.198e-144 467.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,2K10E@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C PJD2_k127_1500248_4 685035.ADAE01000018_gene932 5.348e-103 342.0 COG0625@1|root,COG0625@2|Bacteria,1N8XH@1224|Proteobacteria,2TTHQ@28211|Alphaproteobacteria,2K1AK@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_3 PJD2_k127_1500248_8 1219035.NT2_02_02540 4.226e-36 148.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2UF6U@28211|Alphaproteobacteria,2K60E@204457|Sphingomonadales 204457|Sphingomonadales T Belongs to the BolA IbaG family - - - ko:K05527 - - - - ko00000,ko03000 - - - BolA PJD2_k127_1500248_5 1248917.ANFX01000037_gene2030 2.681e-70 250.0 COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria,2K4VC@204457|Sphingomonadales 204457|Sphingomonadales O molecular chaperone - - - - - - - - - - - - DnaJ PJD2_k127_1500248_1 314225.ELI_01620 4.05e-249 781.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2K1UV@204457|Sphingomonadales 204457|Sphingomonadales S Metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_3 PJD2_k127_1500248_6 1479239.JQMU01000001_gene2475 1.092e-58 209.0 COG2050@1|root,COG2050@2|Bacteria,1RHK6@1224|Proteobacteria,2U72Z@28211|Alphaproteobacteria,2K530@204457|Sphingomonadales 204457|Sphingomonadales Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT PJD2_k127_1500248_7 1122970.AUHC01000005_gene1879 2.597e-44 165.0 COG2050@1|root,COG2050@2|Bacteria,1RITB@1224|Proteobacteria,2U58S@28211|Alphaproteobacteria,2K6CX@204457|Sphingomonadales 204457|Sphingomonadales Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT,4HBT_3 PJD2_k127_1500248_0 161528.ED21_24686 6.611e-295 920.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,2K0XK@204457|Sphingomonadales 204457|Sphingomonadales M Penicillin-binding Protein - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase PJD2_k127_1500248_3 291985.CCSI01000001_gene1797 4.475e-141 449.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,2K0S6@204457|Sphingomonadales 204457|Sphingomonadales S Aerobic cobaltochelatase subunit CobS - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5,CbbQ_C,CobS_N PJD2_k127_150931_3 317655.Sala_2235 3.409e-96 319.0 COG2244@1|root,COG2244@2|Bacteria,1RC9S@1224|Proteobacteria,2U63T@28211|Alphaproteobacteria,2K3HG@204457|Sphingomonadales 204457|Sphingomonadales S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3 PJD2_k127_150931_2 1219035.NT2_02_00600 5.689e-158 501.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,2K0CN@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17 PJD2_k127_150931_4 279238.Saro_2323 2.573e-53 191.0 COG2050@1|root,COG2050@2|Bacteria,1MZPH@1224|Proteobacteria,2UDIQ@28211|Alphaproteobacteria,2K62E@204457|Sphingomonadales 204457|Sphingomonadales Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT PJD2_k127_150931_1 161528.ED21_28138 6.181e-177 563.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,2K2A7@204457|Sphingomonadales 204457|Sphingomonadales S AFG1 family ATPase - - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase PJD2_k127_150931_0 1096930.L284_20595 1.103e-318 985.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JZZC@204457|Sphingomonadales 204457|Sphingomonadales E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 PJD2_k127_155999_1 279238.Saro_2870 2.466e-254 793.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K18E@204457|Sphingomonadales 204457|Sphingomonadales CG Dehydrogenase - - 1.1.9.1,1.17.2.2 ko:K17760,ko:K21676 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 PJD2_k127_155999_0 161528.ED21_21809 1.501e-271 841.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales 204457|Sphingomonadales C belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh PJD2_k127_155999_8 1144305.PMI02_03124 1.35e-13 73.0 2AP9Q@1|root,31EBR@2|Bacteria,1P5YS@1224|Proteobacteria,2UYBB@28211|Alphaproteobacteria,2KC6B@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_155999_6 1030157.AFMP01000040_gene1498 2.822e-69 243.0 COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,2U7JH@28211|Alphaproteobacteria,2K0RN@204457|Sphingomonadales 204457|Sphingomonadales S membrane - - - - - - - - - - - - UPF0016 PJD2_k127_155999_3 935557.ATYB01000008_gene5043 2.619e-159 517.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,4B7X0@82115|Rhizobiaceae 28211|Alphaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH PJD2_k127_155999_7 864069.MicloDRAFT_00008540 2.376e-45 168.0 COG4244@1|root,COG4244@2|Bacteria,1RDSW@1224|Proteobacteria,2UDK1@28211|Alphaproteobacteria,1JYXE@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Predicted membrane protein (DUF2231) - - - - - - - - - - - - DUF2231 PJD2_k127_155999_2 1219035.NT2_01_02360 1.121e-182 576.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,2K0DQ@204457|Sphingomonadales 204457|Sphingomonadales S 2-nitropropane dioxygenase - - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO,ThiG PJD2_k127_155999_5 1144307.PMI04_04111 6.712e-129 438.0 28MAA@1|root,2ZAP0@2|Bacteria,1R5EZ@1224|Proteobacteria,2U43A@28211|Alphaproteobacteria,2JZVU@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_155999_4 291985.CCSI01000002_gene1765 2.982e-144 461.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2TVIF@28211|Alphaproteobacteria,2K0X5@204457|Sphingomonadales 204457|Sphingomonadales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp PJD2_k127_1579800_0 161528.ED21_27663 4.804e-107 350.0 COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2K0Y0@204457|Sphingomonadales 204457|Sphingomonadales I Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) ispDF - 2.7.7.60,4.6.1.12 ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB PJD2_k127_1579800_3 1248917.ANFX01000025_gene1255 1.75e-28 122.0 2AM6R@1|root,31C1C@2|Bacteria,1NP11@1224|Proteobacteria,2UKD9@28211|Alphaproteobacteria,2K72K@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_1579800_2 1382303.JPOM01000001_gene1306 2.018e-32 134.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,2KGJ8@204458|Caulobacterales 204458|Caulobacterales S Belongs to the CinA family - - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA PJD2_k127_1579800_1 291985.CCSI01000001_gene2361 3.948e-69 237.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2U7D8@28211|Alphaproteobacteria,2K41W@204457|Sphingomonadales 204457|Sphingomonadales I Oligoketide cyclase lipid transport protein - - - ko:K18588 - - - - ko00000 - - - Polyketide_cyc PJD2_k127_1644880_2 291985.CCSI01000002_gene1579 7.957e-164 521.0 COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TU15@28211|Alphaproteobacteria,2K1GE@204457|Sphingomonadales 204457|Sphingomonadales Q cytochrome P450 - - - - - - - - - - - - p450 PJD2_k127_1644880_1 279238.Saro_3161 9.131e-202 640.0 COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TRRZ@28211|Alphaproteobacteria,2K2K3@204457|Sphingomonadales 204457|Sphingomonadales IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C PJD2_k127_1644880_4 237727.NAP1_13808 4.982e-77 266.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2K4X5@204457|Sphingomonadales 204457|Sphingomonadales M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 PJD2_k127_1644880_3 1096930.L284_21425 1.731e-107 359.0 COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2TQJU@28211|Alphaproteobacteria,2K2JV@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF455 PJD2_k127_1644880_5 237727.NAP1_13798 1.455e-71 244.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,2K4IB@204457|Sphingomonadales 204457|Sphingomonadales O Alkyl hydroperoxide reductase bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA PJD2_k127_1644880_0 1219035.NT2_04_01670 0.0 1101.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,2K1YP@204457|Sphingomonadales 204457|Sphingomonadales H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE PJD2_k127_1644880_6 1144305.PMI02_03564 1.001e-31 133.0 COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria,2K04D@204457|Sphingomonadales 204457|Sphingomonadales S Peptidase, M28 - - - - - - - - - - - - PA,Peptidase_M28 PJD2_k127_1645883_6 291985.CCSI01000002_gene1509 2.375e-99 330.0 COG4850@1|root,COG4850@2|Bacteria,1R3ST@1224|Proteobacteria,2TUXT@28211|Alphaproteobacteria,2K4QX@204457|Sphingomonadales 204457|Sphingomonadales S Uncharacterized conserved protein (DUF2183) - - - - - - - - - - - - DUF2183 PJD2_k127_1645883_0 702113.PP1Y_AT37085 1.939e-193 618.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria,2K0E5@204457|Sphingomonadales 204457|Sphingomonadales S Peptidase M48 - - - - - - - - - - - - Peptidase_M48,TPR_16 PJD2_k127_1645883_9 291985.CCSI01000002_gene1506 3.171e-74 256.0 COG1651@1|root,COG1651@2|Bacteria,1MY3H@1224|Proteobacteria,2TTXR@28211|Alphaproteobacteria,2K3ZK@204457|Sphingomonadales 204457|Sphingomonadales O Protein-disulfide isomerase - - - - - - - - - - - - DSBA,Thioredoxin_4 PJD2_k127_1645883_8 1122970.AUHC01000011_gene2758 2.744e-82 286.0 COG0501@1|root,COG0501@2|Bacteria,1RH15@1224|Proteobacteria,2U9K7@28211|Alphaproteobacteria,2KCU5@204457|Sphingomonadales 204457|Sphingomonadales O Peptidase M48 - - - - - - - - - - - - Peptidase_M48 PJD2_k127_1645883_4 685035.ADAE01000005_gene1980 7.838e-114 370.0 COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,2U1W2@28211|Alphaproteobacteria,2K2E8@204457|Sphingomonadales 204457|Sphingomonadales S HD domain - - - - - - - - - - - - HD PJD2_k127_1645883_1 237727.NAP1_13388 2.419e-159 511.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U16F@28211|Alphaproteobacteria,2JZWJ@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - HATPase_c,His_kinase PJD2_k127_1645883_3 314225.ELI_12660 6.397e-144 460.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2TSPC@28211|Alphaproteobacteria,2K1DU@204457|Sphingomonadales 204457|Sphingomonadales T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg PJD2_k127_1645883_2 314225.ELI_12670 1.24e-154 491.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,2K19F@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N PJD2_k127_1645883_7 314225.ELI_12675 1.181e-89 310.0 COG3719@1|root,COG3719@2|Bacteria,1PTUN@1224|Proteobacteria,2TQUU@28211|Alphaproteobacteria,2K2KG@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the RNase T2 family - - 3.1.27.1 ko:K01166 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_T2 PJD2_k127_1645883_10 555793.WSK_3673 1.694e-70 242.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,2K4E6@204457|Sphingomonadales 204457|Sphingomonadales FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam PJD2_k127_1645883_11 383381.EH30_14705 1.597e-47 175.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,2K561@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 PJD2_k127_1645883_5 158500.BV97_02030 6.93e-107 355.0 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,2U6AR@28211|Alphaproteobacteria,2JZUN@204457|Sphingomonadales 204457|Sphingomonadales M peptidase - - - - - - - - - - - - Peptidase_M23 PJD2_k127_1659471_2 279238.Saro_0829 8.245e-91 305.0 29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2UBEB@28211|Alphaproteobacteria,2K5KS@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - Phenol_MetA_deg PJD2_k127_1659471_3 1030157.AFMP01000057_gene827 1.041e-57 209.0 COG1376@1|root,COG1376@2|Bacteria,1RKB2@1224|Proteobacteria,2UAA8@28211|Alphaproteobacteria,2K4DR@204457|Sphingomonadales 204457|Sphingomonadales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD_2 PJD2_k127_1659471_4 1081640.AGFU01000026_gene2585 1.535e-44 167.0 COG3134@1|root,COG3134@2|Bacteria,1NAZ4@1224|Proteobacteria,2UHWJ@28211|Alphaproteobacteria,2K54V@204457|Sphingomonadales 204457|Sphingomonadales S 17 kDa surface antigen - - - - - - - - - - - - Rick_17kDa_Anti PJD2_k127_1659471_5 1470591.BW41_01295 1.223e-25 119.0 COG0695@1|root,COG0695@2|Bacteria,1NZU3@1224|Proteobacteria,2UUCA@28211|Alphaproteobacteria,2K6F3@204457|Sphingomonadales 204457|Sphingomonadales O Glutaredoxin - - - - - - - - - - - - Glutaredoxin PJD2_k127_1659471_1 161528.ED21_22758 9.789e-96 331.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2U5E5@28211|Alphaproteobacteria,2K0SN@204457|Sphingomonadales 204457|Sphingomonadales D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 PJD2_k127_1659471_0 1479239.JQMU01000001_gene1797 4.368e-130 419.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,2K1E1@204457|Sphingomonadales 204457|Sphingomonadales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas PJD2_k127_1702732_7 279238.Saro_1020 7.997e-29 125.0 COG5285@1|root,COG5285@2|Bacteria,1R6HP@1224|Proteobacteria,2UHSD@28211|Alphaproteobacteria,2KB4J@204457|Sphingomonadales 204457|Sphingomonadales Q Phytanoyl-CoA dioxygenase (PhyH) - - - - - - - - - - - - PhyH PJD2_k127_1702732_0 517722.AEUE01000001_gene2821 1.955e-228 714.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,2K1W3@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine - - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP PJD2_k127_1702732_1 1088721.NSU_1015 3.185e-203 642.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2TU0C@28211|Alphaproteobacteria,2K329@204457|Sphingomonadales 204457|Sphingomonadales P Sodium:sulfate symporter transmembrane region - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp PJD2_k127_1702732_6 627192.SLG_13660 9.212e-40 156.0 COG3895@1|root,COG3895@2|Bacteria,1NEQI@1224|Proteobacteria,2UHAP@28211|Alphaproteobacteria,2K6Y8@204457|Sphingomonadales 204457|Sphingomonadales S Periplasmic Protein - - - - - - - - - - - - - PJD2_k127_1702732_5 1219035.NT2_10_01170 5.568e-89 297.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,2K0EN@204457|Sphingomonadales 204457|Sphingomonadales J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N PJD2_k127_1702732_4 161528.ED21_21424 9.25e-109 360.0 COG1407@1|root,COG1407@2|Bacteria,1RC5G@1224|Proteobacteria,2TU2T@28211|Alphaproteobacteria,2K25E@204457|Sphingomonadales 204457|Sphingomonadales S ICC-like phosphoesterases - - - ko:K06953 - - - - ko00000 - - - Metallophos PJD2_k127_1702732_2 161528.ED21_21429 4.443e-166 525.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,2K084@204457|Sphingomonadales 204457|Sphingomonadales H coproporphyrinogen III oxidase hemF - 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas PJD2_k127_1702732_3 2903.EOD15562 2.225e-124 406.0 COG0308@1|root,KOG1047@2759|Eukaryota 2759|Eukaryota E epoxide hydrolase activity RNPEPL1 GO:0001654,GO:0001990,GO:0001991,GO:0002002,GO:0002003,GO:0003008,GO:0003013,GO:0003044,GO:0003073,GO:0003081,GO:0003674,GO:0003824,GO:0004177,GO:0004301,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005794,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006629,GO:0006807,GO:0007275,GO:0007423,GO:0007568,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009897,GO:0009986,GO:0009987,GO:0010467,GO:0010817,GO:0012505,GO:0016020,GO:0016485,GO:0016486,GO:0016787,GO:0016801,GO:0016803,GO:0019538,GO:0030141,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0032501,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042445,GO:0042995,GO:0043005,GO:0043010,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045776,GO:0046872,GO:0046914,GO:0048513,GO:0048731,GO:0048856,GO:0050886,GO:0050897,GO:0051604,GO:0060041,GO:0065007,GO:0065008,GO:0070006,GO:0070011,GO:0070013,GO:0071704,GO:0071944,GO:0097458,GO:0097708,GO:0098552,GO:0099503,GO:0120025,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.3.2.6,3.4.11.6 ko:K01254,ko:K01260,ko:K09605,ko:K09606 ko00590,ko01100,map00590,map01100 - R03057 RC00838 ko00000,ko00001,ko01000,ko01002 - - - Leuk-A4-hydro_C,Peptidase_M1 PJD2_k127_1738135_7 1219035.NT2_01_02770 1.282e-49 178.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,2K0H3@204457|Sphingomonadales 204457|Sphingomonadales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 PJD2_k127_1738135_8 1248917.ANFX01000008_gene293 7.58e-20 90.0 2AMAU@1|root,31C5X@2|Bacteria,1NMZT@1224|Proteobacteria,2UN1A@28211|Alphaproteobacteria,2K7FA@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_1738135_1 161528.ED21_29386 4.183e-294 914.0 COG2312@1|root,COG2518@1|root,COG2312@2|Bacteria,COG2518@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,2KEGF@204457|Sphingomonadales 204457|Sphingomonadales O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - - - - - - - - - - Erythro_esteras,PCMT PJD2_k127_1738135_4 1122970.AUHC01000002_gene1267 2.815e-127 415.0 COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,2UBDH@28211|Alphaproteobacteria,2K2BR@204457|Sphingomonadales 204457|Sphingomonadales V beta-lactamase - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2,Peptidase_S13 PJD2_k127_1738135_6 1174684.EBMC1_06820 7.586e-94 316.0 COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,2TT0U@28211|Alphaproteobacteria,2K3CF@204457|Sphingomonadales 204457|Sphingomonadales S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI PJD2_k127_1738135_0 1144305.PMI02_02907 0.0 1552.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2K1KW@204457|Sphingomonadales 204457|Sphingomonadales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 PJD2_k127_1738135_3 291985.CCSI01000007_gene513 8.661e-135 443.0 COG3920@1|root,COG5278@1|root,COG3920@2|Bacteria,COG5278@2|Bacteria,1R967@1224|Proteobacteria,2TURX@28211|Alphaproteobacteria,2K35R@204457|Sphingomonadales 204457|Sphingomonadales T CHASE3 domain - - - - - - - - - - - - CHASE3,HWE_HK PJD2_k127_1738135_5 314225.ELI_14325 1.387e-119 395.0 COG0668@1|root,COG0668@2|Bacteria,1MW7V@1224|Proteobacteria,2TT0A@28211|Alphaproteobacteria,2K1AZ@204457|Sphingomonadales 204457|Sphingomonadales M Small-conductance mechanosensitive channel - - - - - - - - - - - - MS_channel PJD2_k127_1738135_2 291985.CCSI01000007_gene515 1.303e-169 536.0 COG1222@1|root,COG1222@2|Bacteria,1QTV4@1224|Proteobacteria,2U0Q7@28211|Alphaproteobacteria,2K0N9@204457|Sphingomonadales 204457|Sphingomonadales O Belongs to the AAA ATPase family - - - ko:K13525 ko04141,ko05134,map04141,map05134 M00400,M00403 - - ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 3.A.16.1 - - AAA,CDC48_2,CDC48_N PJD2_k127_1742161_1 158500.BV97_01366 3.875e-114 372.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,2K0A5@204457|Sphingomonadales 204457|Sphingomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt PJD2_k127_1742161_0 1219035.NT2_02_01880 9.647e-133 428.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,2K03H@204457|Sphingomonadales 204457|Sphingomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N PJD2_k127_1759693_4 161528.ED21_19347 9.271e-56 196.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2TT46@28211|Alphaproteobacteria,2K26A@204457|Sphingomonadales 204457|Sphingomonadales C Catalyzes the reversible hydration of fumarate to (S)- malate - - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C PJD2_k127_1759693_0 291985.CCSI01000002_gene1455 1.959e-139 461.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U103@28211|Alphaproteobacteria,2K0W4@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - HATPase_c,His_kinase PJD2_k127_1759693_2 1248917.ANFX01000005_gene158 3.565e-115 376.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2UCDH@28211|Alphaproteobacteria,2KD3F@204457|Sphingomonadales 204457|Sphingomonadales KT LytTr DNA-binding domain - - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg PJD2_k127_1759693_5 1219035.NT2_04_03240 1.4e-27 116.0 29GQI@1|root,3181U@2|Bacteria,1P6Y8@1224|Proteobacteria,2UX71@28211|Alphaproteobacteria,2K7W7@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_1759693_3 1219035.NT2_04_03230 6.891e-89 302.0 COG1597@1|root,COG1597@2|Bacteria,1RGHZ@1224|Proteobacteria,2U7RG@28211|Alphaproteobacteria,2K2EV@204457|Sphingomonadales 204457|Sphingomonadales I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - - - - - - - - - - DAGK_cat PJD2_k127_1759693_1 517722.AEUE01000001_gene2430 2.376e-133 431.0 COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,2U1GX@28211|Alphaproteobacteria,2K28P@204457|Sphingomonadales 204457|Sphingomonadales S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos PJD2_k127_1785532_1 1219035.NT2_01_02560 2.912e-134 435.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,2K0KW@204457|Sphingomonadales 204457|Sphingomonadales K transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg PJD2_k127_1785532_4 279238.Saro_0420 8.576e-55 194.0 2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2UAVD@28211|Alphaproteobacteria,2K6EC@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_1785532_3 161528.ED21_17827 8.975e-72 245.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,2K4M7@204457|Sphingomonadales 204457|Sphingomonadales L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC PJD2_k127_1785532_6 1219035.NT2_01_02530 4.659e-38 153.0 COG2329@1|root,COG2329@2|Bacteria,1Q2JU@1224|Proteobacteria,2UIP8@28211|Alphaproteobacteria,2KDKI@204457|Sphingomonadales 204457|Sphingomonadales S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM PJD2_k127_1785532_5 1088721.NSU_1308 1.434e-39 159.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2U98B@28211|Alphaproteobacteria,2K5XC@204457|Sphingomonadales 204457|Sphingomonadales P Belongs to the ArsC family - - - - - - - - - - - - ArsC PJD2_k127_1785532_0 161528.ED21_17817 2.032e-134 447.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,2TV4M@28211|Alphaproteobacteria,2K0H8@204457|Sphingomonadales 204457|Sphingomonadales C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD PJD2_k127_1785532_2 291985.CCSI01000002_gene1761 3.312e-111 364.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,2K0DH@204457|Sphingomonadales 204457|Sphingomonadales H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 PJD2_k127_1789024_8 314225.ELI_02715 7.133e-37 139.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria,2K0T4@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ PJD2_k127_1789024_6 161528.ED21_24726 7.476e-69 235.0 COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,2K4ID@204457|Sphingomonadales 204457|Sphingomonadales I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS PJD2_k127_1789024_3 279238.Saro_0909 1.875e-132 428.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,2K1V9@204457|Sphingomonadales 204457|Sphingomonadales U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 PJD2_k127_1789024_4 291985.CCSI01000001_gene1807 8.452e-123 417.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TQSH@28211|Alphaproteobacteria,2K0XW@204457|Sphingomonadales 204457|Sphingomonadales S permease - - - - - - - - - - - - AI-2E_transport PJD2_k127_1789024_2 161528.ED21_24711 7.947e-155 505.0 COG2267@1|root,COG2267@2|Bacteria,1MVDA@1224|Proteobacteria,2TUDQ@28211|Alphaproteobacteria,2K1MR@204457|Sphingomonadales 204457|Sphingomonadales I Protein of unknown function (DUF3089) - - - - - - - - - - - - DUF3089 PJD2_k127_1789024_7 1219035.NT2_01_04510 9.712e-68 234.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,2K4GA@204457|Sphingomonadales 204457|Sphingomonadales L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA - - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX PJD2_k127_1789024_0 158500.BV97_00705 2.023e-191 612.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2TSMA@28211|Alphaproteobacteria,2K1FG@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 PJD2_k127_1789024_5 237727.NAP1_01615 7.249e-78 267.0 COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,2UBX1@28211|Alphaproteobacteria,2K6FP@204457|Sphingomonadales 204457|Sphingomonadales GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 PJD2_k127_1789024_1 291985.CCSI01000004_gene771 5.691e-184 583.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria,2K0JG@204457|Sphingomonadales 204457|Sphingomonadales F dGTPase family. Type 2 subfamily dgt - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc PJD2_k127_18049_6 1248917.ANFX01000029_gene2618 9.125e-74 251.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,2K01R@204457|Sphingomonadales 204457|Sphingomonadales C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N PJD2_k127_18049_8 383381.EH30_00565 3.586e-52 189.0 COG5317@1|root,COG5317@2|Bacteria,1N9DI@1224|Proteobacteria,2UFAD@28211|Alphaproteobacteria,2K6FU@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1465) - - - ko:K13592 ko04112,map04112 - - - ko00000,ko00001 - - - DUF1465 PJD2_k127_18049_9 1219035.NT2_05_02570 6.914e-26 108.0 COG5481@1|root,COG5481@2|Bacteria,1NG9U@1224|Proteobacteria,2UFXJ@28211|Alphaproteobacteria,2K6XC@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF465) - - - - - - - - - - - - DUF465 PJD2_k127_18049_11 1248917.ANFX01000046_gene609 2.87e-11 70.0 COG5570@1|root,COG5570@2|Bacteria,1NGRE@1224|Proteobacteria,2UJAX@28211|Alphaproteobacteria,2K7RY@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF465) - - - - - - - - - - - - DUF465 PJD2_k127_18049_0 314225.ELI_00500 0.0 1187.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,2TR3Z@28211|Alphaproteobacteria,2K17Q@204457|Sphingomonadales 204457|Sphingomonadales T Belongs to the PEP-utilizing enzyme family ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C PJD2_k127_18049_4 314225.ELI_00505 3.543e-81 280.0 COG1426@1|root,COG1426@2|Bacteria,1RGRW@1224|Proteobacteria,2U92Y@28211|Alphaproteobacteria,2KD3D@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF4115,HTH_25 PJD2_k127_18049_3 314225.ELI_00510 4.068e-99 336.0 COG1729@1|root,COG1729@2|Bacteria,1R8C4@1224|Proteobacteria,2VBNQ@28211|Alphaproteobacteria,2K0FK@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri PJD2_k127_18049_1 314225.ELI_00515 9.551e-122 398.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,2K3YA@204457|Sphingomonadales 204457|Sphingomonadales D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3 PJD2_k127_18049_7 517722.AEUE01000008_gene168 1.063e-69 251.0 COG1376@1|root,COG1376@2|Bacteria,1NQ27@1224|Proteobacteria,2UQAQ@28211|Alphaproteobacteria,2KE24@204457|Sphingomonadales 204457|Sphingomonadales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD PJD2_k127_18049_2 291985.CCSI01000003_gene184 6.835e-113 370.0 COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2TURT@28211|Alphaproteobacteria,2K2E9@204457|Sphingomonadales 204457|Sphingomonadales E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core PJD2_k127_18049_5 1123270.ATUR01000004_gene1574 2.434e-79 272.0 COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2TQQ2@28211|Alphaproteobacteria,2K42I@204457|Sphingomonadales 204457|Sphingomonadales I dehydratase - - - - - - - - - - - - MaoC_dehydratas PJD2_k127_18049_10 391600.ABRU01000042_gene2489 4.467e-19 98.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,2KGV9@204458|Caulobacterales 204458|Caulobacterales G HpcH/HpaI aldolase/citrate lyase family - - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI PJD2_k127_1839547_1 1121033.AUCF01000026_gene2971 8.419e-113 372.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2TRKT@28211|Alphaproteobacteria,2JQTN@204441|Rhodospirillales 204441|Rhodospirillales H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - - - - - - - - - - - HemN_C,Radical_SAM PJD2_k127_1839547_0 1522072.IL54_1595 3.171e-140 453.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,2K041@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM PJD2_k127_1839547_2 1449076.JOOE01000001_gene2178 6.705e-41 154.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2TSXZ@28211|Alphaproteobacteria,2K3QP@204457|Sphingomonadales 204457|Sphingomonadales P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 PJD2_k127_1856502_0 279238.Saro_1602 8.57e-255 796.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2TVFM@28211|Alphaproteobacteria,2K10T@204457|Sphingomonadales 204457|Sphingomonadales J Beta-Casp domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL PJD2_k127_1856502_2 388051.AUFE01000017_gene5722 6.164e-82 289.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2VJI6@28216|Betaproteobacteria,1K64P@119060|Burkholderiaceae 28216|Betaproteobacteria F Ribose-phosphate pyrophosphokinase - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N PJD2_k127_1856502_1 450851.PHZ_p0142 1.856e-178 571.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria,2KJGW@204458|Caulobacterales 204458|Caulobacterales F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C PJD2_k127_1904431_4 1248917.ANFX01000022_gene680 8.854e-129 417.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2K0J0@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT PJD2_k127_1904431_1 1545915.JROG01000004_gene2402 4.181e-213 668.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,2K0J1@204457|Sphingomonadales 204457|Sphingomonadales EH Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 PJD2_k127_1904431_2 1122612.AUBA01000009_gene2023 7.568e-168 536.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria,2K14F@204457|Sphingomonadales 204457|Sphingomonadales M Glycosyl transferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_1904431_8 161528.ED21_31829 8.471e-43 162.0 2C7KN@1|root,336M6@2|Bacteria,1N4WC@1224|Proteobacteria,2UF7X@28211|Alphaproteobacteria,2K6DP@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_1904431_7 161528.ED21_31839 2.295e-65 230.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,2U1HF@28211|Alphaproteobacteria,2K4SR@204457|Sphingomonadales 204457|Sphingomonadales K transcriptional - - - - - - - - - - - - PadR PJD2_k127_1904431_0 237727.NAP1_01190 1.261e-230 722.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2TQVF@28211|Alphaproteobacteria,2K1Z2@204457|Sphingomonadales 204457|Sphingomonadales L ATPase related to the helicase subunit of the Holliday junction resolvase - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N PJD2_k127_1904431_6 1219035.NT2_01_06410 1.23e-115 392.0 2CF7S@1|root,2ZB6P@2|Bacteria,1RF1X@1224|Proteobacteria,2TW2Z@28211|Alphaproteobacteria,2KE9J@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_1904431_3 392499.Swit_5283 1.183e-142 456.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,2K0RM@204457|Sphingomonadales 204457|Sphingomonadales L exodeoxyribonuclease III - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos PJD2_k127_1904431_5 702113.PP1Y_AT4446 5.591e-121 392.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,2K0K7@204457|Sphingomonadales 204457|Sphingomonadales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 PJD2_k127_1909731_6 314225.ELI_11445 1.366e-82 283.0 2E521@1|root,32ZVA@2|Bacteria,1RF95@1224|Proteobacteria,2U8QW@28211|Alphaproteobacteria,2K2DR@204457|Sphingomonadales 204457|Sphingomonadales S zinc-ribbon domain - - - - - - - - - - - - zinc_ribbon_4 PJD2_k127_1909731_2 1044.EH31_05210 1.241e-203 639.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria,2K0C2@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N PJD2_k127_1909731_4 314225.ELI_11870 7.996e-155 502.0 COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,2U0ZX@28211|Alphaproteobacteria,2K1KI@204457|Sphingomonadales 204457|Sphingomonadales P phosphate-selective porin - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P PJD2_k127_1909731_0 1502850.FG91_04068 0.0 1315.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,2TRCG@28211|Alphaproteobacteria,2K0ND@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_1909731_1 555793.WSK_2105 0.0 1073.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,2K02P@204457|Sphingomonadales 204457|Sphingomonadales D DNA segregation ATPase FtsK SpoIIIE ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma PJD2_k127_1909731_7 517722.AEUE01000001_gene2606 3.367e-58 209.0 COG0352@1|root,COG0352@2|Bacteria,1RKGX@1224|Proteobacteria,2UB4W@28211|Alphaproteobacteria,2K57F@204457|Sphingomonadales 204457|Sphingomonadales H Thiamine monophosphate synthase - - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI PJD2_k127_1909731_5 383381.EH30_13760 1.648e-95 317.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,2K0C6@204457|Sphingomonadales 204457|Sphingomonadales S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N PJD2_k127_1909731_3 291985.CCSI01000002_gene1692 2.051e-199 627.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,2K0BN@204457|Sphingomonadales 204457|Sphingomonadales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - DUF294,GlnD_UR_UTase,HD PJD2_k127_1913957_0 314225.ELI_14320 3.277e-268 831.0 COG1222@1|root,COG1222@2|Bacteria,1QTV4@1224|Proteobacteria,2U0Q7@28211|Alphaproteobacteria,2K0N9@204457|Sphingomonadales 204457|Sphingomonadales O Belongs to the AAA ATPase family - - - ko:K13525 ko04141,ko05134,map04141,map05134 M00400,M00403 - - ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 3.A.16.1 - - AAA,CDC48_2,CDC48_N PJD2_k127_1913957_1 685035.ADAE01000002_gene2071 5.135e-136 435.0 COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,2K0EF@204457|Sphingomonadales 204457|Sphingomonadales I Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit scoA - 2.8.3.5 ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans PJD2_k127_1913957_4 383381.EH30_12115 1.043e-42 172.0 29W6C@1|root,30HRF@2|Bacteria,1NJUD@1224|Proteobacteria,2UM17@28211|Alphaproteobacteria,2K7G6@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_1913957_2 1219049.SP5_076_00260 6.042e-123 396.0 COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria,2JZXA@204457|Sphingomonadales 204457|Sphingomonadales I Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit scoB - 2.8.3.5 ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans PJD2_k127_1913957_3 1144325.PMI22_00773 9.912e-116 379.0 COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,1RRX5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 2-nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO PJD2_k127_1937524_7 1120705.FG95_03006 3.005e-12 66.0 COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2K165@204457|Sphingomonadales 204457|Sphingomonadales FL Metal binding domain of Ada ada - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N PJD2_k127_1937524_4 1502850.FG91_01392 6.025e-93 313.0 COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2U3CR@28211|Alphaproteobacteria,2K4EU@204457|Sphingomonadales 204457|Sphingomonadales G COG2513 PEP phosphonomutase and related enzymes - - - - - - - - - - - - PEP_mutase PJD2_k127_1937524_5 1248917.ANFX01000032_gene904 1.028e-84 297.0 COG1266@1|root,COG1266@2|Bacteria,1RJQW@1224|Proteobacteria,2UB06@28211|Alphaproteobacteria,2K5HR@204457|Sphingomonadales 204457|Sphingomonadales S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi PJD2_k127_1937524_3 1122970.AUHC01000008_gene74 3.4e-96 319.0 COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2VFCA@28211|Alphaproteobacteria,2K6R8@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N PJD2_k127_1937524_0 1219035.NT2_02_01820 0.0 1157.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,2K0DV@204457|Sphingomonadales 204457|Sphingomonadales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C PJD2_k127_1937524_6 314225.ELI_08710 7.142e-82 278.0 29BA9@1|root,2ZY8N@2|Bacteria,1RJEZ@1224|Proteobacteria,2U9H3@28211|Alphaproteobacteria,2K4P7@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 PJD2_k127_1937524_2 1219035.NT2_02_01800 2.141e-125 405.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria,2K0F2@204457|Sphingomonadales 204457|Sphingomonadales G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA PJD2_k127_1937524_1 237727.NAP1_08000 3.251e-287 903.0 COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,2JZUK@204457|Sphingomonadales 204457|Sphingomonadales H Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) - - 6.6.1.2 ko:K09883 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobT,CobT_C PJD2_k127_1961881_0 161528.ED21_22528 7.714e-211 661.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,2K0M5@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C PJD2_k127_1961881_1 279238.Saro_2502 3.941e-33 132.0 COG0183@1|root,COG0183@2|Bacteria,1MVPC@1224|Proteobacteria,2VEVD@28211|Alphaproteobacteria,2K31W@204457|Sphingomonadales 204457|Sphingomonadales I acetyl-coa acetyltransferase - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - - PJD2_k127_1969894_12 314225.ELI_07710 6.851e-43 158.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2K061@204457|Sphingomonadales 204457|Sphingomonadales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N PJD2_k127_1969894_11 1304878.AUGD01000004_gene5253 8.179e-51 191.0 2919Q@1|root,32EZ8@2|Bacteria,1R3DK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - PJD2_k127_1969894_0 1096930.L284_06135 0.0 1436.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,2K28K@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD PJD2_k127_1969894_9 1449076.JOOE01000001_gene1700 9.246e-63 228.0 COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2U5Y7@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Diacylglycerol kinase - - - - - - - - - - - - DAGK_cat PJD2_k127_1969894_6 314225.ELI_07725 5e-92 310.0 COG0500@1|root,COG0500@2|Bacteria,1QYDK@1224|Proteobacteria,2TXPI@28211|Alphaproteobacteria,2KEIG@204457|Sphingomonadales 204457|Sphingomonadales Q Methyltransferase small domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 PJD2_k127_1969894_3 685035.ADAE01000002_gene2715 5.896e-203 635.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2K1TR@204457|Sphingomonadales 204457|Sphingomonadales L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA PJD2_k127_1969894_4 1122970.AUHC01000001_gene773 5.586e-170 553.0 COG5316@1|root,COG5316@2|Bacteria,1MXED@1224|Proteobacteria,2U1NI@28211|Alphaproteobacteria,2K0YR@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_1969894_2 1248917.ANFX01000011_gene196 4.703e-208 661.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2U2ZN@28211|Alphaproteobacteria,2K1T4@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - DUF4139 PJD2_k127_1969894_13 279238.Saro_2531 1.226e-36 144.0 COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,2U5F8@28211|Alphaproteobacteria,2K3WW@204457|Sphingomonadales 204457|Sphingomonadales S Hexapeptide repeat of succinyl-transferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac PJD2_k127_1969894_15 279238.Saro_2530 1.718e-32 132.0 COG0110@1|root,COG0110@2|Bacteria,1RICC@1224|Proteobacteria,2UCRH@28211|Alphaproteobacteria,2K6JQ@204457|Sphingomonadales 204457|Sphingomonadales S Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep,Hexapep_2 PJD2_k127_1969894_1 314225.ELI_07735 0.0 1044.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K0WG@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - 2.7.13.3 ko:K13587 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4,PAS_8,Response_reg PJD2_k127_1969894_8 1219035.NT2_02_04250 3.884e-68 237.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2UB7Z@28211|Alphaproteobacteria,2K4SW@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09928 - - - - ko00000 - - - DUF2062 PJD2_k127_1969894_7 158500.BV97_00993 1.07e-79 268.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,2K3YM@204457|Sphingomonadales 204457|Sphingomonadales O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB PJD2_k127_1969894_14 745310.G432_18265 1.364e-33 143.0 COG3668@1|root,32ZH9@2|Bacteria,1N7YH@1224|Proteobacteria,2UC0X@28211|Alphaproteobacteria,2K645@204457|Sphingomonadales 204457|Sphingomonadales S Plasmid stabilization - - - - - - - - - - - - - PJD2_k127_1969894_5 1479239.JQMU01000001_gene532 3.017e-160 513.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,2K09B@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS PJD2_k127_1969894_10 1122970.AUHC01000005_gene1972 2.969e-54 198.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,2K0PK@204457|Sphingomonadales 204457|Sphingomonadales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT PJD2_k127_1982083_1 314225.ELI_14040 1.729e-56 223.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2K2BG@204457|Sphingomonadales 204457|Sphingomonadales S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C PJD2_k127_1982083_2 161528.ED21_20239 3.628e-33 133.0 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TWYB@28211|Alphaproteobacteria,2KEG0@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 PJD2_k127_1982083_0 685035.ADAE01000023_gene1718 2.155e-143 483.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2U17R@28211|Alphaproteobacteria,2K18P@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the ompA family - - - - - - - - - - - - Autotransporter,OMP_b-brl,OmpA PJD2_k127_1982083_3 314225.ELI_13945 2.198e-23 113.0 COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,2UC22@28211|Alphaproteobacteria,2K541@204457|Sphingomonadales 204457|Sphingomonadales P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodC - 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - - Sod_Cu PJD2_k127_1987914_17 1248917.ANFX01000014_gene1365 2.868e-93 325.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,2K1NZ@204457|Sphingomonadales 204457|Sphingomonadales S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 PJD2_k127_1987914_15 314225.ELI_10300 1.066e-97 344.0 2952T@1|root,2ZSFJ@2|Bacteria,1RGF9@1224|Proteobacteria,2U83E@28211|Alphaproteobacteria,2K2TA@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_1987914_19 1219035.NT2_05_01520 6.514e-71 246.0 2C58E@1|root,32V5I@2|Bacteria,1N13T@1224|Proteobacteria,2UBSB@28211|Alphaproteobacteria,2K675@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - DUF4129 PJD2_k127_1987914_8 1122970.AUHC01000015_gene2525 1.806e-144 464.0 COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,2TSUT@28211|Alphaproteobacteria,2K0AM@204457|Sphingomonadales 204457|Sphingomonadales E Prephenate dehydratase - - 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - - PDT PJD2_k127_1987914_20 1219035.NT2_05_01540 4.928e-67 236.0 COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,2K42S@204457|Sphingomonadales 204457|Sphingomonadales C cytochrome C - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C PJD2_k127_1987914_12 1248917.ANFX01000014_gene1370 1.659e-114 378.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria,2K02A@204457|Sphingomonadales 204457|Sphingomonadales J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ PJD2_k127_1987914_4 383381.EH30_11155 3.381e-168 539.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria,2K1HK@204457|Sphingomonadales 204457|Sphingomonadales FP exopolyphosphatase - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA PJD2_k127_1987914_18 627192.SLG_14100 8.577e-89 299.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2U5H3@28211|Alphaproteobacteria,2K0BZ@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the pseudouridine synthase RsuA family rluE - 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 PJD2_k127_1987914_9 291985.CCSI01000003_gene322 7.239e-142 455.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria,2K00V@204457|Sphingomonadales 204457|Sphingomonadales S Rossmann fold nucleotide-binding protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox PJD2_k127_1987914_14 161528.ED21_23053 7.954e-108 360.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,2K24Q@204457|Sphingomonadales 204457|Sphingomonadales H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase,Phos_pyr_kin PJD2_k127_1987914_25 1122970.AUHC01000013_gene1053 2.238e-39 147.0 COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,2UFME@28211|Alphaproteobacteria,2K78J@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09984 - - - - ko00000 - - - DUF1272 PJD2_k127_1987914_0 1044.EH31_16140 4.21e-233 728.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,2JZV4@204457|Sphingomonadales 204457|Sphingomonadales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV PJD2_k127_1987914_6 314225.ELI_10240 1.94e-152 494.0 COG1301@1|root,COG1301@2|Bacteria,1MVID@1224|Proteobacteria,2TUR0@28211|Alphaproteobacteria,2K09V@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF PJD2_k127_1987914_16 517722.AEUE01000010_gene583 3.683e-95 317.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,2K112@204457|Sphingomonadales 204457|Sphingomonadales P Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N PJD2_k127_1987914_7 291985.CCSI01000003_gene317 1.3e-151 490.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TVPN@28211|Alphaproteobacteria,2K11M@204457|Sphingomonadales 204457|Sphingomonadales S permease - - - - - - - - - - - - AI-2E_transport PJD2_k127_1987914_13 685035.ADAE01000007_gene1313 6.811e-110 357.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2TUUZ@28211|Alphaproteobacteria,2K0TM@204457|Sphingomonadales 204457|Sphingomonadales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_1987914_1 291985.CCSI01000003_gene314 5.104e-204 649.0 COG3614@1|root,COG3920@1|root,COG3614@2|Bacteria,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria,2U4QM@28211|Alphaproteobacteria,2K26R@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - CHASE,HWE_HK PJD2_k127_1987914_11 161528.ED21_23093 1.793e-133 432.0 COG0784@1|root,COG1595@1|root,COG0784@2|Bacteria,COG1595@2|Bacteria,1MX3Y@1224|Proteobacteria,2TT2R@28211|Alphaproteobacteria,2K0S1@204457|Sphingomonadales 204457|Sphingomonadales T In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media - - - - - - - - - - - - Response_reg,Sigma70_r4_2 PJD2_k127_1987914_27 426355.Mrad2831_0850 1.796e-06 54.0 2DI4Z@1|root,3021H@2|Bacteria,1PN4F@1224|Proteobacteria,2V0QX@28211|Alphaproteobacteria,1JWQA@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_1987914_24 161528.ED21_23103 7.763e-45 169.0 COG0784@1|root,COG0784@2|Bacteria,1N8QF@1224|Proteobacteria,2UFT1@28211|Alphaproteobacteria,2K744@204457|Sphingomonadales 204457|Sphingomonadales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg PJD2_k127_1987914_3 1122612.AUBA01000019_gene3037 7.736e-188 594.0 COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,2TUU2@28211|Alphaproteobacteria,2K0BS@204457|Sphingomonadales 204457|Sphingomonadales K acetyltransferase - - - - - - - - - - - - - PJD2_k127_1987914_10 1088721.NSU_2462 8.249e-138 448.0 COG3239@1|root,COG3239@2|Bacteria,1MVY5@1224|Proteobacteria,2U156@28211|Alphaproteobacteria,2K0CR@204457|Sphingomonadales 204457|Sphingomonadales I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase PJD2_k127_1987914_5 291985.CCSI01000003_gene306 4.8e-162 529.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,2K1ZM@204457|Sphingomonadales 204457|Sphingomonadales S YjgP YjgQ family - - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ PJD2_k127_1987914_2 1479239.JQMU01000001_gene933 1.154e-196 620.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2U55Q@28211|Alphaproteobacteria,2K07C@204457|Sphingomonadales 204457|Sphingomonadales S YjgP YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ PJD2_k127_1987914_21 1479239.JQMU01000001_gene931 4.156e-56 201.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria,2K5BT@204457|Sphingomonadales 204457|Sphingomonadales S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS PJD2_k127_1987914_22 161528.ED21_23143 2.247e-55 203.0 COG5490@1|root,COG5490@2|Bacteria,1N3RI@1224|Proteobacteria,2UDM8@28211|Alphaproteobacteria,2KDF6@204457|Sphingomonadales 204457|Sphingomonadales S Phasin protein - - - - - - - - - - - - Phasin_2 PJD2_k127_1987914_23 1122970.AUHC01000013_gene1038 1.655e-45 166.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,2K0U9@204457|Sphingomonadales 204457|Sphingomonadales I poly(R)-hydroxyalkanoic acid synthase phaC - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N PJD2_k127_2003673_1 291985.CCSI01000002_gene1471 9.529e-90 298.0 2AFT8@1|root,31D88@2|Bacteria,1REHW@1224|Proteobacteria,2U8QX@28211|Alphaproteobacteria,2KDFQ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2003673_2 715226.ABI_40890 2.574e-55 198.0 COG3832@1|root,COG3832@2|Bacteria,1RJKI@1224|Proteobacteria,2UAQG@28211|Alphaproteobacteria,2KGNQ@204458|Caulobacterales 204458|Caulobacterales S PFAM Activator of Hsp90 ATPase 1 family protein - - - - - - - - - - - - AHSA1 PJD2_k127_2003673_0 1219035.NT2_04_03160 4.108e-154 488.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2K0MM@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG,ThiS PJD2_k127_200652_4 314225.ELI_01790 9.795e-66 239.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2TQSA@28211|Alphaproteobacteria,2K0IS@204457|Sphingomonadales 204457|Sphingomonadales D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE PJD2_k127_200652_3 1219035.NT2_05_03990 1.896e-177 569.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,2K1GM@204457|Sphingomonadales 204457|Sphingomonadales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M PJD2_k127_200652_2 314225.ELI_01780 1.566e-196 616.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2K18Y@204457|Sphingomonadales 204457|Sphingomonadales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 PJD2_k127_200652_0 314225.ELI_01775 4.167e-223 708.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,2K1N2@204457|Sphingomonadales 204457|Sphingomonadales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M PJD2_k127_200652_1 279238.Saro_1128 1.269e-219 691.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria,2K12F@204457|Sphingomonadales 204457|Sphingomonadales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M PJD2_k127_2065055_13 1044.EH31_11605 3.198e-31 130.0 COG1266@1|root,COG1266@2|Bacteria,1NN54@1224|Proteobacteria,2UUZE@28211|Alphaproteobacteria,2K77V@204457|Sphingomonadales 204457|Sphingomonadales S CAAX protease self-immunity - - - - - - - - - - - - Abi PJD2_k127_2065055_4 314225.ELI_14500 2.574e-153 490.0 COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2TRDT@28211|Alphaproteobacteria,2K203@204457|Sphingomonadales 204457|Sphingomonadales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 PJD2_k127_2065055_12 517722.AEUE01000002_gene2304 7.631e-36 139.0 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,2K5Z1@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the UPF0335 family - - - - - - - - - - - - DUF2312 PJD2_k127_2065055_11 517722.AEUE01000002_gene2303 4.143e-43 162.0 COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,2UC11@28211|Alphaproteobacteria,2K5WC@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09948 - - - - ko00000 - - - DUF1244 PJD2_k127_2065055_0 161528.ED21_20829 6.671e-261 817.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,2K07D@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C PJD2_k127_2065055_1 1219035.NT2_01_02610 2.004e-221 693.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria,2K0M4@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX2 - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c PJD2_k127_2065055_8 1248917.ANFX01000049_gene1622 3.93e-82 296.0 COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2TTNQ@28211|Alphaproteobacteria,2K0KH@204457|Sphingomonadales 204457|Sphingomonadales Q Methionine biosynthesis protein MetW metW - - - - - - - - - - - MetW PJD2_k127_2065055_2 314225.ELI_11410 4.415e-200 627.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2TQYA@28211|Alphaproteobacteria,2JZX2@204457|Sphingomonadales 204457|Sphingomonadales E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metXA - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 PJD2_k127_2065055_3 314225.ELI_11415 8.616e-156 522.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria,2JZXY@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 PJD2_k127_2065055_5 237727.NAP1_15028 3.974e-136 449.0 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria,2K18X@204457|Sphingomonadales 204457|Sphingomonadales E Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate tyrC GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00220 ko00400,ko00401,ko01100,ko01110,ko01230,map00400,map00401,map01100,map01110,map01230 M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH PJD2_k127_2065055_7 314225.ELI_11425 5.948e-87 294.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria,2K3XJ@204457|Sphingomonadales 204457|Sphingomonadales I Acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase PJD2_k127_2065055_9 1219035.NT2_12_00880 2.226e-64 234.0 COG1434@1|root,COG1434@2|Bacteria,1RHMV@1224|Proteobacteria,2U957@28211|Alphaproteobacteria,2K4KS@204457|Sphingomonadales 204457|Sphingomonadales S DUF218 domain - - - - - - - - - - - - DUF218 PJD2_k127_2065055_6 314225.ELI_11435 4.408e-104 351.0 COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria,2K43P@204457|Sphingomonadales 204457|Sphingomonadales D Cell division protein ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX PJD2_k127_2065055_10 1219035.NT2_12_00900 1.298e-48 174.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2TS9Y@28211|Alphaproteobacteria,2JZVB@204457|Sphingomonadales 204457|Sphingomonadales D cell division ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran PJD2_k127_2089214_0 314225.ELI_00480 1.485e-222 704.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,2K01R@204457|Sphingomonadales 204457|Sphingomonadales C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N PJD2_k127_2089214_3 291985.CCSI01000003_gene197 7.542e-148 488.0 COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2K18T@204457|Sphingomonadales 204457|Sphingomonadales S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B PJD2_k127_2089214_4 161528.ED21_22253 2.179e-86 299.0 2BX8M@1|root,31H0R@2|Bacteria,1MYMI@1224|Proteobacteria,2UB1B@28211|Alphaproteobacteria,2K27Q@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF4230) - - - - - - - - - - - - DUF4230 PJD2_k127_2089214_5 190650.CC_3505 2.627e-74 259.0 2919Q@1|root,331DT@2|Bacteria,1RD8H@1224|Proteobacteria,2U8WH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_2089214_7 158500.BV97_01553 2.247e-38 150.0 2AM7Z@1|root,31C2N@2|Bacteria,1P30V@1224|Proteobacteria,2UV1J@28211|Alphaproteobacteria,2KBB5@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - HTH_28 PJD2_k127_2089214_2 279238.Saro_0089 1.316e-192 604.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,2K13Q@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA PJD2_k127_2089214_6 1144307.PMI04_03873 3.328e-47 178.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria,2KDD3@204457|Sphingomonadales 204457|Sphingomonadales E COG1505 Serine proteases of the peptidase family S9A - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N PJD2_k127_2089214_1 1144307.PMI04_03873 7.178e-203 641.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria,2KDD3@204457|Sphingomonadales 204457|Sphingomonadales E COG1505 Serine proteases of the peptidase family S9A - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N PJD2_k127_2130628_9 161528.ED21_31359 1.627e-107 351.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,2K1G6@204457|Sphingomonadales 204457|Sphingomonadales K RNA polymerase sigma rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 PJD2_k127_2130628_5 291985.CCSI01000003_gene130 1.13e-146 470.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,2K1VU@204457|Sphingomonadales 204457|Sphingomonadales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 PJD2_k127_2130628_17 161528.ED21_31349 2.295e-46 170.0 COG1310@1|root,COG1310@2|Bacteria,1NC23@1224|Proteobacteria,2UGM4@28211|Alphaproteobacteria,2K62I@204457|Sphingomonadales 204457|Sphingomonadales L metal-dependent protease of the PAD1 JAB1 superfamily - - - - - - - - - - - - Prok-JAB PJD2_k127_2130628_13 314225.ELI_01190 2.195e-93 312.0 COG5385@1|root,COG5385@2|Bacteria,1MVEY@1224|Proteobacteria,2TSE6@28211|Alphaproteobacteria,2K0H0@204457|Sphingomonadales 204457|Sphingomonadales S Histidine phosphotransferase C-terminal domain - - - ko:K13588 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001 - - - HPTransfase PJD2_k127_2130628_7 291985.CCSI01000003_gene127 4.016e-125 406.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2TSW3@28211|Alphaproteobacteria,2K0W6@204457|Sphingomonadales 204457|Sphingomonadales V N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 PJD2_k127_2130628_0 1174684.EBMC1_12396 0.0 1091.0 COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,2U2MN@28211|Alphaproteobacteria,2K2I5@204457|Sphingomonadales 204457|Sphingomonadales E Peptidase S46 - - - - - - - - - - - - Peptidase_S46 PJD2_k127_2130628_12 685035.ADAE01000018_gene1183 4.354e-95 319.0 COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,2U7N2@28211|Alphaproteobacteria,2K1WW@204457|Sphingomonadales 204457|Sphingomonadales T COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos PJD2_k127_2130628_11 161528.ED21_31309 1.858e-95 321.0 2C5U9@1|root,2Z9NJ@2|Bacteria,1RG51@1224|Proteobacteria,2U7E6@28211|Alphaproteobacteria,2KC9P@204457|Sphingomonadales 204457|Sphingomonadales S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp PJD2_k127_2130628_10 314225.ELI_01230 1.526e-97 323.0 COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,2U5D2@28211|Alphaproteobacteria,2K0TS@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF541) - - - ko:K09797 - - - - ko00000 - - - SIMPL PJD2_k127_2130628_14 383381.EH30_01330 1.271e-83 281.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2K4E9@204457|Sphingomonadales 204457|Sphingomonadales E COG0346 Lactoylglutathione lyase and related lyases gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase PJD2_k127_2130628_4 161528.ED21_31299 7.001e-167 535.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,2K097@204457|Sphingomonadales 204457|Sphingomonadales P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 PJD2_k127_2130628_3 1219035.NT2_05_03180 2.981e-175 561.0 COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,2TS4P@28211|Alphaproteobacteria,2K0A7@204457|Sphingomonadales 204457|Sphingomonadales M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - ko:K11740 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_2_3 PJD2_k127_2130628_15 1248917.ANFX01000007_gene7 5.318e-52 200.0 2AKVH@1|root,31BNP@2|Bacteria,1N2QY@1224|Proteobacteria,2UDTI@28211|Alphaproteobacteria,2K5N4@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2130628_6 685035.ADAE01000018_gene1179 5.816e-138 450.0 COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2TRIC@28211|Alphaproteobacteria,2K1QQ@204457|Sphingomonadales 204457|Sphingomonadales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE PJD2_k127_2130628_8 1219035.NT2_05_03210 4.962e-108 356.0 2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,2TQWW@28211|Alphaproteobacteria,2JZXR@204457|Sphingomonadales 204457|Sphingomonadales S Putative transmembrane protein (Alph_Pro_TM) - - - - - - - - - - - - Alph_Pro_TM PJD2_k127_2130628_1 314225.ELI_01275 3.409e-318 980.0 COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,2TUN9@28211|Alphaproteobacteria,2K091@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function DUF87 - - - ko:K06915 - - - - ko00000 - - - DUF853,DUF87 PJD2_k127_2130628_2 279238.Saro_2639 5.713e-196 627.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2U34G@28211|Alphaproteobacteria,2K0GZ@204457|Sphingomonadales 204457|Sphingomonadales V Na -driven multidrug efflux pump - - - - - - - - - - - - MatE PJD2_k127_2130628_16 1248917.ANFX01000007_gene3 2.329e-50 180.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,2K21H@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM PJD2_k127_2216778_0 1174684.EBMC1_02275 2.397e-215 685.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U0J1@28211|Alphaproteobacteria,2K2U9@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_2216778_1 402881.Plav_0088 1.837e-45 172.0 COG1309@1|root,COG1309@2|Bacteria,1MX0H@1224|Proteobacteria,2U08M@28211|Alphaproteobacteria 28211|Alphaproteobacteria K tetR family MA20_06745 - - - - - - - - - - - TetR_C_9,TetR_N PJD2_k127_222614_0 383381.EH30_00875 0.0 1514.0 COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,2K0JK@204457|Sphingomonadales 204457|Sphingomonadales E 5-methyltetrahydrofolate--homocysteine methyltransferase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind PJD2_k127_222614_1 517722.AEUE01000001_gene2717 2.585e-24 104.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,2K1GI@204457|Sphingomonadales 204457|Sphingomonadales E Glycine cleavage system T protein gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C PJD2_k127_2227390_6 685778.AORL01000021_gene396 5.207e-10 62.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,2K0Z1@204457|Sphingomonadales 204457|Sphingomonadales NT chemotaxis protein cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt PJD2_k127_2227390_5 291985.CCSI01000003_gene216 3.509e-34 139.0 COG0835@1|root,COG0835@2|Bacteria,1N88R@1224|Proteobacteria,2UGI7@28211|Alphaproteobacteria,2K55G@204457|Sphingomonadales 204457|Sphingomonadales NT Two component signalling adaptor domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW PJD2_k127_2227390_3 237727.NAP1_15873 9.552e-66 226.0 COG2199@1|root,COG3706@2|Bacteria,1RH2K@1224|Proteobacteria,2U9EP@28211|Alphaproteobacteria,2K4IT@204457|Sphingomonadales 204457|Sphingomonadales T chemotaxis cheY - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg PJD2_k127_2227390_1 1479239.JQMU01000001_gene1891 5.892e-110 367.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2TSGV@28211|Alphaproteobacteria,2K0GS@204457|Sphingomonadales 204457|Sphingomonadales NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg PJD2_k127_2227390_2 291985.CCSI01000003_gene219 2.966e-100 334.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2TRQ3@28211|Alphaproteobacteria,2K3X1@204457|Sphingomonadales 204457|Sphingomonadales NT COG1352 Methylase of chemotaxis methyl-accepting proteins cheR - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR PJD2_k127_2227390_0 161528.ED21_22133 1.475e-195 625.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TS9V@28211|Alphaproteobacteria,2K1VI@204457|Sphingomonadales 204457|Sphingomonadales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - CHASE4,EAL,GGDEF PJD2_k127_2227390_4 161528.ED21_22123 6.258e-37 154.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K1AE@204457|Sphingomonadales 204457|Sphingomonadales NT chemotaxis - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,Protoglobin PJD2_k127_2246491_1 1449076.JOOE01000004_gene382 2.709e-44 163.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TVIE@28211|Alphaproteobacteria,2K9PM@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_2246491_2 460265.Mnod_0143 4.336e-23 103.0 COG0784@1|root,COG0784@2|Bacteria,1RG15@1224|Proteobacteria,2U7Z6@28211|Alphaproteobacteria,1JWA2@119045|Methylobacteriaceae 28211|Alphaproteobacteria T PFAM response regulator receiver - - - - - - - - - - - - DUF2934,Response_reg PJD2_k127_2246491_0 1219035.NT2_03_00240 3.372e-266 833.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TST2@28211|Alphaproteobacteria,2K189@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C PJD2_k127_2253827_4 158500.BV97_00168 2.997e-98 333.0 COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,2TUCN@28211|Alphaproteobacteria,2K0QD@204457|Sphingomonadales 204457|Sphingomonadales V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 PJD2_k127_2253827_1 317655.Sala_2771 8.405e-263 815.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,2K25I@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.3,1.4.1.4 ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N PJD2_k127_2253827_0 702113.PP1Y_AT6562 5.501e-280 892.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2TS2A@28211|Alphaproteobacteria,2KCX4@204457|Sphingomonadales 204457|Sphingomonadales S CHAT domain - - - - - - - - - - - - CHAT PJD2_k127_2253827_2 1479239.JQMU01000001_gene2199 1.347e-256 807.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,2K1MH@204457|Sphingomonadales 204457|Sphingomonadales T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc PJD2_k127_2253827_6 1088721.NSU_1234 3.566e-59 213.0 2ENSP@1|root,33GDV@2|Bacteria,1N3J8@1224|Proteobacteria,2UBZE@28211|Alphaproteobacteria,2K5KK@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2253827_3 702113.PP1Y_AT6521 6.697e-172 557.0 COG2831@1|root,COG2831@2|Bacteria,1R6KX@1224|Proteobacteria,2TUEN@28211|Alphaproteobacteria,2K29V@204457|Sphingomonadales 204457|Sphingomonadales U COG2831 Hemolysin activation secretion protein - - - - - - - - - - - - POTRA_2,ShlB PJD2_k127_2253827_5 1088721.NSU_1236 9.939e-61 233.0 COG3210@1|root,COG3210@2|Bacteria,1R8TG@1224|Proteobacteria,2U41V@28211|Alphaproteobacteria,2K1DN@204457|Sphingomonadales 204457|Sphingomonadales U COG3210 Large exoproteins involved in heme utilization or adhesion - - - - - - - - - - - - Haemagg_act PJD2_k127_2262470_2 383381.EH30_05640 2.94e-66 228.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,2JZX4@204457|Sphingomonadales 204457|Sphingomonadales F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS PJD2_k127_2262470_1 1219035.NT2_06_02870 2.345e-80 272.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,2K439@204457|Sphingomonadales 204457|Sphingomonadales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N PJD2_k127_2262470_7 1248917.ANFX01000008_gene334 3.711e-17 86.0 2AM3M@1|root,32HWE@2|Bacteria,1P5E2@1224|Proteobacteria,2UXKP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_2262470_4 702113.PP1Y_AT24944 1.048e-29 121.0 COG0483@1|root,COG0483@2|Bacteria,1N7D7@1224|Proteobacteria,2UF6T@28211|Alphaproteobacteria,2K5WG@204457|Sphingomonadales 204457|Sphingomonadales G Domain of unknown function (DUF4170) - - - - - - - - - - - - DUF4170 PJD2_k127_2262470_8 161528.ED21_27093 3.999e-15 82.0 2A33G@1|root,31D50@2|Bacteria,1P3B1@1224|Proteobacteria,2UU7M@28211|Alphaproteobacteria,2KBGI@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2262470_5 291985.CCSI01000001_gene2226 2.872e-26 117.0 2A9PK@1|root,30YWH@2|Bacteria,1P5WS@1224|Proteobacteria,2UWXG@28211|Alphaproteobacteria,2K8B1@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2262470_6 517722.AEUE01000006_gene1899 2.648e-19 95.0 2AMA1@1|root,31C4Y@2|Bacteria,1P0IT@1224|Proteobacteria,2UVQS@28211|Alphaproteobacteria,2K7A5@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - Phage_holin_3_6 PJD2_k127_2262470_3 1479239.JQMU01000001_gene2652 5.668e-53 195.0 2EJM3@1|root,33DC0@2|Bacteria,1NCX3@1224|Proteobacteria,2UFXE@28211|Alphaproteobacteria,2K6CI@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2262470_0 279238.Saro_2223 3.353e-229 713.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,2K00W@204457|Sphingomonadales 204457|Sphingomonadales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N PJD2_k127_2307244_0 1248760.ANFZ01000006_gene2596 1.582e-255 791.0 COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,2TU7I@28211|Alphaproteobacteria,2K14D@204457|Sphingomonadales 204457|Sphingomonadales H Thi4 family - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 PJD2_k127_2307244_2 314225.ELI_12460 2.08e-46 171.0 COG2246@1|root,COG2246@2|Bacteria,1N1WS@1224|Proteobacteria,2UDTY@28211|Alphaproteobacteria,2K662@204457|Sphingomonadales 204457|Sphingomonadales S GtrA-like protein - - - - - - - - - - - - GtrA PJD2_k127_2307244_1 237727.NAP1_13663 1.179e-162 536.0 COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,2TV2J@28211|Alphaproteobacteria,2KDNP@204457|Sphingomonadales 204457|Sphingomonadales S oligosaccharyl transferase activity - - - - - - - - - - - - - PJD2_k127_233020_4 1479239.JQMU01000001_gene2601 4.943e-19 88.0 2AKK9@1|root,31BCH@2|Bacteria,1Q771@1224|Proteobacteria,2VDBG@28211|Alphaproteobacteria,2K8ID@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_233020_3 291985.CCSI01000001_gene2647 4.201e-56 202.0 2A22K@1|root,30QCN@2|Bacteria,1NZ4F@1224|Proteobacteria,2UYZ4@28211|Alphaproteobacteria,2KA9D@204457|Sphingomonadales 204457|Sphingomonadales S A nuclease family of the HNH/ENDO VII superfamily with conserved AHH - - - - - - - - - - - - AHH PJD2_k127_233020_1 517722.AEUE01000006_gene1940 2.764e-172 545.0 COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2TS5U@28211|Alphaproteobacteria,2K0V5@204457|Sphingomonadales 204457|Sphingomonadales S 2-nitropropane dioxygenase - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO PJD2_k127_233020_0 517722.AEUE01000006_gene1939 4.917e-181 572.0 COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,2TRU9@28211|Alphaproteobacteria,2KD7H@204457|Sphingomonadales 204457|Sphingomonadales S amidohydrolase - - - - - - - - - - - - Amidohydro_2 PJD2_k127_233020_2 1479239.JQMU01000001_gene2606 1.441e-122 396.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,2K1S1@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer PJD2_k127_2343035_1 685035.ADAE01000020_gene1440 3.62e-90 322.0 COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TUVB@28211|Alphaproteobacteria,2K24U@204457|Sphingomonadales 204457|Sphingomonadales I Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_2343035_0 685035.ADAE01000020_gene1442 1.131e-191 610.0 COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2TVI8@28211|Alphaproteobacteria,2KD26@204457|Sphingomonadales 204457|Sphingomonadales G MFS/sugar transport protein - - - - - - - - - - - - MFS_2 PJD2_k127_2423494_16 158500.BV97_03178 4.835e-29 124.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2K1NQ@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09919 - - - - ko00000 - - - FemAB_like PJD2_k127_2423494_4 1219035.NT2_05_00350 5.964e-95 318.0 COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2TV1D@28211|Alphaproteobacteria,2K3TX@204457|Sphingomonadales 204457|Sphingomonadales C glycerophosphoryl diester phosphodiesterase - - - - - - - - - - - - GDPD PJD2_k127_2423494_9 314225.ELI_14100 3.224e-58 217.0 COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,2K4U7@204457|Sphingomonadales 204457|Sphingomonadales J endoribonuclease - - - - - - - - - - - - YjgF_endoribonc PJD2_k127_2423494_6 1248917.ANFX01000019_gene2308 8.624e-91 308.0 COG0647@1|root,COG0647@2|Bacteria,1RBCP@1224|Proteobacteria,2U6MG@28211|Alphaproteobacteria,2KDJX@204457|Sphingomonadales 204457|Sphingomonadales G UMP catabolic process - - - - - - - - - - - - - PJD2_k127_2423494_15 517722.AEUE01000002_gene2218 2.181e-29 121.0 2DMKE@1|root,32S6E@2|Bacteria,1NH3D@1224|Proteobacteria,2UHAS@28211|Alphaproteobacteria,2K72S@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF3572) - - - - - - - - - - - - DUF3572 PJD2_k127_2423494_10 383381.EH30_12325 3.336e-52 187.0 COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria,2K53C@204457|Sphingomonadales 204457|Sphingomonadales T response regulator - - - ko:K11443 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg PJD2_k127_2423494_11 279238.Saro_3109 5.516e-52 198.0 COG4339@1|root,COG4339@2|Bacteria,1QV5J@1224|Proteobacteria,2TWA1@28211|Alphaproteobacteria,2KEDA@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - - - - - - - - - - - PJD2_k127_2423494_17 1479239.JQMU01000001_gene1289 2.597e-25 121.0 COG0236@1|root,COG0236@2|Bacteria,1NHQD@1224|Proteobacteria,2UGSG@28211|Alphaproteobacteria,2K5YB@204457|Sphingomonadales 204457|Sphingomonadales IQ acyl carrier protein - - - - - - - - - - - - PP-binding PJD2_k127_2423494_18 517722.AEUE01000002_gene2215 5.588e-12 72.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQYP@28211|Alphaproteobacteria,2K0V8@204457|Sphingomonadales 204457|Sphingomonadales E COG0156 7-keto-8-aminopelargonate synthetase and related enzymes - - 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 PJD2_k127_2423494_0 517722.AEUE01000002_gene2215 7.647e-220 683.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQYP@28211|Alphaproteobacteria,2K0V8@204457|Sphingomonadales 204457|Sphingomonadales E COG0156 7-keto-8-aminopelargonate synthetase and related enzymes - - 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 PJD2_k127_2423494_2 1123267.JONN01000001_gene1203 1.612e-115 392.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,2K2YU@204457|Sphingomonadales 204457|Sphingomonadales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_8 PJD2_k127_2423494_8 1219035.NT2_05_00250 1.226e-59 210.0 COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2U768@28211|Alphaproteobacteria,2K4NB@204457|Sphingomonadales 204457|Sphingomonadales O redox protein, regulator of disulfide bond formation osmC - - ko:K04063 - - - - ko00000 - - - OsmC PJD2_k127_2423494_12 861299.J421_0558 9.918e-46 182.0 COG0793@1|root,COG0793@2|Bacteria,1ZV0G@142182|Gemmatimonadetes 142182|Gemmatimonadetes M N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - - - - - - - - - - Peptidase_S41,Peptidase_S41_N PJD2_k127_2423494_14 1248916.ANFY01000007_gene2220 2.595e-36 143.0 COG1522@1|root,COG1522@2|Bacteria,1NESY@1224|Proteobacteria,2UGP7@28211|Alphaproteobacteria,2K76T@204457|Sphingomonadales 204457|Sphingomonadales K AsnC-type helix-turn-helix domain - - - - - - - - - - - - AsnC_trans_reg,HTH_AsnC-type PJD2_k127_2423494_1 685035.ADAE01000023_gene1747 2.223e-158 503.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2K06J@204457|Sphingomonadales 204457|Sphingomonadales S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B PJD2_k127_2423494_13 1219049.SP5_073_00310 5.243e-40 150.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,2K5QB@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K22042 - - - - ko00000,ko03000 - - - HTH_5 PJD2_k127_2423494_7 517722.AEUE01000002_gene2211 1.369e-65 233.0 COG0607@1|root,COG0607@2|Bacteria,1RDIR@1224|Proteobacteria,2U820@28211|Alphaproteobacteria,2K0I5@204457|Sphingomonadales 204457|Sphingomonadales P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892,Rhodanese PJD2_k127_2423494_5 1335760.ASTG01000031_gene1840 4.046e-91 307.0 COG0730@1|root,COG0730@2|Bacteria,1MVBS@1224|Proteobacteria,2TQW0@28211|Alphaproteobacteria,2JZVA@204457|Sphingomonadales 204457|Sphingomonadales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE PJD2_k127_2423494_3 279238.Saro_3116 4.767e-108 352.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2U78A@28211|Alphaproteobacteria,2K3NK@204457|Sphingomonadales 204457|Sphingomonadales S DedA family - - - - - - - - - - - - SNARE_assoc PJD2_k127_2429648_0 237727.NAP1_08332 9.627e-178 559.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria,2K0KC@204457|Sphingomonadales 204457|Sphingomonadales C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase PJD2_k127_2429648_2 291985.CCSI01000005_gene845 3.459e-135 436.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,2K042@204457|Sphingomonadales 204457|Sphingomonadales J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD PJD2_k127_2429648_3 1219035.NT2_01_01390 5.576e-133 452.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2K0HZ@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA PJD2_k127_2429648_1 1088721.NSU_0397 3.464e-173 557.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2TSJ3@28211|Alphaproteobacteria,2K0UR@204457|Sphingomonadales 204457|Sphingomonadales O peptidylprolyl isomerase surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N,SurA_N_3 PJD2_k127_2429648_4 161528.ED21_30319 2.304e-120 389.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,2K1GQ@204457|Sphingomonadales 204457|Sphingomonadales M Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C PJD2_k127_248986_8 279238.Saro_1933 1.719e-05 46.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2K0DA@204457|Sphingomonadales 204457|Sphingomonadales S MazG family mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG PJD2_k127_248986_2 314225.ELI_06255 6.684e-212 666.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria,2K0SI@204457|Sphingomonadales 204457|Sphingomonadales S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 PJD2_k127_248986_6 161528.ED21_27633 2.521e-85 286.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria,2K2YT@204457|Sphingomonadales 204457|Sphingomonadales J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq - - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq PJD2_k127_248986_1 237727.NAP1_05530 3.548e-248 772.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,2K1KM@204457|Sphingomonadales 204457|Sphingomonadales T Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_248986_0 291985.CCSI01000001_gene2354 2.56e-321 999.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,2K01N@204457|Sphingomonadales 204457|Sphingomonadales T Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation ntrY - 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 PJD2_k127_248986_3 237727.NAP1_05540 3.784e-201 639.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales 204457|Sphingomonadales T Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains ntrC - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_248986_5 383381.EH30_06195 6.234e-126 412.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,2K1YJ@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase ntrB - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 PJD2_k127_248986_4 1479239.JQMU01000001_gene2755 5.282e-178 570.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,2K0QH@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus PJD2_k127_248986_7 291985.CCSI01000001_gene2358 4.429e-44 181.0 COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2K0Y0@204457|Sphingomonadales 204457|Sphingomonadales I Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) ispDF - 2.7.7.60,4.6.1.12 ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB PJD2_k127_252268_13 1122970.AUHC01000004_gene2108 1.06e-15 76.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria,2K287@204457|Sphingomonadales 204457|Sphingomonadales S Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 PJD2_k127_252268_12 161528.ED21_23333 2.381e-25 113.0 2B20I@1|root,31UH7@2|Bacteria,1NA6V@1224|Proteobacteria,2UIZX@28211|Alphaproteobacteria,2K771@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_252268_5 685035.ADAE01000011_gene1235 1.141e-131 431.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,2K10R@204457|Sphingomonadales 204457|Sphingomonadales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 PJD2_k127_252268_7 517722.AEUE01000008_gene97 1.883e-88 295.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2U3RS@28211|Alphaproteobacteria,2K0MU@204457|Sphingomonadales 204457|Sphingomonadales H Riboflavin synthase ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding PJD2_k127_252268_8 1122970.AUHC01000013_gene1094 2.021e-71 246.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2K4E7@204457|Sphingomonadales 204457|Sphingomonadales F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase PJD2_k127_252268_2 314225.ELI_10530 1.318e-228 721.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2TRN1@28211|Alphaproteobacteria,2K0N6@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein PJD2_k127_252268_9 314225.ELI_10535 6.667e-41 155.0 2C0YA@1|root,3437Q@2|Bacteria,1NIVD@1224|Proteobacteria,2UKNB@28211|Alphaproteobacteria,2K7X3@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - DUF4345 PJD2_k127_252268_1 314225.ELI_10545 3.465e-269 835.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria,2K1BA@204457|Sphingomonadales 204457|Sphingomonadales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 PJD2_k127_252268_3 1219035.NT2_05_01110 7.009e-135 432.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,2K080@204457|Sphingomonadales 204457|Sphingomonadales H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran PJD2_k127_252268_4 314225.ELI_10555 1.838e-134 432.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,2K2A5@204457|Sphingomonadales 204457|Sphingomonadales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS PJD2_k127_252268_10 1088721.NSU_1331 6.365e-35 136.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria,2K617@204457|Sphingomonadales 204457|Sphingomonadales J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p PJD2_k127_252268_0 237727.NAP1_11123 1.346e-269 837.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,2JZZ0@204457|Sphingomonadales 204457|Sphingomonadales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N PJD2_k127_252268_6 383381.EH30_11490 2.549e-119 389.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2TRWY@28211|Alphaproteobacteria,2K1F9@204457|Sphingomonadales 204457|Sphingomonadales H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF PJD2_k127_2530498_11 1123267.JONN01000001_gene939 2.549e-16 83.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 PJD2_k127_2530498_0 517722.AEUE01000004_gene1196 2.613e-181 572.0 COG3829@1|root,COG3829@2|Bacteria,1QUPP@1224|Proteobacteria,2TR58@28211|Alphaproteobacteria,2K0CK@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain pspF - - ko:K03974 - - - - ko00000,ko03000 - - - HTH_8,Sigma54_activat PJD2_k127_2530498_1 314225.ELI_03395 5.637e-120 396.0 COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,2U6CN@28211|Alphaproteobacteria,2K2DP@204457|Sphingomonadales 204457|Sphingomonadales KT Phage shock protein A pspA - - ko:K03969 - - - - ko00000 - - - PspA_IM30 PJD2_k127_2530498_6 161528.ED21_23891 8.956e-38 143.0 2EH78@1|root,33AZ2@2|Bacteria,1N7AP@1224|Proteobacteria,2UGJI@28211|Alphaproteobacteria,2K6SQ@204457|Sphingomonadales 204457|Sphingomonadales S Phage shock protein B pspB - - ko:K03970 - - - - ko00000,ko02048 - - - PspB PJD2_k127_2530498_5 314225.ELI_03385 5.004e-62 218.0 COG1983@1|root,COG1983@2|Bacteria,1RHXA@1224|Proteobacteria,2UA9Z@28211|Alphaproteobacteria,2K54F@204457|Sphingomonadales 204457|Sphingomonadales KT PspC domain pspC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC PJD2_k127_2530498_7 314225.ELI_03375 7.81e-33 134.0 29QFW@1|root,30BF9@2|Bacteria,1NNM7@1224|Proteobacteria,2UM5Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_2530498_8 314225.ELI_03365 8.425e-27 118.0 28X1J@1|root,30MES@2|Bacteria,1MZB2@1224|Proteobacteria,2UCMI@28211|Alphaproteobacteria,2KDNT@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2530498_14 1479239.JQMU01000001_gene2085 3.854e-08 63.0 2APSZ@1|root,31EX3@2|Bacteria,1P6QC@1224|Proteobacteria,2UYJB@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_2530498_10 161528.ED21_23861 1.837e-20 96.0 29B0T@1|root,2ZXZQ@2|Bacteria,1ND25@1224|Proteobacteria,2UJ2J@28211|Alphaproteobacteria,2K6SU@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2530498_9 685035.ADAE01000018_gene360 2.013e-21 96.0 2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria,2UGT0@28211|Alphaproteobacteria,2K7V2@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2530498_4 161528.ED21_23851 8.131e-67 229.0 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,2K4H9@204457|Sphingomonadales 204457|Sphingomonadales S SufE protein probably involved in Fe-S center assembly sufE - - ko:K02426 - - - - ko00000 - - - SufE PJD2_k127_2530498_2 279238.Saro_1168 4.287e-94 310.0 COG3000@1|root,COG3000@2|Bacteria,1RJ68@1224|Proteobacteria,2U9CS@28211|Alphaproteobacteria,2K3D1@204457|Sphingomonadales 204457|Sphingomonadales I hydroxylase - - 1.14.15.24 ko:K15746 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00372 R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747 RC00478,RC00704,RC02629 ko00000,ko00001,ko00002,ko01000 - - - FA_hydroxylase PJD2_k127_2530498_15 1088721.NSU_2748 9.714e-06 56.0 2EE3J@1|root,337Y5@2|Bacteria,1NC5N@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - PJD2_k127_2530498_3 383381.EH30_09505 3.34e-69 236.0 COG0824@1|root,COG0824@2|Bacteria,1RHB1@1224|Proteobacteria,2UATC@28211|Alphaproteobacteria,2K4SF@204457|Sphingomonadales 204457|Sphingomonadales S thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,Acyl-ACP_TE PJD2_k127_2539317_0 768671.ThimaDRAFT_0180 4.965e-99 330.0 COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,1RNMT@1236|Gammaproteobacteria,1WXIM@135613|Chromatiales 135613|Chromatiales P PFAM Ion transport - - - ko:K08714 - - - - ko00000,ko02000 1.A.1.14 - - Ion_trans PJD2_k127_2539317_1 1297863.APJF01000020_gene2913 3.78e-89 310.0 COG0604@1|root,COG0604@2|Bacteria,1MXCV@1224|Proteobacteria,2TTE7@28211|Alphaproteobacteria,3JVQ8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N PJD2_k127_2539317_3 1121861.KB899914_gene2088 1.654e-08 61.0 COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2TT57@28211|Alphaproteobacteria 28211|Alphaproteobacteria S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C PJD2_k127_2539317_2 1121861.KB899926_gene2599 6.72e-21 94.0 COG0477@1|root,COG2814@2|Bacteria,1P3S4@1224|Proteobacteria,2TVAQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 PJD2_k127_2546918_6 1479239.JQMU01000001_gene484 8.972e-61 213.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,2K0DP@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the universal ribosomal protein uS2 family rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 PJD2_k127_2546918_4 383381.EH30_03515 1.874e-114 377.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,2K1B9@204457|Sphingomonadales 204457|Sphingomonadales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_tran_2,CDP-OH_P_transf PJD2_k127_2546918_3 279238.Saro_1366 6.628e-127 409.0 COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2TRMG@28211|Alphaproteobacteria,2K019@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase PJD2_k127_2546918_1 1479239.JQMU01000001_gene487 7.31e-201 629.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TU94@28211|Alphaproteobacteria,2K2VX@204457|Sphingomonadales 204457|Sphingomonadales I COG0332 3-oxoacyl- acyl-carrier-protein synthase III - - 2.3.1.207 ko:K16872 - - - - ko00000,ko01000 - - - ACP_syn_III,ACP_syn_III_C PJD2_k127_2546918_2 314225.ELI_03705 1.477e-130 429.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria,2K163@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family - - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind PJD2_k127_2546918_5 291985.CCSI01000001_gene1916 9.316e-77 273.0 2D5TK@1|root,32TJS@2|Bacteria,1RGDJ@1224|Proteobacteria,2U915@28211|Alphaproteobacteria,2K4I8@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2546918_9 1144305.PMI02_00529 4.583e-36 151.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria,2K5WD@204457|Sphingomonadales 204457|Sphingomonadales L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions - - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding PJD2_k127_2546918_0 1248916.ANFY01000005_gene2768 0.0 1108.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,2K15B@204457|Sphingomonadales 204457|Sphingomonadales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C PJD2_k127_2546918_10 864073.HFRIS_013489 2.955e-11 70.0 COG5430@1|root,COG5430@2|Bacteria,1MZNQ@1224|Proteobacteria,2VX7C@28216|Betaproteobacteria,4750P@75682|Oxalobacteraceae 28216|Betaproteobacteria S Signal peptide protein - - - - - - - - - - - - SCPU PJD2_k127_2546918_7 314225.ELI_03685 1.617e-50 182.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria,2K5JW@204457|Sphingomonadales 204457|Sphingomonadales S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd PJD2_k127_2546918_8 1144305.PMI02_04475 6.381e-41 157.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,2K0MV@204457|Sphingomonadales 204457|Sphingomonadales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646 PJD2_k127_2548744_0 279238.Saro_3215 0.0 1376.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,2K0Q0@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 PJD2_k127_2548744_7 161528.ED21_18617 5.455e-61 214.0 COG5468@1|root,COG5468@2|Bacteria,1RKF8@1224|Proteobacteria,2UACI@28211|Alphaproteobacteria,2K4FJ@204457|Sphingomonadales 204457|Sphingomonadales S Lipopolysaccharide-assembly - - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE PJD2_k127_2548744_2 1219035.NT2_04_01540 1.309e-135 439.0 COG1466@1|root,COG1466@2|Bacteria,1N7AB@1224|Proteobacteria,2UHPM@28211|Alphaproteobacteria,2K0ER@204457|Sphingomonadales 204457|Sphingomonadales L DNA polymerase III holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta PJD2_k127_2548744_1 314225.ELI_12255 3.64e-143 469.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2TRZA@28211|Alphaproteobacteria,2K10K@204457|Sphingomonadales 204457|Sphingomonadales M sugar transferase spsB - - ko:K20997 ko02025,map02025 - - - ko00000,ko00001 - - - Bac_transf PJD2_k127_2548744_6 291985.CCSI01000002_gene1599 1.289e-75 259.0 COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,2K3YP@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - OstA PJD2_k127_2548744_5 291985.CCSI01000002_gene1600 1.167e-91 308.0 COG5375@1|root,COG5375@2|Bacteria,1NMV8@1224|Proteobacteria,2VCS4@28211|Alphaproteobacteria,2K34V@204457|Sphingomonadales 204457|Sphingomonadales S Protein conserved in bacteria - - - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC PJD2_k127_2548744_3 237727.NAP1_13918 2.713e-105 344.0 COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,2K0FG@204457|Sphingomonadales 204457|Sphingomonadales L 3'-5' exonuclease - - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1 PJD2_k127_2548744_4 161528.ED21_18592 8.073e-104 358.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,2U1VI@28211|Alphaproteobacteria,2K0CQ@204457|Sphingomonadales 204457|Sphingomonadales L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung - 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG PJD2_k127_2568497_13 314225.ELI_12025 3.632e-47 185.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2K093@204457|Sphingomonadales 204457|Sphingomonadales I acyl-CoA dehydrogenase - - - ko:K06446 ko00930,ko01100,ko01120,map00930,map01100,map01120 - R06943 RC00052 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_2568497_17 314225.ELI_12020 1.109e-12 71.0 2A8ZE@1|root,30Y39@2|Bacteria,1P5JS@1224|Proteobacteria,2UX96@28211|Alphaproteobacteria,2KBJA@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2568497_0 291985.CCSI01000002_gene1723 1.134e-294 922.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2TS8B@28211|Alphaproteobacteria,2K0QS@204457|Sphingomonadales 204457|Sphingomonadales L DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind PJD2_k127_2568497_6 314225.ELI_11990 4.58e-139 454.0 COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria,2U3Y9@28211|Alphaproteobacteria,2K0EA@204457|Sphingomonadales 204457|Sphingomonadales P alginic acid biosynthetic process - - - - - - - - - - - - Beta_helix PJD2_k127_2568497_15 1247963.JPHU01000020_gene2972 1.457e-40 151.0 COG1734@1|root,COG1734@2|Bacteria,1MZIB@1224|Proteobacteria,2UCQA@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG1734 DnaK suppressor protein - - - - - - - - - - - - zf-dskA_traR PJD2_k127_2568497_14 1219035.NT2_04_01250 1.029e-45 184.0 COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,2UA4N@28211|Alphaproteobacteria,2K5NF@204457|Sphingomonadales 204457|Sphingomonadales S Acetyltransferase (GNAT) domain - - - ko:K03824 - - - - ko00000,ko01000 - - - Acetyltransf_9 PJD2_k127_2568497_4 1219035.NT2_04_01240 3.94e-160 520.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,2TR82@28211|Alphaproteobacteria,2K0DD@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA - 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 PJD2_k127_2568497_5 1088721.NSU_2483 5.821e-143 459.0 COG0708@1|root,COG0708@2|Bacteria,1MVMC@1224|Proteobacteria,2TRWQ@28211|Alphaproteobacteria,2K09T@204457|Sphingomonadales 204457|Sphingomonadales L exodeoxyribonuclease III - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos PJD2_k127_2568497_9 161528.ED21_18052 5.149e-88 301.0 COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria,2K43J@204457|Sphingomonadales 204457|Sphingomonadales M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - - - - - - - - - - LolA PJD2_k127_2568497_16 1088721.NSU_2481 4.816e-24 106.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria,2K6VC@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 PJD2_k127_2568497_12 1122612.AUBA01000007_gene1115 1.399e-49 181.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,2K5BU@204457|Sphingomonadales 204457|Sphingomonadales J chain release factor - - - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 PJD2_k127_2568497_7 702113.PP1Y_AT35400 1.487e-100 337.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2TSCG@28211|Alphaproteobacteria,2K0XZ@204457|Sphingomonadales 204457|Sphingomonadales J Pseudouridine synthase - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 PJD2_k127_2568497_1 291985.CCSI01000002_gene1711 7.648e-266 831.0 COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TUBY@28211|Alphaproteobacteria,2K1FB@204457|Sphingomonadales 204457|Sphingomonadales EH component I pabB - 2.6.1.85,4.1.3.38 ko:K01665,ko:K03342 ko00790,map00790 - R01716,R05553 RC00010,RC01418,RC01843,RC02148 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4,Anth_synt_I_N,Chorismate_bind PJD2_k127_2568497_2 237727.NAP1_14143 1.24e-256 799.0 COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria,2JZYW@204457|Sphingomonadales 204457|Sphingomonadales S Bacterial protein of unknown function (DUF853) - - - ko:K06915 - - - - ko00000 - - - DUF853 PJD2_k127_2568497_10 685035.ADAE01000023_gene1705 5.974e-86 287.0 COG3576@1|root,COG3576@2|Bacteria,1R8RC@1224|Proteobacteria,2TUXH@28211|Alphaproteobacteria,2K323@204457|Sphingomonadales 204457|Sphingomonadales S Pfam:Pyridox_oxidase - - - - - - - - - - - - Putative_PNPOx PJD2_k127_2568497_8 1219035.NT2_04_04610 3.318e-89 302.0 COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2U1MH@28211|Alphaproteobacteria,2K0EG@204457|Sphingomonadales 204457|Sphingomonadales L endonuclease - - - - - - - - - - - - Exo_endo_phos PJD2_k127_2568497_11 291985.CCSI01000002_gene1291 1.73e-57 201.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U952@28211|Alphaproteobacteria,2K4EF@204457|Sphingomonadales 204457|Sphingomonadales K Belongs to the P(II) protein family - - - ko:K04752 - - - - ko00000 - - - P-II PJD2_k127_2568497_3 1088721.NSU_1934 3.064e-224 708.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,2K0PX@204457|Sphingomonadales 204457|Sphingomonadales P Ammonium Transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp PJD2_k127_2572546_7 279238.Saro_2259 1.313e-30 122.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2TSEU@28211|Alphaproteobacteria,2K069@204457|Sphingomonadales 204457|Sphingomonadales E phosphoserine phosphatase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD PJD2_k127_2572546_3 161528.ED21_28908 2.106e-123 401.0 COG5031@1|root,COG5031@2|Bacteria,1RGXT@1224|Proteobacteria,2U0IY@28211|Alphaproteobacteria,2KCGW@204457|Sphingomonadales 204457|Sphingomonadales H Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - ko:K18586 - - - - ko00000 - - - Coq4 PJD2_k127_2572546_0 1219035.NT2_06_03090 0.0 1191.0 COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2K25A@204457|Sphingomonadales 204457|Sphingomonadales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C PJD2_k127_2572546_6 1219035.NT2_06_03080 7.544e-33 129.0 COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,2K6WZ@204457|Sphingomonadales 204457|Sphingomonadales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S PJD2_k127_2572546_2 383381.EH30_05495 8.722e-136 441.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,2K19H@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10 ko:K00795 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364 R01658,R02003 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt PJD2_k127_2572546_5 1112214.AHIS01000061_gene2829 1.877e-74 255.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2U74H@28211|Alphaproteobacteria,2K1RJ@204457|Sphingomonadales 204457|Sphingomonadales H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like PJD2_k127_2572546_4 314225.ELI_05585 4.621e-90 302.0 COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,2U5RN@28211|Alphaproteobacteria,2K3Z3@204457|Sphingomonadales 204457|Sphingomonadales M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - Pro_isomerase PJD2_k127_2572546_1 1088721.NSU_0052 6.906e-165 522.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2TS0D@28211|Alphaproteobacteria,2K0G0@204457|Sphingomonadales 204457|Sphingomonadales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth PJD2_k127_2583329_1 1219035.NT2_02_01360 1.001e-115 376.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,2K1NH@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 PJD2_k127_2583329_2 685035.ADAE01000002_gene2541 1.311e-79 276.0 2DPYS@1|root,33403@2|Bacteria,1N637@1224|Proteobacteria,2UEN9@28211|Alphaproteobacteria,2K6J2@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2583329_0 383381.EH30_08340 2.892e-172 545.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,2K21F@204457|Sphingomonadales 204457|Sphingomonadales T Phosphate starvation-inducible protein PhoH - - - ko:K06217 - - - - ko00000 - - - PhoH PJD2_k127_2583329_3 1096930.L284_10375 4.8e-62 217.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,2K4EE@204457|Sphingomonadales 204457|Sphingomonadales J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 PJD2_k127_2583329_4 291985.CCSI01000005_gene921 1.259e-55 198.0 COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,2K03F@204457|Sphingomonadales 204457|Sphingomonadales S COG1253 Hemolysins and related proteins containing CBS domains - - - - - - - - - - - - CBS,CorC_HlyC PJD2_k127_2599975_0 279238.Saro_1746 0.0 1009.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,2K1NE@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C PJD2_k127_2599975_1 685035.ADAE01000024_gene1810 2.299e-108 373.0 28VPU@1|root,2ZHRS@2|Bacteria,1R7QU@1224|Proteobacteria,2U49X@28211|Alphaproteobacteria,2K3S8@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2599975_2 1449076.JOOE01000004_gene166 1.648e-27 119.0 2E3VP@1|root,32YSV@2|Bacteria,1RFZF@1224|Proteobacteria,2UFT8@28211|Alphaproteobacteria,2K6F4@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2600341_0 685035.ADAE01000018_gene633 0.0 1033.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K02W@204457|Sphingomonadales 28211|Alphaproteobacteria O peptidase M13 - - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N PJD2_k127_2600341_1 517722.AEUE01000006_gene1897 2.257e-24 102.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,2K00W@204457|Sphingomonadales 204457|Sphingomonadales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N PJD2_k127_2603179_4 291985.CCSI01000003_gene221 4.15e-82 279.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K1AE@204457|Sphingomonadales 204457|Sphingomonadales NT chemotaxis - - - - - - - - - - - - MCPsignal,Protoglobin PJD2_k127_2603179_0 291985.CCSI01000007_gene506 0.0 1087.0 COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,2UMCM@28211|Alphaproteobacteria,2K3DW@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 PJD2_k127_2603179_1 161528.ED21_22108 2.795e-239 751.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,2TV2E@28211|Alphaproteobacteria,2JZVQ@204457|Sphingomonadales 204457|Sphingomonadales P Flavin-binding monooxygenase-like - - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_3 PJD2_k127_2603179_2 1112212.JH584235_gene3608 3.32e-124 401.0 COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,2K05Q@204457|Sphingomonadales 204457|Sphingomonadales S nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - - - - - - - - - - MoCF_biosynth PJD2_k127_2603179_3 517722.AEUE01000003_gene1283 3.439e-118 383.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2TRXP@28211|Alphaproteobacteria,2K0YM@204457|Sphingomonadales 204457|Sphingomonadales J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA - - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 PJD2_k127_2603179_5 1088721.NSU_0800 5.89e-63 217.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2U760@28211|Alphaproteobacteria,2K3Z9@204457|Sphingomonadales 204457|Sphingomonadales J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK - - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N PJD2_k127_2614132_2 237727.NAP1_10683 4.285e-233 756.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,2K0U9@204457|Sphingomonadales 204457|Sphingomonadales I poly(R)-hydroxyalkanoic acid synthase phaC - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N PJD2_k127_2614132_1 1449076.JOOE01000003_gene3136 1.265e-241 750.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TRE3@28211|Alphaproteobacteria,2K0GY@204457|Sphingomonadales 204457|Sphingomonadales E Aminotransferase - - - ko:K14261 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 PJD2_k127_2614132_8 314225.ELI_10165 4.407e-49 187.0 COG2197@1|root,COG2197@2|Bacteria,1NNTV@1224|Proteobacteria,2UN2N@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT response regulator - - - - - - - - - - - - GerE PJD2_k127_2614132_11 1502850.FG91_02264 1.055e-28 121.0 2EP5S@1|root,33GSG@2|Bacteria,1NI0K@1224|Proteobacteria,2UK2B@28211|Alphaproteobacteria,2K7A6@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2614132_12 314225.ELI_10150 2.27e-26 121.0 COG2003@1|root,COG2003@2|Bacteria 2|Bacteria L Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC PJD2_k127_2614132_7 1090318.ATTI01000001_gene1369 9.516e-60 214.0 COG3145@1|root,COG3145@2|Bacteria,1RDBK@1224|Proteobacteria,2U808@28211|Alphaproteobacteria,2K4HF@204457|Sphingomonadales 204457|Sphingomonadales L 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_2 PJD2_k127_2614132_0 517722.AEUE01000008_gene170 3.011e-260 806.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2TQUS@28211|Alphaproteobacteria,2K1QA@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 PJD2_k127_2614132_9 1219035.NT2_05_02710 5.772e-40 154.0 29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,2UKUZ@28211|Alphaproteobacteria,2K68C@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 PJD2_k127_2614132_3 1122970.AUHC01000004_gene2158 1.005e-151 499.0 COG1226@1|root,COG1226@2|Bacteria,1MXQP@1224|Proteobacteria,2TTRN@28211|Alphaproteobacteria,2K11P@204457|Sphingomonadales 204457|Sphingomonadales P COG1226 Kef-type K transport systems - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N PJD2_k127_2614132_6 314225.ELI_00600 1.922e-86 293.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2TUNI@28211|Alphaproteobacteria,2K0K8@204457|Sphingomonadales 204457|Sphingomonadales DM COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - LysM,Peptidase_M23 PJD2_k127_2614132_4 685035.ADAE01000004_gene1932 1.265e-131 427.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria,2K0F4@204457|Sphingomonadales 204457|Sphingomonadales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE PJD2_k127_2614132_5 1219035.NT2_05_02750 8.485e-119 388.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,2K0IX@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b PJD2_k127_2626604_9 555793.WSK_1646 1.252e-58 211.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2U5FI@28211|Alphaproteobacteria,2KD02@204457|Sphingomonadales 204457|Sphingomonadales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB PJD2_k127_2626604_10 291985.CCSI01000003_gene27 6.029e-57 214.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,2K5BJ@204457|Sphingomonadales 204457|Sphingomonadales O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran PJD2_k127_2626604_6 1382303.JPOM01000001_gene1389 3.166e-72 266.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2V60B@28211|Alphaproteobacteria,2KIX1@204458|Caulobacterales 204458|Caulobacterales E Amino acid permease - - - - - - - - - - - - AA_permease_2 PJD2_k127_2626604_13 291985.CCSI01000003_gene26 1.57e-32 139.0 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2UBWN@28211|Alphaproteobacteria,2K5VW@204457|Sphingomonadales 204457|Sphingomonadales H pterin-4-alpha-carbinolamine dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a PJD2_k127_2626604_4 291985.CCSI01000003_gene25 3.77e-128 414.0 COG4221@1|root,COG4221@2|Bacteria,1RAKI@1224|Proteobacteria,2TUJT@28211|Alphaproteobacteria,2K29E@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short PJD2_k127_2626604_0 685035.ADAE01000018_gene1097 2.633e-316 998.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2K37J@204457|Sphingomonadales 204457|Sphingomonadales E X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - PD40,Peptidase_S9 PJD2_k127_2626604_5 158500.BV97_02590 3.033e-99 329.0 COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria,2K0I0@204457|Sphingomonadales 204457|Sphingomonadales L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase - - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD PJD2_k127_2626604_11 291985.CCSI01000003_gene23 1.955e-52 188.0 COG0633@1|root,COG0633@2|Bacteria,1N261@1224|Proteobacteria,2UC7B@28211|Alphaproteobacteria,2K5DE@204457|Sphingomonadales 204457|Sphingomonadales C ferredoxin - - - ko:K04755 - - - - ko00000 - - - Fer2 PJD2_k127_2626604_2 314225.ELI_01730 5.098e-180 569.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,2K0XR@204457|Sphingomonadales 204457|Sphingomonadales E Cysteine synthase - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP PJD2_k127_2626604_14 237727.NAP1_00930 1.048e-15 81.0 2BNY5@1|root,32HN6@2|Bacteria,1NPJR@1224|Proteobacteria,2UMBD@28211|Alphaproteobacteria,2K80A@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2626604_8 279238.Saro_1123 6.599e-61 219.0 COG3225@1|root,COG3225@2|Bacteria,1NC9C@1224|Proteobacteria,2UH50@28211|Alphaproteobacteria,2K6HE@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - ABC_transp_aux PJD2_k127_2626604_7 314225.ELI_01750 9.227e-67 231.0 COG2001@1|root,COG2001@2|Bacteria,1RHCS@1224|Proteobacteria,2UBJA@28211|Alphaproteobacteria,2K5SD@204457|Sphingomonadales 204457|Sphingomonadales K Belongs to the MraZ family - - - ko:K03925 - - - - ko00000 - - - - PJD2_k127_2626604_3 314225.ELI_01755 7.399e-143 469.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,2K178@204457|Sphingomonadales 204457|Sphingomonadales J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 PJD2_k127_2626604_12 1219035.NT2_05_03940 2.107e-43 173.0 2AK00@1|root,31APD@2|Bacteria,1NHHT@1224|Proteobacteria,2UM7C@28211|Alphaproteobacteria,2K5VG@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2626604_1 1219035.NT2_05_03950 1.9e-274 854.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria,2K0Y2@204457|Sphingomonadales 204457|Sphingomonadales M Cell division protein FtsI penicillin-binding protein ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase PJD2_k127_2673574_6 1044.EH31_06825 4.515e-18 83.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2K11Z@204457|Sphingomonadales 204457|Sphingomonadales I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 PJD2_k127_2673574_5 1335760.ASTG01000003_gene1508 2.978e-52 190.0 COG4803@1|root,COG4803@2|Bacteria,1QU69@1224|Proteobacteria,2TW1D@28211|Alphaproteobacteria,2K498@204457|Sphingomonadales 204457|Sphingomonadales S membrane protein of uknown function UCP014873 - - - - - - - - - - - - - PJD2_k127_2673574_3 1248917.ANFX01000037_gene2106 1.097e-84 283.0 COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2TTCK@28211|Alphaproteobacteria,2K44J@204457|Sphingomonadales 204457|Sphingomonadales K transcriptional - - - - - - - - - - - - AsnC_trans_reg,HTH_24 PJD2_k127_2673574_1 314225.ELI_03080 1.001e-163 533.0 COG0642@1|root,COG0642@2|Bacteria,1RDQ3@1224|Proteobacteria,2U7I3@28211|Alphaproteobacteria,2KE9H@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - HisKA PJD2_k127_2673574_2 1479239.JQMU01000001_gene272 1.953e-141 457.0 COG0438@1|root,COG0438@2|Bacteria,1QWDV@1224|Proteobacteria,2TWWD@28211|Alphaproteobacteria,2KEHG@204457|Sphingomonadales 204457|Sphingomonadales M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - PJD2_k127_2673574_4 323848.Nmul_A1277 2.046e-75 280.0 COG2931@1|root,COG2931@2|Bacteria,1R4Z6@1224|Proteobacteria 1224|Proteobacteria Q domain protein - - - - - - - - - - - - - PJD2_k127_2673574_0 517722.AEUE01000007_gene466 2.794e-200 634.0 COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,2TSF8@28211|Alphaproteobacteria,2K0KQ@204457|Sphingomonadales 204457|Sphingomonadales S Peptidase, M28 - - - - - - - - - - - - PA,Peptidase_M28 PJD2_k127_2724155_5 314225.ELI_01800 3.527e-174 551.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,2K03S@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M PJD2_k127_2724155_7 1122970.AUHC01000005_gene2045 9.815e-151 492.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,2K0QA@204457|Sphingomonadales 204457|Sphingomonadales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C PJD2_k127_2724155_4 1219035.NT2_05_04040 1.757e-179 565.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,2K0W3@204457|Sphingomonadales 204457|Sphingomonadales M Cell wall formation ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N PJD2_k127_2724155_11 314225.ELI_01815 1.081e-122 400.0 COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,2K1JE@204457|Sphingomonadales 204457|Sphingomonadales D Cell division protein FtsQ ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 PJD2_k127_2724155_2 1219035.NT2_05_04060 6.93e-203 649.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,2K082@204457|Sphingomonadales 204457|Sphingomonadales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA PJD2_k127_2724155_1 314225.ELI_01825 1.064e-221 701.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,2K16V@204457|Sphingomonadales 204457|Sphingomonadales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin PJD2_k127_2724155_13 314225.ELI_01830 8.413e-119 403.0 COG0457@1|root,COG0457@2|Bacteria,1QNIE@1224|Proteobacteria,2TVQA@28211|Alphaproteobacteria,2K08T@204457|Sphingomonadales 204457|Sphingomonadales U Tetratricopeptide repeat - - - - - - - - - - - - SPOR,TPR_19 PJD2_k127_2724155_18 1219035.NT2_05_04090 5.194e-81 272.0 COG5465@1|root,COG5465@2|Bacteria,1REC1@1224|Proteobacteria,2U7UP@28211|Alphaproteobacteria,2K1T3@204457|Sphingomonadales 204457|Sphingomonadales S Putative bacterial sensory transduction regulator - - - - - - - - - - - - YbjN PJD2_k127_2724155_17 314225.ELI_01840 1.554e-93 314.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria,2K353@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer PJD2_k127_2724155_15 685035.ADAE01000018_gene1072 1.816e-100 334.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,2K14K@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the BI1 family - - - ko:K06890 - - - - ko00000 - - - Bax1-I PJD2_k127_2724155_20 161528.ED21_30684 9.965e-67 237.0 2FE0D@1|root,3460K@2|Bacteria,1N3CI@1224|Proteobacteria,2U96F@28211|Alphaproteobacteria,2K5QV@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - SPOR PJD2_k127_2724155_3 383381.EH30_01955 1.034e-189 596.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,2K1GJ@204457|Sphingomonadales 204457|Sphingomonadales S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 PJD2_k127_2724155_8 702113.PP1Y_AT7604 1.252e-138 450.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,2K0DF@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA PJD2_k127_2724155_14 314225.ELI_01865 4.257e-109 372.0 COG0702@1|root,COG0702@2|Bacteria,1RCCP@1224|Proteobacteria,2TU1D@28211|Alphaproteobacteria,2K0TF@204457|Sphingomonadales 204457|Sphingomonadales GM epimerase - - - - - - - - - - - - NAD_binding_10 PJD2_k127_2724155_10 158500.BV97_00146 5.516e-125 405.0 COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2U5AP@28211|Alphaproteobacteria,2K0FD@204457|Sphingomonadales 204457|Sphingomonadales EH Reduction of activated sulfate into sulfite cysH - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct PJD2_k127_2724155_21 1346791.M529_15910 1.109e-55 203.0 COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2UDH7@28211|Alphaproteobacteria,2KD7Z@204457|Sphingomonadales 204457|Sphingomonadales S Bacterial protein of unknown function (DUF934) - - - - - - - - - - - - DUF934 PJD2_k127_2724155_0 1174684.EBMC1_09929 6.804e-302 930.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria,2K14A@204457|Sphingomonadales 204457|Sphingomonadales C Sulfite reductase cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr PJD2_k127_2724155_23 1502850.FG91_02138 3.27e-41 157.0 2EG12@1|root,339T3@2|Bacteria,1NGID@1224|Proteobacteria,2UK0A@28211|Alphaproteobacteria,2K5XT@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF2849) - - - - - - - - - - - - DUF2849 PJD2_k127_2724155_12 237727.NAP1_01095 1.377e-120 391.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,2K1SG@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the precorrin methyltransferase family cysG - 2.1.1.107 ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - TP_methylase PJD2_k127_2724155_9 161528.ED21_24036 3.614e-128 437.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,2K0A6@204457|Sphingomonadales 204457|Sphingomonadales M mechanosensitive ion channel - - - - - - - - - - - - MS_channel PJD2_k127_2724155_6 161528.ED21_24031 4.832e-173 553.0 COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2TS8Z@28211|Alphaproteobacteria,2K0WB@204457|Sphingomonadales 204457|Sphingomonadales E cystathionine beta-lyase metC - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP PJD2_k127_2724155_16 383381.EH30_02005 3.021e-98 340.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,2K1GF@204457|Sphingomonadales 204457|Sphingomonadales P Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese PJD2_k127_2724155_19 161528.ED21_24016 1.058e-75 255.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2U57X@28211|Alphaproteobacteria,2K3W2@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF PJD2_k127_2726615_4 314225.ELI_12600 3.07e-18 85.0 2DHUM@1|root,3010J@2|Bacteria,1P10Y@1224|Proteobacteria,2UVE6@28211|Alphaproteobacteria,2KB2Z@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2726615_2 291985.CCSI01000002_gene1513 1.895e-77 266.0 COG5321@1|root,COG5321@2|Bacteria,1RDXW@1224|Proteobacteria,2U73Y@28211|Alphaproteobacteria,2K4NV@204457|Sphingomonadales 204457|Sphingomonadales S DNA repair protein MmcB-like - - - - - - - - - - - - MmcB-like PJD2_k127_2726615_0 702113.PP1Y_AT36759 6.596e-120 388.0 COG3000@1|root,COG3000@2|Bacteria,1NXAF@1224|Proteobacteria,2TRF0@28211|Alphaproteobacteria,2K0X1@204457|Sphingomonadales 204457|Sphingomonadales I sterol desaturase - - - - - - - - - - - - FA_hydroxylase PJD2_k127_2726615_3 702113.PP1Y_AT36765 9.107e-36 154.0 COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,2UEB7@28211|Alphaproteobacteria,2K5WY@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF2141 PJD2_k127_2726615_1 314225.ELI_12620 1.233e-101 343.0 COG5388@1|root,COG5388@2|Bacteria,1R74W@1224|Proteobacteria,2TUTW@28211|Alphaproteobacteria,2K1EC@204457|Sphingomonadales 204457|Sphingomonadales S PAS domain - - - - - - - - - - - - - PJD2_k127_2735786_25 1248917.ANFX01000023_gene1242 1.799e-20 94.0 COG4585@1|root,COG4585@2|Bacteria,1RKV1@1224|Proteobacteria,2U32D@28211|Alphaproteobacteria,2KDGC@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 PJD2_k127_2735786_20 279238.Saro_1236 8.645e-65 230.0 COG2197@1|root,COG2197@2|Bacteria,1RGH6@1224|Proteobacteria,2U81B@28211|Alphaproteobacteria,2K60U@204457|Sphingomonadales 204457|Sphingomonadales T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg PJD2_k127_2735786_1 279238.Saro_1421 1.741e-291 912.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales 204457|Sphingomonadales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9,PilZ PJD2_k127_2735786_10 1479239.JQMU01000001_gene368 3.345e-121 398.0 COG0778@1|root,COG0778@2|Bacteria,1MWMJ@1224|Proteobacteria,2TU8B@28211|Alphaproteobacteria,2K1M9@204457|Sphingomonadales 204457|Sphingomonadales C Nitroreductase family - - - - - - - - - - - - Nitroreductase PJD2_k127_2735786_5 314225.ELI_04745 3.194e-218 684.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,2TSKB@28211|Alphaproteobacteria,2K02Y@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the Orn Lys Arg decarboxylase class-II family speF - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC PJD2_k127_2735786_4 161528.ED21_29761 4.47e-220 689.0 COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,2TVR1@28211|Alphaproteobacteria,2K0YP@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily - - 4.1.1.96 ko:K13747 ko00330,ko01100,map00330,map01100 - R09081,R09082 RC00299 ko00000,ko00001,ko01000 - - - Orn_DAP_Arg_deC PJD2_k127_2735786_3 383381.EH30_04640 1.122e-250 779.0 COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,2TRRQ@28211|Alphaproteobacteria,2K1EZ@204457|Sphingomonadales 204457|Sphingomonadales E Saccharopine dehydrogenase - - 1.5.1.7 ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715 RC00217,RC01532 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP PJD2_k127_2735786_9 314225.ELI_04715 1.312e-153 490.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K27R@204457|Sphingomonadales 204457|Sphingomonadales E Threonine dehydratase - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP PJD2_k127_2735786_23 314225.ELI_04710 1.656e-56 201.0 COG5331@1|root,COG5331@2|Bacteria,1RI4N@1224|Proteobacteria,2UA3C@28211|Alphaproteobacteria,2K5DV@204457|Sphingomonadales 204457|Sphingomonadales S MAPEG family - - - - - - - - - - - - MAPEG PJD2_k127_2735786_22 1122612.AUBA01000013_gene258 4.141e-61 213.0 COG5331@1|root,COG5331@2|Bacteria,1N0MD@1224|Proteobacteria,2UAEC@28211|Alphaproteobacteria,2KDI3@204457|Sphingomonadales 204457|Sphingomonadales S MAPEG family - - - - - - - - - - - - MAPEG PJD2_k127_2735786_7 1219035.NT2_02_05140 1.782e-173 557.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,2K0I2@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 PJD2_k127_2735786_12 161528.ED21_29801 2.386e-106 351.0 COG2365@1|root,COG2365@2|Bacteria,1R4XF@1224|Proteobacteria,2U0KA@28211|Alphaproteobacteria,2K2AD@204457|Sphingomonadales 204457|Sphingomonadales T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 PJD2_k127_2735786_18 517722.AEUE01000003_gene1455 3.417e-72 249.0 COG3577@1|root,COG3577@2|Bacteria,1R74B@1224|Proteobacteria,2UBEE@28211|Alphaproteobacteria,2K1P8@204457|Sphingomonadales 204457|Sphingomonadales S gag-polyprotein putative aspartyl protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas PJD2_k127_2735786_8 314225.ELI_08440 3.026e-154 503.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2TRMH@28211|Alphaproteobacteria,2K0WW@204457|Sphingomonadales 204457|Sphingomonadales S Histidine-specific methyltransferase, SAM-dependent - - - - - - - - - - - - Methyltransf_33 PJD2_k127_2735786_6 1248917.ANFX01000032_gene846 3.782e-207 651.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,2K0TI@204457|Sphingomonadales 204457|Sphingomonadales S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase PJD2_k127_2735786_11 1248760.ANFZ01000012_gene59 7.793e-116 382.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2TS3Z@28211|Alphaproteobacteria,2K0EV@204457|Sphingomonadales 204457|Sphingomonadales C Alcohol dehydrogenase zinc-binding domain protein - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N PJD2_k127_2735786_2 1248917.ANFX01000032_gene847 3.004e-261 808.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2TR0E@28211|Alphaproteobacteria,2K0JX@204457|Sphingomonadales 204457|Sphingomonadales E phospho-2-dehydro-3-deoxyheptonate aldolase aroF - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 PJD2_k127_2735786_0 314225.ELI_08455 0.0 1281.0 COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,2U0S5@28211|Alphaproteobacteria,2K0RS@204457|Sphingomonadales 204457|Sphingomonadales S Peptidase, M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_2735786_13 685035.ADAE01000002_gene2550 3.615e-99 327.0 COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,2K0IN@204457|Sphingomonadales 204457|Sphingomonadales O COG0694 Thioredoxin-like proteins and domains - - - - - - - - - - - - Nfu_N,NifU PJD2_k127_2735786_14 1248917.ANFX01000032_gene850 2.238e-95 315.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2U5B0@28211|Alphaproteobacteria,2K16Z@204457|Sphingomonadales 204457|Sphingomonadales C Nitroreductase family - - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase PJD2_k127_2735786_21 314225.ELI_08470 1.185e-61 218.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,2K59A@204457|Sphingomonadales 204457|Sphingomonadales O peptidase M22 - - - - - - - - - - - - Peptidase_M22 PJD2_k127_2735786_24 314225.ELI_08475 1.036e-53 201.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,2K616@204457|Sphingomonadales 204457|Sphingomonadales K Acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 PJD2_k127_2735786_19 314225.ELI_08480 1.727e-65 227.0 COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria,2K5ZE@204457|Sphingomonadales 204457|Sphingomonadales K ROS/MUCR transcriptional regulator protein - - - - - - - - - - - - ROS_MUCR PJD2_k127_2735786_17 1122612.AUBA01000003_gene1579 4.947e-77 259.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2U6ZS@28211|Alphaproteobacteria,2K3Z2@204457|Sphingomonadales 204457|Sphingomonadales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR PJD2_k127_2735786_16 279238.Saro_0983 1.388e-77 270.0 COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2TT8Q@28211|Alphaproteobacteria,2K221@204457|Sphingomonadales 204457|Sphingomonadales I Acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase PJD2_k127_2735786_15 1122970.AUHC01000008_gene113 2.462e-85 284.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,2K1NH@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 PJD2_k127_2736572_14 314225.ELI_06515 6.05e-37 140.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,2K0PS@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the TrpC family trpC - 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS PJD2_k127_2736572_12 161528.ED21_27858 5.503e-63 219.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2K4GG@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC PJD2_k127_2736572_9 383381.EH30_06415 6.929e-109 358.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,2K1AX@204457|Sphingomonadales 204457|Sphingomonadales K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 PJD2_k127_2736572_0 314225.ELI_06535 1.407e-284 891.0 COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria,2K0XJ@204457|Sphingomonadales 204457|Sphingomonadales S membrane metal-binding protein - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 PJD2_k127_2736572_4 1248917.ANFX01000010_gene200 1.384e-239 747.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,2K09A@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX1 - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c PJD2_k127_2736572_3 383381.EH30_06430 2.074e-263 813.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,2K0JS@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt PJD2_k127_2736572_17 1144305.PMI02_01485 4.266e-13 70.0 2C7HC@1|root,2ZEX5@2|Bacteria,1N7NS@1224|Proteobacteria,2UGBA@28211|Alphaproteobacteria,2K7T5@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2736572_7 291985.CCSI01000001_gene2401 1.774e-162 525.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U3HG@28211|Alphaproteobacteria,2K0AE@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA PJD2_k127_2736572_10 314225.ELI_06560 1.138e-100 337.0 COG0645@1|root,COG0645@2|Bacteria,1RFFP@1224|Proteobacteria,2U8D3@28211|Alphaproteobacteria,2K50S@204457|Sphingomonadales 204457|Sphingomonadales S Protein conserved in bacteria - - - - - - - - - - - - - PJD2_k127_2736572_13 1219035.NT2_02_00260 2.805e-40 164.0 2AKKZ@1|root,31BDD@2|Bacteria,1NNE3@1224|Proteobacteria,2UMPR@28211|Alphaproteobacteria,2K72H@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2736572_16 555793.WSK_1071 4.325e-32 130.0 2AFMU@1|root,315P6@2|Bacteria,1NDJZ@1224|Proteobacteria,2UHNJ@28211|Alphaproteobacteria,2K65G@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2736572_5 314225.ELI_06575 3.208e-238 764.0 COG1196@1|root,COG1196@2|Bacteria,1MVEP@1224|Proteobacteria,2TR50@28211|Alphaproteobacteria,2K0N2@204457|Sphingomonadales 204457|Sphingomonadales D nuclear chromosome segregation - - - - - - - - - - - - - PJD2_k127_2736572_15 1122970.AUHC01000001_gene571 6.64e-33 128.0 COG5454@1|root,COG5454@2|Bacteria,1N8U9@1224|Proteobacteria,2UGCD@28211|Alphaproteobacteria,2K711@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1467) - - - - - - - - - - - - DUF1467 PJD2_k127_2736572_1 1219035.NT2_02_00300 1.759e-278 863.0 COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,2TQTR@28211|Alphaproteobacteria,2K04C@204457|Sphingomonadales 204457|Sphingomonadales S metallo-beta-lactamase - - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2,RMMBL PJD2_k127_2736572_8 161528.ED21_27918 1.792e-131 436.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2TS5A@28211|Alphaproteobacteria,2K0SW@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase PJD2_k127_2736572_11 291985.CCSI01000001_gene2408 1.979e-93 314.0 COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,2JZZZ@204457|Sphingomonadales 204457|Sphingomonadales H biotin lipoate A B protein ligase birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,BPL_LplA_LipB_2 PJD2_k127_2736572_6 702113.PP1Y_AT27295 1.019e-219 691.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,2K08E@204457|Sphingomonadales 204457|Sphingomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M PJD2_k127_2736572_2 291985.CCSI01000001_gene2410 7.406e-264 818.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,2K0EQ@204457|Sphingomonadales 204457|Sphingomonadales C NADH ubiquinone oxidoreductase subunit nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M PJD2_k127_2760313_7 291985.CCSI01000004_gene770 4.677e-15 87.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2V1FI@28211|Alphaproteobacteria,2KBH4@204457|Sphingomonadales 204457|Sphingomonadales O Subtilase family - - - - - - - - - - - - Peptidase_S8 PJD2_k127_2760313_4 383381.EH30_02430 2.543e-95 321.0 COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,2U0BH@28211|Alphaproteobacteria,2K0H5@204457|Sphingomonadales 204457|Sphingomonadales M aspartate racemase - - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race PJD2_k127_2760313_3 685035.ADAE01000018_gene979 1.104e-110 384.0 COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,2TTCT@28211|Alphaproteobacteria,2K1SM@204457|Sphingomonadales 204457|Sphingomonadales I Alpha beta hydrolase - - - ko:K18092 ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220 - R05366 RC00752,RC00753 br01602,ko00000,ko00001,ko01000 - - - Abhydrolase_1,Abhydrolase_6 PJD2_k127_2760313_2 161528.ED21_24366 2.242e-113 370.0 COG2010@1|root,COG2010@2|Bacteria,1QUPA@1224|Proteobacteria,2U3YK@28211|Alphaproteobacteria,2K21S@204457|Sphingomonadales 204457|Sphingomonadales C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 PJD2_k127_2760313_8 1122970.AUHC01000005_gene1932 2.102e-11 76.0 COG2010@1|root,COG2010@2|Bacteria,1QUPA@1224|Proteobacteria,2U3YK@28211|Alphaproteobacteria,2K21S@204457|Sphingomonadales 204457|Sphingomonadales C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 PJD2_k127_2760313_1 685035.ADAE01000018_gene981 1.309e-172 550.0 COG3420@1|root,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,2TTFV@28211|Alphaproteobacteria,2K0ZB@204457|Sphingomonadales 204457|Sphingomonadales P Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - Beta_helix PJD2_k127_2760313_6 1449076.JOOE01000003_gene3456 1.287e-22 113.0 2CTAY@1|root,32ST0@2|Bacteria,1N57M@1224|Proteobacteria,2UDXZ@28211|Alphaproteobacteria,2K67J@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2760313_5 314225.ELI_02355 5.872e-25 120.0 297IB@1|root,2ZURJ@2|Bacteria,1NA2F@1224|Proteobacteria,2UH54@28211|Alphaproteobacteria,2K6A7@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_2760313_0 702113.PP1Y_AT28001 1.092e-220 688.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,2K05C@204457|Sphingomonadales 204457|Sphingomonadales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB PJD2_k127_2790353_1 314225.ELI_13140 4.063e-212 676.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,2K2A0@204457|Sphingomonadales 204457|Sphingomonadales M membrane - - - - - - - - - - - - Peptidase_M23 PJD2_k127_2790353_0 291985.CCSI01000002_gene1413 0.0 1149.0 COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,2JZXM@204457|Sphingomonadales 204457|Sphingomonadales L helicase - - 3.6.4.13 ko:K17675 - - - - ko00000,ko01000,ko03029 - - - Helicase_C PJD2_k127_2790353_4 1144305.PMI02_04220 3.917e-25 107.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2UBS3@28211|Alphaproteobacteria,2K6XI@204457|Sphingomonadales 204457|Sphingomonadales J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) hslR - - ko:K04762 - - - - ko00000,ko03110 - - - S4 PJD2_k127_2790353_3 685035.ADAE01000023_gene1607 1.039e-68 234.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,2K4E8@204457|Sphingomonadales 204457|Sphingomonadales C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4,Fer4_4 PJD2_k127_2790353_2 685035.ADAE01000023_gene1610 8.441e-99 325.0 COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,2TTVP@28211|Alphaproteobacteria,2K0TA@204457|Sphingomonadales 204457|Sphingomonadales K CarD family transcriptional regulator - - - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF PJD2_k127_296951_4 1219035.NT2_02_05960 4.762e-58 224.0 COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U1YP@28211|Alphaproteobacteria,2K2T9@204457|Sphingomonadales 204457|Sphingomonadales Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - VWA_2 PJD2_k127_296951_3 291985.CCSI01000007_gene481 7.003e-66 239.0 COG2885@1|root,COG2885@2|Bacteria,1RM6V@1224|Proteobacteria,2UB11@28211|Alphaproteobacteria,2K57I@204457|Sphingomonadales 204457|Sphingomonadales M OmpA family - - - - - - - - - - - - OmpA PJD2_k127_296951_1 291985.CCSI01000007_gene480 1.315e-194 619.0 COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,2U11S@28211|Alphaproteobacteria,2K36Y@204457|Sphingomonadales 204457|Sphingomonadales MU Outer membrane efflux protein - - - ko:K12543 - M00330 - - ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 - - OEP PJD2_k127_296951_0 291985.CCSI01000007_gene479 5.935e-286 895.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2USBQ@28211|Alphaproteobacteria,2K0KD@204457|Sphingomonadales 204457|Sphingomonadales V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran PJD2_k127_296951_2 1219035.NT2_02_05920 2.911e-81 279.0 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,2K40Z@204457|Sphingomonadales 204457|Sphingomonadales M Cell Wall Hydrolase - - - - - - - - - - - - Hydrolase_2 PJD2_k127_302840_2 314225.ELI_12590 2.059e-229 726.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K1MV@204457|Sphingomonadales 204457|Sphingomonadales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C PJD2_k127_302840_3 279238.Saro_2348 1.516e-181 575.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2K0AI@204457|Sphingomonadales 204457|Sphingomonadales S amidohydrolase - - - - - - - - - - - - M20_dimer,Peptidase_M20 PJD2_k127_302840_6 314225.ELI_12585 1.191e-97 328.0 COG1597@1|root,COG1597@2|Bacteria,1RIZ6@1224|Proteobacteria,2U6ZJ@28211|Alphaproteobacteria,2KCD0@204457|Sphingomonadales 204457|Sphingomonadales I Diacylglycerol kinase catalytic domain (presumed) - - - - - - - - - - - - DAGK_cat PJD2_k127_302840_5 158500.BV97_04203 8.87e-111 375.0 COG1597@1|root,COG1597@2|Bacteria,1RB97@1224|Proteobacteria,2TW41@28211|Alphaproteobacteria,2KEA6@204457|Sphingomonadales 204457|Sphingomonadales I lipid kinase activity - - - - - - - - - - - - - PJD2_k127_302840_7 314225.ELI_12575 1.368e-64 229.0 COG4704@1|root,COG4704@2|Bacteria,1REQD@1224|Proteobacteria,2U8UI@28211|Alphaproteobacteria,2K510@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF2141 PJD2_k127_302840_4 983920.Y88_2073 5.84e-124 399.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,2K1ZB@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim PJD2_k127_302840_0 1219035.NT2_04_01900 1.184e-277 866.0 COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,2K1RQ@204457|Sphingomonadales 204457|Sphingomonadales S Heparinase - - - - - - - - - - - - Hepar_II_III PJD2_k127_302840_1 1219035.NT2_04_01890 2.114e-269 836.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,2K0R5@204457|Sphingomonadales 204457|Sphingomonadales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS PJD2_k127_3035336_5 161528.ED21_28298 1.426e-128 418.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,2K010@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the DNA photolyase family phrB - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 PJD2_k127_3035336_8 291985.CCSI01000001_gene2484 7.084e-99 333.0 COG0671@1|root,COG0671@2|Bacteria,1RDK3@1224|Proteobacteria,2U7BJ@28211|Alphaproteobacteria,2K515@204457|Sphingomonadales 204457|Sphingomonadales I Acid phosphatase homologues - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 PJD2_k127_3035336_2 314225.ELI_07065 2.815e-193 640.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria,2K1JI@204457|Sphingomonadales 204457|Sphingomonadales C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C PJD2_k127_3035336_4 314225.ELI_07070 1.852e-152 485.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,2K2JW@204457|Sphingomonadales 204457|Sphingomonadales C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N PJD2_k127_3035336_1 314225.ELI_07070 1.127e-205 642.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,2K2JW@204457|Sphingomonadales 204457|Sphingomonadales C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N PJD2_k127_3035336_6 291985.CCSI01000001_gene2488 1.822e-126 412.0 COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2U5X1@28211|Alphaproteobacteria,2JZVT@204457|Sphingomonadales 204457|Sphingomonadales I PFAM Alpha beta hydrolase fold-3 domain protein - - - - - - - - - - - - Abhydrolase_3 PJD2_k127_3035336_9 291985.CCSI01000001_gene2489 3.254e-78 263.0 COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,2K4S3@204457|Sphingomonadales 204457|Sphingomonadales F Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX PJD2_k127_3035336_10 314225.ELI_07085 1.172e-59 212.0 COG3063@1|root,COG3063@2|Bacteria,1RJ27@1224|Proteobacteria,2U9I7@28211|Alphaproteobacteria,2KE6E@204457|Sphingomonadales 204457|Sphingomonadales NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 PJD2_k127_3035336_3 702113.PP1Y_AT30588 5.174e-156 501.0 COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,2K17G@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F PJD2_k127_3035336_0 237727.NAP1_06335 4.856e-262 813.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,2K0CG@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH,NMO PJD2_k127_3035336_7 1096930.L284_07480 3.099e-113 377.0 COG2234@1|root,COG2234@2|Bacteria,1R88X@1224|Proteobacteria,2U1MC@28211|Alphaproteobacteria,2K3J3@204457|Sphingomonadales 204457|Sphingomonadales S M42 glutamyl aminopeptidase - - - - - - - - - - - - PA,Peptidase_M28 PJD2_k127_3038642_1 685035.ADAE01000020_gene1473 3.059e-71 244.0 COG0583@1|root,COG0583@2|Bacteria,1MXC9@1224|Proteobacteria,2TTTY@28211|Alphaproteobacteria,2K5KF@204457|Sphingomonadales 204457|Sphingomonadales K DNA-binding transcription factor activity - - - - - - - - - - - - - PJD2_k127_3038642_2 392499.Swit_4074 1.867e-70 245.0 COG0558@1|root,COG0558@2|Bacteria,1RAA0@1224|Proteobacteria,2U5VB@28211|Alphaproteobacteria,2K46F@204457|Sphingomonadales 204457|Sphingomonadales I CDP-alcohol phosphatidyltransferase - - - - - - - - - - - - CDP-OH_P_transf PJD2_k127_3038642_0 685035.ADAE01000020_gene1475 3.432e-235 733.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,2K0QQ@204457|Sphingomonadales 204457|Sphingomonadales S of ABC transporters with duplicated ATPase - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD PJD2_k127_304539_7 685035.ADAE01000003_gene2743 3.084e-246 772.0 COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,2K1CG@204457|Sphingomonadales 204457|Sphingomonadales G Alpha-amylase domain - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459 PJD2_k127_304539_2 291985.CCSI01000008_gene1044 1.329e-286 898.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,2U0DP@28211|Alphaproteobacteria,2K0HA@204457|Sphingomonadales 204457|Sphingomonadales G Alpha-amylase domain - - - - - - - - - - - - Alpha-amylase,Malt_amylase_C PJD2_k127_304539_9 1112214.AHIS01000089_gene899 3.607e-231 727.0 COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2TTKE@28211|Alphaproteobacteria,2JZZ7@204457|Sphingomonadales 204457|Sphingomonadales E Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase PJD2_k127_304539_1 1112214.AHIS01000089_gene898 0.0 1114.0 COG1629@1|root,COG1629@2|Bacteria,1MWTT@1224|Proteobacteria,2TURM@28211|Alphaproteobacteria,2K1TV@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - OMP_b-brl_3,Plug,TonB_dep_Rec PJD2_k127_304539_14 291985.CCSI01000008_gene1048 3.405e-170 540.0 COG1609@1|root,COG1609@2|Bacteria,1MW7E@1224|Proteobacteria,2TV4Q@28211|Alphaproteobacteria,2K0IK@204457|Sphingomonadales 204457|Sphingomonadales K COG1609 Transcriptional regulators - - - - - - - - - - - - LacI,Peripla_BP_3 PJD2_k127_304539_5 314225.ELI_03150 2.034e-265 824.0 COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2TTX5@28211|Alphaproteobacteria,2K0AH@204457|Sphingomonadales 204457|Sphingomonadales G COG0477 Permeases of the major facilitator superfamily - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 PJD2_k127_304539_21 685035.ADAE01000003_gene2749 8.104e-49 177.0 COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,2TVJ1@28211|Alphaproteobacteria,2K2D2@204457|Sphingomonadales 204457|Sphingomonadales G Glycogen debranching enzyme, glucanotransferase domain - - - - - - - - - - - - Alpha-amylase,Malt_amylase_C PJD2_k127_304539_12 685035.ADAE01000003_gene2749 5.759e-185 582.0 COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,2TVJ1@28211|Alphaproteobacteria,2K2D2@204457|Sphingomonadales 204457|Sphingomonadales G Glycogen debranching enzyme, glucanotransferase domain - - - - - - - - - - - - Alpha-amylase,Malt_amylase_C PJD2_k127_304539_8 1123267.JONN01000001_gene1888 3.236e-240 751.0 COG0477@1|root,COG0477@2|Bacteria,1QTYG@1224|Proteobacteria,2U3R4@28211|Alphaproteobacteria,2K1BE@204457|Sphingomonadales 204457|Sphingomonadales EGP Sugar (and other) transporter - - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1 PJD2_k127_304539_20 1044.EH31_05265 1.572e-83 293.0 COG2211@1|root,COG2211@2|Bacteria,1RCS5@1224|Proteobacteria,2U6WZ@28211|Alphaproteobacteria,2K4M4@204457|Sphingomonadales 204457|Sphingomonadales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 PJD2_k127_304539_6 1248760.ANFZ01000018_gene621 3.44e-259 806.0 COG0644@1|root,COG0644@2|Bacteria,1R41S@1224|Proteobacteria,2TW03@28211|Alphaproteobacteria,2KE9W@204457|Sphingomonadales 204457|Sphingomonadales C Tryptophan halogenase - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Trp_halogenase PJD2_k127_304539_0 1248760.ANFZ01000018_gene622 0.0 1463.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,2TSUV@28211|Alphaproteobacteria,2JZV0@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_304539_18 1123270.ATUR01000002_gene2065 4.659e-107 360.0 COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,2TSG2@28211|Alphaproteobacteria,2K0V1@204457|Sphingomonadales 204457|Sphingomonadales S A domain family that is part of the cupin metalloenzyme superfamily. - - - - - - - - - - - - Cupin_8 PJD2_k127_304539_16 1502850.FG91_00027 7.773e-152 486.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2U2E9@28211|Alphaproteobacteria,2K0ED@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 PJD2_k127_304539_4 317655.Sala_1511 4.028e-283 891.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2TS28@28211|Alphaproteobacteria,2K11N@204457|Sphingomonadales 204457|Sphingomonadales G Glycosyl hydrolase family 3 C-terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Glyco_hydro_3,Glyco_hydro_3_C PJD2_k127_304539_10 317655.Sala_1395 2.87e-212 667.0 COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,2TSVP@28211|Alphaproteobacteria,2K028@204457|Sphingomonadales 204457|Sphingomonadales G Transporter - - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 PJD2_k127_304539_17 1123270.ATUR01000010_gene1874 2.665e-118 408.0 COG2273@1|root,COG2273@2|Bacteria,1R91A@1224|Proteobacteria,2TXKQ@28211|Alphaproteobacteria,2K35C@204457|Sphingomonadales 204457|Sphingomonadales G Glycosyl hydrolases family 16 - - - - - - - - - - - - Glyco_hydro_16 PJD2_k127_304539_11 1112214.AHIS01000092_gene481 8.214e-200 634.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2TQXA@28211|Alphaproteobacteria,2K20G@204457|Sphingomonadales 204457|Sphingomonadales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N PJD2_k127_304539_3 1219035.NT2_05_02670 2.238e-286 889.0 COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,2TQNS@28211|Alphaproteobacteria,2K1X3@204457|Sphingomonadales 204457|Sphingomonadales EG Belongs to the IlvD Edd family - - 4.2.1.12 ko:K01690 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00008 R02036 RC00543 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD PJD2_k127_304539_13 291985.CCSI01000003_gene187 9.692e-173 549.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2U0CA@28211|Alphaproteobacteria,2K0NK@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase PJD2_k127_304539_19 161528.ED21_22303 5.24e-98 327.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2TUMH@28211|Alphaproteobacteria,2K1HN@204457|Sphingomonadales 204457|Sphingomonadales G Aldolase eda GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase PJD2_k127_304539_15 1112216.JH594425_gene3150 6.822e-167 530.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2K0VS@204457|Sphingomonadales 204457|Sphingomonadales C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red PJD2_k127_304539_22 383381.EH30_14310 1.229e-43 165.0 COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,2TV2J@28211|Alphaproteobacteria,2KDNP@204457|Sphingomonadales 204457|Sphingomonadales S oligosaccharyl transferase activity - - - - - - - - - - - - - PJD2_k127_3075890_6 1123258.AQXZ01000016_gene2451 5.164e-81 279.0 COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4FYCV@85025|Nocardiaceae 201174|Actinobacteria IQ KR domain - - 1.1.1.53 ko:K00038 ko00140,ko01100,map00140,map01100 - R04831,R04834,R04844,R04847 RC00139,RC01219,RC01220 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 PJD2_k127_3075890_3 1088721.NSU_0084 3.633e-195 617.0 COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,2TZDG@28211|Alphaproteobacteria,2K2DE@204457|Sphingomonadales 204457|Sphingomonadales C Acetyl-CoA hydrolase/transferase C-terminal domain - - - ko:K18288 ko00660,map00660 - R02407,R10600 RC00012,RC00014 ko00000,ko00001,ko01000 - - - AcetylCoA_hyd_C,AcetylCoA_hydro PJD2_k127_3075890_0 1088721.NSU_3777 2.082e-300 950.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,2K18Q@204457|Sphingomonadales 204457|Sphingomonadales P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase PJD2_k127_3075890_1 1545915.JROG01000007_gene3072 8.275e-284 883.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,2K1B4@204457|Sphingomonadales 204457|Sphingomonadales S of ABC transporters with duplicated ATPase - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn PJD2_k127_3075890_5 1219035.NT2_01_00610 2.171e-137 447.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2TR46@28211|Alphaproteobacteria,2K1ZG@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_8 PJD2_k127_3075890_4 161528.ED21_29003 1.483e-153 499.0 COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria,2K0M7@204457|Sphingomonadales 204457|Sphingomonadales P Phosphate ABC transporter substrate-binding protein pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 PJD2_k127_3075890_2 291985.CCSI01000001_gene2654 2.628e-217 682.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2TQU1@28211|Alphaproteobacteria,2K16C@204457|Sphingomonadales 204457|Sphingomonadales P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3708 PJD2_k127_3075890_7 291985.CCSI01000001_gene2655 1.15e-43 165.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,2JZYA@204457|Sphingomonadales 204457|Sphingomonadales P phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 PJD2_k127_3105024_5 1266998.ATUJ01000007_gene280 7.674e-08 53.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2U7CH@28211|Alphaproteobacteria,2PVNB@265|Paracoccus 28211|Alphaproteobacteria E N-(5'phosphoribosyl)anthranilate (PRA) isomerase trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI PJD2_k127_3105024_0 291985.CCSI01000001_gene2205 1.028e-241 752.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria,2K1IA@204457|Sphingomonadales 204457|Sphingomonadales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP PJD2_k127_3105024_4 291985.CCSI01000001_gene2203 2.298e-128 415.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2TQN2@28211|Alphaproteobacteria,2K0XH@204457|Sphingomonadales 204457|Sphingomonadales E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA PJD2_k127_3105024_3 291985.CCSI01000001_gene2202 1.948e-147 473.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2TRSH@28211|Alphaproteobacteria,2K159@204457|Sphingomonadales 204457|Sphingomonadales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans PJD2_k127_3105024_2 1096930.L284_07295 9.172e-201 632.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria,2K1S3@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M PJD2_k127_3105024_1 1479239.JQMU01000001_gene245 2.699e-218 687.0 COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,2TW2A@28211|Alphaproteobacteria,2KEGA@204457|Sphingomonadales 204457|Sphingomonadales G Acetyl-coenzyme A transporter 1 - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 PJD2_k127_3136960_0 291985.CCSI01000002_gene1321 0.0 1226.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,2K0I6@204457|Sphingomonadales 204457|Sphingomonadales L helicase lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C PJD2_k127_3136960_10 314225.ELI_13740 1.206e-57 203.0 COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2UEA0@28211|Alphaproteobacteria,2K55Z@204457|Sphingomonadales 204457|Sphingomonadales U Biopolymer transport protein - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD PJD2_k127_3136960_8 1219035.NT2_04_04430 2.907e-90 299.0 COG0848@1|root,COG0848@2|Bacteria,1R64K@1224|Proteobacteria,2U4H6@28211|Alphaproteobacteria,2KD52@204457|Sphingomonadales 204457|Sphingomonadales U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD PJD2_k127_3136960_6 279238.Saro_0016 4.769e-112 367.0 COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2TS4F@28211|Alphaproteobacteria,2K1P2@204457|Sphingomonadales 204457|Sphingomonadales U MotA TolQ ExbB proton channel exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB PJD2_k127_3136960_9 314225.ELI_13755 1.194e-81 276.0 COG0810@1|root,COG0810@2|Bacteria,1RCAG@1224|Proteobacteria,2U664@28211|Alphaproteobacteria,2K187@204457|Sphingomonadales 204457|Sphingomonadales M Periplasmic protein TonB, links inner and outer membranes - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C PJD2_k127_3136960_7 1248917.ANFX01000019_gene2392 1.072e-96 324.0 2CJQX@1|root,342E0@2|Bacteria,1RA7X@1224|Proteobacteria,2U5C1@28211|Alphaproteobacteria,2KDDU@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3136960_1 1219035.NT2_04_04470 6.547e-197 623.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,2K2BW@204457|Sphingomonadales 204457|Sphingomonadales E homoserine dehydrogenase thrA - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 PJD2_k127_3136960_12 158500.BV97_05104 1.547e-16 89.0 29Z44@1|root,30M1R@2|Bacteria,1NJK2@1224|Proteobacteria,2UKAH@28211|Alphaproteobacteria,2K854@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3136960_3 685035.ADAE01000023_gene1691 2.124e-178 565.0 COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,2JZUH@204457|Sphingomonadales 204457|Sphingomonadales G in Escherichia coli this protein forms a dimer and binds manganese glpX - 3.1.3.11,3.1.3.37 ko:K11532 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R01845,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX PJD2_k127_3136960_5 1280950.HJO_01155 1.501e-119 417.0 COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,2TSTP@28211|Alphaproteobacteria,43XWY@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short PJD2_k127_3136960_2 1479239.JQMU01000001_gene1506 1.603e-179 565.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,2K0MQ@204457|Sphingomonadales 204457|Sphingomonadales F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N PJD2_k127_3136960_4 1096930.L284_03785 9.56e-127 409.0 COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,2K0WC@204457|Sphingomonadales 204457|Sphingomonadales G COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family - - - - - - - - - - - - Inositol_P PJD2_k127_3136960_11 314225.ELI_12100 1.463e-39 156.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Sulfatase PJD2_k127_3184502_0 1219035.NT2_02_05010 5.429e-292 902.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2K2HN@204457|Sphingomonadales 204457|Sphingomonadales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom PJD2_k127_3184502_11 161528.ED21_29701 4.472e-21 96.0 2FC5G@1|root,3449A@2|Bacteria,1NB1K@1224|Proteobacteria,2UFY7@28211|Alphaproteobacteria,2K6YG@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3184502_10 1379701.JPJC01000242_gene1047 1.766e-42 178.0 COG2207@1|root,COG2207@2|Bacteria,1RAXU@1224|Proteobacteria,2U682@28211|Alphaproteobacteria,2K33E@204457|Sphingomonadales 204457|Sphingomonadales K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 PJD2_k127_3184502_5 291985.CCSI01000005_gene960 2.365e-147 485.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria,2K01W@204457|Sphingomonadales 204457|Sphingomonadales S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 PJD2_k127_3184502_8 517722.AEUE01000004_gene1142 6.269e-95 319.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,2K1G1@204457|Sphingomonadales 204457|Sphingomonadales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm PJD2_k127_3184502_6 383381.EH30_04740 3.795e-114 374.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,2K1QM@204457|Sphingomonadales 204457|Sphingomonadales U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 PJD2_k127_3184502_2 517722.AEUE01000004_gene1144 1.112e-238 752.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,2K0KU@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the GPI family pgi GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI PJD2_k127_3184502_1 1449076.JOOE01000003_gene3336 4.766e-240 757.0 COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K01C@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9,Response_reg PJD2_k127_3184502_4 1479239.JQMU01000001_gene352 4.771e-186 595.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2K0U4@204457|Sphingomonadales 204457|Sphingomonadales L DEAD DEAH box helicase - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C PJD2_k127_3184502_9 1537715.JQFJ01000002_gene1806 3.164e-60 217.0 2EWUS@1|root,33Q6B@2|Bacteria,1NTT6@1224|Proteobacteria,2VEGE@28211|Alphaproteobacteria,2KB1K@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3184502_3 1096930.L284_23200 7.033e-230 717.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2K11W@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim PJD2_k127_3184502_7 291985.CCSI01000005_gene968 5.142e-100 332.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2K2VI@204457|Sphingomonadales 204457|Sphingomonadales GM NAD(P)H-binding - - - - - - - - - - - - Epimerase PJD2_k127_3233615_11 158500.BV97_00678 2.124e-18 87.0 2AITV@1|root,319AX@2|Bacteria,1PARE@1224|Proteobacteria,2UZ6P@28211|Alphaproteobacteria,2KBW7@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3233615_1 1144305.PMI02_02055 5.282e-239 756.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2U08D@28211|Alphaproteobacteria,2KD2V@204457|Sphingomonadales 204457|Sphingomonadales E Prolyl oligopeptidase - - - - - - - - - - - - Peptidase_S9 PJD2_k127_3233615_4 1122970.AUHC01000001_gene412 5.09e-116 376.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,2K0KZ@204457|Sphingomonadales 204457|Sphingomonadales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 PJD2_k127_3233615_8 314225.ELI_05625 1.278e-36 147.0 COG1605@1|root,COG1605@2|Bacteria,1N4KD@1224|Proteobacteria,2UFR2@28211|Alphaproteobacteria,2K65F@204457|Sphingomonadales 204457|Sphingomonadales E chorismate mutase - - 4.2.99.21 ko:K04782 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R06602 RC01549,RC02148 ko00000,ko00001,ko01000 - - - CM_2 PJD2_k127_3233615_5 291985.CCSI01000001_gene2208 3.411e-115 375.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,2JZUG@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - - ko:K02533 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,SpoU_methylase PJD2_k127_3233615_6 1248917.ANFX01000008_gene346 8.79e-81 271.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2U75W@28211|Alphaproteobacteria,2K3W4@204457|Sphingomonadales 204457|Sphingomonadales K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone PJD2_k127_3233615_10 1248917.ANFX01000008_gene345 4.937e-23 101.0 2CK7K@1|root,301DG@2|Bacteria,1N7CB@1224|Proteobacteria,2UH47@28211|Alphaproteobacteria,2K78N@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3233615_0 291985.CCSI01000001_gene2211 2.306e-242 760.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2TQKT@28211|Alphaproteobacteria,2K0BB@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT PJD2_k127_3233615_7 291985.CCSI01000001_gene2212 2.926e-71 247.0 COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,2U94R@28211|Alphaproteobacteria,2K4KN@204457|Sphingomonadales 204457|Sphingomonadales G Ribose 5-phosphate isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB PJD2_k127_3233615_9 627192.SLG_00210 3.542e-29 124.0 COG0784@1|root,COG0784@2|Bacteria,1N70P@1224|Proteobacteria,2UF5P@28211|Alphaproteobacteria,2K639@204457|Sphingomonadales 204457|Sphingomonadales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg PJD2_k127_3233615_3 627192.SLG_00220 5.056e-187 597.0 COG3920@1|root,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria,2TWG0@28211|Alphaproteobacteria,2K2UT@204457|Sphingomonadales 204457|Sphingomonadales T HWE histidine kinase - - - - - - - - - - - - HWE_HK,PAS_4 PJD2_k127_3233615_2 383381.EH30_05610 4.804e-236 732.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,2K260@204457|Sphingomonadales 204457|Sphingomonadales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 PJD2_k127_3257536_5 314225.ELI_06465 4.49e-29 117.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2UCIP@28211|Alphaproteobacteria,2K5YU@204457|Sphingomonadales 204457|Sphingomonadales U Preprotein translocase subunit SecG secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG PJD2_k127_3257536_3 383381.EH30_06355 2.175e-115 376.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,2K1PI@204457|Sphingomonadales 204457|Sphingomonadales G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM PJD2_k127_3257536_1 314225.ELI_06480 1.587e-202 649.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,2K0KV@204457|Sphingomonadales 204457|Sphingomonadales O peptidylprolyl isomerase - - 5.2.1.8 ko:K01802,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,SurA_N_3 PJD2_k127_3257536_0 685778.AORL01000021_gene1088 2.733e-219 692.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,2K00K@204457|Sphingomonadales 204457|Sphingomonadales E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind PJD2_k127_3257536_4 685035.ADAE01000018_gene484 6.258e-103 342.0 COG3698@1|root,COG3698@2|Bacteria,1NH9S@1224|Proteobacteria,2TT5B@28211|Alphaproteobacteria,2K46M@204457|Sphingomonadales 204457|Sphingomonadales S Phosphodiester glycosidase - - - - - - - - - - - - NAGPA PJD2_k127_3257536_2 314225.ELI_06495 5.094e-132 426.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2TS53@28211|Alphaproteobacteria,2K07Z@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the peptidase S33 family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 PJD2_k127_3264112_1 314225.ELI_08335 1.03e-151 484.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,2K1FE@204457|Sphingomonadales 204457|Sphingomonadales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh PJD2_k127_3264112_2 314225.ELI_08340 2.394e-76 260.0 COG1381@1|root,COG1381@2|Bacteria,1MVEJ@1224|Proteobacteria,2TTYW@28211|Alphaproteobacteria,2K120@204457|Sphingomonadales 204457|Sphingomonadales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N PJD2_k127_3264112_0 1114964.L485_11740 0.0 1003.0 COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,2TSG9@28211|Alphaproteobacteria,2K1IE@204457|Sphingomonadales 204457|Sphingomonadales P Serves to protect cells from the toxic effects of hydrogen peroxide - - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel PJD2_k127_3265707_0 383381.EH30_07610 3.88e-254 788.0 COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,2TQWD@28211|Alphaproteobacteria,2K05F@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the isocitrate and isopropylmalate dehydrogenases family icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh PJD2_k127_3265707_7 314225.ELI_07690 9.885e-60 208.0 COG2204@1|root,COG2204@2|Bacteria,1RD1D@1224|Proteobacteria,2U76U@28211|Alphaproteobacteria,2KE99@204457|Sphingomonadales 204457|Sphingomonadales T cheY-homologous receiver domain - - - ko:K13589 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg PJD2_k127_3265707_6 279238.Saro_1288 2.755e-104 351.0 COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria,2K41R@204457|Sphingomonadales 204457|Sphingomonadales E N-formylglutamate amidohydrolase - - - - - - - - - - - - FGase PJD2_k127_3265707_5 314225.ELI_07680 6.835e-113 370.0 COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2U2IQ@28211|Alphaproteobacteria,2K0P1@204457|Sphingomonadales 204457|Sphingomonadales S SapC - - - - - - - - - - - - SapC PJD2_k127_3265707_1 158500.BV97_01057 4.873e-219 689.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,2K0VP@204457|Sphingomonadales 204457|Sphingomonadales C FAD linked - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 PJD2_k127_3265707_8 1479239.JQMU01000001_gene252 2.028e-40 156.0 2AM8F@1|root,31C39@2|Bacteria,1N008@1224|Proteobacteria,2UCNF@28211|Alphaproteobacteria,2K748@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3265707_2 1479239.JQMU01000001_gene251 1.048e-210 689.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2K0CY@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the DEAD box helicase family - - - - - - - - - - - - DEAD,Helicase_C PJD2_k127_3265707_3 1040986.ATYO01000005_gene6288 6.659e-151 490.0 COG0557@1|root,COG0557@2|Bacteria,1R4RK@1224|Proteobacteria,2TTRC@28211|Alphaproteobacteria 28211|Alphaproteobacteria K RNB - - - - - - - - - - - - RNB PJD2_k127_3265707_4 1219035.NT2_02_04100 1.023e-135 435.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,2K04E@204457|Sphingomonadales 204457|Sphingomonadales L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C PJD2_k127_3288064_3 1096930.L284_07855 5.135e-137 447.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2TSAV@28211|Alphaproteobacteria,2K048@204457|Sphingomonadales 204457|Sphingomonadales S modulator of DNA gyrase pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD PJD2_k127_3288064_6 1096930.L284_07850 1.706e-36 142.0 2AMZ5@1|root,31CWB@2|Bacteria,1N5R3@1224|Proteobacteria,2UDB9@28211|Alphaproteobacteria,2K669@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3288064_2 1044.EH31_11855 8.534e-141 455.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,2K0YX@204457|Sphingomonadales 204457|Sphingomonadales S ABC-type (Unclassified) transport system, ATPase component - - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C PJD2_k127_3288064_0 279238.Saro_0297 5.397e-202 638.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,2K182@204457|Sphingomonadales 204457|Sphingomonadales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD PJD2_k127_3288064_1 237727.NAP1_11908 4.13e-146 464.0 COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,2K0S8@204457|Sphingomonadales 204457|Sphingomonadales T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ctrA - - ko:K13584 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C PJD2_k127_3288064_4 1219035.NT2_05_01200 1.028e-125 409.0 COG0730@1|root,COG0730@2|Bacteria,1PGTZ@1224|Proteobacteria,2U5IZ@28211|Alphaproteobacteria,2K1II@204457|Sphingomonadales 204457|Sphingomonadales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE PJD2_k127_3288064_5 161528.ED21_20514 9.751e-77 258.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,2K0BM@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 PJD2_k127_3304099_6 237727.NAP1_04130 5.734e-110 365.0 COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2TTU7@28211|Alphaproteobacteria,2K1IX@204457|Sphingomonadales 204457|Sphingomonadales S peptidase M48, Ste24p - - - - - - - - - - - - LysM,Peptidase_M48 PJD2_k127_3304099_4 314225.ELI_04990 6.234e-158 516.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria,2K0BW@204457|Sphingomonadales 204457|Sphingomonadales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA PJD2_k127_3304099_5 1219035.NT2_02_04840 1.23e-129 419.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,2K25K@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the 'phage' integrase family xerC - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase PJD2_k127_3304099_1 1219035.NT2_02_04850 4.336e-205 656.0 2BWFC@1|root,33R2I@2|Bacteria,1R42X@1224|Proteobacteria,2U4BF@28211|Alphaproteobacteria,2K0XT@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3304099_7 1248916.ANFY01000003_gene633 2.836e-51 198.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,2K4PP@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI PJD2_k127_3304099_3 161528.ED21_26158 1.806e-161 516.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2K0HR@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase PJD2_k127_3304099_2 314225.ELI_04960 1.132e-161 509.0 COG1878@1|root,COG1878@2|Bacteria,1MV8S@1224|Proteobacteria,2TSUJ@28211|Alphaproteobacteria,2K01S@204457|Sphingomonadales 204457|Sphingomonadales S Putative cyclase - - - - - - - - - - - - Cyclase PJD2_k127_3304099_10 161528.ED21_26148 5.33e-30 122.0 2ABDV@1|root,310UN@2|Bacteria,1PAC1@1224|Proteobacteria,2UW5V@28211|Alphaproteobacteria,2KBGP@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3304099_8 279238.Saro_1898 1.284e-48 184.0 COG5483@1|root,COG5483@2|Bacteria,1N3XQ@1224|Proteobacteria,2UCV7@28211|Alphaproteobacteria,2K4V4@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 PJD2_k127_3304099_9 1219035.NT2_02_04880 2.022e-47 188.0 COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,2U9AH@28211|Alphaproteobacteria,2K52N@204457|Sphingomonadales 204457|Sphingomonadales J Putative tRNA binding domain csaA - - ko:K06878 - - - - ko00000 - - - tRNA_bind PJD2_k127_3304099_0 1537715.JQFJ01000002_gene398 4.567e-311 960.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2K050@204457|Sphingomonadales 204457|Sphingomonadales I acetyl propionyl-CoA carboxylase, alpha subunit pccA - 6.4.1.3 ko:K01965 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 PJD2_k127_3305530_2 84531.JMTZ01000014_gene2777 3.886e-92 312.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1X3WS@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N PJD2_k127_3305530_0 935863.AWZR01000001_gene1874 1.03e-157 501.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1X3U6@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt PJD2_k127_3305530_1 84531.JMTZ01000014_gene2775 4.55e-106 345.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1X31U@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N PJD2_k127_3343248_0 314225.ELI_11465 0.0 1429.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,2K1B6@204457|Sphingomonadales 204457|Sphingomonadales CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg PJD2_k127_3343248_3 279238.Saro_3146 1.321e-83 282.0 COG1309@1|root,COG1309@2|Bacteria,1RE97@1224|Proteobacteria,2U8N9@28211|Alphaproteobacteria,2K3XR@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - - - - - - - - - - TetR_N PJD2_k127_3343248_1 1537715.JQFJ01000002_gene2059 0.0 1185.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2TTFY@28211|Alphaproteobacteria,2K075@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec PJD2_k127_3343248_2 685035.ADAE01000002_gene2304 1.499e-113 368.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2TSDM@28211|Alphaproteobacteria,2JZVF@204457|Sphingomonadales 204457|Sphingomonadales F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase PJD2_k127_3348863_0 161528.ED21_20804 3.375e-271 840.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,2K1CM@204457|Sphingomonadales 204457|Sphingomonadales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 PJD2_k127_3348863_17 517722.AEUE01000002_gene2296 3.912e-22 104.0 2AKFD@1|root,31B6Y@2|Bacteria,1NYH9@1224|Proteobacteria,2UTWZ@28211|Alphaproteobacteria,2KAMQ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3348863_18 1037409.BJ6T_37600 2.235e-12 74.0 COG3631@1|root,COG3631@2|Bacteria,1RGPW@1224|Proteobacteria,2U7SR@28211|Alphaproteobacteria,3JZ78@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SnoaL-like domain - - - ko:K06893 - - - - ko00000 - - - SnoaL_2 PJD2_k127_3348863_5 1219035.NT2_04_00600 4.444e-159 507.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,2K107@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the acetylglutamate kinase family. ArgB subfamily argB - 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase PJD2_k127_3348863_16 1248917.ANFX01000018_gene2292 5.867e-26 109.0 COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,2K6UW@204457|Sphingomonadales 204457|Sphingomonadales S integral membrane protein - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT PJD2_k127_3348863_8 279238.Saro_3300 9.178e-126 414.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,2K03K@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C PJD2_k127_3348863_14 1144305.PMI02_05240 1.525e-43 167.0 2ANEF@1|root,31DD2@2|Bacteria,1RHST@1224|Proteobacteria,2UA6U@28211|Alphaproteobacteria,2K5G6@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3348863_10 1044.EH31_14870 1.374e-84 289.0 COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U59A@28211|Alphaproteobacteria,2K0G8@204457|Sphingomonadales 204457|Sphingomonadales U UPF0056 membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC PJD2_k127_3348863_9 314225.ELI_11515 1.868e-94 314.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,2K0QK@204457|Sphingomonadales 204457|Sphingomonadales S to the N-terminal domain of Lon protease - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg PJD2_k127_3348863_7 279238.Saro_0266 4.157e-130 424.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria,2K0HB@204457|Sphingomonadales 204457|Sphingomonadales O Thioredoxin - - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_15,TPR_19,TPR_20,Thioredoxin PJD2_k127_3348863_19 1087481.AGFX01000016_gene2872 0.0001219 48.0 2AWWR@1|root,31NU9@2|Bacteria,1TZQA@1239|Firmicutes,4I8ZQ@91061|Bacilli,270SK@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - PJD2_k127_3348863_2 314225.ELI_11505 1.081e-221 707.0 COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,2TW3Y@28211|Alphaproteobacteria,2KEA5@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec PJD2_k127_3348863_13 1120705.FG95_03201 1.955e-45 174.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,2UCYS@28211|Alphaproteobacteria,2K5W4@204457|Sphingomonadales 204457|Sphingomonadales S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX PJD2_k127_3348863_3 314225.ELI_11495 5.992e-204 642.0 COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2TV1G@28211|Alphaproteobacteria,2K2KQ@204457|Sphingomonadales 204457|Sphingomonadales S Saccharopine dehydrogenase NADP binding domain - - - - - - - - - - - - Sacchrp_dh_NADP PJD2_k127_3348863_1 1090320.KB900605_gene2838 1.778e-239 755.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2K1PS@204457|Sphingomonadales 204457|Sphingomonadales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N PJD2_k127_3348863_15 279238.Saro_0032 3.971e-30 127.0 COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,2K4M2@204457|Sphingomonadales 204457|Sphingomonadales C Cytochrome c - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C PJD2_k127_3348863_11 291985.CCSI01000007_gene475 6.705e-59 211.0 2BYSU@1|root,32R3U@2|Bacteria,1MZ0R@1224|Proteobacteria,2U9AE@28211|Alphaproteobacteria,2K44Z@204457|Sphingomonadales 204457|Sphingomonadales S Lipid A 3-O-deacylase (PagL) - - - - - - - - - - - - PagL PJD2_k127_3348863_6 1122970.AUHC01000002_gene1279 1.31e-154 503.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,2K152@204457|Sphingomonadales 204457|Sphingomonadales V Na -driven multidrug efflux pump - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE PJD2_k127_3348863_12 383381.EH30_12060 5.544e-47 171.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,2K539@204457|Sphingomonadales 204457|Sphingomonadales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 PJD2_k127_3348863_4 383381.EH30_12065 1.439e-181 571.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,2K0H3@204457|Sphingomonadales 204457|Sphingomonadales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 PJD2_k127_3354765_3 1122970.AUHC01000002_gene1309 1.098e-79 267.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria,2K4IV@204457|Sphingomonadales 204457|Sphingomonadales I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas PJD2_k127_3354765_2 314225.ELI_12105 2.976e-190 606.0 COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2TT7I@28211|Alphaproteobacteria,2JZV1@204457|Sphingomonadales 204457|Sphingomonadales M COG3307 Lipid A core - O-antigen ligase and related enzymes - - - - - - - - - - - - Wzy_C PJD2_k127_3354765_1 314225.ELI_12115 3.213e-199 627.0 COG0438@1|root,COG0438@2|Bacteria,1PDR7@1224|Proteobacteria,2U1R4@28211|Alphaproteobacteria,2K0MZ@204457|Sphingomonadales 204457|Sphingomonadales M Glycosyl transferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1 PJD2_k127_3354765_4 1219035.NT2_04_01440 2.316e-25 121.0 2APEI@1|root,31EH6@2|Bacteria,1NPRX@1224|Proteobacteria,2UMG0@28211|Alphaproteobacteria,2K7QP@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3354765_0 314225.ELI_12125 1.377e-210 659.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,2K19P@204457|Sphingomonadales 204457|Sphingomonadales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase PJD2_k127_337881_2 314225.ELI_10335 2.161e-140 484.0 2DBMQ@1|root,2Z9ZP@2|Bacteria,1QVZU@1224|Proteobacteria,2U5JS@28211|Alphaproteobacteria,2K406@204457|Sphingomonadales 204457|Sphingomonadales S Conserved TM helix - - - - - - - - - - - - TM_helix PJD2_k127_337881_6 1123269.NX02_04130 1.951e-43 170.0 COG0671@1|root,COG0671@2|Bacteria,1RIRR@1224|Proteobacteria,2VGCJ@28211|Alphaproteobacteria,2KE2Z@204457|Sphingomonadales 204457|Sphingomonadales I Acid phosphatase homologues - - - - - - - - - - - - PAP2 PJD2_k127_337881_4 314225.ELI_10330 3.129e-122 400.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,2TU8K@28211|Alphaproteobacteria,2K0JU@204457|Sphingomonadales 204457|Sphingomonadales E Asparaginase - - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 PJD2_k127_337881_7 317655.Sala_2746 1.874e-29 124.0 2CVK5@1|root,32SXS@2|Bacteria,1N0ZG@1224|Proteobacteria,2UCR3@28211|Alphaproteobacteria,2K6N7@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_337881_5 237727.NAP1_10818 1.093e-109 366.0 COG1714@1|root,COG1714@2|Bacteria,1RAZN@1224|Proteobacteria,2U6W9@28211|Alphaproteobacteria,2K24C@204457|Sphingomonadales 204457|Sphingomonadales S RDD family - - - - - - - - - - - - RDD PJD2_k127_337881_3 1122970.AUHC01000015_gene2530 2.896e-137 449.0 COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,2U06S@28211|Alphaproteobacteria,2JZZD@204457|Sphingomonadales 204457|Sphingomonadales S membrane - - - - - - - - - - - - SpoIIM PJD2_k127_337881_0 1219035.NT2_05_01490 2.379e-179 586.0 COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,2TU87@28211|Alphaproteobacteria,2K038@204457|Sphingomonadales 204457|Sphingomonadales S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 PJD2_k127_337881_1 1122970.AUHC01000015_gene2528 9.69e-156 497.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,2K1NZ@204457|Sphingomonadales 204457|Sphingomonadales S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 PJD2_k127_3378851_0 1449076.JOOE01000001_gene2177 0.0 1042.0 COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2TQJW@28211|Alphaproteobacteria,2K376@204457|Sphingomonadales 204457|Sphingomonadales C Respiratory nitrate reductase alpha N-terminal - - - - - - - - - - - - Molybdopterin,Molydop_binding,Nitr_red_alph_N PJD2_k127_3395714_0 291985.CCSI01000005_gene956 2.108e-156 498.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,2K08N@204457|Sphingomonadales 204457|Sphingomonadales LU Rossmann fold nucleotide-binding protein involved in DNA uptake dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A PJD2_k127_3395714_2 279238.Saro_1802 1.094e-24 107.0 2E5ES@1|root,3306N@2|Bacteria,1N5VN@1224|Proteobacteria,2UD42@28211|Alphaproteobacteria,2KBZT@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3395714_1 1248917.ANFX01000041_gene1741 7.134e-117 377.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2K2HN@204457|Sphingomonadales 204457|Sphingomonadales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom PJD2_k127_3498579_0 1219035.NT2_02_03910 1.309e-118 398.0 COG2911@1|root,COG2911@2|Bacteria,1R4BU@1224|Proteobacteria,2TSKR@28211|Alphaproteobacteria,2K0MI@204457|Sphingomonadales 204457|Sphingomonadales S Dicarboxylate transport - - - - - - - - - - - - DctA-YdbH PJD2_k127_3498579_1 314225.ELI_07560 4.364e-73 254.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria,2K0WQ@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC PJD2_k127_3526497_1 314225.ELI_13055 5.175e-48 173.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,2K05A@204457|Sphingomonadales 204457|Sphingomonadales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc PJD2_k127_3526497_0 1122970.AUHC01000010_gene1620 3.686e-160 526.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,2K0HT@204457|Sphingomonadales 204457|Sphingomonadales J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N PJD2_k127_3526497_2 291985.CCSI01000002_gene1429 1.485e-33 133.0 2EMU4@1|root,33FGG@2|Bacteria,1NNB6@1224|Proteobacteria,2UMJV@28211|Alphaproteobacteria,2K6U1@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3526497_3 1219035.NT2_04_03490 2.787e-32 130.0 COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2U1D8@28211|Alphaproteobacteria,2K0IT@204457|Sphingomonadales 204457|Sphingomonadales Q dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH PJD2_k127_3530443_1 161528.ED21_29226 4.069e-128 412.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2TSKQ@28211|Alphaproteobacteria,2K0JN@204457|Sphingomonadales 204457|Sphingomonadales F Belongs to the phosphoglycerate kinase family pgk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK PJD2_k127_3530443_0 1479239.JQMU01000001_gene2564 1.378e-192 604.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TR6E@28211|Alphaproteobacteria,2K0GC@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N PJD2_k127_3539331_3 1096930.L284_03705 3.94e-123 402.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,2K0I4@204457|Sphingomonadales 204457|Sphingomonadales E acetylornithine aminotransferase argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 PJD2_k127_3539331_4 237727.NAP1_12208 6.195e-107 354.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2JZZ2@204457|Sphingomonadales 204457|Sphingomonadales K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD PJD2_k127_3539331_2 161528.ED21_20189 1.273e-134 432.0 COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2TTT6@28211|Alphaproteobacteria,2K1P9@204457|Sphingomonadales 204457|Sphingomonadales P COG0861 Membrane protein TerC, possibly involved in tellurium resistance - - - - - - - - - - - - TerC PJD2_k127_3539331_5 314225.ELI_13900 5.651e-48 187.0 COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2UD2M@28211|Alphaproteobacteria,2K56H@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF442 PJD2_k127_3539331_6 279238.Saro_3144 3.451e-43 169.0 2CM6U@1|root,2ZRQ1@2|Bacteria,1NDYF@1224|Proteobacteria,2UHHI@28211|Alphaproteobacteria,2K7EW@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3539331_1 291985.CCSI01000002_gene1286 2.731e-172 544.0 COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,2TT68@28211|Alphaproteobacteria,2K2GA@204457|Sphingomonadales 204457|Sphingomonadales I sterol desaturase - - - - - - - - - - - - FA_hydroxylase PJD2_k127_3539331_0 317655.Sala_2331 4.77e-275 854.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2K0FF@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the GMC oxidoreductase family - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N,Lycopene_cycl PJD2_k127_3539331_7 1248916.ANFY01000009_gene246 1.817e-38 152.0 2AKNV@1|root,31BFG@2|Bacteria,1NZ2P@1224|Proteobacteria,2USTH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - DUF3237 PJD2_k127_3544644_0 314225.ELI_01645 0.0 1269.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2K0C4@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB PJD2_k127_3544644_9 161528.ED21_30879 1.862e-34 148.0 COG2335@1|root,COG2335@2|Bacteria,1P0TK@1224|Proteobacteria,2UUXR@28211|Alphaproteobacteria,2KB4X@204457|Sphingomonadales 204457|Sphingomonadales M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin PJD2_k127_3544644_6 291985.CCSI01000003_gene41 5.869e-72 255.0 29ZIU@1|root,30MJ0@2|Bacteria,1RF6K@1224|Proteobacteria,2U8DV@28211|Alphaproteobacteria,2K50U@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3544644_5 1219035.NT2_05_03750 1.52e-78 268.0 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7X4@28211|Alphaproteobacteria,2K9AH@204457|Sphingomonadales 204457|Sphingomonadales G lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme PJD2_k127_3544644_11 279238.Saro_2310 7.964e-23 104.0 COG0727@1|root,COG0727@2|Bacteria,1NJH8@1224|Proteobacteria,2UYUX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative zinc- or iron-chelating domain - - - - - - - - - - - - CxxCxxCC PJD2_k127_3544644_1 517722.AEUE01000004_gene771 2.017e-286 882.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,2K06N@204457|Sphingomonadales 204457|Sphingomonadales E highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N PJD2_k127_3544644_7 383381.EH30_01735 7.225e-59 206.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,2K4IQ@204457|Sphingomonadales 204457|Sphingomonadales K Belongs to the P(II) protein family glnB - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II PJD2_k127_3544644_4 1219035.NT2_05_03790 7.782e-138 450.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,2K2G3@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh PJD2_k127_3544644_10 1479239.JQMU01000001_gene2275 5.312e-34 134.0 COG0791@1|root,COG0791@2|Bacteria,1PDUD@1224|Proteobacteria,2VA22@28211|Alphaproteobacteria,2K74U@204457|Sphingomonadales 204457|Sphingomonadales M NLP P60 protein - - - - - - - - - - - - - PJD2_k127_3544644_2 161528.ED21_30839 4.063e-241 754.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,2JZV7@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the peptidase M17 family - - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 PJD2_k127_3544644_8 314225.ELI_01685 2.055e-56 211.0 2ANQE@1|root,31DQ0@2|Bacteria,1MWJD@1224|Proteobacteria,2U7P7@28211|Alphaproteobacteria,2K5A1@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function (DUF4163) - - - - - - - - - - - - DUF4163 PJD2_k127_3544644_3 1219035.NT2_05_03830 4.585e-141 449.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,2K0AR@204457|Sphingomonadales 204457|Sphingomonadales E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 PJD2_k127_3576128_3 314225.ELI_01045 9.411e-23 98.0 COG3087@1|root,COG5010@1|root,COG3087@2|Bacteria,COG5010@2|Bacteria,1RK9P@1224|Proteobacteria,2U5CI@28211|Alphaproteobacteria,2K119@204457|Sphingomonadales 204457|Sphingomonadales U Sporulation related domain - - - - - - - - - - - - SPOR,TPR_16,TPR_19,TPR_4 PJD2_k127_3576128_1 1219035.NT2_05_02850 1.654e-193 612.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2TSTM@28211|Alphaproteobacteria,2K003@204457|Sphingomonadales 204457|Sphingomonadales F dihydroorotase - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 PJD2_k127_3576128_2 291985.CCSI01000003_gene157 7.681e-186 585.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2TRHP@28211|Alphaproteobacteria,2K0IH@204457|Sphingomonadales 204457|Sphingomonadales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N PJD2_k127_3576128_0 685035.ADAE01000004_gene1941 1.339e-211 667.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TSXA@28211|Alphaproteobacteria,2K1TY@204457|Sphingomonadales 204457|Sphingomonadales OU signal peptide peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 PJD2_k127_3636784_0 1122970.AUHC01000005_gene1915 4.972e-304 972.0 COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,2U0S5@28211|Alphaproteobacteria,2K0JT@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_3636784_3 314225.ELI_02455 3.057e-120 392.0 COG1597@1|root,COG1597@2|Bacteria,1RIPU@1224|Proteobacteria,2UHBV@28211|Alphaproteobacteria 28211|Alphaproteobacteria I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - - - - - - - - - - DAGK_cat PJD2_k127_3636784_1 685035.ADAE01000018_gene962 5.996e-152 484.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TR8D@28211|Alphaproteobacteria,2K0D0@204457|Sphingomonadales 204457|Sphingomonadales F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt PJD2_k127_3636784_4 983920.Y88_0968 3.159e-114 375.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2K0QB@204457|Sphingomonadales 204457|Sphingomonadales T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C PJD2_k127_3636784_5 383381.EH30_05320 1.138e-101 348.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2TQMN@28211|Alphaproteobacteria,2K0AA@204457|Sphingomonadales 204457|Sphingomonadales P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU PJD2_k127_3636784_2 291985.CCSI01000001_gene2656 9.391e-139 452.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,2JZZN@204457|Sphingomonadales 204457|Sphingomonadales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran PJD2_k127_3636784_6 1193729.A1OE_1063 3.712e-65 226.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,2JQA8@204441|Rhodospirillales 204441|Rhodospirillales P Phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 PJD2_k127_3638804_5 1044.EH31_02570 2.772e-36 139.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2U1E2@28211|Alphaproteobacteria,2K08I@204457|Sphingomonadales 204457|Sphingomonadales M Chain-length determining protein - - - - - - - - - - - - GNVR,Wzz PJD2_k127_3638804_3 1144305.PMI02_00189 1.832e-104 344.0 COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2U835@28211|Alphaproteobacteria,2K15P@204457|Sphingomonadales 204457|Sphingomonadales M polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB PJD2_k127_3638804_1 1122970.AUHC01000001_gene618 2.66e-198 624.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TUK2@28211|Alphaproteobacteria,2K0RW@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the Orn Lys Arg decarboxylase class-II family - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC PJD2_k127_3638804_0 314225.ELI_06870 2.121e-234 734.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TRP2@28211|Alphaproteobacteria,2K0DK@204457|Sphingomonadales 204457|Sphingomonadales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C PJD2_k127_3638804_2 1122970.AUHC01000001_gene620 1.459e-128 419.0 COG5653@1|root,COG5653@2|Bacteria,1RDJC@1224|Proteobacteria,2U32H@28211|Alphaproteobacteria,2K270@204457|Sphingomonadales 204457|Sphingomonadales M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 PJD2_k127_3638804_6 161528.ED21_28158 4.162e-36 141.0 COG0236@1|root,COG0236@2|Bacteria,1N83X@1224|Proteobacteria,2UFBF@28211|Alphaproteobacteria,2K6WR@204457|Sphingomonadales 204457|Sphingomonadales IQ acyl carrier protein - - - - - - - - - - - - PP-binding PJD2_k127_3638804_4 685035.ADAE01000018_gene408 1.572e-77 266.0 COG2267@1|root,COG2267@2|Bacteria,1RJMW@1224|Proteobacteria,2UB7N@28211|Alphaproteobacteria,2K5KA@204457|Sphingomonadales 204457|Sphingomonadales I carboxylic ester hydrolase activity - - - - - - - - - - - - - PJD2_k127_3638804_7 314225.ELI_06890 3.467e-28 115.0 COG1073@1|root,COG1073@2|Bacteria,1R61B@1224|Proteobacteria,2U45E@28211|Alphaproteobacteria,2K10H@204457|Sphingomonadales 204457|Sphingomonadales S TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 PJD2_k127_3640618_7 291985.CCSI01000002_gene1400 1.25e-88 295.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,2K115@204457|Sphingomonadales 204457|Sphingomonadales C NADPH quinone - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 PJD2_k127_3640618_5 1088721.NSU_1727 2.012e-98 326.0 COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TR9W@28211|Alphaproteobacteria,2K0R9@204457|Sphingomonadales 204457|Sphingomonadales O Belongs to the GST superfamily - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 PJD2_k127_3640618_4 237727.NAP1_12818 2.394e-116 378.0 COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria,2K0D3@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09987 - - - - ko00000 - - - DUF1013 PJD2_k127_3640618_0 685035.ADAE01000023_gene1587 1.148e-221 700.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K001@204457|Sphingomonadales 204457|Sphingomonadales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C PJD2_k127_3640618_9 1479239.JQMU01000001_gene1392 3.093e-44 165.0 COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2U5DW@28211|Alphaproteobacteria,2K66W@204457|Sphingomonadales 204457|Sphingomonadales M Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin PJD2_k127_3640618_2 1219035.NT2_04_03800 7.188e-157 503.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2K148@204457|Sphingomonadales 204457|Sphingomonadales M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 PJD2_k127_3640618_1 1144305.PMI02_01208 4.528e-181 575.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,2K0DR@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh PJD2_k127_3640618_3 627192.SLG_33360 7.165e-138 447.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,2K1KY@204457|Sphingomonadales 204457|Sphingomonadales C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red PJD2_k127_3640618_8 1174684.EBMC1_03035 1.617e-72 256.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2U6ZC@28211|Alphaproteobacteria,2K3WB@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like PJD2_k127_3640618_6 627192.SLG_34160 4.624e-90 299.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,2K275@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rmlB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd PJD2_k127_3760116_9 314225.ELI_10445 2.008e-51 182.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2TQY2@28211|Alphaproteobacteria,2K0X4@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt PJD2_k127_3760116_6 237727.NAP1_10968 3.476e-93 315.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria,2K2JA@204457|Sphingomonadales 204457|Sphingomonadales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N PJD2_k127_3760116_11 1449076.JOOE01000004_gene444 1.357e-41 164.0 COG3791@1|root,COG3791@2|Bacteria,1N023@1224|Proteobacteria,2UC7M@28211|Alphaproteobacteria,2K6R3@204457|Sphingomonadales 204457|Sphingomonadales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA PJD2_k127_3760116_2 314225.ELI_10425 2.88e-188 595.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,2K0Y3@204457|Sphingomonadales 204457|Sphingomonadales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N PJD2_k127_3760116_12 1144305.PMI02_02486 3.324e-35 147.0 2A79B@1|root,30W5X@2|Bacteria,1RD0Q@1224|Proteobacteria,2U8HI@28211|Alphaproteobacteria,2KDJI@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3760116_0 1219035.NT2_05_01380 0.0 1525.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,2K0CP@204457|Sphingomonadales 204457|Sphingomonadales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C PJD2_k127_3760116_5 161528.ED21_20949 7.347e-106 351.0 COG0697@1|root,COG0697@2|Bacteria,1RC7K@1224|Proteobacteria,2U5C2@28211|Alphaproteobacteria,2K1KG@204457|Sphingomonadales 204457|Sphingomonadales EG of the drug metabolite transporter (DMT) superfamily - - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA PJD2_k127_3760116_3 1219035.NT2_05_01400 2.141e-175 561.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K0KA@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - YkuD PJD2_k127_3760116_7 314225.ELI_10385 5.451e-83 282.0 COG1376@1|root,COG1376@2|Bacteria,1RKB2@1224|Proteobacteria,2UAA8@28211|Alphaproteobacteria,2K57T@204457|Sphingomonadales 204457|Sphingomonadales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD_2 PJD2_k127_3760116_1 161528.ED21_20979 1.448e-211 667.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2TQSI@28211|Alphaproteobacteria,2K1FA@204457|Sphingomonadales 204457|Sphingomonadales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE PJD2_k127_3760116_4 314225.ELI_10360 1.548e-128 419.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,2U20B@28211|Alphaproteobacteria,2KD38@204457|Sphingomonadales 204457|Sphingomonadales P CorA-like Mg2+ transporter protein - - - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA PJD2_k127_3760116_8 1248917.ANFX01000014_gene1356 1.345e-59 214.0 2A20S@1|root,30QAP@2|Bacteria,1NN67@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - PJD2_k127_3760116_10 685035.ADAE01000007_gene1332 2.167e-43 164.0 COG0454@1|root,COG0456@2|Bacteria,1RI7M@1224|Proteobacteria,2UAKW@28211|Alphaproteobacteria,2K51C@204457|Sphingomonadales 204457|Sphingomonadales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 PJD2_k127_3826401_13 1219035.NT2_01_02900 5.552e-103 338.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,2JZXN@204457|Sphingomonadales 204457|Sphingomonadales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG PJD2_k127_3826401_17 291985.CCSI01000001_gene1969 2.266e-56 211.0 COG1514@1|root,COG1514@2|Bacteria,1RIHA@1224|Proteobacteria,2UAUZ@28211|Alphaproteobacteria,2K46A@204457|Sphingomonadales 204457|Sphingomonadales J 2'-5' RNA ligase superfamily - - - - - - - - - - - - 2_5_RNA_ligase2 PJD2_k127_3826401_0 279238.Saro_2567 0.0 1267.0 COG2352@1|root,COG2352@2|Bacteria,1Q2KN@1224|Proteobacteria,2VC03@28211|Alphaproteobacteria,2K11R@204457|Sphingomonadales 204457|Sphingomonadales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle - - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase PJD2_k127_3826401_10 1122612.AUBA01000002_gene1858 8.98e-150 481.0 COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,2TVK9@28211|Alphaproteobacteria,2K1K1@204457|Sphingomonadales 204457|Sphingomonadales S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 PJD2_k127_3826401_11 279238.Saro_2448 1.134e-135 451.0 COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,2U55E@28211|Alphaproteobacteria,2K0AF@204457|Sphingomonadales 204457|Sphingomonadales G Major facilitator superfamily - - - ko:K08191 - - - - ko00000,ko02000 2.A.1.14.2 - - MFS_1 PJD2_k127_3826401_2 1112212.JH584235_gene1997 4.069e-315 984.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2TYER@28211|Alphaproteobacteria,2KEM2@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_3826401_1 279238.Saro_2446 0.0 1063.0 COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2U1U0@28211|Alphaproteobacteria,2K146@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.199 ko:K15922 - - R00802,R11543 RC00028,RC00059,RC00077,RC00451 ko00000,ko01000 - GH31 - Glyco_hydro_31 PJD2_k127_3826401_6 279238.Saro_2445 3.578e-182 573.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2TRMS@28211|Alphaproteobacteria,2K12A@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 PJD2_k127_3826401_9 1248917.ANFX01000012_gene1761 1.84e-151 482.0 COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,2U0C4@28211|Alphaproteobacteria,2K2TQ@204457|Sphingomonadales 204457|Sphingomonadales S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red PJD2_k127_3826401_5 317655.Sala_1660 1.824e-219 683.0 COG2141@1|root,COG2141@2|Bacteria,1MWMV@1224|Proteobacteria,2TTIQ@28211|Alphaproteobacteria,2K0FP@204457|Sphingomonadales 204457|Sphingomonadales C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - 1.14.14.5 ko:K04091 ko00920,map00920 - R07210,R10206 RC01779,RC02556 ko00000,ko00001,ko01000 - - - Bac_luciferase PJD2_k127_3826401_4 279238.Saro_2442 2.121e-246 767.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,2K0SB@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C PJD2_k127_3826401_14 1248760.ANFZ01000009_gene790 4.793e-88 302.0 COG0431@1|root,COG0431@2|Bacteria,1RB2T@1224|Proteobacteria,2U6RE@28211|Alphaproteobacteria,2K1QH@204457|Sphingomonadales 204457|Sphingomonadales S NADPH-dependent FMN reductase - - 1.5.1.38 ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 - R05706,R07210,R10206 RC00126,RC01779,RC02556 ko00000,ko00001,ko01000 - - - FMN_red PJD2_k127_3826401_15 1248760.ANFZ01000009_gene789 2.405e-83 285.0 COG0108@1|root,COG0108@2|Bacteria,1RBRE@1224|Proteobacteria,2U6BU@28211|Alphaproteobacteria,2K4AG@204457|Sphingomonadales 204457|Sphingomonadales H 3,4-dihydroxy-2-butanone 4-phosphate synthase - - - - - - - - - - - - DHBP_synthase PJD2_k127_3826401_18 1219035.NT2_01_05680 5.124e-22 101.0 2DRHM@1|root,32UR4@2|Bacteria,1RCYI@1224|Proteobacteria,2UAAG@28211|Alphaproteobacteria,2KC6N@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3826401_12 1219035.NT2_01_05690 7.614e-127 435.0 COG3173@1|root,COG3173@2|Bacteria,1MY0Y@1224|Proteobacteria,2TRMW@28211|Alphaproteobacteria,2K1BV@204457|Sphingomonadales 204457|Sphingomonadales S Phosphotransferase enzyme family - - - - - - - - - - - - APH PJD2_k127_3826401_8 1502850.FG91_00044 1.682e-166 532.0 COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,2TR62@28211|Alphaproteobacteria,2K1KR@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 PJD2_k127_3826401_3 291985.CCSI01000007_gene507 2.257e-267 825.0 COG1960@1|root,COG1960@2|Bacteria,1MWUU@1224|Proteobacteria,2TT47@28211|Alphaproteobacteria,2K2YK@204457|Sphingomonadales 204457|Sphingomonadales I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_3826401_16 350054.Mflv_0518 5.214e-67 245.0 COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria,232BV@1762|Mycobacteriaceae 201174|Actinobacteria I hydrolase ytpA GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 PJD2_k127_3826401_7 237727.NAP1_15778 6.995e-174 547.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,2K0M5@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C PJD2_k127_3842686_7 685035.ADAE01000020_gene1443 8.81e-72 243.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TTUF@28211|Alphaproteobacteria,2K2X0@204457|Sphingomonadales 204457|Sphingomonadales I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_3842686_5 1123269.NX02_19160 7.25e-114 372.0 COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2TSNX@28211|Alphaproteobacteria,2K2M6@204457|Sphingomonadales 204457|Sphingomonadales IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 PJD2_k127_3842686_2 291985.CCSI01000008_gene1062 3.856e-174 552.0 COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,2TQYU@28211|Alphaproteobacteria,2K2VH@204457|Sphingomonadales 204457|Sphingomonadales Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase PJD2_k127_3842686_6 1122970.AUHC01000014_gene1134 3.302e-105 345.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,2K49D@204457|Sphingomonadales 204457|Sphingomonadales O maleylacetoacetate isomerase - - 5.2.1.2 ko:K01800 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181 RC00867 ko00000,ko00001,ko00002,ko01000 - - - GST_N,GST_N_3 PJD2_k127_3842686_1 314225.ELI_09200 4.984e-227 708.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,2K030@204457|Sphingomonadales 204457|Sphingomonadales I acyl-CoA dehydrogenase - - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_3842686_9 291985.CCSI01000008_gene1067 8.38e-38 145.0 COG3947@1|root,COG3947@2|Bacteria,1QUNY@1224|Proteobacteria,2TW2H@28211|Alphaproteobacteria,2K64A@204457|Sphingomonadales 204457|Sphingomonadales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg PJD2_k127_3842686_8 161528.ED21_30594 2.312e-41 174.0 COG3743@1|root,COG3743@2|Bacteria,1N76A@1224|Proteobacteria,2UFVP@28211|Alphaproteobacteria,2K4QR@204457|Sphingomonadales 204457|Sphingomonadales S rRNA binding - - - - - - - - - - - - HHH_5 PJD2_k127_3842686_0 161528.ED21_30579 6.102e-232 735.0 COG2244@1|root,COG2244@2|Bacteria,1PDRG@1224|Proteobacteria,2TVKM@28211|Alphaproteobacteria,2K0P5@204457|Sphingomonadales 204457|Sphingomonadales S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3 PJD2_k127_3842686_4 1479239.JQMU01000001_gene800 4.982e-155 501.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,2K0GB@204457|Sphingomonadales 204457|Sphingomonadales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N PJD2_k127_3842686_3 161528.ED21_30569 8.243e-163 517.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2TSF7@28211|Alphaproteobacteria,2K0S9@204457|Sphingomonadales 204457|Sphingomonadales O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 PJD2_k127_3855707_2 317655.Sala_0859 6.122e-115 374.0 COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2U3CC@28211|Alphaproteobacteria,2K36J@204457|Sphingomonadales 204457|Sphingomonadales IQ KR domain - - - - - - - - - - - - adh_short,adh_short_C2 PJD2_k127_3855707_1 1174684.EBMC1_09001 5.954e-124 403.0 COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2U1ZJ@28211|Alphaproteobacteria,2K1WR@204457|Sphingomonadales 204457|Sphingomonadales IQ KR domain - - - - - - - - - - - - adh_short_C2 PJD2_k127_3855707_0 314225.ELI_04125 0.0 1014.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,2K046@204457|Sphingomonadales 204457|Sphingomonadales L DNA ligase ligD - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N PJD2_k127_3878725_1 383381.EH30_13685 7.063e-133 424.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,2K0B0@204457|Sphingomonadales 204457|Sphingomonadales I acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans PJD2_k127_3878725_2 1248917.ANFX01000013_gene1416 4.684e-65 229.0 COG1309@1|root,COG1309@2|Bacteria,1R44G@1224|Proteobacteria,2TTF0@28211|Alphaproteobacteria,2K576@204457|Sphingomonadales 204457|Sphingomonadales K PFAM regulatory protein TetR - - - - - - - - - - - - TetR_N PJD2_k127_3878725_0 685035.ADAE01000002_gene2258 4.544e-194 621.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2TTUP@28211|Alphaproteobacteria,2K1RZ@204457|Sphingomonadales 204457|Sphingomonadales F Belongs to the 5'-nucleotidase family - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos PJD2_k127_3878725_3 291985.CCSI01000002_gene1680 8.198e-37 147.0 2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria,2UCQS@28211|Alphaproteobacteria,2K5ZN@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3881317_1 1096930.L284_14475 4.826e-184 580.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,2K00X@204457|Sphingomonadales 204457|Sphingomonadales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N PJD2_k127_3881317_0 685035.ADAE01000018_gene1153 1.258e-297 930.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2K1S8@204457|Sphingomonadales 204457|Sphingomonadales S COG2366 Protein related to penicillin acylase - - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase PJD2_k127_3881317_2 158500.BV97_00919 6.926e-55 197.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2K05M@204457|Sphingomonadales 204457|Sphingomonadales S Peptidase, M16 - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_3911174_5 383381.EH30_06235 3.578e-43 160.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2TRE6@28211|Alphaproteobacteria,2K1CX@204457|Sphingomonadales 204457|Sphingomonadales S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH PJD2_k127_3911174_2 314225.ELI_06335 3.186e-105 357.0 COG0457@1|root,COG0457@2|Bacteria,1RFBY@1224|Proteobacteria,2UB13@28211|Alphaproteobacteria,2KE87@204457|Sphingomonadales 204457|Sphingomonadales S Tetratricopeptide repeat - - - - - - - - - - - - - PJD2_k127_3911174_0 1219035.NT2_13_00420 0.0 1512.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,2K02J@204457|Sphingomonadales 204457|Sphingomonadales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV PJD2_k127_3911174_1 314225.ELI_06345 4.29e-133 429.0 COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2U38D@28211|Alphaproteobacteria,2K2C0@204457|Sphingomonadales 204457|Sphingomonadales Q taurine catabolism dioxygenase - - 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 - R05320 RC01331 ko00000,ko00001,ko01000 - - - TauD PJD2_k127_3911174_4 279238.Saro_1916 5.746e-59 218.0 COG3714@1|root,COG3714@2|Bacteria,1RFIR@1224|Proteobacteria,2U8S6@28211|Alphaproteobacteria,2K4YA@204457|Sphingomonadales 204457|Sphingomonadales S YhhN family - - - - - - - - - - - - YhhN PJD2_k127_3911174_3 555793.WSK_1117 4.729e-98 324.0 COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,2TR6M@28211|Alphaproteobacteria,2K17V@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO - 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA PJD2_k127_3917469_8 1219035.NT2_02_03350 5.428e-48 173.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,2K1FE@204457|Sphingomonadales 204457|Sphingomonadales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh PJD2_k127_3917469_2 555793.WSK_4240 2.095e-149 481.0 COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1MV8J@1224|Proteobacteria,2TTYF@28211|Alphaproteobacteria,2K22B@204457|Sphingomonadales 204457|Sphingomonadales M COG0463 Glycosyltransferases involved in cell wall biogenesis - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2,GtrA PJD2_k127_3917469_1 291985.CCSI01000005_gene975 1.056e-154 505.0 COG4346@1|root,COG4346@2|Bacteria,1QHX0@1224|Proteobacteria,2TVG5@28211|Alphaproteobacteria,2K03Y@204457|Sphingomonadales 204457|Sphingomonadales O C-terminal four TMM region of protein-O-mannosyltransferase - - 2.4.1.109 ko:K00728 ko00514,ko00515,ko01100,map00514,map00515,map01100 - R04072,R07620,R11399 RC00005,RC00059,RC00397 ko00000,ko00001,ko01000,ko01003 - GT39 - PMT,PMT_2,PMT_4TMC PJD2_k127_3917469_0 314225.ELI_08290 7.834e-218 680.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TTMF@28211|Alphaproteobacteria,2K056@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - 2.5.1.48 ko:K01739,ko:K10764 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP PJD2_k127_3917469_6 237727.NAP1_07510 1.748e-69 238.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2U9JM@28211|Alphaproteobacteria,2K4GR@204457|Sphingomonadales 204457|Sphingomonadales P protein affecting Mg2 Co2 transport apaG - - ko:K06195 - - - - ko00000 - - - DUF525 PJD2_k127_3917469_3 314225.ELI_08245 7.695e-134 430.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2U2F2@28211|Alphaproteobacteria,2K1M3@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate PJD2_k127_3917469_5 314225.ELI_08240 4.09e-71 248.0 COG0454@1|root,COG0456@2|Bacteria,1QWIU@1224|Proteobacteria,2TWYI@28211|Alphaproteobacteria,2KEG9@204457|Sphingomonadales 204457|Sphingomonadales K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 PJD2_k127_3917469_7 13689.BV96_03079 4.73e-59 209.0 2CFPU@1|root,32S27@2|Bacteria,1R3C9@1224|Proteobacteria,2U00B@28211|Alphaproteobacteria,2K4JY@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3917469_4 1096930.L284_12050 1.46e-131 439.0 28IIY@1|root,2Z8JY@2|Bacteria,1NRU9@1224|Proteobacteria,2UPN0@28211|Alphaproteobacteria,2K1IH@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3919705_16 861299.J421_2863 1.287e-39 154.0 2E3HM@1|root,32YG7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_3919705_4 517722.AEUE01000001_gene2803 6.744e-111 361.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria,2K16A@204457|Sphingomonadales 204457|Sphingomonadales F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin PJD2_k127_3919705_18 291985.CCSI01000006_gene1193 1.182e-28 122.0 2DI4F@1|root,30209@2|Bacteria,1NJ8G@1224|Proteobacteria,2UKPT@28211|Alphaproteobacteria,2KDJZ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_3919705_10 314225.ELI_09575 7.642e-85 283.0 COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria,2K35H@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09985 - - - - ko00000 - - - SspB PJD2_k127_3919705_5 291985.CCSI01000006_gene1195 8.038e-105 358.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,2K1TW@204457|Sphingomonadales 204457|Sphingomonadales E Imidazoleglycerol-phosphate dehydratase hisB - 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD PJD2_k127_3919705_7 555793.WSK_2442 9.128e-99 329.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2TTT4@28211|Alphaproteobacteria,2K223@204457|Sphingomonadales 204457|Sphingomonadales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase PJD2_k127_3919705_6 555793.WSK_1535 1.977e-103 342.0 COG4221@1|root,COG4221@2|Bacteria,1R6GB@1224|Proteobacteria,2U2PB@28211|Alphaproteobacteria,2K2UH@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short PJD2_k127_3919705_1 1449076.JOOE01000006_gene662 3.649e-191 608.0 COG2152@1|root,COG2152@2|Bacteria,1Q4YM@1224|Proteobacteria,2UI58@28211|Alphaproteobacteria,2K098@204457|Sphingomonadales 204457|Sphingomonadales G beta-1,4-mannooligosaccharide phosphorylase - - - - - - - - - - - - Glyco_hydro_130 PJD2_k127_3919705_3 1144305.PMI02_03930 2.268e-128 413.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,2K0CJ@204457|Sphingomonadales 204457|Sphingomonadales E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth PJD2_k127_3919705_2 983920.Y88_3272 4.377e-136 437.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2TQXD@28211|Alphaproteobacteria,2K1KV@204457|Sphingomonadales 204457|Sphingomonadales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF - - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth PJD2_k127_3919705_17 1219035.NT2_10_01040 2.581e-38 146.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2UBU3@28211|Alphaproteobacteria,2K5ZV@204457|Sphingomonadales 204457|Sphingomonadales E Phosphoribosyl-ATP hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH PJD2_k127_3919705_14 1479239.JQMU01000001_gene2139 2.687e-59 213.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,2K4G2@204457|Sphingomonadales 204457|Sphingomonadales FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - - - - - - - - - - HIT PJD2_k127_3919705_13 1122970.AUHC01000002_gene1499 2.454e-63 221.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2UBYM@28211|Alphaproteobacteria,2K4JS@204457|Sphingomonadales 204457|Sphingomonadales S thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 PJD2_k127_3919705_9 1219035.NT2_10_01070 1.343e-88 299.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2TQXQ@28211|Alphaproteobacteria,2K039@204457|Sphingomonadales 204457|Sphingomonadales U MotA TolQ ExbB proton channel tolQ - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB PJD2_k127_3919705_15 291985.CCSI01000006_gene1203 1.059e-53 194.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,2K53V@204457|Sphingomonadales 204457|Sphingomonadales U Biopolymer transport protein tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD PJD2_k127_3919705_11 314225.ELI_09510 2.416e-80 276.0 COG5373@1|root,COG5373@2|Bacteria,1N5K2@1224|Proteobacteria,2UB74@28211|Alphaproteobacteria,2JZY7@204457|Sphingomonadales 204457|Sphingomonadales S membrane tolA - - - - - - - - - - - - PJD2_k127_3919705_0 161528.ED21_21369 1.848e-241 758.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2K1NT@204457|Sphingomonadales 204457|Sphingomonadales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N PJD2_k127_3919705_12 314225.ELI_09500 4.104e-67 232.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,2K49Y@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA PJD2_k127_3919705_8 685035.ADAE01000008_gene2991 1.052e-92 306.0 COG0484@1|root,COG0484@2|Bacteria,1RASJ@1224|Proteobacteria,2U5FR@28211|Alphaproteobacteria,2K3W9@204457|Sphingomonadales 204457|Sphingomonadales O molecular chaperone - - - - - - - - - - - - DnaJ PJD2_k127_3937822_1 279238.Saro_3585 2.506e-71 253.0 COG0845@1|root,COG0845@2|Bacteria,1Q10W@1224|Proteobacteria,2TSC8@28211|Alphaproteobacteria,2K9U3@204457|Sphingomonadales 204457|Sphingomonadales M HlyD family secretion protein - - - ko:K02005 - - - - ko00000 - - - HlyD_3 PJD2_k127_3937822_0 279238.Saro_3584 5.379e-228 717.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD PJD2_k127_3985519_1 366602.Caul_3856 2.72e-120 404.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,2KHZV@204458|Caulobacterales 204458|Caulobacterales H MoeA N-terminal region (domain I and II) - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_N PJD2_k127_3985519_3 1121123.AUAO01000001_gene748 1.527e-88 294.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2TTA8@28211|Alphaproteobacteria,2KFN3@204458|Caulobacterales 204458|Caulobacterales H May be involved in the biosynthesis of molybdopterin - - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth PJD2_k127_3985519_4 391600.ABRU01000043_gene2653 2.635e-45 169.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2U73K@28211|Alphaproteobacteria,2KGU8@204458|Caulobacterales 204458|Caulobacterales H Molybdopterin - - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE PJD2_k127_3985519_6 983920.Y88_2685 5.33e-10 64.0 2AH6V@1|root,317GQ@2|Bacteria,1P9QE@1224|Proteobacteria,2UZ6C@28211|Alphaproteobacteria,2KC57@204457|Sphingomonadales 204457|Sphingomonadales S ThiS family - - - - - - - - - - - - ThiS PJD2_k127_3985519_0 1044.EH31_10945 6.652e-229 715.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,2JZVP@204457|Sphingomonadales 204457|Sphingomonadales I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_3985519_5 1030157.AFMP01000064_gene2191 1.742e-24 112.0 COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2UJ8K@28211|Alphaproteobacteria,2KDGQ@204457|Sphingomonadales 204457|Sphingomonadales M Gram-negative bacterial TonB protein C-terminal - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C PJD2_k127_3985519_2 1123267.JONN01000001_gene2393 4.617e-90 305.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K19X@204457|Sphingomonadales 204457|Sphingomonadales S L,D-transpeptidase catalytic domain - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD PJD2_k127_3995589_5 258594.RPA1708 1.432e-93 317.0 COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,2TT9T@28211|Alphaproteobacteria,3JTG7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I acyl-CoA dehydrogenase MA20_06725 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N PJD2_k127_3995589_3 1219035.NT2_01_02320 4.181e-112 371.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria,2K19R@204457|Sphingomonadales 204457|Sphingomonadales GM Dehydrogenase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind PJD2_k127_3995589_6 517722.AEUE01000002_gene2324 5.191e-52 188.0 COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,2UC8X@28211|Alphaproteobacteria,2K5WQ@204457|Sphingomonadales 204457|Sphingomonadales OU Membrane protein implicated in regulation of membrane protease activity - - - ko:K07340 - - - - ko00000 - - - NfeD PJD2_k127_3995589_2 161528.ED21_17752 7.199e-154 493.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,2K2F3@204457|Sphingomonadales 204457|Sphingomonadales O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA - - - - - - - - - - - Band_7,Band_7_C PJD2_k127_3995589_1 517722.AEUE01000004_gene893 4.576e-158 507.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2K0VS@204457|Sphingomonadales 204457|Sphingomonadales C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red PJD2_k127_3995589_4 314225.ELI_14565 7.864e-102 339.0 COG0412@1|root,COG0412@2|Bacteria,1NRB4@1224|Proteobacteria,2TU91@28211|Alphaproteobacteria,2K272@204457|Sphingomonadales 204457|Sphingomonadales Q dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH PJD2_k127_3995589_0 279238.Saro_2870 8.711e-159 506.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K18E@204457|Sphingomonadales 204457|Sphingomonadales CG Dehydrogenase - - 1.1.9.1,1.17.2.2 ko:K17760,ko:K21676 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 PJD2_k127_4018875_1 291985.CCSI01000001_gene2633 2.066e-104 342.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2K0GG@204457|Sphingomonadales 204457|Sphingomonadales EH COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N PJD2_k127_4018875_0 983920.Y88_0942 1.573e-113 383.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,2K0WU@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT PJD2_k127_4018875_2 1219035.NT2_06_03110 1.141e-80 276.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2TSEU@28211|Alphaproteobacteria,2K069@204457|Sphingomonadales 204457|Sphingomonadales E phosphoserine phosphatase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD PJD2_k127_4054958_4 237727.NAP1_08377 1.298e-15 80.0 COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,2K1AR@204457|Sphingomonadales 204457|Sphingomonadales S Methanol dehydrogenase - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase PJD2_k127_4054958_1 1122970.AUHC01000008_gene36 8.533e-87 297.0 COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,2K470@204457|Sphingomonadales 204457|Sphingomonadales S membrane - - - ko:K08988 - - - - ko00000 - - - TPM_phosphatase PJD2_k127_4054958_2 291985.CCSI01000008_gene1113 1.217e-69 249.0 COG0494@1|root,COG0494@2|Bacteria,1RE72@1224|Proteobacteria,2U805@28211|Alphaproteobacteria,2K4H0@204457|Sphingomonadales 204457|Sphingomonadales L Nudix hydrolase - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX PJD2_k127_4054958_0 685035.ADAE01000002_gene2426 6.404e-131 426.0 COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2TT6C@28211|Alphaproteobacteria,2K269@204457|Sphingomonadales 204457|Sphingomonadales IQ KR domain - - - - - - - - - - - - adh_short_C2 PJD2_k127_4054958_3 314225.ELI_08970 1.261e-19 89.0 COG1983@1|root,COG1983@2|Bacteria,1NGIB@1224|Proteobacteria,2UJTZ@28211|Alphaproteobacteria,2K7V9@204457|Sphingomonadales 204457|Sphingomonadales KT PspC domain - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC PJD2_k127_4143322_0 161528.ED21_19687 6.537e-178 561.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,2K0TK@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 PJD2_k127_4143322_3 314225.ELI_13250 2.163e-65 227.0 COG1495@1|root,COG1495@2|Bacteria,1N89I@1224|Proteobacteria,2UF49@28211|Alphaproteobacteria,2K59V@204457|Sphingomonadales 204457|Sphingomonadales O Disulfide bond formation protein - - - - - - - - - - - - DsbB PJD2_k127_4143322_2 161528.ED21_19697 1.796e-74 263.0 COG2941@1|root,COG2941@2|Bacteria,1RAK4@1224|Proteobacteria,2U85I@28211|Alphaproteobacteria,2K46W@204457|Sphingomonadales 204457|Sphingomonadales H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 PJD2_k127_4143322_4 685035.ADAE01000023_gene1577 2.661e-55 199.0 2BJB4@1|root,32DM3@2|Bacteria,1N0RM@1224|Proteobacteria,2UDXW@28211|Alphaproteobacteria,2KDJM@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_4143322_1 291985.CCSI01000003_gene124 8.703e-86 286.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2K1AN@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N PJD2_k127_4363584_3 314225.ELI_00250 7.345e-174 561.0 COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,2U3NB@28211|Alphaproteobacteria,2K0X3@204457|Sphingomonadales 204457|Sphingomonadales S Membrane protein involved in the export of O-antigen and teichoic acid - - - - - - - - - - - - Polysacc_synt_3,Polysacc_synt_C PJD2_k127_4363584_4 314225.ELI_00245 4.491e-105 349.0 COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U8U8@28211|Alphaproteobacteria,2KCU8@204457|Sphingomonadales 204457|Sphingomonadales S gag-polyprotein putative aspartyl protease - - - - - - - - - - - - Asp_protease_2 PJD2_k127_4363584_1 314225.ELI_00240 1.795e-283 881.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,2K16I@204457|Sphingomonadales 204457|Sphingomonadales V ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran PJD2_k127_4363584_8 1282360.ABAC460_22025 2.333e-36 148.0 COG2010@1|root,COG2010@2|Bacteria,1NEUK@1224|Proteobacteria,2UIJ4@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 PJD2_k127_4363584_0 685035.ADAE01000011_gene1259 0.0 1142.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2K2A4@204457|Sphingomonadales 204457|Sphingomonadales S Peptidase, M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_4363584_2 1219035.NT2_04_04860 9.283e-236 736.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,2K0UP@204457|Sphingomonadales 204457|Sphingomonadales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small PJD2_k127_4363584_5 685035.ADAE01000011_gene1254 9.664e-101 330.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,2K0IZ@204457|Sphingomonadales 204457|Sphingomonadales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome PJD2_k127_4363584_6 291985.CCSI01000006_gene1264 1.971e-57 211.0 COG2913@1|root,COG2913@2|Bacteria,1RHYM@1224|Proteobacteria,2UBU9@28211|Alphaproteobacteria,2K4H5@204457|Sphingomonadales 204457|Sphingomonadales J Small protein A (tmRNA-binding) - - - - - - - - - - - - SmpA_OmlA PJD2_k127_4363584_7 1219035.NT2_04_04830 7.217e-48 177.0 COG5452@1|root,COG5452@2|Bacteria,1N12T@1224|Proteobacteria,2UCES@28211|Alphaproteobacteria,2K5B4@204457|Sphingomonadales 204457|Sphingomonadales S Ubiquinol-cytochrome C chaperone - - - ko:K17662 - - - - ko00000,ko03029 - - - Ubiq_cyt_C_chap PJD2_k127_4363584_10 517722.AEUE01000008_gene112 1.234e-14 83.0 COG1399@1|root,COG1399@2|Bacteria,1N7C2@1224|Proteobacteria,2UC4J@28211|Alphaproteobacteria,2K4K6@204457|Sphingomonadales 204457|Sphingomonadales S Uncharacterized ACR, COG1399 - - - - - - - - - - - - DUF177 PJD2_k127_4430866_3 1121106.JQKB01000070_gene839 3.467e-28 115.0 COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TRM9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S 2-nitropropane dioxygenase MA20_16415 - - - - - - - - - - - NMO PJD2_k127_4430866_1 279238.Saro_0562 4.645e-102 336.0 2A6PY@1|root,30VHV@2|Bacteria,1R9ZB@1224|Proteobacteria,2U5YW@28211|Alphaproteobacteria,2K386@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_4430866_0 627192.SLG_16370 3.342e-120 399.0 COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,2U5M0@28211|Alphaproteobacteria,2KEAE@204457|Sphingomonadales 204457|Sphingomonadales EGP of the major facilitator superfamily - - - - - - - - - - - - MFS_1 PJD2_k127_4430866_2 1096930.L284_04690 4.35e-46 167.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria,2K02E@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N PJD2_k127_4498477_0 158500.BV97_01554 2.897e-217 681.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,2K008@204457|Sphingomonadales 204457|Sphingomonadales U Flp pilus assembly protein, ATPase CpaF - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE PJD2_k127_4498477_1 1122612.AUBA01000018_gene2661 3.54e-59 225.0 28N8A@1|root,2ZBCR@2|Bacteria,1R7YF@1224|Proteobacteria,2U4D7@28211|Alphaproteobacteria,2K9QK@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_4498477_2 1120705.FG95_00656 5.353e-47 171.0 2A25G@1|root,30QFW@2|Bacteria,1NY82@1224|Proteobacteria,2UT59@28211|Alphaproteobacteria,2K55F@204457|Sphingomonadales 204457|Sphingomonadales S Ribbon-helix-helix protein, copG family - - - - - - - - - - - - RHH_1 PJD2_k127_4498477_3 1522072.IL54_3199 0.0001812 44.0 COG1487@1|root,COG1487@2|Bacteria,1MZCD@1224|Proteobacteria,2US0Y@28211|Alphaproteobacteria,2KCG2@204457|Sphingomonadales 204457|Sphingomonadales S PIN domain - - - - - - - - - - - - PIN PJD2_k127_4528047_7 291985.CCSI01000002_gene1593 1.536e-15 76.0 2C7BT@1|root,33MZ9@2|Bacteria,1NMQ4@1224|Proteobacteria,2UG5B@28211|Alphaproteobacteria,2K40I@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - Porin_4 PJD2_k127_4528047_4 317655.Sala_2255 2.542e-135 436.0 COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria,2K0A2@204457|Sphingomonadales 204457|Sphingomonadales IQ Acetoacetyl-CoA reductase phbB - 1.1.1.36 ko:K00023 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R01779,R01977 RC00103,RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 PJD2_k127_4528047_2 1096930.L284_06845 3.755e-175 559.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K0PR@204457|Sphingomonadales 204457|Sphingomonadales M synthase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS PJD2_k127_4528047_6 279238.Saro_3211 6.569e-34 131.0 COG4321@1|root,COG4321@2|Bacteria,1PSCA@1224|Proteobacteria,2VA8Q@28211|Alphaproteobacteria,2K6W1@204457|Sphingomonadales 204457|Sphingomonadales S protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis - - - - - - - - - - - - RHH_4 PJD2_k127_4528047_8 279238.Saro_3330 1.438e-14 79.0 2BPD1@1|root,32I52@2|Bacteria,1Q8DX@1224|Proteobacteria,2VEKH@28211|Alphaproteobacteria,2K82G@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_4528047_0 314225.ELI_12305 1.396e-231 721.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,2K1H1@204457|Sphingomonadales 204457|Sphingomonadales M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase PJD2_k127_4528047_3 1174684.EBMC1_04374 1.077e-151 484.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2TRT6@28211|Alphaproteobacteria,2K1NI@204457|Sphingomonadales 204457|Sphingomonadales M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase PJD2_k127_4528047_1 1112214.AHIS01000049_gene2346 4.143e-210 668.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,2K1E7@204457|Sphingomonadales 204457|Sphingomonadales P Citrate transporter - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C PJD2_k127_4528047_5 314225.ELI_12320 2.412e-81 271.0 COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TU15@28211|Alphaproteobacteria,2K1GE@204457|Sphingomonadales 204457|Sphingomonadales Q cytochrome P450 - - - - - - - - - - - - p450 PJD2_k127_4554168_2 685035.ADAE01000005_gene2009 2.014e-127 415.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria,2K12J@204457|Sphingomonadales 204457|Sphingomonadales I synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding PJD2_k127_4554168_0 279238.Saro_0192 1.125e-210 675.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2K0PZ@204457|Sphingomonadales 204457|Sphingomonadales E gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept PJD2_k127_4554168_1 291985.CCSI01000002_gene1475 1.782e-135 440.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2TRF8@28211|Alphaproteobacteria,2K1QF@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh PJD2_k127_4554168_5 1090318.ATTI01000001_gene943 3.768e-45 179.0 COG5592@1|root,COG5592@2|Bacteria,1N6KG@1224|Proteobacteria,2UCBE@28211|Alphaproteobacteria,2K1MZ@204457|Sphingomonadales 204457|Sphingomonadales S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin PJD2_k127_4554168_4 161528.ED21_19237 7.309e-59 206.0 COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2UAVK@28211|Alphaproteobacteria,2K421@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - - - - - - - - - - Rrf2 PJD2_k127_4554168_3 1248917.ANFX01000013_gene1495 1.487e-69 243.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,2TRU6@28211|Alphaproteobacteria,2K196@204457|Sphingomonadales 204457|Sphingomonadales O ABC-type transport system involved in Fe-S cluster assembly, permease component sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 PJD2_k127_4555091_1 517722.AEUE01000001_gene2752 1.357e-63 221.0 COG3713@1|root,COG3713@2|Bacteria,1RF1U@1224|Proteobacteria,2U8SJ@28211|Alphaproteobacteria,2K4FB@204457|Sphingomonadales 204457|Sphingomonadales M MltA-interacting protein MipA - - - - - - - - - - - - MipA PJD2_k127_4555091_0 1044.EH31_05865 4.928e-178 561.0 COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,2TV2E@28211|Alphaproteobacteria,2K3J0@204457|Sphingomonadales 204457|Sphingomonadales P Flavin-binding monooxygenase-like - - - - - - - - - - - - FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 PJD2_k127_4558197_1 1122970.AUHC01000004_gene2212 5.596e-132 431.0 2DB8I@1|root,2Z7RY@2|Bacteria,1MY4M@1224|Proteobacteria,2U2A8@28211|Alphaproteobacteria,2K1YC@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_4558197_0 279238.Saro_2220 1.119e-140 455.0 COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,2K39Q@204457|Sphingomonadales 204457|Sphingomonadales S Ecdysteroid kinase - - - - - - - - - - - - APH,EcKinase PJD2_k127_4558197_3 685035.ADAE01000018_gene634 1.716e-41 155.0 2DSF2@1|root,33FWB@2|Bacteria,1NGGP@1224|Proteobacteria,2UMB6@28211|Alphaproteobacteria,2K40K@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - PRC PJD2_k127_4558197_2 685035.ADAE01000018_gene633 5.447e-54 190.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K02W@204457|Sphingomonadales 28211|Alphaproteobacteria O peptidase M13 - - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N PJD2_k127_4591439_5 317655.Sala_0180 3.872e-64 227.0 COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,2U1ZY@28211|Alphaproteobacteria,2K04U@204457|Sphingomonadales 204457|Sphingomonadales PT Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 PJD2_k127_4591439_2 1088721.NSU_1740 6.113e-160 508.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2TR10@28211|Alphaproteobacteria,2K1AU@204457|Sphingomonadales 204457|Sphingomonadales C Electron transfer flavoprotein etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha PJD2_k127_4591439_3 1219035.NT2_04_04080 1.763e-136 437.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,2K0GH@204457|Sphingomonadales 204457|Sphingomonadales C Electron transfer flavoprotein - - - ko:K03521 - - - - ko00000 - - - ETF PJD2_k127_4591439_1 383381.EH30_15410 5.215e-223 695.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,2K12N@204457|Sphingomonadales 204457|Sphingomonadales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA PJD2_k127_4591439_4 1248917.ANFX01000026_gene1040 3.876e-120 391.0 COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria,2K171@204457|Sphingomonadales 204457|Sphingomonadales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P PJD2_k127_4591439_0 1550073.JROH01000005_gene1513 4.661e-299 919.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2U29S@28211|Alphaproteobacteria,2K0TJ@204457|Sphingomonadales 204457|Sphingomonadales S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 PJD2_k127_4641858_13 1248917.ANFX01000005_gene148 8.925e-32 124.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,2K54P@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the HesB IscA family erpA - - - - - - - - - - - Fe-S_biosyn PJD2_k127_4641858_2 1096930.L284_15350 2.097e-139 448.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,2K0HF@204457|Sphingomonadales 204457|Sphingomonadales L exodeoxyribonuclease III xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos PJD2_k127_4641858_10 314225.ELI_12955 3.108e-68 239.0 COG3773@1|root,COG3773@2|Bacteria,1RDSV@1224|Proteobacteria,2U8XY@28211|Alphaproteobacteria,2K4PG@204457|Sphingomonadales 204457|Sphingomonadales M COG3773 Cell wall hydrolyses involved in spore germination - - - - - - - - - - - - Hydrolase_2 PJD2_k127_4641858_12 383381.EH30_14980 4.418e-34 133.0 COG5447@1|root,COG5447@2|Bacteria,1N1KU@1224|Proteobacteria,2UFES@28211|Alphaproteobacteria,2K70S@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1491) - - - - - - - - - - - - DUF1491 PJD2_k127_4641858_8 383381.EH30_14985 8.2e-75 253.0 COG2050@1|root,COG2050@2|Bacteria,1RG2U@1224|Proteobacteria,2U7W4@28211|Alphaproteobacteria,2KD7K@204457|Sphingomonadales 204457|Sphingomonadales Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT PJD2_k127_4641858_14 1122137.AQXF01000001_gene3176 6.148e-25 112.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria 28211|Alphaproteobacteria G PTS IIA-like nitrogen-regulatory protein PtsN ptsN2 - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 PJD2_k127_4641858_6 314225.ELI_12975 4.639e-89 297.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria,2K2CA@204457|Sphingomonadales 204457|Sphingomonadales J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf - - - - - - - - - - - Ribosom_S30AE_C,Ribosomal_S30AE PJD2_k127_4641858_5 291985.CCSI01000002_gene1441 9.743e-105 344.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,2K06H@204457|Sphingomonadales 204457|Sphingomonadales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T PJD2_k127_4641858_7 1219035.NT2_04_03410 8.383e-84 285.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,2K3YB@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE - 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE PJD2_k127_4641858_3 1122970.AUHC01000010_gene1630 1.956e-123 407.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,2K1U1@204457|Sphingomonadales 204457|Sphingomonadales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N PJD2_k127_4641858_9 158500.BV97_02104 1.044e-68 240.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2U9H5@28211|Alphaproteobacteria,2K2S3@204457|Sphingomonadales 204457|Sphingomonadales D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf PJD2_k127_4641858_1 237727.NAP1_13028 7.407e-141 456.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2TT66@28211|Alphaproteobacteria,2K0GA@204457|Sphingomonadales 204457|Sphingomonadales S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation - - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase PJD2_k127_4641858_0 279238.Saro_0118 2.1e-166 528.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria,2JZZP@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D PJD2_k127_4641858_11 1096930.L284_15290 5.275e-63 220.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2U987@28211|Alphaproteobacteria,2K4J9@204457|Sphingomonadales 204457|Sphingomonadales S membrane - - - ko:K08973 - - - - ko00000 - - - UPF0093 PJD2_k127_4641858_4 161528.ED21_19452 3.109e-109 355.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,2K1UD@204457|Sphingomonadales 204457|Sphingomonadales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind PJD2_k127_4675798_1 237727.NAP1_04380 2.004e-173 547.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,2K0PF@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt PJD2_k127_4675798_2 1030157.AFMP01000031_gene3014 4.279e-160 515.0 COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,2TRNM@28211|Alphaproteobacteria,2K3P4@204457|Sphingomonadales 204457|Sphingomonadales P Natural resistance-associated macrophage protein - - - - - - - - - - - - Nramp PJD2_k127_4675798_5 1144305.PMI02_01596 1.088e-46 179.0 COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2USI1@28211|Alphaproteobacteria,2K2ZM@204457|Sphingomonadales 204457|Sphingomonadales M Gram-negative bacterial TonB protein C-terminal - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C PJD2_k127_4675798_0 291985.CCSI01000005_gene994 0.0 1081.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,2K0MC@204457|Sphingomonadales 204457|Sphingomonadales L ATP-dependent DNA helicase RecG recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge PJD2_k127_4675798_4 1207055.C100_15585 1.313e-58 209.0 COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,2U7JS@28211|Alphaproteobacteria,2K402@204457|Sphingomonadales 204457|Sphingomonadales S Hemerythrin - - - - - - - - - - - - Hemerythrin PJD2_k127_4675798_6 1248917.ANFX01000024_gene1178 2.527e-38 145.0 COG2938@1|root,COG2938@2|Bacteria,1N6SJ@1224|Proteobacteria,2VCGJ@28211|Alphaproteobacteria,2K5W5@204457|Sphingomonadales 204457|Sphingomonadales S Flavinator of succinate dehydrogenase - - - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 PJD2_k127_4675798_3 1219035.NT2_01_01020 5.307e-108 355.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2K07V@204457|Sphingomonadales 204457|Sphingomonadales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF PJD2_k127_4898191_2 291985.CCSI01000002_gene1761 7.3e-53 193.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,2K0DH@204457|Sphingomonadales 204457|Sphingomonadales H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 PJD2_k127_4898191_0 291985.CCSI01000002_gene1762 4.468e-240 746.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,2K044@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 PJD2_k127_4898191_1 685035.ADAE01000002_gene2117 3.777e-135 450.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2TVIF@28211|Alphaproteobacteria,2K0X5@204457|Sphingomonadales 204457|Sphingomonadales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp PJD2_k127_4900600_3 517722.AEUE01000004_gene995 1.347e-54 199.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,2JZXN@204457|Sphingomonadales 204457|Sphingomonadales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG PJD2_k127_4900600_0 1123267.JONN01000001_gene665 1.259e-234 730.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TR32@28211|Alphaproteobacteria,2JZXI@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt PJD2_k127_4900600_5 685035.ADAE01000020_gene1541 2.824e-39 149.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UBWW@28211|Alphaproteobacteria,2K5X6@204457|Sphingomonadales 204457|Sphingomonadales IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding PJD2_k127_4900600_2 1122970.AUHC01000005_gene1967 2.939e-103 342.0 COG3904@1|root,COG3904@2|Bacteria,1R6HZ@1224|Proteobacteria,2U0MS@28211|Alphaproteobacteria,2K184@204457|Sphingomonadales 204457|Sphingomonadales S periplasmic protein - - - - - - - - - - - - - PJD2_k127_4900600_4 279238.Saro_1328 4.063e-47 176.0 2C3YK@1|root,2ZHJ2@2|Bacteria,1RKGM@1224|Proteobacteria,2UBK5@28211|Alphaproteobacteria,2K5GJ@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_4900600_1 314225.ELI_03965 3.302e-196 614.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2TR9U@28211|Alphaproteobacteria,2K0PT@204457|Sphingomonadales 204457|Sphingomonadales J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon PJD2_k127_4913686_0 1219035.NT2_02_05070 1.342e-241 751.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,2K08Q@204457|Sphingomonadales 204457|Sphingomonadales E 5-aminolevulinic acid synthase - - 2.3.1.37 ko:K00643 ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110 - R00830 RC00004,RC02815 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 PJD2_k127_4913686_1 1248917.ANFX01000023_gene1242 1.809e-71 256.0 COG4585@1|root,COG4585@2|Bacteria,1RKV1@1224|Proteobacteria,2U32D@28211|Alphaproteobacteria,2KDGC@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 PJD2_k127_4961994_0 1219035.NT2_01_02970 1.165e-188 599.0 COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2TW1S@28211|Alphaproteobacteria,2K09D@204457|Sphingomonadales 204457|Sphingomonadales EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 PJD2_k127_4961994_1 383381.EH30_03710 4.462e-103 338.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,2K47C@204457|Sphingomonadales 204457|Sphingomonadales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf PJD2_k127_4961994_2 1096930.L284_12755 3.489e-29 118.0 2ER9Q@1|root,33IVB@2|Bacteria,1NJ3C@1224|Proteobacteria,2UK03@28211|Alphaproteobacteria,2K77T@204457|Sphingomonadales 204457|Sphingomonadales S UvrB/uvrC motif - - - - - - - - - - - - UVR PJD2_k127_4961994_5 1088721.NSU_3657 1.355e-06 54.0 2AN5X@1|root,31D3U@2|Bacteria,1P3YU@1224|Proteobacteria,2UW6S@28211|Alphaproteobacteria,2KC3Q@204457|Sphingomonadales 204457|Sphingomonadales S PilZ domain - - - - - - - - - - - - PilZ PJD2_k127_4962492_3 1479239.JQMU01000001_gene1132 1.595e-23 100.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,2K0E4@204457|Sphingomonadales 204457|Sphingomonadales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim PJD2_k127_4962492_2 1479239.JQMU01000001_gene1132 7.514e-213 667.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,2K0E4@204457|Sphingomonadales 204457|Sphingomonadales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim PJD2_k127_4962492_1 1123270.ATUR01000002_gene2592 2.874e-236 738.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,2TUHT@28211|Alphaproteobacteria,2K1MW@204457|Sphingomonadales 204457|Sphingomonadales E Acetylornithine deacetylase Succinyl-diaminopimelate - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 PJD2_k127_4962492_0 314225.ELI_11720 1.577e-250 793.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2U0WI@28211|Alphaproteobacteria,2K09R@204457|Sphingomonadales 204457|Sphingomonadales IQ AMP-binding enzyme C-terminal domain - - - - - - - - - - - - AMP-binding,AMP-binding_C PJD2_k127_5089856_4 291985.CCSI01000001_gene2294 1.36e-51 186.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,2K2F1@204457|Sphingomonadales 204457|Sphingomonadales O OsmC-like protein - - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC PJD2_k127_5089856_2 161528.ED21_27378 1.339e-118 391.0 COG0745@1|root,COG3920@1|root,COG0745@2|Bacteria,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,2TSSQ@28211|Alphaproteobacteria,2K1WB@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase-like ATPase domain - - - - - - - - - - - - HATPase_c,HATPase_c_2,HisKA_2,Response_reg PJD2_k127_5089856_3 161528.ED21_27383 8.997e-74 250.0 COG2197@1|root,COG2197@2|Bacteria,1QWB3@1224|Proteobacteria,2TWYK@28211|Alphaproteobacteria,2K428@204457|Sphingomonadales 204457|Sphingomonadales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg PJD2_k127_5089856_1 291985.CCSI01000001_gene2297 1.509e-149 488.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TSPY@28211|Alphaproteobacteria,2K297@204457|Sphingomonadales 204457|Sphingomonadales T CHASE3 domain - - - - - - - - - - - - CHASE3,HATPase_c,HisKA PJD2_k127_5089856_0 1248917.ANFX01000008_gene273 8.576e-195 610.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,2K2GE@204457|Sphingomonadales 204457|Sphingomonadales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim PJD2_k127_5092095_4 314225.ELI_11335 4.274e-33 129.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,2K1HR@204457|Sphingomonadales 204457|Sphingomonadales O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 PJD2_k127_5092095_1 279238.Saro_3331 9.917e-225 708.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2K08H@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 PJD2_k127_5092095_0 314225.ELI_11345 0.0 1034.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,2K0HX@204457|Sphingomonadales 204457|Sphingomonadales M penicillin-binding protein - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase PJD2_k127_5092095_2 314225.ELI_11350 1.893e-66 229.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U5Q0@28211|Alphaproteobacteria,2K40G@204457|Sphingomonadales 204457|Sphingomonadales O COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR PJD2_k127_5092095_3 1479239.JQMU01000001_gene1054 5.068e-54 190.0 COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria,2K1DG@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 PJD2_k127_5126038_0 314225.ELI_05895 2.007e-207 649.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,2K0RG@204457|Sphingomonadales 204457|Sphingomonadales I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N PJD2_k127_5126038_4 1122970.AUHC01000001_gene459 5.471e-63 219.0 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,2U98M@28211|Alphaproteobacteria,2K58T@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 PJD2_k127_5126038_5 1096930.L284_03120 3.911e-46 169.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2UCKH@28211|Alphaproteobacteria,2K56R@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19 ko:K01496 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04037 RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH PJD2_k127_5126038_2 555793.WSK_3882 1.369e-97 326.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,2K09E@204457|Sphingomonadales 204457|Sphingomonadales S Competence protein - - - - - - - - - - - - Pribosyltran PJD2_k127_5126038_3 702113.PP1Y_AT25302 5.575e-65 235.0 COG0500@1|root,COG0500@2|Bacteria,1QUNM@1224|Proteobacteria,2TW20@28211|Alphaproteobacteria,2KE91@204457|Sphingomonadales 204457|Sphingomonadales Q Methyltransferase - - - - - - - - - - - - Methyltransf_23 PJD2_k127_5126038_1 279238.Saro_2110 5.341e-119 384.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,2K0KY@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N PJD2_k127_5167491_3 291985.CCSI01000004_gene746 8.068e-83 279.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria,2K1SR@204457|Sphingomonadales 204457|Sphingomonadales J Polynucleotide adenylyltransferase cca - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd PJD2_k127_5167491_6 279238.Saro_1022 4.429e-69 240.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,2K3ZW@204457|Sphingomonadales 204457|Sphingomonadales L Nudix hydrolase - - - - - - - - - - - - NUDIX PJD2_k127_5167491_4 314225.ELI_02255 7.706e-77 264.0 COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,2U7DA@28211|Alphaproteobacteria,2K0YC@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09986 - - - - ko00000 - - - DUF1285 PJD2_k127_5167491_7 983920.Y88_3288 9.731e-65 229.0 COG3153@1|root,COG3153@2|Bacteria,1RD0C@1224|Proteobacteria,2U7AS@28211|Alphaproteobacteria,2K560@204457|Sphingomonadales 204457|Sphingomonadales S Acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_9 PJD2_k127_5167491_0 314225.ELI_02265 9.288e-169 538.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales 204457|Sphingomonadales G glucose sorbosone - - - - - - - - - - - - GSDH PJD2_k127_5167491_2 627192.SLG_22620 4.341e-83 285.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,2K1EB@204457|Sphingomonadales 204457|Sphingomonadales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII PJD2_k127_5167491_5 1088721.NSU_4113 9.17e-70 243.0 KOG2391@1|root,3279X@2|Bacteria,1RHDJ@1224|Proteobacteria,2U9SJ@28211|Alphaproteobacteria,2KBN3@204457|Sphingomonadales 204457|Sphingomonadales O Sulfotransferase family - - - - - - - - - - - - - PJD2_k127_5167491_1 314225.ELI_02295 2.319e-134 430.0 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,2K0RE@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K13581 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko02048 - - - N6_N4_Mtase PJD2_k127_5173846_2 1057002.KB905370_gene4455 5.952e-189 605.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,4BBS0@82115|Rhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N PJD2_k127_5173846_4 1123267.JONN01000001_gene977 2.647e-79 272.0 COG1738@1|root,COG1738@2|Bacteria,1RJV6@1224|Proteobacteria,2U7IX@28211|Alphaproteobacteria,2K2CH@204457|Sphingomonadales 204457|Sphingomonadales S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 PJD2_k127_5173846_1 685035.ADAE01000002_gene2355 1.35e-203 645.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria,2K07T@204457|Sphingomonadales 204457|Sphingomonadales F nucleoside - - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N PJD2_k127_5173846_3 291985.CCSI01000003_gene341 2.42e-169 535.0 COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,2TU3Y@28211|Alphaproteobacteria,2K1Y3@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N PJD2_k127_5173846_0 314225.ELI_11175 0.0 1150.0 COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,2TSK9@28211|Alphaproteobacteria,2KCG3@204457|Sphingomonadales 204457|Sphingomonadales P membrane - - - - - - - - - - - - CarboxypepD_reg PJD2_k127_5173846_5 1122970.AUHC01000002_gene1403 5.761e-48 180.0 COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2UJ8K@28211|Alphaproteobacteria,2K536@204457|Sphingomonadales 204457|Sphingomonadales M Gram-negative bacterial TonB protein C-terminal - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C PJD2_k127_5181884_1 1044.EH31_09555 1.787e-150 492.0 COG3449@1|root,COG3449@2|Bacteria,1QU1G@1224|Proteobacteria,2TW36@28211|Alphaproteobacteria,2K0CS@204457|Sphingomonadales 204457|Sphingomonadales L Domain of unknown function (DUF4153) - - - - - - - - - - - - DUF4153 PJD2_k127_5181884_4 1122970.AUHC01000004_gene2225 9.939e-64 226.0 COG0545@1|root,COG0545@2|Bacteria,1RKD4@1224|Proteobacteria,2UANS@28211|Alphaproteobacteria,2KDTM@204457|Sphingomonadales 204457|Sphingomonadales O Peptidyl-prolyl cis-trans - - - - - - - - - - - - FKBP_C PJD2_k127_5181884_6 1122612.AUBA01000022_gene3094 5.714e-29 120.0 COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,2UC58@28211|Alphaproteobacteria,2K5X3@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the bacterial ribosomal protein bS21 family rpsU - - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 PJD2_k127_5181884_5 1219035.NT2_05_03360 2.745e-45 168.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,2K5ZR@204457|Sphingomonadales 204457|Sphingomonadales D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB PJD2_k127_5181884_0 1219035.NT2_05_03350 2.464e-178 569.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria,2K1YR@204457|Sphingomonadales 204457|Sphingomonadales J Responsible for synthesis of pseudouridine from uracil - - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 PJD2_k127_5181884_2 279238.Saro_2838 2.62e-87 311.0 COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,2U5JV@28211|Alphaproteobacteria,2K2BS@204457|Sphingomonadales 204457|Sphingomonadales K Putative FMN-binding domain - - - ko:K07734 - - - - ko00000,ko03000 - - - FMN_bind_2 PJD2_k127_5181884_3 383381.EH30_01415 3.398e-78 267.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2U703@28211|Alphaproteobacteria,2K3XQ@204457|Sphingomonadales 204457|Sphingomonadales S Hydrolase - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 PJD2_k127_5191896_0 291985.CCSI01000002_gene1341 0.0 1202.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,2K072@204457|Sphingomonadales 204457|Sphingomonadales E aminopeptidase N pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 PJD2_k127_5191896_1 1088721.NSU_1829 4.584e-170 543.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2TVI9@28211|Alphaproteobacteria,2K2GU@204457|Sphingomonadales 204457|Sphingomonadales O CAAX prenyl protease N-terminal, five membrane helices - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N PJD2_k127_5191896_5 685035.ADAE01000023_gene1665 1.893e-107 361.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2TRDY@28211|Alphaproteobacteria,2K1E4@204457|Sphingomonadales 204457|Sphingomonadales GM epimerase - - - - - - - - - - - - - PJD2_k127_5191896_4 1096930.L284_21655 2.326e-116 386.0 COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,2TVBG@28211|Alphaproteobacteria,2K0J7@204457|Sphingomonadales 204457|Sphingomonadales EG Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA PJD2_k127_5191896_2 685035.ADAE01000023_gene1663 1.405e-156 499.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria,2K0EJ@204457|Sphingomonadales 204457|Sphingomonadales E Threonine aldolase ltaA - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase PJD2_k127_5191896_7 279238.Saro_3266 2.336e-32 142.0 COG2388@1|root,COG2388@2|Bacteria,1N6YS@1224|Proteobacteria,2UG30@28211|Alphaproteobacteria,2K764@204457|Sphingomonadales 204457|Sphingomonadales S GCN5-related N-acetyl-transferase - - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG PJD2_k127_5191896_8 981384.AEYW01000007_gene1330 7.952e-06 49.0 COG1961@1|root,COG1961@2|Bacteria,1Q90G@1224|Proteobacteria,2V7E8@28211|Alphaproteobacteria,4NDK6@97050|Ruegeria 28211|Alphaproteobacteria L Recombinase zinc beta ribbon domain - - - - - - - - - - - - Resolvase,Zn_ribbon_recom PJD2_k127_5191896_3 383381.EH30_15470 8.483e-125 402.0 COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2TSQ0@28211|Alphaproteobacteria,2K06W@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily gpmA - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 PJD2_k127_5191896_6 685035.ADAE01000023_gene1658 3.547e-44 163.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,2K3Z8@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC PJD2_k127_5210634_1 1044.EH31_05925 3.366e-125 405.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2K27B@204457|Sphingomonadales 204457|Sphingomonadales I acetyl propionyl-CoA carboxylase, alpha subunit - - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 PJD2_k127_5210634_4 509190.Cseg_0119 8.952e-21 98.0 2CM2H@1|root,32SDI@2|Bacteria,1NPEY@1224|Proteobacteria,2UJZ9@28211|Alphaproteobacteria,2KJCV@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - PJD2_k127_5210634_0 314225.ELI_09895 2.114e-140 464.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2TTI0@28211|Alphaproteobacteria,2K2BH@204457|Sphingomonadales 204457|Sphingomonadales I Phytoene synthase crtB - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY PJD2_k127_5210634_2 291985.CCSI01000003_gene247 3.824e-106 348.0 COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,2K0TW@204457|Sphingomonadales 204457|Sphingomonadales K Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox PJD2_k127_5210634_3 685035.ADAE01000008_gene3052 2.036e-22 96.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2K17H@204457|Sphingomonadales 204457|Sphingomonadales Q Phytoene dehydrogenase crtI - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase PJD2_k127_524263_4 383381.EH30_14325 1.077e-59 214.0 2AKT1@1|root,31BK2@2|Bacteria,1NXBB@1224|Proteobacteria,2UTRK@28211|Alphaproteobacteria,2K5KP@204457|Sphingomonadales 204457|Sphingomonadales S PilZ domain - - - - - - - - - - - - PilZ PJD2_k127_524263_0 383381.EH30_09955 1.037e-312 962.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,2K1TD@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 PJD2_k127_524263_3 1219035.NT2_06_02690 5.42e-135 433.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2TRGW@28211|Alphaproteobacteria,2K220@204457|Sphingomonadales 204457|Sphingomonadales C Peptidase S41 - - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO PJD2_k127_524263_5 279238.Saro_2576 2.199e-14 79.0 COG4736@1|root,COG4736@2|Bacteria 2|Bacteria O Cbb3-type cytochrome oxidase ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ PJD2_k127_524263_2 1331060.RLDS_18020 2.061e-137 442.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,2K23A@204457|Sphingomonadales 204457|Sphingomonadales C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrom_C,Cytochrome_CBB3,FixP_N PJD2_k127_524263_1 517722.AEUE01000002_gene2367 3.615e-187 589.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2TRYB@28211|Alphaproteobacteria,2K0BY@204457|Sphingomonadales 204457|Sphingomonadales C Nitrogen fixation protein fixG ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C PJD2_k127_5266124_0 685035.ADAE01000018_gene1158 3.389e-132 425.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,2K04H@204457|Sphingomonadales 204457|Sphingomonadales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey PJD2_k127_5266124_4 1219035.NT2_02_05080 1.832e-65 235.0 COG2199@1|root,COG3706@2|Bacteria,1NVZM@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF,PAS_4 PJD2_k127_5266124_5 1096930.L284_14645 3.461e-48 180.0 COG1396@1|root,COG1396@2|Bacteria,1NN2X@1224|Proteobacteria,2UC4B@28211|Alphaproteobacteria,2KDPF@204457|Sphingomonadales 204457|Sphingomonadales K Helix-turn-helix domain - - - - - - - - - - - - HTH_31,PilZ PJD2_k127_5266124_3 279238.Saro_1064 3.22e-110 364.0 COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,2K289@204457|Sphingomonadales 204457|Sphingomonadales I Acyl-CoA thioesterase - - - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT_3 PJD2_k127_5266124_1 517722.AEUE01000007_gene377 7.118e-129 417.0 COG2850@1|root,COG2850@2|Bacteria,1MXD0@1224|Proteobacteria,2U0CY@28211|Alphaproteobacteria,2K1HD@204457|Sphingomonadales 204457|Sphingomonadales S A domain family that is part of the cupin metalloenzyme superfamily. - - - - - - - - - - - - Cupin_8 PJD2_k127_5266124_2 1096930.L284_16495 2.553e-125 413.0 COG5653@1|root,COG5653@2|Bacteria,1N3Z9@1224|Proteobacteria,2TRT5@28211|Alphaproteobacteria,2K1RW@204457|Sphingomonadales 204457|Sphingomonadales M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 PJD2_k127_5266124_6 1112212.JH584235_gene3230 2.56e-34 131.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2TR9G@28211|Alphaproteobacteria,2K0XA@204457|Sphingomonadales 204457|Sphingomonadales C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase PJD2_k127_528416_0 517722.AEUE01000007_gene370 8.812e-302 955.0 COG4206@1|root,COG4206@2|Bacteria,1MXFM@1224|Proteobacteria,2TWYV@28211|Alphaproteobacteria,2K14T@204457|Sphingomonadales 204457|Sphingomonadales H Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_528416_4 685035.ADAE01000018_gene953 1.76e-40 168.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,2K5VJ@204457|Sphingomonadales 204457|Sphingomonadales J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a PJD2_k127_528416_3 1219035.NT2_02_02670 2.057e-88 296.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,2K3WJ@204457|Sphingomonadales 204457|Sphingomonadales D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf PJD2_k127_528416_2 1219035.NT2_02_02680 3.986e-96 333.0 COG1530@1|root,COG1530@2|Bacteria,1RC15@1224|Proteobacteria,2U5PB@28211|Alphaproteobacteria,2K2AZ@204457|Sphingomonadales 204457|Sphingomonadales J ribonuclease E activity - - - - - - - - - - - - RNase_E_G PJD2_k127_528416_5 1479239.JQMU01000001_gene2442 2.121e-19 90.0 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VEGK@28211|Alphaproteobacteria,2K7UE@204457|Sphingomonadales 204457|Sphingomonadales S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG - - ko:K09862 - - - - ko00000 - - - YacG PJD2_k127_528416_6 1197906.CAJQ02000003_gene3219 1.793e-08 58.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JUGV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Resolvase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom PJD2_k127_528416_1 13689.BV96_01122 2.014e-113 372.0 COG0582@1|root,COG0582@2|Bacteria,1R4UZ@1224|Proteobacteria,2U0XX@28211|Alphaproteobacteria,2K3QA@204457|Sphingomonadales 204457|Sphingomonadales L Phage integrase family - - - - - - - - - - - - Phage_integrase PJD2_k127_5300518_6 317655.Sala_2241 2.398e-11 64.0 COG2266@1|root,COG2266@2|Bacteria,1RFQ8@1224|Proteobacteria,2UB5B@28211|Alphaproteobacteria,2K4C4@204457|Sphingomonadales 204457|Sphingomonadales H MobA-like NTP transferase domain - - - - - - - - - - - - NTP_transf_3 PJD2_k127_5300518_4 291985.CCSI01000001_gene2442 6.076e-95 315.0 COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2U66N@28211|Alphaproteobacteria,2K411@204457|Sphingomonadales 204457|Sphingomonadales Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 PJD2_k127_5300518_1 685035.ADAE01000018_gene429 0.0 1032.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria,2K00N@204457|Sphingomonadales 204457|Sphingomonadales J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 PJD2_k127_5300518_3 314225.ELI_06765 5.81e-116 379.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,2K2BU@204457|Sphingomonadales 204457|Sphingomonadales M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 PJD2_k127_5300518_0 1219035.NT2_02_00560 0.0 1241.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,2K0P9@204457|Sphingomonadales 204457|Sphingomonadales M Penicillin-binding Protein - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase PJD2_k127_5300518_5 1096930.L284_20245 1.793e-62 224.0 COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,2U9FF@28211|Alphaproteobacteria,2K56N@204457|Sphingomonadales 204457|Sphingomonadales O Peroxiredoxin - - - - - - - - - - - - AhpC-TSA PJD2_k127_5300518_2 1219035.NT2_02_00540 1.827e-197 619.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,2K0B2@204457|Sphingomonadales 204457|Sphingomonadales J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 PJD2_k127_5352262_3 383381.EH30_14310 9.308e-43 163.0 COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,2TV2J@28211|Alphaproteobacteria,2KDNP@204457|Sphingomonadales 204457|Sphingomonadales S oligosaccharyl transferase activity - - - - - - - - - - - - - PJD2_k127_5352262_1 1219035.NT2_04_04030 7.453e-139 451.0 COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2UBNR@28211|Alphaproteobacteria,2KCZE@204457|Sphingomonadales 204457|Sphingomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 PJD2_k127_5352262_0 702113.PP1Y_AT477 0.0 1623.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2K0BI@204457|Sphingomonadales 204457|Sphingomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran PJD2_k127_5352262_2 291985.CCSI01000002_gene1367 1.545e-52 200.0 COG2733@1|root,COG2733@2|Bacteria,1MX3G@1224|Proteobacteria,2U15J@28211|Alphaproteobacteria,2K0FY@204457|Sphingomonadales 204457|Sphingomonadales S membrane - - - - - - - - - - - - DUF445 PJD2_k127_5363035_2 314225.ELI_09875 4.994e-50 188.0 COG3713@1|root,COG3713@2|Bacteria,1RF1U@1224|Proteobacteria,2U8SJ@28211|Alphaproteobacteria,2K4FB@204457|Sphingomonadales 204457|Sphingomonadales M MltA-interacting protein MipA - - - - - - - - - - - - MipA PJD2_k127_5363035_1 685035.ADAE01000008_gene3051 2.839e-155 499.0 COG0654@1|root,COG0654@2|Bacteria,1N8DE@1224|Proteobacteria,2TU88@28211|Alphaproteobacteria,2K0B6@204457|Sphingomonadales 204457|Sphingomonadales CH Lycopene cyclase protein - - 5.5.1.19 ko:K06443 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R03824,R04801,R05341,R06962,R07856 RC01004,RC01964 ko00000,ko00001,ko00002,ko01000 - - - Lycopene_cycl PJD2_k127_5363035_0 291985.CCSI01000003_gene246 8.422e-270 840.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2K17H@204457|Sphingomonadales 204457|Sphingomonadales Q Phytoene dehydrogenase crtI - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase PJD2_k127_5417156_0 1144305.PMI02_01810 3.019e-253 793.0 COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,2TUPF@28211|Alphaproteobacteria,2K0U6@204457|Sphingomonadales 204457|Sphingomonadales M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_5417156_1 279238.Saro_0741 1.031e-61 216.0 COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,2TUGF@28211|Alphaproteobacteria,2K1RD@204457|Sphingomonadales 204457|Sphingomonadales G beta-1,4-mannooligosaccharide phosphorylase - - - - - - - - - - - - Glyco_hydro_130 PJD2_k127_5556792_4 1219045.BV98_003857 2.841e-89 299.0 COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,2U4DF@28211|Alphaproteobacteria,2K18I@204457|Sphingomonadales 204457|Sphingomonadales S LVIVD repeat - - - - - - - - - - - - LVIVD PJD2_k127_5556792_0 1088721.NSU_1239 5.4e-323 996.0 COG3827@1|root,COG3827@2|Bacteria,1QQR0@1224|Proteobacteria,2U38X@28211|Alphaproteobacteria,2K2AW@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_5556792_5 279238.Saro_2562 8.628e-76 260.0 2AB1F@1|root,310F3@2|Bacteria,1R7ZR@1224|Proteobacteria,2TTWQ@28211|Alphaproteobacteria,2K0R6@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - DUF4331 PJD2_k127_5556792_6 1123269.NX02_13440 8.23e-55 206.0 29WZ9@1|root,30IMG@2|Bacteria,1MXG3@1224|Proteobacteria,2U1X3@28211|Alphaproteobacteria,2K0FH@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - DUF4331 PJD2_k127_5556792_7 279238.Saro_2564 2.91e-45 186.0 COG0457@1|root,COG0457@2|Bacteria,1R530@1224|Proteobacteria,2TWPW@28211|Alphaproteobacteria,2K34N@204457|Sphingomonadales 204457|Sphingomonadales S Tetratricopeptide repeat - - - - - - - - - - - - - PJD2_k127_5556792_1 279238.Saro_2376 6.137e-278 869.0 COG3193@1|root,COG3193@2|Bacteria,1R3RC@1224|Proteobacteria,2U39K@28211|Alphaproteobacteria,2K2UI@204457|Sphingomonadales 204457|Sphingomonadales S Haem-degrading - - - - - - - - - - - - Haem_degrading PJD2_k127_5556792_2 1248917.ANFX01000012_gene1788 1.041e-182 582.0 COG3391@1|root,COG3391@2|Bacteria,1MXXH@1224|Proteobacteria,2TW31@28211|Alphaproteobacteria,2K2PG@204457|Sphingomonadales 204457|Sphingomonadales S Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554 PJD2_k127_5556792_3 1088721.NSU_1236 3.754e-181 635.0 COG3210@1|root,COG3210@2|Bacteria,1R8TG@1224|Proteobacteria,2U41V@28211|Alphaproteobacteria,2K1DN@204457|Sphingomonadales 204457|Sphingomonadales U COG3210 Large exoproteins involved in heme utilization or adhesion - - - - - - - - - - - - Haemagg_act PJD2_k127_5585638_3 161528.ED21_21979 2.703e-33 132.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2K27B@204457|Sphingomonadales 204457|Sphingomonadales I acetyl propionyl-CoA carboxylase, alpha subunit - - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 PJD2_k127_5585638_0 1122970.AUHC01000002_gene1457 1.062e-290 903.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,2K212@204457|Sphingomonadales 204457|Sphingomonadales I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans PJD2_k127_5585638_2 1044.EH31_05935 2.772e-143 468.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,2K0JH@204457|Sphingomonadales 204457|Sphingomonadales EGP Major facilitator superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 PJD2_k127_5585638_1 161528.ED21_21964 7.62e-154 496.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,2K1Q4@204457|Sphingomonadales 204457|Sphingomonadales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH PJD2_k127_5628480_2 314225.ELI_06070 1.193e-190 602.0 COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,2TU16@28211|Alphaproteobacteria,2K0ET@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF3376) - - - - - - - - - - - - DUF3376,Patatin PJD2_k127_5628480_1 291985.CCSI01000001_gene2319 5.857e-244 759.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,2K1F3@204457|Sphingomonadales 204457|Sphingomonadales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI PJD2_k127_5628480_3 314225.ELI_06080 2.894e-56 207.0 COG1286@1|root,COG1286@2|Bacteria,1REF7@1224|Proteobacteria,2VA4D@28211|Alphaproteobacteria,2K52S@204457|Sphingomonadales 204457|Sphingomonadales S Colicin V production protein - - - ko:K03558 - - - - ko00000 - - - Colicin_V PJD2_k127_5628480_5 1144305.PMI02_01304 6.28e-38 147.0 COG0822@1|root,COG0822@2|Bacteria,1RDGB@1224|Proteobacteria,2U74A@28211|Alphaproteobacteria,2K54B@204457|Sphingomonadales 204457|Sphingomonadales C NifU homolog involved in Fe-S cluster formation - - - - - - - - - - - - NifU_N PJD2_k127_5628480_0 1248917.ANFX01000008_gene246 6.087e-268 833.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TRAP@28211|Alphaproteobacteria,2K0IY@204457|Sphingomonadales 204457|Sphingomonadales EGP Major Facilitator - - - - - - - - - - - - MFS_1,Sugar_tr PJD2_k127_5628480_4 1122612.AUBA01000005_gene2819 5.267e-39 147.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,2K0BU@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N PJD2_k127_5739491_0 314225.ELI_01085 2.167e-244 762.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria,2K0SQ@204457|Sphingomonadales 204457|Sphingomonadales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 PJD2_k127_5739491_3 314225.ELI_01090 9.923e-71 247.0 COG3942@1|root,COG3942@2|Bacteria,1N0K8@1224|Proteobacteria,2UDGN@28211|Alphaproteobacteria,2K5G2@204457|Sphingomonadales 204457|Sphingomonadales S CHAP domain - - - - - - - - - - - - CHAP PJD2_k127_5739491_4 1479239.JQMU01000001_gene1947 2.229e-43 160.0 2CC0C@1|root,32RUG@2|Bacteria,1MZVQ@1224|Proteobacteria,2UBWU@28211|Alphaproteobacteria,2K606@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF3297) - - - - - - - - - - - - DUF3297 PJD2_k127_5739491_6 1120963.KB894491_gene1107 6.293e-05 55.0 2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_5739491_1 314225.ELI_01110 1.774e-208 658.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria,2K02U@204457|Sphingomonadales 204457|Sphingomonadales D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N PJD2_k127_5739491_2 279238.Saro_3057 4.742e-97 324.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TV11@28211|Alphaproteobacteria,2K0M0@204457|Sphingomonadales 204457|Sphingomonadales J Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase PJD2_k127_5768940_3 314225.ELI_02040 8.373e-55 205.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,2K5QM@204457|Sphingomonadales 204457|Sphingomonadales CO Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin PJD2_k127_5768940_0 1248917.ANFX01000022_gene690 3.683e-240 753.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,2K185@204457|Sphingomonadales 204457|Sphingomonadales E argininosuccinate lyase argH - 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 PJD2_k127_5768940_5 291985.CCSI01000004_gene705 5.522e-22 104.0 293KA@1|root,2ZR29@2|Bacteria,1NKAC@1224|Proteobacteria,2UK1U@28211|Alphaproteobacteria,2K6TK@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_5768940_1 291985.CCSI01000004_gene704 8.83e-221 689.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,2JZWD@204457|Sphingomonadales 204457|Sphingomonadales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC PJD2_k127_5768940_2 291985.CCSI01000004_gene703 1.958e-85 299.0 COG1648@1|root,COG1648@2|Bacteria,1RFEE@1224|Proteobacteria,2U6CW@28211|Alphaproteobacteria,2K2V1@204457|Sphingomonadales 204457|Sphingomonadales H Siroheme synthase - - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7 PJD2_k127_5768940_4 1479239.JQMU01000001_gene359 7.505e-33 128.0 COG0745@1|root,COG0745@2|Bacteria,1QU38@1224|Proteobacteria,2TVXD@28211|Alphaproteobacteria,2KAIR@204457|Sphingomonadales 204457|Sphingomonadales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg PJD2_k127_5797423_0 317655.Sala_2235 2.053e-142 461.0 COG2244@1|root,COG2244@2|Bacteria,1RC9S@1224|Proteobacteria,2U63T@28211|Alphaproteobacteria,2K3HG@204457|Sphingomonadales 204457|Sphingomonadales S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3 PJD2_k127_5797423_2 926562.Oweho_1051 2.16e-24 114.0 COG2020@1|root,COG2020@2|Bacteria,4NJCI@976|Bacteroidetes,1I1CA@117743|Flavobacteriia,2PBU6@246874|Cryomorphaceae 976|Bacteroidetes O PFAM Isoprenylcysteine carboxyl methyltransferase - - - - - - - - - - - - PEMT PJD2_k127_5797423_1 158500.BV97_02922 4.064e-54 198.0 COG0125@1|root,COG0125@2|Bacteria,1R4NC@1224|Proteobacteria,2VGKR@28211|Alphaproteobacteria,2KE4K@204457|Sphingomonadales 204457|Sphingomonadales F ATP binding - - - - - - - - - - - - - PJD2_k127_5797423_3 1207055.C100_20355 1.713e-12 70.0 COG2266@1|root,COG2266@2|Bacteria,1RFQ8@1224|Proteobacteria,2U7WE@28211|Alphaproteobacteria,2KEM1@204457|Sphingomonadales 204457|Sphingomonadales H MobA-like NTP transferase domain - - - - - - - - - - - - NTP_transf_3 PJD2_k127_5838408_2 1134912.AJTV01000027_gene2611 9.898e-83 280.0 COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,2U45H@28211|Alphaproteobacteria 28211|Alphaproteobacteria H RibD C-terminal domain - - - - - - - - - - - - RibD_C PJD2_k127_5838408_4 859657.RPSI07_mp1452 7.45e-80 269.0 COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VKXG@28216|Betaproteobacteria,1K6YB@119060|Burkholderiaceae 28216|Betaproteobacteria S 3-Demethylubiquinone-9 3-methyltransferase - - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - 3-dmu-9_3-mt PJD2_k127_5838408_1 1174684.EBMC1_11605 5.071e-91 309.0 COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,2K4NC@204457|Sphingomonadales 204457|Sphingomonadales S enzyme related to lactoylglutathione lyase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase PJD2_k127_5838408_7 383381.EH30_02790 3.883e-45 166.0 COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria,2K5Z8@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1428) - - - - - - - - - - - - DUF1428 PJD2_k127_5838408_3 1088721.NSU_4078 4.466e-80 273.0 COG0625@1|root,COG0625@2|Bacteria,1NE6Z@1224|Proteobacteria,2TVN6@28211|Alphaproteobacteria,2K4P4@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N,GST_N_3 PJD2_k127_5838408_5 291985.CCSI01000004_gene827 9.016e-78 266.0 COG1733@1|root,COG1733@2|Bacteria,1R6MK@1224|Proteobacteria,2U2KM@28211|Alphaproteobacteria,2K4SU@204457|Sphingomonadales 204457|Sphingomonadales K HxlR-like helix-turn-helix - - - - - - - - - - - - Alkyl_sulf_C,HxlR,SCP2 PJD2_k127_5838408_0 314225.ELI_02665 8.542e-118 384.0 COG3662@1|root,COG3662@2|Bacteria,1R50Q@1224|Proteobacteria,2TSG5@28211|Alphaproteobacteria,2K0BR@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF2236 PJD2_k127_5838408_6 161528.ED21_24681 6.54e-72 244.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,2K0S6@204457|Sphingomonadales 204457|Sphingomonadales S Aerobic cobaltochelatase subunit CobS - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5,CbbQ_C,CobS_N PJD2_k127_5849971_4 314225.ELI_12370 3.756e-197 618.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,2K14B@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD PJD2_k127_5849971_3 517722.AEUE01000001_gene2523 3.113e-198 642.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2U0FQ@28211|Alphaproteobacteria,2K06C@204457|Sphingomonadales 204457|Sphingomonadales P Alkaline phosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N PJD2_k127_5849971_19 1537715.JQFJ01000002_gene1208 7.501e-41 153.0 2C91B@1|root,33D4Z@2|Bacteria,1NG8C@1224|Proteobacteria,2UIXT@28211|Alphaproteobacteria,2K71B@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_5849971_13 161528.ED21_18777 1.677e-104 347.0 COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,2K1F6@204457|Sphingomonadales 204457|Sphingomonadales S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 PJD2_k127_5849971_18 158500.BV97_02277 1.107e-47 182.0 COG0457@1|root,COG0457@2|Bacteria,1MYZ1@1224|Proteobacteria,2UCPV@28211|Alphaproteobacteria,2K4IW@204457|Sphingomonadales 204457|Sphingomonadales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 PJD2_k127_5849971_8 1479239.JQMU01000001_gene1250 2.454e-158 505.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2TTR7@28211|Alphaproteobacteria,2K0NV@204457|Sphingomonadales 204457|Sphingomonadales C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase PJD2_k127_5849971_0 291985.CCSI01000002_gene1563 0.0 2021.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2K0WP@204457|Sphingomonadales 204457|Sphingomonadales E glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH PJD2_k127_5849971_5 1219035.NT2_04_01750 2.144e-186 592.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,2K12H@204457|Sphingomonadales 204457|Sphingomonadales S pyridine nucleotide-disulfide oxidoreductase - - 1.18.1.3 ko:K00529 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2,Reductase_C PJD2_k127_5849971_9 1044.EH31_15720 3.977e-156 517.0 COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2TVJ9@28211|Alphaproteobacteria,2K2BY@204457|Sphingomonadales 204457|Sphingomonadales C acyl-CoA transferases carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 PJD2_k127_5849971_6 314225.ELI_12430 1.465e-166 529.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,2K0HW@204457|Sphingomonadales 204457|Sphingomonadales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 PJD2_k127_5849971_10 314225.ELI_12435 9.83e-155 514.0 COG4152@1|root,COG4152@2|Bacteria,1QUPV@1224|Proteobacteria,2TW40@28211|Alphaproteobacteria,2JZWA@204457|Sphingomonadales 204457|Sphingomonadales S ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran PJD2_k127_5849971_12 517722.AEUE01000001_gene2517 1.006e-111 388.0 COG1668@1|root,COG1668@2|Bacteria,1MWAS@1224|Proteobacteria,2TU2K@28211|Alphaproteobacteria,2K1E9@204457|Sphingomonadales 204457|Sphingomonadales CP ABC-type Na efflux pump, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 PJD2_k127_5849971_1 1248917.ANFX01000013_gene1561 4.84e-224 701.0 COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TRWW@28211|Alphaproteobacteria,2K1ZZ@204457|Sphingomonadales 204457|Sphingomonadales Q cytochrome P450 - - - - - - - - - - - - p450 PJD2_k127_5849971_16 702113.PP1Y_AT2044 3.666e-71 254.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4P6@204457|Sphingomonadales 204457|Sphingomonadales O conserved domain frequently associated with peptide methionine sulfoxide reductase - - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR PJD2_k127_5849971_20 161528.ED21_19777 2.088e-35 141.0 COG2261@1|root,COG2261@2|Bacteria,1N8B3@1224|Proteobacteria,2UKNY@28211|Alphaproteobacteria,2K64H@204457|Sphingomonadales 204457|Sphingomonadales S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc PJD2_k127_5849971_17 314225.ELI_13475 4.005e-53 187.0 2AMHV@1|root,31CDG@2|Bacteria,1RGVA@1224|Proteobacteria,2U98Q@28211|Alphaproteobacteria,2K54G@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1153) - - - - - - - - - - - - DUF1153 PJD2_k127_5849971_2 1248917.ANFX01000026_gene1050 5.258e-199 631.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria,2K1HV@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans PJD2_k127_5849971_21 161528.ED21_19757 3.336e-30 123.0 COG1680@1|root,COG1680@2|Bacteria,1NDM0@1224|Proteobacteria,2UIS6@28211|Alphaproteobacteria,2KEFZ@204457|Sphingomonadales 204457|Sphingomonadales V COG1680 Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - - PJD2_k127_5849971_7 314225.ELI_13450 6.509e-163 520.0 COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2TYCG@28211|Alphaproteobacteria,2K2G5@204457|Sphingomonadales 204457|Sphingomonadales V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase PJD2_k127_5849971_14 1123270.ATUR01000008_gene401 2.221e-90 322.0 COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,2U4TZ@28211|Alphaproteobacteria,2K01E@204457|Sphingomonadales 204457|Sphingomonadales S PhzC PhzF - - - - - - - - - - - - PhzC-PhzF PJD2_k127_5849971_11 555793.WSK_3663 4.864e-122 407.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria,2K09U@204457|Sphingomonadales 204457|Sphingomonadales P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family fieF - - ko:K13283 - - - - ko00000,ko02000 2.A.4.7.1 - - Cation_efflux,ZT_dimer PJD2_k127_5849971_15 517722.AEUE01000005_gene2002 3.692e-88 294.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2K0J3@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx PJD2_k127_5849971_22 1219035.NT2_04_03950 5.568e-20 89.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2K1JP@204457|Sphingomonadales 204457|Sphingomonadales O molecular chaperone dnaJ_2 - - - - - - - - - - - DnaJ,DnaJ_C PJD2_k127_5851341_5 314225.ELI_02900 1.296e-145 469.0 COG2020@1|root,COG2020@2|Bacteria,1R55E@1224|Proteobacteria,2U75X@28211|Alphaproteobacteria,2K0AU@204457|Sphingomonadales 204457|Sphingomonadales O protein-S-isoprenylcysteine methyltransferase - - - - - - - - - - - - DUF1295,ICMT PJD2_k127_5851341_2 383381.EH30_03040 7.845e-193 617.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,2K0GW@204457|Sphingomonadales 204457|Sphingomonadales S Pyrrolo-quinoline quinone - - - - - - - - - - - - PQQ_2,PQQ_3 PJD2_k127_5851341_9 314225.ELI_02890 4.211e-73 255.0 COG4649@1|root,COG4649@2|Bacteria,1P2GI@1224|Proteobacteria,2UCFZ@28211|Alphaproteobacteria,2K40C@204457|Sphingomonadales 204457|Sphingomonadales S Tetratricopeptide repeat-like domain - - - - - - - - - - - - TPR_21 PJD2_k127_5851341_4 314225.ELI_02885 1.166e-150 494.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2U43G@28211|Alphaproteobacteria,2K0KR@204457|Sphingomonadales 204457|Sphingomonadales M Glycosyl transferase family 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 PJD2_k127_5851341_8 314225.ELI_02880 7.275e-109 369.0 COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2TT0S@28211|Alphaproteobacteria,2K14Q@204457|Sphingomonadales 204457|Sphingomonadales S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 PJD2_k127_5851341_1 314225.ELI_02875 9.307e-219 701.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,2JZUT@204457|Sphingomonadales 204457|Sphingomonadales S Uncharacterized ACR, YdiU/UPF0061 family - - - - - - - - - - - - UPF0061 PJD2_k127_5851341_0 279238.Saro_0939 1.621e-246 767.0 COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,2TU8S@28211|Alphaproteobacteria,2K13M@204457|Sphingomonadales 204457|Sphingomonadales C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate astD - 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 - R05049 RC00080 ko00000,ko00001,ko01000 - - - Aldedh PJD2_k127_5851341_15 1219035.NT2_01_04140 8.874e-33 138.0 2AKPD@1|root,31BG1@2|Bacteria,1N1HV@1224|Proteobacteria,2UEQ0@28211|Alphaproteobacteria,2K577@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_5851341_13 279238.Saro_0937 1.113e-36 143.0 COG3134@1|root,COG3134@2|Bacteria,1NXRT@1224|Proteobacteria,2UTMM@28211|Alphaproteobacteria,2KAV6@204457|Sphingomonadales 204457|Sphingomonadales S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti PJD2_k127_5851341_6 237727.NAP1_02150 3.588e-117 385.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2TV8D@28211|Alphaproteobacteria,2K1SV@204457|Sphingomonadales 204457|Sphingomonadales S RarD protein - - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA PJD2_k127_5851341_3 517722.AEUE01000007_gene438 9.789e-157 500.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2TT2U@28211|Alphaproteobacteria,2K057@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 PJD2_k127_5851341_7 314225.ELI_02835 1.75e-110 362.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,2K18B@204457|Sphingomonadales 204457|Sphingomonadales S Aminomethyltransferase - - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T PJD2_k127_5851341_12 1219035.NT2_10_00870 4.941e-41 159.0 COG3650@1|root,COG3650@2|Bacteria,1N3AW@1224|Proteobacteria,2UDVE@28211|Alphaproteobacteria,2KCD9@204457|Sphingomonadales 204457|Sphingomonadales S response to hydrogen peroxide - - - - - - - - - - - - - PJD2_k127_5851341_17 1044.EH31_03750 5.406e-17 82.0 29DN7@1|root,300K0@2|Bacteria,1P64V@1224|Proteobacteria,2UYQF@28211|Alphaproteobacteria,2KBXA@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_5851341_14 161528.ED21_21124 1.773e-33 129.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2K5Z5@204457|Sphingomonadales 204457|Sphingomonadales K Cold-shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD PJD2_k127_5851341_18 1144305.PMI02_00393 1.428e-12 73.0 2AE2V@1|root,313VV@2|Bacteria,1N8CN@1224|Proteobacteria,2UHK4@28211|Alphaproteobacteria,2K7AD@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_5851341_19 1479239.JQMU01000001_gene855 3.9e-11 66.0 2DCJU@1|root,2ZEF4@2|Bacteria,1P46H@1224|Proteobacteria,2UWRX@28211|Alphaproteobacteria,2KBW2@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_5851341_11 1219035.NT2_10_00910 2.517e-51 196.0 COG1881@1|root,COG1881@2|Bacteria,1RHPA@1224|Proteobacteria,2UMUY@28211|Alphaproteobacteria,2K4WS@204457|Sphingomonadales 204457|Sphingomonadales S Phosphatidylethanolamine-binding protein - - - - - - - - - - - - PBP PJD2_k127_5851341_10 314225.ELI_09775 5.508e-64 231.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2U997@28211|Alphaproteobacteria,2K4GS@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 PJD2_k127_5851341_16 1121124.JNIX01000008_gene2569 1.141e-21 98.0 COG2905@1|root,COG2905@2|Bacteria,1QZRP@1224|Proteobacteria,2TYD4@28211|Alphaproteobacteria,2KJW2@204458|Caulobacterales 204458|Caulobacterales T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS PJD2_k127_5852187_9 161528.ED21_31229 3.467e-16 78.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2U703@28211|Alphaproteobacteria,2K3XQ@204457|Sphingomonadales 204457|Sphingomonadales S Hydrolase - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 PJD2_k127_5852187_10 1088721.NSU_0672 2.473e-11 69.0 2AHV6@1|root,3187Z@2|Bacteria,1PB31@1224|Proteobacteria,2UX85@28211|Alphaproteobacteria,2K8C5@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_5852187_5 291985.CCSI01000003_gene106 1.865e-82 284.0 COG5387@1|root,COG5387@2|Bacteria,1Q3B5@1224|Proteobacteria,2TVK1@28211|Alphaproteobacteria,2K1FD@204457|Sphingomonadales 204457|Sphingomonadales O Chaperone required for the assembly of the mitochondrial F1-ATPase - - - - - - - - - - - - ATP12 PJD2_k127_5852187_8 1112212.JH584235_gene2978 5.013e-18 83.0 2AM77@1|root,31C1U@2|Bacteria,1Q803@1224|Proteobacteria,2VE5T@28211|Alphaproteobacteria,2K70R@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_5852187_1 1089551.KE386572_gene4365 2.579e-190 601.0 COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,2TS20@28211|Alphaproteobacteria,4BR85@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger PJD2_k127_5852187_6 314225.ELI_01315 6.116e-58 220.0 COG3218@1|root,COG3218@2|Bacteria,1RKTW@1224|Proteobacteria,2UAXY@28211|Alphaproteobacteria,2K5KR@204457|Sphingomonadales 204457|Sphingomonadales S transport system auxiliary component linN - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux PJD2_k127_5852187_3 314225.ELI_01310 7.666e-134 433.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,2K12E@204457|Sphingomonadales 204457|Sphingomonadales Q ABC-type transport system involved in resistance to organic solvents, periplasmic component - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD PJD2_k127_5852187_4 291985.CCSI01000003_gene111 1.23e-124 441.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2K11G@204457|Sphingomonadales 204457|Sphingomonadales Q ABC-type transport system involved in resistance to organic solvents, ATPase component - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran PJD2_k127_5852187_2 685035.ADAE01000018_gene1173 1.399e-144 471.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2K10W@204457|Sphingomonadales 204457|Sphingomonadales Q ABC-type transport system involved in resistance to organic solvents, permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE PJD2_k127_5852187_0 983920.Y88_3215 0.0 1515.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,2K0N3@204457|Sphingomonadales 204457|Sphingomonadales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 PJD2_k127_5852187_7 517722.AEUE01000008_gene236 2.182e-24 105.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,2K21H@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM PJD2_k127_5882653_2 161528.ED21_25422 1.44e-153 498.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,2K1MA@204457|Sphingomonadales 204457|Sphingomonadales O cytochrome C ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm PJD2_k127_5882653_8 1219035.NT2_01_03320 4.576e-57 206.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,2K56Y@204457|Sphingomonadales 204457|Sphingomonadales O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE - - ko:K02197 - - - - ko00000 - - - CcmE PJD2_k127_5882653_11 314225.ELI_03860 5.047e-09 67.0 2DHFP@1|root,2ZZJK@2|Bacteria,1P74G@1224|Proteobacteria,2UWNY@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_5882653_4 314225.ELI_03855 1.226e-108 362.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,2K13J@204457|Sphingomonadales 204457|Sphingomonadales O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm PJD2_k127_5882653_1 161528.ED21_25402 6.595e-175 556.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2K0AY@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N PJD2_k127_5882653_5 685035.ADAE01000020_gene1512 2.023e-92 308.0 COG3751@1|root,COG3751@2|Bacteria,1R9PW@1224|Proteobacteria,2TT9Q@28211|Alphaproteobacteria,2K2TP@204457|Sphingomonadales 204457|Sphingomonadales O oxygenase - - 1.14.11.2 ko:K00472 ko00330,ko01100,map00330,map01100 - R01252 RC00478 ko00000,ko00001,ko01000 - - - 2OG-FeII_Oxy_3 PJD2_k127_5882653_7 452652.KSE_71950 8.314e-60 217.0 COG2258@1|root,COG2258@2|Bacteria,2GMBE@201174|Actinobacteria,2M2TF@2063|Kitasatospora 201174|Actinobacteria S MOSC domain - - - - - - - - - - - - MOSC PJD2_k127_5882653_9 161528.ED21_25387 1.726e-38 145.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria,2K643@204457|Sphingomonadales 204457|Sphingomonadales J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 PJD2_k127_5882653_6 1248917.ANFX01000037_gene2164 1.353e-70 243.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria,2K4JA@204457|Sphingomonadales 204457|Sphingomonadales I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA PJD2_k127_5882653_10 1030157.AFMP01000062_gene3510 1.165e-35 143.0 COG2825@1|root,COG2825@2|Bacteria,1NNT2@1224|Proteobacteria 1224|Proteobacteria M Outer membrane chaperone Skp - - - ko:K06142 - - - - ko00000 - - - OmpH PJD2_k127_5882653_0 314225.ELI_03815 0.0 1212.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,2K0GI@204457|Sphingomonadales 204457|Sphingomonadales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA PJD2_k127_5882653_3 291985.CCSI01000001_gene1931 1.458e-149 482.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,2K0AZ@204457|Sphingomonadales 204457|Sphingomonadales M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 PJD2_k127_5901627_9 1122970.AUHC01000013_gene1004 4.31e-12 65.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,2K12I@204457|Sphingomonadales 204457|Sphingomonadales I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 PJD2_k127_5901627_1 314225.ELI_10045 3.151e-135 437.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2UVAZ@28211|Alphaproteobacteria,2K1F0@204457|Sphingomonadales 204457|Sphingomonadales I Belongs to the 3-hydroxyisobutyrate dehydrogenase family mmsB - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 PJD2_k127_5901627_3 1219035.NT2_05_03680 6.016e-114 373.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,2K1PD@204457|Sphingomonadales 204457|Sphingomonadales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC PJD2_k127_5901627_6 1219035.NT2_05_03670 1.254e-34 135.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2UF4Z@28211|Alphaproteobacteria,2K60Q@204457|Sphingomonadales 204457|Sphingomonadales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 PJD2_k127_5901627_8 314225.ELI_01595 2.266e-23 101.0 COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,2UFBN@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0003674,GO:0005215 - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 PJD2_k127_5901627_4 314225.ELI_01590 8.734e-91 317.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2TU64@28211|Alphaproteobacteria,2K231@204457|Sphingomonadales 204457|Sphingomonadales D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB PJD2_k127_5901627_2 314225.ELI_01585 5.328e-119 405.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2TS1V@28211|Alphaproteobacteria,2K15W@204457|Sphingomonadales 204457|Sphingomonadales D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA PJD2_k127_5901627_0 1144305.PMI02_03660 4.746e-154 494.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,2JZUV@204457|Sphingomonadales 204457|Sphingomonadales G beta-N-acetylhexosaminidase nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 PJD2_k127_5901627_5 314225.ELI_01575 1.237e-59 217.0 COG3115@1|root,COG3115@2|Bacteria,1RJNQ@1224|Proteobacteria,2UC30@28211|Alphaproteobacteria,2K2NX@204457|Sphingomonadales 204457|Sphingomonadales D Sporulation related domain - - - - - - - - - - - - SPOR PJD2_k127_5901627_7 517722.AEUE01000004_gene752 6.386e-32 125.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,2K0G5@204457|Sphingomonadales 204457|Sphingomonadales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1,tRNA-synt_1d,tRNA-synt_1f PJD2_k127_5911304_2 291985.CCSI01000003_gene166 2.51e-121 391.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2K0J0@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT PJD2_k127_5911304_1 1219035.NT2_01_04760 2.115e-159 510.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2TSVG@28211|Alphaproteobacteria,2K0AG@204457|Sphingomonadales 204457|Sphingomonadales E tRNA synthetase, class II hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His PJD2_k127_5911304_0 1123270.ATUR01000008_gene388 1.959e-263 815.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2TRKY@28211|Alphaproteobacteria,2K0T7@204457|Sphingomonadales 204457|Sphingomonadales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt PJD2_k127_5911304_4 383381.EH30_02100 1.176e-60 220.0 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2TS2U@28211|Alphaproteobacteria,2KA2Q@204457|Sphingomonadales 204457|Sphingomonadales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD PJD2_k127_5911304_3 1122612.AUBA01000004_gene482 1.966e-97 336.0 COG1846@1|root,COG1846@2|Bacteria,1N2Q4@1224|Proteobacteria,2UC5A@28211|Alphaproteobacteria,2K54U@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - - - - - - - - - - HTH_27,MarR PJD2_k127_5911304_6 1248917.ANFX01000041_gene1742 1.097e-29 121.0 COG0745@1|root,COG0745@2|Bacteria,1QU38@1224|Proteobacteria,2TVXD@28211|Alphaproteobacteria,2KAIR@204457|Sphingomonadales 204457|Sphingomonadales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg PJD2_k127_5963732_1 279238.Saro_0442 1.971e-129 428.0 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TSUC@28211|Alphaproteobacteria,2JZUS@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA PJD2_k127_5963732_0 1219035.NT2_04_04600 6.682e-297 914.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria,2K0N8@204457|Sphingomonadales 204457|Sphingomonadales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C PJD2_k127_5963732_2 1096930.L284_03745 6.98e-120 395.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TR5S@28211|Alphaproteobacteria,2K1R4@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - 1.1.1.276 ko:K05886 - - - - ko00000,ko01000 - - - adh_short PJD2_k127_5963732_3 685035.ADAE01000023_gene1702 1.226e-78 265.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria,2K02I@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind PJD2_k127_5969861_4 314225.ELI_03240 1.292e-112 371.0 COG2948@1|root,COG2948@2|Bacteria,1MXVX@1224|Proteobacteria,2TT9H@28211|Alphaproteobacteria,2K3H8@204457|Sphingomonadales 204457|Sphingomonadales U type IV secretion system protein - - - ko:K03195 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - TrbI PJD2_k127_5969861_2 1122970.AUHC01000004_gene2304 2.299e-174 563.0 COG0630@1|root,COG0630@2|Bacteria,1QUJ6@1224|Proteobacteria,2TW2D@28211|Alphaproteobacteria,2K02G@204457|Sphingomonadales 204457|Sphingomonadales NU IV secretion system protein - - - ko:K03196 ko03070,ko05120,map03070,map05120 M00333,M00564 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T2SSE PJD2_k127_5969861_1 1120705.FG95_03598 0.0 1067.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,1R479@1224|Proteobacteria,2UR59@28211|Alphaproteobacteria,2K9JT@204457|Sphingomonadales 204457|Sphingomonadales M COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_5969861_5 1120705.FG95_03598 2.323e-79 268.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,1R479@1224|Proteobacteria,2UR59@28211|Alphaproteobacteria,2K9JT@204457|Sphingomonadales 204457|Sphingomonadales M COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_5969861_3 1219035.NT2_01_06320 6.975e-136 434.0 COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2TTZV@28211|Alphaproteobacteria,2K1FS@204457|Sphingomonadales 204457|Sphingomonadales S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 PJD2_k127_5969861_7 748280.NH8B_1148 4.207e-06 49.0 2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - PJD2_k127_5969861_0 1336235.JAEG01000012_gene4143 0.0 1084.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR38@28211|Alphaproteobacteria,4B9IV@82115|Rhizobiaceae 28211|Alphaproteobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N PJD2_k127_5969861_6 279238.Saro_3585 2.048e-38 146.0 COG0845@1|root,COG0845@2|Bacteria,1Q10W@1224|Proteobacteria,2TSC8@28211|Alphaproteobacteria,2K9U3@204457|Sphingomonadales 204457|Sphingomonadales M HlyD family secretion protein - - - ko:K02005 - - - - ko00000 - - - HlyD_3 PJD2_k127_6016729_1 314225.ELI_02325 1.574e-115 375.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0T8@204457|Sphingomonadales 204457|Sphingomonadales T Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_6016729_0 1219035.NT2_02_02020 5.475e-186 589.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,2K062@204457|Sphingomonadales 204457|Sphingomonadales C NAD(P) transhydrogenase subunit alpha pntAA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N PJD2_k127_6016729_2 279238.Saro_1844 5.82e-46 167.0 COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2UBXS@28211|Alphaproteobacteria,2K5AR@204457|Sphingomonadales 204457|Sphingomonadales C nad(P) transhydrogenase subunit alpha pntAB - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM PJD2_k127_6016729_3 1088721.NSU_4121 3.73e-16 80.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,2K05C@204457|Sphingomonadales 204457|Sphingomonadales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB PJD2_k127_6018354_0 161528.ED21_24316 5.37e-144 462.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,2K0EE@204457|Sphingomonadales 204457|Sphingomonadales H dihydropteroate synthase folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind PJD2_k127_6018354_2 685035.ADAE01000018_gene990 1.943e-63 234.0 COG3945@1|root,COG3945@2|Bacteria,1RD5H@1224|Proteobacteria,2U8JH@28211|Alphaproteobacteria,2K4BE@204457|Sphingomonadales 204457|Sphingomonadales S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin PJD2_k127_6018354_1 383381.EH30_02375 2.271e-109 357.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0T8@204457|Sphingomonadales 204457|Sphingomonadales T Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_6047186_4 224911.27349670 3.347e-121 391.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,3JUU3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E B12 binding domain metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans PJD2_k127_6047186_2 1096930.L284_02145 1.873e-193 614.0 COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2UJRS@28211|Alphaproteobacteria,2K10F@204457|Sphingomonadales 204457|Sphingomonadales E Methionine synthase I (cobalamin-dependent), methyltransferase domain - - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - S-methyl_trans PJD2_k127_6047186_3 161528.ED21_21844 1.083e-153 492.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2TQZA@28211|Alphaproteobacteria,2K03Q@204457|Sphingomonadales 204457|Sphingomonadales E Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR PJD2_k127_6047186_5 702113.PP1Y_AT35019 4.896e-117 385.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,2TSMV@28211|Alphaproteobacteria,2K0VB@204457|Sphingomonadales 204457|Sphingomonadales K ArsR family transcriptional regulator - - - - - - - - - - - - HTH_20,HTH_5,Methyltransf_11 PJD2_k127_6047186_7 1219045.BV98_002245 2.749e-51 184.0 COG2346@1|root,COG2346@2|Bacteria,1MZSM@1224|Proteobacteria,2UCHK@28211|Alphaproteobacteria,2K5DI@204457|Sphingomonadales 204457|Sphingomonadales S COG2346 Truncated hemoglobins - - - ko:K06886 - - - - ko00000 - - - - PJD2_k127_6047186_8 392499.Swit_5296 2.279e-26 113.0 COG0784@1|root,COG0784@2|Bacteria,1NDF7@1224|Proteobacteria,2UII7@28211|Alphaproteobacteria,2K6SB@204457|Sphingomonadales 204457|Sphingomonadales T cheY-homologous receiver domain - - - - - - - - - - - - - PJD2_k127_6047186_1 1234595.C725_3010 2.683e-230 724.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,4BQ0I@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria T PAS domain fixL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_9 PJD2_k127_6047186_6 158500.BV97_04731 2.031e-94 315.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2TUND@28211|Alphaproteobacteria,2K3H2@204457|Sphingomonadales 204457|Sphingomonadales T helix_turn_helix, Lux Regulon - - - ko:K14987 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg PJD2_k127_6047186_9 1122970.AUHC01000001_gene663 1.46e-22 103.0 29DVJ@1|root,300TG@2|Bacteria,1P28D@1224|Proteobacteria,2UV6W@28211|Alphaproteobacteria,2K7B6@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_6047186_12 1449049.JONW01000011_gene2145 7.098e-10 67.0 2C12A@1|root,33B7C@2|Bacteria,1NMUW@1224|Proteobacteria,2UKV3@28211|Alphaproteobacteria,2KJIF@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - PJD2_k127_6047186_11 670292.JH26_20795 2.497e-17 86.0 2E40T@1|root,32YXK@2|Bacteria,1N95U@1224|Proteobacteria,2UH70@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_6047186_10 1449076.JOOE01000002_gene991 1.14e-19 93.0 2AEQ4@1|root,314KE@2|Bacteria,1P2CX@1224|Proteobacteria,2UUQX@28211|Alphaproteobacteria,2KBHE@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_6047186_0 279238.Saro_3493 1.09e-321 998.0 COG1511@1|root,COG2770@1|root,COG3437@1|root,COG5002@1|root,COG1511@2|Bacteria,COG2770@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWEB@28211|Alphaproteobacteria,2KEIX@204457|Sphingomonadales 204457|Sphingomonadales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - CHASE3,GAF_2,HATPase_c,HisKA,Response_reg PJD2_k127_6070389_4 1479239.JQMU01000001_gene179 2.832e-254 788.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TVC3@28211|Alphaproteobacteria,2K3AC@204457|Sphingomonadales 204457|Sphingomonadales I Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N PJD2_k127_6070389_14 291985.CCSI01000001_gene2530 4.899e-124 404.0 COG1073@1|root,COG1073@2|Bacteria,1QUNS@1224|Proteobacteria,2TW26@28211|Alphaproteobacteria,2K2SZ@204457|Sphingomonadales 204457|Sphingomonadales S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - 3.1.1.76 ko:K22250 - - - - ko00000,ko01000 - - - Abhydrolase_1 PJD2_k127_6070389_5 279238.Saro_1433 1.191e-218 684.0 COG0493@1|root,COG0493@2|Bacteria,1P58U@1224|Proteobacteria,2TUCG@28211|Alphaproteobacteria,2K06F@204457|Sphingomonadales 204457|Sphingomonadales E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases - - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - Pyr_redox_2 PJD2_k127_6070389_1 161528.ED21_28528 0.0 1073.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2JZXP@204457|Sphingomonadales 204457|Sphingomonadales Q COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - - - - - - - - - - Amidohydro_3 PJD2_k127_6070389_9 314225.ELI_07320 4.637e-164 521.0 COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2TTWF@28211|Alphaproteobacteria,2K2II@204457|Sphingomonadales 204457|Sphingomonadales C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - - - - - - - - - - ADH_N,ADH_zinc_N PJD2_k127_6070389_6 517722.AEUE01000007_gene264 9.151e-212 661.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,2K052@204457|Sphingomonadales 204457|Sphingomonadales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 PJD2_k127_6070389_12 314225.ELI_07335 7.277e-126 408.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,2K1MK@204457|Sphingomonadales 204457|Sphingomonadales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 PJD2_k127_6070389_10 1219035.NT2_02_03540 1.307e-151 490.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,2K15H@204457|Sphingomonadales 204457|Sphingomonadales I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 PJD2_k127_6070389_16 1219035.NT2_02_03550 1.555e-113 372.0 COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U0U5@28211|Alphaproteobacteria,2K08M@204457|Sphingomonadales 204457|Sphingomonadales V proteins, homologs of microcin C7 resistance protein MccF - - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 PJD2_k127_6070389_7 1219035.NT2_02_03560 1.277e-209 660.0 COG0773@1|root,COG0773@2|Bacteria,1MVCG@1224|Proteobacteria,2TTDN@28211|Alphaproteobacteria,2K0S4@204457|Sphingomonadales 204457|Sphingomonadales M UDP-N-acetylmuramate-alanine ligase - - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M PJD2_k127_6070389_13 1088721.NSU_0236 2.418e-124 411.0 COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2TU43@28211|Alphaproteobacteria,2K0C1@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - ko:K09781 - - - - ko00000 - - - DUF808 PJD2_k127_6070389_21 314225.ELI_07360 1.653e-60 211.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2U767@28211|Alphaproteobacteria,2K4F9@204457|Sphingomonadales 204457|Sphingomonadales J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 PJD2_k127_6070389_24 279238.Saro_1415 4.182e-37 140.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2UC13@28211|Alphaproteobacteria,2K5WV@204457|Sphingomonadales 204457|Sphingomonadales J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 PJD2_k127_6070389_19 685035.ADAE01000024_gene1849 1.945e-86 289.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2TSC9@28211|Alphaproteobacteria,2K0UT@204457|Sphingomonadales 204457|Sphingomonadales J Binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N PJD2_k127_6070389_3 291985.CCSI01000001_gene2571 2.376e-255 796.0 COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2TSX1@28211|Alphaproteobacteria,2K1YS@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations amn - 3.2.2.4 ko:K01241 ko00230,map00230 - R00182 RC00063,RC00318 ko00000,ko00001,ko01000 - - - AMNp_N,PNP_UDP_1 PJD2_k127_6070389_15 1120705.FG95_01487 8.265e-114 385.0 COG1028@1|root,COG1028@2|Bacteria,1MX8B@1224|Proteobacteria,2U26N@28211|Alphaproteobacteria,2K38N@204457|Sphingomonadales 204457|Sphingomonadales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 PJD2_k127_6070389_0 1248917.ANFX01000030_gene489 0.0 1074.0 COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,2TR6R@28211|Alphaproteobacteria,2K13P@204457|Sphingomonadales 204457|Sphingomonadales E Angiotensin-converting enzyme - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 PJD2_k127_6070389_18 1219035.NT2_02_03640 2.194e-102 340.0 COG2267@1|root,COG2267@2|Bacteria,1QUNU@1224|Proteobacteria,2TW29@28211|Alphaproteobacteria,2K09G@204457|Sphingomonadales 204457|Sphingomonadales I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 PJD2_k127_6070389_23 1096930.L284_04995 2.599e-56 199.0 COG3791@1|root,COG3791@2|Bacteria,1RE8S@1224|Proteobacteria,2U73V@28211|Alphaproteobacteria,2K4NT@204457|Sphingomonadales 204457|Sphingomonadales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA PJD2_k127_6070389_11 383381.EH30_07305 8.658e-142 458.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2K1WC@204457|Sphingomonadales 204457|Sphingomonadales V Secretion protein, HlyD - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 PJD2_k127_6070389_2 517722.AEUE01000007_gene246 2.904e-261 813.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,2JZYF@204457|Sphingomonadales 204457|Sphingomonadales EGP Major facilitator superfamily - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 PJD2_k127_6070389_17 685035.ADAE01000024_gene1861 1.223e-106 348.0 COG3917@1|root,COG3917@2|Bacteria,1MV6E@1224|Proteobacteria,2TVJ4@28211|Alphaproteobacteria,2K0YH@204457|Sphingomonadales 204457|Sphingomonadales Q 2-hydroxychromene-2-carboxylate isomerase - - - - - - - - - - - - DSBA PJD2_k127_6070389_8 1248917.ANFX01000030_gene481 1.365e-202 633.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,2K104@204457|Sphingomonadales 204457|Sphingomonadales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC PJD2_k127_6070389_22 1248760.ANFZ01000006_gene2497 3.799e-58 203.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria,2K4GC@204457|Sphingomonadales 204457|Sphingomonadales J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 PJD2_k127_6070389_20 237727.NAP1_06685 6.869e-65 223.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria,2JZVZ@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT PJD2_k127_6076979_1 1121033.AUCF01000026_gene2971 1.522e-104 347.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2TRKT@28211|Alphaproteobacteria,2JQTN@204441|Rhodospirillales 204441|Rhodospirillales H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - - - - - - - - - - - HemN_C,Radical_SAM PJD2_k127_6076979_0 1449076.JOOE01000001_gene2158 0.0 1150.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2K0F8@204457|Sphingomonadales 28211|Alphaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN PJD2_k127_6076979_2 13689.BV96_04645 4.711e-29 117.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2TSQ2@28211|Alphaproteobacteria,2K1GY@204457|Sphingomonadales 204457|Sphingomonadales P NnrS protein - - - - - - - - - - - - NnrS PJD2_k127_6077833_4 279238.Saro_2590 1.824e-20 93.0 COG3134@1|root,COG3134@2|Bacteria,1N5R8@1224|Proteobacteria,2UCFQ@28211|Alphaproteobacteria,2K6AP@204457|Sphingomonadales 204457|Sphingomonadales S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti PJD2_k127_6077833_3 555793.WSK_0498 9.106e-92 308.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,2K33T@204457|Sphingomonadales 204457|Sphingomonadales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 PJD2_k127_6077833_2 161528.ED21_26728 4.763e-99 328.0 COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,2U0ZF@28211|Alphaproteobacteria,2K0DE@204457|Sphingomonadales 204457|Sphingomonadales C Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) - - - - - - - - - - - - Ni_hydr_CYTB PJD2_k127_6077833_1 161528.ED21_26723 1.317e-108 356.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2TS40@28211|Alphaproteobacteria,2K206@204457|Sphingomonadales 204457|Sphingomonadales S COG2041 Sulfite oxidase and related enzymes - - - - - - - - - - - - Oxidored_molyb PJD2_k127_6077833_0 1219035.NT2_02_04410 6.278e-255 788.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,2K0AN@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth PJD2_k127_6115145_2 314225.ELI_03235 1.722e-97 326.0 COG3504@1|root,COG3504@2|Bacteria,1RASB@1224|Proteobacteria,2U5SW@28211|Alphaproteobacteria,2K4BJ@204457|Sphingomonadales 204457|Sphingomonadales U Conjugal transfer protein - - - ko:K03204 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - CagX PJD2_k127_6115145_1 314225.ELI_03230 8.616e-120 396.0 COG3704@1|root,COG3704@2|Bacteria,1R9F8@1224|Proteobacteria,2U0XT@28211|Alphaproteobacteria,2K3FA@204457|Sphingomonadales 204457|Sphingomonadales U TrbL/VirB6 plasmid conjugal transfer protein - - - ko:K03201 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - TrbL PJD2_k127_6115145_0 517722.AEUE01000007_gene480 4.554e-171 539.0 COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2TR1U@28211|Alphaproteobacteria,2K13S@204457|Sphingomonadales 204457|Sphingomonadales U type IV secretion system - - - ko:K03199 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - CagE_TrbE_VirB PJD2_k127_6159679_3 1479239.JQMU01000001_gene1337 2.294e-71 243.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,2K0GR@204457|Sphingomonadales 204457|Sphingomonadales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS PJD2_k127_6159679_2 291985.CCSI01000002_gene1354 1.246e-82 277.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,2K0M2@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase PJD2_k127_6159679_4 1122970.AUHC01000010_gene1549 1.865e-64 232.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,2K0M2@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase PJD2_k127_6159679_0 517722.AEUE01000002_gene2125 4.37e-181 582.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2K0NN@204457|Sphingomonadales 204457|Sphingomonadales E Membrane dipeptidase (Peptidase family M19) - - - - - - - - - - - - Peptidase_M19 PJD2_k127_6159679_5 1219035.NT2_04_04170 2.71e-63 223.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2U9GC@28211|Alphaproteobacteria,2K4ET@204457|Sphingomonadales 204457|Sphingomonadales H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 PJD2_k127_6159679_1 1219035.NT2_04_04180 1.122e-123 402.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2TRSV@28211|Alphaproteobacteria,2K0ZI@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp PJD2_k127_6205200_0 383381.EH30_06065 1.787e-280 873.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,2K0KI@204457|Sphingomonadales 204457|Sphingomonadales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - RNB,S1 PJD2_k127_6205200_1 161528.ED21_27533 1.058e-202 639.0 COG2234@1|root,COG2234@2|Bacteria,1MWBX@1224|Proteobacteria,2U2RE@28211|Alphaproteobacteria,2JZWX@204457|Sphingomonadales 204457|Sphingomonadales S Peptidase, M28 - - - - - - - - - - - - Peptidase_M28 PJD2_k127_6205200_2 1219035.NT2_06_00040 2.829e-81 274.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,2K1F1@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b PJD2_k127_6239874_2 517722.AEUE01000008_gene46 1.654e-184 587.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2TSIA@28211|Alphaproteobacteria,2K0U7@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,NusB PJD2_k127_6239874_6 291985.CCSI01000003_gene360 2.914e-16 80.0 COG5508@1|root,COG5508@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1674) - - - - - - - - - - - - DUF1674 PJD2_k127_6239874_1 1248917.ANFX01000050_gene637 1.85e-241 752.0 COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria,2K088@204457|Sphingomonadales 204457|Sphingomonadales Q Cytochrome p450 - - - - - - - - - - - - p450 PJD2_k127_6239874_3 291985.CCSI01000003_gene362 1.151e-165 527.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,2K0NQ@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase PJD2_k127_6239874_0 314225.ELI_11320 1.165e-283 899.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2K25R@204457|Sphingomonadales 204457|Sphingomonadales C aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 PJD2_k127_6239874_4 702113.PP1Y_AT33463 4.216e-127 422.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2K1RH@204457|Sphingomonadales 204457|Sphingomonadales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - ParA PJD2_k127_6239874_5 314225.ELI_11330 2.648e-27 121.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,2K20N@204457|Sphingomonadales 204457|Sphingomonadales O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 PJD2_k127_638870_5 685035.ADAE01000023_gene1702 3.891e-74 262.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria,2K02I@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind PJD2_k127_638870_0 291985.CCSI01000002_gene1298 9.635e-191 600.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria,2K0XB@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d PJD2_k127_638870_3 1219035.NT2_04_04540 1.649e-95 323.0 COG2207@1|root,COG2207@2|Bacteria,1RAXU@1224|Proteobacteria,2UQNW@28211|Alphaproteobacteria,2K8RN@204457|Sphingomonadales 204457|Sphingomonadales K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 PJD2_k127_638870_4 1120705.FG95_02383 3.313e-80 277.0 COG2207@1|root,COG2207@2|Bacteria,1RAXU@1224|Proteobacteria,2U682@28211|Alphaproteobacteria,2K33E@204457|Sphingomonadales 204457|Sphingomonadales K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 PJD2_k127_638870_6 237727.NAP1_12278 4.503e-59 206.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,2K4FX@204457|Sphingomonadales 204457|Sphingomonadales J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT - - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 PJD2_k127_638870_7 1248760.ANFZ01000002_gene2975 2.195e-34 132.0 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria,2K5YR@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the bacterial ribosomal protein bL35 family rpmI - - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p PJD2_k127_638870_2 161528.ED21_20094 4.956e-104 351.0 COG1028@1|root,COG1028@2|Bacteria,1MUAY@1224|Proteobacteria,2U6AS@28211|Alphaproteobacteria,2JZX9@204457|Sphingomonadales 204457|Sphingomonadales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 PJD2_k127_638870_1 314225.ELI_12100 1.358e-153 497.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Sulfatase PJD2_k127_684672_6 1502850.FG91_01392 7.287e-05 49.0 COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2U3CR@28211|Alphaproteobacteria,2K4EU@204457|Sphingomonadales 204457|Sphingomonadales G COG2513 PEP phosphonomutase and related enzymes - - - - - - - - - - - - PEP_mutase PJD2_k127_684672_2 685035.ADAE01000002_gene2468 1.272e-142 470.0 COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2K165@204457|Sphingomonadales 204457|Sphingomonadales FL Metal binding domain of Ada ada - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N PJD2_k127_684672_1 314225.ELI_08750 2.249e-173 559.0 COG0265@1|root,COG0265@2|Bacteria,1R5U1@1224|Proteobacteria,2U3GT@28211|Alphaproteobacteria,2KDBK@204457|Sphingomonadales 204457|Sphingomonadales O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - - - - - - - - - - Trypsin_2 PJD2_k127_684672_3 291985.CCSI01000005_gene875 1.105e-124 416.0 COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JZYD@204457|Sphingomonadales 204457|Sphingomonadales Q dioxygenase - - - ko:K22303 - - - - ko00000,ko01000 - - - TauD PJD2_k127_684672_4 314225.ELI_08765 3.939e-76 259.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,2K4UU@204457|Sphingomonadales 204457|Sphingomonadales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP PJD2_k127_684672_0 1545915.JROG01000003_gene889 2.578e-291 898.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,2K08A@204457|Sphingomonadales 204457|Sphingomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N PJD2_k127_684672_5 1144305.PMI02_02371 1.236e-41 155.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,2K0A5@204457|Sphingomonadales 204457|Sphingomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt PJD2_k127_692973_17 291985.CCSI01000001_gene2483 4.016e-95 314.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,2K010@204457|Sphingomonadales 204457|Sphingomonadales L Belongs to the DNA photolyase family phrB - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 PJD2_k127_692973_10 517722.AEUE01000004_gene1207 3.07e-189 600.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K1IB@204457|Sphingomonadales 204457|Sphingomonadales M synthase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS PJD2_k127_692973_12 685035.ADAE01000018_gene382 2.379e-152 492.0 COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,2TTI5@28211|Alphaproteobacteria,2K1R1@204457|Sphingomonadales 204457|Sphingomonadales V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase PJD2_k127_692973_20 161528.ED21_28283 2.846e-56 200.0 28YKP@1|root,2ZKEE@2|Bacteria,1NBD7@1224|Proteobacteria,2UHHD@28211|Alphaproteobacteria,2K531@204457|Sphingomonadales 204457|Sphingomonadales S Pilus assembly protein PilZ - - - - - - - - - - - - PilZ PJD2_k127_692973_16 314225.ELI_07020 2.557e-100 331.0 COG0300@1|root,COG0300@2|Bacteria,1QUNR@1224|Proteobacteria,2TW24@28211|Alphaproteobacteria,2K1AC@204457|Sphingomonadales 204457|Sphingomonadales S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short PJD2_k127_692973_2 314225.ELI_07015 2.498e-268 831.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2TR8V@28211|Alphaproteobacteria,2K0C0@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_7,Pribosyltran PJD2_k127_692973_6 314225.ELI_07010 8.359e-205 643.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,2K03V@204457|Sphingomonadales 204457|Sphingomonadales M ABC-type transport system, involved in lipoprotein release, permease component - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD PJD2_k127_692973_14 158500.BV97_01036 1.552e-112 367.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria,2K04P@204457|Sphingomonadales 204457|Sphingomonadales V Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran PJD2_k127_692973_18 161528.ED21_28248 2.62e-77 261.0 COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2U7R3@28211|Alphaproteobacteria,2K47B@204457|Sphingomonadales 204457|Sphingomonadales O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx PJD2_k127_692973_0 161528.ED21_28238 0.0 1790.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,2K1R8@204457|Sphingomonadales 204457|Sphingomonadales L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP PJD2_k127_692973_1 517722.AEUE01000004_gene1217 3.448e-275 865.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,2K0TE@204457|Sphingomonadales 204457|Sphingomonadales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.44 ko:K00666,ko:K20034 ko00920,map00920 - R10820 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - AMP-binding,AMP-binding_C PJD2_k127_692973_22 158500.BV97_00739 9.538e-48 172.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,2K2A3@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP PJD2_k127_692973_15 702113.PP1Y_AT25337 1.273e-110 361.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,2K2A3@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP PJD2_k127_692973_7 1090319.KE386571_gene982 2.384e-193 611.0 COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,2TUM5@28211|Alphaproteobacteria,2K1MY@204457|Sphingomonadales 204457|Sphingomonadales EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_3 PJD2_k127_692973_21 383381.EH30_05850 5.066e-53 188.0 2AI3K@1|root,318HD@2|Bacteria,1N501@1224|Proteobacteria,2UIA7@28211|Alphaproteobacteria,2KA7D@204457|Sphingomonadales 204457|Sphingomonadales S PilZ domain - - - - - - - - - - - - PilZ PJD2_k127_692973_5 1479239.JQMU01000001_gene2687 1.885e-213 672.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2TQPA@28211|Alphaproteobacteria,2K11C@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b PJD2_k127_692973_19 161528.ED21_27323 3.075e-72 247.0 2C0PI@1|root,32VVI@2|Bacteria,1N1H7@1224|Proteobacteria,2UE1P@28211|Alphaproteobacteria,2K60G@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_692973_4 685035.ADAE01000018_gene675 2.93e-223 698.0 COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2U1KM@28211|Alphaproteobacteria,2K0PB@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1343) - - - - - - - - - - - - DUF1343 PJD2_k127_692973_9 1248917.ANFX01000008_gene284 6.721e-190 604.0 COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,2U5M0@28211|Alphaproteobacteria,2KEAE@204457|Sphingomonadales 204457|Sphingomonadales EGP of the major facilitator superfamily - - - - - - - - - - - - MFS_1 PJD2_k127_692973_13 685035.ADAE01000018_gene677 3.026e-117 382.0 28NMK@1|root,2ZBN3@2|Bacteria,1R4AD@1224|Proteobacteria,2U00H@28211|Alphaproteobacteria,2KEWI@204457|Sphingomonadales 204457|Sphingomonadales U Pfam:DUF2837 - - - - - - - - - - - - Amj PJD2_k127_692973_24 685035.ADAE01000018_gene679 1.176e-17 87.0 2AS0P@1|root,31HD1@2|Bacteria,1PAGW@1224|Proteobacteria,2UWWU@28211|Alphaproteobacteria,2KBU1@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_692973_3 1248917.ANFX01000008_gene281 3.884e-242 751.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,2K0XS@204457|Sphingomonadales 204457|Sphingomonadales S Von Willebrand factor A - - - ko:K09989 - - - - ko00000 - - - VWA_CoxE PJD2_k127_692973_8 314225.ELI_05940 4.466e-193 612.0 COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,2TTNX@28211|Alphaproteobacteria,2K1FW@204457|Sphingomonadales 204457|Sphingomonadales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal PJD2_k127_692973_23 1174684.EBMC1_07150 8.382e-21 106.0 2BZTZ@1|root,2ZVGQ@2|Bacteria,1PAKI@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - PJD2_k127_692973_11 1479239.JQMU01000001_gene2694 2.677e-168 530.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TRI8@28211|Alphaproteobacteria,2JZXF@204457|Sphingomonadales 204457|Sphingomonadales S ATPase AAA - - - - - - - - - - - - AAA PJD2_k127_692973_25 517722.AEUE01000006_gene1847 6.247e-11 66.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,2K2F1@204457|Sphingomonadales 204457|Sphingomonadales O OsmC-like protein - - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC PJD2_k127_693439_2 314225.ELI_11355 4.113e-82 274.0 COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria,2K1DG@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 PJD2_k127_693439_1 517722.AEUE01000008_gene33 1.751e-227 713.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales 204457|Sphingomonadales C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh PJD2_k127_693439_0 1123267.JONN01000001_gene2463 5.944e-230 714.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria,2K04T@204457|Sphingomonadales 204457|Sphingomonadales C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily - - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N PJD2_k127_693439_4 1502850.FG91_03886 1.885e-56 199.0 COG0346@1|root,COG0346@2|Bacteria,1RH8G@1224|Proteobacteria,2U9BR@28211|Alphaproteobacteria,2K5AH@204457|Sphingomonadales 204457|Sphingomonadales E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase PJD2_k127_693439_3 1174684.EBMC1_17057 3.225e-74 256.0 COG3760@1|root,COG3760@2|Bacteria,1RDIG@1224|Proteobacteria,2U87T@28211|Alphaproteobacteria,2K54Z@204457|Sphingomonadales 204457|Sphingomonadales S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit PJD2_k127_693439_5 291985.CCSI01000007_gene535 2.765e-47 169.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,2K0BM@204457|Sphingomonadales 204457|Sphingomonadales J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 PJD2_k127_695137_5 1479239.JQMU01000001_gene746 9.159e-126 404.0 COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,2K07N@204457|Sphingomonadales 204457|Sphingomonadales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short PJD2_k127_695137_9 314225.ELI_08830 5.433e-55 199.0 2CCMQ@1|root,32RW3@2|Bacteria,1MZHB@1224|Proteobacteria,2UCC9@28211|Alphaproteobacteria,2K53Z@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF2794) - - - - - - - - - - - - DUF2794 PJD2_k127_695137_6 1122970.AUHC01000008_gene58 9.184e-116 376.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,2K2GH@204457|Sphingomonadales 204457|Sphingomonadales E serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep PJD2_k127_695137_8 1219035.NT2_01_01290 8.05e-76 261.0 COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria,2K4AT@204457|Sphingomonadales 204457|Sphingomonadales L ATPase involved in DNA replication - - - - - - - - - - - - Bac_DnaA PJD2_k127_695137_4 1122970.AUHC01000008_gene56 1.705e-137 464.0 COG3249@1|root,COG3249@2|Bacteria,1R81G@1224|Proteobacteria,2U1EP@28211|Alphaproteobacteria,2K0TT@204457|Sphingomonadales 204457|Sphingomonadales S protein conserved in bacteria - - - - - - - - - - - - - PJD2_k127_695137_1 383381.EH30_08705 2.555e-194 610.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,2K07H@204457|Sphingomonadales 204457|Sphingomonadales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C PJD2_k127_695137_3 1219035.NT2_01_01320 2.551e-144 465.0 COG0299@1|root,COG3801@1|root,COG0299@2|Bacteria,COG3801@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,2K28Q@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N,YjbR PJD2_k127_695137_11 234267.Acid_6972 2.005e-07 59.0 2E3YR@1|root,32YVP@2|Bacteria 2|Bacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 PJD2_k127_695137_7 1537715.JQFJ01000002_gene1071 5.193e-76 256.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,2K3WY@204457|Sphingomonadales 204457|Sphingomonadales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK PJD2_k127_695137_10 314225.ELI_08870 5.205e-40 153.0 COG2927@1|root,COG2927@2|Bacteria,1RGVC@1224|Proteobacteria,2U94V@28211|Alphaproteobacteria,2K5Y0@204457|Sphingomonadales 204457|Sphingomonadales L DNA polymerase III holC - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi PJD2_k127_695137_0 314225.ELI_08880 1.312e-221 696.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,2K04B@204457|Sphingomonadales 204457|Sphingomonadales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N PJD2_k127_695137_2 291985.CCSI01000005_gene848 5.17e-164 529.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,2K1GQ@204457|Sphingomonadales 204457|Sphingomonadales M Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C PJD2_k127_715254_0 291985.CCSI01000008_gene1081 0.0 1230.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,2K0F9@204457|Sphingomonadales 204457|Sphingomonadales L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB PJD2_k127_715254_2 1123267.JONN01000001_gene1975 9.509e-115 376.0 COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U69N@28211|Alphaproteobacteria,2KDKH@204457|Sphingomonadales 204457|Sphingomonadales S Methyltransferase - - - - - - - - - - - - Methyltransf_25,PCMT PJD2_k127_715254_1 1123270.ATUR01000003_gene1225 6.254e-247 770.0 COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2TS7R@28211|Alphaproteobacteria,2K0U5@204457|Sphingomonadales 204457|Sphingomonadales E peptidase S10 serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 PJD2_k127_715254_3 685035.ADAE01000002_gene2402 1.737e-39 157.0 2A23D@1|root,31BPS@2|Bacteria,1NEZ2@1224|Proteobacteria,2UIMC@28211|Alphaproteobacteria,2KDKX@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_715254_4 1335760.ASTG01000001_gene3072 1.811e-07 53.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,2K11D@204457|Sphingomonadales 204457|Sphingomonadales CO Thiol disulfide interchange protein - - - - - - - - - - - - DsbC,DsbD,Thioredoxin_7 PJD2_k127_732453_2 314225.ELI_09605 5.767e-225 700.0 COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TUVB@28211|Alphaproteobacteria,2K0FU@204457|Sphingomonadales 204457|Sphingomonadales I Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_732453_4 279238.Saro_0997 4.761e-194 616.0 COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2TVI8@28211|Alphaproteobacteria,2K092@204457|Sphingomonadales 204457|Sphingomonadales G COG2211 Na melibiose symporter and related transporters - - - - - - - - - - - - MFS_2 PJD2_k127_732453_1 237727.NAP1_10047 1.051e-226 729.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,2JZVP@204457|Sphingomonadales 204457|Sphingomonadales I acyl-CoA dehydrogenase - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_732453_5 1174684.EBMC1_04614 8.39e-191 600.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria,2K0RB@204457|Sphingomonadales 204457|Sphingomonadales C alcohol dehydrogenase - - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N PJD2_k127_732453_3 1120705.FG95_00016 2.286e-195 632.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria,2K142@204457|Sphingomonadales 204457|Sphingomonadales S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH PJD2_k127_732453_0 314225.ELI_09635 1.057e-249 793.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2U0VY@28211|Alphaproteobacteria,2K0U8@204457|Sphingomonadales 204457|Sphingomonadales O Subtilase family - - - - - - - - - - - - Peptidase_S8 PJD2_k127_732453_8 1248917.ANFX01000020_gene2254 1.973e-148 475.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2TS3H@28211|Alphaproteobacteria,2K055@204457|Sphingomonadales 204457|Sphingomonadales E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 PJD2_k127_732453_23 1081640.AGFU01000123_gene97 2.326e-23 103.0 2E3Y8@1|root,32YVA@2|Bacteria,1NAMJ@1224|Proteobacteria,2UF7H@28211|Alphaproteobacteria,2K76Z@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_732453_19 1470591.BW41_01226 3.008e-45 167.0 COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,2U9EH@28211|Alphaproteobacteria,2K605@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1810) - - - - - - - - - - - - DUF1810 PJD2_k127_732453_14 291985.CCSI01000006_gene1174 1.054e-59 216.0 COG1226@1|root,32YV7@2|Bacteria,1N7MV@1224|Proteobacteria,2UGX0@28211|Alphaproteobacteria,2KDAH@204457|Sphingomonadales 204457|Sphingomonadales P Ion channel - - - - - - - - - - - - Ion_trans_2 PJD2_k127_732453_6 1219035.NT2_10_00920 3.512e-177 565.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2K0GT@204457|Sphingomonadales 204457|Sphingomonadales E Zn-dependent dipeptidase, microsomal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 PJD2_k127_732453_12 1550073.JROH01000001_gene521 6.268e-84 289.0 COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,2TT1D@28211|Alphaproteobacteria,2K0SX@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 PJD2_k127_732453_15 1096930.L284_22810 1.433e-56 202.0 COG3871@1|root,COG3871@2|Bacteria,1RI2W@1224|Proteobacteria,2U9IM@28211|Alphaproteobacteria,2K4UQ@204457|Sphingomonadales 204457|Sphingomonadales S stress protein (general stress protein 26) - - - - - - - - - - - - Pyrid_ox_like PJD2_k127_732453_18 1502850.FG91_01339 1.759e-47 179.0 COG4270@1|root,COG4270@2|Bacteria,1N1BK@1224|Proteobacteria,2UD4E@28211|Alphaproteobacteria,2K595@204457|Sphingomonadales 204457|Sphingomonadales S DoxX-like family - - - - - - - - - - - - DoxX_2 PJD2_k127_732453_21 291985.CCSI01000006_gene1171 2.738e-36 138.0 COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2UHFX@28211|Alphaproteobacteria,2K6VN@204457|Sphingomonadales 204457|Sphingomonadales B COG5531 SWIB-domain-containing proteins implicated in chromatin remodeling - - - - - - - - - - - - SWIB PJD2_k127_732453_7 314225.ELI_09685 2.374e-176 564.0 COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,2U1FI@28211|Alphaproteobacteria,2K0WR@204457|Sphingomonadales 204457|Sphingomonadales M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 PJD2_k127_732453_11 161528.ED21_24851 8.359e-89 297.0 COG1309@1|root,COG1309@2|Bacteria,1N2ZP@1224|Proteobacteria,2UC9P@28211|Alphaproteobacteria,2K4HW@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - - - - - - - - - - TetR_N PJD2_k127_732453_9 314225.ELI_02825 8.34e-143 458.0 COG3687@1|root,COG3687@2|Bacteria,1MWGV@1224|Proteobacteria,2U1DK@28211|Alphaproteobacteria,2K0CB@204457|Sphingomonadales 204457|Sphingomonadales S Predicted metal-dependent hydrolase - - - ko:K07044 - - - - ko00000 - - - Metal_hydrol PJD2_k127_732453_13 291985.CCSI01000001_gene1832 8.24e-71 243.0 COG1670@1|root,COG1670@2|Bacteria,1N6Q1@1224|Proteobacteria,2UG72@28211|Alphaproteobacteria,2K4XG@204457|Sphingomonadales 204457|Sphingomonadales J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 PJD2_k127_732453_20 279238.Saro_0930 1.219e-44 162.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2UBUX@28211|Alphaproteobacteria,2K60H@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 PJD2_k127_732453_16 161528.ED21_24831 4.367e-56 203.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,2K5A0@204457|Sphingomonadales 204457|Sphingomonadales J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p PJD2_k127_732453_22 314225.ELI_02775 8.333e-28 119.0 2AMFW@1|root,31CBD@2|Bacteria,1NPT4@1224|Proteobacteria,2UMCJ@28211|Alphaproteobacteria,2K7Z7@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - PJD2_k127_732453_17 1144305.PMI02_03824 7.993e-55 195.0 COG1539@1|root,COG1539@2|Bacteria,1RKNS@1224|Proteobacteria,2UAD6@28211|Alphaproteobacteria,2K58X@204457|Sphingomonadales 204457|Sphingomonadales H dihydroneopterin aldolase - - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB PJD2_k127_732453_10 1219035.NT2_01_04320 4.684e-92 303.0 COG1092@1|root,COG1092@2|Bacteria,1QSD4@1224|Proteobacteria,2TUFT@28211|Alphaproteobacteria,2K037@204457|Sphingomonadales 204457|Sphingomonadales J Belongs to the methyltransferase superfamily - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM PJD2_k127_803904_0 1479239.JQMU01000001_gene881 7.268e-103 337.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTYY@28211|Alphaproteobacteria,2JZXZ@204457|Sphingomonadales 204457|Sphingomonadales S alcohol dehydrogenase - - - ko:K13979 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N PJD2_k127_803904_1 509190.Cseg_0615 1.477e-89 304.0 COG2267@1|root,COG2267@2|Bacteria,1R9GQ@1224|Proteobacteria,2U3YF@28211|Alphaproteobacteria,2KGD4@204458|Caulobacterales 204458|Caulobacterales I PFAM alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 PJD2_k127_803904_2 291985.CCSI01000003_gene258 1.257e-43 163.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,2K04G@204457|Sphingomonadales 204457|Sphingomonadales C Methylmalonate-semialdehyde dehydrogenase - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh PJD2_k127_82402_8 685035.ADAE01000004_gene1908 5.112e-25 106.0 29WPT@1|root,30IAR@2|Bacteria,1NDVR@1224|Proteobacteria,2UJ2P@28211|Alphaproteobacteria,2K5KW@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - GPDPase_memb PJD2_k127_82402_5 291985.CCSI01000003_gene208 4.254e-104 344.0 COG3963@1|root,COG3963@2|Bacteria,1R81B@1224|Proteobacteria,2U46R@28211|Alphaproteobacteria,2K2HK@204457|Sphingomonadales 204457|Sphingomonadales I Methyltransferase - - - - - - - - - - - - Methyltransf_25 PJD2_k127_82402_2 314225.ELI_00395 1.484e-192 610.0 COG0477@1|root,COG0477@2|Bacteria,1QUPF@1224|Proteobacteria,2U2HA@28211|Alphaproteobacteria,2K096@204457|Sphingomonadales 204457|Sphingomonadales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 PJD2_k127_82402_7 685035.ADAE01000004_gene1906 4.513e-49 177.0 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2U70U@28211|Alphaproteobacteria,2K5DH@204457|Sphingomonadales 204457|Sphingomonadales P arsenate reductase - - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC PJD2_k127_82402_0 314225.ELI_00385 1.677e-264 841.0 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2TVX5@28211|Alphaproteobacteria,2KED5@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - ko:K16090 - - - - ko00000,ko02000 1.B.14.1.11 - - Plug,TonB_dep_Rec PJD2_k127_82402_6 1088721.NSU_2470 1.982e-89 299.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2TVRA@28211|Alphaproteobacteria,2K405@204457|Sphingomonadales 204457|Sphingomonadales C aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 PJD2_k127_82402_4 1248917.ANFX01000029_gene2631 8.371e-127 409.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2K1HY@204457|Sphingomonadales 204457|Sphingomonadales G Aldolase - - - - - - - - - - - - Aldolase_II PJD2_k127_82402_3 1192759.AKIB01000014_gene1659 2.538e-135 439.0 2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,2TTDU@28211|Alphaproteobacteria,2K0FT@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF2891) - - - - - - - - - - - - DUF2891 PJD2_k127_82402_1 161528.ED21_22158 1.239e-257 814.0 COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,2K0Z1@204457|Sphingomonadales 204457|Sphingomonadales NT chemotaxis protein cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt PJD2_k127_906770_2 1219035.NT2_02_05040 1.23e-26 120.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,2K08N@204457|Sphingomonadales 204457|Sphingomonadales LU Rossmann fold nucleotide-binding protein involved in DNA uptake dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A PJD2_k127_906770_1 383381.EH30_04695 8.164e-66 242.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,2K0BP@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf PJD2_k127_906770_0 1096930.L284_23140 6.853e-108 355.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria,2K1X9@204457|Sphingomonadales 204457|Sphingomonadales M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race PJD2_k127_914278_2 1144305.PMI02_04704 8.628e-223 696.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,2K0R3@204457|Sphingomonadales 204457|Sphingomonadales H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase PJD2_k127_914278_8 745310.G432_12810 2.906e-54 206.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,2K4TF@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the CinA family - - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA PJD2_k127_914278_4 291985.CCSI01000001_gene2022 1.833e-157 503.0 COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2TUAH@28211|Alphaproteobacteria,2JZW2@204457|Sphingomonadales 204457|Sphingomonadales L DNA topoisomerase - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_I PJD2_k127_914278_5 158500.BV97_00968 4.22e-124 405.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTDF@28211|Alphaproteobacteria,2K19J@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase - - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N PJD2_k127_914278_3 1280954.HPO_05657 3.154e-161 512.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria 28211|Alphaproteobacteria I 2-nitropropane dioxygenase MA20_15180 - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO PJD2_k127_914278_7 983920.Y88_2503 3.824e-81 282.0 COG2207@1|root,COG2207@2|Bacteria,1N4K1@1224|Proteobacteria,2UF1F@28211|Alphaproteobacteria,2KDQH@204457|Sphingomonadales 204457|Sphingomonadales K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 PJD2_k127_914278_0 441620.Mpop_0149 2.676e-288 913.0 COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JQYU@119045|Methylobacteriaceae 28211|Alphaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg PJD2_k127_914278_1 450851.PHZ_c1128 5.728e-242 766.0 COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2TRV7@28211|Alphaproteobacteria,2KG8H@204458|Caulobacterales 204458|Caulobacterales IQ AMP-binding enzyme - - 6.2.1.34 ko:K12508 - - - - ko00000,ko01000 - - - AMP-binding PJD2_k127_914278_6 1449049.JONW01000011_gene2147 4.752e-94 314.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U0J1@28211|Alphaproteobacteria,2KHV7@204458|Caulobacterales 204458|Caulobacterales M TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_936039_6 314225.ELI_01540 1.2e-103 358.0 COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,2JZYS@204457|Sphingomonadales 204457|Sphingomonadales E Oxidoreductase - - 1.4.99.6 ko:K19746 ko00472,ko01100,map00472,map01100 - R11018 RC00006 ko00000,ko00001,ko01000 - - - DAO PJD2_k127_936039_4 314225.ELI_01535 1.607e-138 448.0 COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,2TSZ4@28211|Alphaproteobacteria,2K0NG@204457|Sphingomonadales 204457|Sphingomonadales I Lysophospholipase - - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 PJD2_k127_936039_8 314225.ELI_01530 1.586e-66 231.0 COG4960@1|root,COG4960@2|Bacteria,1RAYG@1224|Proteobacteria,2UJT9@28211|Alphaproteobacteria,2K6EK@204457|Sphingomonadales 204457|Sphingomonadales OU peptidase cpaA - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 PJD2_k127_936039_5 314225.ELI_01525 5.206e-136 442.0 COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,2K08W@204457|Sphingomonadales 204457|Sphingomonadales U Pilus assembly protein CpaB cpaB - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF PJD2_k127_936039_1 1122970.AUHC01000007_gene1707 4.785e-204 658.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,2K0ZQ@204457|Sphingomonadales 204457|Sphingomonadales U Belongs to the GSP D family cpaC - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N PJD2_k127_936039_7 237727.NAP1_00660 1.376e-76 262.0 COG5461@1|root,COG5461@2|Bacteria,1REYP@1224|Proteobacteria,2U8J3@28211|Alphaproteobacteria,2K5AY@204457|Sphingomonadales 204457|Sphingomonadales N Pilus assembly protein CpaD cpaD - - ko:K02281 - - - - ko00000,ko02035,ko02044 - - - Pilus_CpaD PJD2_k127_936039_0 314225.ELI_01510 3.909e-225 703.0 COG2204@1|root,COG4963@1|root,COG2204@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,2K0BT@204457|Sphingomonadales 204457|Sphingomonadales TU Flp pilus assembly protein, ATPase CpaE cpaE - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - CbiA,ParA PJD2_k127_936039_2 314225.ELI_01505 6.036e-158 503.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria,2K0B5@204457|Sphingomonadales 204457|Sphingomonadales U pilus assembly protein TadB - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF PJD2_k127_936039_3 314225.ELI_01500 6.436e-152 487.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2TSFA@28211|Alphaproteobacteria,2K03P@204457|Sphingomonadales 204457|Sphingomonadales NU type II secretion system protein - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF PJD2_k127_958421_5 1248760.ANFZ01000009_gene1524 2.399e-37 141.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria,2JZY1@204457|Sphingomonadales 204457|Sphingomonadales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS PJD2_k127_958421_1 1122970.AUHC01000009_gene281 1.499e-131 424.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria,2K1B1@204457|Sphingomonadales 204457|Sphingomonadales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase PJD2_k127_958421_3 161528.ED21_25347 2.544e-94 312.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2U5B2@28211|Alphaproteobacteria,2K00Z@204457|Sphingomonadales 204457|Sphingomonadales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF PJD2_k127_958421_2 161528.ED21_25352 1.451e-115 376.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,2K0JM@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf PJD2_k127_958421_4 279238.Saro_1374 1.436e-60 217.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2U9ED@28211|Alphaproteobacteria,2K1ET@204457|Sphingomonadales 204457|Sphingomonadales I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 PJD2_k127_958421_0 1144305.PMI02_00515 7.264e-172 558.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2TSD1@28211|Alphaproteobacteria,2K0YA@204457|Sphingomonadales 204457|Sphingomonadales I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom PJD2_k127_972700_0 1449076.JOOE01000004_gene382 2.481e-306 979.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TVIE@28211|Alphaproteobacteria,2K9PM@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec PJD2_k127_972700_3 1502850.FG91_00729 1.093e-211 668.0 COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,2TW2A@28211|Alphaproteobacteria,2K1A7@204457|Sphingomonadales 204457|Sphingomonadales G COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - - PJD2_k127_972700_7 13690.CP98_04670 2.238e-160 512.0 COG1680@1|root,COG1680@2|Bacteria,1MVR8@1224|Proteobacteria,2TVCD@28211|Alphaproteobacteria,2K2QS@204457|Sphingomonadales 204457|Sphingomonadales V Beta-lactamase - - - - - - - - - - - - Beta-lactamase PJD2_k127_972700_5 1449076.JOOE01000004_gene378 1.814e-173 561.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VD8E@28211|Alphaproteobacteria,2K2X2@204457|Sphingomonadales 204457|Sphingomonadales M D-Ala-D-Ala carboxypeptidase 3 (S13) family - - - - - - - - - - - - Peptidase_S13 PJD2_k127_972700_1 1112212.JH584235_gene302 2.254e-220 705.0 COG1228@1|root,COG4642@1|root,COG1228@2|Bacteria,COG4642@2|Bacteria,1MVAF@1224|Proteobacteria,2U4WG@28211|Alphaproteobacteria,2K1X8@204457|Sphingomonadales 204457|Sphingomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,CIA30 PJD2_k127_972700_2 1112212.JH584235_gene303 6.419e-218 688.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2K1RR@204457|Sphingomonadales 204457|Sphingomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 PJD2_k127_972700_12 1112214.AHIS01000095_gene817 6.63e-107 359.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,2TR16@28211|Alphaproteobacteria,2K34I@204457|Sphingomonadales 204457|Sphingomonadales M Mandelate racemase muconate lactonizing enzyme - - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N PJD2_k127_972700_9 1112212.JH584235_gene305 2.071e-158 507.0 COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2TS0Y@28211|Alphaproteobacteria,2K06Y@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N PJD2_k127_972700_10 1112212.JH584235_gene306 6.509e-140 449.0 COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2U1Y6@28211|Alphaproteobacteria,2K2S5@204457|Sphingomonadales 204457|Sphingomonadales K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate PJD2_k127_972700_8 1449076.JOOE01000004_gene372 4.661e-160 513.0 COG1680@1|root,COG1680@2|Bacteria,1RB35@1224|Proteobacteria,2U2A3@28211|Alphaproteobacteria,2K36P@204457|Sphingomonadales 204457|Sphingomonadales V Beta-lactamase - - - - - - - - - - - - Beta-lactamase PJD2_k127_972700_6 1112212.JH584235_gene3755 1.802e-164 526.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2K0PV@204457|Sphingomonadales 204457|Sphingomonadales C dehydratase - - - - - - - - - - - - CoA_transf_3 PJD2_k127_972700_11 1219035.NT2_01_06460 3.226e-113 377.0 COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,2TVBC@28211|Alphaproteobacteria,2K0JE@204457|Sphingomonadales 204457|Sphingomonadales I enoyl-CoA hydratase - - - - - - - - - - - - ECH_1,Flavin_Reduct PJD2_k127_972700_4 1174684.EBMC1_10279 4.347e-188 599.0 COG1960@1|root,COG1960@2|Bacteria,1MW0F@1224|Proteobacteria,2TR9I@28211|Alphaproteobacteria,2K12Q@204457|Sphingomonadales 204457|Sphingomonadales I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_972700_13 1219035.NT2_01_06430 5.566e-16 83.0 COG1960@1|root,COG1960@2|Bacteria,1NQAE@1224|Proteobacteria,2U0TJ@28211|Alphaproteobacteria,2K1RF@204457|Sphingomonadales 204457|Sphingomonadales I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N PJD2_k127_996859_3 1122970.AUHC01000001_gene422 5.157e-68 235.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2TR3W@28211|Alphaproteobacteria,2K02X@204457|Sphingomonadales 204457|Sphingomonadales F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase PJD2_k127_996859_4 627192.SLG_24120 9.493e-56 199.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2U7DJ@28211|Alphaproteobacteria,2K3W5@204457|Sphingomonadales 204457|Sphingomonadales S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY PJD2_k127_996859_2 314225.ELI_05675 3.839e-81 278.0 29EP3@1|root,301KZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_996859_0 1219035.NT2_06_02910 1.003e-263 825.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,2K0VR@204457|Sphingomonadales 204457|Sphingomonadales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Toprim_4,Toprim_N,zf-CHC2 PJD2_k127_996859_1 383381.EH30_05610 1.503e-98 328.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,2K260@204457|Sphingomonadales 204457|Sphingomonadales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 ## 1547 queries scanned ## Total time (seconds): 106.8569221496582 ## Rate: 14.48 q/s