## Wed Nov 13 08:09:09 2024 ## emapper-2.1.12 ## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/P/PJD2_bin.35.fa -m mmseqs --itype genome -o PJD2_bin.35 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/PJD2_bin.35 --cpu 28 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs PJD2_k127_1012186_0 926569.ANT_16170 2.507e-182 577.0 COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi 200795|Chloroflexi H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD PJD2_k127_1041195_1 398578.Daci_4877 1.87e-13 79.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4AAGH@80864|Comamonadaceae 28216|Betaproteobacteria NT chemotaxis - - - ko:K03406,ko:K03776,ko:K05874 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,PAS_3 PJD2_k127_1041195_3 768671.ThimaDRAFT_1046 8.913e-09 62.0 COG0226@1|root,COG0226@2|Bacteria,1N19C@1224|Proteobacteria,1SEQX@1236|Gammaproteobacteria,1WZ27@135613|Chromatiales 135613|Chromatiales P COG0226 ABC-type phosphate transport system, periplasmic component - - - - - - - - - - - - PBP_like_2 PJD2_k127_1041195_0 215803.DB30_6679 1.972e-18 93.0 2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria,439MQ@68525|delta/epsilon subdivisions,2X4YU@28221|Deltaproteobacteria,2YZV4@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_1041195_2 1056820.KB900700_gene1147 1.69e-11 79.0 COG2304@1|root,COG2304@2|Bacteria,1R7H7@1224|Proteobacteria,1SEG0@1236|Gammaproteobacteria,2PQ3H@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Zinc-dependent metalloprotease - - - - - - - - - - - - VWA,VWA_2 PJD2_k127_1067801_2 234267.Acid_1844 1.361e-47 177.0 COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria 57723|Acidobacteria S Mycothiol maleylpyruvate isomerase N-terminal domain - - - - - - - - - - - - DinB_2 PJD2_k127_1067801_0 56110.Oscil6304_1714 8.878e-188 594.0 COG0399@1|root,COG0399@2|Bacteria,1G4PM@1117|Cyanobacteria,1HFC1@1150|Oscillatoriales 1117|Cyanobacteria M PFAM DegT DnrJ EryC1 StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 PJD2_k127_1067801_1 1128427.KB904821_gene4640 7.461e-83 291.0 COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales 1117|Cyanobacteria E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 PJD2_k127_1099760_4 697329.Rumal_1773 5.816e-70 254.0 COG0204@1|root,COG0283@1|root,COG0204@2|Bacteria,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WIDU@541000|Ruminococcaceae 186801|Clostridia F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin PJD2_k127_1099760_2 448385.sce8915 1.742e-81 283.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2YUC9@29|Myxococcales 28221|Deltaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 PJD2_k127_1099760_5 641491.DND132_0439 1.374e-54 201.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,2M9YS@213115|Desulfovibrionales 28221|Deltaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.21,5.4.99.22 ko:K06178,ko:K06182 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 PJD2_k127_1099760_7 247490.KSU1_D0660 8.323e-41 162.0 COG1386@1|root,COG1386@2|Bacteria,2IZNB@203682|Planctomycetes 203682|Planctomycetes D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves - - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB PJD2_k127_1099760_8 1232410.KI421414_gene2895 1.494e-38 155.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales 28221|Deltaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA PJD2_k127_1099760_1 1191523.MROS_2554 6.128e-122 399.0 COG0180@1|root,COG0180@2|Bacteria 2|Bacteria J Tryptophanyl-tRNA synthetase trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b PJD2_k127_1099760_3 290397.Adeh_1687 1.12e-78 276.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2YWUR@29|Myxococcales 28221|Deltaproteobacteria D Phage integrase, N-terminal SAM-like domain xerD - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase PJD2_k127_1099760_9 1313304.CALK_0826 3.538e-06 56.0 COG0268@1|root,COG0268@2|Bacteria 2|Bacteria J rRNA binding rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p PJD2_k127_1099760_0 697303.Thewi_2280 2.667e-180 582.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,42FHT@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit PJD2_k127_1099760_6 1379698.RBG1_1C00001G1445 3.079e-49 185.0 COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria 2|Bacteria MU WD40-like Beta Propeller Repeat - - - ko:K03641,ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33,2.C.1.2 - - BSP,Bac_surface_Ag,PD40,Peptidase_MA_2 PJD2_k127_112077_1 1499967.BAYZ01000005_gene5436 8.604e-52 200.0 COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NQY2@2323|unclassified Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - DUF2723,PMT,PMT_2,TPR_19 PJD2_k127_112077_0 251229.Chro_5244 9.888e-68 236.0 COG0500@1|root,COG0500@2|Bacteria,1GIBJ@1117|Cyanobacteria,3VNFK@52604|Pleurocapsales 1117|Cyanobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 PJD2_k127_1134653_7 1519464.HY22_07810 2.215e-10 70.0 2CUTJ@1|root,32SW3@2|Bacteria,1FF20@1090|Chlorobi 1090|Chlorobi - - - - - - - - - - - - - - - PJD2_k127_1134653_4 945713.IALB_1059 1.14e-18 97.0 2EAWV@1|root,334Y2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_1134653_5 665959.HMPREF1013_03085 2.047e-13 83.0 COG3391@1|root,COG3391@2|Bacteria,1VCN6@1239|Firmicutes,4IQ7U@91061|Bacilli,1ZRHV@1386|Bacillus 91061|Bacilli S NHL repeat - - - - - - - - - - - - NHL PJD2_k127_1134653_2 1191523.MROS_2604 3.722e-78 296.0 COG5448@1|root,COG5448@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2460 PJD2_k127_1134653_3 1191523.MROS_0530 2.288e-32 145.0 COG4775@1|root,COG4775@2|Bacteria 2|Bacteria M membrane organization - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA PJD2_k127_1134653_0 1121468.AUBR01000045_gene1800 5.854e-260 810.0 COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,42FI5@68295|Thermoanaerobacterales 186801|Clostridia E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N PJD2_k127_1134653_1 1121468.AUBR01000045_gene1802 9.064e-123 407.0 COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales 186801|Clostridia F Belongs to the metallo-dependent hydrolases superfamily. HutI family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 PJD2_k127_1134653_6 1379270.AUXF01000006_gene26 8.271e-12 77.0 COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_8 PJD2_k127_1151552_1 452637.Oter_3891 3.711e-156 504.0 COG3007@1|root,COG3007@2|Bacteria,46S92@74201|Verrucomicrobia,3K7W2@414999|Opitutae 414999|Opitutae I Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) fabV - 1.3.1.44,1.3.1.9 ko:K00209 ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212 M00083 R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase PJD2_k127_1151552_2 485913.Krac_1006 4.831e-97 334.0 COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi 200795|Chloroflexi EGP PFAM major facilitator superfamily MFS_1 - - - ko:K08162 - - - - ko00000,ko02000 2.A.1.2.21 - - MFS_1,MFS_1_like,Sugar_tr PJD2_k127_1151552_4 401526.TcarDRAFT_1878 2.508e-88 304.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H28V@909932|Negativicutes 909932|Negativicutes F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase PJD2_k127_1151552_0 1304888.ATWF01000001_gene955 0.0 1138.0 COG0458@1|root,COG0458@2|Bacteria,2GEX8@200930|Deferribacteres 200930|Deferribacteres F Carbamoyl-phosphate synthetase large chain, oligomerisation domain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS PJD2_k127_1151552_5 335543.Sfum_0374 3.364e-48 185.0 COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MRJB@213462|Syntrophobacterales 28221|Deltaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 PJD2_k127_1151552_3 1121456.ATVA01000011_gene1845 1.214e-89 321.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2M7XJ@213115|Desulfovibrionales 28221|Deltaproteobacteria E extracellular solute-binding protein, family 5 - - - ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 PJD2_k127_1151552_6 644282.Deba_0969 3.252e-24 105.0 COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N PJD2_k127_1156258_13 172088.AUGA01000012_gene7136 2.673e-27 113.0 2EGBE@1|root,33A39@2|Bacteria,1N3MX@1224|Proteobacteria,2UE26@28211|Alphaproteobacteria,3K0D7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_1156258_4 861299.J421_0692 1.191e-98 331.0 COG0262@1|root,COG0262@2|Bacteria 2|Bacteria H dihydrofolate reductase activity - - - - - - - - - - - - RibD_C PJD2_k127_1156258_6 748247.AZKH_4441 5.116e-63 224.0 COG3189@1|root,COG3189@2|Bacteria,1RHYB@1224|Proteobacteria,2VSIB@28216|Betaproteobacteria,2KYQ7@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 PJD2_k127_1156258_0 1123073.KB899243_gene698 9.207e-204 643.0 COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQRJ@1236|Gammaproteobacteria,1X83S@135614|Xanthomonadales 135614|Xanthomonadales E Pyridoxal-dependent decarboxylase conserved domain - - - - - - - - - - - - Pyridoxal_deC PJD2_k127_1156258_5 765912.Thimo_0714 9.474e-80 291.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1WWYK@135613|Chromatiales 135613|Chromatiales P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA PJD2_k127_1156258_2 1415778.JQMM01000001_gene208 1.378e-147 475.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1J5UZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex PJD2_k127_1156258_3 1211579.PP4_10730 1.404e-132 439.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 PJD2_k127_1156258_8 754476.Q7A_1961 2.388e-52 194.0 COG1075@1|root,COG1075@2|Bacteria,1QY7X@1224|Proteobacteria,1SBPW@1236|Gammaproteobacteria 1236|Gammaproteobacteria K PGAP1-like protein - - - - - - - - - - - - DUF676,PGAP1 PJD2_k127_1156258_1 330214.NIDE0014 1.759e-153 492.0 COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria 2|Bacteria P nitrite reductase [NAD(P)H] activity - - 1.2.3.3,1.6.5.2,1.7.1.15 ko:K00158,ko:K00363,ko:K03809,ko:K05710 ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220 M00530,M00545 R00207,R00787,R02964,R03643,R03816,R06782,R06783 RC00098,RC00176,RC00819,RC02745 br01602,ko00000,ko00001,ko00002,ko01000 - - - FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N PJD2_k127_1156258_15 1484460.JSWG01000007_gene3140 6.376e-12 71.0 2DZVD@1|root,32VJZ@2|Bacteria,4NUB2@976|Bacteroidetes,1I482@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - ydhR PJD2_k127_1156258_9 1279009.ADICEAN_02819 5.226e-49 178.0 COG0454@1|root,COG0456@2|Bacteria,4NPGI@976|Bacteroidetes,47R57@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain yjaB - - ko:K03827 - - - - ko00000,ko01000 - - - Acetyltransf_10 PJD2_k127_1156258_10 653733.Selin_0267 9.984e-45 167.0 COG2076@1|root,COG2076@2|Bacteria 2|Bacteria P Multidrug Resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res PJD2_k127_1156258_7 391625.PPSIR1_30385 2.994e-53 195.0 COG1670@1|root,COG1670@2|Bacteria,1RKKE@1224|Proteobacteria,43APS@68525|delta/epsilon subdivisions,2X63H@28221|Deltaproteobacteria,2YVYC@29|Myxococcales 28221|Deltaproteobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 PJD2_k127_1156258_11 1198114.AciX9_3506 2.079e-42 165.0 COG3797@1|root,COG3797@2|Bacteria,3Y5RN@57723|Acidobacteria,2JJWX@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function (DUF1697) - - - - - - - - - - - - DUF1697 PJD2_k127_1156258_14 926560.KE387023_gene2058 3.504e-24 108.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT PJD2_k127_1156258_12 1121405.dsmv_1388 5.085e-38 145.0 2APA5@1|root,31EC7@2|Bacteria,1RHMQ@1224|Proteobacteria,42UND@68525|delta/epsilon subdivisions,2WQK4@28221|Deltaproteobacteria,2MM23@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_1176900_9 1125863.JAFN01000001_gene3034 7.654e-40 171.0 COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria 28221|Deltaproteobacteria T metal-dependent phosphohydrolase HD region - - - - - - - - - - - - GAF_2,GAF_3,HD,Response_reg PJD2_k127_1176900_7 443143.GM18_0237 7.749e-48 198.0 COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria,43UI6@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF_2,HATPase_c,HisKA PJD2_k127_1176900_11 861299.J421_5622 2.039e-23 111.0 COG0642@1|root,COG2205@2|Bacteria 861299.J421_5622|- T PhoQ Sensor - - - - - - - - - - - - - PJD2_k127_1176900_6 697303.Thewi_1663 1.821e-75 269.0 COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,42FF0@68295|Thermoanaerobacterales 186801|Clostridia T Response regulator receiver - - - - - - - - - - - - GGDEF,Response_reg PJD2_k127_1176900_4 553973.CLOHYLEM_07748 5.141e-89 305.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,21XEQ@1506553|Lachnoclostridium 186801|Clostridia O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 PJD2_k127_1176900_8 1335757.SPICUR_02025 5.066e-46 168.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1WYPR@135613|Chromatiales 135613|Chromatiales K Belongs to the P(II) protein family - - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II PJD2_k127_1176900_5 1134445.AJJM01000010_gene3042 6.343e-83 309.0 COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria 201174|Actinobacteria OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE PJD2_k127_1176900_1 1499967.BAYZ01000102_gene3561 3.989e-137 474.0 COG4262@1|root,COG4262@2|Bacteria,2NS3W@2323|unclassified Bacteria 2|Bacteria S Spermine/spermidine synthase domain - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - MFS_1,Spermine_synth PJD2_k127_1176900_2 243231.GSU1820 6.704e-113 402.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales 28221|Deltaproteobacteria H Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2 PJD2_k127_1176900_0 667014.Thein_2196 2.255e-227 713.0 COG0174@1|root,COG0174@2|Bacteria,2GH5N@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N PJD2_k127_1176900_3 635013.TherJR_0655 6.315e-108 368.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae 186801|Clostridia H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - ACPS,Carb_kinase,YjeF_N PJD2_k127_1176900_10 342949.PNA2_0246 9.682e-28 123.0 COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,243KR@183968|Thermococci 183968|Thermococci S Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro - - - ko:K07025 - - - - ko00000 - - - HAD_2 PJD2_k127_1176900_14 1042163.BRLA_c000440 3.813e-09 67.0 COG1266@1|root,COG1266@2|Bacteria,1V4WD@1239|Firmicutes,4HM94@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi PJD2_k127_1176900_12 861299.J421_3007 1.5e-21 98.0 2EQ8R@1|root,33HV0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_1176900_13 309798.COPRO5265_1458 4.899e-11 75.0 2DTCK@1|root,33JQD@2|Bacteria,1VNW3@1239|Firmicutes,24X19@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - PJD2_k127_1176900_15 400682.PAC_15701018 3.202e-08 65.0 KOG2177@1|root,KOG2177@2759|Eukaryota 2759|Eukaryota O zinc ion binding TRIM64 - 2.3.2.27 ko:K10650,ko:K10651,ko:K12019,ko:K12038 ko05322,map05322 - - - ko00000,ko00001,ko01000,ko03019,ko04121,ko04131 - - - PRY,SPRY,zf-B_box,zf-C3HC4,zf-C3HC4_4 PJD2_k127_1185107_3 1121456.ATVA01000012_gene2805 5.459e-63 228.0 COG0438@1|root,COG0535@1|root,COG0438@2|Bacteria,COG0535@2|Bacteria,1NB81@1224|Proteobacteria,42WA6@68525|delta/epsilon subdivisions,2WRYV@28221|Deltaproteobacteria,2MD0F@213115|Desulfovibrionales 28221|Deltaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,SPASM PJD2_k127_1185107_1 573.JG24_03400 7.441e-78 285.0 COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,1S0BA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M glycosyl transferase group 1 - - 2.4.1.56 ko:K03280 ko00540,ko01100,map00540,map01100 M00080 R01996 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT4,GT9 - Glyco_transf_4,Glycos_transf_1 PJD2_k127_1185107_2 1121456.ATVA01000012_gene2804 4.581e-69 260.0 COG0438@1|root,COG0438@2|Bacteria,1MUYN@1224|Proteobacteria,43F2S@68525|delta/epsilon subdivisions,2X35V@28221|Deltaproteobacteria,2ME5E@213115|Desulfovibrionales 28221|Deltaproteobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 PJD2_k127_1185107_4 1123284.KB899043_gene413 1.65e-10 64.0 2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - PJD2_k127_1185107_5 272635.MYPU_1060 1.963e-10 70.0 COG2890@1|root,COG2890@2|Bacteria,3WTXX@544448|Tenericutes 544448|Tenericutes J Belongs to the protein N5-glutamine methyltransferase family hemK - 2.1.1.297,2.7.7.87 ko:K02493,ko:K07566 - - R10463,R10806 RC00003,RC00745,RC03279 ko00000,ko01000,ko03009,ko03012,ko03016 - - - MTS,Methyltransf_31 PJD2_k127_1185107_0 243090.RB8598 9.008e-234 744.0 COG0243@1|root,COG0243@2|Bacteria,2IXVV@203682|Planctomycetes 203682|Planctomycetes C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding PJD2_k127_1200969_1 1096546.WYO_2487 2.932e-07 63.0 COG0683@1|root,COG0683@2|Bacteria,1N3V5@1224|Proteobacteria,2U1KS@28211|Alphaproteobacteria,1JUFA@119045|Methylobacteriaceae 28211|Alphaproteobacteria E PFAM Extracellular ligand-binding receptor - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 PJD2_k127_1200969_2 1121923.GPUN_0445 5.263e-07 59.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria,464BN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C PJD2_k127_1200969_0 1089553.Tph_c25520 2.064e-12 78.0 COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,42EQV@68295|Thermoanaerobacterales 186801|Clostridia M PFAM cell wall hydrolase autolysin cwlD - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 PJD2_k127_1218483_0 251229.Chro_2918 1.898e-158 507.0 COG0436@1|root,COG0436@2|Bacteria,1GHX7@1117|Cyanobacteria,3VM7E@52604|Pleurocapsales 1117|Cyanobacteria E PFAM Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 PJD2_k127_1218483_2 1499967.BAYZ01000137_gene104 9.252e-94 317.0 COG0549@1|root,COG0549@2|Bacteria,2NNKM@2323|unclassified Bacteria 2|Bacteria E Amino acid kinase family arcC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452 AA_kinase PJD2_k127_1218483_4 913865.DOT_2528 1.165e-58 224.0 COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,261WJ@186807|Peptococcaceae 186801|Clostridia S conserved protein (DUF2088) - - - - - - - - - - - - DUF2088 PJD2_k127_1218483_1 546271.Selsp_1021 1.55e-128 443.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes 909932|Negativicutes F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N PJD2_k127_1218483_5 525904.Tter_1405 3.969e-35 153.0 COG0041@1|root,COG0041@2|Bacteria,2NPN4@2323|unclassified Bacteria 2|Bacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_0575,iJN678.purE,iJN746.PP_5336,iNJ661.Rv3275c,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 AIRC PJD2_k127_1218483_8 945713.IALB_0763 2.892e-21 103.0 COG0009@1|root,COG0009@2|Bacteria 2|Bacteria J L-threonylcarbamoyladenylate synthase tsaC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.5.2.3 ko:K01465,ko:K07479,ko:K07566 ko00240,ko01100,map00240,map01100 M00051 R01993,R10463 RC00632,RC00745 ko00000,ko00001,ko00002,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC PJD2_k127_1218483_7 456320.Mvol_0239 7.128e-24 118.0 COG0535@1|root,arCOG00938@2157|Archaea,2Y12G@28890|Euryarchaeota,23R8Z@183939|Methanococci 183939|Methanococci S Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM PJD2_k127_1218483_3 1499967.BAYZ01000089_gene5013 1.535e-77 276.0 COG1519@1|root,COG1519@2|Bacteria,2NP5A@2323|unclassified Bacteria 2|Bacteria M 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) waaA GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527,ko:K03439 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03016 - GT30 - Glycos_transf_N PJD2_k127_1218483_6 1499967.BAYZ01000119_gene3208 7.153e-33 141.0 COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase, family 9 - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 PJD2_k127_1218483_9 877415.JNJQ01000002_gene2369 2.284e-20 98.0 COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,3VQIC@526524|Erysipelotrichia 526524|Erysipelotrichia K Cupin domain protein - - - - - - - - - - - - Cupin_2,HTH_19,HTH_3 PJD2_k127_1218483_11 1200792.AKYF01000020_gene5161 5.198e-13 76.0 COG1396@1|root,COG3837@1|root,COG1396@2|Bacteria,COG3837@2|Bacteria,1V22T@1239|Firmicutes,4HFPB@91061|Bacilli 91061|Bacilli K Cupin domain - - - - - - - - - - - - Cupin_2,HTH_3 PJD2_k127_1218483_10 1379698.RBG1_1C00001G0404 3.279e-15 80.0 2EAFJ@1|root,334IY@2|Bacteria,2NRZR@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF1844) - - - - - - - - - - - - DUF1844 PJD2_k127_1221620_14 1242864.D187_002029 1.051e-26 111.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 PJD2_k127_1221620_15 1041826.FCOL_00125 2.293e-20 96.0 COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1I32F@117743|Flavobacteriia,2NU90@237|Flavobacterium 976|Bacteroidetes C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 PJD2_k127_1221620_3 118005.AWNK01000006_gene1206 6.986e-119 398.0 COG1005@1|root,COG1005@2|Bacteria 2|Bacteria C quinone binding nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh PJD2_k127_1221620_5 945713.IALB_0893 2.518e-107 377.0 COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria 2|Bacteria C formate dehydrogenase (NAD+) activity nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 PJD2_k127_1221620_0 653733.Selin_0886 6.338e-168 539.0 COG1894@1|root,COG1894@2|Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00334,ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB PJD2_k127_1221620_10 760154.Sulba_0412 5.836e-52 189.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SRI@68525|delta/epsilon subdivisions,2YQ7X@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria C NADH-quinone oxidoreductase nuoE - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx PJD2_k127_1221620_1 653733.Selin_0888 1.335e-150 488.0 COG0649@1|root,COG0649@2|Bacteria 2|Bacteria C NAD binding nuoD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa PJD2_k127_1221620_12 247490.KSU1_D0327 3.844e-32 132.0 COG0852@1|root,COG0852@2|Bacteria,2IZCK@203682|Planctomycetes 203682|Planctomycetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa PJD2_k127_1221620_7 1244531.CIG1485E_0172 1.308e-69 247.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2YMUT@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 PJD2_k127_1221620_11 237368.SCABRO_03987 8.604e-42 162.0 COG3222@1|root,COG3222@2|Bacteria,2J0B9@203682|Planctomycetes 203682|Planctomycetes S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 PJD2_k127_1221620_8 1379698.RBG1_1C00001G0457 1.118e-66 235.0 COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria 2|Bacteria S (Rhomboid) family GlpG - - ko:K07059 - - - - ko00000 - - - Rhomboid PJD2_k127_1221620_13 477974.Daud_1067 3.914e-31 131.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia,261XP@186807|Peptococcaceae 186801|Clostridia G Belongs to the phosphoglycerate mutase family pspA - 3.1.3.3,3.1.3.73 ko:K02226,ko:K22305 ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130 M00122 R00582,R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 PJD2_k127_1221620_2 1502850.FG91_00925 4.125e-142 463.0 COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PR9I@1224|Proteobacteria,2U1SM@28211|Alphaproteobacteria,2K253@204457|Sphingomonadales 204457|Sphingomonadales C 4Fe-4S binding domain - - - - - - - - - - - - Fer4,Fer4_4,Pyr_redox_3 PJD2_k127_1221620_9 945713.IALB_0798 5.77e-54 200.0 COG0492@1|root,COG0492@2|Bacteria 2|Bacteria C ferredoxin-NADP+ reductase activity - - - - - - - - - - - - FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding PJD2_k127_1221620_4 880073.Calab_3334 4.817e-116 398.0 COG0484@1|root,COG0484@2|Bacteria 2|Bacteria O heat shock protein binding - - - - - - - - - - - - Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7 PJD2_k127_1221620_6 1408473.JHXO01000005_gene1865 9.703e-77 276.0 COG0484@1|root,COG0484@2|Bacteria,4NPS0@976|Bacteroidetes,2FXKU@200643|Bacteroidia 976|Bacteroidetes O heat shock protein binding - - - - - - - - - - - - - PJD2_k127_125073_16 523794.Lebu_0561 9.277e-05 45.0 COG0525@1|root,COG0525@2|Bacteria,378RD@32066|Fusobacteria 32066|Fusobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 PJD2_k127_125073_13 1125701.HMPREF1221_00698 7.601e-10 66.0 COG1426@1|root,COG1426@2|Bacteria,2J61E@203691|Spirochaetes 203691|Spirochaetes S Helix-turn-helix domain - - - - - - - - - - - - HTH_25 PJD2_k127_125073_0 880073.Calab_3212 1.012e-273 856.0 COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria 2|Bacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB PJD2_k127_125073_6 502025.Hoch_6033 2.276e-58 215.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,2YUYQ@29|Myxococcales 28221|Deltaproteobacteria H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1988 QRPTase_C,QRPTase_N PJD2_k127_125073_8 1121346.KB899818_gene2590 1.327e-39 161.0 COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae 91061|Bacilli K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 PJD2_k127_125073_12 314230.DSM3645_11592 2.294e-18 98.0 COG1521@1|root,COG1521@2|Bacteria,2J0M0@203682|Planctomycetes 203682|Planctomycetes F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase PJD2_k127_125073_9 596151.DesfrDRAFT_2907 1.252e-31 126.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MCH7@213115|Desulfovibrionales 28221|Deltaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 PJD2_k127_125073_1 671143.DAMO_2457 2.067e-238 747.0 COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria 2|Bacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 PJD2_k127_125073_11 477974.Daud_0096 1.529e-20 96.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,24MN5@186801|Clostridia,262W6@186807|Peptococcaceae 186801|Clostridia H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB PJD2_k127_125073_10 1382356.JQMP01000003_gene1502 8.855e-30 124.0 COG0801@1|root,COG0801@2|Bacteria,2G6YT@200795|Chloroflexi,27YCY@189775|Thermomicrobia 189775|Thermomicrobia H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) - - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK PJD2_k127_125073_5 671143.DAMO_2311 1.608e-58 216.0 COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria 2|Bacteria F Deoxynucleoside kinase dgk - 2.7.1.113 ko:K15518 ko00230,map00230 - R01967 RC00002,RC00017 ko00000,ko00001,ko01000 - - - HPPK,dNK PJD2_k127_125073_2 269799.Gmet_1642 5.197e-96 329.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,43S2A@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf PJD2_k127_125073_3 1121430.JMLG01000002_gene1142 9.978e-79 274.0 COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,26011@186807|Peptococcaceae 186801|Clostridia H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase PJD2_k127_125073_4 484770.UFO1_4299 1.166e-66 237.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H30V@909932|Negativicutes 909932|Negativicutes M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase PJD2_k127_125073_7 760568.Desku_2804 5.552e-47 184.0 COG0537@1|root,COG0537@2|Bacteria,1V5CH@1239|Firmicutes,24HFR@186801|Clostridia,266WR@186807|Peptococcaceae 186801|Clostridia FG Scavenger mRNA decapping enzyme C-term binding - - 2.7.7.53 ko:K19710 ko00230,map00230 - R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 - - - HIT PJD2_k127_125073_15 1307761.L21SP2_1443 5.049e-08 61.0 COG1316@1|root,COG1316@2|Bacteria,2J57I@203691|Spirochaetes 203691|Spirochaetes K PFAM Cell envelope-related transcriptional attenuator domain - - - - - - - - - - - - LytR_C,LytR_cpsA_psr PJD2_k127_125073_14 649638.Trad_1936 7.267e-09 59.0 COG1826@1|root,COG1826@2|Bacteria,1WKJH@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 PJD2_k127_1259344_9 211114.JOEF01000004_gene6463 3.234e-17 83.0 COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4E5WK@85010|Pseudonocardiales 201174|Actinobacteria P Rieske-like [2Fe-2S] domain - - - ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske PJD2_k127_1259344_1 314230.DSM3645_07186 1.659e-169 543.0 COG1282@1|root,COG1282@2|Bacteria,2IYIA@203682|Planctomycetes 203682|Planctomycetes C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB PJD2_k127_1259344_6 1191523.MROS_2381 1.044e-34 135.0 COG3288@1|root,COG3288@2|Bacteria 2|Bacteria C NAD(P)+ transhydrogenase (AB-specific) activity pntA-2 - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM PJD2_k127_1259344_2 1382359.JIAL01000001_gene94 1.132e-142 463.0 COG3288@1|root,COG3288@2|Bacteria,3Y2S0@57723|Acidobacteria,2JM52@204432|Acidobacteriia 204432|Acidobacteriia C Alanine dehydrogenase/PNT, N-terminal domain - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N PJD2_k127_1259344_10 1379698.RBG1_1C00001G0428 3.112e-16 93.0 COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NREM@2323|unclassified Bacteria 2|Bacteria O Evidence 5 No homology to any previously reported sequences - - - ko:K20952 ko05111,map05111 - - - ko00000,ko00001 - - - B_lectin,FlgD_ig,PQQ_2,PQQ_3,Pkinase,VCBS PJD2_k127_1259344_5 1392490.JHZX01000001_gene628 7.574e-79 291.0 COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,1I1YW@117743|Flavobacteriia 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - PKD,UnbV_ASPIC,VCBS PJD2_k127_1259344_4 1121448.DGI_0529 1.444e-79 278.0 COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria,2MF83@213115|Desulfovibrionales 28221|Deltaproteobacteria S NHL repeat - - - - - - - - - - - - NHL PJD2_k127_1259344_0 502025.Hoch_5291 4.783e-256 797.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2YU8H@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh PJD2_k127_1259344_3 643648.Slip_1701 2.318e-110 369.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,42JRJ@68298|Syntrophomonadaceae 186801|Clostridia G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C PJD2_k127_1259344_8 646529.Desaci_2923 5.008e-18 85.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae 186801|Clostridia G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C PJD2_k127_1259344_7 926560.KE387023_gene2058 2.266e-23 101.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT PJD2_k127_127142_3 1123400.KB904747_gene519 4.658e-26 115.0 COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,1RS0P@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA PJD2_k127_127142_0 1095769.CAHF01000010_gene1238 1.675e-117 391.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,472GS@75682|Oxalobacteraceae 28216|Betaproteobacteria F DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C PJD2_k127_127142_5 926550.CLDAP_06890 5.704e-14 80.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity ste14 - - - - - - - - - - - ICMT,PEMT PJD2_k127_127142_1 331869.BAL199_24289 1.511e-50 192.0 COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VC8M@28211|Alphaproteobacteria,4BSKF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria H Acetyltransferase (GNAT) family - - - - - - - - - - - - - PJD2_k127_127142_4 450851.PHZ_c3183 8.366e-26 111.0 COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2UDEK@28211|Alphaproteobacteria,2KGZA@204458|Caulobacterales 204458|Caulobacterales S PFAM Membrane protein of - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 PJD2_k127_127142_2 869213.JCM21142_72957 1.055e-42 160.0 2A42S@1|root,30SMP@2|Bacteria,4P40W@976|Bacteroidetes 976|Bacteroidetes S Nickel-containing superoxide dismutase - - - - - - - - - - - - Sod_Ni PJD2_k127_1300223_5 314278.NB231_04685 5.461e-152 490.0 COG1453@1|root,COG1453@2|Bacteria,1NIR6@1224|Proteobacteria,1T3EJ@1236|Gammaproteobacteria,1X2PW@135613|Chromatiales 135613|Chromatiales S 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_22 PJD2_k127_1300223_13 446470.Snas_3652 3.417e-20 98.0 COG0664@1|root,COG0664@2|Bacteria,2IRJW@201174|Actinobacteria 201174|Actinobacteria T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - cNMP_binding PJD2_k127_1300223_8 518766.Rmar_2588 4.514e-105 348.0 COG0543@1|root,COG0543@2|Bacteria 2|Bacteria C 2 iron, 2 sulfur cluster binding asrB - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 PJD2_k127_1300223_7 272134.KB731324_gene5863 1.157e-121 394.0 COG1941@1|root,COG1941@2|Bacteria 2|Bacteria C coenzyme F420 hydrogenase activity hoxY - - - - - - - - - - - Oxidored_q6 PJD2_k127_1300223_4 247490.KSU1_A0077 9.987e-191 605.0 COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes 203682|Planctomycetes C Nickel-dependent hydrogenase - - - - - - - - - - - - NiFeSe_Hases PJD2_k127_1300223_12 622637.KE124774_gene1613 5.263e-25 121.0 COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,2UIK4@28211|Alphaproteobacteria,370CV@31993|Methylocystaceae 28211|Alphaproteobacteria C Hydrogenase maturation protease - - - - - - - - - - - - HycI PJD2_k127_1300223_2 251229.Chro_4403 3.167e-246 787.0 COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,3VI6E@52604|Pleurocapsales 1117|Cyanobacteria O PFAM HypF finger hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF PJD2_k127_1300223_6 518766.Rmar_2596 2.628e-138 452.0 COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes 976|Bacteroidetes O TIGRFAM hydrogenase expression formation protein HypE - - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C PJD2_k127_1300223_0 519989.ECTPHS_12545 0.0 1128.0 COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1WWWU@135613|Chromatiales 135613|Chromatiales C CoA-binding domain protein - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig PJD2_k127_1300223_3 194439.CT1834 1.662e-204 645.0 COG0372@1|root,COG0372@2|Bacteria,1FD5Z@1090|Chlorobi 1090|Chlorobi H Belongs to the citrate synthase family - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt PJD2_k127_1300223_1 485915.Dret_1750 3.379e-268 848.0 COG0021@1|root,COG0021@2|Bacteria 2|Bacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_N,XFP,XFP_N PJD2_k127_1300223_11 1267535.KB906767_gene4838 9.569e-48 189.0 COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 PJD2_k127_1300223_10 1047013.AQSP01000123_gene1525 3.967e-55 212.0 COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria 2|Bacteria T Tetratricopeptide repeat - - - - - - - - - - - - Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 PJD2_k127_1300223_9 1379698.RBG1_1C00001G0520 2.197e-73 265.0 COG2208@1|root,COG2208@2|Bacteria 2|Bacteria T phosphoserine phosphatase activity rsbU - 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 - - - CHASE2,GAF,GAF_2,HATPase_c_2,SpoIIE PJD2_k127_1306916_6 118168.MC7420_8337 2.517e-07 62.0 COG0457@1|root,COG0457@2|Bacteria,1G5S0@1117|Cyanobacteria,1HC37@1150|Oscillatoriales 1117|Cyanobacteria S K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - - PJD2_k127_1306916_1 1499967.BAYZ01000088_gene5087 7.158e-109 368.0 COG0621@1|root,COG0621@2|Bacteria,2NP2U@2323|unclassified Bacteria 2|Bacteria J Uncharacterized protein family UPF0004 yqeV GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 PJD2_k127_1306916_2 330214.NIDE3489 2.516e-100 339.0 COG4243@1|root,COG4243@2|Bacteria 2|Bacteria S quinone binding - - 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - - PJD2_k127_1306916_4 459349.CLOAM0442 3.015e-34 155.0 COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3 PJD2_k127_1306916_5 357808.RoseRS_3008 2.522e-17 99.0 COG0739@1|root,COG2304@1|root,COG4412@1|root,COG0739@2|Bacteria,COG2304@2|Bacteria,COG4412@2|Bacteria,2GB3W@200795|Chloroflexi,377V9@32061|Chloroflexia 32061|Chloroflexia E PFAM von Willebrand factor type A - - 3.4.21.50 ko:K01337 - - - - ko00000,ko01000,ko01002 - - - VWA PJD2_k127_1306916_0 760568.Desku_2105 5.138e-119 436.0 COG1404@1|root,COG3934@1|root,COG4733@1|root,COG1404@2|Bacteria,COG3934@2|Bacteria,COG4733@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,260VW@186807|Peptococcaceae 186801|Clostridia O Belongs to the peptidase S8 family - - 3.4.21.66 ko:K08651,ko:K13274,ko:K13276,ko:K13277 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 PJD2_k127_1306916_3 880073.Calab_3776 1.218e-72 250.0 COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 PJD2_k127_1307686_2 1209989.TepiRe1_2340 3.907e-142 477.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,42F0R@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g PJD2_k127_1307686_8 1379698.RBG1_1C00001G0842 1.618e-72 258.0 COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria 2|Bacteria M Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N PJD2_k127_1307686_4 1236959.BAMT01000004_gene774 1.198e-126 425.0 COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,2VH92@28216|Betaproteobacteria,2KKT8@206350|Nitrosomonadales 206350|Nitrosomonadales P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system cysA - 3.6.3.25 ko:K02045 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.1,3.A.1.6.3 - - ABC_tran,TOBE_3 PJD2_k127_1307686_7 153948.NAL212_2090 1.156e-122 399.0 COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,3729U@32003|Nitrosomonadales 28216|Betaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component cysW - - ko:K02047 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - - BPD_transp_1 PJD2_k127_1307686_6 251221.35212640 6.324e-125 415.0 COG0555@1|root,COG0555@2|Bacteria,1FZVV@1117|Cyanobacteria 1117|Cyanobacteria O Sulfate ABC transporter, permease protein CysT - - - ko:K02046 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - - BPD_transp_1 PJD2_k127_1307686_15 1132855.KB913035_gene2606 6.195e-10 72.0 COG3746@1|root,COG3746@2|Bacteria,1RAJS@1224|Proteobacteria,2W82Y@28216|Betaproteobacteria,2KNJJ@206350|Nitrosomonadales 206350|Nitrosomonadales P Phosphate-selective porin O and P - - - - - - - - - - - - Porin_O_P PJD2_k127_1307686_1 85643.Tmz1t_0628 5.578e-150 490.0 COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,2KV40@206389|Rhodocyclales 206389|Rhodocyclales P COG1613 ABC-type sulfate transport system, periplasmic component - - - ko:K02048 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - - SBP_bac_11 PJD2_k127_1307686_0 765912.Thimo_0377 8.052e-156 507.0 COG2203@1|root,COG2204@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1X2UX@135613|Chromatiales 135613|Chromatiales T Sigma-54 interaction domain - - - - - - - - - - - - Sigma54_activat PJD2_k127_1307686_13 929556.Solca_1759 5.308e-24 105.0 2EM7W@1|root,33EX0@2|Bacteria,4P5SH@976|Bacteroidetes,1J02V@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - PJD2_k127_1307686_5 313606.M23134_01996 2.41e-125 423.0 COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,47M0X@768503|Cytophagia 976|Bacteroidetes EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 PJD2_k127_1307686_3 498761.HM1_1355 2.328e-139 458.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia 186801|Clostridia J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c PJD2_k127_1307686_9 1157634.KB912975_gene575 1.003e-56 213.0 COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria 201174|Actinobacteria G COG2513 PEP phosphonomutase and related enzymes - - - - - - - - - - - - PEP_mutase PJD2_k127_1307686_10 400668.Mmwyl1_0968 1.594e-45 170.0 COG0454@1|root,COG0454@2|Bacteria,1QWFR@1224|Proteobacteria,1S6VC@1236|Gammaproteobacteria,1XKW5@135619|Oceanospirillales 135619|Oceanospirillales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 PJD2_k127_1307686_11 96561.Dole_1666 2.613e-45 171.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria,2MJZP@213118|Desulfobacterales 28221|Deltaproteobacteria I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB PJD2_k127_1307686_12 1123388.AQWU01000027_gene312 1.636e-36 153.0 COG1211@1|root,COG1211@2|Bacteria,1WI23@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD PJD2_k127_1307686_14 1218103.CIN01S_17_01120 1.64e-12 74.0 COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia,3ZQ15@59732|Chryseobacterium 976|Bacteroidetes Q Mammalian cell entry protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD PJD2_k127_1315735_8 1047013.AQSP01000088_gene1631 3.329e-21 104.0 COG1629@1|root,COG1629@2|Bacteria,2NS4U@2323|unclassified Bacteria 2|Bacteria P PFAM TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec PJD2_k127_1315735_9 459349.CLOAM0631 1.586e-20 106.0 COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3 PJD2_k127_1315735_4 1134912.AJTV01000030_gene2088 4.465e-90 317.0 COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,1MYCW@1224|Proteobacteria 1224|Proteobacteria Q Belongs to the peptidase S8 family - - - - - - - - - - - - PA PJD2_k127_1315735_1 1123508.JH636443_gene4951 9.54e-166 530.0 COG0006@1|root,COG0006@2|Bacteria,2IXJI@203682|Planctomycetes 203682|Planctomycetes E PFAM peptidase M24 - - - - - - - - - - - - Peptidase_M24 PJD2_k127_1315735_0 1237149.C900_05170 1.447e-249 782.0 COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47MDS@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran,Peptidase_C39 PJD2_k127_1315735_6 324602.Caur_1277 2.788e-43 164.0 2E65M@1|root,330UB@2|Bacteria,2G8DC@200795|Chloroflexi 200795|Chloroflexi S DinB superfamily - - - - - - - - - - - - DinB_2 PJD2_k127_1315735_7 483219.LILAB_31345 3.542e-31 125.0 COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales 28221|Deltaproteobacteria L Smr domain - - - - - - - - - - - - Smr PJD2_k127_1315735_3 929713.NIASO_05185 1.96e-127 414.0 COG2513@1|root,COG2513@2|Bacteria,4NMEH@976|Bacteroidetes 976|Bacteroidetes G Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - PEP_mutase PJD2_k127_1315735_5 861299.J421_0340 2.632e-70 249.0 COG3595@1|root,COG3595@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4097,PA14 PJD2_k127_1315735_10 523791.Kkor_0488 5.899e-14 82.0 COG3595@1|root,COG3595@2|Bacteria,1NG89@1224|Proteobacteria,1SCZV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF4097 PJD2_k127_1315735_2 1499967.BAYZ01000155_gene629 6.009e-149 486.0 COG0116@1|root,COG0116@2|Bacteria 2|Bacteria L 23S rRNA (guanine(2445)-N(2))-methyltransferase activity rlmL GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 ko:K07444,ko:K12297 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Methyltrans_SAM,THUMP,UPF0020 PJD2_k127_1315735_13 220668.lp_3218 0.0001143 54.0 COG3595@1|root,COG3595@2|Bacteria,1VJU7@1239|Firmicutes,4HQ8U@91061|Bacilli,3F6HR@33958|Lactobacillaceae 91061|Bacilli S Putative adhesin - - - - - - - - - - - - DUF4097 PJD2_k127_1315735_12 111780.Sta7437_4231 2.052e-09 69.0 COG0823@1|root,COG0823@2|Bacteria,1GJ0J@1117|Cyanobacteria,3VIZ2@52604|Pleurocapsales 1117|Cyanobacteria QU calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - CBM_6,SdrD_B PJD2_k127_1336133_14 643562.Daes_0067 1.096e-35 137.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria,2M8PA@213115|Desulfovibrionales 28221|Deltaproteobacteria P transporter antisigma-factor antagonist STAS - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp PJD2_k127_1336133_9 264732.Moth_1248 2.801e-102 351.0 COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,42ES8@68295|Thermoanaerobacterales 186801|Clostridia H Belongs to the precorrin methyltransferase family cobA - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 ko:K02302,ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947 RC00003,RC00871,RC01012,RC01034,RC01861 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS15755 HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase PJD2_k127_1336133_16 323261.Noc_0863 2.118e-33 147.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales 135613|Chromatiales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase PJD2_k127_1336133_5 706587.Desti_2669 1.328e-152 495.0 COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2MQS4@213462|Syntrophobacterales 28221|Deltaproteobacteria C PFAM Polysulphide reductase, NrfD dsrP - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD PJD2_k127_1336133_10 335543.Sfum_1149 1.717e-99 331.0 COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MQSD@213462|Syntrophobacterales 28221|Deltaproteobacteria C 4Fe-4S dicluster domain dsrO - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11,Fer4_4 PJD2_k127_1336133_13 706587.Desti_2671 1.615e-39 151.0 arCOG10385@1|root,32SEM@2|Bacteria,1N1IG@1224|Proteobacteria,42TMW@68525|delta/epsilon subdivisions,2WQBW@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - dsrJ - - - - - - - - - - - - PJD2_k127_1336133_0 264732.Moth_1606 6.833e-279 865.0 COG0247@1|root,COG0247@2|Bacteria,1TSC1@1239|Firmicutes,24B10@186801|Clostridia,42FPP@68295|Thermoanaerobacterales 186801|Clostridia C 4Fe-4S dicluster domain hmeD - - - - - - - - - - - CCG,Fer4_8 PJD2_k127_1336133_6 768710.DesyoDRAFT_1676 1.277e-131 427.0 COG2181@1|root,COG2181@2|Bacteria,1UYRK@1239|Firmicutes,24FM8@186801|Clostridia,266ZT@186807|Peptococcaceae 186801|Clostridia C PFAM Nitrate reductase gamma subunit hmeC - - - - - - - - - - - Nitrate_red_gam PJD2_k127_1336133_15 335543.Sfum_1145 3.309e-35 141.0 2CDHP@1|root,32RXU@2|Bacteria,1N1BP@1224|Proteobacteria,42TPT@68525|delta/epsilon subdivisions,2WQE6@28221|Deltaproteobacteria,2MRXY@213462|Syntrophobacterales 28221|Deltaproteobacteria S RsbT co-antagonist protein rsbRD N-terminal domain - - - - - - - - - - - - RsbRD_N PJD2_k127_1336133_12 264732.Moth_1632 3.543e-48 174.0 COG2920@1|root,COG2920@2|Bacteria,1V6WF@1239|Firmicutes,24JRH@186801|Clostridia,42GKQ@68295|Thermoanaerobacterales 186801|Clostridia P TIGRFAM sulfur relay protein, TusE DsrC DsvC family - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC PJD2_k127_1336133_3 331678.Cphamn1_1855 1.487e-168 549.0 COG0493@1|root,COG0493@2|Bacteria,1FDFY@1090|Chlorobi 1090|Chlorobi C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2 PJD2_k127_1336133_7 589865.DaAHT2_1671 3.986e-130 433.0 COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MHZW@213118|Desulfobacterales 28221|Deltaproteobacteria H Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source cbiA - 6.3.5.11,6.3.5.9 ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05224,R05815 RC00010,RC01301 ko00000,ko00001,ko01000 - - - AAA_26,CbiA,GATase_3 PJD2_k127_1336133_4 1121428.DESHY_30086___1 1.625e-159 510.0 COG2221@1|root,COG2221@2|Bacteria,1TZD2@1239|Firmicutes,24DEF@186801|Clostridia,2610K@186807|Peptococcaceae 186801|Clostridia C TIGRFAM sulfite reductase, dissimilatory-type beta subunit dsrB - 1.8.99.5 ko:K11181 ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120 M00596 R00295,R00861,R08035 RC00065,RC01760 ko00000,ko00001,ko00002,ko01000 - - - Fer4,NIR_SIR,NIR_SIR_ferr PJD2_k127_1336133_2 868595.Desca_2666 5.412e-180 572.0 COG2221@1|root,COG2221@2|Bacteria,1TRP0@1239|Firmicutes,24A5T@186801|Clostridia,260BJ@186807|Peptococcaceae 186801|Clostridia C PFAM nitrite and sulphite reductase 4Fe-4S dsrA - 1.8.99.5 ko:K11180 ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120 M00596 R00295,R00861,R08035 RC00065,RC01760 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr PJD2_k127_1336133_8 1265505.ATUG01000002_gene1615 4.169e-110 368.0 COG0247@1|root,COG1150@1|root,COG0247@2|Bacteria,COG1150@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MJHX@213118|Desulfobacterales 28221|Deltaproteobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - CCG,Fer4_8 PJD2_k127_1336133_1 1121472.AQWN01000004_gene885 1.837e-261 836.0 COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,26171@186807|Peptococcaceae 186801|Clostridia C Methyl-viologen-reducing hydrogenase, delta subunit - - - ko:K16886 - - - - ko00000 - - - Fer4,Fer4_9,FlpD,Pyr_redox_2 PJD2_k127_1336133_11 335543.Sfum_1287 3.808e-96 321.0 COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,42NHH@68525|delta/epsilon subdivisions,2WJ6M@28221|Deltaproteobacteria,2MQY4@213462|Syntrophobacterales 28221|Deltaproteobacteria C FAD dependent oxidoreductase qmoA - - ko:K16885 - - - - ko00000 - - - FAD_oxidored,NAD_binding_8,Pyr_redox_2 PJD2_k127_1338734_8 1293597.BN147_08010 4.31e-05 55.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,3F3PS@33958|Lactobacillaceae 91061|Bacilli K Fibronectin-binding protein FbpA - - - - - - - - - - - DUF814,FbpA PJD2_k127_1338734_5 379066.GAU_1690 2.209e-58 213.0 COG1561@1|root,COG1561@2|Bacteria,1ZT99@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Domain of unknown function (DUF1732) - - - - - - - - - - - - DUF1732,YicC_N PJD2_k127_1338734_6 555079.Toce_1022 9.025e-53 194.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,42ENR@68295|Thermoanaerobacterales 186801|Clostridia F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin PJD2_k127_1338734_1 717605.Theco_2187 1.19e-111 373.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein PJD2_k127_1338734_4 316067.Geob_3525 1.055e-64 230.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,43TTD@69541|Desulfuromonadales 28221|Deltaproteobacteria L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG PJD2_k127_1338734_0 635013.TherJR_2972 1.502e-143 468.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae 186801|Clostridia L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C PJD2_k127_1338734_3 1379698.RBG1_1C00001G0978 8.388e-68 241.0 COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria 2|Bacteria Q ABC-type transport system involved in resistance to organic solvents permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE PJD2_k127_1338734_2 1379698.RBG1_1C00001G0979 8.221e-96 319.0 COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria 2|Bacteria Q ABC-type transport system involved in resistance to organic solvents, ATPase component mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran PJD2_k127_1338734_7 1379270.AUXF01000007_gene1059 6.812e-13 72.0 COG1463@1|root,COG1463@2|Bacteria,1ZUJC@142182|Gemmatimonadetes 142182|Gemmatimonadetes Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD PJD2_k127_1350501_20 234267.Acid_6183 2.326e-23 108.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Sulfatase PJD2_k127_1350501_4 1379698.RBG1_1C00001G0202 1.922e-97 329.0 COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 PJD2_k127_1350501_12 1379698.RBG1_1C00001G0208 2.682e-55 218.0 COG2304@1|root,COG2304@2|Bacteria,2NPT8@2323|unclassified Bacteria 2|Bacteria S Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA PJD2_k127_1350501_6 536227.CcarbDRAFT_4777 2.182e-86 301.0 COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae 186801|Clostridia S Threonyl alanyl tRNA synthetase SAD - - - ko:K07050 - - - - ko00000,ko01000,ko03016 - - - tRNA-synt_2c,tRNA_SAD PJD2_k127_1350501_0 760568.Desku_0175 1.425e-246 807.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,2600Y@186807|Peptococcaceae 186801|Clostridia L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF PJD2_k127_1350501_22 518766.Rmar_0280 4.541e-17 95.0 COG0760@1|root,COG0760@2|Bacteria,4P6YB@976|Bacteroidetes 976|Bacteroidetes O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase PJD2_k127_1350501_17 443143.GM18_0166 6.969e-35 147.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,43T4C@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03769,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 PJD2_k127_1350501_16 290398.Csal_0918 2.089e-35 151.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1XICE@135619|Oceanospirillales 135619|Oceanospirillales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N PJD2_k127_1350501_23 459349.CLOAM0180 4.641e-12 72.0 COG1188@1|root,COG1188@2|Bacteria,2NQ1V@2323|unclassified Bacteria 2|Bacteria J S4 RNA-binding domain yabO GO:0008150,GO:0040007 - - - - - - - - - - DUF3558,S4 PJD2_k127_1350501_9 518766.Rmar_1652 1.187e-69 248.0 COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1FIZN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA PJD2_k127_1350501_8 1209989.TepiRe1_1785 1.244e-70 252.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,42EW3@68295|Thermoanaerobacterales 186801|Clostridia D TIGRFAM Cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran PJD2_k127_1350501_15 401526.TcarDRAFT_0543 3.365e-40 160.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes 909932|Negativicutes D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX PJD2_k127_1350501_13 1379698.RBG1_1C00001G0315 2.27e-53 207.0 COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria 2|Bacteria D Peptidase family M23 envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 PJD2_k127_1350501_11 1088721.NSU_1615 3.992e-60 217.0 COG1432@1|root,COG1432@2|Bacteria,1RJ15@1224|Proteobacteria,2UCYU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S NYN domain - - - - - - - - - - - - NYN PJD2_k127_1350501_19 309807.SRU_0857 2.698e-29 130.0 COG2812@1|root,COG2812@2|Bacteria,4PKEA@976|Bacteroidetes,1FJ1I@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L DNA polymerase III, delta subunit - - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 PJD2_k127_1350501_21 1047013.AQSP01000058_gene2028 1.417e-17 95.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - DUF5128,TolB_like PJD2_k127_1350501_25 589865.DaAHT2_0631 9.415e-07 57.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2MHVS@213118|Desulfobacterales 28221|Deltaproteobacteria M Mechanosensitive ion channel mscS-2 - - - - - - - - - - - MS_channel PJD2_k127_1350501_14 545276.KB898726_gene1232 6.249e-52 196.0 COG2430@1|root,COG2430@2|Bacteria,1N0R1@1224|Proteobacteria,1SQ9A@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_1350501_5 396588.Tgr7_0569 8.55e-94 320.0 COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,1T1Q9@1236|Gammaproteobacteria,1WZXW@135613|Chromatiales 135613|Chromatiales M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel PJD2_k127_1350501_2 1047013.AQSP01000110_gene67 1.87e-119 393.0 COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria 2|Bacteria P CorA-like Mg2+ transporter protein corA GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA PJD2_k127_1350501_18 32057.KB217480_gene8266 8.176e-31 133.0 28KW4@1|root,2ZACH@2|Bacteria,1G2SE@1117|Cyanobacteria,1HT4Q@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - PJD2_k127_1350501_1 1122216.AUHW01000012_gene1509 1.139e-148 488.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H2FJ@909932|Negativicutes 909932|Negativicutes J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind PJD2_k127_1350501_7 289376.THEYE_A1260 2.107e-77 275.0 COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,3J0KM@40117|Nitrospirae 40117|Nitrospirae L TatD related DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - Fer4_14,Radical_SAM,TatD_DNase PJD2_k127_1350501_10 1120973.AQXL01000129_gene2458 2.266e-67 246.0 COG0702@1|root,COG0702@2|Bacteria,1TT3N@1239|Firmicutes,4HB09@91061|Bacilli 91061|Bacilli GM NAD(P)H-binding - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - NAD_binding_10 PJD2_k127_1350501_3 1499967.BAYZ01000195_gene3106 1.212e-109 373.0 COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria 2|Bacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase MA20_19960 - - - - - - - - - - - PMT_2 PJD2_k127_1350501_26 1150474.JQJI01000027_gene967 8.898e-05 53.0 COG1404@1|root,COG1404@2|Bacteria,2GCI9@200918|Thermotogae 200918|Thermotogae O Belongs to the peptidase S8 family - - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 PJD2_k127_1353122_4 28072.Nos7524_3258 2.781e-58 218.0 COG1572@1|root,COG1864@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1GQ08@1117|Cyanobacteria,1HRMZ@1161|Nostocales 1117|Cyanobacteria U PKD domain - - - - - - - - - - - - CARDB,Calx-beta,PKD,RHS_repeat PJD2_k127_1353122_10 880073.Calab_2377 7.8e-17 93.0 COG1404@1|root,COG3637@1|root,COG1404@2|Bacteria,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety msp3 - - - - - - - - - - - SLH,Surface_Ag_2 PJD2_k127_1353122_8 667632.KB890172_gene4003 7.267e-29 119.0 2C19F@1|root,32ZRH@2|Bacteria,1NJ8W@1224|Proteobacteria,2WIIC@28216|Betaproteobacteria,1K8DV@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_1353122_9 313594.PI23P_07525 2.558e-18 93.0 28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia,3VWFS@52959|Polaribacter 976|Bacteroidetes - - - - - - - - - - - - - - - PJD2_k127_1353122_6 1197477.IA57_04815 8.488e-50 182.0 28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1I177@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the UPF0403 family yqiW - - - - - - - - - - - Disulph_isomer PJD2_k127_1353122_7 616991.JPOO01000003_gene2621 2.469e-33 136.0 COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia,23HF9@178469|Arenibacter 976|Bacteroidetes S Pfam:DUF59 yitW - - - - - - - - - - - FeS_assembly_P PJD2_k127_1353122_5 1183438.GKIL_1934 3.358e-51 193.0 COG0822@1|root,COG0822@2|Bacteria,1G590@1117|Cyanobacteria 1117|Cyanobacteria C SUF system FeS assembly protein, NifU family - - - ko:K04488 - - - - ko00000 - - - NifU_N PJD2_k127_1353122_1 1382359.JIAL01000001_gene681 3.107e-179 570.0 COG0520@1|root,COG0520@2|Bacteria,3Y2SC@57723|Acidobacteria,2JKJX@204432|Acidobacteriia 204432|Acidobacteriia E Aminotransferase class-V - - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 PJD2_k127_1353122_2 323261.Noc_2488 1.475e-114 387.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,1WWK5@135613|Chromatiales 135613|Chromatiales O FeS assembly protein SufD - - - ko:K09015 - - - - ko00000 - - - UPF0051 PJD2_k127_1353122_3 945713.IALB_2894 9.814e-112 366.0 COG0396@1|root,COG0396@2|Bacteria 2|Bacteria O ATPase activity sufC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - ko:K09013 - - - - ko00000,ko02000 - - iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710 ABC_tran PJD2_k127_1353122_0 234267.Acid_7699 2.767e-255 793.0 COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria 57723|Acidobacteria O Uncharacterized protein family (UPF0051) - - - ko:K09014 - - - - ko00000 - - - UPF0051 PJD2_k127_1353122_11 1340493.JNIF01000003_gene3636 0.000361 53.0 COG0457@1|root,COG0457@2|Bacteria 1340493.JNIF01000003_gene3636|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - PJD2_k127_136894_1 1379698.RBG1_1C00001G0505 2.221e-122 428.0 COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria 2|Bacteria E Peptidase family M1 domain - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 PJD2_k127_136894_8 880073.Calab_1679 6.955e-29 119.0 COG0347@1|root,COG0347@2|Bacteria,2NRH8@2323|unclassified Bacteria 2|Bacteria K Belongs to the P(II) protein family - - - ko:K02806,ko:K04752 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - P-II PJD2_k127_136894_12 317025.Tcr_0030 4.184e-08 66.0 COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,1RRM1@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger PJD2_k127_136894_7 439235.Dalk_0142 3.789e-56 213.0 COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,42RF1@68525|delta/epsilon subdivisions,2WMJJ@28221|Deltaproteobacteria,2MJ88@213118|Desulfobacterales 28221|Deltaproteobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger,PTS_EIIA_2,TrkA_C,TrkA_N PJD2_k127_136894_0 404380.Gbem_3413 2.999e-149 485.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43TS4@69541|Desulfuromonadales 28221|Deltaproteobacteria T response regulator - - - ko:K02481,ko:K07715 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_136894_6 1379698.RBG1_1C00001G0578 8.252e-63 233.0 COG3852@1|root,COG3852@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.13.3 ko:K10942 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9 PJD2_k127_136894_10 1001530.BACE01000028_gene3925 1.444e-14 79.0 COG4719@1|root,COG4719@2|Bacteria,1N3PM@1224|Proteobacteria,1SF72@1236|Gammaproteobacteria,1XXJH@135623|Vibrionales 135623|Vibrionales S protein conserved in bacteria - - - - - - - - - - - - DUF11 PJD2_k127_136894_4 1330700.JQNC01000003_gene722 9.017e-114 400.0 COG1470@1|root,COG4719@1|root,COG1470@2|Bacteria,COG4719@2|Bacteria,1WJNZ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Domain of unknown function DUF11 - - - - - - - - - - - - DUF11 PJD2_k127_136894_9 748658.KB907315_gene2626 4.006e-16 95.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S75T@1236|Gammaproteobacteria,1X1FQ@135613|Chromatiales 135613|Chromatiales N OmpA family - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA PJD2_k127_136894_5 404380.Gbem_2718 1.162e-76 295.0 COG1361@1|root,COG2885@1|root,COG4719@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,COG4719@2|Bacteria,1QW22@1224|Proteobacteria 1224|Proteobacteria M Ompa motb domain protein - - - - - - - - - - - - DUF11,OmpA,SdrD_B PJD2_k127_136894_11 316274.Haur_3265 1.348e-12 83.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,2G7HM@200795|Chloroflexi,375CA@32061|Chloroflexia 32061|Chloroflexia M PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - Peptidase_S8 PJD2_k127_136894_13 1454202.PPBDW_100228___1 1.135e-05 60.0 COG1361@1|root,COG1404@1|root,COG2304@1|root,COG3210@1|root,COG3291@1|root,COG3292@1|root,COG3391@1|root,COG4547@1|root,COG4719@1|root,COG4932@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG2304@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3292@2|Bacteria,COG3391@2|Bacteria,COG4547@2|Bacteria,COG4719@2|Bacteria,COG4932@2|Bacteria,1R59C@1224|Proteobacteria,1SDEC@1236|Gammaproteobacteria,1XWCY@135623|Vibrionales 1236|Gammaproteobacteria MOT alginic acid biosynthetic process - - - - - - - - - - - - DUF11,SdrD_B PJD2_k127_136894_3 880073.Calab_1322 4.775e-118 388.0 COG0330@1|root,COG0330@2|Bacteria,2NP3W@2323|unclassified Bacteria 2|Bacteria O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 PJD2_k127_136894_2 880073.Calab_1323 5.387e-119 389.0 COG0330@1|root,COG0330@2|Bacteria,2NP2X@2323|unclassified Bacteria 2|Bacteria O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 PJD2_k127_1454305_1 391625.PPSIR1_22466 4.035e-136 445.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,433Y1@68525|delta/epsilon subdivisions,2X41I@28221|Deltaproteobacteria,2YXYJ@29|Myxococcales 28221|Deltaproteobacteria S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_1454305_0 391625.PPSIR1_22471 8.142e-146 479.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YXKT@29|Myxococcales 28221|Deltaproteobacteria S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_1454305_2 575540.Isop_2113 1.595e-56 210.0 COG1131@1|root,COG1131@2|Bacteria,2IZF2@203682|Planctomycetes 203682|Planctomycetes V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran PJD2_k127_1454305_3 575540.Isop_2111 6.595e-40 155.0 COG1131@1|root,COG1131@2|Bacteria,2IZ5V@203682|Planctomycetes 203682|Planctomycetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran PJD2_k127_1458356_0 378806.STAUR_0479 3.26e-44 180.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria,2YXVG@29|Myxococcales 28221|Deltaproteobacteria O PA domain - - 3.4.21.62 ko:K01342,ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Inhibitor_I9,PA,Peptidase_S8 PJD2_k127_1458356_1 1267533.KB906735_gene4847 9.247e-22 96.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity MA20_19960 - - - - - - - - - - - PMT_2 PJD2_k127_147598_5 1191523.MROS_1467 1.11e-41 173.0 COG0760@1|root,COG0760@2|Bacteria 2|Bacteria O peptidyl-prolyl cis-trans isomerase activity ppiD - 5.2.1.8 ko:K01802,ko:K03769,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3 PJD2_k127_147598_4 1121930.AQXG01000001_gene1073 1.726e-43 181.0 COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1INUW@117747|Sphingobacteriia 976|Bacteroidetes M Peptidase, M23 - - - - - - - - - - - - Peptidase_M23 PJD2_k127_147598_0 1379698.RBG1_1C00001G0460 0.0 1086.0 COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria 2|Bacteria L DNA polymerase dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon PJD2_k127_147598_6 1379698.RBG1_1C00001G1526 8.54e-31 135.0 2CBA8@1|root,30BZT@2|Bacteria,2NR2H@2323|unclassified Bacteria 2|Bacteria S Exopolysaccharide biosynthesis protein YbjH - - - - - - - - - - - - YjbH PJD2_k127_147598_1 1158760.AQXP01000054_gene1595 8.494e-113 373.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1WX6T@135613|Chromatiales 135613|Chromatiales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA PJD2_k127_147598_7 760142.Hipma_0205 3.301e-14 74.0 COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria,2M7FV@213113|Desulfurellales 28221|Deltaproteobacteria S Trm112p-like protein - - - ko:K09791 - - - - ko00000 - - - Trm112p PJD2_k127_147598_2 1379698.RBG1_1C00001G1789 1.847e-107 391.0 COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria 2|Bacteria S Propeptide_C25 porU - - - - - - - - - - - Peptidase_C25 PJD2_k127_147598_3 880073.Calab_1394 2.918e-53 200.0 COG2067@1|root,COG2067@2|Bacteria,2NPQZ@2323|unclassified Bacteria 2|Bacteria I Two component regulator propeller porV - - - - - - - - - - - - PJD2_k127_1481850_8 1379698.RBG1_1C00001G1819 9.736e-14 85.0 28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_1481850_9 880073.Calab_0646 2.966e-13 83.0 COG1572@1|root,COG1595@1|root,COG1572@2|Bacteria,COG1595@2|Bacteria,2NRE4@2323|unclassified Bacteria 2|Bacteria K Evidence 5 No homology to any previously reported sequences - - - ko:K03088 - - - - ko00000,ko03021 - - - CARDB,Sigma70_r4_2 PJD2_k127_1481850_5 880073.Calab_2402 1.562e-19 104.0 28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_1481850_7 880073.Calab_2081 1.272e-16 94.0 COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria 2|Bacteria P LVIVD repeat - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - LVIVD PJD2_k127_1481850_1 927704.SELR_06060 1.209e-120 399.0 COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H2VM@909932|Negativicutes 909932|Negativicutes I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE PJD2_k127_1481850_6 1173024.KI912149_gene6250 6.902e-18 90.0 2DNMG@1|root,32Y46@2|Bacteria,1GI2P@1117|Cyanobacteria,1JM3Q@1189|Stigonemataceae 1117|Cyanobacteria - - - - - - - - - - - - - - - PJD2_k127_1481850_4 941449.dsx2_1885 8.194e-22 106.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2M97J@213115|Desulfovibrionales 28221|Deltaproteobacteria T PFAM ATP-binding region ATPase domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg PJD2_k127_1481850_3 1265505.ATUG01000001_gene3347 3.72e-34 148.0 COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions 1224|Proteobacteria T histidine kinase A domain protein - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9 PJD2_k127_1481850_10 643562.Daes_0841 1.039e-10 74.0 COG2197@1|root,COG2197@2|Bacteria,1N5S2@1224|Proteobacteria,42UVI@68525|delta/epsilon subdivisions,2WQ89@28221|Deltaproteobacteria,2MA9X@213115|Desulfovibrionales 28221|Deltaproteobacteria K SMART regulatory protein LuxR - - - - - - - - - - - - GerE,PAS_4,PAS_8,PAS_9 PJD2_k127_1481850_2 767817.Desgi_1600 3.385e-42 174.0 COG2202@1|root,COG3829@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,249RN@186801|Clostridia,264BR@186807|Peptococcaceae 186801|Clostridia T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - 5TM-5TMR_LYT,HATPase_c,HisKA,MASE3,PAS_4,PAS_9 PJD2_k127_1481850_0 1232410.KI421415_gene2961 7.167e-157 518.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,43S4V@69541|Desulfuromonadales 28221|Deltaproteobacteria L GIY-YIG type nucleases (URI domain) uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N PJD2_k127_1481850_11 1506583.JQJY01000008_gene4063 8.935e-07 59.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,2P0MK@237|Flavobacterium 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y PJD2_k127_1500722_0 1047013.AQSP01000138_gene1021 1.756e-270 841.0 COG0008@1|root,COG0008@2|Bacteria,2NNRW@2323|unclassified Bacteria 2|Bacteria J tRNA synthetases class I (E and Q), anti-codon binding domain glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C PJD2_k127_1500722_4 379066.GAU_3853 1.962e-73 258.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1ZTKD@142182|Gemmatimonadetes 142182|Gemmatimonadetes KQ helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5,Methyltransf_11 PJD2_k127_1500722_1 861299.J421_2862 1.134e-251 783.0 COG0499@1|root,COG0499@2|Bacteria,1ZTEF@142182|Gemmatimonadetes 142182|Gemmatimonadetes H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD PJD2_k127_1500722_5 234267.Acid_1797 1.339e-46 173.0 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4440,SnoaL_2,SnoaL_4 PJD2_k127_1500722_2 227377.CBU_2024 1.475e-132 430.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1JCEE@118969|Legionellales 118969|Legionellales E Pyridoxal-phosphate dependent enzyme cysK - 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP PJD2_k127_1500722_3 1254432.SCE1572_39205 2.333e-87 296.0 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2WUIA@28221|Deltaproteobacteria,2YV7F@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the MtfA family - - - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 PJD2_k127_1500722_6 1313301.AUGC01000007_gene578 6.635e-44 171.0 COG0458@1|root,COG0458@2|Bacteria 2|Bacteria F carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - - - - - - - - - - ATP-grasp_4 PJD2_k127_1563766_5 682795.AciX8_3881 2.322e-81 282.0 COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia 204432|Acidobacteriia M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M PJD2_k127_1563766_8 398767.Glov_0671 7.959e-64 242.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,43TAE@69541|Desulfuromonadales 28221|Deltaproteobacteria D Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE PJD2_k127_1563766_10 671143.DAMO_2297 1.249e-60 236.0 COG0707@1|root,COG0707@2|Bacteria,2NP4Z@2323|unclassified Bacteria 2|Bacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 iLJ478.TM0232,iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Glyco_tran_28_C,Glyco_transf_28 PJD2_k127_1563766_2 316067.Geob_0781 2.055e-153 499.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,43T1G@69541|Desulfuromonadales 28221|Deltaproteobacteria M UDP-N-acetylmuramate-L-alanine ligase activity murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M PJD2_k127_1563766_6 1120971.AUCA01000030_gene30 7.731e-69 245.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,2785S@186823|Alicyclobacillaceae 91061|Bacilli M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C PJD2_k127_1563766_18 502025.Hoch_5216 2.327e-14 82.0 COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,2YVR5@29|Myxococcales 28221|Deltaproteobacteria D Cell division protein FtsQ ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 PJD2_k127_1563766_3 1121456.ATVA01000012_gene2721 9.912e-111 371.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2M85X@213115|Desulfovibrionales 28221|Deltaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA PJD2_k127_1563766_4 1125863.JAFN01000001_gene3353 6.445e-107 362.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin PJD2_k127_1563766_11 593750.Metfor_1649 7.66e-38 162.0 COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03038@2157|Archaea,arCOG03042@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAN4@224756|Methanomicrobia 224756|Methanomicrobia S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 PJD2_k127_1563766_17 177437.HRM2_12300 3.301e-17 86.0 COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MKZY@213118|Desulfobacterales 28221|Deltaproteobacteria J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0003674,GO:0003735,GO:0005198 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 PJD2_k127_1563766_1 635013.TherJR_2099 1.205e-177 579.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae 186801|Clostridia L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge PJD2_k127_1563766_21 1121441.AUCX01000016_gene2341 0.0002073 50.0 2AKQ6@1|root,31BGX@2|Bacteria,1RCS3@1224|Proteobacteria,43CC0@68525|delta/epsilon subdivisions,2X7XS@28221|Deltaproteobacteria,2MHJ4@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4 PJD2_k127_1563766_20 316067.Geob_2164 2.193e-06 56.0 COG0745@1|root,COG0745@2|Bacteria,1NV0N@1224|Proteobacteria,42ZH3@68525|delta/epsilon subdivisions,2WUW0@28221|Deltaproteobacteria,43UQG@69541|Desulfuromonadales 28221|Deltaproteobacteria T zinc-ribbon domain - - - - - - - - - - - - Response_reg,zinc_ribbon_4 PJD2_k127_1563766_14 1499967.BAYZ01000074_gene2082 1.18e-24 115.0 COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - 2.7.11.1,2.7.7.65 ko:K02488,ko:K04757 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021 - - - HATPase_c,HATPase_c_2,HisKA,Response_reg PJD2_k127_1563766_19 1173024.KI912148_gene3814 5.958e-12 78.0 COG0477@1|root,COG2814@2|Bacteria,1G02H@1117|Cyanobacteria,1JHBH@1189|Stigonemataceae 1117|Cyanobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 PJD2_k127_1563766_7 391625.PPSIR1_33044 1.832e-66 246.0 COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales 28221|Deltaproteobacteria S ADP-ribosylation factor family mglA GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - ko:K06883 - - - - ko00000 - - - Arf,Ras PJD2_k127_1563766_12 1173029.JH980292_gene2288 3.909e-35 149.0 COG0457@1|root,COG0457@2|Bacteria,1GD9N@1117|Cyanobacteria,1HH3D@1150|Oscillatoriales 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 PJD2_k127_1563766_16 1379698.RBG1_1C00001G1726 2.003e-23 115.0 29YZ1@1|root,30KVZ@2|Bacteria,2NRNQ@2323|unclassified Bacteria 2|Bacteria S Capsule assembly protein Wzi - - - - - - - - - - - - Caps_assemb_Wzi PJD2_k127_1563766_13 1448860.BBJO01000069_gene1874 9.762e-31 132.0 COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,23SVZ@183963|Halobacteria 183963|Halobacteria I Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids ubiA2 - 2.5.1.42 ko:K17105 ko00564,map00564 - R04520 RC01171 ko00000,ko00001,ko01000 - - - UbiA PJD2_k127_1563766_9 1123276.KB893279_gene2202 2.503e-61 222.0 COG0823@1|root,COG0823@2|Bacteria,4NITC@976|Bacteroidetes,47R0N@768503|Cytophagia 976|Bacteroidetes U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 PJD2_k127_1563766_15 1121931.AUHG01000016_gene1129 1.087e-23 105.0 COG0346@1|root,COG0346@2|Bacteria,4NZ7E@976|Bacteroidetes 976|Bacteroidetes E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase PJD2_k127_1563766_0 1449126.JQKL01000059_gene1850 7.649e-271 854.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,26839@186813|unclassified Clostridiales 186801|Clostridia J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 PJD2_k127_1576733_2 118163.Ple7327_4014 1.003e-111 367.0 COG2225@1|root,COG2225@2|Bacteria,1G2A4@1117|Cyanobacteria 1117|Cyanobacteria C PFAM Malate synthase - - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase PJD2_k127_1576733_1 926562.Oweho_1533 2.643e-128 420.0 COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1HXUV@117743|Flavobacteriia,2PAT3@246874|Cryomorphaceae 976|Bacteroidetes H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase PJD2_k127_1576733_3 4432.XP_010265911.1 2.296e-109 369.0 COG0372@1|root,KOG2617@2759|Eukaryota,37JED@33090|Viridiplantae,3GF4T@35493|Streptophyta 35493|Streptophyta C Belongs to the citrate synthase family - GO:0000166,GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009507,GO:0009536,GO:0009987,GO:0010035,GO:0010038,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0019752,GO:0030312,GO:0030554,GO:0031974,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036440,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046686,GO:0046872,GO:0046912,GO:0046914,GO:0050896,GO:0055114,GO:0070013,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt PJD2_k127_1576733_6 998674.ATTE01000001_gene3104 3.468e-24 112.0 2E7GU@1|root,331ZI@2|Bacteria,1NEDQ@1224|Proteobacteria,1SG7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4184) - - - - - - - - - - - - DUF4184 PJD2_k127_1576733_0 945713.IALB_1150 6.81e-235 742.0 COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria 2|Bacteria E 3-isopropylmalate dehydratase activity leuD - 4.2.1.33,4.2.1.35,4.2.1.36 ko:K01703,ko:K01704,ko:K01705 ko00290,ko00300,ko00660,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00966,map01100,map01110,map01120,map01130,map01210,map01230 M00030,M00432,M00433,M00535 R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C PJD2_k127_1576733_4 1125863.JAFN01000001_gene1105 1.134e-74 258.0 COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,42Q5T@68525|delta/epsilon subdivisions,2WKN4@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Belongs to the UPF0173 family - - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 PJD2_k127_1576733_5 1232410.KI421421_gene3541 1.046e-28 120.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,42WGY@68525|delta/epsilon subdivisions,2WS4W@28221|Deltaproteobacteria,43VDK@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tellurite resistance protein TerB - - - - - - - - - - - - TerB PJD2_k127_1576733_7 1215114.BBIU01000040_gene3969 3.666e-11 63.0 COG0179@1|root,COG0179@2|Bacteria,1MW82@1224|Proteobacteria,1RQYW@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) fahA - 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_4620 FAA_hydrolase,FAA_hydrolase_N PJD2_k127_1578690_0 1095769.CAHF01000011_gene2424 5.3e-304 937.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,47361@75682|Oxalobacteraceae 28216|Betaproteobacteria C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C PJD2_k127_1578690_1 1231391.AMZF01000025_gene1378 8.421e-08 55.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,3T2B6@506|Alcaligenaceae 28216|Betaproteobacteria C SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 sdhB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17,Fer4_8 PJD2_k127_1599615_1 935261.JAGL01000015_gene3755 7.205e-18 96.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TQUY@28211|Alphaproteobacteria,43JD1@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B PJD2_k127_1599615_2 1105029.HMPREF1137_1392 2.217e-08 66.0 COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,2I66Z@201174|Actinobacteria,4D38B@85005|Actinomycetales 201174|Actinobacteria M SdrD B-like domain - - - - - - - - - - - - DUF11,SdrD_B PJD2_k127_1599615_0 1379698.RBG1_1C00001G1218 4.38e-30 123.0 COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria 2|Bacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase,TPR_8 PJD2_k127_1610082_4 880073.Calab_3296 1.203e-20 108.0 COG0737@1|root,COG0737@2|Bacteria 2|Bacteria F nucleotide catabolic process - - 3.4.17.18 ko:K05996 - - - - ko00000,ko01000,ko01002 - - - 5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH PJD2_k127_1610082_0 880073.Calab_1111 3.7e-116 408.0 COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria 2|Bacteria E aminopeptidase pepN1 - - - - - - - - - - - Peptidase_M1 PJD2_k127_1610082_3 398578.Daci_4841 3.886e-35 147.0 COG0457@1|root,COG0457@2|Bacteria,1NZ46@1224|Proteobacteria 1224|Proteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - PJD2_k127_1610082_2 349124.Hhal_0421 1.335e-61 233.0 COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,1T3FR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function(DUF2779) - - - - - - - - - - - - DUF2779 PJD2_k127_1685966_2 234267.Acid_6601 1.831e-48 195.0 COG0265@1|root,COG2203@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria 57723|Acidobacteria KT Sigma factor PP2C-like phosphatases - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - GAF_3,RibD_C,SpoIIE PJD2_k127_1685966_3 880073.Calab_0829 1.258e-14 78.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane PJD2_k127_1685966_1 420324.KI911943_gene5343 2.434e-66 237.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 PJD2_k127_1685966_0 644282.Deba_1534 4.091e-92 316.0 COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N PJD2_k127_1745941_0 1123320.KB889731_gene6103 2.737e-38 164.0 COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2IAZ2@201174|Actinobacteria 201174|Actinobacteria KLT PQQ enzyme repeat - - 1.1.2.6,2.7.11.1 ko:K05889,ko:K12132 - - R03136 - ko00000,ko01000,ko01001 - - - PQQ,PQQ_2,PQQ_3,Pkinase PJD2_k127_1745941_3 1089553.Tph_c21100 1.522e-10 69.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,42ESV@68295|Thermoanaerobacterales 186801|Clostridia O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG PJD2_k127_1745941_1 5911.EAR82403 3.062e-19 98.0 COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora 5878|Ciliophora GOT TPR Domain containing protein - - - ko:K12600 ko03018,map03018 M00392 - - ko00000,ko00001,ko00002,ko03019 - - - TPR_1,TPR_11,TPR_2,TPR_8 PJD2_k127_1745941_2 555779.Dthio_PD2047 6.051e-18 95.0 COG0170@1|root,COG0170@2|Bacteria 2|Bacteria I dolichyl monophosphate biosynthetic process sec59 - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf PJD2_k127_1774629_3 686340.Metal_3843 8.736e-45 168.0 COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,1T460@1236|Gammaproteobacteria,1XEF0@135618|Methylococcales 135618|Methylococcales S Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - - PJD2_k127_1774629_0 441620.Mpop_4542 6.861e-79 267.0 COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria,1JUR8@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM Glyoxalase bleomycin resistance protein dioxygenase MA20_22790 - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase PJD2_k127_1774629_2 1379698.RBG1_1C00001G0109 1.554e-57 211.0 COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria 2|Bacteria U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 PJD2_k127_1774629_1 1379698.RBG1_1C00001G0108 2.587e-73 257.0 COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria 2|Bacteria P Belongs to the bacterial solute-binding protein 9 family znuA - - ko:K02077,ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA PJD2_k127_1774629_4 404589.Anae109_1534 9.533e-21 106.0 COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2WRZ7@28221|Deltaproteobacteria,2YYH9@29|Myxococcales 28221|Deltaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - PJD2_k127_1795903_9 313612.L8106_14875 1.4e-14 82.0 COG0474@1|root,COG0474@2|Bacteria,1G2KF@1117|Cyanobacteria,1H9NM@1150|Oscillatoriales 1117|Cyanobacteria P Cation transport ATPase - - 3.6.3.6,3.6.3.8 ko:K01535,ko:K01537 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.2,3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase PJD2_k127_1795903_7 595460.RRSWK_05375 5.55e-26 122.0 COG3074@1|root,COG3074@2|Bacteria 2|Bacteria D FtsZ-dependent cytokinesis - - - - - - - - - - - - - PJD2_k127_1795903_2 224325.AF_0367 3.764e-84 297.0 COG0477@1|root,arCOG00147@2157|Archaea,2XTS8@28890|Euryarchaeota,246N5@183980|Archaeoglobi 183980|Archaeoglobi G Major Facilitator Superfamily - - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 PJD2_k127_1795903_0 56110.Oscil6304_1708 7.314e-138 449.0 COG0438@1|root,COG0438@2|Bacteria,1G2DD@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Glycosyl transferases group 1 - - - ko:K16703 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 PJD2_k127_1795903_4 56110.Oscil6304_1713 1.301e-51 195.0 COG5653@1|root,COG5653@2|Bacteria,1GC7U@1117|Cyanobacteria,1HEMP@1150|Oscillatoriales 1117|Cyanobacteria M FemAB family - - - - - - - - - - - - Acetyltransf_6 PJD2_k127_1795903_3 56110.Oscil6304_1711 5.167e-57 206.0 COG2227@1|root,COG2227@2|Bacteria,1GQ6N@1117|Cyanobacteria 1117|Cyanobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 PJD2_k127_1795903_5 1088721.NSU_1311 9.089e-34 146.0 28HYD@1|root,2Z83U@2|Bacteria,1R5TY@1224|Proteobacteria,2UUD5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 PJD2_k127_1795903_8 595536.ADVE02000001_gene2759 3.896e-19 99.0 COG0297@1|root,COG0297@2|Bacteria,1RH73@1224|Proteobacteria,2UA8P@28211|Alphaproteobacteria,370WC@31993|Methylocystaceae 28211|Alphaproteobacteria G transferase activity, transferring glycosyl groups - - - - - - - - - - - - Methyltransf_24 PJD2_k127_1795903_1 521011.Mpal_0174 1.285e-87 307.0 COG2244@1|root,arCOG02209@2157|Archaea,2XU81@28890|Euryarchaeota 28890|Euryarchaeota S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328,ko:K16695 - - - - ko00000,ko02000 2.A.66.2,2.A.66.2.7 - - Polysacc_synt_3,Polysacc_synt_C PJD2_k127_1795903_6 203124.Tery_2515 3.221e-29 122.0 COG0367@1|root,COG0367@2|Bacteria 2|Bacteria E asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 PJD2_k127_1797898_0 717231.Flexsi_0532 3.884e-210 660.0 COG4799@1|root,COG4799@2|Bacteria,2GEP0@200930|Deferribacteres 200930|Deferribacteres I Carboxyl transferase domain - - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans PJD2_k127_1797898_2 547042.BACCOPRO_02972 6.534e-160 518.0 COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,2FMBN@200643|Bacteroidia,4ANDX@815|Bacteroidaceae 976|Bacteroidetes I Biotin carboxylase accC - 6.3.4.14,6.4.1.2,6.4.1.3 ko:K01961,ko:K01965 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00373,M00376,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 PJD2_k127_1797898_4 944479.JQLX01000013_gene1446 3.863e-18 100.0 COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2M773@213113|Desulfurellales 28221|Deltaproteobacteria I Biotin-requiring enzyme - - - - - - - - - - - - Biotin_lipoyl PJD2_k127_1797898_1 565033.GACE_0747 1.345e-208 670.0 COG1884@1|root,arCOG04232@2157|Archaea,2XU3F@28890|Euryarchaeota,245QJ@183980|Archaeoglobi 183980|Archaeoglobi I Methylmalonyl-CoA mutase - - 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase PJD2_k127_1797898_3 929712.KI912613_gene896 1.006e-31 130.0 COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria 84995|Rubrobacteria E Glyoxalase bleomycin resistance protein dioxygenase - - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 PJD2_k127_1797898_5 1121405.dsmv_1388 0.0008989 42.0 2APA5@1|root,31EC7@2|Bacteria,1RHMQ@1224|Proteobacteria,42UND@68525|delta/epsilon subdivisions,2WQK4@28221|Deltaproteobacteria,2MM23@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_1836991_2 1121447.JONL01000001_gene692 6.103e-28 121.0 COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42SPW@68525|delta/epsilon subdivisions,2WP7F@28221|Deltaproteobacteria,2M954@213115|Desulfovibrionales 28221|Deltaproteobacteria S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnA - 4.2.1.151 ko:K11782 ko00130,ko01110,map00130,map01110 - R10666 RC03232 ko00000,ko00001,ko01000 - - - VitK2_biosynth PJD2_k127_1836991_1 1385935.N836_22035 5.016e-29 124.0 COG1670@1|root,COG1670@2|Bacteria,1GDUD@1117|Cyanobacteria,1HFNX@1150|Oscillatoriales 1117|Cyanobacteria J PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_3 PJD2_k127_1836991_0 1444309.JAQG01000090_gene1222 1.795e-43 164.0 COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes,4HCM8@91061|Bacilli,26T1J@186822|Paenibacillaceae 91061|Bacilli H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnC - 1.21.98.1 ko:K11784 ko00130,ko01110,map00130,map01110 - R08588 RC02329 ko00000,ko00001,ko01000 - - - Radical_SAM PJD2_k127_184421_16 1131269.AQVV01000019_gene800 1.409e-35 141.0 COG2827@1|root,COG2827@2|Bacteria 2|Bacteria L Endonuclease containing a URI domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG PJD2_k127_184421_8 448385.sce3387 9.772e-97 340.0 COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales 28221|Deltaproteobacteria S cellulose binding - - - - - - - - - - - - - PJD2_k127_184421_10 765420.OSCT_2368 4.355e-79 273.0 COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi,376R3@32061|Chloroflexia 32061|Chloroflexia IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short PJD2_k127_184421_7 880073.Calab_2864 1.299e-100 344.0 COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria 2|Bacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH PJD2_k127_184421_4 1121022.ABENE_13635 3.343e-144 467.0 COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2U0GI@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Filamentation induced by cAMP protein fic - - - - - - - - - - - - Fic,Fic_N PJD2_k127_184421_0 1304885.AUEY01000026_gene3553 1.558e-198 637.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2MHT0@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn PJD2_k127_184421_11 1158182.KB905020_gene1914 1.131e-76 266.0 COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1X0AW@135613|Chromatiales 135613|Chromatiales S Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 PJD2_k127_184421_3 1047013.AQSP01000089_gene1175 4.374e-151 492.0 COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria 2|Bacteria E Cys/Met metabolism PLP-dependent enzyme metC - 2.5.1.48,4.4.1.11,4.4.1.8 ko:K01739,ko:K01760,ko:K01761 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP PJD2_k127_184421_20 1131269.AQVV01000008_gene978 2.066e-13 81.0 COG3011@1|root,COG3011@2|Bacteria 2|Bacteria CH Protein conserved in bacteria - - - - - - - - - - - - DUF393 PJD2_k127_184421_14 498761.HM1_2853 1.511e-43 165.0 COG1595@1|root,COG1595@2|Bacteria,1V3G9@1239|Firmicutes,24G1Y@186801|Clostridia 186801|Clostridia K Belongs to the sigma-70 factor family. ECF subfamily sigZ - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_184421_21 1237149.C900_04012 1.56e-06 56.0 2DQ9W@1|root,335IW@2|Bacteria,4NX9R@976|Bacteroidetes,47SCH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - PJD2_k127_184421_18 1519464.HY22_04465 9.877e-27 121.0 COG1595@1|root,COG1595@2|Bacteria,1FE7H@1090|Chlorobi 1090|Chlorobi K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_184421_22 309801.trd_1051 1.802e-05 53.0 COG5662@1|root,COG5662@2|Bacteria,2GBGZ@200795|Chloroflexi,27XXW@189775|Thermomicrobia 189775|Thermomicrobia K Putative zinc-finger - - - - - - - - - - - - zf-HC2 PJD2_k127_184421_12 28072.Nos7524_2690 2.099e-74 256.0 COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1HK26@1161|Nostocales 1117|Cyanobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 PJD2_k127_184421_23 1229909.NSED_01035 0.0001663 48.0 COG5466@1|root,arCOG05278@2157|Archaea 2157|Archaea S small metal-binding protein - - - - - - - - - - - - DUF1059 PJD2_k127_184421_9 1042877.GQS_06270 1.581e-81 296.0 COG4826@1|root,arCOG04933@2157|Archaea,2XV8M@28890|Euryarchaeota,243MH@183968|Thermococci 183968|Thermococci O SERine Proteinase INhibitors - GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005576,GO:0005615,GO:0008150,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0032268,GO:0032269,GO:0043086,GO:0044092,GO:0044421,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772 - ko:K13963 ko05146,map05146 - - - ko00000,ko00001 - - - Serpin PJD2_k127_184421_13 1089549.AZUQ01000001_gene1504 1.284e-73 256.0 COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4EXQE@85014|Glycomycetales 201174|Actinobacteria L FES nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD PJD2_k127_184421_1 403833.Pmob_0486 1.297e-178 590.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GE9T@200918|Thermotogae 200918|Thermotogae L DNA polymerase alpha chain like domain - - - ko:K02347 - - - - ko00000,ko03400 - - - PHP PJD2_k127_184421_15 523850.TON_0056 4.704e-37 150.0 COG0543@1|root,arCOG02199@2157|Archaea,2XTVJ@28890|Euryarchaeota,243NE@183968|Thermococci 183968|Thermococci C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - 1.8.1.19 ko:K20203 - - - - ko00000,ko01000 - - - DHODB_Fe-S_bind PJD2_k127_184421_6 880073.Calab_1897 2.171e-134 436.0 COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria 2|Bacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 PJD2_k127_184421_2 314230.DSM3645_10052 2.31e-154 505.0 COG0457@1|root,COG0457@2|Bacteria,2IXTF@203682|Planctomycetes 203682|Planctomycetes O Tetratricopeptide repeat - - - - - - - - - - - - AhpC-TSA PJD2_k127_184421_19 1356852.N008_20540 2.813e-25 112.0 2DTU1@1|root,33MMF@2|Bacteria,4NWD8@976|Bacteroidetes,47SX0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - PJD2_k127_184421_5 1242864.D187_009322 7.989e-142 465.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2X9B9@28221|Deltaproteobacteria,2YX2A@29|Myxococcales 28221|Deltaproteobacteria P POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 PJD2_k127_184421_17 1121918.ARWE01000001_gene2477 2.833e-35 146.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2X6EH@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Responsible for synthesis of pseudouridine from uracil - - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 PJD2_k127_1871186_0 1382306.JNIM01000001_gene1023 1.717e-167 542.0 COG1529@1|root,COG1529@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrA - 1.3.7.9 ko:K04108 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 PJD2_k127_1871186_2 370438.PTH_1579 8.471e-43 162.0 COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,26208@186807|Peptococcaceae 186801|Clostridia C Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 PJD2_k127_1871186_1 1379698.RBG1_1C00001G0513 2.353e-145 472.0 COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria 2|Bacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA3 - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like PJD2_k127_1871186_3 641147.HMPREF9021_01354 0.0002006 48.0 2EH3E@1|root,33AVE@2|Bacteria,1NDWJ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - DUF1889 PJD2_k127_1885869_9 1379698.RBG1_1C00001G0231 1.234e-09 68.0 COG1413@1|root,COG1413@2|Bacteria,2NRMK@2323|unclassified Bacteria 2|Bacteria C HEAT repeats CP_0755 - - - - - - - - - - - HEAT_2,HEAT_PBS,Response_reg PJD2_k127_1885869_11 518766.Rmar_2601 6.03e-08 65.0 COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,1FJ20@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 PJD2_k127_1885869_2 926569.ANT_30960 6.344e-100 334.0 COG1951@1|root,COG1951@2|Bacteria,2G6YI@200795|Chloroflexi 200795|Chloroflexi C Fumarate hydratase (Fumerase) - - 4.2.1.2 ko:K01676,ko:K01677 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase PJD2_k127_1885869_4 926569.ANT_30970 4.192e-67 234.0 COG1838@1|root,COG1838@2|Bacteria,2G74D@200795|Chloroflexi 200795|Chloroflexi C Fumarase C-terminus - - 4.2.1.2 ko:K01676,ko:K01678 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase_C PJD2_k127_1885869_7 96561.Dole_1704 9.316e-24 111.0 COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales 1224|Proteobacteria P Parallel beta-helix repeats - - - - - - - - - - - - - PJD2_k127_1885869_8 517418.Ctha_2075 2.922e-22 112.0 COG5184@1|root,COG5492@1|root,COG5184@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - - - - - - - - - - Big_5,Cadherin-like,Glug PJD2_k127_1885869_3 1515613.HQ37_08195 2.405e-67 254.0 COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,2FPCB@200643|Bacteroidia,22W87@171551|Porphyromonadaceae 976|Bacteroidetes C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 PJD2_k127_1885869_1 1047013.AQSP01000140_gene2549 1.469e-235 754.0 COG1067@1|root,COG1067@2|Bacteria,2NP29@2323|unclassified Bacteria 2|Bacteria O peptidase S16 ycbZ - 3.4.21.53 ko:K01338,ko:K04076,ko:K04770 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA_32,Lon_C PJD2_k127_1885869_0 1379698.RBG1_1C00001G0679 6.588e-240 754.0 COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria 2|Bacteria O Carbamoyltransferase C-terminus - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N PJD2_k127_1885869_12 1379698.RBG1_1C00001G0678 1.995e-07 58.0 294GU@1|root,2ZRWK@2|Bacteria,2NRXQ@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_1885869_6 1197906.CAJQ02000047_gene4077 7.547e-37 143.0 COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria,2UEPY@28211|Alphaproteobacteria,3K08M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - - PJD2_k127_1885869_10 309801.trd_0152 3.189e-08 58.0 2EQM1@1|root,33I6Z@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 PJD2_k127_1885869_5 562970.Btus_0781 1.893e-55 224.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4HBU2@91061|Bacilli,2781T@186823|Alicyclobacillaceae 91061|Bacilli G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N PJD2_k127_1885869_13 1382306.JNIM01000001_gene2472 1.939e-05 59.0 COG1418@1|root,COG1418@2|Bacteria,2G77Y@200795|Chloroflexi 200795|Chloroflexi S PFAM metal-dependent phosphohydrolase, HD sub domain - - - ko:K06950 - - - - ko00000 - - - HD PJD2_k127_1895826_3 234267.Acid_1007 1.32e-26 112.0 COG0724@1|root,COG0724@2|Bacteria,3Y59V@57723|Acidobacteria 57723|Acidobacteria S RNA recognition motif - - - - - - - - - - - - RRM_1 PJD2_k127_1895826_1 388467.A19Y_2205 1.033e-63 237.0 COG1011@1|root,COG1011@2|Bacteria,1G4JI@1117|Cyanobacteria,1H8VT@1150|Oscillatoriales 1117|Cyanobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 PJD2_k127_1895826_0 1121405.dsmv_3501 4.619e-78 272.0 COG1801@1|root,COG1801@2|Bacteria,1MXIQ@1224|Proteobacteria,42XHB@68525|delta/epsilon subdivisions,2WSKY@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 PJD2_k127_1895826_2 179408.Osc7112_2637 1.739e-41 158.0 COG0662@1|root,COG0662@2|Bacteria,1G5PK@1117|Cyanobacteria,1HC1C@1150|Oscillatoriales 1117|Cyanobacteria G PFAM Cupin - - - - - - - - - - - - Cupin_2 PJD2_k127_1895826_7 880072.Desac_1567 7.758e-09 65.0 290YH@1|root,2ZNK8@2|Bacteria,1P7TZ@1224|Proteobacteria,433I3@68525|delta/epsilon subdivisions,2WXS0@28221|Deltaproteobacteria,2MSEA@213462|Syntrophobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_1895826_5 443143.GM18_0497 1.168e-18 94.0 2APBA@1|root,31EDH@2|Bacteria,1RIDJ@1224|Proteobacteria 1224|Proteobacteria S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 PJD2_k127_1895826_4 383372.Rcas_3573 8.455e-21 100.0 COG0526@1|root,COG0526@2|Bacteria,2G8YT@200795|Chloroflexi 200795|Chloroflexi CO Thioredoxin - - - - - - - - - - - - Thioredoxin_9 PJD2_k127_1895826_6 1200557.JHWV01000006_gene1883 2.225e-16 80.0 COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4H26Q@909932|Negativicutes 909932|Negativicutes S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 PJD2_k127_1918765_11 269799.Gmet_3156 1.213e-22 102.0 COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2WS29@28221|Deltaproteobacteria,43SQV@69541|Desulfuromonadales 28221|Deltaproteobacteria C Probably plays a role in a hydrogenase nickel cofactor insertion step hypA - - ko:K04651 - - - - ko00000,ko03110 - - - HypA PJD2_k127_1918765_6 1304872.JAGC01000009_gene1110 2.264e-74 258.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,2M883@213115|Desulfovibrionales 28221|Deltaproteobacteria KO Hydrogenase accessory protein HypB hypB - - ko:K04652 - - - - ko00000,ko03110 - - - cobW PJD2_k127_1918765_10 32049.SYNPCC7002_A0205 9.65e-26 109.0 COG0298@1|root,COG0298@2|Bacteria,1G9FZ@1117|Cyanobacteria,1H1PR@1129|Synechococcus 1117|Cyanobacteria O HupF/HypC family hypC - - ko:K04653 - - - - ko00000 - - - HupF_HypC PJD2_k127_1918765_2 518766.Rmar_2595 3.037e-173 550.0 COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes 976|Bacteroidetes O TIGRFAM hydrogenase expression formation protein HypD - - - ko:K04654 - - - - ko00000 - - - HypD PJD2_k127_1918765_5 1191523.MROS_1097 1.065e-97 333.0 COG3203@1|root,COG3203@2|Bacteria 2|Bacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - Alginate_exp,BBP2,MucBP,Porin_4,SLH PJD2_k127_1918765_1 1219065.VPR01S_11_01430 9.453e-182 583.0 COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria,1Y0MK@135623|Vibrionales 135623|Vibrionales C Seven times multi-haem cytochrome CxxCH - - - - - - - - - - - - Cytochrome_C554,Multi-haem_cyto PJD2_k127_1918765_0 945713.IALB_2868 8.69e-231 725.0 COG2986@1|root,COG2986@2|Bacteria 2|Bacteria E ammonia-lyase activity hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic PJD2_k127_1918765_12 459349.CLOAM0984 3.513e-16 94.0 COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25 PJD2_k127_1918765_4 926550.CLDAP_04870 3.947e-104 373.0 COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi 200795|Chloroflexi G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH PJD2_k127_1918765_3 880073.Calab_3349 4.542e-157 514.0 COG0457@1|root,COG0457@2|Bacteria 880073.Calab_3349|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - PJD2_k127_1918765_7 416591.Tlet_1672 6.918e-39 164.0 COG1649@1|root,COG1649@2|Bacteria,2GCSB@200918|Thermotogae 200918|Thermotogae S Glycosyl hydrolase-like 10 - - - - - - - - - - - - GHL10 PJD2_k127_1918765_9 665571.STHERM_c05220 7.434e-28 122.0 COG0203@1|root,COG0203@2|Bacteria,2J841@203691|Spirochaetes 203691|Spirochaetes J Ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 PJD2_k127_1918765_8 1191523.MROS_0189 2.579e-29 120.0 COG0202@1|root,COG0202@2|Bacteria 2|Bacteria K RNA polymerase activity rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L PJD2_k127_1919052_4 1125863.JAFN01000001_gene2261 3.083e-48 186.0 COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria 28221|Deltaproteobacteria T PFAM ATP-binding region, ATPase domain protein - - 2.7.13.3 ko:K07709 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_9 PJD2_k127_1919052_0 1232410.KI421428_gene1054 8.57e-132 436.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domains REC, sigma54 interaction, HTH8 - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_1919052_6 765952.PUV_11340 1.79e-06 59.0 COG2204@1|root,COG2204@2|Bacteria,2JFQI@204428|Chlamydiae 204428|Chlamydiae T Sigma-54 dependent response regulator atoC - - ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_1919052_7 1162668.LFE_0266 9.998e-06 57.0 COG2204@1|root,COG2204@2|Bacteria,3J0FP@40117|Nitrospirae 40117|Nitrospirae T Bacterial regulatory protein, Fis family - - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_1919052_1 880073.Calab_3385 3.817e-104 356.0 COG2204@1|root,COG2204@2|Bacteria,2NQDH@2323|unclassified Bacteria 2|Bacteria T Sigma-54 interaction domain fhlA - - ko:K03413,ko:K13589 ko02020,ko02030,ko04112,map02020,map02030,map04112 M00506,M00512 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_1919052_3 945713.IALB_2930 4.841e-56 210.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - - PJD2_k127_1919052_2 880073.Calab_3649 1.457e-97 342.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2NP1D@2323|unclassified Bacteria 2|Bacteria M Transglycosylase SLT domain CP_0155 - - ko:K08307,ko:K12204 - - - - ko00000,ko01000,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 - - LysM,SLT,T4SS_TraI PJD2_k127_1919052_5 1123371.ATXH01000041_gene685 9.7e-40 165.0 COG2199@1|root,COG3706@2|Bacteria,2GHY7@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF PJD2_k127_1924447_0 697281.Mahau_2342 3.654e-32 143.0 COG0463@1|root,COG2152@1|root,COG0463@2|Bacteria,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,42FMD@68295|Thermoanaerobacterales 186801|Clostridia G PFAM glycosidase related protein - - - - - - - - - - - - Glyco_hydro_130 PJD2_k127_1927873_0 1026882.MAMP_01069 0.0 1097.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales 72273|Thiotrichales E Vitamin B12 dependent methionine synthase, activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans PJD2_k127_1927873_7 401526.TcarDRAFT_1339 8.276e-17 91.0 COG1560@1|root,COG1560@2|Bacteria,1TT7A@1239|Firmicutes,4H33V@909932|Negativicutes 909932|Negativicutes M Lipid A biosynthesis - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans PJD2_k127_1927873_4 497964.CfE428DRAFT_4728 2.373e-49 187.0 COG0463@1|root,COG0463@2|Bacteria,46UW3@74201|Verrucomicrobia 74201|Verrucomicrobia M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 PJD2_k127_1927873_2 1158318.ATXC01000001_gene1391 1.137e-63 226.0 COG0496@1|root,COG0496@2|Bacteria,2G3WU@200783|Aquificae 200783|Aquificae S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE PJD2_k127_1927873_3 667014.Thein_1148 7.068e-58 210.0 COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT PJD2_k127_1927873_5 1094980.Mpsy_1210 2.743e-42 161.0 COG2426@1|root,arCOG01330@2157|Archaea,2XZ2Y@28890|Euryarchaeota,2NAQX@224756|Methanomicrobia 224756|Methanomicrobia S Putative small multi-drug export protein - - - - - - - - - - - - Sm_multidrug_ex PJD2_k127_1927873_1 891968.Anamo_0432 4.553e-66 237.0 COG0568@1|root,COG0568@2|Bacteria,3TACS@508458|Synergistetes 508458|Synergistetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 PJD2_k127_1927873_6 290397.Adeh_0751 3.193e-30 121.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,2Z0FU@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran PJD2_k127_1928982_4 1379698.RBG1_1C00001G1177 3.273e-26 113.0 COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria 2|Bacteria K helix_turn_helix, mercury resistance ycgE - - ko:K19591,ko:K22491 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR_1 PJD2_k127_1928982_1 1191523.MROS_1831 2.198e-101 350.0 COG0240@1|root,COG0240@2|Bacteria 2|Bacteria I glycerol-3-phosphate dehydrogenase [NAD(P)+] activity gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N PJD2_k127_1928982_3 880073.Calab_3206 5.413e-37 158.0 COG0344@1|root,COG0344@2|Bacteria,2NPME@2323|unclassified Bacteria 2|Bacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf PJD2_k127_1928982_0 479434.Sthe_1284 5.075e-117 391.0 COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi,27XGH@189775|Thermomicrobia 189775|Thermomicrobia S GTPase that plays an essential role in the late steps of ribosome biogenesis - - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 PJD2_k127_1928982_2 1120985.AUMI01000015_gene1514 2.118e-79 281.0 COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,4H1YQ@909932|Negativicutes 909932|Negativicutes C FeS-containing Cyanobacterial-specific oxidoreductase - - - - - - - - - - - - DUF512 PJD2_k127_1928982_7 1499967.BAYZ01000115_gene2931 9.597e-05 53.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria 2|Bacteria S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_16,TPR_7,TPR_8 PJD2_k127_1928982_5 321955.AAGP01000047_gene3702 2.453e-16 83.0 COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4F92W@85019|Brevibacteriaceae 201174|Actinobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT PJD2_k127_1947112_2 1191523.MROS_0956 1.421e-26 123.0 28PR2@1|root,2ZCCZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_1947112_3 1499967.BAYZ01000105_gene3517 1.567e-19 102.0 COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - ChitinaseA_N,Lipase_GDSL_2 PJD2_k127_1947112_0 1191523.MROS_1891 1.235e-198 655.0 COG0729@1|root,COG0823@1|root,COG0729@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins treP - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,PD40 PJD2_k127_1947112_1 1333523.L593_10880 5.708e-41 172.0 COG0419@1|root,arCOG00368@2157|Archaea,2XXF9@28890|Euryarchaeota,23VY1@183963|Halobacteria 183963|Halobacteria L AAA domain - - - - - - - - - - - - AAA_27 PJD2_k127_1957339_0 861299.J421_2471 2.997e-183 583.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1ZTEZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes H B12 binding domain - - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans PJD2_k127_1957339_1 987059.RBXJA2T_11957 2.515e-100 351.0 COG3386@1|root,COG3386@2|Bacteria,1NS83@1224|Proteobacteria,2W1T0@28216|Betaproteobacteria 28216|Betaproteobacteria G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - PJD2_k127_1957339_3 518766.Rmar_1071 8.163e-11 75.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 1.14.18.1 ko:K00505 ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916 M00042 R00731,R02078,R02363,R02383,R04693,R04884 RC00046,RC00150,RC00180 ko00000,ko00001,ko00002,ko01000 - - - BNR,FlgD_ig,Peptidase_S74,Tyrosinase PJD2_k127_1957339_2 314285.KT71_17271 3.091e-44 174.0 COG1404@1|root,COG1404@2|Bacteria,1PE2Y@1224|Proteobacteria,1SQ8B@1236|Gammaproteobacteria,1JBCF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Subtilase family - - - - - - - - - - - - Peptidase_S8 PJD2_k127_1959329_3 1379270.AUXF01000003_gene3415 7.797e-88 304.0 COG2273@1|root,COG2273@2|Bacteria 2|Bacteria G xyloglucan:xyloglucosyl transferase activity - - 3.2.1.73 ko:K01216,ko:K07004 - - - - ko00000,ko01000 - - - CBM_6,DUF4971,F5_F8_type_C,Glyco_hydro_16,HemolysinCabind,PA14,Trypsin PJD2_k127_1959329_2 1379270.AUXF01000003_gene3413 3.051e-88 300.0 COG2273@1|root,COG2273@2|Bacteria,1ZUUV@142182|Gemmatimonadetes 142182|Gemmatimonadetes G Glycosyl hydrolases family 16 - - - - - - - - - - - - Glyco_hydro_16 PJD2_k127_1959329_0 1379270.AUXF01000003_gene3409 0.0 1264.0 COG3250@1|root,COG3250@2|Bacteria 2|Bacteria G beta-galactosidase activity - - 3.2.1.89 ko:K01224 - - - - ko00000,ko01000 - - - Big_4,F5_F8_type_C,Glyco_hydro_2_C,Glyco_hydro_53 PJD2_k127_1959329_1 215803.DB30_3124 5.02e-195 618.0 COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria,2YU29@29|Myxococcales 28221|Deltaproteobacteria G Glycosyl hydrolase family 1 - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 PJD2_k127_1959329_4 935836.JAEL01000084_gene766 6.556e-40 167.0 COG2273@1|root,COG2273@2|Bacteria,1UA30@1239|Firmicutes,4IKCF@91061|Bacilli,1ZGF5@1386|Bacillus 91061|Bacilli G Hydrolase Family 16 - - - - - - - - - - - - Glyco_hydro_16 PJD2_k127_1959329_5 880073.Calab_2214 2.7e-17 96.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - ko:K09800 - - - - ko00000,ko02000 - - - - PJD2_k127_1959329_7 1121428.DESHY_160183___1 6.148e-07 62.0 2A9F7@1|root,30YKP@2|Bacteria,1UFJD@1239|Firmicutes,24GQF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - PJD2_k127_1959329_6 880073.Calab_2081 7.301e-16 91.0 COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria 2|Bacteria P LVIVD repeat - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - LVIVD PJD2_k127_1972113_2 765420.OSCT_2114 5.019e-94 325.0 COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia 32061|Chloroflexia Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS PJD2_k127_1972113_12 1379270.AUXF01000004_gene3354 3.442e-10 63.0 COG0730@1|root,COG0730@2|Bacteria,1ZU67@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE PJD2_k127_1972113_9 28229.ND2E_1921 8.633e-51 203.0 2C2F5@1|root,30VYX@2|Bacteria,1MZFF@1224|Proteobacteria,1SB97@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_1972113_4 1313304.CALK_0753 4.304e-86 290.0 COG1136@1|root,COG1136@2|Bacteria 2|Bacteria V lipoprotein transporter activity - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran PJD2_k127_1972113_5 247633.GP2143_17191 8.163e-84 292.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1S1FA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD PJD2_k127_1972113_3 1123228.AUIH01000003_gene918 1.907e-89 310.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1RXRJ@1236|Gammaproteobacteria,1XPVP@135619|Oceanospirillales 135619|Oceanospirillales M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD PJD2_k127_1972113_6 28229.ND2E_1925 3.485e-65 231.0 COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,1S5NE@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like PJD2_k127_1972113_0 861299.J421_3506 2.377e-108 364.0 COG2262@1|root,COG2262@2|Bacteria,1ZSYM@142182|Gemmatimonadetes 142182|Gemmatimonadetes S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 PJD2_k127_1972113_11 696747.NIES39_E02690 1.23e-10 74.0 COG1807@1|root,COG1807@2|Bacteria,1GR6P@1117|Cyanobacteria,1HAH3@1150|Oscillatoriales 1117|Cyanobacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - PJD2_k127_1972113_10 886293.Sinac_6080 3.366e-24 113.0 COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnA - 4.2.1.151 ko:K11782 ko00130,ko01110,map00130,map01110 - R10666 RC03232 ko00000,ko00001,ko01000 - - - VitK2_biosynth PJD2_k127_1972113_1 1267535.KB906767_gene5022 3.769e-103 347.0 COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia 204432|Acidobacteriia E Arginase family - - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase PJD2_k127_1972113_7 266117.Rxyl_2425 2.015e-62 224.0 COG1515@1|root,COG1515@2|Bacteria,2GJEZ@201174|Actinobacteria 201174|Actinobacteria L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA nfi - 3.1.21.7 ko:K05982 - - - - ko00000,ko01000,ko03400 - - - Endonuclease_5 PJD2_k127_1972113_8 237368.SCABRO_01139 7.298e-61 223.0 COG0618@1|root,COG0618@2|Bacteria,2IYQ0@203682|Planctomycetes 203682|Planctomycetes S phosphoesterase RecJ domain protein - - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 PJD2_k127_1978358_2 518766.Rmar_2753 1.857e-47 175.0 COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1FIKZ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 PJD2_k127_1978358_0 1379698.RBG1_1C00001G0884 8.967e-95 325.0 COG2182@1|root,COG2182@2|Bacteria 2|Bacteria G maltose binding - - - ko:K02027,ko:K17329 ko02010,map02010 M00207,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.33 - - SBP_bac_1,SBP_bac_8 PJD2_k127_1978358_1 443254.Marpi_1019 3.575e-66 245.0 COG1175@1|root,COG1175@2|Bacteria,2GC8J@200918|Thermotogae 200918|Thermotogae P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02025,ko:K17242 ko02010,map02010 M00207,M00600 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.39 - - BPD_transp_1 PJD2_k127_1984724_0 1168034.FH5T_19015 1.02e-118 398.0 COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes 976|Bacteroidetes C oxidoreductase - - - - - - - - - - - - - PJD2_k127_1984724_2 237368.SCABRO_04028 4.023e-29 126.0 COG0644@1|root,COG0664@1|root,COG0644@2|Bacteria,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding prnA - 1.14.19.9 ko:K07058,ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_5,Trp_halogenase,cNMP_binding PJD2_k127_1984724_1 439235.Dalk_1526 3.958e-37 146.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales 28221|Deltaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12 PJD2_k127_1992057_1 1122604.JONR01000033_gene34 9.909e-62 220.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales 135614|Xanthomonadales KT LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg PJD2_k127_1992057_2 382464.ABSI01000011_gene2813 3.155e-54 205.0 COG2972@1|root,COG2972@2|Bacteria,46TY3@74201|Verrucomicrobia,2IVUC@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Histidine kinase - - - - - - - - - - - - His_kinase PJD2_k127_1992057_3 1191523.MROS_0247 4.123e-47 172.0 COG3304@1|root,COG3304@2|Bacteria 2|Bacteria S Inner membrane component domain yccF - - - - - - - - - - - YccF PJD2_k127_1992057_0 330214.NIDE3598 6.678e-139 448.0 COG0702@1|root,COG0702@2|Bacteria 2|Bacteria GM epimerase - - - - - - - - - - - - NmrA PJD2_k127_1996586_0 945713.IALB_0538 6.153e-133 433.0 COG0635@1|root,COG0635@2|Bacteria 2|Bacteria H coproporphyrinogen oxidase activity hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 HemN_C,Radical_SAM PJD2_k127_1996586_1 945713.IALB_0230 4.03e-57 209.0 COG1232@1|root,COG1232@2|Bacteria 2|Bacteria H protoporphyrinogen oxidase activity hemG - 1.14.19.9,1.3.3.15,1.3.3.4 ko:K00231,ko:K14266 ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130 M00121,M00789,M00790 R03222,R04178,R09570 RC00885,RC00949 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase PJD2_k127_2014281_2 864051.BurJ1DRAFT_2685 6.339e-117 392.0 COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome b/b6/petB - - - - - - - - - - - - Ni_hydr_CYTB PJD2_k127_2014281_3 314285.KT71_18436 3.067e-65 242.0 COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,1RSIU@1236|Gammaproteobacteria,1JBRF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 ydhU GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08354 ko00920,ko01120,map00920,map01120 - R10149 RC02823 ko00000,ko00001,ko02000 5.A.3.5 - - Cytochrome_C7,Ni_hydr_CYTB PJD2_k127_2014281_5 864051.BurJ1DRAFT_2686 1.677e-47 176.0 COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,2VXAQ@28216|Betaproteobacteria,1KP4P@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp PJD2_k127_2014281_6 314285.KT71_18446 4.059e-30 122.0 COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1J96D@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Rhodanese,Sulf_transp PJD2_k127_2014281_9 314285.KT71_18446 6.194e-15 77.0 COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1J96D@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Rhodanese,Sulf_transp PJD2_k127_2014281_7 314285.KT71_18446 2.222e-21 102.0 COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1J96D@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Rhodanese,Sulf_transp PJD2_k127_2014281_8 1506583.JQJY01000005_gene2042 3.267e-15 84.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia,2NWCZ@237|Flavobacterium 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 PJD2_k127_2014281_1 1121930.AQXG01000001_gene1202 8.534e-179 601.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran PJD2_k127_2014281_0 1211114.ALIP01000164_gene2781 2.463e-239 786.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3PQ@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mdtB - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran PJD2_k127_2014281_4 880073.Calab_1194 2.637e-48 185.0 COG0845@1|root,COG0845@2|Bacteria,2NR7K@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 PJD2_k127_2035921_2 710696.Intca_0558 1.835e-08 55.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - GerE PJD2_k127_2035921_0 1123267.JONN01000001_gene1706 3.604e-51 193.0 COG0823@1|root,COG0823@2|Bacteria,1MZ1T@1224|Proteobacteria,2UKB8@28211|Alphaproteobacteria,2K99E@204457|Sphingomonadales 204457|Sphingomonadales U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 PJD2_k127_2035921_1 944435.AXAJ01000005_gene3484 6.146e-18 85.0 COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2VM0D@28216|Betaproteobacteria,1K48Y@119060|Burkholderiaceae 28216|Betaproteobacteria I Belongs to the thiolase family - - 2.3.1.16 ko:K00632,ko:K07550 ko00071,ko00280,ko00281,ko00362,ko00592,ko00623,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,ko01220,map00071,map00280,map00281,map00362,map00592,map00623,map00642,map01100,map01110,map01120,map01130,map01212,map01220 M00087,M00113,M00418 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R05587,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01428,RC01702,RC02728,RC02898,RC02904,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N PJD2_k127_2049320_2 929506.CbC4_1017 1.141e-09 64.0 COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,36KNM@31979|Clostridiaceae 186801|Clostridia T Belongs to the anti-sigma-factor antagonist family spoIIAA - - ko:K06378 - - - - ko00000 - - - STAS PJD2_k127_2049320_0 1356852.N008_00760 7.548e-283 887.0 COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,47KWW@768503|Cytophagia 976|Bacteroidetes E PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N PJD2_k127_2049320_1 1121015.N789_12880 2.991e-43 161.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1X5Z3@135614|Xanthomonadales 135614|Xanthomonadales S Nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ yajQ - - ko:K09767 - - - - ko00000 - - - DUF520 PJD2_k127_2056281_3 1123392.AQWL01000002_gene2110 5.465e-05 50.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,1KRA8@119069|Hydrogenophilales 119069|Hydrogenophilales U SRP54-type protein, helical bundle domain - - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N PJD2_k127_2056281_0 517418.Ctha_0007 1.718e-145 504.0 COG1196@1|root,COG1196@2|Bacteria,1FDPC@1090|Chlorobi 1090|Chlorobi D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge PJD2_k127_2056281_1 1121468.AUBR01000016_gene2303 1.639e-91 323.0 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,42F61@68295|Thermoanaerobacterales 186801|Clostridia J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA - 2.9.1.1,4.3.1.29 ko:K01042,ko:K17468 ko00030,ko00450,ko00970,ko01120,map00030,map00450,map00970,map01120 - R08219,R10408 RC00544,RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA PJD2_k127_2056281_2 1196029.ALIM01000014_gene2836 6.692e-24 113.0 COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus 91061|Bacilli M COG3103 SH3 domain protein lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 PJD2_k127_206355_6 1382306.JNIM01000001_gene2893 2.081e-16 85.0 COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi 200795|Chloroflexi M PFAM Mandelate racemase muconate lactonizing protein - - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N PJD2_k127_206355_4 877420.ATVW01000006_gene603 4.838e-18 89.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,27IWD@186928|unclassified Lachnospiraceae 186801|Clostridia S Transporter associated domain - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 PJD2_k127_206355_3 1449126.JQKL01000073_gene3045 4.85e-21 100.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,268U9@186813|unclassified Clostridiales 186801|Clostridia S Transporter associated domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 PJD2_k127_206355_0 1443122.Z958_00155 3.545e-72 259.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae 186801|Clostridia S CBS domain - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 PJD2_k127_206355_7 1379698.RBG1_1C00001G0502 9.147e-14 81.0 COG1729@1|root,COG1729@2|Bacteria,2NQ0B@2323|unclassified Bacteria 2|Bacteria S Outer membrane lipoprotein cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri PJD2_k127_206355_2 1379698.RBG1_1C00001G0501 2.315e-36 144.0 COG2885@1|root,COG2885@2|Bacteria,2NPMV@2323|unclassified Bacteria 2|Bacteria M OmpA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA PJD2_k127_206355_1 443144.GM21_3582 7.723e-67 243.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N PJD2_k127_206355_5 1379698.RBG1_1C00001G0499 6.158e-17 86.0 COG0810@1|root,COG0810@2|Bacteria,2NQ3G@2323|unclassified Bacteria 2|Bacteria M TonB C terminal - - - ko:K03646,ko:K03832 - - - - ko00000,ko02000 2.C.1.1,2.C.1.2 - - CarbopepD_reg_2,TonB_2,TonB_C PJD2_k127_2065770_1 240016.ABIZ01000001_gene5365 6.8e-63 230.0 COG1524@1|root,COG1524@2|Bacteria,46XAN@74201|Verrucomicrobia,2IV7D@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_2065770_3 1227497.C491_10704 5.353e-12 78.0 COG2244@1|root,arCOG02209@2157|Archaea,2XVSG@28890|Euryarchaeota,23TS7@183963|Halobacteria 183963|Halobacteria S Membrane protein involved in the export of O-antigen and teichoic acid - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C PJD2_k127_2065770_0 1340493.JNIF01000003_gene2680 1.013e-73 254.0 COG1215@1|root,COG1215@2|Bacteria,3Y5K6@57723|Acidobacteria 57723|Acidobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 PJD2_k127_2065770_2 266117.Rxyl_0689 1.273e-35 151.0 COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4CT94@84995|Rubrobacteria 84995|Rubrobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 PJD2_k127_2065770_4 309801.trd_0452 6.547e-08 64.0 COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi,27XSJ@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 PJD2_k127_2076886_7 335543.Sfum_0219 2.05e-29 135.0 COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2MRX9@213462|Syntrophobacterales 28221|Deltaproteobacteria O Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_2076886_4 717605.Theco_3902 8.426e-62 223.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,26SEN@186822|Paenibacillaceae 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind PJD2_k127_2076886_2 1379698.RBG1_1C00001G0798 1.862e-128 444.0 COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria 2|Bacteria E aminopeptidase pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - HEAT_2,Peptidase_M1 PJD2_k127_2076886_14 82654.Pse7367_1630 0.0007822 51.0 COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1G03V@1117|Cyanobacteria,1H7B2@1150|Oscillatoriales 1117|Cyanobacteria CE PFAM peptidase M1, membrane alanine aminopeptidase pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,HEAT_2,Peptidase_M1 PJD2_k127_2076886_10 266117.Rxyl_2877 4.911e-22 102.0 COG1246@1|root,COG1246@2|Bacteria 2|Bacteria E Belongs to the acetyltransferase family. ArgA subfamily ywlB - 2.3.1.1 ko:K00619 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C PJD2_k127_2076886_12 1437425.CSEC_0646 1.449e-10 66.0 2EQQP@1|root,33IAK@2|Bacteria,2JGJU@204428|Chlamydiae 204428|Chlamydiae S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 PJD2_k127_2076886_13 1379698.RBG1_1C00001G0145 1.065e-09 66.0 2EPKR@1|root,33H7C@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_2076886_3 1379698.RBG1_1C00001G0146 1.206e-72 253.0 COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria 2|Bacteria C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A PJD2_k127_2076886_9 1379698.RBG1_1C00001G0147 6.774e-23 101.0 COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria 2|Bacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C PJD2_k127_2076886_6 1379698.RBG1_1C00001G0148 1.126e-31 129.0 COG0711@1|root,COG0711@2|Bacteria,2NQ34@2323|unclassified Bacteria 2|Bacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B PJD2_k127_2076886_8 477974.Daud_2140 8.905e-28 121.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,261U6@186807|Peptococcaceae 186801|Clostridia C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP PJD2_k127_2076886_0 1379698.RBG1_1C00001G0150 1.32e-228 717.0 COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N PJD2_k127_2076886_5 1379698.RBG1_1C00001G0152 1.202e-57 211.0 COG0224@1|root,COG0224@2|Bacteria,2NP76@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138 ATP-synt PJD2_k127_2076886_1 1379698.RBG1_1C00001G0153 3.097e-228 730.0 COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N PJD2_k127_2076886_11 264732.Moth_2377 8.377e-17 83.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,42H8Y@68295|Thermoanaerobacterales 186801|Clostridia C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iHN637.CLJU_RS01195 ATP-synt_DE,ATP-synt_DE_N PJD2_k127_2089236_5 880073.Calab_3717 2.59e-44 167.0 COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria 2|Bacteria H Flavin containing amine oxidoreductase hemG - 1.14.19.9,1.3.3.15,1.3.3.4 ko:K00231,ko:K14266 ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130 M00121,M00789,M00790 R03222,R04178,R09570 RC00885,RC00949 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase PJD2_k127_2089236_4 344747.PM8797T_30781 8.834e-97 321.0 COG0605@1|root,COG0605@2|Bacteria,2IX16@203682|Planctomycetes 203682|Planctomycetes C Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N PJD2_k127_2089236_6 330214.NIDE0156 4.665e-42 157.0 COG2154@1|root,COG2154@2|Bacteria 2|Bacteria H pterin-4-alpha-carbinolamine dehydratase phhB GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a PJD2_k127_2089236_7 391625.PPSIR1_41114 5.368e-23 106.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42U5E@68525|delta/epsilon subdivisions,2WSV3@28221|Deltaproteobacteria 28221|Deltaproteobacteria S thioesterase - - 3.1.2.28 ko:K07107,ko:K12073 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 - - - 4HBT PJD2_k127_2089236_3 797209.ZOD2009_03090 5.724e-112 371.0 COG0604@1|root,arCOG01458@2157|Archaea,2XU0Q@28890|Euryarchaeota,23SPC@183963|Halobacteria 183963|Halobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases qor1 - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N PJD2_k127_2089236_0 1254432.SCE1572_07650 2.25e-195 623.0 COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase - - 4.1.2.44 ko:K15513 ko00362,map00362 - R09556 RC03426 ko00000,ko00001,ko01000 - - - ECH_1 PJD2_k127_2089236_1 502025.Hoch_5225 1.521e-190 605.0 COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,437U1@68525|delta/epsilon subdivisions,2X33K@28221|Deltaproteobacteria,2YU2K@29|Myxococcales 28221|Deltaproteobacteria S benzoyl-CoA oxygenase - - 1.14.13.208 ko:K15512 ko00362,map00362 - R09555 RC01739 ko00000,ko00001,ko01000 - - - - PJD2_k127_2089236_2 1379698.RBG1_1C00001G0805 1.004e-167 541.0 COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria 2|Bacteria C Belongs to the aldehyde dehydrogenase family aldH - 1.2.1.3 ko:K00128,ko:K00138 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh PJD2_k127_2089236_8 748247.AZKH_3200 4.721e-06 57.0 COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria,2KWVW@206389|Rhodocyclales 206389|Rhodocyclales M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C PJD2_k127_2138663_9 483219.LILAB_17070 0.0004277 49.0 COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,438GF@68525|delta/epsilon subdivisions,2X3RA@28221|Deltaproteobacteria,2YWWZ@29|Myxococcales 28221|Deltaproteobacteria M Bacterial Ig-like domain (group 1) - - - - - - - - - - - - Big_1,LTD PJD2_k127_2138663_0 404589.Anae109_0473 5.28e-117 385.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2YUI6@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Thioredoxin PJD2_k127_2138663_6 1120951.AUBG01000006_gene482 2.067e-17 94.0 COG3137@1|root,COG3137@2|Bacteria,4NJH6@976|Bacteroidetes,1I1BJ@117743|Flavobacteriia 976|Bacteroidetes M Protein of unknown function, DUF481 - - - - - - - - - - - - DUF481 PJD2_k127_2138663_3 103690.17134426 1.455e-58 209.0 COG0302@1|root,COG0302@2|Bacteria,1G1K8@1117|Cyanobacteria,1HIXJ@1161|Nostocales 1117|Cyanobacteria H PFAM GTP cyclohydrolase I folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.folE,iJN678.folE GTP_cyclohydroI PJD2_k127_2138663_1 644966.Tmar_1229 6.916e-112 375.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WCZD@538999|Clostridiales incertae sedis 186801|Clostridia E Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 PJD2_k127_2138663_2 671143.DAMO_1182 7.708e-97 320.0 COG0717@1|root,COG0717@2|Bacteria,2NQ5G@2323|unclassified Bacteria 2|Bacteria F Belongs to the dCTP deaminase family dcd GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase PJD2_k127_2138663_8 309800.C498_11131 0.0001843 46.0 arCOG02989@1|root,arCOG02989@2157|Archaea,2Y00B@28890|Euryarchaeota,23XHN@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - PJD2_k127_2138663_5 926550.CLDAP_11900 1.004e-20 104.0 COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi 2|Bacteria O Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 PJD2_k127_2138663_4 269799.Gmet_1981 1.14e-33 138.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,42RSE@68525|delta/epsilon subdivisions,2WP0K@28221|Deltaproteobacteria,43SGX@69541|Desulfuromonadales 28221|Deltaproteobacteria S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC PJD2_k127_214619_2 1440053.JOEI01000018_gene252 1.942e-24 108.0 COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria 201174|Actinobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 PJD2_k127_214619_4 945713.IALB_0474 5.062e-19 92.0 COG1734@1|root,COG1734@2|Bacteria 2|Bacteria T zinc ion binding dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR PJD2_k127_214619_1 398512.JQKC01000015_gene4608 1.442e-26 121.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WJA4@541000|Ruminococcaceae 186801|Clostridia MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 PJD2_k127_214619_0 1382304.JNIL01000001_gene693 5.431e-78 273.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,2782F@186823|Alicyclobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 PJD2_k127_214619_3 1379698.RBG1_1C00001G0632 4.983e-24 107.0 COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria 2|Bacteria T STAS domain rsbV - - ko:K04749 - - - - ko00000,ko03021 - - - STAS,STAS_2 PJD2_k127_214619_5 378806.STAUR_7590 9.157e-14 77.0 COG2172@1|root,COG2172@2|Bacteria 2|Bacteria T sigma factor antagonist activity - - 2.7.11.1 ko:K04757,ko:K17752 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2,SpoIIE PJD2_k127_217221_1 880073.Calab_0041 2.365e-08 59.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 1.14.18.1 ko:K00505 ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916 M00042 R00731,R02078,R02363,R02383,R04693,R04884 RC00046,RC00150,RC00180 ko00000,ko00001,ko00002,ko01000 - - - BNR,FlgD_ig,Peptidase_S74,Tyrosinase PJD2_k127_217221_0 870187.Thini_0382 1.631e-26 112.0 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,463F1@72273|Thiotrichales 72273|Thiotrichales L PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 PJD2_k127_2197957_1 521045.Kole_0873 2.066e-67 238.0 COG0395@1|root,COG0395@2|Bacteria,2GCNE@200918|Thermotogae 200918|Thermotogae P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 PJD2_k127_2197957_0 1268072.PSAB_07700 4.761e-83 290.0 COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,4HAYA@91061|Bacilli,26SDJ@186822|Paenibacillaceae 91061|Bacilli O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK PJD2_k127_2197957_3 1379698.RBG1_1C00001G0322 7.141e-52 209.0 COG2385@1|root,COG2385@2|Bacteria,2NPRR@2323|unclassified Bacteria 2|Bacteria D Stage II sporulation protein - - - ko:K06381 - - - - ko00000 - - - SpoIID PJD2_k127_2197957_2 1280663.ATVR01000002_gene331 7.19e-53 208.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,4BX6E@830|Butyrivibrio 186801|Clostridia G Glycosyl hydrolase family 3 N terminal domain - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3,Glyco_hydro_3_C PJD2_k127_2216138_5 1499967.BAYZ01000054_gene4817 1.768e-35 142.0 COG0601@1|root,COG0601@2|Bacteria 2|Bacteria P nitrogen compound transport appB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 PJD2_k127_2216138_1 649747.HMPREF0083_01450 2.236e-167 539.0 COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,26RUP@186822|Paenibacillaceae 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P PJD2_k127_2216138_2 290315.Clim_0621 9.89e-127 419.0 COG0403@1|root,COG0403@2|Bacteria,1FDMI@1090|Chlorobi 1090|Chlorobi F The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P PJD2_k127_2216138_4 1237149.C900_04703 1.34e-39 152.0 COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,47QD7@768503|Cytophagia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H PJD2_k127_2216138_3 485913.Krac_8783 2.524e-108 366.0 COG0404@1|root,COG0404@2|Bacteria,2G5VA@200795|Chloroflexi 200795|Chloroflexi E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C PJD2_k127_2216138_0 1379698.RBG1_1C00001G0659 0.0 1157.0 COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria 2|Bacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran PJD2_k127_2216138_6 861299.J421_1638 5.238e-28 119.0 COG1247@1|root,COG1247@2|Bacteria 2|Bacteria M phosphinothricin N-acetyltransferase activity pat - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 PJD2_k127_2220371_3 349124.Hhal_0066 2.843e-88 308.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1141@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1141@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1WX9H@135613|Chromatiales 135613|Chromatiales C pyruvate flavodoxin ferredoxin oxidoreductase - - 1.2.7.1 ko:K00169,ko:K03737 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034,R10866 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C PJD2_k127_2220371_2 765910.MARPU_10745 9.766e-93 313.0 COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria,1WWC5@135613|Chromatiales 135613|Chromatiales C Fe-S cluster - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4 PJD2_k127_2220371_4 1049564.TevJSym_bb00030 5.864e-72 272.0 COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria 1224|Proteobacteria C 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - TPP_enzyme_C PJD2_k127_2220371_1 1049564.TevJSym_bb00040 3.101e-108 365.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit korB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C PJD2_k127_2220371_0 1049564.TevJSym_bb00050 2.124e-236 753.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N PJD2_k127_2220371_5 146922.JOFU01000017_gene3538 2.756e-10 63.0 COG1141@1|root,COG1141@2|Bacteria 2|Bacteria C electron transfer activity - - - ko:K05337 - - - - ko00000 - - - Fer4_13,Fer4_15 PJD2_k127_2235453_2 1123242.JH636435_gene1286 1.158e-50 192.0 COG1131@1|root,COG1131@2|Bacteria,2IY79@203682|Planctomycetes 203682|Planctomycetes V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran PJD2_k127_2235453_5 498211.CJA_0601 3.223e-21 101.0 COG1725@1|root,COG1725@2|Bacteria,1N23D@1224|Proteobacteria,1S9NK@1236|Gammaproteobacteria,1FHGJ@10|Cellvibrio 1236|Gammaproteobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR PJD2_k127_2235453_4 1194165.CAJF01000022_gene3110 5.451e-28 122.0 COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4FNZB@85023|Microbacteriaceae 201174|Actinobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 PJD2_k127_2235453_3 243231.GSU1562 4.492e-43 160.0 COG0011@1|root,COG0011@2|Bacteria,1N2GU@1224|Proteobacteria,42UPF@68525|delta/epsilon subdivisions,2WR94@28221|Deltaproteobacteria,43W2X@69541|Desulfuromonadales 28221|Deltaproteobacteria S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP PJD2_k127_2235453_1 1232410.KI421415_gene2976 7.924e-79 269.0 COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria,43SVV@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - Peptidase_C39,Peptidase_C39_2 PJD2_k127_2235453_0 1232410.KI421415_gene2975 5.68e-175 559.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria,43UK8@69541|Desulfuromonadales 28221|Deltaproteobacteria HJ RimK-like ATPgrasp N-terminal domain - - - - - - - - - - - - Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK PJD2_k127_2279065_1 926550.CLDAP_28720 1.21e-13 76.0 COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi 200795|Chloroflexi S PFAM LmbE family protein - - 3.5.1.115 ko:K18455 - - - - ko00000,ko01000 - - - PIG-L PJD2_k127_2279065_0 550540.Fbal_0699 5.236e-121 407.0 COG0265@1|root,COG3591@1|root,COG0265@2|Bacteria,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,1RRGG@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Peptidase S46 - - - - - - - - - - - - Peptidase_S46 PJD2_k127_2289334_6 314271.RB2654_04259 9.709e-25 110.0 2F607@1|root,33YIP@2|Bacteria,1NYAX@1224|Proteobacteria 1224|Proteobacteria S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - - PJD2_k127_2289334_5 314271.RB2654_04259 1.727e-27 119.0 2F607@1|root,33YIP@2|Bacteria,1NYAX@1224|Proteobacteria 1224|Proteobacteria S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - - PJD2_k127_2289334_2 1379698.RBG1_1C00001G0356 5.713e-104 372.0 COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria 2|Bacteria EG Protein of unknown function (DUF2723) - - - ko:K16928 - M00582 - - ko00000,ko00002,ko02000 3.A.1.33 - - DUF2723,QueT PJD2_k127_2289334_1 1249627.D779_2312 1.544e-204 653.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1WXUN@135613|Chromatiales 135613|Chromatiales P TrkA-C domain - - - - - - - - - - - - CitMHS,TrkA_C PJD2_k127_2289334_0 1121422.AUMW01000026_gene381 7.126e-210 664.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae 186801|Clostridia C Belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8,1.2.1.99 ko:K00130,ko:K00135,ko:K09472,ko:K22187 ko00040,ko00250,ko00260,ko00310,ko00330,ko00350,ko00650,ko00760,ko01100,ko01120,map00040,map00250,map00260,map00310,map00330,map00350,map00650,map00760,map01100,map01120 M00027,M00136,M00555 R00713,R00714,R02401,R02565,R02566,R07417,R07418,R11768 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh PJD2_k127_2289334_3 1232410.KI421418_gene2141 7.107e-63 224.0 COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,42TN0@68525|delta/epsilon subdivisions,2WQ75@28221|Deltaproteobacteria,43UN4@69541|Desulfuromonadales 28221|Deltaproteobacteria S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 PJD2_k127_2289334_8 1205680.CAKO01000006_gene3396 1.577e-05 57.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 PJD2_k127_2289334_4 998088.B565_3169 2.369e-42 164.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1Y4KW@135624|Aeromonadales 135624|Aeromonadales L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated - - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N PJD2_k127_2289334_7 441620.Mpop_3037 5.953e-12 66.0 COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria,1JSU7@119045|Methylobacteriaceae 28211|Alphaproteobacteria L AlkA N-terminal domain - - 3.2.2.21 ko:K01247,ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD PJD2_k127_2309596_4 1184267.A11Q_1223 8.469e-44 163.0 COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2MSPA@213481|Bdellovibrionales,2WM27@28221|Deltaproteobacteria 213481|Bdellovibrionales C Belongs to the heme-copper respiratory oxidase family - - 1.9.3.1 ko:K00404,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1,FixO PJD2_k127_2309596_3 264462.Bd2613 3.165e-46 173.0 COG2010@1|root,COG2010@2|Bacteria,1Q1J4@1224|Proteobacteria,42X3D@68525|delta/epsilon subdivisions,2MT8H@213481|Bdellovibrionales,2WSZH@28221|Deltaproteobacteria 213481|Bdellovibrionales C N-terminal domain of cytochrome oxidase-cbb3, FixP - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N PJD2_k127_2309596_1 264462.Bd2614 1.964e-147 482.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2MSRS@213481|Bdellovibrionales,2WNZJ@28221|Deltaproteobacteria 213481|Bdellovibrionales C 4Fe-4S dicluster domain ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C PJD2_k127_2309596_0 1237149.C900_01007 3.174e-181 596.0 COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia 976|Bacteroidetes S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - CarbopepD_reg_2,DUF3520,VWA,vWF_A PJD2_k127_2309596_5 1313421.JHBV01000014_gene3809 1.437e-15 89.0 2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1IU9B@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4286) - - - - - - - - - - - - DUF4286 PJD2_k127_2309596_2 1123008.KB905694_gene1719 3.142e-56 212.0 COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,2FPEJ@200643|Bacteroidia,22YY7@171551|Porphyromonadaceae 976|Bacteroidetes Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) arsM - 2.1.1.137,2.1.1.79 ko:K00574,ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_31 PJD2_k127_2327696_4 880073.Calab_2377 2.607e-15 89.0 COG1404@1|root,COG3637@1|root,COG1404@2|Bacteria,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety msp3 - - - - - - - - - - - SLH,Surface_Ag_2 PJD2_k127_2327696_3 529818.AMSG_07677T0 1.02e-31 141.0 KOG0379@1|root,KOG4293@1|root,KOG0379@2759|Eukaryota,KOG4293@2759|Eukaryota 2759|Eukaryota U DOMON domain-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0012505,GO:0031410,GO:0031982,GO:0031984,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0097708,GO:0098791 - - - - - - - - - - Cytochrom_B561,Cytochrom_C_asm,DM13,DOMON,Kelch_4 PJD2_k127_2327696_0 56780.SYN_01902 6.752e-183 597.0 COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,42MQ2@68525|delta/epsilon subdivisions,2WM1F@28221|Deltaproteobacteria,2MR0K@213462|Syntrophobacterales 28221|Deltaproteobacteria M Glycosyltransferase Family 4 - - 2.4.1.345 ko:K08256 - - R11702 - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 PJD2_k127_2327696_2 1408473.JHXO01000008_gene2653 1.945e-69 246.0 COG2120@1|root,COG2120@2|Bacteria,4NM6J@976|Bacteroidetes 976|Bacteroidetes S PFAM GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L PJD2_k127_2327696_1 1121918.ARWE01000001_gene3039 4.826e-72 247.0 COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2WWCN@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel PJD2_k127_2330391_6 530564.Psta_1912 2.148e-09 72.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - B_lectin,Inhibitor_I9,Peptidase_S8,SLH PJD2_k127_2330391_7 518766.Rmar_2820 1.054e-06 62.0 COG2374@1|root,COG2374@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Endonuclease_1,Exo_endo_phos,LTD PJD2_k127_2330391_4 530564.Psta_1912 5.493e-12 79.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - B_lectin,Inhibitor_I9,Peptidase_S8,SLH PJD2_k127_2330391_0 761193.Runsl_1910 0.0 1394.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47N7Y@768503|Cytophagia 976|Bacteroidetes QU Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,PD40 PJD2_k127_2330391_1 1047013.AQSP01000126_gene2741 9.535e-304 945.0 COG0339@1|root,COG0339@2|Bacteria,2NP9Q@2323|unclassified Bacteria 2|Bacteria E Peptidase family M3 prlC - 3.4.15.5,3.4.24.70 ko:K01284,ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 PJD2_k127_2330391_2 493475.GARC_5311 1.135e-244 769.0 COG2873@1|root,COG2873@2|Bacteria,1R3QG@1224|Proteobacteria,1RNSA@1236|Gammaproteobacteria,46648@72275|Alteromonadaceae 1236|Gammaproteobacteria E Cys/Met metabolism PLP-dependent enzyme - - - - - - - - - - - - Cys_Met_Meta_PP PJD2_k127_2330391_5 1487923.DP73_10870 4.555e-10 64.0 COG3088@1|root,COG3088@2|Bacteria,1VETA@1239|Firmicutes,24TPT@186801|Clostridia,265EA@186807|Peptococcaceae 186801|Clostridia P subunit of a heme lyase - - - ko:K02200 - - - - ko00000 - - - CcmH PJD2_k127_2330391_3 1038860.AXAP01000004_gene5064 3.337e-21 104.0 COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,2UK9W@28211|Alphaproteobacteria 28211|Alphaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - - PJD2_k127_2339172_5 1521187.JPIM01000004_gene3093 3.614e-08 66.0 COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,374VP@32061|Chloroflexia 32061|Chloroflexia M Lytic transglycosylase catalytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,TPR_16 PJD2_k127_2339172_0 717231.Flexsi_1807 8.383e-186 593.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GEZG@200930|Deferribacteres 200930|Deferribacteres F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase PJD2_k127_2339172_1 1337936.IJ00_04030 2.964e-131 437.0 COG0138@1|root,COG0138@2|Bacteria,1G10K@1117|Cyanobacteria,1HJTV@1161|Nostocales 1117|Cyanobacteria F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.purH AICARFT_IMPCHas,MGS PJD2_k127_2339172_2 479434.Sthe_1292 1.807e-104 347.0 COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia 189775|Thermomicrobia F SAICAR synthetase purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt PJD2_k127_2339172_3 747365.Thena_0622 3.572e-52 192.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,42GE6@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS04225 Formyl_trans_N PJD2_k127_2339172_4 314278.NB231_17023 6.772e-17 94.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1WWQ3@135613|Chromatiales 135613|Chromatiales S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B PJD2_k127_2345014_17 471853.Bcav_2473 7.777e-06 59.0 COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria 201174|Actinobacteria I Diacylglycerol kinase - - - - - - - - - - - - DAGK_cat PJD2_k127_2345014_18 1254432.SCE1572_05885 7.541e-05 53.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WN3N@28221|Deltaproteobacteria,2YVHP@29|Myxococcales 28221|Deltaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin PJD2_k127_2345014_12 945713.IALB_1151 9.659e-42 159.0 COG1418@1|root,COG1418@2|Bacteria 2|Bacteria S mRNA catabolic process - - - ko:K06950,ko:K09163 - - - - ko00000 - - - HD PJD2_k127_2345014_14 378806.STAUR_1528 3.569e-40 167.0 COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales 28221|Deltaproteobacteria E Glycine cleavage T-protein C-terminal barrel domain - - 2.1.2.10 ko:K00605,ko:K06980 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 - - - GCV_T,GCV_T_C PJD2_k127_2345014_15 639030.JHVA01000001_gene3205 7.082e-25 108.0 COG1959@1|root,COG1959@2|Bacteria,3Y4X0@57723|Acidobacteria,2JJEV@204432|Acidobacteriia 204432|Acidobacteriia K Transcriptional regulator - - - - - - - - - - - - Rrf2 PJD2_k127_2345014_2 1267533.KB906741_gene405 1.002e-103 349.0 COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria,2JNCI@204432|Acidobacteriia 204432|Acidobacteriia P Ring hydroxylating alpha subunit (catalytic domain) - - - ko:K00479 - - - - ko00000 - - - Rieske,Ring_hydroxyl_A PJD2_k127_2345014_11 1382306.JNIM01000001_gene2623 3.238e-51 206.0 COG0611@1|root,COG0611@2|Bacteria,2G6SH@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C PJD2_k127_2345014_16 1123501.KB902276_gene1138 6.435e-16 80.0 COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterized conserved protein (DUF2277) MA20_01405 - - - - - - - - - - - DUF2277 PJD2_k127_2345014_0 1279009.ADICEAN_00512 1.532e-215 689.0 COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia 976|Bacteroidetes E Leukotriene A4 hydrolase, C-terminal - - - - - - - - - - - - Leuk-A4-hydro_C,Peptidase_M1 PJD2_k127_2345014_9 1499686.BN1079_02122 2.386e-53 196.0 COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,1S69D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphoesterase - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 PJD2_k127_2345014_6 497964.CfE428DRAFT_2280 6.086e-58 220.0 COG1680@1|root,COG1680@2|Bacteria,46SS8@74201|Verrucomicrobia 74201|Verrucomicrobia V Beta-lactamase - - - - - - - - - - - - Beta-lactamase PJD2_k127_2345014_13 1317122.ATO12_18565 2.097e-40 166.0 COG3391@1|root,COG3391@2|Bacteria,4NSAP@976|Bacteroidetes,1I7PP@117743|Flavobacteriia,2YHS6@290174|Aquimarina 976|Bacteroidetes S amine dehydrogenase activity - - - - - - - - - - - - SGL PJD2_k127_2345014_3 1379270.AUXF01000005_gene519 1.804e-84 295.0 COG4409@1|root,COG4409@2|Bacteria,1ZUBR@142182|Gemmatimonadetes 142182|Gemmatimonadetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - PJD2_k127_2345014_8 595460.RRSWK_01550 1.005e-55 212.0 COG3049@1|root,COG3049@2|Bacteria 2|Bacteria M Linear amide C-N hydrolases, choloylglycine hydrolase family - - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH PJD2_k127_2345014_10 1173028.ANKO01000193_gene5873 7.807e-52 192.0 COG2340@1|root,COG2340@2|Bacteria,1G766@1117|Cyanobacteria,1HHES@1150|Oscillatoriales 1117|Cyanobacteria O Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,PPC PJD2_k127_2345014_1 1144275.COCOR_07393 1.601e-159 523.0 COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,43BRM@68525|delta/epsilon subdivisions,2WM4A@28221|Deltaproteobacteria,2YXHE@29|Myxococcales 28221|Deltaproteobacteria P TrkA-N domain - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger,TrkA_N PJD2_k127_2345014_5 521460.Athe_2203 3.76e-58 211.0 COG0584@1|root,COG0584@2|Bacteria,1V3Z1@1239|Firmicutes,24C71@186801|Clostridia 186801|Clostridia C Glycerophosphodiester phosphodiesterase family protein - - - - - - - - - - - - GDPD PJD2_k127_2345014_7 1267535.KB906767_gene4838 4.057e-56 214.0 COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 PJD2_k127_2345014_4 580332.Slit_1302 8.582e-72 256.0 COG2703@1|root,COG4191@1|root,COG2703@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,44WDU@713636|Nitrosomonadales 28216|Betaproteobacteria PT PFAM ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,Hemerythrin,HisKA,PAS_4 PJD2_k127_2347413_0 1220534.B655_1034 9.836e-76 275.0 COG1032@1|root,arCOG01356@2157|Archaea 2157|Archaea C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - B12-binding,Radical_SAM PJD2_k127_2347413_1 639030.JHVA01000001_gene2457 8.086e-13 75.0 2DEWU@1|root,2ZPJP@2|Bacteria,3Y585@57723|Acidobacteria,2JJN8@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - PJD2_k127_2380887_24 489825.LYNGBM3L_48360 9.268e-46 168.0 COG5505@1|root,COG5505@2|Bacteria,1G9X6@1117|Cyanobacteria 1117|Cyanobacteria S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 PJD2_k127_2380887_4 926550.CLDAP_16270 2.702e-193 616.0 COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria 2|Bacteria K acetyltransferase yhcX - - ko:K11206 - - - - ko00000,ko01000 - - - Acetyltransf_1,CN_hydrolase PJD2_k127_2380887_23 1279009.ADICEAN_00204 1.486e-46 179.0 COG2940@1|root,COG2940@2|Bacteria,4NM5I@976|Bacteroidetes,47WYB@768503|Cytophagia 976|Bacteroidetes S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - - - - - - - - - - SET PJD2_k127_2380887_2 1121918.ARWE01000001_gene2468 2.826e-258 818.0 COG0531@1|root,COG0531@2|Bacteria,1R4IZ@1224|Proteobacteria,42MTQ@68525|delta/epsilon subdivisions,2WK39@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM Amino acid - - - - - - - - - - - - AA_permease,SLC12 PJD2_k127_2380887_8 945713.IALB_0461 1.358e-132 443.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family aprN - - - - - - - - - - - Peptidase_S8 PJD2_k127_2380887_17 177437.HRM2_32430 1.024e-74 260.0 COG2009@1|root,2ZBTX@2|Bacteria,1RB22@1224|Proteobacteria,42NAY@68525|delta/epsilon subdivisions,2WMPM@28221|Deltaproteobacteria,2MJ7Q@213118|Desulfobacterales 28221|Deltaproteobacteria C Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - ko:K00246 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt PJD2_k127_2380887_1 177437.HRM2_32420 0.0 1037.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2MJ0Y@213118|Desulfobacterales 28221|Deltaproteobacteria C Fumarate reductase flavoprotein C-term sdhA - 1.3.5.1,1.3.5.4 ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C PJD2_k127_2380887_12 177437.HRM2_32410 1.207e-112 379.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WJMH@28221|Deltaproteobacteria,2MHQ3@213118|Desulfobacterales 28221|Deltaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain sdhB - 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_8 PJD2_k127_2380887_19 1379698.RBG1_1C00001G0608 1.034e-72 274.0 COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N PJD2_k127_2380887_15 1122622.ATWJ01000002_gene800 6.956e-78 289.0 COG2114@1|root,COG2197@1|root,COG2114@2|Bacteria,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria 201174|Actinobacteria K PFAM regulatory protein LuxR - - - - - - - - - - - - GerE PJD2_k127_2380887_28 292415.Tbd_2169 1.99e-27 116.0 COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,2VRVY@28216|Betaproteobacteria 28216|Betaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 PJD2_k127_2380887_26 1282361.ABAC402_03970 2.183e-32 135.0 COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,2U6PS@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 PJD2_k127_2380887_33 713587.THITH_07520 3.115e-12 70.0 COG3062@1|root,COG3062@2|Bacteria,1PUNN@1224|Proteobacteria,1TKDR@1236|Gammaproteobacteria,1X21U@135613|Chromatiales 135613|Chromatiales P NapD protein - - - ko:K02570 - - - - ko00000 - - - NapD PJD2_k127_2380887_0 768671.ThimaDRAFT_4410 0.0 1308.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WW7D@135613|Chromatiales 135613|Chromatiales C Molybdopterin oxidoreductase Fe4S4 domain napA - - ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding PJD2_k127_2380887_29 354242.CJJ81176_0804 3.729e-19 94.0 COG3043@1|root,COG3043@2|Bacteria,1NAZB@1224|Proteobacteria,42SN1@68525|delta/epsilon subdivisions,2YPF9@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria C Electron transfer subunit of the periplasmic nitrate reductase complex NapAB napB - - ko:K02568 ko00910,ko01120,map00910,map01120 M00529,M00530 R00798 RC02812 ko00000,ko00001,ko00002 - - - NapB PJD2_k127_2380887_21 313628.LNTAR_11591 4.281e-57 216.0 COG2265@1|root,COG2265@2|Bacteria 2|Bacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr PJD2_k127_2380887_7 1499967.BAYZ01000038_gene2268 2.681e-151 501.0 COG3408@1|root,COG3408@2|Bacteria 2|Bacteria G Glycogen debranching enzyme - - - - - - - - - - - - DUF608,GDE_C,Glyco_hydro_100,S6PP PJD2_k127_2380887_5 1408473.JHXO01000008_gene2652 1.135e-190 603.0 COG0438@1|root,COG0438@2|Bacteria,4NKIM@976|Bacteroidetes 976|Bacteroidetes M Pfam Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 PJD2_k127_2380887_11 945713.IALB_1030 3.679e-114 374.0 COG0363@1|root,COG0363@2|Bacteria 2|Bacteria G glucosamine-6-phosphate deaminase activity nagB - 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso PJD2_k127_2380887_10 98439.AJLL01000104_gene3013 2.204e-115 383.0 COG2805@1|root,COG2805@2|Bacteria,1G0HI@1117|Cyanobacteria,1JJJN@1189|Stigonemataceae 1117|Cyanobacteria NU Type II/IV secretion system protein pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE PJD2_k127_2380887_9 1499967.BAYZ01000195_gene3087 8.073e-128 425.0 COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria 2|Bacteria O smart pdz dhr glgf htrA GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 PJD2_k127_2380887_14 1283284.AZUK01000001_gene550 1.289e-86 295.0 COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,1Y52X@135624|Aeromonadales 135624|Aeromonadales P membrane protein, TerC - - - - - - - - - - - - TerC PJD2_k127_2380887_13 1379270.AUXF01000001_gene2848 4.864e-106 358.0 COG2081@1|root,COG2081@2|Bacteria,1ZUAT@142182|Gemmatimonadetes 142182|Gemmatimonadetes S HI0933-like protein - - - ko:K07007 - - - - ko00000 - - - HI0933_like PJD2_k127_2380887_27 765913.ThidrDRAFT_4503 1.596e-30 140.0 COG0394@1|root,COG1073@1|root,COG3919@1|root,COG0394@2|Bacteria,COG1073@2|Bacteria,COG3919@2|Bacteria,1R61B@1224|Proteobacteria,1S0E7@1236|Gammaproteobacteria,1WYBD@135613|Chromatiales 135613|Chromatiales T TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 PJD2_k127_2380887_22 377629.TERTU_3103 1.186e-47 192.0 COG3379@1|root,COG3379@2|Bacteria 2|Bacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest,Sulfotransfer_1,TPR_16,TPR_19 PJD2_k127_2380887_31 1353529.M899_3029 2.455e-16 91.0 2FK3F@1|root,34BRJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_2380887_30 1123278.KB893583_gene1189 1.626e-16 94.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47K68@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec PJD2_k127_2380887_16 313606.M23134_02978 1.263e-76 265.0 COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,47PUC@768503|Cytophagia 976|Bacteroidetes S KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short PJD2_k127_2380887_25 1279009.ADICEAN_03991 6.78e-33 140.0 COG5624@1|root,COG5624@2|Bacteria,4NZQQ@976|Bacteroidetes 976|Bacteroidetes K domain protein - - - - - - - - - - - - - PJD2_k127_2380887_3 215803.DB30_7421 2.427e-242 767.0 COG1164@1|root,COG1164@2|Bacteria,1Q3C4@1224|Proteobacteria,4393F@68525|delta/epsilon subdivisions,2X49B@28221|Deltaproteobacteria,2YYJ7@29|Myxococcales 28221|Deltaproteobacteria E Oligoendopeptidase f - - - - - - - - - - - - - PJD2_k127_2380887_34 1333523.L593_03595 2.671e-08 64.0 COG3794@1|root,arCOG08132@1|root,arCOG02921@2157|Archaea,arCOG08132@2157|Archaea,2XT3F@28890|Euryarchaeota,23S11@183963|Halobacteria 183963|Halobacteria C COG3794 Plastocyanin - - - - - - - - - - - - Copper-bind PJD2_k127_2380887_32 880073.Calab_0646 2.71e-14 82.0 COG1572@1|root,COG1595@1|root,COG1572@2|Bacteria,COG1595@2|Bacteria,2NRE4@2323|unclassified Bacteria 2|Bacteria K Evidence 5 No homology to any previously reported sequences - - - ko:K03088 - - - - ko00000,ko03021 - - - CARDB,Sigma70_r4_2 PJD2_k127_2380887_6 926567.TheveDRAFT_0030 1.956e-160 514.0 COG4992@1|root,COG4992@2|Bacteria,3TAN5@508458|Synergistetes 508458|Synergistetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 PJD2_k127_2380887_20 502025.Hoch_3429 1.145e-65 229.0 COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,42YM8@68525|delta/epsilon subdivisions,2WTXS@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine - - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR PJD2_k127_2380887_18 1192034.CAP_7219 2.911e-73 257.0 COG2172@1|root,COG2197@1|root,COG2172@2|Bacteria,COG2197@2|Bacteria,1PGJ3@1224|Proteobacteria,4315J@68525|delta/epsilon subdivisions,2WWDE@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase-like ATPase domain - - - - - - - - - - - - HATPase_c_2,Response_reg PJD2_k127_2424231_1 1254432.SCE1572_40880 4.19e-31 138.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1MWVZ@1224|Proteobacteria,43APJ@68525|delta/epsilon subdivisions,2X638@28221|Deltaproteobacteria,2Z38P@29|Myxococcales 28221|Deltaproteobacteria KLT Protein kinase domain - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase PJD2_k127_2424231_0 945713.IALB_2989 2.007e-161 535.0 COG0616@1|root,COG0616@2|Bacteria 2|Bacteria OU serine-type peptidase activity sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 PJD2_k127_2446049_3 1232410.KI421418_gene2310 2.769e-61 224.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,43S2J@69541|Desulfuromonadales 28221|Deltaproteobacteria OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 PJD2_k127_2446049_2 945713.IALB_0376 1.78e-81 291.0 COG1207@1|root,COG1207@2|Bacteria 2|Bacteria M glucosamine-1-phosphate N-acetyltransferase activity glmU - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_4 PJD2_k127_2446049_4 1499967.BAYZ01000060_gene5991 2.763e-56 203.0 COG1403@1|root,COG1403@2|Bacteria,2NPJD@2323|unclassified Bacteria 2|Bacteria L HNH endonuclease MA20_20605 - - - - - - - - - - - HNH,HNH_5 PJD2_k127_2446049_0 1379698.RBG1_1C00001G1760 2.947e-116 389.0 COG1030@1|root,COG1030@2|Bacteria,2NNMU@2323|unclassified Bacteria 2|Bacteria O NfeD-like C-terminal, partner-binding nfeD - - ko:K07403 - - - - ko00000 - - - CLP_protease,NfeD PJD2_k127_2446049_1 1379698.RBG1_1C00001G1759 2.511e-104 344.0 COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria 2|Bacteria O prohibitin homologues hflC - - - - - - - - - - - Band_7 PJD2_k127_2446049_5 1173029.JH980292_gene2288 5.88e-31 138.0 COG0457@1|root,COG0457@2|Bacteria,1GD9N@1117|Cyanobacteria,1HH3D@1150|Oscillatoriales 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 PJD2_k127_2446049_10 1041930.Mtc_1015 5.929e-05 56.0 COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03042@2157|Archaea,2Y7M7@28890|Euryarchaeota,2NBM0@224756|Methanomicrobia 224756|Methanomicrobia S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 PJD2_k127_2446049_9 880073.Calab_0143 2.566e-08 67.0 COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria 2|Bacteria KT Peptidase M56 - - - - - - - - - - - - Amidase_6,DUF4309,DUF5301 PJD2_k127_2446049_7 1095767.CAHD01000224_gene2097 2.335e-11 75.0 COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4F18H@85016|Cellulomonadaceae 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf PJD2_k127_2446049_11 1442599.JAAN01000024_gene1904 0.0001124 53.0 COG0810@1|root,COG0810@2|Bacteria,1PDQZ@1224|Proteobacteria,1SWIV@1236|Gammaproteobacteria,1X88P@135614|Xanthomonadales 135614|Xanthomonadales M Gram-negative bacterial TonB protein C-terminal - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C PJD2_k127_2446049_8 392500.Swoo_4844 9.119e-09 59.0 2EZNE@1|root,33STF@2|Bacteria,1QZHA@1224|Proteobacteria,1T46W@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_2450742_2 631362.Thi970DRAFT_04902 1.147e-14 85.0 2BXQF@1|root,32R1T@2|Bacteria,1RJTZ@1224|Proteobacteria,1SUVI@1236|Gammaproteobacteria,1X1W6@135613|Chromatiales 135613|Chromatiales - - - - - ko:K02008 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - - PJD2_k127_2450742_0 123214.PERMA_0830 1.353e-69 242.0 COG0310@1|root,COG0310@2|Bacteria,2G4E9@200783|Aquificae 200783|Aquificae P Cobalt uptake substrate-specific transmembrane region - - - ko:K02007 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiM PJD2_k127_2450742_1 631362.Thi970DRAFT_04905 2.018e-24 108.0 COG5266@1|root,COG5266@2|Bacteria,1NBJ8@1224|Proteobacteria,1SGZC@1236|Gammaproteobacteria,1X2PI@135613|Chromatiales 135613|Chromatiales P PFAM Nickel transport complex, NikM subunit, transmembrane - - - ko:K16915 ko02010,map02010 M00246 - - ko00000,ko00001,ko00002,ko02000 - - - - PJD2_k127_2472348_2 649747.HMPREF0083_01392 0.0006281 49.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,26R7Y@186822|Paenibacillaceae 91061|Bacilli O Belongs to the peptidase S8 family apr - - - - - - - - - - - Peptidase_S8 PJD2_k127_2472348_1 1173026.Glo7428_0554 3.89e-35 141.0 COG2940@1|root,COG2940@2|Bacteria 2|Bacteria K SET domain - - - ko:K07117 - - - - ko00000 - - - SET PJD2_k127_2472348_0 204669.Acid345_4118 4.609e-65 227.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia 57723|Acidobacteria KLTU Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase PJD2_k127_2482138_1 502025.Hoch_4669 4.011e-36 147.0 COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales 28221|Deltaproteobacteria D Cellulose biosynthesis protein BcsQ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 PJD2_k127_2482138_2 880073.Calab_0680 2.189e-18 102.0 COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria 2|Bacteria T Anti-sigma factor antagonist - - - ko:K04749,ko:K06378 - - - - ko00000,ko03021 - - - STAS,STAS_2 PJD2_k127_2482138_3 880073.Calab_2295 1.604e-15 93.0 COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria 2|Bacteria T Anti-sigma factor antagonist spoIIAA - - ko:K02066,ko:K04749 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000,ko03021 3.A.1.27 - - APH,STAS,STAS_2 PJD2_k127_2482138_0 880073.Calab_0681 1.655e-159 557.0 COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria 2|Bacteria KT Sigma factor PP2C-like phosphatases pkn5 - 2.7.11.1,3.1.3.3 ko:K04757,ko:K07315 - - - - ko00000,ko01000,ko01001,ko03021 - - - AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1 PJD2_k127_2482138_4 1379698.RBG1_1C00001G1334 1.668e-07 57.0 COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria 2|Bacteria I Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 PJD2_k127_249363_2 1209989.TepiRe1_1498 9.544e-35 141.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,42EZU@68295|Thermoanaerobacterales 186801|Clostridia L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N PJD2_k127_249363_1 635013.TherJR_2805 9.742e-46 179.0 COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,267E8@186807|Peptococcaceae 186801|Clostridia T TIGRFAM Diguanylate cyclase - - - - - - - - - - - - GAF,GAF_2,GGDEF PJD2_k127_249363_0 234267.Acid_4597 2.692e-169 543.0 COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria 57723|Acidobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N PJD2_k127_2510752_1 1125863.JAFN01000001_gene413 5.988e-70 243.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42URP@68525|delta/epsilon subdivisions,2WQFZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 PJD2_k127_2510752_2 1125863.JAFN01000001_gene412 8.891e-56 202.0 COG0468@1|root,COG0468@2|Bacteria,1RIBX@1224|Proteobacteria,43078@68525|delta/epsilon subdivisions,2WVGC@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - - - - - - - - - - - PJD2_k127_2510752_4 240015.ACP_1945 4.95e-38 149.0 COG2318@1|root,COG2318@2|Bacteria,3Y594@57723|Acidobacteria,2JJNR@204432|Acidobacteriia 204432|Acidobacteriia S DinB family - - - - - - - - - - - - DinB_2 PJD2_k127_2510752_6 1121324.CLIT_2c01420 7.125e-28 117.0 COG0389@1|root,COG0389@2|Bacteria,1VEU0@1239|Firmicutes,24RTW@186801|Clostridia 186801|Clostridia L Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Cdd1 PJD2_k127_2510752_3 1121406.JAEX01000001_gene518 1.033e-42 168.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S7S@68525|delta/epsilon subdivisions,2WNFR@28221|Deltaproteobacteria,2M9XW@213115|Desulfovibrionales 28221|Deltaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GAF_2,GGDEF,PAS,PAS_3,PAS_4 PJD2_k127_2510752_0 768671.ThimaDRAFT_0215 8.383e-125 418.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria 1236|Gammaproteobacteria L nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS PJD2_k127_2510752_5 744980.TRICHSKD4_4342 6.342e-29 118.0 COG0204@1|root,COG0204@2|Bacteria,1RA8V@1224|Proteobacteria,2U5DY@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-transferase plsC - - - - - - - - - - - Acyltransferase PJD2_k127_2549025_0 1125863.JAFN01000001_gene2857 6.093e-54 206.0 COG3391@1|root,COG3391@2|Bacteria,1RJQF@1224|Proteobacteria,42VW9@68525|delta/epsilon subdivisions,2WRUS@28221|Deltaproteobacteria 28221|Deltaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - - PJD2_k127_2549025_1 1125863.JAFN01000001_gene2858 1.075e-53 201.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,42RAY@68525|delta/epsilon subdivisions,2WMP5@28221|Deltaproteobacteria 28221|Deltaproteobacteria H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec PJD2_k127_2557701_6 864051.BurJ1DRAFT_2685 2.248e-43 167.0 COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome b/b6/petB - - - - - - - - - - - - Ni_hydr_CYTB PJD2_k127_2557701_0 314285.KT71_18426 9.435e-171 550.0 28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c bacterial - - - - - - - - - - - - Cytochrome_C554,Cytochrome_cB PJD2_k127_2557701_8 1168034.FH5T_01635 4.216e-24 111.0 COG0226@1|root,COG0509@1|root,COG0226@2|Bacteria,COG0509@2|Bacteria 2|Bacteria E glycine decarboxylation via glycine cleavage system gcvH - - ko:K02040,ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,ko02010,ko02020,ko05152,map00260,map00630,map01100,map01110,map01130,map01200,map02010,map02020,map05152 M00222,M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - GCV_H,PBP_like_2 PJD2_k127_2557701_5 1121920.AUAU01000012_gene2649 1.518e-83 285.0 COG0437@1|root,COG0437@2|Bacteria,3Y5RE@57723|Acidobacteria 57723|Acidobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_11 PJD2_k127_2557701_2 204669.Acid345_2602 3.197e-124 416.0 COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria 57723|Acidobacteria C Polysulphide reductase, NrfD - - - - - - - - - - - - NrfD PJD2_k127_2557701_3 945713.IALB_2428 2.216e-116 394.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA PJD2_k127_2557701_1 945713.IALB_2429 1.897e-160 518.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K02481,ko:K07713,ko:K07714 ko02020,map02020 M00499,M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_2557701_7 234267.Acid_0393 6.263e-40 154.0 COG1913@1|root,COG1913@2|Bacteria 2|Bacteria S metallopeptidase activity - - - ko:K06974 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M54 PJD2_k127_2557701_4 706587.Desti_1514 2.29e-87 301.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42PQM@68525|delta/epsilon subdivisions,2WJIF@28221|Deltaproteobacteria,2MRCK@213462|Syntrophobacterales 28221|Deltaproteobacteria Q ubiE/COQ5 methyltransferase family - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - HTH_20,Methyltransf_31 PJD2_k127_2557701_9 1184267.A11Q_2587 1.083e-18 98.0 2DIDK@1|root,302WD@2|Bacteria,1P7I4@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - PJD2_k127_2565107_0 1121920.AUAU01000001_gene2279 3.08e-53 191.0 COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria 57723|Acidobacteria S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 PJD2_k127_2565107_1 118163.Ple7327_3262 1.204e-38 151.0 COG0607@1|root,COG0607@2|Bacteria,1G896@1117|Cyanobacteria,3VKUG@52604|Pleurocapsales 1117|Cyanobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese PJD2_k127_2565107_2 234267.Acid_3202 1.526e-29 130.0 COG0596@1|root,COG0596@2|Bacteria,3Y89S@57723|Acidobacteria 57723|Acidobacteria S PFAM alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 PJD2_k127_2565107_3 1267534.KB906754_gene3511 0.0004604 43.0 COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria 57723|Acidobacteria L 5'-3' exonuclease, N-terminal resolvase-like domain - - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N PJD2_k127_2603341_6 518766.Rmar_2635 3.383e-34 137.0 COG1293@1|root,COG1293@2|Bacteria,4NGP5@976|Bacteroidetes,1FJ0X@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes K Fibronectin-binding protein A N-terminus (FbpA) - - - - - - - - - - - - DUF814,FbpA PJD2_k127_2603341_0 667014.Thein_2111 7.297e-142 474.0 COG3276@1|root,COG3276@2|Bacteria,2GH20@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Elongation factor SelB, winged helix - - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 PJD2_k127_2603341_1 243231.GSU3102 9.047e-138 452.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,43TD6@69541|Desulfuromonadales 28221|Deltaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase PJD2_k127_2603341_5 243231.GSU3103 2.798e-51 194.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,43TP7@69541|Desulfuromonadales 28221|Deltaproteobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 PJD2_k127_2603341_2 498761.HM1_1083 2.393e-132 431.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia 186801|Clostridia J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 PJD2_k127_2603341_4 316067.Geob_0684 2.769e-82 286.0 COG3872@1|root,COG3872@2|Bacteria,1RCB0@1224|Proteobacteria,42R3I@68525|delta/epsilon subdivisions,2WMZR@28221|Deltaproteobacteria,43U2U@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF1385) - - - - - - - - - - - - DUF1385 PJD2_k127_2603341_7 1396141.BATP01000029_gene2278 2.148e-24 106.0 COG0254@1|root,COG0254@2|Bacteria,46T4W@74201|Verrucomicrobia,2IUJ0@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L31 - - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 PJD2_k127_2603341_3 1382359.JIAL01000001_gene1736 5.194e-124 400.0 COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia 204432|Acidobacteriia K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind PJD2_k127_2608008_4 1394178.AWOO02000004_gene2412 6.35e-14 79.0 COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4ENET@85012|Streptosporangiales 201174|Actinobacteria M Glycosyl transferase 4-like - - - ko:K19424 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_2608008_1 1396141.BATP01000036_gene3854 2.838e-102 344.0 COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,2IU1W@203494|Verrucomicrobiae 2|Bacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA PJD2_k127_2608008_2 517418.Ctha_0364 3.326e-67 238.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1FEH6@1090|Chlorobi 1090|Chlorobi GM Bacterial sugar transferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 PJD2_k127_2608008_0 479434.Sthe_1140 5.678e-114 378.0 COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi 200795|Chloroflexi E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 PJD2_k127_2608008_3 357808.RoseRS_1340 6.323e-26 114.0 COG0438@1|root,COG0438@2|Bacteria,2G7W9@200795|Chloroflexi,3772B@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 PJD2_k127_2633230_3 240016.ABIZ01000001_gene4084 3.649e-06 57.0 COG0457@1|root,COG0457@2|Bacteria,46VSG@74201|Verrucomicrobia 74201|Verrucomicrobia S TPR repeat - - - - - - - - - - - - TPR_1,TPR_16,TPR_2,TPR_8 PJD2_k127_2633230_1 620914.JH621248_gene3091 5.869e-87 298.0 COG2866@1|root,COG2866@2|Bacteria,4NPSD@976|Bacteroidetes,1I880@117743|Flavobacteriia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 PJD2_k127_2633230_0 195250.CM001776_gene3867 5.591e-101 343.0 COG3608@1|root,COG3608@2|Bacteria,1G167@1117|Cyanobacteria 1117|Cyanobacteria S succinylglutamate desuccinylase aspartoacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA PJD2_k127_2633230_2 1121952.ATXT01000020_gene1664 2.886e-47 173.0 COG0189@1|root,COG0189@2|Bacteria,2HXBM@201174|Actinobacteria,4FK87@85023|Microbacteriaceae 201174|Actinobacteria HJ RimK-like ATP-grasp domain rimK - 6.3.2.43 ko:K05827,ko:K05844 ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230 M00031 R09775 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko03009 - - - RimK,TrkA_C PJD2_k127_2658485_5 880073.Calab_2214 3.769e-18 92.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - ko:K09800 - - - - ko00000,ko02000 - - - - PJD2_k127_2658485_2 1085623.GNIT_3229 1.281e-76 268.0 COG5309@1|root,COG5309@2|Bacteria,1Q5JR@1224|Proteobacteria,1SJJ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Glycosyl hydrolases family 17 - - - - - - - - - - - - Glyco_hydro_17 PJD2_k127_2658485_1 1121930.AQXG01000002_gene2362 1.397e-155 505.0 2DBJC@1|root,2Z9K5@2|Bacteria,4P1C2@976|Bacteroidetes,1IWD2@117747|Sphingobacteriia 976|Bacteroidetes G Glycosyl hydrolase family 47 - - - - - - - - - - - - Glyco_hydro_47 PJD2_k127_2658485_0 1356852.N008_02700 3.408e-311 977.0 COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,47KZ5@768503|Cytophagia 976|Bacteroidetes G PFAM Glycosyl Hydrolase - - - - - - - - - - - - Glyco_hydro_92 PJD2_k127_2658485_4 518766.Rmar_0637 3.271e-19 95.0 2FDJV@1|root,345M5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_2658485_3 518766.Rmar_0638 5.509e-48 179.0 COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1FIMH@1100069|Bacteroidetes Order II. Incertae sedis 2|Bacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF PJD2_k127_2662902_3 344747.PM8797T_16887 4.832e-10 72.0 COG1807@1|root,COG1807@2|Bacteria,2IZ75@203682|Planctomycetes 203682|Planctomycetes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 PJD2_k127_2662902_1 525904.Tter_2814 2.742e-99 336.0 COG0673@1|root,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria 2|Bacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA PJD2_k127_2662902_0 1298858.AUEL01000014_gene616 2.618e-116 385.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,43N46@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 PJD2_k127_2662902_2 593117.TGAM_2153 1.958e-78 273.0 COG0463@1|root,arCOG00896@2157|Archaea,2XT4C@28890|Euryarchaeota,244ZH@183968|Thermococci 183968|Thermococci M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 PJD2_k127_2662902_4 858215.Thexy_2232 1.543e-09 67.0 COG1287@1|root,COG1287@2|Bacteria,1UHTE@1239|Firmicutes,25GD6@186801|Clostridia,42HYG@68295|Thermoanaerobacterales 186801|Clostridia M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 PJD2_k127_2687165_5 67352.JODS01000020_gene3879 2.911e-30 126.0 COG3832@1|root,COG3832@2|Bacteria,2IFNX@201174|Actinobacteria 201174|Actinobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - Polyketide_cyc2 PJD2_k127_2687165_8 1396858.Q666_05180 1.583e-20 94.0 COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,469AA@72275|Alteromonadaceae 1236|Gammaproteobacteria P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 PJD2_k127_2687165_1 1125863.JAFN01000001_gene69 1.543e-108 365.0 COG4773@1|root,COG4773@2|Bacteria,1QCTH@1224|Proteobacteria,42PPC@68525|delta/epsilon subdivisions,2WIS8@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Receptor - - - - - - - - - - - - - PJD2_k127_2687165_3 1122201.AUAZ01000008_gene354 1.759e-94 347.0 COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,46671@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane lipoprotein-sorting protein VPA0557 - - - - - - - - - - - LolA_like PJD2_k127_2687165_0 1122201.AUAZ01000008_gene353 8.109e-274 881.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,4658X@72275|Alteromonadaceae 1236|Gammaproteobacteria S exporters of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL PJD2_k127_2687165_6 266117.Rxyl_1608 4.315e-28 117.0 COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria 84995|Rubrobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 PJD2_k127_2687165_2 1208323.B30_18882 1.75e-103 344.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox PJD2_k127_2687165_4 234267.Acid_4617 1.177e-74 265.0 COG0457@1|root,COG0457@2|Bacteria,3Y4T0@57723|Acidobacteria 57723|Acidobacteria S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 PJD2_k127_2687165_7 945713.IALB_2117 1.791e-25 123.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - Peptidase_C10,Phage-tail_3,Prophage_tail,SLH PJD2_k127_2693073_0 1123267.JONN01000001_gene1238 3.999e-219 713.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - Cupin_2,MRJP PJD2_k127_2693073_1 1408310.JHUW01000007_gene357 1.756e-39 160.0 2C1YS@1|root,2ZD2Y@2|Bacteria 2|Bacteria S Protease prsW family - - - - - - - - - - - - PrsW-protease PJD2_k127_2693073_2 1125863.JAFN01000001_gene2857 0.0005285 46.0 COG3391@1|root,COG3391@2|Bacteria,1RJQF@1224|Proteobacteria,42VW9@68525|delta/epsilon subdivisions,2WRUS@28221|Deltaproteobacteria 28221|Deltaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - - PJD2_k127_2693084_0 880073.Calab_0811 1.568e-193 619.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria 2|Bacteria EU peptidase S9 prolyl oligopeptidase active site - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - PD40,Peptidase_S9 PJD2_k127_2693084_2 1049564.TevJSym_at00210 3.33e-113 388.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1J58Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 PJD2_k127_2693084_4 1519464.HY22_06375 7.06e-72 256.0 COG0438@1|root,COG0438@2|Bacteria,1FDVR@1090|Chlorobi 1090|Chlorobi M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 PJD2_k127_2693084_5 351160.LRC548 5.233e-68 243.0 COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia 224756|Methanomicrobia M Glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3 PJD2_k127_2693084_6 1158338.JNLJ01000001_gene179 1.003e-50 192.0 COG0279@1|root,COG0279@2|Bacteria,2G410@200783|Aquificae 200783|Aquificae G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 PJD2_k127_2693084_1 1123354.AUDR01000013_gene539 1.209e-117 396.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria,1KRN9@119069|Hydrogenophilales 119069|Hydrogenophilales M pfkB family carbohydrate kinase - - 2.7.1.167 ko:K21344 ko00540,map00540 M00064 R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - PfkB PJD2_k127_2693084_10 1123274.KB899431_gene3241 0.0005446 45.0 2AU0F@1|root,31JKB@2|Bacteria 2|Bacteria S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - PJD2_k127_2693084_7 445973.CLOBAR_00769 4.44e-41 153.0 2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes,24KKM@186801|Clostridia 186801|Clostridia S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - PJD2_k127_2693084_3 262768.PAM_250 3.46e-74 255.0 2B9ZZ@1|root,323DM@2|Bacteria,3WUUY@544448|Tenericutes 2|Bacteria S COG NOG15344 non supervised orthologous group - - - - - - - - - - - - - PJD2_k127_2693084_8 411463.EUBVEN_00035 2.933e-17 82.0 2ED6K@1|root,3373A@2|Bacteria,1VI2S@1239|Firmicutes,24QZV@186801|Clostridia 186801|Clostridia S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - - - - - - - - - - - PJD2_k127_2707418_0 1379698.RBG1_1C00001G0297 2.244e-179 568.0 COG4881@1|root,COG4881@2|Bacteria 2|Bacteria - - cbcU - - - - - - - - - - - NrfD PJD2_k127_2707418_1 1121440.AUMA01000008_gene854 2.259e-69 241.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales 28221|Deltaproteobacteria E Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine nifS-1 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 PJD2_k127_2725139_1 504472.Slin_6199 7.323e-50 183.0 COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,47XD5@768503|Cytophagia 976|Bacteroidetes J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 PJD2_k127_2725139_0 880073.Calab_1288 3.283e-76 276.0 COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria 2|Bacteria C TIGRFAM geranylgeranyl reductase - - 1.3.99.38 ko:K21401 - - - - ko00000,ko01000 - - - FAD_binding_3 PJD2_k127_2728603_3 1121468.AUBR01000006_gene385 8.427e-37 151.0 COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,42FXU@68295|Thermoanaerobacterales 186801|Clostridia S Belongs to the multicopper oxidase YfiH RL5 family yfiH - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 PJD2_k127_2728603_6 500153.JOEK01000020_gene2734 0.0006375 52.0 COG3420@1|root,COG5297@1|root,COG3420@2|Bacteria,COG5297@2|Bacteria,2I8D7@201174|Actinobacteria 201174|Actinobacteria P Parallel beta-helix repeats - - - - - - - - - - - - Beta_helix PJD2_k127_2728603_0 518766.Rmar_1183 2.265e-216 703.0 COG0823@1|root,COG1262@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FIPY@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes EU Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,PD40,Peptidase_S9 PJD2_k127_2728603_2 1034345.CAEM01000058_gene412 2.149e-56 216.0 COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CUE1@84998|Coriobacteriia 84998|Coriobacteriia P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF87 PJD2_k127_2728603_5 1267535.KB906767_gene2130 1.032e-13 80.0 COG0457@1|root,COG0457@2|Bacteria,3Y4S2@57723|Acidobacteria 57723|Acidobacteria NU TPR repeat - - - - - - - - - - - - TPR_11,TPR_16,TPR_2,TPR_6,TPR_8 PJD2_k127_2728603_1 269799.Gmet_0194 2.459e-81 287.0 COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,43U9E@69541|Desulfuromonadales 28221|Deltaproteobacteria S Belongs to the LarC family - - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 PJD2_k127_2728603_4 398767.Glov_3164 4.537e-17 81.0 COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase - - - ko:K06898 - - - - ko00000 - - - AIRC PJD2_k127_2752651_5 1169144.KB910964_gene2953 1.998e-07 55.0 2EHF3@1|root,33B70@2|Bacteria,1VP4D@1239|Firmicutes,4IM7K@91061|Bacilli,1ZK47@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - PJD2_k127_2752651_2 935845.JADQ01000047_gene2472 8.533e-115 381.0 COG3509@1|root,COG3509@2|Bacteria,1UZE4@1239|Firmicutes,4I68A@91061|Bacilli,26RD5@186822|Paenibacillaceae 91061|Bacilli Q Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 PJD2_k127_2752651_0 1191523.MROS_1592 7.417e-241 760.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF PJD2_k127_2752651_4 1408473.JHXO01000009_gene3318 6.924e-30 132.0 28HW2@1|root,2Z825@2|Bacteria,4NF6G@976|Bacteroidetes,2FMR4@200643|Bacteroidia 976|Bacteroidetes S Peptide-N-glycosidase F, N terminal - - - - - - - - - - - - N-glycanase_C,N-glycanase_N PJD2_k127_2752651_3 1191523.MROS_1577 1.245e-107 357.0 COG2152@1|root,COG2152@2|Bacteria 2|Bacteria G transferase activity, transferring glycosyl groups - - 2.4.1.319,2.4.1.320 ko:K18785 - - R10811,R10829 RC00049 ko00000,ko01000 - - - Glyco_hydro_130 PJD2_k127_2752651_1 266117.Rxyl_0070 2.21e-141 487.0 COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria 201174|Actinobacteria G PFAM Glycoside hydrolase, family 38 - - 3.2.1.170,3.2.1.24 ko:K01191,ko:K15524 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04131 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C PJD2_k127_2849746_9 67373.JOBF01000001_gene6250 4.333e-07 63.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator, SARP family - - - - - - - - - - - - BTAD,NB-ARC,TPR_12,Trans_reg_C PJD2_k127_2849746_8 1158345.JNLL01000001_gene902 2.355e-09 63.0 COG1579@1|root,COG1579@2|Bacteria,2G4TK@200783|Aquificae 200783|Aquificae S C4-type zinc ribbon domain - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 PJD2_k127_2849746_4 861299.J421_3386 1.407e-27 118.0 COG1762@1|root,COG1762@2|Bacteria,1ZTIY@142182|Gemmatimonadetes 142182|Gemmatimonadetes G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 PJD2_k127_2849746_2 518766.Rmar_1702 2.895e-58 215.0 COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1FIU8@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N PJD2_k127_2849746_3 1191523.MROS_0141 8.982e-37 153.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity waaC - - ko:K02841,ko:K02843,ko:K12982 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 PJD2_k127_2849746_0 1379698.RBG1_1C00001G1613 1.316e-69 257.0 COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria 2|Bacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,PEGA,Pkinase PJD2_k127_2849746_1 1499967.BAYZ01000167_gene6734 1.647e-58 211.0 COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria 2|Bacteria T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 PJD2_k127_2849746_5 706587.Desti_3086 1.188e-24 118.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,42S8N@68525|delta/epsilon subdivisions,2WNCI@28221|Deltaproteobacteria,2MRX8@213462|Syntrophobacterales 28221|Deltaproteobacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,Yop-YscD_cpl PJD2_k127_2849746_6 1123065.ATWL01000002_gene1743 2.415e-21 96.0 COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria 201174|Actinobacteria K Cold shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD PJD2_k127_2849746_7 653948.CCA22532 3.834e-16 91.0 COG3914@1|root,KOG4626@2759|Eukaryota 2759|Eukaryota O protein N-acetylglucosaminyltransferase activity - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.255 ko:K09667 ko00514,ko04931,map00514,map04931 - R09304,R09676 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003,ko03036 - GT41 - Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8 PJD2_k127_2859445_3 278957.ABEA03000166_gene4028 2.821e-19 104.0 2DBTD@1|root,2ZAXA@2|Bacteria,46WE4@74201|Verrucomicrobia,3K9X9@414999|Opitutae 414999|Opitutae S Heparinase II/III-like protein - - - - - - - - - - - - DUF4962,Hepar_II_III PJD2_k127_2859445_0 1116472.MGMO_145c00110 1.621e-130 434.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria,1XE7P@135618|Methylococcales 135618|Methylococcales C Alcohol dehydrogenase GroES-like domain - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N PJD2_k127_2859445_1 383372.Rcas_2505 3.563e-48 192.0 COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia 32061|Chloroflexia M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - PJD2_k127_2859445_2 382464.ABSI01000011_gene2976 1.993e-44 165.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 PJD2_k127_2859445_4 1121440.AUMA01000009_gene708 2.94e-07 55.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 PJD2_k127_2889129_1 880073.Calab_3769 1.042e-270 852.0 COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria 2|Bacteria E Prolyl oligopeptidase, N-terminal beta-propeller domain ptrB GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N PJD2_k127_2889129_12 945713.IALB_0188 1.333e-24 123.0 COG1649@1|root,COG4733@1|root,COG1649@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity J - 3.2.1.11,3.2.1.18,3.2.1.35 ko:K01186,ko:K01197,ko:K05988,ko:K11931,ko:K21449 ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,ko04142,map00500,map00511,map00531,map00600,map01100,map02026,map04142 M00076,M00077 R04018,R07824,R07825,R10905,R11309 RC00028,RC00077 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02000,ko02042 1.B.40.2 GH33,GH66 - DUF1983,DUF3672,Phage-tail_3 PJD2_k127_2889129_3 91464.S7335_5339 3.178e-201 683.0 COG2133@1|root,COG2911@1|root,COG2931@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1GJ0F@1117|Cyanobacteria,1H1MZ@1129|Synechococcus 1117|Cyanobacteria Q pyrroloquinoline quinone binding - - - - - - - - - - - - - PJD2_k127_2889129_2 1124780.ANNU01000008_gene2769 3.128e-269 843.0 COG1164@1|root,COG1164@2|Bacteria,4NJFW@976|Bacteroidetes,47TFT@768503|Cytophagia 976|Bacteroidetes E Angiotensin-converting enzyme - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 PJD2_k127_2889129_6 926550.CLDAP_19010 3.025e-85 286.0 COG2818@1|root,COG2818@2|Bacteria,2G78E@200795|Chloroflexi 200795|Chloroflexi L Methyladenine glycosylase - - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco PJD2_k127_2889129_13 867900.Celly_2994 1.075e-13 80.0 2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,1I3ZA@117743|Flavobacteriia,1F9GE@104264|Cellulophaga 976|Bacteroidetes - - - - - - - - - - - - - - - PJD2_k127_2889129_11 33876.JNXY01000023_gene5166 8.126e-28 118.0 COG2207@1|root,COG4978@1|root,COG2207@2|Bacteria,COG4978@2|Bacteria,2IS9W@201174|Actinobacteria,4DGGS@85008|Micromonosporales 201174|Actinobacteria KT Bacterial transcription activator, effector binding domain - - - ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 PJD2_k127_2889129_14 1380393.JHVP01000019_gene46 1.449e-10 72.0 COG2220@1|root,COG2220@2|Bacteria,2GMTR@201174|Actinobacteria 201174|Actinobacteria E Zn-dependent hydrolases of the beta-lactamase fold - - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 PJD2_k127_2889129_8 1380394.JADL01000018_gene1896 2.683e-50 196.0 2EX4W@1|root,33QFX@2|Bacteria,1NRWJ@1224|Proteobacteria,2UNPH@28211|Alphaproteobacteria,2JVSM@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - PJD2_k127_2889129_7 204669.Acid345_1455 6.15e-60 216.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia 204432|Acidobacteriia KLT Tetratricopeptide repeats - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C PJD2_k127_2889129_16 1242864.D187_002928 4.483e-08 60.0 COG4968@1|root,COG4968@2|Bacteria,1QXNR@1224|Proteobacteria,43C4N@68525|delta/epsilon subdivisions,2WRDZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria NU Pfam:N_methyl_2 pilA-N - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin_PilA PJD2_k127_2889129_10 1237149.C900_00073 6.131e-42 162.0 COG0457@1|root,COG0457@2|Bacteria 1237149.C900_00073|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - PJD2_k127_2889129_4 1237149.C900_00072 6.486e-99 332.0 COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,47PE5@768503|Cytophagia 976|Bacteroidetes L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku - - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku PJD2_k127_2889129_5 402626.Rpic_0271 3.422e-97 321.0 COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2VM0T@28216|Betaproteobacteria,1K0J1@119060|Burkholderiaceae 28216|Betaproteobacteria S Intracellular protease, PfpI family - - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI PJD2_k127_2889129_9 926560.KE387023_gene2407 3.078e-43 164.0 COG1832@1|root,COG1832@2|Bacteria 2|Bacteria S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 PJD2_k127_2889129_15 1033991.RLEG12_16980 7.885e-10 68.0 COG1670@1|root,COG1670@2|Bacteria,1RHBD@1224|Proteobacteria,2U80N@28211|Alphaproteobacteria,4BDWY@82115|Rhizobiaceae 28211|Alphaproteobacteria J Acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 PJD2_k127_2889129_0 1237149.C900_00071 2.176e-302 945.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia 976|Bacteroidetes L DNA polymerase Ligase (LigD) - - - - - - - - - - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N PJD2_k127_2894102_1 1128421.JAGA01000003_gene2811 1.399e-118 389.0 COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria 2|Bacteria E Threonine synthase MA20_41710 - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP PJD2_k127_2894102_0 497964.CfE428DRAFT_1447 2.948e-213 687.0 COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia 74201|Verrucomicrobia OU PA domain - - - - - - - - - - - - PA,PD40,PDZ_2,Peptidase_M28 PJD2_k127_2894102_2 338966.Ppro_3278 1.48e-113 372.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,43BJA@68525|delta/epsilon subdivisions,2WME6@28221|Deltaproteobacteria,43TIC@69541|Desulfuromonadales 28221|Deltaproteobacteria O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 PJD2_k127_2894102_4 1121448.DGI_2478 4.905e-14 85.0 COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales 28221|Deltaproteobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 PJD2_k127_2894102_5 96561.Dole_2410 0.0002852 53.0 COG0457@1|root,COG0457@2|Bacteria,1RKQQ@1224|Proteobacteria,42T9T@68525|delta/epsilon subdivisions,2WPQ0@28221|Deltaproteobacteria,2MN67@213118|Desulfobacterales 28221|Deltaproteobacteria S Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - PMT_2,TPR_16,TPR_2,TPR_8 PJD2_k127_2894102_3 765420.OSCT_1998 4.931e-75 269.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT_2 PJD2_k127_2922015_0 1267535.KB906767_gene3785 1.509e-91 319.0 COG0034@1|root,COG0034@2|Bacteria,3Y3RG@57723|Acidobacteria,2JHXM@204432|Acidobacteriia 204432|Acidobacteriia F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran PJD2_k127_2934444_3 313628.LNTAR_10846 1.113e-60 214.0 COG1060@1|root,COG1060@2|Bacteria 2|Bacteria H 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity mqnC GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285 ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120 M00378 R08588,R09396,R10667 RC00021,RC01381,RC02329,RC03002,RC03007,RC03234 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM PJD2_k127_2934444_6 880073.Calab_0646 1.939e-14 88.0 COG1572@1|root,COG1595@1|root,COG1572@2|Bacteria,COG1595@2|Bacteria,2NRE4@2323|unclassified Bacteria 2|Bacteria K Evidence 5 No homology to any previously reported sequences - - - ko:K03088 - - - - ko00000,ko03021 - - - CARDB,Sigma70_r4_2 PJD2_k127_2934444_4 1121918.ARWE01000001_gene527 7.83e-30 128.0 COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,42V8E@68525|delta/epsilon subdivisions,2WS8I@28221|Deltaproteobacteria,43SQU@69541|Desulfuromonadales 28221|Deltaproteobacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - AsmA PJD2_k127_2934444_5 7668.SPU_003538-tr 1.32e-21 107.0 COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta 33154|Opisthokonta M protein localization to T-tubule - - - ko:K10380,ko:K15502 ko04624,ko05205,map04624,map05205 - - - ko00000,ko00001,ko01009,ko03400,ko04812 - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5 PJD2_k127_2934444_0 234267.Acid_5749 3.231e-207 681.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 PJD2_k127_2934444_1 502025.Hoch_1577 4.863e-183 604.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales 28221|Deltaproteobacteria KLTU Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase PJD2_k127_2934444_2 234267.Acid_5940 1.677e-135 454.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria 57723|Acidobacteria KLTU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase PJD2_k127_2982850_2 204669.Acid345_1270 1.988e-160 511.0 COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia 204432|Acidobacteriia Q Flavin containing amine oxidoreductase - - - - - - - - - - - - NAD_binding_8 PJD2_k127_2982850_6 234267.Acid_7336 4.942e-106 362.0 COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria 57723|Acidobacteria Q Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 PJD2_k127_2982850_3 330214.NIDE2980 6.261e-141 453.0 COG1830@1|root,COG1830@2|Bacteria,3J1DE@40117|Nitrospirae 40117|Nitrospirae G DeoC/LacD family aldolase - - 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - DeoC PJD2_k127_2982850_5 1265505.ATUG01000001_gene3682 1.523e-116 387.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales 28221|Deltaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport PJD2_k127_2982850_7 237368.SCABRO_02054 1.095e-98 336.0 COG0560@1|root,COG0560@2|Bacteria,2J2N0@203682|Planctomycetes 203682|Planctomycetes ET ACT domain - - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - ACT_6,HAD PJD2_k127_2982850_8 554065.XP_005849456.1 4.643e-85 304.0 COG0616@1|root,2QQH5@2759|Eukaryota,37JSU@33090|Viridiplantae,34JKR@3041|Chlorophyta 3041|Chlorophyta OU protease IV - - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 PJD2_k127_2982850_11 373994.Riv7116_1621 8.451e-13 77.0 2BV24@1|root,32QEZ@2|Bacteria,1G6XJ@1117|Cyanobacteria,1HSKI@1161|Nostocales 1117|Cyanobacteria S TIGRFAM PEP-CTERM protein sorting domain - - - - - - - - - - - - - PJD2_k127_2982850_1 460265.Mnod_3292 5.383e-179 569.0 COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,2VGDJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Radical SAM superfamily - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM PJD2_k127_2982850_9 1157490.EL26_09010 5.156e-58 210.0 COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,279PY@186823|Alicyclobacillaceae 91061|Bacilli S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct PJD2_k127_2982850_10 439235.Dalk_1645 9.516e-51 203.0 COG5276@1|root,COG5276@2|Bacteria,1PE5R@1224|Proteobacteria,4375P@68525|delta/epsilon subdivisions,2X232@28221|Deltaproteobacteria,2MM6B@213118|Desulfobacterales 28221|Deltaproteobacteria S LVIVD repeat - - - - - - - - - - - - LVIVD PJD2_k127_2982850_0 243090.RB2114 0.0 1165.0 COG1048@1|root,COG1048@2|Bacteria,2IY29@203682|Planctomycetes 203682|Planctomycetes C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C PJD2_k127_2982850_4 984262.SGRA_p0040 4.007e-125 408.0 COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes 976|Bacteroidetes I Dehydrogenase paaH - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N PJD2_k127_3028884_1 63737.Npun_R2269 1.024e-41 161.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF,HAMP,PAS_3,Zn_Tnp_IS1595,dCache_1 PJD2_k127_3028884_0 745411.B3C1_10727 1.985e-201 649.0 COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1J8W5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S oligopeptide transporter - - - - - - - - - - - - OPT PJD2_k127_3028884_2 1185876.BN8_04980 2.756e-10 68.0 COG5649@1|root,COG5649@2|Bacteria,4NPG5@976|Bacteroidetes,47WXQ@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 PJD2_k127_3054421_2 1316927.ATKI01000116_gene3579 2.45e-19 91.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1YP9G@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria I carboxylase mccA - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 PJD2_k127_3054421_3 584708.Apau_0408 4.422e-15 83.0 COG4770@1|root,COG4770@2|Bacteria,3TBAA@508458|Synergistetes 508458|Synergistetes I Biotin carboxyl carrier protein - - - - - - - - - - - - Biotin_lipoyl PJD2_k127_3054421_1 42256.RradSPS_1222 1.083e-63 229.0 COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CQ84@84995|Rubrobacteria 84995|Rubrobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin - - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA PJD2_k127_3054421_0 479434.Sthe_2336 2.766e-78 265.0 COG2258@1|root,COG2258@2|Bacteria,2G7HE@200795|Chloroflexi,27YRB@189775|Thermomicrobia 189775|Thermomicrobia S MOSC domain - - - - - - - - - - - - MOSC PJD2_k127_3054421_4 1007103.AFHW01000032_gene2246 1.373e-08 58.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 PJD2_k127_3073927_4 926560.KE387023_gene1640 2.342e-21 106.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K12516 - - - - ko00000,ko02000,ko02044 1.B.12.5.5 - - SdrD_B PJD2_k127_3073927_1 903818.KI912269_gene158 3.482e-139 456.0 COG0507@1|root,COG0551@1|root,COG0507@2|Bacteria,COG0551@2|Bacteria 2|Bacteria L DNA topological change helD - 3.6.4.12,5.99.1.2 ko:K03168,ko:K03658 - - - - ko00000,ko01000,ko03032,ko03400 - - - HRDC,HTH_40,Herpes_Helicase,PIF1,TPR_8,UvrD-helicase,UvrD_C,UvrD_C_2,zf-C4_Topoisom PJD2_k127_3073927_5 1191523.MROS_1361 1.826e-14 89.0 COG3420@1|root,COG3420@2|Bacteria 2|Bacteria P alginic acid biosynthetic process - - 4.2.2.3 ko:K01729 ko00051,map00051 - R03706 - ko00000,ko00001,ko01000 - - - Chondroitinas_B PJD2_k127_3073927_3 382464.ABSI01000011_gene2473 6.779e-33 149.0 COG0028@1|root,COG1404@1|root,COG2885@1|root,COG3210@1|root,COG3291@1|root,COG3391@1|root,COG3507@1|root,COG4733@1|root,COG4935@1|root,COG5295@1|root,COG0028@2|Bacteria,COG1404@2|Bacteria,COG2885@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3507@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,COG5295@2|Bacteria,46W6Z@74201|Verrucomicrobia 2|Bacteria GMOU Fibronectin type 3 domain - - 3.2.1.4,3.4.21.96,4.1.3.1,4.2.2.3 ko:K01179,ko:K01361,ko:K01637,ko:K01729,ko:K09942,ko:K20276 ko00051,ko00500,ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00051,map00500,map00630,map01100,map01110,map01120,map01200,map02024 M00012 R00479,R03706,R06200,R11307,R11308 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - GH5,GH9 - fn3 PJD2_k127_3073927_6 1296415.JACC01000019_gene3757 2.52e-09 72.0 COG2273@1|root,COG3291@1|root,COG4412@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,4NTI4@976|Bacteroidetes,1I7WD@117743|Flavobacteriia,2YKNK@290174|Aquimarina 976|Bacteroidetes G Glycosyl hydrolases family 16 - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Glyco_hydro_16 PJD2_k127_3073927_0 1499967.BAYZ01000104_gene3700 1.45e-158 545.0 COG1082@1|root,COG3291@1|root,COG1082@2|Bacteria,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 5.3.99.11 ko:K06606 ko00562,ko01120,map00562,map01120 - R09952 RC01513 ko00000,ko00001,ko01000 - - - AP_endonuc_2,UnbV_ASPIC,VCBS PJD2_k127_3073927_2 1210884.HG799466_gene12892 1.974e-59 222.0 COG5002@1|root,COG5002@2|Bacteria,2J53G@203682|Planctomycetes 203682|Planctomycetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg PJD2_k127_3093097_3 1125863.JAFN01000001_gene833 2.417e-55 199.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1,ECH_2 PJD2_k127_3093097_7 935948.KE386494_gene229 2.012e-28 122.0 COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,1V9ZW@1239|Firmicutes,249UE@186801|Clostridia,42G3P@68295|Thermoanaerobacterales 186801|Clostridia MT SH3, type 3 domain protein - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - NLPC_P60,SH3_3 PJD2_k127_3093097_8 983544.Lacal_1507 9.257e-27 115.0 COG1510@1|root,COG1510@2|Bacteria,4NQPD@976|Bacteroidetes,1I39Q@117743|Flavobacteriia 976|Bacteroidetes K Belongs to the GbsR family - - - - - - - - - - - - HTH_5,MarR_2,TrmB PJD2_k127_3093097_6 693986.MOC_5915 5.16e-38 155.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,1JQVR@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt PJD2_k127_3093097_0 1259795.ARJK01000002_gene253 1.039e-287 905.0 COG0021@1|root,COG0021@2|Bacteria,1VS6Q@1239|Firmicutes,24YYA@186801|Clostridia,42I0G@68295|Thermoanaerobacterales 186801|Clostridia G Transketolase, central region - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_N PJD2_k127_3093097_10 1502852.FG94_03180 0.0001669 51.0 COG4758@1|root,COG4758@2|Bacteria,1RFX6@1224|Proteobacteria,2WCSU@28216|Betaproteobacteria,4772Z@75682|Oxalobacteraceae 28216|Betaproteobacteria S membrane - - - - - - - - - - - - - PJD2_k127_3093097_5 1121285.AUFK01000009_gene872 2.143e-39 156.0 COG0572@1|root,COG0572@2|Bacteria,4P0RC@976|Bacteroidetes,1I7D7@117743|Flavobacteriia,3ZRTM@59732|Chryseobacterium 976|Bacteroidetes F Phosphoribulokinase / Uridine kinase family - - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK PJD2_k127_3093097_1 1047013.AQSP01000130_gene1859 4.457e-113 378.0 COG0438@1|root,COG0438@2|Bacteria,2NQFS@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferases group 1 sps GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246 ko:K00696,ko:K13058 ko00500,ko01100,map00500,map01100 - R00766,R08947 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth PJD2_k127_3093097_9 309803.CTN_1804 1.089e-15 78.0 2DNS1@1|root,32YVX@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2905) yrzS - - - - - - - - - - - DUF2905 PJD2_k127_3093097_4 1047013.AQSP01000140_gene2492 3.418e-54 197.0 COG0652@1|root,COG0652@2|Bacteria,2NPIT@2323|unclassified Bacteria 2|Bacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA - 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase PJD2_k127_3093097_2 1125863.JAFN01000001_gene929 1.841e-90 306.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria 28221|Deltaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 PJD2_k127_3101711_0 1267005.KB911265_gene3608 8.631e-291 902.0 COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2TUPJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N PJD2_k127_3101711_3 1089550.ATTH01000001_gene1827 1.366e-88 322.0 COG1186@1|root,COG1186@2|Bacteria,4NJQS@976|Bacteroidetes,1FJSK@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Psort location OuterMembrane, score - - - - - - - - - - - - OMP_b-brl PJD2_k127_3101711_4 1089550.ATTH01000001_gene1826 1.63e-25 119.0 COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - OmpA PJD2_k127_3101711_1 1173024.KI912149_gene6407 5.1e-132 430.0 COG0667@1|root,COG0667@2|Bacteria,1G2QT@1117|Cyanobacteria,1JJBP@1189|Stigonemataceae 1117|Cyanobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red PJD2_k127_3101711_2 290397.Adeh_1209 1.056e-128 440.0 COG0457@1|root,COG4262@1|root,COG0457@2|Bacteria,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,42Q43@68525|delta/epsilon subdivisions,2WKQF@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth PJD2_k127_3140113_0 204669.Acid345_0604 3.835e-170 564.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia 204432|Acidobacteriia KLT Protein kinase domain - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_11,TPR_16,TPR_2,TPR_8 PJD2_k127_3140113_1 644282.Deba_2013 6.001e-70 264.0 COG0745@1|root,COG2203@1|root,COG2206@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria 28221|Deltaproteobacteria T metal-dependent phosphohydrolase HD region - - - - - - - - - - - - GAF_2,GAF_3,GGDEF,HD,Response_reg PJD2_k127_3140113_2 926560.KE387023_gene3593 5.049e-38 154.0 COG3437@1|root,COG3829@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,1WJ3D@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T PFAM HD domain - - - - - - - - - - - - GAF_2,HD_5,PAS_3 PJD2_k127_3173917_2 379066.GAU_1710 1.359e-74 262.0 COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes 142182|Gemmatimonadetes E ArgK protein - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK PJD2_k127_3173917_3 290397.Adeh_4042 8.116e-31 138.0 COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria 28221|Deltaproteobacteria L HNH nucleases - - - - - - - - - - - - HNH PJD2_k127_3173917_5 926556.Echvi_1486 1.312e-05 55.0 COG2312@1|root,COG2312@2|Bacteria 2|Bacteria S response to antibiotic - - - - - - - - - - - - CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD PJD2_k127_3173917_0 1232452.BAIB02000007_gene1594 2.521e-175 574.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,267U0@186813|unclassified Clostridiales 186801|Clostridia L UvrD-like helicase C-terminal domain pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C PJD2_k127_3173917_1 1379698.RBG1_1C00001G0340 7.399e-162 549.0 COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria 2|Bacteria MU WD40-like Beta Propeller Repeat - - - ko:K03641,ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33,2.C.1.2 - - Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2 PJD2_k127_3173917_4 639283.Snov_0830 1.276e-18 100.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,3EYFX@335928|Xanthobacteraceae 28211|Alphaproteobacteria S TamB, inner membrane protein subunit of TAM complex tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB PJD2_k127_3209704_11 1161401.ASJA01000003_gene2976 3.371e-20 103.0 COG2220@1|root,COG2220@2|Bacteria,1RKSI@1224|Proteobacteria,2UNK6@28211|Alphaproteobacteria,43ZNC@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 PJD2_k127_3209704_6 1122176.KB903534_gene2122 1.832e-52 193.0 COG4977@1|root,COG4977@2|Bacteria,4NHHE@976|Bacteroidetes 976|Bacteroidetes K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - - - - - - - - - - DJ-1_PfpI PJD2_k127_3209704_8 1089550.ATTH01000001_gene2333 3.189e-32 141.0 COG1595@1|root,COG1595@2|Bacteria,4PF4G@976|Bacteroidetes,1FK4D@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes K ECF sigma factor - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_3209704_14 187272.Mlg_1635 0.000357 50.0 COG5662@1|root,COG5662@2|Bacteria,1NG37@1224|Proteobacteria,1ST5G@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Putative zinc-finger - - - - - - - - - - - - zf-HC2 PJD2_k127_3209704_12 566466.NOR53_455 1.292e-16 88.0 2EFI3@1|root,339AJ@2|Bacteria,1N96F@1224|Proteobacteria,1SE0P@1236|Gammaproteobacteria,1J9XG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4252) - - - - - - - - - - - - DUF4252 PJD2_k127_3209704_0 1123367.C666_00015 6.207e-290 915.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,2KV81@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM PJD2_k127_3209704_13 269797.Mbar_A1817 4.689e-10 72.0 COG1413@1|root,arCOG02966@2157|Archaea,2Y7RI@28890|Euryarchaeota 28890|Euryarchaeota C PFAM PBS lyase HEAT-like repeat - - - - - - - - - - - - HEAT_2,HEAT_PBS PJD2_k127_3209704_7 1047013.AQSP01000111_gene1689 1.716e-41 160.0 COG1595@1|root,COG1595@2|Bacteria,2NPR9@2323|unclassified Bacteria 2|Bacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_3209704_1 1519464.HY22_05590 8.275e-224 725.0 COG2866@1|root,COG2866@2|Bacteria 2|Bacteria E metallocarboxypeptidase activity - - - ko:K14054 - - - - ko00000 - - - AstE_AspA,Peptidase_M14 PJD2_k127_3209704_5 1123234.AUKI01000013_gene1581 1.672e-55 213.0 COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia 976|Bacteroidetes O Zinc metalloprotease (Elastase) - - - - - - - - - - - - CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3 PJD2_k127_3209704_10 880073.Calab_0921 2.761e-21 108.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 PJD2_k127_3209704_3 1089550.ATTH01000002_gene88 3.071e-103 342.0 COG4555@1|root,COG4555@2|Bacteria,4PNSV@976|Bacteroidetes 976|Bacteroidetes CP ATPases associated with a variety of cellular activities - - 3.6.3.7 ko:K09697 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.115 - - ABC_tran PJD2_k127_3209704_4 1089550.ATTH01000002_gene87 1.26e-99 340.0 COG1668@1|root,COG1668@2|Bacteria,4NMG0@976|Bacteroidetes 976|Bacteroidetes CP ABC-2 family transporter protein - - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - - ABC2_membrane_2,ABC2_membrane_3 PJD2_k127_3209704_2 1265505.ATUG01000002_gene1825 6.319e-134 436.0 COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2MI2R@213118|Desulfobacterales 28221|Deltaproteobacteria L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 PJD2_k127_3258985_1 309807.SRU_0349 7.2e-151 511.0 COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes 976|Bacteroidetes O Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 PJD2_k127_3258985_0 880073.Calab_2889 3.328e-159 528.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NQIQ@2323|unclassified Bacteria 2|Bacteria E X-Pro dipeptidyl-peptidase (S15 family) dpp - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 PJD2_k127_3258985_3 485913.Krac_5625 1.739e-65 233.0 COG0400@1|root,COG0400@2|Bacteria,2G8M6@200795|Chloroflexi 200795|Chloroflexi S Phospholipase/Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 PJD2_k127_3258985_2 690850.Desaf_3294 6.505e-89 305.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2M8MR@213115|Desulfovibrionales 28221|Deltaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE PJD2_k127_3321577_2 986075.CathTA2_3095 5.495e-203 649.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32840 3HCDH,3HCDH_N,ECH_1 PJD2_k127_3321577_4 1157490.EL26_09420 1.171e-148 481.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,279IB@186823|Alicyclobacillaceae 91061|Bacilli I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N PJD2_k127_3321577_1 204669.Acid345_2471 8.683e-206 657.0 COG1960@1|root,COG1960@2|Bacteria,3Y2NA@57723|Acidobacteria,2JII2@204432|Acidobacteriia 204432|Acidobacteriia I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_3321577_5 945713.IALB_3030 5.152e-35 140.0 COG3439@1|root,COG3439@2|Bacteria 2|Bacteria D Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 PJD2_k127_3321577_0 1191523.MROS_2800 2.461e-214 672.0 COG0334@1|root,COG0334@2|Bacteria 2|Bacteria E glutamate dehydrogenase [NAD(P)+] activity gluD GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 ko:K00260,ko:K00261,ko:K00262 ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.gdhA ELFV_dehydrog,ELFV_dehydrog_N PJD2_k127_3321577_3 1499967.BAYZ01000119_gene3216 2.254e-180 582.0 COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria 2|Bacteria G Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - NTP_transf_2,PPDK_N,Response_reg PJD2_k127_3321577_6 926692.AZYG01000040_gene1516 2.546e-13 72.0 COG0574@1|root,COG0574@2|Bacteria,1TW0W@1239|Firmicutes,248VM@186801|Clostridia 186801|Clostridia G Pyruvate phosphate dikinase, PEP pyruvate binding domain - - - - - - - - - - - - PPDK_N PJD2_k127_3347797_4 378806.STAUR_3709 4.042e-31 138.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YV6N@29|Myxococcales 28221|Deltaproteobacteria E Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 PJD2_k127_3347797_2 207559.Dde_0791 2.967e-75 263.0 COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,42QVG@68525|delta/epsilon subdivisions,2WNKA@28221|Deltaproteobacteria,2M9AG@213115|Desulfovibrionales 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA PJD2_k127_3347797_0 1242864.D187_007079 4.621e-181 588.0 COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria 1224|Proteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - PJD2_k127_3347797_1 1123371.ATXH01000009_gene1104 6.923e-128 425.0 COG1109@1|root,COG1109@2|Bacteria,2GHQ7@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV PJD2_k127_3347797_5 1047013.AQSP01000131_gene1835 2.247e-23 115.0 COG1305@1|root,COG1305@2|Bacteria 2|Bacteria E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core PJD2_k127_3347797_3 573413.Spirs_3993 7.412e-36 150.0 COG3677@1|root,COG3677@2|Bacteria 2|Bacteria L transposition, DNA-mediated tnp3503b - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - Transposase_mut PJD2_k127_3347797_6 1410622.JNKY01000010_gene956 1.163e-16 84.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,27NX7@186928|unclassified Lachnospiraceae 186801|Clostridia O Hsp20/alpha crystallin family hsp18 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 PJD2_k127_3363813_7 529709.PYCH_17650 8.405e-31 133.0 COG0438@1|root,arCOG01403@2157|Archaea,2Y3QD@28890|Euryarchaeota,243F7@183968|Thermococci 183968|Thermococci M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 PJD2_k127_3363813_9 292459.STH1367 2.142e-15 88.0 COG0438@1|root,COG0438@2|Bacteria,1U9H8@1239|Firmicutes,24QQY@186801|Clostridia 186801|Clostridia M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 PJD2_k127_3363813_4 314271.RB2654_12229 4.232e-50 197.0 COG0438@1|root,COG0438@2|Bacteria,1R3TV@1224|Proteobacteria,2TUG4@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - - PJD2_k127_3363813_6 545695.TREAZ_0858 2.37e-36 156.0 COG2227@1|root,COG2227@2|Bacteria,2J6CB@203691|Spirochaetes 203691|Spirochaetes H Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_23 PJD2_k127_3363813_0 161156.JQKW01000008_gene453 1.025e-92 324.0 COG2244@1|root,COG2244@2|Bacteria,2GIK9@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt_3,Polysacc_synt_C PJD2_k127_3363813_5 1209989.TepiRe1_1166 1.031e-49 181.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales 186801|Clostridia J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB PJD2_k127_3363813_3 1379698.RBG1_1C00001G0723 2.462e-59 227.0 COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria 2|Bacteria M Ami_3 amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 PJD2_k127_3363813_8 56780.SYN_01917 1.705e-18 93.0 COG5401@1|root,COG5401@2|Bacteria,1Q1JB@1224|Proteobacteria,437B0@68525|delta/epsilon subdivisions,2X2FP@28221|Deltaproteobacteria,2MSEV@213462|Syntrophobacterales 28221|Deltaproteobacteria S Sporulation and spore germination - - - - - - - - - - - - Germane PJD2_k127_3363813_1 443143.GM18_0312 1.755e-87 304.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales 28221|Deltaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - iAF987.Gmet_0547 Asp_Glu_race PJD2_k127_3363813_2 1245471.PCA10_55310 6.761e-82 278.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1YEJT@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C PJD2_k127_3380341_3 118005.AWNK01000011_gene148 1.739e-132 430.0 COG0226@1|root,COG0226@2|Bacteria 2|Bacteria P phosphate ion binding pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 PJD2_k127_3380341_1 118005.AWNK01000011_gene146 2.042e-220 712.0 COG4590@1|root,COG4590@2|Bacteria 2|Bacteria P Binding-protein-dependent transport system inner membrane component pstC - - ko:K02037,ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 PJD2_k127_3380341_2 768670.Calni_1574 3.535e-183 609.0 COG0581@1|root,COG0581@2|Bacteria,2GF63@200930|Deferribacteres 200930|Deferribacteres P TIGRFAM phosphate ABC transporter, inner membrane subunit PstA - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 PJD2_k127_3380341_4 530564.Psta_2976 1.55e-130 424.0 COG1117@1|root,COG1117@2|Bacteria,2IWRV@203682|Planctomycetes 203682|Planctomycetes P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran PJD2_k127_3380341_6 706587.Desti_5065 8.859e-74 256.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales 28221|Deltaproteobacteria K PFAM response regulator receiver - - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C PJD2_k127_3380341_5 357804.Ping_0836 2.153e-117 400.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,2QHI3@267894|Psychromonadaceae 1236|Gammaproteobacteria T histidine kinase A domain protein domain protein phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS_4,PAS_8 PJD2_k127_3380341_7 880072.Desac_2826 6.894e-70 253.0 COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,42U77@68525|delta/epsilon subdivisions,2WQ4R@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Phosphate-selective porin O and P - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P PJD2_k127_3380341_8 338963.Pcar_0659 5.197e-60 214.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,43SH1@69541|Desulfuromonadales 28221|Deltaproteobacteria P PhoU domain phoU - - ko:K02039 - - - - ko00000 - - - PhoU PJD2_k127_3380341_0 379066.GAU_0803 4.721e-253 807.0 COG2091@1|root,COG2091@2|Bacteria,1ZUQA@142182|Gemmatimonadetes 142182|Gemmatimonadetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - - PJD2_k127_3390696_8 526225.Gobs_0913 9.253e-11 65.0 COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4ESJF@85013|Frankiales 201174|Actinobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C PJD2_k127_3390696_1 517418.Ctha_2284 7.726e-107 355.0 COG0462@1|root,COG0462@2|Bacteria,1FD7M@1090|Chlorobi 1090|Chlorobi F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N PJD2_k127_3390696_7 246197.MXAN_5074 4.672e-27 113.0 COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2WQYK@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Could be involved in septation spoVG - - ko:K06412 - - - - ko00000 - - - SpoVG PJD2_k127_3390696_5 1173263.Syn7502_02413 1.3e-47 186.0 COG1947@1|root,COG1947@2|Bacteria,1G0YY@1117|Cyanobacteria,1GZVI@1129|Synechococcus 1117|Cyanobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N PJD2_k127_3390696_0 1379698.RBG1_1C00001G1326 1.474e-164 525.0 COG2006@1|root,COG2006@2|Bacteria,2NPTK@2323|unclassified Bacteria 2|Bacteria C Domain of unknown function (DUF362) - - - - - - - - - - - - DUF362,Fer4 PJD2_k127_3390696_4 316274.Haur_3242 1.234e-64 235.0 COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi,375BE@32061|Chloroflexia 32061|Chloroflexia M PFAM UbiA prenyltransferase - - - - - - - - - - - - UbiA PJD2_k127_3390696_2 400682.PAC_15706214 1.933e-73 278.0 2CZW5@1|root,2SBX5@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - Glycos_transf_4 PJD2_k127_3390696_3 857087.Metme_1196 7.924e-67 239.0 COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,1XE47@135618|Methylococcales 135618|Methylococcales M NAD(P)H-binding - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase PJD2_k127_3390696_6 1316936.K678_15676 6.391e-38 145.0 COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2TU8I@28211|Alphaproteobacteria,2JQNW@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1 PJD2_k127_3402407_1 240015.ACP_0176 8.776e-44 164.0 COG1960@1|root,COG1960@2|Bacteria,3Y2FM@57723|Acidobacteria,2JIVG@204432|Acidobacteriia 204432|Acidobacteriia I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_3402407_0 649747.HMPREF0083_04884 7.421e-124 411.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,26RP3@186822|Paenibacillaceae 91061|Bacilli I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N PJD2_k127_3402407_3 643562.Daes_2869 3.889e-12 80.0 COG0296@1|root,COG0296@2|Bacteria,1NEFK@1224|Proteobacteria,42VRH@68525|delta/epsilon subdivisions,2WRD5@28221|Deltaproteobacteria,2MC6U@213115|Desulfovibrionales 28221|Deltaproteobacteria G PFAM glycoside hydrolase family 13 domain protein - - - - - - - - - - - - AMPK1_CBM PJD2_k127_3402407_2 459349.CLOAM0583 2.375e-20 99.0 COG1404@1|root,COG1470@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,2NREM@2323|unclassified Bacteria 2|Bacteria O Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CARDB,Calx-beta,CarboxypepD_reg,DUF11,FlgD_ig,HYR,PKD,PPC,SLH,VCBS,fn3 PJD2_k127_3416327_0 1382359.JIAL01000001_gene1431 3.537e-128 416.0 COG0476@1|root,COG0476@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia 204432|Acidobacteriia HP PFAM UBA THIF-type NAD FAD binding - - 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF,ThiS PJD2_k127_3416327_1 1379698.RBG1_1C00001G0230 1.32e-76 278.0 COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria 2|Bacteria T Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD PJD2_k127_3416327_2 1278073.MYSTI_04579 1.171e-09 70.0 COG1413@1|root,COG1413@2|Bacteria,1NYRW@1224|Proteobacteria,430VV@68525|delta/epsilon subdivisions,2WVZE@28221|Deltaproteobacteria 28221|Deltaproteobacteria C lyase activity - - - - - - - - - - - - - PJD2_k127_3421170_0 1121459.AQXE01000003_gene1155 2.081e-71 251.0 COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,42R2C@68525|delta/epsilon subdivisions,2WMZ7@28221|Deltaproteobacteria,2MBYC@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 PJD2_k127_3421170_1 926564.KI911693_gene1065 1.186e-22 110.0 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 PJD2_k127_346314_1 880072.Desac_2093 1.283e-65 229.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2MQA2@213462|Syntrophobacterales 28221|Deltaproteobacteria M PFAM DAHP synthetase I kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 PJD2_k127_346314_0 1031288.AXAA01000004_gene1943 2.068e-226 713.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,36DBK@31979|Clostridiaceae 186801|Clostridia F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS01075 CTP_synth_N,GATase PJD2_k127_346314_2 388051.AUFE01000026_gene5158 4.462e-45 169.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,1K2A1@119060|Burkholderiaceae 28216|Betaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 PJD2_k127_3488561_5 195250.CM001776_gene2980 5.069e-20 97.0 COG0365@1|root,COG0365@2|Bacteria,1G0E7@1117|Cyanobacteria,1GZ2X@1129|Synechococcus 1117|Cyanobacteria H Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C PJD2_k127_3488561_4 1121430.JMLG01000002_gene1010 8.544e-41 161.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,261XK@186807|Peptococcaceae 186801|Clostridia D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 PJD2_k127_3488561_2 1231241.Mc24_04695 4.057e-99 336.0 COG0075@1|root,COG0075@2|Bacteria,2GCGI@200918|Thermotogae 200918|Thermotogae E PFAM aminotransferase class V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - - - - - - - - - - Aminotran_5 PJD2_k127_3488561_3 1125863.JAFN01000001_gene1833 1.887e-92 316.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria C D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT PJD2_k127_3488561_0 518766.Rmar_1452 1.567e-131 433.0 COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1FJ5A@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt PJD2_k127_3488561_1 926550.CLDAP_00700 2.138e-99 333.0 COG1171@1|root,COG1171@2|Bacteria,2G6ME@200795|Chloroflexi 200795|Chloroflexi E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP PJD2_k127_3488906_3 378806.STAUR_3074 5.07e-36 151.0 COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria,43A07@68525|delta/epsilon subdivisions,2WYJQ@28221|Deltaproteobacteria,2YWSZ@29|Myxococcales 28221|Deltaproteobacteria CT Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding PJD2_k127_3488906_2 234267.Acid_1446 2.216e-42 160.0 COG3437@1|root,COG3437@2|Bacteria,3Y907@57723|Acidobacteria 57723|Acidobacteria T cheY-homologous receiver domain - - - - - - - - - - - - HD_5,Response_reg PJD2_k127_3488906_0 1121904.ARBP01000001_gene5553 1.344e-133 447.0 COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia 976|Bacteroidetes S RelA SpoT domain protein - - - - - - - - - - - - GTA_TIM PJD2_k127_3488906_6 234267.Acid_7242 7.458e-31 139.0 COG3391@1|root,COG3391@2|Bacteria,3Y2SU@57723|Acidobacteria 57723|Acidobacteria S TIGRFAM 40-residue YVTN family beta-propeller repeat - - - - - - - - - - - - Lactonase PJD2_k127_3488906_7 1101190.ARWB01000001_gene898 0.000159 53.0 2BCV0@1|root,326FP@2|Bacteria,1MYXP@1224|Proteobacteria,2U5PU@28211|Alphaproteobacteria,36YX6@31993|Methylocystaceae 28211|Alphaproteobacteria - - - - - ko:K20326 ko02024,map02024 - - - ko00000,ko00001 - - - Phenol_MetA_deg PJD2_k127_3488906_4 1461577.CCMH01000053_gene768 2.701e-33 131.0 COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the HesB IscA family sufA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn PJD2_k127_3488906_1 1191523.MROS_0609 1.191e-129 424.0 COG0407@1|root,COG0407@2|Bacteria 2|Bacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3734,iSBO_1134.SBO_4018 URO-D PJD2_k127_3488906_5 880073.Calab_3719 2.327e-31 128.0 COG0635@1|root,COG0635@2|Bacteria,2NP4Y@2323|unclassified Bacteria 2|Bacteria H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 HemN_C,Radical_SAM PJD2_k127_3498658_3 880073.Calab_1958 5.051e-06 60.0 COG2208@1|root,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria 2|Bacteria KT COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit rsbU - 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 - - - CHASE2,GAF,GAF_2,HATPase_c_2,SpoIIE PJD2_k127_3498658_1 1089550.ATTH01000001_gene2240 3.609e-214 693.0 COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1FJ5H@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V PJD2_k127_3498658_5 1410613.JNKF01000002_gene1893 0.0009099 51.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia 976|Bacteroidetes S Tetratricopeptide repeat protein - - - - - - - - - - - - TPR_12,TPR_16,TPR_21,TPR_6,TPR_7,TPR_8 PJD2_k127_3498658_2 1260251.SPISAL_03400 4.48e-17 93.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1WWKI@135613|Chromatiales 135613|Chromatiales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_7 PJD2_k127_3498658_0 1379698.RBG1_1C00001G1225 4.26e-216 688.0 COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein S1 rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 ko:K02945,ko:K03527,ko:K12132 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011 - - - S1 PJD2_k127_3501810_0 234267.Acid_7351 1.799e-24 108.0 COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria 57723|Acidobacteria T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_3501810_3 349521.HCH_00763 0.0003357 51.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R4WG@1224|Proteobacteria,1T1FC@1236|Gammaproteobacteria,1XRKH@135619|Oceanospirillales 135619|Oceanospirillales N Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,TSP_3 PJD2_k127_3501810_1 37919.EP51_20635 9.074e-19 94.0 COG5473@1|root,COG5473@2|Bacteria,2GN5K@201174|Actinobacteria,4FWY1@85025|Nocardiaceae 201174|Actinobacteria J Zn-ribbon protein possibly nucleic acid-binding - - - - - - - - - - - - - PJD2_k127_3501810_2 1121104.AQXH01000001_gene1638 4.814e-17 92.0 2E10Y@1|root,32WGY@2|Bacteria,4NTDG@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - PJD2_k127_3516816_0 1192034.CAP_2901 3.791e-173 550.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YU40@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 PJD2_k127_3516816_1 1192034.CAP_2899 1.22e-133 439.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PCA@68525|delta/epsilon subdivisions,2WM39@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N PJD2_k127_3516816_2 880073.Calab_3776 2.255e-59 212.0 COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 PJD2_k127_3527332_46 518766.Rmar_1587 0.0001122 52.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - NTP_transf_5 PJD2_k127_3527332_2 880073.Calab_1578 1.281e-185 598.0 COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria 2|Bacteria V ABC transporter MdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran PJD2_k127_3527332_4 234267.Acid_3848 8.437e-157 514.0 COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria 57723|Acidobacteria V ABC transporter transmembrane - - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran PJD2_k127_3527332_21 639282.DEFDS_1810 6.617e-68 236.0 COG2316@1|root,COG2316@2|Bacteria,2GFCZ@200930|Deferribacteres 200930|Deferribacteres S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD PJD2_k127_3527332_42 903818.KI912268_gene2486 1.808e-05 57.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4,MucBP PJD2_k127_3527332_45 5691.EAN78035 8.807e-05 55.0 2EBPY@1|root,2SHR8@2759|Eukaryota,3XSFA@5653|Kinetoplastida 5653|Kinetoplastida S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 PJD2_k127_3527332_44 383372.Rcas_0148 8.807e-05 55.0 2FHXQ@1|root,349QQ@2|Bacteria,2GBQF@200795|Chloroflexi,37619@32061|Chloroflexia 32061|Chloroflexia S Domain of unknown function (DUF4388) - - - - - - - - - - - - DUF4388 PJD2_k127_3527332_38 1247963.JPHU01000011_gene723 5.232e-15 87.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain chvI GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K14981 ko02020,map02020 M00520 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C PJD2_k127_3527332_40 945713.IALB_2290 2.898e-09 66.0 2AQ71@1|root,31FCR@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_3527332_43 880073.Calab_2214 2.301e-05 58.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - ko:K09800 - - - - ko00000,ko02000 - - - - PJD2_k127_3527332_39 243090.RB3075 5.787e-12 79.0 2EYTK@1|root,33S0U@2|Bacteria,2IYA9@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - Dockerin_1 PJD2_k127_3527332_28 1131269.AQVV01000002_gene1187 3.136e-41 168.0 COG0737@1|root,COG0737@2|Bacteria 2|Bacteria F nucleotide catabolic process mnuA - - - - - - - - - - - 5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH PJD2_k127_3527332_31 701521.PECL_908 1.581e-26 111.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,3F6YN@33958|Lactobacillaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding PJD2_k127_3527332_15 1379698.RBG1_1C00001G0864 1.094e-80 305.0 COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria 2|Bacteria M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - ko:K04744,ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - LptC,OstA,OstA_C PJD2_k127_3527332_24 429009.Adeg_1821 2.152e-56 211.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42FIY@68295|Thermoanaerobacterales 186801|Clostridia G PFAM ROK family protein glcK - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS10220 ROK PJD2_k127_3527332_23 518766.Rmar_2308 1.163e-58 220.0 COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1FJ13@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M PJD2_k127_3527332_13 1379698.RBG1_1C00001G1549 4.714e-102 341.0 COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria 2|Bacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601 Carboxyl_trans PJD2_k127_3527332_32 1125863.JAFN01000001_gene1377 2.41e-26 118.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P3C@68525|delta/epsilon subdivisions,2WJW1@28221|Deltaproteobacteria 28221|Deltaproteobacteria F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 PJD2_k127_3527332_34 138119.DSY3975 2.979e-24 114.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,26220@186807|Peptococcaceae 186801|Clostridia K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 PJD2_k127_3527332_35 338963.Pcar_1913 1.84e-19 100.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,43UNS@69541|Desulfuromonadales 28221|Deltaproteobacteria O Glycoprotease family yeaZ - 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 PJD2_k127_3527332_33 477974.Daud_2016 2.463e-24 108.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae 186801|Clostridia S PFAM Uncharacterised P-loop hydrolase UPF0079 ydiB - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE PJD2_k127_3527332_3 1379698.RBG1_1C00001G1545 1.59e-163 529.0 COG0745@1|root,COG0745@2|Bacteria,2NNXK@2323|unclassified Bacteria 2|Bacteria KT PglZ domain - - - - - - - - - - - - PglZ,Response_reg PJD2_k127_3527332_14 518766.Rmar_1450 3.927e-82 289.0 COG0642@1|root,COG2205@2|Bacteria,4PKGE@976|Bacteroidetes,1FIRF@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain vicK - - - - - - - - - - - HATPase_c,HisKA PJD2_k127_3527332_6 1123371.ATXH01000009_gene1107 1.159e-133 439.0 COG0172@1|root,COG0172@2|Bacteria,2GGY4@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b PJD2_k127_3527332_26 484770.UFO1_0017 1.094e-45 177.0 COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes 909932|Negativicutes H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC PJD2_k127_3527332_25 586416.GZ22_15515 1.442e-46 183.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli 91061|Bacilli M transferase tagO - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 PJD2_k127_3527332_48 1333523.L593_05090 0.0007315 52.0 COG2244@1|root,arCOG02209@2157|Archaea,2XVVS@28890|Euryarchaeota,23UCY@183963|Halobacteria 183963|Halobacteria S Membrane protein involved in the export of O-antigen and teichoic acid - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C PJD2_k127_3527332_8 880073.Calab_0614 1.54e-130 433.0 COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria 2|Bacteria M UDP-N-acetylglucosamine 2-epimerase wecB - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 PJD2_k127_3527332_12 880073.Calab_3419 1.679e-113 382.0 COG1088@1|root,COG1088@2|Bacteria,2NNRC@2323|unclassified Bacteria 2|Bacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 ko:K01710,ko:K12450 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 M00793 R00293,R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3464 GDP_Man_Dehyd PJD2_k127_3527332_19 1220534.B655_0096 2.199e-69 238.0 COG1898@1|root,arCOG04188@2157|Archaea,2XWJQ@28890|Euryarchaeota 28890|Euryarchaeota M dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom PJD2_k127_3527332_5 379066.GAU_2707 7.567e-156 503.0 COG1004@1|root,COG1004@2|Bacteria,1ZTH3@142182|Gemmatimonadetes 142182|Gemmatimonadetes M UDP binding domain - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N PJD2_k127_3527332_18 525904.Tter_1710 2.003e-69 246.0 COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria 2|Bacteria M Polysaccharide biosynthesis protein - - 1.1.1.281 ko:K15856 ko00051,ko00520,map00051,map00520 - R03397,R03399 RC00182 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd PJD2_k127_3527332_9 1047013.AQSP01000138_gene1042 5.617e-129 422.0 COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria 2|Bacteria M Polysaccharide biosynthesis protein wcbK - 1.1.1.281,4.2.1.47 ko:K01711,ko:K15856 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888,R03397,R03399 RC00182,RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd PJD2_k127_3527332_36 880073.Calab_0921 2.261e-19 104.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 PJD2_k127_3527332_22 264732.Moth_0883 8.714e-60 215.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,42G12@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase PJD2_k127_3527332_16 665571.STHERM_c20600 2.882e-78 271.0 COG0167@1|root,COG0167@2|Bacteria,2J610@203691|Spirochaetes 203691|Spirochaetes F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD - 1.3.1.14 ko:K02823,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHODB_Fe-S_bind,DHO_dh,FAD_binding_6 PJD2_k127_3527332_27 443144.GM21_1819 2.818e-41 162.0 COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales 28221|Deltaproteobacteria C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) pyrK - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 PJD2_k127_3527332_37 880073.Calab_3481 7.484e-19 100.0 COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 PJD2_k127_3527332_10 1121472.AQWN01000003_gene1404 2.986e-125 415.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae 186801|Clostridia F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 PJD2_k127_3527332_11 1379698.RBG1_1C00001G1495 2.472e-119 401.0 COG0540@1|root,COG0540@2|Bacteria,2NNPZ@2323|unclassified Bacteria 2|Bacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00608,ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N PJD2_k127_3527332_20 767817.Desgi_3056 8.571e-69 239.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,261GH@186807|Peptococcaceae 186801|Clostridia F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - iHN637.CLJU_RS05275 Pribosyltran PJD2_k127_3527332_41 1459636.NTE_02734 4.458e-09 65.0 arCOG11830@1|root,arCOG11830@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - PJD2_k127_3527332_1 459349.CLOAM0177 4.836e-190 608.0 COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria 2|Bacteria E Formiminotransferase-cyclodeaminase ftcD - 2.1.2.5,4.3.1.4 ko:K00603,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 - R02287,R02302,R03189 RC00165,RC00221,RC00223,RC00688,RC00870 ko00000,ko00001,ko01000,ko03036,ko04147 - - - FTCD,FTCD_C,FTCD_N PJD2_k127_3527332_29 1040989.AWZU01000008_gene3742 2.938e-31 133.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 PJD2_k127_3527332_7 945713.IALB_2433 1.048e-130 433.0 COG0501@1|root,COG0501@2|Bacteria 2|Bacteria O metalloendopeptidase activity htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - DUF3318,Peptidase_M48 PJD2_k127_3527332_17 945713.IALB_2434 8.042e-75 256.0 COG1704@1|root,COG1704@2|Bacteria 2|Bacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA PJD2_k127_3527332_30 945713.IALB_2435 9.668e-27 116.0 COG3809@1|root,COG3809@2|Bacteria 2|Bacteria S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - Rhomboid,zf-TFIIB PJD2_k127_3527332_0 1158338.JNLJ01000001_gene229 5.673e-253 796.0 COG0021@1|root,COG0021@2|Bacteria,2G42N@200783|Aquificae 200783|Aquificae G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N PJD2_k127_3527332_47 391008.Smal_3327 0.0001474 50.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1X3TV@135614|Xanthomonadales 135614|Xanthomonadales M gamma-glutamyltransferase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept PJD2_k127_3562489_7 237368.SCABRO_02580 1.254e-08 58.0 COG0006@1|root,COG0006@2|Bacteria 2|Bacteria E proline dipeptidase activity pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 PJD2_k127_3562489_1 1379698.RBG1_1C00001G1246 1.307e-62 225.0 COG0613@1|root,COG0613@2|Bacteria,2NPEX@2323|unclassified Bacteria 2|Bacteria S DNA polymerase alpha chain like domain - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP PJD2_k127_3562489_6 114615.BRADO3529 1.04e-12 70.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,3JTEU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Redoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA PJD2_k127_3562489_3 1162668.LFE_0432 4.988e-38 144.0 COG1225@1|root,COG1225@2|Bacteria,3J13P@40117|Nitrospirae 40117|Nitrospirae O AhpC/TSA family - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA PJD2_k127_3562489_4 593750.Metfor_1256 2.375e-35 144.0 COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,2N96I@224756|Methanomicrobia 224756|Methanomicrobia H PFAM bifunctional deaminase-reductase domain protein - - 1.1.1.302 ko:K14654 ko00740,ko01100,map00740,map01100 - R09375,R09376 RC00933 ko00000,ko00001,ko01000 - - - RibD_C PJD2_k127_3562489_5 247490.KSU1_D0612 1.106e-15 83.0 COG2210@1|root,COG2210@2|Bacteria,2J3DW@203682|Planctomycetes 203682|Planctomycetes S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 PJD2_k127_3562489_2 796606.BMMGA3_10590 9.295e-52 199.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZCMB@1386|Bacillus 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 PJD2_k127_3562489_8 96561.Dole_2498 0.0008535 47.0 2ECCP@1|root,33IDE@2|Bacteria,1NQFP@1224|Proteobacteria,42XDI@68525|delta/epsilon subdivisions,2WTE0@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_3562489_0 1047013.AQSP01000139_gene2352 1.786e-89 312.0 COG2866@1|root,COG2866@2|Bacteria 2|Bacteria E metallocarboxypeptidase activity - - - ko:K14054 - - - - ko00000 - - - AstE_AspA,Peptidase_M14 PJD2_k127_3572345_2 1410608.JNKX01000023_gene487 4.782e-08 64.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,4AMCC@815|Bacteroidaceae 976|Bacteroidetes T ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y PJD2_k127_3572345_0 671143.DAMO_1573 7.785e-85 291.0 COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria 2|Bacteria E Metallopeptidase family M24 pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Creatinase_N,Peptidase_M24 PJD2_k127_3573224_3 479434.Sthe_1412 6.501e-53 196.0 COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi,27YFZ@189775|Thermomicrobia 189775|Thermomicrobia V ATPases associated with a variety of cellular activities - - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran PJD2_k127_3573224_4 926569.ANT_19400 4.822e-51 191.0 COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi 200795|Chloroflexi O PFAM cytochrome c-type biogenesis protein CcmB ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB PJD2_k127_3573224_2 1499967.BAYZ01000030_gene1163 4.776e-70 245.0 COG0755@1|root,COG0755@2|Bacteria,2NPG8@2323|unclassified Bacteria 2|Bacteria O Cytochrome C assembly protein ccmC GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736 Cytochrom_C_asm PJD2_k127_3573224_0 1191523.MROS_1169 1.362e-169 539.0 COG1506@1|root,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - - - - - - - - - - - PD40,Peptidase_S9 PJD2_k127_3573224_1 330214.NIDE2199 1.481e-70 257.0 COG2206@1|root,COG2206@2|Bacteria,3J14V@40117|Nitrospirae 40117|Nitrospirae T Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - DUF3391,HD PJD2_k127_3573224_6 1379270.AUXF01000006_gene168 7.581e-24 118.0 COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes 142182|Gemmatimonadetes C HEAT repeats - - - - - - - - - - - - HEAT_2 PJD2_k127_3573224_8 1121930.AQXG01000004_gene2828 4.849e-05 48.0 COG2911@1|root,COG2911@2|Bacteria,4PPNA@976|Bacteroidetes 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - PJD2_k127_3573224_7 269799.Gmet_3240 5.731e-22 104.0 COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42TU6@68525|delta/epsilon subdivisions,2WPZ1@28221|Deltaproteobacteria,43VCX@69541|Desulfuromonadales 28221|Deltaproteobacteria K Ferric uptake regulator family - - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR PJD2_k127_3573224_5 1237149.C900_01486 3.634e-29 127.0 COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator, Crp Fnr family - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding PJD2_k127_3586903_3 404380.Gbem_2643 9.088e-96 325.0 COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,43UAB@69541|Desulfuromonadales 28221|Deltaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 PJD2_k127_3586903_2 335543.Sfum_1411 2.241e-117 401.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2MQ6I@213462|Syntrophobacterales 28221|Deltaproteobacteria E PFAM Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 PJD2_k127_3586903_6 649747.HMPREF0083_02617 4.927e-44 168.0 COG0122@1|root,COG0122@2|Bacteria,1V2ZM@1239|Firmicutes,4HJWB@91061|Bacilli,274CK@186822|Paenibacillaceae 91061|Bacilli L HhH-GPD superfamily base excision DNA repair protein - - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD PJD2_k127_3586903_1 945713.IALB_2228 1.087e-143 472.0 COG0471@1|root,COG0471@2|Bacteria 2|Bacteria P metal ion transport sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp PJD2_k127_3586903_0 1123261.AXDW01000024_gene2057 9.762e-174 561.0 COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,1X4D8@135614|Xanthomonadales 135614|Xanthomonadales S aminopeptidase - - - - - - - - - - - - PA,Peptidase_M28 PJD2_k127_3586903_8 926569.ANT_08170 4e-13 83.0 COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi 200795|Chloroflexi V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 PJD2_k127_3586903_9 555088.DealDRAFT_0316 2.76e-09 69.0 COG0842@1|root,COG0842@2|Bacteria,1V8HM@1239|Firmicutes 1239|Firmicutes V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 PJD2_k127_3586903_4 926569.ANT_08150 1.401e-71 252.0 COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran PJD2_k127_3586903_5 335543.Sfum_1153 2.621e-59 214.0 COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42QJY@68525|delta/epsilon subdivisions,2WK0U@28221|Deltaproteobacteria 28221|Deltaproteobacteria J RNA pseudouridylate synthase - - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 PJD2_k127_3586903_7 1245471.PCA10_30630 6.352e-20 97.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria 1236|Gammaproteobacteria FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA PJD2_k127_3617786_6 1379698.RBG1_1C00001G1690 5.988e-12 67.0 COG4796@1|root,COG4796@2|Bacteria 2|Bacteria U Type ii and iii secretion system protein - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - STN,Secretin,Secretin_N PJD2_k127_3617786_1 596151.DesfrDRAFT_0992 8.342e-62 228.0 COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales 28221|Deltaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad PJD2_k127_3617786_5 323848.Nmul_A2355 4.71e-48 193.0 COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2VNYQ@28216|Betaproteobacteria 28216|Betaproteobacteria U pilus assembly protein - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,Response_reg PJD2_k127_3617786_0 443143.GM18_2435 7.091e-165 530.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,43SA4@69541|Desulfuromonadales 28221|Deltaproteobacteria U PFAM type II secretion system protein E - - - ko:K02283,ko:K03609 - - - - ko00000,ko02035,ko02044,ko03036,ko04812 - - - CbiA,FHA,T2SSE PJD2_k127_3617786_2 1121456.ATVA01000014_gene758 2.988e-54 202.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,42QS0@68525|delta/epsilon subdivisions,2WMU6@28221|Deltaproteobacteria,2M8XP@213115|Desulfovibrionales 28221|Deltaproteobacteria U PFAM Type II secretion system F - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF PJD2_k127_3617786_3 76114.ebA3702 3.407e-54 201.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2VIA4@28216|Betaproteobacteria,2M00Z@206389|Rhodocyclales 206389|Rhodocyclales NU Type II secretion system (T2SS), protein F - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF PJD2_k127_3617786_4 945713.IALB_0987 2.78e-50 186.0 COG3040@1|root,COG3040@2|Bacteria 2|Bacteria M lipid binding - - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 PJD2_k127_3617786_7 439496.RBY4I_2105 1.143e-06 58.0 COG1017@1|root,COG1017@2|Bacteria,1RI4G@1224|Proteobacteria,2U9RP@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Globin - - - - - - - - - - - - Globin PJD2_k127_3662859_5 1069080.KB913028_gene778 2.318e-39 153.0 COG2861@1|root,COG2861@2|Bacteria,1V413@1239|Firmicutes,4H49M@909932|Negativicutes 909932|Negativicutes S Divergent polysaccharide deacetylase - - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 PJD2_k127_3662859_2 1158318.ATXC01000001_gene465 3.456e-79 271.0 COG0854@1|root,COG0854@2|Bacteria,2G3M8@200783|Aquificae 200783|Aquificae H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ PJD2_k127_3662859_1 880073.Calab_0027 1.136e-119 408.0 COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG PJD2_k127_3662859_3 1232410.KI421418_gene2299 1.334e-77 270.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales 28221|Deltaproteobacteria U SecD/SecF GG Motif secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG PJD2_k127_3662859_8 1338011.BD94_3093 0.0001533 51.0 COG2839@1|root,COG2839@2|Bacteria,4NNIY@976|Bacteroidetes,1I3ED@117743|Flavobacteriia,34Q3V@308865|Elizabethkingia 976|Bacteroidetes S Protein of unknown function (DUF456) - - - ko:K09793 - - - - ko00000 - - - DUF456 PJD2_k127_3662859_4 1125863.JAFN01000001_gene1651 1.288e-63 252.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria 28221|Deltaproteobacteria T histidine kinase HAMP region domain protein ntrY - 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 PJD2_k127_3662859_6 290397.Adeh_1548 3.548e-27 130.0 COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria,42UFZ@68525|delta/epsilon subdivisions,2WR5D@28221|Deltaproteobacteria 28221|Deltaproteobacteria D cell septum assembly - - - - - - - - - - - - - PJD2_k127_3662859_0 868864.Dester_1024 2.209e-138 464.0 COG1966@1|root,COG1966@2|Bacteria,2G4H1@200783|Aquificae 200783|Aquificae T PFAM Carbon starvation protein CstA cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0008150,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM PJD2_k127_3662859_7 485917.Phep_0206 2.397e-23 107.0 COG1835@1|root,COG1835@2|Bacteria,4NMNZ@976|Bacteroidetes,1IQXU@117747|Sphingobacteriia 976|Bacteroidetes I Domain of unknown function (DUF4153) - - - - - - - - - - - - DUF4153 PJD2_k127_3674760_0 177437.HRM2_09150 4.912e-117 386.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2MI8E@213118|Desulfobacterales 28221|Deltaproteobacteria J Protein of unknown function (DUF933) - - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C PJD2_k127_3674760_1 309801.trd_1791 3.872e-115 383.0 COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi 200795|Chloroflexi J SMART PUA domain containing protein - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM PJD2_k127_3674760_4 1223523.H340_22626 6.03e-76 260.0 COG0778@1|root,COG0778@2|Bacteria,2GPB4@201174|Actinobacteria 201174|Actinobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase PJD2_k127_3674760_2 880073.Calab_2557 1.111e-83 295.0 COG0477@1|root,COG2814@2|Bacteria,2NS3M@2323|unclassified Bacteria 2|Bacteria EGP Transmembrane secretion effector bacE - - - - - - - - - - - MFS_1,MFS_3 PJD2_k127_3674760_5 1304275.C41B8_05113 5.301e-46 171.0 COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1S6HB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CBS domain - - - - - - - - - - - - CBS PJD2_k127_3674760_6 621372.ACIH01000033_gene575 2.752e-23 111.0 COG5528@1|root,COG5528@2|Bacteria,1VW9Q@1239|Firmicutes,4HWSC@91061|Bacilli,26YQB@186822|Paenibacillaceae 91061|Bacilli S Predicted integral membrane protein (DUF2269) - - - - - - - - - - - - DUF2269 PJD2_k127_3674760_3 344747.PM8797T_25576 8.886e-79 271.0 COG0841@1|root,COG0841@2|Bacteria,2IY0K@203682|Planctomycetes 203682|Planctomycetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran PJD2_k127_3679491_5 34007.IT40_16610 1.328e-11 65.0 COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria,2PU71@265|Paracoccus 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase MA20_38145 - - - - - - - - - - - ECH_1 PJD2_k127_3679491_2 859657.RPSI07_mp0049 9.583e-75 269.0 COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,2VM6S@28216|Betaproteobacteria,1K3I3@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family abmB GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 ko:K00019,ko:K07535 ko00072,ko00362,ko00650,ko01100,ko01120,ko01220,map00072,map00362,map00650,map01100,map01120,map01220 M00088,M00540 R01361,R05582 RC00117,RC00154 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 PJD2_k127_3679491_0 1366050.N234_14090 3.817e-301 939.0 COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,1K008@119060|Burkholderiaceae 28216|Betaproteobacteria CH Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA abmA - 1.14.13.40,1.3.1.34 ko:K00219,ko:K09461 ko00627,ko01120,map00627,map01120 - R03998,R03999 RC00244 ko00000,ko00001,ko01000 - - - FAD_binding_3,Oxidored_FMN PJD2_k127_3679491_1 204669.Acid345_2395 2.778e-183 596.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_2,TPR_8 PJD2_k127_3679491_3 1173027.Mic7113_5053 3.262e-30 134.0 2AK27@1|root,31ARV@2|Bacteria,1G9M6@1117|Cyanobacteria,1HD7A@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - PJD2_k127_3679491_4 511.JT27_07200 1.643e-15 90.0 COG0438@1|root,COG0438@2|Bacteria,1RIHZ@1224|Proteobacteria 1224|Proteobacteria M Heparinase II/III-like protein - - - - - - - - - - - - Hepar_II_III,Hepar_II_III_N PJD2_k127_3680860_0 1499967.BAYZ01000186_gene3985 1.063e-196 637.0 COG0749@1|root,COG0749@2|Bacteria,2NNKA@2323|unclassified Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 PJD2_k127_3680860_3 67275.JOAP01000019_gene1386 5.69e-28 121.0 COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria 201174|Actinobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE,GrpB PJD2_k127_3680860_1 868864.Dester_1396 6.191e-116 383.0 COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae 200783|Aquificae J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 PJD2_k127_3680860_2 246194.CHY_2365 1.241e-112 373.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon,tRNA_bind PJD2_k127_3721400_0 123214.PERMA_0871 5.972e-115 383.0 COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae 200783|Aquificae H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate mqnE - 2.5.1.120 ko:K18285 ko00130,ko01110,map00130,map01110 - R10667 RC00021,RC03234 ko00000,ko00001,ko01000 - - - Fer4_14,Radical_SAM PJD2_k127_3752244_2 177437.HRM2_38970 1.77e-75 265.0 COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria,2MJ41@213118|Desulfobacterales 28221|Deltaproteobacteria CP Proton-conducting membrane transporter ehrA-2 - - ko:K12137 - - - - ko00000,ko01000 - - - Proton_antipo_M,Proton_antipo_N PJD2_k127_3752244_1 404589.Anae109_3782 1.58e-95 336.0 COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,42NHI@68525|delta/epsilon subdivisions,2WJ3D@28221|Deltaproteobacteria,2Z0BP@29|Myxococcales 28221|Deltaproteobacteria C NADH dehydrogenase ehrB - - - - - - - - - - iAF987.Gmet_0374,iAF987.Gmet_2600 NADHdh PJD2_k127_3752244_3 575540.Isop_0367 1.31e-47 185.0 COG4237@1|root,COG4237@2|Bacteria,2J10M@203682|Planctomycetes 203682|Planctomycetes C Hydrogenase 4 membrane - - - ko:K12140 - - - - ko00000,ko01000 - - - - PJD2_k127_3752244_0 596151.DesfrDRAFT_2197 7.863e-147 489.0 COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria,2M9BY@213115|Desulfovibrionales 28221|Deltaproteobacteria CP plastoquinone (Complex I) ehrD - - ko:K12141 - - - - ko00000,ko01000 - - - Proton_antipo_M PJD2_k127_3783951_7 449673.BACSTE_00113 7.029e-63 222.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia,4ANUZ@815|Bacteroidaceae 976|Bacteroidetes IQ with different specificities (related to short-chain alcohol fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 PJD2_k127_3783951_6 1462527.CCDM010000002_gene1336 2.202e-73 258.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,23IQ4@182709|Oceanobacillus 91061|Bacilli I Acyl transferase domain fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 PJD2_k127_3783951_3 243231.GSU1601 3.255e-111 369.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,43S1E@69541|Desulfuromonadales 28221|Deltaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH-2 - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C PJD2_k127_3783951_5 671143.DAMO_1438 3.418e-97 328.0 COG0416@1|root,COG0416@2|Bacteria,2NP1H@2323|unclassified Bacteria 2|Bacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 ko:K03621,ko:K21576,ko:K21577 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis PJD2_k127_3783951_16 1232443.BAIA02000032_gene1897 1.255e-13 72.0 COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia 186801|Clostridia J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p PJD2_k127_3783951_15 2754.EH55_07290 7.828e-20 96.0 COG1399@1|root,COG1399@2|Bacteria,3TBKA@508458|Synergistetes 508458|Synergistetes S acr, cog1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 PJD2_k127_3783951_12 1313421.JHBV01000036_gene2460 5.777e-35 141.0 COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia 976|Bacteroidetes F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK PJD2_k127_3783951_2 861299.J421_3278 8.616e-120 392.0 COG0074@1|root,COG0074@2|Bacteria,1ZT20@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA PJD2_k127_3783951_1 861299.J421_3279 2.612e-134 437.0 COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes 142182|Gemmatimonadetes F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA PJD2_k127_3783951_0 880073.Calab_0633 4.48e-186 591.0 COG2403@1|root,COG2403@2|Bacteria,2NNTB@2323|unclassified Bacteria 2|Bacteria S cyclic 2,3-diphosphoglycerate synthetase activity cpgS - - ko:K05716 - - R03298 RC00900 ko00000,ko01000 - - - cobW PJD2_k127_3783951_10 886293.Sinac_6232 1.02e-47 175.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2IY6V@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB PJD2_k127_3783951_13 880073.Calab_2775 9.973e-26 113.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.11.1,4.6.1.1 ko:K01768,ko:K12132 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001 - - - DUF3467 PJD2_k127_3783951_9 656519.Halsa_2132 2.068e-49 187.0 COG1560@1|root,COG1560@2|Bacteria,1TT7A@1239|Firmicutes,24HMK@186801|Clostridia,3WANH@53433|Halanaerobiales 186801|Clostridia M PFAM Bacterial lipid A biosynthesis acyltransferase - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans PJD2_k127_3783951_8 266117.Rxyl_1396 2.662e-58 216.0 COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CQDE@84995|Rubrobacteria 84995|Rubrobacteria LU DNA recombination-mediator protein A - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A PJD2_k127_3783951_4 886293.Sinac_6520 1.454e-102 343.0 COG0536@1|root,COG0536@2|Bacteria,2IX0Z@203682|Planctomycetes 203682|Planctomycetes S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 PJD2_k127_3783951_11 981336.F944_01973 1.183e-46 182.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,3NJTZ@468|Moraxellaceae 1236|Gammaproteobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0053,iSDY_1059.SDY_4064 CTP_transf_like PJD2_k127_3783951_14 429009.Adeg_0116 2.939e-20 100.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,42GVS@68295|Thermoanaerobacterales 186801|Clostridia L Methyltransferase rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 PJD2_k127_3783951_17 56780.SYN_01756 2.121e-13 82.0 COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria 1224|Proteobacteria NU Pilus assembly protein PilX - - - ko:K02673 - - - - ko00000,ko02035,ko02044 - - - PilX_N PJD2_k127_3783951_18 251221.35211154 7.497e-10 71.0 COG2706@1|root,COG2706@2|Bacteria,1GQSX@1117|Cyanobacteria 1117|Cyanobacteria G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - TIG,VCBS PJD2_k127_3800916_8 1173026.Glo7428_3718 1.329e-09 72.0 COG1749@1|root,COG1749@2|Bacteria,1G2ZW@1117|Cyanobacteria 1117|Cyanobacteria N Ig domain protein group 1 domain protein - - - - - - - - - - - - Big_1,DUF4082 PJD2_k127_3800916_6 1123322.KB904677_gene3136 8.299e-22 113.0 COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria 201174|Actinobacteria M 40-residue YVTN family beta-propeller repeat - - - - - - - - - - - - HemolysinCabind,Lactonase,TIG PJD2_k127_3800916_5 459349.CLOAM0583 2.303e-23 118.0 COG1404@1|root,COG1470@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,2NREM@2323|unclassified Bacteria 2|Bacteria O Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CARDB,Calx-beta,CarboxypepD_reg,DUF11,FlgD_ig,HYR,PKD,PPC,SLH,VCBS,fn3 PJD2_k127_3800916_0 502025.Hoch_5294 0.0 1262.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,42M1V@68525|delta/epsilon subdivisions,2WMFC@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Tricorn protease homolog - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ PJD2_k127_3800916_7 580340.Tlie_0287 1.281e-13 74.0 COG2336@1|root,COG2336@2|Bacteria,3TBRR@508458|Synergistetes 508458|Synergistetes T SpoVT / AbrB like domain - - - ko:K07172 - - - - ko00000,ko02048 - - - MazE_antitoxin PJD2_k127_3800916_4 1121468.AUBR01000011_gene2532 1.726e-46 169.0 COG2337@1|root,COG2337@2|Bacteria,1VBXM@1239|Firmicutes,24M9K@186801|Clostridia,42GHA@68295|Thermoanaerobacterales 186801|Clostridia T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin PJD2_k127_3800916_3 1379698.RBG1_1C00001G0608 6.993e-64 238.0 COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N PJD2_k127_3800916_2 518766.Rmar_1363 5.333e-120 398.0 COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes 976|Bacteroidetes M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 PJD2_k127_3800916_1 555079.Toce_1696 8.712e-181 580.0 COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,42FMD@68295|Thermoanaerobacterales 186801|Clostridia G PFAM glycosidase related protein - - - - - - - - - - - - Glyco_hydro_130 PJD2_k127_3806688_1 1047013.AQSP01000111_gene1672 5.028e-56 208.0 COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria 2|Bacteria M pfkB family carbohydrate kinase rfaE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB PJD2_k127_3806688_2 365046.Rta_01890 6.563e-51 194.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,4ACYJ@80864|Comamonadaceae 28216|Betaproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) rfaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 PJD2_k127_3806688_0 1379698.RBG1_1C00001G1033 5.357e-157 517.0 COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria 2|Bacteria V ABC transporter msbA - - ko:K02021,ko:K06147,ko:K06148,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran PJD2_k127_3806688_3 1131269.AQVV01000001_gene1354 1.029e-21 108.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 PJD2_k127_3812184_3 796942.HMPREF9623_00388 1.362e-19 89.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia 186801|Clostridia F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran PJD2_k127_3812184_1 99598.Cal7507_3400 8.825e-63 246.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HK1F@1161|Nostocales 1117|Cyanobacteria S PFAM Tetratricopeptide repeat - - - - - - - - - - - - CHAT,TPR_1,TPR_12,TPR_7,TPR_8 PJD2_k127_3812184_2 1191523.MROS_0520 2.723e-26 111.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - ko:K15125 ko05133,map05133 - - - ko00000,ko00001,ko00536 - - - Porin_2 PJD2_k127_3812184_0 1134445.AJJM01000052_gene2073 2.726e-64 227.0 COG0135@1|root,COG0135@2|Bacteria 2|Bacteria E phosphoribosylanthranilate isomerase activity trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI PJD2_k127_3815501_7 484770.UFO1_2232 1.059e-37 147.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4H20U@909932|Negativicutes 909932|Negativicutes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran PJD2_k127_3815501_1 870967.VIS19158_05188 1.268e-171 550.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XTS9@135623|Vibrionales 135623|Vibrionales U alanine symporter yaaJ - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp PJD2_k127_3815501_5 391625.PPSIR1_09331 1.811e-61 241.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria 2|Bacteria I 3-hydroxyacyl-CoA dehydrogenase paaH GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - iECO103_1326.ECO103_1532,iJN746.PP_3282 3HCDH,3HCDH_N PJD2_k127_3815501_3 768066.HELO_3947 4.388e-74 265.0 COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,1S0V9@1236|Gammaproteobacteria,1XN9H@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the thiolase family - - - - - - - - - - - - Thiolase_C,Thiolase_N PJD2_k127_3815501_6 1121422.AUMW01000012_gene2969 4.138e-46 174.0 COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,261U9@186807|Peptococcaceae 186801|Clostridia C PFAM pyruvate ferredoxin flavodoxin oxidoreductase iorB - 1.2.7.8 ko:K00180 - - - - br01601,ko00000,ko01000 - - - POR PJD2_k127_3815501_0 696281.Desru_3726 1.79e-176 571.0 COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,260MU@186807|Peptococcaceae 186801|Clostridia C Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates iorA - 1.2.7.8 ko:K00179 - - - - br01601,ko00000,ko01000 - - - Fer4,POR_N,TPP_enzyme_C PJD2_k127_3815501_8 1121033.AUCF01000005_gene5222 2.793e-24 113.0 COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,2JPR6@204441|Rhodospirillales 204441|Rhodospirillales H Probable molybdopterin binding domain - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 PJD2_k127_3815501_9 292459.STH2207 2.053e-06 59.0 COG1975@1|root,COG1975@2|Bacteria,1VFRE@1239|Firmicutes,24U4F@186801|Clostridia 186801|Clostridia O XdhC and CoxI family - - - - - - - - - - - - XdhC_CoxI PJD2_k127_3815501_4 485913.Krac_2435 1.7e-65 235.0 COG1319@1|root,COG1319@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrB - 1.3.7.9 ko:K04109 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - CO_deh_flav_C,FAD_binding_5 PJD2_k127_3815501_2 1382306.JNIM01000001_gene1023 1.911e-99 334.0 COG1529@1|root,COG1529@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrA - 1.3.7.9 ko:K04108 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 PJD2_k127_3826353_20 1280001.BAOA01000021_gene720 0.0008731 44.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1XTK4@135623|Vibrionales 1236|Gammaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria - - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 PJD2_k127_3826353_14 1173263.Syn7502_01589 4.073e-31 123.0 COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1H0S0@1129|Synechococcus 1117|Cyanobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 PJD2_k127_3826353_16 525897.Dbac_3417 3.278e-24 104.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,2MCRH@213115|Desulfovibrionales 28221|Deltaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p PJD2_k127_3826353_3 443143.GM18_0137 1.46e-132 443.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales 28221|Deltaproteobacteria J TIGRFAM ribonuclease, Rne Rng family cafA - 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 PJD2_k127_3826353_17 1121423.JONT01000001_gene1931 2.532e-15 88.0 COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,261TK@186807|Peptococcaceae 186801|Clostridia S protein conserved in bacteria (DUF2344) - - - - - - - - - - - - DUF2344 PJD2_k127_3826353_1 1379698.RBG1_1C00001G1211 1.326e-167 538.0 COG0034@1|root,COG0034@2|Bacteria,2NNSY@2323|unclassified Bacteria 2|Bacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran PJD2_k127_3826353_11 1094715.CM001373_gene3315 1.19e-46 178.0 COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,1SVID@1236|Gammaproteobacteria,1JD85@118969|Legionellales 118969|Legionellales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 PJD2_k127_3826353_0 1034943.BN1094_02167 4.52e-169 562.0 COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales 118969|Legionellales F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C PJD2_k127_3826353_2 370438.PTH_2547 7.543e-166 533.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae 186801|Clostridia F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 PJD2_k127_3826353_7 517418.Ctha_2430 2.323e-70 253.0 COG0265@1|root,COG0265@2|Bacteria,1FEK0@1090|Chlorobi 1090|Chlorobi O Trypsin - - - - - - - - - - - - PDZ_2,Trypsin_2 PJD2_k127_3826353_6 502025.Hoch_0010 2.064e-83 284.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,2YTW3@29|Myxococcales 28221|Deltaproteobacteria F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA PJD2_k127_3826353_10 1120973.AQXL01000112_gene1102 5.202e-51 200.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,279KN@186823|Alicyclobacillaceae 91061|Bacilli J tRNA pseudouridine synthase truA - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 PJD2_k127_3826353_19 2045.KR76_19330 1.968e-05 56.0 COG0619@1|root,COG0619@2|Bacteria,2GKHK@201174|Actinobacteria,4DPHW@85009|Propionibacteriales 201174|Actinobacteria P Cobalt transport protein ecfT - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ PJD2_k127_3826353_9 215803.DB30_0743 1.728e-57 224.0 COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales 28221|Deltaproteobacteria M Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - HEAT_2,Pro_isomerase PJD2_k127_3826353_12 1379698.RBG1_1C00001G0634 5.177e-43 173.0 COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria 2|Bacteria F NUDIX domain - - - - - - - - - - - - NUDIX,Nudix_N_2 PJD2_k127_3826353_4 1249627.D779_2374 3.265e-113 379.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1WWIC@135613|Chromatiales 135613|Chromatiales U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF PJD2_k127_3826353_8 1408422.JHYF01000002_gene2402 7.36e-59 220.0 COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,36G1Z@31979|Clostridiaceae 186801|Clostridia J Threonyl alanyl tRNA synthetase SAD alaXL - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD PJD2_k127_3826353_13 497964.CfE428DRAFT_1579 1.372e-35 139.0 COG0853@1|root,COG0853@2|Bacteria,46W3T@74201|Verrucomicrobia 74201|Verrucomicrobia H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox PJD2_k127_3826353_18 596323.HMPREF0554_1897 3.836e-15 88.0 COG4775@1|root,COG4775@2|Bacteria,378TB@32066|Fusobacteria 32066|Fusobacteria M Outer membrane protein, OMP85 family - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA PJD2_k127_3826353_5 861299.J421_5741 3.799e-106 360.0 COG0596@1|root,COG1228@1|root,COG0596@2|Bacteria,COG1228@2|Bacteria,1ZV1H@142182|Gemmatimonadetes 142182|Gemmatimonadetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 PJD2_k127_3826353_15 1396858.Q666_16310 3.709e-30 128.0 COG2913@1|root,COG2913@2|Bacteria,1N44J@1224|Proteobacteria,1SSX3@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SmpA_OmlA PJD2_k127_3841435_0 1121440.AUMA01000008_gene854 9.826e-77 267.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales 28221|Deltaproteobacteria E Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine nifS-1 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 PJD2_k127_3841435_3 886293.Sinac_1592 4.34e-56 201.0 COG2109@1|root,COG2109@2|Bacteria,2IZYA@203682|Planctomycetes 203682|Planctomycetes H ATP:corrinoid adenosyltransferase BtuR/CobO/CobP - - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - CobA_CobO_BtuR PJD2_k127_3841435_6 634498.mru_1497 2.412e-09 69.0 COG1305@1|root,arCOG02488@1|root,arCOG02165@2157|Archaea,arCOG02488@2157|Archaea,2XXMP@28890|Euryarchaeota,23PG0@183925|Methanobacteria 183925|Methanobacteria E PFAM Transglutaminase-like - - - - - - - - - - - - Big_3_5,Transglut_core PJD2_k127_3841435_5 945713.IALB_2722 3.626e-14 76.0 2EGPU@1|root,33AFZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_3841435_1 335543.Sfum_0112 3.698e-64 229.0 COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,42SJ9@68525|delta/epsilon subdivisions,2WPBC@28221|Deltaproteobacteria,2MRQE@213462|Syntrophobacterales 28221|Deltaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 PJD2_k127_3841435_2 580332.Slit_2177 1.306e-56 210.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2VT5I@28216|Betaproteobacteria 28216|Betaproteobacteria S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 PJD2_k127_3841435_4 1121403.AUCV01000002_gene474 4.812e-30 121.0 COG4747@1|root,COG4747@2|Bacteria 2|Bacteria - - hom - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 ko:K00003,ko:K00058,ko:K01754,ko:K04767 ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00017,M00018,M00020,M00570 R00220,R00996,R01513,R01773,R01775 RC00031,RC00087,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3 PJD2_k127_3857245_4 945713.IALB_1643 3.571e-51 194.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - - PJD2_k127_3857245_2 1379698.RBG1_1C00001G1820 1.956e-74 283.0 COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria 2|Bacteria P COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec PJD2_k127_3857245_6 309807.SRU_2841 0.000952 47.0 COG4206@1|root,COG4774@1|root,COG4206@2|Bacteria,COG4774@2|Bacteria,4P258@976|Bacteroidetes,1FJZ8@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec PJD2_k127_3857245_0 1519464.HY22_07185 1.429e-132 431.0 COG4608@1|root,COG4608@2|Bacteria,1FDGY@1090|Chlorobi 1090|Chlorobi P Belongs to the ABC transporter superfamily - - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY PJD2_k127_3857245_1 1293054.HSACCH_00336 2.153e-124 409.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WAG7@53433|Halanaerobiales 186801|Clostridia P TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain - - - ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY PJD2_k127_3857245_3 644282.Deba_1214 8.164e-72 255.0 COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria 28221|Deltaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N PJD2_k127_3857245_5 720555.BATR1942_03330 1.412e-32 130.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,1ZCAV@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components appB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 PJD2_k127_3880764_0 1122603.ATVI01000006_gene58 1.413e-55 206.0 COG0697@1|root,COG0697@2|Bacteria,1R4G2@1224|Proteobacteria,1SF7R@1236|Gammaproteobacteria,1X9B5@135614|Xanthomonadales 135614|Xanthomonadales EG EamA-like transporter family - - - - - - - - - - - - EamA PJD2_k127_3880764_1 880073.Calab_1858 4.508e-11 77.0 COG1361@1|root,COG4447@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - CHU_C,FlgD_ig,TM_helix PJD2_k127_3884448_1 1279009.ADICEAN_01492 3.981e-56 201.0 COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,47PAA@768503|Cytophagia 976|Bacteroidetes V ABC transporter - - - ko:K19340 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC_tran PJD2_k127_3884448_0 1237149.C900_03369 7.556e-125 409.0 COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,47KEF@768503|Cytophagia 976|Bacteroidetes P Periplasmic copper-binding protein (NosD) nosD - - ko:K07218 - - - - ko00000 - - - NosD PJD2_k127_3886987_7 485913.Krac_8040 1.245e-35 151.0 COG2114@1|root,COG2114@2|Bacteria 2|Bacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - DA1-like,GAF,Guanylate_cyc,HAMP,PAS_4,PAS_9,Response_reg,dCache_1 PJD2_k127_3886987_0 314345.SPV1_12555 1.622e-249 786.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria 1224|Proteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - Aldolase_II,adh_short_C2 PJD2_k127_3886987_2 518766.Rmar_0711 7.163e-165 528.0 COG0761@1|root,COG0761@2|Bacteria,4PEGY@976|Bacteroidetes,1FJ40@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C LytB protein - - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB PJD2_k127_3886987_9 1123279.ATUS01000001_gene2029 5.13e-15 81.0 2E3EZ@1|root,32YDW@2|Bacteria,1NFAN@1224|Proteobacteria,1SFXI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_3886987_12 1144319.PMI16_03045 7.671e-08 64.0 COG4319@1|root,COG4319@2|Bacteria,1NCJR@1224|Proteobacteria,2VURJ@28216|Betaproteobacteria,477EQ@75682|Oxalobacteraceae 28216|Betaproteobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 PJD2_k127_3886987_8 1122179.KB890417_gene3209 4.341e-23 114.0 28NZH@1|root,2Z8IS@2|Bacteria,4NF67@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - PJD2_k127_3886987_5 1276920.ADIAG_01351 1.045e-59 219.0 COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria 201174|Actinobacteria F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC PJD2_k127_3886987_11 1157490.EL26_18420 7.11e-14 75.0 COG2350@1|root,COG2350@2|Bacteria,1VJXT@1239|Firmicutes,4HR02@91061|Bacilli 91061|Bacilli S YCII-related domain - - - - - - - - - - - - YCII PJD2_k127_3886987_3 746697.Aeqsu_1519 1.327e-100 339.0 COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia 976|Bacteroidetes C cytochrome C peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG PJD2_k127_3886987_10 1223410.KN050846_gene1958 1.056e-14 84.0 28JFU@1|root,2Z99Q@2|Bacteria,4NJ9K@976|Bacteroidetes,1HYW4@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - PJD2_k127_3886987_4 690850.Desaf_3498 1.25e-64 244.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - ko:K13735 ko05100,map05100 - - - ko00000,ko00001 - - - Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3 PJD2_k127_3886987_6 1121447.JONL01000001_gene808 5.325e-38 161.0 COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42PDM@68525|delta/epsilon subdivisions,2WMKT@28221|Deltaproteobacteria,2M99P@213115|Desulfovibrionales 28221|Deltaproteobacteria M Biotin-lipoyl like - - - - - - - - - - - - HlyD_D23 PJD2_k127_3886987_1 1232410.KI421421_gene3825 9.51e-182 593.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43U53@69541|Desulfuromonadales 28221|Deltaproteobacteria V AcrB/AcrD/AcrF family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran PJD2_k127_3908303_9 1121403.AUCV01000002_gene474 2.945e-10 62.0 COG4747@1|root,COG4747@2|Bacteria 2|Bacteria - - hom - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 ko:K00003,ko:K00058,ko:K01754,ko:K04767 ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00017,M00018,M00020,M00570 R00220,R00996,R01513,R01773,R01775 RC00031,RC00087,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3 PJD2_k127_3908303_4 886293.Sinac_5243 2.13e-131 425.0 COG0115@1|root,COG0115@2|Bacteria,2J2GT@203682|Planctomycetes 203682|Planctomycetes H Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 PJD2_k127_3908303_6 886293.Sinac_5242 8.995e-97 323.0 2C3PP@1|root,2Z954@2|Bacteria,2J2AE@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - PJD2_k127_3908303_11 861299.J421_6027 0.0004057 51.0 2EB5B@1|root,33561@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_3908303_8 697303.Thewi_2592 2.207e-29 133.0 COG0726@1|root,COG4249@1|root,COG0726@2|Bacteria,COG4249@2|Bacteria,1V2Z7@1239|Firmicutes,25B0R@186801|Clostridia,42G6Y@68295|Thermoanaerobacterales 186801|Clostridia G PFAM Polysaccharide deacetylase - - - ko:K11931,ko:K21478 ko02026,map02026 - R03096 RC00010 ko00000,ko00001,ko01000 - - - Polysacc_deac_1,SLH PJD2_k127_3908303_10 1218075.BAYA01000017_gene4625 9.599e-05 55.0 COG0457@1|root,COG0457@2|Bacteria,1RA3P@1224|Proteobacteria,2VRWC@28216|Betaproteobacteria,1K661@119060|Burkholderiaceae 28216|Betaproteobacteria H Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA hmsH - - ko:K11935 ko02026,map02026 - - - ko00000,ko00001 - - - TPR_16,TPR_19 PJD2_k127_3908303_5 983917.RGE_05590 5.581e-131 434.0 COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2VK83@28216|Betaproteobacteria,1KMBQ@119065|unclassified Burkholderiales 28216|Betaproteobacteria M Glycosyltransferase like family 2 hmsR - - ko:K11936 ko02026,map02026 - - - ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 - Glyco_tranf_2_3,Glycos_transf_2 PJD2_k127_3908303_7 1121015.N789_08235 1.776e-48 179.0 COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,1SAKR@1236|Gammaproteobacteria,1XATQ@135614|Xanthomonadales 135614|Xanthomonadales S Tetratricopeptide repeat - - - - - - - - - - - - - PJD2_k127_3908303_0 1121405.dsmv_2629 4.168e-227 715.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2MHYG@213118|Desulfobacterales 28221|Deltaproteobacteria C PFAM malic - - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic PJD2_k127_3908303_1 1232410.KI421412_gene169 5.83e-210 659.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,43SYA@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK PJD2_k127_3908303_3 1122176.KB903550_gene4348 2.903e-140 473.0 COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,1IUVE@117747|Sphingobacteriia 976|Bacteroidetes S Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 PJD2_k127_3908303_2 468059.AUHA01000004_gene2327 7.421e-173 553.0 COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,1IWMM@117747|Sphingobacteriia 976|Bacteroidetes C 4Fe-4S binding domain yccM_2 - - - - - - - - - - - Fer4,Fer4_5,Fer4_7,Fer4_9 PJD2_k127_3911747_1 1191523.MROS_0663 1.925e-73 260.0 COG3358@1|root,COG3358@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 PJD2_k127_3911747_2 1283300.ATXB01000002_gene2888 1.706e-36 148.0 2DP87@1|root,330Z8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_3911747_0 1286632.P278_31260 1.453e-110 370.0 COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1HXC4@117743|Flavobacteriia 976|Bacteroidetes E asparaginase iaaA - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 PJD2_k127_3911747_3 860228.Ccan_13690 3.067e-05 55.0 COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,1HX8F@117743|Flavobacteriia,1ERI4@1016|Capnocytophaga 976|Bacteroidetes S Tetratricopeptide repeat protein - - - - - - - - - - - - TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8 PJD2_k127_3940826_6 858215.Thexy_2404 8.648e-64 227.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,42FPF@68295|Thermoanaerobacterales 186801|Clostridia K Belongs to the ParB family spo0J - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc PJD2_k127_3940826_10 338963.Pcar_2324 2.065e-39 158.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,43SFK@69541|Desulfuromonadales 28221|Deltaproteobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 PJD2_k127_3940826_11 1209989.TepiRe1_2834 3.473e-22 102.0 COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia,42GQS@68295|Thermoanaerobacterales 186801|Clostridia M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin PJD2_k127_3940826_5 391587.KAOT1_06312 8.908e-70 252.0 COG2755@1|root,COG2755@2|Bacteria,4P0MH@976|Bacteroidetes 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 PJD2_k127_3940826_4 316274.Haur_0996 2.698e-108 359.0 COG4301@1|root,COG4301@2|Bacteria,2G81E@200795|Chloroflexi 200795|Chloroflexi S Histidine-specific methyltransferase, SAM-dependent - - - - - - - - - - - - Methyltransf_33 PJD2_k127_3940826_0 1283300.ATXB01000001_gene2252 1.373e-175 559.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1XG2U@135618|Methylococcales 135618|Methylococcales S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase PJD2_k127_3940826_9 1230342.CTM_16076 8.973e-51 186.0 COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,36DJQ@31979|Clostridiaceae 186801|Clostridia E Diaminopropionate ammonia-lyase dpaL - 4.3.1.15 ko:K01751 - - - - ko00000,ko01000 - - - PALP PJD2_k127_3940826_7 552398.HMPREF0866_01146 7.908e-61 218.0 COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,3WHJ2@541000|Ruminococcaceae 186801|Clostridia E Diaminopropionate ammonia-lyase dpaL - 4.3.1.15 ko:K01751 - - - - ko00000,ko01000 - - - PALP PJD2_k127_3940826_1 880073.Calab_2910 1.968e-165 556.0 COG0168@1|root,COG0168@2|Bacteria,2NQH8@2323|unclassified Bacteria 2|Bacteria P Cation transport protein trkH GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - ko:K03498,ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iECDH1ME8569_1439.ECDH1ME8569_1308,iPC815.YPO3762,iSFV_1184.SFV_3651 TrkH PJD2_k127_3940826_2 926550.CLDAP_34630 1.068e-161 525.0 COG0168@1|root,COG0168@2|Bacteria,2G84B@200795|Chloroflexi 200795|Chloroflexi P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH PJD2_k127_3940826_3 926550.CLDAP_34670 4.113e-148 481.0 COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi 200795|Chloroflexi C PFAM TrkA-N domain protein - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N PJD2_k127_3940826_8 1123368.AUIS01000023_gene925 3.385e-57 211.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria 1236|Gammaproteobacteria P antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex PJD2_k127_3940826_12 1196031.ALEG01000008_gene5105 3.462e-06 50.0 COG3526@1|root,COG3526@2|Bacteria,1VKFI@1239|Firmicutes,4HR9S@91061|Bacilli,1ZKKR@1386|Bacillus 91061|Bacilli O Rdx family - - - ko:K07401 - - - - ko00000 - - - Rdx PJD2_k127_3974903_3 283699.D172_0352 3.452e-10 63.0 COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,1S5VV@1236|Gammaproteobacteria,2Q2XX@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria G mannose-6-phosphate isomerase - - - - - - - - - - - - Cupin_2 PJD2_k127_3974903_1 1125863.JAFN01000001_gene3236 2.594e-109 361.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PFAM 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N PJD2_k127_3974903_0 1240350.AMZE01000018_gene1101 2.776e-156 503.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1YW5Z@136845|Pseudomonas putida group 1236|Gammaproteobacteria I Belongs to the thiolase family atoB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N PJD2_k127_3974903_2 1121129.KB903359_gene2543 1.305e-92 310.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,2FR12@200643|Bacteroidia,22WXU@171551|Porphyromonadaceae 976|Bacteroidetes C acyl-CoA dehydrogenase - - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_3979525_1 1131269.AQVV01000002_gene1174 0.0003508 50.0 COG1579@1|root,COG1579@2|Bacteria 2|Bacteria - - CP_0228 - 3.5.4.16 ko:K07164,ko:K22391 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - zf-RING_7 PJD2_k127_3979525_0 1047013.AQSP01000105_gene1443 0.0 1305.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria 2|Bacteria M Tricorn protease C1 domain - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ PJD2_k127_3985879_1 1198114.AciX9_2671 2.944e-16 86.0 COG0824@1|root,COG0824@2|Bacteria,3Y4WZ@57723|Acidobacteria,2JJIE@204432|Acidobacteriia 204432|Acidobacteriia S PFAM thioesterase superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 PJD2_k127_3985879_0 204669.Acid345_2424 2.104e-107 360.0 COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria,2JME1@204432|Acidobacteriia 204432|Acidobacteriia L Helix-hairpin-helix class 2 (Pol1 family) motifs - - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N PJD2_k127_3989314_7 631362.Thi970DRAFT_00652 3.738e-15 83.0 COG3152@1|root,COG3152@2|Bacteria 2|Bacteria L Membrane - - - - - - - - - - - - DUF4352,DUF805 PJD2_k127_3989314_3 1265505.ATUG01000002_gene2404 2.188e-128 414.0 COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,42N2E@68525|delta/epsilon subdivisions,2WJFV@28221|Deltaproteobacteria,2MIP6@213118|Desulfobacterales 28221|Deltaproteobacteria S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24,DUF4339 PJD2_k127_3989314_4 1121405.dsmv_2612 2.049e-126 413.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2MJ2T@213118|Desulfobacterales 28221|Deltaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N PJD2_k127_3989314_0 1121405.dsmv_2611 5.6e-322 1002.0 COG0603@1|root,COG1402@1|root,COG0603@2|Bacteria,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2X9RQ@28221|Deltaproteobacteria,2MPA0@213118|Desulfobacterales 28221|Deltaproteobacteria F Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase PJD2_k127_3989314_2 1121405.dsmv_2609 2.834e-146 489.0 COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,42PSH@68525|delta/epsilon subdivisions,2WJYZ@28221|Deltaproteobacteria,2MIFM@213118|Desulfobacterales 28221|Deltaproteobacteria S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N PJD2_k127_3989314_1 1121405.dsmv_2608 3.484e-155 504.0 COG0498@1|root,COG0498@2|Bacteria 2|Bacteria E threonine synthase activity - - 2.5.1.76,4.2.3.1 ko:K01733,ko:K15527 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,PALP PJD2_k127_3989314_6 1121434.AULY01000011_gene1665 3.126e-41 169.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2WQGI@28221|Deltaproteobacteria,2MBXZ@213115|Desulfovibrionales 28221|Deltaproteobacteria O Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - FKBP_C PJD2_k127_3989314_5 926569.ANT_28890 7.257e-65 233.0 COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi 200795|Chloroflexi EG EamA-like transporter family - - - - - - - - - - - - EamA PJD2_k127_3993813_1 1379698.RBG1_1C00001G1080 1.603e-151 501.0 COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria 2|Bacteria H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 PJD2_k127_3993813_5 646529.Desaci_3264 1.459e-32 144.0 COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,24A8P@186801|Clostridia,262WN@186807|Peptococcaceae 186801|Clostridia K PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,HTH_18 PJD2_k127_3993813_3 497965.Cyan7822_4300 2.739e-67 237.0 COG0639@1|root,COG0639@2|Bacteria,1G4GG@1117|Cyanobacteria,3KGME@43988|Cyanothece 1117|Cyanobacteria T Calcineurin-like phosphoesterase superfamily domain - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos PJD2_k127_3993813_0 102125.Xen7305DRAFT_00045680 1.57e-173 563.0 COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1G0KZ@1117|Cyanobacteria,3VHRD@52604|Pleurocapsales 1117|Cyanobacteria EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia - - - - - - - - - - - - Chorismate_bind PJD2_k127_3993813_4 1163408.UU9_04182 2.452e-61 230.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1X5B9@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - - - - - - - - - - AMP-binding,AMP-binding_C_2 PJD2_k127_3993813_2 1041930.Mtc_0536 3.455e-110 377.0 COG2006@1|root,arCOG02447@2157|Archaea 2157|Archaea S 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - - - - - - - - - - DUF362 PJD2_k127_3999247_0 340177.Cag_0922 1.543e-55 200.0 COG2738@1|root,COG2738@2|Bacteria,1FEE1@1090|Chlorobi 1090|Chlorobi S PFAM peptidase, membrane zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 PJD2_k127_3999247_4 1121904.ARBP01000001_gene5713 3.603e-35 141.0 2E1HF@1|root,32WVJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF3996 PJD2_k127_3999247_3 1125863.JAFN01000001_gene972 4.986e-36 144.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria 28221|Deltaproteobacteria N PFAM OmpA MotB domain protein - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA PJD2_k127_3999247_1 204669.Acid345_3283 1.037e-51 196.0 COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,3Y4K4@57723|Acidobacteria,2JMIM@204432|Acidobacteriia 204432|Acidobacteriia P TrkA-C domain - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_C,TrkA_N PJD2_k127_3999247_2 1408473.JHXO01000009_gene3423 5.865e-46 187.0 COG4775@1|root,COG4775@2|Bacteria,4NR0H@976|Bacteroidetes,2FW6I@200643|Bacteroidia 976|Bacteroidetes M Surface antigen - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA PJD2_k127_403111_5 756883.Halar_2989 1.675e-25 113.0 COG3119@1|root,arCOG02787@2157|Archaea 2157|Archaea P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.1,3.1.6.6 ko:K01130,ko:K01133 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase PJD2_k127_403111_4 314225.ELI_13350 1.017e-68 236.0 COG0110@1|root,COG0110@2|Bacteria,1RDCP@1224|Proteobacteria,2TWW2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep PJD2_k127_403111_1 313612.L8106_17742 2.867e-160 542.0 COG5360@1|root,COG5360@2|Bacteria,1G4V0@1117|Cyanobacteria 1117|Cyanobacteria S Heparinase II/III-like protein - - - - - - - - - - - - Hepar_II_III,Hepar_II_III_N PJD2_k127_403111_2 1379698.RBG1_1C00001G0201 9.848e-135 437.0 COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria 2|Bacteria O ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 PJD2_k127_403111_6 1265505.ATUG01000001_gene4154 2.014e-07 61.0 293WK@1|root,2ZRBR@2|Bacteria,1PBHQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - PJD2_k127_403111_0 595460.RRSWK_07136 9.834e-177 568.0 COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes 203682|Planctomycetes GM PFAM NAD-dependent epimerase dehydratase - - - - - - - - - - - - DUF2867,NAD_binding_10 PJD2_k127_403111_3 439235.Dalk_0661 5.643e-69 258.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIQF@213118|Desulfobacterales 28221|Deltaproteobacteria T response regulator receiver fgrM - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_4049697_3 1191523.MROS_1840 2.937e-26 111.0 COG4359@1|root,COG4359@2|Bacteria 2|Bacteria E L-methionine salvage from methylthioadenosine mtnX - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HAD,Put_Phosphatase PJD2_k127_4049697_2 945713.IALB_1464 5.396e-32 136.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity luxD - 3.2.1.4,4.2.99.18 ko:K01179,ko:K06889,ko:K10773,ko:K15853 ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko03400 - GH5,GH9 - Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9 PJD2_k127_4049697_0 1042156.CXIVA_07520 2.372e-71 254.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,36E02@31979|Clostridiaceae 186801|Clostridia J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus PJD2_k127_4049697_1 756499.Desde_2360 2.464e-68 239.0 COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,260TX@186807|Peptococcaceae 186801|Clostridia S (AIR) carboxylase - - - ko:K06898 - - - - ko00000 - - - AIRC PJD2_k127_405312_1 1303518.CCALI_01925 1.384e-24 105.0 COG0179@1|root,COG0179@2|Bacteria 2|Bacteria Q Fumarylacetoacetate (FAA) hydrolase - - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - DUF2437,FAA_hydrolase PJD2_k127_405312_2 1245475.ANAE01000103_gene1622 9.095e-23 113.0 COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4EIFG@85012|Streptosporangiales 201174|Actinobacteria M Glycosyl transferase 4-like - - 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 PJD2_k127_405312_3 644282.Deba_0361 1.367e-20 104.0 2CG1Y@1|root,32WID@2|Bacteria,1N01A@1224|Proteobacteria,42UK0@68525|delta/epsilon subdivisions,2WQED@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573,PapD-like PJD2_k127_405312_0 1403819.BATR01000117_gene4029 2.024e-44 174.0 COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae 203494|Verrucomicrobiae CO Redoxin - - - - - - - - - - - - AhpC-TSA PJD2_k127_405312_4 335543.Sfum_3060 1.688e-18 95.0 2CC24@1|root,32VJT@2|Bacteria,1N5Y6@1224|Proteobacteria,42UPP@68525|delta/epsilon subdivisions,2WQ6U@28221|Deltaproteobacteria,2MSB1@213462|Syntrophobacterales 28221|Deltaproteobacteria S IMG reference gene - - - - - - - - - - - - DUF1573 PJD2_k127_405312_6 518766.Rmar_1680 1.356e-09 59.0 COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1FIWE@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes HP ThiF family moeZ - 2.7.7.80,2.8.1.11 ko:K21029,ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF PJD2_k127_4064351_5 880073.Calab_2081 2.549e-27 113.0 COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria 2|Bacteria P LVIVD repeat - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - LVIVD PJD2_k127_4064351_7 459349.CLOAM0984 7.563e-20 106.0 COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25 PJD2_k127_4064351_3 1380394.JADL01000023_gene68 1.954e-41 157.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,2JTJ7@204441|Rhodospirillales 204441|Rhodospirillales J RF-1 domain - - - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 PJD2_k127_4064351_0 880073.Calab_3693 4.835e-255 803.0 COG1297@1|root,COG1297@2|Bacteria,2NPP0@2323|unclassified Bacteria 2|Bacteria S OPT oligopeptide transporter protein oliA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - - - - - - - - - - OPT PJD2_k127_4064351_6 234267.Acid_6287 5.305e-26 125.0 COG1404@1|root,COG1470@1|root,COG3506@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,COG3506@2|Bacteria 2|Bacteria M Protein of unknown function (DUF1349) - - - - - - - - - - - - ASH,DUF11,DUF1349,Peptidase_S8,fn3 PJD2_k127_4064351_10 1191523.MROS_2238 2.679e-14 87.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - CBM_6,fn3 PJD2_k127_4064351_11 234267.Acid_6287 2.529e-12 76.0 COG1404@1|root,COG1470@1|root,COG3506@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,COG3506@2|Bacteria 2|Bacteria M Protein of unknown function (DUF1349) - - - - - - - - - - - - ASH,DUF11,DUF1349,Peptidase_S8,fn3 PJD2_k127_4064351_2 234267.Acid_6287 1.587e-43 182.0 COG1404@1|root,COG1470@1|root,COG3506@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,COG3506@2|Bacteria 2|Bacteria M Protein of unknown function (DUF1349) - - - - - - - - - - - - ASH,DUF11,DUF1349,Peptidase_S8,fn3 PJD2_k127_4064351_8 880073.Calab_2081 2.873e-15 90.0 COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria 2|Bacteria P LVIVD repeat - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - LVIVD PJD2_k127_4064351_1 945713.IALB_2167 1.169e-180 578.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - - - - - - - - - - M64_N,Peptidase_M64,VWA PJD2_k127_4064351_9 335543.Sfum_4032 6.571e-15 86.0 COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,42V4M@68525|delta/epsilon subdivisions,2WRKJ@28221|Deltaproteobacteria,2MS4S@213462|Syntrophobacterales 28221|Deltaproteobacteria T anti-sigma regulatory factor - - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 PJD2_k127_4064351_12 370438.PTH_2272 1.201e-11 69.0 COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,25I7G@186801|Clostridia,266C7@186807|Peptococcaceae 186801|Clostridia T STAS domain - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS PJD2_k127_4064351_4 1200792.AKYF01000017_gene5622 1.114e-29 124.0 COG1595@1|root,COG1595@2|Bacteria,1V183@1239|Firmicutes,4IQ36@91061|Bacilli 91061|Bacilli K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_4079777_2 926569.ANT_23280 3.735e-160 518.0 COG0520@1|root,COG0520@2|Bacteria,2G85X@200795|Chloroflexi 200795|Chloroflexi H Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 PJD2_k127_4079777_6 716544.wcw_1736 3.326e-12 77.0 COG0685@1|root,COG0685@2|Bacteria 2|Bacteria E methylenetetrahydrofolate reductase (NAD(P)H) activity - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,MTHFR_C PJD2_k127_4079777_1 1123368.AUIS01000031_gene1431 1.936e-178 571.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Serine-pyruvate aminotransferase archaeal aspartate aminotransferase pucG - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 PJD2_k127_4079777_5 153721.MYP_465 7.215e-46 182.0 COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,47PNV@768503|Cytophagia 976|Bacteroidetes M Surface antigen - - - - - - - - - - - - Bac_surface_Ag PJD2_k127_4079777_4 517418.Ctha_0318 5.035e-108 355.0 COG1131@1|root,COG1131@2|Bacteria,1FDTT@1090|Chlorobi 2|Bacteria V PFAM ABC transporter related - - 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 - - ABC_tran PJD2_k127_4079777_0 517418.Ctha_0317 2.849e-317 994.0 COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria 2|Bacteria - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC_transp_aux PJD2_k127_4079777_3 517418.Ctha_0316 7.227e-146 485.0 COG3266@1|root,COG3266@2|Bacteria 2|Bacteria GM domain, Protein - - - - - - - - - - - - DUF4340,Gln_amidase PJD2_k127_4079777_7 33898.JRHJ01000055_gene5777 7.464e-10 67.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,2GMNT@201174|Actinobacteria 201174|Actinobacteria U Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - Amidohydro_1,Amidohydro_3,PD40,TAT_signal PJD2_k127_4124760_8 394.NGR_c30790 3.243e-27 130.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,4B8T7@82115|Rhizobiaceae 28211|Alphaproteobacteria S protein conserved in bacteria tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB PJD2_k127_4124760_7 945713.IALB_0238 3.387e-32 128.0 COG4274@1|root,COG4274@2|Bacteria 2|Bacteria S GYD domain - - - - - - - - - - - - GYD PJD2_k127_4124760_1 204669.Acid345_0166 7.755e-133 441.0 COG0174@1|root,COG0174@2|Bacteria 2|Bacteria E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N PJD2_k127_4124760_9 765911.Thivi_3935 2.826e-06 61.0 COG3005@1|root,COG3005@2|Bacteria,1N8UB@1224|Proteobacteria,1RSJQ@1236|Gammaproteobacteria,1WWBB@135613|Chromatiales 135613|Chromatiales P Nitrate TMAO reductase, membrane-bound tetraheme cytochrome c subunit - - - - - - - - - - - - Cytochrom_C552,Paired_CXXCH_1 PJD2_k127_4124760_2 880073.Calab_1599 1.03e-130 450.0 COG2864@1|root,COG2864@2|Bacteria,2NNNM@2323|unclassified Bacteria 2|Bacteria C Cytochrome b subunit of formate dehydrogenase-like protein - - - - - - - - - - - - Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB PJD2_k127_4124760_6 1162668.LFE_1500 1.153e-33 138.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Cytochrome_C554,DUF11,SLH PJD2_k127_4124760_0 1191523.MROS_1186 2.809e-152 497.0 COG3005@1|root,COG3005@2|Bacteria 2|Bacteria C denitrification pathway - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 - - - Cytochrom_NNT,Cytochrom_c3_2 PJD2_k127_4124760_5 1379698.RBG1_1C00001G0781 5.639e-47 173.0 COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria 2|Bacteria C Rieske [2Fe-2S] domain petA - 1.10.2.2,1.10.9.1 ko:K00411,ko:K02636,ko:K03886 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - iAF987.Gmet_1922 CytB6-F_Fe-S,Rieske,UCR_Fe-S_N PJD2_k127_4124760_3 1379698.RBG1_1C00001G0780 3.056e-127 416.0 COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria 2|Bacteria C Cytochrome b(N-terminal)/b6/petB petB - - ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B PJD2_k127_4124760_4 1379698.RBG1_1C00001G0779 1.291e-92 333.0 COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria 2|Bacteria C Cytochrome c554 and c-prime - - - ko:K03620 ko02020,map02020 - - - ko00000,ko00001 - - - Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB PJD2_k127_4138213_2 765912.Thimo_2814 6.253e-33 129.0 COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,1S44Q@1236|Gammaproteobacteria,1WY0B@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K07722 - - - - ko00000,ko03000 - - - NikR_C,RHH_1 PJD2_k127_4138213_0 1379698.RBG1_1C00001G0265 1.915e-83 292.0 COG0592@1|root,COG0592@2|Bacteria,2NP7D@2323|unclassified Bacteria 2|Bacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338,ko:K03610 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400,ko04812 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 PJD2_k127_4138213_1 1382305.AZUC01000045_gene1415 2.696e-58 218.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,26DBF@186818|Planococcaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N PJD2_k127_4138213_4 1223545.GS4_01_00500 4.764e-05 52.0 COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4GD9Z@85026|Gordoniaceae 201174|Actinobacteria S Uncharacterised conserved protein (DUF2156) lysX - - - - - - - - - - - DUF2156 PJD2_k127_4138213_5 58344.JOEL01000010_gene5735 0.0001463 55.0 COG5542@1|root,COG5542@2|Bacteria 2|Bacteria O integral membrane protein - - - - - - - - - - - - Mannosyl_trans2 PJD2_k127_4138213_3 1122182.KB903837_gene3717 2.103e-05 57.0 COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria,4DJGS@85008|Micromonosporales 201174|Actinobacteria U WD40-like Beta Propeller Repeat - - - - - - - - - - - - HYR,PD40,VWA PJD2_k127_4154145_3 1254432.SCE1572_34910 1.416e-16 85.0 COG0392@1|root,COG0392@2|Bacteria,1R959@1224|Proteobacteria 1224|Proteobacteria S integral membrane protein - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM PJD2_k127_4154145_1 697281.Mahau_0989 4.49e-41 171.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales 186801|Clostridia KLT Serine threonine protein kinase prkC - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase PJD2_k127_4154145_0 1267535.KB906767_gene1253 3.509e-64 242.0 COG1801@1|root,COG1801@2|Bacteria 2|Bacteria L Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 PJD2_k127_4154145_2 1202768.JROF01000015_gene1059 6.754e-17 91.0 arCOG00567@1|root,arCOG00567@2157|Archaea,2XVU1@28890|Euryarchaeota,23UZV@183963|Halobacteria 183963|Halobacteria M glycosyl transferase family - - - - - - - - - - - - PMT_2 PJD2_k127_4179423_0 944480.ATUV01000001_gene1133 1.172e-42 180.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2M6KU@213113|Desulfurellales 28221|Deltaproteobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N PJD2_k127_4199645_6 1151117.AJLF01000001_gene1095 0.0001073 46.0 COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,243GM@183968|Thermococci 183968|Thermococci J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) - - 5.3.1.23 ko:K03239,ko:K08963 ko00270,ko01100,ko03013,map00270,map01100,map03013 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000,ko03012 - - - IF-2B PJD2_k127_4199645_2 1476583.DEIPH_ctg079orf0126 2.28e-43 169.0 COG0424@1|root,COG0424@2|Bacteria,1WK7N@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus D COG0424 Nucleotide-binding protein implicated in inhibition of septum formation maf - - ko:K06287 - - - - ko00000 - - - Maf PJD2_k127_4199645_1 1231241.Mc24_07834 1.932e-48 177.0 COG1490@1|root,COG1490@2|Bacteria,2GCYQ@200918|Thermotogae 200918|Thermotogae J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase PJD2_k127_4199645_0 1191523.MROS_0746 1.756e-107 370.0 COG0608@1|root,COG0608@2|Bacteria 2|Bacteria L single-stranded DNA 5'-3' exodeoxyribonuclease activity recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 PJD2_k127_4199645_3 479431.Namu_3274 4.573e-30 130.0 COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4ERXW@85013|Frankiales 201174|Actinobacteria GL phosphoglycerate mutase rnhA GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 ko:K02226,ko:K22316 ko00860,ko01100,ko03030,map00860,map01100,map03030 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000,ko03032 - - - His_Phos_1,RVT_3 PJD2_k127_4199645_4 1313301.AUGC01000011_gene1184 1.082e-08 59.0 COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes 976|Bacteroidetes S Zinc ribbon domain - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 PJD2_k127_4222820_7 236814.IX39_10445 1.024e-15 82.0 COG0845@1|root,COG0845@2|Bacteria,4NSWM@976|Bacteroidetes,1I1UM@117743|Flavobacteriia,3ZUID@59732|Chryseobacterium 976|Bacteroidetes M Protein of unknown function (DUF3347) - - - - - - - - - - - - DUF3347 PJD2_k127_4222820_0 1125863.JAFN01000001_gene1438 0.0 1215.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - iAF987.Gmet_1547 ACR_tran PJD2_k127_4222820_8 481448.Minf_0191 9.798e-13 74.0 2CK2Q@1|root,329IJ@2|Bacteria,46ZCM@74201|Verrucomicrobia,37GU0@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - PJD2_k127_4222820_1 1125863.JAFN01000001_gene1462 1.424e-289 908.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC copF - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase,YHS PJD2_k127_4222820_4 671143.DAMO_1514 7.913e-63 228.0 COG1806@1|root,COG1806@2|Bacteria,2NRN6@2323|unclassified Bacteria 2|Bacteria S Kinase/pyrophosphorylase yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase PJD2_k127_4222820_2 666681.M301_1490 4.766e-173 553.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,2KKTT@206350|Nitrosomonadales 206350|Nitrosomonadales J Beta-Casp domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL PJD2_k127_4222820_6 1177928.TH2_18826 1.015e-39 154.0 COG1309@1|root,COG1309@2|Bacteria,1N6WG@1224|Proteobacteria,2UG93@28211|Alphaproteobacteria,2JTG6@204441|Rhodospirillales 204441|Rhodospirillales K Bacterial regulatory proteins, tetR family - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_C_13,TetR_N PJD2_k127_4222820_5 1408433.JHXV01000022_gene3168 2.913e-55 208.0 COG1524@1|root,COG1524@2|Bacteria,4PKSD@976|Bacteroidetes,1IJEH@117743|Flavobacteriia 976|Bacteroidetes S Metalloenzyme superfamily - - - - - - - - - - - - Metalloenzyme,Phosphodiest PJD2_k127_4227320_2 457415.HMPREF1006_00083 1.47e-11 70.0 COG0392@1|root,COG0392@2|Bacteria,3TAD0@508458|Synergistetes 508458|Synergistetes S PFAM Uncharacterised protein family (UPF0104) - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM PJD2_k127_4227320_0 671143.DAMO_0838 2.865e-100 337.0 COG1131@1|root,COG1131@2|Bacteria,2NNKB@2323|unclassified Bacteria 2|Bacteria V AAA domain, putative AbiEii toxin, Type IV TA system ccmA - 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 - - ABC_tran PJD2_k127_4227320_1 1499967.BAYZ01000095_gene4169 1.633e-60 216.0 COG1277@1|root,COG1277@2|Bacteria,2NPGK@2323|unclassified Bacteria 2|Bacteria S ABC-2 family transporter protein yxlG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux PJD2_k127_422848_3 1379698.RBG1_1C00001G1690 5.988e-12 67.0 COG4796@1|root,COG4796@2|Bacteria 2|Bacteria U Type ii and iii secretion system protein - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - STN,Secretin,Secretin_N PJD2_k127_422848_1 596151.DesfrDRAFT_0992 1.924e-60 223.0 COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales 28221|Deltaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad PJD2_k127_422848_2 1120985.AUMI01000014_gene1066 7.249e-48 186.0 COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,4H306@909932|Negativicutes 909932|Negativicutes KTU cheY-homologous receiver domain - - - - - - - - - - - - AAA_31,Response_reg PJD2_k127_422848_0 1502770.JQMG01000001_gene1735 3.704e-168 540.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2VJWJ@28216|Betaproteobacteria,2KM4A@206350|Nitrosomonadales 206350|Nitrosomonadales U Type II/IV secretion system protein - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE PJD2_k127_4274628_5 172088.AUGA01000002_gene6094 7.396e-24 104.0 COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UFPQ@28211|Alphaproteobacteria,3K28A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin PJD2_k127_4274628_0 314230.DSM3645_18256 5.494e-131 440.0 COG0367@1|root,COG0367@2|Bacteria,2IXAI@203682|Planctomycetes 203682|Planctomycetes E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 PJD2_k127_4274628_3 380394.Lferr_0766 2.1e-62 231.0 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,2NDHR@225057|Acidithiobacillales 225057|Acidithiobacillales M glycosyl transferase group 1 - - - - - - - - - - - - Glycos_transf_1 PJD2_k127_4274628_4 215803.DB30_6413 1.048e-58 217.0 COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,42VTI@68525|delta/epsilon subdivisions,2WW2V@28221|Deltaproteobacteria,2YYXY@29|Myxococcales 28221|Deltaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - GSH-S_ATP PJD2_k127_4274628_2 886293.Sinac_2883 4.535e-79 271.0 COG1762@1|root,COG3311@1|root,COG1762@2|Bacteria,COG3311@2|Bacteria,2IZFY@203682|Planctomycetes 203682|Planctomycetes G PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 - - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - HTH_17,PTS_EIIA_2 PJD2_k127_4274628_1 290397.Adeh_3654 1.282e-106 358.0 COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria 28221|Deltaproteobacteria CP PFAM NADH Ubiquinone plastoquinone (complex I) - - - ko:K12137 - - - - ko00000,ko01000 - - - Proton_antipo_M,Proton_antipo_N PJD2_k127_4288520_6 1452536.JARE01000075_gene579 5.531e-12 71.0 COG1366@1|root,COG1366@2|Bacteria,2HSSW@201174|Actinobacteria,4FQBG@85023|Microbacteriaceae 201174|Actinobacteria T STAS domain - - - - - - - - - - - - STAS_2 PJD2_k127_4288520_2 525904.Tter_2796 3.274e-81 294.0 COG0125@1|root,COG0125@2|Bacteria 2|Bacteria F dTDP biosynthetic process tmk - 2.1.1.45,2.7.4.9 ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02094,R02098,R02101 RC00002,RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin PJD2_k127_4288520_5 1230476.C207_02131 2.283e-40 163.0 COG0438@1|root,COG0438@2|Bacteria,1N2J8@1224|Proteobacteria 1224|Proteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_4288520_1 525904.Tter_2794 6.967e-82 286.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_4288520_4 443255.SCLAV_0318 2.002e-57 213.0 COG2357@1|root,COG2357@2|Bacteria,2I30R@201174|Actinobacteria 201174|Actinobacteria S RelA SpoT domain protein - - - - - - - - - - - - - PJD2_k127_4288520_7 96561.Dole_2043 1.826e-11 76.0 COG1800@1|root,COG2885@1|root,COG3420@1|root,COG1800@2|Bacteria,COG2885@2|Bacteria,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales 28221|Deltaproteobacteria P Parallel beta-helix repeats - - - - - - - - - - - - - PJD2_k127_4288520_0 880073.Calab_1714 3.901e-196 629.0 COG2866@1|root,COG2866@2|Bacteria,2NQT6@2323|unclassified Bacteria 2|Bacteria E Zn_pept - - - - - - - - - - - - Peptidase_M14 PJD2_k127_4288520_3 518766.Rmar_2366 1.994e-78 267.0 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1FIKX@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 PJD2_k127_4328446_1 234267.Acid_3432 5.572e-57 220.0 COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria 57723|Acidobacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,GAF_3,SpoIIE PJD2_k127_4328446_0 62928.azo1687 4.32e-283 901.0 COG0744@1|root,COG0744@2|Bacteria,1NRPB@1224|Proteobacteria,2VJ7F@28216|Betaproteobacteria,2KVVR@206389|Rhodocyclales 206389|Rhodocyclales M COG0744 Membrane carboxypeptidase (penicillin-binding protein) - - - - - - - - - - - - Transgly,Transpeptidase PJD2_k127_4359854_9 945713.IALB_1394 4.867e-24 105.0 COG0843@1|root,COG0843@2|Bacteria 2|Bacteria C heme-copper terminal oxidase activity ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 PJD2_k127_4359854_5 1191523.MROS_0039 2.193e-61 221.0 COG1999@1|root,COG1999@2|Bacteria 2|Bacteria M signal sequence binding sco - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC PJD2_k127_4359854_1 237368.SCABRO_00111 3.226e-253 802.0 COG1331@1|root,COG1331@2|Bacteria,2IX0N@203682|Planctomycetes 203682|Planctomycetes O COG1331 Highly conserved protein containing a thioredoxin domain - - - ko:K06888 - - - - ko00000 - - - DsbC,GlcNAc_2-epim,Thioredox_DsbH PJD2_k127_4359854_6 653733.Selin_0436 4.926e-50 196.0 COG3014@1|root,COG3014@2|Bacteria 2|Bacteria S protein conserved in bacteria - - - ko:K09859 - - - - ko00000 - - - - PJD2_k127_4359854_4 59374.Fisuc_1317 5.845e-62 220.0 COG3417@1|root,COG3417@2|Bacteria 2|Bacteria M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) lpoB GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07337,ko:K21008 ko02025,map02025 - - - ko00000,ko00001 - - - LpoB PJD2_k127_4359854_0 331678.Cphamn1_1066 0.0 1065.0 COG0841@1|root,COG0841@2|Bacteria,1FEYE@1090|Chlorobi 1090|Chlorobi V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran PJD2_k127_4359854_3 290512.Paes_1403 8.665e-75 273.0 COG1538@1|root,COG1538@2|Bacteria 2|Bacteria MU efflux transmembrane transporter activity - - - - - - - - - - - - OEP PJD2_k127_4359854_7 666686.B1NLA3E_05355 4.723e-41 159.0 COG1309@1|root,COG1309@2|Bacteria,1V5ME@1239|Firmicutes,4HH1H@91061|Bacilli,1ZRBA@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N,WHG PJD2_k127_4359854_2 1191523.MROS_2726 2.11e-128 418.0 COG1351@1|root,COG1351@2|Bacteria 2|Bacteria F thymidylate synthase (FAD) activity thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 PJD2_k127_4359854_8 1089550.ATTH01000001_gene641 1.23e-39 152.0 COG0578@1|root,COG0578@2|Bacteria,4NEYG@976|Bacteroidetes,1FIT6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C C-terminal domain of alpha-glycerophosphate oxidase glpA - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C PJD2_k127_4429980_1 880073.Calab_1105 2.286e-111 406.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - ko:K17713,ko:K20952 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.33.1 - - Beta-prism_lec,PQQ_2,PQQ_3,Peptidase_S8,Pkinase,VCBS PJD2_k127_4429980_5 330214.NIDE3793 1.051e-37 158.0 29W26@1|root,30HKR@2|Bacteria,3J1BV@40117|Nitrospirae 40117|Nitrospirae - - - - - - - - - - - - - - - PJD2_k127_4429980_2 530564.Psta_3944 5.326e-95 325.0 COG1858@1|root,COG1858@2|Bacteria,2IY7G@203682|Planctomycetes 203682|Planctomycetes C cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C PJD2_k127_4429980_4 1121015.N789_03735 4.707e-49 184.0 COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Amidinotransferase - - 3.5.3.18 ko:K01482 - - - - ko00000,ko01000,ko04147 - - - Amidinotransf PJD2_k127_4429980_0 880074.BARVI_10745 1.078e-138 457.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FNVV@200643|Bacteroidia,22VWR@171551|Porphyromonadaceae 976|Bacteroidetes E Catalyzes the hydrolysis of Xaa-His dipeptides - - - ko:K01270 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 PJD2_k127_4429980_3 1320556.AVBP01000007_gene836 2.98e-52 196.0 COG2520@1|root,COG2520@2|Bacteria,1QZWN@1224|Proteobacteria,2TYG6@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 PJD2_k127_443592_13 1538295.JY96_07310 8.028e-45 167.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,1KKZ9@119065|unclassified Burkholderiales 28216|Betaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II PJD2_k127_443592_7 926550.CLDAP_07310 7.207e-93 334.0 COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi 200795|Chloroflexi E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI PJD2_k127_443592_6 269800.Tfu_1090 3.666e-97 335.0 COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4EIB5@85012|Streptosporangiales 201174|Actinobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2540c Chorismate_synt PJD2_k127_443592_12 1127695.HMPREF9163_00053 1.798e-45 181.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4H2Y2@909932|Negativicutes 909932|Negativicutes E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N PJD2_k127_443592_4 1121468.AUBR01000014_gene2233 2.321e-117 392.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,42ER2@68295|Thermoanaerobacterales 186801|Clostridia E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase PJD2_k127_443592_2 926569.ANT_01870 1.438e-127 416.0 COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi 200795|Chloroflexi E PFAM DAHP synthetase I KDSA - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 PJD2_k127_443592_10 552811.Dehly_0500 1.209e-62 226.0 COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi,34D8X@301297|Dehalococcoidia 301297|Dehalococcoidia E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA PJD2_k127_443592_0 1121468.AUBR01000014_gene2228 2.929e-153 502.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,42EWK@68295|Thermoanaerobacterales 186801|Clostridia E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP PJD2_k127_443592_14 574087.Acear_1867 1.189e-38 155.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3WBXQ@53433|Halanaerobiales 186801|Clostridia E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI PJD2_k127_443592_11 264732.Moth_1339 1.774e-52 197.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,42EQ2@68295|Thermoanaerobacterales 186801|Clostridia E Belongs to the TrpC family trpC - 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS PJD2_k127_443592_5 1125863.JAFN01000001_gene2405 1.075e-97 333.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2495 GATase,Glycos_trans_3N,Glycos_transf_3 PJD2_k127_443592_9 743719.PaelaDRAFT_5752 1.22e-71 248.0 COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae 91061|Bacilli EH with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine pabA - 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase PJD2_k127_443592_1 330214.NIDE2040 2.603e-141 465.0 COG0147@1|root,COG0147@2|Bacteria,3J0FG@40117|Nitrospirae 40117|Nitrospirae EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind PJD2_k127_443592_8 1121104.AQXH01000001_gene1312 2.184e-78 279.0 COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,1IRH5@117747|Sphingobacteriia 976|Bacteroidetes M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 PJD2_k127_443592_3 1379698.RBG1_1C00001G1092 1.126e-125 429.0 COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria 2|Bacteria E Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.4.17.18,3.4.17.22 ko:K05996,ko:K07752 - - - - ko00000,ko01000,ko01002 - - - F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3 PJD2_k127_4477974_0 880073.Calab_1614 4.689e-199 638.0 COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria 2|Bacteria J elongation factor G fusA2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 PJD2_k127_4477974_5 1232437.KL662016_gene1091 3.764e-83 282.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MIE0@213118|Desulfobacterales 28221|Deltaproteobacteria K transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg PJD2_k127_4477974_11 1117315.AHCA01000002_gene3245 6.691e-44 165.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,2Q06K@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC PJD2_k127_4477974_14 1158150.KB906243_gene1762 2.623e-32 136.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales 135613|Chromatiales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N PJD2_k127_4477974_3 1125863.JAFN01000001_gene101 3.828e-122 400.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria 28221|Deltaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N PJD2_k127_4477974_4 768671.ThimaDRAFT_1056 4.352e-90 308.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales 135613|Chromatiales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth PJD2_k127_4477974_19 639030.JHVA01000001_gene1059 2.182e-15 91.0 COG2982@1|root,COG2982@2|Bacteria,3Y2J8@57723|Acidobacteria,2JKPW@204432|Acidobacteriia 204432|Acidobacteriia M Protein involved in outer membrane biogenesis - - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2,DUF748 PJD2_k127_4477974_2 880073.Calab_3729 3.399e-129 423.0 COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria 2|Bacteria J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT PJD2_k127_4477974_16 545695.TREAZ_3376 1.751e-21 97.0 COG1862@1|root,COG1862@2|Bacteria,2J8D6@203691|Spirochaetes 203691|Spirochaetes U Preprotein translocase, YajC subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC PJD2_k127_4477974_12 521045.Kole_0745 3.573e-40 161.0 COG0242@1|root,COG0242@2|Bacteria,2GD55@200918|Thermotogae 200918|Thermotogae J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase PJD2_k127_4477974_7 1207063.P24_09776 6.09e-75 266.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria,2JQJM@204441|Rhodospirillales 204441|Rhodospirillales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N PJD2_k127_4477974_21 953739.SVEN_3632 2.034e-06 58.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria 201174|Actinobacteria KLT serine threonine protein kinase pknB GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase PJD2_k127_4477974_9 1144275.COCOR_06911 2.267e-60 216.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2YURC@29|Myxococcales 28221|Deltaproteobacteria G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim PJD2_k127_4477974_1 1123252.ATZF01000016_gene1649 4.686e-148 481.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,27BFU@186824|Thermoactinomycetaceae 91061|Bacilli U SRP54-type protein, GTPase domain ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB PJD2_k127_4477974_15 880073.Calab_2051 6.085e-29 122.0 COG0228@1|root,COG0228@2|Bacteria,2NPWN@2323|unclassified Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 PJD2_k127_4477974_18 1379281.AVAG01000033_gene484 1.03e-15 80.0 COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MCGN@213115|Desulfovibrionales 28221|Deltaproteobacteria S Belongs to the UPF0109 family - - - ko:K06960 - - - - ko00000 - - - KH_4 PJD2_k127_4477974_17 1280380.KR100_01870 1.102e-18 93.0 COG0806@1|root,COG0806@2|Bacteria,1G5WP@1117|Cyanobacteria,1H08W@1129|Synechococcus 1117|Cyanobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM PJD2_k127_4477974_8 1121090.KB894685_gene3697 1.319e-68 248.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT PJD2_k127_4477974_13 1050202.KB913024_gene2189 1.098e-36 141.0 COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4094C@622450|Actinopolysporales 201174|Actinobacteria J Ribosomal protein L19 rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 PJD2_k127_4477974_10 1226325.HMPREF1548_04477 3.871e-47 178.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,36DHX@31979|Clostridiaceae 186801|Clostridia L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII PJD2_k127_4477974_20 35754.JNYJ01000005_gene5423 1.161e-13 76.0 COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4DEGG@85008|Micromonosporales 201174|Actinobacteria L Belongs to the UPF0102 family yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 PJD2_k127_4477974_22 1120966.AUBU01000018_gene232 2.192e-06 58.0 2BX8Z@1|root,2ZAPF@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_4477974_6 398767.Glov_2372 5.005e-82 280.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales 28221|Deltaproteobacteria NU General secretory system II, protein E domain protein - - - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N PJD2_k127_4506398_8 1297742.A176_00447 4.41e-20 94.0 COG2197@1|root,COG2197@2|Bacteria,1N00U@1224|Proteobacteria,42U4C@68525|delta/epsilon subdivisions,2WQCS@28221|Deltaproteobacteria,2YZ0A@29|Myxococcales 28221|Deltaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg PJD2_k127_4506398_6 1227739.Hsw_2696 1.47e-44 173.0 COG2227@1|root,COG2227@2|Bacteria,4PKW0@976|Bacteroidetes,47PVE@768503|Cytophagia 976|Bacteroidetes H Methyltransferase domain cypM_1 - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 PJD2_k127_4506398_2 443144.GM21_0249 5.364e-66 231.0 COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,42RS2@68525|delta/epsilon subdivisions,2X9GK@28221|Deltaproteobacteria,43W2H@69541|Desulfuromonadales 28221|Deltaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR PJD2_k127_4506398_0 452637.Oter_0981 7.084e-163 526.0 COG2070@1|root,COG2070@2|Bacteria,46UTY@74201|Verrucomicrobia,3K79P@414999|Opitutae 414999|Opitutae C Nitronate monooxygenase - - - - - - - - - - - - NMO PJD2_k127_4506398_5 1234364.AMSF01000010_gene479 2.185e-48 179.0 COG3428@1|root,COG3428@2|Bacteria,1NHMM@1224|Proteobacteria,1T998@1236|Gammaproteobacteria,1XBUQ@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial PH domain - - - - - - - - - - - - bPH_2 PJD2_k127_4506398_7 1121957.ATVL01000006_gene3201 9.395e-34 134.0 COG2259@1|root,COG2259@2|Bacteria,4PB3J@976|Bacteroidetes,47V4B@768503|Cytophagia 976|Bacteroidetes S DoxX - - - - - - - - - - - - DoxX PJD2_k127_4506398_3 1121405.dsmv_0026 8.403e-66 228.0 COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2MJZR@213118|Desulfobacterales 28221|Deltaproteobacteria Q Thioesterase superfamily - - - - - - - - - - - - 4HBT PJD2_k127_4506398_4 324602.Caur_0649 3.389e-54 213.0 COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia 32061|Chloroflexia O PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - Kelch_4,Kelch_5,Peptidase_S8 PJD2_k127_4506398_1 237368.SCABRO_01870 2.127e-145 479.0 COG0043@1|root,COG0043@2|Bacteria,2IYCA@203682|Planctomycetes 203682|Planctomycetes H COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD PJD2_k127_4531376_1 583355.Caka_2799 1.815e-10 74.0 COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,46VP5@74201|Verrucomicrobia,3K8IM@414999|Opitutae 414999|Opitutae O PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - - - - - - - - - - Peptidase_S8 PJD2_k127_4531376_0 880073.Calab_0921 6.134e-19 102.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 PJD2_k127_4536675_8 1242864.D187_007138 2.644e-50 188.0 COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,42PY5@68525|delta/epsilon subdivisions,2WIU8@28221|Deltaproteobacteria,2YVJ5@29|Myxococcales 28221|Deltaproteobacteria M Glycosyl transferases group 1 tuaH - - - - - - - - - - - Glyco_trans_1_4 PJD2_k127_4536675_6 1254432.SCE1572_50895 1.081e-75 271.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2YXW5@29|Myxococcales 28221|Deltaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_4536675_2 448385.sce0886 3.419e-115 382.0 COG0451@1|root,COG0451@2|Bacteria,1Q2AA@1224|Proteobacteria,43F30@68525|delta/epsilon subdivisions,2X36U@28221|Deltaproteobacteria,2YUQH@29|Myxococcales 28221|Deltaproteobacteria GM Polysaccharide biosynthesis protein - - - - - - - - - - - - Epimerase PJD2_k127_4536675_1 1254432.SCE1572_06215 7.889e-122 400.0 COG0673@1|root,COG0673@2|Bacteria,1R8B2@1224|Proteobacteria,4374E@68525|delta/epsilon subdivisions,2X1Z0@28221|Deltaproteobacteria,2YUQT@29|Myxococcales 28221|Deltaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA PJD2_k127_4536675_15 518766.Rmar_2394 1.095e-11 80.0 COG0737@1|root,COG4677@1|root,COG0737@2|Bacteria,COG4677@2|Bacteria,4PNDC@976|Bacteroidetes,1FJX0@1100069|Bacteroidetes Order II. Incertae sedis 2|Bacteria F pectinesterase activity - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - Beta_helix,Lipase_GDSL_2,NosD,Pectate_lyase_3,SBP_bac_8 PJD2_k127_4536675_9 1262449.CP6013_0770 1.691e-42 182.0 COG0457@1|root,COG3266@1|root,COG4676@1|root,COG4870@1|root,COG0457@2|Bacteria,COG3266@2|Bacteria,COG4676@2|Bacteria,COG4870@2|Bacteria,1VDA3@1239|Firmicutes 1239|Firmicutes O Protein conserved in bacteria - - - - - - - - - - - - CarboxypepD_reg,Flg_new,TPR_19 PJD2_k127_4536675_4 247490.KSU1_D0646 3.301e-100 371.0 COG3507@1|root,COG5306@1|root,COG3507@2|Bacteria,COG5306@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 43 family exbB2 - 3.4.14.5 ko:K01278,ko:K03561,ko:K12287 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko02000,ko02044,ko04090,ko04147 1.A.30.2.1 - - DUF2341,Laminin_G_3,MotA_ExbB PJD2_k127_4536675_17 1396141.BATP01000016_gene2780 0.0001578 56.0 COG1075@1|root,COG4099@1|root,COG4625@1|root,COG1075@2|Bacteria,COG4099@2|Bacteria,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - 3.5.4.40 ko:K18286,ko:K20276 ko00130,ko01110,ko02024,map00130,map01110,map02024 - R10695 RC00477 ko00000,ko00001,ko01000 - - - Abhydrolase_8,Big_5,SLH,SWM_repeat PJD2_k127_4536675_12 1121904.ARBP01000011_gene1571 7.831e-30 140.0 COG3507@1|root,COG3507@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.8,4.2.2.10,4.2.2.2 ko:K01181,ko:K19551 ko00040,map00040 - R02361 RC00049,RC00705 ko00000,ko00001,ko01000 - - - CBM_6,CHB_HEX_C_1,Glyco_hydro_11,Laminin_G_3,Pectate_lyase,Polysacc_deac_1,RicinB_lectin_2 PJD2_k127_4536675_14 1122609.AUGT01000008_gene2868 6.603e-23 117.0 COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - 3.2.1.3 ko:K01178,ko:K14645,ko:K18546 ko00500,ko01100,ko02024,map00500,map01100,map02024 - R01790,R01791,R06199 - ko00000,ko00001,ko01000,ko01002,ko03110 - GH15 - Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3 PJD2_k127_4536675_7 1122185.N792_00185 1.278e-64 237.0 COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,1SFW7@1236|Gammaproteobacteria,1X94G@135614|Xanthomonadales 135614|Xanthomonadales S ATP-grasp - - - - - - - - - - - - - PJD2_k127_4536675_13 1134474.O59_000734 8.562e-25 119.0 COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,1RZ5C@1236|Gammaproteobacteria,1FHH5@10|Cellvibrio 1236|Gammaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 PJD2_k127_4536675_0 222534.KB893670_gene3882 2.579e-123 444.0 COG3507@1|root,COG3507@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 43 family - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Glyco_hyd_101C,Glyco_hydro_101,Glyco_hydro_43,NPCBM,NPCBM_assoc,RicinB_lectin_2 PJD2_k127_4536675_10 1262449.CP6013_0770 1.01e-38 169.0 COG0457@1|root,COG3266@1|root,COG4676@1|root,COG4870@1|root,COG0457@2|Bacteria,COG3266@2|Bacteria,COG4676@2|Bacteria,COG4870@2|Bacteria,1VDA3@1239|Firmicutes 1239|Firmicutes O Protein conserved in bacteria - - - - - - - - - - - - CarboxypepD_reg,Flg_new,TPR_19 PJD2_k127_4536675_16 880073.Calab_0035 7.392e-09 70.0 COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - Big_2,FlgD_ig,SLH PJD2_k127_4536675_11 1415778.JQMM01000001_gene306 9.145e-37 155.0 COG0189@1|root,COG0189@2|Bacteria,1N9X5@1224|Proteobacteria,1SINY@1236|Gammaproteobacteria 1236|Gammaproteobacteria HJ Sugar-transfer associated ATP-grasp - - - - - - - - - - - - ATPgrasp_ST PJD2_k127_4536675_3 382464.ABSI01000011_gene2468 6.882e-102 344.0 COG2227@1|root,COG2227@2|Bacteria,46WCZ@74201|Verrucomicrobia 74201|Verrucomicrobia H C-methyltransferase C-terminal domain - - - - - - - - - - - - Methyltransf_14,Methyltransf_23 PJD2_k127_4536675_5 670307.HYPDE_29593 1.118e-76 263.0 COG0500@1|root,COG0500@2|Bacteria,1MVD1@1224|Proteobacteria,2TUKG@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Methyltransferase - - - - - - - - - - - - Methyltransf_13,Methyltransf_14,Methyltransf_23 PJD2_k127_4547699_1 536227.CcarbDRAFT_3544 1.06e-08 61.0 COG0845@1|root,COG0845@2|Bacteria,1V036@1239|Firmicutes,248P9@186801|Clostridia,36GD3@31979|Clostridiaceae 186801|Clostridia M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 PJD2_k127_4547699_0 1499967.BAYZ01000028_gene1227 3.683e-163 543.0 COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria 2|Bacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran PJD2_k127_4547806_2 411466.ACTODO_00564 1.52e-06 61.0 COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,2I66Z@201174|Actinobacteria,4D38B@85005|Actinomycetales 201174|Actinobacteria M SdrD B-like domain - - - - - - - - - - - - DUF11,SdrD_B PJD2_k127_4547806_0 180281.CPCC7001_1125 1.179e-91 312.0 COG0454@1|root,COG0456@2|Bacteria,1G2QV@1117|Cyanobacteria 1117|Cyanobacteria K PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 PJD2_k127_4547806_1 880073.Calab_2401 9.785e-12 66.0 COG2374@1|root,COG2374@2|Bacteria,2NRB5@2323|unclassified Bacteria 2|Bacteria G Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - Endonuclease_1,Exo_endo_phos,FlgD_ig,LTD PJD2_k127_4575029_1 754477.Q7C_2112 1.589e-42 159.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,462DE@72273|Thiotrichales 72273|Thiotrichales M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL PJD2_k127_4575029_4 717231.Flexsi_0633 0.0007236 47.0 COG3264@1|root,COG3264@2|Bacteria,2GFFZ@200930|Deferribacteres 200930|Deferribacteres M Mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix PJD2_k127_4575029_2 443143.GM18_0409 2.16e-09 68.0 COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 3.2.1.78 ko:K01218,ko:K13276 ko00051,ko02024,map00051,map02024 - R01332 RC00467 ko00000,ko00001,ko01000,ko01002,ko03110 - GH26 - CARDB,CHB_HEX_C_1,F5_F8_type_C,Laminin_G_3 PJD2_k127_4575029_0 218284.CCDN010000001_gene1158 5.322e-191 625.0 COG1205@1|root,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,1ZDM5@1386|Bacillus 91061|Bacilli L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C PJD2_k127_4575029_3 1236508.BAKF01000002_gene242 0.0001282 46.0 COG0671@1|root,COG0671@2|Bacteria,4NKUR@976|Bacteroidetes,2FQBW@200643|Bacteroidia 976|Bacteroidetes I PAP2 family - - - - - - - - - - - - OMP_b-brl,PAP2 PJD2_k127_45830_0 926550.CLDAP_34290 3.658e-42 177.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - ASH,Big_3_2,Cadherin-like,Calx-beta,DUF11,DUF4347,DUF4430,DUF915,FTP,HYR,I-set,PQQ_2,PT-HINT,Peptidase_M36,Pro-kuma_activ,RHS_repeat,VCBS PJD2_k127_45830_1 525904.Tter_2278 4.13e-08 66.0 COG0366@1|root,COG3280@1|root,COG4733@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,COG4733@2|Bacteria,2NP2D@2323|unclassified Bacteria 2|Bacteria G Alpha amylase, catalytic domain malQ - 2.4.1.25,3.2.1.133,3.2.1.135,3.2.1.54,3.2.1.78 ko:K00705,ko:K01208,ko:K01218 ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024 - R01332,R02112,R03122,R05196,R11262 RC00049,RC00467 ko00000,ko00001,ko01000 - GH13,GH26,GH77 - AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,CBM_20,Glyco_hydro_77,Malt_amylase_C,SLH,fn3 PJD2_k127_4588478_1 746697.Aeqsu_2061 2.618e-05 56.0 28M01@1|root,2ZAF6@2|Bacteria,4NP76@976|Bacteroidetes,1I0SP@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - PJD2_k127_4588478_0 1210908.HSB1_33340 9.656e-23 112.0 COG3379@1|root,arCOG01377@2157|Archaea,2XUWW@28890|Euryarchaeota,23RZ5@183963|Halobacteria 183963|Halobacteria S type I phosphodiesterase nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_4625871_9 1379281.AVAG01000024_gene1876 2.3e-08 65.0 COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,2MC38@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM YbbR family protein - - - - - - - - - - - - YbbR PJD2_k127_4625871_5 1191523.MROS_0370 4.554e-30 125.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system - - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 PJD2_k127_4625871_10 945713.IALB_1865 1.464e-07 61.0 COG5652@1|root,COG5652@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - VanZ PJD2_k127_4625871_2 702437.HMPREF9432_01751 2.67e-103 354.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4H20Q@909932|Negativicutes 909932|Negativicutes J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His PJD2_k127_4625871_0 335543.Sfum_3302 3.869e-177 572.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2MR5T@213462|Syntrophobacterales 28221|Deltaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon PJD2_k127_4625871_6 880073.Calab_0220 3.861e-22 105.0 COG1652@1|root,COG1652@2|Bacteria,2NRPG@2323|unclassified Bacteria 2|Bacteria S LysM domain - - - - - - - - - - - - DUF4398,LysM,SAM_adeno_trans,Y_phosphatase3 PJD2_k127_4625871_3 1200792.AKYF01000009_gene3249 2.155e-95 324.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,26QID@186822|Paenibacillaceae 91061|Bacilli T Phosphate starvation protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH PJD2_k127_4625871_1 880073.Calab_2813 5.662e-105 368.0 COG1480@1|root,COG1480@2|Bacteria,2NP1K@2323|unclassified Bacteria 2|Bacteria S 7TM receptor with intracellular HD hydrolase yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD PJD2_k127_4625871_7 477974.Daud_2046 9.274e-20 96.0 COG0295@1|root,COG0319@1|root,COG0295@2|Bacteria,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,2620D@186807|Peptococcaceae 186801|Clostridia J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - 3.5.4.5 ko:K01489,ko:K07042 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000,ko03009 - - - UPF0054 PJD2_k127_4625871_4 525904.Tter_0015 1.445e-58 219.0 COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria 2|Bacteria S Transporter associated domain tlyC - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC,DUF21 PJD2_k127_4625871_8 394221.Mmar10_1488 1.817e-11 71.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,43XS6@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF502) MA20_12960 - - - - - - - - - - - DUF502 PJD2_k127_4630467_9 926567.TheveDRAFT_1028 1.02e-05 49.0 COG1520@1|root,COG1520@2|Bacteria,3TB0M@508458|Synergistetes 508458|Synergistetes S PQQ enzyme repeat - - - - - - - - - - - - PQQ_3 PJD2_k127_4630467_7 638301.HMPREF0444_0949 4.822e-14 76.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,27GRQ@186828|Carnobacteriaceae 91061|Bacilli K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD PJD2_k127_4630467_0 1379698.RBG1_1C00001G1656 0.0 1126.0 COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW PJD2_k127_4630467_8 1121015.N789_06540 2.433e-09 64.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1X63Y@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 PJD2_k127_4630467_1 502025.Hoch_4636 2.789e-238 759.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales 28221|Deltaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom PJD2_k127_4630467_3 335541.Swol_0841 7.885e-124 415.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,42JH5@68298|Syntrophomonadaceae 186801|Clostridia J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO - 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA PJD2_k127_4630467_5 562970.Btus_1487 1.143e-60 222.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,2789H@186823|Alicyclobacillaceae 91061|Bacilli D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase PJD2_k127_4630467_4 765914.ThisiDRAFT_2398 9.344e-62 217.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1WVXJ@135613|Chromatiales 135613|Chromatiales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome PJD2_k127_4630467_2 518766.Rmar_1879 2.954e-151 494.0 COG1220@1|root,COG1220@2|Bacteria,4NFI2@976|Bacteroidetes,1FIQI@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small PJD2_k127_4630467_6 555088.DealDRAFT_1840 1.78e-45 179.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,42JN3@68298|Syntrophomonadaceae 186801|Clostridia E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N PJD2_k127_4631563_2 608538.HTH_1303 8.811e-16 79.0 COG0425@1|root,COG0425@2|Bacteria,2G57Z@200783|Aquificae 200783|Aquificae O Belongs to the sulfur carrier protein TusA family - - - - - - - - - - - - TusA PJD2_k127_4631563_0 316067.Geob_2508 3.514e-90 307.0 COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C PJD2_k127_4631563_1 1379698.RBG1_1C00001G0632 2.518e-16 84.0 COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria 2|Bacteria T STAS domain rsbV - - ko:K04749 - - - - ko00000,ko03021 - - - STAS,STAS_2 PJD2_k127_4633138_4 338966.Ppro_2695 6.845e-28 132.0 COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,42RRN@68525|delta/epsilon subdivisions,2WNAY@28221|Deltaproteobacteria 28221|Deltaproteobacteria S IMG reference gene - - - - - - - - - - - - - PJD2_k127_4633138_5 525904.Tter_0083 5.524e-12 79.0 COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2NPK1@2323|unclassified Bacteria 2|Bacteria T Tetratricopeptide repeat - - - - - - - - - - - - HEAT_2,NACHT,SIR2_2,TPR_1,TPR_11,TPR_2,TPR_8 PJD2_k127_4633138_2 237368.SCABRO_01812 1.04e-50 190.0 COG1262@1|root,COG1262@2|Bacteria,2J0WC@203682|Planctomycetes 203682|Planctomycetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase PJD2_k127_4633138_3 357808.RoseRS_1791 2.259e-34 144.0 COG0583@1|root,COG0583@2|Bacteria,2G8H4@200795|Chloroflexi,376TG@32061|Chloroflexia 32061|Chloroflexia K PFAM regulatory protein, LysR - - - - - - - - - - - - HTH_1,LysR_substrate PJD2_k127_4633138_0 1408473.JHXO01000011_gene3210 3.598e-209 675.0 COG0421@1|root,COG0421@2|Bacteria,4NTHI@976|Bacteroidetes 976|Bacteroidetes E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - - PJD2_k127_4633138_1 439481.Aboo_1037 2.899e-54 197.0 COG0420@1|root,arCOG00397@2157|Archaea,2XY1K@28890|Euryarchaeota 28890|Euryarchaeota L DNA repair exonuclease - - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos PJD2_k127_4647553_14 32507.XP_006799607.1 1.508e-05 53.0 COG2120@1|root,KOG3332@2759|Eukaryota,38DPN@33154|Opisthokonta,3BFJQ@33208|Metazoa,3CY7A@33213|Bilateria,48BP4@7711|Chordata,492CJ@7742|Vertebrata,49T87@7898|Actinopterygii 33208|Metazoa M Phosphatidylinositol glycan anchor biosynthesis, class L PIGL GO:0000225,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006497,GO:0006505,GO:0006506,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006661,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009247,GO:0009987,GO:0012505,GO:0016020,GO:0016254,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019538,GO:0019637,GO:0031984,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046467,GO:0046474,GO:0046486,GO:0046488,GO:0071704,GO:0090407,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 3.5.1.89 ko:K03434 ko00563,ko01100,map00563,map01100 M00065 R05917 - ko00000,ko00001,ko00002,ko01000 - - - PIG-L PJD2_k127_4647553_12 1121904.ARBP01000022_gene3481 1.465e-09 64.0 COG2133@1|root,COG4244@1|root,COG2133@2|Bacteria,COG4244@2|Bacteria,4NG6K@976|Bacteroidetes,47K0Y@768503|Cytophagia 976|Bacteroidetes G Protein of unknown function (DUF1549) - - - - - - - - - - - - PSCyt1,PSCyt2,PSD1 PJD2_k127_4647553_1 880073.Calab_2431 2.989e-134 441.0 COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria 2|Bacteria E Peptidase family M20/M25/M40 - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 PJD2_k127_4647553_9 1254432.SCE1572_15035 2.242e-16 89.0 COG1396@1|root,COG1762@1|root,COG1396@2|Bacteria,COG1762@2|Bacteria,1NBG9@1224|Proteobacteria,439HI@68525|delta/epsilon subdivisions,2X4TU@28221|Deltaproteobacteria,2YZKB@29|Myxococcales 28221|Deltaproteobacteria GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - HTH_31,PTS_EIIA_2 PJD2_k127_4647553_7 1242864.D187_007134 2.517e-21 108.0 COG2244@1|root,COG2244@2|Bacteria,1P0EB@1224|Proteobacteria,431IR@68525|delta/epsilon subdivisions,2WW7D@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C PJD2_k127_4647553_4 518766.Rmar_1322 4.522e-62 230.0 COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1FIXH@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_4647553_0 467200.ACFA01000237_gene916 3.72e-152 492.0 COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria 201174|Actinobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family algD - 1.1.1.132 ko:K00066 ko00051,ko00520,ko02020,map00051,map00520,map02020 - R00880 RC00291 ko00000,ko00001,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N PJD2_k127_4647553_10 404380.Gbem_0575 4e-15 81.0 COG2259@1|root,COG2259@2|Bacteria,1NC5I@1224|Proteobacteria,42V27@68525|delta/epsilon subdivisions,2WS2G@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM Methylamine - - - - - - - - - - - - MauE PJD2_k127_4647553_11 96561.Dole_2883 1.44e-13 84.0 COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQHB@28221|Deltaproteobacteria,2MQ0A@213118|Desulfobacterales 28221|Deltaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese PJD2_k127_4647553_2 706587.Desti_4506 8.384e-87 307.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MQER@213462|Syntrophobacterales 28221|Deltaproteobacteria I PFAM Enoyl-CoA hydratase isomerase - - - - - - - - - - - - 3HCDH_N,ECH_1 PJD2_k127_4647553_6 1121405.dsmv_3802 4.864e-44 172.0 COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,43AXT@68525|delta/epsilon subdivisions,2X6BZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_4647553_5 359.CN09_33865 2.923e-50 198.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - ko:K14340 - - - - ko00000,ko01000,ko01003 - - - PMT_2 PJD2_k127_4647553_8 1054217.TALC_01501 1.587e-19 97.0 COG0560@1|root,arCOG01158@2157|Archaea,2Y79H@28890|Euryarchaeota,241UM@183967|Thermoplasmata 183967|Thermoplasmata E haloacid dehalogenase-like hydrolase - - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD PJD2_k127_4647553_3 330214.NIDE3960 4.453e-80 275.0 COG1611@1|root,COG1611@2|Bacteria,3J169@40117|Nitrospirae 40117|Nitrospirae S Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox PJD2_k127_4651172_1 1379698.RBG1_1C00001G1524 2.003e-08 67.0 COG2911@1|root,COG2911@2|Bacteria,2NQ89@2323|unclassified Bacteria 2|Bacteria S TamB, inner membrane protein subunit of TAM complex - - - ko:K07277,ko:K09800 - - - - ko00000,ko02000,ko03029 1.B.33 - - AsmA_2,DUF748,TamB PJD2_k127_4651172_0 880072.Desac_2078 4.328e-49 197.0 COG4775@1|root,COG4775@2|Bacteria,1QX52@1224|Proteobacteria,43CEZ@68525|delta/epsilon subdivisions,2X7PY@28221|Deltaproteobacteria,2MRBQ@213462|Syntrophobacterales 28221|Deltaproteobacteria M Surface antigen - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA PJD2_k127_4659999_1 1254432.SCE1572_03070 0.0 1313.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2YUEA@29|Myxococcales 28221|Deltaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 PJD2_k127_4659999_0 1379698.RBG1_1C00001G1604 0.0 1866.0 COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria 2|Bacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 PJD2_k127_4659999_3 234267.Acid_5123 4.384e-62 217.0 COG0048@1|root,COG0048@2|Bacteria,3Y4JQ@57723|Acidobacteria 57723|Acidobacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 PJD2_k127_4659999_4 945713.IALB_0908 1.672e-58 206.0 COG0049@1|root,COG0049@2|Bacteria 2|Bacteria J rRNA binding rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 PJD2_k127_4659999_2 1128421.JAGA01000002_gene692 3.928e-263 826.0 COG0480@1|root,COG0480@2|Bacteria,2NNSV@2323|unclassified Bacteria 2|Bacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 PJD2_k127_470323_3 644282.Deba_2669 1.583e-24 106.0 COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Bifunctional nuclease - - - ko:K08999 - - - - ko00000 - - - DNase-RNase PJD2_k127_470323_7 1122176.KB903554_gene3803 0.0001605 54.0 COG1729@1|root,COG1729@2|Bacteria 2|Bacteria S protein trimerization - - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - LysM,TPR_16,TPR_6,YfiO PJD2_k127_470323_6 1379698.RBG1_1C00001G0463 4.966e-16 92.0 COG0760@1|root,COG0760@2|Bacteria,2NPFB@2323|unclassified Bacteria 2|Bacteria O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769,ko:K03770,ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 PJD2_k127_470323_0 1191523.MROS_0017 1.327e-92 316.0 COG0836@1|root,COG0836@2|Bacteria 2|Bacteria M mannose-1-phosphate guanylyltransferase activity manC - 2.7.7.13,5.3.1.8,5.4.2.8 ko:K00971,ko:K01840,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01818,R01819 RC00002,RC00376,RC00408 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS00940 MannoseP_isomer,NTP_transferase PJD2_k127_470323_2 880073.Calab_2408 1.284e-39 152.0 COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria 2|Bacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N PJD2_k127_470323_4 1408437.JNJN01000012_gene315 5.84e-23 102.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,25WV7@186806|Eubacteriaceae 186801|Clostridia J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 PJD2_k127_470323_5 1174504.AJTN02000193_gene4155 1.62e-19 93.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,1ZGZ0@1386|Bacillus 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 PJD2_k127_470323_1 1121090.KB894705_gene1059 2.489e-42 162.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,1ZC7I@1386|Bacillus 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro PJD2_k127_4710372_0 1499967.BAYZ01000063_gene6022 1.323e-109 377.0 COG1216@1|root,COG2148@1|root,COG1216@2|Bacteria,COG2148@2|Bacteria,2NP9Z@2323|unclassified Bacteria 2|Bacteria GM Glycosyltransferase like family 2 - - - ko:K03606,ko:K07011 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2 PJD2_k127_4710372_7 518766.Rmar_1399 2.995e-78 268.0 COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes 976|Bacteroidetes S Pfam Glycosyl transferase family 2 dpm1 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 PJD2_k127_4710372_4 290317.Cpha266_2437 3.427e-94 340.0 COG5617@1|root,COG5617@2|Bacteria,1FDV6@1090|Chlorobi 1090|Chlorobi S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - YfhO PJD2_k127_4710372_5 945713.IALB_2891 9.167e-93 319.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 arnC - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 PJD2_k127_4710372_2 525904.Tter_2834 3.133e-105 351.0 COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria 2|Bacteria M Polysaccharide biosynthesis protein ytcB - 5.1.3.2,5.1.3.6 ko:K01784,ko:K08679 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01385,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd PJD2_k127_4710372_1 1379698.RBG1_1C00001G0356 4.579e-107 377.0 COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria 2|Bacteria EG Protein of unknown function (DUF2723) - - - ko:K16928 - M00582 - - ko00000,ko00002,ko02000 3.A.1.33 - - DUF2723,QueT PJD2_k127_4710372_13 59374.Fisuc_0693 2.781e-35 147.0 COG0392@1|root,COG0392@2|Bacteria 2|Bacteria M lysyltransferase activity - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM PJD2_k127_4710372_3 1379698.RBG1_1C00001G1319 1.323e-97 331.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_4710372_9 59374.Fisuc_0695 1.403e-59 215.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 PJD2_k127_4710372_10 880073.Calab_0215 8.3e-53 196.0 COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria 2|Bacteria T Calcineurin-like phosphoesterase superfamily domain apaH - - - - - - - - - - - Metallophos_2 PJD2_k127_4710372_14 1121930.AQXG01000001_gene1410 5.717e-28 119.0 COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes 976|Bacteroidetes K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB PJD2_k127_4710372_12 66692.ABC1813 1.065e-39 152.0 COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,1ZFJ6@1386|Bacillus 91061|Bacilli H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08940 DMRL_synthase PJD2_k127_4710372_8 909663.KI867150_gene833 9.921e-73 248.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MQ94@213462|Syntrophobacterales 28221|Deltaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 PJD2_k127_4710372_6 925409.KI911562_gene1877 1.811e-86 295.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1INQM@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 PJD2_k127_4710372_11 521098.Aaci_0937 1.33e-45 171.0 COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,278YZ@186823|Alicyclobacillaceae 91061|Bacilli H Lumazine binding domain ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08950,iYO844.BSU23270 Lum_binding PJD2_k127_4710372_15 1161401.ASJA01000009_gene1771 2.176e-07 59.0 COG1985@1|root,COG1985@2|Bacteria,1N4VZ@1224|Proteobacteria,2TXAC@28211|Alphaproteobacteria,43XVI@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Riboflavin biosynthesis protein RibD - - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C PJD2_k127_4769354_0 1232410.KI421415_gene2974 8.742e-154 496.0 COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria,43UJW@69541|Desulfuromonadales 28221|Deltaproteobacteria S Glutamate-cysteine ligase family 2(GCS2) - - - - - - - - - - - - GCS2 PJD2_k127_4769354_1 292415.Tbd_1455 5.582e-66 234.0 COG3931@1|root,COG3931@2|Bacteria,1PWF0@1224|Proteobacteria,2VZYZ@28216|Betaproteobacteria,1KSK2@119069|Hydrogenophilales 119069|Hydrogenophilales E N-formylglutamate amidohydrolase - - - - - - - - - - - - FGase PJD2_k127_4769354_5 44060.JODL01000011_gene2011 7.319e-07 61.0 COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria 201174|Actinobacteria O Peptidase s1 and s6 chymotrypsin hap sprI - - ko:K08372 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Trypsin_2 PJD2_k127_4769354_6 1120936.KB907225_gene2660 0.0001546 53.0 COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4EFR5@85012|Streptosporangiales 201174|Actinobacteria T Lon protease (S16) C-terminal proteolytic domain lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 PJD2_k127_4769354_3 863365.XHC_1534 2.68e-31 129.0 COG1595@1|root,COG1595@2|Bacteria,1R7KF@1224|Proteobacteria,1S2IU@1236|Gammaproteobacteria,1XC71@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_4769354_4 1121920.AUAU01000017_gene1199 1.867e-25 113.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_C_4,TetR_N PJD2_k127_4769354_2 1232410.KI421421_gene3263 2.654e-40 154.0 COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,42NXK@68525|delta/epsilon subdivisions,2WMGN@28221|Deltaproteobacteria,43TBF@69541|Desulfuromonadales 28221|Deltaproteobacteria C Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - - - - - - - - - - Hemerythrin,ScdA_N PJD2_k127_4834849_5 1121930.AQXG01000023_gene1641 1.598e-05 58.0 COG3209@1|root,COG3209@2|Bacteria,4P5ZD@976|Bacteroidetes 976|Bacteroidetes M COG3209 Rhs family protein - - - - - - - - - - - - - PJD2_k127_4834849_1 945713.IALB_0461 1.324e-89 321.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family aprN - - - - - - - - - - - Peptidase_S8 PJD2_k127_4834849_0 316067.Geob_1578 0.0 1121.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43TQ2@69541|Desulfuromonadales 28221|Deltaproteobacteria H Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N PJD2_k127_4834849_4 1380370.JIBA01000014_gene1774 1.329e-06 60.0 COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4FGM3@85021|Intrasporangiaceae 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf PJD2_k127_4834849_6 517418.Ctha_0506 0.0001788 53.0 COG1555@1|root,COG1555@2|Bacteria,1FE73@1090|Chlorobi 1090|Chlorobi L photosystem II stabilization - - - - - - - - - - - - HHH_3 PJD2_k127_4834849_2 771875.Ferpe_1782 5.152e-16 85.0 COG0296@1|root,COG4945@1|root,COG0296@2|Bacteria,COG4945@2|Bacteria,2GC51@200918|Thermotogae 200918|Thermotogae G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - AMPK1_CBM,Glucodextran_C,Glyco_hydro_57 PJD2_k127_4841841_6 880073.Calab_2857 1.9e-19 93.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - DUF2808,Peptidase_S46 PJD2_k127_4841841_2 1304885.AUEY01000003_gene491 1.956e-46 173.0 COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,2MK9C@213118|Desulfobacterales 28221|Deltaproteobacteria P Iron-storage protein ftn - 1.16.3.2 ko:K02217 - - - - ko00000,ko01000 - - - Ferritin PJD2_k127_4841841_0 1191523.MROS_1530 1.574e-219 711.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,PD40,Peptidase_S9 PJD2_k127_4841841_5 1283300.ATXB01000002_gene3020 9.164e-22 111.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XEH5@135618|Methylococcales 135618|Methylococcales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N PJD2_k127_4841841_4 1227454.C446_13059 4.806e-31 141.0 COG3379@1|root,arCOG01377@2157|Archaea,2XUWW@28890|Euryarchaeota,23RZ5@183963|Halobacteria 183963|Halobacteria S type I phosphodiesterase nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_4841841_8 196162.Noca_1204 9.433e-11 74.0 COG2866@1|root,COG2866@2|Bacteria,2HYFV@201174|Actinobacteria,4DUIW@85009|Propionibacteriales 201174|Actinobacteria E Protein of unknown function (DUF2817) - - - - - - - - - - - - Peptidase_M14 PJD2_k127_4841841_3 234267.Acid_6834 6.948e-33 137.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria 2|Bacteria KU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 PJD2_k127_4841841_9 251221.35211910 4.809e-05 54.0 COG0515@1|root,COG0515@2|Bacteria,1G0FM@1117|Cyanobacteria 1117|Cyanobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase PJD2_k127_4841841_1 1232410.KI421416_gene2655 5.157e-64 227.0 28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria,43U05@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_4841841_7 319225.Plut_1741 6.018e-16 87.0 COG1595@1|root,COG1595@2|Bacteria,1FE7H@1090|Chlorobi 1090|Chlorobi K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_4854928_7 204669.Acid345_4057 4.069e-38 154.0 COG0791@1|root,COG0791@2|Bacteria,3Y5IG@57723|Acidobacteria 57723|Acidobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60,SPOR PJD2_k127_4854928_3 379066.GAU_0641 8.887e-81 282.0 COG1173@1|root,COG1173@2|Bacteria,1ZT0U@142182|Gemmatimonadetes 142182|Gemmatimonadetes EP N-terminal TM domain of oligopeptide transport permease C - - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N PJD2_k127_4854928_1 1379270.AUXF01000004_gene3278 6.093e-95 327.0 COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes 142182|Gemmatimonadetes U Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 PJD2_k127_4854928_0 379066.GAU_0607 2.533e-110 376.0 COG4166@1|root,COG4166@2|Bacteria,1ZSMX@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 PJD2_k127_4854928_8 1519464.HY22_11300 6.566e-33 144.0 COG4219@1|root,COG4219@2|Bacteria,1FF12@1090|Chlorobi 1090|Chlorobi KT Peptidase M56 - - - - - - - - - - - - - PJD2_k127_4854928_6 1047013.AQSP01000140_gene2536 2.56e-74 266.0 COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria 2|Bacteria V COGs COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD PJD2_k127_4854928_5 240015.ACP_2007 6.298e-78 276.0 COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JI8C@204432|Acidobacteriia 204432|Acidobacteriia V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD PJD2_k127_4854928_4 1379698.RBG1_1C00001G1364 9.59e-80 281.0 COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family macA - - ko:K02005,ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP PJD2_k127_4854928_2 517418.Ctha_0586 9.628e-90 304.0 COG1136@1|root,COG1136@2|Bacteria,1FDKJ@1090|Chlorobi 1090|Chlorobi P PFAM ABC transporter related - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran PJD2_k127_4854928_9 880073.Calab_1158 1.827e-29 133.0 COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria 2|Bacteria MU Outer membrane efflux protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP PJD2_k127_4880353_12 555079.Toce_0739 3.119e-56 200.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,42EWM@68295|Thermoanaerobacterales 186801|Clostridia L Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC PJD2_k127_4880353_3 1379698.RBG1_1C00001G1860 1.431e-144 465.0 COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria 2|Bacteria D MreB/Mbl protein mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl PJD2_k127_4880353_16 59374.Fisuc_1901 2.619e-29 128.0 COG1792@1|root,COG1792@2|Bacteria 2|Bacteria M regulation of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC PJD2_k127_4880353_20 926692.AZYG01000004_gene2097 1.621e-11 74.0 COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24RP5@186801|Clostridia,3WAXZ@53433|Halanaerobiales 186801|Clostridia M TIGRFAM rod shape-determining protein MreD mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD PJD2_k127_4880353_6 1379698.RBG1_1C00001G1003 9.832e-109 375.0 COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria 2|Bacteria M Penicillin-binding protein 2 mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase PJD2_k127_4880353_7 1379698.RBG1_1C00001G1004 1.541e-86 304.0 COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria 2|Bacteria D Peptidoglycan polymerase that is essential for cell wall elongation rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE PJD2_k127_4880353_13 1379698.RBG1_1C00001G1006 4.899e-53 198.0 COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria 2|Bacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT PJD2_k127_4880353_19 1304275.C41B8_00680 7.508e-12 75.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Competence protein gntX GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - Pribosyltran PJD2_k127_4880353_4 880073.Calab_3781 3.367e-138 446.0 COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria 2|Bacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N PJD2_k127_4880353_2 945713.IALB_1271 8.237e-146 472.0 COG0126@1|root,COG0126@2|Bacteria 2|Bacteria F phosphoglycerate kinase activity pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK PJD2_k127_4880353_9 370438.PTH_2721 2.184e-79 272.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae 186801|Clostridia G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM PJD2_k127_4880353_17 1379698.RBG1_1C00001G1012 3.491e-14 77.0 COG1314@1|root,COG1314@2|Bacteria,2NQ7S@2323|unclassified Bacteria 2|Bacteria U Preprotein translocase SecG subunit secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG PJD2_k127_4880353_5 243231.GSU3318 9.089e-135 445.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales 28221|Deltaproteobacteria S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139,DUF4140 PJD2_k127_4880353_18 411463.EUBVEN_01617 1.988e-12 74.0 COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,25WKE@186806|Eubacteriaceae 186801|Clostridia D Protein of unknown function (DUF4446) - - - - - - - - - - - - DUF4446 PJD2_k127_4880353_10 649638.Trad_1635 7.035e-65 239.0 COG0534@1|root,COG0534@2|Bacteria,1WKWJ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V COGs COG0534 Na -driven multidrug efflux pump - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE PJD2_k127_4880353_11 1379698.RBG1_1C00001G1850 1.459e-58 213.0 COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria 2|Bacteria S Rhomboid family - - - - - - - - - - - - Rhomboid PJD2_k127_4880353_14 1121104.AQXH01000001_gene1411 2.104e-52 201.0 COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 PJD2_k127_4880353_0 1121930.AQXG01000001_gene1203 8.288e-291 926.0 COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran PJD2_k127_4880353_1 1121104.AQXH01000001_gene1413 1.074e-192 638.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran PJD2_k127_4880353_15 944481.JAFP01000001_gene1050 1.895e-41 155.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2M7A3@213113|Desulfurellales 28221|Deltaproteobacteria O Thioredoxin trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin PJD2_k127_4880353_8 1123288.SOV_4c04230 1.501e-84 301.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes 909932|Negativicutes E ABC transporter substrate-binding protein - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 PJD2_k127_4920759_6 1382306.JNIM01000001_gene844 1.249e-13 81.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT_2 PJD2_k127_4920759_4 573061.Clocel_2117 8.458e-16 90.0 COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia,36ERI@31979|Clostridiaceae 186801|Clostridia M O-Antigen ligase - - - ko:K18814 - - - - ko00000,ko02000 9.B.67.1 - - Wzy_C PJD2_k127_4920759_7 7029.ACYPI088919-PA 2.675e-05 57.0 2D8GD@1|root,2TA48@2759|Eukaryota,3AJS4@33154|Opisthokonta,3BZQQ@33208|Metazoa,3DGE8@33213|Bilateria,429IP@6656|Arthropoda,3SRMT@50557|Insecta 33208|Metazoa S Bacterial Ig-like domain (group 3) - - - - - - - - - - - - Big_3_2 PJD2_k127_4920759_0 1128421.JAGA01000003_gene3146 3.17e-72 253.0 COG0846@1|root,COG0846@2|Bacteria,2NPJR@2323|unclassified Bacteria 2|Bacteria K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 PJD2_k127_4920759_2 1191523.MROS_0145 1.916e-43 170.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination pagO - - ko:K07790 ko02020,map02020 - - - ko00000,ko00001 2.A.7 - - EamA PJD2_k127_4920759_3 290400.Jann_4252 4.465e-27 127.0 COG1287@1|root,COG1287@2|Bacteria 2|Bacteria S oligosaccharyl transferase activity - - - - - - - - - - - - PMT_2 PJD2_k127_4920759_1 880073.Calab_0150 1.998e-53 200.0 COG1597@1|root,COG1597@2|Bacteria,2NQYH@2323|unclassified Bacteria 2|Bacteria I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat PJD2_k127_4920759_5 1121104.AQXH01000001_gene1459 1.813e-14 87.0 COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1IQDC@117747|Sphingobacteriia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3,Reg_prop,Y_Y_Y PJD2_k127_4920792_0 880073.Calab_1878 2.131e-166 534.0 2CD20@1|root,2Z7SQ@2|Bacteria,2NNUF@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_4920792_5 471870.BACINT_01621 4.224e-06 60.0 COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia,4AM5H@815|Bacteroidaceae 976|Bacteroidetes S Tetratricopeptide repeat protein - - - - - - - - - - - - TPR_16,TPR_2,TPR_21,TPR_6,TPR_8 PJD2_k127_4920792_1 945713.IALB_0415 6.683e-89 330.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - - PJD2_k127_4920792_3 861299.J421_2976 1.391e-65 235.0 COG1657@1|root,COG1657@2|Bacteria,1ZSPV@142182|Gemmatimonadetes 142182|Gemmatimonadetes I Domain of unknown function (DUF4159) - - - - - - - - - - - - DUF4159 PJD2_k127_4920792_4 1499967.BAYZ01000136_gene44 1.029e-48 180.0 COG1499@1|root,COG1499@2|Bacteria,2NS26@2323|unclassified Bacteria 2|Bacteria J ribosomal large subunit export from nucleus - - - - - - - - - - - - NMD3 PJD2_k127_4920792_2 929556.Solca_3116 3.088e-82 289.0 COG1835@1|root,COG1835@2|Bacteria,4NMNZ@976|Bacteroidetes,1IQXU@117747|Sphingobacteriia 976|Bacteroidetes I Domain of unknown function (DUF4153) - - - - - - - - - - - - DUF4153 PJD2_k127_4963103_16 1379698.RBG1_1C00001G0297 2.618e-20 91.0 COG4881@1|root,COG4881@2|Bacteria 2|Bacteria - - cbcU - - - - - - - - - - - NrfD PJD2_k127_4963103_2 1379698.RBG1_1C00001G0296 2.585e-98 327.0 COG0437@1|root,COG0437@2|Bacteria,2NR78@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S binding domain ttrB - - ko:K08358 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3.10 - - Fer4_11,Fer4_3,Fer4_7 PJD2_k127_4963103_5 1379698.RBG1_1C00001G0295 1.01e-77 268.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - ko:K04013,ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 - - - Cytochrom_C552,Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1 PJD2_k127_4963103_10 1384049.CD29_11055 2.329e-44 173.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,3IW4Y@400634|Lysinibacillus 91061|Bacilli F phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK PJD2_k127_4963103_6 1123242.JH636434_gene4627 7.532e-75 271.0 COG2107@1|root,COG2107@2|Bacteria,2IXIY@203682|Planctomycetes 203682|Planctomycetes S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnD - - ko:K11785 ko00130,ko01110,map00130,map01110 - R08589 RC02330 ko00000,ko00001,ko01000 - - - VitK2_biosynth PJD2_k127_4963103_14 880073.Calab_0921 9.763e-22 112.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 PJD2_k127_4963103_15 459349.CLOAM1790 8.452e-21 109.0 COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria 2|Bacteria K Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS PJD2_k127_4963103_21 1128421.JAGA01000002_gene1356 3.623e-05 56.0 COG1807@1|root,COG1807@2|Bacteria 1128421.JAGA01000002_gene1356|- M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - - PJD2_k127_4963103_7 1237149.C900_05249 2.899e-70 245.0 COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,OmpA,PD40 PJD2_k127_4963103_11 1254432.SCE1572_31450 7.24e-40 157.0 COG0800@1|root,COG0800@2|Bacteria,1RD0T@1224|Proteobacteria,43B68@68525|delta/epsilon subdivisions 1224|Proteobacteria G KDPG and KHG aldolase dgoA GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008674,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034192,GO:0034194,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.1.2.14,4.1.2.21,4.1.3.42 ko:K01625,ko:K01631 ko00030,ko00052,ko00630,ko01100,ko01120,ko01200,map00030,map00052,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00552,M00631 R00470,R01064,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase PJD2_k127_4963103_18 1191523.MROS_0656 1.151e-10 74.0 28P4Q@1|root,2ZBZV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_4963103_20 595460.RRSWK_03208 4.509e-07 57.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - CBM_6,PSCyt1,PSCyt2,PSD1 PJD2_k127_4963103_8 1123277.KB893173_gene1808 8.154e-47 172.0 COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,47QIW@768503|Cytophagia 976|Bacteroidetes E Glyoxalase-like domain - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase PJD2_k127_4963103_0 357808.RoseRS_1218 3.049e-169 539.0 COG1899@1|root,COG1899@2|Bacteria,2G7R7@200795|Chloroflexi,374VZ@32061|Chloroflexia 32061|Chloroflexia O PFAM deoxyhypusine synthase - - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS PJD2_k127_4963103_12 357808.RoseRS_4462 1.592e-39 158.0 294HY@1|root,2ZRXK@2|Bacteria,2GAIJ@200795|Chloroflexi,376D9@32061|Chloroflexia 32061|Chloroflexia S YwiC-like protein - - - - - - - - - - - - YwiC PJD2_k127_4963103_4 1254432.SCE1572_39205 8.873e-81 277.0 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2WUIA@28221|Deltaproteobacteria,2YV7F@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the MtfA family - - - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 PJD2_k127_4963103_13 331678.Cphamn1_1310 2.52e-29 122.0 COG0388@1|root,COG0388@2|Bacteria 2|Bacteria S hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - 3.5.5.1 ko:K01501 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase PJD2_k127_4963103_19 1499680.CCFE01000033_gene3947 1.557e-09 60.0 COG4877@1|root,COG4877@2|Bacteria,1VEY1@1239|Firmicutes,4HNMN@91061|Bacilli,1ZJ24@1386|Bacillus 91061|Bacilli S protein conserved in bacteria - - - - - - - - - - - - Arc,HicB,RHH_5 PJD2_k127_4963103_3 382464.ABSI01000010_gene3212 1.234e-91 310.0 COG0330@1|root,COG0330@2|Bacteria,46USS@74201|Verrucomicrobia,2IVC2@203494|Verrucomicrobiae 203494|Verrucomicrobiae O prohibitin homologues - - - - - - - - - - - - Band_7 PJD2_k127_4963103_1 204669.Acid345_0604 2.581e-125 433.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia 204432|Acidobacteriia KLT Protein kinase domain - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_11,TPR_16,TPR_2,TPR_8 PJD2_k127_4963103_9 1353528.DT23_00925 8.694e-46 190.0 COG2304@1|root,COG2304@2|Bacteria,1R7H7@1224|Proteobacteria 1224|Proteobacteria O von Willebrand factor type A domain - - - - - - - - - - - - Peptidase_M64,VWA,VWA_2 PJD2_k127_4963103_17 1122138.AQUZ01000032_gene7172 1.419e-18 101.0 COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,2GIRE@201174|Actinobacteria,4DSF1@85009|Propionibacteriales 201174|Actinobacteria O Subtilase family mycP - - ko:K14743 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 PJD2_k127_4963927_0 1122176.KB903532_gene2470 0.0 1034.0 COG3459@1|root,COG3459@2|Bacteria,4PM7T@976|Bacteroidetes,1IVNA@117747|Sphingobacteriia 976|Bacteroidetes G Glycosyltransferase 36 associated - - - - - - - - - - - - - PJD2_k127_4963927_1 1379270.AUXF01000003_gene3412 2.035e-216 681.0 COG2211@1|root,COG2211@2|Bacteria,1ZV78@142182|Gemmatimonadetes 142182|Gemmatimonadetes G MFS/sugar transport protein - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 PJD2_k127_4963927_2 518766.Rmar_0086 1.581e-149 479.0 COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1FJJ9@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red PJD2_k127_4979485_0 1379698.RBG1_1C00001G1445 1.37e-113 391.0 COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria 2|Bacteria MU WD40-like Beta Propeller Repeat - - - ko:K03641,ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33,2.C.1.2 - - BSP,Bac_surface_Ag,PD40,Peptidase_MA_2 PJD2_k127_4979485_1 1396418.BATQ01000135_gene3640 1.979e-58 218.0 COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,2ITVJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase PJD2_k127_4979485_3 518766.Rmar_0462 2.701e-18 97.0 COG2372@1|root,COG2372@2|Bacteria,4PM5M@976|Bacteroidetes,1FIJV@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Bacterial Ig-like domain - - - - - - - - - - - - Big_5,CarboxypepD_reg PJD2_k127_4979485_2 56780.SYN_02156 9.704e-46 169.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2MQ5Z@213462|Syntrophobacterales 28221|Deltaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 ko:K00611,ko:K09065 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N PJD2_k127_500714_1 880073.Calab_1105 9.082e-59 231.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - ko:K17713,ko:K20952 ko05111,map05111 - - - ko00000,ko00001,ko02000 1.B.33.1 - - Beta-prism_lec,PQQ_2,PQQ_3,Peptidase_S8,Pkinase,VCBS PJD2_k127_500714_0 439235.Dalk_3434 2.082e-299 942.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales 28221|Deltaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N PJD2_k127_500714_5 1297742.A176_05385 7.334e-07 62.0 COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,438GF@68525|delta/epsilon subdivisions,2X3RA@28221|Deltaproteobacteria,2YWWZ@29|Myxococcales 28221|Deltaproteobacteria M Bacterial Ig-like domain (group 1) - - - - - - - - - - - - Big_1,LTD PJD2_k127_500714_2 592031.GCWU000322_00643 1.022e-53 203.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,25URC@186806|Eubacteriaceae 186801|Clostridia D CobQ CobB MinD ParA nucleotide binding domain soj - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 PJD2_k127_500714_4 1165094.RINTHH_5180 5.161e-27 116.0 COG1963@1|root,COG1963@2|Bacteria,1G5PI@1117|Cyanobacteria,1HN85@1161|Nostocales 1117|Cyanobacteria S PFAM Divergent PAP2 family - - - ko:K09775 - - - - ko00000 - - - DUF212 PJD2_k127_500714_3 795797.C497_13096 2.367e-30 131.0 COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,23STJ@183963|Halobacteria 183963|Halobacteria I COG0183 Acetyl-CoA acetyltransferase acaB1 - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N PJD2_k127_5022718_22 1379698.RBG1_1C00001G0682 6.082e-06 55.0 COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - ko:K20306 - - - - ko00000,ko04131 - - - Lipase_GDSL,Lipase_GDSL_2 PJD2_k127_5022718_5 667014.Thein_0626 8.211e-126 436.0 COG0612@1|root,COG0612@2|Bacteria,2GH66@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Belongs to the peptidase M16 family - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_5022718_9 880073.Calab_1372 2.81e-72 252.0 COG1624@1|root,COG1624@2|Bacteria,2NPQS@2323|unclassified Bacteria 2|Bacteria S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N,YojJ PJD2_k127_5022718_8 349124.Hhal_1769 4.134e-77 268.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1WXND@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind PJD2_k127_5022718_0 1379698.RBG1_1C00001G1627 6.415e-232 736.0 COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria 2|Bacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 PJD2_k127_5022718_16 1203602.HMPREF1527_00957 1.18e-48 184.0 COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CVQW@84998|Coriobacteriia 84998|Coriobacteriia F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran PJD2_k127_5022718_13 671143.DAMO_1566 1.922e-53 207.0 COG0037@1|root,COG0037@2|Bacteria,2NPAZ@2323|unclassified Bacteria 2|Bacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,Pribosyltran,TilS,TilS_C PJD2_k127_5022718_6 161156.JQKW01000007_gene861 2.721e-105 354.0 COG0059@1|root,COG0059@2|Bacteria,2GH4M@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN PJD2_k127_5022718_7 378806.STAUR_1355 3.124e-102 346.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1RAQ0@1224|Proteobacteria,42PCB@68525|delta/epsilon subdivisions,2X357@28221|Deltaproteobacteria,2YUBM@29|Myxococcales 28221|Deltaproteobacteria S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE PJD2_k127_5022718_17 502025.Hoch_6556 2.12e-46 172.0 COG1522@1|root,COG1522@2|Bacteria,1RJK0@1224|Proteobacteria,43B4T@68525|delta/epsilon subdivisions,2X6IH@28221|Deltaproteobacteria,2Z3B8@29|Myxococcales 28221|Deltaproteobacteria K helix_turn_helix ASNC type - - - - - - - - - - - - AsnC_trans_reg PJD2_k127_5022718_18 638303.Thal_1575 5.017e-36 145.0 COG1999@1|root,COG1999@2|Bacteria 2|Bacteria M signal sequence binding - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC PJD2_k127_5022718_19 234267.Acid_3899 5.383e-36 141.0 COG1959@1|root,COG1959@2|Bacteria,3Y8ZE@57723|Acidobacteria 57723|Acidobacteria K Transcriptional regulator - - - - - - - - - - - - Rrf2 PJD2_k127_5022718_10 391615.ABSJ01000032_gene712 7.281e-71 250.0 COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H protein methyltransferase activity - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 PJD2_k127_5022718_2 1121930.AQXG01000002_gene2379 6.517e-161 521.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1IUW3@117747|Sphingobacteriia 976|Bacteroidetes P Rhodanese Homology Domain - - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B,Rhodanese PJD2_k127_5022718_4 502025.Hoch_4149 2.306e-135 446.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria,2YYFS@29|Myxococcales 28221|Deltaproteobacteria E alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp PJD2_k127_5022718_20 1108045.GORHZ_245_00090 1.44e-33 143.0 COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria,4GABU@85026|Gordoniaceae 201174|Actinobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C PJD2_k127_5022718_23 1125725.HMPREF1325_1926 0.0006336 52.0 COG0457@1|root,COG0457@2|Bacteria,2J5SR@203691|Spirochaetes 203691|Spirochaetes S domain protein - - - - - - - - - - - - ANAPC3,TPR_16,TPR_19,TPR_6,TPR_8 PJD2_k127_5022718_1 880073.Calab_1667 2.821e-161 534.0 COG1757@1|root,COG1757@2|Bacteria,2NPD8@2323|unclassified Bacteria 2|Bacteria C Na+/H+ antiporter family nhaC - - - - - - - - - - - Na_H_antiporter PJD2_k127_5022718_3 448385.sce6195 1.643e-155 503.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YX7D@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N PJD2_k127_5022718_21 436229.JOEH01000039_gene2032 6.085e-07 55.0 2AZ6G@1|root,31RD9@2|Bacteria,2HTHN@201174|Actinobacteria,2NMV4@228398|Streptacidiphilus 201174|Actinobacteria - - - - - - - - - - - - - - - PJD2_k127_5022718_12 1379698.RBG1_1C00001G0710 3.525e-66 233.0 COG1945@1|root,COG1945@2|Bacteria,2NP74@2323|unclassified Bacteria 2|Bacteria S Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) pdaD - 4.1.1.19 ko:K02626 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PvlArgDC PJD2_k127_5022718_14 1379698.RBG1_1C00001G0708 2.416e-53 198.0 COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria 2|Bacteria E Arginase family speB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase PJD2_k127_5022718_11 1167006.UWK_02488 1.891e-68 249.0 COG2271@1|root,COG2271@2|Bacteria,1NJTU@1224|Proteobacteria 1224|Proteobacteria G Major facilitator Superfamily MA20_01130 - - - - - - - - - - - MFS_1 PJD2_k127_5022718_15 357808.RoseRS_3748 2.544e-49 187.0 COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia 32061|Chloroflexia O PFAM magnesium chelatase ChlI subunit - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C PJD2_k127_5035329_7 326427.Cagg_1684 6.241e-65 233.0 COG1668@1|root,COG1668@2|Bacteria,2G9RA@200795|Chloroflexi 200795|Chloroflexi CP ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 PJD2_k127_5035329_4 1382356.JQMP01000003_gene1468 6.932e-105 352.0 COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi,27Z66@189775|Thermomicrobia 189775|Thermomicrobia V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran PJD2_k127_5035329_5 1121920.AUAU01000012_gene2645 5.875e-98 330.0 COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria 57723|Acidobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - - - - - - - - - - Radical_SAM PJD2_k127_5035329_8 525904.Tter_0097 2.316e-61 219.0 COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria 2|Bacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 ko:K03644,ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07767,R07768,R07769 RC00039,RC00992,RC01978,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB PJD2_k127_5035329_3 1121920.AUAU01000004_gene789 1.518e-110 372.0 COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria 57723|Acidobacteria C e3 binding domain - - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding PJD2_k127_5035329_0 234267.Acid_0353 2.417e-146 469.0 COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria 57723|Acidobacteria C Transketolase, pyrimidine binding domain - - 1.2.4.4 ko:K00167 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C PJD2_k127_5035329_2 234267.Acid_0352 1.668e-122 402.0 COG1071@1|root,COG1071@2|Bacteria,3Y4M3@57723|Acidobacteria 57723|Acidobacteria C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh PJD2_k127_5035329_6 861299.J421_3598 2.677e-92 314.0 COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes 2|Bacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) bfmBA - 1.2.4.1,1.2.4.4 ko:K00161,ko:K11381,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C PJD2_k127_5035329_1 234267.Acid_0912 9.594e-139 457.0 COG1249@1|root,COG1249@2|Bacteria,3Y2M8@57723|Acidobacteria 57723|Acidobacteria C Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim PJD2_k127_5035329_9 497964.CfE428DRAFT_3992 2.661e-23 106.0 COG1832@1|root,COG1832@2|Bacteria 2|Bacteria S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 PJD2_k127_5035329_10 926560.KE387023_gene1132 1.375e-16 89.0 COG3584@1|root,COG3584@2|Bacteria,1WKHT@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S 3D domain protein - - - - - - - - - - - - - PJD2_k127_5040157_4 530564.Psta_2811 2.529e-45 170.0 COG0113@1|root,COG0113@2|Bacteria,2IWU8@203682|Planctomycetes 203682|Planctomycetes H Belongs to the ALAD family - - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD PJD2_k127_5040157_7 338966.Ppro_3374 1.017e-34 144.0 COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,43U2R@69541|Desulfuromonadales 28221|Deltaproteobacteria H Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase hemD - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 ko:K02302,ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947 RC00003,RC00871,RC01012,RC01034,RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4,TP_methylase PJD2_k127_5040157_3 338963.Pcar_3063 3.552e-78 274.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,43T66@69541|Desulfuromonadales 28221|Deltaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC PJD2_k127_5040157_1 243231.GSU3284 9.869e-97 331.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH PJD2_k127_5040157_5 404380.Gbem_0406 1.825e-40 160.0 COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43TXA@69541|Desulfuromonadales 28221|Deltaproteobacteria O PFAM cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm PJD2_k127_5040157_8 926550.CLDAP_18620 2.944e-11 69.0 COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi 200795|Chloroflexi S Uncharacterized conserved protein (DUF2203) - - - - - - - - - - - - DUF2203 PJD2_k127_5040157_0 1184267.A11Q_779 5.805e-182 587.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,42PTE@68525|delta/epsilon subdivisions,2MTRM@213481|Bdellovibrionales,2WKRZ@28221|Deltaproteobacteria 213481|Bdellovibrionales C Electron transfer flavoprotein-ubiquinone - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO PJD2_k127_5040157_6 502025.Hoch_4515 3.29e-39 153.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2WRSP@28221|Deltaproteobacteria,2Z31G@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_7 PJD2_k127_5040157_2 1379698.RBG1_1C00001G0684 6.589e-94 315.0 COG0277@1|root,COG0277@2|Bacteria,2NP1E@2323|unclassified Bacteria 2|Bacteria C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104,ko:K18930 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 PJD2_k127_50444_4 1118060.CAGZ01000023_gene757 1.789e-23 101.0 COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CUEV@84998|Coriobacteriia 84998|Coriobacteriia J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 PJD2_k127_50444_1 635013.TherJR_2166 2.843e-103 362.0 COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,260BS@186807|Peptococcaceae 186801|Clostridia M TIGRFAM stage V sporulation protein D spoVD - - ko:K08384 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PASTA,PBP_dimer,Transpeptidase PJD2_k127_50444_2 867903.ThesuDRAFT_01664 2.265e-99 351.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WCXE@538999|Clostridiales incertae sedis 186801|Clostridia M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M PJD2_k127_50444_3 1121468.AUBR01000006_gene360 8.78e-68 249.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,42EWR@68295|Thermoanaerobacterales 186801|Clostridia M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M PJD2_k127_50444_0 1379698.RBG1_1C00001G0393 1.369e-142 464.0 COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria 2|Bacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105 Glycos_transf_4,MraY_sig1 PJD2_k127_50444_5 203120.LEUM_1496 8.354e-05 49.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,4AWNC@81850|Leuconostocaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M PJD2_k127_5047818_0 1047013.AQSP01000139_gene2352 9.483e-152 492.0 COG2866@1|root,COG2866@2|Bacteria 2|Bacteria E metallocarboxypeptidase activity - - - ko:K14054 - - - - ko00000 - - - AstE_AspA,Peptidase_M14 PJD2_k127_5060655_3 632335.Calkr_0842 8.594e-19 88.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42FPS@68295|Thermoanaerobacterales 186801|Clostridia J TIGRFAM Translation elongation factor fusA2 - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 PJD2_k127_5060655_6 278963.ATWD01000001_gene2549 1.904e-05 57.0 2BRBT@1|root,32KAC@2|Bacteria,3Y4U0@57723|Acidobacteria,2JJJP@204432|Acidobacteriia 204432|Acidobacteriia S Yip1 domain - - - - - - - - - - - - Yip1 PJD2_k127_5060655_0 290318.Cvib_0237 2e-49 191.0 COG0438@1|root,COG0438@2|Bacteria,1FE7C@1090|Chlorobi 1090|Chlorobi M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4 PJD2_k127_5060655_1 1247963.JPHU01000002_gene2461 1.107e-31 144.0 COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,2U3JJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_5060655_2 1042209.HK44_010340 2.223e-22 109.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1YNY6@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria O Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 PJD2_k127_5060655_5 1163408.UU9_04192 5.382e-10 72.0 COG3307@1|root,COG3307@2|Bacteria,1N4HJ@1224|Proteobacteria,1SWM6@1236|Gammaproteobacteria,1X57W@135614|Xanthomonadales 135614|Xanthomonadales M O-Antigen ligase - - - - - - - - - - - - Wzy_C PJD2_k127_5060655_4 330214.NIDE0890 3.307e-15 83.0 COG3206@1|root,COG3206@2|Bacteria 2|Bacteria M extracellular polysaccharide biosynthetic process - - 3.1.21.3 ko:K01153,ko:K05789,ko:K07011,ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01005,ko02000,ko02048 8.A.3.1 - - GNVR,Wzz PJD2_k127_5074126_5 1379698.RBG1_1C00001G1773 9.01e-54 203.0 COG0457@1|root,COG0457@2|Bacteria,2NP5J@2323|unclassified Bacteria 2|Bacteria S Oxygen tolerance - - - - - - - - - - - - BatD PJD2_k127_5074126_3 1379698.RBG1_1C00001G1774 9.813e-92 331.0 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria 2|Bacteria S von Willebrand factor (vWF) type A domain batB - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 PJD2_k127_5074126_2 880073.Calab_2474 8.291e-94 317.0 COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria 2|Bacteria NU von Willebrand factor (vWF) type A domain batA - - ko:K07114,ko:K12511 - - - - ko00000,ko02000,ko02044 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA PJD2_k127_5074126_7 575590.HMPREF0156_00728 2.036e-17 94.0 COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes 976|Bacteroidetes O Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - PJD2_k127_5074126_1 1379698.RBG1_1C00001G1778 9.479e-98 328.0 COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - - - - - - - - - - DUF58 PJD2_k127_5074126_0 1379698.RBG1_1C00001G1779 1.534e-132 438.0 COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria 2|Bacteria S ATPase associated with various cellular moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 PJD2_k127_5074126_4 1123371.ATXH01000045_gene1871 2.393e-66 238.0 28I4Y@1|root,2Z88D@2|Bacteria,2GI90@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria - - - - - - - - - - - - - - - PJD2_k127_5074126_6 1131269.AQVV01000016_gene1838 5.094e-51 192.0 COG0637@1|root,COG0637@2|Bacteria 2|Bacteria S phosphonoacetaldehyde hydrolase activity pgp - - - - - - - - - - - HAD_2 PJD2_k127_5074126_8 1463845.JOIG01000010_gene2126 3.766e-06 56.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria 201174|Actinobacteria L Belongs to the helicase family. UvrD subfamily uvrD3 - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C PJD2_k127_5099804_4 459349.CLOAM0866 4.346e-60 226.0 28JNG@1|root,2Z9ES@2|Bacteria,2NPDF@2323|unclassified Bacteria 2|Bacteria - - pgsW - - - - - - - - - - - - PJD2_k127_5099804_5 459349.CLOAM0865 2.948e-32 131.0 29EG8@1|root,334DW@2|Bacteria,2NPTE@2323|unclassified Bacteria 2|Bacteria S Capsule biosynthesis CapC capC - - ko:K22116 - - - - ko00000 - - - Caps_synth_CapC PJD2_k127_5099804_3 595460.RRSWK_06742 1.49e-86 304.0 COG0769@1|root,COG0769@2|Bacteria 2|Bacteria M UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity murE - 6.3.2.13 ko:K01928,ko:K01932 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M PJD2_k127_5099804_1 247490.KSU1_C0659 4.394e-99 357.0 COG0612@1|root,COG0612@2|Bacteria,2IWSI@203682|Planctomycetes 203682|Planctomycetes S Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_5099804_2 1125863.JAFN01000001_gene1391 1.181e-89 310.0 COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1PEPK@1224|Proteobacteria,42NJ8@68525|delta/epsilon subdivisions,2WM57@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM peptidase M1, membrane alanine aminopeptidase - - - - - - - - - - - iAF987.Gmet_0348 Peptidase_M1 PJD2_k127_5099804_0 472759.Nhal_2872 1.36e-133 452.0 COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1SYTD@1236|Gammaproteobacteria,1X2IM@135613|Chromatiales 135613|Chromatiales EO Peptidase family M28 - - - - - - - - - - - - PDZ_2,Peptidase_M1,Peptidase_M28 PJD2_k127_5100537_9 754477.Q7C_679 1.196e-24 108.0 COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,46112@72273|Thiotrichales 72273|Thiotrichales H queuosine biosynthesis protein QueD - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS PJD2_k127_5100537_2 1094980.Mpsy_2617 1.499e-52 193.0 COG0603@1|root,arCOG00039@2157|Archaea,2XTS7@28890|Euryarchaeota,2N9IW@224756|Methanomicrobia 224756|Methanomicrobia H Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC PJD2_k127_5100537_6 429009.Adeg_0592 1.015e-30 128.0 COG2029@1|root,COG2029@2|Bacteria,1V5P0@1239|Firmicutes,24IRW@186801|Clostridia,42GR7@68295|Thermoanaerobacterales 186801|Clostridia S Domain of unknown function (DUF366) - - - ko:K09139 - - - - ko00000 - - - DUF366 PJD2_k127_5100537_3 1121468.AUBR01000032_gene1171 1.912e-42 169.0 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,2499R@186801|Clostridia,42H0P@68295|Thermoanaerobacterales 186801|Clostridia H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM PJD2_k127_5100537_4 265072.Mfla_1875 2.28e-41 168.0 COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,2KKUP@206350|Nitrosomonadales 206350|Nitrosomonadales S Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 PJD2_k127_5100537_10 1121377.KB906398_gene2077 1.048e-05 57.0 COG3055@1|root,COG3291@1|root,COG4733@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - He_PIG,Laminin_G_3,Malectin,NPCBM,fn3 PJD2_k127_5100537_7 1379698.RBG1_1C00001G1143 3.731e-30 124.0 COG0776@1|root,COG0776@2|Bacteria,2NPU6@2323|unclassified Bacteria 2|Bacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup_1 - - ko:K03530,ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding PJD2_k127_5100537_0 1144275.COCOR_01334 2.294e-99 338.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales 28221|Deltaproteobacteria E Threonine aldolase ltaA - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase PJD2_k127_5100537_1 1034807.FBFL15_3002 1.579e-64 233.0 COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1HX5Y@117743|Flavobacteriia,2NSC7@237|Flavobacterium 976|Bacteroidetes H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase PJD2_k127_5100537_5 485913.Krac_8939 1.647e-34 139.0 COG0558@1|root,COG0558@2|Bacteria,2G6RT@200795|Chloroflexi 200795|Chloroflexi I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf PJD2_k127_5100537_8 665571.STHERM_c11260 5.187e-29 126.0 COG0125@1|root,COG0125@2|Bacteria,2J765@203691|Spirochaetes 203691|Spirochaetes F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin PJD2_k127_5132144_5 143224.JQMD01000002_gene234 1.919e-47 179.0 COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia 976|Bacteroidetes H Molybdenum cofactor synthesis domain moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N PJD2_k127_5132144_9 4555.Si018781m 5.492e-09 60.0 KOG3474@1|root,KOG3474@2759|Eukaryota,37WD6@33090|Viridiplantae,3GKBW@35493|Streptophyta,3M0W9@4447|Liliopsida,3IJ47@38820|Poales 35493|Streptophyta C Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin - GO:0006464,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009719,GO:0009725,GO:0009733,GO:0009734,GO:0009755,GO:0009987,GO:0010033,GO:0018315,GO:0019538,GO:0023052,GO:0032870,GO:0036211,GO:0042040,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071310,GO:0071365,GO:0071495,GO:0071704,GO:1901564 2.8.1.12 ko:K03635,ko:K21232 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - ThiS PJD2_k127_5132144_7 204669.Acid345_2057 2.709e-25 113.0 COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,3Y519@57723|Acidobacteria,2JMDU@204432|Acidobacteriia 204432|Acidobacteriia H MoaE protein - - 2.8.1.12 ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE,ThiS PJD2_k127_5132144_6 756272.Plabr_0364 1.632e-31 132.0 COG0746@1|root,COG0746@2|Bacteria,2J411@203682|Planctomycetes 203682|Planctomycetes H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 PJD2_k127_5132144_4 1125863.JAFN01000001_gene2230 1.938e-59 221.0 COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,42RB0@68525|delta/epsilon subdivisions,2WN8G@28221|Deltaproteobacteria 28221|Deltaproteobacteria S membrane - - - - - - - - - - - - - PJD2_k127_5132144_8 518766.Rmar_1833 1.149e-20 100.0 COG4659@1|root,COG4659@2|Bacteria 2|Bacteria C FMN binding rnfG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03612 - - - - ko00000 - - - FMN_bind PJD2_k127_5132144_10 1123261.AXDW01000006_gene2449 2.715e-06 56.0 2E4Z6@1|root,32ZSW@2|Bacteria,1N6U2@1224|Proteobacteria,1T8X1@1236|Gammaproteobacteria,1XBCG@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - PJD2_k127_5132144_2 448385.sce0336 1.231e-112 376.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2WNI2@28221|Deltaproteobacteria,2YU7J@29|Myxococcales 28221|Deltaproteobacteria C cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C,Haem_bd PJD2_k127_5132144_3 237368.SCABRO_01060 4.518e-87 290.0 COG2131@1|root,COG2131@2|Bacteria 2|Bacteria F dCMP deaminase activity comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 PJD2_k127_5132144_1 204669.Acid345_0464 4.333e-234 737.0 COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia 2|Bacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_5132144_0 204669.Acid345_0465 6.693e-270 847.0 COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria,2JHJH@204432|Acidobacteriia 204432|Acidobacteriia Q Ketoacyl-synthetase C-terminal extension - - - - - - - - - - - - ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt PJD2_k127_5148857_0 767434.Fraau_0383 8.925e-50 188.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1X38K@135614|Xanthomonadales 135614|Xanthomonadales J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD PJD2_k127_5148857_1 1379698.RBG1_1C00001G0750 7.147e-23 113.0 COG2143@1|root,COG2143@2|Bacteria 2|Bacteria O COG2143 Thioredoxin-related protein soxS - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - Thioredoxin_2,Thioredoxin_7 PJD2_k127_519726_4 1379698.RBG1_1C00001G1080 2.833e-200 652.0 COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria 2|Bacteria H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 PJD2_k127_519726_9 518766.Rmar_1280 1.134e-13 79.0 COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,4NKF1@976|Bacteroidetes 976|Bacteroidetes Q A domain in the BMP inhibitor chordin and in microbial proteins. - - - - - - - - - - - - CHRD,SusE PJD2_k127_519726_8 479434.Sthe_1384 3.113e-66 232.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,27YBV@189775|Thermomicrobia 189775|Thermomicrobia K FeoA - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA PJD2_k127_519726_7 945713.IALB_0509 3.325e-79 276.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria 2|Bacteria P iron ion homeostasis feoA - - ko:K03322,ko:K03709,ko:K04758 - - - - ko00000,ko02000,ko03000 2.A.55.2.6,2.A.55.3 - - Fe_dep_repr_C,FeoA PJD2_k127_519726_1 385682.AFSL01000102_gene55 6.972e-293 916.0 COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae 976|Bacteroidetes P FeoA - - - - - - - - - - - - FeoA,FeoB_C,FeoB_N,Gate PJD2_k127_519726_6 283942.IL1926 4.703e-144 468.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RQGU@1236|Gammaproteobacteria,2QF13@267893|Idiomarinaceae 1236|Gammaproteobacteria E Membrane dipeptidase (Peptidase family M19) acdP - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 PJD2_k127_519726_3 880073.Calab_3036 3.916e-219 704.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria 2|Bacteria EU peptidase S9 prolyl oligopeptidase active site - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,PD40,Peptidase_S9 PJD2_k127_519726_2 880073.Calab_2352 1.095e-238 743.0 COG0334@1|root,COG0334@2|Bacteria,2NNTY@2323|unclassified Bacteria 2|Bacteria E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase gdhA - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N PJD2_k127_519726_0 945713.IALB_0304 0.0 1110.0 COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria 2|Bacteria T Response regulator, receiver - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PPDK_N,Response_reg,SpoIIE PJD2_k127_519726_5 1499967.BAYZ01000152_gene1435 1.203e-146 476.0 COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria 2|Bacteria G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK PJD2_k127_5204529_9 1457250.BBMO01000002_gene2489 5.156e-26 120.0 COG0421@1|root,arCOG00050@2157|Archaea,2XUEJ@28890|Euryarchaeota,23T1E@183963|Halobacteria 183963|Halobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE - - - - - - - - - - - Spermine_synth PJD2_k127_5204529_10 1267533.KB906735_gene4861 3.96e-22 109.0 COG0265@1|root,COG0265@2|Bacteria,3Y7GN@57723|Acidobacteria,2JM8V@204432|Acidobacteriia 204432|Acidobacteriia O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - - - - - - - - - - - PJD2_k127_5204529_8 1499967.BAYZ01000090_gene4936 2.412e-43 169.0 COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria 2|Bacteria U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 PJD2_k127_5204529_2 572477.Alvin_0339 1.018e-131 432.0 COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,1RQVD@1236|Gammaproteobacteria,1WXGB@135613|Chromatiales 135613|Chromatiales P Citrate transporter - - - - - - - - - - - - CitMHS PJD2_k127_5204529_3 1123371.ATXH01000020_gene476 1.455e-95 325.0 COG0438@1|root,COG0438@2|Bacteria,2GI3U@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria M Glycosyl transferase 4-like domain - - 2.4.1.345,2.4.1.348 ko:K08256,ko:K12995 - - R11702 - ko00000,ko01000,ko01003,ko01005 - GT4 - Glyco_transf_4,Glycos_transf_1 PJD2_k127_5204529_6 1122947.FR7_1481 2.302e-44 184.0 COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4H3T7@909932|Negativicutes 909932|Negativicutes G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 PJD2_k127_5204529_11 237368.SCABRO_03961 1.112e-16 91.0 COG0392@1|root,COG0392@2|Bacteria,2J055@203682|Planctomycetes 203682|Planctomycetes S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM PJD2_k127_5204529_4 706587.Desti_0912 6.112e-69 244.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2WMXX@28221|Deltaproteobacteria,2MQMD@213462|Syntrophobacterales 28221|Deltaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin,cNMP_binding PJD2_k127_5204529_5 1499967.BAYZ01000156_gene556 3.472e-60 226.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.222,2.1.1.64 ko:K00568,ko:K20444 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 PJD2_k127_5204529_12 1379270.AUXF01000006_gene314 1.341e-08 66.0 COG1159@1|root,COG1159@2|Bacteria,1ZU0Y@142182|Gemmatimonadetes 142182|Gemmatimonadetes S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism - - - - - - - - - - - - - PJD2_k127_5204529_13 1122176.KB903543_gene536 1.844e-07 63.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - PKD,SLH,VCBS,fn3 PJD2_k127_5204529_14 1137281.D778_02718 3.944e-07 61.0 COG4886@1|root,COG4886@2|Bacteria,4NWG1@976|Bacteroidetes,1I5Z4@117743|Flavobacteriia 976|Bacteroidetes S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - PJD2_k127_5204529_1 926550.CLDAP_36880 5.043e-141 457.0 COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh PJD2_k127_5204529_0 926550.CLDAP_36890 7.809e-163 519.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi 200795|Chloroflexi C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin porA - 1.2.7.1 ko:K00169,ko:K03737 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034,R10866 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C PJD2_k127_5212206_13 319236.JCM19294_1585 0.0001754 45.0 COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1HWSW@117743|Flavobacteriia,3HJAQ@363408|Nonlabens 976|Bacteroidetes S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE PJD2_k127_5212206_5 1173020.Cha6605_1992 2.097e-61 218.0 COG0546@1|root,COG0546@2|Bacteria,1G6EE@1117|Cyanobacteria 1117|Cyanobacteria S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - - - - - - - - - - HAD_2 PJD2_k127_5212206_3 1123073.KB899242_gene914 8.845e-112 371.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria,1X51U@135614|Xanthomonadales 135614|Xanthomonadales S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH PJD2_k127_5212206_11 1408437.JNJN01000026_gene697 6.235e-11 70.0 COG0760@1|root,COG0760@2|Bacteria,1VE2Y@1239|Firmicutes 1239|Firmicutes M PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_3,SurA_N_3 PJD2_k127_5212206_6 1121015.N789_03890 4.704e-52 192.0 COG0406@1|root,COG0406@2|Bacteria 2|Bacteria G alpha-ribazole phosphatase activity yrgI - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 PJD2_k127_5212206_10 526227.Mesil_0055 1.411e-11 68.0 COG5512@1|root,COG5512@2|Bacteria,1WIYS@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 PJD2_k127_5212206_1 218284.CCDN010000007_gene3787 7.504e-266 833.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim PJD2_k127_5212206_7 595460.RRSWK_07231 2.747e-48 177.0 COG4914@1|root,COG4914@2|Bacteria,2J4D4@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - PJD2_k127_5212206_8 768704.Desmer_1348 1.081e-21 107.0 COG1653@1|root,COG2247@1|root,COG3391@1|root,COG1653@2|Bacteria,COG2247@2|Bacteria,COG3391@2|Bacteria,1V2HJ@1239|Firmicutes,24GGK@186801|Clostridia 186801|Clostridia M Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - - - - - - - - - - Big_2,Flg_new PJD2_k127_5212206_4 314345.SPV1_13177 1.615e-111 371.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria 1224|Proteobacteria M mechanosensitive ion channel ynaI - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel PJD2_k127_5212206_9 1283300.ATXB01000002_gene3058 1.774e-19 90.0 COG0861@1|root,COG0861@2|Bacteria 2|Bacteria P Integral membrane protein TerC family - - - - - - - - - - - - PGPGW PJD2_k127_5212206_2 264462.Bd2609 1.678e-138 468.0 COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2MSPQ@213481|Bdellovibrionales,2WUJ6@28221|Deltaproteobacteria 213481|Bdellovibrionales P E1-E2 ATPase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,Hydrolase PJD2_k127_5212206_12 862908.BMS_1402 1.691e-08 59.0 COG3197@1|root,COG3197@2|Bacteria,1PUQX@1224|Proteobacteria,433SW@68525|delta/epsilon subdivisions,2MTDZ@213481|Bdellovibrionales,2WYFW@28221|Deltaproteobacteria 213481|Bdellovibrionales P cytochrome oxidase maturation protein cbb3-type ccoS - - - - - - - - - - - FixS PJD2_k127_5212206_0 264462.Bd2611 2.032e-289 897.0 COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2MSPA@213481|Bdellovibrionales,2WM27@28221|Deltaproteobacteria 213481|Bdellovibrionales C Belongs to the heme-copper respiratory oxidase family - - 1.9.3.1 ko:K00404,ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1,FixO PJD2_k127_522524_2 1047013.AQSP01000067_gene2199 2.961e-121 403.0 COG3379@1|root,COG3379@2|Bacteria,2NQEW@2323|unclassified Bacteria 2|Bacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_522524_0 502025.Hoch_2285 1.42e-204 657.0 COG0696@1|root,COG3379@1|root,COG0696@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42PUB@68525|delta/epsilon subdivisions,2WMH5@28221|Deltaproteobacteria 28221|Deltaproteobacteria G PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_522524_1 1047013.AQSP01000067_gene2201 1.365e-183 597.0 COG3379@1|root,COG3379@2|Bacteria,2NQIG@2323|unclassified Bacteria 2|Bacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_522524_4 1047013.AQSP01000067_gene2202 5.129e-16 80.0 2EQW9@1|root,33IG2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_522524_3 1047013.AQSP01000067_gene2203 6.738e-29 126.0 2DZX2@1|root,32VM6@2|Bacteria,2NRAT@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_5233782_1 1122226.AUHX01000001_gene558 1.773e-85 308.0 COG3202@1|root,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia 976|Bacteroidetes C TLC ATP/ADP transporter - - - ko:K03301 - - - - ko00000 2.A.12 - - TLC,cNMP_binding PJD2_k127_5233782_2 483219.LILAB_20575 6.576e-16 90.0 COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N PJD2_k127_5233782_0 880073.Calab_0513 1.124e-117 400.0 2C3GN@1|root,31EWU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_5233782_3 452637.Oter_1909 1.748e-10 70.0 COG3595@1|root,COG3595@2|Bacteria,46W0J@74201|Verrucomicrobia 74201|Verrucomicrobia S Putative adhesin - - - - - - - - - - - - DUF4097 PJD2_k127_5263124_1 1499967.BAYZ01000159_gene546 6.717e-132 459.0 2EYYT@1|root,33S5J@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_5263124_4 1485544.JQKP01000001_gene930 7.248e-21 100.0 COG3070@1|root,COG3070@2|Bacteria,1PJWV@1224|Proteobacteria,2W88N@28216|Betaproteobacteria,44WJI@713636|Nitrosomonadales 28216|Betaproteobacteria K TfoX N-terminal domain - - - ko:K07343 - - - - ko00000 - - - TfoX_N PJD2_k127_5263124_2 1142394.PSMK_27880 8.166e-48 188.0 COG2017@1|root,COG2017@2|Bacteria,2J49D@203682|Planctomycetes 203682|Planctomycetes G converts alpha-aldose to the beta-anomer - - - - - - - - - - - - - PJD2_k127_5263124_0 1303518.CCALI_02200 8.315e-238 747.0 COG4799@1|root,COG4799@2|Bacteria 2|Bacteria I CoA carboxylase activity mccB - 2.1.3.15,6.4.1.3,6.4.1.4,6.4.1.5 ko:K01969,ko:K13778,ko:K15052 ko00280,ko00281,ko00720,ko01100,ko01200,map00280,map00281,map00720,map01100,map01200 M00036,M00376 R01859,R03494,R04138 RC00097,RC00367,RC00609,RC00942 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_3290 Carboxyl_trans PJD2_k127_5263124_3 259536.Psyc_0310 6.053e-27 113.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,3NIIF@468|Moraxellaceae 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family liuC - 4.2.1.18,5.3.3.18 ko:K13766,ko:K15866 ko00280,ko00360,ko01100,ko01120,map00280,map00360,map01100,map01120 M00036 R02085,R09837,R09839 RC00004,RC00326,RC02416,RC02689,RC03003 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 PJD2_k127_5312287_1 1385519.N801_12900 8.529e-13 76.0 COG5360@1|root,COG5360@2|Bacteria,2GX24@201174|Actinobacteria 201174|Actinobacteria S Heparinase II/III N-terminus - - - - - - - - - - - - Hepar_II_III,Hepar_II_III_N PJD2_k127_5312287_0 880073.Calab_1973 8.921e-20 104.0 COG2911@1|root,COG4447@1|root,COG2911@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 3.2.1.4 ko:K01179,ko:K21449 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko02000 1.B.40.2 GH5,GH9 - CBM_X2,fn3 PJD2_k127_531460_3 1499967.BAYZ01000050_gene2876 7.552e-12 68.0 COG0526@1|root,COG0526@2|Bacteria,2NQ68@2323|unclassified Bacteria 2|Bacteria CO COG0526, thiol-disulfide isomerase and thioredoxins resA_1 - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin PJD2_k127_531460_2 595460.RRSWK_03132 2.567e-62 222.0 COG0785@1|root,COG0785@2|Bacteria,2J2ZI@203682|Planctomycetes 203682|Planctomycetes O Cytochrome C biogenesis protein transmembrane region - - - - - - - - - - - - DsbD_2 PJD2_k127_531460_1 1499967.BAYZ01000019_gene6264 7.839e-72 249.0 COG0546@1|root,COG0546@2|Bacteria,2NPKQ@2323|unclassified Bacteria 2|Bacteria S Haloacid dehalogenase-like hydrolase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 PJD2_k127_531460_0 497964.CfE428DRAFT_1013 1.139e-98 331.0 COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia 74201|Verrucomicrobia P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer PJD2_k127_533717_10 521098.Aaci_1056 4.012e-06 53.0 COG1807@1|root,COG1807@2|Bacteria,1UYMG@1239|Firmicutes,4HB8M@91061|Bacilli 91061|Bacilli M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 PJD2_k127_533717_0 1444309.JAQG01000019_gene564 9.174e-220 695.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,2750X@186822|Paenibacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family rocA - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh PJD2_k127_533717_6 1123376.AUIU01000014_gene599 6.854e-26 121.0 COG0824@1|root,COG0824@2|Bacteria,3J1EV@40117|Nitrospirae 40117|Nitrospirae S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT PJD2_k127_533717_8 266117.Rxyl_0794 3.722e-15 90.0 COG1254@1|root,COG1254@2|Bacteria,2IT6J@201174|Actinobacteria,4CTJ9@84995|Rubrobacteria 84995|Rubrobacteria C Acylphosphatase - - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase PJD2_k127_533717_7 671143.DAMO_3152 2.135e-15 81.0 COG1371@1|root,COG1371@2|Bacteria,2NPX9@2323|unclassified Bacteria 2|Bacteria S Archease protein family (MTH1598/TM1083) - - - - - - - - - - - - Archease PJD2_k127_533717_4 748449.Halha_2386 5.036e-55 207.0 COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia 186801|Clostridia S membrane protein involved in the export of O-antigen and teichoic acid - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C PJD2_k127_533717_9 717606.PaecuDRAFT_1531 1.011e-12 74.0 COG2244@1|root,COG2244@2|Bacteria,1V929@1239|Firmicutes,4HKDX@91061|Bacilli 91061|Bacilli S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C PJD2_k127_533717_1 1121405.dsmv_0379 1.508e-207 661.0 COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales 28221|Deltaproteobacteria P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - CBS,TrkA_C,Voltage_CLC PJD2_k127_533717_2 679926.Mpet_1361 6.112e-187 599.0 COG0171@1|root,COG0388@1|root,arCOG00062@2157|Archaea,arCOG00069@2157|Archaea,2XUJI@28890|Euryarchaeota,2NBHN@224756|Methanomicrobia 224756|Methanomicrobia H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase PJD2_k127_533717_5 1123274.KB899417_gene2063 5.447e-50 184.0 COG4843@1|root,COG4843@2|Bacteria,2JASX@203691|Spirochaetes 203691|Spirochaetes S Uncharacterized protein conserved in bacteria (DUF2179) - - - - - - - - - - - - DUF2179 PJD2_k127_533717_3 880073.Calab_0811 1.02e-70 240.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria 2|Bacteria EU peptidase S9 prolyl oligopeptidase active site - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - PD40,Peptidase_S9 PJD2_k127_5457674_7 84531.JMTZ01000166_gene1270 1.311e-33 139.0 COG2968@1|root,COG2968@2|Bacteria 2|Bacteria S cellular response to heat - - - ko:K09807 - - - - ko00000 - - - SIMPL PJD2_k127_5457674_1 518766.Rmar_2132 1.199e-153 497.0 COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1FIYR@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Peptidase dimerisation domain dapE - - - - - - - - - - - M20_dimer,Peptidase_M20 PJD2_k127_5457674_6 1089547.KB913013_gene4439 2.88e-34 137.0 COG3678@1|root,COG3678@2|Bacteria,4NXZA@976|Bacteroidetes 976|Bacteroidetes NPTU ATP-independent chaperone mediated protein folding - - - - - - - - - - - - - PJD2_k127_5457674_2 204669.Acid345_1455 2.834e-147 497.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia 204432|Acidobacteriia KLT Tetratricopeptide repeats - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C PJD2_k127_5457674_0 1379698.RBG1_1C00001G0607 2.51e-180 591.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_2,TPR_8 PJD2_k127_5457674_5 204669.Acid345_2395 2.189e-34 141.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_2,TPR_8 PJD2_k127_5457674_4 1117319.PSPO_14244 3.212e-42 159.0 COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,2Q1G4@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S enzyme related to lactoylglutathione lyase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase PJD2_k127_5469813_13 234267.Acid_3938 3.248e-15 81.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 PJD2_k127_5469813_1 234267.Acid_7393 5.004e-184 606.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria 57723|Acidobacteria KLTU WD40 domain protein beta Propeller - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase PJD2_k127_5469813_9 204669.Acid345_0263 2.052e-39 163.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia 204432|Acidobacteriia KLTU Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase PJD2_k127_5469813_0 204669.Acid345_4118 5.791e-243 779.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia 57723|Acidobacteria KLTU Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase PJD2_k127_5469813_3 1047013.AQSP01000134_gene1338 1.271e-135 449.0 COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria 2|Bacteria H Trimethylamine methyltransferase (MTTB) - - 2.1.1.250 ko:K14083 ko00680,ko01120,ko01200,map00680,map01120,map01200 M00563 R09124,R10016 RC00035,RC00732,RC01144,RC02984 ko00000,ko00001,ko00002,ko01000 - - - MTTB PJD2_k127_5469813_12 555088.DealDRAFT_2256 4.355e-19 101.0 COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia 186801|Clostridia E vitamin B12 dependent methionine synthase, activation metH2 - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Met_synt_B12 PJD2_k127_5469813_6 177437.HRM2_43970 1.218e-65 238.0 COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,43BU7@68525|delta/epsilon subdivisions,2X757@28221|Deltaproteobacteria,2MJ6M@213118|Desulfobacterales 28221|Deltaproteobacteria E Homocysteine S-methyltransferase - - 1.5.1.20,2.1.1.10,2.1.1.13 ko:K00297,ko:K00547,ko:K00548 ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523 M00017,M00377 R00650,R00946,R01224,R07168,R09365 RC00003,RC00035,RC00081,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - S-methyl_trans PJD2_k127_5469813_7 1047013.AQSP01000134_gene1339 4.806e-55 203.0 COG5012@1|root,COG5012@2|Bacteria,2NQTJ@2323|unclassified Bacteria 2|Bacteria S B12 binding domain - - - ko:K14084 ko00680,ko01120,ko01200,map00680,map01120,map01200 M00563 R09124 RC00035,RC00732,RC02984 ko00000,ko00001,ko00002 - - - B12-binding,B12-binding_2 PJD2_k127_5469813_14 1121930.AQXG01000004_gene2828 4.123e-15 89.0 COG2911@1|root,COG2911@2|Bacteria,4PPNA@976|Bacteroidetes 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - PJD2_k127_5469813_11 926550.CLDAP_33700 2.011e-30 139.0 COG2234@1|root,COG2234@2|Bacteria,2G8V6@200795|Chloroflexi 200795|Chloroflexi S Peptidase family M28 - - 3.4.11.10 ko:K05994 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M28 PJD2_k127_5469813_10 1304885.AUEY01000095_gene2623 3.353e-35 139.0 COG2010@1|root,COG2010@2|Bacteria,1NKKK@1224|Proteobacteria,42UAC@68525|delta/epsilon subdivisions,2WXVI@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Haem-binding domain - - - - - - - - - - - - Haem_bd PJD2_k127_5469813_8 861299.J421_0735 6.951e-40 173.0 COG0457@1|root,COG0457@2|Bacteria 861299.J421_0735|- S peptidyl-tyrosine sulfation - - - ko:K13992 - - - - ko00000,ko00194 - - - - PJD2_k127_5469813_4 234267.Acid_1142 6.243e-93 345.0 COG4409@1|root,COG4409@2|Bacteria,3Y8VS@57723|Acidobacteria 57723|Acidobacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - PJD2_k127_5469813_15 459349.CLOAM0891 4.388e-11 78.0 COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y PJD2_k127_5469813_2 1511.CLOST_1222 7.242e-164 528.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25QPU@186804|Peptostreptococcaceae 186801|Clostridia E Aminotransferase aspB - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - iHN637.CLJU_RS10450 Aminotran_1_2 PJD2_k127_5469813_5 1232410.KI421413_gene485 6.508e-76 263.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria,43UFH@69541|Desulfuromonadales 28221|Deltaproteobacteria Q Dienelactone hydrolase family - - - - - - - - - - - - DLH PJD2_k127_5508307_1 1122599.AUGR01000010_gene1068 2.652e-06 59.0 COG1073@1|root,COG5360@1|root,COG1073@2|Bacteria,COG5360@2|Bacteria,1R0HR@1224|Proteobacteria,1SA7M@1236|Gammaproteobacteria,1XPQT@135619|Oceanospirillales 135619|Oceanospirillales S Heparinase II/III-like protein - - - - - - - - - - - - Hepar_II_III PJD2_k127_5508307_0 1048983.EL17_01575 1.429e-36 148.0 COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator, Crp Fnr family - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding PJD2_k127_5536199_1 1382359.JIAL01000001_gene375 1.065e-28 124.0 COG1560@1|root,COG1560@2|Bacteria,3Y2RW@57723|Acidobacteria,2JIMS@204432|Acidobacteriia 204432|Acidobacteriia M lipid A biosynthesis acyltransferase - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans PJD2_k127_5536199_0 401526.TcarDRAFT_1341 5.299e-88 304.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1TQ04@1239|Firmicutes,4H28I@909932|Negativicutes 909932|Negativicutes M Belongs to the SIS family. GutQ KpsF subfamily kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS PJD2_k127_5536199_2 224324.aq_085 1.674e-09 60.0 COG2877@1|root,COG2877@2|Bacteria,2G4G9@200783|Aquificae 200783|Aquificae M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 PJD2_k127_5542943_6 639282.DEFDS_1264 2.917e-09 60.0 COG0848@1|root,COG0848@2|Bacteria,2GFX6@200930|Deferribacteres 200930|Deferribacteres U Biopolymer transport protein ExbD TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD PJD2_k127_5542943_3 880073.Calab_1219 8.021e-43 164.0 COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria 2|Bacteria U MotA/TolQ/ExbB proton channel family exbB2 - - ko:K03561,ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 - - MotA_ExbB PJD2_k127_5542943_4 880073.Calab_1220 9.25e-19 98.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity tonB3 - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_2,TonB_C PJD2_k127_5542943_1 935948.KE386494_gene413 3.401e-102 345.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,42F3H@68295|Thermoanaerobacterales 186801|Clostridia P PFAM ABC transporter related msmX - 3.6.3.20 ko:K05816,ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.3 - - ABC_tran,TOBE,TOBE_2 PJD2_k127_5542943_0 1191523.MROS_2755 5.301e-159 513.0 COG0160@1|root,COG0160@2|Bacteria 2|Bacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family lat - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 ko:K00821,ko:K03918,ko:K07250,ko:K13524 ko00220,ko00250,ko00280,ko00300,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,ko04727,map00220,map00250,map00280,map00300,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230,map04727 M00016,M00027,M00028,M00845 R00457,R00908,R01648,R02283,R04188,R04475 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - iNJ661.Rv3290c Aminotran_3 PJD2_k127_5542943_2 797114.C475_05350 1.424e-61 232.0 COG1574@1|root,arCOG00691@2157|Archaea,2XUUZ@28890|Euryarchaeota,23SFX@183963|Halobacteria 183963|Halobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 PJD2_k127_5542943_5 459349.CLOAM0583 2.124e-17 85.0 COG1404@1|root,COG1470@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,2NREM@2323|unclassified Bacteria 2|Bacteria O Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CARDB,Calx-beta,CarboxypepD_reg,DUF11,FlgD_ig,HYR,PKD,PPC,SLH,VCBS,fn3 PJD2_k127_555538_7 1535422.ND16A_1891 2.692e-07 53.0 COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria,2Q8AB@267889|Colwelliaceae 1236|Gammaproteobacteria S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235 PJD2_k127_555538_3 1396141.BATP01000025_gene931 6.159e-81 280.0 COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Dimerisation domain of Zinc Transporter - - - - - - - - - - - - Cation_efflux,ZT_dimer PJD2_k127_555538_5 533247.CRD_02150 8.687e-15 86.0 COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria 1117|Cyanobacteria E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL PJD2_k127_555538_6 1172188.KB911820_gene3085 5.048e-12 73.0 28RB9@1|root,2ZDQU@2|Bacteria,2GZQK@201174|Actinobacteria,4FIZG@85021|Intrasporangiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - PJD2_k127_555538_0 404589.Anae109_1606 5.295e-200 632.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,437ZU@68525|delta/epsilon subdivisions,2X39R@28221|Deltaproteobacteria,2YV0T@29|Myxococcales 28221|Deltaproteobacteria C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 PJD2_k127_555538_4 1123242.JH636434_gene5626 1.023e-25 112.0 COG4886@1|root,COG5426@1|root,COG4886@2|Bacteria,COG5426@2|Bacteria 2|Bacteria D von Willebrand factor, type A - - - - - - - - - - - - DUF285,Flg_new,LRR_5,LRR_6 PJD2_k127_555538_1 42256.RradSPS_0888 1.716e-172 556.0 COG1115@1|root,COG1115@2|Bacteria,2GIU2@201174|Actinobacteria 201174|Actinobacteria E amino acid carrier protein alaP - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp PJD2_k127_555538_2 1122604.JONR01000057_gene3533 2.605e-85 313.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1RS3D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S VIT family - - - - - - - - - - - - VIT1 PJD2_k127_557652_9 2754.EH55_05870 2.331e-19 89.0 COG0590@1|root,COG0590@2|Bacteria,3TB5H@508458|Synergistetes 508458|Synergistetes FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam PJD2_k127_557652_11 420662.Mpe_A3352 3.33e-08 59.0 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2VXYJ@28216|Betaproteobacteria,1KMVN@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Protein of unknown function (DUF1289) - - - ko:K06938 - - - - ko00000 - - - DUF1289 PJD2_k127_557652_10 1121859.KB890738_gene3304 1.657e-12 79.0 COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,47PNV@768503|Cytophagia 976|Bacteroidetes M Surface antigen - - - - - - - - - - - - Bac_surface_Ag PJD2_k127_557652_0 1254432.SCE1572_37590 2.825e-107 363.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales 28221|Deltaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - - PJD2_k127_557652_12 1530186.JQEY01000001_gene893 7.376e-08 56.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Resolvase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom PJD2_k127_557652_1 316067.Geob_0378 1.882e-102 355.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria 28221|Deltaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 PJD2_k127_557652_7 999411.HMPREF1092_00042 5.064e-26 111.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,36JG6@31979|Clostridiaceae 186801|Clostridia S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd PJD2_k127_557652_4 1089553.Tph_c28990 3.67e-63 224.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,42F7S@68295|Thermoanaerobacterales 186801|Clostridia L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 PJD2_k127_557652_5 379066.GAU_1115 7.222e-38 148.0 COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Roadblock/LC7 domain - - - - - - - - - - - - Robl_LC7 PJD2_k127_557652_2 1232410.KI421424_gene1860 1.934e-85 287.0 COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43RZJ@69541|Desulfuromonadales 28221|Deltaproteobacteria S ADP-ribosylation factor family mglA - - ko:K06883 - - - - ko00000 - - - Arf,Ras PJD2_k127_557652_8 880073.Calab_1192 2.428e-24 111.0 COG1267@1|root,COG1267@2|Bacteria,2NPTB@2323|unclassified Bacteria 2|Bacteria I Phosphatidylglycerophosphatase A pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iAF987.Gmet_0195,iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA PJD2_k127_557652_6 1313301.AUGC01000019_gene725 2.158e-35 142.0 COG0668@1|root,COG0668@2|Bacteria,4NEPW@976|Bacteroidetes 976|Bacteroidetes M mechanosensitive ion channel - - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel PJD2_k127_5613578_5 1267535.KB906767_gene3997 1.758e-08 65.0 28K54@1|root,2Z9TW@2|Bacteria,3Y3Z7@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - PJD2_k127_5613578_6 682795.AciX8_3190 7.977e-05 49.0 2EFR0@1|root,339H2@2|Bacteria,3Y5M9@57723|Acidobacteria,2JJPZ@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - PJD2_k127_5613578_4 1125863.JAFN01000001_gene3014 3.041e-10 74.0 COG3088@1|root,COG3088@2|Bacteria,1Q682@1224|Proteobacteria,432K1@68525|delta/epsilon subdivisions,2WXAZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Cytochrome C biogenesis protein - - - ko:K02200 - - - - ko00000 - - - CcmH PJD2_k127_5613578_0 240015.ACP_2781 1.299e-185 601.0 COG1138@1|root,COG1138@2|Bacteria,3Y40N@57723|Acidobacteria,2JHQR@204432|Acidobacteriia 204432|Acidobacteriia O PFAM Cytochrome c assembly protein - - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm PJD2_k127_5613578_3 1382359.JIAL01000001_gene2248 2.491e-30 125.0 COG2332@1|root,COG2332@2|Bacteria,3Y57C@57723|Acidobacteria,2JJR8@204432|Acidobacteriia 204432|Acidobacteriia O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH - - - ko:K02197 - - - - ko00000 - - - CcmE PJD2_k127_5613578_1 338966.Ppro_0096 1.091e-124 408.0 COG2512@1|root,COG3177@1|root,COG2512@2|Bacteria,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,42PWW@68525|delta/epsilon subdivisions,2WJM6@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM filamentation induced by cAMP protein Fic - - - - - - - - - - - - Fic PJD2_k127_5613578_2 926550.CLDAP_36890 1.662e-121 394.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi 200795|Chloroflexi C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin porA - 1.2.7.1 ko:K00169,ko:K03737 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034,R10866 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C PJD2_k127_5622058_0 63737.Npun_R0666 9.15e-15 84.0 COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1HQDG@1161|Nostocales 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TIR_2,TPR_1,TPR_11,TPR_2,TPR_8 PJD2_k127_5622058_1 1191523.MROS_0050 2.8e-07 63.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - - PJD2_k127_5651591_0 886293.Sinac_0199 8.987e-139 451.0 COG0076@1|root,COG0076@2|Bacteria 2|Bacteria E glutamate decarboxylase activity - - - - - - - - - - - - Pyridoxal_deC PJD2_k127_5651591_1 1267535.KB906767_gene666 2.171e-40 159.0 28NPC@1|root,2ZBPA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_5651591_2 999141.GME_16087 6.437e-14 78.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XITW@135619|Oceanospirillales 135619|Oceanospirillales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N PJD2_k127_5657916_2 1519464.HY22_08950 1.901e-07 57.0 COG2091@1|root,COG2091@2|Bacteria 2|Bacteria H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 PJD2_k127_5657916_0 945713.IALB_3108 6.061e-50 184.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c cccE - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 PJD2_k127_5657916_1 637905.SVI_0202 3.104e-42 159.0 COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,2QB1M@267890|Shewanellaceae 1236|Gammaproteobacteria C PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase PJD2_k127_5750637_5 761193.Runsl_4856 0.0001777 46.0 COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,47M84@768503|Cytophagia 976|Bacteroidetes O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C PJD2_k127_5750637_0 580327.Tthe_0883 3.135e-167 535.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,42EU3@68295|Thermoanaerobacterales 186801|Clostridia O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX PJD2_k127_5750637_3 648996.Theam_0136 1.946e-84 286.0 COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae 200783|Aquificae O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease PJD2_k127_5750637_4 204669.Acid345_1561 6.139e-51 199.0 COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria,2JIVB@204432|Acidobacteriia 204432|Acidobacteriia O Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N PJD2_k127_5750637_1 1379698.RBG1_1C00001G0516 5.877e-133 432.0 COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria 2|Bacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh PJD2_k127_5750637_2 880073.Calab_1752 6.502e-106 349.0 COG1960@1|root,COG1960@2|Bacteria,2NQE6@2323|unclassified Bacteria 2|Bacteria I Acyl-CoA dehydrogenase, C-terminal domain gcdH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_579920_4 944479.JQLX01000014_gene1649 4.309e-26 113.0 COG1321@1|root,COG1321@2|Bacteria,1RHIK@1224|Proteobacteria,42SAD@68525|delta/epsilon subdivisions,2X6HJ@28221|Deltaproteobacteria,2M76C@213113|Desulfurellales 28221|Deltaproteobacteria K Helix-turn-helix diphteria tox regulatory element - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress PJD2_k127_579920_3 1191523.MROS_2770 1.024e-30 127.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding usp-3 - - - - - - - - - - - Usp PJD2_k127_579920_2 1379698.RBG1_1C00001G0764 7.873e-31 126.0 COG1959@1|root,COG1959@2|Bacteria,2NQ8B@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulator, BadM Rrf2 family - - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 PJD2_k127_579920_0 1123073.KB899241_gene2287 2.235e-111 373.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1X7MH@135614|Xanthomonadales 135614|Xanthomonadales E Glycine cleavage T-protein C-terminal barrel domain - - - - - - - - - - - - GCV_T,GCV_T_C PJD2_k127_579920_1 204669.Acid345_1270 3.99e-54 195.0 COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia 204432|Acidobacteriia Q Flavin containing amine oxidoreductase - - - - - - - - - - - - NAD_binding_8 PJD2_k127_5810716_1 335543.Sfum_0219 4.724e-26 114.0 COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2MRX9@213462|Syntrophobacterales 28221|Deltaproteobacteria O Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_5810716_2 583355.Caka_1220 8.452e-25 117.0 COG0457@1|root,COG3379@1|root,COG3551@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria,COG3551@2|Bacteria,46URB@74201|Verrucomicrobia 74201|Verrucomicrobia O Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_5810716_0 760568.Desku_3292 3.473e-183 587.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,2602C@186807|Peptococcaceae 186801|Clostridia G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N PJD2_k127_5815819_2 1379698.RBG1_1C00001G1235 8.561e-11 75.0 COG1470@1|root,COG1470@2|Bacteria 2|Bacteria S cell adhesion involved in biofilm formation - - - - - - - - - - - - CarbopepD_reg_2 PJD2_k127_5815819_0 1379698.RBG1_1C00001G0497 3.853e-29 127.0 COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria 2|Bacteria U MotA/TolQ/ExbB proton channel family tolQ - - ko:K03561,ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.1,1.A.30.2.2 - - MotA_ExbB PJD2_k127_5815819_1 289376.THEYE_A0958 2.626e-25 117.0 COG0848@1|root,COG0848@2|Bacteria,3J0T6@40117|Nitrospirae 40117|Nitrospirae U Biopolymer transport protein ExbD/TolR - - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD PJD2_k127_5818580_1 330214.NIDE3623 3.909e-52 189.0 COG0656@1|root,COG0656@2|Bacteria 2|Bacteria S aldo-keto reductase (NADP) activity ytbE - - - - - - - - - - - Aldo_ket_red,DUF4157 PJD2_k127_5818580_0 1237149.C900_02873 2.898e-81 280.0 COG0500@1|root,COG2226@2|Bacteria,4P2IZ@976|Bacteroidetes 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - - PJD2_k127_5818580_2 290315.Clim_1053 2.038e-43 166.0 COG1280@1|root,COG1280@2|Bacteria 2|Bacteria E homoserine transmembrane transporter activity chpE - - ko:K06600,ko:K06895 - - - - ko00000,ko02000,ko02035 2.A.75.1,2.A.76 - - LysE PJD2_k127_5818580_4 1210884.HG799464_gene11229 5.141e-17 86.0 COG0500@1|root,COG2226@2|Bacteria,2IYB6@203682|Planctomycetes 203682|Planctomycetes Q Methylase involved in ubiquinone menaquinone - - - - - - - - - - - - Methyltransf_31 PJD2_k127_5818580_3 1122221.JHVI01000004_gene147 1.883e-38 147.0 2CMS6@1|root,32SFE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DinB_2 PJD2_k127_5825242_1 880073.Calab_3241 4.599e-87 294.0 COG0439@1|root,COG0439@2|Bacteria,2NNWM@2323|unclassified Bacteria 2|Bacteria I acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 PJD2_k127_5825242_0 1125863.JAFN01000001_gene3585 7.283e-136 463.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria 28221|Deltaproteobacteria D PFAM cell divisionFtsK SpoIIIE ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma PJD2_k127_5825242_2 1009370.ALO_19952 0.0003323 51.0 COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,4H28W@909932|Negativicutes 909932|Negativicutes H Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 PJD2_k127_5835966_3 1150469.RSPPHO_02458 1.262e-25 109.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,2JRPM@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 PJD2_k127_5835966_2 880073.Calab_2041 7.545e-90 317.0 COG2239@1|root,COG2239@2|Bacteria,2NP6V@2323|unclassified Bacteria 2|Bacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N,PRC PJD2_k127_5835966_5 1121087.AUCK01000004_gene1176 6.329e-15 84.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,1ZAUA@1386|Bacillus 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N PJD2_k127_5835966_1 1121423.JONT01000001_gene1997 2.13e-126 411.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,24AU0@186801|Clostridia,2604H@186807|Peptococcaceae 186801|Clostridia J PFAM glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e PJD2_k127_5835966_0 1408254.T458_03485 1.495e-127 446.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,26S3M@186822|Paenibacillaceae 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f PJD2_k127_5835966_4 880073.Calab_0921 1.78e-22 115.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 PJD2_k127_5837546_5 1379698.RBG1_1C00001G1218 4.94e-43 174.0 COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria 2|Bacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase,TPR_8 PJD2_k127_5837546_11 1246995.AFR_00200 0.0001579 54.0 COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2ICR5@201174|Actinobacteria,4D8VU@85008|Micromonosporales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_31,TPR_12 PJD2_k127_5837546_1 373994.Riv7116_3206 2.055e-122 408.0 COG0534@1|root,COG0534@2|Bacteria,1G2M4@1117|Cyanobacteria,1HQ3N@1161|Nostocales 1117|Cyanobacteria V MatE - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE PJD2_k127_5837546_6 1089550.ATTH01000001_gene1531 6.593e-41 177.0 COG2911@1|root,COG3210@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,4NTNN@976|Bacteroidetes 976|Bacteroidetes U Parallel beta-helix repeats - - - - - - - - - - - - CHU_C,LTD PJD2_k127_5837546_0 765420.OSCT_2114 1.688e-129 466.0 COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia 32061|Chloroflexia Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS PJD2_k127_5837546_9 96561.Dole_1704 3.879e-24 120.0 COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales 1224|Proteobacteria P Parallel beta-helix repeats - - - - - - - - - - - - - PJD2_k127_5837546_10 1191523.MROS_1825 1.643e-15 92.0 COG4412@1|root,COG4447@1|root,COG4412@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - DUF4859,FlgD_ig,PSII_BNR PJD2_k127_5837546_12 1151117.AJLF01000001_gene1492 0.0007662 50.0 arCOG02559@1|root,arCOG03264@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci 183968|Thermococci KLT Serine threonine protein kinase - - - - - - - - - - - - DUF5122,PEGA PJD2_k127_5837546_8 489825.LYNGBM3L_73570 7.943e-30 138.0 COG0683@1|root,COG1672@1|root,COG0683@2|Bacteria,COG1672@2|Bacteria,1G4E9@1117|Cyanobacteria,1HAXK@1150|Oscillatoriales 1117|Cyanobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - AAA_16,Peripla_BP_6,TPR_16 PJD2_k127_5837546_3 929712.KI912613_gene1137 4.467e-50 203.0 COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria 84995|Rubrobacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase PJD2_k127_5837546_7 671143.DAMO_1046 1.949e-31 128.0 COG4747@1|root,COG4747@2|Bacteria,2NR4R@2323|unclassified Bacteria 2|Bacteria S ACT domain protein hom - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 ko:K00003,ko:K00058,ko:K01754,ko:K04767 ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00017,M00018,M00020,M00570 R00220,R00996,R01513,R01773,R01775 RC00031,RC00087,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3 PJD2_k127_5837546_2 945713.IALB_0147 2.748e-51 208.0 COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - 3.4.11.10,3.4.21.50 ko:K01337,ko:K05994,ko:K20276 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002 - - - DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C PJD2_k127_5837546_4 1392490.JHZX01000001_gene3302 5.524e-45 179.0 COG0265@1|root,COG1572@1|root,COG3291@1|root,COG0265@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NIM1@976|Bacteroidetes,1I0WD@117743|Flavobacteriia 976|Bacteroidetes E Pregnancy-associated plasma protein-A - - - - - - - - - - - - MAM,PKD,Peptidase_M43,Reprolysin_3 PJD2_k127_5887876_0 1297742.A176_01478 6.991e-84 290.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YTVN@29|Myxococcales 28221|Deltaproteobacteria K Bacterial regulatory protein, Fis family - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,HTH_8,Pkinase,PocR,Sigma54_activat PJD2_k127_5887876_2 526227.Mesil_0204 2.569e-50 186.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 PJD2_k127_5887876_3 861299.J421_2657 1.001e-31 143.0 COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes 2|Bacteria N domain, Protein - - 3.2.1.4,3.4.17.14 ko:K01179,ko:K07260,ko:K13735 ko00500,ko00550,ko01100,ko01502,ko02020,ko05100,map00500,map00550,map01100,map01502,map02020,map05100 M00651 R06200,R11307,R11308 - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - GH5,GH9 - Big_1,Big_2,Glug,IAT_beta,Invasin_D3,LysM,Mfa_like_1,SLH PJD2_k127_5887876_1 204669.Acid345_0751 7.769e-80 281.0 COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JICQ@204432|Acidobacteriia 204432|Acidobacteriia T PFAM Response regulator receiver domain - - - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_5913221_4 357276.EL88_19965 1.246e-25 111.0 COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,2FN72@200643|Bacteroidia,4AK8J@815|Bacteroidaceae 976|Bacteroidetes G pfkB family ydjH_1 - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB PJD2_k127_5913221_5 76114.ebA3319 4.608e-18 92.0 COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,2VRNX@28216|Betaproteobacteria,2KWBG@206389|Rhodocyclales 206389|Rhodocyclales K Transcriptional regulatory protein, C terminal colR - - - - - - - - - - - Response_reg,Trans_reg_C PJD2_k127_5913221_2 926569.ANT_25700 1.727e-30 138.0 COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA PJD2_k127_5913221_6 1329516.JPST01000055_gene840 0.0002748 54.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HDXV@91061|Bacilli,27AUJ@186824|Thermoactinomycetaceae 91061|Bacilli T PAS fold atoS - 2.7.13.3 ko:K07710 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9 PJD2_k127_5913221_1 649638.Trad_2575 1.276e-106 354.0 COG1087@1|root,COG1087@2|Bacteria,1WMCP@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase PJD2_k127_5913221_0 1209989.TepiRe1_1777 6.82e-270 867.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales 186801|Clostridia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran PJD2_k127_5913221_3 1313304.CALK_1490 2.522e-30 126.0 COG1694@1|root,COG3956@2|Bacteria 2|Bacteria E TIGRFAM MazG family protein mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 ko:K02428,ko:K02499,ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323 RC00002 ko00000,ko00001,ko01000,ko03036 - - iJN678.sll1005 MazG PJD2_k127_594645_1 243231.GSU1331 3.293e-81 287.0 COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,43SU3@69541|Desulfuromonadales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07798,ko:K15727 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1,8.A.1.2.1 - - DUF3347,HlyD_D23 PJD2_k127_594645_4 237368.SCABRO_01554 1.472e-45 181.0 COG1538@1|root,COG1538@2|Bacteria,2IZPU@203682|Planctomycetes 203682|Planctomycetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP PJD2_k127_594645_0 1047013.AQSP01000105_gene1461 1.653e-248 795.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria 2|Bacteria EU peptidase S9 prolyl oligopeptidase active site dap2 - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 PJD2_k127_594645_8 1380384.JADN01000004_gene2065 1.14e-29 125.0 COG2318@1|root,COG2318@2|Bacteria,4NSEY@976|Bacteroidetes,1I2YX@117743|Flavobacteriia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 PJD2_k127_594645_5 1121957.ATVL01000006_gene3187 2.289e-45 175.0 COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia 976|Bacteroidetes L pfam nudix - - - - - - - - - - - - NUDIX PJD2_k127_594645_7 383372.Rcas_4224 5.044e-36 144.0 COG3153@1|root,COG3153@2|Bacteria,2GAR3@200795|Chloroflexi,377E4@32061|Chloroflexia 32061|Chloroflexia S PFAM GCN5-related N-acetyltransferase - - - ko:K03824 - - - - ko00000,ko01000 - - - Acetyltransf_9 PJD2_k127_594645_2 926554.KI912636_gene3089 1.408e-61 216.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family yfiT - - - - - - - - - - - DinB_2 PJD2_k127_594645_6 84531.JMTZ01000068_gene1770 4.073e-42 177.0 COG2132@1|root,COG4935@1|root,COG2132@2|Bacteria,COG4935@2|Bacteria,1NJV7@1224|Proteobacteria,1RN7Q@1236|Gammaproteobacteria,1XAU9@135614|Xanthomonadales 135614|Xanthomonadales O Metallo-peptidase family M12B Reprolysin-like - - - - - - - - - - - - Reprolysin_4 PJD2_k127_594645_9 459349.CLOAM0984 2.064e-16 94.0 COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25 PJD2_k127_594645_3 160799.PBOR_31120 4.049e-50 190.0 COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA PJD2_k127_5958300_5 643648.Slip_1424 2.479e-89 298.0 COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42JKS@68298|Syntrophomonadaceae 186801|Clostridia H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - iHN637.CLJU_RS15750 ALAD PJD2_k127_5958300_1 1200792.AKYF01000009_gene3002 2.121e-166 543.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,26QYR@186822|Paenibacillaceae 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS08395 Aminotran_3 PJD2_k127_5958300_10 192952.MM_1036 9.848e-30 126.0 COG1268@1|root,arCOG02986@2157|Archaea,2XWSG@28890|Euryarchaeota,2N9UN@224756|Methanomicrobia 224756|Methanomicrobia S PFAM BioY protein - - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY PJD2_k127_5958300_12 1266925.JHVX01000003_gene500 1.216e-07 63.0 COG3103@1|root,COG3103@2|Bacteria,1NQ5X@1224|Proteobacteria,2WA5G@28216|Betaproteobacteria,372RR@32003|Nitrosomonadales 28216|Betaproteobacteria T PFAM SH3, type 3 - - - - - - - - - - - - SH3_3 PJD2_k127_5958300_7 519989.ECTPHS_07142 1.773e-39 167.0 COG2199@1|root,COG3706@2|Bacteria,1MX83@1224|Proteobacteria,1RMRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,dCache_1 PJD2_k127_5958300_2 204669.Acid345_2966 3.163e-145 473.0 COG2079@1|root,COG2079@2|Bacteria,3Y5N1@57723|Acidobacteria,2JK64@204432|Acidobacteriia 204432|Acidobacteriia S MmgE/PrpD family - - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD PJD2_k127_5958300_0 204669.Acid345_3507 3.236e-302 948.0 COG0567@1|root,COG0567@2|Bacteria,3Y3EF@57723|Acidobacteria,2JICX@204432|Acidobacteriia 204432|Acidobacteriia C 2-oxoglutarate dehydrogenase, E1 - - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,OxoGdeHyase_C,Transket_pyr PJD2_k127_5958300_6 1121468.AUBR01000010_gene2459 1.09e-64 248.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,42F1K@68295|Thermoanaerobacterales 186801|Clostridia H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase PJD2_k127_5958300_11 547144.HydHO_0434 1.238e-14 88.0 COG0066@1|root,COG0066@2|Bacteria,2G405@200783|Aquificae 200783|Aquificae E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C PJD2_k127_5958300_3 1382306.JNIM01000001_gene1917 7.1e-137 452.0 COG1032@1|root,COG1032@2|Bacteria,2G7MA@200795|Chloroflexi 200795|Chloroflexi C Radical SAM domain protein - - - - - - - - - - - - B12-binding,Radical_SAM PJD2_k127_5958300_9 886293.Sinac_7277 2.231e-35 144.0 COG0694@1|root,COG0694@2|Bacteria 2|Bacteria O iron-sulfur cluster assembly nfuA - - ko:K07400 - - - - ko00000 - - - Nfu_N,NifU PJD2_k127_5958300_4 326427.Cagg_2251 1.512e-97 333.0 COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi,377MJ@32061|Chloroflexia 32061|Chloroflexia F ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp - - - - - - - - - - - - ATP-grasp_4 PJD2_k127_5958300_8 1047013.AQSP01000099_gene1508 7.741e-38 160.0 COG4907@1|root,COG4907@2|Bacteria,2NR5D@2323|unclassified Bacteria 2|Bacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 PJD2_k127_6015598_5 555500.I215_14913 4.583e-35 140.0 COG0702@1|root,COG0702@2|Bacteria,4NGMK@976|Bacteroidetes,1I2Y0@117743|Flavobacteriia 976|Bacteroidetes GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA PJD2_k127_6015598_0 386456.JQKN01000004_gene217 1.079e-149 497.0 COG1950@1|root,arCOG09731@2157|Archaea,2Y2F9@28890|Euryarchaeota,23PAN@183925|Methanobacteria 183925|Methanobacteria S Mycobacterial 4 TMS phage holin, superfamily IV - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2,Phosphodiest PJD2_k127_6015598_2 926550.CLDAP_40500 9.427e-82 280.0 COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi 2|Bacteria S Belongs to the UPF0173 family - - - - - - - - - - - - Lactamase_B_2 PJD2_k127_6015598_6 1479235.KK366039_gene2850 1.324e-18 95.0 COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,1SCF7@1236|Gammaproteobacteria,1XM1J@135619|Oceanospirillales 135619|Oceanospirillales S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin PJD2_k127_6015598_1 518766.Rmar_1609 2.212e-95 323.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria 2|Bacteria L Protein of unknown function (DUF1722) ybgA - - - - - - - - - - - DUF1722,DUF523 PJD2_k127_6015598_4 452637.Oter_1109 1.621e-49 182.0 COG4276@1|root,COG4276@2|Bacteria,46X6Q@74201|Verrucomicrobia,3K9Y1@414999|Opitutae 414999|Opitutae S Pfam Polyketide cyclase dehydrase and lipid transport - - - - - - - - - - - - - PJD2_k127_6015598_3 751994.AGIG01000028_gene2025 2.103e-60 220.0 COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria 1224|Proteobacteria K PFAM regulatory protein, MerR - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 PJD2_k127_6016406_0 459349.CLOAM0569 0.0 1015.0 COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria 2|Bacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 PJD2_k127_6016406_7 1210884.HG799466_gene12847 1.962e-96 325.0 COG0005@1|root,COG0005@2|Bacteria,2IX9R@203682|Planctomycetes 203682|Planctomycetes F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate - - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 PJD2_k127_6016406_15 290397.Adeh_1311 3.013e-22 108.0 COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WS27@28221|Deltaproteobacteria 28221|Deltaproteobacteria D PFAM DivIVA family protein - - - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA PJD2_k127_6016406_12 645512.GCWU000246_01143 6.313e-56 203.0 COG0325@1|root,COG0325@2|Bacteria,3TB2D@508458|Synergistetes 508458|Synergistetes S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N PJD2_k127_6016406_1 1123242.JH636435_gene2200 7.169e-316 992.0 COG0209@1|root,COG0209@2|Bacteria,2IWU1@203682|Planctomycetes 203682|Planctomycetes F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN PJD2_k127_6016406_4 1306947.ARQD01000005_gene53 1.726e-159 508.0 COG0208@1|root,COG0208@2|Bacteria,2NQ0T@2323|unclassified Bacteria 2|Bacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iJN746.PP_1177 Ribonuc_red_sm PJD2_k127_6016406_16 237727.NAP1_12908 9.941e-08 63.0 COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TSFP@28211|Alphaproteobacteria,2K0P0@204457|Sphingomonadales 204457|Sphingomonadales S Virulence factor BrkB - - - ko:K07058 - - - - ko00000 - - - HAD_2,Virul_fac_BrkB PJD2_k127_6016406_13 309807.SRU_1454 1.901e-36 162.0 COG2374@1|root,COG2374@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Endonuclease_1,Exo_endo_phos,LTD PJD2_k127_6016406_3 765420.OSCT_2114 1.412e-167 580.0 COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia 32061|Chloroflexia Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS PJD2_k127_6016406_14 459349.CLOAM0984 3.184e-23 104.0 COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria 2|Bacteria M Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25 PJD2_k127_6016406_5 1173025.GEI7407_0032 6.833e-151 488.0 COG1252@1|root,COG1252@2|Bacteria,1G20T@1117|Cyanobacteria,1H80B@1150|Oscillatoriales 1117|Cyanobacteria C NADH dehydrogenase, FAD-containing subunit ndbA - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 PJD2_k127_6016406_10 1283300.ATXB01000001_gene988 3.72e-76 266.0 COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1XEHN@135618|Methylococcales 135618|Methylococcales G Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_6,Hydrolase_like PJD2_k127_6016406_9 933262.AXAM01000033_gene1627 6.299e-92 313.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MJGP@213118|Desulfobacterales 28221|Deltaproteobacteria BQ PFAM Histone deacetylase - - - - - - - - - - - - Hist_deacetyl PJD2_k127_6016406_2 583355.Caka_1066 5.029e-304 946.0 COG0365@1|root,COG0365@2|Bacteria,46SBX@74201|Verrucomicrobia,3K77V@414999|Opitutae 414999|Opitutae H Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C PJD2_k127_6016406_6 909663.KI867150_gene490 3.747e-138 452.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MQ4E@213462|Syntrophobacterales 28221|Deltaproteobacteria S Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 PJD2_k127_6016406_11 309801.trd_A0007 8.129e-64 224.0 COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,27Y9H@189775|Thermomicrobia 189775|Thermomicrobia H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) - - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx PJD2_k127_6016406_8 756272.Plabr_2883 2.491e-94 318.0 COG0515@1|root,COG0515@2|Bacteria,2J2D5@203682|Planctomycetes 203682|Planctomycetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase PJD2_k127_6051413_3 1379698.RBG1_1C00001G0608 2.311e-143 479.0 COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N PJD2_k127_6051413_5 502025.Hoch_5710 4.862e-113 385.0 COG0490@1|root,COG1226@1|root,COG4651@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,2YX01@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.2 - - Na_H_Exchanger,TrkA_C,TrkA_N PJD2_k127_6051413_8 1379698.RBG1_1C00001G1677 8.992e-108 360.0 COG3239@1|root,COG3239@2|Bacteria,2NNTZ@2323|unclassified Bacteria 2|Bacteria I Fatty acid desaturase des - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase PJD2_k127_6051413_20 404380.Gbem_1114 1.164e-09 72.0 COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 PJD2_k127_6051413_10 945713.IALB_1675 2.742e-105 357.0 COG1109@1|root,COG1109@2|Bacteria 2|Bacteria G phosphoglucosamine mutase activity glmM - 5.4.2.10,5.4.2.2,5.4.2.8 ko:K01840,ko:K03431,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R02060,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV PJD2_k127_6051413_0 1379698.RBG1_1C00001G0688 3.42e-261 816.0 COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria 2|Bacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iAF987.Gmet_1487 GATase_6,SIS PJD2_k127_6051413_15 1128421.JAGA01000002_gene275 3.418e-43 160.0 COG0251@1|root,COG0251@2|Bacteria,2NPSA@2323|unclassified Bacteria 2|Bacteria J Endoribonuclease L-PSP rutC GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.99.10 ko:K09021,ko:K09022 ko00240,ko01100,map00240,map01100 - R09982,R11098,R11099 RC02768,RC03275,RC03354 ko00000,ko00001,ko01000 - - - Ribonuc_L-PSP PJD2_k127_6051413_21 331678.Cphamn1_2085 5.907e-05 53.0 28PR3@1|root,303J8@2|Bacteria,1FFJ0@1090|Chlorobi 1090|Chlorobi - - - - - - - - - - - - - - - PJD2_k127_6051413_1 290512.Paes_1569 8.261e-253 792.0 COG0481@1|root,COG0481@2|Bacteria,1FDSU@1090|Chlorobi 1090|Chlorobi J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C PJD2_k127_6051413_12 1379698.RBG1_1C00001G0425 2.863e-62 223.0 COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria 2|Bacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 PJD2_k127_6051413_13 1519439.JPJG01000058_gene2064 2.668e-57 213.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,2N6V9@216572|Oscillospiraceae 186801|Clostridia H HemN C-terminal domain hemN - - - - - - - - - - - HemN_C,Radical_SAM PJD2_k127_6051413_14 379066.GAU_1899 6.145e-49 188.0 COG1420@1|root,COG1420@2|Bacteria,1ZTER@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA PJD2_k127_6051413_17 706434.HMPREF9429_00687 5.531e-25 114.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4H5E5@909932|Negativicutes 909932|Negativicutes O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE PJD2_k127_6051413_2 1379698.RBG1_1C00001G1489 3.343e-241 760.0 COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria 2|Bacteria O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 PJD2_k127_6051413_7 517418.Ctha_1824 9.866e-110 370.0 COG0484@1|root,COG0484@2|Bacteria,1FD9R@1090|Chlorobi 1090|Chlorobi J ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG PJD2_k127_6051413_18 526227.Mesil_1997 2.43e-21 103.0 COG1385@1|root,COG1385@2|Bacteria,1WJE1@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA PJD2_k127_6051413_16 868864.Dester_0796 3.268e-27 121.0 COG1610@1|root,COG1610@2|Bacteria,2G4V2@200783|Aquificae 200783|Aquificae S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY PJD2_k127_6051413_19 177437.HRM2_35760 1.066e-09 67.0 COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MKBI@213118|Desulfobacterales 28221|Deltaproteobacteria S Colicin V production protein - - - ko:K03558 - - - - ko00000 - - - Colicin_V PJD2_k127_6051413_6 518766.Rmar_0730 5.395e-112 397.0 COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1FIM7@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr PJD2_k127_6051413_9 518766.Rmar_0977 2.125e-106 366.0 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1FJ4P@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 PJD2_k127_6051413_4 398767.Glov_1013 1.91e-125 422.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 PJD2_k127_6051413_22 509191.AEDB02000003_gene1019 0.0006314 45.0 2DPV4@1|root,333HA@2|Bacteria,1VH7Z@1239|Firmicutes,24SC2@186801|Clostridia,3WQ8C@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - PJD2_k127_6051413_11 1047013.AQSP01000105_gene1443 6.025e-91 317.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria 2|Bacteria M Tricorn protease C1 domain - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ PJD2_k127_6059547_4 1267534.KB906759_gene1791 9.415e-75 259.0 2CEY7@1|root,2Z8CG@2|Bacteria 2|Bacteria S membrane - - - - - - - - - - - - - PJD2_k127_6059547_0 1267534.KB906759_gene1792 1.35e-240 756.0 COG1053@1|root,COG1053@2|Bacteria 2|Bacteria C succinate dehydrogenase sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C PJD2_k127_6059547_3 1379698.RBG1_1C00001G0452 5.621e-97 330.0 COG0479@1|root,COG0479@2|Bacteria,2NPY8@2323|unclassified Bacteria 2|Bacteria C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein sdhB1 - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0247c Fer2_3,Fer4_8 PJD2_k127_6059547_5 880073.Calab_1912 4e-74 257.0 COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT PJD2_k127_6059547_9 290397.Adeh_4094 7.15e-51 198.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2Z0PZ@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF PJD2_k127_6059547_8 883126.HMPREF9710_02810 4.841e-56 210.0 COG0438@1|root,COG0438@2|Bacteria,1RCC7@1224|Proteobacteria,2W6IC@28216|Betaproteobacteria 28216|Betaproteobacteria M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - - PJD2_k127_6059547_10 314230.DSM3645_19268 7.357e-46 181.0 COG0438@1|root,COG0438@2|Bacteria,2IY70@203682|Planctomycetes 203682|Planctomycetes M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 PJD2_k127_6059547_6 485913.Krac_8056 4.598e-65 239.0 COG0726@1|root,COG0726@2|Bacteria,2G8HZ@200795|Chloroflexi 200795|Chloroflexi G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 PJD2_k127_6059547_7 525904.Tter_2798 3.93e-58 220.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups epsD GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K00754,ko:K19422 - - - - ko00000,ko01000 - GT4 - Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_6059547_11 525904.Tter_2794 1.941e-32 146.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_6059547_2 237368.SCABRO_03724 1.57e-172 561.0 COG1389@1|root,COG1389@2|Bacteria,2J2A8@203682|Planctomycetes 203682|Planctomycetes L Relaxes both positive and negative superturns and exhibits a strong decatenase activity top6B - 5.99.1.3 ko:K03167 - - - - ko00000,ko01000,ko03032 - - - HATPase_c,Topo-VIb_trans PJD2_k127_6059547_1 237368.SCABRO_03725 8.315e-176 588.0 COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes 203682|Planctomycetes L Relaxes both positive and negative superturns and exhibits a strong decatenase activity top6A - 5.99.1.3 ko:K03166 - - - - ko00000,ko01000,ko03032 - - - TP6A_N PJD2_k127_6059547_12 1384056.N787_10035 1.705e-18 93.0 COG1476@1|root,COG1476@2|Bacteria,1N7BB@1224|Proteobacteria,1SCG8@1236|Gammaproteobacteria,1X8D5@135614|Xanthomonadales 135614|Xanthomonadales K Helix-turn-helix domain - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 PJD2_k127_6067514_2 1121374.KB891586_gene2742 1.003e-95 318.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RRS7@1236|Gammaproteobacteria 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - RimK,TrkA_C PJD2_k127_6067514_7 382464.ABSI01000010_gene3267 2.14e-28 120.0 COG4067@1|root,COG4067@2|Bacteria,46XTD@74201|Verrucomicrobia,2IWIG@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease PJD2_k127_6067514_8 525373.HMPREF0766_10246 6.686e-28 118.0 COG2259@1|root,COG2259@2|Bacteria,4NTM8@976|Bacteroidetes,1ITB2@117747|Sphingobacteriia 976|Bacteroidetes S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX PJD2_k127_6067514_1 857293.CAAU_2006 1.104e-139 472.0 COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,36E8E@31979|Clostridiaceae 186801|Clostridia C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding PJD2_k127_6067514_5 1198114.AciX9_0126 1.712e-55 211.0 COG0437@1|root,COG3302@1|root,COG0437@2|Bacteria,COG3302@2|Bacteria,3Y5RE@57723|Acidobacteria,2JKSV@204432|Acidobacteriia 204432|Acidobacteriia C 4Fe-4S dicluster domain - - - - - - - - - - - - DmsC,Fer4_11 PJD2_k127_6067514_0 1244869.H261_06576 6.642e-192 617.0 COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,2JRZP@204441|Rhodospirillales 204441|Rhodospirillales C B12 binding domain - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM PJD2_k127_6067514_6 397945.Aave_4620 3.449e-47 180.0 COG4106@1|root,COG4106@2|Bacteria,1QZC8@1224|Proteobacteria,2WHJN@28216|Betaproteobacteria,4AJYU@80864|Comamonadaceae 28216|Betaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 PJD2_k127_6067514_4 1408473.JHXO01000001_gene1949 6.002e-57 217.0 COG3104@1|root,COG3104@2|Bacteria,4NIIT@976|Bacteroidetes,2FR16@200643|Bacteroidia 976|Bacteroidetes E Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 PJD2_k127_6067514_3 1047013.AQSP01000061_gene1215 1.025e-89 306.0 COG1028@1|root,COG1028@2|Bacteria,2NRAR@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 PJD2_k127_6067514_11 1120998.AUFC01000036_gene1283 2.99e-05 48.0 2EHTG@1|root,33BJ4@2|Bacteria 2|Bacteria S Flp Fap pilin component - - - - - - - - - - - - Flp_Fap PJD2_k127_6067514_10 880072.Desac_0791 4.958e-07 55.0 COG4960@1|root,COG4960@2|Bacteria,1N7J0@1224|Proteobacteria 1224|Proteobacteria OU Peptidase A24A, prepilin type IV cpaA1 - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 PJD2_k127_6093614_13 1123073.KB899241_gene3242 1.702e-28 132.0 COG1572@1|root,COG3210@1|root,COG3391@1|root,COG4932@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria,1SUAH@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Parallel beta-helix repeats - - - - - - - - - - - - - PJD2_k127_6093614_14 613026.HRAG_02000 1.135e-26 119.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2YP47@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N PJD2_k127_6093614_3 1238182.C882_0817 6.712e-134 438.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2JQDT@204441|Rhodospirillales 204441|Rhodospirillales JKL Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C PJD2_k127_6093614_12 1127673.GLIP_4008 2.017e-29 138.0 COG4928@1|root,COG4928@2|Bacteria,1MWRP@1224|Proteobacteria,1RQK1@1236|Gammaproteobacteria,46BZB@72275|Alteromonadaceae 1236|Gammaproteobacteria S KAP family P-loop domain - - - - - - - - - - - - KAP_NTPase PJD2_k127_6093614_5 85643.Tmz1t_2954 4.603e-111 370.0 COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,2VP5E@28216|Betaproteobacteria,2KVHQ@206389|Rhodocyclales 28216|Betaproteobacteria C Zinc-binding dehydrogenase - - 1.1.1.368 ko:K07538 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05581 RC00850 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N PJD2_k127_6093614_4 1187851.A33M_3194 6.715e-131 439.0 COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - 3.7.1.21 ko:K07539 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05593,R05594,R10696 RC01430,RC01431,RC03237 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 PJD2_k127_6093614_10 706587.Desti_1480 1.22e-51 196.0 COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase bamR - 4.2.1.100 ko:K07537 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05597 RC03168 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 PJD2_k127_6093614_15 1379698.RBG1_1C00001G0893 7.926e-22 105.0 COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria 2|Bacteria K Bacterial regulatory proteins, tetR family - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_4,TetR_N PJD2_k127_6093614_1 85643.Tmz1t_2951 8.271e-144 467.0 COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales 206389|Rhodocyclales E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04112 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D PJD2_k127_6093614_0 85643.Tmz1t_2950 1.87e-186 607.0 COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2W3EH@28216|Betaproteobacteria,2KZ1E@206389|Rhodocyclales 206389|Rhodocyclales E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04113 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D PJD2_k127_6093614_2 648757.Rvan_0039 4.216e-137 467.0 COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Benzoyl-CoA reductase subunit - - 1.3.7.8 ko:K04114 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG PJD2_k127_6093614_7 316056.RPC_1026 7.392e-87 295.0 COG1924@1|root,COG1924@2|Bacteria,1MY0N@1224|Proteobacteria,2U4V9@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Benzoyl-CoA reductase subunit - - 1.3.7.8 ko:K04115 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG PJD2_k127_6093614_8 1121918.ARWE01000001_gene3598 6.006e-81 278.0 COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria 1224|Proteobacteria IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 PJD2_k127_6093614_16 649638.Trad_1754 1.392e-07 59.0 COG4914@1|root,COG4914@2|Bacteria,1WNGG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - PJD2_k127_6093614_9 1047013.AQSP01000052_gene2599 1.244e-73 265.0 COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria 2|Bacteria CP ABC-2 family transporter protein natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 PJD2_k127_6093614_6 1047013.AQSP01000052_gene2600 1.554e-101 339.0 COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4162) natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 PJD2_k127_6093614_11 1307759.JOMJ01000003_gene2150 4.142e-49 184.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MB1P@213115|Desulfovibrionales 28221|Deltaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - iAF987.Gmet_1875 Ham1p_like PJD2_k127_610125_8 386043.lwe2734 9.027e-38 151.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,26IR6@186820|Listeriaceae 91061|Bacilli D Sporulation initiation inhibitor soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 PJD2_k127_610125_7 682795.AciX8_4480 1.553e-41 171.0 292YA@1|root,2ZQFS@2|Bacteria,3Y4KM@57723|Acidobacteria,2JJD7@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - PJD2_k127_610125_2 391937.NA2_08766 2.165e-143 459.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,43NHA@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Belongs to the pirin family yhhW - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C PJD2_k127_610125_9 1096769.Pelub83DRAFT_0415 5.007e-19 91.0 2FDFA@1|root,345GY@2|Bacteria,1P1RR@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - PJD2_k127_610125_3 926550.CLDAP_22570 2.293e-136 449.0 COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi 200795|Chloroflexi K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_RNA_bind PJD2_k127_610125_10 84531.JMTZ01000030_gene140 8.676e-16 81.0 2EGSV@1|root,33AIZ@2|Bacteria,1NGPG@1224|Proteobacteria,1SGM3@1236|Gammaproteobacteria,1X8YC@135614|Xanthomonadales 135614|Xanthomonadales S Cysteine-rich CPXCG - - - - - - - - - - - - Cys_rich_CPXG PJD2_k127_610125_5 929703.KE386491_gene3448 1.432e-76 278.0 COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,47JA4@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307,ko:K14387 ko04725,ko05231,map04725,map05231 - - - ko00000,ko00001,ko02000 2.A.21,2.A.21.8 - - HD_4,SSF PJD2_k127_610125_0 1267533.KB906736_gene1246 4.437e-217 705.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia 204432|Acidobacteriia KLTU Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase PJD2_k127_610125_6 234267.Acid_5749 1.229e-56 221.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 PJD2_k127_610125_4 234267.Acid_3938 2.596e-81 277.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 PJD2_k127_610125_1 234267.Acid_4431 7.074e-156 526.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 PJD2_k127_6133119_26 1356852.N008_19465 1.065e-07 54.0 COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47YFC@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 PJD2_k127_6133119_8 489825.LYNGBM3L_01100 1.055e-64 231.0 COG0398@1|root,COG0398@2|Bacteria,1G3R9@1117|Cyanobacteria,1H8VH@1150|Oscillatoriales 1117|Cyanobacteria S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 PJD2_k127_6133119_7 925409.KI911562_gene2506 2.314e-67 238.0 COG0518@1|root,COG0518@2|Bacteria,4NMFC@976|Bacteroidetes,1ISTT@117747|Sphingobacteriia 976|Bacteroidetes F glutamine amidotransferase - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase PJD2_k127_6133119_6 1123278.KB893562_gene3248 1.949e-73 262.0 COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,47K2Q@768503|Cytophagia 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3 PJD2_k127_6133119_9 670487.Ocepr_0305 1.251e-61 220.0 COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran PJD2_k127_6133119_16 373903.Hore_14670 1.374e-24 117.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,3WBTU@53433|Halanaerobiales 186801|Clostridia T Low molecular weight phosphatase family arsC - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc PJD2_k127_6133119_0 1379698.RBG1_1C00001G0509 2.244e-200 649.0 COG1042@1|root,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria 2|Bacteria C synthetase (ADP forming), alpha - - 6.2.1.13 ko:K01905,ko:K09181,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig PJD2_k127_6133119_11 1121920.AUAU01000006_gene301 8.434e-49 182.0 2BYAB@1|root,32R2Z@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_6133119_21 394221.Mmar10_1379 1.94e-14 80.0 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4440,SnoaL_2,SnoaL_3 PJD2_k127_6133119_28 1163407.UU7_13448 4.268e-06 58.0 COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,1S2I3@1236|Gammaproteobacteria,1X6BV@135614|Xanthomonadales 135614|Xanthomonadales S integral membrane protein - - - - - - - - - - - - DUF1211 PJD2_k127_6133119_2 448385.sce0669 2.197e-97 336.0 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria,2YUM5@29|Myxococcales 28221|Deltaproteobacteria E Sarcosine oxidase soxB - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO,Fer2_BFD PJD2_k127_6133119_20 1254432.SCE1572_46595 1.364e-14 78.0 COG0665@1|root,COG0665@2|Bacteria,1QAP8@1224|Proteobacteria,4357F@68525|delta/epsilon subdivisions,2X96I@28221|Deltaproteobacteria,2Z27U@29|Myxococcales 28221|Deltaproteobacteria E BFD-like [2Fe-2S] binding domain - - - - - - - - - - - - Fer2_BFD PJD2_k127_6133119_15 1082933.MEA186_32038 5.055e-39 165.0 COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family - - 1.5.3.1,1.5.99.5 ko:K00302,ko:K22086 ko00260,ko00680,ko01100,ko01120,map00260,map00680,map01100,map01120 - R00609,R00610 RC00060,RC00190,RC00557 ko00000,ko00001,ko01000 - - - FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2 PJD2_k127_6133119_3 517418.Ctha_2620 3.949e-97 335.0 COG0612@1|root,COG0612@2|Bacteria 2|Bacteria L Peptidase, M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_6133119_4 926562.Oweho_1655 1.319e-84 306.0 COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1HWQI@117743|Flavobacteriia,2PA72@246874|Cryomorphaceae 976|Bacteroidetes S Peptidase M16 inactive domain - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_6133119_12 756272.Plabr_4381 5.328e-48 180.0 COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes 203682|Planctomycetes F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran PJD2_k127_6133119_13 439235.Dalk_1881 5.203e-44 183.0 COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Tetratricopeptide repeat - - - - - - - - - - - - PMT_2 PJD2_k127_6133119_25 1038860.AXAP01000051_gene5410 2.414e-08 67.0 COG0457@1|root,COG0457@2|Bacteria,1QW7M@1224|Proteobacteria,2U1I6@28211|Alphaproteobacteria,3JS3H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U TPR repeat - - - - - - - - - - - - Asp_protease_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 PJD2_k127_6133119_18 459349.CLOAM0602 9.135e-18 98.0 COG4412@1|root,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - 3.4.17.22 ko:K07752 - - - - ko00000,ko01000,ko01002 - - - Cellulase,DUF4859,F5_F8_type_C,FlgD_ig PJD2_k127_6133119_17 1407650.BAUB01000006_gene1432 1.606e-22 113.0 COG2133@1|root,COG2133@2|Bacteria,1GP2C@1117|Cyanobacteria,1H24N@1129|Synechococcus 1117|Cyanobacteria G pyrroloquinoline quinone binding - - - - - - - - - - - - - PJD2_k127_6133119_19 869210.Marky_0902 4.894e-17 95.0 COG1621@1|root,COG1621@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32N PJD2_k127_6133119_10 420324.KI911943_gene5344 3.633e-60 222.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,2TTFW@28211|Alphaproteobacteria,1JQV8@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM CBS domain containing protein - - - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - CBS,Peptidase_M50 PJD2_k127_6133119_22 243231.GSU1057 1.575e-12 76.0 COG0457@1|root,COG0457@2|Bacteria,1P22J@1224|Proteobacteria,4310H@68525|delta/epsilon subdivisions,2WWBW@28221|Deltaproteobacteria,43VHQ@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - PJD2_k127_6133119_24 1004149.AFOE01000050_gene2594 4.663e-09 68.0 COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,1HX8F@117743|Flavobacteriia 976|Bacteroidetes NU tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8 PJD2_k127_6133119_29 402880.MmarC5_1652 1.898e-05 52.0 COG2314@1|root,arCOG03293@2157|Archaea,2XYU1@28890|Euryarchaeota,23RS2@183939|Methanococci 183939|Methanococci S Predicted membrane protein (DUF2085) - - - - - - - - - - - - - PJD2_k127_6133119_5 1450694.BTS2_4029 6.582e-78 271.0 COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZC28@1386|Bacillus 91061|Bacilli G fructose-1,6-bisphosphatase glpX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX PJD2_k127_6133119_1 671143.DAMO_2552 2.554e-138 453.0 COG2256@1|root,COG2256@2|Bacteria,2NNTG@2323|unclassified Bacteria 2|Bacteria L MgsA AAA+ ATPase C terminal rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N PJD2_k127_6133119_23 258052.JNYV01000004_gene4386 2.407e-09 71.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,2M1D1@2063|Kitasatospora 201174|Actinobacteria L PD-(D/E)XK nuclease superfamily uvrD3 - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C PJD2_k127_6133119_27 694427.Palpr_0523 2.614e-07 64.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,4NFZQ@976|Bacteroidetes,2FN03@200643|Bacteroidia,22W74@171551|Porphyromonadaceae 976|Bacteroidetes L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1 PJD2_k127_6133119_14 290397.Adeh_0097 1.461e-43 172.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YU2G@29|Myxococcales 28221|Deltaproteobacteria L DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C PJD2_k127_6133857_0 269799.Gmet_1393 8.552e-64 226.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales 28221|Deltaproteobacteria NU General secretory system II, protein E domain protein pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N,cNMP_binding PJD2_k127_6133857_3 1234595.C725_2704 0.0007223 53.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria 28211|Alphaproteobacteria H receptor - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec PJD2_k127_6133857_2 1246484.D479_15557 4.459e-07 59.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli,3NF0U@45667|Halobacillus 91061|Bacilli S ECF-type riboflavin transporter, S component - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt PJD2_k127_6133857_1 1379698.RBG1_1C00001G1245 6.669e-28 132.0 COG1629@1|root,COG4771@2|Bacteria,2NRGW@2323|unclassified Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarboxypepD_reg,TonB_dep_Rec PJD2_k127_6139757_3 517418.Ctha_2374 4.112e-26 118.0 COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - 3.4.21.62 ko:K01342,ko:K06894,ko:K12287,ko:K20276 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko02044,ko03110 - - - FG-GAP,VCBS PJD2_k127_6139757_4 247490.KSU1_C0449 7.932e-24 107.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - Cadherin_3,DUF4347,Peptidase_S8 PJD2_k127_6139757_2 1121937.AUHJ01000015_gene111 6.149e-44 165.0 COG1764@1|root,COG1764@2|Bacteria,1RJIP@1224|Proteobacteria,1S6QM@1236|Gammaproteobacteria 1236|Gammaproteobacteria O redox protein regulator of disulfide bond formation - - - - - - - - - - - - OsmC PJD2_k127_6139757_5 459349.CLOAM1790 1.092e-10 75.0 COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria 2|Bacteria K Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS PJD2_k127_6139757_1 246194.CHY_0339 1.397e-52 194.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,42FJD@68295|Thermoanaerobacterales 186801|Clostridia K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N PJD2_k127_6139757_0 1379698.RBG1_1C00001G0278 2.564e-303 947.0 COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria 2|Bacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV PJD2_k127_6167082_16 237368.SCABRO_00307 8.305e-07 58.0 COG0260@1|root,COG0260@2|Bacteria,2IY4Q@203682|Planctomycetes 203682|Planctomycetes E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N PJD2_k127_6167082_14 697281.Mahau_0044 9.99e-27 115.0 COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales 186801|Clostridia T PFAM Protein-tyrosine phosphatase, low molecular weight ywlE - 3.1.3.48,3.9.1.2 ko:K01104,ko:K20201 - - - - ko00000,ko01000 - - - LMWPc PJD2_k127_6167082_12 1158345.JNLL01000001_gene759 2.629e-42 160.0 COG0698@1|root,COG0698@2|Bacteria,2G43P@200783|Aquificae 200783|Aquificae G ribose 5-phosphate isomerase B rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB PJD2_k127_6167082_1 986075.CathTA2_2820 1.668e-169 550.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT PJD2_k127_6167082_9 1280692.AUJL01000006_gene1531 1.091e-54 196.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,36HY1@31979|Clostridiaceae 186801|Clostridia K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone PJD2_k127_6167082_10 648996.Theam_0438 5.9e-45 172.0 COG0805@1|root,COG0805@2|Bacteria,2G41B@200783|Aquificae 200783|Aquificae U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC PJD2_k127_6167082_13 517418.Ctha_0064 1.137e-29 123.0 COG0799@1|root,COG0799@2|Bacteria,1FE3F@1090|Chlorobi 1090|Chlorobi J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS PJD2_k127_6167082_2 584708.Apau_1036 2.816e-131 439.0 COG0018@1|root,COG0018@2|Bacteria,3TA5K@508458|Synergistetes 508458|Synergistetes J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d PJD2_k127_6167082_5 483219.LILAB_26775 1.593e-90 315.0 COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales 28221|Deltaproteobacteria G pfkB family carbohydrate kinase - - - - - - - - - - - iAF987.Gmet_2683 PfkB PJD2_k127_6167082_15 555088.DealDRAFT_1142 3.597e-22 106.0 2C0MY@1|root,2ZC2Z@2|Bacteria,1V9XB@1239|Firmicutes,24PCF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - PJD2_k127_6167082_7 635013.TherJR_2774 2.648e-78 278.0 COG3437@1|root,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,267DF@186807|Peptococcaceae 186801|Clostridia KT HD domain - - - ko:K07814 - - - - ko00000,ko02022 - - - GGDEF,HD,Hpt,Response_reg PJD2_k127_6167082_3 1379698.RBG1_1C00001G0378 7.215e-108 359.0 COG0150@1|root,COG0150@2|Bacteria,2NNUJ@2323|unclassified Bacteria 2|Bacteria F AIR synthase related protein, N-terminal domain purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 ko:K01933,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1844,iECSF_1327.ECSF_2340 AIRS,AIRS_C PJD2_k127_6167082_17 1183438.GKIL_0461 1.096e-06 61.0 COG1749@1|root,COG3386@1|root,COG3391@1|root,COG3525@1|root,COG5492@1|root,COG1749@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,COG3525@2|Bacteria,COG5492@2|Bacteria,1G2ZW@1117|Cyanobacteria 1117|Cyanobacteria N Ig domain protein group 1 domain protein - - - - - - - - - - - - Big_1,DUF4082 PJD2_k127_6167082_11 572479.Hprae_0490 1.327e-42 162.0 COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3WAPY@53433|Halanaerobiales 186801|Clostridia S TIGRFAM DJ-1 family protein - - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI PJD2_k127_6167082_6 448385.sce2668 5.953e-86 306.0 COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria 1224|Proteobacteria K PFAM sigma-54 factor interaction domain-containing protein - - - - - - - - - - - - GAF_2,HTH_8,Sigma54_activat PJD2_k127_6167082_8 1121918.ARWE01000001_gene2973 7.339e-59 218.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,43S3G@69541|Desulfuromonadales 28221|Deltaproteobacteria S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 PJD2_k127_6167082_4 1211814.CAPG01000070_gene3300 7.945e-104 354.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF PJD2_k127_6167082_0 338963.Pcar_2001 5.32e-229 727.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,43SBR@69541|Desulfuromonadales 28221|Deltaproteobacteria C Inorganic H+ pyrophosphatase hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase PJD2_k127_6171162_7 1125863.JAFN01000001_gene2144 3.723e-92 323.0 COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria 28221|Deltaproteobacteria N transport system involved in gliding motility, auxiliary - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC_transp_aux PJD2_k127_6171162_21 1173029.JH980292_gene1922 2.966e-05 56.0 COG3170@1|root,COG3170@2|Bacteria,1G6DU@1117|Cyanobacteria,1HB94@1150|Oscillatoriales 1117|Cyanobacteria NU Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 PJD2_k127_6171162_11 945713.IALB_2615 4.535e-58 214.0 COG1355@1|root,COG1355@2|Bacteria 2|Bacteria C regulation of microtubule-based process - - - ko:K06990 - - - - ko00000,ko04812 - - - AMMECR1,Memo PJD2_k127_6171162_14 1123371.ATXH01000018_gene1391 6.079e-44 173.0 COG2078@1|root,COG2078@2|Bacteria,2GH4V@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S AMMECR1 - - - ko:K09141 - - - - ko00000 - - - AMMECR1 PJD2_k127_6171162_1 575540.Isop_2730 6.086e-196 623.0 COG2719@1|root,COG2719@2|Bacteria,2IXSH@203682|Planctomycetes 203682|Planctomycetes S PFAM SpoVR like protein - - - ko:K06415 - - - - ko00000 - - - SpoVR PJD2_k127_6171162_3 1128421.JAGA01000002_gene89 1.36e-150 484.0 COG2718@1|root,COG2718@2|Bacteria 2|Bacteria S Protein of unknown function (DUF444) yhbH - - ko:K09786 - - - - ko00000 - - - DUF444,Haem_oxygenas_2 PJD2_k127_6171162_0 1128421.JAGA01000002_gene90 0.0 1020.0 COG2766@1|root,COG2766@2|Bacteria 2|Bacteria T protein kinase activity prkA GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA PJD2_k127_6171162_17 713586.KB900536_gene189 6.259e-41 158.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales 135613|Chromatiales FG PFAM Histidine triad (HIT) protein - - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT PJD2_k127_6171162_19 886293.Sinac_7075 2.922e-14 79.0 2E5IJ@1|root,3309Y@2|Bacteria,2J0P5@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - PJD2_k127_6171162_5 635013.TherJR_2339 1.753e-116 387.0 COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,25EPJ@186801|Clostridia,261ES@186807|Peptococcaceae 186801|Clostridia M PFAM Glycosyl - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 PJD2_k127_6171162_13 1430331.EP10_07455 6.095e-46 176.0 COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1WF5D@129337|Geobacillus 91061|Bacilli S GlcNAc-PI de-N-acetylase bshB1 - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L PJD2_k127_6171162_18 861299.J421_3229 2.058e-28 132.0 COG4365@1|root,COG4365@2|Bacteria,1ZTG0@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Bacillithiol biosynthesis BshC - - - ko:K22136 - - - - ko00000 - - - BshC PJD2_k127_6171162_15 997346.HMPREF9374_3566 6.09e-43 166.0 COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,27BS9@186824|Thermoactinomycetaceae 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25 PJD2_k127_6171162_2 1232410.KI421413_gene543 1.378e-177 571.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,43T3U@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C PJD2_k127_6171162_16 861450.HMPREF0080_00399 7.146e-42 168.0 COG1663@1|root,COG1663@2|Bacteria,1TWGA@1239|Firmicutes,4H97G@909932|Negativicutes 909932|Negativicutes M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Glycos_transf_N,LpxK PJD2_k127_6171162_12 1379698.RBG1_1C00001G1645 6.269e-48 186.0 COG2121@1|root,COG2121@2|Bacteria,2NPP6@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF374) MA20_05800 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527,ko:K09778 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - DUF374 PJD2_k127_6171162_9 671143.DAMO_1646 1.71e-75 267.0 COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria 2|Bacteria I Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB PJD2_k127_6171162_10 1379270.AUXF01000006_gene298 3.826e-67 245.0 COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA PJD2_k127_6171162_8 401526.TcarDRAFT_0101 1.161e-81 279.0 COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes 909932|Negativicutes M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep,Hexapep_2 PJD2_k127_6171162_4 1379698.RBG1_1C00001G1649 1.966e-130 432.0 COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria 2|Bacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis fabZ GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 ko:K02372,ko:K02535,ko:K13599,ko:K16363 ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020 M00060,M00083,M00498,M00572 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022 - - - FabA,LpxC PJD2_k127_6171162_6 1379698.RBG1_1C00001G1848 1.371e-103 350.0 COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria 2|Bacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - ic_1306.c0216 Hexapep,Hexapep_2,LpxD PJD2_k127_6171162_20 1379698.RBG1_1C00001G1847 6.143e-07 52.0 COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria 2|Bacteria M Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH PJD2_k127_6187040_16 1896.JOAU01000039_gene509 2.414e-08 62.0 COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria 201174|Actinobacteria GM Nad-dependent epimerase dehydratase - - - - - - - - - - - - DUF2867,NAD_binding_10 PJD2_k127_6187040_11 220664.PFL_5484 9.264e-48 191.0 COG2303@1|root,COG2303@2|Bacteria,1PICJ@1224|Proteobacteria,1RV5E@1236|Gammaproteobacteria,1YTFY@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria C FAD binding domain - - - - - - - - - - - - - PJD2_k127_6187040_13 706587.Desti_2813 3.713e-13 78.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 PJD2_k127_6187040_12 1227457.C451_03609 1.338e-17 94.0 COG0726@1|root,arCOG02876@2157|Archaea,2XWD9@28890|Euryarchaeota,23U0Q@183963|Halobacteria 183963|Halobacteria G xylanase chitin deacetylase - - - - - - - - - - - - DUF3473,Polysacc_deac_1 PJD2_k127_6187040_15 234267.Acid_4636 5.101e-10 69.0 COG2456@1|root,COG2456@2|Bacteria 2|Bacteria M Psort location CytoplasmicMembrane, score - - - ko:K09153 - - - - ko00000 - - - DUF2304 PJD2_k127_6187040_7 234267.Acid_4635 1.65e-69 243.0 COG1216@1|root,COG1216@2|Bacteria,3Y9AS@57723|Acidobacteria 57723|Acidobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 PJD2_k127_6187040_9 981384.AEYW01000022_gene3648 1.94e-55 206.0 COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,2U8QC@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferase family 2 - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 PJD2_k127_6187040_10 1379698.RBG1_1C00001G1318 1.823e-54 204.0 COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria 2|Bacteria S Lysylphosphatidylglycerol synthase TM region mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM PJD2_k127_6187040_6 1047013.AQSP01000142_gene241 8.839e-77 260.0 COG0252@1|root,COG0252@2|Bacteria,2NPMK@2323|unclassified Bacteria 2|Bacteria EJ Asparaginase ansA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase PJD2_k127_6187040_4 1047013.AQSP01000142_gene241 1.515e-130 424.0 COG0252@1|root,COG0252@2|Bacteria,2NPMK@2323|unclassified Bacteria 2|Bacteria EJ Asparaginase ansA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase PJD2_k127_6187040_3 1321778.HMPREF1982_00035 7.324e-147 488.0 COG2511@1|root,COG2511@2|Bacteria,1UPG0@1239|Firmicutes,25HFT@186801|Clostridia 186801|Clostridia J GatB/GatE catalytic domain - - - - - - - - - - - - GatB_N PJD2_k127_6187040_17 761193.Runsl_2077 0.0005003 45.0 COG3637@1|root,COG3637@2|Bacteria,4NMX1@976|Bacteroidetes,47Q6V@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 PJD2_k127_6187040_2 270374.MELB17_14356 1.465e-147 489.0 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria 1236|Gammaproteobacteria O carbamoyl transferase, NodU family - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N PJD2_k127_6187040_8 1484157.PSNIH2_17045 1.547e-56 209.0 COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,1RYP1@1236|Gammaproteobacteria,3VZ2J@53335|Pantoea 1236|Gammaproteobacteria G Lipopolysaccharide biosynthesis protein walW - - - - - - - - - - - - PJD2_k127_6187040_1 1469245.JFBG01000071_gene69 1.514e-155 499.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1WWGS@135613|Chromatiales 135613|Chromatiales E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide - - - - - - - - - - - - Cys_Met_Meta_PP PJD2_k127_6187040_0 933115.GPDM_08165 1.342e-191 608.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26DKN@186818|Planococcaceae 91061|Bacilli C COG1012 NAD-dependent aldehyde dehydrogenases gabD_2 - 1.2.1.9 ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 M00308,M00633 R01058 RC00242 ko00000,ko00001,ko00002,ko01000 - - - Aldedh PJD2_k127_6187040_5 1191523.MROS_0241 1.132e-129 423.0 COG0460@1|root,COG0460@2|Bacteria 2|Bacteria E homoserine dehydrogenase activity hom - 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - Homoserine_dh,NAD_binding_3 PJD2_k127_6191373_1 443143.GM18_3184 1.235e-19 104.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4347,LVIVD PJD2_k127_6191373_0 1210884.HG799465_gene11340 3.784e-87 293.0 COG1801@1|root,COG1801@2|Bacteria,2IYWM@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 PJD2_k127_6195551_6 1211813.CAPH01000007_gene1821 1.133e-18 96.0 COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia,22U2X@171550|Rikenellaceae 976|Bacteroidetes S Oxygen tolerance batD - - - - - - - - - - - BatD,TPR_2 PJD2_k127_6195551_4 1379698.RBG1_1C00001G1772 6.793e-28 127.0 COG0457@1|root,COG0457@2|Bacteria,2NQ3H@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 PJD2_k127_6195551_7 383372.Rcas_2061 4.05e-12 78.0 COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia 32061|Chloroflexia T PFAM Forkhead-associated protein - - - - - - - - - - - - DUF3662,FHA PJD2_k127_6195551_3 1382306.JNIM01000001_gene897 1.865e-58 211.0 COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi 200795|Chloroflexi T SMART protein phosphatase 2C domain protein - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 PJD2_k127_6195551_2 1210884.HG799464_gene11148 1.452e-64 244.0 COG2206@1|root,COG2206@2|Bacteria,2IWTK@203682|Planctomycetes 203682|Planctomycetes T HD domain - - - - - - - - - - - - FHA,GAF_2,HD PJD2_k127_6195551_0 338963.Pcar_1852 5.485e-277 870.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,43SXK@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD PJD2_k127_6195551_5 1121920.AUAU01000005_gene1059 8.639e-28 123.0 2B9NZ@1|root,3231D@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1579) - - - - - - - - - - - - DUF1579 PJD2_k127_6195551_1 401526.TcarDRAFT_1649 2.031e-169 550.0 COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,4H33G@909932|Negativicutes 909932|Negativicutes C Radical SAM domain protein - - - - - - - - - - - - DUF2344,Radical_SAM PJD2_k127_6195551_8 1121468.AUBR01000058_gene880 0.0001958 47.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,42G5U@68295|Thermoanaerobacterales 186801|Clostridia L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS PJD2_k127_6205028_15 880073.Calab_1131 2.27e-17 85.0 COG0457@1|root,COG0457@2|Bacteria 880073.Calab_1131|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - PJD2_k127_6205028_7 880073.Calab_1130 9.213e-94 319.0 COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria 2|Bacteria G Bacterial extracellular solute-binding protein, family 7 - - - ko:K11688,ko:K21395 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP PJD2_k127_6205028_14 1121396.KB893095_gene4378 2.998e-18 94.0 COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,42TZJ@68525|delta/epsilon subdivisions,2WQB8@28221|Deltaproteobacteria,2MKJH@213118|Desulfobacterales 28221|Deltaproteobacteria G PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - - - - - - - - - - DctQ PJD2_k127_6205028_3 1167006.UWK_01424 7.027e-146 482.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MI9P@213118|Desulfobacterales 28221|Deltaproteobacteria G PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM,DctQ PJD2_k127_6205028_13 1293054.HSACCH_02544 3.063e-48 187.0 COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,3WC93@53433|Halanaerobiales 186801|Clostridia M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 PJD2_k127_6205028_17 1123508.JH636442_gene4097 1.353e-13 84.0 28NUF@1|root,33DCF@2|Bacteria,2J1TB@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - PJD2_k127_6205028_5 1379698.RBG1_1C00001G1345 9.11e-123 414.0 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria 2|Bacteria KT COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit rsbU - 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 - - - GAF,GAF_2,HATPase_c_2,SSF,SpoIIE PJD2_k127_6205028_6 1120983.KB894570_gene1663 3.043e-95 325.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,1JN8P@119043|Rhodobiaceae 28211|Alphaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA PJD2_k127_6205028_8 1254432.SCE1572_20525 1.926e-89 325.0 COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales 28221|Deltaproteobacteria S cellulose binding - - - - - - - - - - - - - PJD2_k127_6205028_9 574087.Acear_1851 9.729e-81 304.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,3WAEE@53433|Halanaerobiales 186801|Clostridia V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family nolG - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran PJD2_k127_6205028_2 293826.Amet_0188 3.613e-176 589.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,36F39@31979|Clostridiaceae 186801|Clostridia V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran PJD2_k127_6205028_12 945713.IALB_0694 1.423e-49 194.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 PJD2_k127_6205028_18 1047013.AQSP01000032_gene1975 2.257e-13 82.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - DUF5128,TolB_like PJD2_k127_6205028_16 765869.BDW_08960 2.309e-14 85.0 2AIQT@1|root,3197J@2|Bacteria,1Q1ZE@1224|Proteobacteria,437MA@68525|delta/epsilon subdivisions,2MU3U@213481|Bdellovibrionales,2WYMC@28221|Deltaproteobacteria 213481|Bdellovibrionales - - - - - - - - - - - - - - - PJD2_k127_6205028_10 1499967.BAYZ01000164_gene6670 6.948e-58 209.0 COG3907@1|root,COG3907@2|Bacteria 2|Bacteria S PAP2 superfamily - - - - - - - - - - - - PAP2 PJD2_k127_6205028_1 880073.Calab_1319 2.82e-192 610.0 COG1249@1|root,COG1249@2|Bacteria,2NQMY@2323|unclassified Bacteria 2|Bacteria C Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) lpdA GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385 Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim PJD2_k127_6205028_4 323261.Noc_1255 5.883e-142 463.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales 135613|Chromatiales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding PJD2_k127_6205028_0 945713.IALB_2978 0.0 1279.0 COG2609@1|root,COG2609@2|Bacteria 2|Bacteria C pyruvate dehydrogenase (acetyl-transferring) activity aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N PJD2_k127_6205028_11 404589.Anae109_4173 3.851e-50 188.0 COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,432D0@68525|delta/epsilon subdivisions,2WY0P@28221|Deltaproteobacteria,2Z211@29|Myxococcales 28221|Deltaproteobacteria C Oxidoreductase NAD-binding domain - - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 PJD2_k127_622662_2 880071.Fleli_2125 6.989e-08 66.0 COG2931@1|root,COG2931@2|Bacteria,4NU1P@976|Bacteroidetes,47XBG@768503|Cytophagia 976|Bacteroidetes Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS PJD2_k127_622662_1 459349.CLOAM0575 1.106e-47 197.0 COG4412@1|root,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria 2|Bacteria S Evidence 5 No homology to any previously reported sequences - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - CarboxypepD_reg,FlgD_ig,Peptidase_M6 PJD2_k127_622662_3 1379698.RBG1_1C00001G1235 3.568e-06 59.0 COG1470@1|root,COG1470@2|Bacteria 2|Bacteria S cell adhesion involved in biofilm formation - - - - - - - - - - - - CarbopepD_reg_2 PJD2_k127_622662_0 1379698.RBG1_1C00001G1236 2.816e-49 186.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - ko:K06882 - - - - ko00000 - - - fn3 PJD2_k127_6230900_3 880073.Calab_0541 1.575e-49 178.0 COG1993@1|root,COG1993@2|Bacteria,2NPXF@2323|unclassified Bacteria 2|Bacteria T Uncharacterized ACR, COG1993 - - - ko:K06199,ko:K09137 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CBS,DUF190 PJD2_k127_6230900_0 929703.KE386491_gene2333 2.635e-110 370.0 COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin PJD2_k127_6230900_1 861299.J421_2922 6.677e-85 291.0 COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 PJD2_k127_6255289_3 1174528.JH992893_gene5979 1.063e-16 91.0 COG0655@1|root,COG0655@2|Bacteria 2|Bacteria S NAD(P)H dehydrogenase (quinone) activity yhcB GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red PJD2_k127_6255289_0 246197.MXAN_5983 1.31e-74 257.0 COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,43BAG@68525|delta/epsilon subdivisions,2X6PP@28221|Deltaproteobacteria,2YUZG@29|Myxococcales 28221|Deltaproteobacteria H O-methyltransferase - - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 PJD2_k127_6255289_1 880073.Calab_3331 2.377e-49 196.0 2919D@1|root,2ZNWG@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_6255289_2 1408473.JHXO01000005_gene1865 3.785e-35 142.0 COG0484@1|root,COG0484@2|Bacteria,4NPS0@976|Bacteroidetes,2FXKU@200643|Bacteroidia 976|Bacteroidetes O heat shock protein binding - - - - - - - - - - - - - PJD2_k127_6263056_3 246197.MXAN_2071 2.754e-59 218.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2YVB2@29|Myxococcales 28221|Deltaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C,TruB_C_2,TruB_N PJD2_k127_6263056_2 153721.MYP_2312 1.938e-65 242.0 COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia 976|Bacteroidetes H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase PJD2_k127_6263056_5 246194.CHY_1760 2.005e-29 119.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales 186801|Clostridia J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 PJD2_k127_6263056_0 1191523.MROS_1723 5.04e-232 739.0 COG1185@1|root,COG1185@2|Bacteria 2|Bacteria J polyribonucleotide nucleotidyltransferase activity pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 PJD2_k127_6263056_1 1379698.RBG1_1C00001G1161 1.262e-84 297.0 COG0612@1|root,COG0612@2|Bacteria,2NNW3@2323|unclassified Bacteria 2|Bacteria S Belongs to the peptidase M16 family pepR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Peptidase_M16,Peptidase_M16_C PJD2_k127_6263056_4 1379698.RBG1_1C00001G1162 1.223e-48 187.0 COG0726@1|root,COG0726@2|Bacteria,2NPY1@2323|unclassified Bacteria 2|Bacteria G Polysaccharide deacetylase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Polysacc_deac_1 PJD2_k127_6263667_4 574087.Acear_0231 1.418e-12 78.0 COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia 186801|Clostridia U PFAM TadE family protein - - - - - - - - - - - - TadE PJD2_k127_6263667_2 1267534.KB906755_gene4078 1.49e-14 84.0 COG4960@1|root,COG4960@2|Bacteria 2|Bacteria OU Type IV leader peptidase family cpaA1 - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 PJD2_k127_6263667_5 240015.ACP_1103 5.305e-06 53.0 COG3847@1|root,COG3847@2|Bacteria,3Y5Y3@57723|Acidobacteria,2JNT7@204432|Acidobacteriia 204432|Acidobacteriia U PFAM Flp Fap pilin component - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - - PJD2_k127_6263667_1 404380.Gbem_1052 3.423e-17 85.0 COG1430@1|root,COG1430@2|Bacteria 2|Bacteria S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 PJD2_k127_6263667_3 1121403.AUCV01000049_gene2164 1.936e-13 78.0 COG1989@1|root,COG1989@2|Bacteria,1R34X@1224|Proteobacteria,42V6M@68525|delta/epsilon subdivisions,2WRP6@28221|Deltaproteobacteria 28221|Deltaproteobacteria NOU PFAM peptidase A24A, prepilin type IV - - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 PJD2_k127_6263667_0 1499967.BAYZ01000033_gene1128 5.068e-291 905.0 COG1217@1|root,COG1217@2|Bacteria,2NNY7@2323|unclassified Bacteria 2|Bacteria T Elongation factor G C-terminus typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 PJD2_k127_6265775_3 1089455.MOPEL_032_00220 2.778e-45 179.0 COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4F6MV@85018|Dermatophilaceae 201174|Actinobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 PJD2_k127_6265775_8 883156.HMPREF9282_00049 9.773e-09 62.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4H4A5@909932|Negativicutes 909932|Negativicutes K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ PJD2_k127_6265775_6 765420.OSCT_2915 6.717e-12 79.0 COG0500@1|root,COG2226@2|Bacteria,2GA7Z@200795|Chloroflexi,375F2@32061|Chloroflexia 32061|Chloroflexia Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_23 PJD2_k127_6265775_9 42256.RradSPS_1688 4.077e-07 63.0 COG1807@1|root,COG1807@2|Bacteria,2GNPY@201174|Actinobacteria 201174|Actinobacteria M capsule polysaccharide biosynthetic process - - - - - - - - - - - - - PJD2_k127_6265775_2 518766.Rmar_1322 1.157e-52 206.0 COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1FIXH@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_6265775_4 324602.Caur_0837 1.031e-22 109.0 COG5653@1|root,COG5653@2|Bacteria 2|Bacteria M Protein involved in cellulose biosynthesis - - - - - - - - - - - - Acetyltransf_6 PJD2_k127_6265775_1 304371.MCP_0774 7.166e-122 408.0 COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,2NAHC@224756|Methanomicrobia 224756|Methanomicrobia E Beta-eliminating lyase - - - - - - - - - - - - DegT_DnrJ_EryC1 PJD2_k127_6265775_0 926569.ANT_22620 1.977e-122 419.0 COG1086@1|root,COG1086@2|Bacteria,2G5M8@200795|Chloroflexi 200795|Chloroflexi GM Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 PJD2_k127_6265775_5 1123377.AUIV01000024_gene123 4.624e-16 93.0 COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X4Y5@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y PJD2_k127_6265775_7 1122182.KB903833_gene5539 1.171e-09 63.0 COG2148@1|root,COG2148@2|Bacteria,2HID3@201174|Actinobacteria,4DH8M@85008|Micromonosporales 201174|Actinobacteria M Bacterial sugar transferase - - - - - - - - - - - - Bac_transf PJD2_k127_6325094_3 933262.AXAM01000020_gene27 6.18e-78 269.0 COG0491@1|root,COG0491@2|Bacteria,1R4FA@1224|Proteobacteria,42TD1@68525|delta/epsilon subdivisions,2WPPD@28221|Deltaproteobacteria,2MQ1T@213118|Desulfobacterales 28221|Deltaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B PJD2_k127_6325094_8 880073.Calab_0080 1.059e-33 136.0 COG0393@1|root,COG0393@2|Bacteria,2NPZJ@2323|unclassified Bacteria 2|Bacteria S Putative heavy-metal-binding - - - - - - - - - - - - YbjQ_1 PJD2_k127_6325094_6 880073.Calab_0082 2.309e-37 149.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_6325094_7 383372.Rcas_2505 4.081e-34 150.0 COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia 32061|Chloroflexia M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - PJD2_k127_6325094_0 880073.Calab_2784 5.755e-163 533.0 COG1164@1|root,COG1164@2|Bacteria,2NQ8K@2323|unclassified Bacteria 2|Bacteria E Oligoendopeptidase f - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2,Peptidase_M3 PJD2_k127_6325094_2 926550.CLDAP_16500 3.377e-149 481.0 COG0158@1|root,COG0158@2|Bacteria 2|Bacteria G fructose 1,6-bisphosphate 1-phosphatase activity fbp GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - iUTI89_1310.UTI89_C4836,ic_1306.c5329 FBPase PJD2_k127_6325094_1 945713.IALB_1250 7.527e-152 494.0 COG1690@1|root,COG1690@2|Bacteria 2|Bacteria S RNA ligase activity rtcB GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB PJD2_k127_6325094_5 314230.DSM3645_22496 1.062e-37 152.0 COG1912@1|root,COG1912@2|Bacteria,2IZNZ@203682|Planctomycetes 203682|Planctomycetes S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans PJD2_k127_6325094_4 1480694.DC28_07915 1.08e-45 177.0 COG1752@1|root,COG1752@2|Bacteria,2J6JW@203691|Spirochaetes 203691|Spirochaetes M esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,Patatin PJD2_k127_640071_1 439235.Dalk_4320 3.401e-11 74.0 2DS9E@1|root,32VU1@2|Bacteria,1P3D6@1224|Proteobacteria,431R2@68525|delta/epsilon subdivisions,2WW7F@28221|Deltaproteobacteria,2MNTP@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_640071_0 204669.Acid345_1475 1.996e-30 126.0 COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria,2JJXH@204432|Acidobacteriia 204432|Acidobacteriia E Cys/Met metabolism PLP-dependent enzyme - - - - - - - - - - - - Aminotran_1_2 PJD2_k127_649061_3 765911.Thivi_3948 5.124e-58 209.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WXMC@135613|Chromatiales 135613|Chromatiales T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat PJD2_k127_649061_4 215803.DB30_7576 6.362e-14 83.0 COG0457@1|root,COG0457@2|Bacteria,1PJE3@1224|Proteobacteria,439H8@68525|delta/epsilon subdivisions,2X4TF@28221|Deltaproteobacteria,2YZJP@29|Myxococcales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2 PJD2_k127_649061_0 234267.Acid_4431 1.617e-201 659.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 PJD2_k127_649061_1 269799.Gmet_2367 1.375e-72 266.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales 28221|Deltaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase PJD2_k127_649061_2 697281.Mahau_0324 3.472e-69 246.0 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24G9W@186801|Clostridia,42HNI@68295|Thermoanaerobacterales 186801|Clostridia S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C PJD2_k127_670257_6 457570.Nther_2043 6.24e-08 65.0 COG1664@1|root,COG1664@2|Bacteria,1VBC3@1239|Firmicutes,24NSR@186801|Clostridia 186801|Clostridia M Polymer-forming cytoskeletal - - - - - - - - - - - - - PJD2_k127_670257_9 264732.Moth_2363 0.0001838 52.0 COG5662@1|root,COG5662@2|Bacteria,1VC8Y@1239|Firmicutes,24NRN@186801|Clostridia,42GY2@68295|Thermoanaerobacterales 186801|Clostridia K Putative zinc-finger - - - - - - - - - - - - DUF4349,zf-HC2 PJD2_k127_670257_5 458817.Shal_4183 4.803e-13 81.0 COG3595@1|root,COG3595@2|Bacteria,1RI1P@1224|Proteobacteria,1RRZW@1236|Gammaproteobacteria,2QB2H@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF4097 PJD2_k127_670257_3 880073.Calab_1183 1.605e-49 185.0 COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria 2|Bacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_670257_0 868595.Desca_2508 6.246e-187 597.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,2600A@186807|Peptococcaceae 186801|Clostridia G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N PJD2_k127_670257_8 330214.NIDE2912 1.386e-05 53.0 COG2919@1|root,COG2919@2|Bacteria 2|Bacteria D cell cycle ftsB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - ko:K05589 - - - - ko00000,ko03036 - - - DivIC PJD2_k127_670257_7 1231057.AMGD01000104_gene265 4.783e-07 61.0 2EHF3@1|root,33B70@2|Bacteria,1VP4D@1239|Firmicutes,4HZXQ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - PJD2_k127_670257_2 204669.Acid345_0824 3.033e-131 437.0 COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JKYK@204432|Acidobacteriia 204432|Acidobacteriia S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS PJD2_k127_670257_4 1379698.RBG1_1C00001G1353 2.231e-14 86.0 COG0457@1|root,COG0457@2|Bacteria,2NRIR@2323|unclassified Bacteria 2|Bacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11,TPR_16,TPR_2,TPR_8 PJD2_k127_670257_1 452637.Oter_2945 7.033e-180 606.0 COG0457@1|root,COG0457@2|Bacteria 452637.Oter_2945|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - PJD2_k127_676903_4 1322246.BN4_11065 6.435e-25 106.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WRRT@28221|Deltaproteobacteria,2MCID@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM RNP-1 like RNA-binding protein - - - - - - - - - - - - RRM_1 PJD2_k127_676903_0 1408473.JHXO01000006_gene1316 8.409e-141 459.0 COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,2FRWR@200643|Bacteroidia 976|Bacteroidetes I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C PJD2_k127_676903_1 373903.Hore_13580 1.199e-95 332.0 COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales 186801|Clostridia C B12 binding domain - - - - - - - - - - - - B12-binding,DUF4080,Radical_SAM PJD2_k127_676903_3 926550.CLDAP_29650 5.883e-26 116.0 COG1503@1|root,COG1503@2|Bacteria,2G6UJ@200795|Chloroflexi 200795|Chloroflexi J translation release factor activity - - - - - - - - - - - - - PJD2_k127_676903_2 1379270.AUXF01000001_gene2611 3.529e-26 109.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - ko:K07782 ko02020,ko02024,ko02026,map02020,map02024,map02026 - - - ko00000,ko00001,ko03000 - - - GAF_2,GerE,PocR,Response_reg PJD2_k127_677697_11 580331.Thit_0651 1.037e-23 115.0 COG0438@1|root,COG0438@2|Bacteria,1V4TS@1239|Firmicutes,25BS3@186801|Clostridia 186801|Clostridia M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 PJD2_k127_677697_1 246194.CHY_1561 2.73e-143 466.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,42FBT@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b PJD2_k127_677697_0 56780.SYN_00304 4.657e-151 503.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2X708@28221|Deltaproteobacteria,2MSKI@213462|Syntrophobacterales 28221|Deltaproteobacteria M Transglycosylase - - 2.4.1.129,3.4.16.4 ko:K05366,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase PJD2_k127_677697_7 929556.Solca_0196 4.191e-61 237.0 COG1075@1|root,COG1075@2|Bacteria,4NJMQ@976|Bacteroidetes,1IYWC@117747|Sphingobacteriia 976|Bacteroidetes S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - DUF676,PGAP1 PJD2_k127_677697_14 880073.Calab_2081 3.964e-19 103.0 COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria 2|Bacteria P LVIVD repeat - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - LVIVD PJD2_k127_677697_2 1121430.JMLG01000003_gene532 3.431e-140 458.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae 186801|Clostridia G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB - 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme PJD2_k127_677697_4 56780.SYN_01482 5.424e-92 316.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,2MQVF@213462|Syntrophobacterales 28221|Deltaproteobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N PJD2_k127_677697_8 237368.SCABRO_01223 4.023e-52 201.0 COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes 203682|Planctomycetes C 5'-nucleotidase - - - - - - - - - - - - Cytochrome_C554 PJD2_k127_677697_9 880073.Calab_2402 2.047e-41 176.0 28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_677697_5 760568.Desku_0806 1.701e-89 305.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae 186801|Clostridia C electron transfer flavoprotein, alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha,Fer4 PJD2_k127_677697_6 56780.SYN_02636 1.833e-69 248.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales 28221|Deltaproteobacteria C Electron transfer flavoprotein domain etfB - - ko:K03521 - - - - ko00000 - - - ETF PJD2_k127_677697_3 240302.BN982_01080 1.088e-131 432.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,3NDAF@45667|Halobacillus 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain acdA - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_677697_13 880073.Calab_0921 1.945e-20 108.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF4157,FctA,Peptidase_M43 PJD2_k127_677697_10 523845.AQXV01000026_gene1469 9.262e-32 145.0 arCOG02545@1|root,arCOG02545@2157|Archaea 2157|Archaea S Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - Beta_helix,NosD,PKD PJD2_k127_677697_12 945713.IALB_2396 1.441e-21 101.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - FlgD_ig,Sortilin-Vps10 PJD2_k127_684823_0 290397.Adeh_0093 6.599e-79 278.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2YUDC@29|Myxococcales 28221|Deltaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 PJD2_k127_684823_4 457405.FSDG_02026 0.0005852 51.0 COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,3799H@32066|Fusobacteria 32066|Fusobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6,TPR_8 PJD2_k127_684823_3 385682.AFSL01000084_gene1090 3.337e-18 95.0 COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,2FNAY@200643|Bacteroidia,3XJCH@558415|Marinilabiliaceae 976|Bacteroidetes S Outer membrane lipoprotein yfiO - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO PJD2_k127_684823_2 1286171.EAL2_c11660 9.485e-32 140.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,25WQX@186806|Eubacteriaceae 186801|Clostridia H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like PJD2_k127_684823_1 889378.Spiaf_2716 3.447e-44 167.0 COG0749@1|root,COG0749@2|Bacteria,2J5FM@203691|Spirochaetes 203691|Spirochaetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 PJD2_k127_696502_3 1174528.JH992893_gene5979 2.947e-20 104.0 COG0655@1|root,COG0655@2|Bacteria 2|Bacteria S NAD(P)H dehydrogenase (quinone) activity yhcB GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red PJD2_k127_696502_1 1121920.AUAU01000004_gene896 9.729e-69 249.0 COG1575@1|root,COG2249@1|root,COG1575@2|Bacteria,COG2249@2|Bacteria,3Y5PA@57723|Acidobacteria 57723|Acidobacteria H NADPH-dependent FMN reductase - - - - - - - - - - - - Flavodoxin_2 PJD2_k127_696502_4 404589.Anae109_4124 0.0001822 52.0 COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WS8K@28221|Deltaproteobacteria 28221|Deltaproteobacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 PJD2_k127_696502_0 945713.IALB_1500 5.067e-130 436.0 COG4232@1|root,COG4232@2|Bacteria 2|Bacteria CO protein-disulfide reductase activity dsbD - 1.8.1.8 ko:K04084,ko:K06196 - - - - ko00000,ko01000,ko02000,ko03110 5.A.1.1,5.A.1.2 - - DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7 PJD2_k127_696502_2 1380394.JADL01000004_gene5722 1.728e-43 165.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria,2JR7S@204441|Rhodospirillales 204441|Rhodospirillales Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase PJD2_k127_747268_1 880073.Calab_1380 6.209e-59 208.0 COG1190@1|root,COG1190@2|Bacteria,2NNMH@2323|unclassified Bacteria 2|Bacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DUF4332,tRNA-synt_2,tRNA_anti-codon PJD2_k127_747268_0 96561.Dole_2846 8.048e-80 281.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MHM1@213118|Desulfobacterales 28221|Deltaproteobacteria M TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD PJD2_k127_786171_2 388051.AUFE01000010_gene2626 1.158e-121 395.0 COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2VHSP@28216|Betaproteobacteria,1K3GF@119060|Burkholderiaceae 28216|Betaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family abmC - - - - - - - - - - - ECH_1 PJD2_k127_786171_1 1411123.JQNH01000001_gene279 1.639e-140 462.0 COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria 28211|Alphaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N PJD2_k127_786171_4 883126.HMPREF9710_02750 2.061e-43 171.0 COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2VSJ7@28216|Betaproteobacteria,47795@75682|Oxalobacteraceae 28216|Betaproteobacteria J Endoribonuclease L-PSP abmE - - - - - - - - - - - Ribonuc_L-PSP PJD2_k127_786171_0 1254432.SCE1572_12170 5.649e-228 719.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PFAM AMP-dependent synthetase and ligase bamY - 6.2.1.25 ko:K04110 ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120 - R01422 RC00004,RC00174 ko00000,ko00001,ko01000 - - iAF987.Gmet_2143 AMP-binding,AMP-binding_C PJD2_k127_786171_3 1192034.CAP_0949 8.061e-78 268.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales 28221|Deltaproteobacteria S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase PJD2_k127_786171_6 266940.Krad_3974 0.0006577 50.0 COG1277@1|root,COG1277@2|Bacteria 2|Bacteria - - - - - ko:K01992,ko:K19310 ko02010,map02010 M00254,M00747 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.131.1 - - ABC2_membrane_2,ABC2_membrane_4 PJD2_k127_786171_5 234267.Acid_7689 1.798e-12 71.0 COG1131@1|root,COG1131@2|Bacteria,3Y6U6@57723|Acidobacteria 57723|Acidobacteria V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran PJD2_k127_800962_0 1121430.JMLG01000022_gene2418 7.705e-133 442.0 COG3829@1|root,COG3829@2|Bacteria,1V0EF@1239|Firmicutes,24DXA@186801|Clostridia 186801|Clostridia KT Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,PAS_9,Sigma54_activat PJD2_k127_800962_2 397945.Aave_4282 3.267e-17 90.0 COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,2VY0W@28216|Betaproteobacteria,4AHAS@80864|Comamonadaceae 28216|Betaproteobacteria S Transmembrane exosortase (Exosortase_EpsH) - - - - - - - - - - - - Exosortase_EpsH PJD2_k127_800962_4 379066.GAU_1417 2.832e-10 72.0 2DUTE@1|root,33S5W@2|Bacteria,1ZSMI@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - PJD2_k127_800962_1 243231.GSU2569 5.95e-86 299.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans PJD2_k127_800962_3 1385935.N836_03830 2.586e-11 73.0 COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales 1117|Cyanobacteria L Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8 PJD2_k127_802189_13 309801.trd_0460 1.298e-53 202.0 COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi,27XPC@189775|Thermomicrobia 189775|Thermomicrobia L May be involved in recombinational repair of damaged DNA - - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N PJD2_k127_802189_14 562970.Btus_0742 1.33e-52 199.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,277YD@186823|Alicyclobacillaceae 91061|Bacilli H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase PJD2_k127_802189_2 401526.TcarDRAFT_1596 1.344e-214 687.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H236@909932|Negativicutes 909932|Negativicutes H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C PJD2_k127_802189_19 888055.HMPREF9015_00732 1.521e-16 85.0 COG1963@1|root,COG1963@2|Bacteria,37A36@32066|Fusobacteria 32066|Fusobacteria S Psort location CytoplasmicMembrane, score 9.46 - - - ko:K09775 - - - - ko00000 - - - DUF212 PJD2_k127_802189_12 1159870.KB907784_gene2741 4.927e-60 219.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,3T1JI@506|Alcaligenaceae 28216|Betaproteobacteria H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10 ko:K00795 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364 R01658,R02003 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt PJD2_k127_802189_21 1120973.AQXL01000127_gene2747 5.13e-06 57.0 COG1722@1|root,COG1722@2|Bacteria,1TU8H@1239|Firmicutes,4I3UU@91061|Bacilli,278PT@186823|Alicyclobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S PJD2_k127_802189_8 1304880.JAGB01000001_gene100 4.541e-97 331.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia 186801|Clostridia L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 PJD2_k127_802189_9 547042.BACCOPRO_03800 1.856e-93 322.0 COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,2FMNT@200643|Bacteroidia,4AN29@815|Bacteroidaceae 976|Bacteroidetes F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C PJD2_k127_802189_11 243231.GSU1138 4.279e-86 293.0 COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales 28221|Deltaproteobacteria S YmdB-like protein - - - ko:K09769 - - - - ko00000 - - - YmdB PJD2_k127_802189_3 1379698.RBG1_1C00001G1123 1.347e-164 533.0 COG1418@1|root,COG1418@2|Bacteria,2NNU5@2323|unclassified Bacteria 2|Bacteria S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 PJD2_k127_802189_22 926561.KB900622_gene706 1.125e-05 51.0 COG3027@1|root,COG3027@2|Bacteria 2|Bacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA PJD2_k127_802189_4 1125863.JAFN01000001_gene1869 3.766e-160 533.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Phenylalanyl-tRNA synthetase, beta subunit pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind PJD2_k127_802189_7 580331.Thit_1517 1.344e-120 395.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,42EPG@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d PJD2_k127_802189_16 696369.KI912183_gene906 1.644e-43 161.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,2627I@186807|Peptococcaceae 186801|Clostridia J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT - - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 PJD2_k127_802189_18 1121918.ARWE01000001_gene1305 6.816e-18 88.0 COG0291@1|root,COG0291@2|Bacteria,1QDQ4@1224|Proteobacteria,42VSG@68525|delta/epsilon subdivisions,2WREY@28221|Deltaproteobacteria,43SRN@69541|Desulfuromonadales 28221|Deltaproteobacteria J Ribosomal protein L35 rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p PJD2_k127_802189_15 485915.Dret_0044 9.154e-52 192.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2M933@213115|Desulfovibrionales 28221|Deltaproteobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N PJD2_k127_802189_1 1123371.ATXH01000013_gene1505 1.814e-217 694.0 COG0441@1|root,COG0441@2|Bacteria,2GH53@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_SAD PJD2_k127_802189_0 880073.Calab_2438 6.593e-270 844.0 COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria 2|Bacteria O Heat shock 70 kDa protein dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 PJD2_k127_802189_10 1379698.RBG1_1C00001G0474 3.083e-91 316.0 COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria 2|Bacteria J Poly A polymerase head domain cca - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 PJD2_k127_802189_17 1156937.MFUM_1010095 2.339e-21 105.0 COG0392@1|root,COG0392@2|Bacteria,46T31@74201|Verrucomicrobia,37GPN@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM PJD2_k127_802189_20 373903.Hore_22330 5.123e-16 80.0 2DG7P@1|root,2ZUUE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_802189_6 525904.Tter_0039 9.824e-136 442.0 COG2046@1|root,COG2046@2|Bacteria,2NNS5@2323|unclassified Bacteria 2|Bacteria P PUA-like domain sat - 2.7.1.25,2.7.7.4 ko:K00958,ko:K13811 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 PJD2_k127_802189_5 1303518.CCALI_01333 3.342e-157 508.0 COG3379@1|root,COG3379@2|Bacteria 2|Bacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_805660_9 1297742.A176_03035 1.876e-12 67.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WTZ0@28221|Deltaproteobacteria,2YUKM@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran PJD2_k127_805660_4 266117.Rxyl_0432 5.775e-38 147.0 COG1504@1|root,COG1504@2|Bacteria,2IRTB@201174|Actinobacteria 201174|Actinobacteria S Protein of unknown function (DUF498/DUF598) - - - - - - - - - - - - DUF498 PJD2_k127_805660_3 251221.35212797 1.997e-49 183.0 COG1670@1|root,COG1670@2|Bacteria,1G5HU@1117|Cyanobacteria 1117|Cyanobacteria J PFAM Acetyltransferase (GNAT) family - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 PJD2_k127_805660_1 1123278.KB893552_gene3733 6.837e-73 255.0 COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,47N4V@768503|Cytophagia 976|Bacteroidetes I PFAM Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase PJD2_k127_805660_6 706587.Desti_0737 2.553e-21 99.0 COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria 1224|Proteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1 PJD2_k127_805660_8 1231241.Mc24_02398 3.434e-14 85.0 COG0296@1|root,COG0296@2|Bacteria,2GD7U@200918|Thermotogae 200918|Thermotogae G PFAM glycoside hydrolase, family 13 domain protein - - - - - - - - - - - - AMPK1_CBM PJD2_k127_805660_7 309807.SRU_2758 8.819e-19 95.0 COG0296@1|root,COG0296@2|Bacteria 2|Bacteria G 1,4-alpha-glucan branching enzyme activity - - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48 PJD2_k127_805660_5 644966.Tmar_0414 5.948e-27 123.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WDGI@538999|Clostridiales incertae sedis 186801|Clostridia K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 PJD2_k127_805660_2 1304885.AUEY01000001_gene3202 2.887e-52 189.0 COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2MJU4@213118|Desulfobacterales 28221|Deltaproteobacteria T Low molecular weight phosphotyrosine protein phosphatase arsC - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc PJD2_k127_805660_0 1121918.ARWE01000001_gene2083 4.184e-129 422.0 COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria 28221|Deltaproteobacteria P PFAM Bile acid sodium symporter arsB - - ko:K03325 - - - - ko00000,ko02000 2.A.59 - - SBF PJD2_k127_849780_1 1144275.COCOR_07662 4.2e-166 538.0 COG0308@1|root,COG1668@1|root,COG0308@2|Bacteria,COG1668@2|Bacteria,1PTWJ@1224|Proteobacteria 1224|Proteobacteria E Peptidase family M1 domain - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4,Peptidase_M1 PJD2_k127_849780_2 394221.Mmar10_1711 1.024e-110 366.0 COG1235@1|root,COG1235@2|Bacteria,1PVWC@1224|Proteobacteria,2V746@28211|Alphaproteobacteria,43Z2A@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Beta-lactamase superfamily domain - - - ko:K06136 - - - - ko00000 - - - Lactamase_B_2 PJD2_k127_849780_5 1340493.JNIF01000003_gene2275 5.334e-50 203.0 COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,3Y2P9@57723|Acidobacteria 57723|Acidobacteria KT Stage II sporulation protein E - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - HAMP,SpoIIE PJD2_k127_849780_3 1047013.AQSP01000099_gene1506 1.355e-91 319.0 COG1355@1|root,COG1355@2|Bacteria,2NQS3@2323|unclassified Bacteria 2|Bacteria S Memo-like protein - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo PJD2_k127_849780_6 314230.DSM3645_16160 1.965e-28 132.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - ICMT,PEMT PJD2_k127_849780_4 713586.KB900536_gene1447 3.796e-73 259.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1WWA8@135613|Chromatiales 135613|Chromatiales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 PJD2_k127_849780_0 572477.Alvin_2517 0.0 1054.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW0R@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran PJD2_k127_894062_1 391625.PPSIR1_21764 1.589e-44 163.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,43C2Q@68525|delta/epsilon subdivisions,2WSJ0@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4 PJD2_k127_894062_0 1379698.RBG1_1C00001G0383 2.304e-55 207.0 COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria 2|Bacteria M glycosyl transferase group 1 remC - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 PJD2_k127_894062_2 313595.P700755_002010 1.327e-15 79.0 COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1I17S@117743|Flavobacteriia,4C3Q8@83612|Psychroflexus 976|Bacteroidetes FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam PJD2_k127_925593_6 517418.Ctha_2048 2.444e-39 151.0 COG0665@1|root,COG0665@2|Bacteria 2|Bacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity thiO - 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO PJD2_k127_925593_0 485913.Krac_9382 5.677e-270 853.0 COG1505@1|root,COG1505@2|Bacteria,2GBNH@200795|Chloroflexi 200795|Chloroflexi E Peptidase S9, prolyl oligopeptidase active site domain protein - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N PJD2_k127_925593_2 1137269.AZWL01000005_gene2155 3.531e-143 462.0 COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria 201174|Actinobacteria Q Methyltransferase type 11 - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 PJD2_k127_925593_3 156889.Mmc1_3480 8.916e-97 343.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria 1224|Proteobacteria T radical SAM - - - - - - - - - - - - DUF3641,Fer4_12,Radical_SAM PJD2_k127_925593_1 1297742.A176_05284 5.643e-145 474.0 COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales 28221|Deltaproteobacteria M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3 PJD2_k127_925593_4 237368.SCABRO_01833 1.024e-55 211.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - 2.7.8.20 ko:K01002,ko:K20534 ko01100,map01100 - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - GT87,Glycos_transf_2 PJD2_k127_925593_5 595460.RRSWK_02045 2.17e-53 203.0 COG1215@1|root,COG1215@2|Bacteria,2J562@203682|Planctomycetes 203682|Planctomycetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 PJD2_k127_950444_0 1232410.KI421414_gene2861 4.803e-73 257.0 COG1899@1|root,COG1899@2|Bacteria,1R3WQ@1224|Proteobacteria,42M57@68525|delta/epsilon subdivisions,2WJ6N@28221|Deltaproteobacteria,43RXI@69541|Desulfuromonadales 28221|Deltaproteobacteria O peptidyl-lysine modification to peptidyl-hypusine - - - - - - - - - - - - - PJD2_k127_950444_2 1379698.RBG1_1C00001G1249 5.216e-65 231.0 COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria 2|Bacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 PJD2_k127_950444_1 1125863.JAFN01000001_gene535 1.488e-69 258.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 PJD2_k127_950444_4 479434.Sthe_0849 9.356e-52 197.0 COG0438@1|root,COG0438@2|Bacteria,2G8W3@200795|Chloroflexi,27Y3X@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 PJD2_k127_950444_3 373903.Hore_18870 2.864e-53 210.0 COG1216@1|root,COG1216@2|Bacteria,1UIHC@1239|Firmicutes,25F9A@186801|Clostridia,3WADS@53433|Halanaerobiales 186801|Clostridia S PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 PJD2_k127_950444_5 1125863.JAFN01000001_gene542 3.084e-27 125.0 COG0859@1|root,COG0859@2|Bacteria,1R5M8@1224|Proteobacteria,42N36@68525|delta/epsilon subdivisions,2WM92@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM glycosyl transferase family 9 - - - ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 PJD2_k127_950444_6 641147.HMPREF9021_00601 1.652e-08 56.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KQG4@206351|Neisseriales 206351|Neisseriales M Psort location Cytoplasmic, score 8.96 rfaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 PJD2_k127_954587_1 1121438.JNJA01000001_gene2516 3.083e-10 68.0 COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2M8ME@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest PJD2_k127_954587_0 1134912.AJTV01000030_gene2088 1.915e-91 332.0 COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,1MYCW@1224|Proteobacteria 1224|Proteobacteria Q Belongs to the peptidase S8 family - - - - - - - - - - - - PA PJD2_k127_965173_8 1121403.AUCV01000021_gene3558 1.567e-19 102.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales 28221|Deltaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA PJD2_k127_965173_4 1232410.KI421428_gene1064 1.999e-40 151.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42TQU@68525|delta/epsilon subdivisions,2WQ3A@28221|Deltaproteobacteria,43V6N@69541|Desulfuromonadales 28221|Deltaproteobacteria O PFAM PpiC-type peptidyl-prolyl cis-trans isomerase ppiC - 5.2.1.8 ko:K01802,ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SseB PJD2_k127_965173_3 1123371.ATXH01000001_gene1188 4.119e-48 182.0 2CHNQ@1|root,2Z7KM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - PJD2_k127_965173_7 243231.GSU1608 1.882e-20 92.0 2CHNQ@1|root,2Z7KM@2|Bacteria,1REIJ@1224|Proteobacteria,42S2X@68525|delta/epsilon subdivisions,2WN8J@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - PJD2_k127_965173_0 1173024.KI912148_gene4723 6.57e-76 262.0 COG3340@1|root,COG3340@2|Bacteria,1GCCZ@1117|Cyanobacteria,1JKEU@1189|Stigonemataceae 1117|Cyanobacteria E Peptidase family S51 - - - - - - - - - - - - Peptidase_S51 PJD2_k127_965173_2 204669.Acid345_2786 3.116e-57 216.0 COG0229@1|root,COG0229@2|Bacteria,3Y4XW@57723|Acidobacteria,2JMYE@204432|Acidobacteriia 204432|Acidobacteriia C SelR domain - - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR PJD2_k127_965173_5 1297742.A176_00411 2.975e-35 145.0 COG1378@1|root,COG1378@2|Bacteria,1N9ZU@1224|Proteobacteria,42NVG@68525|delta/epsilon subdivisions,2WMD1@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Sugar-specific transcriptional regulator TrmB - - - - - - - - - - - - Regulator_TrmB,TrmB PJD2_k127_965173_1 1121423.JONT01000011_gene253 1.184e-72 258.0 COG0382@1|root,COG0382@2|Bacteria,1TQU5@1239|Firmicutes,2486B@186801|Clostridia,25ZZE@186807|Peptococcaceae 186801|Clostridia H PFAM UbiA prenyltransferase - - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA PJD2_k127_965173_6 765911.Thivi_3617 1.135e-28 120.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1WWQJ@135613|Chromatiales 135613|Chromatiales H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein PJD2_k127_975140_22 1005999.GLGR_1793 2.702e-35 137.0 COG0204@1|root,COG0204@2|Bacteria,1RA8V@1224|Proteobacteria,1S4RP@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Acyltransferase - - - - - - - - - - - - Acyltransferase PJD2_k127_975140_11 794903.OPIT5_06810 3.631e-107 356.0 COG4589@1|root,COG4589@2|Bacteria,46T6E@74201|Verrucomicrobia 74201|Verrucomicrobia S Cytidylyltransferase family - - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 PJD2_k127_975140_16 666681.M301_2184 2.473e-51 201.0 COG0558@1|root,COG0558@2|Bacteria,1RE0I@1224|Proteobacteria,2VR68@28216|Betaproteobacteria 28216|Betaproteobacteria I CDP-alcohol phosphatidyltransferase - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf PJD2_k127_975140_6 1313301.AUGC01000001_gene1573 2.464e-137 447.0 COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes 976|Bacteroidetes C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red PJD2_k127_975140_13 1499967.BAYZ01000145_gene6200 2.758e-65 235.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 PJD2_k127_975140_9 1123276.KB893290_gene5329 1.459e-110 383.0 COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,47JW1@768503|Cytophagia 976|Bacteroidetes E Peptidase M1, membrane alanine aminopeptidase pepN1 - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 PJD2_k127_975140_24 211165.AJLN01000116_gene3277 4.038e-07 60.0 2ETKY@1|root,33M4N@2|Bacteria,1GF86@1117|Cyanobacteria,1JM2E@1189|Stigonemataceae 1117|Cyanobacteria - - - - - - - - - - - - - - - PJD2_k127_975140_20 1499967.BAYZ01000158_gene452 7.078e-43 163.0 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding ykgJ - - ko:K06940 - - - - ko00000 - - - CxxCxxCC PJD2_k127_975140_1 765912.Thimo_1619 0.0 1305.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,1WW62@135613|Chromatiales 135613|Chromatiales L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon PJD2_k127_975140_19 489825.LYNGBM3L_50810 9.325e-45 172.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB_2 PJD2_k127_975140_3 1519464.HY22_10360 4.397e-211 676.0 COG0154@1|root,COG0154@2|Bacteria,1FDMC@1090|Chlorobi 2|Bacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase PJD2_k127_975140_5 502025.Hoch_6598 3.571e-183 584.0 COG0493@1|root,COG0493@2|Bacteria,1P58U@1224|Proteobacteria,4392A@68525|delta/epsilon subdivisions,2X47Z@28221|Deltaproteobacteria,2YYG2@29|Myxococcales 28221|Deltaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase - - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - Pyr_redox_2 PJD2_k127_975140_4 234831.PSM_A0515 1.319e-189 623.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,2PZTK@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M ERAP1-like C-terminal domain - - 3.4.11.14,3.4.11.2 ko:K01256,ko:K01263 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 PJD2_k127_975140_23 330214.NIDE3836 4.124e-13 78.0 COG2197@1|root,COG3290@1|root,COG2197@2|Bacteria,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity prhJ - - ko:K06375 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000 - - - GerE,HATPase_c,PAS,PAS_4,PAS_8,PAS_9,Response_reg PJD2_k127_975140_2 886293.Sinac_1688 1.261e-216 680.0 COG3033@1|root,COG3033@2|Bacteria,2J41D@203682|Planctomycetes 203682|Planctomycetes E Beta-eliminating lyase - - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase PJD2_k127_975140_14 673860.AciM339_0766 7.302e-59 209.0 COG1014@1|root,arCOG01603@2157|Archaea,2XVFR@28890|Euryarchaeota,3F2RB@33867|unclassified Euryarchaeota 28890|Euryarchaeota C Pyruvate ferredoxin/flavodoxin oxidoreductase porC - 1.2.7.1,1.2.7.7 ko:K00172,ko:K00189 ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R07160,R08034,R08566,R08567 RC00004,RC00250,RC02742,RC02833,RC02856 br01601,ko00000,ko00001,ko00002,ko01000 - - - POR PJD2_k127_975140_8 1232437.KL662020_gene770 2.313e-127 428.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,2MJ25@213118|Desulfobacterales 28221|Deltaproteobacteria E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4,Fer4_20,Fer4_9,Pyr_redox_2 PJD2_k127_975140_7 1121405.dsmv_1953 2.577e-133 436.0 COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales 28221|Deltaproteobacteria C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.1 ko:K00169 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N PJD2_k127_975140_10 1125863.JAFN01000001_gene2833 6.837e-110 362.0 COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria C PFAM Thiamine pyrophosphate - - 1.2.7.1,1.2.7.7 ko:K00170,ko:K00187 ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R07160,R08034,R08566,R08567 RC00004,RC00250,RC02742,RC02833,RC02856 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C PJD2_k127_975140_25 1336803.PHEL49_2496 8.008e-07 61.0 COG1361@1|root,COG2373@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein inlJ - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - CHU_C,DUF11,DUF5011,FctA,Gram_pos_anchor,MucBP,VWA_2 PJD2_k127_975140_15 1499967.BAYZ01000076_gene842 7.145e-55 216.0 COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria 2|Bacteria O Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_8 PJD2_k127_975140_17 1047013.AQSP01000123_gene1525 8.934e-49 192.0 COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria 2|Bacteria T Tetratricopeptide repeat - - - - - - - - - - - - Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 PJD2_k127_975140_12 1158345.JNLL01000001_gene1457 1.748e-71 253.0 COG2885@1|root,COG2885@2|Bacteria,2G4S4@200783|Aquificae 200783|Aquificae M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_YMGG,OmpA,TSP_3 PJD2_k127_975140_21 234267.Acid_3076 2.763e-40 160.0 COG2091@1|root,COG2091@2|Bacteria,3Y8HB@57723|Acidobacteria 57723|Acidobacteria H 4'-phosphopantetheinyl transferase superfamily - - - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS PJD2_k127_975140_0 204669.Acid345_0465 0.0 2209.0 COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria,2JHJH@204432|Acidobacteriia 204432|Acidobacteriia Q Ketoacyl-synthetase C-terminal extension - - - - - - - - - - - - ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt PJD2_k127_990852_0 575540.Isop_0365 3.851e-186 591.0 COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,2IZ46@203682|Planctomycetes 203682|Planctomycetes C Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - - - - - - - - - - Complex1_30kDa,Complex1_49kDa PJD2_k127_990852_1 575540.Isop_0364 1.887e-106 362.0 COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,2J033@203682|Planctomycetes 203682|Planctomycetes C NADH ubiquinone oxidoreductase, 20 Kd subunit - - - - - - - - - - - - Fer4,Oxidored_q6 PJD2_k127_990852_6 309807.SRU_2180 1.826e-06 61.0 COG0457@1|root,COG0457@2|Bacteria,4PEIW@976|Bacteroidetes,1FJ6Z@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - PJD2_k127_990852_4 913865.DOT_2964 3.507e-50 187.0 COG2318@1|root,COG2318@2|Bacteria,1V8MI@1239|Firmicutes 1239|Firmicutes S PFAM DinB family - - - - - - - - - - - - DinB PJD2_k127_990852_2 1501230.ET33_09000 5.004e-64 228.0 COG2227@1|root,COG2227@2|Bacteria,1VRKR@1239|Firmicutes,4HTNC@91061|Bacilli,26V78@186822|Paenibacillaceae 91061|Bacilli H Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_11 PJD2_k127_990852_3 1341151.ASZU01000015_gene2040 6.326e-64 248.0 COG3227@1|root,COG3227@2|Bacteria,1TSGU@1239|Firmicutes,4HC7W@91061|Bacilli,27CRY@186824|Thermoactinomycetaceae 91061|Bacilli E Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PepSY,Peptidase_M36 ## 2434 queries scanned ## Total time (seconds): 344.77515053749084 ## Rate: 7.06 q/s