## Thu Oct 17 11:08:49 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/PYH1_bin.65.fa -m mmseqs --itype genome -o PYH1_bin.65 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/PYH1_bin.65 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
PYH1_k127_1006933_1	2340.JV46_13050	1.462e-47	175.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1N12F@1224|Proteobacteria,1S7UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
PYH1_k127_1006933_0	2340.JV46_13040	5.873e-165	529.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J85H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
PYH1_k127_1039483_12	887898.HMPREF0551_0219	9.581e-89	297.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,1K22I@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
PYH1_k127_1039483_19	243365.CV_3050	1.594e-27	130.0	COG3038@1|root,COG3038@2|Bacteria,1RBP8@1224|Proteobacteria,2VQWK@28216|Betaproteobacteria,2KR9E@206351|Neisseriales	206351|Neisseriales	C	Prokaryotic cytochrome b561	cybB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
PYH1_k127_1039483_2	640081.Dsui_0052	1.24e-207	669.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,2KV4V@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
PYH1_k127_1039483_15	1038859.AXAU01000001_gene3742	1.97e-47	184.0	COG1917@1|root,COG1917@2|Bacteria,1RAGP@1224|Proteobacteria,2U5F3@28211|Alphaproteobacteria,3JYCW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
PYH1_k127_1039483_10	279714.FuraDRAFT_1484	3.996e-100	331.0	COG0625@1|root,COG0625@2|Bacteria,1RK1K@1224|Proteobacteria,2WEV9@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N_3
PYH1_k127_1039483_13	472759.Nhal_0303	1.35e-80	271.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,1S1HV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH1_k127_1039483_8	420324.KI912045_gene4644	6.127e-127	410.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,1JT5Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
PYH1_k127_1039483_22	349102.Rsph17025_0270	5.126e-11	66.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
PYH1_k127_1039483_7	1168034.FH5T_19015	3.607e-127	422.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1039483_21	211114.JOEF01000003_gene3145	1.227e-15	83.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4DYBS@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, crp family	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH1_k127_1039483_6	331678.Cphamn1_1855	2.11e-146	482.0	COG0493@1|root,COG0493@2|Bacteria,1FDFY@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2
PYH1_k127_1039483_20	1173026.Glo7428_3186	6.885e-26	113.0	COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
PYH1_k127_1039483_17	243365.CV_3231	4.192e-45	171.0	2C1BX@1|root,307EB@2|Bacteria,1MY9B@1224|Proteobacteria,2VRW7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1039483_3	864051.BurJ1DRAFT_1545	7.069e-195	616.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2VKXM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
PYH1_k127_1039483_9	1123504.JQKD01000005_gene4750	1.033e-102	342.0	COG1082@1|root,COG1082@2|Bacteria,1R87Z@1224|Proteobacteria,2VQ98@28216|Betaproteobacteria,4AITZ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
PYH1_k127_1039483_16	1123023.JIAI01000001_gene7780	1.169e-45	177.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
PYH1_k127_1039483_5	1121033.AUCF01000014_gene1306	2.775e-148	483.0	COG4948@1|root,COG4948@2|Bacteria,1MV2S@1224|Proteobacteria,2TTFB@28211|Alphaproteobacteria,2JVX4@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
PYH1_k127_1039483_11	1268622.AVS7_03518	3.165e-96	339.0	COG3181@1|root,COG3181@2|Bacteria,1N7C4@1224|Proteobacteria,2VHNI@28216|Betaproteobacteria,4A9W4@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_1039483_4	93220.LV28_08040	4.79e-181	592.0	COG0673@1|root,COG0673@2|Bacteria,1PYTN@1224|Proteobacteria,2VKKE@28216|Betaproteobacteria,1KGRJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
PYH1_k127_1039483_14	338969.Rfer_2484	1.791e-77	268.0	28NPW@1|root,2ZBPM@2|Bacteria,1RAMG@1224|Proteobacteria,2VQIF@28216|Betaproteobacteria,4AE6G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1039483_0	338969.Rfer_2485	4.685e-295	936.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,4AD7T@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3
PYH1_k127_1039483_1	1095769.CAHF01000005_gene1469	7.14e-294	915.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria	28216|Betaproteobacteria	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
PYH1_k127_1039483_23	67352.JODS01000004_gene5925	0.0002115	47.0	COG2021@1|root,COG2021@2|Bacteria,2I2Z2@201174|Actinobacteria	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
PYH1_k127_1046336_1	748247.AZKH_0630	4.942e-37	150.0	COG0741@1|root,COG0741@2|Bacteria,1RAP3@1224|Proteobacteria,2VQXG@28216|Betaproteobacteria,2KWVV@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
PYH1_k127_1046336_3	1392838.AWNM01000066_gene1344	2.959e-07	56.0	2ANGV@1|root,31DFK@2|Bacteria,1RJ5C@1224|Proteobacteria,2VSDR@28216|Betaproteobacteria,3T41B@506|Alcaligenaceae	28216|Betaproteobacteria	S	Histone H1-like nucleoprotein HC2	hctB	-	-	ko:K11275	-	-	-	-	ko00000,ko03036	-	-	-	HC2
PYH1_k127_1046336_2	357808.RoseRS_1993	1.388e-10	64.0	2DQJV@1|root,337C3@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
PYH1_k127_1046336_0	1000565.METUNv1_00215	2.1e-207	649.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,2KUGC@206389|Rhodocyclales	206389|Rhodocyclales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
PYH1_k127_1121817_6	1088721.NSU_3417	3.577e-29	132.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
PYH1_k127_1121817_4	1120983.KB894572_gene3265	7.391e-78	277.0	COG2267@1|root,COG2267@2|Bacteria,1PFU6@1224|Proteobacteria,2V8R5@28211|Alphaproteobacteria,1JPU4@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
PYH1_k127_1121817_1	76114.ebA6035	4.671e-154	503.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VK57@28216|Betaproteobacteria,2KV84@206389|Rhodocyclales	206389|Rhodocyclales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroA	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
PYH1_k127_1121817_5	314278.NB231_03085	4.85e-72	251.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1WYF0@135613|Chromatiales	135613|Chromatiales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
PYH1_k127_1121817_3	582744.Msip34_0969	2.29e-116	379.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2VH6D@28216|Betaproteobacteria,2KM8N@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
PYH1_k127_1121817_2	1411123.JQNH01000001_gene1723	7.817e-153	493.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	cytochrome P450	MA20_16830	-	-	-	-	-	-	-	-	-	-	-	p450
PYH1_k127_1121817_0	1163617.SCD_n01944	2.728e-209	662.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-binding domain protein	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
PYH1_k127_1147345_20	1007105.PT7_0669	3.612e-57	205.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2WGUW@28216|Betaproteobacteria,3T60B@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_1147345_6	1123024.AUII01000024_gene228	3.314e-112	380.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	ko:K21786	ko00333,ko01130,map00333,map01130	M00837,M00838	R11670	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25,Methyltransf_31
PYH1_k127_1147345_5	1449048.JQKU01000001_gene2296	3.291e-118	392.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,23724@1762|Mycobacteriaceae	201174|Actinobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
PYH1_k127_1147345_12	1205680.CAKO01000038_gene1931	4.046e-81	274.0	COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2U5B0@28211|Alphaproteobacteria,2JRTH@204441|Rhodospirillales	204441|Rhodospirillales	C	NADH dehydrogenase NAD(P)H nitroreductase	rutE	-	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
PYH1_k127_1147345_11	1449351.RISW2_00055	2.549e-82	303.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_1147345_17	1449351.RISW2_00060	3.108e-70	247.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_1147345_14	1280681.AUJZ01000013_gene1983	2.569e-78	272.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,4BW0I@830|Butyrivibrio	186801|Clostridia	E	ATPases associated with a variety of cellular activities	livF1	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_1147345_13	1449351.RISW2_00070	7.673e-80	273.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,4KKU7@93682|Roseivivax	28211|Alphaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_1147345_4	1449351.RISW2_00075	7.295e-123	400.0	COG4177@1|root,COG4177@2|Bacteria	2|Bacteria	E	L-phenylalanine transmembrane transporter activity	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH1_k127_1147345_8	1449351.RISW2_00080	2.127e-91	309.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_1147345_2	1449351.RISW2_00085	1.635e-142	489.0	COG0683@1|root,COG0683@2|Bacteria,1RBGU@1224|Proteobacteria,2U6VH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_1147345_1	1207063.P24_09316	5.707e-227	715.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,2JP99@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_1147345_15	1366050.N234_34665	5.422e-78	271.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,2VHM0@28216|Betaproteobacteria,1K3NS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	phenazine biosynthesis protein PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
PYH1_k127_1147345_10	1100720.ALKN01000045_gene465	1.285e-83	296.0	COG4927@1|root,COG4927@2|Bacteria,1NKHP@1224|Proteobacteria,2VKAB@28216|Betaproteobacteria,4AAI6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	ko:K19200	ko00311,ko01100,ko01130,map00311,map01100,map01130	-	-	-	ko00000,ko00001,ko01002	-	-	-	AAT
PYH1_k127_1147345_18	1123366.TH3_19662	3.212e-64	248.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2TU6M@28211|Alphaproteobacteria,2JRRQ@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH1_k127_1147345_0	1205680.CAKO01000037_gene1244	1.08e-286	891.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2JQP4@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase B/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydantoinase_B
PYH1_k127_1147345_9	1380394.JADL01000016_gene409	3.06e-91	310.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2TSWT@28211|Alphaproteobacteria,2JSPC@204441|Rhodospirillales	204441|Rhodospirillales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_1147345_21	748247.AZKH_p0370	1.829e-38	162.0	COG3218@1|root,COG3218@2|Bacteria,1NCG2@1224|Proteobacteria,2VWSK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
PYH1_k127_1147345_19	614083.AWQR01000025_gene3665	6.298e-63	237.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,4AAHD@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
PYH1_k127_1147345_7	1163617.SCD_n01514	4.718e-106	368.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Abc transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
PYH1_k127_1147345_3	1163617.SCD_n01513	6.499e-129	422.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
PYH1_k127_1147345_16	338969.Rfer_4072	5.523e-72	247.0	COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,2VSTC@28216|Betaproteobacteria,4AHVS@80864|Comamonadaceae	28216|Betaproteobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
PYH1_k127_1210880_9	1123073.KB899242_gene1488	2.692e-101	334.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,1RQZZ@1236|Gammaproteobacteria,1X6IV@135614|Xanthomonadales	135614|Xanthomonadales	T	response regulator	-	-	-	ko:K02483,ko:K07661,ko:K18073	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00446,M00654,M00721,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH1_k127_1210880_16	394.NGR_c30280	8.583e-13	78.0	COG3678@1|root,COG3678@2|Bacteria,1N0SB@1224|Proteobacteria,2UDWY@28211|Alphaproteobacteria,4BAUZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	NPTU	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
PYH1_k127_1210880_14	1123392.AQWL01000002_gene1903	1.328e-35	140.0	COG1416@1|root,COG1416@2|Bacteria,1RE8C@1224|Proteobacteria,2VV8B@28216|Betaproteobacteria,1KT2D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
PYH1_k127_1210880_15	1163617.SCD_n01636	9.63e-24	108.0	COG1416@1|root,COG1416@2|Bacteria,1RE8C@1224|Proteobacteria,2VV8B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
PYH1_k127_1210880_8	748280.NH8B_2256	1.36e-103	364.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,2KQ7Q@206351|Neisseriales	206351|Neisseriales	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
PYH1_k127_1210880_4	1266925.JHVX01000004_gene1141	2.027e-150	488.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria,372K1@32003|Nitrosomonadales	28216|Betaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
PYH1_k127_1210880_12	1265502.KB905930_gene1414	1.652e-72	257.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2WA1J@28216|Betaproteobacteria,4AFHN@80864|Comamonadaceae	28216|Betaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
PYH1_k127_1210880_13	1038859.AXAU01000020_gene5398	3.773e-61	219.0	COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2TTXF@28211|Alphaproteobacteria,3JRB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
PYH1_k127_1210880_5	1038859.AXAU01000016_gene6832	1.746e-140	452.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3JRVC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
PYH1_k127_1210880_0	580332.Slit_0865	7.44e-188	596.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,2VM57@28216|Betaproteobacteria	28216|Betaproteobacteria	P	NhaP-type Na H and K H antiporters with a unique C-terminal domain	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	CorC_HlyC,Na_H_Exchanger,TrkA_C
PYH1_k127_1210880_10	1038859.AXAU01000005_gene5188	3.463e-94	316.0	COG1028@1|root,COG1028@2|Bacteria,1MVA5@1224|Proteobacteria,2U2EZ@28211|Alphaproteobacteria,3JWQS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_21425	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
PYH1_k127_1210880_6	485913.Krac_9502	1.653e-117	388.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	fadB5	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
PYH1_k127_1210880_3	1502850.FG91_01336	2.73e-155	500.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2K0AI@204457|Sphingomonadales	204457|Sphingomonadales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH1_k127_1210880_1	391038.Bphy_3709	4.093e-175	559.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,2VMYG@28216|Betaproteobacteria,1K3ES@119060|Burkholderiaceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH1_k127_1210880_2	264198.Reut_B5858	9.52e-174	554.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,2VNEP@28216|Betaproteobacteria,1K3V4@119060|Burkholderiaceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH1_k127_1210880_7	269482.Bcep1808_0286	5.435e-111	363.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VIKP@28216|Betaproteobacteria,1K47S@119060|Burkholderiaceae	28216|Betaproteobacteria	V	abc transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH1_k127_1210880_11	1071679.BG57_11090	1.271e-83	281.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,2VIYG@28216|Betaproteobacteria,1K520@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
PYH1_k127_1212874_1	935261.JAGL01000006_gene2275	1.148e-47	196.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria,43RQ1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
PYH1_k127_1212874_0	1123072.AUDH01000011_gene3621	2.85e-277	865.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,2JPMB@204441|Rhodospirillales	204441|Rhodospirillales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
PYH1_k127_1223302_1	335543.Sfum_2673	8.16e-49	181.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
PYH1_k127_1223302_0	404589.Anae109_0440	8.577e-71	252.0	COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria,2Z1WI@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_1251390_0	640081.Dsui_0842	5.537e-111	379.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2VH2P@28216|Betaproteobacteria,2KUY7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH1_k127_1251390_1	1304883.KI912532_gene937	3.273e-92	308.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2VH2P@28216|Betaproteobacteria,2KUY7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH1_k127_1271437_3	1040989.AWZU01000012_gene1396	3.066e-115	384.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TT4A@28211|Alphaproteobacteria,3JU8B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH1_k127_1271437_1	742159.HMPREF0004_5390	5.831e-175	560.0	COG1960@1|root,COG1960@2|Bacteria,1MX17@1224|Proteobacteria,2VM2C@28216|Betaproteobacteria,3T6AI@506|Alcaligenaceae	28216|Betaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_1271437_11	1230476.C207_01742	1.738e-16	85.0	COG3255@1|root,COG3255@2|Bacteria,1RG3A@1224|Proteobacteria,2U8E5@28211|Alphaproteobacteria,3JYTW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1271437_2	398525.KB900701_gene5786	6.962e-118	391.0	COG0596@1|root,COG0596@2|Bacteria,1NUT9@1224|Proteobacteria,2TVMS@28211|Alphaproteobacteria,3JUAG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
PYH1_k127_1271437_5	234621.RER_08370	4.406e-98	332.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4FZ1H@85025|Nocardiaceae	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	mmsB2	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
PYH1_k127_1271437_7	1366050.N234_22440	2.895e-87	314.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP82@28216|Betaproteobacteria,1KD4A@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_1271437_4	1120983.KB894572_gene3112	1.373e-113	398.0	COG0365@1|root,COG0654@1|root,COG0365@2|Bacteria,COG0654@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,1JNCA@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,FAD_binding_3
PYH1_k127_1271437_10	420324.KI911952_gene3300	2.839e-39	168.0	COG0457@1|root,COG0457@2|Bacteria,1N6TJ@1224|Proteobacteria,2UG5W@28211|Alphaproteobacteria,1JYPC@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
PYH1_k127_1271437_0	420324.KI911952_gene3298	2.639e-222	701.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,1JRF3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1271437_6	296591.Bpro_0189	1.754e-87	291.0	COG3791@1|root,COG3791@2|Bacteria,1RFBP@1224|Proteobacteria,2VQN8@28216|Betaproteobacteria,4AE1T@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
PYH1_k127_1271437_9	1276756.AUEX01000030_gene200	9.997e-73	251.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,2VQ0V@28216|Betaproteobacteria,4AGUW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PYH1_k127_1271437_8	795666.MW7_2046	2.455e-79	275.0	COG3181@1|root,COG3181@2|Bacteria,1R8DS@1224|Proteobacteria,2W1MT@28216|Betaproteobacteria,1K4EH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_1273537_4	365044.Pnap_2131	5.793e-109	355.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,4ABCD@80864|Comamonadaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
PYH1_k127_1273537_3	1095769.CAHF01000006_gene1963	9.347e-141	453.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2VI6W@28216|Betaproteobacteria,47253@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
PYH1_k127_1273537_0	522306.CAP2UW1_2342	3.109e-246	788.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,1KQCN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
PYH1_k127_1273537_1	765420.OSCT_2013	1.583e-182	601.0	COG0318@1|root,COG0318@2|Bacteria,2G5SX@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_1273537_2	2340.JV46_13030	2.171e-141	456.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,1S7ID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
PYH1_k127_1273537_5	2340.JV46_13040	1.914e-07	53.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J85H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
PYH1_k127_1278557_3	1454004.AW11_00272	6.819e-60	211.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,1KPPG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Single-stranded-DNA-specific exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
PYH1_k127_1278557_2	296591.Bpro_3676	4.51e-161	521.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,4A9SZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
PYH1_k127_1278557_4	414684.RC1_1514	7.944e-47	180.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
PYH1_k127_1278557_5	47763.JNZA01000009_gene5503	1.838e-29	132.0	COG2164@1|root,COG2164@2|Bacteria,2II7B@201174|Actinobacteria	201174|Actinobacteria	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
PYH1_k127_1278557_6	887898.HMPREF0551_1228	3.248e-07	60.0	2EH9R@1|root,33B1M@2|Bacteria,1NH7Y@1224|Proteobacteria,2VXYE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
PYH1_k127_1278557_1	1121035.AUCH01000001_gene1949	7.769e-167	531.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,2KUA1@206389|Rhodocyclales	206389|Rhodocyclales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
PYH1_k127_1278557_0	1163617.SCD_n01828	1.008e-201	655.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
PYH1_k127_1278557_7	1097668.BYI23_A004400	0.0007658	47.0	COG3133@1|root,COG3133@2|Bacteria,1RK6D@1224|Proteobacteria,2VU04@28216|Betaproteobacteria,1K4WT@119060|Burkholderiaceae	28216|Betaproteobacteria	M	17 kDa surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
PYH1_k127_1303648_1	1131814.JAFO01000001_gene3088	2.415e-138	451.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria,3F0TD@335928|Xanthobacteraceae	28211|Alphaproteobacteria	J	Amidase	MA20_19360	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH1_k127_1303648_2	1265502.KB905930_gene1481	4.538e-72	261.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,4ACNB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the MtfA family	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
PYH1_k127_1303648_3	640081.Dsui_2817	1.248e-70	254.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,2KUCN@206389|Rhodocyclales	206389|Rhodocyclales	EG	Solute carrier family 35	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_1303648_0	522306.CAP2UW1_1062	6.675e-201	639.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,1KPSA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
PYH1_k127_1312202_0	1380394.JADL01000009_gene3119	2.368e-168	551.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2JQAX@204441|Rhodospirillales	204441|Rhodospirillales	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PYH1_k127_1312202_1	522306.CAP2UW1_0299	3.281e-75	284.0	COG2202@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KQH8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
PYH1_k127_1312202_2	314345.SPV1_12290	5.859e-07	51.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria	1224|Proteobacteria	BQ	Including yeast histone deacetylase and acetoin utilization protein	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
PYH1_k127_1322739_1	85643.Tmz1t_3789	5.27e-108	361.0	COG3206@1|root,COG3944@1|root,COG3206@2|Bacteria,COG3944@2|Bacteria,1QUY4@1224|Proteobacteria,2VMTT@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
PYH1_k127_1322739_0	395494.Galf_1266	1.104e-174	563.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VJBU@28216|Betaproteobacteria	28216|Betaproteobacteria	M	polysaccharide export protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
PYH1_k127_1325638_12	1266925.JHVX01000009_gene72	2.989e-36	147.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,37258@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
PYH1_k127_1325638_1	1454004.AW11_01897	7.229e-217	690.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria,1KPUU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
PYH1_k127_1325638_11	323848.Nmul_A1866	1.453e-46	172.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,37338@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
PYH1_k127_1325638_7	765910.MARPU_09040	1.008e-83	287.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1WW93@135613|Chromatiales	135613|Chromatiales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PYH1_k127_1325638_8	640081.Dsui_2726	7.486e-78	264.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,2KW8D@206389|Rhodocyclales	206389|Rhodocyclales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
PYH1_k127_1325638_5	1158292.JPOE01000005_gene460	5.988e-91	324.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,1KJBJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
PYH1_k127_1325638_2	1163617.SCD_n01478	6.027e-205	655.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
PYH1_k127_1325638_9	1304883.KI912532_gene2217	8.061e-78	268.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,2KVFM@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
PYH1_k127_1325638_6	76114.ebA6128	3.193e-86	289.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,2KUMD@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the SUA5 family	yrdC	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
PYH1_k127_1325638_4	29581.BW37_01808	4.517e-104	349.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,47249@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_1325638_10	331869.BAL199_03129	1.722e-57	205.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,4BQC2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
PYH1_k127_1325638_3	1095769.CAHF01000007_gene1683	1.646e-108	356.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2VHU8@28216|Betaproteobacteria,47273@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG3	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
PYH1_k127_1325638_0	323848.Nmul_A1150	0.0	1565.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1PV5D@1224|Proteobacteria,2WB3J@28216|Betaproteobacteria,37281@32003|Nitrosomonadales	28216|Betaproteobacteria	CEH	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
PYH1_k127_1326560_6	1198452.Jab_2c21390	1.501e-79	273.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Haemagg_act
PYH1_k127_1326560_12	62928.azo3390	1.574e-55	201.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,2KWG3@206389|Rhodocyclales	206389|Rhodocyclales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
PYH1_k127_1326560_1	1288494.EBAPG3_30060	7.518e-168	532.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,372HG@32003|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
PYH1_k127_1326560_2	305700.B447_16081	3.707e-104	341.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,2KUIJ@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
PYH1_k127_1326560_10	1123487.KB892835_gene3664	1.619e-62	218.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,2KW6N@206389|Rhodocyclales	206389|Rhodocyclales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
PYH1_k127_1326560_13	323848.Nmul_A0789	1.083e-52	188.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,37389@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
PYH1_k127_1326560_23	338969.Rfer_4221	6.153e-13	68.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,2VXPQ@28216|Betaproteobacteria,4AFV9@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
PYH1_k127_1326560_19	1304883.KI912532_gene455	1.487e-29	134.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,2KWY1@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
PYH1_k127_1326560_0	522306.CAP2UW1_3473	4.822e-233	728.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,1KPR8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
PYH1_k127_1326560_14	887898.HMPREF0551_1888	2.912e-52	189.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,1K75Y@119060|Burkholderiaceae	28216|Betaproteobacteria	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
PYH1_k127_1326560_22	497321.C664_09215	1.867e-17	84.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,2KX85@206389|Rhodocyclales	206389|Rhodocyclales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
PYH1_k127_1326560_5	1288494.EBAPG3_29970	6.955e-84	280.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,3723A@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
PYH1_k127_1326560_17	522306.CAP2UW1_3477	2.966e-41	154.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,1KQ25@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
PYH1_k127_1326560_7	305700.B447_16031	1.452e-77	265.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,2KW6K@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
PYH1_k127_1326560_11	1218084.BBJK01000103_gene6482	3.567e-62	216.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,1K77S@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
PYH1_k127_1326560_18	1485544.JQKP01000001_gene1123	6.653e-35	137.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,44VZE@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
PYH1_k127_1326560_4	323848.Nmul_A0779	9.642e-89	300.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,372JB@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
PYH1_k127_1326560_15	159087.Daro_0330	9.286e-51	181.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria,2KWPF@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
PYH1_k127_1326560_9	395494.Galf_0568	1.287e-63	220.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2VR2N@28216|Betaproteobacteria,44VU6@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
PYH1_k127_1326560_20	987059.RBXJA2T_02160	8.884e-29	120.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,1KMEY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
PYH1_k127_1326560_21	159087.Daro_0327	8.734e-20	89.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2VVNT@28216|Betaproteobacteria,2KXD6@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
PYH1_k127_1326560_8	1123367.C666_00460	2.63e-70	239.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,2KW4S@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
PYH1_k127_1326560_3	580332.Slit_0773	2.933e-98	329.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,44VEP@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
PYH1_k127_1326560_16	748247.AZKH_3994	1.179e-47	172.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2VSE6@28216|Betaproteobacteria,2KWKB@206389|Rhodocyclales	206389|Rhodocyclales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
PYH1_k127_1342790_0	1380394.JADL01000004_gene6059	9.99e-138	455.0	COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2TTHE@28211|Alphaproteobacteria,2JQ2E@204441|Rhodospirillales	204441|Rhodospirillales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	POR
PYH1_k127_1342790_1	1380394.JADL01000001_gene2023	5.388e-134	458.0	COG3435@1|root,COG3435@2|Bacteria,1MVJP@1224|Proteobacteria,2TUUS@28211|Alphaproteobacteria,2JS7H@204441|Rhodospirillales	204441|Rhodospirillales	Q	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH1_k127_1342790_2	1095769.CAHF01000011_gene2648	6.566e-82	298.0	COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2VNRV@28216|Betaproteobacteria	28216|Betaproteobacteria	I	esterase	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,COesterase
PYH1_k127_1342790_3	1232437.KL661978_gene3875	1.644e-73	252.0	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,42QTZ@68525|delta/epsilon subdivisions,2WMV1@28221|Deltaproteobacteria,2MJRM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PYH1_k127_1342815_0	1265502.KB905964_gene1374	1.521e-255	799.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
PYH1_k127_1342815_1	1100720.ALKN01000007_gene3022	3.248e-20	90.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
PYH1_k127_138179_0	670292.JH26_11815	2.979e-127	416.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PYH1_k127_138179_1	1079460.ATTQ01000003_gene1593	1.092e-43	179.0	2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,2U77A@28211|Alphaproteobacteria,4BMZR@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1392161_0	667632.KB890164_gene1842	0.0	1244.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,1K532@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
PYH1_k127_1392161_9	887898.HMPREF0551_0785	1.222e-169	552.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,1K1V0@119060|Burkholderiaceae	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
PYH1_k127_1392161_6	640081.Dsui_2219	6.035e-195	617.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,2KUQ1@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
PYH1_k127_1392161_20	1121106.JQKB01000005_gene2143	4.071e-82	289.0	COG0697@1|root,COG0697@2|Bacteria,1MX07@1224|Proteobacteria,2TQNT@28211|Alphaproteobacteria,2JRSM@204441|Rhodospirillales	204441|Rhodospirillales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_1392161_12	266265.Bxe_A2809	3.327e-131	443.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2VHQX@28216|Betaproteobacteria,1K0KZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM AFG1-family ATPase	yhcM	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
PYH1_k127_1392161_15	1304883.KI912532_gene3006	1.06e-120	398.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,2KU9K@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_1392161_3	85643.Tmz1t_1614	3.438e-292	924.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VI3T@28216|Betaproteobacteria,2KV9F@206389|Rhodocyclales	206389|Rhodocyclales	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	prpE	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
PYH1_k127_1392161_27	864051.BurJ1DRAFT_2450	5.148e-34	145.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2VRBU@28216|Betaproteobacteria,1KKW1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
PYH1_k127_1392161_22	864051.BurJ1DRAFT_2043	2.069e-46	179.0	COG3193@1|root,COG3193@2|Bacteria,1RH9E@1224|Proteobacteria,2VT15@28216|Betaproteobacteria,1KMD6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
PYH1_k127_1392161_24	1336243.JAEA01000005_gene1448	4.064e-44	177.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2UBDQ@28211|Alphaproteobacteria,1JZ95@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
PYH1_k127_1392161_10	1121861.KB899919_gene2714	5.034e-161	518.0	COG1804@1|root,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2TRIZ@28211|Alphaproteobacteria,2JQ9Z@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3,HMGL-like
PYH1_k127_1392161_13	1123504.JQKD01000008_gene5347	1.499e-121	396.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VHK4@28216|Betaproteobacteria,4AJ7S@80864|Comamonadaceae	28216|Betaproteobacteria	E	Pyruvate carboxyltransferase	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
PYH1_k127_1392161_21	1121033.AUCF01000026_gene2992	2.894e-76	286.0	COG2807@1|root,COG2807@2|Bacteria,1QU85@1224|Proteobacteria,2TXRC@28211|Alphaproteobacteria,2JZ2E@204441|Rhodospirillales	204441|Rhodospirillales	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_1392161_5	1247726.MIM_c26580	7.615e-256	799.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,3T1SC@506|Alcaligenaceae	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
PYH1_k127_1392161_2	1163617.SCD_n01957	0.0	1052.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
PYH1_k127_1392161_31	748280.NH8B_3992	2.085e-17	83.0	2DNR5@1|root,32YQH@2|Bacteria,1NBXJ@1224|Proteobacteria,2VW7K@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1392161_1	296591.Bpro_4149	0.0	1208.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,4AAXQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
PYH1_k127_1392161_23	296591.Bpro_4150	2.743e-46	169.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,4AEF6@80864|Comamonadaceae	28216|Betaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PYH1_k127_1392161_7	296591.Bpro_4151	3.284e-180	592.0	COG2176@1|root,COG5002@1|root,COG2176@2|Bacteria,COG5002@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,4AD1W@80864|Comamonadaceae	28216|Betaproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
PYH1_k127_1392161_14	296591.Bpro_4152	4.69e-121	404.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,4AC6C@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
PYH1_k127_1392161_28	580332.Slit_2491	4.219e-32	127.0	COG4327@1|root,COG4327@2|Bacteria,1PDE2@1224|Proteobacteria,2VW4R@28216|Betaproteobacteria,44WJQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
PYH1_k127_1392161_4	296591.Bpro_4144	1.649e-282	883.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,4AA9Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP_1	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
PYH1_k127_1392161_26	640081.Dsui_2008	4.311e-38	151.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VR7H@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
PYH1_k127_1392161_30	1123392.AQWL01000002_gene1810	4.971e-18	87.0	2EJDA@1|root,33D4B@2|Bacteria,1NJG2@1224|Proteobacteria,2VXQP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1392161_32	420662.Mpe_A0549	7.053e-16	86.0	2ETEI@1|root,33KYE@2|Bacteria,1NJKD@1224|Proteobacteria,2W43N@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1392161_8	640081.Dsui_1809	5.226e-180	578.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,2KUDK@206389|Rhodocyclales	206389|Rhodocyclales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
PYH1_k127_1392161_25	153948.NAL212_1617	4.272e-40	152.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,373BM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
PYH1_k127_1392161_19	1163617.SCD_n01512	1.167e-84	285.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
PYH1_k127_1392161_16	296591.Bpro_2272	1.941e-119	392.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,4A9W3@80864|Comamonadaceae	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
PYH1_k127_1392161_17	859657.RPSI07_2178	8.717e-108	369.0	COG1116@1|root,COG1116@2|Bacteria,1N7FP@1224|Proteobacteria,2VHGX@28216|Betaproteobacteria,1KGMZ@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
PYH1_k127_1392161_11	1071679.BG57_15300	1.963e-131	423.0	COG0600@1|root,COG0600@2|Bacteria,1MVD2@1224|Proteobacteria,2VI9N@28216|Betaproteobacteria,1K17T@119060|Burkholderiaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
PYH1_k127_1392161_18	596154.Alide2_3931	6.981e-86	306.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_1392161_34	1120977.JHUX01000003_gene2083	1.624e-06	53.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria,3NQGN@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1400050_4	565045.NOR51B_1984	1.225e-13	79.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1J4XE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
PYH1_k127_1400050_0	398527.Bphyt_6755	0.0	1203.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VHCG@28216|Betaproteobacteria,1K1HS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
PYH1_k127_1400050_2	640081.Dsui_3156	7.304e-47	185.0	COG0730@1|root,COG0730@2|Bacteria,1RKNK@1224|Proteobacteria,2VY8V@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH1_k127_1400050_3	9612.ENSCAFP00000020477	9.36e-22	110.0	COG0515@1|root,KOG0192@2759|Eukaryota,39SGA@33154|Opisthokonta,3BFNI@33208|Metazoa,3CZ58@33213|Bilateria,483MU@7711|Chordata,48XFT@7742|Vertebrata,3JCGK@40674|Mammalia,3EINR@33554|Carnivora	33208|Metazoa	T	Ankyrin repeat and kinase domain containing 1	ANKK1	-	2.7.11.1	ko:K16289	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,Pkinase,Pkinase_Tyr
PYH1_k127_1400050_1	859657.RPSI07_1012	2.735e-63	224.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VP68@28216|Betaproteobacteria,1K1EY@119060|Burkholderiaceae	28216|Betaproteobacteria	C	luciferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
PYH1_k127_145403_7	1192034.CAP_2678	1.803e-10	62.0	COG2755@1|root,COG2755@2|Bacteria,1N7J4@1224|Proteobacteria	1224|Proteobacteria	E	Stress responsive alpha-beta barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
PYH1_k127_145403_4	1123487.KB892835_gene3645	1.578e-39	159.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2VSGE@28216|Betaproteobacteria,2KWRG@206389|Rhodocyclales	206389|Rhodocyclales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
PYH1_k127_145403_0	1121004.ATVC01000003_gene524	2.584e-138	443.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,2KPKG@206351|Neisseriales	206351|Neisseriales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
PYH1_k127_145403_5	1485544.JQKP01000001_gene1112	3.192e-32	137.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,44VXD@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
PYH1_k127_145403_2	360910.BAV0026	7.878e-90	302.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2VHS6@28216|Betaproteobacteria,3T25A@506|Alcaligenaceae	28216|Betaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
PYH1_k127_145403_1	640081.Dsui_0359	1.058e-90	303.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2VJ3V@28216|Betaproteobacteria,2KV3R@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
PYH1_k127_145403_3	1304883.KI912532_gene477	2.585e-53	188.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2VSDQ@28216|Betaproteobacteria,2KWNB@206389|Rhodocyclales	206389|Rhodocyclales	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
PYH1_k127_145403_6	1200567.JNKD01000071_gene1187	7.891e-17	79.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1Y3XP@135624|Aeromonadales	135624|Aeromonadales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
PYH1_k127_1480476_0	748247.AZKH_2859	2.774e-264	824.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,2KV38@206389|Rhodocyclales	206389|Rhodocyclales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
PYH1_k127_1480476_4	76114.ebA5443	5.966e-108	360.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria,2KUN8@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PYH1_k127_1480476_5	522306.CAP2UW1_1528	3.081e-71	250.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,1KQP9@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PYH1_k127_1480476_7	1235457.C404_15250	1.702e-31	132.0	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2VTX8@28216|Betaproteobacteria,1K7S5@119060|Burkholderiaceae	28216|Betaproteobacteria	P	rieske 2fe-2s	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
PYH1_k127_1480476_3	1266925.JHVX01000004_gene1115	1.359e-121	399.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,3727I@32003|Nitrosomonadales	28216|Betaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
PYH1_k127_1480476_6	522306.CAP2UW1_1532	1.212e-64	229.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,1KPZY@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
PYH1_k127_1480476_10	748247.AZKH_2854	7.517e-24	107.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,2VUIG@28216|Betaproteobacteria,2KX2U@206389|Rhodocyclales	206389|Rhodocyclales	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
PYH1_k127_1480476_9	85643.Tmz1t_2430	6.556e-26	108.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,2KX6E@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
PYH1_k127_1480476_2	1120999.JONM01000007_gene1733	4.825e-130	426.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,2KPM5@206351|Neisseriales	206351|Neisseriales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
PYH1_k127_1480476_1	522306.CAP2UW1_1536	3.582e-130	441.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,1KPNJ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
PYH1_k127_1480476_8	795666.MW7_1406	2.476e-28	117.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,1K35C@119060|Burkholderiaceae	28216|Betaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
PYH1_k127_1518247_1	1123368.AUIS01000016_gene2550	6.995e-25	109.0	2DM2X@1|root,31HF3@2|Bacteria,1RIYM@1224|Proteobacteria,1SFV4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1518247_0	1123368.AUIS01000016_gene2551	1.286e-228	719.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,2NCBG@225057|Acidithiobacillales	1236|Gammaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
PYH1_k127_1523429_10	272560.BPSL3125	7.021e-103	339.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,1K0VU@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
PYH1_k127_1523429_0	977880.RALTA_A1802	7.924e-185	585.0	COG0683@1|root,COG0683@2|Bacteria,1N1MX@1224|Proteobacteria,2VJMT@28216|Betaproteobacteria,1KGRT@119060|Burkholderiaceae	28216|Betaproteobacteria	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_1523429_8	1121920.AUAU01000008_gene1546	3.465e-111	364.0	COG0411@1|root,COG0411@2|Bacteria	2|Bacteria	E	ABC transporter	MA20_23480	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_1523429_9	1110502.TMO_2010	2.623e-109	364.0	COG0410@1|root,COG0410@2|Bacteria,1MW9R@1224|Proteobacteria,2TQTA@28211|Alphaproteobacteria,2JQYI@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_1523429_4	883078.HMPREF9695_01003	1.535e-122	412.0	COG0559@1|root,COG0559@2|Bacteria,1MVZ5@1224|Proteobacteria,2TRD6@28211|Alphaproteobacteria,3JU4K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	MA20_23490	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_1523429_2	1123504.JQKD01000005_gene4784	4.751e-130	440.0	COG4177@1|root,COG4177@2|Bacteria,1MZDJ@1224|Proteobacteria,2VJSE@28216|Betaproteobacteria,4AAFD@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_1523429_3	1265502.KB905938_gene2431	3.469e-123	418.0	COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,2VKCZ@28216|Betaproteobacteria,4AC2B@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_1523429_11	305700.B447_12854	1.031e-102	345.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,2KUWA@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
PYH1_k127_1523429_17	640081.Dsui_1423	2.696e-29	120.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,2KWT9@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
PYH1_k127_1523429_18	640081.Dsui_1422	5.632e-25	105.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,2KX8N@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
PYH1_k127_1523429_15	522306.CAP2UW1_4041	1.197e-44	168.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,1KQ3Q@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	FG	Nucleotide transport and metabolism Carbohydrate transport and metabolism General function prediction only	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
PYH1_k127_1523429_16	1120999.JONM01000010_gene4120	1.167e-34	138.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,2KRIM@206351|Neisseriales	206351|Neisseriales	E	Psort location Cytoplasmic, score	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
PYH1_k127_1523429_14	1112217.PPL19_16285	1.9e-58	205.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_5014	PRA-CH,PRA-PH
PYH1_k127_1523429_6	323848.Nmul_A0814	3.321e-118	385.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,3724H@32003|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
PYH1_k127_1523429_7	1000565.METUNv1_02435	5.939e-117	380.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,2KUM6@206389|Rhodocyclales	206389|Rhodocyclales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
PYH1_k127_1523429_13	748247.AZKH_0758	4.575e-86	288.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,2KUCS@206389|Rhodocyclales	206389|Rhodocyclales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
PYH1_k127_1523429_12	1144319.PMI16_02341	5.411e-97	329.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,473JG@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
PYH1_k127_1523429_5	266264.Rmet_3247	2.667e-120	396.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,1K1VS@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH1_k127_1523429_1	522306.CAP2UW1_4033	5.64e-151	484.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,1KPQM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
PYH1_k127_1526589_3	748247.AZKH_4266	2.079e-118	399.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,2KU6T@206389|Rhodocyclales	206389|Rhodocyclales	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
PYH1_k127_1526589_2	640081.Dsui_0325	7.399e-202	635.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VMHS@28216|Betaproteobacteria,2KUQ2@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the thiolase family	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH1_k127_1526589_0	522306.CAP2UW1_3464	6.768e-317	1002.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
PYH1_k127_1526589_6	76114.c1A220	3.282e-62	222.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VJQ5@28216|Betaproteobacteria,2KV0G@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PYH1_k127_1526589_1	323848.Nmul_A0682	1.992e-237	748.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,372IA@32003|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PYH1_k127_1526589_5	640081.Dsui_0128	2.023e-87	299.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,2KUX8@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S11 family	pbp	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
PYH1_k127_1526589_4	105559.Nwat_1070	6.856e-93	328.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,1WVVH@135613|Chromatiales	135613|Chromatiales	S	Methyltransferase	-	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
PYH1_k127_1537244_8	1121351.AUAP01000001_gene650	8.07e-59	220.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,2KPIR@206351|Neisseriales	206351|Neisseriales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
PYH1_k127_1537244_5	1123393.KB891317_gene2337	1.1e-81	285.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2VQ52@28216|Betaproteobacteria,1KS78@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
PYH1_k127_1537244_6	243365.CV_3306	2.386e-64	234.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria,2KQV8@206351|Neisseriales	206351|Neisseriales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
PYH1_k127_1537244_1	402626.Rpic_2967	2.976e-164	535.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,1K159@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
PYH1_k127_1537244_9	640081.Dsui_3338	4.259e-51	195.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,2KWI7@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PYH1_k127_1537244_4	1382304.JNIL01000001_gene1129	2.496e-121	402.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes	1239|Firmicutes	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
PYH1_k127_1537244_3	420662.Mpe_A2504	1.192e-127	419.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2VHCH@28216|Betaproteobacteria,1KJVM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
PYH1_k127_1537244_7	107635.AZUO01000001_gene1584	3.184e-62	243.0	COG0500@1|root,COG2226@2|Bacteria,1PVPS@1224|Proteobacteria,2TREE@28211|Alphaproteobacteria,370VV@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
PYH1_k127_1537244_2	864051.BurJ1DRAFT_3296	2.106e-154	497.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria	1224|Proteobacteria	S	Beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
PYH1_k127_1537244_10	1283300.ATXB01000001_gene285	2.516e-20	94.0	COG4190@1|root,COG4190@2|Bacteria,1N98Y@1224|Proteobacteria,1SD1M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
PYH1_k127_1537244_0	472759.Nhal_0770	7.793e-273	853.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1WWS1@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
PYH1_k127_1544921_4	76114.ebA4628	6.368e-94	332.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VK3W@28216|Betaproteobacteria,2KUJD@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
PYH1_k127_1544921_2	365046.Rta_16670	4.767e-95	320.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM3I@28216|Betaproteobacteria,4AB0D@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_1544921_7	765420.OSCT_1961	1.304e-40	173.0	COG1279@1|root,COG1279@2|Bacteria	2|Bacteria	S	arginine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	LysE
PYH1_k127_1544921_8	1121920.AUAU01000017_gene1225	1.254e-27	117.0	COG0748@1|root,COG0748@2|Bacteria,3Y2Q3@57723|Acidobacteria	57723|Acidobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Pyrid_oxidase_2
PYH1_k127_1544921_0	265072.Mfla_2095	1.239e-177	567.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,2KKB0@206350|Nitrosomonadales	206350|Nitrosomonadales	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
PYH1_k127_1544921_5	1348657.M622_16420	1.841e-85	289.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,2KUEU@206389|Rhodocyclales	206389|Rhodocyclales	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
PYH1_k127_1544921_3	640081.Dsui_2821	4.829e-94	343.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,2WEJI@28216|Betaproteobacteria,2KUP5@206389|Rhodocyclales	206389|Rhodocyclales	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
PYH1_k127_1544921_6	580332.Slit_1397	1.824e-51	188.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2VSHR@28216|Betaproteobacteria,44VXR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
PYH1_k127_1544921_1	1163617.SCD_n01103	1.253e-132	437.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
PYH1_k127_154669_6	1244869.H261_17608	3.778e-08	56.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,2JR4Z@204441|Rhodospirillales	204441|Rhodospirillales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
PYH1_k127_154669_4	34506.g5839	5.181e-23	115.0	COG1282@1|root,2QQ0A@2759|Eukaryota,38CB0@33154|Opisthokonta,3BDQK@33208|Metazoa,3CWZ6@33213|Bilateria,40AUM@6231|Nematoda,1KYC7@119089|Chromadorea,40YPW@6236|Rhabditida	33208|Metazoa	C	NAD(P) transhydrogenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB,PNTB_4TM
PYH1_k127_154669_3	1159870.KB907784_gene550	2.532e-51	190.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,3T1Y4@506|Alcaligenaceae	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
PYH1_k127_154669_0	522306.CAP2UW1_4180	4.944e-255	791.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,1KQK5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
PYH1_k127_154669_2	76114.ebA4052	1.679e-69	243.0	COG1556@1|root,COG1556@2|Bacteria,1R4TE@1224|Proteobacteria,2VJCF@28216|Betaproteobacteria,2KWJC@206389|Rhodocyclales	206389|Rhodocyclales	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
PYH1_k127_154669_1	926569.ANT_01840	1.245e-108	360.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
PYH1_k127_154669_5	511.JT27_09600	9.4e-14	74.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2VHEX@28216|Betaproteobacteria,3T33W@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_155943_0	1121035.AUCH01000003_gene1378	1.138e-113	388.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KUBP@206389|Rhodocyclales	206389|Rhodocyclales	KNT	COG0643 Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
PYH1_k127_1561244_1	1298867.AUES01000051_gene4507	7.225e-101	339.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2U22Z@28211|Alphaproteobacteria,3K3DU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23
PYH1_k127_1561244_0	909663.KI867150_gene334	1.314e-196	640.0	COG1994@1|root,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,42Q1P@68525|delta/epsilon subdivisions,2WM2R@28221|Deltaproteobacteria,2MRSH@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Peptidase M50	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,HlyD_3
PYH1_k127_1561244_2	136993.KB900627_gene71	7.879e-51	207.0	COG0653@1|root,COG0653@2|Bacteria,1MX0P@1224|Proteobacteria,2U086@28211|Alphaproteobacteria,371CY@31993|Methylocystaceae	28211|Alphaproteobacteria	U	SecA preprotein cross-linking domain	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind
PYH1_k127_1565084_4	269482.Bcep1808_5963	4.089e-67	242.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,1K0YC@119060|Burkholderiaceae	28216|Betaproteobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
PYH1_k127_1565084_9	1500897.JQNA01000001_gene6437	3.667e-30	132.0	COG2834@1|root,COG2834@2|Bacteria,1N09B@1224|Proteobacteria,2VVGD@28216|Betaproteobacteria,1JZVN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	-	-	-	-	-	-	-	-	-	LolA
PYH1_k127_1565084_6	640511.BC1002_2272	5.788e-51	188.0	COG0824@1|root,COG0824@2|Bacteria,1RH6W@1224|Proteobacteria,2VRI1@28216|Betaproteobacteria,1K6YC@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
PYH1_k127_1565084_1	1101195.Meth11DRAFT_2428	1.976e-101	340.0	COG1216@1|root,COG4261@1|root,COG1216@2|Bacteria,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2WH20@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Lip_A_acyltrans
PYH1_k127_1565084_3	1234364.AMSF01000036_gene275	4.776e-85	312.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,1T2BN@1236|Gammaproteobacteria,1XDEW@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PYH1_k127_1565084_13	1488328.JMCL01000052_gene3164	3.643e-19	103.0	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,1RRD5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
PYH1_k127_1565084_2	1562701.BBOF01000019_gene408	3.524e-90	314.0	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,2VIYA@28216|Betaproteobacteria,1JZSG@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	amp-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
PYH1_k127_1565084_8	1101195.Meth11DRAFT_2430	5.382e-43	164.0	COG4648@1|root,COG4648@2|Bacteria,1N0PK@1224|Proteobacteria,2VUK9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1565084_10	339670.Bamb_3600	1.33e-26	113.0	COG0236@1|root,COG0236@2|Bacteria,1N7Q1@1224|Proteobacteria,2VVRR@28216|Betaproteobacteria,1K9MR@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpM	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
PYH1_k127_1565084_12	290398.Csal_2749	8.018e-25	111.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,1SCW1@1236|Gammaproteobacteria,1XQ63@135619|Oceanospirillales	135619|Oceanospirillales	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
PYH1_k127_1565084_5	1101195.Meth11DRAFT_2433	1.519e-59	220.0	COG0204@1|root,COG0204@2|Bacteria,1RDN7@1224|Proteobacteria,2VNX6@28216|Betaproteobacteria,2KNY1@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
PYH1_k127_1565084_7	1458357.BG58_40815	1.111e-46	180.0	COG0304@1|root,COG0304@2|Bacteria,1P982@1224|Proteobacteria,2VT4H@28216|Betaproteobacteria,1K45X@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
PYH1_k127_1565084_14	391735.Veis_1317	3.665e-07	60.0	COG2091@1|root,COG2091@2|Bacteria,1NH1U@1224|Proteobacteria,2VXUG@28216|Betaproteobacteria,4AI27@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
PYH1_k127_1565084_0	316055.RPE_1790	2.724e-172	564.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2V4E1@28211|Alphaproteobacteria,3JWEG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
PYH1_k127_1565084_11	73044.JNXP01000005_gene383	5.289e-26	111.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria	201174|Actinobacteria	K	TetR Family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
PYH1_k127_1570013_12	1502852.FG94_01085	5.287e-38	151.0	COG2271@1|root,COG2271@2|Bacteria,1QU9E@1224|Proteobacteria,2WGJT@28216|Betaproteobacteria,473TE@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Major Facilitator Superfamily	fsr1	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
PYH1_k127_1570013_8	762376.AXYL_05754	6.323e-80	282.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VNWD@28216|Betaproteobacteria,3T5QG@506|Alcaligenaceae	28216|Betaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
PYH1_k127_1570013_5	883126.HMPREF9710_03579	1.258e-115	391.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2VHCA@28216|Betaproteobacteria,472PZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
PYH1_k127_1570013_7	290397.Adeh_2270	2.228e-95	322.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,4376S@68525|delta/epsilon subdivisions,2X26Y@28221|Deltaproteobacteria,2YWYG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
PYH1_k127_1570013_6	373994.Riv7116_6065	1.118e-96	324.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1HM7U@1161|Nostocales	1117|Cyanobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
PYH1_k127_1570013_2	269482.Bcep1808_6560	1.691e-202	675.0	COG4772@1|root,COG4772@2|Bacteria,1MXJU@1224|Proteobacteria,2VN9X@28216|Betaproteobacteria,1K2NQ@119060|Burkholderiaceae	28216|Betaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
PYH1_k127_1570013_4	62928.azo2935	1.157e-116	394.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2VM1W@28216|Betaproteobacteria,2KXH9@206389|Rhodocyclales	206389|Rhodocyclales	S	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
PYH1_k127_1570013_11	1504672.669786379	3.13e-41	171.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VS28@28216|Betaproteobacteria,4ADR4@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome B561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
PYH1_k127_1570013_10	365044.Pnap_3006	3.349e-54	198.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2VVSX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Ankyrin	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
PYH1_k127_1570013_0	365044.Pnap_3007	4.404e-303	937.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VMVP@28216|Betaproteobacteria,4AJ78@80864|Comamonadaceae	28216|Betaproteobacteria	G	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
PYH1_k127_1570013_9	1366050.N234_08055	3.66e-69	245.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2W0BP@28216|Betaproteobacteria,1K42R@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
PYH1_k127_1570013_1	1288494.EBAPG3_19390	9.356e-216	691.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,372G4@32003|Nitrosomonadales	28216|Betaproteobacteria	P	TonB-dependent Receptor Plug Domain	yncD	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
PYH1_k127_1570013_3	1100720.ALKN01000033_gene658	4.615e-185	586.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria,4ACEX@80864|Comamonadaceae	28216|Betaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,SGL
PYH1_k127_1570013_13	1100720.ALKN01000033_gene659	1.773e-06	55.0	COG2863@1|root,COG2863@2|Bacteria,1PFFQ@1224|Proteobacteria,2VXBF@28216|Betaproteobacteria,4AFPX@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH1_k127_1595307_2	1163617.SCD_n01807	4.086e-52	191.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
PYH1_k127_1595307_1	76114.ebA1258	2.72e-110	369.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,2KVKZ@206389|Rhodocyclales	206389|Rhodocyclales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
PYH1_k127_1595307_0	748247.AZKH_0810	3.724e-130	440.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,2KVNI@206389|Rhodocyclales	206389|Rhodocyclales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
PYH1_k127_1596678_2	76114.ebA6526	1.147e-81	275.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,2KUJF@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
PYH1_k127_1596678_1	1000565.METUNv1_00822	6.388e-175	561.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,2KUQ9@206389|Rhodocyclales	206389|Rhodocyclales	FP	Exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
PYH1_k127_1596678_0	93220.LV28_04405	5.04e-322	994.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,1JZSF@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
PYH1_k127_1596678_3	580332.Slit_1736	1.744e-77	264.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,44VQU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
PYH1_k127_1596678_5	1229205.BUPH_02987	3.081e-18	96.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,1K9H0@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
PYH1_k127_1596678_4	85643.Tmz1t_3022	6.421e-53	188.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,2KWC3@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
PYH1_k127_1596678_6	375286.mma_1491	2.613e-15	80.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,472F5@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
PYH1_k127_1607581_0	1121035.AUCH01000003_gene1213	1.674e-202	640.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,2KUB1@206389|Rhodocyclales	206389|Rhodocyclales	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
PYH1_k127_1607581_6	7460.GB49406-PA	1.409e-08	63.0	KOG3648@1|root,KOG3648@2759|Eukaryota,38DNM@33154|Opisthokonta,3BAF2@33208|Metazoa,3CRII@33213|Bilateria,41WNZ@6656|Arthropoda,3SHII@50557|Insecta,46G6Z@7399|Hymenoptera	33208|Metazoa	U	Cysteine rich repeat	GLG1	GO:0000137,GO:0000138,GO:0000139,GO:0001501,GO:0002376,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005797,GO:0005886,GO:0006810,GO:0006886,GO:0006928,GO:0007275,GO:0008104,GO:0008150,GO:0009653,GO:0009887,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010955,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016477,GO:0017015,GO:0017134,GO:0019222,GO:0019838,GO:0023051,GO:0023057,GO:0030162,GO:0030512,GO:0031012,GO:0031090,GO:0031224,GO:0031323,GO:0031324,GO:0031984,GO:0031985,GO:0032268,GO:0032269,GO:0032330,GO:0032501,GO:0032502,GO:0033036,GO:0034613,GO:0040011,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045861,GO:0046907,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050900,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051641,GO:0051649,GO:0051674,GO:0060255,GO:0060348,GO:0060349,GO:0061035,GO:0065007,GO:0070613,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0080090,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0098588,GO:0098791,GO:1903317,GO:1903318,GO:1903844,GO:1903845,GO:2000026	-	ko:K06816	ko04514,map04514	-	-	-	ko00000,ko00001,ko04516	-	-	-	Cys_rich_FGFR
PYH1_k127_1607581_4	525897.Dbac_1087	4.644e-25	111.0	2E8QN@1|root,3331M@2|Bacteria,1ND4I@1224|Proteobacteria,430TR@68525|delta/epsilon subdivisions,2WVZ7@28221|Deltaproteobacteria,2MF52@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1607581_3	62928.azo0320	9.923e-64	223.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,2KW7R@206389|Rhodocyclales	206389|Rhodocyclales	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
PYH1_k127_1607581_1	426117.M446_3953	5.721e-113	372.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,1JR56@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	TIGRFAM cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
PYH1_k127_1607581_2	1198452.Jab_1c21070	9.456e-110	361.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,47395@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
PYH1_k127_1611903_3	1384056.N787_07615	2.605e-17	86.0	COG3788@1|root,COG3788@2|Bacteria,1RDHP@1224|Proteobacteria,1S3PN@1236|Gammaproteobacteria,1X84I@135614|Xanthomonadales	135614|Xanthomonadales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
PYH1_k127_1611903_1	882378.RBRH_01237	5.434e-158	501.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,1K2NF@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
PYH1_k127_1611903_0	765912.Thimo_0241	1.165e-186	589.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales	135613|Chromatiales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
PYH1_k127_1611903_2	1122222.AXWR01000029_gene2233	1.112e-128	419.0	COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
PYH1_k127_1633094_1	1095769.CAHF01000011_gene2197	1.467e-203	665.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,47391@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
PYH1_k127_1633094_2	1392838.AWNM01000027_gene4541	4.645e-168	564.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2VIP8@28216|Betaproteobacteria,3T2UP@506|Alcaligenaceae	28216|Betaproteobacteria	I	PHB de-polymerase C-terminus	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	PHB_depo_C
PYH1_k127_1633094_8	400682.PAC_15704163	4.137e-44	170.0	COG1495@1|root,2SDDI@2759|Eukaryota,3AE24@33154|Opisthokonta,3BWEU@33208|Metazoa	33208|Metazoa	O	Disulfide bond formation protein DsbB	-	-	-	-	-	-	-	-	-	-	-	-	DsbB
PYH1_k127_1633094_0	75379.Tint_1734	3.585e-211	670.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VHMA@28216|Betaproteobacteria,1KKG1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
PYH1_k127_1633094_5	1100720.ALKN01000007_gene3065	1.643e-126	410.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VNQX@28216|Betaproteobacteria,4AC0P@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_1633094_3	1100720.ALKN01000007_gene3064	6.616e-141	471.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VKYI@28216|Betaproteobacteria,4A9Y9@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_1633094_7	1205680.CAKO01000002_gene3096	5.304e-102	356.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,2JR23@204441|Rhodospirillales	204441|Rhodospirillales	E	branched-chain amino acid transport	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH1_k127_1633094_6	1157708.KB907464_gene475	1.144e-117	387.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNC@28216|Betaproteobacteria,4ABEP@80864|Comamonadaceae	28216|Betaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_1633094_4	1157708.KB907464_gene476	2.885e-130	436.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,4A9UR@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
PYH1_k127_1650536_1	568706.BN118_3670	2.025e-19	90.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,3T2US@506|Alcaligenaceae	28216|Betaproteobacteria	GM	NAD dependent epimerase dehydratase family protein	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
PYH1_k127_1650536_0	1304883.KI912532_gene898	6.449e-140	456.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,2KU8J@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
PYH1_k127_1653933_13	1144319.PMI16_03301	5.088e-76	268.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,47245@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	negative regulator of sigma E activity	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
PYH1_k127_1653933_2	522306.CAP2UW1_1545	3.691e-188	602.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,1KQED@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
PYH1_k127_1653933_0	323848.Nmul_A1751	3.519e-312	964.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,372EW@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
PYH1_k127_1653933_7	1454004.AW11_03069	1.364e-109	386.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,1KQ9J@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
PYH1_k127_1653933_22	760117.JN27_04555	1.056e-14	86.0	COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,2VWEY@28216|Betaproteobacteria,474I1@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
PYH1_k127_1653933_16	987059.RBXJA2T_06050	3.794e-65	229.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,1KIXX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
PYH1_k127_1653933_11	640081.Dsui_2461	8.483e-94	326.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,2KVT3@206389|Rhodocyclales	206389|Rhodocyclales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
PYH1_k127_1653933_15	580332.Slit_1284	9.517e-66	250.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,44V76@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
PYH1_k127_1653933_5	1000565.METUNv1_00636	3.176e-118	400.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,2KV09@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
PYH1_k127_1653933_20	1288494.EBAPG3_14410	4.066e-26	121.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,373EI@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
PYH1_k127_1653933_8	292415.Tbd_0727	4.644e-106	360.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,1KRAB@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
PYH1_k127_1653933_12	323848.Nmul_A1268	1.199e-89	298.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VZ53@28216|Betaproteobacteria,374MG@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
PYH1_k127_1653933_1	1266925.JHVX01000001_gene2759	2.574e-222	704.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,371XJ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
PYH1_k127_1653933_14	1131553.JIBI01000001_gene1521	4.523e-75	265.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,372TT@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
PYH1_k127_1653933_17	420324.KI912014_gene9397	7.561e-55	197.0	COG1670@1|root,COG1670@2|Bacteria,1RF8W@1224|Proteobacteria,2U707@28211|Alphaproteobacteria,1JVHX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
PYH1_k127_1653933_6	420324.KI912077_gene8198	3.716e-115	376.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,1JS1W@119045|Methylobacteriaceae	28211|Alphaproteobacteria	IQ	TIGRFAM 3-hydroxybutyrate dehydrogenase	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
PYH1_k127_1653933_10	864069.MicloDRAFT_00018950	2.977e-94	329.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,1JUG5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	-	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH1_k127_1653933_9	1040989.AWZU01000001_gene5634	4.506e-101	342.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria,3JV6J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.5,2.8.3.8,2.8.3.9	ko:K01029,ko:K01035	ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH1_k127_1653933_4	1205680.CAKO01000007_gene4483	7.02e-127	411.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,2JPYY@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH1_k127_1653933_21	1198452.Jab_2c08590	9.214e-18	92.0	COG2172@1|root,COG2172@2|Bacteria,1PVRF@1224|Proteobacteria,2VYZ5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
PYH1_k127_1653933_19	1122604.JONR01000009_gene2312	2.213e-39	151.0	COG4254@1|root,COG4254@2|Bacteria,1N739@1224|Proteobacteria,1SE8D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
PYH1_k127_1653933_18	159087.Daro_1992	8.129e-42	160.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,2VU4E@28216|Betaproteobacteria,2KZ0C@206389|Rhodocyclales	206389|Rhodocyclales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
PYH1_k127_1653933_3	1232683.ADIMK_3832	3.986e-151	498.0	COG2208@1|root,COG4252@1|root,COG2208@2|Bacteria,COG4252@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,46BPT@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	Sigma factor PP2C-like phosphatases	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,HATPase_c_2,SpoIIE,dCache_1
PYH1_k127_1656071_8	574375.BAGA_09795	4.795e-24	116.0	2EV1B@1|root,33NGF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1656071_0	596153.Alide_4206	1.616e-262	842.0	COG0365@1|root,COG0365@2|Bacteria,1MXDK@1224|Proteobacteria,2VIAE@28216|Betaproteobacteria,4ABQD@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
PYH1_k127_1656071_3	1205680.CAKO01000010_gene3927	2.972e-140	456.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria,2JR9Q@204441|Rhodospirillales	204441|Rhodospirillales	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
PYH1_k127_1656071_4	1205680.CAKO01000010_gene3929	3.313e-112	374.0	COG3618@1|root,COG3618@2|Bacteria,1QWWJ@1224|Proteobacteria,2TV8V@28211|Alphaproteobacteria,2JVWZ@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1656071_9	1246459.KB898368_gene2569	4.405e-15	83.0	COG0664@1|root,COG0664@2|Bacteria,1RI6M@1224|Proteobacteria,2U9WH@28211|Alphaproteobacteria,4B9V7@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
PYH1_k127_1656071_1	795666.MW7_2938	3.739e-163	521.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,1K3VB@119060|Burkholderiaceae	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
PYH1_k127_1656071_7	1266925.JHVX01000003_gene535	5.18e-66	232.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,3721G@32003|Nitrosomonadales	28216|Betaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
PYH1_k127_1656071_6	261292.Nit79A3_3455	5.864e-72	250.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,37239@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
PYH1_k127_1656071_2	1163617.SCD_n02621	7.725e-161	511.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
PYH1_k127_1656071_12	1200557.JHWV01000032_gene2207	0.0009522	42.0	28RFR@1|root,2ZDUU@2|Bacteria,1W3TE@1239|Firmicutes,4H8JU@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1656071_5	292415.Tbd_0386	8.65e-97	326.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,1KRYI@119069|Hydrogenophilales	119069|Hydrogenophilales	I	GHMP kinases N terminal domain	-	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
PYH1_k127_1656071_11	1123392.AQWL01000002_gene2119	1.551e-05	48.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,2VUIR@28216|Betaproteobacteria,1KS6V@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Outer membrane lipoprotein LolB	-	-	-	-	-	-	-	-	-	-	-	-	LolB
PYH1_k127_1656885_1	1286106.MPL1_07443	2.343e-66	241.0	COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,1T0AA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer Membrane Lipoprotein	blc4	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
PYH1_k127_1656885_2	595537.Varpa_4422	5.131e-48	188.0	COG4338@1|root,COG4338@2|Bacteria,1N3G5@1224|Proteobacteria,2VUMZ@28216|Betaproteobacteria,4AF09@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1656885_0	765912.Thimo_2418	1.182e-93	312.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria,1WXW3@135613|Chromatiales	135613|Chromatiales	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
PYH1_k127_1681306_5	1123368.AUIS01000005_gene447	2.639e-84	297.0	COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,1RP34@1236|Gammaproteobacteria,2NBSM@225057|Acidithiobacillales	225057|Acidithiobacillales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
PYH1_k127_1681306_7	75379.Tint_1386	5.508e-52	190.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,1KM46@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
PYH1_k127_1681306_1	323848.Nmul_A1964	2.83e-185	586.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,372I8@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
PYH1_k127_1681306_4	1123393.KB891316_gene1414	1.194e-101	352.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,1KRBR@119069|Hydrogenophilales	119069|Hydrogenophilales	F	dUTPase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
PYH1_k127_1681306_2	1000565.METUNv1_02967	4.258e-175	555.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,2KV2W@206389|Rhodocyclales	206389|Rhodocyclales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
PYH1_k127_1681306_0	94624.Bpet4096	3.47e-291	908.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,3T1BH@506|Alcaligenaceae	28216|Betaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
PYH1_k127_1681306_6	580332.Slit_1269	2.722e-76	268.0	COG2114@1|root,COG2114@2|Bacteria,1RD0X@1224|Proteobacteria,2VS0D@28216|Betaproteobacteria,44VWF@713636|Nitrosomonadales	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,PEGA
PYH1_k127_1681306_8	1163617.SCD_n01783	6.646e-29	120.0	COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1681306_3	395494.Galf_1181	4.4e-102	342.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
PYH1_k127_170658_2	748247.AZKH_0728	1.354e-15	77.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2VH9V@28216|Betaproteobacteria,2KUF6@206389|Rhodocyclales	206389|Rhodocyclales	T	phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
PYH1_k127_170658_0	1158292.JPOE01000005_gene1191	1.336e-195	620.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,1KIX5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
PYH1_k127_170658_3	1000565.METUNv1_02101	8.216e-13	73.0	2AF5U@1|root,3154P@2|Bacteria,1PV4V@1224|Proteobacteria,2WB3A@28216|Betaproteobacteria,2KXID@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_170658_1	228410.NE1512	1.953e-61	221.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,372D2@32003|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	ubiF	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,SE
PYH1_k127_1744203_6	1123392.AQWL01000009_gene1109	2.776e-106	350.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,1KRGJ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
PYH1_k127_1744203_0	228410.NE1161	2.263e-289	913.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,372IT@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
PYH1_k127_1744203_5	1123354.AUDR01000018_gene1181	5.923e-124	403.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,1KRJ0@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Type I GTP cyclohydrolase folE2	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
PYH1_k127_1744203_8	296591.Bpro_4278	2.045e-73	258.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae	28216|Betaproteobacteria	O	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
PYH1_k127_1744203_3	1121861.KB899935_gene468	2.763e-156	498.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TSRF@28211|Alphaproteobacteria,2JQ3B@204441|Rhodospirillales	204441|Rhodospirillales	ET	general L-amino acid-binding periplasmic protein AapJ	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
PYH1_k127_1744203_4	1121106.JQKB01000047_gene3984	3.806e-133	447.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2TR9C@28211|Alphaproteobacteria,2JPI5@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0765 ABC-type amino acid transport system, permease component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
PYH1_k127_1744203_9	1095769.CAHF01000011_gene2698	1.184e-57	207.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria,4741T@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
PYH1_k127_1744203_7	1163617.SCD_n02190	6.7e-96	324.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria	28216|Betaproteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
PYH1_k127_1744203_1	1158292.JPOE01000002_gene3012	2.399e-209	672.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,1KJ2B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
PYH1_k127_1744203_2	1165096.ARWF01000001_gene544	1.823e-160	511.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,2KKJ5@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
PYH1_k127_1744203_10	640081.Dsui_3250	3.091e-25	107.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KUN2@206389|Rhodocyclales	206389|Rhodocyclales	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PYH1_k127_1756661_5	1380394.JADL01000002_gene1186	2.035e-27	115.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U7TT@28211|Alphaproteobacteria,2JWI6@204441|Rhodospirillales	204441|Rhodospirillales	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
PYH1_k127_1756661_4	1123073.KB899241_gene2933	1.342e-33	143.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1X7J5@135614|Xanthomonadales	135614|Xanthomonadales	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
PYH1_k127_1756661_2	1278073.MYSTI_07504	8.029e-65	231.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,435IS@68525|delta/epsilon subdivisions,2WZWF@28221|Deltaproteobacteria,2Z0UC@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
PYH1_k127_1756661_3	983917.RGE_09280	3.018e-51	186.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,1KKXD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
PYH1_k127_1756661_0	1288494.EBAPG3_7560	4.498e-201	643.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,372ME@32003|Nitrosomonadales	28216|Betaproteobacteria	I	AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
PYH1_k127_1756661_1	748247.AZKH_4266	4.081e-104	346.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,2KU6T@206389|Rhodocyclales	206389|Rhodocyclales	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
PYH1_k127_1758930_2	1159870.KB907784_gene658	1.12e-19	89.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,3T1TK@506|Alcaligenaceae	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
PYH1_k127_1758930_0	582744.Msip34_0459	2.412e-158	508.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,2KM9S@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
PYH1_k127_1758930_1	748247.AZKH_3726	3.961e-69	239.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,2KVGS@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
PYH1_k127_1766656_6	887898.HMPREF0551_0863	9.335e-31	122.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,1K2BU@119060|Burkholderiaceae	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
PYH1_k127_1766656_1	314278.NB231_02618	5.685e-141	459.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1WX22@135613|Chromatiales	135613|Chromatiales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PYH1_k127_1766656_0	1101195.Meth11DRAFT_2419	4.332e-175	565.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VIWC@28216|Betaproteobacteria,2KKN1@206350|Nitrosomonadales	1224|Proteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PYH1_k127_1766656_3	1101195.Meth11DRAFT_2420	2.075e-99	332.0	COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,2VK19@28216|Betaproteobacteria,2KNS4@206350|Nitrosomonadales	206350|Nitrosomonadales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH1_k127_1766656_5	267608.RSp0360	9.993e-37	149.0	COG4706@1|root,COG4706@2|Bacteria,1N00A@1224|Proteobacteria,2VUZ2@28216|Betaproteobacteria,1K568@119060|Burkholderiaceae	28216|Betaproteobacteria	I	PFAM Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA FabZ	-	-	-	-	-	-	-	-	-	-	-	-	FabA
PYH1_k127_1766656_2	1101195.Meth11DRAFT_2422	1.888e-131	442.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,2VJR3@28216|Betaproteobacteria,2KNP2@206350|Nitrosomonadales	206350|Nitrosomonadales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PYH1_k127_1766656_8	1101195.Meth11DRAFT_2423	2.154e-06	60.0	2EUGK@1|root,33MYU@2|Bacteria,1NP8U@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3261)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3261
PYH1_k127_1766656_4	1071679.BG57_05655	8.59e-97	331.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,1K0YC@119060|Burkholderiaceae	28216|Betaproteobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
PYH1_k127_1769027_7	1000565.METUNv1_02453	4.421e-36	139.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
PYH1_k127_1769027_1	1000565.METUNv1_02454	4.237e-270	850.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,2KVW3@206389|Rhodocyclales	206389|Rhodocyclales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
PYH1_k127_1769027_4	580332.Slit_0534	2.438e-110	363.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,44W4T@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SMART beta-lactamase domain protein	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
PYH1_k127_1769027_0	580332.Slit_0536	0.0	1144.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44VNC@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GAF,T2SSE,T2SSE_N
PYH1_k127_1769027_2	580332.Slit_0537	1.824e-238	749.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,44W5N@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
PYH1_k127_1769027_3	1123393.KB891333_gene2602	7.042e-133	449.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria	28216|Betaproteobacteria	O	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,SEC-C,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
PYH1_k127_1769027_8	395495.Lcho_0488	2.117e-08	61.0	2911D@1|root,2ZNNZ@2|Bacteria,1P8DV@1224|Proteobacteria,2W5MI@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1769027_5	1294143.H681_04940	7.353e-45	167.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650,ko:K02655	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
PYH1_k127_1769027_6	1294143.H681_04940	1.089e-44	167.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650,ko:K02655	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
PYH1_k127_1775003_19	1380394.JADL01000003_gene5125	8.574e-21	104.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2TTDW@28211|Alphaproteobacteria,2JRVY@204441|Rhodospirillales	204441|Rhodospirillales	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
PYH1_k127_1775003_15	1380394.JADL01000003_gene5124	2.65e-38	145.0	COG5501@1|root,COG5501@2|Bacteria,1N03V@1224|Proteobacteria,2TWQY@28211|Alphaproteobacteria,2JUCR@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulphur oxidation protein SoxZ	-	-	-	-	-	-	-	-	-	-	-	-	SoxZ
PYH1_k127_1775003_14	113395.AXAI01000014_gene177	2.889e-40	156.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2U72E@28211|Alphaproteobacteria,3JUV9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Sulfur oxidation protein SoxY	MA20_17510	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
PYH1_k127_1775003_13	1121106.JQKB01000015_gene5849	2.743e-42	170.0	COG2010@1|root,COG2010@2|Bacteria,1RIV2@1224|Proteobacteria,2U9C5@28211|Alphaproteobacteria,2JT7V@204441|Rhodospirillales	204441|Rhodospirillales	C	cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
PYH1_k127_1775003_0	1304878.AUGD01000007_gene5581	0.0	1097.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,3JSW3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	MA20_17495	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
PYH1_k127_1775003_10	189753.AXAS01000044_gene6196	8.203e-66	232.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,3JQR4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	MA20_17490	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PYH1_k127_1775003_12	864051.BurJ1DRAFT_1754	6.125e-50	183.0	COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,2VSYU@28216|Betaproteobacteria,1KM8J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Carboxymuconolactone decarboxylase family	pcaC	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,CMD
PYH1_k127_1775003_2	1123393.KB891326_gene83	2.471e-228	720.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1KSJ5@119069|Hydrogenophilales	119069|Hydrogenophilales	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8
PYH1_k127_1775003_3	338969.Rfer_0826	1.734e-163	524.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VSBW@28216|Betaproteobacteria,4AGV6@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
PYH1_k127_1775003_4	1158292.JPOE01000005_gene216	2.604e-150	505.0	COG0277@1|root,COG0277@2|Bacteria,1N4UQ@1224|Proteobacteria,2W1U4@28216|Betaproteobacteria	28216|Betaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
PYH1_k127_1775003_20	580332.Slit_2152	1.323e-19	93.0	2E1DK@1|root,32WSU@2|Bacteria,1N3VJ@1224|Proteobacteria,2VV0D@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1775003_16	404589.Anae109_0819	6.449e-38	154.0	COG0529@1|root,COG0529@2|Bacteria,1QTVY@1224|Proteobacteria,434UM@68525|delta/epsilon subdivisions,2WZ5M@28221|Deltaproteobacteria,2Z1DN@29|Myxococcales	28221|Deltaproteobacteria	P	Adenylylsulfate kinase	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
PYH1_k127_1775003_8	330214.NIDE3770	1.207e-117	388.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
PYH1_k127_1775003_7	648996.Theam_1075	2.908e-127	419.0	COG1812@1|root,COG1812@2|Bacteria,2G3UM@200783|Aquificae	200783|Aquificae	E	PFAM S-adenosylmethionine synthetase (MAT)	-	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_Synthase
PYH1_k127_1775003_1	1163617.SCD_n00861	2.169e-312	980.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
PYH1_k127_1775003_18	1255043.TVNIR_1504	2.374e-26	113.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,1SAW8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	dksA traR	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
PYH1_k127_1775003_11	1288494.EBAPG3_20620	1.01e-61	218.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria,372T2@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
PYH1_k127_1775003_6	338969.Rfer_1232	7.19e-135	437.0	COG1234@1|root,COG1234@2|Bacteria,1PPRD@1224|Proteobacteria,2VNMY@28216|Betaproteobacteria,4AGEE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
PYH1_k127_1775003_9	261292.Nit79A3_2699	2.736e-98	331.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,2VHYS@28216|Betaproteobacteria,373YE@32003|Nitrosomonadales	28216|Betaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
PYH1_k127_1775003_5	502025.Hoch_1666	1.904e-141	466.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2YUFH@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_1775003_17	742159.HMPREF0004_4717	2.849e-31	130.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria	28216|Betaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH1_k127_1796642_10	1122194.AUHU01000004_gene1448	1.497e-05	57.0	COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
PYH1_k127_1796642_9	395495.Lcho_1337	3.226e-09	62.0	COG4654@1|root,COG4654@2|Bacteria,1MZJM@1224|Proteobacteria,2VV99@28216|Betaproteobacteria,1KMK6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
PYH1_k127_1796642_8	1101195.Meth11DRAFT_0428	6.263e-13	73.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KMZ0@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
PYH1_k127_1796642_3	159087.Daro_3859	3.012e-47	184.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,2KWMI@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome c5	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH1_k127_1796642_5	702113.PP1Y_AT23279	4.366e-20	103.0	2E92Z@1|root,333BY@2|Bacteria,1N8J4@1224|Proteobacteria,2UI81@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1796642_11	640511.BC1002_0860	0.0002803	54.0	COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,2VU50@28216|Betaproteobacteria,1K735@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome c class	cytC2	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
PYH1_k127_1796642_4	1265503.KB905171_gene505	6.548e-26	124.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q646@267889|Colwelliaceae	1236|Gammaproteobacteria	C	Cytochrome c	cc4	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
PYH1_k127_1796642_2	1485545.JQLW01000005_gene922	4.38e-51	199.0	293CN@1|root,2Z9VJ@2|Bacteria,1MXNG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1796642_6	1415780.JPOG01000001_gene3314	4.38e-20	103.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1X4PC@135614|Xanthomonadales	135614|Xanthomonadales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
PYH1_k127_1796642_7	546267.NEIPOLOT_00359	1.468e-14	86.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,2KQ5J@206351|Neisseriales	206351|Neisseriales	C	Psort location Periplasmic, score	cyc	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
PYH1_k127_1796642_0	404589.Anae109_3085	2.469e-96	333.0	COG5557@1|root,COG5557@2|Bacteria,1R7R0@1224|Proteobacteria,42P0Z@68525|delta/epsilon subdivisions,2X7KR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
PYH1_k127_1796642_1	443144.GM21_1067	9.33e-70	244.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,43T2N@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
PYH1_k127_1803297_2	189753.AXAS01000030_gene7110	2.656e-126	412.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria,3JW29@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	MA20_06335	-	4.2.1.156,4.2.1.42,5.1.2.2	ko:K01781,ko:K20023	ko00053,ko00627,ko01120,map00053,map00627,map01120	-	R03791,R04161,R05608	RC00543,RC00998	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
PYH1_k127_1803297_0	75379.Tint_1587	8.885e-213	684.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIA6@28216|Betaproteobacteria,1KKA9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD2	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
PYH1_k127_1803297_4	1429916.X566_21155	1.976e-27	130.0	COG2847@1|root,COG4549@1|root,COG2847@2|Bacteria,COG4549@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria,3JX1P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	DUF1775,PCuAC
PYH1_k127_1803297_1	1366050.N234_13210	1.875e-158	505.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,1K25Z@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
PYH1_k127_1803297_3	391038.Bphy_0916	2.227e-86	289.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,2VKF1@28216|Betaproteobacteria,1K3P4@119060|Burkholderiaceae	28216|Betaproteobacteria	P	phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
PYH1_k127_1803297_5	749927.AMED_3835	0.000408	43.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4DYUC@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
PYH1_k127_1827433_10	76114.ebA4383	1.36e-06	50.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria,2KUG3@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
PYH1_k127_1827433_8	1288494.EBAPG3_5100	3.481e-33	141.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,3738A@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
PYH1_k127_1827433_0	1123354.AUDR01000016_gene1270	0.0	1221.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,1KS1K@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Leucyl-tRNA synthetase, Domain 2	-	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
PYH1_k127_1827433_9	795666.MW7_1791	1.411e-20	96.0	COG3181@1|root,COG3181@2|Bacteria,1NTB7@1224|Proteobacteria,2W167@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_1827433_1	1123392.AQWL01000005_gene3196	3.602e-284	896.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,1KSQ2@119069|Hydrogenophilales	119069|Hydrogenophilales	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PYH1_k127_1827433_3	1298867.AUES01000015_gene3825	1.727e-187	604.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3JV88@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_1827433_7	1304883.KI912532_gene915	2.746e-36	142.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria,2KWWC@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1827433_2	1163617.SCD_n00393	6.659e-231	723.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
PYH1_k127_1827433_4	713586.KB900536_gene470	1.451e-83	282.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,1S02F@1236|Gammaproteobacteria,1WXYH@135613|Chromatiales	135613|Chromatiales	S	PFAM O-methyltransferase, family 3	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
PYH1_k127_1827433_5	1000565.METUNv1_02334	1.11e-49	183.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2VJZE@28216|Betaproteobacteria,2KWQ6@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	5-FTHF_cyc-lig
PYH1_k127_1827433_6	1454004.AW11_00159	1.651e-41	160.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,1KQAK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Soluble lytic murein transglycosylase L domain	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
PYH1_k127_1843736_14	62928.azo1339	1.381e-106	357.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,2KV1V@206389|Rhodocyclales	206389|Rhodocyclales	P	cation transport ATPase	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
PYH1_k127_1843736_22	1123393.KB891316_gene1605	7.202e-41	155.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,1KT32@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
PYH1_k127_1843736_1	748247.AZKH_1051	7.377e-221	692.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VJ6T@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3501
PYH1_k127_1843736_26	509190.Cseg_3269	4.083e-20	102.0	COG2519@1|root,COG2519@2|Bacteria,1RM3Z@1224|Proteobacteria,2UDX0@28211|Alphaproteobacteria,2KJK1@204458|Caulobacterales	204458|Caulobacterales	J	Vibrio cholerae RfbT protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
PYH1_k127_1843736_19	159087.Daro_2348	1.32e-51	194.0	COG1409@1|root,COG1409@2|Bacteria,1MV0H@1224|Proteobacteria,2VPKR@28216|Betaproteobacteria,2KX4Z@206389|Rhodocyclales	206389|Rhodocyclales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1843736_5	1288494.EBAPG3_24930	1.446e-191	611.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,372MN@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
PYH1_k127_1843736_3	1288494.EBAPG3_24940	1.177e-200	653.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,372HP@32003|Nitrosomonadales	28216|Betaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
PYH1_k127_1843736_2	1007105.PT7_0474	1.566e-220	687.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VI7S@28216|Betaproteobacteria,3T1HH@506|Alcaligenaceae	28216|Betaproteobacteria	E	Aminotransferase	alaC	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH1_k127_1843736_25	1454004.AW11_01682	7.097e-34	149.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,1KQ5E@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
PYH1_k127_1843736_10	1454004.AW11_03265	4.088e-126	427.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,1KQDW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
PYH1_k127_1843736_20	1163617.SCD_n01750	1.024e-44	184.0	COG2076@1|root,COG2076@2|Bacteria,1NAUF@1224|Proteobacteria,2WE9Q@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
PYH1_k127_1843736_8	522306.CAP2UW1_3296	8.605e-159	514.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KQ9V@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
PYH1_k127_1843736_12	522306.CAP2UW1_3295	8.175e-121	401.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,1KQBS@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	arnC	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
PYH1_k127_1843736_15	1163617.SCD_n01753	1.173e-103	349.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,2VKAI@28216|Betaproteobacteria	28216|Betaproteobacteria	J	PFAM formyl transferase domain protein	pmrIa	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
PYH1_k127_1843736_7	1158292.JPOE01000002_gene2806	5.201e-172	545.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2VJV2@28216|Betaproteobacteria,1KKIW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	NAD(P)H-binding	pmrIb	-	-	-	-	-	-	-	-	-	-	-	Epimerase
PYH1_k127_1843736_11	1163617.SCD_n01755	1.664e-121	397.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,2VKEP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	polysaccharide deacetylase	arnD	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
PYH1_k127_1843736_13	1479237.JMLY01000001_gene3233	4.542e-109	365.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,1RP4M@1236|Gammaproteobacteria,46CWZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
PYH1_k127_1843736_28	264198.Reut_A1996	0.0003116	44.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria	28216|Betaproteobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
PYH1_k127_1843736_0	497321.C664_06648	1.576e-230	724.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,2KUNN@206389|Rhodocyclales	206389|Rhodocyclales	T	ATPase related to phosphate starvation-inducible protein PhoH	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
PYH1_k127_1843736_16	1268622.AVS7_01343	8.511e-75	261.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2WGJ7@28216|Betaproteobacteria,4AHEN@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
PYH1_k127_1843736_23	472759.Nhal_2660	1.504e-35	136.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,1SCN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
PYH1_k127_1843736_21	580332.Slit_2043	1.708e-42	166.0	COG4254@1|root,COG4254@2|Bacteria,1NBPR@1224|Proteobacteria,2VWWI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
PYH1_k127_1843736_4	1288494.EBAPG3_25740	2.132e-198	627.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,372T4@32003|Nitrosomonadales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
PYH1_k127_1843736_17	62928.azo0721	1.139e-59	212.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,2KWBY@206389|Rhodocyclales	206389|Rhodocyclales	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
PYH1_k127_1843736_24	1000565.METUNv1_00772	2.129e-35	137.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,2KWXF@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
PYH1_k127_1843736_27	640081.Dsui_1990	3.526e-15	84.0	COG2965@1|root,COG2965@2|Bacteria,1N98W@1224|Proteobacteria,2VVZ4@28216|Betaproteobacteria,2KX33@206389|Rhodocyclales	206389|Rhodocyclales	L	Binds single-stranded DNA at the primosome assembly site (PAS)	priB	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
PYH1_k127_1843736_18	640081.Dsui_1989	8.403e-59	209.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,2KWGN@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
PYH1_k127_1843736_9	573370.DMR_01260	3.154e-134	433.0	2D663@1|root,32TKM@2|Bacteria,1N455@1224|Proteobacteria,43DKS@68525|delta/epsilon subdivisions,2X8RY@28221|Deltaproteobacteria,2MFRP@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_1843736_6	573370.DMR_01270	5.924e-184	578.0	COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,42WCT@68525|delta/epsilon subdivisions,2WRX3@28221|Deltaproteobacteria,2MEBR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
PYH1_k127_2000203_1	316057.RPD_3715	3.416e-237	756.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TRRY@28211|Alphaproteobacteria,3JRVU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	MA20_04660	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH1_k127_2000203_6	555778.Hneap_0870	4.895e-102	340.0	COG3248@1|root,COG3248@2|Bacteria,1R7UE@1224|Proteobacteria,1S1P9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Nucleoside-binding outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2000203_11	194867.ALBQ01000011_gene384	0.0001815	45.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
PYH1_k127_2000203_4	395493.BegalDRAFT_2197	3.144e-156	508.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,45ZPQ@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
PYH1_k127_2000203_2	1000565.METUNv1_02872	5.189e-207	650.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,2KUDF@206389|Rhodocyclales	206389|Rhodocyclales	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C
PYH1_k127_2000203_8	1304883.KI912532_gene2952	6.104e-61	217.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,2KWH0@206389|Rhodocyclales	206389|Rhodocyclales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
PYH1_k127_2000203_0	580332.Slit_2580	3.926e-307	959.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,44VA1@713636|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
PYH1_k127_2000203_9	29581.BW37_01717	6.857e-49	183.0	COG3712@1|root,COG3712@2|Bacteria,1QUYQ@1224|Proteobacteria,2WGKW@28216|Betaproteobacteria	28216|Betaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
PYH1_k127_2000203_7	522306.CAP2UW1_2298	1.168e-75	260.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VKF3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator crp fnr family	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
PYH1_k127_2000203_5	29581.BW37_01719	9.369e-125	419.0	COG2831@1|root,COG2831@2|Bacteria,1PRBP@1224|Proteobacteria,2VHDS@28216|Betaproteobacteria,475Q6@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	POTRA,POTRA_2,ShlB
PYH1_k127_2000203_3	76114.ebA7042	3.872e-157	507.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,2KUD7@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PYH1_k127_2000203_10	1123368.AUIS01000017_gene2598	9.629e-09	63.0	COG2840@1|root,COG2840@2|Bacteria,1MVS6@1224|Proteobacteria,1RPXD@1236|Gammaproteobacteria,2NCWH@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
PYH1_k127_2014087_5	1461694.ATO9_18195	1.604e-07	54.0	COG1028@1|root,COG1028@2|Bacteria,1R3TE@1224|Proteobacteria,2U55K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_2014087_1	1205680.CAKO01000004_gene3605	8.479e-123	399.0	COG1028@1|root,COG1028@2|Bacteria,1R4GD@1224|Proteobacteria,2TVNF@28211|Alphaproteobacteria,2JWE1@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_2014087_0	381666.H16_A2854	2.324e-139	466.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,1K0U6@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
PYH1_k127_2014087_2	76114.ebA3566	4.3e-39	153.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2VQGE@28216|Betaproteobacteria,2KW8Z@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
PYH1_k127_2014087_3	522306.CAP2UW1_4317	1.428e-36	150.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria,1KQ2S@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
PYH1_k127_2014087_4	1163617.SCD_n00844	4.396e-32	136.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
PYH1_k127_2026917_0	76114.ebA4201	1.117e-84	284.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,2KU9A@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
PYH1_k127_2026917_2	1231391.AMZF01000022_gene1242	6.107e-10	72.0	COG2831@1|root,COG3203@1|root,COG2831@2|Bacteria,COG3203@2|Bacteria,1MWEC@1224|Proteobacteria,2VJXF@28216|Betaproteobacteria,3T55Y@506|Alcaligenaceae	28216|Betaproteobacteria	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
PYH1_k127_2026917_1	305700.B447_07327	4.129e-59	211.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,2KUDE@206389|Rhodocyclales	206389|Rhodocyclales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
PYH1_k127_2059804_6	1000565.METUNv1_02443	1.503e-09	59.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,2KV5H@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase S1C family	-	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
PYH1_k127_2059804_4	159087.Daro_0809	2.638e-75	259.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,2KVZE@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
PYH1_k127_2059804_1	1123393.KB891316_gene1115	6.33e-209	655.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1KRDP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
PYH1_k127_2059804_3	323848.Nmul_A1003	1.373e-77	289.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,37206@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
PYH1_k127_2059804_2	358220.C380_04515	1.922e-98	325.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,4AAHE@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
PYH1_k127_2059804_5	1304883.KI912532_gene1724	1.803e-42	160.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,2KX0Y@206389|Rhodocyclales	206389|Rhodocyclales	S	stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
PYH1_k127_2059804_0	159087.Daro_0465	2.182e-262	824.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
PYH1_k127_2121233_0	1217718.ALOU01000019_gene2703	1.5e-323	1014.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,1K087@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Atp-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
PYH1_k127_2123167_2	640081.Dsui_3143	4.741e-22	98.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,2KWMY@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
PYH1_k127_2123167_0	582744.Msip34_1716	1.562e-195	622.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,2KMH4@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
PYH1_k127_2123167_1	748247.AZKH_0807	1.206e-138	469.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,2KUKY@206389|Rhodocyclales	206389|Rhodocyclales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
PYH1_k127_2130339_0	640081.Dsui_2309	1.899e-149	478.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,2KUV8@206389|Rhodocyclales	206389|Rhodocyclales	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
PYH1_k127_2130339_1	1349767.GJA_2398	3.584e-113	376.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,472FU@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
PYH1_k127_215424_0	1266925.JHVX01000008_gene274	1.024e-176	571.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,372V1@32003|Nitrosomonadales	28216|Betaproteobacteria	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
PYH1_k127_215424_1	713587.THITH_15760	6.598e-45	168.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1WWYC@135613|Chromatiales	135613|Chromatiales	JM	PFAM Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
PYH1_k127_2194080_2	1121861.KB899950_gene2352	8.022e-95	339.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2TVMU@28211|Alphaproteobacteria,2JU2U@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH1_k127_2194080_0	1123393.KB891328_gene553	5.6e-219	703.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,1KRFC@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
PYH1_k127_2194080_1	1235457.C404_17975	8.891e-100	350.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,1K2WY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
PYH1_k127_2194080_3	1163617.SCD_n01950	1.355e-69	251.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
PYH1_k127_2204774_5	497321.C664_11325	2.384e-146	473.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,2KV3Q@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN1	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
PYH1_k127_2204774_20	640081.Dsui_0703	1.451e-29	134.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,2KWTT@206389|Rhodocyclales	206389|Rhodocyclales	J	sigma 54 modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
PYH1_k127_2204774_16	626418.bglu_1g31230	5.75e-62	217.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,1K48R@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
PYH1_k127_2204774_13	640081.Dsui_0701	2.932e-97	327.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,2KVU0@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
PYH1_k127_2204774_14	497321.C664_03872	2.738e-95	333.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,2KUWU@206389|Rhodocyclales	206389|Rhodocyclales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
PYH1_k127_2204774_17	640081.Dsui_0994	1.681e-57	220.0	COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,2VSA4@28216|Betaproteobacteria,2KWC8@206389|Rhodocyclales	206389|Rhodocyclales	S	peptidase S16	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
PYH1_k127_2204774_12	1163617.SCD_n00536	4.19e-110	365.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria	28216|Betaproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
PYH1_k127_2204774_6	1380394.JADL01000008_gene3545	1.42e-144	466.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR3F@28211|Alphaproteobacteria,2JQU0@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PYH1_k127_2204774_4	257310.BB4209	3.126e-152	490.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VM4Z@28216|Betaproteobacteria,3T8WW@506|Alcaligenaceae	28216|Betaproteobacteria	S	Metal-dependent amidase aminoacylase carboxypeptidase	yxeP_2	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH1_k127_2204774_2	864051.BurJ1DRAFT_2978	2.38e-235	738.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VHCV@28216|Betaproteobacteria,1KJIQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH1_k127_2204774_8	360910.BAV2802	2.176e-139	449.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VIN2@28216|Betaproteobacteria,3T1KQ@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PYH1_k127_2204774_3	1156919.QWC_22739	6.252e-154	499.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria,3T2XD@506|Alcaligenaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_2204774_7	1380394.JADL01000008_gene3543	4.172e-141	456.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,2JPE7@204441|Rhodospirillales	204441|Rhodospirillales	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_2204774_11	1000565.METUNv1_03446	4.216e-125	430.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,2KWW5@206389|Rhodocyclales	206389|Rhodocyclales	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
PYH1_k127_2204774_10	93220.LV28_18230	2.612e-129	419.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,2VJKN@28216|Betaproteobacteria,1K02S@119060|Burkholderiaceae	28216|Betaproteobacteria	S	5'-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
PYH1_k127_2204774_22	1033734.CAET01000079_gene3557	0.0001856	53.0	29S70@1|root,30DBH@2|Bacteria,1UB40@1239|Firmicutes,4IMGK@91061|Bacilli,1ZK45@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2204774_18	380394.Lferr_0210	3.655e-50	182.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1T9P7@1236|Gammaproteobacteria,2NDUI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
PYH1_k127_2204774_21	292415.Tbd_2127	2.463e-20	92.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VVVB@28216|Betaproteobacteria,1KTG0@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
PYH1_k127_2204774_19	1380394.JADL01000011_gene3820	1.06e-38	152.0	COG1764@1|root,COG1764@2|Bacteria,1RHVR@1224|Proteobacteria,2VG83@28211|Alphaproteobacteria,2JTM8@204441|Rhodospirillales	204441|Rhodospirillales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
PYH1_k127_2204774_9	1236959.BAMT01000007_gene2714	3.734e-135	437.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,2KKDX@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
PYH1_k127_2204774_15	1123354.AUDR01000011_gene1482	1.205e-83	295.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,1KRJ6@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Putative methyltransferase	-	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
PYH1_k127_2204774_0	420324.KI912061_gene6197	0.0	1077.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,1JR57@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,Guanylate_cyc,TPR_4
PYH1_k127_2204774_1	420324.KI912061_gene6197	1.878e-273	876.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,1JR57@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,Guanylate_cyc,TPR_4
PYH1_k127_2208417_3	1097668.BYI23_A001570	1.871e-19	89.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,1K488@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PYH1_k127_2208417_1	1100720.ALKN01000030_gene1143	1.561e-177	586.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,4AAXN@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	-	SSF
PYH1_k127_2208417_0	883126.HMPREF9710_00318	5.331e-197	633.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,473XB@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
PYH1_k127_2208417_2	1123367.C666_13795	1.465e-20	96.0	COG3165@1|root,COG3165@2|Bacteria,1N314@1224|Proteobacteria,2VU2B@28216|Betaproteobacteria,2KWVA@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
PYH1_k127_2211892_5	159087.Daro_1282	2.054e-16	81.0	COG5416@1|root,COG5416@2|Bacteria,1N4UI@1224|Proteobacteria,2VU63@28216|Betaproteobacteria,2KXEI@206389|Rhodocyclales	206389|Rhodocyclales	S	Lipopolysaccharide assembly protein A domain	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
PYH1_k127_2211892_4	1123367.C666_02715	1.401e-47	172.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,2KWNF@206389|Rhodocyclales	206389|Rhodocyclales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
PYH1_k127_2211892_0	323848.Nmul_A2069	3.934e-292	905.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,372RZ@32003|Nitrosomonadales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
PYH1_k127_2211892_3	1392838.AWNM01000004_gene1818	1.391e-70	246.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2VQ2F@28216|Betaproteobacteria,3T3FH@506|Alcaligenaceae	28216|Betaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
PYH1_k127_2211892_1	243365.CV_3048	1.837e-169	553.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,2KPZS@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
PYH1_k127_2211892_2	748247.AZKH_3557	3.041e-77	265.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,2KU90@206389|Rhodocyclales	206389|Rhodocyclales	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
PYH1_k127_2223975_0	290397.Adeh_2245	1.15e-205	647.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,2YTUB@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH1_k127_2223975_1	1380355.JNIJ01000004_gene2787	9.649e-79	271.0	COG2358@1|root,COG2358@2|Bacteria,1NRH6@1224|Proteobacteria,2TT34@28211|Alphaproteobacteria,3JTPF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
PYH1_k127_2244576_9	1449049.JONW01000008_gene520	1.836e-11	68.0	2E5SP@1|root,330H2@2|Bacteria,1Q9TH@1224|Proteobacteria,2UGZT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
PYH1_k127_2244576_6	1366050.N234_34995	3.88e-40	157.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,2VWAN@28216|Betaproteobacteria,1K4AW@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2244576_3	264198.Reut_B3664	8.671e-82	296.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_2244576_10	316057.RPD_3121	1.06e-05	59.0	2E041@1|root,32VSR@2|Bacteria,1N6B9@1224|Proteobacteria,2UFQ6@28211|Alphaproteobacteria,3K181@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
PYH1_k127_2244576_1	864051.BurJ1DRAFT_1850	2.102e-91	304.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria,1KKZQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
PYH1_k127_2244576_5	1122604.JONR01000010_gene3877	4.82e-50	191.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,1X72V@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
PYH1_k127_2244576_0	204773.HEAR1081	7.161e-93	310.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria,474I0@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
PYH1_k127_2244576_8	94624.Bpet3840	2.48e-29	128.0	COG3189@1|root,COG3189@2|Bacteria,1RHYB@1224|Proteobacteria,2VSIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
PYH1_k127_2244576_4	1095769.CAHF01000015_gene2793	1.506e-66	228.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2VRD4@28216|Betaproteobacteria,477DK@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	gloA3	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH1_k127_2244576_7	525897.Dbac_2128	3.071e-32	131.0	COG2149@1|root,COG2149@2|Bacteria,1N173@1224|Proteobacteria,42XPI@68525|delta/epsilon subdivisions,2WSVB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
PYH1_k127_2244576_2	344747.PM8797T_21498	1.457e-86	295.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HDOD,Pkinase,dCache_1
PYH1_k127_2253607_0	396588.Tgr7_0082	5.226e-154	526.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2QR@135613|Chromatiales	135613|Chromatiales	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
PYH1_k127_2253607_1	1123368.AUIS01000032_gene1387	1.93e-128	420.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,2NCPY@225057|Acidithiobacillales	225057|Acidithiobacillales	T	HD domain	-	-	-	ko:K13815	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HD,Response_reg
PYH1_k127_2253607_2	1163617.SCD_n02213	1.888e-77	265.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
PYH1_k127_2327554_0	1165096.ARWF01000001_gene946	2.44e-95	321.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria,2KKSH@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
PYH1_k127_2327554_1	292415.Tbd_1253	5.699e-79	269.0	COG2210@1|root,COG2210@2|Bacteria,1QCK1@1224|Proteobacteria,2WE8S@28216|Betaproteobacteria,1KSAI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
PYH1_k127_2327554_2	1000565.METUNv1_02465	5.737e-30	121.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,2KWXB@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
PYH1_k127_2327554_3	1009370.ALO_05605	5.094e-13	74.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1UYMY@1239|Firmicutes,4H244@909932|Negativicutes	909932|Negativicutes	S	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
PYH1_k127_2380502_11	926550.CLDAP_16330	1.079e-07	64.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
PYH1_k127_2380502_1	795666.MW7_0760	7.904e-148	479.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH1_k127_2380502_4	1157490.EL26_00040	1.559e-87	304.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,279A2@186823|Alicyclobacillaceae	91061|Bacilli	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH1_k127_2380502_2	795666.MW7_0758	2.53e-122	410.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,1K50V@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
PYH1_k127_2380502_6	365046.Rta_37260	1.918e-69	257.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,2VQUC@28216|Betaproteobacteria,4AF9N@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
PYH1_k127_2380502_0	290397.Adeh_2279	4.493e-255	797.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
PYH1_k127_2380502_7	1217718.ALOU01000009_gene1094	1.148e-50	186.0	COG2010@1|root,COG2010@2|Bacteria,1P1GY@1224|Proteobacteria,2VP4W@28216|Betaproteobacteria,1K68I@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
PYH1_k127_2380502_5	290397.Adeh_2281	8.157e-84	288.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,42MIC@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	soxA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564	1.8.2.2	ko:K17222,ko:K19713	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	-
PYH1_k127_2380502_10	1304883.KI912532_gene3099	2.802e-34	134.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,2KX4B@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
PYH1_k127_2380502_9	1123392.AQWL01000004_gene2625	2.303e-48	177.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
PYH1_k127_2380502_8	859657.RPSI07_2794	1.084e-49	195.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,1K4PP@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
PYH1_k127_2380502_3	1454004.AW11_00793	7.463e-92	321.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,1KQ94@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase family M48	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
PYH1_k127_2391455_3	1123393.KB891329_gene1034	1.245e-50	186.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,2VKK9@28216|Betaproteobacteria,1KSYH@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
PYH1_k127_2391455_2	614083.AWQR01000040_gene755	5.702e-102	342.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria,2VK63@28216|Betaproteobacteria,4AA5X@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
PYH1_k127_2391455_5	338969.Rfer_1222	5.851e-41	169.0	29DRS@1|root,300PM@2|Bacteria,1RF8B@1224|Proteobacteria,2VR3X@28216|Betaproteobacteria,4AE2G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2391455_0	1121861.KB899915_gene1911	1.1e-165	534.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2TU6Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_2391455_4	1163617.SCD_n02494	5.41e-41	157.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
PYH1_k127_2391455_1	292415.Tbd_0111	3.117e-110	365.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,1KS80@119069|Hydrogenophilales	119069|Hydrogenophilales	M	MraW methylase family	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
PYH1_k127_2391455_6	1266925.JHVX01000005_gene1878	5.921e-23	101.0	COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria,373NV@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
PYH1_k127_239715_2	522306.CAP2UW1_0792	3.646e-34	135.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria	28216|Betaproteobacteria	H	synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
PYH1_k127_239715_0	1163617.SCD_n02796	1.249e-82	287.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria	28216|Betaproteobacteria	H	enzyme of heme biosynthesis	hemX	-	2.1.1.107,4.2.1.75	ko:K02496,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,HemX
PYH1_k127_239715_1	640081.Dsui_1599	4.669e-38	152.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,2KVAI@206389|Rhodocyclales	206389|Rhodocyclales	H	enzyme of heme biosynthesis	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N
PYH1_k127_243738_0	1150626.PHAMO_380065	0.0	1468.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,2JRE2@204441|Rhodospirillales	204441|Rhodospirillales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
PYH1_k127_243738_2	1163617.SCD_n02057	4.064e-38	146.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
PYH1_k127_243738_1	987059.RBXJA2T_19271	1.699e-50	190.0	COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,2VJS5@28216|Betaproteobacteria,1KJ5V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_2459039_6	1163617.SCD_n02012	1.15e-110	365.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_2459039_3	1205680.CAKO01000040_gene540	1.263e-153	508.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2JPM3@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
PYH1_k127_2459039_2	595537.Varpa_0285	1.168e-158	530.0	COG0654@1|root,COG0654@2|Bacteria,1MXEW@1224|Proteobacteria,2VIVN@28216|Betaproteobacteria,4AC5F@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM monooxygenase FAD-binding	-	-	1.14.13.218	ko:K20940	ko00405,ko01130,map00405,map01130	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
PYH1_k127_2459039_12	1168065.DOK_05570	1.517e-15	79.0	COG1937@1|root,COG1937@2|Bacteria,1NFTB@1224|Proteobacteria,1T084@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
PYH1_k127_2459039_5	1163617.SCD_n02696	1.678e-119	394.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
PYH1_k127_2459039_0	1163617.SCD_n02695	0.0	1455.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
PYH1_k127_2459039_9	1255043.TVNIR_1748	7.227e-40	152.0	COG2920@1|root,COG2920@2|Bacteria,1N3YM@1224|Proteobacteria	1224|Proteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
PYH1_k127_2459039_10	1353537.TP2_09990	1.422e-27	124.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2U06A@28211|Alphaproteobacteria,2XNRK@285107|Thioclava	28211|Alphaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH1_k127_2459039_4	1380394.JADL01000009_gene3323	2.868e-145	483.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,2JQ5F@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_2459039_8	331869.BAL199_15953	2.396e-96	327.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PYH1_k127_2459039_7	1532557.JL37_03775	7.681e-98	329.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJH2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_2459039_1	1288494.EBAPG3_31110	1.853e-190	604.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,3720W@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
PYH1_k127_2497616_9	1007105.PT7_1206	4.962e-80	293.0	COG0477@1|root,COG2814@2|Bacteria,1MX2P@1224|Proteobacteria,2VIIJ@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_2497616_6	388739.RSK20926_09357	2.11e-108	371.0	COG2114@1|root,COG2343@1|root,COG2114@2|Bacteria,COG2343@2|Bacteria,1MWHK@1224|Proteobacteria,2TR2J@28211|Alphaproteobacteria,2P4MN@2433|Roseobacter	28211|Alphaproteobacteria	T	protein conserved in bacteria	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,NTP_transf_9
PYH1_k127_2497616_4	522306.CAP2UW1_1272	9.631e-143	462.0	COG4313@1|root,COG4313@2|Bacteria,1PRCN@1224|Proteobacteria,2VQHT@28216|Betaproteobacteria,1KQK1@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
PYH1_k127_2497616_0	314278.NB231_01773	0.0	1215.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1WWMT@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
PYH1_k127_2497616_10	1300345.LF41_902	2.713e-54	207.0	COG2067@1|root,COG2067@2|Bacteria,1RJIQ@1224|Proteobacteria,1SAC1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2497616_8	1038869.AXAN01000013_gene6273	8.513e-96	338.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,1K3A8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	response regulator	basR_3	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH1_k127_2497616_1	640081.Dsui_0283	8.315e-285	882.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,2KUH8@206389|Rhodocyclales	206389|Rhodocyclales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
PYH1_k127_2497616_11	1131553.JIBI01000004_gene438	4.653e-47	171.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,373D1@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
PYH1_k127_2497616_5	1288494.EBAPG3_26530	3.613e-132	436.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,3726P@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
PYH1_k127_2497616_2	1454004.AW11_00534	6.263e-270	847.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
PYH1_k127_2497616_7	381666.H16_A3107	3.587e-104	346.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,1K3QR@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
PYH1_k127_2497616_3	1123367.C666_17620	9.919e-169	540.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,2KUCJ@206389|Rhodocyclales	206389|Rhodocyclales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
PYH1_k127_251373_28	1380386.JIAW01000039_gene1328	6.447e-31	143.0	COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
PYH1_k127_251373_24	398525.KB900701_gene4043	2.559e-52	214.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JUXC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MQ	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
PYH1_k127_251373_19	756067.MicvaDRAFT_5451	7.45e-85	321.0	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
PYH1_k127_251373_15	1430440.MGMSRv2_2433	3.913e-145	486.0	COG1566@1|root,COG1994@1|root,COG1566@2|Bacteria,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,2U0H8@28211|Alphaproteobacteria,2JR3V@204441|Rhodospirillales	204441|Rhodospirillales	M	Product type	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,HlyD_3
PYH1_k127_251373_25	1163407.UU7_12576	2.936e-42	162.0	2AD2S@1|root,312R0@2|Bacteria,1RDQX@1224|Proteobacteria,1S3Y6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_251373_8	795666.MW7_1226	5.406e-182	588.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VNJM@28216|Betaproteobacteria,1K04U@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Long-chain fatty acid--CoA ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,PP-binding
PYH1_k127_251373_11	1157708.KB907460_gene1481	2.572e-179	579.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,2VM1C@28216|Betaproteobacteria,4ABP0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dehydrogenase	-	-	1.2.1.81	ko:K15515	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
PYH1_k127_251373_17	543728.Vapar_3830	1.511e-106	354.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJBE@28216|Betaproteobacteria,4ACD2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_251373_0	1532557.JL37_06530	5.642e-266	831.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria,3T5NB@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	xsc	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_251373_31	1458357.BG58_12420	1.061e-05	54.0	COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,2VMTP@28216|Betaproteobacteria,1K22U@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_251373_14	1458357.BG58_12385	8.427e-146	465.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2VJ9E@28216|Betaproteobacteria,1K42E@119060|Burkholderiaceae	28216|Betaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
PYH1_k127_251373_1	666684.AfiDRAFT_3207	7.666e-241	753.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3JSS3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
PYH1_k127_251373_4	1411123.JQNH01000001_gene747	3.995e-193	608.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_251373_23	1411123.JQNH01000001_gene748	4.004e-64	224.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2UBPX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_251373_3	1411123.JQNH01000001_gene749	1.749e-203	650.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	TRAP-type mannitol chloroaromatic compound transport system large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
PYH1_k127_251373_9	1411123.JQNH01000001_gene3814	8.255e-180	570.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TV99@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the citrate synthase family	prpC	-	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PYH1_k127_251373_22	365046.Rta_37490	7.562e-65	228.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VRN7@28216|Betaproteobacteria,4ADWH@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_N
PYH1_k127_251373_18	1469245.JFBG01000083_gene236	9.009e-92	310.0	COG0280@1|root,COG0280@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria,1WW9Q@135613|Chromatiales	135613|Chromatiales	C	belongs to the CobB CobQ family	-	-	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
PYH1_k127_251373_13	1120977.JHUX01000005_gene2728	9.966e-166	535.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,3NITY@468|Moraxellaceae	1236|Gammaproteobacteria	C	Oxidative deamination of D-amino acids	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
PYH1_k127_251373_2	1144310.PMI07_000354	3.683e-205	677.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,4B7Q0@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH1_k127_251373_30	1304885.AUEY01000080_gene1034	4.605e-07	59.0	29AJY@1|root,2ZXJW@2|Bacteria,1P43F@1224|Proteobacteria,433B3@68525|delta/epsilon subdivisions,2WY93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_251373_16	573370.DMR_17700	7.336e-133	454.0	COG2114@1|root,COG2114@2|Bacteria,1R110@1224|Proteobacteria,42Z4S@68525|delta/epsilon subdivisions,2WUQ4@28221|Deltaproteobacteria,2MASB@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
PYH1_k127_251373_26	1000565.METUNv1_00458	1.69e-37	152.0	COG0589@1|root,COG0589@2|Bacteria,1NDDA@1224|Proteobacteria,2VUKE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH1_k127_251373_7	748247.AZKH_3413	3.698e-183	585.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VK75@28216|Betaproteobacteria	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
PYH1_k127_251373_12	1095769.CAHF01000006_gene1783	3.075e-169	565.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,472Y1@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	pcaF	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH1_k127_251373_6	1469245.JFBG01000009_gene562	1.776e-192	616.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,1RRJR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_251373_10	706587.Desti_4219	1.123e-179	572.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MQ5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Na+-transporting oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
PYH1_k127_251373_21	189753.AXAS01000012_gene4337	1.56e-77	270.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_251373_5	716928.AJQT01000082_gene2189	5.449e-193	618.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4BA4K@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_2,TPR_8
PYH1_k127_251373_20	713586.KB900536_gene2809	2.718e-84	285.0	COG2085@1|root,COG2085@2|Bacteria,1RCXR@1224|Proteobacteria,1S463@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NADP oxidoreductase, coenzyme f420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
PYH1_k127_2531447_0	640511.BC1002_0648	2.032e-72	256.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VIE1@28216|Betaproteobacteria,1K1WQ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyl transferase, family 4	wecA	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
PYH1_k127_2531447_1	1120999.JONM01000001_gene1244	4.958e-18	96.0	COG4254@1|root,COG4254@2|Bacteria,1NBPR@1224|Proteobacteria,2WAQS@28216|Betaproteobacteria,2KTMM@206351|Neisseriales	206351|Neisseriales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
PYH1_k127_2538506_1	1500257.JQNM01000014_gene2910	1.814e-129	422.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria,4BCRD@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
PYH1_k127_2538506_3	395963.Bind_2123	6.496e-69	237.0	COG2202@1|root,COG2202@2|Bacteria,1QV8B@1224|Proteobacteria,2TWQV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Single cache domain 3	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2
PYH1_k127_2538506_2	331869.BAL199_05104	2.281e-96	338.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,4BPBH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_2538506_4	1007105.PT7_2947	1.333e-17	89.0	COG4665@1|root,COG4665@2|Bacteria,1RK2F@1224|Proteobacteria	1224|Proteobacteria	Q	COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_2538506_0	1454004.AW11_03577	1.698e-170	543.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2VJXC@28216|Betaproteobacteria,1KQNM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_2538506_5	344747.PM8797T_32405	0.0001024	46.0	COG0300@1|root,COG0300@2|Bacteria,2IYV8@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH1_k127_2554688_2	1381123.AYOD01000011_gene2832	3.468e-38	147.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,2TSUI@28211|Alphaproteobacteria,43Q0U@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_2554688_1	438753.AZC_2112	1.508e-89	302.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,3F26F@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_2554688_0	1205680.CAKO01000040_gene1112	1.409e-99	330.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSCA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	amino acid	-	-	-	ko:K01996,ko:K11958	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	ABC_tran
PYH1_k127_255503_4	1089544.KB912942_gene5787	9.405e-55	197.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
PYH1_k127_255503_6	1120999.JONM01000003_gene2733	1.765e-17	93.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VSPR@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome	nosC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH1_k127_255503_3	882378.RBRH_02561	2.853e-60	229.0	COG1024@1|root,COG1024@2|Bacteria,1P3FI@1224|Proteobacteria,2VHYZ@28216|Betaproteobacteria,1K1J3@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaG2	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_255503_2	1097668.BYI23_C004530	5.541e-88	301.0	COG1414@1|root,COG1414@2|Bacteria,1R4WS@1224|Proteobacteria,2VQMK@28216|Betaproteobacteria,1KHY6@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
PYH1_k127_255503_1	1333856.L686_04915	7.641e-98	325.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,1S1FQ@1236|Gammaproteobacteria,1Z38K@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	IQ	KR domain	-	-	1.1.1.159,1.1.1.206	ko:K00076,ko:K08081	ko00121,ko00960,ko01100,ko01110,map00121,map00960,map01100,map01110	-	R02832	RC00144	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
PYH1_k127_255503_0	395494.Galf_1339	2.115e-107	369.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,44WDD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_255503_5	266264.Rmet_5414	8.123e-34	132.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,1K5IA@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the GMC oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
PYH1_k127_2592193_9	1095769.CAHF01000011_gene2600	4.375e-34	133.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,472P7@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Small MutS-related domain	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
PYH1_k127_2592193_8	1304883.KI912532_gene2957	2.87e-57	201.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KWKR@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
PYH1_k127_2592193_3	1175306.GWL_13330	4.423e-132	433.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,473E2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
PYH1_k127_2592193_6	358220.C380_09455	8.878e-98	343.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VMB3@28216|Betaproteobacteria,4ACE3@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	tsaC	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH1_k127_2592193_7	94624.Bpet2218	4.253e-70	254.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2VKF6@28216|Betaproteobacteria,3T35I@506|Alcaligenaceae	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
PYH1_k127_2592193_2	1217718.ALOU01000019_gene2721	2.759e-136	440.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,1K28G@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system	ugpC	-	3.6.3.20	ko:K05816,ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
PYH1_k127_2592193_5	614083.AWQR01000058_gene1510	6.957e-124	407.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2VICF@28216|Betaproteobacteria,4AAP2@80864|Comamonadaceae	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	ugpE	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
PYH1_k127_2592193_4	568706.BN118_1784	1.187e-130	422.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2VH0I@28216|Betaproteobacteria,3T261@506|Alcaligenaceae	28216|Betaproteobacteria	P	transporter permease	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
PYH1_k127_2592193_0	1268622.AVS7_03015	5.793e-171	565.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2VH0F@28216|Betaproteobacteria,4AA3S@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM extracellular solute-binding protein family 1	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
PYH1_k127_2592193_1	1207063.P24_14744	2.686e-140	458.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2TQKV@28211|Alphaproteobacteria,2JPHX@204441|Rhodospirillales	204441|Rhodospirillales	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
PYH1_k127_2592193_10	1156919.QWC_21589	1.203e-27	115.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VKAQ@28216|Betaproteobacteria,3T3RA@506|Alcaligenaceae	28216|Betaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH1_k127_2607057_1	1007105.PT7_1262	1.478e-151	481.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,3T1N5@506|Alcaligenaceae	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
PYH1_k127_2607057_0	1071679.BG57_08960	4.385e-298	947.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,1K1SA@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
PYH1_k127_2607057_3	640081.Dsui_1964	8.543e-49	175.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,2KWPS@206389|Rhodocyclales	206389|Rhodocyclales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
PYH1_k127_2607057_4	265072.Mfla_1996	1.373e-48	180.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,2KMY6@206350|Nitrosomonadales	206350|Nitrosomonadales	K	PFAM regulatory protein MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
PYH1_k127_2607057_2	1101195.Meth11DRAFT_2132	3.881e-55	196.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,2VK8Q@28216|Betaproteobacteria,2KNH4@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PYH1_k127_2608588_16	1038867.AXAY01000015_gene6941	1.17e-94	312.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2TUWC@28211|Alphaproteobacteria,3K2R0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	hpcG	-	-	ko:K02509	ko00350,ko01120,map00350,map01120	-	R04132,R06897	RC01615,RC02595	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
PYH1_k127_2608588_9	1349767.GJA_358	3.568e-116	377.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2VH95@28216|Betaproteobacteria,472S2@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	gstA	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_3
PYH1_k127_2608588_25	398525.KB900701_gene7751	1.493e-13	83.0	COG3637@1|root,COG3637@2|Bacteria,1MVJR@1224|Proteobacteria,2TY44@28211|Alphaproteobacteria,3JQM1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
PYH1_k127_2608588_18	1126627.BAWE01000002_gene856	3.816e-72	258.0	COG2984@1|root,COG2984@2|Bacteria,1R7C2@1224|Proteobacteria,2TZKG@28211|Alphaproteobacteria,3JXR0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
PYH1_k127_2608588_19	189753.AXAS01000012_gene4337	8.681e-62	228.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_2608588_6	1454004.AW11_00495	1.139e-159	529.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Glucose sorbosone	yliI	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
PYH1_k127_2608588_0	243231.GSU2758	0.0	2410.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42P3V@68525|delta/epsilon subdivisions,2WKWV@28221|Deltaproteobacteria,43TF0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
PYH1_k127_2608588_22	1121035.AUCH01000003_gene1185	4.881e-49	197.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,2KW7C@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
PYH1_k127_2608588_1	1454004.AW11_03712	7.224e-311	983.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2VJ68@28216|Betaproteobacteria,1KPN6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
PYH1_k127_2608588_21	243233.MCA0498	1.124e-50	187.0	COG4094@1|root,COG4094@2|Bacteria,1RDV6@1224|Proteobacteria,1SAUX@1236|Gammaproteobacteria,1XGC9@135618|Methylococcales	135618|Methylococcales	S	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
PYH1_k127_2608588_23	631454.N177_4032	2.341e-38	149.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH1_k127_2608588_5	365046.Rta_11920	1.034e-169	542.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,4AC8W@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PYH1_k127_2608588_12	640081.Dsui_0801	3.238e-108	373.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2VMGT@28216|Betaproteobacteria,2KVCS@206389|Rhodocyclales	206389|Rhodocyclales	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
PYH1_k127_2608588_4	1205680.CAKO01000038_gene1652	6.932e-170	563.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,2JPRU@204441|Rhodospirillales	204441|Rhodospirillales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
PYH1_k127_2608588_2	172088.AUGA01000013_gene7373	5.24e-256	796.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2UQJ2@28211|Alphaproteobacteria,3K2BQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	HpaB,HpaB_N
PYH1_k127_2608588_15	439235.Dalk_1988	2.608e-98	328.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,43AR1@68525|delta/epsilon subdivisions,2X64Y@28221|Deltaproteobacteria,2MNAT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_2608588_14	439235.Dalk_1989	2.293e-102	354.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,42S2H@68525|delta/epsilon subdivisions,2WNMT@28221|Deltaproteobacteria,2MKDU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_2608588_17	439235.Dalk_4902	2.873e-89	317.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,43AR2@68525|delta/epsilon subdivisions,2X64Z@28221|Deltaproteobacteria,2MKIP@213118|Desulfobacterales	1224|Proteobacteria	E	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_2608588_11	439235.Dalk_1991	8.35e-112	368.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,42RHF@68525|delta/epsilon subdivisions,2WNRC@28221|Deltaproteobacteria,2MK7I@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_2608588_8	439235.Dalk_1992	9.48e-144	470.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,42TEX@68525|delta/epsilon subdivisions,2WPG8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_2608588_3	1380394.JADL01000011_gene3905	7.318e-222	702.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JPPV@204441|Rhodospirillales	204441|Rhodospirillales	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
PYH1_k127_2608588_10	1502852.FG94_03528	1.989e-115	379.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,472CI@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
PYH1_k127_2608588_20	398578.Daci_5624	5.633e-56	217.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2VMQB@28216|Betaproteobacteria,4AAQF@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_2608588_13	338969.Rfer_0960	2.2e-104	356.0	COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_2608588_7	640081.Dsui_1563	6.127e-147	475.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,2KUG8@206389|Rhodocyclales	206389|Rhodocyclales	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
PYH1_k127_2608588_24	1184267.A11Q_1612	1.542e-34	134.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,430NN@68525|delta/epsilon subdivisions,2MT6T@213481|Bdellovibrionales,2WVYS@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
PYH1_k127_2608588_26	62928.azo3379	2.312e-09	59.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,2VIZ8@28216|Betaproteobacteria,2KVMB@206389|Rhodocyclales	206389|Rhodocyclales	S	Beta-lactamase	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
PYH1_k127_2611173_1	472759.Nhal_0828	4.71e-55	209.0	COG0515@1|root,COG0515@2|Bacteria,1QXK0@1224|Proteobacteria,1T3DE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	Pkinase,TIR_2
PYH1_k127_2611173_0	713586.KB900536_gene1611	3.85e-82	286.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	cyaB	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,MASE2
PYH1_k127_2611173_3	56780.SYN_00227	3.832e-18	87.0	COG2198@1|root,COG2198@2|Bacteria,1NJUT@1224|Proteobacteria,42WXF@68525|delta/epsilon subdivisions,2WSRZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	(Hpt) domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
PYH1_k127_2611173_2	292415.Tbd_0828	5.381e-34	132.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,1KS3D@119069|Hydrogenophilales	28216|Betaproteobacteria	L	Bacterial DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
PYH1_k127_2614447_2	713587.THITH_03495	3.653e-212	670.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1WX9G@135613|Chromatiales	135613|Chromatiales	C	PFAM Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
PYH1_k127_2614447_4	1123392.AQWL01000008_gene1153	2.117e-142	467.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2VV9S@28216|Betaproteobacteria,1KSCV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
PYH1_k127_2614447_6	1163617.SCD_n01882	6.957e-88	310.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
PYH1_k127_2614447_1	1163617.SCD_n01883	0.0	1058.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
PYH1_k127_2614447_3	1123393.KB891317_gene2468	1.435e-209	657.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,2VUBQ@28216|Betaproteobacteria,1KSSF@119069|Hydrogenophilales	119069|Hydrogenophilales	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
PYH1_k127_2614447_0	204773.HEAR3342	0.0	1560.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2W94M@28216|Betaproteobacteria,47825@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
PYH1_k127_2614447_5	580332.Slit_1710	2.042e-132	453.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,44W9R@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4
PYH1_k127_2614447_7	667632.KB890175_gene4130	7.561e-55	197.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria,1K58I@119060|Burkholderiaceae	28216|Betaproteobacteria	S	DMSO reductase	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
PYH1_k127_2658353_4	1304883.KI912532_gene1925	6.379e-35	136.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,2KUFS@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	-	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
PYH1_k127_2658353_5	713586.KB900536_gene575	1.061e-20	96.0	2EJUZ@1|root,33DJM@2|Bacteria,1NIYD@1224|Proteobacteria,1SGV4@1236|Gammaproteobacteria,1WZJR@135613|Chromatiales	135613|Chromatiales	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
PYH1_k127_2658353_3	153948.NAL212_3012	8.525e-43	171.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,373A7@32003|Nitrosomonadales	28216|Betaproteobacteria	H	diol metabolic process	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
PYH1_k127_2658353_0	1131553.JIBI01000016_gene616	6.559e-153	497.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,372MW@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM Peptidase M48	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
PYH1_k127_2658353_2	1121004.ATVC01000025_gene214	1.539e-77	263.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,2KPCE@206351|Neisseriales	206351|Neisseriales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
PYH1_k127_2658353_1	864069.MicloDRAFT_00015930	3.038e-112	376.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,2TSIN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
PYH1_k127_2665722_1	68199.JNZO01000001_gene1148	1.418e-77	267.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
PYH1_k127_2665722_2	595537.Varpa_1966	1.269e-55	201.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,2VJR8@28216|Betaproteobacteria,4AABW@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PYH1_k127_2665722_0	1366050.N234_06430	7.581e-143	459.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2VJJQ@28216|Betaproteobacteria,1K237@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
PYH1_k127_2706594_18	582744.Msip34_2828	2.99e-08	60.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,2KM2S@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
PYH1_k127_2706594_16	76114.ebB89	8.184e-27	113.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,2KX78@206389|Rhodocyclales	206389|Rhodocyclales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
PYH1_k127_2706594_19	243365.CV_4406	2.69e-06	55.0	COG0594@1|root,COG0594@2|Bacteria,1PVTI@1224|Proteobacteria,2VW57@28216|Betaproteobacteria,2KU22@206351|Neisseriales	206351|Neisseriales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
PYH1_k127_2706594_17	1286631.X805_25270	8.664e-13	69.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria,1KMIM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
PYH1_k127_2706594_6	76114.ebA2846	1.357e-179	573.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,2KUSQ@206389|Rhodocyclales	206389|Rhodocyclales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
PYH1_k127_2706594_7	1144342.PMI40_04395	1.39e-132	432.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,47303@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
PYH1_k127_2706594_1	1288494.EBAPG3_7950	0.0	1215.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,3725J@32003|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
PYH1_k127_2706594_2	1038869.AXAN01000006_gene919	0.0	1110.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,1K0Y7@119060|Burkholderiaceae	28216|Betaproteobacteria	L	dna topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
PYH1_k127_2706594_15	76114.ebA2962	1.804e-31	131.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,2KWJJ@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
PYH1_k127_2706594_10	1454004.AW11_02680	1.912e-116	385.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,1KQIR@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	LU	DNA recombination-mediator protein A	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
PYH1_k127_2706594_11	1163617.SCD_n00008	1.638e-105	355.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM
PYH1_k127_2706594_13	1123393.KB891332_gene2764	1.037e-62	219.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,1KRYP@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
PYH1_k127_2706594_12	85643.Tmz1t_0094	2.501e-103	344.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,2KVNV@206389|Rhodocyclales	206389|Rhodocyclales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
PYH1_k127_2706594_8	640081.Dsui_0812	4.948e-131	436.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,2KV06@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
PYH1_k127_2706594_14	1454004.AW11_02688	1.035e-47	181.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,1KQVH@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
PYH1_k127_2706594_3	640081.Dsui_0810	2.216e-213	693.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,2KV2P@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PYH1_k127_2706594_9	292415.Tbd_0019	2.718e-125	414.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,1KRMI@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
PYH1_k127_2706594_5	580332.Slit_2942	1.864e-194	620.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria,44W83@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
PYH1_k127_2706594_4	1131553.JIBI01000071_gene2157	4.211e-206	653.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,3728D@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
PYH1_k127_2706594_0	580332.Slit_0060	0.0	1673.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,44V3A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Vitamin B12 dependent methionine synthase activation region	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
PYH1_k127_2708334_5	1266925.JHVX01000008_gene368	2.44e-176	565.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,371S5@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
PYH1_k127_2708334_6	1348657.M622_18290	3.462e-146	477.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,2KVKC@206389|Rhodocyclales	206389|Rhodocyclales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
PYH1_k127_2708334_15	305700.B447_02541	1.087e-77	276.0	COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,2VM18@28216|Betaproteobacteria,2KZHC@206389|Rhodocyclales	206389|Rhodocyclales	S	Pfam:AmoA	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
PYH1_k127_2708334_1	1123354.AUDR01000001_gene2029	3.101e-296	918.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
PYH1_k127_2708334_4	768066.HELO_1855	1.534e-199	630.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XH5I@135619|Oceanospirillales	135619|Oceanospirillales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
PYH1_k127_2708334_21	1125971.ASJB01000083_gene2199	6.601e-47	184.0	COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4DXRA@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_2708334_0	279714.FuraDRAFT_0132	2.41e-300	934.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,2KPX6@206351|Neisseriales	206351|Neisseriales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
PYH1_k127_2708334_17	1123392.AQWL01000013_gene2371	6.419e-59	212.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,1KRP8@119069|Hydrogenophilales	119069|Hydrogenophilales	J	rRNA small subunit methyltransferase G	-	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
PYH1_k127_2708334_11	1288494.EBAPG3_8040	4.519e-112	368.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,371Z8@32003|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
PYH1_k127_2708334_13	1123367.C666_13735	1.296e-100	335.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,2KU8M@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the ParB family	spoOJ	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
PYH1_k127_2708334_26	1266925.JHVX01000005_gene1938	3.197e-18	93.0	COG3312@1|root,COG3312@2|Bacteria,1R3CS@1224|Proteobacteria,2WIGV@28216|Betaproteobacteria,374P5@32003|Nitrosomonadales	28216|Betaproteobacteria	C	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
PYH1_k127_2708334_10	323848.Nmul_A0304	9.746e-129	415.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,371W5@32003|Nitrosomonadales	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
PYH1_k127_2708334_23	323848.Nmul_A0305	7.629e-38	143.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,373AG@32003|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
PYH1_k127_2708334_20	1266925.JHVX01000005_gene1935	4.236e-49	180.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,372ZX@32003|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
PYH1_k127_2708334_22	323848.Nmul_A0307	3.036e-38	156.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,3737S@32003|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
PYH1_k127_2708334_2	667632.KB890176_gene4611	8.03e-277	857.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,1K1JD@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
PYH1_k127_2708334_9	261292.Nit79A3_0372	6.73e-133	428.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,371MG@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
PYH1_k127_2708334_3	887898.HMPREF0551_2052	1.824e-259	804.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,1K2Y1@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
PYH1_k127_2708334_19	75379.Tint_2753	8.721e-55	195.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,1KKT3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
PYH1_k127_2708334_8	43989.cce_3035	8.915e-135	469.0	COG2931@1|root,COG3209@1|root,COG5295@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG5295@2|Bacteria,1GQ6Z@1117|Cyanobacteria,3KK0X@43988|Cyanothece	2|Bacteria	Q	Domain of unknown function (DUF4347)	tek	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,Cadherin_3,HemolysinCabind,Hint_2,RHS_repeat
PYH1_k127_2708334_25	91464.S7335_5095	1.13e-22	115.0	COG2931@1|root,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria,1H0CR@1129|Synechococcus	1117|Cyanobacteria	Q	Q COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,FG-GAP,HemolysinCabind
PYH1_k127_2708334_16	264198.Reut_A0221	9.76e-68	236.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,1K2SD@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	gst8	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_C_4,GST_N_3
PYH1_k127_2708334_7	580332.Slit_1619	1.494e-140	459.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
PYH1_k127_2708334_18	396588.Tgr7_1268	1.934e-57	207.0	COG2181@1|root,COG2181@2|Bacteria,1QQCT@1224|Proteobacteria,1S05R@1236|Gammaproteobacteria,1WXBW@135613|Chromatiales	135613|Chromatiales	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2708334_12	1415630.U771_29140	6.6e-106	367.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Inner membrane protein involved in colicin E2 resistance	creD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
PYH1_k127_2708334_14	349521.HCH_04353	8.041e-98	325.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,1XNQA@135619|Oceanospirillales	135619|Oceanospirillales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH1_k127_2708334_27	1121013.P873_03645	0.0002561	51.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,1X4YC@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PYH1_k127_2741432_4	397945.Aave_0163	8.425e-54	194.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2VIKU@28216|Betaproteobacteria,4AB6Z@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH1_k127_2741432_2	365046.Rta_32510	1.927e-136	441.0	COG1638@1|root,COG1638@2|Bacteria,1NTFS@1224|Proteobacteria,2VM5I@28216|Betaproteobacteria,4AGQZ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_2741432_3	365046.Rta_32500	3.192e-57	218.0	COG3090@1|root,COG3090@2|Bacteria,1RA8Q@1224|Proteobacteria,2VWND@28216|Betaproteobacteria,4AGGN@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_2741432_1	365046.Rta_32490	1.739e-197	623.0	COG4664@1|root,COG4664@2|Bacteria,1QU8F@1224|Proteobacteria,2VKVK@28216|Betaproteobacteria,4AGQC@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_2741432_0	1123504.JQKD01000007_gene3331	1.647e-249	782.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
PYH1_k127_275043_0	62928.azo2209	3.764e-110	361.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales	206389|Rhodocyclales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
PYH1_k127_275043_1	1266925.JHVX01000011_gene1486	2.209e-86	291.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,371NN@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
PYH1_k127_275043_2	365046.Rta_19360	1.775e-72	249.0	COG0723@1|root,COG0723@2|Bacteria,1MZ7A@1224|Proteobacteria,2VVI5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	plastoquinol--plastocyanin reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2752900_16	1267533.KB906737_gene1838	1.684e-57	205.0	COG0520@1|root,COG0520@2|Bacteria,3Y3UN@57723|Acidobacteria,2JK05@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
PYH1_k127_2752900_2	596153.Alide_2901	5.63e-192	606.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VI1V@28216|Betaproteobacteria,4ABKZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_2752900_3	1122604.JONR01000036_gene3804	1.29e-159	513.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,1RNB4@1236|Gammaproteobacteria,1X3BR@135614|Xanthomonadales	135614|Xanthomonadales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
PYH1_k127_2752900_17	1279019.ARQK01000057_gene803	1.064e-48	181.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1WYB4@135613|Chromatiales	135613|Chromatiales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
PYH1_k127_2752900_20	395493.BegalDRAFT_1514	1.117e-14	76.0	COG5481@1|root,COG5481@2|Bacteria	2|Bacteria	S	small protein containing a coiled-coil domain	MA20_03740	-	-	-	-	-	-	-	-	-	-	-	DUF465
PYH1_k127_2752900_15	391615.ABSJ01000026_gene121	2.492e-70	250.0	2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria,1J8X1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2752900_12	1380394.JADL01000003_gene5080	2.67e-83	287.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,2JRVV@204441|Rhodospirillales	204441|Rhodospirillales	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
PYH1_k127_2752900_0	1040989.AWZU01000028_gene3006	1.662e-222	705.0	COG3573@1|root,COG3573@2|Bacteria,1MVX8@1224|Proteobacteria,2TVKJ@28211|Alphaproteobacteria,3JSJV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	FAD binding domain	MA20_22130	-	-	ko:K07077	-	-	-	-	ko00000	-	-	-	FAD_binding_2
PYH1_k127_2752900_1	414684.RC1_0235	1.437e-220	736.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2JPQC@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_2752900_14	497321.C664_10657	5.335e-79	284.0	COG3568@1|root,COG3568@2|Bacteria,1R99W@1224|Proteobacteria,2VPVB@28216|Betaproteobacteria,2KUNI@206389|Rhodocyclales	206389|Rhodocyclales	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
PYH1_k127_2752900_18	1487953.JMKF01000072_gene3478	1.996e-35	141.0	COG4446@1|root,COG4446@2|Bacteria,1G6W2@1117|Cyanobacteria,1HBIQ@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG4446 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
PYH1_k127_2752900_7	1071679.BG57_22275	5.949e-123	398.0	COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,2VIMS@28216|Betaproteobacteria,1K0A8@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA15	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH1_k127_2752900_5	1122604.JONR01000004_gene881	1.097e-126	411.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,1RP4C@1236|Gammaproteobacteria,1X3HD@135614|Xanthomonadales	135614|Xanthomonadales	S	Alpha beta hydrolase	dhaA	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
PYH1_k127_2752900_9	221288.JH992901_gene1226	5.352e-111	402.0	COG1171@1|root,COG1171@2|Bacteria,1G22X@1117|Cyanobacteria,1JHYB@1189|Stigonemataceae	1117|Cyanobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH1_k127_2752900_8	640081.Dsui_0513	4.269e-113	389.0	COG2199@1|root,COG2199@2|Bacteria,1QTT5@1224|Proteobacteria,2VKM3@28216|Betaproteobacteria,2KY09@206389|Rhodocyclales	206389|Rhodocyclales	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
PYH1_k127_2752900_4	760117.JN27_13275	8.145e-142	457.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VHCB@28216|Betaproteobacteria,473CI@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NADPH quinone oxidoreductase	qor1	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_2752900_19	1231190.NA8A_10738	5.23e-19	94.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2UG8Q@28211|Alphaproteobacteria,43QQ3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
PYH1_k127_2752900_13	314285.KT71_14279	4.926e-80	273.0	COG3917@1|root,COG3917@2|Bacteria,1MV6E@1224|Proteobacteria,1SMQ0@1236|Gammaproteobacteria,1J8HD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
PYH1_k127_2752900_10	296591.Bpro_2639	2.334e-97	327.0	COG1917@1|root,COG1917@2|Bacteria,1RH0Y@1224|Proteobacteria,2VWWA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2752900_11	1496688.ER33_11550	1.522e-83	282.0	28PFD@1|root,2ZC6I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2752900_6	402881.Plav_0450	4.394e-126	409.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2U149@28211|Alphaproteobacteria,1JQM5@119043|Rhodobiaceae	28211|Alphaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	MA20_16350	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_2766348_4	1458357.BG58_09880	6.897e-41	155.0	2E56P@1|root,32ZZD@2|Bacteria,1PYIM@1224|Proteobacteria,2W0YN@28216|Betaproteobacteria,1KATT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3302
PYH1_k127_2766348_3	1458357.BG58_09875	7.434e-112	382.0	COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,2VZSW@28216|Betaproteobacteria,1K5Z2@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
PYH1_k127_2766348_1	1458357.BG58_09870	1.779e-140	460.0	COG1538@1|root,COG1538@2|Bacteria,1REC6@1224|Proteobacteria,2VZ9S@28216|Betaproteobacteria,1KBKV@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
PYH1_k127_2766348_2	1232410.KI421426_gene1459	2.046e-125	419.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42PGM@68525|delta/epsilon subdivisions,2X5J8@28221|Deltaproteobacteria,43SW4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PYH1_k127_2766348_0	398767.Glov_1392	0.0	1241.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,43U04@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
PYH1_k127_2766348_5	1232410.KI421426_gene1457	5.558e-25	106.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,43THY@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
PYH1_k127_2771658_1	713587.THITH_03765	1.436e-06	56.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,1S5V4@1236|Gammaproteobacteria,1WYBY@135613|Chromatiales	135613|Chromatiales	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
PYH1_k127_2771658_0	330214.NIDE0660	3.519e-142	459.0	COG1373@1|root,COG1373@2|Bacteria,3J14P@40117|Nitrospirae	40117|Nitrospirae	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PYH1_k127_2806360_0	1163617.SCD_n02127	3.697e-295	971.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
PYH1_k127_2806360_6	640081.Dsui_3491	4.008e-27	128.0	COG4726@1|root,COG4726@2|Bacteria,1N9CE@1224|Proteobacteria,2VWPP@28216|Betaproteobacteria,2KXMR@206389|Rhodocyclales	206389|Rhodocyclales	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2806360_2	375286.mma_3357	3.767e-51	203.0	COG4795@1|root,COG4795@2|Bacteria	2|Bacteria	U	General secretion pathway protein	ppdB	-	-	ko:K02459,ko:K02672,ko:K02680	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	N_methyl
PYH1_k127_2806360_7	1163617.SCD_n02124	1.107e-22	110.0	COG4967@1|root,COG4967@2|Bacteria,1N7AC@1224|Proteobacteria,2VW8B@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
PYH1_k127_2806360_3	1454004.AW11_01626	1.416e-40	165.0	COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VWAB@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
PYH1_k127_2806360_5	85643.Tmz1t_2663	1.939e-28	123.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,2KX3T@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
PYH1_k127_2806360_4	204773.HEAR2989	1.716e-36	146.0	2DP0A@1|root,3300Q@2|Bacteria,1N78Y@1224|Proteobacteria,2VVZ5@28216|Betaproteobacteria,474AI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
PYH1_k127_2806360_1	76114.ebA4111	4.679e-62	226.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,2KW3H@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
PYH1_k127_2806360_8	1453503.AU05_23405	8.581e-06	51.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1YFB9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
PYH1_k127_2820987_7	1218075.BAYA01000009_gene3174	6.057e-40	166.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VP68@28216|Betaproteobacteria,1K1EY@119060|Burkholderiaceae	28216|Betaproteobacteria	C	luciferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
PYH1_k127_2820987_11	641491.DND132_1605	1.224e-07	64.0	COG0477@1|root,COG2814@2|Bacteria,1MX2Q@1224|Proteobacteria,42QJ1@68525|delta/epsilon subdivisions,2WKZ2@28221|Deltaproteobacteria,2M8KG@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
PYH1_k127_2820987_6	1112274.KI911560_gene1290	1.048e-60	221.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2VSC6@28216|Betaproteobacteria,2KMZR@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
PYH1_k127_2820987_12	1304275.C41B8_06502	4.347e-07	62.0	2C99D@1|root,2Z7Y8@2|Bacteria,1R5JY@1224|Proteobacteria,1SI3Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DNA-sulfur modification-associated	-	-	-	-	-	-	-	-	-	-	-	-	DndB
PYH1_k127_2820987_2	1128421.JAGA01000002_gene335	3.346e-124	414.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
PYH1_k127_2820987_0	391735.Veis_4805	2.343e-150	489.0	COG1804@1|root,COG1804@2|Bacteria,1MU4A@1224|Proteobacteria,2VKDA@28216|Betaproteobacteria,4AA04@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH1_k127_2820987_5	204773.HEAR0260	2.837e-63	226.0	COG3971@1|root,COG3971@2|Bacteria,1RGHI@1224|Proteobacteria,2VRTF@28216|Betaproteobacteria,473R4@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	2-keto-4-pentenoate hydratase	mhpD	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
PYH1_k127_2820987_10	267608.RSc1422	5.109e-14	78.0	COG1585@1|root,COG1585@2|Bacteria,1N474@1224|Proteobacteria,2VWDX@28216|Betaproteobacteria,1K7AI@119060|Burkholderiaceae	28216|Betaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
PYH1_k127_2820987_3	556268.OFAG_00209	3.685e-115	399.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,47242@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	C-terminal region of band_7	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
PYH1_k127_2820987_8	1380394.JADL01000001_gene2775	7.799e-34	134.0	COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,2U4YP@28211|Alphaproteobacteria,2JU5E@204441|Rhodospirillales	204441|Rhodospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH1_k127_2820987_4	864051.BurJ1DRAFT_3307	7.094e-74	259.0	COG0599@1|root,COG2146@1|root,COG0599@2|Bacteria,COG2146@2|Bacteria,1RCCG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Rieske
PYH1_k127_2820987_1	365046.Rta_15440	6.992e-130	422.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP9X@28216|Betaproteobacteria,4AA72@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_2820987_9	246197.MXAN_5515	3.974e-14	73.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WM9S@28221|Deltaproteobacteria,2YZVS@29|Myxococcales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
PYH1_k127_2892970_2	1095769.CAHF01000022_gene424	7.358e-13	74.0	2AG99@1|root,316ES@2|Bacteria,1PXFW@1224|Proteobacteria,2WCW3@28216|Betaproteobacteria,478AU@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2892970_3	1144319.PMI16_01874	2.119e-12	78.0	2E3Q5@1|root,32YN4@2|Bacteria,1NA23@1224|Proteobacteria,2VVXW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilN
PYH1_k127_2892970_1	1095769.CAHF01000022_gene426	1.599e-20	100.0	COG3167@1|root,COG3167@2|Bacteria,1N685@1224|Proteobacteria,2VU7Q@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	carbon utilization	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2892970_0	1095769.CAHF01000022_gene428	1.819e-179	580.0	COG4796@1|root,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria,472RY@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N
PYH1_k127_2898879_13	580332.Slit_2287	5.914e-19	94.0	2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria,44WH3@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2898879_11	1163617.SCD_n01245	1.462e-88	301.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
PYH1_k127_2898879_7	1163617.SCD_n01244	1.705e-117	403.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	(Lipo)protein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
PYH1_k127_2898879_4	62928.azo1096	1.832e-134	434.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,2KUG2@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
PYH1_k127_2898879_12	1121033.AUCF01000015_gene1484	5.762e-52	197.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,2TY3M@28211|Alphaproteobacteria,2JYYN@204441|Rhodospirillales	204441|Rhodospirillales	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2898879_1	1283300.ATXB01000001_gene380	6.641e-233	760.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,1XE60@135618|Methylococcales	135618|Methylococcales	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
PYH1_k127_2898879_3	1458357.BG58_13295	1.352e-215	680.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,1K51A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3,SLT
PYH1_k127_2898879_2	395964.KE386496_gene2906	2.156e-222	698.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,3NCCR@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
PYH1_k127_2898879_0	316057.RPD_2516	0.0	1379.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,3JVKE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130,ko:K01138	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
PYH1_k127_2898879_8	1265503.KB905160_gene2975	2.472e-116	382.0	COG4313@1|root,COG4313@2|Bacteria,1PC95@1224|Proteobacteria,1RZJZ@1236|Gammaproteobacteria,2Q8AT@267889|Colwelliaceae	1236|Gammaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
PYH1_k127_2898879_9	269799.Gmet_2726	1.045e-110	364.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,42N0U@68525|delta/epsilon subdivisions,2WJH3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
PYH1_k127_2898879_5	640081.Dsui_1230	1.188e-124	426.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,2KVEI@206389|Rhodocyclales	206389|Rhodocyclales	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
PYH1_k127_2898879_10	1163617.SCD_n02166	7.841e-109	382.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
PYH1_k127_2898879_6	221288.JH992901_gene4253	5.306e-122	406.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,1JHRW@1189|Stigonemataceae	1117|Cyanobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
PYH1_k127_2906928_8	1492922.GY26_03080	1.911e-23	102.0	COG0789@1|root,COG0789@2|Bacteria,1RJIK@1224|Proteobacteria,1TA28@1236|Gammaproteobacteria,1JBJE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
PYH1_k127_2906928_2	365044.Pnap_1308	1.099e-201	639.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,2VKVU@28216|Betaproteobacteria,4AA8S@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
PYH1_k127_2906928_7	748247.AZKH_1814	1.416e-30	130.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,2KX94@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
PYH1_k127_2906928_0	748247.AZKH_p0501	0.0	1144.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,2KUM5@206389|Rhodocyclales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
PYH1_k127_2906928_5	1502851.FG93_03189	9.38e-104	355.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria,3JU3K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	alcohol dehydrogenase	-	GO:0001505,GO:0003008,GO:0003674,GO:0003824,GO:0004022,GO:0004552,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0007610,GO:0007611,GO:0007612,GO:0007632,GO:0008150,GO:0008152,GO:0008306,GO:0008542,GO:0009314,GO:0009416,GO:0009628,GO:0016491,GO:0016614,GO:0016616,GO:0016651,GO:0016657,GO:0019222,GO:0031323,GO:0031399,GO:0032268,GO:0032501,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051171,GO:0051246,GO:0051903,GO:0055114,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080007,GO:0080090,GO:0080164,GO:1901615,GO:2000169,GO:2000377	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_2906928_9	1163617.SCD_n02150	6.327e-15	82.0	COG2863@1|root,COG2863@2|Bacteria	2|Bacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
PYH1_k127_2906928_10	243231.GSU0710	0.0003577	53.0	2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,431EY@68525|delta/epsilon subdivisions,2WWFV@28221|Deltaproteobacteria,43VKI@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2906928_3	1380394.JADL01000002_gene1394	1.045e-192	610.0	COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria,2JT4J@204441|Rhodospirillales	204441|Rhodospirillales	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
PYH1_k127_2906928_4	1449353.JQMQ01000004_gene5932	7.671e-112	371.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,2NHIR@228398|Streptacidiphilus	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
PYH1_k127_2906928_6	381666.H16_B1793	1.036e-83	291.0	COG3181@1|root,COG3181@2|Bacteria,1N4MC@1224|Proteobacteria,2VKJS@28216|Betaproteobacteria,1KCQ9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_2906928_1	323261.Noc_2095	1.399e-237	745.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1WWS1@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
PYH1_k127_2920995_1	1454004.AW11_03226	2.021e-15	89.0	COG2982@1|root,COG2982@2|Bacteria,1RD61@1224|Proteobacteria,2VS09@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
PYH1_k127_2920995_0	62928.azo2158	1.799e-91	330.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KVJB@206389|Rhodocyclales	206389|Rhodocyclales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
PYH1_k127_2948690_0	1163617.SCD_n02088	0.0	1442.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
PYH1_k127_2948690_1	1123393.KB891317_gene2279	8.059e-74	254.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,1KRM8@119069|Hydrogenophilales	119069|Hydrogenophilales	V	Ami_2	-	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
PYH1_k127_2948690_2	1408473.JHXO01000008_gene2765	7.828e-05	46.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMCJ@200643|Bacteroidia	976|Bacteroidetes	T	Sigma-54 interaction domain protein	zraR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
PYH1_k127_2968146_7	1163617.SCD_n00093	3.389e-20	98.0	2DPC5@1|root,331GN@2|Bacteria,1NCRC@1224|Proteobacteria,2VVUT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
PYH1_k127_2968146_3	1123229.AUBC01000016_gene4264	7.397e-104	341.0	COG0461@1|root,COG0461@2|Bacteria,1MVP7@1224|Proteobacteria,2TTSB@28211|Alphaproteobacteria,3JRPV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
PYH1_k127_2968146_2	1131553.JIBI01000004_gene393	2.415e-114	385.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,372JW@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Exodeoxyribonuclease III xth	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
PYH1_k127_2968146_6	159087.Daro_0127	1.749e-23	106.0	2CKHZ@1|root,332B5@2|Bacteria,1NAZ6@1224|Proteobacteria,2VW0U@28216|Betaproteobacteria,2KXBX@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_2968146_8	1123392.AQWL01000007_gene1017	1.758e-17	87.0	COG5393@1|root,COG5393@2|Bacteria,1NDFU@1224|Proteobacteria,2VX3I@28216|Betaproteobacteria,1KRW7@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
PYH1_k127_2968146_5	395494.Galf_2212	7.869e-36	141.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,44WIE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
PYH1_k127_2968146_1	1131269.AQVV01000018_gene1913	8.581e-154	497.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	ampG	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K08218,ko:K08223	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25,2.A.1.35	-	iAPECO1_1312.APECO1_1578,iECOK1_1307.ECOK1_0413,iECS88_1305.ECS88_0429,iLF82_1304.LF82_0088,iNRG857_1313.NRG857_02040,iPC815.YPO3162,iUMN146_1321.UM146_15195,iUTI89_1310.UTI89_C0457	MFS_1
PYH1_k127_2968146_4	697282.Mettu_0209	1.146e-39	164.0	COG3209@1|root,COG4447@1|root,COG3209@2|Bacteria,COG4447@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1XGAS@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
PYH1_k127_2968146_0	261292.Nit79A3_3318	3.355e-228	751.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VMY9@28216|Betaproteobacteria,371V4@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Insecticidal toxin complex protein TcaC	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
PYH1_k127_3009423_5	1144319.PMI16_01439	3.199e-19	90.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,474Y0@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
PYH1_k127_3009423_0	1235457.C404_13630	2.882e-158	506.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,1K22K@119060|Burkholderiaceae	28216|Betaproteobacteria	P	rieske 2fe-2s	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
PYH1_k127_3009423_2	1123367.C666_06175	1.573e-88	314.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,2KVPB@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	tst	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
PYH1_k127_3009423_3	880526.KE386488_gene1053	2.745e-77	272.0	COG2267@1|root,COG2267@2|Bacteria,4NHI2@976|Bacteroidetes,2FNPW@200643|Bacteroidia,22V0W@171550|Rikenellaceae	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
PYH1_k127_3009423_6	497321.C664_03000	1.28e-14	74.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,2KUCX@206389|Rhodocyclales	206389|Rhodocyclales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
PYH1_k127_3009423_1	1485544.JQKP01000003_gene111	8.252e-120	392.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,44VK1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
PYH1_k127_3009423_4	323848.Nmul_A2531	7.054e-39	151.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,3735C@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
PYH1_k127_3023443_7	1288494.EBAPG3_17950	6.323e-17	81.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,3734W@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
PYH1_k127_3023443_5	1163617.SCD_n00061	7.949e-62	222.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
PYH1_k127_3023443_0	1121035.AUCH01000006_gene686	6.832e-226	717.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,2KU6W@206389|Rhodocyclales	206389|Rhodocyclales	J	ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
PYH1_k127_3023443_1	479434.Sthe_3255	2.658e-180	598.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	200795|Chloroflexi	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH1_k127_3023443_4	114615.BRADO4672	1.736e-88	312.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,3JSMD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	MA20_26500	-	-	-	-	-	-	-	-	-	-	-	CMD
PYH1_k127_3023443_2	1095769.CAHF01000021_gene892	6.865e-142	456.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,472N8@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	tctC4	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_3023443_6	1095769.CAHF01000005_gene1570	1.148e-44	168.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,476ER@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH1_k127_3023443_3	85643.Tmz1t_0574	3.409e-93	313.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,2KUJJ@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
PYH1_k127_3057401_2	743719.PaelaDRAFT_3105	5.275e-45	170.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,26SC6@186822|Paenibacillaceae	91061|Bacilli	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
PYH1_k127_3057401_1	1392838.AWNM01000063_gene4111	1.677e-94	320.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2VKKP@28216|Betaproteobacteria,3T2PC@506|Alcaligenaceae	28216|Betaproteobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
PYH1_k127_3057401_0	1380394.JADL01000011_gene4046	7.456e-142	461.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JQUF@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
PYH1_k127_3057401_3	90814.KL370891_gene747	1.11e-13	74.0	2BZMS@1|root,32Z9B@2|Bacteria,1NCFD@1224|Proteobacteria,1SPFN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
PYH1_k127_3058695_1	1163617.SCD_n02630	2.671e-76	261.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
PYH1_k127_3058695_0	1163617.SCD_n02625	6.176e-149	490.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria	28216|Betaproteobacteria	H	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
PYH1_k127_3058695_2	1163617.SCD_n02624	1.245e-17	98.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,2VUIR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
PYH1_k127_3066687_1	640081.Dsui_0662	3.845e-95	321.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,2KVE8@206389|Rhodocyclales	206389|Rhodocyclales	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
PYH1_k127_3066687_5	1144342.PMI40_02830	5.591e-31	123.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,474ZG@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Rubredoxin	rubA	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
PYH1_k127_3066687_2	1120999.JONM01000010_gene4089	9.253e-60	222.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KTJ0@206351|Neisseriales	206351|Neisseriales	KT	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PYH1_k127_3066687_3	640081.Dsui_0659	4.522e-47	181.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,2KWTI@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
PYH1_k127_3066687_4	62928.azo3455	4.709e-38	150.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,2KX20@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemotaxis signal transduction protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
PYH1_k127_3066687_0	640081.Dsui_0657	2.44e-220	705.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,2KU9U@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
PYH1_k127_3066687_6	159087.Daro_3895	7.41e-29	121.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KUBP@206389|Rhodocyclales	206389|Rhodocyclales	KNT	COG0643 Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
PYH1_k127_3067249_3	159087.Daro_2854	8.977e-42	163.0	COG4796@1|root,COG4796@2|Bacteria,1RCNA@1224|Proteobacteria,2WGZA@28216|Betaproteobacteria,2KWAH@206389|Rhodocyclales	206389|Rhodocyclales	U	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
PYH1_k127_3067249_4	1175306.GWL_07800	3.135e-38	148.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,474EK@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	NlpC/P60 family	-	-	-	ko:K13695,ko:K19303	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
PYH1_k127_3067249_2	381666.H16_A0759	1.591e-145	467.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,1JZVS@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	fbpA	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
PYH1_k127_3067249_0	1454004.AW11_01753	9.674e-183	586.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VI20@28216|Betaproteobacteria,1KQ7Q@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
PYH1_k127_3067249_1	62928.azo2207	1.637e-164	524.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,2KVQ7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
PYH1_k127_3067249_5	640081.Dsui_1702	9.174e-15	78.0	COG0810@1|root,COG0810@2|Bacteria,1PTQ3@1224|Proteobacteria,2VWBB@28216|Betaproteobacteria,2KXJV@206389|Rhodocyclales	206389|Rhodocyclales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
PYH1_k127_3068360_6	335543.Sfum_3501	4.824e-37	146.0	COG2271@1|root,COG2271@2|Bacteria,1QXP5@1224|Proteobacteria,43C51@68525|delta/epsilon subdivisions,2X7FD@28221|Deltaproteobacteria,2MR8I@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_3068360_3	1157708.KB907477_gene1060	5.396e-73	252.0	COG2197@1|root,COG2197@2|Bacteria,1R2TM@1224|Proteobacteria,2VJ7V@28216|Betaproteobacteria,4AF37@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH1_k127_3068360_2	1095769.CAHF01000023_gene545	7.358e-101	353.0	COG4585@1|root,COG4585@2|Bacteria,1R1TC@1224|Proteobacteria,2VHUA@28216|Betaproteobacteria,478DI@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3
PYH1_k127_3068360_8	1038867.AXAY01000033_gene2325	1.089e-05	53.0	COG0790@1|root,COG0790@2|Bacteria,1RBMW@1224|Proteobacteria,2U62Z@28211|Alphaproteobacteria,3JY71@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
PYH1_k127_3068360_0	522306.CAP2UW1_2627	2.229e-182	597.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
PYH1_k127_3068360_1	1123393.KB891333_gene2646	1.385e-128	424.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,1KS3P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
PYH1_k127_3068360_5	1163617.SCD_n00847	9.89e-48	176.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
PYH1_k127_3068360_4	580332.Slit_0658	9.822e-49	181.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,44VRM@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
PYH1_k127_3068360_7	381666.H16_A3154	1.865e-33	133.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,1K08C@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
PYH1_k127_3168293_10	1121015.N789_11150	1.42e-18	86.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1X34B@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
PYH1_k127_3168293_6	1304883.KI912532_gene2131	2.979e-90	305.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria,2KV4I@206389|Rhodocyclales	206389|Rhodocyclales	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
PYH1_k127_3168293_1	196367.JNFG01000011_gene6120	2.962e-205	653.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,1K4WQ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
PYH1_k127_3168293_2	760117.JN27_22185	4.017e-191	606.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,473NW@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	phbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH1_k127_3168293_5	1304883.KI912532_gene2134	1.119e-123	400.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2VH8R@28216|Betaproteobacteria,2KVKX@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
PYH1_k127_3168293_7	748247.AZKH_3137	1.156e-68	250.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2VJ2N@28216|Betaproteobacteria,2KVGG@206389|Rhodocyclales	206389|Rhodocyclales	S	synthesis repressor, PhaR	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
PYH1_k127_3168293_0	1163617.SCD_n01841	2.02e-206	659.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
PYH1_k127_3168293_3	1238182.C882_0917	1.633e-160	537.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2JRKW@204441|Rhodospirillales	204441|Rhodospirillales	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH1_k127_3168293_4	1123024.AUII01000002_gene1009	5.305e-152	497.0	COG3135@1|root,COG3135@2|Bacteria,2GNQX@201174|Actinobacteria,4DYUB@85010|Pseudonocardiales	201174|Actinobacteria	Q	Benzoate membrane transport protein	benE	-	-	ko:K05782	-	-	-	-	ko00000,ko02000	2.A.46.1	-	-	BenE
PYH1_k127_3168293_8	587753.EY04_06115	1.133e-60	225.0	COG0697@1|root,COG0697@2|Bacteria,1RDMA@1224|Proteobacteria,1S4HK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_3168293_9	640081.Dsui_2867	1.438e-36	141.0	COG3133@1|root,COG3133@2|Bacteria,1RK6D@1224|Proteobacteria,2VU04@28216|Betaproteobacteria,2KWUY@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
PYH1_k127_3175293_2	1458357.BG58_16195	1.179e-61	216.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,2VQUA@28216|Betaproteobacteria,1K6XY@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	SMART metal-dependent phosphohydrolase, HD region	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
PYH1_k127_3175293_0	243233.MCA2512	1.786e-201	642.0	COG3511@1|root,COG3511@2|Bacteria,1MVNS@1224|Proteobacteria,1RZUB@1236|Gammaproteobacteria,1XDZS@135618|Methylococcales	135618|Methylococcales	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
PYH1_k127_3175293_3	595537.Varpa_1452	6.759e-56	197.0	COG0278@1|root,COG0278@2|Bacteria,1RKVH@1224|Proteobacteria,2WGD8@28216|Betaproteobacteria,4AEKZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
PYH1_k127_3175293_5	713587.THITH_03965	1.87e-20	97.0	COG1416@1|root,COG1416@2|Bacteria,1N64N@1224|Proteobacteria,1SNQX@1236|Gammaproteobacteria,1X1RU@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
PYH1_k127_3175293_4	864073.HFRIS_003888	5.071e-42	158.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2VSE7@28216|Betaproteobacteria,474H2@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Protein chain release factor B	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
PYH1_k127_3175293_1	1121106.JQKB01000013_gene5501	6.269e-115	377.0	COG3181@1|root,COG3181@2|Bacteria,1N7C4@1224|Proteobacteria,2TTPJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	MA20_23135	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_3217518_4	62928.azo1708	2.539e-99	349.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2VJ6W@28216|Betaproteobacteria,2KUEB@206389|Rhodocyclales	206389|Rhodocyclales	T	Periplasmic domain of Sensor histidine kinase RisS	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,RisS_PPD
PYH1_k127_3217518_3	1000565.METUNv1_01175	2.874e-111	367.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI6B@28216|Betaproteobacteria,2KUNC@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	ko:K02483,ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH1_k127_3217518_7	1123269.NX02_08845	1.309e-08	68.0	2EIBB@1|root,33C2R@2|Bacteria,1NH1Q@1224|Proteobacteria,2UJX1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3217518_6	522373.Smlt2944	1.305e-38	161.0	COG2911@1|root,COG2911@2|Bacteria,1NHQB@1224|Proteobacteria,1SVEG@1236|Gammaproteobacteria,1XD9M@135614|Xanthomonadales	135614|Xanthomonadales	S	Porin subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Porin_2
PYH1_k127_3217518_5	1218084.BBJK01000038_gene3572	3.702e-64	229.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2W0Q1@28216|Betaproteobacteria,1K5B3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
PYH1_k127_3217518_0	864051.BurJ1DRAFT_3799	5.883e-189	600.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,2W5VT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
PYH1_k127_3217518_1	1151127.KB906332_gene3640	1.085e-163	539.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RRPI@1236|Gammaproteobacteria,1YN3C@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	CE	Tartrate dehydrogenase	tdh	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
PYH1_k127_3217518_2	257313.BP2291	1.906e-154	497.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VJ9X@28216|Betaproteobacteria,3T1KF@506|Alcaligenaceae	28216|Betaproteobacteria	CE	Tartrate dehydrogenase	ttuC	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
PYH1_k127_3217518_8	323848.Nmul_A2123	4.734e-07	52.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,3732C@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
PYH1_k127_3230435_0	1175306.GWL_24830	1.395e-116	380.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,472BD@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
PYH1_k127_3230435_10	266264.Rmet_1030	4.005e-49	177.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,1K7RJ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Ferredoxin, 2Fe-2S type, ISC system	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
PYH1_k127_3230435_12	640081.Dsui_2377	2.701e-22	111.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,2KXB7@206389|Rhodocyclales	206389|Rhodocyclales	S	FeS assembly protein IscX	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
PYH1_k127_3230435_5	1396141.BATP01000007_gene5722	8.253e-64	225.0	COG0500@1|root,COG2226@2|Bacteria,46V7M@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
PYH1_k127_3230435_15	748280.NH8B_0762	7.208e-06	58.0	28WUG@1|root,2ZITX@2|Bacteria,1P7A0@1224|Proteobacteria,2W6CM@28216|Betaproteobacteria,2KTNV@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3230435_3	314345.SPV1_11301	1.649e-70	244.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria	1224|Proteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
PYH1_k127_3230435_11	309799.DICTH_1609	2.53e-32	134.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	Macro
PYH1_k127_3230435_8	1163617.SCD_n01370	1.796e-56	216.0	28PZA@1|root,2ZCIS@2|Bacteria,1RCMD@1224|Proteobacteria,2VYEF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3230435_2	85643.Tmz1t_2264	1.941e-75	261.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,2KVE7@206389|Rhodocyclales	206389|Rhodocyclales	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
PYH1_k127_3230435_13	1101190.ARWB01000001_gene3080	2.783e-18	100.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2UF6U@28211|Alphaproteobacteria,36YZ7@31993|Methylocystaceae	28211|Alphaproteobacteria	T	BolA-like protein	bolA	GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564	-	ko:K05527,ko:K22066	-	-	-	-	ko00000,ko03000,ko03029	-	-	-	BolA
PYH1_k127_3230435_4	522306.CAP2UW1_3308	2.404e-68	236.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria,1KQ28@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
PYH1_k127_3230435_7	269799.Gmet_0053	3.524e-57	218.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,43TZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PYH1_k127_3230435_9	1397528.Q671_09160	1.083e-54	196.0	COG3791@1|root,COG3791@2|Bacteria,1RD31@1224|Proteobacteria,1S42C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alanine acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GFA
PYH1_k127_3230435_6	1381123.AYOD01000005_gene1210	4.773e-61	214.0	COG2128@1|root,COG2128@2|Bacteria,1RD2I@1224|Proteobacteria,2U7MW@28211|Alphaproteobacteria,43KM1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
PYH1_k127_3230435_1	1095769.CAHF01000005_gene1585	1.143e-112	390.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2VX5D@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
PYH1_k127_3230435_14	1123400.KB904748_gene375	3.719e-13	82.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,1SE9G@1236|Gammaproteobacteria,462Q3@72273|Thiotrichales	72273|Thiotrichales	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
PYH1_k127_3233793_0	420662.Mpe_A3461	4.927e-137	457.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,1KJ9I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
PYH1_k127_3233793_2	228410.NE0014	1.83e-84	297.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,371WE@32003|Nitrosomonadales	28216|Betaproteobacteria	EH	PFAM Glutamine amidotransferase class-I	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
PYH1_k127_3233793_1	1123392.AQWL01000005_gene2964	1.648e-126	410.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,1KS54@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
PYH1_k127_3257981_0	1163617.SCD_n00511	4.036e-240	751.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
PYH1_k127_3257981_3	1454004.AW11_01454	2.457e-25	106.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,1KQ5S@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
PYH1_k127_3257981_1	62928.azo3953	4.803e-68	242.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,2KVFX@206389|Rhodocyclales	206389|Rhodocyclales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
PYH1_k127_3257981_2	1000565.METUNv1_01924	1.098e-41	156.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,2KUSK@206389|Rhodocyclales	206389|Rhodocyclales	S	Stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
PYH1_k127_3285932_8	497321.C664_10947	6.002e-12	65.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,2KUCB@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
PYH1_k127_3285932_5	159087.Daro_3540	6.967e-82	286.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,2KWX6@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH1_k127_3285932_1	748247.AZKH_3095	9.458e-184	581.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KUWF@206389|Rhodocyclales	206389|Rhodocyclales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
PYH1_k127_3285932_0	497321.C664_10957	0.0	1053.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KVAY@206389|Rhodocyclales	206389|Rhodocyclales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
PYH1_k127_3285932_6	269482.Bcep1808_0710	3.796e-39	154.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,1K3P1@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
PYH1_k127_3285932_3	1198452.Jab_2c31690	1.715e-101	354.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,473W2@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
PYH1_k127_3285932_2	640081.Dsui_3074	9.663e-141	454.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,2KUP3@206389|Rhodocyclales	206389|Rhodocyclales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
PYH1_k127_3285932_4	76114.ebA4805	3.897e-92	311.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria,2KV3J@206389|Rhodocyclales	206389|Rhodocyclales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	ppnK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
PYH1_k127_3285932_7	1123367.C666_03265	1.644e-31	138.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,2KUDS@206389|Rhodocyclales	206389|Rhodocyclales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
PYH1_k127_3332436_3	666684.AfiDRAFT_2652	1.98e-19	100.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2TU74@28211|Alphaproteobacteria,3JVQG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_3332436_0	543913.D521_1790	3.067e-95	324.0	COG2021@1|root,COG2021@2|Bacteria,1QU6N@1224|Proteobacteria,2WGNS@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
PYH1_k127_3332436_1	1217720.ALOX01000127_gene1177	1.096e-54	196.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U7NJ@28211|Alphaproteobacteria,2JWT2@204441|Rhodospirillales	204441|Rhodospirillales	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
PYH1_k127_3332436_2	690585.JNNU01000003_gene5519	2.118e-52	192.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,4BNUF@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Molybdopterin-binding domain of aldehyde dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
PYH1_k127_3357302_1	1123023.JIAI01000024_gene4225	6.64e-180	577.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4E1U7@85010|Pseudonocardiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6,2.5.1.66	ko:K01652,ko:K12673	ko00290,ko00331,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00331,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570,M00674	R00006,R00014,R00226,R03050,R04672,R04673,R05465,R08648	RC00027,RC00106,RC00215,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_3357302_3	264198.Reut_B3797	8.598e-119	389.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VI23@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_3357302_0	1207063.P24_13673	2.314e-238	748.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,2JQSB@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
PYH1_k127_3357302_4	670292.JH26_12705	3.973e-93	329.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	MA20_23605	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_3357302_2	1268622.AVS7_00270	8.208e-173	554.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VNJN@28216|Betaproteobacteria,4ACBA@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
PYH1_k127_3361370_5	1163617.SCD_n01889	3.532e-25	109.0	2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,2W4P4@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3361370_3	545264.KB898754_gene1831	1.186e-62	219.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,1S2YE@1236|Gammaproteobacteria,1WY1W@135613|Chromatiales	135613|Chromatiales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
PYH1_k127_3361370_1	292415.Tbd_2269	4.924e-101	338.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45,3.1.1.76	ko:K01061,ko:K22249	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
PYH1_k127_3361370_2	555779.Dthio_PD1623	1.05e-72	261.0	COG1150@1|root,COG1150@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2M85U@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
PYH1_k127_3361370_0	1121430.JMLG01000003_gene654	3.941e-221	706.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,26171@186807|Peptococcaceae	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
PYH1_k127_3361370_4	1121434.AULY01000010_gene2575	6.176e-52	188.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,42NHH@68525|delta/epsilon subdivisions,2WJ6M@28221|Deltaproteobacteria,2M80B@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	qmoA	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,NAD_binding_8,Pyr_redox_2
PYH1_k127_3370594_4	1163617.SCD_n00230	1.426e-22	98.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Mg chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
PYH1_k127_3370594_1	522306.CAP2UW1_4137	5.157e-101	335.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,1KPXN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
PYH1_k127_3370594_2	1123367.C666_13570	3.448e-47	173.0	COG0537@1|root,COG0537@2|Bacteria,1N422@1224|Proteobacteria,2VT5W@28216|Betaproteobacteria,2KWFC@206389|Rhodocyclales	206389|Rhodocyclales	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
PYH1_k127_3370594_0	1163617.SCD_n02776	1.637e-134	436.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM PfkB domain protein	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
PYH1_k127_3370594_3	1454004.AW11_00081	7.821e-36	140.0	2A4J7@1|root,30T5U@2|Bacteria,1RGAU@1224|Proteobacteria,2VU2M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM MJ0042 family finger-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
PYH1_k127_3377298_15	1163617.SCD_n00343	1.621e-96	329.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
PYH1_k127_3377298_20	1163617.SCD_n00342	7.773e-74	271.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	response regulator	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
PYH1_k127_3377298_18	1040982.AXAL01000016_gene5323	5.951e-83	293.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,2U5HN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PYH1_k127_3377298_7	1163617.SCD_n02706	1.985e-175	572.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
PYH1_k127_3377298_10	713586.KB900536_gene1022	6.368e-134	439.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1RS7Z@1236|Gammaproteobacteria,1WX2A@135613|Chromatiales	135613|Chromatiales	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
PYH1_k127_3377298_13	864051.BurJ1DRAFT_3325	4.88e-106	357.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
PYH1_k127_3377298_33	292415.Tbd_2476	1.039e-26	116.0	2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3377298_2	580332.Slit_1678	1.751e-315	978.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,44V9S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
PYH1_k127_3377298_3	864051.BurJ1DRAFT_3329	4.262e-251	784.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria,1KN5P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Fe-S oxidoreductase	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
PYH1_k127_3377298_14	1163617.SCD_n02712	7.712e-105	350.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
PYH1_k127_3377298_22	1266914.ATUK01000012_gene210	5.565e-57	199.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1WYFA@135613|Chromatiales	135613|Chromatiales	P	part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
PYH1_k127_3377298_29	292415.Tbd_2481	1.948e-33	138.0	COG2168@1|root,COG2168@2|Bacteria,1PTT8@1224|Proteobacteria,2VWF4@28216|Betaproteobacteria,1KT55@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
PYH1_k127_3377298_23	1163617.SCD_n02715	8.196e-52	190.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,2VSQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfur relay protein TusC DsrF	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
PYH1_k127_3377298_21	1163617.SCD_n02716	6.119e-61	211.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,2VR8N@28216|Betaproteobacteria	28216|Betaproteobacteria	P	sulfur relay protein TusD DsrE	-	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
PYH1_k127_3377298_6	1123393.KB891316_gene1850	5.565e-204	672.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria,1KSR2@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
PYH1_k127_3377298_4	292415.Tbd_1369	1.775e-218	688.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	sulfite reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
PYH1_k127_3377298_36	864051.BurJ1DRAFT_3337	8.601e-19	92.0	2EMP6@1|root,33FBM@2|Bacteria,1NGBE@1224|Proteobacteria,2VYCB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3377298_31	864051.BurJ1DRAFT_3338	4.623e-30	130.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,2VVIY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cas6 Crispr	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
PYH1_k127_3377298_26	1163617.SCD_n02721	7.896e-39	159.0	COG2920@1|root,COG2920@2|Bacteria,1N2HP@1224|Proteobacteria,2VVGF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
PYH1_k127_3377298_25	580332.Slit_1690	1.975e-47	177.0	COG0425@1|root,COG0425@2|Bacteria,1PX23@1224|Proteobacteria,2WCJT@28216|Betaproteobacteria,44W8S@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
PYH1_k127_3377298_24	1163617.SCD_n02723	9.887e-51	193.0	28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,2VUGA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3377298_28	396588.Tgr7_2280	4.127e-34	144.0	COG2920@1|root,COG2920@2|Bacteria,1N6BU@1224|Proteobacteria,1S6FJ@1236|Gammaproteobacteria,1WYPC@135613|Chromatiales	135613|Chromatiales	P	part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
PYH1_k127_3377298_17	580332.Slit_1692	5.398e-87	295.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria,44W7U@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
PYH1_k127_3377298_32	1123393.KB891333_gene2506	6.934e-27	110.0	2ESIQ@1|root,33K3E@2|Bacteria,1NJ20@1224|Proteobacteria,2WCCZ@28216|Betaproteobacteria,1KTFU@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3377298_34	1163617.SCD_n01889	3.465e-26	123.0	2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,2W4P4@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3377298_16	1469245.JFBG01000001_gene487	3.819e-90	317.0	COG0727@1|root,COG0727@2|Bacteria,1R3YG@1224|Proteobacteria,1RQT5@1236|Gammaproteobacteria,1X0G7@135613|Chromatiales	135613|Chromatiales	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
PYH1_k127_3377298_12	1038867.AXAY01000015_gene6941	7.544e-107	355.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2TUWC@28211|Alphaproteobacteria,3K2R0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	hpcG	-	-	ko:K02509	ko00350,ko01120,map00350,map01120	-	R04132,R06897	RC01615,RC02595	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
PYH1_k127_3377298_37	1366050.N234_08145	1.344e-10	63.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1JZMS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	dmpC	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH1_k127_3377298_1	1458357.BG58_05605	0.0	1034.0	COG3243@1|root,COG3243@2|Bacteria,1MUNE@1224|Proteobacteria,2VJZW@28216|Betaproteobacteria,1K3Z3@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Protein of unknown function (DUF3141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3141
PYH1_k127_3377298_9	264198.Reut_A1202	1.245e-142	458.0	COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,2VJ4B@28216|Betaproteobacteria,1K2V8@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
PYH1_k127_3377298_8	388051.AUFE01000001_gene1907	1.067e-168	537.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,1K1WI@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
PYH1_k127_3377298_11	1458357.BG58_05620	1.938e-130	436.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VJQ0@28216|Betaproteobacteria,1JZNA@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI_1	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH1_k127_3377298_27	522306.CAP2UW1_2910	1.919e-35	152.0	COG5380@1|root,COG5380@2|Bacteria,1N6UY@1224|Proteobacteria,2VRU4@28216|Betaproteobacteria	28216|Betaproteobacteria	O	lipid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3377298_38	640081.Dsui_2292	0.0002229	48.0	COG0724@1|root,COG0724@2|Bacteria,1NJB7@1224|Proteobacteria,2VY6N@28216|Betaproteobacteria,2KXJF@206389|Rhodocyclales	206389|Rhodocyclales	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
PYH1_k127_3377298_30	929556.Solca_2855	8.676e-31	141.0	COG2930@1|root,COG2930@2|Bacteria,4NP71@976|Bacteroidetes	976|Bacteroidetes	S	Pfam Family of	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
PYH1_k127_3377298_0	1469245.JFBG01000001_gene489	0.0	1104.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales	135613|Chromatiales	C	reductase, alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
PYH1_k127_3377298_19	1123393.KB891317_gene2372	2.731e-79	267.0	COG1146@1|root,COG1146@2|Bacteria,1RC9N@1224|Proteobacteria,2W1W6@28216|Betaproteobacteria,1KSRH@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_9
PYH1_k127_3377298_5	396588.Tgr7_0353	1.347e-212	665.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales	135613|Chromatiales	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
PYH1_k127_3377298_35	1121035.AUCH01000007_gene575	2.679e-25	109.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,2KUIC@206389|Rhodocyclales	206389|Rhodocyclales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
PYH1_k127_3395037_3	690585.JNNU01000006_gene1193	2.265e-11	64.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,4B8SA@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	L-lactate dehydrogenase	-	-	1.1.2.3,1.1.99.31	ko:K00101,ko:K15054	ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120	-	R00196,R04160,R07664	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
PYH1_k127_3395037_0	365046.Rta_17950	2.54e-145	473.0	COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2VISJ@28216|Betaproteobacteria,4ABYT@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD binding domain	-	-	1.14.13.1,1.14.13.24	ko:K00480,ko:K22270	ko00362,ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00362,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R02589,R05632,R06915,R06936,R06939	RC00046,RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
PYH1_k127_3395037_1	1380355.JNIJ01000054_gene1839	2.053e-143	463.0	COG3391@1|root,COG3391@2|Bacteria,1MXRF@1224|Proteobacteria,2U1E9@28211|Alphaproteobacteria,3JTTY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
PYH1_k127_3395037_2	1121861.KB899944_gene3892	3.549e-52	190.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
PYH1_k127_3404079_0	1123393.KB891327_gene349	2.443e-121	398.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KSSQ@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Cation transporting ATPase, C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,E1-E2_ATPase,Hydrolase
PYH1_k127_3404079_1	1121035.AUCH01000001_gene2081	7.435e-95	324.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,2KUDT@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	fnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH1_k127_3404079_3	196367.JNFG01000016_gene3999	1.682e-13	75.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VVNY@28216|Betaproteobacteria,1K970@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PYH1_k127_3404079_2	760117.JN27_14495	1.335e-68	239.0	COG2197@1|root,COG2197@2|Bacteria,1RENN@1224|Proteobacteria,2VR4J@28216|Betaproteobacteria,473UU@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH1_k127_3433942_0	864051.BurJ1DRAFT_0984	4.858e-235	735.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,1KKFD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	polyphosphate kinase	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
PYH1_k127_3456145_0	1038867.AXAY01000039_gene4523	8.666e-226	708.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JX4Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
PYH1_k127_3456145_1	1095769.CAHF01000021_gene911	7.26e-24	110.0	29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2VT23@28216|Betaproteobacteria,474HM@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	tctB4	-	-	-	-	-	-	-	-	-	-	-	TctB
PYH1_k127_3466257_0	1122135.KB893157_gene205	4.333e-152	489.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_3466257_2	1279038.KB907337_gene78	5.343e-21	105.0	COG3090@1|root,COG3090@2|Bacteria,1NCZ4@1224|Proteobacteria,2UFTA@28211|Alphaproteobacteria,2JUUZ@204441|Rhodospirillales	204441|Rhodospirillales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_3466257_1	1123355.JHYO01000009_gene3089	3.229e-101	338.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TQVT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_3474846_7	1125863.JAFN01000001_gene3100	2.671e-16	78.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_3474846_0	1187851.A33M_2769	4.214e-295	915.0	COG4799@1|root,COG4799@2|Bacteria,1Q9BU@1224|Proteobacteria	1224|Proteobacteria	I	PFAM carboxyl transferase	gcdA	-	4.1.1.70	ko:K01615	ko00362,ko00650,ko01120,map00362,map00650,map01120	-	R03028	RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.3	-	-	Carboxyl_trans
PYH1_k127_3474846_5	1121920.AUAU01000005_gene933	2.16e-38	151.0	2EKGK@1|root,33E6M@2|Bacteria	2|Bacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH1_k127_3474846_4	1095769.CAHF01000022_gene83	4.63e-48	177.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2VH95@28216|Betaproteobacteria,472S2@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	gstA	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_3
PYH1_k127_3474846_6	1267533.KB906741_gene653	5.829e-30	121.0	COG4274@1|root,COG4274@2|Bacteria,3Y87J@57723|Acidobacteria	57723|Acidobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
PYH1_k127_3474846_1	864051.BurJ1DRAFT_2300	1.135e-169	540.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2VI5X@28216|Betaproteobacteria,1KMVB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
PYH1_k127_3474846_2	1245469.S58_64010	4.461e-169	544.0	COG0683@1|root,COG0683@2|Bacteria,1N45V@1224|Proteobacteria,2U18M@28211|Alphaproteobacteria,3JVGS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH1_k127_3474846_3	1173263.Syn7502_00322	8.454e-88	305.0	COG0671@1|root,COG0671@2|Bacteria,1GHH3@1117|Cyanobacteria,1H44C@1129|Synechococcus	1117|Cyanobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PAP2
PYH1_k127_3474846_8	665942.HMPREF1022_02003	1.258e-14	78.0	COG0730@1|root,COG0730@2|Bacteria,1NAFA@1224|Proteobacteria,42Y8A@68525|delta/epsilon subdivisions,2WU4U@28221|Deltaproteobacteria,2MBAN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
PYH1_k127_3494480_0	85643.Tmz1t_1738	3.527e-185	601.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,2KUMC@206389|Rhodocyclales	206389|Rhodocyclales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PYH1_k127_3494480_1	1454004.AW11_00834	5.293e-98	326.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,1KPWR@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
PYH1_k127_3495185_5	525897.Dbac_1340	7.559e-13	69.0	2DEPN@1|root,2ZNRE@2|Bacteria,1Q16E@1224|Proteobacteria,436HH@68525|delta/epsilon subdivisions,2X13V@28221|Deltaproteobacteria,2ME5Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
PYH1_k127_3495185_1	1254432.SCE1572_16385	2.508e-102	357.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
PYH1_k127_3495185_4	1123393.KB891317_gene2266	8.895e-75	261.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,1KSTM@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp33 protein	-	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
PYH1_k127_3495185_2	1187851.A33M_0281	7.723e-95	324.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3FD1Y@34008|Rhodovulum	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_3495185_3	1121033.AUCF01000030_gene166	4.53e-89	314.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,2JS5W@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_3495185_0	1121033.AUCF01000030_gene167	5.329e-115	379.0	COG4177@1|root,COG4177@2|Bacteria,1NE3E@1224|Proteobacteria,2TTWY@28211|Alphaproteobacteria,2JT5A@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH1_k127_3504106_3	870187.Thini_2353	6.109e-29	124.0	2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,1SH3A@1236|Gammaproteobacteria,463C1@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3504106_0	76114.ebB144	5.306e-65	225.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,2VR6S@28216|Betaproteobacteria,2KW34@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	2.7.7.70	ko:K21345	ko00540,ko01100,map00540,map01100	M00064	R05644	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
PYH1_k127_3504106_2	76114.ebA1464	6.076e-59	218.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,2KWEB@206389|Rhodocyclales	206389|Rhodocyclales	S	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
PYH1_k127_3504106_1	748247.AZKH_3740	8.957e-64	221.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,2KVWJ@206389|Rhodocyclales	206389|Rhodocyclales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
PYH1_k127_3536722_7	258594.RPA3755	1.476e-08	57.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,3JVT1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	MA20_16210	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
PYH1_k127_3536722_6	1120956.JHZK01000002_gene1028	3.879e-54	203.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2TV0H@28211|Alphaproteobacteria,1JPGW@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	MA20_04270	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH1_k127_3536722_4	977880.RALTA_A0568	8.188e-80	277.0	COG3181@1|root,COG3181@2|Bacteria,1NTHU@1224|Proteobacteria,2VZE0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_3536722_1	1502851.FG93_00182	1.692e-169	562.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
PYH1_k127_3536722_2	266264.Rmet_1791	4.411e-143	467.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,2VIYG@28216|Betaproteobacteria,1K520@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
PYH1_k127_3536722_3	266264.Rmet_1792	5.041e-107	351.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VIKP@28216|Betaproteobacteria,1K47S@119060|Burkholderiaceae	28216|Betaproteobacteria	V	abc transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH1_k127_3536722_0	264198.Reut_B5858	6.203e-172	558.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,2VNEP@28216|Betaproteobacteria,1K3V4@119060|Burkholderiaceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH1_k127_3536722_5	391038.Bphy_3709	2.643e-70	243.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,2VMYG@28216|Betaproteobacteria,1K3ES@119060|Burkholderiaceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH1_k127_3552654_0	1411123.JQNH01000001_gene266	2.946e-314	1007.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
PYH1_k127_3552654_2	604331.AUHY01000006_gene831	1.798e-238	747.0	COG0365@1|root,COG0365@2|Bacteria,1WNGH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_3552654_1	1380394.JADL01000003_gene4767	6.29e-264	823.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JUXN@204441|Rhodospirillales	204441|Rhodospirillales	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PYH1_k127_3552654_6	935840.JAEQ01000003_gene278	2.141e-49	187.0	COG0685@1|root,COG0685@2|Bacteria,1MVWT@1224|Proteobacteria,2TTSF@28211|Alphaproteobacteria,43KAG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	COG0685 5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
PYH1_k127_3552654_5	1380394.JADL01000023_gene64	5.029e-107	359.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria,2JW4C@204441|Rhodospirillales	204441|Rhodospirillales	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
PYH1_k127_3552654_3	1244869.H261_04842	7.108e-220	702.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2TRV7@28211|Alphaproteobacteria,2JPYI@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme	-	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
PYH1_k127_3552654_4	296591.Bpro_1464	1.001e-107	365.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,2VJKU@28216|Betaproteobacteria,4AB6Q@80864|Comamonadaceae	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
PYH1_k127_3552654_7	762376.AXYL_03039	1.411e-28	119.0	COG0583@1|root,COG0583@2|Bacteria,1R80K@1224|Proteobacteria,2WGDV@28216|Betaproteobacteria,3T8XA@506|Alcaligenaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH1_k127_3553796_2	1218084.BBJK01000075_gene5239	3.476e-62	227.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,2VXDK@28216|Betaproteobacteria,1K5E1@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
PYH1_k127_3553796_4	1157708.KB907466_gene659	1.17e-24	109.0	2CH9M@1|root,332CJ@2|Bacteria,1N7TS@1224|Proteobacteria,2VX3H@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3553796_3	1121374.KB891576_gene580	2.322e-47	180.0	COG0454@1|root,COG0456@2|Bacteria,1RJ1K@1224|Proteobacteria,1S6RV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PYH1_k127_3553796_1	358220.C380_06625	8.712e-165	533.0	COG1075@1|root,COG1075@2|Bacteria,1MWM9@1224|Proteobacteria,2VN20@28216|Betaproteobacteria,4ACT5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Lipase (class 2)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
PYH1_k127_3553796_5	396588.Tgr7_3155	2.829e-06	53.0	COG2013@1|root,COG2013@2|Bacteria	2|Bacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
PYH1_k127_3553796_0	1173027.Mic7113_4587	5.175e-174	559.0	COG0405@1|root,COG0405@2|Bacteria,1G14N@1117|Cyanobacteria,1H83V@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
PYH1_k127_3573276_0	1304877.KI519399_gene4063	4.67e-129	428.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,3JT0K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	MA20_16505	-	1.1.1.350	ko:K00073,ko:K13574	ko00230,ko01120,map00230,map01120	-	R02935,R02936	RC00169	ko00000,ko00001,ko01000	-	-	-	Ldh_2
PYH1_k127_3573276_1	395494.Galf_1105	1.057e-72	259.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,44WHA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
PYH1_k127_3573276_2	1126627.BAWE01000005_gene6327	1.131e-11	66.0	COG3181@1|root,COG3181@2|Bacteria,1NP0J@1224|Proteobacteria,2U41R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_3598218_4	85643.Tmz1t_3406	1.204e-49	179.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,2KVHN@206389|Rhodocyclales	206389|Rhodocyclales	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
PYH1_k127_3598218_1	395494.Galf_2294	5.069e-174	558.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,44VPG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
PYH1_k127_3598218_5	1031711.RSPO_c00789	5.745e-33	138.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,1K7SV@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
PYH1_k127_3598218_0	1304883.KI912532_gene3229	3.266e-285	887.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,2KV11@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
PYH1_k127_3598218_3	640081.Dsui_3326	8.371e-133	429.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,2KVVV@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
PYH1_k127_3598218_2	1095769.CAHF01000009_gene1380	1.127e-154	507.0	COG4122@1|root,COG4122@2|Bacteria,1QWCT@1224|Proteobacteria,2VJBK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3608398_0	1095769.CAHF01000006_gene1959	0.0	1177.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,47292@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
PYH1_k127_3608398_1	667632.KB890164_gene2064	5.935e-59	208.0	COG2816@1|root,COG2816@2|Bacteria,1REUJ@1224|Proteobacteria,2VRF4@28216|Betaproteobacteria,1K23S@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,Nudix_N_2
PYH1_k127_364729_13	323848.Nmul_A0510	3.884e-116	387.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VZIT@28216|Betaproteobacteria,371QJ@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
PYH1_k127_364729_35	1120949.KB903311_gene780	7.381e-29	120.0	COG3152@1|root,COG3152@2|Bacteria,2IQHK@201174|Actinobacteria,4DFBW@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
PYH1_k127_364729_29	62928.azo0662	2.585e-46	174.0	COG5455@1|root,COG5455@2|Bacteria,1RJ9A@1224|Proteobacteria,2VRVC@28216|Betaproteobacteria,2KWPU@206389|Rhodocyclales	206389|Rhodocyclales	S	response to cobalt ion	-	-	-	-	-	-	-	-	-	-	-	-	RcnB
PYH1_k127_364729_1	1000565.METUNv1_01141	1.926e-287	894.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,2KUTN@206389|Rhodocyclales	206389|Rhodocyclales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
PYH1_k127_364729_7	1157708.KB907462_gene897	8.889e-157	501.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,4AB2U@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
PYH1_k127_364729_28	1437824.BN940_07046	6.227e-48	180.0	COG1309@1|root,COG1309@2|Bacteria,1RADD@1224|Proteobacteria,2VW81@28216|Betaproteobacteria,3T4Y6@506|Alcaligenaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PYH1_k127_364729_4	1157708.KB907462_gene897	5.208e-193	609.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,4AB2U@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
PYH1_k127_364729_36	204773.HEAR2448	8.063e-29	117.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,474TX@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	'Cold-shock' DNA-binding domain	cspD2	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
PYH1_k127_364729_38	745411.B3C1_13044	3.212e-26	109.0	2C3Q0@1|root,334WS@2|Bacteria,1NBS8@1224|Proteobacteria,1SE5H@1236|Gammaproteobacteria,1JB4Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	IV02_14570	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_364729_40	1442599.JAAN01000005_gene995	9.938e-10	63.0	COG2261@1|root,COG2261@2|Bacteria,1N8B3@1224|Proteobacteria,1T0FC@1236|Gammaproteobacteria,1XD0D@135614|Xanthomonadales	135614|Xanthomonadales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
PYH1_k127_364729_0	1288494.EBAPG3_12210	0.0	1352.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,3743H@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
PYH1_k127_364729_8	762376.AXYL_06091	2.183e-156	508.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VMYW@28216|Betaproteobacteria,3T3PZ@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH1_k127_364729_30	1354722.JQLS01000004_gene4232	5.915e-44	170.0	COG2185@1|root,COG2185@2|Bacteria,1QU3N@1224|Proteobacteria,2TVY1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
PYH1_k127_364729_2	762376.AXYL_06089	6.602e-243	780.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Methylmalonyl-CoA mutase	icmF	-	5.4.99.2,5.4.99.63,5.4.99.64	ko:K01848,ko:K14447,ko:K20906	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833,R09292	RC00395,RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
PYH1_k127_364729_21	1354722.JQLS01000004_gene4234	3.013e-61	220.0	COG1024@1|root,COG1024@2|Bacteria,1MXEN@1224|Proteobacteria,2TTIH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_364729_22	1207063.P24_07779	3.165e-60	217.0	COG1414@1|root,COG1414@2|Bacteria,1MYP0@1224|Proteobacteria,2VFJK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
PYH1_k127_364729_41	264198.Reut_A2659	3.611e-08	59.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,1K51A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3,SLT
PYH1_k127_364729_31	1071679.BG57_32300	4.671e-40	151.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,1K51A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3,SLT
PYH1_k127_364729_11	1217718.ALOU01000038_gene3330	1.464e-119	391.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,1K51A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3,SLT
PYH1_k127_364729_33	366602.Caul_0177	2.671e-34	142.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2UBYB@28211|Alphaproteobacteria,2KHAG@204458|Caulobacterales	204458|Caulobacterales	T	TspO MBR family protein	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
PYH1_k127_364729_10	543913.D521_0390	7.346e-122	403.0	COG0589@1|root,COG0861@1|root,COG0589@2|Bacteria,COG0861@2|Bacteria,1MXSK@1224|Proteobacteria,2VHZ5@28216|Betaproteobacteria,1KQ0Z@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
PYH1_k127_364729_24	323848.Nmul_A2215	4.623e-59	215.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,371MU@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
PYH1_k127_364729_18	1304883.KI912532_gene2740	1.163e-78	284.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,2KUXU@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
PYH1_k127_364729_25	1458427.BAWN01000022_gene1445	6.867e-54	194.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,4ADQH@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
PYH1_k127_364729_12	1266909.AUAG01000001_gene1567	1.261e-118	398.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,1WVW3@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
PYH1_k127_364729_15	62928.azo1481	1.26e-102	343.0	COG3329@1|root,COG3329@2|Bacteria,1N85P@1224|Proteobacteria,2VI5D@28216|Betaproteobacteria,2KVD4@206389|Rhodocyclales	206389|Rhodocyclales	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
PYH1_k127_364729_39	494419.ALPM01000100_gene1046	1.986e-15	89.0	COG0347@1|root,COG0347@2|Bacteria,2H6FT@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_364729_42	1127673.GLIP_2679	0.0001777	46.0	2DT0U@1|root,33I6V@2|Bacteria,1NMHR@1224|Proteobacteria,1SGK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_364729_9	1304883.KI912532_gene984	7.061e-146	471.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,2KVG7@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
PYH1_k127_364729_23	640081.Dsui_0477	4.311e-60	217.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,2KW31@206389|Rhodocyclales	206389|Rhodocyclales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_6,TolA_bind_tri
PYH1_k127_364729_27	522306.CAP2UW1_4224	5.472e-48	193.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,1KQ3V@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
PYH1_k127_364729_5	640081.Dsui_0479	1.972e-179	571.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,2KUUQ@206389|Rhodocyclales	206389|Rhodocyclales	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
PYH1_k127_364729_26	1304883.KI912532_gene976	3.448e-48	187.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,2VKUS@28216|Betaproteobacteria,2KVZ9@206389|Rhodocyclales	206389|Rhodocyclales	M	TonB C terminal	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
PYH1_k127_364729_37	1266925.JHVX01000011_gene1493	3.577e-28	128.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria,3737B@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
PYH1_k127_364729_16	266265.Bxe_A3917	1.628e-100	334.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,1K1BT@119060|Burkholderiaceae	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
PYH1_k127_364729_34	1123256.KB907932_gene2934	1.582e-30	137.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1X6W5@135614|Xanthomonadales	135614|Xanthomonadales	S	Acyl-CoA thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
PYH1_k127_364729_6	582744.Msip34_2404	2.48e-170	541.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,2KKIG@206350|Nitrosomonadales	206350|Nitrosomonadales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
PYH1_k127_364729_19	1500894.JQNN01000001_gene4313	2.836e-71	255.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,473AX@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
PYH1_k127_364729_20	580332.Slit_0512	1.175e-67	246.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,44VRQ@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
PYH1_k127_364729_14	1266925.JHVX01000011_gene1499	5.87e-116	377.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,371YE@32003|Nitrosomonadales	28216|Betaproteobacteria	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
PYH1_k127_364729_3	543728.Vapar_2668	5.581e-227	712.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,4AA9X@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
PYH1_k127_364729_17	1380394.JADL01000001_gene2257	5.071e-79	273.0	COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,2U4JI@28211|Alphaproteobacteria,2JUE6@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_364729_32	1207063.P24_13548	3.861e-38	144.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,2JQV0@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
PYH1_k127_3669739_2	1123487.KB892835_gene3435	2.054e-72	265.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,2KUCJ@206389|Rhodocyclales	206389|Rhodocyclales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
PYH1_k127_3669739_4	1123392.AQWL01000004_gene2847	6.233e-50	180.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria,1KT44@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
PYH1_k127_3669739_6	1163408.UU9_13468	1.902e-28	119.0	COG3063@1|root,COG3063@2|Bacteria,1QV1V@1224|Proteobacteria,1T6RC@1236|Gammaproteobacteria,1X7ZA@135614|Xanthomonadales	135614|Xanthomonadales	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
PYH1_k127_3669739_0	1095769.CAHF01000013_gene3231	1.516e-278	879.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria	1224|Proteobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
PYH1_k127_3669739_3	1255043.TVNIR_3271	1.616e-53	190.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S9TF@1236|Gammaproteobacteria,1X140@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
PYH1_k127_3669739_5	1122604.JONR01000003_gene1358	4.171e-42	164.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,1RQEK@1236|Gammaproteobacteria,1XCMR@135614|Xanthomonadales	135614|Xanthomonadales	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
PYH1_k127_3669739_1	1123368.AUIS01000014_gene2307	2.882e-88	302.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,2NDXJ@225057|Acidithiobacillales	225057|Acidithiobacillales	M	type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K11003	ko03070,ko05133,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	8.A.1.3.1,8.A.1.3.2	-	-	Biotin_lipoyl_2,HlyD_3
PYH1_k127_3688048_2	1266925.JHVX01000005_gene1882	4.447e-42	158.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,3720Z@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
PYH1_k127_3688048_3	667632.KB890185_gene478	5.875e-21	96.0	COG3360@1|root,COG3360@2|Bacteria,1PW6C@1224|Proteobacteria,2VXDE@28216|Betaproteobacteria,1KB0W@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
PYH1_k127_3688048_1	305700.B447_15151	1.105e-106	352.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2VH81@28216|Betaproteobacteria,2KVGE@206389|Rhodocyclales	206389|Rhodocyclales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_3688048_0	1380394.JADL01000002_gene1603	3.819e-134	435.0	COG1024@1|root,COG1024@2|Bacteria,1NTWU@1224|Proteobacteria,2UPY0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_3689863_1	1000565.METUNv1_00703	4.809e-50	184.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
PYH1_k127_3689863_0	1163617.SCD_n00808	0.0	1219.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
PYH1_k127_371903_2	748247.AZKH_0631	6.831e-130	437.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,2KU9I@206389|Rhodocyclales	206389|Rhodocyclales	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
PYH1_k127_371903_0	640081.Dsui_0130	0.0	1056.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KVTV@206389|Rhodocyclales	206389|Rhodocyclales	C	Malic enzyme	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
PYH1_k127_371903_3	1000565.METUNv1_00266	1.917e-129	425.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,2KUYE@206389|Rhodocyclales	206389|Rhodocyclales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
PYH1_k127_371903_8	497321.C664_09020	3.166e-20	92.0	2EDY7@1|root,337T3@2|Bacteria,1RKSZ@1224|Proteobacteria,2VTSJ@28216|Betaproteobacteria,2KWV4@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_371903_1	404589.Anae109_2985	1.745e-135	461.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2YWUY@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
PYH1_k127_371903_4	1207063.P24_02906	2.843e-116	400.0	COG1638@1|root,COG1638@2|Bacteria,1MWAM@1224|Proteobacteria,2TTQ8@28211|Alphaproteobacteria,2JRAH@204441|Rhodospirillales	204441|Rhodospirillales	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_371903_9	296591.Bpro_3403	1.313e-16	81.0	2END2@1|root,33G0J@2|Bacteria,1NIFI@1224|Proteobacteria,2VVU7@28216|Betaproteobacteria,4AIVD@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_371903_5	522306.CAP2UW1_2142	1.315e-65	233.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2VREV@28216|Betaproteobacteria,1KQQ5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PYH1_k127_371903_7	1122604.JONR01000003_gene1358	5.398e-41	160.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,1RQEK@1236|Gammaproteobacteria,1XCMR@135614|Xanthomonadales	135614|Xanthomonadales	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
PYH1_k127_371903_6	640081.Dsui_3240	5.452e-50	183.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,2KUFS@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	-	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
PYH1_k127_372251_1	637389.Acaty_c2281	2.876e-179	577.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,2NE68@225057|Acidithiobacillales	225057|Acidithiobacillales	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
PYH1_k127_372251_0	887062.HGR_13999	1.025e-227	727.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria,4A9RB@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD	-	1.1.2.4,1.1.3.15,1.1.5.12	ko:K00102,ko:K00104,ko:K03777	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475,R00704,R11591	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
PYH1_k127_372251_2	1502852.FG94_02032	4.442e-31	134.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,4725H@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
PYH1_k127_376309_4	316055.RPE_1702	5.607e-37	141.0	COG1028@1|root,COG1028@2|Bacteria,1MWGK@1224|Proteobacteria,2TVQ8@28211|Alphaproteobacteria,3JQVW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	MA20_16385	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
PYH1_k127_376309_5	296591.Bpro_4464	1.149e-24	113.0	COG0745@1|root,COG0745@2|Bacteria,1R7VB@1224|Proteobacteria,2VI0D@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg
PYH1_k127_376309_1	1349767.GJA_1527	1.72e-165	535.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,472YU@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
PYH1_k127_376309_0	795666.MW7_0380	5.852e-186	592.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,1K1SF@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
PYH1_k127_376309_3	580332.Slit_2295	6.118e-64	228.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,44VNR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
PYH1_k127_376309_2	292415.Tbd_0970	6.192e-129	420.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,1KS9R@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
PYH1_k127_3767986_2	1000565.METUNv1_03304	1.089e-14	74.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,2KW2I@206389|Rhodocyclales	206389|Rhodocyclales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
PYH1_k127_3767986_0	62928.azo3449	2.701e-192	610.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,2KUUJ@206389|Rhodocyclales	206389|Rhodocyclales	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PYH1_k127_3767986_1	640081.Dsui_0441	1.436e-186	593.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria,2KUHE@206389|Rhodocyclales	206389|Rhodocyclales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
PYH1_k127_3780487_0	795666.MW7_3103	4.082e-190	602.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,1K0U8@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PYH1_k127_3780487_1	1304883.KI912532_gene1572	2.039e-72	249.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,2KVGS@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
PYH1_k127_3796309_6	316055.RPE_3064	0.0001945	46.0	2E0AX@1|root,32VY8@2|Bacteria,1N21Q@1224|Proteobacteria,2UECC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
PYH1_k127_3796309_4	1244869.H261_21688	2.896e-63	232.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PYH1_k127_3796309_2	76114.ebA723	1.965e-103	342.0	COG1028@1|root,COG1028@2|Bacteria,1RCD5@1224|Proteobacteria,2W04R@28216|Betaproteobacteria,2KXRA@206389|Rhodocyclales	206389|Rhodocyclales	IQ	KR domain	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
PYH1_k127_3796309_0	76114.ebA722	1.168e-146	467.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2VHSP@28216|Betaproteobacteria,2KYCR@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_3796309_1	1380394.JADL01000017_gene522	6.373e-143	476.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria,2JPUP@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_3796309_3	76114.ebA715	1.193e-73	269.0	COG1309@1|root,COG1309@2|Bacteria,1R4VA@1224|Proteobacteria,2VT2X@28216|Betaproteobacteria,2KYUM@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PYH1_k127_3796309_5	76114.ebA720	1.657e-35	149.0	COG1024@1|root,COG1024@2|Bacteria,1REB8@1224|Proteobacteria,2W1XT@28216|Betaproteobacteria,2KYP7@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_3798607_3	1380394.JADL01000011_gene3800	2.45e-19	91.0	2DMUX@1|root,32TU3@2|Bacteria,1RB0V@1224|Proteobacteria,2U5CJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
PYH1_k127_3798607_0	265072.Mfla_1247	0.0	1366.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,2KKIM@206350|Nitrosomonadales	206350|Nitrosomonadales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
PYH1_k127_3798607_2	1121033.AUCF01000001_gene2030	3.591e-79	274.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2JRZ1@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_3798607_1	1265502.KB905934_gene3226	2.696e-150	485.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,4AA2M@80864|Comamonadaceae	28216|Betaproteobacteria	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
PYH1_k127_3798607_4	582744.Msip34_0219	1.68e-12	78.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,2KKKA@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM DnaA regulatory inactivator Hda	-	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
PYH1_k127_3860519_0	228410.NE2158	1.915e-167	533.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,372F1@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH1_k127_3860519_1	1265502.KB905929_gene2233	5.164e-41	171.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,4AE0B@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
PYH1_k127_3860519_2	1100721.ALKO01000003_gene2178	5.313e-28	121.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,4ADH1@80864|Comamonadaceae	28216|Betaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
PYH1_k127_3862897_10	1288494.EBAPG3_21990	4.935e-51	183.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1PV5D@1224|Proteobacteria,2WB3J@28216|Betaproteobacteria,37281@32003|Nitrosomonadales	28216|Betaproteobacteria	CEH	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
PYH1_k127_3862897_7	1205680.CAKO01000040_gene1064	1.112e-88	306.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TSYF@28211|Alphaproteobacteria,2JS8E@204441|Rhodospirillales	204441|Rhodospirillales	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
PYH1_k127_3862897_0	1205680.CAKO01000040_gene1065	0.0	1192.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,2JPGD@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
PYH1_k127_3862897_3	1205680.CAKO01000040_gene1066	5.033e-233	728.0	COG2816@1|root,COG2816@2|Bacteria,1MV1F@1224|Proteobacteria,2TTRT@28211|Alphaproteobacteria,2JQZX@204441|Rhodospirillales	204441|Rhodospirillales	L	COG1180 Pyruvate-formate lyase-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3862897_9	1205680.CAKO01000040_gene1067	3.794e-82	287.0	COG2122@1|root,COG2122@2|Bacteria,1MV9Z@1224|Proteobacteria,2TTG1@28211|Alphaproteobacteria,2JRRD@204441|Rhodospirillales	204441|Rhodospirillales	S	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3862897_5	887062.HGR_10075	1.686e-105	347.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2VIMK@28216|Betaproteobacteria,4ADA4@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
PYH1_k127_3862897_4	1205680.CAKO01000040_gene1070	2.818e-178	571.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2TTAH@28211|Alphaproteobacteria,2JQHT@204441|Rhodospirillales	204441|Rhodospirillales	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_3862897_2	358220.C380_01170	4.491e-251	790.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,1MY1E@1224|Proteobacteria,2VMZ5@28216|Betaproteobacteria,4AB9X@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_3862897_6	1121106.JQKB01000022_gene3707	9.005e-99	354.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TR6T@28211|Alphaproteobacteria,2JQUS@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_3862897_8	1380394.JADL01000008_gene3467	1.175e-88	298.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria,2JQ14@204441|Rhodospirillales	204441|Rhodospirillales	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PYH1_k127_3862897_1	1205680.CAKO01000040_gene1074	9.002e-277	876.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JQSU@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
PYH1_k127_3862897_12	580332.Slit_2175	3.969e-21	98.0	COG3678@1|root,COG3678@2|Bacteria,1N2D7@1224|Proteobacteria,2VU8P@28216|Betaproteobacteria	28216|Betaproteobacteria	NPTU	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
PYH1_k127_3862897_11	1123060.JONP01000002_gene1004	3.229e-24	111.0	2DRIX@1|root,33BZB@2|Bacteria,1NM8A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3865093_1	76114.ebA4743	1.527e-241	750.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,2KVBW@206389|Rhodocyclales	206389|Rhodocyclales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
PYH1_k127_3865093_29	582744.Msip34_2320	3.205e-52	187.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,2KMW7@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PYH1_k127_3865093_28	323848.Nmul_A0721	2.346e-52	186.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2VSJ0@28216|Betaproteobacteria,373BC@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
PYH1_k127_3865093_22	1150469.RSPPHO_00403	1.859e-74	259.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,2JR8D@204441|Rhodospirillales	204441|Rhodospirillales	T	Universal stress protein UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH1_k127_3865093_21	859657.RPSI07_mp0045	1.124e-78	270.0	2B47E@1|root,31WYM@2|Bacteria,1R5Q0@1224|Proteobacteria,2VT47@28216|Betaproteobacteria,1K96G@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3865093_20	398767.Glov_0956	2.182e-79	289.0	2AAQ3@1|root,31026@2|Bacteria,1PN2B@1224|Proteobacteria,4313Y@68525|delta/epsilon subdivisions,2WWKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3865093_10	648757.Rvan_3533	1.501e-117	386.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
PYH1_k127_3865093_30	234267.Acid_4411	4.814e-45	168.0	COG0640@1|root,COG0640@2|Bacteria,3Y5ZP@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
PYH1_k127_3865093_34	1230476.C207_06068	1.144e-30	124.0	COG5470@1|root,COG5470@2|Bacteria,1RBBV@1224|Proteobacteria,2U5CX@28211|Alphaproteobacteria,3JY7T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
PYH1_k127_3865093_5	1266925.JHVX01000003_gene405	2.671e-209	679.0	COG1330@1|root,COG2887@1|root,COG1330@2|Bacteria,COG2887@2|Bacteria,1QU90@1224|Proteobacteria,2VHNR@28216|Betaproteobacteria,37212@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	PDDEXK_1
PYH1_k127_3865093_33	1120983.KB894574_gene1004	1.737e-40	156.0	COG1225@1|root,COG1225@2|Bacteria,1RA5K@1224|Proteobacteria,2U6EF@28211|Alphaproteobacteria,1JQAX@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
PYH1_k127_3865093_0	1288494.EBAPG3_21040	3.695e-265	847.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VHNB@28216|Betaproteobacteria,371VU@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
PYH1_k127_3865093_17	1122613.ATUP01000001_gene2020	8.982e-96	327.0	COG0627@1|root,COG0627@2|Bacteria,1QIRQ@1224|Proteobacteria,2TUU5@28211|Alphaproteobacteria,43Z22@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
PYH1_k127_3865093_2	1095769.CAHF01000011_gene2202	6.153e-241	755.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,472Z0@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	ABC transporter	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
PYH1_k127_3865093_8	1168059.KB899087_gene2747	3.953e-123	423.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,3EYFN@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Cysteine synthase A	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH1_k127_3865093_23	1163617.SCD_n01867	6.778e-70	247.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,2VM81@28216|Betaproteobacteria	28216|Betaproteobacteria	S	hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
PYH1_k127_3865093_9	378806.STAUR_1763	2.669e-118	391.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,43DXX@68525|delta/epsilon subdivisions,2X916@28221|Deltaproteobacteria,2Z1EC@29|Myxococcales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
PYH1_k127_3865093_6	331869.BAL199_28165	3.939e-195	621.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
PYH1_k127_3865093_13	1122604.JONR01000006_gene2711	2.013e-110	385.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1X33N@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
PYH1_k127_3865093_15	1094980.Mpsy_0015	6.457e-101	346.0	COG2133@1|root,COG3794@1|root,arCOG10180@1|root,arCOG02796@2157|Archaea,arCOG02929@2157|Archaea,arCOG10180@2157|Archaea,2XT1Q@28890|Euryarchaeota,2NADP@224756|Methanomicrobia	224756|Methanomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
PYH1_k127_3865093_16	187272.Mlg_2775	1.951e-97	330.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1WXWQ@135613|Chromatiales	135613|Chromatiales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
PYH1_k127_3865093_26	338969.Rfer_0847	6.689e-63	226.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2VS54@28216|Betaproteobacteria,4AE2P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
PYH1_k127_3865093_27	1211114.ALIP01000083_gene1541	5.621e-61	215.0	COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
PYH1_k127_3865093_24	1429916.X566_05595	3.564e-69	246.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3JTZB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_3865093_7	1297863.APJF01000013_gene3998	2.794e-124	421.0	COG2043@1|root,COG2043@2|Bacteria,1NR18@1224|Proteobacteria,2TVGP@28211|Alphaproteobacteria,3JU0D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterised ArCR, COG2043	MA20_36865	-	-	-	-	-	-	-	-	-	-	-	DUF169
PYH1_k127_3865093_32	748247.AZKH_0155	1.785e-41	160.0	2CESE@1|root,32S0D@2|Bacteria,1RHTD@1224|Proteobacteria,2VSJ5@28216|Betaproteobacteria,2KWQC@206389|Rhodocyclales	206389|Rhodocyclales	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA,Gly-zipper_YMGG
PYH1_k127_3865093_35	261292.Nit79A3_1540	1.012e-21	99.0	2DP14@1|root,3303I@2|Bacteria,1N7JW@1224|Proteobacteria,2VW7N@28216|Betaproteobacteria,373MI@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3865093_14	580332.Slit_0314	3.677e-106	359.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
PYH1_k127_3865093_36	1380394.JADL01000005_gene5408	1.07e-08	62.0	2DP14@1|root,3303I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_3865093_3	1288494.EBAPG3_22740	2.833e-231	729.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2VJEQ@28216|Betaproteobacteria,372MX@32003|Nitrosomonadales	28216|Betaproteobacteria	G	BT1 family	-	-	-	-	-	-	-	-	-	-	-	-	BT1
PYH1_k127_3865093_19	1123256.KB907945_gene349	3.031e-82	280.0	COG0546@1|root,COG0546@2|Bacteria,1Q5AX@1224|Proteobacteria,1RRNJ@1236|Gammaproteobacteria,1X9C4@135614|Xanthomonadales	135614|Xanthomonadales	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
PYH1_k127_3865093_25	999541.bgla_2g18460	2.266e-66	235.0	COG0220@1|root,COG0220@2|Bacteria,1QTX5@1224|Proteobacteria,2WH0A@28216|Betaproteobacteria,1K3DS@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
PYH1_k127_3865093_11	365044.Pnap_4013	6.541e-117	397.0	COG2831@1|root,COG2831@2|Bacteria,1PRBP@1224|Proteobacteria,2VHDS@28216|Betaproteobacteria,4A9SS@80864|Comamonadaceae	28216|Betaproteobacteria	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA,POTRA_2,ShlB
PYH1_k127_3865093_12	1349767.GJA_3586	4.61e-112	397.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
PYH1_k127_3865093_31	1144342.PMI40_04736	1.03e-42	171.0	COG4254@1|root,COG4254@2|Bacteria,1R2K9@1224|Proteobacteria,2WICR@28216|Betaproteobacteria,4796C@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
PYH1_k127_3865093_18	1123072.AUDH01000002_gene2408	1.687e-91	312.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JSUV@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_3865093_4	543728.Vapar_3215	3.126e-214	694.0	COG1053@1|root,COG1053@2|Bacteria,1QWW9@1224|Proteobacteria,2VPPG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
PYH1_k127_3971737_7	1163617.SCD_n01165	2.638e-76	262.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
PYH1_k127_3971737_8	640081.Dsui_2483	3.733e-75	260.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,2KVQS@206389|Rhodocyclales	206389|Rhodocyclales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PYH1_k127_3971737_9	748280.NH8B_1079	6.185e-68	234.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2VR4W@28216|Betaproteobacteria,2KR3R@206351|Neisseriales	206351|Neisseriales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
PYH1_k127_3971737_6	388051.AUFE01000010_gene2618	4.162e-82	281.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,1K069@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
PYH1_k127_3971737_0	1121004.ATVC01000002_gene564	2.459e-271	842.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VIJ8@28216|Betaproteobacteria,2KQG8@206351|Neisseriales	206351|Neisseriales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_3971737_5	1366050.N234_04095	1.181e-82	286.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2VIP5@28216|Betaproteobacteria,1K20F@119060|Burkholderiaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	fadB3	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_3971737_2	404589.Anae109_1599	7.145e-116	398.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,42QTW@68525|delta/epsilon subdivisions,2WMNU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Major facilitator superfamily MFS_1	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
PYH1_k127_3971737_1	935261.JAGL01000001_gene1771	1.612e-117	383.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2TTCE@28211|Alphaproteobacteria,43HHZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_3971737_3	316056.RPC_2954	1.196e-114	373.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria,3JT2Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	MA20_27855	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_3971737_4	1411123.JQNH01000001_gene2798	1.253e-96	321.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2TRWV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_3972762_3	69279.BG36_15875	5.876e-66	232.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,2TWD1@28211|Alphaproteobacteria,43QW5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PYH1_k127_3972762_2	1095769.CAHF01000018_gene818	8.988e-86	299.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VITW@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_3972762_1	312153.Pnuc_2043	1.39e-122	403.0	COG2267@1|root,COG2267@2|Bacteria,1MV7P@1224|Proteobacteria,2VPTY@28216|Betaproteobacteria,1K6GQ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
PYH1_k127_3972762_0	909943.HIMB100_00013150	2.943e-216	684.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,4BPPN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	ABC transporter	chvD	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
PYH1_k127_3972762_4	1207063.P24_14519	9.268e-15	87.0	COG1063@1|root,COG1063@2|Bacteria,1QTU5@1224|Proteobacteria,2TW9Q@28211|Alphaproteobacteria,2JQP9@204441|Rhodospirillales	204441|Rhodospirillales	E	Alanine dehydrogenase/PNT, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_3985458_4	323848.Nmul_A1843	3.79e-31	123.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,3722B@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
PYH1_k127_3985458_5	292415.Tbd_1119	6.402e-29	128.0	2B1HQ@1|root,31TYQ@2|Bacteria,1MYSE@1224|Proteobacteria,2VTMU@28216|Betaproteobacteria,1KSAH@119069|Hydrogenophilales	119069|Hydrogenophilales	S	CNP1-like family	-	-	-	-	-	-	-	-	-	-	-	-	CNP1
PYH1_k127_3985458_3	1266925.JHVX01000009_gene52	2.889e-71	248.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,2VQUX@28216|Betaproteobacteria,372TE@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
PYH1_k127_3985458_2	748247.AZKH_1050	1.649e-76	259.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,2KYR2@206389|Rhodocyclales	206389|Rhodocyclales	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PYH1_k127_3985458_1	640081.Dsui_1325	2.97e-86	287.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,2KU7I@206389|Rhodocyclales	206389|Rhodocyclales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
PYH1_k127_3985458_0	522306.CAP2UW1_3010	1.872e-255	797.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,1KPQK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
PYH1_k127_4003832_8	497321.C664_09285	1.702e-82	283.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,2VIZ8@28216|Betaproteobacteria,2KVMB@206389|Rhodocyclales	206389|Rhodocyclales	S	Beta-lactamase	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
PYH1_k127_4003832_12	596153.Alide_1591	6.29e-49	184.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2VIXW@28216|Betaproteobacteria,4AAQ9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Hemerythrin,PNP_phzG_C,Putative_PNPOx
PYH1_k127_4003832_3	331869.BAL199_22132	8.12e-117	385.0	COG4857@1|root,COG4857@2|Bacteria,1MXBW@1224|Proteobacteria,2TR0Z@28211|Alphaproteobacteria,4BRV5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
PYH1_k127_4003832_2	751994.AGIG01000034_gene578	3.913e-145	486.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1J4TX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PYH1_k127_4003832_0	1205680.CAKO01000038_gene1645	7.606e-234	760.0	28JZQ@1|root,2Z9PN@2|Bacteria,1N2WN@1224|Proteobacteria,2U0QD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4003832_13	666685.R2APBS1_2752	1.884e-42	160.0	2E31J@1|root,32Y1Y@2|Bacteria,1N745@1224|Proteobacteria,1SCMM@1236|Gammaproteobacteria,1X8QA@135614|Xanthomonadales	135614|Xanthomonadales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
PYH1_k127_4003832_9	189753.AXAS01000041_gene2534	1.341e-81	282.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_4003832_10	381666.H16_B1610	1.875e-67	246.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,2VIQD@28216|Betaproteobacteria,1K18U@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH1_k127_4003832_6	85643.Tmz1t_3131	3.688e-97	323.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,2VHGT@28216|Betaproteobacteria,2KZYM@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_4003832_7	748247.AZKH_2155	9.201e-86	293.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2VKUM@28216|Betaproteobacteria,2KY9I@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_4003832_5	62928.azo3048	2.507e-102	355.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VK9Y@28216|Betaproteobacteria,2KV1M@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_4003832_4	76114.ebA5304	4.266e-116	400.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,2KXZ1@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_4003832_1	296591.Bpro_2984	5.763e-160	516.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2VIK5@28216|Betaproteobacteria,4ABK8@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_4003832_11	595537.Varpa_4147	1.944e-51	186.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,4A9RV@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	iorB2	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
PYH1_k127_4013987_0	1123367.C666_01550	0.0	1307.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KVJB@206389|Rhodocyclales	206389|Rhodocyclales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
PYH1_k127_4013987_3	640081.Dsui_3032	3.901e-179	572.0	COG0280@1|root,COG2030@1|root,COG0280@2|Bacteria,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,2WGKC@28216|Betaproteobacteria,2KV8I@206389|Rhodocyclales	206389|Rhodocyclales	CI	Bifunctional enoyl-CoA hydratase phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas,PTA_PTB
PYH1_k127_4013987_2	85643.Tmz1t_4034	2.573e-218	690.0	COG1021@1|root,COG1021@2|Bacteria,1NSN8@1224|Proteobacteria,2WGU9@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_4013987_1	76114.ebA2099	0.0	1071.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VZ75@28216|Betaproteobacteria,2KXX2@206389|Rhodocyclales	206389|Rhodocyclales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
PYH1_k127_4013987_7	1244869.H261_18110	3.078e-13	78.0	2EGIY@1|root,33AB5@2|Bacteria,1NPCU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4013987_4	1267005.KB911256_gene1535	5.048e-40	153.0	COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,2U9DU@28211|Alphaproteobacteria,3N7AW@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
PYH1_k127_4013987_6	566466.NOR53_3032	1.645e-31	132.0	COG2050@1|root,COG2050@2|Bacteria,1RKWK@1224|Proteobacteria,1S6SH@1236|Gammaproteobacteria,1JATP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
PYH1_k127_4013987_5	706587.Desti_1835	2.458e-32	128.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2MS4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
PYH1_k127_4062928_2	1123368.AUIS01000007_gene2814	3.011e-85	292.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
PYH1_k127_4062928_0	1007105.PT7_0956	4.507e-122	413.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,2W0AM@28216|Betaproteobacteria,3T617@506|Alcaligenaceae	28216|Betaproteobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
PYH1_k127_4062928_6	94624.Bpet1726	8.553e-24	114.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,3T3UE@506|Alcaligenaceae	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
PYH1_k127_4062928_1	768671.ThimaDRAFT_0773	1.05e-87	301.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1WW35@135613|Chromatiales	135613|Chromatiales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
PYH1_k127_4062928_3	323848.Nmul_A2703	3.857e-54	193.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,37352@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
PYH1_k127_4062928_5	1469245.JFBG01000056_gene2461	3.986e-25	111.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1X1FH@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH1_k127_4062928_4	62928.azo1432	1.541e-33	130.0	COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,2VU50@28216|Betaproteobacteria,2KWXY@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
PYH1_k127_4079094_6	1120948.KB903243_gene2303	7.317e-14	83.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4E2MB@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
PYH1_k127_4079094_2	272560.BPSL0799	3.521e-134	446.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,1K26Y@119060|Burkholderiaceae	28216|Betaproteobacteria	F	phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
PYH1_k127_4079094_3	1411123.JQNH01000001_gene2532	1.699e-125	411.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TSIV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	fructose-bisphosphate aldolase	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
PYH1_k127_4079094_1	522306.CAP2UW1_1014	1.27e-166	535.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KQIU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
PYH1_k127_4079094_0	1123487.KB892841_gene4249	6.052e-304	941.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,2KUXJ@206389|Rhodocyclales	206389|Rhodocyclales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
PYH1_k127_4079094_4	398578.Daci_3588	7.842e-97	326.0	COG3181@1|root,COG3181@2|Bacteria,1NR8P@1224|Proteobacteria,2W16Z@28216|Betaproteobacteria,4AGPI@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_4079094_5	1403819.BATR01000130_gene4600	2.346e-94	314.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PYH1_k127_408972_3	1454004.AW11_00156	5.683e-92	307.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,1KPXM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
PYH1_k127_408972_6	1000565.METUNv1_03628	1.178e-61	227.0	28TB7@1|root,2ZFJR@2|Bacteria,1PACM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_408972_5	85643.Tmz1t_0698	6.668e-67	245.0	COG2267@1|root,COG2267@2|Bacteria,1QVBZ@1224|Proteobacteria,2VNI1@28216|Betaproteobacteria,2KUFT@206389|Rhodocyclales	206389|Rhodocyclales	I	Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6
PYH1_k127_408972_2	1411123.JQNH01000001_gene964	9.047e-94	312.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	MA20_22025	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
PYH1_k127_408972_1	472759.Nhal_3357	2.007e-134	463.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1WXK2@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH1_k127_408972_0	580332.Slit_2078	8.537e-154	495.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,44V5Z@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH1_k127_408972_4	1123393.KB891317_gene2481	2.986e-91	305.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VKEW@28216|Betaproteobacteria,1KRJK@119069|Hydrogenophilales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH1_k127_4118004_0	1366050.N234_32845	1.685e-117	383.0	COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2VH1W@28216|Betaproteobacteria,1KD0R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cytochrome D1 heme domain	nirF	-	-	ko:K19345	-	-	-	-	ko00000	-	-	-	Cytochrom_D1
PYH1_k127_4118004_2	34007.IT40_06615	1.514e-24	106.0	COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,2UGBE@28211|Alphaproteobacteria,2PXBE@265|Paracoccus	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	nirC	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K19344	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
PYH1_k127_4118004_1	323848.Nmul_A2313	6.4e-45	171.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,371WH@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
PYH1_k127_4120475_1	76114.ebA1038	2.358e-68	237.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,2KWHE@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the phosphoglycerate mutase family	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
PYH1_k127_4120475_0	1235457.C404_19490	6.365e-180	574.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,2VJHM@28216|Betaproteobacteria,1K46N@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Pfam:DUF1446	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
PYH1_k127_4170611_3	1131553.JIBI01000014_gene884	1.313e-60	222.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,372BP@32003|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
PYH1_k127_4170611_2	1000565.METUNv1_02110	1.23e-69	264.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,2KVJN@206389|Rhodocyclales	206389|Rhodocyclales	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,PNK3P
PYH1_k127_4170611_0	1123367.C666_07095	1.985e-200	644.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,2KUWE@206389|Rhodocyclales	206389|Rhodocyclales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
PYH1_k127_4170611_1	887898.HMPREF0551_0153	6.857e-158	508.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,1K1XK@119060|Burkholderiaceae	28216|Betaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
PYH1_k127_4170611_4	1454004.AW11_00172	2.73e-44	164.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,1KQF5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
PYH1_k127_4191306_6	1123368.AUIS01000008_gene2170	3.305e-77	263.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,1TD9U@1236|Gammaproteobacteria,2NCIW@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
PYH1_k127_4191306_8	640081.Dsui_1644	4.021e-31	127.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,2KWZ1@206389|Rhodocyclales	206389|Rhodocyclales	S	Invasion gene expression up-regulator SirB	sirB	-	-	-	-	-	-	-	-	-	-	-	SirB
PYH1_k127_4191306_9	159087.Daro_1050	9.212e-28	122.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria,2KX5X@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH1_k127_4191306_1	640081.Dsui_1650	3.4e-226	728.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,2KU93@206389|Rhodocyclales	206389|Rhodocyclales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
PYH1_k127_4191306_10	1459636.NTE_02207	9.076e-09	69.0	arCOG02763@1|root,arCOG02763@2157|Archaea	2157|Archaea	S	Heavy-metal-associated domain	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
PYH1_k127_4191306_5	1238182.C882_0258	2.176e-77	271.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
PYH1_k127_4191306_0	1123392.AQWL01000002_gene1978	0.0	1310.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSKV@119069|Hydrogenophilales	119069|Hydrogenophilales	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
PYH1_k127_4191306_7	543728.Vapar_4715	4.701e-47	171.0	COG0662@1|root,COG0662@2|Bacteria,1RH1E@1224|Proteobacteria,2VSQU@28216|Betaproteobacteria,4AEEV@80864|Comamonadaceae	28216|Betaproteobacteria	G	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH1_k127_4191306_4	1007105.PT7_0660	4.799e-103	347.0	COG1804@1|root,COG1804@2|Bacteria,1MWSJ@1224|Proteobacteria,2VPVP@28216|Betaproteobacteria,3T55N@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH1_k127_4191306_2	1217720.ALOX01000087_gene3010	1.715e-196	627.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2TR02@28211|Alphaproteobacteria,2JQR5@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_4191306_3	375286.mma_0010	2.168e-133	441.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria,476AX@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
PYH1_k127_4207425_2	1485544.JQKP01000001_gene904	2.618e-10	64.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,44VUX@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
PYH1_k127_4207425_1	1304883.KI912532_gene751	5.696e-109	361.0	2C5U9@1|root,318BZ@2|Bacteria,1RK4D@1224|Proteobacteria,2VKK4@28216|Betaproteobacteria,2KVF8@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
PYH1_k127_4207425_0	640081.Dsui_2415	1.005e-143	473.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,2KU7T@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PYH1_k127_4221685_3	329726.AM1_1088	5.294e-11	68.0	COG2095@1|root,COG2095@2|Bacteria,1G644@1117|Cyanobacteria	1117|Cyanobacteria	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
PYH1_k127_4221685_1	1095769.CAHF01000011_gene2277	5.515e-66	233.0	COG0625@1|root,COG0625@2|Bacteria,1RAP2@1224|Proteobacteria,2VQGV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
PYH1_k127_4221685_0	338969.Rfer_0646	5.922e-96	326.0	COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,2VP8F@28216|Betaproteobacteria,4AD6N@80864|Comamonadaceae	28216|Betaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH1_k127_4221685_2	596153.Alide_1776	3.576e-49	177.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VI1V@28216|Betaproteobacteria,4ABKZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_4248981_1	396588.Tgr7_3090	3.992e-131	426.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,1WXE4@135613|Chromatiales	135613|Chromatiales	J	Allophanate hydrolase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
PYH1_k127_4248981_7	1452718.JBOY01000063_gene2610	6.864e-18	96.0	COG3650@1|root,COG3650@2|Bacteria	2|Bacteria	CO	response to hydrogen peroxide	-	-	-	ko:K08985	-	-	-	-	ko00000	-	-	-	-
PYH1_k127_4248981_5	543913.D521_0739	8.52e-47	175.0	COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,2WG7R@28216|Betaproteobacteria,1KQVR@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
PYH1_k127_4248981_2	365046.Rta_14170	7.493e-102	342.0	COG3181@1|root,COG3181@2|Bacteria,1MYJX@1224|Proteobacteria,2VM8F@28216|Betaproteobacteria,4AC6J@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_4248981_0	1333998.M2A_2585	3.326e-144	478.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130,ko:K01138	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
PYH1_k127_4248981_6	237368.SCABRO_02034	7.418e-37	149.0	COG4642@1|root,COG4642@2|Bacteria	2|Bacteria	S	regulation of ryanodine-sensitive calcium-release channel activity	-	-	-	-	-	-	-	-	-	-	-	-	MORN
PYH1_k127_4248981_4	237368.SCABRO_02034	1.723e-50	186.0	COG4642@1|root,COG4642@2|Bacteria	2|Bacteria	S	regulation of ryanodine-sensitive calcium-release channel activity	-	-	-	-	-	-	-	-	-	-	-	-	MORN
PYH1_k127_4248981_8	1121441.AUCX01000010_gene100	0.0003092	49.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_32
PYH1_k127_4248981_3	189753.AXAS01000041_gene2534	5.904e-74	261.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_4261319_2	1380394.JADL01000001_gene1950	5.588e-33	145.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria,2JR8N@204441|Rhodospirillales	204441|Rhodospirillales	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
PYH1_k127_4261319_1	397945.Aave_4770	9.641e-108	361.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2VKPZ@28216|Betaproteobacteria,4AB3E@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
PYH1_k127_4261319_0	1123368.AUIS01000031_gene1422	2.81e-140	453.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PYH1_k127_4261319_3	1163617.SCD_n00026	3.98e-21	108.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
PYH1_k127_4268247_2	497321.C664_09700	8.867e-96	332.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2VHB6@28216|Betaproteobacteria,2KUMZ@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
PYH1_k127_4268247_1	76114.ebA4050	1.032e-101	349.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VNV2@28216|Betaproteobacteria,2KUPV@206389|Rhodocyclales	206389|Rhodocyclales	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
PYH1_k127_4268247_0	640511.BC1002_1896	9.637e-181	589.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,2VJ3Y@28216|Betaproteobacteria,1K165@119060|Burkholderiaceae	28216|Betaproteobacteria	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
PYH1_k127_4268247_3	305700.B447_08218	1.22e-50	188.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,2KUU4@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
PYH1_k127_4310293_4	395495.Lcho_1708	4.015e-79	301.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,2VP38@28216|Betaproteobacteria,1KN8D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
PYH1_k127_4310293_0	522306.CAP2UW1_2826	0.0	1024.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KQAC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	SNARE associated Golgi protein	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
PYH1_k127_4310293_2	472759.Nhal_1112	5.214e-146	468.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RN94@1236|Gammaproteobacteria,1WXKU@135613|Chromatiales	135613|Chromatiales	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
PYH1_k127_4310293_6	887898.HMPREF0551_1669	1.605e-30	137.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,2VX3A@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
PYH1_k127_4310293_5	1504672.669784583	1.852e-42	177.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,2VRZJ@28216|Betaproteobacteria,4AF81@80864|Comamonadaceae	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH1_k127_4310293_1	395495.Lcho_0940	2.156e-171	545.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,1KJN3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
PYH1_k127_4310293_3	983917.RGE_07870	8.268e-124	404.0	COG0466@1|root,COG0466@2|Bacteria,1MWQ9@1224|Proteobacteria,2VJKY@28216|Betaproteobacteria,1KJEZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
PYH1_k127_4326734_8	1304883.KI912532_gene598	7.372e-43	160.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,2KV4A@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
PYH1_k127_4326734_3	522306.CAP2UW1_4173	3.098e-109	366.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,1KPNT@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
PYH1_k127_4326734_7	1123393.KB891316_gene1886	1.843e-45	169.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,1KT0K@119069|Hydrogenophilales	119069|Hydrogenophilales	S	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2
PYH1_k127_4326734_4	1163617.SCD_n00308	5.04e-102	350.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Lipid A Biosynthesis	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
PYH1_k127_4326734_6	1163617.SCD_n00308	3.149e-84	287.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Lipid A Biosynthesis	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
PYH1_k127_4326734_1	580332.Slit_0177	2.98e-185	602.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,44VJJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
PYH1_k127_4326734_0	378806.STAUR_6282	1.023e-255	796.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2YU8Q@29|Myxococcales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
PYH1_k127_4326734_2	323848.Nmul_A2539	2.008e-128	415.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria,3728C@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
PYH1_k127_4326734_5	580332.Slit_2048	1.913e-100	339.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VMQU@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
PYH1_k127_4329772_0	667632.KB890209_gene5426	0.0	1043.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,1K06P@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
PYH1_k127_4382286_4	1163617.SCD_n01163	1.737e-109	378.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	dppF	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_4382286_1	1266925.JHVX01000010_gene1322	3.182e-167	537.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,372BM@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH1_k127_4382286_2	522306.CAP2UW1_3046	1.4e-161	513.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,1KQYZ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH1_k127_4382286_0	1304883.KI912532_gene2985	2.528e-293	930.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,2KU6I@206389|Rhodocyclales	206389|Rhodocyclales	E	extracellular solute-binding protein	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
PYH1_k127_4382286_3	123899.JPQP01000019_gene2724	6.56e-114	381.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VIHE@28216|Betaproteobacteria,3T1RP@506|Alcaligenaceae	28216|Betaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH1_k127_4382286_5	1286093.C266_21819	2.929e-09	60.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1K2ZM@119060|Burkholderiaceae	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
PYH1_k127_4411764_1	640511.BC1002_1427	1.402e-72	253.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VQB8@28216|Betaproteobacteria,1KGNC@119060|Burkholderiaceae	28216|Betaproteobacteria	K	transcriptional Regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH1_k127_4411764_0	1095769.CAHF01000014_gene2999	0.0	1591.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,472T4@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
PYH1_k127_4452835_3	1040989.AWZU01000035_gene1779	2.197e-12	68.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,3JT6H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Malic enzyme, NAD binding domain	MA20_02490	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
PYH1_k127_4452835_2	640081.Dsui_0871	3.596e-20	94.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,2KX05@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
PYH1_k127_4452835_0	1163617.SCD_n02060	1.955e-87	299.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria	1224|Proteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2
PYH1_k127_4452835_1	292415.Tbd_2547	2.327e-83	301.0	2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,2VZZT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4462463_5	1163398.AJJP01000075_gene2559	0.0002488	47.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1R4Z6@1224|Proteobacteria	1224|Proteobacteria	Q	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4462463_2	1123504.JQKD01000003_gene638	1.968e-162	521.0	COG0179@1|root,COG0179@2|Bacteria,1MW82@1224|Proteobacteria,2VJAE@28216|Betaproteobacteria,4ACVI@80864|Comamonadaceae	28216|Betaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
PYH1_k127_4462463_1	246197.MXAN_2787	2.621e-189	599.0	COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,42Z7C@68525|delta/epsilon subdivisions,2WTZE@28221|Deltaproteobacteria,2YY2N@29|Myxococcales	28221|Deltaproteobacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
PYH1_k127_4462463_3	1408437.JNJN01000002_gene1403	4.43e-16	83.0	COG3041@1|root,COG3041@2|Bacteria,1VENE@1239|Firmicutes,24MW1@186801|Clostridia	186801|Clostridia	S	addiction module toxin, RelE StbE family	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
PYH1_k127_4462463_4	5932.XP_004027221.1	1.286e-13	84.0	COG4642@1|root,COG5253@1|root,KOG0229@2759|Eukaryota,KOG0231@2759|Eukaryota	2759|Eukaryota	DZ	MORN repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN
PYH1_k127_4462463_0	29581.BW37_00136	1.977e-215	701.0	COG0671@1|root,COG0671@2|Bacteria,1QUY3@1224|Proteobacteria,2WGK5@28216|Betaproteobacteria,475ZI@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Exopolysaccharide biosynthesis protein YbjH	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,YjbH
PYH1_k127_4467559_18	452637.Oter_3993	2.172e-69	244.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
PYH1_k127_4467559_5	1123504.JQKD01000011_gene2361	3.586e-174	556.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2WEXA@28216|Betaproteobacteria,4A9KB@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
PYH1_k127_4467559_27	522306.CAP2UW1_1845	1.187e-28	121.0	COG5010@1|root,COG5010@2|Bacteria,1R0QI@1224|Proteobacteria,2VX62@28216|Betaproteobacteria,1KR08@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4467559_25	296591.Bpro_2056	6.384e-42	179.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
PYH1_k127_4467559_19	1121004.ATVC01000059_gene661	9.906e-65	234.0	COG0596@1|root,COG0596@2|Bacteria,1QUVT@1224|Proteobacteria,2WGRR@28216|Betaproteobacteria,2KR10@206351|Neisseriales	206351|Neisseriales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
PYH1_k127_4467559_20	318996.AXAZ01000008_gene4295	1.667e-60	221.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_4467559_2	1198452.Jab_1c19770	3.399e-228	742.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,475DR@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE2,PAS_4,PAS_9
PYH1_k127_4467559_29	216142.LT40_21060	3.314e-10	71.0	2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,1S9NM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4467559_14	396588.Tgr7_3067	4.785e-84	286.0	COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,1RR95@1236|Gammaproteobacteria,1WVUK@135613|Chromatiales	135613|Chromatiales	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
PYH1_k127_4467559_28	76114.ebA6177	3.314e-21	96.0	2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,2VW2I@28216|Betaproteobacteria,2KX73@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3301
PYH1_k127_4467559_26	671143.DAMO_2594	3.18e-34	148.0	COG0745@1|root,COG0745@2|Bacteria	671143.DAMO_2594|-	T	phosphorelay signal transduction system	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
PYH1_k127_4467559_11	420324.KI912061_gene6194	2.05e-119	437.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria,1JXBR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
PYH1_k127_4467559_0	1298867.AUES01000067_gene5125	6.409e-265	898.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3JS5D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_7,dCache_1
PYH1_k127_4467559_21	1121861.KB899911_gene1390	4.575e-58	210.0	COG0251@1|root,COG0251@2|Bacteria,1N1B6@1224|Proteobacteria,2TZWE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4467559_9	1207063.P24_16355	4.521e-129	420.0	COG4177@1|root,COG4177@2|Bacteria,1PAW4@1224|Proteobacteria,2U0EY@28211|Alphaproteobacteria,2JZAV@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH1_k127_4467559_10	1207063.P24_16360	1.782e-127	422.0	COG0559@1|root,COG0559@2|Bacteria,1R5H9@1224|Proteobacteria,2TUJ6@28211|Alphaproteobacteria,2JVT7@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH1_k127_4467559_13	331869.BAL199_24464	1.976e-102	350.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria,4BT78@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	MA20_02445	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_4467559_12	331869.BAL199_24469	2.328e-112	367.0	COG0411@1|root,COG0411@2|Bacteria,1R7BP@1224|Proteobacteria,2U3BF@28211|Alphaproteobacteria,4BS0A@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_4467559_4	1207063.P24_16375	3.226e-208	662.0	COG0683@1|root,COG0683@2|Bacteria,1Q1P3@1224|Proteobacteria,2TUJG@28211|Alphaproteobacteria,2JVUV@204441|Rhodospirillales	204441|Rhodospirillales	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH1_k127_4467559_24	1121861.KB899917_gene3618	1.302e-43	176.0	2BQVQ@1|root,32JSN@2|Bacteria,1RJK4@1224|Proteobacteria,2UAA6@28211|Alphaproteobacteria,2JXH7@204441|Rhodospirillales	204441|Rhodospirillales	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
PYH1_k127_4467559_3	1380394.JADL01000009_gene3164	9.262e-212	669.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JPPV@204441|Rhodospirillales	204441|Rhodospirillales	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
PYH1_k127_4467559_17	1033802.SSPSH_000945	9.532e-75	267.0	COG1028@1|root,COG1028@2|Bacteria,1PEWK@1224|Proteobacteria,1RXZH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_4467559_6	1408164.MOLA814_01669	1.556e-149	480.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2VM8X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
PYH1_k127_4467559_23	1206101.AZXC01000012_gene1237	4.008e-51	185.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
PYH1_k127_4467559_15	1158292.JPOE01000002_gene2084	3.758e-81	284.0	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,2VJ9I@28216|Betaproteobacteria,1KKZS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_4467559_22	686340.Metal_2551	1.184e-57	207.0	COG0860@1|root,COG0860@2|Bacteria,1RJBG@1224|Proteobacteria	1224|Proteobacteria	M	Cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
PYH1_k127_4467559_16	864051.BurJ1DRAFT_0525	9.836e-78	269.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2VJC1@28216|Betaproteobacteria,1KITU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_4467559_1	987059.RBXJA2T_04138	2.551e-258	805.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,1KIY7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_4467559_8	1110502.TMO_0637	2.341e-131	431.0	COG0683@1|root,COG0683@2|Bacteria,1MWH7@1224|Proteobacteria,2TS8K@28211|Alphaproteobacteria,2JW94@204441|Rhodospirillales	204441|Rhodospirillales	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_4467559_7	1366050.N234_07585	1.126e-135	437.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VJAM@28216|Betaproteobacteria,1K1W7@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_4491872_3	1392838.AWNM01000018_gene3450	2.652e-30	124.0	COG1024@1|root,COG1024@2|Bacteria,1NJ9M@1224|Proteobacteria	1224|Proteobacteria	I	Enoyl-CoA hydratase	MA20_29580	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_4491872_2	1265502.KB905935_gene3068	1.098e-66	230.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,4ADHY@80864|Comamonadaceae	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
PYH1_k127_4491872_0	1123487.KB892841_gene4321	8.938e-158	512.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,2KVXU@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
PYH1_k127_4491872_1	640081.Dsui_3144	1.401e-67	239.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,2KW79@206389|Rhodocyclales	206389|Rhodocyclales	NU	type 4 pilus biogenesis protein	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_2,TPR_8
PYH1_k127_4491872_4	395494.Galf_1395	3.924e-14	84.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,44VYD@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
PYH1_k127_4495051_0	795666.MW7_1298	0.0	1360.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1K16W@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
PYH1_k127_4505592_0	1123368.AUIS01000015_gene2639	4.609e-127	419.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,2NCSD@225057|Acidithiobacillales	225057|Acidithiobacillales	MV	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH1_k127_4505592_1	1249627.D779_2094	6.418e-108	367.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,1WWIJ@135613|Chromatiales	135613|Chromatiales	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
PYH1_k127_4505592_3	76114.ebA6529	8.948e-46	177.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria,2KUCN@206389|Rhodocyclales	206389|Rhodocyclales	EG	Solute carrier family 35	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_4505592_2	1380394.JADL01000003_gene5182	2.382e-83	283.0	COG2267@1|root,COG2267@2|Bacteria,1NK3M@1224|Proteobacteria,2TRP8@28211|Alphaproteobacteria,2JS7D@204441|Rhodospirillales	204441|Rhodospirillales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_4505592_4	1205680.CAKO01000010_gene3994	6.015e-43	162.0	COG2271@1|root,COG2271@2|Bacteria,1QU9E@1224|Proteobacteria,2TWHH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_4517109_2	338966.Ppro_3460	4.678e-61	221.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,43AN8@68525|delta/epsilon subdivisions,2X62F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
PYH1_k127_4517109_1	156889.Mmc1_1921	1.113e-90	319.0	COG0515@1|root,COG1262@1|root,COG3170@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG3170@2|Bacteria,1PJRR@1224|Proteobacteria,2U625@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF4189,PG_binding_1,Pkinase,WD40
PYH1_k127_4517109_4	1157708.KB907466_gene659	2.344e-26	115.0	2CH9M@1|root,332CJ@2|Bacteria,1N7TS@1224|Proteobacteria,2VX3H@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4517109_3	1173028.ANKO01000065_gene5658	1.203e-37	156.0	COG3265@1|root,COG3265@2|Bacteria,1G60D@1117|Cyanobacteria,1HBNQ@1150|Oscillatoriales	1117|Cyanobacteria	F	TIGRFAM Carbohydrate kinase, thermoresistant glucokinase	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	SKI
PYH1_k127_4517109_0	1123368.AUIS01000009_gene2502	5.649e-104	342.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,2NBSK@225057|Acidithiobacillales	225057|Acidithiobacillales	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
PYH1_k127_4536055_17	379066.GAU_2777	1.475e-06	55.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
PYH1_k127_4536055_12	640081.Dsui_3530	2.606e-75	257.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria,2KW6F@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PYH1_k127_4536055_0	1266925.JHVX01000003_gene647	2.451e-308	954.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,372AD@32003|Nitrosomonadales	28216|Betaproteobacteria	H	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_4536055_13	1121035.AUCH01000007_gene561	2.921e-74	257.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,2KV5Y@206389|Rhodocyclales	206389|Rhodocyclales	E	Acetolactate synthase small	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
PYH1_k127_4536055_3	1265502.KB905935_gene3131	1.155e-180	570.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,4AB67@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
PYH1_k127_4536055_7	228410.NE1322	2.771e-92	307.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2VHHT@28216|Betaproteobacteria,3728F@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
PYH1_k127_4536055_6	882378.RBRH_02513	2.189e-110	362.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,1JZXY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
PYH1_k127_4536055_9	305700.B447_00570	3.589e-87	311.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,2KU72@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in response to NO	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
PYH1_k127_4536055_1	420662.Mpe_A2101	4.113e-246	768.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,1KJTS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
PYH1_k127_4536055_2	189753.AXAS01000006_gene2442	5.124e-215	682.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_8,TolB_N
PYH1_k127_4536055_15	1123392.AQWL01000001_gene1482	1.816e-33	138.0	COG3308@1|root,COG3308@2|Bacteria,1N1EF@1224|Proteobacteria,2VU3C@28216|Betaproteobacteria,1KRW6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Predicted membrane protein (DUF2069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2069
PYH1_k127_4536055_16	1380356.JNIK01000011_gene1693	5.474e-08	59.0	2F9A4@1|root,341M7@2|Bacteria,2ISUU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
PYH1_k127_4536055_10	1123393.KB891316_gene1278	1.791e-80	291.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2VJMC@28216|Betaproteobacteria,1KSQW@119069|Hydrogenophilales	119069|Hydrogenophilales	S	NADPH-dependent FMN reductase	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
PYH1_k127_4536055_8	1163617.SCD_n00827	1.072e-88	317.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	UPF0761 membrane protein	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
PYH1_k127_4536055_11	631362.Thi970DRAFT_04180	2.292e-79	291.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1WW0C@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
PYH1_k127_4536055_4	1049564.TevJSym_af00670	3.928e-139	472.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1J50C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Na+ dependent nucleoside transporter N-terminus	nupX	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
PYH1_k127_4536055_14	1232410.KI421428_gene1088	9.917e-56	199.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2WPHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
PYH1_k127_4536055_5	314278.NB231_13771	1.495e-125	411.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWP3@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
PYH1_k127_4538809_1	497321.C664_03325	1.652e-57	218.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,2KUS1@206389|Rhodocyclales	206389|Rhodocyclales	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
PYH1_k127_4538809_0	395494.Galf_2688	4.493e-95	325.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,44VAD@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PYH1_k127_4538809_2	1123487.KB892834_gene2763	2.2e-21	96.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,2KV4A@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
PYH1_k127_4541913_6	1120973.AQXL01000120_gene841	8.939e-30	132.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,279QM@186823|Alicyclobacillaceae	91061|Bacilli	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
PYH1_k127_4541913_2	257310.BB4477	8.05e-51	198.0	COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,2VTCP@28216|Betaproteobacteria,3T424@506|Alcaligenaceae	28216|Betaproteobacteria	E	Allophanate hydrolase subunit 1	kipI	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
PYH1_k127_4541913_1	266809.PM03_02835	6.986e-74	255.0	2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nitrile hydratase	nthA	-	4.2.1.84	ko:K01721,ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
PYH1_k127_4541913_4	1380394.JADL01000002_gene1249	1.862e-36	140.0	2DBV6@1|root,32TY6@2|Bacteria,1N0TC@1224|Proteobacteria,2UCAJ@28211|Alphaproteobacteria,2JXVR@204441|Rhodospirillales	204441|Rhodospirillales	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
PYH1_k127_4541913_5	1380394.JADL01000002_gene1250	3.735e-31	134.0	2DWFS@1|root,32V1J@2|Bacteria,1MZ9A@1224|Proteobacteria,2UDME@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
PYH1_k127_4541913_0	331869.BAL199_16353	5.413e-241	758.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,4BPZA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_4541913_3	1123237.Salmuc_04915	5.533e-38	150.0	COG3185@1|root,COG3185@2|Bacteria,1QXYZ@1224|Proteobacteria,2TY40@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
PYH1_k127_4546634_3	316067.Geob_3326	1.786e-67	264.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PQZ@68525|delta/epsilon subdivisions,2WMD9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Hemolysin-type calcium-binding	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HCBP_related,He_PIG,HemolysinCabind,Peptidase_M91,VWA_2
PYH1_k127_4546634_0	290397.Adeh_0221	1.211e-125	422.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,2Z0DM@29|Myxococcales	28221|Deltaproteobacteria	M	RmlD substrate binding domain	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
PYH1_k127_4546634_1	1304883.KI912532_gene1089	2.708e-97	333.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,2WGZN@28216|Betaproteobacteria,2KUGZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PYH1_k127_4546634_2	1121035.AUCH01000009_gene859	8.054e-94	317.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VPK7@28216|Betaproteobacteria,2KVC8@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
PYH1_k127_4546634_4	1158292.JPOE01000002_gene2991	4.418e-52	198.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,1KK38@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
PYH1_k127_4576605_7	62928.azo3138	9.9e-18	85.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,2KWRT@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the DnaA family	-	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
PYH1_k127_4576605_2	1123392.AQWL01000001_gene1461	8.107e-92	307.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,1KRKJ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
PYH1_k127_4576605_1	1304883.KI912532_gene3162	2.427e-165	541.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,2KV46@206389|Rhodocyclales	206389|Rhodocyclales	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
PYH1_k127_4576605_6	76114.ebA7113	9.771e-47	189.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,2KWMK@206389|Rhodocyclales	206389|Rhodocyclales	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
PYH1_k127_4576605_4	1095769.CAHF01000013_gene3343	6.986e-83	285.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,473B3@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
PYH1_k127_4576605_0	1097668.BYI23_C004060	3.439e-210	665.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VH8Z@28216|Betaproteobacteria,1JZW1@119060|Burkholderiaceae	28216|Betaproteobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
PYH1_k127_4576605_3	1095769.CAHF01000022_gene41	8.484e-88	300.0	COG1024@1|root,COG1024@2|Bacteria,1MUD7@1224|Proteobacteria,2VQ37@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Pfam Enoyl-CoA hydratase isomerase	-	-	-	ko:K13816	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	ECH_1
PYH1_k127_4576605_5	1095769.CAHF01000022_gene40	1.85e-71	248.0	COG5424@1|root,COG5424@2|Bacteria,1QVK0@1224|Proteobacteria	1224|Proteobacteria	H	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
PYH1_k127_4576605_8	396588.Tgr7_0082	1.675e-08	61.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2QR@135613|Chromatiales	135613|Chromatiales	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
PYH1_k127_4582184_14	331869.BAL199_28635	5.992e-42	167.0	COG1028@1|root,COG1028@2|Bacteria,1R3TE@1224|Proteobacteria,2U55K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_4582184_13	1000565.METUNv1_02493	6.244e-54	199.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,2KWCD@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
PYH1_k127_4582184_9	1182590.BN5_02952	1.193e-94	323.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1YEFP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
PYH1_k127_4582184_15	391735.Veis_3940	1.009e-35	141.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,4ADPE@80864|Comamonadaceae	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
PYH1_k127_4582184_16	1288494.EBAPG3_2710	3.067e-29	119.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,373G4@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
PYH1_k127_4582184_18	1499967.BAYZ01000060_gene5988	1.29e-13	73.0	2EQK7@1|root,33I68@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4582184_3	640081.Dsui_1322	2.545e-188	612.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,2KUVT@206389|Rhodocyclales	206389|Rhodocyclales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
PYH1_k127_4582184_11	1304883.KI912532_gene1510	2.006e-70	247.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,2KW12@206389|Rhodocyclales	206389|Rhodocyclales	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
PYH1_k127_4582184_5	1288494.EBAPG3_10560	5.322e-135	455.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria,372CM@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Domain of unknown function DUF21	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
PYH1_k127_4582184_1	1000565.METUNv1_02896	3.321e-240	755.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KUK3@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
PYH1_k127_4582184_2	640081.Dsui_1319	2.101e-197	622.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,2KUZY@206389|Rhodocyclales	206389|Rhodocyclales	U	type II secretion system protein	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
PYH1_k127_4582184_6	292415.Tbd_2368	6.219e-113	370.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,1KRR5@119069|Hydrogenophilales	119069|Hydrogenophilales	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
PYH1_k127_4582184_12	85643.Tmz1t_3656	6.748e-64	231.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,2KW4Z@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
PYH1_k127_4582184_8	1000565.METUNv1_00089	8.005e-108	356.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,2KUR3@206389|Rhodocyclales	206389|Rhodocyclales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
PYH1_k127_4582184_17	1121035.AUCH01000016_gene2151	2.547e-15	86.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,2KXJH@206389|Rhodocyclales	206389|Rhodocyclales	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
PYH1_k127_4582184_10	1163617.SCD_n02471	1.026e-88	320.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
PYH1_k127_4582184_7	93220.LV28_11400	1.011e-109	364.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2VID5@28216|Betaproteobacteria,1K3C5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SMART AAA ATPase	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
PYH1_k127_4582184_4	1163617.SCD_n02472	1.495e-148	505.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2VJ84@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
PYH1_k127_4582184_0	62928.azo0893	0.0	1283.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,2KVJC@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
PYH1_k127_4589769_0	420662.Mpe_A0874	6.183e-319	1023.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VHP1@28216|Betaproteobacteria,1KIU9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE1	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_C,Transketolase_N
PYH1_k127_4589769_6	1385519.N801_15195	9.597e-92	329.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
PYH1_k127_4589769_11	981384.AEYW01000023_gene3875	5.654e-50	202.0	COG0642@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2V7JS@28211|Alphaproteobacteria,4ND7E@97050|Ruegeria	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PYH1_k127_4589769_5	471852.Tcur_0033	4.543e-97	325.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4EICB@85012|Streptosporangiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
PYH1_k127_4589769_10	864051.BurJ1DRAFT_4626	5.926e-53	212.0	COG0386@1|root,COG0386@2|Bacteria,1RDR8@1224|Proteobacteria,2VQHV@28216|Betaproteobacteria,1KKWM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
PYH1_k127_4589769_2	313606.M23134_01996	1.556e-137	448.0	COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,47M0X@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_4589769_4	331869.BAL199_20735	8.318e-100	342.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2TSR4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4589769_8	1313172.YM304_29050	2.393e-82	308.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4CNTU@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
PYH1_k127_4589769_9	1382306.JNIM01000001_gene1022	4.475e-61	216.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PYH1_k127_4589769_1	1382306.JNIM01000001_gene1023	3.685e-263	841.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH1_k127_4589769_7	485913.Krac_2435	5.563e-89	330.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
PYH1_k127_4589769_3	365046.Rta_09170	1.108e-109	359.0	COG1028@1|root,COG1028@2|Bacteria,1MWJQ@1224|Proteobacteria,2VIQH@28216|Betaproteobacteria,4ACY5@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH1_k127_4589769_12	1380394.JADL01000002_gene1205	2.866e-20	105.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,2JQ8S@204441|Rhodospirillales	204441|Rhodospirillales	E	Glycine cleavage system T protein	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
PYH1_k127_459612_0	1163617.SCD_n01904	1.148e-151	488.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	N-Acetylmuramoyl-L-alanine amidase	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
PYH1_k127_459612_2	1163617.SCD_n02206	2.642e-71	253.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
PYH1_k127_459612_1	1163617.SCD_n01900	1.991e-119	394.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
PYH1_k127_459954_10	1095769.CAHF01000022_gene429	5.359e-57	203.0	COG2165@1|root,COG2165@2|Bacteria,1RGZZ@1224|Proteobacteria,2VSZ6@28216|Betaproteobacteria,4773W@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	prepilin-type N-terminal cleavage methylation	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
PYH1_k127_459954_11	1095769.CAHF01000022_gene430	2.763e-44	166.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria,474VB@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	prepilin-type N-terminal cleavage methylation	gspG4	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
PYH1_k127_459954_12	1123368.AUIS01000016_gene2543	5.165e-41	166.0	COG2165@1|root,COG2165@2|Bacteria,1MZ5I@1224|Proteobacteria,1SBEY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretory pathway pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_459954_1	936455.KI421499_gene5925	1.624e-241	758.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3JR0N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
PYH1_k127_459954_5	312153.Pnuc_0450	5.615e-94	329.0	COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,2WHGI@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_459954_3	1192124.LIG30_2013	1.396e-122	397.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,1K0P4@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaF	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH1_k127_459954_9	641491.DND132_1058	1.144e-58	211.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2WNV0@28221|Deltaproteobacteria,2MBI2@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM isochorismatase hydrolase	yddQ	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
PYH1_k127_459954_6	1122599.AUGR01000031_gene2	2.383e-79	273.0	COG0663@1|root,COG0663@2|Bacteria,1MVUI@1224|Proteobacteria,1RYPQ@1236|Gammaproteobacteria,1XHPR@135619|Oceanospirillales	135619|Oceanospirillales	S	Phenylacetic acid degradation protein PaaY	-	-	-	ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
PYH1_k127_459954_2	292.DM42_1304	4.093e-211	663.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria,1K11N@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
PYH1_k127_459954_7	221288.JH992901_gene2456	2.185e-69	261.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria,1JIE9@1189|Stigonemataceae	1117|Cyanobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
PYH1_k127_459954_8	883.DvMF_1949	2.484e-60	229.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,42VPN@68525|delta/epsilon subdivisions,2WRK6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_459954_0	1463901.JOIY01000009_gene2733	1.201e-241	764.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	fadH	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
PYH1_k127_459954_4	317619.ANKN01000038_gene66	2.414e-115	381.0	COG0714@1|root,COG0714@2|Bacteria,1G1CG@1117|Cyanobacteria,1MNN3@1212|Prochloraceae	1117|Cyanobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
PYH1_k127_459954_13	395493.BegalDRAFT_2160	1.656e-08	66.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,1RQSS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
PYH1_k127_4619428_10	1286093.C266_11640	1.025e-76	279.0	COG1073@1|root,COG1073@2|Bacteria,1QVY5@1224|Proteobacteria,2WGUH@28216|Betaproteobacteria,1K039@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DLH,FSH1,Hydrolase_4
PYH1_k127_4619428_0	640081.Dsui_3018	1.78e-214	674.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,2KVQ4@206389|Rhodocyclales	206389|Rhodocyclales	H	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
PYH1_k127_4619428_13	1163617.SCD_n02073	4.58e-41	158.0	2CCFR@1|root,2Z7VF@2|Bacteria,1MXHU@1224|Proteobacteria,2VHMR@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4619428_16	1458357.BG58_00495	2.949e-17	83.0	2E6W9@1|root,331FT@2|Bacteria,1N6E1@1224|Proteobacteria,2VVIR@28216|Betaproteobacteria,1K8KB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3567)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3567
PYH1_k127_4619428_7	765910.MARPU_09265	1.575e-86	299.0	COG1524@1|root,COG1524@2|Bacteria,1R2II@1224|Proteobacteria,1RQDZ@1236|Gammaproteobacteria,1X2CP@135613|Chromatiales	135613|Chromatiales	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
PYH1_k127_4619428_8	671143.DAMO_0872	2.243e-79	289.0	COG2267@1|root,COG2267@2|Bacteria,2NRR1@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
PYH1_k127_4619428_4	257310.BB1172	2.526e-128	422.0	COG2866@1|root,COG2866@2|Bacteria,1N6CX@1224|Proteobacteria,2VHWB@28216|Betaproteobacteria,3T1NN@506|Alcaligenaceae	28216|Betaproteobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
PYH1_k127_4619428_9	1500894.JQNN01000001_gene3513	1.285e-77	263.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,4723E@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
PYH1_k127_4619428_6	998674.ATTE01000001_gene394	2.325e-94	324.0	COG0477@1|root,COG2814@2|Bacteria,1QUY6@1224|Proteobacteria,1S2RA@1236|Gammaproteobacteria,463KE@72273|Thiotrichales	72273|Thiotrichales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_4619428_3	1366050.N234_12305	5.939e-160	537.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,1K400@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_4619428_15	391735.Veis_4250	3.508e-32	133.0	COG1917@1|root,COG1917@2|Bacteria,1N7QJ@1224|Proteobacteria,2VVHY@28216|Betaproteobacteria,4AFEU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cupin 2, conserved barrel	-	-	-	ko:K21700	-	-	-	-	ko00000	-	-	-	Cupin_2
PYH1_k127_4619428_12	1408164.MOLA814_02206	7.723e-48	176.0	2E5W4@1|root,330K6@2|Bacteria,1N893@1224|Proteobacteria,2VXF8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
PYH1_k127_4619428_1	296591.Bpro_3466	4.736e-172	546.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2VI04@28216|Betaproteobacteria,4AASZ@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
PYH1_k127_4619428_14	1123072.AUDH01000002_gene2321	3.29e-39	153.0	COG5553@1|root,COG5553@2|Bacteria,1RBE3@1224|Proteobacteria,2VG78@28211|Alphaproteobacteria,2JX4K@204441|Rhodospirillales	204441|Rhodospirillales	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4619428_2	1380394.JADL01000001_gene2539	1.472e-160	526.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,2TSGP@28211|Alphaproteobacteria,2JR05@204441|Rhodospirillales	204441|Rhodospirillales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
PYH1_k127_4619428_5	1121861.KB899922_gene3120	1.567e-118	402.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TSME@28211|Alphaproteobacteria,2JPWJ@204441|Rhodospirillales	204441|Rhodospirillales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
PYH1_k127_4619428_11	1323663.AROI01000034_gene3950	1.938e-62	224.0	COG0463@1|root,COG0463@2|Bacteria,1N635@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PYH1_k127_46356_1	1112274.KI911560_gene406	1.835e-68	236.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria,2KKSH@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
PYH1_k127_46356_0	1232410.KI421419_gene2503	1.129e-133	433.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,43SFJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
PYH1_k127_46356_2	622637.KE124774_gene1697	1.313e-32	128.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,P22_AR_N,PriCT_1,Prim-Pol
PYH1_k127_4652575_3	1123354.AUDR01000013_gene827	1.505e-54	195.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,1KRF9@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
PYH1_k127_4652575_4	62928.azo2893	1.9e-20	100.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,2KX0P@206389|Rhodocyclales	206389|Rhodocyclales	KL	Belongs to the transcriptional regulatory Fis family	-	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
PYH1_k127_4652575_0	667632.KB890167_gene1564	3.297e-230	726.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,1K3VV@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
PYH1_k127_4652575_1	1123487.KB892857_gene2455	3.488e-186	616.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,2KUEI@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
PYH1_k127_4652575_2	391038.Bphy_2066	3.88e-130	442.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,1K0ZV@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
PYH1_k127_4652575_5	1304883.KI912532_gene1328	1.717e-10	63.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,2KVAI@206389|Rhodocyclales	206389|Rhodocyclales	H	enzyme of heme biosynthesis	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N
PYH1_k127_4698165_0	1123354.AUDR01000016_gene1294	1.855e-182	585.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,1KRB4@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
PYH1_k127_4698165_1	395494.Galf_2535	1.838e-09	70.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria,44VQA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine kinase	algZ	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
PYH1_k127_4702947_3	266265.Bxe_A1449	3.899e-40	152.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,1K0C6@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
PYH1_k127_4702947_1	335283.Neut_0197	2.671e-76	261.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,3720E@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Ribosomal RNA adenine dimethylase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
PYH1_k127_4702947_0	640081.Dsui_0405	4.051e-121	402.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,2KUK1@206389|Rhodocyclales	206389|Rhodocyclales	MU	COG1538 Outer membrane protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
PYH1_k127_4702947_2	85643.Tmz1t_3456	3.099e-58	209.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,2KUT0@206389|Rhodocyclales	206389|Rhodocyclales	M	3-Deoxy-D-manno-octulosonic-acid transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
PYH1_k127_4704543_10	977880.RALTA_A2581	7.797e-19	94.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,1JZPH@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
PYH1_k127_4704543_6	62928.azo3467	5.213e-82	278.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,2KU9T@206389|Rhodocyclales	206389|Rhodocyclales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
PYH1_k127_4704543_1	640081.Dsui_0604	6.664e-193	619.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,2KVBG@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
PYH1_k127_4704543_0	640081.Dsui_0605	1.22e-202	638.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KU9J@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
PYH1_k127_4704543_3	1380394.JADL01000001_gene2359	6.861e-124	402.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,2JWA5@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_4704543_2	62928.azo3477	1.339e-140	469.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,2KV05@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the methyltransferase superfamily	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
PYH1_k127_4704543_5	76114.ebA3579	5.231e-88	297.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,2KVIE@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-2 type transporter	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
PYH1_k127_4704543_4	1485544.JQKP01000002_gene1427	4.665e-122	413.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,44VG9@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
PYH1_k127_4704543_7	757424.Hsero_4307	1.975e-60	217.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,4732H@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
PYH1_k127_4704543_9	1122604.JONR01000007_gene2801	3.933e-46	168.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1S8U3@1236|Gammaproteobacteria,1X7ZG@135614|Xanthomonadales	135614|Xanthomonadales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
PYH1_k127_4704543_8	522306.CAP2UW1_3572	8.771e-49	182.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,1KQT3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PYH1_k127_4741067_10	1121035.AUCH01000025_gene3303	1.068e-22	98.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,2KW5V@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
PYH1_k127_4741067_1	983917.RGE_44060	6.254e-147	471.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,1KJ50@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
PYH1_k127_4741067_6	159087.Daro_3881	6.857e-74	261.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,2KW73@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
PYH1_k127_4741067_0	323848.Nmul_A0568	0.0	1138.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,372B8@32003|Nitrosomonadales	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
PYH1_k127_4741067_3	85643.Tmz1t_3814	3.387e-108	355.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,2KUFM@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
PYH1_k127_4741067_9	62928.azo3602	4.527e-23	104.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria,2KXDS@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
PYH1_k127_4741067_2	323848.Nmul_A0565	4.63e-110	366.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,37292@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
PYH1_k127_4741067_7	522306.CAP2UW1_1113	3.15e-48	184.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria,1KQZ5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4741067_4	1163617.SCD_n00281	3.877e-100	346.0	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4741067_8	338969.Rfer_1290	3.353e-43	179.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,4ADW0@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
PYH1_k127_4741067_5	1123487.KB892834_gene3024	3.756e-98	332.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,2KUUC@206389|Rhodocyclales	206389|Rhodocyclales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
PYH1_k127_4741067_11	640081.Dsui_0860	0.0005763	44.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria,2KV4Q@206389|Rhodocyclales	206389|Rhodocyclales	S	import inner membrane translocase subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
PYH1_k127_4752798_4	1163617.SCD_n01273	8.205e-34	145.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria	28216|Betaproteobacteria	H	MoeA domain protein domain I and II	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
PYH1_k127_4752798_2	497321.C664_01875	3.495e-59	222.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,2KWDE@206389|Rhodocyclales	206389|Rhodocyclales	H	molybdopterin-guanine dinucleotide biosynthesis protein	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
PYH1_k127_4752798_1	1173020.Cha6605_4325	3.109e-64	228.0	COG0730@1|root,COG0730@2|Bacteria,1G72I@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH1_k127_4752798_0	748247.AZKH_0484	1.302e-124	409.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2VJQG@28216|Betaproteobacteria,2KUXA@206389|Rhodocyclales	206389|Rhodocyclales	H	Bacterial extracellular solute-binding protein	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
PYH1_k127_4752798_3	570967.JMLV01000007_gene910	2.754e-42	156.0	COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2TSCU@28211|Alphaproteobacteria,2JRVW@204441|Rhodospirillales	204441|Rhodospirillales	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PYH1_k127_4753806_3	335543.Sfum_3501	4.618e-62	221.0	COG2271@1|root,COG2271@2|Bacteria,1QXP5@1224|Proteobacteria,43C51@68525|delta/epsilon subdivisions,2X7FD@28221|Deltaproteobacteria,2MR8I@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_4753806_4	1380394.JADL01000021_gene1878	9.806e-52	185.0	COG0251@1|root,COG0251@2|Bacteria,1N7Z1@1224|Proteobacteria,2V8A2@28211|Alphaproteobacteria,2JXG1@204441|Rhodospirillales	204441|Rhodospirillales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
PYH1_k127_4753806_1	1038859.AXAU01000007_gene5808	1.324e-145	470.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_4753806_2	1528106.JRJE01000004_gene631	3.734e-133	430.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,2JQIB@204441|Rhodospirillales	204441|Rhodospirillales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
PYH1_k127_4753806_0	1288494.EBAPG3_7780	4.669e-171	544.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,371W0@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
PYH1_k127_4795450_5	1122604.JONR01000009_gene2309	2.201e-130	422.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
PYH1_k127_4795450_27	1120985.AUMI01000017_gene2583	4.635e-11	68.0	COG1366@1|root,COG1366@2|Bacteria,1VZCA@1239|Firmicutes,4H85Q@909932|Negativicutes	909932|Negativicutes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
PYH1_k127_4795450_16	1380394.JADL01000008_gene3609	7.081e-59	215.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2TZJ8@28211|Alphaproteobacteria,2JUBE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4795450_13	388051.AUFE01000005_gene1054	7.158e-63	226.0	COG2267@1|root,COG2267@2|Bacteria,1P7JV@1224|Proteobacteria,2VR0X@28216|Betaproteobacteria,1K7Z4@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_4795450_23	1218076.BAYB01000012_gene2643	3.42e-35	139.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,1K73W@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
PYH1_k127_4795450_22	62928.azo1599	5.997e-37	148.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,2KWJN@206389|Rhodocyclales	206389|Rhodocyclales	S	ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
PYH1_k127_4795450_21	159087.Daro_2195	1.127e-38	161.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,2VT2B@28216|Betaproteobacteria,2KWKJ@206389|Rhodocyclales	206389|Rhodocyclales	NU	pilus assembly protein PilZ	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
PYH1_k127_4795450_14	360910.BAV1765	7.372e-63	235.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,3T2FA@506|Alcaligenaceae	28216|Betaproteobacteria	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
PYH1_k127_4795450_11	257310.BB2637	6.597e-65	231.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,3T3YF@506|Alcaligenaceae	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
PYH1_k127_4795450_8	522306.CAP2UW1_2472	6.82e-117	385.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,1KPZ8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
PYH1_k127_4795450_17	305700.B447_10438	3.739e-57	209.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,2KVRU@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
PYH1_k127_4795450_29	279714.FuraDRAFT_2987	0.000202	55.0	2EPNT@1|root,33H9E@2|Bacteria,1NI6Z@1224|Proteobacteria,2WB54@28216|Betaproteobacteria,2KTH2@206351|Neisseriales	206351|Neisseriales	S	Domain of unknown function (DUF4936)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4936
PYH1_k127_4795450_18	1454004.AW11_01223	6.557e-54	198.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,2VQK6@28216|Betaproteobacteria,1KQTN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
PYH1_k127_4795450_20	1175306.GWL_20780	4.611e-45	168.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,474GP@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
PYH1_k127_4795450_1	111781.Lepto7376_0265	2.029e-271	852.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1G0Q0@1117|Cyanobacteria,1H8S9@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
PYH1_k127_4795450_7	1163617.SCD_n00520	7.441e-120	395.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2VI2X@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
PYH1_k127_4795450_12	1288494.EBAPG3_12840	2.936e-64	233.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,3730C@32003|Nitrosomonadales	28216|Betaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
PYH1_k127_4795450_19	587753.EY04_25095	1.596e-45	168.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
PYH1_k127_4795450_24	398578.Daci_4021	7.85e-28	121.0	COG3103@1|root,COG3103@2|Bacteria,1QVCP@1224|Proteobacteria,2WC3N@28216|Betaproteobacteria,4AIT6@80864|Comamonadaceae	28216|Betaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4795450_28	159450.NH14_14110	1.922e-05	55.0	2DP14@1|root,3303I@2|Bacteria,1N7JW@1224|Proteobacteria,2VW7N@28216|Betaproteobacteria,1KA2M@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4795450_9	614083.AWQR01000008_gene471	8.988e-83	282.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2VNMI@28216|Betaproteobacteria,4AFB5@80864|Comamonadaceae	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
PYH1_k127_4795450_4	439235.Dalk_0841	8.006e-149	485.0	COG0859@1|root,COG0859@2|Bacteria,1PQIG@1224|Proteobacteria,42MUM@68525|delta/epsilon subdivisions,2WPZT@28221|Deltaproteobacteria,2MN6W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
PYH1_k127_4795450_6	891968.Anamo_1881	3.559e-121	419.0	COG0463@1|root,COG1807@1|root,COG2246@1|root,COG0463@2|Bacteria,COG1807@2|Bacteria,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	MA20_09515	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA,PMT_2
PYH1_k127_4795450_15	1121403.AUCV01000010_gene1406	2.233e-60	220.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,42WVD@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
PYH1_k127_4795450_10	399739.Pmen_0366	3.049e-80	303.0	COG0671@1|root,COG0671@2|Bacteria,1MW7A@1224|Proteobacteria,1SDGJ@1236|Gammaproteobacteria,1YG18@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	PAP2 superfamily	yeiU	-	2.7.4.29	ko:K19803	-	-	R11186	RC00002	ko00000,ko01000,ko01005	-	-	-	PAP2
PYH1_k127_4795450_2	622637.KE124774_gene1454	1.482e-268	840.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	arylsulfatase A	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
PYH1_k127_4795450_25	1123392.AQWL01000001_gene1542	5.683e-20	93.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,1KT2S@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
PYH1_k127_4795450_0	305700.B447_00470	6.078e-276	854.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,2KVB1@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
PYH1_k127_4795450_3	580332.Slit_1465	1.619e-237	742.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,44VBE@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
PYH1_k127_4795450_26	1454004.AW11_01180	2.824e-14	85.0	2BCK1@1|root,32662@2|Bacteria,1RHH4@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
PYH1_k127_4824728_4	1223521.BBJX01000002_gene2865	1.88e-100	344.0	COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,2VKFW@28216|Betaproteobacteria,4AH9U@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
PYH1_k127_4824728_9	596153.Alide_3613	1.052e-23	117.0	2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria,4AGT7@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4824728_3	522306.CAP2UW1_1327	6.29e-116	396.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2VNFS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,Fer4_7,FlpD
PYH1_k127_4824728_8	522306.CAP2UW1_1325	2.311e-34	145.0	2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4824728_1	522306.CAP2UW1_1324	3.05e-241	773.0	COG0543@1|root,COG1018@1|root,COG1290@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,COG1290@2|Bacteria,1MV72@1224|Proteobacteria,2VI6M@28216|Betaproteobacteria,1KR75@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,FAD_binding_6,Fer2,NAD_binding_1
PYH1_k127_4824728_7	1437824.BN940_02356	7.857e-69	242.0	COG1999@1|root,COG1999@2|Bacteria,1N6WC@1224|Proteobacteria,2VMIP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
PYH1_k127_4824728_5	1223521.BBJX01000002_gene2861	2.241e-96	323.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VM89@28216|Betaproteobacteria,4AHA1@80864|Comamonadaceae	28216|Betaproteobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
PYH1_k127_4824728_0	1223521.BBJX01000002_gene2860	1.785e-245	769.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2VJ1N@28216|Betaproteobacteria,4AHFT@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c oxidase, subunit I	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
PYH1_k127_4824728_6	1437824.BN940_02346	4.411e-80	271.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2VNRT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome c oxidase (Subunit II)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
PYH1_k127_4824728_10	1244869.H261_01557	4.585e-13	70.0	2ERCE@1|root,33IY3@2|Bacteria,1NNN9@1224|Proteobacteria,2UXY5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4824728_2	261292.Nit79A3_2374	1.581e-117	387.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2WAY9@28216|Betaproteobacteria,371NX@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
PYH1_k127_4837051_16	1123393.KB891318_gene2169	3.85e-30	121.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,1KTCQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
PYH1_k127_4837051_5	640081.Dsui_1316	1.348e-85	287.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,2KV5C@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
PYH1_k127_4837051_1	335283.Neut_0616	1.637e-287	893.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,371U3@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
PYH1_k127_4837051_15	43759.JNWK01000015_gene25	4.243e-32	128.0	COG4290@1|root,COG4290@2|Bacteria,2IHPV@201174|Actinobacteria	201174|Actinobacteria	F	Ribonuclease	-	-	3.1.27.3	ko:K01167	-	-	-	-	ko00000,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
PYH1_k127_4837051_17	305700.B447_16582	2.757e-18	89.0	COG2732@1|root,COG2732@2|Bacteria,1NB8S@1224|Proteobacteria,2WE8N@28216|Betaproteobacteria,2KX6I@206389|Rhodocyclales	206389|Rhodocyclales	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
PYH1_k127_4837051_11	1038869.AXAN01000013_gene6335	1.823e-46	184.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,1K6ZD@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
PYH1_k127_4837051_12	204773.HEAR2693	1.434e-42	164.0	COG2867@1|root,COG2867@2|Bacteria,1QUZA@1224|Proteobacteria,2VUHS@28216|Betaproteobacteria,4750S@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
PYH1_k127_4837051_3	522306.CAP2UW1_2397	1.835e-109	377.0	28H91@1|root,2Z7KU@2|Bacteria,1R4NB@1224|Proteobacteria,2VS45@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4837051_4	1348657.M622_15640	1.614e-97	329.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,2KV21@206389|Rhodocyclales	206389|Rhodocyclales	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
PYH1_k127_4837051_2	1454004.AW11_00136	1.175e-125	417.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,1KQMM@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
PYH1_k127_4837051_9	926550.CLDAP_36760	6.15e-51	193.0	COG2030@1|root,COG2030@2|Bacteria,2G8WQ@200795|Chloroflexi	200795|Chloroflexi	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
PYH1_k127_4837051_10	1158292.JPOE01000005_gene1018	1.487e-48	185.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,2VTGX@28216|Betaproteobacteria,1KKWK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
PYH1_k127_4837051_13	267608.RSc1773	5.106e-35	143.0	COG0824@1|root,COG0824@2|Bacteria,1N4X2@1224|Proteobacteria,2WES2@28216|Betaproteobacteria,1K7JY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
PYH1_k127_4837051_8	318996.AXAZ01000008_gene4200	4.308e-53	192.0	COG3193@1|root,COG3193@2|Bacteria,1REF5@1224|Proteobacteria,2U5M2@28211|Alphaproteobacteria,3JYF2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
PYH1_k127_4837051_14	1286093.C266_23718	7.857e-35	139.0	2CDFS@1|root,32RXQ@2|Bacteria,1RIZ3@1224|Proteobacteria,2WFT8@28216|Betaproteobacteria,1K3W9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2946)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2944
PYH1_k127_4837051_7	580332.Slit_0762	3.812e-64	222.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2VR2H@28216|Betaproteobacteria,44VUV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
PYH1_k127_4837051_6	85643.Tmz1t_3342	3.397e-73	257.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2VQ63@28216|Betaproteobacteria,2KVWF@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
PYH1_k127_4837051_0	1095769.CAHF01000004_gene2744	0.0	1176.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,4734N@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
PYH1_k127_4837051_18	522306.CAP2UW1_3495	4.974e-18	84.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,1KPWG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
PYH1_k127_4903741_1	62928.azo3501	2.94e-109	363.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VH2U@28216|Betaproteobacteria,2KUEE@206389|Rhodocyclales	206389|Rhodocyclales	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
PYH1_k127_4903741_2	748247.AZKH_4583	2.113e-61	227.0	COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,2VRF6@28216|Betaproteobacteria,2KV9Q@206389|Rhodocyclales	206389|Rhodocyclales	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
PYH1_k127_4903741_5	62928.azo3503	1.47e-43	165.0	COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,2VMRF@28216|Betaproteobacteria,2KWN7@206389|Rhodocyclales	206389|Rhodocyclales	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
PYH1_k127_4903741_0	1165096.ARWF01000001_gene1500	2.336e-313	970.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2VJYX@28216|Betaproteobacteria,2KMBT@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
PYH1_k127_4903741_7	1454202.PPBDW_120494___1	2.105e-38	149.0	COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,1S8UP@1236|Gammaproteobacteria,1XY5U@135623|Vibrionales	135623|Vibrionales	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
PYH1_k127_4903741_4	265072.Mfla_1769	1.337e-48	176.0	COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,2VSES@28216|Betaproteobacteria,2KMXX@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
PYH1_k127_4903741_6	1502851.FG93_01828	2.895e-39	162.0	COG3971@1|root,COG3971@2|Bacteria,1RA35@1224|Proteobacteria,2VFYX@28211|Alphaproteobacteria,3K4SI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
PYH1_k127_4903741_3	1121035.AUCH01000023_gene3418	6.833e-58	207.0	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2VHXH@28216|Betaproteobacteria,2KVE9@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
PYH1_k127_4963502_37	1286631.X805_21070	5.754e-06	49.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,1KKB4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
PYH1_k127_4963502_1	1163617.SCD_n02021	1.5e-238	757.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
PYH1_k127_4963502_17	543913.D521_1163	8.108e-77	262.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2VRTS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
PYH1_k127_4963502_10	1123073.KB899244_gene250	1.172e-116	387.0	COG0697@1|root,COG0697@2|Bacteria,1N3FA@1224|Proteobacteria,1RYMI@1236|Gammaproteobacteria,1X5QQ@135614|Xanthomonadales	135614|Xanthomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_4963502_26	1121035.AUCH01000016_gene2171	3.077e-46	171.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,2KWQ3@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
PYH1_k127_4963502_2	667632.KB890198_gene1313	3.331e-232	724.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,2VHVD@28216|Betaproteobacteria,1K0EF@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Isocitrate dehydrogenase	icd	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
PYH1_k127_4963502_30	640081.Dsui_0007	1.552e-35	137.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,2KWX9@206389|Rhodocyclales	206389|Rhodocyclales	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
PYH1_k127_4963502_27	323848.Nmul_A2247	1.589e-44	163.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2VSCU@28216|Betaproteobacteria,373HT@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
PYH1_k127_4963502_0	265072.Mfla_0508	0.0	1180.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KKYH@206350|Nitrosomonadales	206350|Nitrosomonadales	O	TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
PYH1_k127_4963502_34	1000565.METUNv1_02965	1.477e-24	107.0	COG2863@1|root,COG2863@2|Bacteria,1NGJ1@1224|Proteobacteria,2VVR2@28216|Betaproteobacteria,2KX1J@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
PYH1_k127_4963502_5	1100721.ALKO01000017_gene1688	5.287e-160	515.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,4AA1P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	soxF	-	1.8.2.1,1.8.5.4	ko:K05301,ko:K17218	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528,R10152	RC00168,RC03155	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
PYH1_k127_4963502_21	360910.BAV1402	3.923e-64	228.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,3T3SG@506|Alcaligenaceae	28216|Betaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
PYH1_k127_4963502_6	522306.CAP2UW1_2549	1.952e-145	475.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,1KPTU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
PYH1_k127_4963502_16	1454004.AW11_03700	1.312e-83	283.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,1KQM0@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
PYH1_k127_4963502_31	556268.OFAG_02312	1.105e-30	122.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,474U7@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
PYH1_k127_4963502_35	640081.Dsui_1534	1.369e-20	95.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,2KXDQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
PYH1_k127_4963502_4	1157708.KB907462_gene897	3.297e-178	565.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,4AB2U@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
PYH1_k127_4963502_9	76114.ebA645	3.66e-118	393.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria,2KU8B@206389|Rhodocyclales	206389|Rhodocyclales	M	mechanosensitive	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM,MscS_porin
PYH1_k127_4963502_29	265072.Mfla_0789	4.733e-43	168.0	2CDK7@1|root,2ZAP2@2|Bacteria,1N018@1224|Proteobacteria,2VH8P@28216|Betaproteobacteria,2KMTF@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_4963502_11	543728.Vapar_5729	1.177e-105	347.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2VJSY@28216|Betaproteobacteria,4AC5T@80864|Comamonadaceae	28216|Betaproteobacteria	P	Membrane protein TerC	terC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,TerC
PYH1_k127_4963502_8	522306.CAP2UW1_2807	2.665e-125	417.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,1KPVB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
PYH1_k127_4963502_32	292415.Tbd_2665	1.259e-29	136.0	COG3170@1|root,COG3170@2|Bacteria,1N3SZ@1224|Proteobacteria,2VU3V@28216|Betaproteobacteria,1KRVW@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
PYH1_k127_4963502_33	1236959.BAMT01000006_gene388	2.983e-28	130.0	COG3147@1|root,COG3147@2|Bacteria,1RCIU@1224|Proteobacteria,2WHQJ@28216|Betaproteobacteria,2KMRI@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
PYH1_k127_4963502_18	757424.Hsero_1177	1.269e-76	261.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,473PS@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
PYH1_k127_4963502_22	748247.AZKH_4168	7.935e-59	222.0	COG3735@1|root,COG3735@2|Bacteria,1RBFT@1224|Proteobacteria,2VTX0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
PYH1_k127_4963502_23	32057.KB217478_gene1288	5.38e-51	203.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria,1HMWG@1161|Nostocales	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
PYH1_k127_4963502_3	640081.Dsui_0926	4.729e-209	658.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,2KUIN@206389|Rhodocyclales	206389|Rhodocyclales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
PYH1_k127_4963502_20	556269.ACDQ01000017_gene818	4.979e-65	229.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,474AV@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
PYH1_k127_4963502_13	381666.H16_A2714	2.08e-101	340.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,1K0N7@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
PYH1_k127_4963502_25	1123368.AUIS01000009_gene2457	1.733e-47	181.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S8VM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA3	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PYH1_k127_4963502_14	396588.Tgr7_1031	5.792e-101	340.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1WXFV@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
PYH1_k127_4963502_19	640081.Dsui_2861	1.273e-69	250.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VIII@28216|Betaproteobacteria,2KWBA@206389|Rhodocyclales	206389|Rhodocyclales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_4963502_7	1380394.JADL01000023_gene34	1.805e-130	428.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2JS9F@204441|Rhodospirillales	204441|Rhodospirillales	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
PYH1_k127_4963502_24	62928.azo0789	1.548e-50	186.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,2KW96@206389|Rhodocyclales	206389|Rhodocyclales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
PYH1_k127_4963502_15	1144342.PMI40_02395	6.925e-89	313.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2VHTD@28216|Betaproteobacteria,472Z6@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Probable molybdopterin binding domain	yfaY	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
PYH1_k127_4963502_12	224911.27354751	4.283e-104	358.0	COG0491@1|root,COG0491@2|Bacteria,1PPPW@1224|Proteobacteria,2U30I@28211|Alphaproteobacteria,3JX0I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PYH1_k127_4963502_28	580332.Slit_1234	3.496e-44	172.0	COG2981@1|root,COG2981@2|Bacteria,1Q181@1224|Proteobacteria,2VN29@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
PYH1_k127_4963502_36	1348657.M622_11155	1.935e-14	74.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,2KUB1@206389|Rhodocyclales	206389|Rhodocyclales	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
PYH1_k127_5133777_0	1095769.CAHF01000009_gene1397	3.256e-144	463.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,4730X@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
PYH1_k127_5133777_3	1163617.SCD_n00989	1.326e-98	348.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	abc transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
PYH1_k127_5133777_5	314285.KT71_01925	1.044e-67	235.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1J998@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	SelR domain	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR,TAT_signal
PYH1_k127_5133777_1	1205680.CAKO01000038_gene1586	6.594e-135	439.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JRXA@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_5133777_6	1205680.CAKO01000040_gene808	5.937e-63	222.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_5133777_4	1234364.AMSF01000056_gene1125	8.014e-87	294.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,1X3A0@135614|Xanthomonadales	135614|Xanthomonadales	S	dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
PYH1_k127_5133777_2	1123023.JIAI01000017_gene3575	1.694e-100	331.0	COG1028@1|root,COG1028@2|Bacteria,2GKT2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH1_k127_5166251_0	557598.LHK_01303	2.865e-168	536.0	COG0074@1|root,COG0074@2|Bacteria,1MX67@1224|Proteobacteria,2VPK5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
PYH1_k127_5166251_1	196367.JNFG01000203_gene378	1.023e-104	366.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,2VM5W@28216|Betaproteobacteria,1K4E6@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PYH1_k127_5175727_2	637389.Acaty_c2263	2.398e-26	108.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria,2NCAJ@225057|Acidithiobacillales	225057|Acidithiobacillales	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PYH1_k127_5175727_1	637389.Acaty_c2264	7.857e-35	140.0	290SD@1|root,2ZNEH@2|Bacteria,1P6XW@1224|Proteobacteria,1STK8@1236|Gammaproteobacteria,2NC0Z@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_5175727_0	358220.C380_11990	9.842e-112	374.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2VIUQ@28216|Betaproteobacteria,4A9JA@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM multi antimicrobial extrusion protein MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PYH1_k127_518635_0	640081.Dsui_2814	4.809e-223	701.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,2KUJF@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
PYH1_k127_518635_2	1288494.EBAPG3_3540	3.344e-55	200.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
PYH1_k127_518635_1	1288494.EBAPG3_3540	2.456e-55	205.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
PYH1_k127_518635_3	795666.MW7_1754	9.283e-46	169.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,1K1HX@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
PYH1_k127_5239123_1	1123368.AUIS01000006_gene688	4.531e-80	278.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,2NCPG@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
PYH1_k127_5239123_2	1121035.AUCH01000021_gene2713	8.463e-32	129.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,2KWPI@206389|Rhodocyclales	206389|Rhodocyclales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
PYH1_k127_5239123_0	159450.NH14_10585	7.836e-299	926.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,1K43X@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
PYH1_k127_5240148_3	1380394.JADL01000003_gene5040	3.414e-60	219.0	COG1024@1|root,COG1024@2|Bacteria,1PU1Q@1224|Proteobacteria,2TSW6@28211|Alphaproteobacteria,2JS2P@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_5240148_1	1000565.METUNv1_03710	3.318e-134	435.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
PYH1_k127_5240148_0	1123073.KB899242_gene1461	3.523e-321	990.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1XA61@135614|Xanthomonadales	135614|Xanthomonadales	CE	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
PYH1_k127_5240148_2	543728.Vapar_5478	1.016e-74	274.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria,4A9VY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
PYH1_k127_5270051_3	580332.Slit_2048	1.197e-102	339.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VMQU@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
PYH1_k127_5270051_9	1278307.KB906999_gene16	7.54e-10	71.0	COG3103@1|root,COG3103@2|Bacteria,1N6AX@1224|Proteobacteria,1SGVD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
PYH1_k127_5270051_5	580332.Slit_2046	7.193e-88	306.0	COG4784@1|root,COG4784@2|Bacteria,1QXTD@1224|Proteobacteria,2WHJ6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
PYH1_k127_5270051_7	1163617.SCD_n01782	1.789e-76	280.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
PYH1_k127_5270051_0	1288494.EBAPG3_11650	9.017e-193	613.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VNWB@28216|Betaproteobacteria,372JZ@32003|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Aminotransferase, class V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
PYH1_k127_5270051_1	1336243.JAEA01000010_gene3537	2.801e-191	612.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TS3K@28211|Alphaproteobacteria,1JRKY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_5270051_4	1131553.JIBI01000004_gene396	2.269e-90	302.0	28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,2VZB8@28216|Betaproteobacteria,372HT@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3750
PYH1_k127_5270051_2	1211114.ALIP01000004_gene1187	3.95e-119	402.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1X416@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
PYH1_k127_5270051_6	1123354.AUDR01000013_gene591	3.625e-78	273.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,1KRK0@119069|Hydrogenophilales	119069|Hydrogenophilales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
PYH1_k127_5270051_8	748280.NH8B_0409	8.603e-29	117.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,2KPHC@206351|Neisseriales	206351|Neisseriales	S	cyclopropane-fatty-acyl-phospholipid synthase K00574	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
PYH1_k127_5299982_5	640081.Dsui_1946	1.294e-79	269.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,2KU7Z@206389|Rhodocyclales	206389|Rhodocyclales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16
PYH1_k127_5299982_0	1121035.AUCH01000001_gene2089	2.31e-199	638.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,2KUMY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
PYH1_k127_5299982_3	1454004.AW11_01590	4.993e-111	388.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria,1KQ96@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272,ko:K21344	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
PYH1_k127_5299982_2	522306.CAP2UW1_2894	2.051e-128	420.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,1KQBQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
PYH1_k127_5299982_1	640081.Dsui_1954	1.967e-147	488.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,2KV1N@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH1_k127_5299982_4	1485544.JQKP01000013_gene1837	6.559e-105	349.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,44V01@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
PYH1_k127_5299982_6	1437824.BN940_08771	3.727e-15	79.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,3T29H@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
PYH1_k127_5306688_1	1123393.KB891330_gene842	2.25e-179	567.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,1KSIC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH1_k127_5306688_0	261292.Nit79A3_0883	5.502e-204	644.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,371YV@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
PYH1_k127_5330393_3	1396141.BATP01000038_gene1225	1.139e-20	103.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46VP8@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
PYH1_k127_5330393_2	1007105.PT7_0670	4.688e-51	187.0	COG2030@1|root,COG2030@2|Bacteria,1RH7U@1224|Proteobacteria,2W98C@28216|Betaproteobacteria,3T7IZ@506|Alcaligenaceae	28216|Betaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
PYH1_k127_5330393_1	1231391.AMZF01000014_gene2317	1.435e-89	305.0	COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria	1224|Proteobacteria	S	TRAP transporter, solute receptor (TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
PYH1_k127_5330393_0	1231391.AMZF01000014_gene2316	3.128e-214	699.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,3T1N0@506|Alcaligenaceae	28216|Betaproteobacteria	S	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_5338238_6	159087.Daro_3866	3.683e-13	70.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,2KUXG@206389|Rhodocyclales	206389|Rhodocyclales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
PYH1_k127_5338238_0	159087.Daro_0033	1.043e-212	680.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,2KVAV@206389|Rhodocyclales	206389|Rhodocyclales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
PYH1_k127_5338238_1	1000565.METUNv1_03481	5.796e-169	536.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,2KV0I@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
PYH1_k127_5338238_2	358220.C380_11520	4.691e-67	231.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,4AE5E@80864|Comamonadaceae	28216|Betaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
PYH1_k127_5338238_4	1266925.JHVX01000003_gene511	8.343e-31	124.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VUY2@28216|Betaproteobacteria,373CS@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
PYH1_k127_5338238_3	62928.azo3520	3.536e-54	193.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,2KU8W@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
PYH1_k127_5338249_1	3988.XP_002534562.1	2.515e-40	167.0	COG0304@1|root,KOG1394@2759|Eukaryota,37JJ8@33090|Viridiplantae,3GEQX@35493|Streptophyta,4JJVQ@91835|fabids	35493|Streptophyta	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PYH1_k127_5338249_2	411473.RUMCAL_02187	1.915e-09	61.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3WKU1@541000|Ruminococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
PYH1_k127_5338249_0	1121035.AUCH01000009_gene888	1.106e-143	464.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,2KV1D@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
PYH1_k127_5360686_3	1121033.AUCF01000003_gene3326	1.077e-13	73.0	COG4671@1|root,COG4671@2|Bacteria,1NE6T@1224|Proteobacteria,2U08G@28211|Alphaproteobacteria,2JQPD@204441|Rhodospirillales	204441|Rhodospirillales	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
PYH1_k127_5360686_1	1380394.JADL01000001_gene2040	6.012e-53	199.0	COG0726@1|root,COG0726@2|Bacteria,1R5QW@1224|Proteobacteria,2TTV0@28211|Alphaproteobacteria,2JS3M@204441|Rhodospirillales	204441|Rhodospirillales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_5360686_2	1380394.JADL01000001_gene2041	1.483e-34	139.0	2E8MG@1|root,332YX@2|Bacteria,1NA87@1224|Proteobacteria,2UGW0@28211|Alphaproteobacteria,2JU7Z@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_5360686_0	1380394.JADL01000001_gene2042	3.253e-95	322.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2JPA1@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_5380572_0	1134912.AJTV01000038_gene3330	0.0	1813.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,36Y2W@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.321	ko:K13688,ko:K18786	-	-	R10832	RC00397	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
PYH1_k127_5489885_4	557598.LHK_03052	2.646e-16	80.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,2KR2D@206351|Neisseriales	206351|Neisseriales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
PYH1_k127_5489885_0	196367.JNFG01000025_gene8289	2.597e-193	613.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,1K1ZW@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
PYH1_k127_5489885_1	1304883.KI912532_gene1577	6.613e-148	478.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,2KV6H@206389|Rhodocyclales	206389|Rhodocyclales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
PYH1_k127_5489885_2	159087.Daro_3492	4.767e-130	421.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,2KU6A@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
PYH1_k127_5489885_5	267608.RSc2836	1.29e-09	70.0	COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,2VWI9@28216|Betaproteobacteria,1K86K@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
PYH1_k127_5489885_3	1288494.EBAPG3_28070	3.789e-93	317.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,371UP@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
PYH1_k127_5497238_4	62928.azo3298	8.55e-13	72.0	2A8MT@1|root,30XQ7@2|Bacteria,1PJJK@1224|Proteobacteria,2WB51@28216|Betaproteobacteria,2KXIZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2909)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2909
PYH1_k127_5497238_2	62928.azo3299	1.176e-114	376.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,2KVIW@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
PYH1_k127_5497238_6	196367.JNFG01000206_gene151	0.0008198	50.0	2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria,2VXNC@28216|Betaproteobacteria,1KABT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2970)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2970
PYH1_k127_5497238_3	1123367.C666_13305	8.407e-70	242.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2VHRQ@28216|Betaproteobacteria,2KWGM@206389|Rhodocyclales	206389|Rhodocyclales	O	oxidase assembly	-	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
PYH1_k127_5497238_0	1000565.METUNv1_02089	1.756e-287	889.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,2KUWI@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
PYH1_k127_5497238_1	62928.azo3304	1.621e-153	494.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,2KV6W@206389|Rhodocyclales	206389|Rhodocyclales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
PYH1_k127_5497238_5	159087.Daro_0619	3.358e-09	58.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,2KUJH@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
PYH1_k127_5516986_3	622637.KE124774_gene1697	2.069e-49	181.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,P22_AR_N,PriCT_1,Prim-Pol
PYH1_k127_5516986_0	1095769.CAHF01000006_gene1873	8.655e-107	358.0	COG3243@1|root,COG3243@2|Bacteria,1Q6YK@1224|Proteobacteria,2VTR0@28216|Betaproteobacteria,476NS@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
PYH1_k127_5516986_1	1123392.AQWL01000003_gene277	5.99e-66	232.0	COG0778@1|root,COG0778@2|Bacteria,1Q0ZY@1224|Proteobacteria,2WAFT@28216|Betaproteobacteria,1KSUE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
PYH1_k127_5516986_2	864051.BurJ1DRAFT_3311	4.661e-64	225.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria,1KKQ5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
PYH1_k127_5526542_13	614083.AWQR01000001_gene3114	1.893e-74	254.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,4ACGH@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_5526542_12	391587.KAOT1_18412	8.573e-77	270.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K20306	-	-	-	-	ko00000,ko04131	-	-	-	Lipase_GDSL,Lipase_GDSL_2
PYH1_k127_5526542_18	395495.Lcho_1836	5.238e-34	149.0	COG2050@1|root,COG2050@2|Bacteria,1N5HF@1224|Proteobacteria,2VQ8W@28216|Betaproteobacteria,1KM7Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH1_k127_5526542_6	1038867.AXAY01000008_gene455	4.338e-153	517.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,3JSPS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	MA20_22980	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_5526542_8	1479237.JMLY01000001_gene3127	6.728e-130	449.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,465BW@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Acetyl propionyl-CoA carboxylase, alpha subunit	mccA	-	6.4.1.4,6.4.1.5	ko:K01968,ko:K13777	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R03494,R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
PYH1_k127_5526542_3	402626.Rpic_0107	3.492e-188	593.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VJ5I@28216|Betaproteobacteria,1K6EI@119060|Burkholderiaceae	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_5526542_1	1123367.C666_11230	5.423e-233	746.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,2KVX8@206389|Rhodocyclales	28216|Betaproteobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	6.4.1.4,6.4.1.5	ko:K01969,ko:K13778	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R03494,R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
PYH1_k127_5526542_10	264198.Reut_B5205	5.802e-110	375.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2VK16@28216|Betaproteobacteria,1K64U@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
PYH1_k127_5526542_20	768671.ThimaDRAFT_3580	4.407e-14	78.0	2E35M@1|root,32Y5I@2|Bacteria,1NFVT@1224|Proteobacteria,1SI61@1236|Gammaproteobacteria,1WZPI@135613|Chromatiales	135613|Chromatiales	K	PFAM CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
PYH1_k127_5526542_17	768671.ThimaDRAFT_3581	3.898e-35	140.0	COG2337@1|root,COG2337@2|Bacteria,1RJ3H@1224|Proteobacteria,1SF5N@1236|Gammaproteobacteria,1X10V@135613|Chromatiales	135613|Chromatiales	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
PYH1_k127_5526542_4	272560.BPSL0061	1.192e-179	569.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VH9Y@28216|Betaproteobacteria,1K0HZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_5526542_2	296591.Bpro_3015	1.61e-197	621.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VHMS@28216|Betaproteobacteria,4ABPG@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH1_k127_5526542_0	1095769.CAHF01000011_gene2128	1.003e-283	907.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,473M2@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	fadB2	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
PYH1_k127_5526542_5	706587.Desti_1123	2.198e-159	534.0	COG2855@1|root,COG2855@2|Bacteria,1MVPE@1224|Proteobacteria,42NT6@68525|delta/epsilon subdivisions,2WJ9R@28221|Deltaproteobacteria,2MR46@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
PYH1_k127_5526542_9	1095769.CAHF01000005_gene1491	2.344e-127	443.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2VH48@28216|Betaproteobacteria,472G1@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	2-nitropropane dioxygenase	nppD	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
PYH1_k127_5526542_14	1031711.RSPO_c03139	1.549e-72	267.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,1K3TY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
PYH1_k127_5526542_16	1439940.BAY1663_03015	1.082e-38	153.0	COG2197@1|root,COG2197@2|Bacteria,1RGN8@1224|Proteobacteria	1224|Proteobacteria	K	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH1_k127_5526542_7	314278.NB231_05946	7.091e-147	484.0	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,1T1HR@1236|Gammaproteobacteria,1X2NS@135613|Chromatiales	135613|Chromatiales	V	Type I secretion system	-	-	-	ko:K16299	ko02010,map02010	M00571	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.110.10	-	-	ABC_membrane,ABC_tran
PYH1_k127_5526542_11	292.DM42_3784	1.21e-101	348.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VIAA@28216|Betaproteobacteria,1K8Z6@119060|Burkholderiaceae	28216|Betaproteobacteria	M	type I secretion membrane fusion	-	-	-	ko:K02022,ko:K12537	-	M00328	-	-	ko00000,ko00002,ko02000,ko02044	8.A.1	-	-	HlyD,HlyD_3
PYH1_k127_5526542_15	1244869.H261_01462	1.294e-46	182.0	COG0265@1|root,COG0790@1|root,COG0265@2|Bacteria,COG0790@2|Bacteria,1MV63@1224|Proteobacteria,2TS54@28211|Alphaproteobacteria,2JSRF@204441|Rhodospirillales	204441|Rhodospirillales	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sel1,Trypsin_2
PYH1_k127_5526542_19	472759.Nhal_2234	9.457e-31	127.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1X2AD@135613|Chromatiales	135613|Chromatiales	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_3_3,Peptidase_S8
PYH1_k127_5546686_2	76114.ebA727	9.627e-76	268.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,2KY7V@206389|Rhodocyclales	28216|Betaproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.25,6.2.1.27,6.2.1.37	ko:K04110,ko:K20458	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01300,R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding
PYH1_k127_5546686_1	1179778.PMM47T1_16895	1.545e-82	280.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1RN6Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
PYH1_k127_5546686_3	1121033.AUCF01000005_gene5341	5.817e-70	262.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,2JRTT@204441|Rhodospirillales	204441|Rhodospirillales	O	maleylacetoacetate isomerase	maiA	-	5.2.1.4	ko:K01801	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	GST_C_2,GST_C_3,GST_N,GST_N_3
PYH1_k127_5546686_6	1122915.AUGY01000118_gene6534	2.034e-50	190.0	COG3384@1|root,COG3384@2|Bacteria,1TVJK@1239|Firmicutes,4HDXX@91061|Bacilli,273V0@186822|Paenibacillaceae	91061|Bacilli	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.15	ko:K00455	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R03303	RC00643	ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
PYH1_k127_5546686_7	1144319.PMI16_04564	4.889e-21	98.0	COG0824@1|root,COG0824@2|Bacteria,1RG6B@1224|Proteobacteria,2VTAU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	-Thioesterase	-	-	3.1.2.23	ko:K01075	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT,4HBT_2
PYH1_k127_5546686_0	1232410.KI421426_gene1390	5.046e-139	454.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,42RJK@68525|delta/epsilon subdivisions,2WNEM@28221|Deltaproteobacteria,43UWP@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_5546686_4	497321.C664_11865	3.366e-61	213.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VTFS@28216|Betaproteobacteria,2KWUC@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
PYH1_k127_5546686_5	323848.Nmul_A0045	2.806e-53	192.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,372NK@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
PYH1_k127_5565043_1	296591.Bpro_1124	1.837e-51	191.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,4AASK@80864|Comamonadaceae	28216|Betaproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
PYH1_k127_5565043_2	365044.Pnap_4550	1.349e-29	119.0	COG5569@1|root,COG5569@2|Bacteria,1N8CJ@1224|Proteobacteria,2VVSU@28216|Betaproteobacteria,4AFJQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Copper binding periplasmic protein CusF	cusF	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
PYH1_k127_5565043_0	1346791.M529_19815	2.352e-203	647.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2JZXX@204457|Sphingomonadales	204457|Sphingomonadales	Q	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
PYH1_k127_5567211_1	292415.Tbd_2635	2.093e-47	173.0	COG0494@1|root,COG0494@2|Bacteria,1MYSK@1224|Proteobacteria,2W3WC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PYH1_k127_5567211_0	398767.Glov_3052	3.841e-81	284.0	COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2WNME@28221|Deltaproteobacteria,43TKF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PYH1_k127_5598747_0	1007105.PT7_2623	9.124e-232	726.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,3T6UJ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
PYH1_k127_5598747_1	365046.Rta_33920	1.269e-149	478.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VH6G@28216|Betaproteobacteria,4ABRZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
PYH1_k127_5598747_5	204773.HEAR3332	6.2e-95	323.0	COG1838@1|root,COG1838@2|Bacteria,1MVNG@1224|Proteobacteria,2VMDH@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Fumarate	-	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
PYH1_k127_5598747_6	1454004.AW11_03245	2.655e-51	188.0	2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,2WGJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
PYH1_k127_5598747_2	713586.KB900536_gene706	7.389e-135	451.0	COG1951@1|root,COG1951@2|Bacteria,1MW8J@1224|Proteobacteria,1RPUD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Tartrate	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
PYH1_k127_5598747_4	795666.MW7_2007	3.505e-98	335.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VKMJ@28216|Betaproteobacteria,1K0WK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_5598747_7	1380394.JADL01000014_gene197	1.161e-34	141.0	COG2009@1|root,COG2009@2|Bacteria,1N8VA@1224|Proteobacteria,2UAYI@28211|Alphaproteobacteria,2JXUG@204441|Rhodospirillales	204441|Rhodospirillales	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sdh_cyt
PYH1_k127_5598747_3	795666.MW7_3403	2.54e-112	368.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VJ4K@28216|Betaproteobacteria,1K70D@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
PYH1_k127_5602311_8	1122604.JONR01000006_gene2513	9.731e-38	146.0	COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
PYH1_k127_5602311_4	641524.ADICYQ_5472	1.101e-123	411.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
PYH1_k127_5602311_5	398767.Glov_0364	5.198e-110	377.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,42MXP@68525|delta/epsilon subdivisions,2WMI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
PYH1_k127_5602311_6	118166.JH976537_gene1381	4.148e-89	300.0	COG1028@1|root,COG1028@2|Bacteria,1G40X@1117|Cyanobacteria,1H962@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_5602311_10	1238182.C882_1029	1.009e-25	109.0	2EB0P@1|root,3351I@2|Bacteria,1NAEB@1224|Proteobacteria,2UG0E@28211|Alphaproteobacteria,2JUS0@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_5602311_7	159087.Daro_0857	9.74e-43	173.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VQEB@28216|Betaproteobacteria,2KW7W@206389|Rhodocyclales	206389|Rhodocyclales	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
PYH1_k127_5602311_1	748247.AZKH_0279	5.189e-153	506.0	COG2159@1|root,COG2159@2|Bacteria,1R7E1@1224|Proteobacteria,2VPY4@28216|Betaproteobacteria,2KVED@206389|Rhodocyclales	206389|Rhodocyclales	S	Amidohydrolase	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
PYH1_k127_5602311_0	62928.azo1036	1.476e-172	547.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,2KUQ4@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
PYH1_k127_5602311_9	1123487.KB892841_gene4313	1.56e-36	138.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,2KWYA@206389|Rhodocyclales	206389|Rhodocyclales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
PYH1_k127_5602311_3	1198452.Jab_2c19510	1.608e-130	431.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,473MT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
PYH1_k127_5602311_2	1304883.KI912532_gene1972	2.624e-150	485.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,2KUKU@206389|Rhodocyclales	206389|Rhodocyclales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
PYH1_k127_561446_8	1101191.KI912577_gene1455	8.057e-35	134.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,1JSUQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
PYH1_k127_561446_5	1207063.P24_07354	5.343e-89	304.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2TV55@28211|Alphaproteobacteria,2JRV1@204441|Rhodospirillales	204441|Rhodospirillales	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
PYH1_k127_561446_6	1121861.KB899934_gene478	1.68e-79	274.0	COG0607@1|root,COG4275@1|root,COG0607@2|Bacteria,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TRC3@28211|Alphaproteobacteria,2JPWH@204441|Rhodospirillales	204441|Rhodospirillales	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist,Rhodanese
PYH1_k127_561446_1	398578.Daci_3067	2.737e-199	641.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,4AABT@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
PYH1_k127_561446_10	485913.Krac_2054	1.564e-22	113.0	COG5470@1|root,COG5470@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
PYH1_k127_561446_7	296591.Bpro_3554	3.138e-58	213.0	COG2032@1|root,COG2032@2|Bacteria,1N26J@1224|Proteobacteria,2VT83@28216|Betaproteobacteria,4AEKN@80864|Comamonadaceae	28216|Betaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
PYH1_k127_561446_4	1000565.METUNv1_04061	4.593e-104	347.0	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2VKTA@28216|Betaproteobacteria,2KVUV@206389|Rhodocyclales	206389|Rhodocyclales	C	formate dehydrogenase	fdhC	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
PYH1_k127_561446_11	1000565.METUNv1_04060	1.515e-15	87.0	2E8DM@1|root,332S3@2|Bacteria,1ND1I@1224|Proteobacteria,2VX0K@28216|Betaproteobacteria,2KX9Z@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_561446_3	375286.mma_1969	7.223e-124	398.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VJXP@28216|Betaproteobacteria,4739G@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	fdhB	-	-	ko:K00124,ko:K07307	ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200	-	R00519,R09501	RC02555,RC02796	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_7
PYH1_k127_561446_0	62928.azo3482	0.0	1507.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,2KU82@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
PYH1_k127_561446_12	62928.azo3483	2.863e-08	58.0	2ENJT@1|root,33G76@2|Bacteria,1NMX3@1224|Proteobacteria,2VXMJ@28216|Betaproteobacteria,2KXNQ@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_561446_9	76114.ebA2939	6.407e-30	130.0	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2VJ39@28216|Betaproteobacteria,2KWS3@206389|Rhodocyclales	206389|Rhodocyclales	S	Chaperone protein TorD	torD	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
PYH1_k127_561446_2	375286.mma_1973	5.393e-188	602.0	COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2VMBE@28216|Betaproteobacteria,472MV@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
PYH1_k127_5642422_6	614083.AWQR01000031_gene2643	5.499e-53	206.0	COG3016@1|root,COG3016@2|Bacteria,1NXYQ@1224|Proteobacteria,2VTNU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
PYH1_k127_5642422_4	57918.XP_004302898.1	2.374e-80	302.0	COG1052@1|root,KOG0069@2759|Eukaryota,37IZW@33090|Viridiplantae,3G9SJ@35493|Streptophyta,4JHV1@91835|fabids	35493|Streptophyta	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009853,GO:0009854,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0043094,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.1.1.237	ko:K15919,ko:K18606	ko00130,ko00260,ko00350,ko00360,ko00630,ko00960,ko01100,ko01110,ko01130,ko01200,map00130,map00260,map00350,map00360,map00630,map00960,map01100,map01110,map01130,map01200	M00532	R01370,R01388,R03336,R03373	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH1_k127_5642422_1	1218084.BBJK01000154_gene7640	3.302e-89	300.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VK64@28216|Betaproteobacteria,1K0U3@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	hpaI	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
PYH1_k127_5642422_2	397945.Aave_1840	2.405e-85	293.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VKCY@28216|Betaproteobacteria,4A9R1@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_5642422_3	626418.bglu_1g25240	1.093e-82	290.0	COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,2VNC9@28216|Betaproteobacteria,1K1YD@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM fatty acid desaturase	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
PYH1_k127_5642422_0	257310.BB1998	5.823e-276	859.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,3T5BW@506|Alcaligenaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82,4.2.1.9	ko:K01687,ko:K22186	ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PYH1_k127_5642422_5	94624.Bpet2685	1.164e-79	273.0	COG3181@1|root,COG3181@2|Bacteria,1NP0J@1224|Proteobacteria,2VHTG@28216|Betaproteobacteria,3T2SQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_5669690_0	1538295.JY96_15065	8.129e-166	539.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1KJ3Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein	iorB2	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
PYH1_k127_5699876_0	1304883.KI912532_gene399	8.702e-176	563.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,2KVHZ@206389|Rhodocyclales	206389|Rhodocyclales	C	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4_10,POR_N,TPP_enzyme_C
PYH1_k127_5699876_1	522306.CAP2UW1_1831	1.558e-49	191.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,2VKDF@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
PYH1_k127_5707425_13	292415.Tbd_1140	7.402e-93	310.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,1KRM4@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	-	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
PYH1_k127_5707425_30	1454004.AW11_00869	1.957e-32	130.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,1KQ34@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
PYH1_k127_5707425_12	1005048.CFU_1592	2.187e-97	326.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,473FT@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
PYH1_k127_5707425_14	264198.Reut_A0963	4.806e-92	311.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1K15D@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
PYH1_k127_5707425_7	1123393.KB891327_gene379	2.859e-232	736.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,1KREK@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
PYH1_k127_5707425_20	261292.Nit79A3_2929	1.307e-65	247.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,371SU@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
PYH1_k127_5707425_6	1123354.AUDR01000018_gene1153	1.358e-233	739.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,1KS1J@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
PYH1_k127_5707425_1	580332.Slit_1076	1.489e-294	922.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,44UZF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
PYH1_k127_5707425_10	1265502.KB905936_gene2657	9.665e-166	527.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,4A9M0@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
PYH1_k127_5707425_16	1123393.KB891327_gene384	7.121e-76	290.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,1KRJR@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
PYH1_k127_5707425_17	292415.Tbd_1151	6.731e-74	262.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,1KS7Z@119069|Hydrogenophilales	119069|Hydrogenophilales	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
PYH1_k127_5707425_28	1500894.JQNN01000001_gene2090	9.982e-42	169.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,474JA@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
PYH1_k127_5707425_3	1288494.EBAPG3_21520	1.14e-278	869.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,371N6@32003|Nitrosomonadales	28216|Betaproteobacteria	C	chain 5 L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
PYH1_k127_5707425_5	497321.C664_02845	1.364e-247	771.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,2KVU3@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
PYH1_k127_5707425_8	1163617.SCD_n00952	2.544e-177	569.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
PYH1_k127_5707425_23	1005048.CFU_1606	1.942e-57	205.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,4729H@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
PYH1_k127_5707425_15	105559.Nwat_2753	2.643e-86	300.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1WX4U@135613|Chromatiales	135613|Chromatiales	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
PYH1_k127_5707425_18	1265502.KB905937_gene2562	1.648e-71	274.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHPI@28216|Betaproteobacteria,4AAUI@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
PYH1_k127_5707425_22	697282.Mettu_3435	3.262e-58	207.0	COG2128@1|root,COG2128@2|Bacteria,1RC52@1224|Proteobacteria,1S2A0@1236|Gammaproteobacteria,1XGC6@135618|Methylococcales	135618|Methylococcales	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
PYH1_k127_5707425_0	1454004.AW11_03443	0.0	1495.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,1KR73@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
PYH1_k127_5707425_26	640081.Dsui_2669	2.565e-49	186.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5,DUF4274
PYH1_k127_5707425_21	420662.Mpe_A2723	2.706e-60	215.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,1KITD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
PYH1_k127_5707425_29	1158318.ATXC01000002_gene1571	6.162e-40	159.0	COG1970@1|root,COG1970@2|Bacteria	2|Bacteria	M	mechanosensitive ion channel activity	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
PYH1_k127_5707425_4	1242864.D187_005192	3.171e-268	863.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
PYH1_k127_5707425_31	937777.Deipe_1682	2.536e-15	87.0	COG4392@1|root,COG4392@2|Bacteria,1WNCD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
PYH1_k127_5707425_25	1395571.TMS3_0106305	8.91e-50	186.0	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1S85J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Branched-chain amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
PYH1_k127_5707425_19	1123355.JHYO01000011_gene1419	2.297e-68	236.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,36YEB@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Redoxin	MA20_20905	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Redoxin
PYH1_k127_5707425_27	883126.HMPREF9710_01251	1.23e-48	177.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2VTKP@28216|Betaproteobacteria,474QB@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
PYH1_k127_5707425_24	1110502.TMO_3118	2.751e-56	211.0	COG2114@1|root,COG2114@2|Bacteria,1MVZU@1224|Proteobacteria,2U128@28211|Alphaproteobacteria,2JWF3@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
PYH1_k127_5707425_9	1163617.SCD_n02052	1.298e-170	547.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2VKNE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
PYH1_k127_5707425_2	640081.Dsui_2996	3.015e-289	898.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KV9Y@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
PYH1_k127_5707425_11	266117.Rxyl_2783	1.217e-131	458.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,2GIZF@201174|Actinobacteria,4CRHY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
PYH1_k127_5707425_32	765913.ThidrDRAFT_0914	6.289e-05	46.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1WWTV@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM Cytochrome c-type biogenesis protein CcmI	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
PYH1_k127_5728271_0	1454004.AW11_03520	9.455e-64	228.0	COG0845@1|root,COG0845@2|Bacteria,1RC4B@1224|Proteobacteria,2VSG3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
PYH1_k127_577788_7	1120999.JONM01000004_gene3626	3.714e-05	49.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,2KRTT@206351|Neisseriales	206351|Neisseriales	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
PYH1_k127_577788_0	640081.Dsui_0446	3.881e-192	619.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,2KVMW@206389|Rhodocyclales	206389|Rhodocyclales	K	RNB	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
PYH1_k127_577788_3	76114.ebA1728	1.371e-50	187.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,2VRCD@28216|Betaproteobacteria,2KWCR@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
PYH1_k127_577788_1	1265502.KB905941_gene2913	5.562e-191	606.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,4A9UY@80864|Comamonadaceae	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PYH1_k127_577788_4	62928.azo0867	5.515e-45	170.0	COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,2VJC9@28216|Betaproteobacteria,2KUIR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_577788_5	279714.FuraDRAFT_2788	1.199e-35	146.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,2KR5I@206351|Neisseriales	206351|Neisseriales	CO	Redoxin family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
PYH1_k127_577788_2	1434929.X946_1724	6.918e-51	187.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,1K5S0@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
PYH1_k127_577788_6	455436.DS989811_gene1732	2.797e-25	109.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,466TN@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iYL1228.KPN_03664	Biotin_lipoyl
PYH1_k127_5823473_4	264198.Reut_A0292	8.131e-16	77.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,1K0BN@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Ammonium transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
PYH1_k127_5823473_1	159087.Daro_3513	1.017e-83	282.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,2VMSB@28216|Betaproteobacteria,2KV5G@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome c-type protein	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
PYH1_k127_5823473_3	1121035.AUCH01000002_gene1468	1.477e-38	162.0	COG3043@1|root,COG3043@2|Bacteria,1RHGD@1224|Proteobacteria,2VTPE@28216|Betaproteobacteria,2KXA1@206389|Rhodocyclales	206389|Rhodocyclales	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	-	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
PYH1_k127_5823473_0	85643.Tmz1t_4007	8.389e-111	364.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,2VJYI@28216|Betaproteobacteria,2KUNK@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	napH	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5,Fer4_6
PYH1_k127_5823473_2	1005999.GLGR_0536	2.266e-80	269.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,1RNHT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin-type protein	napG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
PYH1_k127_5838378_0	1123367.C666_07670	9.257e-120	393.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,2KVC3@206389|Rhodocyclales	206389|Rhodocyclales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
PYH1_k127_5838378_1	640081.Dsui_1023	1.097e-88	297.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,2KVKB@206389|Rhodocyclales	206389|Rhodocyclales	D	cell division	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
PYH1_k127_5838378_2	497321.C664_16625	3.221e-27	116.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,2KUD0@206389|Rhodocyclales	206389|Rhodocyclales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
PYH1_k127_5871234_1	296591.Bpro_2800	1.279e-306	944.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VHRD@28216|Betaproteobacteria,4ABWV@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	oxc	-	4.1.1.8	ko:K01577	ko00630,ko01100,map00630,map01100	-	R01908	RC00620	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_5871234_7	296591.Bpro_2799	7.809e-79	268.0	COG0664@1|root,COG0664@2|Bacteria,1R64V@1224|Proteobacteria,2VJXN@28216|Betaproteobacteria,4ACEI@80864|Comamonadaceae	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
PYH1_k127_5871234_4	296591.Bpro_2797	1.944e-242	756.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AAW5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
PYH1_k127_5871234_9	1245469.S58_27210	8.537e-42	172.0	2BKYI@1|root,32FF5@2|Bacteria,1RB6X@1224|Proteobacteria,2VER9@28211|Alphaproteobacteria,3JY0I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	MA20_15120	-	-	-	-	-	-	-	-	-	-	-	TctB
PYH1_k127_5871234_5	1458275.AZ34_11035	7.604e-144	497.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,4AC49@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_5871234_8	381666.H16_A0549	8.744e-72	249.0	COG0861@1|root,COG0861@2|Bacteria,1QZU6@1224|Proteobacteria,2VJDD@28216|Betaproteobacteria,1KFI7@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
PYH1_k127_5871234_2	395964.KE386496_gene2969	5.23e-267	875.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,3NASQ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	F	formate-tetrahydrofolate ligase activity	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
PYH1_k127_5871234_0	977880.RALTA_B1495	0.0	1391.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,1K6SR@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA1	-	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
PYH1_k127_5871234_3	1265502.KB905958_gene233	4.614e-246	769.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,4AB8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	fdwB	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
PYH1_k127_5871234_6	279238.Saro_2884	3.657e-89	325.0	COG0121@1|root,COG0121@2|Bacteria,1PX9W@1224|Proteobacteria,2U07B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
PYH1_k127_5871234_10	1283283.ATXA01000001_gene398	2.296e-07	60.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4ES5E@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, Crp Fnr family	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH1_k127_5891845_1	292415.Tbd_1871	1.458e-198	650.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,1KRIS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
PYH1_k127_5891845_8	1163617.SCD_n02874	3.035e-70	268.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VNAG@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Glycosyl transferase family 4	wbiH	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
PYH1_k127_5891845_10	292415.Tbd_1873	1.42e-57	212.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,2VJHC@28216|Betaproteobacteria,1KTE1@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
PYH1_k127_5891845_6	1163617.SCD_n02867	6.88e-107	359.0	COG0438@1|root,COG0438@2|Bacteria,1Q8X1@1224|Proteobacteria,2VZWQ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
PYH1_k127_5891845_7	640081.Dsui_0460	7.397e-77	284.0	COG0859@1|root,COG0859@2|Bacteria,1NEWM@1224|Proteobacteria,2VQ5K@28216|Betaproteobacteria,2KW4G@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
PYH1_k127_5891845_12	1577887.JSYG01000003_gene1247	6.086e-52	202.0	COG3307@1|root,COG3307@2|Bacteria,1NDCS@1224|Proteobacteria,1SYT0@1236|Gammaproteobacteria,2JBNJ@204037|Dickeya	1236|Gammaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
PYH1_k127_5891845_9	1123400.KB904767_gene3438	1.663e-69	253.0	COG0859@1|root,COG0859@2|Bacteria,1N6DZ@1224|Proteobacteria,1SYI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
PYH1_k127_5891845_4	1163617.SCD_n02864	6.785e-125	413.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria	28216|Betaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
PYH1_k127_5891845_0	1163617.SCD_n02863	1.542e-225	719.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
PYH1_k127_5891845_11	244582.JQAK01000002_gene523	2.903e-53	203.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,47G41@766|Rickettsiales	766|Rickettsiales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	LRR_6,Sel1
PYH1_k127_5891845_5	748280.NH8B_3704	5.721e-112	373.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,2VJET@28216|Betaproteobacteria,2KQU0@206351|Neisseriales	206351|Neisseriales	M	Glycosyltransferase Family 4	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
PYH1_k127_5891845_3	159087.Daro_0152	7.907e-134	448.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VRSM@28216|Betaproteobacteria,2KVQV@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
PYH1_k127_5891845_2	1163617.SCD_n02860	3.872e-152	507.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria	28216|Betaproteobacteria	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
PYH1_k127_5891845_13	398527.Bphyt_1001	1.059e-37	156.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,1K1P1@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Periplasmic binding protein	btuF	-	-	ko:K02016,ko:K06858	ko02010,map02010	M00240,M00241	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.13,3.A.1.14	-	-	Peripla_BP_2
PYH1_k127_5923074_9	1380394.JADL01000010_gene4217	7.419e-71	247.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,2JPT9@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
PYH1_k127_5923074_8	526227.Mesil_0465	1.119e-94	317.0	COG1028@1|root,COG1028@2|Bacteria,1WIPQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
PYH1_k127_5923074_11	279714.FuraDRAFT_2004	1.62e-25	112.0	COG2050@1|root,COG2050@2|Bacteria,1N8E6@1224|Proteobacteria,2VWZG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH1_k127_5923074_7	1232410.KI421424_gene1839	4.838e-95	335.0	COG0477@1|root,COG2814@2|Bacteria,1QUY6@1224|Proteobacteria,43DH9@68525|delta/epsilon subdivisions,2X8P2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_5923074_4	1100720.ALKN01000045_gene433	1.36e-107	354.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2VHSZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH1_k127_5923074_6	1207063.P24_03740	2.542e-96	323.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,2JPS1@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the GST superfamily	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N
PYH1_k127_5923074_10	765911.Thivi_0158	6.198e-49	179.0	COG1714@1|root,COG1714@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,1WZR8@135613|Chromatiales	135613|Chromatiales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD,zinc_ribbon_2
PYH1_k127_5923074_3	485913.Krac_2660	7.769e-127	414.0	COG2130@1|root,COG2130@2|Bacteria	2|Bacteria	S	13-prostaglandin reductase activity	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
PYH1_k127_5923074_5	316058.RPB_1750	1.422e-102	345.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TSKH@28211|Alphaproteobacteria,3JR54@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	MA20_18565	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_5923074_1	1121127.JAFA01000016_gene3083	1.729e-162	521.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2VIQT@28216|Betaproteobacteria,1JZSR@119060|Burkholderiaceae	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_5923074_0	1429916.X566_10345	9.698e-168	540.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TR6X@28211|Alphaproteobacteria,3JU3Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Cytochrome P450	MA20_16575	-	-	-	-	-	-	-	-	-	-	-	p450
PYH1_k127_5923074_12	224911.27351163	1.597e-19	99.0	COG1141@1|root,COG1141@2|Bacteria,1MZJU@1224|Proteobacteria,2UCKK@28211|Alphaproteobacteria,3K07G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	MA20_16570	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
PYH1_k127_5923074_2	1298867.AUES01000039_gene813	1.367e-156	512.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3JR5T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the GMC oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
PYH1_k127_5940440_8	748247.AZKH_3561	1.558e-37	145.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,2KYX2@206389|Rhodocyclales	206389|Rhodocyclales	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
PYH1_k127_5940440_0	640081.Dsui_1936	4.181e-174	557.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,2KV5W@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
PYH1_k127_5940440_5	1265502.KB905934_gene3179	1.645e-70	245.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,4ACAI@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	ompA	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
PYH1_k127_5940440_2	1121035.AUCH01000001_gene2102	2.329e-106	349.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,2KVHW@206389|Rhodocyclales	206389|Rhodocyclales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
PYH1_k127_5940440_4	1005048.CFU_3760	1.101e-71	249.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria,473BT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	haloacid dehalogenase-like hydrolase	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PYH1_k127_5940440_3	744979.R2A130_2661	1.146e-73	267.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2U1HJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
PYH1_k127_5940440_6	930166.CD58_17475	2.062e-50	189.0	COG0845@1|root,COG0845@2|Bacteria,1R99C@1224|Proteobacteria,1RZS0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
PYH1_k127_5940440_1	930166.CD58_17470	1.675e-112	389.0	COG1538@1|root,COG1538@2|Bacteria,1MUHM@1224|Proteobacteria,1RNNS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
PYH1_k127_5940440_10	566466.NOR53_2818	3.137e-11	77.0	COG0689@1|root,COG0810@1|root,COG3210@1|root,COG4932@1|root,COG0689@2|Bacteria,COG0810@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin_3,Calx-beta,DUF11,DUF4347,He_PIG,OmpA_membrane,PATR,VCBS
PYH1_k127_5940440_7	643867.Ftrac_1239	2.155e-46	190.0	COG2911@1|root,COG4932@1|root,COG5644@1|root,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
PYH1_k127_5940440_9	568768.CM001975_gene3115	8.941e-17	95.0	COG2931@1|root,COG4625@1|root,COG2931@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,2JC9A@204037|Dickeya	1236|Gammaproteobacteria	QU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,He_PIG
PYH1_k127_5965351_0	580332.Slit_2080	1.031e-128	422.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
PYH1_k127_5965351_1	522306.CAP2UW1_4288	2.622e-61	231.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria	28216|Betaproteobacteria	V	abc transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH1_k127_5995062_10	338969.Rfer_0038	4.78e-34	143.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,4AFKW@80864|Comamonadaceae	28216|Betaproteobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
PYH1_k127_5995062_7	543913.D521_1537	7.666e-64	248.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,1KQKF@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	CO	Redoxin	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
PYH1_k127_5995062_1	640081.Dsui_1172	1.328e-276	863.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,2KUNW@206389|Rhodocyclales	206389|Rhodocyclales	O	Cytochrome c	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
PYH1_k127_5995062_8	1007105.PT7_1839	3.409e-62	219.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3T49R@506|Alcaligenaceae	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
PYH1_k127_5995062_15	1007105.PT7_1840	1.744e-06	59.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY2T@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
PYH1_k127_5995062_4	522306.CAP2UW1_0726	2.941e-120	392.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,1KQ7H@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
PYH1_k127_5995062_6	1163617.SCD_n02739	1.715e-75	261.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
PYH1_k127_5995062_9	1121035.AUCH01000025_gene3329	1.507e-59	214.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,2KW6J@206389|Rhodocyclales	206389|Rhodocyclales	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
PYH1_k127_5995062_3	748247.AZKH_0483	3.337e-159	513.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,2KU9W@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
PYH1_k127_5995062_5	272560.BPSL2361	7.902e-95	334.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2VISF@28216|Betaproteobacteria,1K2H9@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
PYH1_k127_5995062_12	76114.ebA3590	5.208e-24	111.0	COG3154@1|root,COG3154@2|Bacteria,1RB7T@1224|Proteobacteria,2VTWW@28216|Betaproteobacteria,2KXAD@206389|Rhodocyclales	206389|Rhodocyclales	I	lipid carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
PYH1_k127_5995062_11	279714.FuraDRAFT_1002	5.046e-30	123.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_5995062_2	159087.Daro_3260	1.823e-239	750.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,2VIU7@28216|Betaproteobacteria,2KU6N@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome	nirN	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Cytochrome_CBB3
PYH1_k127_5995062_0	1121035.AUCH01000016_gene2118	2.815e-294	911.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria,2KVT2@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome D1 heme domain	nirS	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
PYH1_k127_5995062_14	1123393.KB891316_gene1486	3.13e-10	69.0	COG0425@1|root,COG0425@2|Bacteria,1QU8C@1224|Proteobacteria,2WGIR@28216|Betaproteobacteria,1KTES@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
PYH1_k127_5995062_13	243365.CV_2710	4.973e-18	93.0	COG3945@1|root,COG3945@2|Bacteria,1N383@1224|Proteobacteria,2VUXI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
PYH1_k127_5997567_24	1038869.AXAN01000022_gene1914	1.021e-14	76.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,2VJAI@28216|Betaproteobacteria,1K2BP@119060|Burkholderiaceae	28216|Betaproteobacteria	MV	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH1_k127_5997567_21	1230343.CANP01000001_gene4	3.538e-68	248.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
PYH1_k127_5997567_2	1100720.ALKN01000035_gene995	2.33e-214	678.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2VIY8@28216|Betaproteobacteria,4AHFM@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
PYH1_k127_5997567_10	640510.BC1001_1732	3.395e-125	413.0	COG0604@1|root,COG0604@2|Bacteria,1MU4N@1224|Proteobacteria,2VIU4@28216|Betaproteobacteria,1JZTH@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily	-	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
PYH1_k127_5997567_0	1123393.KB891317_gene2344	5.439e-266	828.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,1KRCR@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA synthetases class I (E and Q), anti-codon binding domain	-	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
PYH1_k127_5997567_20	1205680.CAKO01000038_gene1573	6.26e-73	259.0	COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2U0AF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	ET	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PYH1_k127_5997567_18	1382303.JPOM01000001_gene2474	2.242e-75	271.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2TSSU@28211|Alphaproteobacteria,2KFK9@204458|Caulobacterales	204458|Caulobacterales	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH1_k127_5997567_3	1121106.JQKB01000010_gene445	2.544e-164	544.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,2JRVP@204441|Rhodospirillales	204441|Rhodospirillales	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253	ko00980,ko04976,ko05204,map00980,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
PYH1_k127_5997567_1	1317118.ATO8_16910	2.622e-226	708.0	COG1524@1|root,COG1524@2|Bacteria,1P235@1224|Proteobacteria,2U2XB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
PYH1_k127_5997567_16	864051.BurJ1DRAFT_1464	3.867e-78	277.0	28JEH@1|root,2Z98N@2|Bacteria,1RIK2@1224|Proteobacteria,2VWXE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_5997567_4	1317118.ATO8_16900	1.861e-156	506.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria,2TUE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TatD related DNase	-	-	-	-	-	-	-	-	-	-	-	-	TatD_DNase
PYH1_k127_5997567_14	1094980.Mpsy_0015	3.981e-91	316.0	COG2133@1|root,COG3794@1|root,arCOG10180@1|root,arCOG02796@2157|Archaea,arCOG02929@2157|Archaea,arCOG10180@2157|Archaea,2XT1Q@28890|Euryarchaeota,2NADP@224756|Methanomicrobia	224756|Methanomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
PYH1_k127_5997567_25	305700.B447_18418	0.0002475	49.0	COG2010@1|root,COG2010@2|Bacteria,1N4RA@1224|Proteobacteria,2VVFA@28216|Betaproteobacteria,2KZ0A@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH1_k127_5997567_5	864051.BurJ1DRAFT_1462	5.796e-153	493.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,1KK3W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.152,4.2.3.4	ko:K01735,ko:K19969	ko00400,ko00525,ko01100,ko01110,ko01130,ko01230,map00400,map00525,map01100,map01110,map01130,map01230	M00022,M00814,M00815	R03083,R10937	RC00847,RC03308	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
PYH1_k127_5997567_7	864051.BurJ1DRAFT_1461	5.823e-130	444.0	COG1082@1|root,COG1082@2|Bacteria,1NHXC@1224|Proteobacteria,2VRSG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
PYH1_k127_5997567_19	864051.BurJ1DRAFT_1460	3.51e-75	278.0	COG0382@1|root,COG0382@2|Bacteria,1RFNQ@1224|Proteobacteria,2W5W3@28216|Betaproteobacteria	28216|Betaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
PYH1_k127_5997567_17	504832.OCAR_6697	4.6e-78	271.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,3JRS0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.1.1.41,4.2.1.17	ko:K01692,ko:K11264	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R00923,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00097,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH1_k127_5997567_15	266264.Rmet_4101	6.082e-82	282.0	COG3181@1|root,COG3181@2|Bacteria,1NU2D@1224|Proteobacteria,2VMNN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_5997567_12	1207063.P24_10011	1.508e-108	356.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2TQYY@28211|Alphaproteobacteria,2JRNC@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH1_k127_5997567_22	1380394.JADL01000002_gene1513	1.14e-60	219.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,2TU31@28211|Alphaproteobacteria,2JS0A@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
PYH1_k127_5997567_13	1298867.AUES01000002_gene1301	2.083e-105	357.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TUKJ@28211|Alphaproteobacteria,3JUMA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	MA20_30645	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
PYH1_k127_5997567_11	472759.Nhal_3413	4.587e-109	366.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1X250@135613|Chromatiales	135613|Chromatiales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
PYH1_k127_5997567_9	479434.Sthe_2663	2.834e-126	432.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27XJ3@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PYH1_k127_5997567_23	1121920.AUAU01000006_gene256	3.692e-42	174.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	plsC2	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
PYH1_k127_5997567_6	414684.RC1_0409	1.692e-133	435.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2U55H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
PYH1_k127_5997567_8	1380394.JADL01000013_gene686	1.319e-126	409.0	COG1063@1|root,COG1063@2|Bacteria,1QTU5@1224|Proteobacteria,2TW9Q@28211|Alphaproteobacteria,2JQP9@204441|Rhodospirillales	204441|Rhodospirillales	E	Alanine dehydrogenase/PNT, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_6022963_2	1121035.AUCH01000002_gene1478	1.82e-75	259.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,2KVF9@206389|Rhodocyclales	206389|Rhodocyclales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
PYH1_k127_6022963_0	748247.AZKH_3449	6.419e-105	350.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,2KUD4@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
PYH1_k127_6022963_3	557598.LHK_03116	1.271e-53	198.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VSGQ@28216|Betaproteobacteria,2KRD6@206351|Neisseriales	206351|Neisseriales	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PYH1_k127_6022963_1	795666.MW7_2046	6.001e-102	343.0	COG3181@1|root,COG3181@2|Bacteria,1R8DS@1224|Proteobacteria,2W1MT@28216|Betaproteobacteria,1K4EH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_6022963_4	743721.Psesu_2564	4.986e-07	51.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales	135614|Xanthomonadales	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
PYH1_k127_6058238_4	396588.Tgr7_3220	4.075e-27	116.0	COG5573@1|root,COG5573@2|Bacteria,1RDSH@1224|Proteobacteria	1224|Proteobacteria	S	nucleic-acid-binding protein contains PIN domain	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
PYH1_k127_6058238_3	331869.BAL199_10300	2.158e-81	280.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TTP8@28211|Alphaproteobacteria,4BRVG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
PYH1_k127_6058238_2	118161.KB235922_gene1489	2.421e-95	324.0	COG3836@1|root,COG3836@2|Bacteria,1GIQ1@1117|Cyanobacteria,3VKIC@52604|Pleurocapsales	1117|Cyanobacteria	G	PFAM HpcH HpaI aldolase citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
PYH1_k127_6058238_0	1217718.ALOU01000038_gene3330	6.799e-179	574.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,1K51A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3,SLT
PYH1_k127_6058238_5	207559.Dde_3506	0.0003498	50.0	2B23H@1|root,31UKH@2|Bacteria,1QSFX@1224|Proteobacteria,436V3@68525|delta/epsilon subdivisions,2X1J5@28221|Deltaproteobacteria,2MF64@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4410)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4410
PYH1_k127_6058238_1	887898.HMPREF0551_2591	8.923e-149	483.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,1K219@119060|Burkholderiaceae	28216|Betaproteobacteria	S	abc transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
PYH1_k127_6065580_1	296591.Bpro_2800	0.0	1004.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VHRD@28216|Betaproteobacteria,4ABWV@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	oxc	-	4.1.1.8	ko:K01577	ko00630,ko01100,map00630,map01100	-	R01908	RC00620	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_6065580_2	375286.mma_2347	1.495e-185	596.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,476TX@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	CoA-transferase family III	-	-	2.8.3.16,2.8.3.22	ko:K07749,ko:K14471,ko:K14472	ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200	M00376	R00406,R03154	RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
PYH1_k127_6065580_3	1096546.WYO_3029	4.747e-122	419.0	COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria,2U0GD@28211|Alphaproteobacteria,1JSQ7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	PFAM formyl transferase domain protein	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
PYH1_k127_6065580_0	640081.Dsui_1449	0.0	1163.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
PYH1_k127_6065580_4	640081.Dsui_1450	2.555e-105	351.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,2KUQG@206389|Rhodocyclales	206389|Rhodocyclales	T	Serine/threonine phosphatases, family 2C, catalytic domain	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
PYH1_k127_6065580_5	1000565.METUNv1_02453	2.245e-53	191.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
PYH1_k127_6077135_6	159087.Daro_0718	7.406e-22	100.0	COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,2VTYE@28216|Betaproteobacteria,2KX1A@206389|Rhodocyclales	206389|Rhodocyclales	S	FixH family	-	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
PYH1_k127_6077135_1	1286631.X805_32530	2.443e-186	609.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,1KIYJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	cytochrome C oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
PYH1_k127_6077135_3	596154.Alide2_1122	6.386e-113	371.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4A9QA@80864|Comamonadaceae	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
PYH1_k127_6077135_8	1117647.M5M_08005	6.11e-08	63.0	COG4736@1|root,COG4736@2|Bacteria,1QEFV@1224|Proteobacteria,1TB54@1236|Gammaproteobacteria,1J781@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG4736 Cbb3-type cytochrome oxidase, subunit 3	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
PYH1_k127_6077135_4	1132855.KB913035_gene2297	1.702e-94	313.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,2KMM8@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM cytochrome C oxidase mono-heme subunit FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
PYH1_k127_6077135_0	62928.azo1341	1.392e-267	841.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,2KVB2@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
PYH1_k127_6077135_2	266117.Rxyl_0056	2.396e-141	457.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4CPC1@84995|Rubrobacteria	84995|Rubrobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
PYH1_k127_6077135_7	640081.Dsui_1626	7.474e-10	70.0	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,2VWG5@28216|Betaproteobacteria,2KX6C@206389|Rhodocyclales	206389|Rhodocyclales	P	cytochrome oxidase maturation protein cbb3-type	-	-	-	-	-	-	-	-	-	-	-	-	FixS
PYH1_k127_6077135_5	519989.ECTPHS_06582	5.28e-81	281.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WXM6@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
PYH1_k127_6096351_3	1304883.KI912532_gene1599	2.658e-21	94.0	COG0261@1|root,COG0261@2|Bacteria	2|Bacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
PYH1_k127_6096351_2	944435.AXAJ01000017_gene2785	5.867e-31	123.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,1K8IM@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
PYH1_k127_6096351_0	1163617.SCD_n02108	5.65e-148	476.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
PYH1_k127_6096351_1	1231391.AMZF01000110_gene855	1.391e-98	325.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,3T1MI@506|Alcaligenaceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
PYH1_k127_6163330_11	1297742.A176_05036	1.963e-05	47.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
PYH1_k127_6163330_4	1005048.CFU_2593	8.603e-98	338.0	COG0477@1|root,COG2814@2|Bacteria,1R3YS@1224|Proteobacteria,2VQBS@28216|Betaproteobacteria,473XW@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_6163330_3	1082933.MEA186_01908	4.617e-101	348.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_11,TPR_16,TPR_8,Trans_reg_C
PYH1_k127_6163330_5	1131814.JAFO01000001_gene499	1.655e-85	292.0	COG0596@1|root,COG0596@2|Bacteria,1R3U1@1224|Proteobacteria,2TVFV@28211|Alphaproteobacteria,3F014@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
PYH1_k127_6163330_8	1265505.ATUG01000002_gene2436	2.138e-47	181.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2MJ7B@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
PYH1_k127_6163330_6	1205680.CAKO01000007_gene4246	5.097e-80	292.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_6163330_2	1037409.BJ6T_16460	5.019e-112	370.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,2U933@28211|Alphaproteobacteria,3JWI1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
PYH1_k127_6163330_7	580332.Slit_0323	7.19e-59	224.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6163330_9	1128421.JAGA01000002_gene1413	2.373e-47	181.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc
PYH1_k127_6163330_1	614083.AWQR01000011_gene2381	3.779e-145	465.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	dhmA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_6163330_0	1038859.AXAU01000001_gene2923	0.0	1306.0	28JZZ@1|root,2Z9PZ@2|Bacteria,1N3C6@1224|Proteobacteria,2TSCX@28211|Alphaproteobacteria,3K36I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6163330_10	159087.Daro_3859	1.401e-44	171.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,2KWMI@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome c5	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH1_k127_6163330_12	316055.RPE_0600	0.0001026	48.0	COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,2U6JY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PYH1_k127_6178676_0	1288494.EBAPG3_26320	7.972e-276	881.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,37225@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
PYH1_k127_6178676_1	36809.MAB_1554	1.059e-06	62.0	COG0664@1|root,COG1670@1|root,COG0664@2|Bacteria,COG1670@2|Bacteria,2HNCU@201174|Actinobacteria,234EN@1762|Mycobacteriaceae	201174|Actinobacteria	JT	cyclic nucleotide-binding	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,cNMP_binding
PYH1_k127_6179671_2	640081.Dsui_0121	1.487e-62	219.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,2KV1D@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
PYH1_k127_6179671_0	402626.Rpic_3146	4.481e-158	514.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,1K2D1@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
PYH1_k127_6179671_1	1349767.GJA_5181	4.689e-64	246.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,473AP@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
PYH1_k127_6179671_4	640081.Dsui_0118	1.864e-47	172.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,2KWQF@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
PYH1_k127_6179671_3	195250.CM001776_gene2457	2.032e-62	219.0	COG3001@1|root,COG3001@2|Bacteria,1G040@1117|Cyanobacteria,1GZY8@1129|Synechococcus	1117|Cyanobacteria	G	COG3001 Fructosamine-3-kinase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
PYH1_k127_6246810_0	1123392.AQWL01000003_gene209	6.174e-174	556.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,1KSNJ@119069|Hydrogenophilales	119069|Hydrogenophilales	GM	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer,NTP_transferase
PYH1_k127_6246810_1	314345.SPV1_00240	7.326e-96	341.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
PYH1_k127_6246810_4	1132855.KB913035_gene1654	5.038e-66	240.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.412,5.1.3.26	ko:K19997,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
PYH1_k127_6246810_3	1123392.AQWL01000001_gene1559	1.023e-80	279.0	COG1216@1|root,COG1216@2|Bacteria,1RB30@1224|Proteobacteria,2VQYN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
PYH1_k127_6246810_2	331113.SNE_A01460	4.994e-88	304.0	2DVVI@1|root,33XD7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6246810_5	1205680.CAKO01000010_gene4009	2.274e-65	232.0	COG2242@1|root,COG2242@2|Bacteria,1QX6B@1224|Proteobacteria,2TZAR@28211|Alphaproteobacteria,2JUEP@204441|Rhodospirillales	204441|Rhodospirillales	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
PYH1_k127_6250859_0	644966.Tmar_0825	1.013e-165	531.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WCD0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
PYH1_k127_6250859_1	204669.Acid345_0713	1.156e-41	156.0	COG0290@1|root,COG0290@2|Bacteria,3Y3VP@57723|Acidobacteria,2JIGK@204432|Acidobacteriia	204432|Acidobacteriia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
PYH1_k127_6275541_0	1499502.EV12_0046	8.356e-165	535.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	asdA	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
PYH1_k127_6275541_3	1038866.KB902771_gene3755	1.038e-104	361.0	COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria,2TRJ8@28211|Alphaproteobacteria,3JTBC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	MA20_22460	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
PYH1_k127_6275541_4	1472716.KBK24_0102910	6.514e-93	316.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2VV9X@28216|Betaproteobacteria,1K8N9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
PYH1_k127_6275541_9	338963.Pcar_0433	8.237e-10	67.0	COG2913@1|root,COG2913@2|Bacteria,1NMHT@1224|Proteobacteria,433NP@68525|delta/epsilon subdivisions,2WX9S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6275541_8	195105.CN97_00595	4.149e-57	204.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2U98I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	N-acetyltransferase	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
PYH1_k127_6275541_1	388051.AUFE01000009_gene1751	2.334e-126	412.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2VJ1C@28216|Betaproteobacteria,1K27J@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_6275541_5	243924.LT42_16390	4.487e-91	314.0	COG0625@1|root,COG0625@2|Bacteria,1P71B@1224|Proteobacteria,1RQZH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
PYH1_k127_6275541_6	1268622.AVS7_03447	3.061e-81	291.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_6275541_7	1298867.AUES01000016_gene3933	6.039e-80	273.0	COG4221@1|root,COG4221@2|Bacteria,1QW75@1224|Proteobacteria,2TWQR@28211|Alphaproteobacteria,3JTEM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	KR domain	MA20_16520	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_6275541_2	1380394.JADL01000010_gene4354	3.255e-116	380.0	COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2TR54@28211|Alphaproteobacteria,2JV21@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
PYH1_k127_6284681_4	1112217.PPL19_20766	4.445e-17	83.0	COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	-	-	ko:K13053,ko:K14160	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	RecA,SulA
PYH1_k127_6284681_1	113395.AXAI01000003_gene5747	1.306e-32	132.0	COG3631@1|root,COG3631@2|Bacteria,1P5A2@1224|Proteobacteria,2TV5B@28211|Alphaproteobacteria,3JR2U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SnoaL-like domain	MA20_24415	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
PYH1_k127_6284681_2	522306.CAP2UW1_4305	8.591e-19	93.0	2E4IS@1|root,32ZDU@2|Bacteria,1N7N3@1224|Proteobacteria,2VVSI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM PsiF repeat protein	psiF	-	-	-	-	-	-	-	-	-	-	-	PsiF_repeat
PYH1_k127_6284681_0	32049.SYNPCC7002_A1141	1.462e-51	192.0	2DM15@1|root,319QS@2|Bacteria	2|Bacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
PYH1_k127_6284681_3	762966.HMPREF9439_01519	4.056e-18	83.0	2DP8N@1|root,3311E@2|Bacteria,1NC4X@1224|Proteobacteria,2W5UY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6338308_1	1123393.KB891316_gene1548	1.878e-55	198.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,1KT3H@119069|Hydrogenophilales	119069|Hydrogenophilales	P	ApaG domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF525
PYH1_k127_6338308_0	667632.KB890170_gene3629	3.872e-102	336.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,1K37J@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
PYH1_k127_6338308_2	1288494.EBAPG3_26500	1.897e-26	111.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,372HF@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
PYH1_k127_6363115_23	1005048.CFU_0475	1.28e-59	209.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,4744R@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
PYH1_k127_6363115_10	159087.Daro_0482	3.264e-124	412.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,2KUZ2@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
PYH1_k127_6363115_0	1000565.METUNv1_03923	0.0	1438.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,2KUQF@206389|Rhodocyclales	206389|Rhodocyclales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
PYH1_k127_6363115_25	1380394.JADL01000008_gene3636	1.848e-51	186.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2U9U1@28211|Alphaproteobacteria,2JT0G@204441|Rhodospirillales	204441|Rhodospirillales	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH1_k127_6363115_29	1532557.JL37_26935	8.014e-37	148.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VQID@28216|Betaproteobacteria,3T48U@506|Alcaligenaceae	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
PYH1_k127_6363115_2	1123354.AUDR01000015_gene324	1.889e-259	816.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,1KSEC@119069|Hydrogenophilales	1224|Proteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1,6.2.1.16	ko:K01895,ko:K01907	ko00010,ko00280,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00280,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354,R01357	RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
PYH1_k127_6363115_11	1038858.AXBA01000011_gene1437	6.607e-114	375.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TTXX@28211|Alphaproteobacteria,3F1W5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	gltI	-	-	ko:K02030,ko:K10001	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	SBP_bac_3
PYH1_k127_6363115_15	1038858.AXBA01000011_gene1438	1.307e-93	314.0	COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2TRAT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	MA20_06175	-	-	ko:K10003	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
PYH1_k127_6363115_13	1005048.CFU_3979	4.411e-98	337.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2VIQB@28216|Betaproteobacteria,472NM@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	gltK	-	-	ko:K10002	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
PYH1_k127_6363115_8	977880.RALTA_A0431	1.053e-127	411.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,1JZV5@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	gltL	-	-	ko:K10004	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	ABC_tran
PYH1_k127_6363115_24	525904.Tter_1979	1.986e-59	217.0	COG2084@1|root,COG2084@2|Bacteria,2NP96@2323|unclassified Bacteria	2|Bacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	MA20_29235	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
PYH1_k127_6363115_3	404589.Anae109_1032	1.488e-223	726.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
PYH1_k127_6363115_5	1380391.JIAS01000013_gene3817	5.022e-206	665.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,2JQBQ@204441|Rhodospirillales	204441|Rhodospirillales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_6363115_12	1095769.CAHF01000022_gene349	2.946e-99	339.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2VPP7@28216|Betaproteobacteria,4724Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
PYH1_k127_6363115_27	1380355.JNIJ01000013_gene369	4.253e-42	157.0	2E5W4@1|root,330K6@2|Bacteria,1N893@1224|Proteobacteria,2UGUZ@28211|Alphaproteobacteria,3K16Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
PYH1_k127_6363115_22	1123367.C666_14400	1.97e-66	229.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,2KWFV@206389|Rhodocyclales	206389|Rhodocyclales	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
PYH1_k127_6363115_26	358220.C380_16260	7.683e-44	171.0	COG2207@1|root,COG2207@2|Bacteria,1MUV5@1224|Proteobacteria,2VZX2@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PYH1_k127_6363115_4	395493.BegalDRAFT_0308	4.531e-207	650.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,4602W@72273|Thiotrichales	72273|Thiotrichales	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
PYH1_k127_6363115_9	1169143.KB911035_gene1794	1.701e-125	421.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2VM08@28216|Betaproteobacteria,1K6AP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Zinc-binding dehydrogenase	adh	-	1.1.1.1,1.1.1.258	ko:K12957,ko:K13953,ko:K19961	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00930,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00930,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R05283,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_6363115_18	903818.KI912268_gene852	3.048e-84	300.0	COG2834@1|root,COG4249@1|root,COG2834@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	lolA	-	-	ko:K03634,ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	Cadherin,LolA,PPC,Peptidase_C14
PYH1_k127_6363115_1	1380386.JIAW01000003_gene445	1.63e-261	816.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,2354G@1762|Mycobacteriaceae	201174|Actinobacteria	E	gamma-glutamyltransferase	ggtA	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
PYH1_k127_6363115_21	1301098.PKB_3521	1.068e-71	269.0	COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,1S2K3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-Transferase	yliJ	GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
PYH1_k127_6363115_19	1217718.ALOU01000037_gene2033	4.237e-84	290.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,1K6J1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	zinc protease protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
PYH1_k127_6363115_30	84531.JMTZ01000073_gene2105	2.513e-35	154.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria,1X6RA@135614|Xanthomonadales	135614|Xanthomonadales	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Abhydrolase_8
PYH1_k127_6363115_16	1238182.C882_3866	2.433e-92	317.0	COG2271@1|root,COG2271@2|Bacteria,1R8Q1@1224|Proteobacteria,2U16E@28211|Alphaproteobacteria,2JRZF@204441|Rhodospirillales	204441|Rhodospirillales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_6363115_14	1380394.JADL01000010_gene4335	6.058e-94	318.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,2JQKY@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
PYH1_k127_6363115_28	589865.DaAHT2_0713	1.018e-37	158.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,42RYV@68525|delta/epsilon subdivisions,2WNEF@28221|Deltaproteobacteria,2MNZ5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_6363115_7	640081.Dsui_2542	2.636e-157	511.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,2KV7J@206389|Rhodocyclales	206389|Rhodocyclales	C	glycolate oxidase subunit GlcD	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
PYH1_k127_6363115_6	414684.RC1_2397	1.403e-162	533.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,2JRI5@204441|Rhodospirillales	204441|Rhodospirillales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like
PYH1_k127_6363115_20	640081.Dsui_0624	7.304e-84	290.0	COG4243@1|root,COG4243@2|Bacteria,1MW9C@1224|Proteobacteria,2VPG2@28216|Betaproteobacteria,2KU9P@206389|Rhodocyclales	206389|Rhodocyclales	S	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6363115_31	1123392.AQWL01000005_gene2958	8.463e-25	115.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2VUA0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
PYH1_k127_6363115_17	795666.MW7_3395	6.861e-92	310.0	COG0028@1|root,COG0028@2|Bacteria,1R6FF@1224|Proteobacteria,2WF6X@28216|Betaproteobacteria,1KHZB@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_6368546_2	1187851.A33M_4209	1.662e-96	340.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
PYH1_k127_6368546_1	1049564.TevJSym_bb00040	8.297e-102	340.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
PYH1_k127_6368546_0	1049564.TevJSym_bb00050	1.196e-167	539.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
PYH1_k127_6370373_11	697282.Mettu_0851	4.986e-13	81.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XGIM@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM type I secretion membrane fusion protein, HlyD	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
PYH1_k127_6370373_2	1123228.AUIH01000054_gene3592	4.759e-227	723.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales	135619|Oceanospirillales	V	(ABC) transporter	-	-	-	ko:K11004,ko:K13409	ko02010,ko03070,ko04626,ko05133,map02010,map03070,map04626,map05133	M00325,M00339,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2,3.A.1.110	-	-	ABC_membrane,ABC_tran,Peptidase_C39
PYH1_k127_6370373_12	240016.ABIZ01000001_gene2873	9.946e-07	61.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
PYH1_k127_6370373_3	1298867.AUES01000033_gene2110	2.964e-176	559.0	COG0683@1|root,COG0683@2|Bacteria,1MV3Y@1224|Proteobacteria,2TU2B@28211|Alphaproteobacteria,3JQS1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	MA20_07775	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_6370373_5	316055.RPE_4213	6.539e-135	434.0	COG0559@1|root,COG0559@2|Bacteria,1NQYP@1224|Proteobacteria,2TSH6@28211|Alphaproteobacteria,3JTVZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	MA20_07780	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_6370373_6	1429916.X566_17315	4.327e-127	420.0	COG4177@1|root,COG4177@2|Bacteria,1MYF5@1224|Proteobacteria,2TUHM@28211|Alphaproteobacteria,3JS6G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	MA20_07785	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_6370373_7	319003.Bra1253DRAFT_07293	5.72e-114	374.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSIU@28211|Alphaproteobacteria,3JSQI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	MA20_07790	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_6370373_8	1336208.JADY01000015_gene1310	1.443e-99	331.0	COG0410@1|root,COG0410@2|Bacteria,1MUFR@1224|Proteobacteria,2TUBS@28211|Alphaproteobacteria,2JS1R@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_6370373_1	595537.Varpa_4527	1.32e-229	717.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,4ACB3@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_6370373_9	1380394.JADL01000001_gene2235	1.478e-78	267.0	COG3090@1|root,COG3090@2|Bacteria,1NDFB@1224|Proteobacteria,2U1K8@28211|Alphaproteobacteria,2JXZV@204441|Rhodospirillales	204441|Rhodospirillales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_6370373_4	595537.Varpa_4525	2.071e-175	556.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VHPP@28216|Betaproteobacteria,4ABME@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_6370373_10	1206777.B195_06435	5.197e-21	103.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1Z620@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	gltR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH1_k127_6370373_0	640081.Dsui_1209	1.28e-283	886.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,2KVA2@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
PYH1_k127_6403016_0	640081.Dsui_0112	2.472e-161	523.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,2KU89@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
PYH1_k127_6403016_1	1500894.JQNN01000001_gene2999	2.108e-27	113.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,472JW@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
PYH1_k127_6409310_1	1207063.P24_00635	8.791e-202	642.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2JP87@204441|Rhodospirillales	204441|Rhodospirillales	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH1_k127_6409310_4	762376.AXYL_05795	6.09e-133	457.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VJJK@28216|Betaproteobacteria,3T3TS@506|Alcaligenaceae	28216|Betaproteobacteria	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
PYH1_k127_6409310_5	1192034.CAP_5172	2.932e-78	278.0	COG2114@1|root,COG2114@2|Bacteria,1MY09@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE3,Guanylate_cyc
PYH1_k127_6409310_9	105559.Nwat_1638	1.103e-30	133.0	2EAWX@1|root,334Y4@2|Bacteria,1P2TY@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6409310_7	570952.ATVH01000017_gene1779	6.963e-42	156.0	COG2329@1|root,COG2329@2|Bacteria,1RGVV@1224|Proteobacteria,2U9A3@28211|Alphaproteobacteria,2JTA8@204441|Rhodospirillales	204441|Rhodospirillales	S	enzyme involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
PYH1_k127_6409310_2	420246.GTNG_1356	1.351e-176	580.0	COG0318@1|root,COG0318@2|Bacteria,1TS8T@1239|Firmicutes,4HAP4@91061|Bacilli,1WEQ4@129337|Geobacillus	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	fadD3	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_6409310_0	864051.BurJ1DRAFT_0065	5.204e-222	693.0	COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,2VPJI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Selenium-binding protein	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
PYH1_k127_6409310_6	1198452.Jab_2c22440	9.133e-58	208.0	COG1999@1|root,COG1999@2|Bacteria,1MZAW@1224|Proteobacteria	1224|Proteobacteria	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
PYH1_k127_6409310_3	1123392.AQWL01000007_gene977	2.749e-139	462.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2VI1Z@28216|Betaproteobacteria,1KRR6@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
PYH1_k127_6409310_8	296591.Bpro_1913	3.74e-32	136.0	COG0697@1|root,COG0697@2|Bacteria,1Q1CJ@1224|Proteobacteria,2W6HP@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_6410827_18	381666.H16_A1522	1.951e-79	271.0	COG4177@1|root,COG4177@2|Bacteria,1MY3V@1224|Proteobacteria,2VJIE@28216|Betaproteobacteria,1K0XJ@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH1_k127_6410827_13	402626.Rpic_1451	9.16e-108	366.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VIKW@28216|Betaproteobacteria,1JZVH@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_6410827_12	1265502.KB905940_gene3000	1.588e-109	359.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VINK@28216|Betaproteobacteria,4A9WA@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_6410827_21	1415778.JQMM01000001_gene1041	9.166e-28	130.0	2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria,1JAHP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6410827_3	414684.RC1_0226	3.967e-211	667.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,2JZIB@204441|Rhodospirillales	204441|Rhodospirillales	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
PYH1_k127_6410827_15	391735.Veis_1099	1.777e-87	297.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2VNGN@28216|Betaproteobacteria,4AJ8R@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_6410827_6	748247.AZKH_4180	1.2e-157	541.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2VHD1@28216|Betaproteobacteria,2KVBD@206389|Rhodocyclales	206389|Rhodocyclales	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
PYH1_k127_6410827_0	1031711.RSPO_c01795	5.763e-274	859.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,1JZX3@119060|Burkholderiaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-coa dehydrogenase	fadB	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
PYH1_k127_6410827_4	626887.J057_08491	6.989e-172	550.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,4643C@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH1_k127_6410827_20	1123072.AUDH01000005_gene1663	8.014e-78	285.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JSUV@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_6410827_14	1469245.JFBG01000072_gene74	2.046e-103	351.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1RYQS@1236|Gammaproteobacteria,1WWAX@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
PYH1_k127_6410827_7	1205680.CAKO01000037_gene1234	7.405e-153	511.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2JPY3@204441|Rhodospirillales	204441|Rhodospirillales	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH1_k127_6410827_2	439235.Dalk_3104	4.728e-213	694.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MIAR@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
PYH1_k127_6410827_11	439235.Dalk_3105	4.273e-113	372.0	COG0411@1|root,COG0411@2|Bacteria,1R9G9@1224|Proteobacteria,42QH8@68525|delta/epsilon subdivisions,2WKUJ@28221|Deltaproteobacteria,2MNGW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_6410827_17	986075.CathTA2_1528	2.994e-84	286.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PYH1_k127_6410827_10	439235.Dalk_3103	8.221e-115	393.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria,2MJX3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_6410827_16	986075.CathTA2_1530	3.188e-85	291.0	COG0559@1|root,COG0559@2|Bacteria	2|Bacteria	E	leucine import across plasma membrane	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_6410827_9	439235.Dalk_3101	3.207e-115	384.0	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,42UB1@68525|delta/epsilon subdivisions,2WQ1B@28221|Deltaproteobacteria,2MNNK@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_6410827_8	1095769.CAHF01000006_gene1763	5.978e-151	485.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2VIJB@28216|Betaproteobacteria,4724J@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_6410827_1	1095769.CAHF01000006_gene1762	4.174e-215	678.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHQD@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Aldehyde dehydrogenase	betB	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH1_k127_6410827_5	365046.Rta_05870	3.718e-160	508.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP8D@28216|Betaproteobacteria,4AGBG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_6410827_19	1121106.JQKB01000013_gene5558	1.885e-78	271.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TSX8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
PYH1_k127_6422341_2	546268.NEISUBOT_03120	7.326e-19	90.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
PYH1_k127_6422341_1	62928.azo1668	5.644e-81	282.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2VKZJ@28216|Betaproteobacteria,2KUQT@206389|Rhodocyclales	206389|Rhodocyclales	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	DUF4072,HAD
PYH1_k127_6422341_0	864051.BurJ1DRAFT_2886	7.405e-245	762.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,2VJ62@28216|Betaproteobacteria,1KN36@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH1_k127_6422505_2	331869.BAL199_10637	3.023e-109	360.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2TUFG@28211|Alphaproteobacteria,4BPT0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	redB	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
PYH1_k127_6422505_0	1380391.JIAS01000018_gene838	1.042e-181	576.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,2TSTV@28211|Alphaproteobacteria,2JRG0@204441|Rhodospirillales	204441|Rhodospirillales	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
PYH1_k127_6422505_3	89187.ISM_08280	1.057e-14	82.0	COG0603@1|root,COG0603@2|Bacteria,1P4ZP@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6422505_1	1123257.AUFV01000012_gene3004	1.196e-122	407.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1X5EM@135614|Xanthomonadales	135614|Xanthomonadales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
PYH1_k127_6422505_4	1123487.KB892839_gene225	0.0002798	43.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,2KUDE@206389|Rhodocyclales	206389|Rhodocyclales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
PYH1_k127_6444142_12	395495.Lcho_1194	1.395e-29	118.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,1KJ75@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM Electron transfer flavoprotein alpha beta-subunit	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
PYH1_k127_6444142_11	1217720.ALOX01000059_gene2778	6.342e-42	164.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2U7NP@28211|Alphaproteobacteria,2JS9M@204441|Rhodospirillales	204441|Rhodospirillales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
PYH1_k127_6444142_0	420324.KI912069_gene6401	6.67e-209	662.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,1JQVF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_6444142_6	1121106.JQKB01000091_gene1655	9.33e-97	339.0	COG1173@1|root,COG1173@2|Bacteria,1MVHY@1224|Proteobacteria,2TQVQ@28211|Alphaproteobacteria,2JQEY@204441|Rhodospirillales	204441|Rhodospirillales	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PYH1_k127_6444142_5	488538.SAR116_0602	4.421e-129	419.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRH6@28211|Alphaproteobacteria,4BQ46@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH1_k127_6444142_1	69279.BG36_09610	3.345e-185	595.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TS14@28211|Alphaproteobacteria,43IAX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ABC-type dipeptide transport system periplasmic component	MA20_19540	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH1_k127_6444142_8	1157490.EL26_20165	3.633e-59	218.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
PYH1_k127_6444142_10	404589.Anae109_1750	5.054e-42	160.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PYH1_k127_6444142_4	266264.Rmet_5086	2.168e-143	463.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2VM19@28216|Betaproteobacteria	28216|Betaproteobacteria	E	fad dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
PYH1_k127_6444142_3	1217718.ALOU01000098_gene4274	2.927e-155	500.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2VN2I@28216|Betaproteobacteria,1K659@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Peptidase family M28	cgp	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
PYH1_k127_6444142_9	1532557.JL37_05170	9.382e-43	163.0	COG1545@1|root,COG1545@2|Bacteria,1N2C8@1224|Proteobacteria,2VR2X@28216|Betaproteobacteria,3T7MK@506|Alcaligenaceae	28216|Betaproteobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
PYH1_k127_6444142_2	381666.H16_B0591	6.255e-174	558.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2VNPV@28216|Betaproteobacteria,1K85Y@119060|Burkholderiaceae	28216|Betaproteobacteria	I	thiolase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
PYH1_k127_6444142_7	570967.JMLV01000011_gene3288	2.098e-78	282.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2JRJV@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
PYH1_k127_6494108_1	94624.Bpet4158	2.235e-87	292.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,3T6UJ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
PYH1_k127_6494108_0	795666.MW7_3397	3.464e-277	865.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VI6D@28216|Betaproteobacteria,1K5TM@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PYH1_k127_6494108_2	290397.Adeh_0745	0.0001668	44.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,43C6E@68525|delta/epsilon subdivisions,2WTIV@28221|Deltaproteobacteria,2YZ25@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_6553758_1	640081.Dsui_2702	2.822e-32	138.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria,2KW2J@206389|Rhodocyclales	206389|Rhodocyclales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	-	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
PYH1_k127_6553758_0	522306.CAP2UW1_3631	4.378e-140	458.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,1KQ8U@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
PYH1_k127_6580838_5	159450.NH14_17815	3.738e-150	483.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2VIZ7@28216|Betaproteobacteria,1K1XB@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
PYH1_k127_6580838_13	1283300.ATXB01000001_gene163	4.305e-42	161.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1XDMM@135618|Methylococcales	135618|Methylococcales	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
PYH1_k127_6580838_2	395019.Bmul_1788	5.657e-280	872.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,1K2GN@119060|Burkholderiaceae	28216|Betaproteobacteria	C	electron transfer flavoprotein-ubiquinone oxidoreductase	etf	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8
PYH1_k127_6580838_1	62928.azo2149	4.845e-284	888.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2VKAN@28216|Betaproteobacteria,2KVQH@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-coenzyme A synthetase N-terminus	acsA	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
PYH1_k127_6580838_16	1042877.GQS_00160	9.84e-14	82.0	COG1226@1|root,COG1357@1|root,arCOG03124@2157|Archaea,arCOG03127@2157|Archaea,2XWRE@28890|Euryarchaeota	28890|Euryarchaeota	P	low-complexity proteins	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Pentapeptide,Pentapeptide_4
PYH1_k127_6580838_12	543728.Vapar_4490	2.577e-65	233.0	COG1102@1|root,COG2823@1|root,COG1102@2|Bacteria,COG2823@2|Bacteria,1N42J@1224|Proteobacteria,2VK5B@28216|Betaproteobacteria,4AHC6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	BON,Cytidylate_kin2
PYH1_k127_6580838_0	1123487.KB892864_gene2082	1.403e-287	890.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,2KVHT@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
PYH1_k127_6580838_9	1163617.SCD_n01611	4.723e-128	441.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
PYH1_k127_6580838_4	1121472.AQWN01000005_gene2371	8.537e-168	550.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,2600A@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PYH1_k127_6580838_14	522306.CAP2UW1_3324	1.096e-28	117.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,1KR0J@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
PYH1_k127_6580838_15	1047013.AQSP01000111_gene1661	9.105e-15	83.0	COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria	2|Bacteria	O	peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
PYH1_k127_6580838_7	1121861.KB899915_gene1849	2.014e-135	437.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TUWV@28211|Alphaproteobacteria,2JQWC@204441|Rhodospirillales	204441|Rhodospirillales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH1_k127_6580838_8	1123392.AQWL01000003_gene468	8.122e-134	431.0	COG0625@1|root,COG0625@2|Bacteria,1Q5XX@1224|Proteobacteria,2WBJT@28216|Betaproteobacteria,1KS33@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
PYH1_k127_6580838_6	1380394.JADL01000012_gene843	5.833e-141	462.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria,2JW6K@204441|Rhodospirillales	204441|Rhodospirillales	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
PYH1_k127_6580838_10	864051.BurJ1DRAFT_2772	2.937e-119	388.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2VM24@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
PYH1_k127_6580838_3	1205680.CAKO01000040_gene670	2.022e-209	659.0	COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,2TRZ0@28211|Alphaproteobacteria,2JPX8@204441|Rhodospirillales	204441|Rhodospirillales	E	homoserine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,NAD_binding_3,SAF
PYH1_k127_6580838_11	1380394.JADL01000003_gene5125	3.051e-66	228.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2TTDW@28211|Alphaproteobacteria,2JRVY@204441|Rhodospirillales	204441|Rhodospirillales	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
PYH1_k127_6582292_3	1265502.KB905932_gene1869	3.012e-07	61.0	2A4J7@1|root,30APC@2|Bacteria,1QVHR@1224|Proteobacteria,2VX8G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	MJ0042 family finger-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_5
PYH1_k127_6582292_1	1454004.AW11_00082	1.822e-80	291.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,1KPX4@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
PYH1_k127_6582292_0	1000565.METUNv1_02081	3.352e-249	778.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,2KVNS@206389|Rhodocyclales	206389|Rhodocyclales	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
PYH1_k127_6582292_2	1231391.AMZF01000110_gene884	2.103e-38	144.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,3T3YH@506|Alcaligenaceae	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
PYH1_k127_6602924_7	582744.Msip34_0198	8.585e-08	54.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,2KMX4@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
PYH1_k127_6602924_6	1123367.C666_13375	4.933e-33	129.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,2KWVF@206389|Rhodocyclales	206389|Rhodocyclales	G	Phosphotransferase System	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PYH1_k127_6602924_0	1163617.SCD_n00085	4.576e-214	683.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
PYH1_k127_6602924_2	257310.BB4886	1.57e-159	511.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2VKB0@28216|Betaproteobacteria,3T2RR@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH1_k127_6602924_1	1123354.AUDR01000012_gene1800	1.598e-181	573.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metXS	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
PYH1_k127_6602924_4	580332.Slit_0035	2.728e-69	256.0	COG2890@1|root,COG2890@2|Bacteria,1R0WI@1224|Proteobacteria	1224|Proteobacteria	J	TIGRFAM methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
PYH1_k127_6602924_3	1454004.AW11_02632	4.354e-105	361.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VMKT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
PYH1_k127_6602924_5	267608.RSp0096	3.919e-40	159.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VM13@28216|Betaproteobacteria,1KH58@119060|Burkholderiaceae	28216|Betaproteobacteria	M	homology	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
PYH1_k127_6639876_9	743836.AYNA01000128_gene1396	2.506e-18	91.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria,370F4@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.156,4.2.1.42	ko:K20023	ko00053,map00053	-	R05608	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
PYH1_k127_6639876_1	1205680.CAKO01000002_gene2811	1.287e-125	419.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	MA20_07800	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
PYH1_k127_6639876_4	224911.27350935	1.246e-95	330.0	COG3485@1|root,COG3485@2|Bacteria,1MX7W@1224|Proteobacteria,2TT8T@28211|Alphaproteobacteria,3JRKQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	MA20_14295	-	1.13.11.37	ko:K04098	ko00361,ko00362,ko01100,ko01120,map00361,map00362,map01100,map01120	-	R03891,R04061	RC00388,RC01016	ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
PYH1_k127_6639876_3	1458275.AZ34_05950	7.513e-106	357.0	COG3181@1|root,COG3181@2|Bacteria,1N00G@1224|Proteobacteria,2VN46@28216|Betaproteobacteria,4ADS3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_6639876_5	414684.RC1_3398	1.077e-86	296.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2TSUU@28211|Alphaproteobacteria,2JPHD@204441|Rhodospirillales	204441|Rhodospirillales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
PYH1_k127_6639876_6	1192034.CAP_6087	9.521e-77	263.0	COG4312@1|root,COG4312@2|Bacteria,1QIBA@1224|Proteobacteria	1224|Proteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
PYH1_k127_6639876_2	1095769.CAHF01000023_gene511	7.048e-109	361.0	COG4313@1|root,COG4313@2|Bacteria,1R5Z9@1224|Proteobacteria,2VKTG@28216|Betaproteobacteria,477GC@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
PYH1_k127_6639876_7	398578.Daci_1998	1.776e-71	249.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,4ADTF@80864|Comamonadaceae	28216|Betaproteobacteria	S	SCO1/SenC	ypmQ_3	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
PYH1_k127_6639876_8	1131814.JAFO01000001_gene3376	3.088e-63	224.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TUKJ@28211|Alphaproteobacteria,3EZR6@335928|Xanthobacteraceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_6639876_0	864051.BurJ1DRAFT_2770	4.044e-232	730.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2W9GX@28216|Betaproteobacteria,1KNPZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
PYH1_k127_6651152_0	404589.Anae109_1032	1.899e-172	563.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
PYH1_k127_6686317_5	1379698.RBG1_1C00001G0380	1.778e-38	150.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
PYH1_k127_6686317_3	1267535.KB906767_gene998	8.539e-57	225.0	COG0265@1|root,COG2203@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07680	ko02020,ko02024,map02020,map02024	M00476	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	FHA,GAF,GAF_2,GAF_3,HAMP,HATPase_c_2,SpoIIE
PYH1_k127_6686317_6	1267533.KB906739_gene2500	9.958e-33	132.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,Response_reg
PYH1_k127_6686317_7	326427.Cagg_3036	4.461e-24	109.0	COG1366@1|root,COG1366@2|Bacteria,2G9K5@200795|Chloroflexi,375MW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS
PYH1_k127_6686317_0	1538295.JY96_08515	1.266e-155	512.0	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,2VPRW@28216|Betaproteobacteria,1KMBA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
PYH1_k127_6686317_4	706587.Desti_0365	2.965e-50	194.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cyaD	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Fer2,GAF,GAF_2,Guanylate_cyc,Pkinase,Response_reg
PYH1_k127_6686317_9	1120999.JONM01000012_gene2230	1.202e-05	57.0	COG4796@1|root,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria,2KSMW@206351|Neisseriales	206351|Neisseriales	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
PYH1_k127_6686317_8	1000565.METUNv1_00741	2.243e-08	65.0	2E5FR@1|root,3307F@2|Bacteria,1N89J@1224|Proteobacteria,2VVS4@28216|Betaproteobacteria,2KX8M@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6686317_2	292415.Tbd_1293	8.402e-59	206.0	COG4968@1|root,COG4968@2|Bacteria,1QW3U@1224|Proteobacteria	1224|Proteobacteria	U	general secretion pathway protein G	lspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
PYH1_k127_6686317_1	1123368.AUIS01000016_gene2552	5.727e-130	426.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,2NCMQ@225057|Acidithiobacillales	1236|Gammaproteobacteria	NU	PFAM type II secretion system	pilC	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
PYH1_k127_6689727_2	279714.FuraDRAFT_2697	3.327e-146	468.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,2KPZN@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
PYH1_k127_6689727_5	1123392.AQWL01000009_gene1104	4.319e-44	180.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,1KSFR@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
PYH1_k127_6689727_4	1121374.KB891576_gene724	4.815e-82	283.0	2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6689727_7	1121381.JNIV01000065_gene3724	4.091e-09	69.0	COG2202@1|root,COG3437@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3852@2|Bacteria,1WJ3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9
PYH1_k127_6689727_1	1304877.KI519399_gene2903	1.656e-168	540.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3JVBW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH1_k127_6689727_0	395495.Lcho_4221	5.566e-255	807.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VJ2Q@28216|Betaproteobacteria,1KKH9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_6689727_3	395495.Lcho_4220	6.243e-101	331.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VJ4X@28216|Betaproteobacteria,1KJ6E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_6689727_6	760117.JN27_15565	5.733e-10	59.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2VHEX@28216|Betaproteobacteria,472KJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_6692183_2	1217718.ALOU01000010_gene934	3.637e-35	134.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria,1K61J@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	hyfG	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
PYH1_k127_6692183_1	1163617.SCD_n02027	9.255e-81	275.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase 20 kDa subunit	hyfI	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
PYH1_k127_6692183_0	1123368.AUIS01000021_gene987	5.91e-129	428.0	COG0725@1|root,COG0725@2|Bacteria,1NACV@1224|Proteobacteria,1T2QW@1236|Gammaproteobacteria,2ND9P@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
PYH1_k127_6692183_3	292415.Tbd_0859	1.349e-15	87.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,2VVRU@28216|Betaproteobacteria,1KTEJ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
PYH1_k127_6704318_1	1123368.AUIS01000007_gene2819	2.5e-99	331.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,2NCEM@225057|Acidithiobacillales	1236|Gammaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
PYH1_k127_6704318_0	1095769.CAHF01000001_gene3561	7.535e-280	876.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,473Z4@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
PYH1_k127_6704318_2	748247.AZKH_1114	7.771e-98	324.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,2KUHR@206389|Rhodocyclales	206389|Rhodocyclales	C	glycolate oxidase iron-sulfur subunit	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
PYH1_k127_6715192_1	1134912.AJTV01000038_gene3330	3.805e-135	434.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,36Y2W@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.321	ko:K13688,ko:K18786	-	-	R10832	RC00397	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
PYH1_k127_6715192_0	1432055.GLUCORHAEAF1_04065	1.707e-232	736.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TQSC@28211|Alphaproteobacteria,2JREM@204441|Rhodospirillales	204441|Rhodospirillales	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PYH1_k127_6715192_4	748247.AZKH_3407	4.103e-17	81.0	COG4876@1|root,COG4876@2|Bacteria,1NJCS@1224|Proteobacteria,2VYBB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6715192_2	1120792.JAFV01000001_gene3701	1.335e-49	184.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VF0E@28211|Alphaproteobacteria,36YFG@31993|Methylocystaceae	28211|Alphaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	MA20_44950	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Rhodanese
PYH1_k127_6715192_3	264462.Bd1116	3.475e-19	90.0	COG2114@1|root,COG2770@1|root,COG2114@2|Bacteria,COG2770@2|Bacteria,1MV1V@1224|Proteobacteria,42SUQ@68525|delta/epsilon subdivisions,2MUNS@213481|Bdellovibrionales,2WPIY@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
PYH1_k127_6726966_2	1120977.JHUX01000003_gene1053	3.825e-35	136.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RQ5M@1236|Gammaproteobacteria,3NJXV@468|Moraxellaceae	1236|Gammaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_6726966_3	395495.Lcho_1836	7.673e-33	137.0	COG2050@1|root,COG2050@2|Bacteria,1N5HF@1224|Proteobacteria,2VQ8W@28216|Betaproteobacteria,1KM7Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH1_k127_6726966_0	1123504.JQKD01000002_gene3681	1.87e-140	469.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,4ACGH@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_6726966_1	543728.Vapar_4936	2.005e-122	397.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,4A9UR@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
PYH1_k127_6737389_3	1163617.SCD_n01666	7.096e-242	765.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
PYH1_k127_6737389_11	381666.H16_A2752	1.379e-115	398.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,1K05P@119060|Burkholderiaceae	28216|Betaproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
PYH1_k127_6737389_24	388051.AUFE01000028_gene5052	8.496e-58	218.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,1KFT4@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
PYH1_k127_6737389_16	640081.Dsui_2698	5.348e-103	342.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,2KV4J@206389|Rhodocyclales	206389|Rhodocyclales	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
PYH1_k127_6737389_20	1122604.JONR01000010_gene3902	3.073e-75	268.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,1S2DI@1236|Gammaproteobacteria,1XBZM@135614|Xanthomonadales	135614|Xanthomonadales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
PYH1_k127_6737389_1	1000565.METUNv1_01302	8.2e-321	1003.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,2KV4M@206389|Rhodocyclales	206389|Rhodocyclales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
PYH1_k127_6737389_6	323848.Nmul_A2632	2.528e-135	434.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,371P4@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Methionine aminopeptidase	map	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
PYH1_k127_6737389_9	323848.Nmul_A0657	1.144e-120	393.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,371SG@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
PYH1_k127_6737389_17	1163617.SCD_n01634	1.043e-97	329.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
PYH1_k127_6737389_10	1163617.SCD_n01633	8.444e-116	377.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PYH1_k127_6737389_19	1000565.METUNv1_01297	1.381e-75	269.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,2KV5P@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
PYH1_k127_6737389_15	402626.Rpic_1282	7.422e-106	349.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,1K0E6@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
PYH1_k127_6737389_27	1121035.AUCH01000017_gene2305	3.928e-45	183.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,2KW5H@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
PYH1_k127_6737389_5	76114.ebA5994	2.063e-142	475.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,2KVYE@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
PYH1_k127_6737389_4	323848.Nmul_A0664	3.955e-148	482.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,371TQ@32003|Nitrosomonadales	28216|Betaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
PYH1_k127_6737389_2	1163617.SCD_n01627	8.768e-296	925.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
PYH1_k127_6737389_25	305700.B447_05273	4.671e-55	198.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria,2KWH8@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the skp family	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
PYH1_k127_6737389_12	1485544.JQKP01000007_gene1941	1.625e-114	379.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,44V3V@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
PYH1_k127_6737389_23	748247.AZKH_2389	2.02e-59	211.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,2KWAJ@206389|Rhodocyclales	206389|Rhodocyclales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
PYH1_k127_6737389_14	748247.AZKH_2390	1.092e-107	361.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,2KV6X@206389|Rhodocyclales	206389|Rhodocyclales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
PYH1_k127_6737389_8	640081.Dsui_2681	8.439e-123	418.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,2KUHP@206389|Rhodocyclales	206389|Rhodocyclales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
PYH1_k127_6737389_22	1123367.C666_02535	7.271e-63	225.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,2KW1V@206389|Rhodocyclales	206389|Rhodocyclales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
PYH1_k127_6737389_18	760117.JN27_20190	2.943e-78	274.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria,475P7@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
PYH1_k127_6737389_7	404589.Anae109_0564	4.633e-126	415.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria	1224|Proteobacteria	H	Methyl-transferase	egtB	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
PYH1_k127_6737389_26	76114.ebA6008	3.223e-51	191.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,2KW4N@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
PYH1_k127_6737389_13	640081.Dsui_2678	2.706e-110	362.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,2KVFV@206389|Rhodocyclales	206389|Rhodocyclales	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
PYH1_k127_6737389_0	1500894.JQNN01000001_gene1623	0.0	1115.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VHQ3@28216|Betaproteobacteria,4736M@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
PYH1_k127_6737389_21	323848.Nmul_A1203	1.955e-66	229.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,37321@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
PYH1_k127_6737389_28	1005048.CFU_1355	9.867e-38	146.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,47453@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Oligoketide cyclase lipid transport protein	ratA	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
PYH1_k127_6737389_29	1123261.AXDW01000004_gene2833	1.032e-06	53.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1X84S@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the UPF0125 (RnfH) family	-	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
PYH1_k127_6739254_0	215803.DB30_0294	3.071e-45	180.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2X5DN@28221|Deltaproteobacteria,2YUJ5@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
PYH1_k127_6743756_7	1205680.CAKO01000040_gene818	4.62e-08	64.0	COG2242@1|root,COG2242@2|Bacteria,1QX6B@1224|Proteobacteria,2TZAR@28211|Alphaproteobacteria,2JUEP@204441|Rhodospirillales	204441|Rhodospirillales	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
PYH1_k127_6743756_5	864702.OsccyDRAFT_3649	6.237e-55	201.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	2.1.1.187,2.1.1.235,2.1.1.324	ko:K00563,ko:K13307,ko:K13330,ko:K15256	ko00523,ko01130,map00523,map01130	M00796,M00802	R06439,R07233,R08932,R11452,R11453	RC00003,RC01515,RC02262,RC03440	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
PYH1_k127_6743756_1	240015.ACP_0749	6.641e-151	505.0	COG0451@1|root,COG0451@2|Bacteria,3Y3J3@57723|Acidobacteria,2JIFZ@204432|Acidobacteriia	204432|Acidobacteriia	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
PYH1_k127_6743756_0	1205680.CAKO01000010_gene4002	1.33e-158	511.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2JPVB@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
PYH1_k127_6743756_2	196490.AUEZ01000050_gene363	7.575e-77	276.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,2TU3M@28211|Alphaproteobacteria,3JQWF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	GM	ABC transporter	rfbE	-	-	ko:K01990,ko:K09691	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC_tran
PYH1_k127_6743756_3	640510.BC1001_0658	8.656e-76	263.0	COG1682@1|root,COG1682@2|Bacteria,1MWG4@1224|Proteobacteria,2VRW8@28216|Betaproteobacteria	28216|Betaproteobacteria	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
PYH1_k127_6743756_4	1123392.AQWL01000001_gene1560	4.434e-57	207.0	COG1216@1|root,COG1216@2|Bacteria,1NG6M@1224|Proteobacteria,2VQVQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_transf_21,Glyco_transf_7C,Glycos_transf_2
PYH1_k127_6743756_6	946483.Cenrod_1767	1.275e-42	162.0	COG0463@1|root,COG0463@2|Bacteria,1N635@1224|Proteobacteria,2VWIY@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PYH1_k127_6745404_4	76114.ebA2062	2.542e-72	249.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2WGS8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
PYH1_k127_6745404_0	76114.ebA2060	1.276e-270	847.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,2KV3E@206389|Rhodocyclales	28216|Betaproteobacteria	I	Methylmalonyl-CoA mutase	icmF	-	5.4.99.2,5.4.99.63,5.4.99.64	ko:K01847,ko:K01848,ko:K14447,ko:K20906	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833,R09292	RC00395,RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
PYH1_k127_6745404_5	76114.ebD52	9.068e-54	209.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,2VW7W@28216|Betaproteobacteria	28216|Betaproteobacteria	I	B12 binding domain	-	-	5.4.99.2,5.4.99.64	ko:K01849,ko:K20907	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
PYH1_k127_6745404_2	76114.ebA2055	8.777e-188	598.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,2KVJQ@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_6745404_3	1244869.H261_12236	4.722e-155	505.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JPCT@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_6745404_1	316055.RPE_3219	6.944e-197	622.0	COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,2TUBT@28211|Alphaproteobacteria,3K2FJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
PYH1_k127_6745404_6	316055.RPE_3220	1.593e-17	83.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,2TUKM@28211|Alphaproteobacteria,3JUR2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	GntR family	MA20_10290	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH1_k127_674926_5	1123504.JQKD01000005_gene4741	1.836e-61	219.0	COG2230@1|root,COG2230@2|Bacteria,1QX5S@1224|Proteobacteria,2WHKW@28216|Betaproteobacteria,4AJZM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
PYH1_k127_674926_1	1038859.AXAU01000015_gene937	1.252e-218	688.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVRF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
PYH1_k127_674926_3	1038859.AXAU01000015_gene935	1.804e-133	432.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2UR9F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_674926_0	1454004.AW11_02472	5.036e-237	751.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJ5E@28216|Betaproteobacteria,1KQBH@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	AMP-binding enzyme	bclA_2	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_674926_6	296591.Bpro_0530	3.601e-52	209.0	COG1011@1|root,COG1011@2|Bacteria,1QEJI@1224|Proteobacteria,2W9ZX@28216|Betaproteobacteria,4AIJD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
PYH1_k127_674926_4	748247.AZKH_3278	5.699e-80	273.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,2KW7A@206389|Rhodocyclales	206389|Rhodocyclales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
PYH1_k127_674926_2	522306.CAP2UW1_0261	1.136e-208	654.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,1KQI7@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
PYH1_k127_6784434_3	76114.ebA122	6.233e-63	231.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,2KVHZ@206389|Rhodocyclales	206389|Rhodocyclales	C	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4_10,POR_N,TPP_enzyme_C
PYH1_k127_6784434_4	243365.CV_0968	5.202e-60	211.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2WFK8@28216|Betaproteobacteria,2KQZY@206351|Neisseriales	206351|Neisseriales	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
PYH1_k127_6784434_0	595537.Varpa_1641	9.54e-150	489.0	COG0240@1|root,COG0240@2|Bacteria,1MXI9@1224|Proteobacteria,2VW0B@28216|Betaproteobacteria,4AJYR@80864|Comamonadaceae	28216|Betaproteobacteria	C	NAD NADP octopine nopaline dehydrogenase	-	-	1.5.1.28	ko:K04940	-	-	-	-	ko00000,ko01000	-	-	-	ApbA,NAD_Gly3P_dh_N,Octopine_DH
PYH1_k127_6784434_2	391937.NA2_14487	1.923e-104	359.0	COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria,43MMU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
PYH1_k127_6784434_1	1231391.AMZF01000022_gene1262	5.971e-130	426.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2W9BE@28216|Betaproteobacteria,3T5JA@506|Alcaligenaceae	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_6784434_5	522306.CAP2UW1_4467	1.873e-26	110.0	COG0559@1|root,COG0559@2|Bacteria,1MXMC@1224|Proteobacteria,2VJ1Y@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_6786507_2	225849.swp_4082	2.421e-13	81.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,2Q9UJ@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM Nucleotidyl transferase	-	GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.7.13,2.7.7.99	ko:K00966,ko:K00992	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
PYH1_k127_6786507_1	265072.Mfla_2148	6.567e-134	434.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,2KM5S@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
PYH1_k127_6786507_0	640081.Dsui_1587	7.444e-172	565.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,2KVBE@206389|Rhodocyclales	206389|Rhodocyclales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
PYH1_k127_6805620_0	1163617.SCD_n02625	1.532e-100	345.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria	28216|Betaproteobacteria	H	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
PYH1_k127_6830699_4	1286631.X805_22830	8.248e-15	75.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,1KMGT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
PYH1_k127_6830699_5	314278.NB231_00325	2.914e-14	86.0	COG0589@1|root,COG0589@2|Bacteria,1N8R6@1224|Proteobacteria,1SFRC@1236|Gammaproteobacteria,1X2PS@135613|Chromatiales	135613|Chromatiales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6830699_0	338969.Rfer_0831	3.507e-263	835.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria,4ACBR@80864|Comamonadaceae	28216|Betaproteobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
PYH1_k127_6830699_1	472759.Nhal_1481	2.447e-175	560.0	COG2403@1|root,COG2403@2|Bacteria,1MV4C@1224|Proteobacteria	1224|Proteobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6830699_2	1123354.AUDR01000015_gene351	4.816e-53	194.0	COG1371@1|root,COG1371@2|Bacteria	2|Bacteria	J	PFAM Archease protein family (DUF101 UPF0211)	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease
PYH1_k127_6830699_3	713587.THITH_07530	3.078e-38	149.0	COG2267@1|root,COG2267@2|Bacteria,1N2KV@1224|Proteobacteria	1224|Proteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_688893_2	864051.BurJ1DRAFT_0770	5.064e-129	427.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2VICE@28216|Betaproteobacteria,1KN7G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
PYH1_k127_688893_0	472759.Nhal_3170	3.522e-167	536.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
PYH1_k127_688893_1	1120999.JONM01000003_gene2732	1.776e-146	484.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,2KR1E@206351|Neisseriales	206351|Neisseriales	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
PYH1_k127_688893_3	762376.AXYL_01152	4.897e-16	83.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,2VRZJ@28216|Betaproteobacteria,3T7T0@506|Alcaligenaceae	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH1_k127_6893773_1	323848.Nmul_A2416	7.373e-34	139.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,2WGEF@28216|Betaproteobacteria,3729Q@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhosphMutase
PYH1_k127_6893773_0	391038.Bphy_1448	9.746e-132	440.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,1K24G@119060|Burkholderiaceae	28216|Betaproteobacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
PYH1_k127_6894821_2	164757.Mjls_4433	1.19e-34	148.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH1_k127_6894821_3	1000565.METUNv1_02004	1.184e-21	108.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,2VWEG@28216|Betaproteobacteria,2KZ8A@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
PYH1_k127_6894821_4	1380394.JADL01000004_gene6098	3.198e-15	91.0	2DM5E@1|root,31SVN@2|Bacteria,1MYKR@1224|Proteobacteria,2U9KT@28211|Alphaproteobacteria,2JSXH@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
PYH1_k127_6894821_0	1123072.AUDH01000014_gene1303	1.111e-99	348.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,2U1SX@28211|Alphaproteobacteria,2JRJ2@204441|Rhodospirillales	204441|Rhodospirillales	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
PYH1_k127_6894821_1	1123073.KB899242_gene1477	5.175e-86	293.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
PYH1_k127_6903896_0	1002809.SSIL_2408	1.189e-223	708.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,26DUZ@186818|Planococcaceae	91061|Bacilli	E	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_6903896_1	316055.RPE_3198	4.75e-125	433.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,2U2YW@28211|Alphaproteobacteria,3JYK9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
PYH1_k127_6903896_2	358220.C380_17780	1.56e-113	376.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,2VZMU@28216|Betaproteobacteria,4AGC6@80864|Comamonadaceae	28216|Betaproteobacteria	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
PYH1_k127_6903896_3	439235.Dalk_1399	4.802e-56	203.0	COG4221@1|root,COG4221@2|Bacteria,1R08W@1224|Proteobacteria,43CRM@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH1_k127_691955_2	1100721.ALKO01000017_gene1789	1.185e-29	123.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2W19X@28216|Betaproteobacteria,4ABCC@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_691955_0	864051.BurJ1DRAFT_1140	6.999e-149	484.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria,1KKHF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_691955_1	1121033.AUCF01000005_gene5323	7.144e-135	435.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2TT4V@28211|Alphaproteobacteria,2JPUT@204441|Rhodospirillales	204441|Rhodospirillales	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
PYH1_k127_6936477_3	1223521.BBJX01000001_gene997	1.195e-67	232.0	COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2VH1W@28216|Betaproteobacteria,4ACN8@80864|Comamonadaceae	28216|Betaproteobacteria	S	cytochrome d1 heme region	nirF	-	-	ko:K19345	-	-	-	-	ko00000	-	-	-	Cytochrom_D1
PYH1_k127_6936477_1	159087.Daro_3269	2.075e-97	335.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,2VHP8@28216|Betaproteobacteria,2KUR4@206389|Rhodocyclales	206389|Rhodocyclales	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_6936477_5	686340.Metal_2271	5.921e-48	179.0	COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,1S8HH@1236|Gammaproteobacteria,1XF8H@135618|Methylococcales	135618|Methylococcales	K	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
PYH1_k127_6936477_4	1238182.C882_1455	4.816e-55	203.0	COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,2U84D@28211|Alphaproteobacteria,2JSN9@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
PYH1_k127_6936477_0	640081.Dsui_3126	1.036e-193	609.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VJD9@28216|Betaproteobacteria,2KUGV@206389|Rhodocyclales	206389|Rhodocyclales	C	radical SAM protein	nirJ	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
PYH1_k127_6936477_2	204773.HEAR1684	4.511e-83	283.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,4747S@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	dnrD	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH1_k127_6936477_6	1121035.AUCH01000025_gene3337	5.351e-34	138.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,2KW83@206389|Rhodocyclales	206389|Rhodocyclales	O	Cytochrome c-type biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16
PYH1_k127_694022_11	338969.Rfer_2742	2.298e-73	257.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,2VP9Y@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
PYH1_k127_694022_9	365046.Rta_09180	1.107e-75	258.0	COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,2WFRW@28216|Betaproteobacteria,4ADQJ@80864|Comamonadaceae	28216|Betaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
PYH1_k127_694022_5	748247.AZKH_4514	2.841e-226	711.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,2KY7V@206389|Rhodocyclales	206389|Rhodocyclales	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_694022_16	1380394.JADL01000003_gene5180	1.112e-50	184.0	COG0369@1|root,COG0369@2|Bacteria,1QUX0@1224|Proteobacteria,2U85Q@28211|Alphaproteobacteria,2JXR2@204441|Rhodospirillales	204441|Rhodospirillales	P	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
PYH1_k127_694022_13	266264.Rmet_1223	5.831e-65	231.0	COG0703@1|root,COG1396@1|root,COG0703@2|Bacteria,COG1396@2|Bacteria,1MX66@1224|Proteobacteria,2VK91@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	bzdR	-	-	ko:K15546	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31,SKI
PYH1_k127_694022_2	388051.AUFE01000023_gene4556	1.607e-247	788.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,2VKSK@28216|Betaproteobacteria	28216|Betaproteobacteria	I	enoyl-CoA hydratase	boxC	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
PYH1_k127_694022_1	62928.azo3057	4.781e-266	827.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2VH89@28216|Betaproteobacteria,2KVI4@206389|Rhodocyclales	206389|Rhodocyclales	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
PYH1_k127_694022_4	1380394.JADL01000003_gene5164	3.02e-242	757.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2TTIG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
PYH1_k127_694022_14	85643.Tmz1t_0478	7.603e-54	199.0	COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,2VT5X@28216|Betaproteobacteria,2KWJT@206389|Rhodocyclales	206389|Rhodocyclales	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PYH1_k127_694022_0	381666.H16_B0315	9.384e-272	846.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNB8@28216|Betaproteobacteria,1KGH9@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
PYH1_k127_694022_3	62928.azo1350	1.304e-243	765.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VKMW@28216|Betaproteobacteria,2KV2G@206389|Rhodocyclales	206389|Rhodocyclales	I	Poly-beta-hydroxybutyrate	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
PYH1_k127_694022_12	296591.Bpro_0196	2.318e-65	236.0	COG0697@1|root,COG0697@2|Bacteria,1MY34@1224|Proteobacteria,2VJYT@28216|Betaproteobacteria,4A9ZH@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_694022_10	1116375.VEJY3_20461	5.334e-74	258.0	COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,1S0F8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cysteine dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
PYH1_k127_694022_19	1207063.P24_08394	2.697e-24	109.0	COG3915@1|root,COG3915@2|Bacteria,1N2TM@1224|Proteobacteria,2UE89@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
PYH1_k127_694022_18	1121035.AUCH01000013_gene3085	1.768e-38	148.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,2KW8T@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH1_k127_694022_7	571166.KI421509_gene1920	3.285e-144	469.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
PYH1_k127_694022_8	1245469.S58_61710	4.905e-136	443.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2U4YK@28211|Alphaproteobacteria,3JT2R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	alpha/beta hydrolase fold	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
PYH1_k127_694022_6	1298867.AUES01000001_gene1680	7.529e-149	480.0	COG2267@1|root,COG2267@2|Bacteria,1MV7P@1224|Proteobacteria,2TSQ8@28211|Alphaproteobacteria,3JSCA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
PYH1_k127_694022_17	1037409.BJ6T_87360	5.081e-40	161.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_694022_15	189753.AXAS01000041_gene2534	1.747e-53	201.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_694022_20	234267.Acid_3867	1.632e-17	83.0	COG4274@1|root,COG4274@2|Bacteria,3Y87J@57723|Acidobacteria	57723|Acidobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
PYH1_k127_6950664_1	55601.VANGNB10_cI1158	2.557e-16	82.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1XSKM@135623|Vibrionales	135623|Vibrionales	EGP	of the major facilitator superfamily	bcr	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
PYH1_k127_6950664_0	471852.Tcur_1518	2.796e-234	733.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria,4EMF2@85012|Streptosporangiales	201174|Actinobacteria	EQ	Hydantoinase B/oxoprolinase	oplA	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0266c	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
PYH1_k127_698276_2	1403819.BATR01000195_gene6595	1.014e-138	461.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PYH1_k127_698276_3	338966.Ppro_0405	1.002e-85	301.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42S7F@68525|delta/epsilon subdivisions,2WK0P@28221|Deltaproteobacteria,43T7X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
PYH1_k127_698276_7	404589.Anae109_1726	1.849e-24	109.0	COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria	1224|Proteobacteria	G	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH1_k127_698276_5	1323663.AROI01000011_gene3243	1.143e-56	203.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP	acpH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576	3.1.4.14	ko:K08682	ko00770,map00770	-	R01623	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426	ACP_PD
PYH1_k127_698276_0	287.DR97_3544	2.627e-201	670.0	COG0834@1|root,COG2202@1|root,COG5001@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YE8V@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3
PYH1_k127_698276_4	331869.BAL199_09700	2.574e-82	299.0	COG5285@1|root,COG5285@2|Bacteria,1R84J@1224|Proteobacteria	1224|Proteobacteria	Q	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
PYH1_k127_698276_6	1244869.H261_01462	1.253e-50	203.0	COG0265@1|root,COG0790@1|root,COG0265@2|Bacteria,COG0790@2|Bacteria,1MV63@1224|Proteobacteria,2TS54@28211|Alphaproteobacteria,2JSRF@204441|Rhodospirillales	204441|Rhodospirillales	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sel1,Trypsin_2
PYH1_k127_698276_1	1380394.JADL01000007_gene4450	6.806e-193	616.0	COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria,2JYB7@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
PYH1_k127_6990259_2	1000565.METUNv1_00162	1.164e-19	101.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,2KX79@206389|Rhodocyclales	206389|Rhodocyclales	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
PYH1_k127_6990259_1	1000565.METUNv1_00163	3.814e-150	482.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,2KUZJ@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
PYH1_k127_6990259_0	76114.ebA977	1.424e-164	528.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,2KVC4@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
PYH1_k127_7003139_6	338966.Ppro_1346	0.0003079	53.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2WRNN@28221|Deltaproteobacteria,43TA8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
PYH1_k127_7003139_3	497321.C664_10987	5.442e-145	471.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,2KV2R@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC1	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH1_k127_7003139_4	305700.B447_01101	2.324e-115	397.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,2KUSW@206389|Rhodocyclales	206389|Rhodocyclales	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
PYH1_k127_7003139_1	864051.BurJ1DRAFT_2067	7.761e-166	530.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,1KMB7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH1_k127_7003139_2	1123368.AUIS01000020_gene1092	1.821e-161	517.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,2NCS3@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
PYH1_k127_7003139_0	748247.AZKH_3560	0.0	1310.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,2KV41@206389|Rhodocyclales	206389|Rhodocyclales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
PYH1_k127_7003139_5	323848.Nmul_A2188	4.938e-10	63.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,371W8@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
PYH1_k127_7003264_2	640081.Dsui_0586	4.177e-147	475.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria,2KUH1@206389|Rhodocyclales	206389|Rhodocyclales	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7003264_4	1123393.KB891316_gene1900	1.122e-113	374.0	COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria,2WA3C@28216|Betaproteobacteria,1KRW5@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
PYH1_k127_7003264_6	522306.CAP2UW1_4082	4.046e-89	301.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-3 protein	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
PYH1_k127_7003264_12	1000565.METUNv1_02937	8.645e-54	203.0	COG1366@1|root,COG1366@2|Bacteria,1R08G@1224|Proteobacteria,2VIGK@28216|Betaproteobacteria,2KVYW@206389|Rhodocyclales	206389|Rhodocyclales	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
PYH1_k127_7003264_7	1000565.METUNv1_02936	3.338e-86	289.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2VIFV@28216|Betaproteobacteria,2KUW6@206389|Rhodocyclales	206389|Rhodocyclales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
PYH1_k127_7003264_0	1121035.AUCH01000008_gene1116	2.918e-205	649.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,2KVM8@206389|Rhodocyclales	206389|Rhodocyclales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
PYH1_k127_7003264_11	1198452.Jab_1c03280	3.642e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,474SQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PYH1_k127_7003264_13	1454004.AW11_00331	4.986e-40	153.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
PYH1_k127_7003264_3	1131553.JIBI01000002_gene1824	4.701e-139	447.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,3729E@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
PYH1_k127_7003264_8	1304883.KI912532_gene1430	1.317e-74	258.0	COG0637@1|root,COG0637@2|Bacteria,1QTWD@1224|Proteobacteria,2VNTW@28216|Betaproteobacteria,2KW3U@206389|Rhodocyclales	206389|Rhodocyclales	S	Pyrimidine 5''-nucleotidase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
PYH1_k127_7003264_9	760117.JN27_22400	3.411e-59	210.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,473XV@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
PYH1_k127_7003264_5	640081.Dsui_1268	2.401e-104	344.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,2KUF5@206389|Rhodocyclales	206389|Rhodocyclales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
PYH1_k127_7003264_1	497321.C664_17642	3.578e-197	624.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,2KUHV@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
PYH1_k127_7003264_10	1266925.JHVX01000013_gene1642	3.77e-55	198.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,371NY@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
PYH1_k127_7018061_3	1384056.N787_04435	1.034e-60	216.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RVZ6@1236|Gammaproteobacteria,1XCIP@135614|Xanthomonadales	135614|Xanthomonadales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	-	-	-	-	-	-	-	-	-	-	SUA5,Sua5_yciO_yrdC
PYH1_k127_7018061_1	1123060.JONP01000011_gene3108	1.775e-163	529.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2TS7J@28211|Alphaproteobacteria,2JQWQ@204441|Rhodospirillales	204441|Rhodospirillales	P	PhoD-like phosphatase, N-terminal domain	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
PYH1_k127_7018061_5	543913.D521_1332	1.447e-41	154.0	COG2721@1|root,COG2721@2|Bacteria,1MZBN@1224|Proteobacteria,2VU0R@28216|Betaproteobacteria	28216|Betaproteobacteria	G	SAF	-	-	4.4.1.24	ko:K16845	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	SAF
PYH1_k127_7018061_0	1159870.KB907784_gene1703	6.077e-213	670.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VK3Y@28216|Betaproteobacteria,3T6WH@506|Alcaligenaceae	28216|Betaproteobacteria	G	D-galactarate dehydratase	-	-	4.2.1.7,4.4.1.24	ko:K16846,ko:K16850	ko00040,ko00270,ko01100,map00040,map00270,map01100	M00631	R01540,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
PYH1_k127_7018061_4	94624.Bpet0399	1.327e-60	233.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VJ4K@28216|Betaproteobacteria,3T25K@506|Alcaligenaceae	28216|Betaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
PYH1_k127_7018061_2	330214.NIDE0836	1.234e-123	419.0	COG1048@1|root,COG1048@2|Bacteria,3J0E6@40117|Nitrospirae	40117|Nitrospirae	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
PYH1_k127_7024712_0	1000565.METUNv1_00142	3.736e-186	588.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,2KVME@206389|Rhodocyclales	206389|Rhodocyclales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
PYH1_k127_7024712_1	522306.CAP2UW1_0573	1.932e-78	287.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,1KPNA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
PYH1_k127_7046291_0	1123367.C666_12150	2.293e-131	426.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,2KUDI@206389|Rhodocyclales	206389|Rhodocyclales	CM	Acyl-CoA synthetase (NDP forming)	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
PYH1_k127_7075331_0	864051.BurJ1DRAFT_0810	1.812e-206	646.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,1KJ4C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
PYH1_k127_7075331_1	381666.H16_A1588	2.817e-165	537.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,2VNV5@28216|Betaproteobacteria,1KH21@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Substrate binding domain of ABC-type glycine betaine transport system	opuBC	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
PYH1_k127_7075331_2	1000565.METUNv1_03029	7.016e-25	105.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,2KUI4@206389|Rhodocyclales	206389|Rhodocyclales	P	COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PYH1_k127_7084240_3	1331060.RLDS_09375	4.006e-95	323.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	MA20_07800	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
PYH1_k127_7084240_6	1173264.KI913949_gene1162	3.392e-72	252.0	COG2818@1|root,COG2818@2|Bacteria,1G5Y1@1117|Cyanobacteria	1117|Cyanobacteria	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
PYH1_k127_7084240_7	643562.Daes_2166	5.111e-69	241.0	COG1028@1|root,COG1028@2|Bacteria,1R5DB@1224|Proteobacteria,435R3@68525|delta/epsilon subdivisions,2X05M@28221|Deltaproteobacteria,2MAPH@213115|Desulfovibrionales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH1_k127_7084240_13	1205680.CAKO01000004_gene3634	1.039e-09	66.0	COG0824@1|root,COG0824@2|Bacteria,1RKPX@1224|Proteobacteria,2VA5C@28211|Alphaproteobacteria,2JUWJ@204441|Rhodospirillales	204441|Rhodospirillales	S	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
PYH1_k127_7084240_0	1217718.ALOU01000031_gene1578	2.836e-210	704.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VJEX@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
PYH1_k127_7084240_10	1217718.ALOU01000031_gene1577	4.05e-29	124.0	COG4726@1|root,COG4726@2|Bacteria,1N7I4@1224|Proteobacteria,2VVZB@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
PYH1_k127_7084240_8	1217718.ALOU01000031_gene1576	2.871e-66	238.0	COG4966@1|root,COG4966@2|Bacteria,1RC4Q@1224|Proteobacteria,2VS7N@28216|Betaproteobacteria,1K54M@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	type 4 fimbrial biogenesis	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
PYH1_k127_7084240_9	1217718.ALOU01000031_gene1575	8.972e-40	157.0	COG4967@1|root,COG4967@2|Bacteria,1N7MW@1224|Proteobacteria,2WGD7@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
PYH1_k127_7084240_12	1217718.ALOU01000031_gene1574	1.058e-24	111.0	COG4970@1|root,COG4970@2|Bacteria,1N0DB@1224|Proteobacteria,2VU1S@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
PYH1_k127_7084240_11	543728.Vapar_2839	1.106e-25	112.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,2VUU4@28216|Betaproteobacteria,4AFPB@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
PYH1_k127_7084240_4	288000.BBta_6680	7.854e-91	315.0	COG1804@1|root,COG1804@2|Bacteria,1MWPB@1224|Proteobacteria,2U1YE@28211|Alphaproteobacteria,3JS2K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	MA20_04610	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
PYH1_k127_7084240_2	1121920.AUAU01000005_gene1045	3.129e-122	400.0	COG0329@1|root,COG0329@2|Bacteria,3Y8R8@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
PYH1_k127_7084240_1	1100720.ALKN01000035_gene981	3.112e-137	459.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_7084240_5	1392838.AWNM01000080_gene2680	5.614e-88	306.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2W0CR@28216|Betaproteobacteria,3T6NS@506|Alcaligenaceae	28216|Betaproteobacteria	C	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
PYH1_k127_711184_10	1380394.JADL01000007_gene4512	2.906e-93	309.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,2JQV0@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
PYH1_k127_711184_15	667632.KB890172_gene4005	2.874e-41	166.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,1K7HX@119060|Burkholderiaceae	28216|Betaproteobacteria	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
PYH1_k127_711184_8	1348657.M622_17920	1.9e-112	376.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,2KVEJ@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS_8
PYH1_k127_711184_9	557598.LHK_00165	1.065e-97	323.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,2KQ47@206351|Neisseriales	206351|Neisseriales	T	Transcriptional regulatory protein, C terminal	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH1_k127_711184_11	323848.Nmul_A0435	2.66e-80	286.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,371Y8@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
PYH1_k127_711184_6	1538295.JY96_01320	1.35e-124	420.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KK41@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
PYH1_k127_711184_7	1437824.BN940_04486	1.13e-122	415.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,3T1E5@506|Alcaligenaceae	28216|Betaproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
PYH1_k127_711184_5	1216976.AX27061_4784	2.361e-134	435.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,3T2SF@506|Alcaligenaceae	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
PYH1_k127_711184_4	1163617.SCD_n00932	3.216e-145	467.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
PYH1_k127_711184_3	62928.azo2354	1.34e-166	532.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,2KUSU@206389|Rhodocyclales	206389|Rhodocyclales	P	COG0798 Arsenite efflux pump ACR3 and related permeases	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
PYH1_k127_711184_2	864051.BurJ1DRAFT_3225	2.767e-191	621.0	COG1600@1|root,COG1600@2|Bacteria,1QZV5@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	Dehalogenase
PYH1_k127_711184_13	1123368.AUIS01000019_gene1233	9.513e-59	213.0	COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,1S9JK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF3530
PYH1_k127_711184_1	1144319.PMI16_00452	3.989e-263	837.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
PYH1_k127_711184_12	196367.JNFG01000026_gene8203	1.54e-69	239.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ9M@28216|Betaproteobacteria,1K17P@119060|Burkholderiaceae	28216|Betaproteobacteria	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PYH1_k127_711184_14	1408164.MOLA814_01685	3.459e-57	213.0	COG0834@1|root,COG0834@2|Bacteria,1PC62@1224|Proteobacteria,2VY20@28216|Betaproteobacteria	28216|Betaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
PYH1_k127_711184_16	1408164.MOLA814_01686	3.515e-24	107.0	COG2010@1|root,COG2010@2|Bacteria,1RDPD@1224|Proteobacteria,2VYFE@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH1_k127_711184_0	1408164.MOLA814_01687	2.872e-296	917.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
PYH1_k127_711184_17	75379.Tint_0777	6.677e-07	52.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,1KJGK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH1_k127_715741_1	1485544.JQKP01000002_gene1623	4.493e-116	396.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,44V42@713636|Nitrosomonadales	28216|Betaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
PYH1_k127_715741_0	1163617.SCD_n02483	6.424e-119	391.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria	28216|Betaproteobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
PYH1_k127_715741_2	1121035.AUCH01000009_gene909	3.135e-14	73.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,2KVFZ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PYH1_k127_7209002_2	640081.Dsui_3134	8.844e-121	395.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,2KUAU@206389|Rhodocyclales	206389|Rhodocyclales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
PYH1_k127_7209002_3	1288494.EBAPG3_4010	1.522e-18	86.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,373MZ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
PYH1_k127_7209002_1	62928.azo0937	2.958e-121	399.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,2KUII@206389|Rhodocyclales	206389|Rhodocyclales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
PYH1_k127_7209002_0	292415.Tbd_0607	2.755e-215	688.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,1KRBE@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
PYH1_k127_7238971_1	246200.SPOA0174	1.267e-43	179.0	COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,2U0TX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
PYH1_k127_7238971_0	903818.KI912268_gene3392	4.292e-153	493.0	COG0513@1|root,COG0513@2|Bacteria,3Y2M6@57723|Acidobacteria	57723|Acidobacteria	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
PYH1_k127_7257138_1	90814.KL370891_gene747	0.0001534	49.0	2BZMS@1|root,32Z9B@2|Bacteria,1NCFD@1224|Proteobacteria,1SPFN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
PYH1_k127_7257138_0	439235.Dalk_1878	5.456e-124	415.0	COG2230@1|root,COG4797@1|root,COG2230@2|Bacteria,COG4797@2|Bacteria,1QU8H@1224|Proteobacteria,42NYA@68525|delta/epsilon subdivisions,2WT6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Predicted methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_25
PYH1_k127_7261664_7	305700.B447_06040	3.484e-35	143.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,2KW5V@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
PYH1_k127_7261664_9	323848.Nmul_A1989	7.249e-26	119.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,373HP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0250 family	ybeD	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
PYH1_k127_7261664_3	62928.azo0181	4.853e-110	365.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,2KVN6@206389|Rhodocyclales	206389|Rhodocyclales	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
PYH1_k127_7261664_2	1121035.AUCH01000025_gene3306	1.259e-147	492.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,2KVFQ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PYH1_k127_7261664_4	62928.azo0179	1.923e-91	310.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,2KUPW@206389|Rhodocyclales	206389|Rhodocyclales	DM	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
PYH1_k127_7261664_0	1235457.C404_22275	7.701e-164	541.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,1K38Y@119060|Burkholderiaceae	28216|Betaproteobacteria	F	dihydroorotase multifunctional complex type	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
PYH1_k127_7261664_1	1223521.BBJX01000016_gene721	8.938e-162	514.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,4ABIN@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
PYH1_k127_7261664_6	1000565.METUNv1_03050	2.764e-55	200.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,2KWGS@206389|Rhodocyclales	206389|Rhodocyclales	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
PYH1_k127_7261664_8	279714.FuraDRAFT_3592	6.212e-28	120.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,2KR8J@206351|Neisseriales	206351|Neisseriales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
PYH1_k127_7261664_5	85643.Tmz1t_3695	9.677e-80	274.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,2KVN5@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
PYH1_k127_7261664_10	582744.Msip34_2176	4.275e-25	108.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,2KKBP@206350|Nitrosomonadales	206350|Nitrosomonadales	L	PFAM DNA photolyase FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
PYH1_k127_7267196_6	69395.JQLZ01000007_gene1691	6.692e-94	316.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	MA20_32360	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH1_k127_7267196_3	1532557.JL37_20350	1.603e-168	542.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2VNJ6@28216|Betaproteobacteria,3T650@506|Alcaligenaceae	28216|Betaproteobacteria	E	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
PYH1_k127_7267196_1	1100720.ALKN01000037_gene1895	6.395e-186	595.0	COG0747@1|root,COG0747@2|Bacteria,1MWBH@1224|Proteobacteria,2VHY1@28216|Betaproteobacteria,4ABWB@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH1_k127_7267196_5	1382356.JQMP01000004_gene319	5.665e-104	360.0	COG3653@1|root,COG3653@2|Bacteria,2G86A@200795|Chloroflexi,27ZD5@189775|Thermomicrobia	189775|Thermomicrobia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
PYH1_k127_7267196_2	1100720.ALKN01000037_gene1895	1.735e-176	572.0	COG0747@1|root,COG0747@2|Bacteria,1MWBH@1224|Proteobacteria,2VHY1@28216|Betaproteobacteria,4ABWB@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH1_k127_7267196_4	1231391.AMZF01000009_gene1749	1.726e-133	432.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VJJU@28216|Betaproteobacteria,3T8WN@506|Alcaligenaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH1_k127_7267196_7	316058.RPB_1497	1.661e-84	304.0	COG1173@1|root,COG1173@2|Bacteria,1MVER@1224|Proteobacteria,2TRB3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PYH1_k127_7267196_0	1205680.CAKO01000040_gene991	1.794e-224	723.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2JPA1@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_7285759_8	1265502.KB905931_gene1710	2.626e-58	206.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,4AEJE@80864|Comamonadaceae	28216|Betaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
PYH1_k127_7285759_7	1323663.AROI01000006_gene2908	1.827e-112	376.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
PYH1_k127_7285759_0	640081.Dsui_2434	0.0	1067.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,2KVUA@206389|Rhodocyclales	206389|Rhodocyclales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
PYH1_k127_7285759_3	497321.C664_07058	3.944e-165	527.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2VHNH@28216|Betaproteobacteria,2KUZF@206389|Rhodocyclales	206389|Rhodocyclales	E	Aminotransferase	tyrB	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH1_k127_7285759_10	1320556.AVBP01000015_gene913	2.762e-26	114.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2UCYK@28211|Alphaproteobacteria,43KDC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH1_k127_7285759_9	323848.Nmul_A1168	1.213e-50	184.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,37347@32003|Nitrosomonadales	28216|Betaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7285759_2	1380355.JNIJ01000023_gene2439	1.128e-168	537.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,2TVAP@28211|Alphaproteobacteria,3JRAG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
PYH1_k127_7285759_5	864051.BurJ1DRAFT_3878	3.747e-138	447.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria	1224|Proteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
PYH1_k127_7285759_4	595537.Varpa_2326	6.308e-159	511.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2VJ5B@28216|Betaproteobacteria,4AC0Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
PYH1_k127_7285759_11	56780.SYN_01247	1.893e-05	50.0	2DCXT@1|root,2ZFR8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7285759_6	671143.DAMO_2284	1.506e-123	405.0	COG2116@1|root,COG2116@2|Bacteria,2NPFS@2323|unclassified Bacteria	2|Bacteria	P	Formate/nitrite transporter	focA	-	-	ko:K06212,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2	-	-	Form_Nir_trans
PYH1_k127_7285759_1	1458357.BG58_03115	1.322e-175	587.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VSSJ@28216|Betaproteobacteria,1K5FA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,SAM_1,TPR_12,Trans_reg_C
PYH1_k127_7291177_5	266264.Rmet_2492	1.253e-134	442.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1K16W@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
PYH1_k127_7291177_10	1158756.AQXQ01000012_gene1861	1.55e-28	129.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,1S2A7@1236|Gammaproteobacteria,1WXYQ@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
PYH1_k127_7291177_1	1532557.JL37_06940	1.891e-253	787.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria,3T3BF@506|Alcaligenaceae	28216|Betaproteobacteria	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
PYH1_k127_7291177_13	1000565.METUNv1_01928	4.461e-06	59.0	2EPEP@1|root,33H1B@2|Bacteria,1NHDJ@1224|Proteobacteria,2VXNY@28216|Betaproteobacteria,2KZUH@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3460
PYH1_k127_7291177_3	977880.RALTA_A1600	4.201e-199	640.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VHJZ@28216|Betaproteobacteria,1K1TX@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the citrate synthase family	prpC	-	2.3.3.5	ko:K01659	ko00640,map00640	-	R00931	RC00004,RC00406,RC02827	ko00000,ko00001,ko01000	-	-	-	Citrate_synt
PYH1_k127_7291177_6	1502852.FG94_04518	2.905e-130	435.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria,47299@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30,5.4.2.9	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	-	R00409,R00661	RC00286,RC00287,RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
PYH1_k127_7291177_4	1120999.JONM01000008_gene2046	1.327e-150	482.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,2KPYA@206351|Neisseriales	206351|Neisseriales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
PYH1_k127_7291177_8	305700.B447_15351	3.217e-38	147.0	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,2KWKD@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
PYH1_k127_7291177_9	395495.Lcho_2705	5.379e-37	148.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,1KKWA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Succinate dehydrogenase hydrophobic membrane anchor protein	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
PYH1_k127_7291177_0	243365.CV_1067	9.698e-257	811.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,2KPUX@206351|Neisseriales	206351|Neisseriales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PYH1_k127_7291177_7	1288494.EBAPG3_15710	6.039e-126	426.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,372KC@32003|Nitrosomonadales	28216|Betaproteobacteria	C	succinate dehydrogenase fumarate reductase	sdhB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
PYH1_k127_7291177_12	153948.NAL212_1784	8.603e-08	61.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,2VY7W@28216|Betaproteobacteria,373KF@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
PYH1_k127_7291177_2	1458357.BG58_39720	1.072e-226	708.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,1K1DC@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PYH1_k127_7291177_11	420662.Mpe_A2013	1.007e-22	113.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,1KJXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
PYH1_k127_7318071_4	323848.Nmul_A0189	1.679e-39	154.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,372Z1@32003|Nitrosomonadales	28216|Betaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
PYH1_k127_7318071_3	1000565.METUNv1_02095	2.286e-48	179.0	COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria,2KWU1@206389|Rhodocyclales	206389|Rhodocyclales	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7318071_0	1000565.METUNv1_02097	2.748e-124	404.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,2KVHR@206389|Rhodocyclales	206389|Rhodocyclales	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
PYH1_k127_7318071_2	1175306.GWL_35690	2.926e-67	236.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,473BA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Involved in biogenesis of respiratory and photosynthetic systems	senC	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
PYH1_k127_7318071_1	522306.CAP2UW1_4157	6.372e-108	357.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,1KPNV@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
PYH1_k127_7318071_5	1485544.JQKP01000001_gene1195	1.438e-36	141.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,44VHS@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
PYH1_k127_7351071_0	1266925.JHVX01000004_gene1140	9.256e-241	748.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,372U6@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Orn/Lys/Arg decarboxylase, C-terminal domain	-	-	4.1.1.19	ko:K01583	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
PYH1_k127_7351071_4	1335757.SPICUR_07525	1.018e-13	74.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
PYH1_k127_7351071_1	292415.Tbd_1855	1.221e-214	677.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,1KS1V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
PYH1_k127_7351071_2	266264.Rmet_2906	3.608e-62	241.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,2VMIR@28216|Betaproteobacteria,1K17Z@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
PYH1_k127_7351071_3	62928.azo1206	4.747e-54	195.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,2KVAZ@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
PYH1_k127_7351764_1	614083.AWQR01000002_gene2993	1.403e-152	491.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VJ7X@28216|Betaproteobacteria,4AD6C@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
PYH1_k127_7351764_0	1454004.AW11_04073	2.856e-162	537.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VHZA@28216|Betaproteobacteria,1KQFE@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Branched-chain amino acid transport system / permease component	urtC	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
PYH1_k127_7351764_2	1120999.JONM01000010_gene4166	4.752e-120	408.0	COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,2VIX4@28216|Betaproteobacteria,2KPGQ@206351|Neisseriales	206351|Neisseriales	S	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_7351764_3	85643.Tmz1t_3935	2.269e-116	377.0	COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,2VJUP@28216|Betaproteobacteria,2KV7I@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC transporter, ATP-binding protein	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
PYH1_k127_7351764_4	626418.bglu_1g07580	2.008e-22	99.0	COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2VHXH@28216|Betaproteobacteria,1K00J@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
PYH1_k127_7352192_14	641149.HMPREF9016_00583	1.501e-88	295.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,2KPUV@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
PYH1_k127_7352192_23	279714.FuraDRAFT_1513	4.741e-51	192.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VSIN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Molybdopterin-guanine dinucleotide biosynthesis protein MobA	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
PYH1_k127_7352192_8	1038869.AXAN01000006_gene856	3.855e-130	423.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,1K1XI@119060|Burkholderiaceae	28216|Betaproteobacteria	O	XdhC and CoxI family	coxI	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
PYH1_k127_7352192_10	1163617.SCD_n02307	1.711e-109	382.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2WGRW@28216|Betaproteobacteria	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
PYH1_k127_7352192_16	1163617.SCD_n02306	2.492e-75	265.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VQRM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH1_k127_7352192_21	864051.BurJ1DRAFT_4592	2.762e-60	236.0	COG0745@1|root,COG0745@2|Bacteria,1R8UQ@1224|Proteobacteria,2VQE1@28216|Betaproteobacteria,1KMZZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH1_k127_7352192_0	1304883.KI912532_gene2426	0.0	1274.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VKKR@28216|Betaproteobacteria,2KVH6@206389|Rhodocyclales	206389|Rhodocyclales	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
PYH1_k127_7352192_12	266264.Rmet_3837	1.439e-92	321.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,1K31F@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	CusF_Ec,HlyD_D23
PYH1_k127_7352192_13	582744.Msip34_1186	2.121e-91	317.0	COG1538@1|root,COG1538@2|Bacteria,1R744@1224|Proteobacteria,2VJW4@28216|Betaproteobacteria,2KKZE@206350|Nitrosomonadales	206350|Nitrosomonadales	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
PYH1_k127_7352192_19	1121033.AUCF01000029_gene326	1.596e-67	237.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,2JS2Q@204441|Rhodospirillales	204441|Rhodospirillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PYH1_k127_7352192_2	1095769.CAHF01000021_gene882	0.0	1207.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,4747B@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	coxL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH1_k127_7352192_11	365046.Rta_13390	2.488e-94	317.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VHV8@28216|Betaproteobacteria,4AAEZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	coxM	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
PYH1_k127_7352192_28	648885.KB316283_gene3030	2.654e-14	79.0	2DMF8@1|root,32R47@2|Bacteria,1RJ0J@1224|Proteobacteria,2UFI8@28211|Alphaproteobacteria,1JUPT@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
PYH1_k127_7352192_5	1207063.P24_09931	3.883e-138	445.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria,2JQDG@204441|Rhodospirillales	204441|Rhodospirillales	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
PYH1_k127_7352192_9	1121937.AUHJ01000003_gene3210	6.029e-130	428.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,1RY6X@1236|Gammaproteobacteria,469JX@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Malonyl-CoA decarboxylase N-terminal domain	-	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
PYH1_k127_7352192_6	402881.Plav_2958	3.307e-136	445.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,1MUHH@1224|Proteobacteria,2TSXR@28211|Alphaproteobacteria,1JNG5@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	VWA domain containing CoxE-like protein	MA20_09405	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
PYH1_k127_7352192_25	1218075.BAYA01000004_gene1338	1.511e-42	177.0	COG3427@1|root,COG3427@2|Bacteria,1RFSQ@1224|Proteobacteria,2VSTM@28216|Betaproteobacteria,1K1PS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	carbon monoxide dehydrogenase	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
PYH1_k127_7352192_30	1500306.JQLA01000012_gene2679	1.109e-08	67.0	COG2114@1|root,COG2114@2|Bacteria,1MWHK@1224|Proteobacteria,2TR2J@28211|Alphaproteobacteria,4BBYI@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
PYH1_k127_7352192_22	1123508.JH636440_gene2775	4.071e-54	199.0	COG2761@1|root,COG2761@2|Bacteria,2IYZM@203682|Planctomycetes	203682|Planctomycetes	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
PYH1_k127_7352192_20	1173021.ALWA01000037_gene3499	6.643e-65	226.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
PYH1_k127_7352192_3	1163617.SCD_n00836	7.849e-163	524.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	peptidase U62, modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
PYH1_k127_7352192_26	713587.THITH_13835	6.69e-42	161.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1WY21@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
PYH1_k127_7352192_24	760192.Halhy_0468	2.771e-47	175.0	2DMP1@1|root,32SS8@2|Bacteria,4NQY9@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0311 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
PYH1_k127_7352192_15	1163617.SCD_n00834	6.529e-79	274.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria	28216|Betaproteobacteria	H	molybdenum cofactor	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
PYH1_k127_7352192_1	1485544.JQKP01000003_gene117	0.0	1242.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,44W7T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
PYH1_k127_7352192_17	1366050.N234_07315	5.668e-73	260.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2VIS6@28216|Betaproteobacteria,1K1ID@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PYH1_k127_7352192_27	1415780.JPOG01000001_gene2342	6.968e-26	115.0	COG1309@1|root,COG1309@2|Bacteria,1N6FM@1224|Proteobacteria,1SZ1U@1236|Gammaproteobacteria,1XCWH@135614|Xanthomonadales	135614|Xanthomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PYH1_k127_7352192_18	1209072.ALBT01000032_gene2033	7.83e-68	247.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1FIIU@10|Cellvibrio	1236|Gammaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase,RyR,TPR_10,TPR_12
PYH1_k127_7352192_7	1000565.METUNv1_02959	3.109e-134	439.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,2KU8Q@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
PYH1_k127_7352192_4	292415.Tbd_2771	4.824e-162	531.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	yfhA	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
PYH1_k127_7352192_31	269799.Gmet_0104	1.733e-07	57.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,43TNF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
PYH1_k127_7358432_2	1095769.CAHF01000011_gene2197	1.29e-50	184.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,47391@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
PYH1_k127_7358432_1	1288826.MSNKSG1_02033	1.426e-61	224.0	COG0697@1|root,COG0697@2|Bacteria,1R6CU@1224|Proteobacteria,1SZQJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_7358432_0	247490.KSU1_C0714	2.659e-137	473.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
PYH1_k127_7358432_3	402777.KB235904_gene4520	3.639e-13	84.0	COG2931@1|root,COG3266@1|root,COG3391@1|root,COG4257@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG3391@2|Bacteria,COG4257@2|Bacteria,1GCE0@1117|Cyanobacteria,1HEJN@1150|Oscillatoriales	1117|Cyanobacteria	QV	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,DUF5122,HemolysinCabind
PYH1_k127_7362416_3	1380394.JADL01000003_gene5225	5.275e-08	54.0	COG2358@1|root,COG2358@2|Bacteria,1NRH6@1224|Proteobacteria,2TT34@28211|Alphaproteobacteria,2JQQ0@204441|Rhodospirillales	204441|Rhodospirillales	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
PYH1_k127_7362416_2	1123072.AUDH01000005_gene1662	4.855e-112	368.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,2TUR5@28211|Alphaproteobacteria,2JVHC@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_7362416_0	243365.CV_1113	8.351e-232	734.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,2KPMW@206351|Neisseriales	206351|Neisseriales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
PYH1_k127_7362416_1	305700.B447_18343	1.942e-231	738.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,2KUX1@206389|Rhodocyclales	206389|Rhodocyclales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
PYH1_k127_7451838_2	1217718.ALOU01000003_gene4630	8.985e-156	499.0	COG0436@1|root,COG0436@2|Bacteria,1MX6F@1224|Proteobacteria,2VJI9@28216|Betaproteobacteria,1K4H6@119060|Burkholderiaceae	28216|Betaproteobacteria	E	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
PYH1_k127_7451838_7	426117.M446_3050	5.799e-54	195.0	2BNSJ@1|root,32HG4@2|Bacteria,1MV5R@1224|Proteobacteria,2U1AN@28211|Alphaproteobacteria,1JU2R@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4337)	MA20_43880	-	-	-	-	-	-	-	-	-	-	-	DUF4337
PYH1_k127_7451838_3	1366050.N234_20010	2.208e-98	343.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VHMC@28216|Betaproteobacteria,1K2Q4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PYH1_k127_7451838_4	1123367.C666_16105	2.477e-94	323.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,2KUSD@206389|Rhodocyclales	206389|Rhodocyclales	KT	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
PYH1_k127_7451838_6	1121106.JQKB01000006_gene1309	1.184e-63	223.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria,2JWRR@204441|Rhodospirillales	204441|Rhodospirillales	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
PYH1_k127_7451838_8	1095769.CAHF01000011_gene2063	2.39e-32	126.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,474WK@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
PYH1_k127_7451838_1	522306.CAP2UW1_2584	7.007e-181	602.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
PYH1_k127_7451838_0	522306.CAP2UW1_2583	3.491e-316	983.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
PYH1_k127_7451838_5	522306.CAP2UW1_2582	5.752e-73	247.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	korC	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
PYH1_k127_7473796_0	1454004.AW11_01782	1.774e-266	835.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,1KPQQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
PYH1_k127_7473796_3	640081.Dsui_0892	1.975e-144	482.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,2KURV@206389|Rhodocyclales	206389|Rhodocyclales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
PYH1_k127_7473796_1	266264.Rmet_1385	3.108e-225	705.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,1K38Q@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
PYH1_k127_7473796_2	1500894.JQNN01000001_gene3519	7.45e-221	702.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,2VJMA@28216|Betaproteobacteria,4739B@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	-	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
PYH1_k127_7473796_4	395493.BegalDRAFT_1871	2.302e-29	127.0	2CCJR@1|root,2ZCU4@2|Bacteria,1RC7F@1224|Proteobacteria,1S3JC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7473796_5	1278073.MYSTI_03583	0.0001411	45.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria,2YW4H@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
PYH1_k127_7483522_0	864073.HFRIS_003498	1.008e-250	782.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,475WM@75682|Oxalobacteraceae	28216|Betaproteobacteria	EQ	Hydantoinase B/oxoprolinase	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
PYH1_k127_7494230_0	640081.Dsui_3403	8.601e-200	654.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,2KUGH@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971,DUF748
PYH1_k127_7494230_1	76114.ebA977	1.164e-123	407.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,2KVC4@206389|Rhodocyclales	206389|Rhodocyclales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
PYH1_k127_7515125_4	388051.AUFE01000002_gene461	4.321e-42	168.0	COG1028@1|root,COG1028@2|Bacteria,1MWGK@1224|Proteobacteria	1224|Proteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	MA20_16385	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
PYH1_k127_7515125_0	1441629.PCH70_39280	9.912e-132	432.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1Z6H0@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
PYH1_k127_7515125_1	1366050.N234_02495	2.889e-95	320.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,2VNEM@28216|Betaproteobacteria,1K5AJ@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH1_k127_7515125_5	1168059.KB899087_gene4093	1.69e-39	154.0	COG1853@1|root,COG1853@2|Bacteria,1MZKY@1224|Proteobacteria,2U22K@28211|Alphaproteobacteria,3EZZE@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PYH1_k127_7515125_7	438753.AZC_3032	1.933e-37	147.0	COG2059@1|root,COG2059@2|Bacteria,1RFMD@1224|Proteobacteria,2VG8D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	overlaps another CDS with the same product name	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
PYH1_k127_7515125_6	1125973.JNLC01000011_gene215	4.817e-39	164.0	COG2059@1|root,COG2059@2|Bacteria,1RAZW@1224|Proteobacteria,2U4CM@28211|Alphaproteobacteria,3JTFF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Chromate transporter	MA20_02260	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
PYH1_k127_7515125_2	404589.Anae109_2053	9.898e-83	280.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,42Q82@68525|delta/epsilon subdivisions,2WMBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
PYH1_k127_7515125_3	936455.KI421499_gene3674	5.844e-53	194.0	COG1853@1|root,COG1853@2|Bacteria,1MXPE@1224|Proteobacteria,2TS7H@28211|Alphaproteobacteria,3JSXQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PYH1_k127_7543614_1	1033802.SSPSH_002077	1.006e-105	354.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
PYH1_k127_7543614_3	977880.RALTA_B0540	5.608e-15	85.0	2E7PS@1|root,3325B@2|Bacteria,1PVAH@1224|Proteobacteria,2VVUK@28216|Betaproteobacteria,1KAP4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7543614_0	1121033.AUCF01000021_gene2889	4.387e-194	615.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria,2JQ2N@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
PYH1_k127_7543614_2	309801.trd_A0663	4.331e-58	224.0	COG0251@1|root,COG0251@2|Bacteria,2G7G4@200795|Chloroflexi,27Y7P@189775|Thermomicrobia	189775|Thermomicrobia	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
PYH1_k127_7543614_4	1218076.BAYB01000018_gene3413	0.0002885	53.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,2VRF3@28216|Betaproteobacteria,1K1BM@119060|Burkholderiaceae	28216|Betaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
PYH1_k127_7553280_4	398579.Spea_2700	3.433e-07	63.0	COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria,2QA00@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
PYH1_k127_7553280_2	748247.AZKH_4037	8.139e-74	262.0	COG3005@1|root,COG3005@2|Bacteria,1MV9J@1224|Proteobacteria,2WFG5@28216|Betaproteobacteria,2M048@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
PYH1_k127_7553280_3	637390.AFOH01000130_gene1979	7.32e-14	81.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria,2NCTJ@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH1_k127_7553280_0	1121035.AUCH01000001_gene1983	3.211e-113	370.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,2KU8F@206389|Rhodocyclales	206389|Rhodocyclales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
PYH1_k127_7553280_1	1454004.AW11_03935	1.712e-75	271.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,1KQQS@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
PYH1_k127_7553514_6	1208918.CDEE_0197	2.945e-12	68.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,1KQ1G@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
PYH1_k127_7553514_3	1123354.AUDR01000005_gene1592	9.104e-64	222.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2VQ7A@28216|Betaproteobacteria,1KRMM@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
PYH1_k127_7553514_0	580332.Slit_0757	9.688e-104	341.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2VHDK@28216|Betaproteobacteria,44VJR@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
PYH1_k127_7553514_2	312153.Pnuc_0042	1.924e-72	246.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2VPZW@28216|Betaproteobacteria,1K762@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
PYH1_k127_7553514_1	640081.Dsui_0371	5.365e-97	318.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2VKUA@28216|Betaproteobacteria,2KUIE@206389|Rhodocyclales	206389|Rhodocyclales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
PYH1_k127_7553514_4	76114.ebA3810	2.152e-43	160.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,2VUEX@28216|Betaproteobacteria,2KWR4@206389|Rhodocyclales	206389|Rhodocyclales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
PYH1_k127_7553514_5	1200567.JNKD01000071_gene1187	7.891e-17	79.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1Y3XP@135624|Aeromonadales	135624|Aeromonadales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
PYH1_k127_7571653_7	342113.DM82_251	1.047e-38	147.0	COG0350@1|root,COG0350@2|Bacteria,1RGB5@1224|Proteobacteria,2VRHP@28216|Betaproteobacteria,1KFU1@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Methylated-DNA- protein -cysteine S-methyltransferase	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
PYH1_k127_7571653_2	1163617.SCD_n02456	4.047e-110	369.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Tyrosine recombinase xerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PYH1_k127_7571653_4	62928.azo3220	1.893e-66	229.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,2VQAY@28216|Betaproteobacteria,2KW2N@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
PYH1_k127_7571653_8	395494.Galf_0204	5.073e-30	124.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,44VWI@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
PYH1_k127_7571653_5	859657.RPSI07_0920	1.178e-50	186.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,1K08V@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
PYH1_k127_7571653_3	1385517.N800_10165	4.88e-85	292.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1RR86@1236|Gammaproteobacteria,1XBY1@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
PYH1_k127_7571653_1	1163617.SCD_n02451	8.215e-136	440.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
PYH1_k127_7571653_9	522306.CAP2UW1_0459	6.415e-26	123.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,1KQ3W@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
PYH1_k127_7571653_6	1163617.SCD_n02449	1.154e-48	182.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria	28216|Betaproteobacteria	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
PYH1_k127_7571653_0	1163617.SCD_n02448	3.418e-178	576.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
PYH1_k127_7582376_1	522306.CAP2UW1_0506	1.371e-199	627.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,1KPS3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
PYH1_k127_7582376_9	1266925.JHVX01000009_gene92	2.658e-22	113.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,372YP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
PYH1_k127_7582376_6	1000565.METUNv1_02660	4.142e-85	312.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,2KUPN@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
PYH1_k127_7582376_5	1485544.JQKP01000001_gene885	6.618e-89	303.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,44V9I@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
PYH1_k127_7582376_4	640081.Dsui_3086	6.907e-141	472.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,2KVPI@206389|Rhodocyclales	206389|Rhodocyclales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
PYH1_k127_7582376_7	1266925.JHVX01000009_gene94	6.388e-74	253.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,3731S@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
PYH1_k127_7582376_8	1384054.N790_06400	3.862e-72	250.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1X5K2@135614|Xanthomonadales	135614|Xanthomonadales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
PYH1_k127_7582376_2	1187851.A33M_4207	6.994e-150	481.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	gltA	-	1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1,Pyr_redox_2
PYH1_k127_7582376_0	1187851.A33M_4208	1.443e-235	737.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3FCY5@34008|Rhodovulum	28211|Alphaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
PYH1_k127_7582376_3	1049564.TevJSym_bb00050	8.979e-142	467.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
PYH1_k127_759094_0	640081.Dsui_2797	1.168e-139	457.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,2KUQ6@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
PYH1_k127_759094_1	1163617.SCD_n01163	1.89e-117	384.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	dppF	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_7600144_11	1266925.JHVX01000007_gene2377	4.925e-34	135.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,373G3@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
PYH1_k127_7600144_0	323848.Nmul_A2553	0.0	1062.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,372MQ@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
PYH1_k127_7600144_8	1163617.SCD_n01709	5.462e-68	233.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VRPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
PYH1_k127_7600144_6	1126627.BAWE01000002_gene856	3.73e-118	389.0	COG2984@1|root,COG2984@2|Bacteria,1R7C2@1224|Proteobacteria,2TZKG@28211|Alphaproteobacteria,3JXR0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
PYH1_k127_7600144_10	1123392.AQWL01000011_gene2273	9.246e-48	173.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
PYH1_k127_7600144_7	323848.Nmul_A1854	4.756e-82	297.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,371MJ@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
PYH1_k127_7600144_1	1266925.JHVX01000009_gene60	2.834e-170	541.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,372MG@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
PYH1_k127_7600144_4	159087.Daro_1725	1.987e-142	462.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,2KVCM@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
PYH1_k127_7600144_5	626418.bglu_1g12600	1.304e-128	419.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,1K5F5@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
PYH1_k127_7600144_2	1000565.METUNv1_01316	5.227e-161	522.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,2KVDP@206389|Rhodocyclales	206389|Rhodocyclales	E	PFAM Aminotransferase class I and II	dapC	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH1_k127_7600144_9	1123368.AUIS01000004_gene237	1.508e-58	205.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,2NCX7@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
PYH1_k127_7600144_3	522306.CAP2UW1_3631	6.07e-149	487.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,1KQ8U@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
PYH1_k127_7613833_4	1349767.GJA_4028	1.798e-21	100.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,472H9@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
PYH1_k127_7613833_5	335283.Neut_2110	1.568e-18	98.0	COG1663@1|root,COG2835@1|root,COG1663@2|Bacteria,COG2835@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,372MY@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
PYH1_k127_7613833_1	1000565.METUNv1_01400	3.074e-96	334.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,2KU8U@206389|Rhodocyclales	206389|Rhodocyclales	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
PYH1_k127_7613833_3	323848.Nmul_A1028	1.753e-42	169.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,37383@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
PYH1_k127_7613833_2	640081.Dsui_3267	4.24e-83	284.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,2KV31@206389|Rhodocyclales	206389|Rhodocyclales	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
PYH1_k127_7613833_0	522306.CAP2UW1_0122	2.711e-105	348.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,1KQEI@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
PYH1_k127_7622075_0	522306.CAP2UW1_2887	0.0	1054.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,1KR7N@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
PYH1_k127_7622075_1	713586.KB900536_gene828	1.135e-57	212.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,1WZ7G@135613|Chromatiales	135613|Chromatiales	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
PYH1_k127_7629220_1	1304883.KI912532_gene1645	1.795e-09	67.0	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,2VQFW@28216|Betaproteobacteria,2KWI5@206389|Rhodocyclales	206389|Rhodocyclales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
PYH1_k127_7629220_0	1485544.JQKP01000001_gene1097	7.261e-103	344.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria,44V3S@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II and III secretion system protein	exeD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
PYH1_k127_7631543_3	338969.Rfer_2330	6.834e-99	327.0	COG2050@1|root,COG2050@2|Bacteria,1N57X@1224|Proteobacteria,2VTJB@28216|Betaproteobacteria,4AHYH@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
PYH1_k127_7631543_4	75379.Tint_0842	2.2e-84	284.0	COG0500@1|root,COG0500@2|Bacteria,1QVHC@1224|Proteobacteria,2VS83@28216|Betaproteobacteria,1KKW7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
PYH1_k127_7631543_10	69042.WH5701_05140	0.0001975	48.0	2B9PX@1|root,3232F@2|Bacteria,1GNN6@1117|Cyanobacteria,1H17E@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7631543_5	1123392.AQWL01000003_gene118	1.127e-71	263.0	COG2823@1|root,COG2823@2|Bacteria,1RFX5@1224|Proteobacteria,2VRR5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	BON domain	osmY	-	-	-	-	-	-	-	-	-	-	-	BON
PYH1_k127_7631543_2	640081.Dsui_1470	7.872e-104	345.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria,2KV4C@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
PYH1_k127_7631543_1	1411123.JQNH01000001_gene3657	7.674e-277	876.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	MA20_17495	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
PYH1_k127_7631543_6	1121106.JQKB01000015_gene5845	6.932e-64	222.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2JSBG@204441|Rhodospirillales	204441|Rhodospirillales	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
PYH1_k127_7631543_9	425104.Ssed_1240	2.883e-07	58.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,1SCRT@1236|Gammaproteobacteria,2QA0N@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
PYH1_k127_7631543_7	566466.NOR53_633	5.635e-42	163.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,1RRKY@1236|Gammaproteobacteria,1J6TT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
PYH1_k127_7631543_0	243365.CV_3661	4e-323	1009.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,2KPRZ@206351|Neisseriales	206351|Neisseriales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
PYH1_k127_7631543_8	1348657.M622_09175	1.052e-13	78.0	COG3218@1|root,COG3218@2|Bacteria,1N8NT@1224|Proteobacteria,2VSDM@28216|Betaproteobacteria,2KWR6@206389|Rhodocyclales	206389|Rhodocyclales	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
PYH1_k127_7632260_1	296591.Bpro_3022	1.376e-115	378.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VMVX@28216|Betaproteobacteria,4A9VB@80864|Comamonadaceae	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_7632260_2	1218075.BAYA01000004_gene1472	8.318e-69	259.0	COG0025@1|root,COG0025@2|Bacteria,1QTW8@1224|Proteobacteria,2WGFY@28216|Betaproteobacteria,1K2P3@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
PYH1_k127_7632260_0	93220.LV28_14375	2.413e-144	467.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2VK27@28216|Betaproteobacteria,1K3W2@119060|Burkholderiaceae	28216|Betaproteobacteria	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
PYH1_k127_7632260_3	365044.Pnap_3813	2.538e-35	136.0	COG3181@1|root,COG3181@2|Bacteria,1NSWQ@1224|Proteobacteria,2VHX6@28216|Betaproteobacteria,4AC2C@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_7641038_4	395495.Lcho_2910	0.0004021	47.0	2AXWX@1|root,31PY5@2|Bacteria,1QMKZ@1224|Proteobacteria,2W9V8@28216|Betaproteobacteria,1KNWK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7641038_1	1123392.AQWL01000001_gene1572	1.422e-144	467.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,1KRES@119069|Hydrogenophilales	119069|Hydrogenophilales	IM	LytB protein	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
PYH1_k127_7641038_2	93220.LV28_08900	6.996e-47	174.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,1K1IQ@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
PYH1_k127_7641038_0	1095769.CAHF01000011_gene2717	0.0	1291.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,473U5@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
PYH1_k127_7641038_3	323848.Nmul_A2653	1.099e-37	145.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,371XT@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
PYH1_k127_7676266_0	522306.CAP2UW1_3913	4.717e-242	759.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,1KQ6I@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
PYH1_k127_7676266_2	76114.ebA1246	6.572e-79	292.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,2KV2Q@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
PYH1_k127_7676266_1	573370.DMR_01270	1.42e-198	620.0	COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,42WCT@68525|delta/epsilon subdivisions,2WRX3@28221|Deltaproteobacteria,2MEBR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
PYH1_k127_7676266_3	573370.DMR_01260	8.835e-22	102.0	2D663@1|root,32TKM@2|Bacteria,1N455@1224|Proteobacteria,43DKS@68525|delta/epsilon subdivisions,2X8RY@28221|Deltaproteobacteria,2MFRP@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7676932_0	1071679.BG57_02305	1.226e-151	483.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,1K19M@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
PYH1_k127_7676932_1	713586.KB900536_gene901	2.242e-134	435.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1WW49@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
PYH1_k127_7676932_2	748247.AZKH_4228	3.065e-07	62.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,2KUTY@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rmlC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
PYH1_k127_7686707_2	522306.CAP2UW1_0623	8.425e-114	375.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VMD2@28216|Betaproteobacteria	28216|Betaproteobacteria	U	AAA domain	exeA1	-	-	-	-	-	-	-	-	-	-	-	AAA_22,SPOR
PYH1_k127_7686707_6	1485544.JQKP01000001_gene1098	1.123e-81	289.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2W994@28216|Betaproteobacteria,44WD7@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
PYH1_k127_7686707_8	1198452.Jab_2c02630	5.217e-76	264.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,477B7@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nosF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH1_k127_7686707_4	1121035.AUCH01000003_gene1189	3.398e-106	356.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,2KUXY@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
PYH1_k127_7686707_0	1123392.AQWL01000001_gene1546	5.733e-130	420.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,1KRYU@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
PYH1_k127_7686707_9	522306.CAP2UW1_0619	6.199e-60	223.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1KQR5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	Q	MlaD protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
PYH1_k127_7686707_7	640081.Dsui_1401	8.419e-78	274.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,2KW45@206389|Rhodocyclales	206389|Rhodocyclales	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
PYH1_k127_7686707_10	85643.Tmz1t_0892	2.74e-53	201.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,2KW7C@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
PYH1_k127_7686707_12	626418.bglu_1g03250	1.631e-14	77.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,2VXUB@28216|Betaproteobacteria,1K9F1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	STAS domain	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
PYH1_k127_7686707_1	640081.Dsui_1404	1.909e-122	404.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,2KVD2@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH1_k127_7686707_3	1286093.C266_22238	2.411e-113	377.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VH42@28216|Betaproteobacteria,1JZYY@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
PYH1_k127_7686707_11	1121004.ATVC01000003_gene482	4.84e-29	117.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
PYH1_k127_7686707_5	62928.azo0815	1.713e-101	335.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,2KUKJ@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
PYH1_k127_7690192_4	85643.Tmz1t_2957	1.018e-05	56.0	COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,2VT5X@28216|Betaproteobacteria,2KWJT@206389|Rhodocyclales	206389|Rhodocyclales	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PYH1_k127_7690192_0	946483.Cenrod_0414	2.808e-303	935.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,4AD4V@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
PYH1_k127_7690192_2	1123487.KB892840_gene74	6.1e-168	553.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria,2KVZU@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	padI	-	1.2.1.58	ko:K18356	ko00360,map00360	-	R02450	RC00004,RC02860	br01601,ko00000,ko00001,ko01000	-	-	-	Fer4_11,Fer4_6,TPP_enzyme_C
PYH1_k127_7690192_1	1123487.KB892840_gene75	2.124e-198	625.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria,2KVEF@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyruvate:ferredoxin oxidoreductase core domain II	padG	-	1.2.1.58	ko:K18355	ko00360,map00360	-	R02450	RC00004,RC02860	br01601,ko00000,ko00001,ko01000	-	-	-	PFOR_II,POR_N
PYH1_k127_7690192_3	1123487.KB892840_gene76	3.253e-82	278.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2VQ8C@28216|Betaproteobacteria,2KVM0@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	padE	-	1.2.1.58	ko:K18357	ko00360,map00360	-	R02450	RC00004,RC02860	br01601,ko00000,ko00001,ko01000	-	-	-	POR
PYH1_k127_7690192_5	631454.N177_2134	0.0002103	45.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,1JND8@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
PYH1_k127_7701833_0	640081.Dsui_0656	1.4e-219	695.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,2KUBP@206389|Rhodocyclales	206389|Rhodocyclales	KNT	COG0643 Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
PYH1_k127_7701833_1	85643.Tmz1t_3694	3.192e-93	310.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,2KUA4@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
PYH1_k127_7713666_1	316055.RPE_1781	2.753e-10	61.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2U149@28211|Alphaproteobacteria,3JTNK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	MA20_16350	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_7713666_0	443152.MDG893_18779	1.073e-134	447.0	COG0491@1|root,COG0494@1|root,COG0491@2|Bacteria,COG0494@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria,46AP6@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	blaB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,NUDIX
PYH1_k127_7723334_0	243160.BMA0622	8.239e-57	203.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,1K4HF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	2-Nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
PYH1_k127_7723334_2	1163617.SCD_n00378	1.05e-39	156.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	CRP FNR family	dnrD	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH1_k127_7723334_3	1121035.AUCH01000013_gene3085	5.898e-35	139.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,2KW8T@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH1_k127_7723334_4	1121035.AUCH01000013_gene3085	2.3e-34	139.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,2KW8T@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH1_k127_7723334_5	426114.THI_1182	1.167e-07	61.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,2VX02@28216|Betaproteobacteria,1KMH9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
PYH1_k127_7723334_1	395495.Lcho_1209	6.06e-41	160.0	COG3945@1|root,COG3945@2|Bacteria,1N12K@1224|Proteobacteria,2VUPY@28216|Betaproteobacteria,1KKSC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
PYH1_k127_7736429_7	1121035.AUCH01000005_gene104	4.899e-40	170.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUM4@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
PYH1_k127_7736429_3	640081.Dsui_0136	3.89e-117	398.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria,2WH69@28216|Betaproteobacteria	28216|Betaproteobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
PYH1_k127_7736429_15	1304883.KI912532_gene228	1.566e-10	66.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,2KXIN@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
PYH1_k127_7736429_10	1121939.L861_14390	2.367e-37	147.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1XRDR@135619|Oceanospirillales	135619|Oceanospirillales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
PYH1_k127_7736429_5	1255043.TVNIR_3060	4.334e-74	269.0	COG1352@1|root,COG1352@2|Bacteria,1RDBE@1224|Proteobacteria,1SJIV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
PYH1_k127_7736429_6	396588.Tgr7_2677	3.372e-67	234.0	COG1628@1|root,COG1628@2|Bacteria,1RCX1@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF99	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
PYH1_k127_7736429_13	1163617.SCD_n02299	2.582e-26	114.0	2E1FD@1|root,32WU2@2|Bacteria,1N5M2@1224|Proteobacteria,2VU9Q@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7736429_14	472759.Nhal_2247	1.149e-22	102.0	2E9MH@1|root,333U5@2|Bacteria,1NDRZ@1224|Proteobacteria,1STW7@1236|Gammaproteobacteria,1X1JP@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7736429_4	314278.NB231_06750	5.516e-95	323.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,1S0QR@1236|Gammaproteobacteria,1X00D@135613|Chromatiales	135613|Chromatiales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
PYH1_k127_7736429_9	292415.Tbd_1388	4.214e-38	149.0	COG0517@1|root,COG0517@2|Bacteria,1QTXQ@1224|Proteobacteria,2VWDB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
PYH1_k127_7736429_0	1411123.JQNH01000001_gene1616	1.101e-253	795.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PYH1_k127_7736429_1	671143.DAMO_1019	3.187e-158	533.0	COG1488@1|root,COG1488@2|Bacteria,2NNUE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
PYH1_k127_7736429_2	640081.Dsui_0162	1.151e-129	421.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,2KV65@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
PYH1_k127_7736429_8	159087.Daro_3470	1.368e-39	149.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria,2KWM1@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
PYH1_k127_7736429_11	1288494.EBAPG3_16190	3.394e-32	126.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,373IF@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
PYH1_k127_7736429_12	1203554.HMPREF1476_00090	3.787e-27	112.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,4PQPQ@995019|Sutterellaceae	28216|Betaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
PYH1_k127_7740567_1	640081.Dsui_0886	6.323e-33	130.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,2KUD1@206389|Rhodocyclales	206389|Rhodocyclales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH1_k127_7740567_2	640081.Dsui_0887	5.928e-24	105.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,2KWWQ@206389|Rhodocyclales	206389|Rhodocyclales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
PYH1_k127_7740567_0	640081.Dsui_0888	3.38e-201	630.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,2KUHG@206389|Rhodocyclales	206389|Rhodocyclales	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
PYH1_k127_7740567_3	1163617.SCD_n00098	3.501e-19	89.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
PYH1_k127_7742978_4	1288494.EBAPG3_1440	1.579e-292	901.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,371QW@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
PYH1_k127_7742978_41	349521.HCH_00659	2.476e-55	203.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S6JM@1236|Gammaproteobacteria,1XMHV@135619|Oceanospirillales	135619|Oceanospirillales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
PYH1_k127_7742978_27	580332.Slit_2416	4.866e-122	409.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
PYH1_k127_7742978_31	1304883.KI912532_gene1100	2.378e-105	348.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KV15@206389|Rhodocyclales	206389|Rhodocyclales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
PYH1_k127_7742978_42	580332.Slit_2921	2.048e-52	188.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,44VYE@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
PYH1_k127_7742978_7	1158292.JPOE01000002_gene2815	1.39e-244	761.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,1KJNG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
PYH1_k127_7742978_49	62928.azo0737	3.074e-21	100.0	2BWQ4@1|root,32QZV@2|Bacteria,1MZQ9@1224|Proteobacteria,2VSNR@28216|Betaproteobacteria,2KWKW@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
PYH1_k127_7742978_28	640081.Dsui_1050	2.176e-115	381.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KUZZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
PYH1_k127_7742978_11	1304883.KI912532_gene1214	3.774e-206	657.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KV3K@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
PYH1_k127_7742978_44	1332071.L581_4206	8.236e-45	177.0	COG1215@1|root,COG1215@2|Bacteria,1QVA7@1224|Proteobacteria,1T2F3@1236|Gammaproteobacteria,401HZ@613|Serratia	1236|Gammaproteobacteria	M	glycosyl transferase	-	-	-	ko:K12983,ko:K12988,ko:K19354	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
PYH1_k127_7742978_23	331869.BAL199_22262	5.849e-142	486.0	COG1893@1|root,COG1893@2|Bacteria,1QMH8@1224|Proteobacteria,2TSGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7742978_8	1038869.AXAN01000010_gene5129	5.891e-241	755.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2VJK0@28216|Betaproteobacteria,1K4T4@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
PYH1_k127_7742978_46	709797.CSIRO_4203	7.677e-38	160.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,3K2RR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N
PYH1_k127_7742978_29	1123393.KB891316_gene1774	2.936e-109	362.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,1KRN6@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
PYH1_k127_7742978_48	1121035.AUCH01000025_gene3321	1.946e-27	121.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria,2KWYJ@206389|Rhodocyclales	206389|Rhodocyclales	O	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
PYH1_k127_7742978_1	1163617.SCD_n00204	7.872e-305	947.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
PYH1_k127_7742978_30	397945.Aave_2459	7.1e-108	356.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,4AAPJ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
PYH1_k127_7742978_0	1095769.CAHF01000013_gene3197	0.0	1388.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,473JT@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
PYH1_k127_7742978_14	1095769.CAHF01000013_gene3196	1.998e-164	534.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,4733P@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	1.8.1.4,2.3.1.12	ko:K00382,ko:K00627	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R02569,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
PYH1_k127_7742978_6	1095769.CAHF01000013_gene3194	9.212e-258	827.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,473DP@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
PYH1_k127_7742978_36	1485544.JQKP01000001_gene932	6.606e-84	295.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria,44VEN@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A,Sugar-bind
PYH1_k127_7742978_43	397945.Aave_3047	2.607e-46	167.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,4AEC5@80864|Comamonadaceae	28216|Betaproteobacteria	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
PYH1_k127_7742978_19	1288494.EBAPG3_18220	1.038e-152	494.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria,372FT@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
PYH1_k127_7742978_39	1121035.AUCH01000003_gene1342	5.594e-64	227.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,2KW6H@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
PYH1_k127_7742978_34	76114.ebA1095	3.669e-90	299.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria,2KW4T@206389|Rhodocyclales	206389|Rhodocyclales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
PYH1_k127_7742978_47	1380394.JADL01000010_gene4101	4.042e-32	138.0	COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria,2UFSH@28211|Alphaproteobacteria,2JUW5@204441|Rhodospirillales	204441|Rhodospirillales	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH1_k127_7742978_9	1380394.JADL01000008_gene3518	1.218e-228	717.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,2JPTS@204441|Rhodospirillales	204441|Rhodospirillales	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
PYH1_k127_7742978_18	266264.Rmet_2590	1.347e-153	494.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJPJ@28216|Betaproteobacteria,1K05M@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the PdxA family	pdxA1	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1357_C,DUF1537,PdxA
PYH1_k127_7742978_13	365046.Rta_08990	3.5e-190	601.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,4AA1X@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_7742978_40	864051.BurJ1DRAFT_3903	1.074e-61	220.0	COG3090@1|root,COG3090@2|Bacteria,1R7TV@1224|Proteobacteria,2VPJP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_7742978_2	1211115.ALIQ01000206_gene4728	8.794e-305	943.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,3NC3N@45404|Beijerinckiaceae	28211|Alphaproteobacteria	EG	Dehydratase family	ilvD2	-	4.2.1.25	ko:K13875	ko00053,ko01100,map00053,map01100	-	R02522	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
PYH1_k127_7742978_32	224911.27352174	8.501e-98	324.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2TSDG@28211|Alphaproteobacteria,3JT3N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_27185	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
PYH1_k127_7742978_20	1095769.CAHF01000007_gene1659	2.058e-150	497.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2VNEK@28216|Betaproteobacteria,477GY@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PYH1_k127_7742978_16	864051.BurJ1DRAFT_0686	1.627e-163	518.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2VHA0@28216|Betaproteobacteria,1KKBG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
PYH1_k127_7742978_10	296591.Bpro_1258	5.248e-214	672.0	COG1653@1|root,COG1653@2|Bacteria,1MU64@1224|Proteobacteria,2VJYY@28216|Betaproteobacteria,4ACCN@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
PYH1_k127_7742978_22	1411123.JQNH01000001_gene143	5.472e-146	487.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	MA20_27205	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
PYH1_k127_7742978_33	331869.BAL199_19908	4.303e-93	334.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,2TQJ6@28211|Alphaproteobacteria,4BPVS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	MA20_27190	-	1.1.1.30	ko:K00019,ko:K18335	ko00051,ko00072,ko00650,ko01100,ko01120,map00051,map00072,map00650,map01100,map01120	M00088	R01361,R10690	RC00089,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
PYH1_k127_7742978_26	426117.M446_4912	2.866e-125	417.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria,1JT7P@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	ko:K18336	ko00051,ko01120,map00051,map01120	-	R10691	RC00326,RC03236	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
PYH1_k127_7742978_17	1157708.KB907453_gene4189	6.156e-159	525.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2VHQ8@28216|Betaproteobacteria,4AAK9@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM amidase, hydantoinase carbamoylase family	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
PYH1_k127_7742978_12	1297570.MESS4_710092	2.44e-198	631.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,43GQV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
PYH1_k127_7742978_50	2880.D8LTT1	2.201e-05	54.0	COG0666@1|root,KOG0504@2759|Eukaryota	2759|Eukaryota	I	protein ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4
PYH1_k127_7742978_24	76114.ebA2152	7.834e-133	436.0	COG0421@1|root,COG1586@1|root,COG0421@2|Bacteria,COG1586@2|Bacteria,1MVV5@1224|Proteobacteria,2WGFP@28216|Betaproteobacteria,2KUTH@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
PYH1_k127_7742978_35	748247.AZKH_2167	1.687e-89	305.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2VQIR@28216|Betaproteobacteria,2KW28@206389|Rhodocyclales	206389|Rhodocyclales	L	NADH pyrophosphatase-like rudimentary NUDIX domain	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
PYH1_k127_7742978_5	519989.ECTPHS_10154	1.814e-283	874.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1WXC1@135613|Chromatiales	135613|Chromatiales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
PYH1_k127_7742978_45	243233.MCA2744	5.412e-40	156.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S3XZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Ribulose bisphosphate carboxylase, small chain	-	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
PYH1_k127_7742978_37	420662.Mpe_A2785	1.034e-65	231.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,1KKV5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
PYH1_k127_7742978_25	1100721.ALKO01000017_gene1670	2.22e-132	432.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,4ACN6@80864|Comamonadaceae	28216|Betaproteobacteria	G	carbohydrate phosphatase activity	fbp1	-	3.1.3.11,3.1.3.37	ko:K01086	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase
PYH1_k127_7742978_21	1032480.MLP_19570	4.543e-146	484.0	COG3954@1|root,COG3954@2|Bacteria,2HHU6@201174|Actinobacteria,4DU1M@85009|Propionibacteriales	201174|Actinobacteria	C	Phosphoribulokinase / Uridine kinase family	prk	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
PYH1_k127_7742978_3	1123393.KB891331_gene2911	2.976e-300	932.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,1KRI8@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
PYH1_k127_7742978_15	395493.BegalDRAFT_1204	2.541e-164	538.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,4604G@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
PYH1_k127_7742978_38	1216976.AX27061_4922	4.124e-65	232.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,3T2U5@506|Alcaligenaceae	28216|Betaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
PYH1_k127_7743697_1	1255043.TVNIR_1860	4.194e-228	713.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WW29@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0027	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
PYH1_k127_7743697_0	1348657.M622_03350	2.932e-246	770.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,2KUH8@206389|Rhodocyclales	206389|Rhodocyclales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
PYH1_k127_7743697_3	1454004.AW11_02734	1.452e-160	516.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,1KQH6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	MoeA N-terminal region (domain I and II)	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
PYH1_k127_7743697_11	76114.ebA2945	2.033e-68	257.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,2KW8P@206389|Rhodocyclales	206389|Rhodocyclales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
PYH1_k127_7743697_8	1110502.TMO_1956	3.533e-107	360.0	COG2271@1|root,COG2271@2|Bacteria,1NJTU@1224|Proteobacteria,2TUBJ@28211|Alphaproteobacteria,2JPTM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_7743697_9	338969.Rfer_1001	6.249e-107	352.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VNH8@28216|Betaproteobacteria,4ADDR@80864|Comamonadaceae	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_7743697_10	1380394.JADL01000002_gene1160	1.97e-106	353.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2U1BU@28211|Alphaproteobacteria,2JW92@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PYH1_k127_7743697_6	1380394.JADL01000002_gene1159	9.614e-134	432.0	COG0559@1|root,COG0559@2|Bacteria,1MXGK@1224|Proteobacteria,2TVKT@28211|Alphaproteobacteria,2JVW1@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH1_k127_7743697_5	1380394.JADL01000002_gene1158	7.071e-142	471.0	COG4177@1|root,COG4177@2|Bacteria,1P0DF@1224|Proteobacteria,2TUBF@28211|Alphaproteobacteria,2JUXE@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH1_k127_7743697_2	1429916.X566_07215	2.058e-190	601.0	COG0683@1|root,COG0683@2|Bacteria,1MV1Z@1224|Proteobacteria,2TRTD@28211|Alphaproteobacteria,3JRR8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH1_k127_7743697_12	1144275.COCOR_05691	4.123e-64	241.0	COG1960@1|root,COG1960@2|Bacteria,1N2Q3@1224|Proteobacteria	1224|Proteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_M
PYH1_k127_7743697_7	85643.Tmz1t_3715	4.846e-117	385.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VK94@28216|Betaproteobacteria,2KV23@206389|Rhodocyclales	206389|Rhodocyclales	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
PYH1_k127_7743697_4	748247.AZKH_2874	1.324e-147	486.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
PYH1_k127_7743697_13	795666.MW7_2459	1.33e-35	146.0	2DBXD@1|root,2ZBP6@2|Bacteria,1RB44@1224|Proteobacteria,2VQT3@28216|Betaproteobacteria,1K3GG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3305
PYH1_k127_7743697_15	85643.Tmz1t_3713	2.721e-22	108.0	2DNW4@1|root,32ZGA@2|Bacteria,1N7ZK@1224|Proteobacteria,2VWJH@28216|Betaproteobacteria,2KXB6@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3306
PYH1_k127_7743697_14	232721.Ajs_3467	1.003e-32	134.0	COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2VMBE@28216|Betaproteobacteria,4ABEA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
PYH1_k127_7750704_0	1163617.SCD_n02025	3.016e-252	787.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	NADH Ubiquinone plastoquinone (Complex I)	hyfF	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
PYH1_k127_7750704_3	1163617.SCD_n02024	2.717e-89	299.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
PYH1_k127_7750704_2	1163617.SCD_n02023	1.43e-130	448.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2VKBD@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADH dehydrogenase	hyfD	-	-	-	-	-	-	-	-	-	-	-	NADHdh
PYH1_k127_7750704_1	76114.ebA4193	2.202e-227	722.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2VMAN@28216|Betaproteobacteria,2KVTE@206389|Rhodocyclales	206389|Rhodocyclales	CP	Proton-conducting membrane transporter	hyfB	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
PYH1_k127_7751591_0	1121127.JAFA01000002_gene1556	2.481e-144	467.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,1KCHF@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
PYH1_k127_7751591_4	85643.Tmz1t_2212	8.488e-27	123.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2VTZU@28216|Betaproteobacteria,2KWXS@206389|Rhodocyclales	206389|Rhodocyclales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
PYH1_k127_7751591_3	1122604.JONR01000014_gene215	1.439e-49	189.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,1S7MT@1236|Gammaproteobacteria,1X6HS@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
PYH1_k127_7751591_2	292415.Tbd_1004	7.255e-64	222.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,1KRPQ@119069|Hydrogenophilales	119069|Hydrogenophilales	I	YgbB family	-	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
PYH1_k127_7751591_1	748247.AZKH_2762	1.902e-70	245.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,2KVUZ@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
PYH1_k127_7754633_7	1121013.P873_04775	6.551e-16	82.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1RS3D@1236|Gammaproteobacteria,1XC2W@135614|Xanthomonadales	135614|Xanthomonadales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
PYH1_k127_7754633_0	1288494.EBAPG3_24790	4.012e-248	774.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2VKQG@28216|Betaproteobacteria,371QI@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the glutamate synthase family	glt	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
PYH1_k127_7754633_1	1366050.N234_25040	6.568e-206	675.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJ5E@28216|Betaproteobacteria,1K0Z0@119060|Burkholderiaceae	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_7754633_4	1304883.KI912532_gene2562	9.047e-138	452.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,2KU9G@206389|Rhodocyclales	206389|Rhodocyclales	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
PYH1_k127_7754633_2	864051.BurJ1DRAFT_4032	1.774e-183	584.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VJME@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_7754633_6	397945.Aave_3298	2.064e-55	199.0	COG3090@1|root,COG3090@2|Bacteria,1N01Z@1224|Proteobacteria	1224|Proteobacteria	G	transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_7754633_5	349521.HCH_06434	1.984e-100	337.0	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,1RQG9@1236|Gammaproteobacteria,1XHPC@135619|Oceanospirillales	135619|Oceanospirillales	G	TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_7754633_3	264198.Reut_A1259	5.14e-145	468.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2VIKG@28216|Betaproteobacteria,1K411@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Fad dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
PYH1_k127_7759365_18	864051.BurJ1DRAFT_2418	4.317e-09	61.0	COG0725@1|root,COG0725@2|Bacteria,1NY9R@1224|Proteobacteria,2VRYF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
PYH1_k127_7759365_5	296591.Bpro_0619	3.935e-133	432.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VPME@28216|Betaproteobacteria,4ADEN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_7759365_0	1381123.AYOD01000008_gene3276	1.2e-213	677.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2TRTQ@28211|Alphaproteobacteria,43IAZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the IlvD Edd family	MA20_38200	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PYH1_k127_7759365_12	1037409.BJ6T_61420	1.267e-48	198.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_7759365_2	1100721.ALKO01000021_gene587	1.713e-171	556.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,4ACB3@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_7759365_15	744980.TRICHSKD4_0437	1.606e-26	120.0	COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,2UFJP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_7759365_7	1100721.ALKO01000021_gene585	2.102e-88	302.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VP2F@28216|Betaproteobacteria,4AJA7@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_7759365_4	1205680.CAKO01000006_gene3262	1.43e-136	451.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JQI2@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_7759365_16	1123393.KB891332_gene2680	1.608e-21	96.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VVKE@28216|Betaproteobacteria,1KTBM@119069|Hydrogenophilales	119069|Hydrogenophilales	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
PYH1_k127_7759365_8	76114.ebA4672	8.698e-78	269.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2VKQH@28216|Betaproteobacteria,2KW5S@206389|Rhodocyclales	206389|Rhodocyclales	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
PYH1_k127_7759365_6	375286.mma_0185	2.725e-124	406.0	2C7F6@1|root,2Z8AK@2|Bacteria,1PEE5@1224|Proteobacteria,2VKQ6@28216|Betaproteobacteria,476M3@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7759365_9	1304883.KI912532_gene1759	2.237e-74	255.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2VHMQ@28216|Betaproteobacteria,2KX76@206389|Rhodocyclales	206389|Rhodocyclales	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
PYH1_k127_7759365_10	1177181.T9A_00330	5.253e-62	230.0	COG2199@1|root,COG3706@2|Bacteria,1RD8D@1224|Proteobacteria,1S78X@1236|Gammaproteobacteria,1XKSF@135619|Oceanospirillales	135619|Oceanospirillales	T	GGDEF domain	-	-	2.7.7.65	ko:K21019	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_4
PYH1_k127_7759365_13	234267.Acid_3392	3.111e-32	134.0	2E74W@1|root,331P9@2|Bacteria,3Y8XR@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
PYH1_k127_7759365_17	596154.Alide2_1176	1.01e-10	65.0	COG4118@1|root,COG4118@2|Bacteria,1QZE0@1224|Proteobacteria,2VYCX@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
PYH1_k127_7759365_14	936455.KI421499_gene4919	1.761e-31	132.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,2VGZ3@28211|Alphaproteobacteria,3JZA4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
PYH1_k127_7759365_1	316057.RPD_2526	4.125e-191	622.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,3JUS1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_2,TPR_8
PYH1_k127_7759365_3	62928.azo0915	5.815e-159	505.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria,2KUDJ@206389|Rhodocyclales	206389|Rhodocyclales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
PYH1_k127_7759365_11	395494.Galf_1400	6.494e-51	188.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,44UY8@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
PYH1_k127_7760522_2	396595.TK90_1074	4.531e-95	323.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1WWWM@135613|Chromatiales	135613|Chromatiales	O	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
PYH1_k127_7760522_4	96561.Dole_1528	9.914e-80	270.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42S15@68525|delta/epsilon subdivisions,2WNI1@28221|Deltaproteobacteria,2MNGZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
PYH1_k127_7760522_5	322710.Avin_49120	7.543e-76	265.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aldo keto	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,TAT_signal
PYH1_k127_7760522_0	1040989.AWZU01000011_gene4023	1.132e-144	469.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,2U1N0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
PYH1_k127_7760522_3	378806.STAUR_0942	5.868e-92	314.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,4383U@68525|delta/epsilon subdivisions,2X3DT@28221|Deltaproteobacteria,2YVM7@29|Myxococcales	28221|Deltaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PYH1_k127_7760522_1	1207063.P24_16075	2.168e-115	379.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2JVSZ@204441|Rhodospirillales	204441|Rhodospirillales	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
PYH1_k127_7770471_0	1316936.K678_00490	1.809e-200	634.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2U0QC@28211|Alphaproteobacteria,2JQ41@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase flavoprotein C-term	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
PYH1_k127_7770471_2	159087.Daro_3389	1.305e-151	497.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,2KVZN@206389|Rhodocyclales	206389|Rhodocyclales	G	C4-dicarboxylate transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_7770471_5	640081.Dsui_2533	1.003e-39	153.0	COG3090@1|root,COG3090@2|Bacteria,1RDY3@1224|Proteobacteria,2VRWQ@28216|Betaproteobacteria,2KX32@206389|Rhodocyclales	206389|Rhodocyclales	G	TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_7770471_1	977880.RALTA_A1249	7.145e-157	501.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VIJ6@28216|Betaproteobacteria,1KGPP@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_7770471_4	1123504.JQKD01000006_gene1433	1.683e-123	419.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,4ACTU@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Transketolase central region	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
PYH1_k127_7770471_3	1123504.JQKD01000006_gene1432	1.125e-132	430.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VIIQ@28216|Betaproteobacteria,4ADS6@80864|Comamonadaceae	28216|Betaproteobacteria	C	dehydrogenase, E1 component	pdhA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
PYH1_k127_7779601_1	1100721.ALKO01000016_gene1480	2.111e-15	85.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VJ7X@28216|Betaproteobacteria,4A9YV@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
PYH1_k127_7779601_0	1265502.KB905932_gene1805	1.539e-231	722.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2VI6J@28216|Betaproteobacteria,4A9XB@80864|Comamonadaceae	28216|Betaproteobacteria	E	amino acid	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
PYH1_k127_7780229_2	580340.Tlie_1327	1.311e-144	474.0	COG0018@1|root,COG0018@2|Bacteria,3TA5K@508458|Synergistetes	508458|Synergistetes	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
PYH1_k127_7780229_8	640081.Dsui_0674	5.606e-47	177.0	COG3087@1|root,COG3087@2|Bacteria,1RI6A@1224|Proteobacteria,2VR10@28216|Betaproteobacteria,2KWVJ@206389|Rhodocyclales	206389|Rhodocyclales	D	cell division protein	ftsN	-	-	-	-	-	-	-	-	-	-	-	SPOR
PYH1_k127_7780229_6	1265502.KB905937_gene2589	9.908e-56	201.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,4ADS0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin
PYH1_k127_7780229_11	314278.NB231_15023	4.42e-29	123.0	COG0607@1|root,COG0607@2|Bacteria,1N4H4@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
PYH1_k127_7780229_10	1000565.METUNv1_03311	1.079e-36	154.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,2KWSF@206389|Rhodocyclales	206389|Rhodocyclales	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA
PYH1_k127_7780229_5	522306.CAP2UW1_0984	2.67e-81	277.0	COG4221@1|root,COG4221@2|Bacteria,1QTVZ@1224|Proteobacteria,2WGPF@28216|Betaproteobacteria,1KQMP@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH1_k127_7780229_0	640081.Dsui_0971	1.001e-275	859.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KV59@206389|Rhodocyclales	206389|Rhodocyclales	I	poly(R)-hydroxyalkanoic acid synthase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
PYH1_k127_7780229_4	159087.Daro_0103	2.104e-108	361.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,2VKJX@28216|Betaproteobacteria,2KV95@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PYH1_k127_7780229_9	402626.Rpic_0130	2.372e-39	151.0	COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,2VSPA@28216|Betaproteobacteria,1K6Y3@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	zntR	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
PYH1_k127_7780229_1	1217720.ALOX01000032_gene194	2.104e-202	634.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,2JPCY@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_7780229_7	1298880.AUEV01000009_gene2956	4.334e-50	198.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	fcbC	-	-	ko:K07107,ko:K12500	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
PYH1_k127_7780229_3	93220.LV28_16380	1.336e-128	415.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1JZW5@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH1_k127_7786153_1	1163617.SCD_n02069	2.027e-79	270.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria	28216|Betaproteobacteria	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
PYH1_k127_7786153_0	887898.HMPREF0551_2342	3.099e-139	449.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VIHH@28216|Betaproteobacteria,1K1R3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cobalamin synthesis protein cobW C-terminal domain	yjiA_1	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
PYH1_k127_7786153_2	1163617.SCD_n00315	9.24e-05	48.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria	28216|Betaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_779050_1	1121035.AUCH01000013_gene3067	6.528e-227	709.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,2KUV2@206389|Rhodocyclales	206389|Rhodocyclales	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	-	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
PYH1_k127_779050_13	580332.Slit_2252	2.845e-48	181.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,44VVM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
PYH1_k127_779050_12	1454004.AW11_00663	2.325e-52	193.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,1KQ1B@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
PYH1_k127_779050_9	1392838.AWNM01000071_gene709	8.702e-71	241.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,3T3MV@506|Alcaligenaceae	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
PYH1_k127_779050_2	1434929.X946_3729	5.672e-208	662.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,1K14U@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
PYH1_k127_779050_10	1454004.AW11_00667	6.705e-66	228.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,1KQMC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Rrf2 family transcriptional regulator, iron-sulfur cluster assembly	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
PYH1_k127_779050_8	1223521.BBJX01000011_gene8	2.6e-91	306.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,4AAY0@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM Serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
PYH1_k127_779050_11	640081.Dsui_2367	2.366e-57	207.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,2KW30@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
PYH1_k127_779050_7	1163617.SCD_n01250	2.315e-101	342.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
PYH1_k127_779050_6	228410.NE2173	2.275e-112	372.0	COG1216@1|root,COG1216@2|Bacteria,1QVY8@1224|Proteobacteria,2VM73@28216|Betaproteobacteria,37322@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K13670	-	-	-	-	ko00000,ko01000	-	GT2	-	Glycos_transf_2
PYH1_k127_779050_16	1462526.BN990_01139	4.219e-27	115.0	COG2076@1|root,COG2076@2|Bacteria,1VF8J@1239|Firmicutes,4IRV7@91061|Bacilli	91061|Bacilli	P	Small Multidrug Resistance protein	arnF	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
PYH1_k127_779050_3	572477.Alvin_1795	3.328e-166	536.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RNEQ@1236|Gammaproteobacteria,1WXH9@135613|Chromatiales	135613|Chromatiales	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
PYH1_k127_779050_15	1266925.JHVX01000003_gene401	3.37e-30	129.0	COG0454@1|root,COG0456@2|Bacteria,1NDD2@1224|Proteobacteria,2WBWK@28216|Betaproteobacteria,373XJ@32003|Nitrosomonadales	28216|Betaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_779050_0	1205680.CAKO01000002_gene2647	3.715e-236	739.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TRRZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	MA20_06755	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
PYH1_k127_779050_18	1144275.COCOR_02117	2.632e-10	71.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,43ADI@68525|delta/epsilon subdivisions,2WPU6@28221|Deltaproteobacteria,2Z38F@29|Myxococcales	28221|Deltaproteobacteria	H	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
PYH1_k127_779050_14	266264.Rmet_5185	5.427e-47	172.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VR34@28216|Betaproteobacteria,1KFW6@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Reversible hydration of carbon dioxide	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
PYH1_k127_779050_17	313612.L8106_08756	4.328e-16	91.0	COG0385@1|root,COG0385@2|Bacteria,1G6ZW@1117|Cyanobacteria,1HFSU@1150|Oscillatoriales	1117|Cyanobacteria	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
PYH1_k127_779050_5	522306.CAP2UW1_2978	2.698e-128	417.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PYH1_k127_779050_19	748247.AZKH_3287	4.722e-10	64.0	2DMK8@1|root,32S5F@2|Bacteria,1NNIY@1224|Proteobacteria,2VUQF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
PYH1_k127_779050_4	1288494.EBAPG3_14160	1.694e-135	436.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VHVU@28216|Betaproteobacteria,371X3@32003|Nitrosomonadales	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
PYH1_k127_779880_2	305700.B447_10358	1.518e-57	204.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,2KW54@206389|Rhodocyclales	206389|Rhodocyclales	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
PYH1_k127_779880_3	1095769.CAHF01000010_gene1268	3.308e-35	144.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2VUBZ@28216|Betaproteobacteria,474N2@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
PYH1_k127_779880_0	323848.Nmul_A1541	0.0	1335.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,371VX@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
PYH1_k127_779880_4	1267535.KB906767_gene5521	1.891e-25	114.0	COG1678@1|root,COG1678@2|Bacteria,3Y8TX@57723|Acidobacteria	57723|Acidobacteria	K	Uncharacterized ACR, COG1678	-	-	-	-	-	-	-	-	-	-	-	-	DUF179
PYH1_k127_779880_6	330214.NIDE3217	1.363e-22	105.0	COG1678@1|root,COG1678@2|Bacteria	2|Bacteria	K	ribonucleoside-diphosphate reductase activity	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
PYH1_k127_779880_5	94624.Bpet2477	1.261e-22	102.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria,3T4MW@506|Alcaligenaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH1_k127_779880_7	1121405.dsmv_2550	7.623e-16	86.0	COG4770@1|root,COG4770@2|Bacteria,1NCKN@1224|Proteobacteria,42W8Y@68525|delta/epsilon subdivisions,2WRW7@28221|Deltaproteobacteria,2MM43@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
PYH1_k127_779880_1	1125863.JAFN01000001_gene3100	8.313e-173	550.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_7836442_4	1296990.H845_632	6.142e-05	47.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2TR3Q@28211|Alphaproteobacteria,2JR7F@204441|Rhodospirillales	204441|Rhodospirillales	F	CO dehydrogenase flavoprotein C-terminal domain	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
PYH1_k127_7836442_2	76114.ebA2063	6.702e-67	231.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ75@28216|Betaproteobacteria,2KW1Q@206389|Rhodocyclales	28216|Betaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3,1.3.7.9	ko:K03518,ko:K04107	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316,R11168	RC00490,RC02800	ko00000,ko00001,ko01000	-	-	-	Fer2,Fer2_2
PYH1_k127_7836442_0	76114.ebA2064	0.0	1245.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,2KYPD@206389|Rhodocyclales	206389|Rhodocyclales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH1_k127_7836442_1	76114.ebA2066	4.313e-162	549.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KXPJ@206389|Rhodocyclales	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH1_k127_7836442_3	76114.ebA2079	8.122e-17	94.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,2KU72@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in response to NO	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
PYH1_k127_7854299_15	765911.Thivi_0796	4.091e-62	220.0	COG4262@1|root,COG4262@2|Bacteria,1RFZS@1224|Proteobacteria,1S1NP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7854299_11	1123367.C666_02890	8.357e-97	329.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria,2KV5D@206389|Rhodocyclales	206389|Rhodocyclales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
PYH1_k127_7854299_12	305700.B447_01246	2.475e-92	327.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,2KVMZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
PYH1_k127_7854299_1	987059.RBXJA2T_03416	2.215e-241	752.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,1KIWD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
PYH1_k127_7854299_13	748247.AZKH_3115	1.855e-74	274.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,2KUET@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
PYH1_k127_7854299_5	265072.Mfla_1703	1.331e-153	493.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,2KMFH@206350|Nitrosomonadales	206350|Nitrosomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
PYH1_k127_7854299_4	748280.NH8B_1494	5.015e-168	552.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,2KPMB@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
PYH1_k127_7854299_6	640081.Dsui_3196	1.032e-142	483.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,2KUPN@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
PYH1_k127_7854299_10	1485544.JQKP01000003_gene249	6.423e-103	343.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,44V8K@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
PYH1_k127_7854299_14	76114.ebB163	8.457e-73	254.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,2KU7Q@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
PYH1_k127_7854299_2	748247.AZKH_3108	3.986e-227	709.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,2KUYW@206389|Rhodocyclales	206389|Rhodocyclales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH1_k127_7854299_9	85643.Tmz1t_3061	3.539e-110	365.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,2KV5S@206389|Rhodocyclales	206389|Rhodocyclales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
PYH1_k127_7854299_7	640081.Dsui_3190	1.998e-142	459.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,2KUCF@206389|Rhodocyclales	206389|Rhodocyclales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
PYH1_k127_7854299_8	1123487.KB892838_gene3864	1.708e-132	447.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,2KV9G@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
PYH1_k127_7854299_17	159087.Daro_0874	2.869e-26	115.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,2KWXH@206389|Rhodocyclales	206389|Rhodocyclales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
PYH1_k127_7854299_16	582744.Msip34_1541	7.792e-35	145.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,2KMQW@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
PYH1_k127_7854299_0	261292.Nit79A3_2464	2.003e-241	754.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,3723J@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
PYH1_k127_7854299_3	1266925.JHVX01000009_gene97	6.468e-172	548.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,371Y6@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
PYH1_k127_7854299_18	765910.MARPU_10735	3.748e-24	104.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1141@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1141@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1WX9H@135613|Chromatiales	135613|Chromatiales	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
PYH1_k127_786809_6	706587.Desti_1632	6.66e-19	102.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria,1MV1V@1224|Proteobacteria,42SUQ@68525|delta/epsilon subdivisions,2WPIY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
PYH1_k127_786809_1	887062.HGR_05459	3.694e-152	502.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,4AC6Q@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
PYH1_k127_786809_3	887062.HGR_05454	6.386e-105	347.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,4AARP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
PYH1_k127_786809_0	887062.HGR_05449	2.937e-201	648.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,4AAI7@80864|Comamonadaceae	28216|Betaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
PYH1_k127_786809_2	1458275.AZ34_07535	2.793e-129	429.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VMFC@28216|Betaproteobacteria,4AFKG@80864|Comamonadaceae	28216|Betaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
PYH1_k127_786809_4	887062.HGR_05439	4.214e-64	226.0	COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,2VTSY@28216|Betaproteobacteria,4AJFE@80864|Comamonadaceae	28216|Betaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
PYH1_k127_786809_5	768671.ThimaDRAFT_4664	4.395e-19	86.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria,1WXW3@135613|Chromatiales	135613|Chromatiales	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
PYH1_k127_7871694_6	335283.Neut_2372	2e-08	66.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,371PU@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
PYH1_k127_7871694_1	748247.AZKH_4447	2.431e-117	385.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,2KUA5@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
PYH1_k127_7871694_3	76114.c1A229	4.576e-75	262.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,2KUHY@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0631 Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
PYH1_k127_7871694_2	757424.Hsero_2133	1.917e-106	353.0	COG2123@1|root,COG2123@2|Bacteria,1R1R3@1224|Proteobacteria,2WI4G@28216|Betaproteobacteria,4793Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
PYH1_k127_7871694_4	265072.Mfla_0042	1.179e-71	258.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,2KKVM@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
PYH1_k127_7871694_0	883126.HMPREF9710_01948	3.747e-143	467.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,47263@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
PYH1_k127_7871694_5	113395.AXAI01000029_gene2756	1.538e-19	89.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,SAM_1
PYH1_k127_7896372_9	93220.LV28_16380	1.069e-161	513.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1JZW5@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH1_k127_7896372_26	395493.BegalDRAFT_1907	1.769e-28	130.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	MA20_08885	-	-	ko:K17362	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT
PYH1_k127_7896372_7	76114.ebA3640	3.156e-166	531.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,2KVJQ@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_7896372_3	640081.Dsui_0980	5.28e-262	834.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,2KVX8@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
PYH1_k127_7896372_21	1031711.RSPO_c03139	1.889e-82	296.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,1K3TY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
PYH1_k127_7896372_4	1123367.C666_09185	2.168e-237	752.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,2KV56@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
PYH1_k127_7896372_12	640081.Dsui_0984	3.447e-138	450.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VIUW@28216|Betaproteobacteria,2KUNG@206389|Rhodocyclales	206389|Rhodocyclales	E	HMGL-like	hmgL	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
PYH1_k127_7896372_19	744980.TRICHSKD4_5207	2.429e-111	369.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,2U2R9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH1_k127_7896372_18	1048339.KB913029_gene1970	8.93e-118	384.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria,4EVPG@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA4	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH1_k127_7896372_23	1385517.N800_06100	2.995e-70	243.0	COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,1S4K8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	5.99.1.4	ko:K14584	ko00626,ko01100,ko01120,ko01220,map00626,map01100,map01120,map01220	M00534	R05137	RC03084	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DSBA
PYH1_k127_7896372_17	1095769.CAHF01000013_gene3185	4.986e-118	387.0	COG2220@1|root,COG2220@2|Bacteria,1PH47@1224|Proteobacteria,2WAZ6@28216|Betaproteobacteria,4786C@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_7896372_8	640081.Dsui_1114	1.917e-165	534.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VHRJ@28216|Betaproteobacteria,2KUZ8@206389|Rhodocyclales	206389|Rhodocyclales	H	Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
PYH1_k127_7896372_13	742159.HMPREF0004_0456	7.357e-133	428.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHET@28216|Betaproteobacteria,3T2XB@506|Alcaligenaceae	28216|Betaproteobacteria	E	branched-chain amino acid	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_7896372_6	640081.Dsui_1112	2.321e-209	659.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,2VI33@28216|Betaproteobacteria,2KVMF@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_7896372_10	1304883.KI912532_gene537	1.041e-152	505.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VHRM@28216|Betaproteobacteria,2KV48@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_7896372_11	640081.Dsui_1110	5.175e-145	465.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,2VIID@28216|Betaproteobacteria,2KVZ8@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_7896372_15	640081.Dsui_1109	1.327e-125	430.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJ0Q@28216|Betaproteobacteria,2KVIG@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_7896372_2	762376.AXYL_06189	3.564e-292	909.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,3T1XK@506|Alcaligenaceae	28216|Betaproteobacteria	I	Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
PYH1_k127_7896372_0	402626.Rpic_0089	0.0	1603.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,1K4Q5@119060|Burkholderiaceae	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
PYH1_k127_7896372_20	1089544.KB912942_gene2024	1.186e-84	302.0	COG0235@1|root,COG0235@2|Bacteria,2GJ8W@201174|Actinobacteria,4E37X@85010|Pseudonocardiales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
PYH1_k127_7896372_14	1380394.JADL01000003_gene4756	3.009e-127	414.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria,2JUHF@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
PYH1_k127_7896372_22	639283.Snov_0102	3.222e-80	280.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3EYRF@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_7896372_5	794903.OPIT5_28955	4.732e-219	688.0	COG1032@1|root,COG1032@2|Bacteria,46V7P@74201|Verrucomicrobia,3K74V@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
PYH1_k127_7896372_24	292415.Tbd_2162	1.242e-57	213.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
PYH1_k127_7896372_27	207559.Dde_0009	2.625e-26	117.0	COG0500@1|root,COG2226@2|Bacteria,1RASQ@1224|Proteobacteria,42QTY@68525|delta/epsilon subdivisions,2WMN2@28221|Deltaproteobacteria,2MBR7@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
PYH1_k127_7896372_1	296591.Bpro_3491	0.0	1545.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,4A9J4@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
PYH1_k127_7896372_16	1234595.C725_1251	1.745e-122	410.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2TZU7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
PYH1_k127_7896372_25	1122603.ATVI01000006_gene825	3.716e-46	180.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1X5GK@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
PYH1_k127_7908513_0	398767.Glov_1025	1.658e-200	634.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,43T9E@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
PYH1_k127_7908513_2	365044.Pnap_3341	1.188e-41	163.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PYH1_k127_7908513_1	399795.CtesDRAFT_PD4686	1.838e-53	190.0	COG0346@1|root,COG0346@2|Bacteria,1RABQ@1224|Proteobacteria,2VS4J@28216|Betaproteobacteria,4AHTQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase bleomycin resistance	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH1_k127_7908513_4	1121920.AUAU01000005_gene933	1.566e-36	145.0	2EKGK@1|root,33E6M@2|Bacteria	2|Bacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH1_k127_7908513_5	582744.Msip34_2322	2.571e-29	119.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,2VU3I@28216|Betaproteobacteria,2KN4F@206350|Nitrosomonadales	206350|Nitrosomonadales	J	PFAM ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
PYH1_k127_7908513_3	522306.CAP2UW1_3336	1.187e-36	145.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,1KQSN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
PYH1_k127_7910818_0	84531.JMTZ01000014_gene2653	4.026e-58	212.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,1S22Y@1236|Gammaproteobacteria,1X63N@135614|Xanthomonadales	1236|Gammaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PYH1_k127_7910818_1	1236976.JCM16418_3723	1.744e-05	56.0	COG0277@1|root,COG0277@2|Bacteria,1UIU4@1239|Firmicutes,4HBGZ@91061|Bacilli,26QXD@186822|Paenibacillaceae	91061|Bacilli	C	FAD binding domain	yitY	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
PYH1_k127_7916693_2	402626.Rpic_1210	3.286e-18	84.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,1K41J@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
PYH1_k127_7916693_0	262724.TT_P0211	1.372e-127	419.0	COG1373@1|root,COG1373@2|Bacteria,1WJIW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PYH1_k127_7916693_1	748247.AZKH_1836	4.884e-21	92.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,2KVIZ@206389|Rhodocyclales	206389|Rhodocyclales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
PYH1_k127_7946602_0	159087.Daro_3515	0.0	1405.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,2KUYS@206389|Rhodocyclales	206389|Rhodocyclales	C	nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
PYH1_k127_7946602_3	557598.LHK_02080	2.667e-15	82.0	COG3062@1|root,COG3062@2|Bacteria	2|Bacteria	P	negative regulation of establishment of protein localization	napD	-	-	ko:K02570	-	-	-	-	ko00000	-	-	-	NapD
PYH1_k127_7946602_4	1410619.SRDD_08080	1.449e-10	66.0	COG1145@1|root,COG1149@1|root,COG1145@2|Bacteria,COG1149@2|Bacteria,1N09Y@1224|Proteobacteria,1S4EB@1236|Gammaproteobacteria,402Y7@613|Serratia	1236|Gammaproteobacteria	C	4Fe-4S dicluster domain	napF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896	-	ko:K02572	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7,Fer4_9
PYH1_k127_7946602_1	323848.Nmul_A1874	8.658e-142	458.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,372E9@32003|Nitrosomonadales	28216|Betaproteobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
PYH1_k127_7946602_2	1485544.JQKP01000005_gene326	1.009e-105	349.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,44V38@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
PYH1_k127_7949860_0	1163617.SCD_n02560	7.169e-134	438.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
PYH1_k127_7949860_1	748280.NH8B_4014	7.249e-78	282.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,2KPK9@206351|Neisseriales	206351|Neisseriales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
PYH1_k127_7949860_2	76114.ebA1327	1.214e-20	92.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,2KVVS@206389|Rhodocyclales	206389|Rhodocyclales	I	Acyltransferase	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
PYH1_k127_7970034_0	1163617.SCD_n02537	7.667e-118	387.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
PYH1_k127_7970034_1	296591.Bpro_1124	9.496e-56	203.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,4AASK@80864|Comamonadaceae	28216|Betaproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
PYH1_k127_7970034_2	257310.BB4621	5.323e-16	79.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,3T230@506|Alcaligenaceae	28216|Betaproteobacteria	CH	Ubiquinone biosynthesis	ubiF	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,SE
PYH1_k127_7985773_23	977880.RALTA_B0384	2.615e-86	291.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2VH34@28216|Betaproteobacteria,1KFIP@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
PYH1_k127_7985773_13	1163617.SCD_n00016	1.416e-119	401.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
PYH1_k127_7985773_24	1163617.SCD_n00185	1.09e-73	259.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VQDP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	transmembrane transcriptional regulator (Anti-sigma factor)	prtR	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
PYH1_k127_7985773_30	1395571.TMS3_0109270	1.378e-51	188.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,1S3GT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PYH1_k127_7985773_27	522306.CAP2UW1_0303	8.102e-68	237.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,1KQQW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	cyc	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
PYH1_k127_7985773_31	583345.Mmol_0294	1.176e-46	175.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,2KKZ0@206350|Nitrosomonadales	206350|Nitrosomonadales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
PYH1_k127_7985773_9	365046.Rta_03150	3.16e-156	498.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,4AB2M@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
PYH1_k127_7985773_29	391735.Veis_0283	6.799e-58	212.0	COG0346@1|root,COG0346@2|Bacteria,1MZT5@1224|Proteobacteria	1224|Proteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
PYH1_k127_7985773_7	1207063.P24_11295	1.84e-173	551.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2JPY3@204441|Rhodospirillales	204441|Rhodospirillales	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH1_k127_7985773_4	640081.Dsui_0718	1.471e-187	604.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,2KV4F@206389|Rhodocyclales	206389|Rhodocyclales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
PYH1_k127_7985773_32	497321.C664_19111	2.244e-36	152.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,2KX0I@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in tolerance to divalent cations	cutA1	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
PYH1_k127_7985773_22	1288494.EBAPG3_8820	4.67e-91	306.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,372CI@32003|Nitrosomonadales	28216|Betaproteobacteria	GM	PFAM NAD-dependent epimerase dehydratase	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
PYH1_k127_7985773_10	292415.Tbd_2563	4.444e-150	483.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,1KRC9@119069|Hydrogenophilales	119069|Hydrogenophilales	CH	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
PYH1_k127_7985773_25	604331.AUHY01000113_gene2329	1.02e-70	248.0	COG0410@1|root,COG0410@2|Bacteria,1WM3P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_7985773_17	477184.KYC_26217	2.188e-108	374.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,3T22A@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_7985773_11	522306.CAP2UW1_3610	3.33e-147	491.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,1KQDQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_7985773_15	1454004.AW11_00402	1.705e-116	383.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,1KQHA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_7985773_12	522306.CAP2UW1_3612	5.83e-136	450.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,1KQBE@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_7985773_2	292415.Tbd_2727	6.286e-249	790.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
PYH1_k127_7985773_28	1229172.JQFA01000004_gene379	1.738e-61	218.0	COG3803@1|root,COG3803@2|Bacteria,1G55K@1117|Cyanobacteria,1HAXI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial protein of	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
PYH1_k127_7985773_3	1095769.CAHF01000018_gene846	4.086e-230	722.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VHEI@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_7985773_1	1415779.JOMH01000001_gene2583	8.887e-284	884.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1X4TP@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
PYH1_k127_7985773_16	511.JT27_19050	2.027e-112	368.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,3T2ID@506|Alcaligenaceae	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
PYH1_k127_7985773_0	1095769.CAHF01000007_gene1651	0.0	1242.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VHCG@28216|Betaproteobacteria,472I0@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
PYH1_k127_7985773_26	1207063.P24_03825	6.211e-68	238.0	COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2TRBH@28211|Alphaproteobacteria,2JSI6@204441|Rhodospirillales	204441|Rhodospirillales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH1_k127_7985773_5	1207063.P24_03835	9.803e-187	592.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,2JQ78@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
PYH1_k127_7985773_19	977880.RALTA_A1653	1.747e-101	340.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,1K3K2@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH1_k127_7985773_14	375286.mma_1709	1.226e-116	384.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4731A@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_7985773_6	1095769.CAHF01000013_gene3211	3.743e-185	590.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIJX@28216|Betaproteobacteria,475ME@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	matB	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH1_k127_7985773_33	760117.JN27_21775	1.539e-10	73.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2VUHT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
PYH1_k127_7985773_20	1163617.SCD_n02855	5.195e-94	317.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
PYH1_k127_7985773_21	1121406.JAEX01000002_gene769	1.176e-91	310.0	COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,42P98@68525|delta/epsilon subdivisions,2WJWW@28221|Deltaproteobacteria,2MA81@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PYH1_k127_7985773_8	1217720.ALOX01000001_gene3399	2.394e-168	550.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,2JQAF@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
PYH1_k127_7985773_18	395493.BegalDRAFT_0266	1.773e-107	364.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,4615E@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
PYH1_k127_8003381_4	640081.Dsui_1276	3.473e-35	138.0	COG3807@1|root,COG3807@2|Bacteria,1MZIA@1224|Proteobacteria,2VUTD@28216|Betaproteobacteria,2KWXG@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
PYH1_k127_8003381_1	159087.Daro_0613	1.441e-49	185.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,2KW5X@206389|Rhodocyclales	206389|Rhodocyclales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
PYH1_k127_8003381_5	62928.azo2811	6.571e-29	117.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,2KWWG@206389|Rhodocyclales	206389|Rhodocyclales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
PYH1_k127_8003381_2	1121035.AUCH01000005_gene166	1.976e-39	150.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,2KWVI@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
PYH1_k127_8003381_3	640081.Dsui_1272	2.212e-39	161.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,2KWQT@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
PYH1_k127_8003381_0	1268622.AVS7_03404	4.034e-107	380.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2VHEK@28216|Betaproteobacteria,4AAD1@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
PYH1_k127_8029515_7	94624.Bpet3605	1.375e-89	303.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2VICR@28216|Betaproteobacteria	28216|Betaproteobacteria	H	4-carboxy-4-hydroxy-2-oxoadipate aldolase oxaloacetate decarboxylase	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
PYH1_k127_8029515_11	331869.BAL199_18396	2.254e-66	237.0	COG2084@1|root,COG2084@2|Bacteria,1MX8V@1224|Proteobacteria,2TVBS@28211|Alphaproteobacteria,4BSDB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Domain of unknown function (DUF1932)	MA20_26655	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
PYH1_k127_8029515_8	1040989.AWZU01000007_gene699	4.19e-77	279.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,3JUQJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	MA20_26650	-	-	-	-	-	-	-	-	-	-	-	NMT1
PYH1_k127_8029515_1	398525.KB900701_gene7408	1.185e-161	527.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,2TVM0@28211|Alphaproteobacteria,3JW6H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	ligJ	-	4.1.1.45,4.2.1.83	ko:K03392,ko:K10220	ko00362,ko00380,ko01100,ko01120,map00362,map00380,map01100,map01120	M00038	R04323,R04478	RC00498,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
PYH1_k127_8029515_5	1479235.KK366039_gene2072	4.121e-98	331.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,1RQD6@1236|Gammaproteobacteria,1XNZ4@135619|Oceanospirillales	135619|Oceanospirillales	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH1_k127_8029515_2	1298867.AUES01000029_gene2372	4.565e-115	379.0	COG3181@1|root,COG3181@2|Bacteria,1R8HR@1224|Proteobacteria,2U51E@28211|Alphaproteobacteria,3JV9T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_8029515_3	883078.HMPREF9695_02650	1.532e-106	357.0	COG0179@1|root,COG0179@2|Bacteria,1PPYQ@1224|Proteobacteria,2U1Q3@28211|Alphaproteobacteria,3K385@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
PYH1_k127_8029515_9	397945.Aave_3937	3.594e-74	275.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_8029515_12	1120983.KB894578_gene3773	1.756e-60	232.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
PYH1_k127_8029515_14	338969.Rfer_2737	3.178e-44	167.0	COG2204@1|root,COG2204@2|Bacteria,1P58Q@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PYH1_k127_8029515_13	338969.Rfer_2738	3.461e-53	198.0	COG2204@1|root,COG2204@2|Bacteria,1QZ6X@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PYH1_k127_8029515_10	338969.Rfer_2739	1.652e-72	257.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
PYH1_k127_8029515_6	338969.Rfer_2740	5.203e-92	325.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2VP9C@28216|Betaproteobacteria	1224|Proteobacteria	C	cytochrome	cbcB	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
PYH1_k127_8029515_0	338969.Rfer_2741	2.511e-214	679.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
PYH1_k127_8029515_4	338969.Rfer_2742	1.566e-103	342.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,2VP9Y@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
PYH1_k127_8032557_4	323848.Nmul_A2123	4.202e-47	174.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,3732C@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
PYH1_k127_8032557_5	640081.Dsui_2404	2.137e-41	165.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,2KWTR@206389|Rhodocyclales	206389|Rhodocyclales	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
PYH1_k127_8032557_3	640510.BC1001_2190	1.603e-77	275.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,1K1QM@119060|Burkholderiaceae	28216|Betaproteobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
PYH1_k127_8032557_0	1000565.METUNv1_01184	9.67e-160	514.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,2KU64@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_8032557_1	1121035.AUCH01000001_gene1900	2.639e-129	419.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VIX7@28216|Betaproteobacteria,2KU9Y@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH1_k127_8032557_2	1163617.SCD_n01786	1.242e-128	421.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
PYH1_k127_8032557_6	1502770.JQMG01000001_gene1977	1.717e-10	63.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,2KKFH@206350|Nitrosomonadales	206350|Nitrosomonadales	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
PYH1_k127_8041407_3	1500894.JQNN01000001_gene1114	1.181e-94	325.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2VJSU@28216|Betaproteobacteria,472GB@75682|Oxalobacteraceae	1500894.JQNN01000001_gene1114|-	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8041407_12	1244869.H261_09352	1.093e-51	190.0	COG0810@1|root,COG0810@2|Bacteria,1RJI3@1224|Proteobacteria,2U8TV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
PYH1_k127_8041407_4	1005048.CFU_3174	2.927e-86	296.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2VJ4U@28216|Betaproteobacteria,472IN@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	MotA/TolQ/ExbB proton channel family	exbB1	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
PYH1_k127_8041407_11	864051.BurJ1DRAFT_1595	2.864e-53	194.0	COG0848@1|root,COG0848@2|Bacteria,1RH4U@1224|Proteobacteria,2VSF4@28216|Betaproteobacteria,1KM48@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
PYH1_k127_8041407_10	864051.BurJ1DRAFT_1594	4.796e-54	194.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2VT16@28216|Betaproteobacteria,1KM2K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
PYH1_k127_8041407_5	1005048.CFU_3171	1.383e-85	298.0	COG0457@1|root,COG0457@2|Bacteria,1Q7UR@1224|Proteobacteria,2VKBS@28216|Betaproteobacteria,4768W@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
PYH1_k127_8041407_0	987059.RBXJA2T_08078	5.8e-245	776.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2VN0X@28216|Betaproteobacteria,1KPBW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
PYH1_k127_8041407_14	290397.Adeh_3376	4.067e-32	134.0	COG5516@1|root,COG5516@2|Bacteria,1N7M4@1224|Proteobacteria	1224|Proteobacteria	S	Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
PYH1_k127_8041407_1	502025.Hoch_2126	1.005e-228	721.0	COG2866@1|root,COG2866@2|Bacteria,1R586@1224|Proteobacteria,433ZT@68525|delta/epsilon subdivisions,2X4AT@28221|Deltaproteobacteria,2YYMP@29|Myxococcales	28221|Deltaproteobacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
PYH1_k127_8041407_2	1205680.CAKO01000005_gene3512	1.666e-113	379.0	COG2905@1|root,COG2905@2|Bacteria,1QUQR@1224|Proteobacteria,2TWQS@28211|Alphaproteobacteria,2JZ5M@204441|Rhodospirillales	204441|Rhodospirillales	T	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans,cNMP_binding
PYH1_k127_8041407_13	515635.Dtur_0932	7.277e-43	173.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_8041407_9	1231190.NA8A_07544	4.738e-60	218.0	COG0559@1|root,COG0559@2|Bacteria,1R6AI@1224|Proteobacteria,2U1TM@28211|Alphaproteobacteria,43KZ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH1_k127_8041407_6	1047013.AQSP01000127_gene472	1.469e-74	263.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BPD_transp_2
PYH1_k127_8041407_7	1231190.NA8A_07539	4.9e-70	246.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria,43JUX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	MA20_18645	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH1_k127_8041407_8	196162.Noca_0215	1.022e-67	241.0	COG0410@1|root,COG0410@2|Bacteria,2I93D@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH1_k127_8041407_16	1445613.JALM01000003_gene4954	1.499e-19	96.0	COG0730@1|root,COG0730@2|Bacteria,2IIJK@201174|Actinobacteria	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH1_k127_8065615_3	1198449.ACAM_0842	6.599e-09	58.0	COG0146@1|root,arCOG01512@2157|Archaea,2XQ2S@28889|Crenarchaeota	28889|Crenarchaeota	E	PFAM Hydantoinase B oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
PYH1_k127_8065615_1	706587.Desti_1835	4.5e-215	679.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2MS4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
PYH1_k127_8065615_0	706587.Desti_1834	3.373e-284	889.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2MQZU@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
PYH1_k127_8065615_2	316055.RPE_3220	1.618e-27	115.0	COG1802@1|root,COG1802@2|Bacteria,1NDRT@1224|Proteobacteria,2TUKM@28211|Alphaproteobacteria,3JUR2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	GntR family	MA20_10290	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH1_k127_8093996_19	85643.Tmz1t_2951	2.097e-85	299.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
PYH1_k127_8093996_17	85643.Tmz1t_2952	7.924e-93	317.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,2VUI3@28216|Betaproteobacteria,2KWVM@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	dch	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH1_k127_8093996_7	648757.Rvan_0035	6.268e-183	577.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH1_k127_8093996_6	748247.AZKH_2909	2.497e-223	706.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria,2KY1I@206389|Rhodocyclales	206389|Rhodocyclales	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
PYH1_k127_8093996_15	85643.Tmz1t_2956	1.968e-128	439.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria,2KY5Y@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
PYH1_k127_8093996_27	1123355.JHYO01000018_gene1661	4.071e-29	133.0	COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,2U6JY@28211|Alphaproteobacteria,36Z1C@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PYH1_k127_8093996_25	1244869.H261_12176	6.967e-54	193.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria,2JSX2@204441|Rhodospirillales	204441|Rhodospirillales	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
PYH1_k127_8093996_18	314264.ROS217_00560	8.611e-91	305.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2TSDG@28211|Alphaproteobacteria,46RS3@74030|Roseovarius	28211|Alphaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH1_k127_8093996_30	1165096.ARWF01000001_gene194	9.59e-14	74.0	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,2VWE5@28216|Betaproteobacteria,2KN7Q@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8093996_3	1071679.BG57_25465	5.435e-287	894.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,1K30A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
PYH1_k127_8093996_8	522306.CAP2UW1_4176	4.259e-175	560.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,1KPU6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
PYH1_k127_8093996_13	395495.Lcho_0045	4.209e-133	439.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
PYH1_k127_8093996_28	395495.Lcho_0046	1.236e-28	123.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2VVWD@28216|Betaproteobacteria,1KPCJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
PYH1_k127_8093996_11	1037409.BJ6T_69060	5.828e-156	528.0	COG2203@1|root,COG4191@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3K6MV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,dCache_1
PYH1_k127_8093996_31	443598.AUFA01000004_gene5385	0.0001024	46.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_8093996_9	713586.KB900536_gene1287	6.85e-160	520.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8093996_21	472759.Nhal_3549	2.088e-65	229.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1WYN6@135613|Chromatiales	135613|Chromatiales	K	SMART cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH1_k127_8093996_5	1095769.CAHF01000003_gene1016	1.585e-239	747.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VIHR@28216|Betaproteobacteria,472CJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
PYH1_k127_8093996_0	1163408.UU9_14265	0.0	2353.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1X465@135614|Xanthomonadales	135614|Xanthomonadales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
PYH1_k127_8093996_14	85643.Tmz1t_0840	7.243e-132	433.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,2KURZ@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
PYH1_k127_8093996_23	381666.H16_A3435	1.662e-58	207.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,1K1DP@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
PYH1_k127_8093996_4	1000565.METUNv1_01943	9.287e-245	778.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KUHK@206389|Rhodocyclales	206389|Rhodocyclales	U	Type 4 fimbrial biogenesis protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
PYH1_k127_8093996_29	1033802.SSPSH_003542	2.662e-24	111.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	pilus assembly protein pilp	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
PYH1_k127_8093996_20	640081.Dsui_1189	9.175e-71	245.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,2KW2A@206389|Rhodocyclales	206389|Rhodocyclales	NU	Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
PYH1_k127_8093996_24	1304883.KI912532_gene578	4.603e-57	209.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,2VN9T@28216|Betaproteobacteria,2KWD2@206389|Rhodocyclales	206389|Rhodocyclales	NU	fimbrial biogenesis protein PilN	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
PYH1_k127_8093996_12	640081.Dsui_1187	2.254e-148	478.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria,2KV8N@206389|Rhodocyclales	206389|Rhodocyclales	NU	Pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
PYH1_k127_8093996_2	640081.Dsui_1186	5e-324	1007.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,2KU7U@206389|Rhodocyclales	206389|Rhodocyclales	M	penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
PYH1_k127_8093996_26	1454004.AW11_02621	5.26e-30	131.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,2VVS3@28216|Betaproteobacteria,1KQ5H@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Inorganic ion transport and metabolism	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
PYH1_k127_8093996_10	1000565.METUNv1_01934	1.545e-156	503.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,2KVC9@206389|Rhodocyclales	206389|Rhodocyclales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
PYH1_k127_8093996_16	335543.Sfum_0450	1.327e-97	331.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,2MR7H@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PYH1_k127_8093996_1	880072.Desac_1402	0.0	1287.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2MR8V@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
PYH1_k127_8093996_22	266264.Rmet_3896	3.63e-62	218.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2VH34@28216|Betaproteobacteria,1KFIP@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
PYH1_k127_8097282_6	1005999.GLGR_0439	1.331e-07	55.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
PYH1_k127_8097282_4	1379698.RBG1_1C00001G0889	1.848e-35	139.0	COG4747@1|root,COG4747@2|Bacteria,2NR4R@2323|unclassified Bacteria	2|Bacteria	S	ACT domain protein	hom	-	1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19	ko:K00003,ko:K00058,ko:K01754,ko:K04767	ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00017,M00018,M00020,M00570	R00220,R00996,R01513,R01773,R01775	RC00031,RC00087,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3
PYH1_k127_8097282_2	883126.HMPREF9710_03181	5.201e-71	245.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,47268@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Cobalamin adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
PYH1_k127_8097282_5	1341679.P253_00411	2.643e-30	130.0	COG3471@1|root,COG3471@2|Bacteria,1MZA2@1224|Proteobacteria,1S793@1236|Gammaproteobacteria,3NJEW@468|Moraxellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF541)	Z012_10940	-	-	-	-	-	-	-	-	-	-	-	SIMPL
PYH1_k127_8097282_1	1341646.CBMO010000015_gene6286	9.755e-88	295.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,2341D@1762|Mycobacteriaceae	201174|Actinobacteria	S	haloacid dehalogenase	dehII	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
PYH1_k127_8097282_3	1057002.KB905371_gene17	1.894e-46	178.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
PYH1_k127_8097282_0	795666.MW7_0585	3.2e-96	323.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_8106309_5	795666.MW7_1791	2.709e-62	222.0	COG3181@1|root,COG3181@2|Bacteria,1NTB7@1224|Proteobacteria,2W167@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_8106309_1	1121861.KB899916_gene1772	3.184e-154	496.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales	204441|Rhodospirillales	C	III protein, CoA-transferase family	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH1_k127_8106309_0	1110502.TMO_1175	5.656e-225	721.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JQ9H@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH1_k127_8106309_2	45351.EDO26359	4.202e-115	398.0	COG1012@1|root,KOG2451@2759|Eukaryota	2759|Eukaryota	C	succinate-semialdehyde dehydrogenase (NAD+) activity	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH1_k127_8106309_4	543728.Vapar_4930	2.757e-74	272.0	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2VQD1@28216|Betaproteobacteria,4ACGY@80864|Comamonadaceae	28216|Betaproteobacteria	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
PYH1_k127_8106309_3	713586.KB900536_gene702	1.143e-110	366.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,1RRSU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	comC	-	1.1.1.338,1.5.1.21	ko:K13609,ko:K16844	ko00270,ko00310,ko00960,ko01100,ko01120,map00270,map00310,map00960,map01100,map01120	-	R02203,R07137	RC00031,RC00135	ko00000,ko00001,ko01000	-	-	-	Ldh_2
PYH1_k127_8108681_3	1097668.BYI23_A015270	1.479e-05	50.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,1JZYN@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PYH1_k127_8108681_1	1454004.AW11_00552	2.54e-112	368.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KQ3X@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
PYH1_k127_8108681_2	1005048.CFU_3497	5.847e-108	358.0	COG0451@1|root,COG0451@2|Bacteria,1MU1A@1224|Proteobacteria,2VHGA@28216|Betaproteobacteria,472GQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Male sterility protein	-	-	1.1.1.410	ko:K22025	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
PYH1_k127_8108681_0	1266925.JHVX01000001_gene2591	3.062e-118	387.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,371US@32003|Nitrosomonadales	28216|Betaproteobacteria	L	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
PYH1_k127_8114233_1	1205680.CAKO01000002_gene3122	3.683e-49	181.0	COG0477@1|root,COG2814@2|Bacteria,1QV32@1224|Proteobacteria,2TW9N@28211|Alphaproteobacteria,2JZ40@204441|Rhodospirillales	204441|Rhodospirillales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_8114233_0	1095769.CAHF01000001_gene3532	8.523e-96	321.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VJ4C@28216|Betaproteobacteria,473B4@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Phosphatidylethanolamine-binding protein	bbsI	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
PYH1_k127_8114233_2	157783.LK03_10440	1.131e-10	66.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH1_k127_8131505_2	159087.Daro_1049	1.354e-35	141.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,2VINE@28216|Betaproteobacteria,2KW29@206389|Rhodocyclales	206389|Rhodocyclales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
PYH1_k127_8131505_0	62928.azo1352	6.272e-199	629.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,2KVK4@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
PYH1_k127_8131505_1	1038869.AXAN01000003_gene2814	3.5e-89	308.0	COG4585@1|root,COG4585@2|Bacteria,1R43J@1224|Proteobacteria,2VPEB@28216|Betaproteobacteria,1K250@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02486	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HATPase_c_2,HisKA_3,PAS,PAS_4,PAS_9
PYH1_k127_8141023_5	1007105.PT7_0669	3.561e-54	197.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2WGUW@28216|Betaproteobacteria,3T60B@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH1_k127_8141023_0	381666.H16_A2589	1.081e-183	581.0	COG1488@1|root,COG1488@2|Bacteria,1MV8U@1224|Proteobacteria,2VGZ5@28216|Betaproteobacteria,1K2JW@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
PYH1_k127_8141023_4	1123368.AUIS01000006_gene572	1.306e-63	224.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,2NCEE@225057|Acidithiobacillales	225057|Acidithiobacillales	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
PYH1_k127_8141023_1	1123392.AQWL01000003_gene278	2.754e-76	262.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VHTZ@28216|Betaproteobacteria,1KS7H@119069|Hydrogenophilales	119069|Hydrogenophilales	KT	LexA DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LexA_DNA_bind,Peptidase_S24
PYH1_k127_8141023_3	1158165.KB898872_gene1134	4.356e-72	268.0	COG0642@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1T44K@1236|Gammaproteobacteria,1WXW4@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
PYH1_k127_8141023_6	1244869.H261_16488	3.844e-32	129.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,2UBY6@28211|Alphaproteobacteria,2JT8D@204441|Rhodospirillales	204441|Rhodospirillales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PYH1_k127_8141023_2	105559.Nwat_2753	6.015e-74	263.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1WX4U@135613|Chromatiales	135613|Chromatiales	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
PYH1_k127_8157282_1	1163617.SCD_n02070	1.1e-71	250.0	COG0500@1|root,COG2226@2|Bacteria,1NRR4@1224|Proteobacteria,2W05F@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
PYH1_k127_8157282_4	1238182.C882_4201	7.359e-24	104.0	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2UI14@28211|Alphaproteobacteria,2JUB3@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase subunit D	-	-	-	-	-	-	-	-	-	-	-	-	Fumarate_red_D
PYH1_k127_8157282_3	1238182.C882_4200	1.526e-29	132.0	COG3029@1|root,COG3029@2|Bacteria,1RD34@1224|Proteobacteria,2UFZX@28211|Alphaproteobacteria,2JUG8@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase subunit C	-	-	-	-	-	-	-	-	-	-	-	-	Fumarate_red_C
PYH1_k127_8157282_0	1238182.C882_4199	1.485e-100	338.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2U3AH@28211|Alphaproteobacteria,2JRIM@204441|Rhodospirillales	204441|Rhodospirillales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_3,Fer4_8
PYH1_k127_8157282_2	1238182.C882_4198	2.961e-44	165.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2U0QC@28211|Alphaproteobacteria,2JQ41@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase flavoprotein C-term	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
PYH1_k127_8163762_6	1320556.AVBP01000016_gene2752	4.826e-09	59.0	COG1719@1|root,COG1719@2|Bacteria,1PZY6@1224|Proteobacteria,2UV2G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	V4R	-	-	-	-	-	-	-	-	-	-	-	-	V4R
PYH1_k127_8163762_0	1411123.JQNH01000001_gene3240	1.09e-87	301.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TTP8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	bcpA	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
PYH1_k127_8163762_3	388051.AUFE01000030_gene5114	6.653e-36	141.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,2VSZM@28216|Betaproteobacteria,1KB0B@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
PYH1_k127_8163762_4	1502851.FG93_03414	3.186e-25	111.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	bacB	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017000,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046872,GO:0046914,GO:0050897	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CDO_I,Cupin_2
PYH1_k127_8163762_5	1502852.FG94_04728	1.257e-16	88.0	COG3637@1|root,COG3637@2|Bacteria,1PWWU@1224|Proteobacteria,2WCF6@28216|Betaproteobacteria,477GQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl
PYH1_k127_8163762_1	381666.PHG400	5.739e-85	293.0	COG3181@1|root,COG3181@2|Bacteria,1R8DS@1224|Proteobacteria,2W1MT@28216|Betaproteobacteria,1K4EH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_8163762_2	1392838.AWNM01000027_gene4552	1.848e-56	199.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNG@28216|Betaproteobacteria,3T1SK@506|Alcaligenaceae	28216|Betaproteobacteria	E	branched-chain amino acid transport	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_8200878_3	85643.Tmz1t_2977	1.98e-22	100.0	COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,2VV8Y@28216|Betaproteobacteria,2KWY8@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
PYH1_k127_8200878_1	76114.ebA5362	1.338e-135	447.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VHPP@28216|Betaproteobacteria,2KVZ4@206389|Rhodocyclales	206389|Rhodocyclales	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_8200878_2	365046.Rta_24910	4.419e-33	141.0	COG3090@1|root,COG3090@2|Bacteria,1N9D4@1224|Proteobacteria,2VT71@28216|Betaproteobacteria,4AFK4@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_8200878_0	365046.Rta_24900	1.528e-168	543.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,4ACB3@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH1_k127_8200878_4	941449.dsx2_0621	1.723e-09	62.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria,2MAJ6@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	AMP-binding enzyme C-terminal domain	bamY	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2143	AMP-binding,AMP-binding_C
PYH1_k127_8205074_7	1205680.CAKO01000002_gene3005	6.179e-58	220.0	COG4177@1|root,COG4177@2|Bacteria,1NE3E@1224|Proteobacteria,2TTWY@28211|Alphaproteobacteria,2JT5A@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH1_k127_8205074_5	1187851.A33M_0278	9.152e-106	352.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2TSH5@28211|Alphaproteobacteria,3FEM5@34008|Rhodovulum	28211|Alphaproteobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_8205074_3	1121033.AUCF01000030_gene174	3.307e-129	424.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2U16N@28211|Alphaproteobacteria,2JVNK@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH1_k127_8205074_2	1121033.AUCF01000030_gene174	8.818e-143	464.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2U16N@28211|Alphaproteobacteria,2JVNK@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH1_k127_8205074_0	1231391.AMZF01000017_gene178	3.765e-208	664.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2VIB6@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fcs	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
PYH1_k127_8205074_4	1121033.AUCF01000016_gene5484	2.972e-118	415.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2TSQB@28211|Alphaproteobacteria,2JU12@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
PYH1_k127_8205074_10	953739.SVEN_4281	7.734e-35	149.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria	201174|Actinobacteria	Q	catechol 1,2-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
PYH1_k127_8205074_9	1380394.JADL01000003_gene5159	8.285e-56	196.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,2JSMY@204441|Rhodospirillales	204441|Rhodospirillales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
PYH1_k127_8205074_1	795666.MW7_1789	9.452e-165	533.0	COG1679@1|root,COG1679@2|Bacteria,1NFH4@1224|Proteobacteria,2VISW@28216|Betaproteobacteria,1KHHY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
PYH1_k127_8205074_8	795666.MW7_1790	8.918e-58	214.0	COG1786@1|root,COG1786@2|Bacteria,1RFUH@1224|Proteobacteria,2VSAS@28216|Betaproteobacteria,1KBB8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
PYH1_k127_8205074_11	93220.LV28_21090	5.126e-15	85.0	COG2913@1|root,COG2913@2|Bacteria,1RBY9@1224|Proteobacteria,2VSW7@28216|Betaproteobacteria,1K4ZB@119060|Burkholderiaceae	28216|Betaproteobacteria	J	(Lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
PYH1_k127_8205074_6	1442599.JAAN01000046_gene2710	1.908e-67	233.0	COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria,1X3N8@135614|Xanthomonadales	135614|Xanthomonadales	L	Preprotein translocase subunit TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
PYH1_k127_8215748_2	580332.Slit_1498	1.359e-53	193.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2VN3A@28216|Betaproteobacteria,44VNG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	nnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH1_k127_8215748_3	640081.Dsui_2224	6.144e-38	147.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VW5P@28216|Betaproteobacteria,2KXN3@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
PYH1_k127_8215748_0	580332.Slit_0650	1.231e-194	615.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,44V8Z@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
PYH1_k127_8215748_1	1000565.METUNv1_02400	5.359e-57	203.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,2KWBU@206389|Rhodocyclales	206389|Rhodocyclales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
PYH1_k127_8215748_4	1121015.N789_11455	2.305e-22	105.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1X30V@135614|Xanthomonadales	135614|Xanthomonadales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
PYH1_k127_8220765_12	596154.Alide2_2946	2.485e-68	237.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,4A9U8@80864|Comamonadaceae	28216|Betaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
PYH1_k127_8220765_5	987059.RBXJA2T_10319	1.169e-98	325.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,1KJWW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
PYH1_k127_8220765_0	1121035.AUCH01000015_gene2616	4.7e-322	997.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,2KV9E@206389|Rhodocyclales	206389|Rhodocyclales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
PYH1_k127_8220765_19	261292.Nit79A3_0363	1.102e-21	110.0	2EE49@1|root,337YY@2|Bacteria,1NE01@1224|Proteobacteria,2WGY9@28216|Betaproteobacteria,3736S@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
PYH1_k127_8220765_20	1123053.AUDG01000021_gene509	1.025e-15	91.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
PYH1_k127_8220765_14	1298867.AUES01000085_gene3659	4.201e-62	226.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_8220765_1	614083.AWQR01000005_gene1247	5.742e-300	936.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2VJ5N@28216|Betaproteobacteria,4AD5B@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Alkyl sulfatase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,GMC_oxred_C,GMC_oxred_N,Lactamase_B
PYH1_k127_8220765_13	1038860.AXAP01000082_gene501	2.485e-65	231.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria,3JUX0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
PYH1_k127_8220765_4	1217718.ALOU01000076_gene3960	5.707e-134	434.0	COG4188@1|root,COG4188@2|Bacteria,1MW2N@1224|Proteobacteria,2VSKA@28216|Betaproteobacteria,1K3U9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Hydrolase_4,PAF-AH_p_II
PYH1_k127_8220765_16	1298867.AUES01000085_gene3659	2.458e-52	208.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_8220765_18	439375.Oant_4408	6.715e-28	117.0	COG3791@1|root,COG3791@2|Bacteria,1N023@1224|Proteobacteria,2UC7M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
PYH1_k127_8220765_11	189753.AXAS01000041_gene2534	1.064e-69	250.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_8220765_8	1268622.AVS7_00745	1.645e-80	284.0	COG3181@1|root,COG3181@2|Bacteria,1NRBK@1224|Proteobacteria,2VZGQ@28216|Betaproteobacteria,4AGB2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_8220765_6	1215092.PA6_004_00670	2.439e-92	314.0	COG0604@1|root,COG0604@2|Bacteria,1MXCV@1224|Proteobacteria,1S13Q@1236|Gammaproteobacteria,1YCZ2@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH1_k127_8220765_2	1454004.AW11_03482	4.031e-221	705.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Ferrous iron transport protein B	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
PYH1_k127_8220765_7	189753.AXAS01000041_gene2534	1.967e-82	285.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_8220765_15	159087.Daro_4183	5.9e-55	203.0	COG3971@1|root,COG3971@2|Bacteria,1R3UP@1224|Proteobacteria,2VNA2@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	hydratase decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8220765_10	189753.AXAS01000041_gene2534	8.121e-71	250.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH1_k127_8220765_3	1242864.D187_003235	1.662e-200	640.0	COG1297@1|root,COG1297@2|Bacteria,1NQQP@1224|Proteobacteria,438FD@68525|delta/epsilon subdivisions,2X3QD@28221|Deltaproteobacteria,2YWUD@29|Myxococcales	28221|Deltaproteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
PYH1_k127_8220765_9	1088721.NSU_0979	4.888e-72	253.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2TSPC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
PYH1_k127_8220765_17	1095769.CAHF01000006_gene1951	1.023e-30	132.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VRIK@28216|Betaproteobacteria,4727E@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
PYH1_k127_8224793_3	767434.Fraau_0106	6.015e-21	100.0	COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria,1X3N8@135614|Xanthomonadales	135614|Xanthomonadales	L	Preprotein translocase subunit TatD	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
PYH1_k127_8224793_0	305700.B447_05513	4.981e-93	317.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria,2KUN0@206389|Rhodocyclales	206389|Rhodocyclales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
PYH1_k127_8224793_1	1454004.AW11_00290	3.31e-85	289.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria,1KR7M@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
PYH1_k127_8224793_2	1286093.C266_04799	2.75e-43	169.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,1K2RA@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
PYH1_k127_8247101_12	1430440.MGMSRv2_1302	5.178e-24	118.0	COG1959@1|root,COG1959@2|Bacteria,1PZ79@1224|Proteobacteria,2UCUA@28211|Alphaproteobacteria,2JTF5@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
PYH1_k127_8247101_10	1150469.RSPPHO_01831	9.403e-46	170.0	COG0454@1|root,COG0456@2|Bacteria,1N43K@1224|Proteobacteria,2UDB6@28211|Alphaproteobacteria,2JTG2@204441|Rhodospirillales	204441|Rhodospirillales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PYH1_k127_8247101_2	1123255.JHYS01000007_gene1673	1.889e-157	504.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2VHP9@28216|Betaproteobacteria,4ACT4@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_8247101_3	1316936.K678_04216	7.737e-118	385.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,2JPSA@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_8247101_4	1150626.PHAMO_270062	7.513e-117	383.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,2JPIB@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_8247101_7	1279038.KB907339_gene1290	5.49e-87	316.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,2JR23@204441|Rhodospirillales	204441|Rhodospirillales	E	branched-chain amino acid transport	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH1_k127_8247101_6	1437824.BN940_02581	2.434e-97	327.0	COG0410@1|root,COG3945@1|root,COG0410@2|Bacteria,COG3945@2|Bacteria,1MVVC@1224|Proteobacteria,2VK1I@28216|Betaproteobacteria,3T8K4@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,Hemerythrin
PYH1_k127_8247101_11	1380394.JADL01000002_gene1592	2.749e-45	167.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria,2JUEU@204441|Rhodospirillales	204441|Rhodospirillales	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8247101_0	85643.Tmz1t_2959	0.0	1279.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VMWP@28216|Betaproteobacteria,2KVYZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.5.1,3.1.2.25	ko:K18361	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
PYH1_k127_8247101_5	62928.azo1947	7.628e-109	368.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,2KXUS@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	ko:K18362	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	-
PYH1_k127_8247101_9	62928.azo1948	1.502e-56	216.0	COG3302@1|root,COG3302@2|Bacteria,1N8SU@1224|Proteobacteria,2WGE7@28216|Betaproteobacteria,2M04N@206389|Rhodocyclales	206389|Rhodocyclales	S	DMSO reductase anchor subunit (DmsC)	-	-	-	ko:K18363	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	DmsC
PYH1_k127_8247101_1	1380394.JADL01000002_gene1594	2.599e-188	598.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,2JQ5N@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
PYH1_k127_8247101_8	1430440.MGMSRv2_0273	2.871e-69	253.0	COG3278@1|root,COG3278@2|Bacteria,1PU2D@1224|Proteobacteria,2U5ID@28211|Alphaproteobacteria,2JS12@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8247101_13	258594.RPA2070	6.609e-08	57.0	2E0AX@1|root,32VY8@2|Bacteria,1N21Q@1224|Proteobacteria,2UECC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
PYH1_k127_8251525_19	1232410.KI421423_gene1912	0.0001621	46.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WQFN@28221|Deltaproteobacteria,43VRT@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,POR
PYH1_k127_8251525_2	1232410.KI421423_gene1911	2.173e-137	457.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,43TQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
PYH1_k127_8251525_0	767817.Desgi_1127	2.571e-151	508.0	COG0674@1|root,COG0674@2|Bacteria,1VS48@1239|Firmicutes,25E5U@186801|Clostridia,261NS@186807|Peptococcaceae	186801|Clostridia	C	2-oxoacid ferredoxin oxidoreductase, alpha subunit	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
PYH1_k127_8251525_3	767817.Desgi_1128	2.714e-96	340.0	COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,261RJ@186807|Peptococcaceae	186801|Clostridia	C	PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
PYH1_k127_8251525_6	237368.SCABRO_00086	5.088e-64	227.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K10742	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_24,PDDEXK_1
PYH1_k127_8251525_8	1123368.AUIS01000010_gene2357	1.686e-58	223.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,2NCV9@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
PYH1_k127_8251525_1	1205680.CAKO01000029_gene4978	5.521e-144	465.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JPPM@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_8251525_7	342113.DM82_245	1.77e-62	223.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,1K2GU@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
PYH1_k127_8251525_16	1169143.KB911038_gene6003	7.285e-34	133.0	2AY99@1|root,31QBJ@2|Bacteria,1RI92@1224|Proteobacteria,2VSPH@28216|Betaproteobacteria,1K7SH@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8251525_15	1123487.KB892836_gene3171	7.477e-39	147.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,2KWRE@206389|Rhodocyclales	206389|Rhodocyclales	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
PYH1_k127_8251525_12	366602.Caul_0177	4.839e-45	175.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2UBYB@28211|Alphaproteobacteria,2KHAG@204458|Caulobacterales	204458|Caulobacterales	T	TspO MBR family protein	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
PYH1_k127_8251525_11	522306.CAP2UW1_2655	4.645e-49	184.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2VRJE@28216|Betaproteobacteria,1KQX4@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
PYH1_k127_8251525_5	1123257.AUFV01000009_gene2259	2.026e-68	246.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,1XC3C@135614|Xanthomonadales	135614|Xanthomonadales	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
PYH1_k127_8251525_4	1288494.EBAPG3_10670	2.662e-93	310.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria,372KE@32003|Nitrosomonadales	28216|Betaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
PYH1_k127_8251525_17	375286.mma_3515	2.059e-30	123.0	2AY99@1|root,31QBJ@2|Bacteria,1RI92@1224|Proteobacteria,2VSPH@28216|Betaproteobacteria,474NZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8251525_18	1454004.AW11_01049	1.971e-18	89.0	COG2329@1|root,COG2329@2|Bacteria,1NDM8@1224|Proteobacteria,2VXVH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
PYH1_k127_8251525_10	1121035.AUCH01000013_gene3108	3.827e-51	184.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2VSN0@28216|Betaproteobacteria,2KWPR@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
PYH1_k127_8251525_9	882.DVU_1082	3.315e-53	193.0	COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,42S18@68525|delta/epsilon subdivisions,2WN9J@28221|Deltaproteobacteria,2MAMV@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
PYH1_k127_8251525_13	535289.Dtpsy_2804	1.386e-42	168.0	COG1787@1|root,COG1787@2|Bacteria,1RGGQ@1224|Proteobacteria,2VTJ4@28216|Betaproteobacteria,4AF75@80864|Comamonadaceae	28216|Betaproteobacteria	V	PFAM Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
PYH1_k127_8251525_14	1163409.UUA_13285	1.492e-41	155.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1X4YF@135614|Xanthomonadales	135614|Xanthomonadales	S	Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
PYH1_k127_8252608_33	1282876.BAOK01000001_gene3369	1.941e-09	58.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2TR1Y@28211|Alphaproteobacteria,4BP9W@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	yejE	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
PYH1_k127_8252608_2	864069.MicloDRAFT_00062840	4.158e-213	680.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,1JRYY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	gsiA1	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH1_k127_8252608_1	331869.BAL199_10602	2.115e-252	794.0	COG0747@1|root,COG0747@2|Bacteria,1MU3P@1224|Proteobacteria,2TT4M@28211|Alphaproteobacteria,4BPY6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH1_k127_8252608_9	1380394.JADL01000001_gene2044	1.625e-143	462.0	COG0601@1|root,COG0601@2|Bacteria,1MWXF@1224|Proteobacteria,2TR7C@28211|Alphaproteobacteria,2JQ7B@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH1_k127_8252608_4	1121033.AUCF01000003_gene3332	3.234e-189	602.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TUWG@28211|Alphaproteobacteria,2JQ92@204441|Rhodospirillales	204441|Rhodospirillales	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PYH1_k127_8252608_16	1110502.TMO_0853	2.349e-109	361.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,2U14Z@28211|Alphaproteobacteria,2JPB8@204441|Rhodospirillales	204441|Rhodospirillales	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
PYH1_k127_8252608_0	1205680.CAKO01000040_gene612	2.685e-272	865.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,2TRSY@28211|Alphaproteobacteria,2JPPS@204441|Rhodospirillales	204441|Rhodospirillales	V	ABC transporter transmembrane region	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran,cNMP_binding
PYH1_k127_8252608_32	1122135.KB893134_gene3197	9.594e-38	148.0	COG0664@1|root,COG0664@2|Bacteria,1RI6M@1224|Proteobacteria,2U9WH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
PYH1_k127_8252608_23	420662.Mpe_A3124	2.221e-61	215.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,1KKYS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
PYH1_k127_8252608_22	946483.Cenrod_1259	5.174e-64	221.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,4ADH4@80864|Comamonadaceae	28216|Betaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
PYH1_k127_8252608_25	1000565.METUNv1_02882	2.794e-60	210.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,2KWFU@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
PYH1_k127_8252608_7	1123392.AQWL01000022_gene2179	1.289e-165	529.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,1KRDK@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
PYH1_k127_8252608_28	640081.Dsui_1332	5.581e-49	189.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VVJ7@28216|Betaproteobacteria,2KX2H@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8252608_29	640081.Dsui_1333	1.021e-48	177.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,2KWWR@206389|Rhodocyclales	206389|Rhodocyclales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
PYH1_k127_8252608_24	1454004.AW11_04004	3.72e-61	216.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,1KQ1R@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
PYH1_k127_8252608_13	1163617.SCD_n02516	4.004e-113	394.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
PYH1_k127_8252608_14	580332.Slit_2450	3.698e-112	376.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,44V44@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
PYH1_k127_8252608_5	1123392.AQWL01000022_gene2175	8.742e-176	563.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,1KSWW@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
PYH1_k127_8252608_17	391735.Veis_2976	3.063e-106	369.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,2VJ0Y@28216|Betaproteobacteria,4AE5W@80864|Comamonadaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PYH1_k127_8252608_8	1038859.AXAU01000007_gene5808	1.174e-160	514.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_8252608_6	318996.AXAZ01000001_gene4884	2.207e-173	551.0	COG4663@1|root,COG4663@2|Bacteria,1R40U@1224|Proteobacteria,2U3KB@28211|Alphaproteobacteria,3K34G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH1_k127_8252608_19	1038859.AXAU01000001_gene3650	7.484e-79	266.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2UBPX@28211|Alphaproteobacteria,3K2R5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH1_k127_8252608_3	318996.AXAZ01000001_gene4882	1.923e-197	626.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,3JTY7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
PYH1_k127_8252608_12	667121.ET1_03_00900	1.58e-117	390.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,1RP58@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	patB	-	4.4.1.8	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH1_k127_8252608_30	426117.M446_3248	3.589e-42	171.0	COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2U7C6@28211|Alphaproteobacteria,1JUKF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	chaC	-	-	ko:K07232	-	-	-	-	ko00000	-	-	-	ChaC
PYH1_k127_8252608_15	460265.Mnod_3440	7.047e-111	367.0	COG3246@1|root,COG3246@2|Bacteria,1R4YF@1224|Proteobacteria,2TVC8@28211|Alphaproteobacteria,1JX4G@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Pfam:Kce	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
PYH1_k127_8252608_10	1122132.AQYH01000008_gene2391	5.26e-133	432.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,4B8Y5@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	sulfite oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
PYH1_k127_8252608_26	113395.AXAI01000013_gene6713	8.411e-60	213.0	COG4032@1|root,COG4032@2|Bacteria,1P0HU@1224|Proteobacteria,2TRJ2@28211|Alphaproteobacteria,3JQMU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
PYH1_k127_8252608_21	1380394.JADL01000001_gene2567	8.162e-65	235.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TXAJ@28211|Alphaproteobacteria,2JWX2@204441|Rhodospirillales	204441|Rhodospirillales	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
PYH1_k127_8252608_11	62928.azo0103	1.659e-128	420.0	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,2VKGI@28216|Betaproteobacteria,2KW58@206389|Rhodocyclales	206389|Rhodocyclales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PYH1_k127_8252608_31	1163617.SCD_n01141	1.304e-41	160.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2VWK8@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
PYH1_k127_8252608_27	1123504.JQKD01000005_gene4741	5.698e-51	191.0	COG2230@1|root,COG2230@2|Bacteria,1QX5S@1224|Proteobacteria,2WHKW@28216|Betaproteobacteria,4AJZM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
PYH1_k127_8252608_18	1532557.JL37_10320	2.903e-95	328.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VZNH@28216|Betaproteobacteria,3T57A@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_8252608_20	426355.Mrad2831_5983	4.125e-69	239.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,1JQSM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH1_k127_8254018_0	76114.ebA2092	7.6e-59	224.0	COG1703@1|root,COG1975@1|root,COG1703@2|Bacteria,COG1975@2|Bacteria,1MVI0@1224|Proteobacteria,2VIRF@28216|Betaproteobacteria,2KVDF@206389|Rhodocyclales	28216|Betaproteobacteria	E	periplasmic protein kinase ArgK and related GTPases of G3E family	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
PYH1_k127_8254018_1	562970.Btus_1408	3.819e-50	198.0	COG1085@1|root,COG1085@2|Bacteria,1V675@1239|Firmicutes,4HVRJ@91061|Bacilli	91061|Bacilli	C	galactose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8266539_1	640081.Dsui_3059	0.0	1055.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,2KU76@206389|Rhodocyclales	206389|Rhodocyclales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PYH1_k127_8266539_9	1454004.AW11_00832	3.721e-59	225.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,1KQ01@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
PYH1_k127_8266539_3	1205680.CAKO01000038_gene1877	6.701e-103	343.0	COG1132@1|root,COG1132@2|Bacteria,1R5NG@1224|Proteobacteria,2U22C@28211|Alphaproteobacteria,2JWNJ@204441|Rhodospirillales	204441|Rhodospirillales	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8266539_5	568706.BN118_0303	4.693e-70	244.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2VK1C@28216|Betaproteobacteria,3T3EF@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ygfF	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH1_k127_8266539_2	1100720.ALKN01000030_gene1115	2.44e-146	471.0	COG3181@1|root,COG3181@2|Bacteria,1R4PJ@1224|Proteobacteria,2VNY9@28216|Betaproteobacteria,4ACK2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_8266539_10	1265502.KB905929_gene2312	2.785e-50	185.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,4ADKA@80864|Comamonadaceae	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
PYH1_k127_8266539_13	314278.NB231_07442	1.588e-39	153.0	2E3RZ@1|root,32YPK@2|Bacteria,1NJYT@1224|Proteobacteria,1SHP1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8266539_6	497321.C664_02725	1.11e-68	238.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,2KUSV@206389|Rhodocyclales	206389|Rhodocyclales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
PYH1_k127_8266539_0	1288494.EBAPG3_4370	0.0	1672.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,372Q5@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
PYH1_k127_8266539_12	546264.NEIFLAOT_00784	8.217e-42	171.0	2EHAS@1|root,33B2M@2|Bacteria,1NZNX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_8266539_4	85643.Tmz1t_1729	2.175e-85	292.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,2KUZX@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
PYH1_k127_8266539_14	1163617.SCD_n00916	2.974e-33	136.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
PYH1_k127_8266539_7	261292.Nit79A3_1152	1.916e-65	229.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,37316@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
PYH1_k127_8266539_11	497321.C664_16540	9.01e-50	183.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,2VQ6X@28216|Betaproteobacteria,2KW4E@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
PYH1_k127_8266539_8	1192124.LIG30_1818	6.195e-62	218.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,1K174@119060|Burkholderiaceae	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
PYH1_k127_8328198_2	1123393.KB891316_gene1156	1.785e-31	125.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,1KRIS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
PYH1_k127_8328198_0	398767.Glov_1508	2.538e-196	625.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WJEW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	capL	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K02474,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
PYH1_k127_8328198_1	1223521.BBJX01000001_gene934	1.848e-32	127.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,4ABTQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
PYH1_k127_83489_0	640081.Dsui_3344	3.382e-196	637.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,2KUJY@206389|Rhodocyclales	206389|Rhodocyclales	G	Phosphoglucomutase	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PYH1_k127_83489_1	522306.CAP2UW1_2942	1.357e-98	338.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2VHZ1@28216|Betaproteobacteria,1KQM2@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
PYH1_k127_83489_3	748247.AZKH_1028	3.876e-37	152.0	COG3631@1|root,COG3631@2|Bacteria,1QXIX@1224|Proteobacteria,2WH4R@28216|Betaproteobacteria,2KZY7@206389|Rhodocyclales	206389|Rhodocyclales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
PYH1_k127_83489_2	1031711.RSPO_c02798	7.177e-53	191.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,1K2BX@119060|Burkholderiaceae	28216|Betaproteobacteria	M	heptosyltransferase II	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
PYH1_k127_8348974_4	522306.CAP2UW1_4122	5.319e-12	68.0	2E95F@1|root,333E6@2|Bacteria,1N8N7@1224|Proteobacteria,2VWBC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3619)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3619
PYH1_k127_8348974_2	1288494.EBAPG3_13520	2.449e-25	114.0	2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,373GC@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
PYH1_k127_8348974_3	261292.Nit79A3_0707	7.608e-24	112.0	COG1714@1|root,COG1714@2|Bacteria,1REEC@1224|Proteobacteria,2VRE0@28216|Betaproteobacteria,3738E@32003|Nitrosomonadales	28216|Betaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
PYH1_k127_8348974_0	1163617.SCD_n00813	3.535e-110	383.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
PYH1_k127_8348974_1	640081.Dsui_3535	3.749e-110	369.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,2KVN9@206389|Rhodocyclales	206389|Rhodocyclales	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
PYH1_k127_852242_0	215803.DB30_0841	1.333e-102	370.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,438M3@68525|delta/epsilon subdivisions,2X1ZS@28221|Deltaproteobacteria,2YX8A@29|Myxococcales	28221|Deltaproteobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,TPR_12
PYH1_k127_852242_4	1090320.KB900605_gene2836	1.532e-37	157.0	COG0457@1|root,COG3577@1|root,COG0457@2|Bacteria,COG3577@2|Bacteria,1MVIW@1224|Proteobacteria,2TV3Y@28211|Alphaproteobacteria,2KCMD@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
PYH1_k127_852242_1	1038860.AXAP01000001_gene6354	5.24e-89	308.0	COG0683@1|root,COG0683@2|Bacteria,1QENW@1224|Proteobacteria,2U0CK@28211|Alphaproteobacteria,3K48H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_852242_2	587753.EY04_18980	1.929e-83	287.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,1RZNQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_852242_3	1232683.ADIMK_1647	3.586e-70	259.0	COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,1S0TW@1236|Gammaproteobacteria,46CPQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_852242_5	1449351.RISW2_15690	4.414e-25	119.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSWS@28211|Alphaproteobacteria,4KK4G@93682|Roseivivax	28211|Alphaproteobacteria	E	branched-chain amino acid	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_938248_2	694431.DESACE_07195	1.284e-15	81.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2789,iNRG857_1313.NRG857_06920	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
PYH1_k127_938248_1	1173026.Glo7428_3186	1.204e-30	130.0	COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
PYH1_k127_938248_0	1286093.C266_14437	1.616e-46	175.0	COG0583@1|root,COG0583@2|Bacteria,1MV0E@1224|Proteobacteria,2VM44@28216|Betaproteobacteria,1K2UV@119060|Burkholderiaceae	28216|Betaproteobacteria	K	transcriptional Regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH1_k127_940560_12	1163617.SCD_n00572	6.379e-46	173.0	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,2VQFW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
PYH1_k127_940560_0	1123487.KB892846_gene567	1.075e-241	759.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KUQA@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
PYH1_k127_940560_2	640081.Dsui_1392	1.426e-152	492.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VI1J@28216|Betaproteobacteria,2KU71@206389|Rhodocyclales	206389|Rhodocyclales	NU	type II secretion system protein	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
PYH1_k127_940560_6	1454004.AW11_03600	1.532e-70	258.0	2CG4C@1|root,2Z8MQ@2|Bacteria,1R6PQ@1224|Proteobacteria,2VHKG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_940560_16	640081.Dsui_1390	5.374e-25	114.0	2E6RE@1|root,331BH@2|Bacteria,1N8K0@1224|Proteobacteria,2VWUF@28216|Betaproteobacteria,2KXGE@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_940560_17	522306.CAP2UW1_0630	3.999e-15	82.0	2DTBA@1|root,33JIB@2|Bacteria,1NKRT@1224|Proteobacteria,2VY45@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_940560_13	1304883.KI912532_gene1639	1.723e-33	148.0	COG2165@1|root,COG2165@2|Bacteria,1N7CG@1224|Proteobacteria	1224|Proteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_940560_11	159087.Daro_3413	2.958e-48	191.0	COG2165@1|root,COG2165@2|Bacteria,1RIBU@1224|Proteobacteria,2WFDS@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
PYH1_k127_940560_3	1454004.AW11_03606	1.023e-135	451.0	COG0642@1|root,COG0642@2|Bacteria,1R49A@1224|Proteobacteria,2VKU5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
PYH1_k127_940560_7	1198452.Jab_2c02510	4.552e-66	236.0	2EMEM@1|root,33F3F@2|Bacteria,1NK08@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_940560_9	1121035.AUCH01000003_gene1203	2.739e-54	198.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,2VR8U@28216|Betaproteobacteria,2KWCN@206389|Rhodocyclales	206389|Rhodocyclales	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
PYH1_k127_940560_1	640081.Dsui_1383	7.992e-223	709.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,2KUCM@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
PYH1_k127_940560_4	640081.Dsui_1382	3.946e-127	414.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,2KV61@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
PYH1_k127_940560_10	76114.ebA1316	1.885e-52	198.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,2KWGX@206389|Rhodocyclales	206389|Rhodocyclales	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
PYH1_k127_940560_15	582744.Msip34_0205	4.923e-26	121.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria,2KMR4@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
PYH1_k127_940560_14	1236959.BAMT01000006_gene330	3.514e-31	137.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,2KMKV@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
PYH1_k127_940560_5	1000565.METUNv1_03643	1.741e-108	367.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,2KUNS@206389|Rhodocyclales	206389|Rhodocyclales	S	ABC-type (Unclassified) transport system, ATPase component	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
PYH1_k127_940560_18	1288494.EBAPG3_7410	1.209e-14	77.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,371WJ@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
PYH1_k127_952758_9	1304883.KI912532_gene2392	1.264e-37	149.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,2KUWP@206389|Rhodocyclales	206389|Rhodocyclales	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
PYH1_k127_952758_11	981223.AIED01000149_gene464	8.718e-16	79.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,3NQBV@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_952758_10	640511.BC1002_1458	5.214e-32	126.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,1K8CW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
PYH1_k127_952758_0	323848.Nmul_A2338	0.0	1234.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,3727H@32003|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
PYH1_k127_952758_1	1000565.METUNv1_00037	3.563e-215	673.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,2KVAQ@206389|Rhodocyclales	206389|Rhodocyclales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
PYH1_k127_952758_6	1123392.AQWL01000008_gene1182	1.95e-103	349.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,1KRDV@119069|Hydrogenophilales	119069|Hydrogenophilales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
PYH1_k127_952758_3	1123367.C666_17020	2.066e-145	473.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,2KU9B@206389|Rhodocyclales	206389|Rhodocyclales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
PYH1_k127_952758_7	62928.azo1883	2.424e-100	340.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,2KUC0@206389|Rhodocyclales	206389|Rhodocyclales	I	phytoene	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
PYH1_k127_952758_4	94624.Bpet3164	1.9e-122	398.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,3T34J@506|Alcaligenaceae	28216|Betaproteobacteria	I	Phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
PYH1_k127_952758_8	62928.azo1885	4.741e-91	327.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,2KVAB@206389|Rhodocyclales	206389|Rhodocyclales	H	squalene-associated FAD-dependent desaturase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
PYH1_k127_952758_5	614083.AWQR01000003_gene2919	4.552e-120	401.0	COG0596@1|root,COG0596@2|Bacteria,1QXWE@1224|Proteobacteria,2WHZX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
PYH1_k127_952758_2	1163617.SCD_n01785	2.49e-165	526.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria	28216|Betaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
PYH1_k127_980115_3	1100720.ALKN01000033_gene730	3.387e-195	615.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2VHXC@28216|Betaproteobacteria,4AB9R@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH1_k127_980115_6	935261.JAGL01000001_gene1774	1.453e-155	495.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2TSIQ@28211|Alphaproteobacteria,43HTT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_980115_7	935261.JAGL01000001_gene1775	9.135e-138	444.0	COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,2TR99@28211|Alphaproteobacteria,43GRP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH1_k127_980115_10	1408418.JNJH01000004_gene1994	4.655e-102	336.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,2TUVZ@28211|Alphaproteobacteria,2JZMQ@204441|Rhodospirillales	204441|Rhodospirillales	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
PYH1_k127_980115_0	1408418.JNJH01000004_gene1993	7.485e-222	709.0	COG2252@1|root,COG2252@2|Bacteria,1QVW3@1224|Proteobacteria,2TWKP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PERMEase	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
PYH1_k127_980115_2	757424.Hsero_2798	7.434e-205	651.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2VKD1@28216|Betaproteobacteria,475B2@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	acd12	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH1_k127_980115_11	543728.Vapar_1313	8.435e-99	328.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2VMR4@28216|Betaproteobacteria,4ABKB@80864|Comamonadaceae	28216|Betaproteobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PYH1_k127_980115_13	1007105.PT7_0650	4.865e-92	327.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T21B@506|Alcaligenaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_980115_9	1205680.CAKO01000037_gene1191	6.264e-118	387.0	COG3181@1|root,COG3181@2|Bacteria,1NPUE@1224|Proteobacteria,2UPPQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_980115_4	1121106.JQKB01000080_gene2757	9.664e-179	568.0	COG4948@1|root,COG4948@2|Bacteria,1MW3F@1224|Proteobacteria,2U1H9@28211|Alphaproteobacteria,2JYT0@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
PYH1_k127_980115_14	1123060.JONP01000026_gene3446	1.562e-77	290.0	COG0111@1|root,COG0111@2|Bacteria,1RAVY@1224|Proteobacteria,2U5YH@28211|Alphaproteobacteria,2JZG0@204441|Rhodospirillales	204441|Rhodospirillales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH1_k127_980115_5	1095769.CAHF01000006_gene1956	1.888e-166	550.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,475Y7@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
PYH1_k127_980115_1	1121106.JQKB01000020_gene2016	2.505e-205	653.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQU2@28211|Alphaproteobacteria,2JV5K@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
PYH1_k127_980115_12	596154.Alide2_3931	3.837e-92	322.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH1_k127_980115_8	977880.RALTA_B0538	1.836e-128	415.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2VJQ2@28216|Betaproteobacteria,1KGKB@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
PYH1_k127_997494_1	56780.SYN_02218	1.974e-109	383.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
PYH1_k127_997494_0	535289.Dtpsy_1299	4.101e-158	514.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,4A9N8@80864|Comamonadaceae	28216|Betaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
PYH1_k127_997494_3	1288494.EBAPG3_12200	2.79e-09	61.0	COG2010@1|root,COG2010@2|Bacteria,1NF1C@1224|Proteobacteria,2VVP1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH1_k127_997494_4	1123487.KB892841_gene4270	0.0001746	44.0	COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,2VTYE@28216|Betaproteobacteria,2KX1A@206389|Rhodocyclales	206389|Rhodocyclales	S	FixH family	-	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
## 3401 queries scanned
## Total time (seconds): 107.64968705177307
## Rate: 31.59 q/s